Clone Name | rbasd2f06 |
---|---|
Clone Library Name | barley_pub |
>FA62A_PONPY (Q5RAG2) Protein FAM62A| Length = 1104 Score = 67.0 bits (162), Expect = 4e-11 Identities = 42/124 (33%), Positives = 61/124 (49%), Gaps = 6/124 (4%) Frame = -1 Query: 568 TRGVLSVTVISAEDIPAMD------VMGKADPFVVLYLXXXXXXXXXXXXXXTLNPIWNQ 407 T VL + V+ A+D+ A D V GK+DP+V L L LNP WN+ Sbjct: 645 TEHVLRIHVLEAQDLIAKDRFLGGLVKGKSDPYVKLKLAGRSFRSHVVRED--LNPRWNE 702 Query: 406 TFDFVVEDALHDLLMVEVWDHDTFGKDYIGRCILTLTRAILEGEFQDTYALQGAKSGRLN 227 F+ +V L VEV+D D D++GRC ++LT + G + L+ SGRL+ Sbjct: 703 VFEVIVTSVPGQELEVEVFDKDLDKDDFLGRCKVSLTTVLNSGFLDEWLTLEDVPSGRLH 762 Query: 226 LHFK 215 L + Sbjct: 763 LRLE 766 Score = 61.6 bits (148), Expect = 2e-09 Identities = 35/134 (26%), Positives = 69/134 (51%), Gaps = 6/134 (4%) Frame = -1 Query: 595 DVNQRKNVITRGVLSVTVISAEDIPAMD------VMGKADPFVVLYLXXXXXXXXXXXXX 434 DV Q ++ + RG++ + +++A + + D + GK+DP+ ++ L Sbjct: 318 DVAQLRSPLPRGIIRIHLLAARGLTSKDKYVKGLIEGKSDPYALVRLGTQTFCSRVIDEE 377 Query: 433 XTLNPIWNQTFDFVVEDALHDLLMVEVWDHDTFGKDYIGRCILTLTRAILEGEFQDTYAL 254 LNP W +T++ +V + + VEV+D D D++GR L + + + G D + L Sbjct: 378 --LNPQWGETYEVMVHEVPGQEIEVEVFDKDPDKDDFLGRMKLDVGKVLQAGVLDDWFPL 435 Query: 253 QGAKSGRLNLHFKW 212 QG + G+++L +W Sbjct: 436 QGGQ-GQVHLRLEW 448
>FA62A_HUMAN (Q9BSJ8) Protein FAM62A (Membrane bound C2 domain-containing protein)| Length = 1104 Score = 66.2 bits (160), Expect = 7e-11 Identities = 42/124 (33%), Positives = 60/124 (48%), Gaps = 6/124 (4%) Frame = -1 Query: 568 TRGVLSVTVISAEDIPAMD------VMGKADPFVVLYLXXXXXXXXXXXXXXTLNPIWNQ 407 T VL + V+ A+D+ A D V GK+DP+V L L LNP WN+ Sbjct: 645 TEHVLRIHVLEAQDLIAKDRFLGGLVKGKSDPYVKLKLAGRSFRSHVVRED--LNPRWNE 702 Query: 406 TFDFVVEDALHDLLMVEVWDHDTFGKDYIGRCILTLTRAILEGEFQDTYALQGAKSGRLN 227 F+ +V L VEV+D D D++GRC + LT + G + L+ SGRL+ Sbjct: 703 VFEVIVTSVPGQELEVEVFDKDLDKDDFLGRCKVRLTTVLNSGFLDEWLTLEDVPSGRLH 762 Query: 226 LHFK 215 L + Sbjct: 763 LRLE 766 Score = 59.3 bits (142), Expect = 9e-09 Identities = 34/134 (25%), Positives = 68/134 (50%), Gaps = 6/134 (4%) Frame = -1 Query: 595 DVNQRKNVITRGVLSVTVISAEDIPAMD------VMGKADPFVVLYLXXXXXXXXXXXXX 434 DV Q ++ + RG++ + +++A + + D + GK+DP+ ++ L Sbjct: 318 DVAQLRSPLPRGIIRIHLLAARGLSSKDKYVKGLIEGKSDPYALVRLGTQTFCSRVIDEE 377 Query: 433 XTLNPIWNQTFDFVVEDALHDLLMVEVWDHDTFGKDYIGRCILTLTRAILEGEFQDTYAL 254 LNP W +T++ +V + + VEV+D D D++GR L + + + D + L Sbjct: 378 --LNPQWGETYEVMVHEVPGQEIEVEVFDKDPDKDDFLGRMKLDVGKVLQASVLDDWFPL 435 Query: 253 QGAKSGRLNLHFKW 212 QG + G+++L +W Sbjct: 436 QGGQ-GQVHLRLEW 448
>FA62A_MOUSE (Q3U7R1) Protein FAM62A (Membrane bound C2 domain-containing protein)| Length = 1092 Score = 62.0 bits (149), Expect = 1e-09 Identities = 40/134 (29%), Positives = 62/134 (46%), Gaps = 6/134 (4%) Frame = -1 Query: 598 YDVNQRKNVITRGVLSVTVISAEDIPAMD------VMGKADPFVVLYLXXXXXXXXXXXX 437 Y + T VL + V+ A+D+ A D V GK+DP+V L + Sbjct: 622 YHTTPNSHFGTENVLRIHVLEAQDLIAKDRFLGGLVKGKSDPYVKLKVAGKSFRTHVVRE 681 Query: 436 XXTLNPIWNQTFDFVVEDALHDLLMVEVWDHDTFGKDYIGRCILTLTRAILEGEFQDTYA 257 LNP WN+ F+ +V L +EV+D D D++GR ++LT + G + Sbjct: 682 D--LNPRWNEVFEVIVTSIPGQELEIEVFDKDLDKDDFLGRYKVSLTTVLNSGFLDEWLT 739 Query: 256 LQGAKSGRLNLHFK 215 L+ SGRL+L + Sbjct: 740 LEDVPSGRLHLRLE 753 Score = 60.8 bits (146), Expect = 3e-09 Identities = 34/134 (25%), Positives = 69/134 (51%), Gaps = 6/134 (4%) Frame = -1 Query: 595 DVNQRKNVITRGVLSVTVISAEDIPAMD------VMGKADPFVVLYLXXXXXXXXXXXXX 434 DV Q ++ + RG++ + +++A + + D + GK+DP+ ++ + Sbjct: 308 DVAQLRSPLPRGIIRIHLLAARGLSSKDKYVKGLIEGKSDPYALVRVGTQTFCSRVIDEE 367 Query: 433 XTLNPIWNQTFDFVVEDALHDLLMVEVWDHDTFGKDYIGRCILTLTRAILEGEFQDTYAL 254 LNP W +T++ +V + + VEV+D D D++GR L + + + G + Y L Sbjct: 368 --LNPHWGETYEVIVHEVPGQEIEVEVFDKDPDKDDFLGRMKLDVGKVLQAGVLDNWYPL 425 Query: 253 QGAKSGRLNLHFKW 212 QG + G+++L +W Sbjct: 426 QGGQ-GQVHLRLEW 438
>FA62A_RAT (Q9Z1X1) Protein FAM62A (Membrane bound C2 domain-containing| protein) (vp115) Length = 1088 Score = 60.8 bits (146), Expect = 3e-09 Identities = 34/134 (25%), Positives = 69/134 (51%), Gaps = 6/134 (4%) Frame = -1 Query: 595 DVNQRKNVITRGVLSVTVISAEDIPAMD------VMGKADPFVVLYLXXXXXXXXXXXXX 434 DV Q ++ + RG++ + +++A + + D + GK+DP+ ++ + Sbjct: 310 DVAQLRSPLPRGIIRIHLLAARGLSSKDKYVKGLIEGKSDPYALVRVGTQTFCSRVIDEE 369 Query: 433 XTLNPIWNQTFDFVVEDALHDLLMVEVWDHDTFGKDYIGRCILTLTRAILEGEFQDTYAL 254 LNP W +T++ +V + + VEV+D D D++GR L + + + G + Y L Sbjct: 370 --LNPHWGETYEVIVHEVPGQEIEVEVFDKDPDKDDFLGRMKLDVGKVLQAGVLDNWYPL 427 Query: 253 QGAKSGRLNLHFKW 212 QG + G+++L +W Sbjct: 428 QGGQ-GQVHLRLEW 440 Score = 60.5 bits (145), Expect = 4e-09 Identities = 40/134 (29%), Positives = 61/134 (45%), Gaps = 6/134 (4%) Frame = -1 Query: 598 YDVNQRKNVITRGVLSVTVISAEDIPAMD------VMGKADPFVVLYLXXXXXXXXXXXX 437 Y + T VL + V+ A+D+ A D V GK+DP+V L + Sbjct: 624 YHTTPNSHFGTENVLRIHVLEAQDLIAKDRFLGGLVKGKSDPYVKLKVAGRSLRTHVVRE 683 Query: 436 XXTLNPIWNQTFDFVVEDALHDLLMVEVWDHDTFGKDYIGRCILTLTRAILEGEFQDTYA 257 LNP WN+ F+ +V L +EV+D D D++GR + LT + G + Sbjct: 684 D--LNPRWNEVFEVIVTSIPGQELDIEVFDKDLDKDDFLGRYKVGLTTVLNSGFLDEWLT 741 Query: 256 LQGAKSGRLNLHFK 215 L+ SGRL+L + Sbjct: 742 LEDVPSGRLHLRLE 755
>SYT1_CAEEL (P34693) Synaptotagmin-1 (Synaptotagmin I)| Length = 441 Score = 59.7 bits (143), Expect = 7e-09 Identities = 37/93 (39%), Positives = 53/93 (56%), Gaps = 4/93 (4%) Frame = -1 Query: 565 RGVLSVTVISAEDIPAMDVMGKADPFVVLYLX-XXXXXXXXXXXXXTLNPIWNQTFDFVV 389 +G L+VTVI AED+P MD+ G +DP+V LYL TLNP++N+TF F V Sbjct: 173 QGQLTVTVIQAEDLPGMDMSGTSDPYVKLYLLPEKKKKVETKVHRKTLNPVFNETFIFKV 232 Query: 388 --EDALHDLLMVEVWDHDTFGK-DYIGRCILTL 299 + L+ ++D D F K D IG+ ++ L Sbjct: 233 AFNEITAKTLVFAIYDFDRFSKHDQIGQVLIPL 265 Score = 51.6 bits (122), Expect = 2e-06 Identities = 35/96 (36%), Positives = 50/96 (52%), Gaps = 6/96 (6%) Frame = -1 Query: 574 VITRGVLSVTVISAEDIPAMDVMGKADPFVVLYLXXXXXXXXXXXXXX---TLNPIWNQT 404 V T G L+V ++ A+++ MDV G +DP+V + L TLNP +N++ Sbjct: 303 VPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIVLMQGGKRLKKKKTSIKKCTLNPYYNES 362 Query: 403 FDFVV--EDALHDLLMVEVWDHDTFG-KDYIGRCIL 305 F F V E LM+ V D+D G D IGRC+L Sbjct: 363 FSFEVPFEQIQKVSLMITVMDYDKLGSNDAIGRCLL 398
>SY65_DROME (P21521) Synaptotagmin (p65)| Length = 474 Score = 56.6 bits (135), Expect = 6e-08 Identities = 39/113 (34%), Positives = 63/113 (55%), Gaps = 10/113 (8%) Frame = -1 Query: 556 LSVTVISAEDIPAMDVMGKADPFVVLYLX-XXXXXXXXXXXXXTLNPIWNQTFDF---VV 389 L+VTVI AE++PA+D+ G +DP+V +YL TL+P++N+TF F Sbjct: 209 LAVTVIQAEELPALDMGGTSDPYVKVYLLPDKKKKFETKVHRKTLSPVFNETFTFKSLPY 268 Query: 388 EDALHDLLMVEVWDHDTFGK-DYIGR-----CILTLTRAILEGEFQDTYALQG 248 DA++ L+ ++D D F K D IG C + L + I E++D +++G Sbjct: 269 ADAMNKTLVFAIFDFDRFSKHDQIGEVKVPLCTIDLAQTI--EEWRDLVSVEG 319 Score = 47.8 bits (112), Expect = 3e-05 Identities = 34/96 (35%), Positives = 50/96 (52%), Gaps = 6/96 (6%) Frame = -1 Query: 574 VITRGVLSVTVISAEDIPAMDVMGKADPFV---VLYLXXXXXXXXXXXXXXTLNPIWNQT 404 V T G L+V ++ A+++ MDV G +DP+V ++ TLNP +N++ Sbjct: 336 VPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIAIMQNGKRLKKKKTSVKKCTLNPYYNES 395 Query: 403 FDFVV--EDALHDLLMVEVWDHDTFG-KDYIGRCIL 305 F F V E L+V V D+D G + IGRCIL Sbjct: 396 FSFEVPFEQMQKICLVVTVVDYDRIGTSEPIGRCIL 431
>SY65_APLCA (P41823) Synaptotagmin-1 (Synaptotagmin I) (p65)| Length = 428 Score = 53.9 bits (128), Expect = 4e-07 Identities = 39/109 (35%), Positives = 55/109 (50%), Gaps = 4/109 (3%) Frame = -1 Query: 565 RGVLSVTVISAEDIPAMDVMGKADPFVVLYLX-XXXXXXXXXXXXXTLNPIWNQTFDFVV 389 +G LSV VI A D+P MD+ G +DP+V +YL TLNP++N++F F V Sbjct: 167 KGELSVNVIQAADLPGMDMSGTSDPYVKVYLLPDKKKKYETKVHRKTLNPVFNESFTFKV 226 Query: 388 --EDALHDLLMVEVWDHDTFGK-DYIGRCILTLTRAILEGEFQDTYALQ 251 + +L V+D D F K D IG+ + L L +D LQ Sbjct: 227 PYAEVGSKILTFAVYDFDRFSKHDQIGQVQVPLNSIDLGRVVEDWKDLQ 275 Score = 47.4 bits (111), Expect = 4e-05 Identities = 33/96 (34%), Positives = 50/96 (52%), Gaps = 6/96 (6%) Frame = -1 Query: 574 VITRGVLSVTVISAEDIPAMDVMGKADPFVVLYL---XXXXXXXXXXXXXXTLNPIWNQT 404 V T G L+V ++ A+++ MDV G +DP+V + L TLNP +N++ Sbjct: 297 VPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIALLQGTKRLKKKKTTIKKNTLNPYFNES 356 Query: 403 FDFVV--EDALHDLLMVEVWDHDTFG-KDYIGRCIL 305 F F V E L++ V D+D G + IGRC+L Sbjct: 357 FGFEVPFEQIQKVTLIITVVDYDRIGTSEPIGRCVL 392
>SYT7_MOUSE (Q9R0N7) Synaptotagmin-7 (Synaptotagmin VII) (SytVII)| Length = 403 Score = 51.6 bits (122), Expect = 2e-06 Identities = 33/96 (34%), Positives = 49/96 (51%), Gaps = 5/96 (5%) Frame = -1 Query: 556 LSVTVISAEDIPAMDVMGKADPFVVLYLX-XXXXXXXXXXXXXTLNPIWNQTF---DFVV 389 L+V V+ A+++PA D G +DPFV +YL LNP WN+TF F Sbjct: 152 LTVKVMKAQELPAKDFSGTSDPFVKIYLLPDKKHKLETKVKRKNLNPHWNETFLFEGFPY 211 Query: 388 EDALHDLLMVEVWDHDTFGK-DYIGRCILTLTRAIL 284 E + +L ++V D+D F + D IG + L + L Sbjct: 212 EKVVQRVLYLQVLDYDRFSRNDPIGEVSIPLNKVDL 247 Score = 40.8 bits (94), Expect = 0.003 Identities = 26/89 (29%), Positives = 43/89 (48%), Gaps = 6/89 (6%) Frame = -1 Query: 550 VTVISAEDIPAMDVMGKADPFV---VLYLXXXXXXXXXXXXXXTLNPIWNQT--FDFVVE 386 V +I A ++ AMD+ G +DP+V ++Y LNPI+N++ FD E Sbjct: 285 VNIIKARNLKAMDIGGTSDPYVKVWLMYKDKRVEKKKTVTKKRNLNPIFNESFAFDIPTE 344 Query: 385 DALHDLLMVEVWDHDTFGK-DYIGRCILT 302 +++ V D D + D IG+ L+ Sbjct: 345 KLRETTIIITVMDKDKLSRNDVIGKIYLS 373
>SYT7_HUMAN (O43581) Synaptotagmin-7 (Synaptotagmin VII) (SytVII)| Length = 402 Score = 50.4 bits (119), Expect = 4e-06 Identities = 31/96 (32%), Positives = 49/96 (51%), Gaps = 5/96 (5%) Frame = -1 Query: 556 LSVTVISAEDIPAMDVMGKADPFVVLYLX-XXXXXXXXXXXXXTLNPIWNQTF---DFVV 389 L++ ++ A+++PA D G +DPFV +YL LNP WN+TF F Sbjct: 151 LTLKIMKAQELPAKDFSGTSDPFVKIYLLPDKKHKLKTKVKRKNLNPHWNETFLFEGFPY 210 Query: 388 EDALHDLLMVEVWDHDTFGK-DYIGRCILTLTRAIL 284 E + +L ++V D+D F + D IG + L + L Sbjct: 211 EKVVQRILYLQVLDYDRFSRNDPIGEVSIPLNKVDL 246 Score = 38.1 bits (87), Expect = 0.021 Identities = 25/89 (28%), Positives = 42/89 (47%), Gaps = 6/89 (6%) Frame = -1 Query: 550 VTVISAEDIPAMDVMGKADPFV---VLYLXXXXXXXXXXXXXXTLNPIWNQT--FDFVVE 386 V +I A ++ AMD+ G +DP+V ++Y LNP +N++ FD E Sbjct: 284 VNIIKARNLKAMDIGGTSDPYVKVWLMYKDKRVEKKKTVTMKRNLNPNFNESFAFDIPTE 343 Query: 385 DALHDLLMVEVWDHDTFGK-DYIGRCILT 302 +++ V D D + D IG+ L+ Sbjct: 344 KLRETTIIITVMDKDKLSRNDVIGKIYLS 372
>YKH3_SCHPO (Q9UT00) Hypothetical protein PYUK71.03c in chromosome I| Length = 1225 Score = 50.4 bits (119), Expect = 4e-06 Identities = 39/123 (31%), Positives = 59/123 (47%), Gaps = 6/123 (4%) Frame = -1 Query: 562 GVLSVTVISAEDIPAMDVMGKADPFVVLYLXXXXXXXXXXXXXXTLNPIWNQTFDFVVED 383 G ++V VI A D+PA D GK+DPFVV L TLNP +N++F+ + Sbjct: 1037 GEMTVDVIKATDLPAADSNGKSDPFVVFEL-QGEEVYRTKTHKRTLNPTFNESFEVELPC 1095 Query: 382 ALHDLLMVEVWDHDTFGK-DYIGRCILTLTRAILEGEFQDTYAL-----QGAKSGRLNLH 221 + V+D D K D++G C++ +L+ + Q Y + QG R+ L Sbjct: 1096 KQTCNFVANVFDWDFGNKDDHLGSCVIDC--KLLQQQQQTNYEIPLDSKQGVLYLRITLS 1153 Query: 220 FKW 212 KW Sbjct: 1154 PKW 1156
>KPC1_LYTPI (Q25378) Protein kinase C (EC 2.7.11.13)| Length = 658 Score = 50.1 bits (118), Expect = 5e-06 Identities = 36/112 (32%), Positives = 55/112 (49%), Gaps = 5/112 (4%) Frame = -1 Query: 556 LSVTVISAEDIPAMDVMGKADPFVVLYL---XXXXXXXXXXXXXXTLNPIWNQTFDFVVE 386 L VTV A+++ MD G +DPFV L L +LNP W ++FDF +E Sbjct: 164 LQVTVAEAKNLIPMDPNGLSDPFVKLKLIPDQKRETKKKTRTIKGSLNPTWGESFDFNLE 223 Query: 385 DA-LHDLLMVEVWDHDTFGK-DYIGRCILTLTRAILEGEFQDTYALQGAKSG 236 D + L+VEVWD D + D++G ++ +++ Y L G + G Sbjct: 224 DTDRNRRLLVEVWDWDRATRNDFMGALSFGISE-LMKAGVDAWYKLLGQEEG 274
>SY62_DISOM (P24506) Synaptotagmin B (Synaptic vesicle protein O-p65-B)| Length = 439 Score = 50.1 bits (118), Expect = 5e-06 Identities = 35/109 (32%), Positives = 59/109 (54%), Gaps = 4/109 (3%) Frame = -1 Query: 556 LSVTVISAEDIPAMDVMGKADPFV-VLYLXXXXXXXXXXXXXXTLNPIWNQTFDFVV--E 386 L+V +I A ++PA+D+ G +DP+V V L TLNP +N++F F V + Sbjct: 176 LTVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKYETKVQKKTLNPTFNESFVFKVPYQ 235 Query: 385 DALHDLLMVEVWDHDTFGK-DYIGRCILTLTRAILEGEFQDTYALQGAK 242 + LM+ V+D D F K D IG+ + +T+ L + ++ L+ A+ Sbjct: 236 ELGGKTLMMAVYDFDRFSKHDCIGQVTVLMTKVDLGQQLEEWRDLESAE 284 Score = 43.5 bits (101), Expect = 5e-04 Identities = 31/93 (33%), Positives = 48/93 (51%), Gaps = 6/93 (6%) Frame = -1 Query: 574 VITRGVLSVTVISAEDIPAMDVMGKADPFVVLYL---XXXXXXXXXXXXXXTLNPIWNQT 404 V T G L+V ++ A+++ MDV G +DP+V ++L TLNP +N++ Sbjct: 301 VPTAGKLTVCILEAKNLKKMDVGGLSDPYVKIHLLQNGKRLKKKKTTVKKNTLNPYYNES 360 Query: 403 FDFVV--EDALHDLLMVEVWDHDTFGK-DYIGR 314 F F + E + V V D+D GK D IG+ Sbjct: 361 FSFEIPFEQIQKVQVCVTVLDYDKIGKNDAIGK 393
>KPCB_HUMAN (P05771) Protein kinase C beta type (EC 2.7.11.13) (PKC-beta)| (PKC-B) Length = 670 Score = 49.7 bits (117), Expect = 7e-06 Identities = 38/109 (34%), Positives = 56/109 (51%), Gaps = 8/109 (7%) Frame = -1 Query: 571 ITRGVLSVTVISAEDIPAMDVMGKADPFVVLYLX---XXXXXXXXXXXXXTLNPIWNQTF 401 I R VL V V A+++ MD G +DP+V L L +LNP WN+TF Sbjct: 167 IDRDVLIVLVRDAKNLVPMDPNGLSDPYVKLKLIPDPKSESKQKTKTIKCSLNPEWNETF 226 Query: 400 DFVVEDALHD-LLMVEVWDHD-TFGKDYIGRC---ILTLTRAILEGEFQ 269 F ++++ D L VE+WD D T D++G I L +A ++G F+ Sbjct: 227 RFQLKESDKDRRLSVEIWDWDLTSRNDFMGSLSFGISELQKASVDGWFK 275
>OTOF_HUMAN (Q9HC10) Otoferlin (Fer-1-like protein 2)| Length = 1997 Score = 49.3 bits (116), Expect = 9e-06 Identities = 28/92 (30%), Positives = 42/92 (45%) Frame = -1 Query: 601 GYDVNQRKNVITRGVLSVTVISAEDIPAMDVMGKADPFVVLYLXXXXXXXXXXXXXXTLN 422 G N NV+ R V V+ A D+ D+ GKADP++ + L LN Sbjct: 1483 GIPSNDPINVLVR----VYVVRATDLHPADINGKADPYIAIRLGKTDIRDKENYISKQLN 1538 Query: 421 PIWNQTFDFVVEDALHDLLMVEVWDHDTFGKD 326 P++ ++FD + +L V V+D D G D Sbjct: 1539 PVFGKSFDIEASFPMESMLTVAVYDWDLVGTD 1570
>UNC13_CAEEL (P27715) Phorbol ester/diacylglycerol-binding protein unc-13| (Uncoordinated protein 13) Length = 2155 Score = 48.9 bits (115), Expect = 1e-05 Identities = 36/129 (27%), Positives = 58/129 (44%), Gaps = 17/129 (13%) Frame = -1 Query: 556 LSVTVISAEDIPAMDVMGKADPFVVLYLXXXXXXXXXXXXXXTLNPIWNQTFDFVVEDAL 377 +++TV+ A+ + A D GK+DP+V + LNP+WN+ F F ++ Sbjct: 1159 ITLTVLCAQGLIAKDKTGKSDPYVTAQV--GKTKRRTRTIHQELNPVWNEKFHFECHNST 1216 Query: 376 HDLLMVEVWDHDTFGK------------DYIGRCILTLTRAILEGEFQDTYALQ-----G 248 D + V VWD D K D++G+ ++ + L GE Y L+ Sbjct: 1217 -DRIKVRVWDEDNDLKSKLRQKLTRESDDFLGQTVIEV--RTLSGEMDVWYNLEKRTDKS 1273 Query: 247 AKSGRLNLH 221 A SG + LH Sbjct: 1274 AVSGAIRLH 1282
>OTOF_MOUSE (Q9ESF1) Otoferlin (Fer-1-like protein 2)| Length = 1997 Score = 48.9 bits (115), Expect = 1e-05 Identities = 27/92 (29%), Positives = 42/92 (45%) Frame = -1 Query: 601 GYDVNQRKNVITRGVLSVTVISAEDIPAMDVMGKADPFVVLYLXXXXXXXXXXXXXXTLN 422 G N NV+ R + V+ A D+ D+ GKADP++ + L LN Sbjct: 1483 GIPSNDPINVLVR----IYVVRATDLHPADINGKADPYIAIKLGKTDIRDKENYISKQLN 1538 Query: 421 PIWNQTFDFVVEDALHDLLMVEVWDHDTFGKD 326 P++ ++FD + +L V V+D D G D Sbjct: 1539 PVFGKSFDIEASFPMESMLTVAVYDWDLVGTD 1570
>KPCB_MOUSE (P68404) Protein kinase C beta type (EC 2.7.11.13) (PKC-beta)| (PKC-B) Length = 672 Score = 48.9 bits (115), Expect = 1e-05 Identities = 38/109 (34%), Positives = 56/109 (51%), Gaps = 8/109 (7%) Frame = -1 Query: 571 ITRGVLSVTVISAEDIPAMDVMGKADPFVVLYLX---XXXXXXXXXXXXXTLNPIWNQTF 401 I R VL V V A+++ MD G +DP+V L L +LNP WN+TF Sbjct: 167 IDREVLIVVVRDAKNLVPMDPNGLSDPYVKLKLIPDPKSESKQKTKTIKCSLNPEWNETF 226 Query: 400 DFVVEDALHD-LLMVEVWDHD-TFGKDYIGRC---ILTLTRAILEGEFQ 269 F ++++ D L VE+WD D T D++G I L +A ++G F+ Sbjct: 227 RFQLKESDKDRRLSVEIWDWDLTSRNDFMGSLSFGISELQKAGVDGWFK 275
>KPCB_BOVIN (P05126) Protein kinase C beta type (EC 2.7.11.13) (PKC-beta)| (PKC-B) Length = 672 Score = 48.9 bits (115), Expect = 1e-05 Identities = 38/109 (34%), Positives = 56/109 (51%), Gaps = 8/109 (7%) Frame = -1 Query: 571 ITRGVLSVTVISAEDIPAMDVMGKADPFVVLYLX---XXXXXXXXXXXXXTLNPIWNQTF 401 I R VL V V A+++ MD G +DP+V L L +LNP WN+TF Sbjct: 167 IEREVLIVVVRDAKNLVPMDPNGLSDPYVKLKLIPDPKSESKQKTKTIKCSLNPEWNETF 226 Query: 400 DFVVEDALHD-LLMVEVWDHD-TFGKDYIGRC---ILTLTRAILEGEFQ 269 F ++++ D L VE+WD D T D++G I L +A ++G F+ Sbjct: 227 RFQLKESDKDRRLSVEIWDWDLTSRNDFMGSLSFGISELQKAGVDGWFK 275
>KPCB_RAT (P68403) Protein kinase C beta type (EC 2.7.11.13) (PKC-beta)| (PKC-B) Length = 670 Score = 48.9 bits (115), Expect = 1e-05 Identities = 38/109 (34%), Positives = 56/109 (51%), Gaps = 8/109 (7%) Frame = -1 Query: 571 ITRGVLSVTVISAEDIPAMDVMGKADPFVVLYLX---XXXXXXXXXXXXXTLNPIWNQTF 401 I R VL V V A+++ MD G +DP+V L L +LNP WN+TF Sbjct: 167 IDREVLIVVVRDAKNLVPMDPNGLSDPYVKLKLIPDPKSESKQKTKTIKCSLNPEWNETF 226 Query: 400 DFVVEDALHD-LLMVEVWDHD-TFGKDYIGRC---ILTLTRAILEGEFQ 269 F ++++ D L VE+WD D T D++G I L +A ++G F+ Sbjct: 227 RFQLKESDKDRRLSVEIWDWDLTSRNDFMGSLSFGISELQKAGVDGWFK 275
>KPCB_RABIT (P05772) Protein kinase C beta type (EC 2.7.11.13) (PKC-beta)| (PKC-B) Length = 670 Score = 48.9 bits (115), Expect = 1e-05 Identities = 38/109 (34%), Positives = 56/109 (51%), Gaps = 8/109 (7%) Frame = -1 Query: 571 ITRGVLSVTVISAEDIPAMDVMGKADPFVVLYLX---XXXXXXXXXXXXXTLNPIWNQTF 401 I R VL V V A+++ MD G +DP+V L L +LNP WN+TF Sbjct: 167 IDREVLIVVVRDAKNLVPMDPNGLSDPYVKLKLIPDPKSESKQKTKTIKCSLNPEWNETF 226 Query: 400 DFVVEDALHD-LLMVEVWDHD-TFGKDYIGRC---ILTLTRAILEGEFQ 269 F ++++ D L VE+WD D T D++G I L +A ++G F+ Sbjct: 227 RFQLKESDKDRRLSVEIWDWDLTSRNDFMGSLSFGISELQKAGVDGWFK 275
>RASL2_HUMAN (O43374) Ras GTPase-activating protein 4 (RasGAP-activating-like| protein 2) (Calcium-promoted Ras inactivator) Length = 803 Score = 48.5 bits (114), Expect = 2e-05 Identities = 28/107 (26%), Positives = 52/107 (48%), Gaps = 1/107 (0%) Frame = -1 Query: 556 LSVTVISAEDIPAMDVMGKADPFVVLYLXXXXXXXXXXXXXXTLNPIWNQTFDFVVEDAL 377 L +V+ A D+ D G +DPFV + + P WN+TF+F +++ Sbjct: 135 LRCSVLEARDLAPKDRNGTSDPFV--RVRYKGRTRETSIVKKSCYPRWNETFEFELQEGA 192 Query: 376 HDLLMVEVWDHDTFGK-DYIGRCILTLTRAILEGEFQDTYALQGAKS 239 + L VE WD D + D++G+ ++ + R + + + + LQ +S Sbjct: 193 MEALCVEAWDWDLVSRNDFLGKVVIDVQRLRVVQQEEGWFRLQPDQS 239 Score = 33.9 bits (76), Expect = 0.40 Identities = 21/89 (23%), Positives = 39/89 (43%), Gaps = 1/89 (1%) Frame = -1 Query: 565 RGVLSVTVISAEDIPAMDVMGKADPFVVLYLXXXXXXXXXXXXXXTLNPIWNQTFDFVVE 386 R L + ++ +++PA D+ G +DP+ ++ + TL P W + + + Sbjct: 4 RSSLYIRIVEGKNLPAKDITGSSDPYCIVKV-DNEPIIRTATVWKTLCPFWGEEYQVHLP 62 Query: 385 DALHDLLMVEVWDHDTFGK-DYIGRCILT 302 H + V D D + D IG+ LT Sbjct: 63 PTFHAVAFY-VMDEDALSRDDVIGKVCLT 90
>UN13A_HUMAN (Q9UPW8) Unc-13 homolog A (Munc13-1)| Length = 1703 Score = 48.5 bits (114), Expect = 2e-05 Identities = 36/129 (27%), Positives = 57/129 (44%), Gaps = 17/129 (13%) Frame = -1 Query: 556 LSVTVISAEDIPAMDVMGKADPFVVLYLXXXXXXXXXXXXXXTLNPIWNQTFDFVVEDAL 377 +S+TV+ A+ + A D G +DP+V + + LNP+W + F F ++ Sbjct: 678 ISITVVCAQGLQAKDKTGSSDPYVTVQV--GKTKKRTKTIYGNLNPVWEENFHFECHNS- 734 Query: 376 HDLLMVEVWDHDTFGK------------DYIGRCILTLTRAILEGEFQDTYAL-----QG 248 D + V VWD D K D++G+ I+ + L GE Y L + Sbjct: 735 SDRIKVRVWDEDDDIKSRVKQRFKRESDDFLGQTIIEV--RTLSGEMDVWYNLDKRTDKS 792 Query: 247 AKSGRLNLH 221 A SG + LH Sbjct: 793 AVSGAIRLH 801
>SYT2_MOUSE (P46097) Synaptotagmin-2 (Synaptotagmin II) (SytII)| Length = 422 Score = 48.1 bits (113), Expect = 2e-05 Identities = 34/109 (31%), Positives = 55/109 (50%), Gaps = 4/109 (3%) Frame = -1 Query: 556 LSVTVISAEDIPAMDVMGKADPFV-VLYLXXXXXXXXXXXXXXTLNPIWNQTFDFVV--E 386 L+V V+ A ++PA+D+ G +DP+V V L TLNP +N+TF F V + Sbjct: 159 LTVGVLQAAELPALDMGGTSDPYVKVFLLPDKKKKYETKVHRKTLNPAFNETFTFKVPYQ 218 Query: 385 DALHDLLMVEVWDHDTFGK-DYIGRCILTLTRAILEGEFQDTYALQGAK 242 + L++ ++D D F K D IG + + L ++ LQG + Sbjct: 219 ELAGKTLVMAIYDFDRFSKHDIIGEVKVPMNTVDLGQPIEEWRDLQGGE 267 Score = 42.7 bits (99), Expect = 9e-04 Identities = 28/88 (31%), Positives = 46/88 (52%), Gaps = 5/88 (5%) Frame = -1 Query: 574 VITRGVLSVTVISAEDIPAMDVMGKADPFVVLYL---XXXXXXXXXXXXXXTLNPIWNQT 404 V T G L+V ++ A+++ MDV G +DP+V ++L TLNP +N++ Sbjct: 284 VPTAGKLTVCILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNES 343 Query: 403 FDFVV--EDALHDLLMVEVWDHDTFGKD 326 F F + E ++V V D+D GK+ Sbjct: 344 FSFEIPFEQIQKVQVVVTVLDYDKLGKN 371
>SYT2_RAT (P29101) Synaptotagmin-2 (Synaptotagmin II) (SytII)| Length = 422 Score = 47.0 bits (110), Expect = 5e-05 Identities = 34/109 (31%), Positives = 55/109 (50%), Gaps = 4/109 (3%) Frame = -1 Query: 556 LSVTVISAEDIPAMDVMGKADPFV-VLYLXXXXXXXXXXXXXXTLNPIWNQTFDFVV--E 386 L+V V+ A ++PA+D+ G +DP+V V L TLNP +N+TF F V + Sbjct: 159 LTVGVLQAAELPALDMGGTSDPYVKVFLLPDKKKKYETKVHRKTLNPAFNETFTFKVPYQ 218 Query: 385 DALHDLLMVEVWDHDTFGK-DYIGRCILTLTRAILEGEFQDTYALQGAK 242 + L++ ++D D F K D IG + + L ++ LQG + Sbjct: 219 ELGGKTLVMAIYDFDRFSKHDIIGEVKVPMNTVDLGQPIEEWRDLQGGE 267 Score = 42.7 bits (99), Expect = 9e-04 Identities = 28/88 (31%), Positives = 46/88 (52%), Gaps = 5/88 (5%) Frame = -1 Query: 574 VITRGVLSVTVISAEDIPAMDVMGKADPFVVLYL---XXXXXXXXXXXXXXTLNPIWNQT 404 V T G L+V ++ A+++ MDV G +DP+V ++L TLNP +N++ Sbjct: 284 VPTAGKLTVCILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNES 343 Query: 403 FDFVV--EDALHDLLMVEVWDHDTFGKD 326 F F + E ++V V D+D GK+ Sbjct: 344 FSFEIPFEQIQKVQVVVTVLDYDKLGKN 371
>SYT2_HUMAN (Q8N9I0) Synaptotagmin-2 (Synaptotagmin II) (SytII)| Length = 419 Score = 47.0 bits (110), Expect = 5e-05 Identities = 34/109 (31%), Positives = 55/109 (50%), Gaps = 4/109 (3%) Frame = -1 Query: 556 LSVTVISAEDIPAMDVMGKADPFV-VLYLXXXXXXXXXXXXXXTLNPIWNQTFDFVV--E 386 L+V V+ A ++PA+D+ G +DP+V V L TLNP +N+TF F V + Sbjct: 156 LTVGVLQAAELPALDMGGTSDPYVKVFLLPDKKKKYETKVHRKTLNPAFNETFTFKVPYQ 215 Query: 385 DALHDLLMVEVWDHDTFGK-DYIGRCILTLTRAILEGEFQDTYALQGAK 242 + L++ ++D D F K D IG + + L ++ LQG + Sbjct: 216 ELGGKTLVMAIYDFDRFSKHDIIGEVKVPMNTVDLGQPIEEWRDLQGGE 264 Score = 40.0 bits (92), Expect = 0.006 Identities = 27/88 (30%), Positives = 45/88 (51%), Gaps = 5/88 (5%) Frame = -1 Query: 574 VITRGVLSVTVISAEDIPAMDVMGKADPFVVLYL---XXXXXXXXXXXXXXTLNPIWNQT 404 V T G L+V ++ A+++ MDV G +DP+ ++L TLNP +N++ Sbjct: 281 VPTAGKLTVCILEAKNLKKMDVGGLSDPYGKIHLMQNGKRLKKKKTTVKKKTLNPYFNES 340 Query: 403 FDFVV--EDALHDLLMVEVWDHDTFGKD 326 F F + E ++V V D+D GK+ Sbjct: 341 FSFEIPFEQIQKVQVVVTVLDYDKLGKN 368
>SY63_DISOM (P24507) Synaptotagmin C (Synaptic vesicle protein O-p65-C)| Length = 537 Score = 46.6 bits (109), Expect = 6e-05 Identities = 32/88 (36%), Positives = 46/88 (52%), Gaps = 4/88 (4%) Frame = -1 Query: 556 LSVTVISAEDIPAMDVMGKADPFVVLYLX-XXXXXXXXXXXXXTLNPIWNQTFDFVV--E 386 L V ++ A D+PA D G +DP+V +YL TLNPI+N+TF F V Sbjct: 253 LVVKILKALDLPAKDANGFSDPYVKIYLLPDRKKKFQTKVHRKTLNPIFNETFQFNVPFN 312 Query: 385 DALHDLLMVEVWDHDTFGK-DYIGRCIL 305 + + L V+D D F + D IG+ +L Sbjct: 313 ELQNRKLHFSVYDFDRFSRHDLIGQVVL 340 Score = 45.1 bits (105), Expect = 2e-04 Identities = 30/92 (32%), Positives = 47/92 (51%), Gaps = 6/92 (6%) Frame = -1 Query: 568 TRGVLSVTVISAEDIPAMDVMGKADPFVVLYL---XXXXXXXXXXXXXXTLNPIWNQ--T 404 T G L++T+I A ++ AMD+ G +DP+V L TLNP++N+ Sbjct: 381 TAGRLTITIIKATNLKAMDLTGFSDPYVKASLICDERRLKKRKTSIKKNTLNPVYNEALV 440 Query: 403 FDFVVEDALHDLLMVEVWDHDTFG-KDYIGRC 311 FD E+ H +++ V D+D G + IG C Sbjct: 441 FDIPNENMEHVNVIIAVMDYDCIGHNEVIGMC 472
>KPCA_RAT (P05696) Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha)| (PKC-A) Length = 671 Score = 46.2 bits (108), Expect = 8e-05 Identities = 40/141 (28%), Positives = 63/141 (44%), Gaps = 18/141 (12%) Frame = -1 Query: 580 KNVITRGVLSVTVISAEDIPAMDVMGKADPFVVLYLX---XXXXXXXXXXXXXTLNPIWN 410 K +T L VTV A+++ MD G +DP+V L L TLNP WN Sbjct: 164 KAEVTDEKLHVTVRDAKNLIPMDPNGLSDPYVKLKLIPDPKNESKQKTKTIRSTLNPQWN 223 Query: 409 QTFDFVVEDALHD-LLMVEVWDHD-TFGKDYIGRCILTLTRAIL-------------EGE 275 ++F F ++ + D L VE+WD D T D++G ++ + EGE Sbjct: 224 ESFTFKLKPSDKDRRLSVEIWDWDRTTRNDFMGSLSFGVSELMKMPASGWYKLLNQEEGE 283 Query: 274 FQDTYALQGAKSGRLNLHFKW 212 + + +G + G + L K+ Sbjct: 284 YYNVPIPEGDEEGNVELRQKF 304
>KPCA_RABIT (P10102) Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha)| (PKC-A) Length = 671 Score = 46.2 bits (108), Expect = 8e-05 Identities = 40/141 (28%), Positives = 63/141 (44%), Gaps = 18/141 (12%) Frame = -1 Query: 580 KNVITRGVLSVTVISAEDIPAMDVMGKADPFVVLYLX---XXXXXXXXXXXXXTLNPIWN 410 K +T L VTV A+++ MD G +DP+V L L TLNP WN Sbjct: 164 KAEVTDEKLHVTVRDAKNLIPMDPNGLSDPYVKLKLIPDPKNESKQKTKTIRSTLNPQWN 223 Query: 409 QTFDFVVEDALHD-LLMVEVWDHD-TFGKDYIGRCILTLTRAIL-------------EGE 275 ++F F ++ + D L VE+WD D T D++G ++ + EGE Sbjct: 224 ESFTFKLKPSDKDRRLSVEIWDWDRTTRNDFMGSLSFGVSELMKMPASGWYKLLNQEEGE 283 Query: 274 FQDTYALQGAKSGRLNLHFKW 212 + + +G + G + L K+ Sbjct: 284 YYNVPIPEGDEDGNVELRQKF 304
>KPCA_MOUSE (P20444) Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha)| (PKC-A) Length = 671 Score = 46.2 bits (108), Expect = 8e-05 Identities = 39/141 (27%), Positives = 62/141 (43%), Gaps = 18/141 (12%) Frame = -1 Query: 580 KNVITRGVLSVTVISAEDIPAMDVMGKADPFVVLYLX---XXXXXXXXXXXXXTLNPIWN 410 K +T L VTV A+++ MD G +DP+V L L LNP WN Sbjct: 164 KAEVTDEKLHVTVRDAKNLIPMDPNGLSDPYVKLKLIPDPKNESKQKTKTIRSNLNPQWN 223 Query: 409 QTFDFVVEDALHD-LLMVEVWDHD-TFGKDYIGRCILTLTRAIL-------------EGE 275 ++F F ++ + D L VE+WD D T D++G ++ + EGE Sbjct: 224 ESFTFKLKPSDKDRRLSVEIWDWDRTTRNDFMGSLSFGVSELMKMPASGWYKAHNQEEGE 283 Query: 274 FQDTYALQGAKSGRLNLHFKW 212 + + +G + G + L K+ Sbjct: 284 YYNVPIPEGDEEGNMELRQKF 304
>SYT10_PONPY (Q5RCK6) Synaptotagmin-10 (Synaptotagmin X) (SytX)| Length = 523 Score = 46.2 bits (108), Expect = 8e-05 Identities = 32/89 (35%), Positives = 46/89 (51%), Gaps = 4/89 (4%) Frame = -1 Query: 559 VLSVTVISAEDIPAMDVMGKADPFVVLYLX-XXXXXXXXXXXXXTLNPIWNQTFDFVV-- 389 +L V +I A D+PA D G +DP+V +YL TLNP++++TF F V Sbjct: 247 LLVVKIIKALDLPAKDFTGTSDPYVKMYLLPDRKKKFQTRVHRKTLNPLFDETFQFPVAY 306 Query: 388 EDALHDLLMVEVWDHDTFGK-DYIGRCIL 305 + + L V+D D F + D IG IL Sbjct: 307 DQLSNRKLHFSVYDFDRFSRHDMIGEVIL 335 Score = 42.7 bits (99), Expect = 9e-04 Identities = 29/92 (31%), Positives = 45/92 (48%), Gaps = 6/92 (6%) Frame = -1 Query: 568 TRGVLSVTVISAEDIPAMDVMGKADPFVVLYL---XXXXXXXXXXXXXXTLNPIWNQT-- 404 T G +++TVI ++ AMD+ G +DP+V + L TLNP++N+ Sbjct: 376 TAGRMTLTVIKCRNLKAMDITGSSDPYVKVSLMCEGRRLKKRKTTTKKNTLNPVYNEAII 435 Query: 403 FDFVVEDALHDLLMVEVWDHDTFG-KDYIGRC 311 FD E+ L + V D+D G + IG C Sbjct: 436 FDIPPENVDQVSLSIAVMDYDRVGHNEVIGVC 467
>SYT10_HUMAN (Q6XYQ8) Synaptotagmin-10 (Synaptotagmin X) (SytX)| Length = 523 Score = 46.2 bits (108), Expect = 8e-05 Identities = 32/89 (35%), Positives = 46/89 (51%), Gaps = 4/89 (4%) Frame = -1 Query: 559 VLSVTVISAEDIPAMDVMGKADPFVVLYLX-XXXXXXXXXXXXXTLNPIWNQTFDFVV-- 389 +L V +I A D+PA D G +DP+V +YL TLNP++++TF F V Sbjct: 247 LLVVKIIKALDLPAKDFTGTSDPYVKMYLLPDRKKKFQTRVHRKTLNPLFDETFQFPVAY 306 Query: 388 EDALHDLLMVEVWDHDTFGK-DYIGRCIL 305 + + L V+D D F + D IG IL Sbjct: 307 DQLSNRKLHFSVYDFDRFSRHDMIGEVIL 335 Score = 42.7 bits (99), Expect = 9e-04 Identities = 29/92 (31%), Positives = 45/92 (48%), Gaps = 6/92 (6%) Frame = -1 Query: 568 TRGVLSVTVISAEDIPAMDVMGKADPFVVLYL---XXXXXXXXXXXXXXTLNPIWNQT-- 404 T G +++TVI ++ AMD+ G +DP+V + L TLNP++N+ Sbjct: 376 TAGRMTLTVIKCRNLKAMDITGSSDPYVKVSLMCEGRRLKKRKTTTKKNTLNPVYNEAII 435 Query: 403 FDFVVEDALHDLLMVEVWDHDTFG-KDYIGRC 311 FD E+ L + V D+D G + IG C Sbjct: 436 FDIPPENVDQVSLSIAVMDYDRVGHNEVIGVC 467
>ERG1_ORYSA (Q7GC09) Elicitor-responsive protein 1 (Fungal elicitor immediate| early-responsive gene 1 protein) (FIERG1) (17 kDa phloem protein) (RPP17) Length = 159 Score = 46.2 bits (108), Expect = 8e-05 Identities = 31/114 (27%), Positives = 50/114 (43%), Gaps = 7/114 (6%) Frame = -1 Query: 562 GVLSVTVISAEDIPAMDVMG---KADPFVVLYLXXXXXXXXXXXXXXTLNPIWNQTFDFV 392 GVL V ++ A+ + D +G K DP+VV+ NP WN+ F F Sbjct: 5 GVLEVHLVDAKGLTGNDFLGEIGKIDPYVVVQYRSQERKSSVARDQGK-NPSWNEVFKFQ 63 Query: 391 VEDAL---HDLLMVEVWDHDTFGK-DYIGRCILTLTRAILEGEFQDTYALQGAK 242 + L + + DHDTF + D++G + +T I G T+ + +K Sbjct: 64 INSTAATGQHKLFLRLMDHDTFSRDDFLGEATINVTDLISLGMEHGTWEMSESK 117
>SYT3_MOUSE (O35681) Synaptotagmin-3 (Synaptotagmin III) (SytIII)| Length = 587 Score = 45.8 bits (107), Expect = 1e-04 Identities = 32/88 (36%), Positives = 45/88 (51%), Gaps = 4/88 (4%) Frame = -1 Query: 556 LSVTVISAEDIPAMDVMGKADPFVVLYLX-XXXXXXXXXXXXXTLNPIWNQTFDFVV--E 386 L V ++ A D+PA D G +DP+V +YL TLNPI+N+TF F V Sbjct: 313 LVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKKFQTKVHRKTLNPIFNETFQFSVPLA 372 Query: 385 DALHDLLMVEVWDHDTFGK-DYIGRCIL 305 + L V+D D F + D IG+ +L Sbjct: 373 ELAQRKLHFSVYDFDRFSRHDLIGQVVL 400 Score = 41.2 bits (95), Expect = 0.003 Identities = 31/92 (33%), Positives = 44/92 (47%), Gaps = 6/92 (6%) Frame = -1 Query: 568 TRGVLSVTVISAEDIPAMDVMGKADPFVVLYLXX---XXXXXXXXXXXXTLNPIWNQ--T 404 T G L+VT+I A ++ AMD+ G +DP+V L TLNP +N+ Sbjct: 441 TAGRLTVTIIKASNLKAMDLTGFSDPYVKASLISEGRRLKKRKTSIKKNTLNPTYNEALV 500 Query: 403 FDFVVEDALHDLLMVEVWDHDTFG-KDYIGRC 311 FD E + L + V D+D G + IG C Sbjct: 501 FDVAPESVENVGLSIAVVDYDCIGHNEVIGVC 532
>SYT3_RAT (P40748) Synaptotagmin-3 (Synaptotagmin III) (SytIII)| Length = 588 Score = 45.8 bits (107), Expect = 1e-04 Identities = 32/88 (36%), Positives = 45/88 (51%), Gaps = 4/88 (4%) Frame = -1 Query: 556 LSVTVISAEDIPAMDVMGKADPFVVLYLX-XXXXXXXXXXXXXTLNPIWNQTFDFVV--E 386 L V ++ A D+PA D G +DP+V +YL TLNPI+N+TF F V Sbjct: 314 LVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKKFQTKVHRKTLNPIFNETFQFSVPLA 373 Query: 385 DALHDLLMVEVWDHDTFGK-DYIGRCIL 305 + L V+D D F + D IG+ +L Sbjct: 374 ELAQRKLHFSVYDFDRFSRHDLIGQVVL 401 Score = 42.7 bits (99), Expect = 9e-04 Identities = 31/92 (33%), Positives = 45/92 (48%), Gaps = 6/92 (6%) Frame = -1 Query: 568 TRGVLSVTVISAEDIPAMDVMGKADPFVVLYLXX---XXXXXXXXXXXXTLNPIWNQ--T 404 T G+L+VT+I A ++ AMD+ G +DP+V L TLNP +N+ Sbjct: 442 TAGLLTVTIIKASNLKAMDLTGFSDPYVKASLISEGRRLKKRKTSIKKNTLNPTYNEALV 501 Query: 403 FDFVVEDALHDLLMVEVWDHDTFG-KDYIGRC 311 FD E + L + V D+D G + IG C Sbjct: 502 FDVAPESVENVGLSIAVVDYDCIGHNEVIGVC 533
>KPCA_HUMAN (P17252) Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha)| (PKC-A) Length = 671 Score = 45.4 bits (106), Expect = 1e-04 Identities = 38/133 (28%), Positives = 60/133 (45%), Gaps = 18/133 (13%) Frame = -1 Query: 556 LSVTVISAEDIPAMDVMGKADPFVVLYLX---XXXXXXXXXXXXXTLNPIWNQTFDFVVE 386 L VTV A+++ MD G +DP+V L L TLNP WN++F F ++ Sbjct: 172 LHVTVRDAKNLIPMDPNGLSDPYVKLKLIPDPKNESKQKTKTIRSTLNPQWNESFTFKLK 231 Query: 385 DALHD-LLMVEVWDHD-TFGKDYIGRCILTLTRAIL-------------EGEFQDTYALQ 251 + D L VE+WD D T D++G ++ + EGE+ + + Sbjct: 232 PSDKDRRLSVEIWDWDRTTRNDFMGSLSFGVSELMKMPASGWYKLLNQEEGEYYNVPIPE 291 Query: 250 GAKSGRLNLHFKW 212 G + G + L K+ Sbjct: 292 GDEEGNMELRQKF 304
>DYSF_MOUSE (Q9ESD7) Dysferlin (Dystrophy-associated fer-1-like protein)| (Fer-1-like protein 1) Length = 2083 Score = 45.4 bits (106), Expect = 1e-04 Identities = 28/86 (32%), Positives = 43/86 (50%), Gaps = 10/86 (11%) Frame = -1 Query: 535 AEDIPAMDVMGKADPFVVLYLXXXXXXXXXXXXXXTLNPIWNQTFDFVVEDALHD----- 371 A D+PAMD +DP+ ++ TLNP W+QT F + + Sbjct: 1164 ARDLPAMDKDSFSDPYSIV--SFLHQSQKTVVEKNTLNPTWDQTLIFYEIEIFGEPASIA 1221 Query: 370 ----LLMVEVWDHDTFGKD-YIGRCI 308 ++VE++DHDT+G D ++GRCI Sbjct: 1222 EHPPCIVVELYDHDTYGADEFMGRCI 1247 Score = 30.0 bits (66), Expect = 5.8 Identities = 22/95 (23%), Positives = 45/95 (47%), Gaps = 4/95 (4%) Frame = -1 Query: 559 VLSVTVISAEDIPAMDVMGKADPFVVLYLXXXXXXXXXXXXXXTLNPIWNQTFDFVVEDA 380 +L + A ++P + ++DP V L ++NP+WN+ F++ ++ Sbjct: 1 MLCCLLARASNLPNVKKDRRSDP--VASLIFRGVKKRTKVIKNSVNPVWNEGFEWDLKGI 58 Query: 379 LHDL---LMVEVWDHDTFGKD-YIGRCILTLTRAI 287 D L+V V DH+T G++ ++G + L + Sbjct: 59 PLDQSSELLVVVKDHETMGRNRFLGEAKIPLQEVL 93
>SYT3_HUMAN (Q9BQG1) Synaptotagmin-3 (Synaptotagmin III) (SytIII)| Length = 590 Score = 45.4 bits (106), Expect = 1e-04 Identities = 31/88 (35%), Positives = 45/88 (51%), Gaps = 4/88 (4%) Frame = -1 Query: 556 LSVTVISAEDIPAMDVMGKADPFVVLYLX-XXXXXXXXXXXXXTLNPIWNQTFDFVV--E 386 L V ++ A D+PA D G +DP+V +YL TLNP++N+TF F V Sbjct: 316 LVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKKFQTKVHRKTLNPVFNETFQFSVPLA 375 Query: 385 DALHDLLMVEVWDHDTFGK-DYIGRCIL 305 + L V+D D F + D IG+ +L Sbjct: 376 ELAQRKLHFSVYDFDRFSRHDLIGQVVL 403 Score = 41.2 bits (95), Expect = 0.003 Identities = 31/92 (33%), Positives = 44/92 (47%), Gaps = 6/92 (6%) Frame = -1 Query: 568 TRGVLSVTVISAEDIPAMDVMGKADPFVVLYLXX---XXXXXXXXXXXXTLNPIWNQ--T 404 T G L+VT+I A ++ AMD+ G +DP+V L TLNP +N+ Sbjct: 444 TAGRLTVTIIKASNLKAMDLTGFSDPYVKASLISEGRRLKKRKTSIKKNTLNPTYNEALV 503 Query: 403 FDFVVEDALHDLLMVEVWDHDTFG-KDYIGRC 311 FD E + L + V D+D G + IG C Sbjct: 504 FDVAPESVENVGLSIAVVDYDCIGHNEVIGVC 535
>YNI7_YEAST (P48231) Hypothetical 132.5 kDa protein in TOP2-MKT1 intergenic| region Length = 1178 Score = 45.4 bits (106), Expect = 1e-04 Identities = 35/134 (26%), Positives = 62/134 (46%), Gaps = 6/134 (4%) Frame = -1 Query: 595 DVNQRKNVITRGVLSVTVISAEDIPAMDVMGKADPFVVLYLXXXXXX--XXXXXXXXTLN 422 ++ Q + G L +T SAE++ ++ G +DP+V +L TLN Sbjct: 972 ELPQSDLITNSGDLKITAKSAENLIGVNKNGYSDPYVEFFLNEKSTSPFFKTAVQKKTLN 1031 Query: 421 PIWNQTFDFVVEDALHDLLMVEVWDHD-TFGKDYIGRCILTLTRAILEGEFQDTYALQGA 245 P WN++ V + ++D L + V D++ T IG+ ++ L+ E + L G Sbjct: 1032 PTWNESKTIEVSNRVNDYLTINVKDYESTNSNRSIGKAVVPLSTIDPESDTTFNIPLVGP 1091 Query: 244 K---SGRLNLHFKW 212 K G L+L F++ Sbjct: 1092 KGEDGGVLHLEFEF 1105 Score = 33.9 bits (76), Expect = 0.40 Identities = 26/103 (25%), Positives = 44/103 (42%) Frame = -1 Query: 562 GVLSVTVISAEDIPAMDVMGKADPFVVLYLXXXXXXXXXXXXXXTLNPIWNQTFDFVVED 383 G+L V + AE++ D +GK P+ + + LNPIWNQ+ V Sbjct: 650 GMLRVFINKAENLRNPDSLGKISPYAKVSVNGVARGRTNERIET-LNPIWNQSIYVSVTS 708 Query: 382 ALHDLLMVEVWDHDTFGKDYIGRCILTLTRAILEGEFQDTYAL 254 L + ++ + DT G D+ + T+ I + D Y + Sbjct: 709 PLQK-VSIDCFGIDTNGDDHNLGSLNIQTQNIYHKDNDDKYTI 750
>SYT1_CHICK (P47191) Synaptotagmin-1 (Synaptotagmin I) (SytI) (p65)| Length = 424 Score = 45.4 bits (106), Expect = 1e-04 Identities = 32/93 (34%), Positives = 49/93 (52%), Gaps = 6/93 (6%) Frame = -1 Query: 574 VITRGVLSVTVISAEDIPAMDVMGKADPFVVLYL---XXXXXXXXXXXXXXTLNPIWNQT 404 V T G L+V ++ A+++ MDV G +DP+V ++L TLNP +N++ Sbjct: 286 VPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNES 345 Query: 403 FDFVV--EDALHDLLMVEVWDHDTFGK-DYIGR 314 F F V E ++V V D+D GK D IG+ Sbjct: 346 FSFEVPFEQIQKVQIVVTVLDYDKIGKNDAIGK 378 Score = 42.4 bits (98), Expect = 0.001 Identities = 30/84 (35%), Positives = 44/84 (52%), Gaps = 4/84 (4%) Frame = -1 Query: 556 LSVTVISAEDIPAMDVMGKADPFV-VLYLXXXXXXXXXXXXXXTLNPIWNQTFDFVV--E 386 L V +I A ++PA+D+ G +DP+V V L TLNP++N+ F F V Sbjct: 161 LLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKYETKVHRKTLNPVFNEQFTFKVPYS 220 Query: 385 DALHDLLMVEVWDHDTFGK-DYIG 317 + L++ V+D D F K D IG Sbjct: 221 ELGGKTLVMAVYDFDRFSKHDIIG 244
>ITSN2_HUMAN (Q9NZM3) Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18)| (SH3P18-like WASP-associated protein) Length = 1696 Score = 45.1 bits (105), Expect = 2e-04 Identities = 32/115 (27%), Positives = 52/115 (45%), Gaps = 1/115 (0%) Frame = -1 Query: 562 GVLSVTVISAEDIPAMDVMGKADPFVVLYLXXXXXXXXXXXXXXTLNPIWNQTFDFVVED 383 G L V VI A ++ A GK++P+ + + LNP WN F ++D Sbjct: 1568 GRLMVHVIEATELKACKPNGKSNPYCEISMGSQSYTTRTIQDT--LNPKWNFNCQFFIKD 1625 Query: 382 ALHDLLMVEVWDHDTFG-KDYIGRCILTLTRAILEGEFQDTYALQGAKSGRLNLH 221 D+L + ++D D F D++GR + + + E E +G + RL LH Sbjct: 1626 LYQDVLCLTLFDRDQFSPDDFLGRTEIPVAKIRTEQE------SKGPMTRRLLLH 1674
>SY61_DISOM (P24505) Synaptotagmin A (Synaptic vesicle protein O-p65-A)| Length = 427 Score = 45.1 bits (105), Expect = 2e-04 Identities = 32/93 (34%), Positives = 49/93 (52%), Gaps = 6/93 (6%) Frame = -1 Query: 574 VITRGVLSVTVISAEDIPAMDVMGKADPFVVLYL---XXXXXXXXXXXXXXTLNPIWNQT 404 V T G L+V ++ A+++ MDV G +DP+V ++L TLNP +N++ Sbjct: 289 VPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNES 348 Query: 403 FDFVV--EDALHDLLMVEVWDHDTFGK-DYIGR 314 F F V E ++V V D+D GK D IG+ Sbjct: 349 FSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGK 381 Score = 45.1 bits (105), Expect = 2e-04 Identities = 34/109 (31%), Positives = 54/109 (49%), Gaps = 4/109 (3%) Frame = -1 Query: 556 LSVTVISAEDIPAMDVMGKADPFV-VLYLXXXXXXXXXXXXXXTLNPIWNQTFDFVV--E 386 L V +I A ++PA+DV G +DP+V V L TLNP++N++F F + Sbjct: 164 LIVGIIQAAELPALDVGGTSDPYVKVFVLPDKKKKYETKVHRKTLNPVFNESFIFKIPYS 223 Query: 385 DALHDLLMVEVWDHDTFGK-DYIGRCILTLTRAILEGEFQDTYALQGAK 242 + L++ V+D D F K D IG + + ++ LQGA+ Sbjct: 224 ELGGKTLVMAVYDFDRFSKHDVIGEAKVPMNTVDFGHVTEEWRDLQGAE 272
>SYT1_HUMAN (P21579) Synaptotagmin-1 (Synaptotagmin I) (SytI) (p65)| Length = 422 Score = 45.1 bits (105), Expect = 2e-04 Identities = 32/93 (34%), Positives = 49/93 (52%), Gaps = 6/93 (6%) Frame = -1 Query: 574 VITRGVLSVTVISAEDIPAMDVMGKADPFVVLYL---XXXXXXXXXXXXXXTLNPIWNQT 404 V T G L+V ++ A+++ MDV G +DP+V ++L TLNP +N++ Sbjct: 284 VPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNES 343 Query: 403 FDFVV--EDALHDLLMVEVWDHDTFGK-DYIGR 314 F F V E ++V V D+D GK D IG+ Sbjct: 344 FSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGK 376 Score = 42.4 bits (98), Expect = 0.001 Identities = 30/84 (35%), Positives = 44/84 (52%), Gaps = 4/84 (4%) Frame = -1 Query: 556 LSVTVISAEDIPAMDVMGKADPFV-VLYLXXXXXXXXXXXXXXTLNPIWNQTFDFVV--E 386 L V +I A ++PA+D+ G +DP+V V L TLNP++N+ F F V Sbjct: 159 LLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYS 218 Query: 385 DALHDLLMVEVWDHDTFGK-DYIG 317 + L++ V+D D F K D IG Sbjct: 219 ELGGKTLVMAVYDFDRFSKHDIIG 242
>SYT1_BOVIN (P48018) Synaptotagmin-1 (Synaptotagmin I) (SytI) (p65)| Length = 422 Score = 45.1 bits (105), Expect = 2e-04 Identities = 32/93 (34%), Positives = 49/93 (52%), Gaps = 6/93 (6%) Frame = -1 Query: 574 VITRGVLSVTVISAEDIPAMDVMGKADPFVVLYL---XXXXXXXXXXXXXXTLNPIWNQT 404 V T G L+V ++ A+++ MDV G +DP+V ++L TLNP +N++ Sbjct: 284 VPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNES 343 Query: 403 FDFVV--EDALHDLLMVEVWDHDTFGK-DYIGR 314 F F V E ++V V D+D GK D IG+ Sbjct: 344 FSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGK 376 Score = 42.4 bits (98), Expect = 0.001 Identities = 30/84 (35%), Positives = 44/84 (52%), Gaps = 4/84 (4%) Frame = -1 Query: 556 LSVTVISAEDIPAMDVMGKADPFV-VLYLXXXXXXXXXXXXXXTLNPIWNQTFDFVV--E 386 L V +I A ++PA+D+ G +DP+V V L TLNP++N+ F F V Sbjct: 159 LLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYS 218 Query: 385 DALHDLLMVEVWDHDTFGK-DYIG 317 + L++ V+D D F K D IG Sbjct: 219 ELGGKTLVMAVYDFDRFSKHDIIG 242
>UN13C_MOUSE (Q8K0T7) Unc-13 homolog C (Munc13-3) (Fragment)| Length = 1430 Score = 45.1 bits (105), Expect = 2e-04 Identities = 35/128 (27%), Positives = 58/128 (45%), Gaps = 17/128 (13%) Frame = -1 Query: 556 LSVTVISAEDIPAMDVMGKADPFVVLYLXXXXXXXXXXXXXXTLNPIWNQTFDFVVEDAL 377 +++TV+SA+ + A D G +DP+V + + LNP+W++ F F ++ Sbjct: 1218 ITITVVSAQGLQAKDKTGSSDPYVTVQV--GKNKRRTKTIFGNLNPVWDEKFFFECHNST 1275 Query: 376 HDLLMVEVWDHDTFGK------------DYIGRCILTLTRAILEGEFQDTYALQ-----G 248 D + V VWD D K D++G+ I+ + L GE Y L+ Sbjct: 1276 -DRIKVRVWDEDDDIKSRVKQHFKKESDDFLGQTIVEV--RTLSGEMDVWYNLEKRTDKS 1332 Query: 247 AKSGRLNL 224 A SG + L Sbjct: 1333 AVSGAIRL 1340
>UN13C_HUMAN (Q8NB66) Unc-13 homolog C (Munc13-3) (Fragment)| Length = 1190 Score = 45.1 bits (105), Expect = 2e-04 Identities = 35/128 (27%), Positives = 58/128 (45%), Gaps = 17/128 (13%) Frame = -1 Query: 556 LSVTVISAEDIPAMDVMGKADPFVVLYLXXXXXXXXXXXXXXTLNPIWNQTFDFVVEDAL 377 +++TV+SA+ + A D G +DP+V + + LNP+W++ F F ++ Sbjct: 198 ITITVVSAQGLQAKDKTGSSDPYVTVQV--GKNKRRTKTIFGNLNPVWDEKFYFECHNST 255 Query: 376 HDLLMVEVWDHDTFGK------------DYIGRCILTLTRAILEGEFQDTYALQ-----G 248 D + V VWD D K D++G+ I+ + L GE Y L+ Sbjct: 256 -DRIKVRVWDEDDDIKSRVKQHFKKESDDFLGQTIVEV--RTLSGEMDVWYNLEKRTDKS 312 Query: 247 AKSGRLNL 224 A SG + L Sbjct: 313 AVSGAIRL 320
>RP3A_RAT (P47709) Rabphilin-3A (Exophilin-1)| Length = 684 Score = 45.1 bits (105), Expect = 2e-04 Identities = 30/95 (31%), Positives = 43/95 (45%), Gaps = 7/95 (7%) Frame = -1 Query: 556 LSVTVISAEDIPAMDVMGKADPFVVLYL---XXXXXXXXXXXXXXTLNPIWNQTFDF--- 395 L T+I A+ + MD G ADP+V L+L T NP+WN+T + Sbjct: 399 LQCTIIRAKGLKPMDSNGLADPYVKLHLLPGASKSNKLRTKTLRNTRNPVWNETLQYHGI 458 Query: 394 VVEDALHDLLMVEVWDHDTFG-KDYIGRCILTLTR 293 ED L + V D D FG ++IG +L + Sbjct: 459 TEEDMQRKTLRISVCDEDKFGHNEFIGETRFSLKK 493 Score = 44.3 bits (103), Expect = 3e-04 Identities = 37/114 (32%), Positives = 52/114 (45%), Gaps = 14/114 (12%) Frame = -1 Query: 595 DVNQRKNVIT-------RGVLSVTVISAEDIPAMDVMGKADPFVVLYL---XXXXXXXXX 446 D+ +R ++ +G L V +I + AMD G +DPFV L+L Sbjct: 537 DIEERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKT 596 Query: 445 XXXXXTLNPIWNQTF--DFVVEDALHDLLMVEVWDHDTFGK--DYIGRCILTLT 296 TLNP +N+ F D D L + VWD+D GK DYIG C L ++ Sbjct: 597 QIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYD-IGKSNDYIGGCQLGIS 649
>RP3A_MOUSE (P47708) Rabphilin-3A (Exophilin-1)| Length = 681 Score = 45.1 bits (105), Expect = 2e-04 Identities = 30/95 (31%), Positives = 43/95 (45%), Gaps = 7/95 (7%) Frame = -1 Query: 556 LSVTVISAEDIPAMDVMGKADPFVVLYL---XXXXXXXXXXXXXXTLNPIWNQTFDF--- 395 L T+I A+ + MD G ADP+V L+L T NP+WN+T + Sbjct: 396 LQCTIIRAKGLKPMDSNGLADPYVKLHLLPGASKSNKLRTKTLRNTRNPVWNETLQYHGI 455 Query: 394 VVEDALHDLLMVEVWDHDTFG-KDYIGRCILTLTR 293 ED L + V D D FG ++IG +L + Sbjct: 456 TEEDMQRKTLRISVCDEDKFGHNEFIGETRFSLKK 490 Score = 44.3 bits (103), Expect = 3e-04 Identities = 37/114 (32%), Positives = 52/114 (45%), Gaps = 14/114 (12%) Frame = -1 Query: 595 DVNQRKNVIT-------RGVLSVTVISAEDIPAMDVMGKADPFVVLYL---XXXXXXXXX 446 D+ +R ++ +G L V +I + AMD G +DPFV L+L Sbjct: 534 DIEERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKT 593 Query: 445 XXXXXTLNPIWNQTF--DFVVEDALHDLLMVEVWDHDTFGK--DYIGRCILTLT 296 TLNP +N+ F D D L + VWD+D GK DYIG C L ++ Sbjct: 594 QIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYD-IGKSNDYIGGCQLGIS 646
>SYT1_RAT (P21707) Synaptotagmin-1 (Synaptotagmin I) (SytI) (p65)| Length = 421 Score = 45.1 bits (105), Expect = 2e-04 Identities = 32/93 (34%), Positives = 49/93 (52%), Gaps = 6/93 (6%) Frame = -1 Query: 574 VITRGVLSVTVISAEDIPAMDVMGKADPFVVLYL---XXXXXXXXXXXXXXTLNPIWNQT 404 V T G L+V ++ A+++ MDV G +DP+V ++L TLNP +N++ Sbjct: 283 VPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNES 342 Query: 403 FDFVV--EDALHDLLMVEVWDHDTFGK-DYIGR 314 F F V E ++V V D+D GK D IG+ Sbjct: 343 FSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGK 375 Score = 42.4 bits (98), Expect = 0.001 Identities = 30/84 (35%), Positives = 44/84 (52%), Gaps = 4/84 (4%) Frame = -1 Query: 556 LSVTVISAEDIPAMDVMGKADPFV-VLYLXXXXXXXXXXXXXXTLNPIWNQTFDFVV--E 386 L V +I A ++PA+D+ G +DP+V V L TLNP++N+ F F V Sbjct: 158 LLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYS 217 Query: 385 DALHDLLMVEVWDHDTFGK-DYIG 317 + L++ V+D D F K D IG Sbjct: 218 ELGGKTLVMAVYDFDRFSKHDIIG 241
>SYT1_MOUSE (P46096) Synaptotagmin-1 (Synaptotagmin I) (SytI) (p65)| Length = 421 Score = 45.1 bits (105), Expect = 2e-04 Identities = 32/93 (34%), Positives = 49/93 (52%), Gaps = 6/93 (6%) Frame = -1 Query: 574 VITRGVLSVTVISAEDIPAMDVMGKADPFVVLYL---XXXXXXXXXXXXXXTLNPIWNQT 404 V T G L+V ++ A+++ MDV G +DP+V ++L TLNP +N++ Sbjct: 283 VPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNES 342 Query: 403 FDFVV--EDALHDLLMVEVWDHDTFGK-DYIGR 314 F F V E ++V V D+D GK D IG+ Sbjct: 343 FSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGK 375 Score = 42.4 bits (98), Expect = 0.001 Identities = 30/84 (35%), Positives = 44/84 (52%), Gaps = 4/84 (4%) Frame = -1 Query: 556 LSVTVISAEDIPAMDVMGKADPFV-VLYLXXXXXXXXXXXXXXTLNPIWNQTFDFVV--E 386 L V +I A ++PA+D+ G +DP+V V L TLNP++N+ F F V Sbjct: 158 LLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYS 217 Query: 385 DALHDLLMVEVWDHDTFGK-DYIG 317 + L++ V+D D F K D IG Sbjct: 218 ELGGKTLVMAVYDFDRFSKHDIIG 241
>SYT10_RAT (O08625) Synaptotagmin-10 (Synaptotagmin X) (SytX)| Length = 523 Score = 45.1 bits (105), Expect = 2e-04 Identities = 33/89 (37%), Positives = 47/89 (52%), Gaps = 4/89 (4%) Frame = -1 Query: 559 VLSVTVISAEDIPAMDVMGKADPFVVLYLX-XXXXXXXXXXXXXTLNPIWNQTFDF-VVE 386 +L V +I A D+PA D G +DP+V +YL TLNP++++ F F VV Sbjct: 247 LLVVKIIKALDLPAKDFTGTSDPYVKIYLLPDRKKKFQTRVHRKTLNPLFDELFQFPVVY 306 Query: 385 DALHD-LLMVEVWDHDTFGK-DYIGRCIL 305 D L + L ++D D F + D IG IL Sbjct: 307 DQLSNRKLHFSIYDFDRFSRHDMIGEVIL 335 Score = 42.7 bits (99), Expect = 9e-04 Identities = 29/92 (31%), Positives = 45/92 (48%), Gaps = 6/92 (6%) Frame = -1 Query: 568 TRGVLSVTVISAEDIPAMDVMGKADPFVVLYL---XXXXXXXXXXXXXXTLNPIWNQT-- 404 T G +++TVI ++ AMD+ G +DP+V + L TLNP++N+ Sbjct: 376 TAGRMTLTVIKCRNLKAMDITGSSDPYVKVSLMCEGRRLKKRKTTTKKNTLNPVYNEAII 435 Query: 403 FDFVVEDALHDLLMVEVWDHDTFG-KDYIGRC 311 FD E+ L + V D+D G + IG C Sbjct: 436 FDIPPENVDQVSLCIAVMDYDRVGHNEVIGVC 467
>SYT10_MOUSE (Q9R0N4) Synaptotagmin-10 (Synaptotagmin X) (SytX)| Length = 523 Score = 45.1 bits (105), Expect = 2e-04 Identities = 33/89 (37%), Positives = 47/89 (52%), Gaps = 4/89 (4%) Frame = -1 Query: 559 VLSVTVISAEDIPAMDVMGKADPFVVLYLX-XXXXXXXXXXXXXTLNPIWNQTFDF-VVE 386 +L V +I A D+PA D G +DP+V +YL TLNP++++ F F VV Sbjct: 247 LLVVKIIKALDLPAKDFTGTSDPYVKIYLLPDRKKKFQTRVHRKTLNPLFDELFQFPVVY 306 Query: 385 DALHD-LLMVEVWDHDTFGK-DYIGRCIL 305 D L + L ++D D F + D IG IL Sbjct: 307 DQLSNRKLHFSIYDFDRFSRHDMIGEVIL 335 Score = 42.7 bits (99), Expect = 9e-04 Identities = 29/92 (31%), Positives = 45/92 (48%), Gaps = 6/92 (6%) Frame = -1 Query: 568 TRGVLSVTVISAEDIPAMDVMGKADPFVVLYL---XXXXXXXXXXXXXXTLNPIWNQT-- 404 T G +++TVI ++ AMD+ G +DP+V + L TLNP++N+ Sbjct: 376 TAGRMTLTVIKCRNLKAMDITGSSDPYVKVSLMCEGRRLKKRKTTTKKNTLNPVYNEAII 435 Query: 403 FDFVVEDALHDLLMVEVWDHDTFG-KDYIGRC 311 FD E+ L + V D+D G + IG C Sbjct: 436 FDIPPENVDQVSLCIAVMDYDRVGHNEVIGVC 467
>SYT1_PONPY (Q5R4J5) Synaptotagmin-1 (Synaptotagmin I) (SytI)| Length = 419 Score = 45.1 bits (105), Expect = 2e-04 Identities = 32/93 (34%), Positives = 49/93 (52%), Gaps = 6/93 (6%) Frame = -1 Query: 574 VITRGVLSVTVISAEDIPAMDVMGKADPFVVLYL---XXXXXXXXXXXXXXTLNPIWNQT 404 V T G L+V ++ A+++ MDV G +DP+V ++L TLNP +N++ Sbjct: 281 VPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKETTIKKNTLNPYYNES 340 Query: 403 FDFVV--EDALHDLLMVEVWDHDTFGK-DYIGR 314 F F V E ++V V D+D GK D IG+ Sbjct: 341 FSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGK 373 Score = 42.4 bits (98), Expect = 0.001 Identities = 30/84 (35%), Positives = 44/84 (52%), Gaps = 4/84 (4%) Frame = -1 Query: 556 LSVTVISAEDIPAMDVMGKADPFV-VLYLXXXXXXXXXXXXXXTLNPIWNQTFDFVV--E 386 L V +I A ++PA+D+ G +DP+V V L TLNP++N+ F F V Sbjct: 156 LLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYS 215 Query: 385 DALHDLLMVEVWDHDTFGK-DYIG 317 + L++ V+D D F K D IG Sbjct: 216 ELGGKTLVMAVYDFDRFSKHDIIG 239
>SYT1_MACFA (Q60HC0) Synaptotagmin-1 (Synaptotagmin I) (SytI)| Length = 419 Score = 45.1 bits (105), Expect = 2e-04 Identities = 32/93 (34%), Positives = 49/93 (52%), Gaps = 6/93 (6%) Frame = -1 Query: 574 VITRGVLSVTVISAEDIPAMDVMGKADPFVVLYL---XXXXXXXXXXXXXXTLNPIWNQT 404 V T G L+V ++ A+++ MDV G +DP+V ++L TLNP +N++ Sbjct: 281 VPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNES 340 Query: 403 FDFVV--EDALHDLLMVEVWDHDTFGK-DYIGR 314 F F V E ++V V D+D GK D IG+ Sbjct: 341 FSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGK 373 Score = 42.4 bits (98), Expect = 0.001 Identities = 30/84 (35%), Positives = 44/84 (52%), Gaps = 4/84 (4%) Frame = -1 Query: 556 LSVTVISAEDIPAMDVMGKADPFV-VLYLXXXXXXXXXXXXXXTLNPIWNQTFDFVV--E 386 L V +I A ++PA+D+ G +DP+V V L TLNP++N+ F F V Sbjct: 156 LLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYS 215 Query: 385 DALHDLLMVEVWDHDTFGK-DYIG 317 + L++ V+D D F K D IG Sbjct: 216 ELGGKTLVMAVYDFDRFSKHDIIG 239
>UN13C_RAT (Q62770) Unc-13 homolog C (Munc13-3)| Length = 2204 Score = 45.1 bits (105), Expect = 2e-04 Identities = 35/128 (27%), Positives = 58/128 (45%), Gaps = 17/128 (13%) Frame = -1 Query: 556 LSVTVISAEDIPAMDVMGKADPFVVLYLXXXXXXXXXXXXXXTLNPIWNQTFDFVVEDAL 377 +++TV+SA+ + A D G +DP+V + + LNP+W++ F F ++ Sbjct: 1212 ITITVVSAQGLQAKDKTGSSDPYVTVQV--GKNKRRTKTIFGNLNPVWDEKFYFECHNST 1269 Query: 376 HDLLMVEVWDHDTFGK------------DYIGRCILTLTRAILEGEFQDTYALQ-----G 248 D + V VWD D K D++G+ I+ + L GE Y L+ Sbjct: 1270 -DRIKVRVWDEDDDIKSRVKQHFKKESDDFLGQTIVEV--RTLSGEMDVWYNLEKRTDKS 1326 Query: 247 AKSGRLNL 224 A SG + L Sbjct: 1327 AVSGAIRL 1334
>SYT6_HUMAN (Q5T7P8) Synaptotagmin-6 (Synaptotagmin VI) (SytVI)| Length = 510 Score = 44.7 bits (104), Expect = 2e-04 Identities = 31/97 (31%), Positives = 49/97 (50%), Gaps = 6/97 (6%) Frame = -1 Query: 568 TRGVLSVTVISAEDIPAMDVMGKADPFVVLYL---XXXXXXXXXXXXXXTLNPIWNQT-- 404 T G L++TVI ++ AMD+ G +DP+V + L TLNP++N+ Sbjct: 374 TAGRLTLTVIKCRNLKAMDITGYSDPYVKVSLLCDGRRLKKKKTTIKKNTLNPVYNEAII 433 Query: 403 FDFVVEDALHDLLMVEVWDHDTFG-KDYIGRCILTLT 296 FD E+ L++ V D+D G + IG C + +T Sbjct: 434 FDIPPENMDQVSLLISVMDYDRVGHNEIIGVCRVGIT 470 Score = 43.5 bits (101), Expect = 5e-04 Identities = 31/88 (35%), Positives = 44/88 (50%), Gaps = 4/88 (4%) Frame = -1 Query: 556 LSVTVISAEDIPAMDVMGKADPFVVLYLX-XXXXXXXXXXXXXTLNPIWNQTFDFVV--E 386 L V ++ A D+PA D G +DP+V +YL TLNP +++ F F V E Sbjct: 246 LIVRILKAFDLPAKDFCGSSDPYVKIYLLPDRKCKLQTRVHRKTLNPTFDENFHFPVPYE 305 Query: 385 DALHDLLMVEVWDHDTFGK-DYIGRCIL 305 + L + V+D D F + D IG IL Sbjct: 306 ELADRKLHLSVFDFDRFSRHDMIGEVIL 333
>KPCG_RABIT (P10829) Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma)| (PKC-delta) Length = 697 Score = 44.7 bits (104), Expect = 2e-04 Identities = 32/89 (35%), Positives = 44/89 (49%), Gaps = 5/89 (5%) Frame = -1 Query: 568 TRGVLSVTVISAEDIPAMDVMGKADPFVVLYLX---XXXXXXXXXXXXXTLNPIWNQTFD 398 T + VTV A ++ MD G +DP+V L L TLNP+WN+TF Sbjct: 169 TSDEIHVTVGEARNLIPMDPNGLSDPYVKLKLIPDPRNLTKQKTRTVKATLNPVWNETFV 228 Query: 397 FVVEDA-LHDLLMVEVWDHD-TFGKDYIG 317 F ++ + L VEVWD D T D++G Sbjct: 229 FNLKPGDVERRLSVEVWDWDRTSRNDFMG 257
>KPCG_HUMAN (P05129) Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma)| Length = 697 Score = 44.7 bits (104), Expect = 2e-04 Identities = 32/89 (35%), Positives = 44/89 (49%), Gaps = 5/89 (5%) Frame = -1 Query: 568 TRGVLSVTVISAEDIPAMDVMGKADPFVVLYLX---XXXXXXXXXXXXXTLNPIWNQTFD 398 T + VTV A ++ MD G +DP+V L L TLNP+WN+TF Sbjct: 169 TADEIHVTVGEARNLIPMDPNGLSDPYVKLKLIPDPRNLTKQKTRTVKATLNPVWNETFV 228 Query: 397 FVVEDA-LHDLLMVEVWDHD-TFGKDYIG 317 F ++ + L VEVWD D T D++G Sbjct: 229 FNLKPGDVERRLSVEVWDWDRTSRNDFMG 257
>YC31_SCHPO (O14065) Hypothetical protein C962.01 in chromosome III| Length = 1429 Score = 44.7 bits (104), Expect = 2e-04 Identities = 35/128 (27%), Positives = 60/128 (46%), Gaps = 1/128 (0%) Frame = -1 Query: 592 VNQRKNVITRGVLSVTVISAEDIPAMDVMGKADPFVVLYLXXXXXXXXXXXXXXTLNPIW 413 +N ++ I G L + +++P D+ +DPFVVL L LNP+W Sbjct: 1068 LNPMESYINSGSLHFMLQDGQNLPIGDIRS-SDPFVVLKLNGESAFKSKVIKKN-LNPVW 1125 Query: 412 NQTFDFVVEDALHDLLMVEVWDHDTFGK-DYIGRCILTLTRAILEGEFQDTYALQGAKSG 236 N+ D VV++ + D+L + +D D K D +G + L E Q + L +K+G Sbjct: 1126 NEEADIVVQNRVLDVLELVCYDWDMGEKPDVLGTSNIDLLSLEPNVESQQSIKLD-SKTG 1184 Query: 235 RLNLHFKW 212 +N ++ Sbjct: 1185 TINASLRF 1192
>UN13B_HUMAN (O14795) Unc-13 homolog B (Munc13-2) (munc13)| Length = 1591 Score = 44.7 bits (104), Expect = 2e-04 Identities = 34/128 (26%), Positives = 56/128 (43%), Gaps = 17/128 (13%) Frame = -1 Query: 556 LSVTVISAEDIPAMDVMGKADPFVVLYLXXXXXXXXXXXXXXTLNPIWNQTFDFVVEDAL 377 +++TV+ A+ + A D G +DP+V + + LNP+W + F F ++ Sbjct: 602 ITITVVCAQGLQAKDKTGSSDPYVTVQV--SKTKKRTKTIFGNLNPVWEEKFHFECHNS- 658 Query: 376 HDLLMVEVWDHDTFGK------------DYIGRCILTLTRAILEGEFQDTYALQ-----G 248 D + V VWD D K D++G+ I+ + L GE Y L+ Sbjct: 659 SDRIKVRVWDEDDDIKSRVKQRLKRESDDFLGQTIIEV--RTLSGEMDVWYNLEKRTDKS 716 Query: 247 AKSGRLNL 224 A SG + L Sbjct: 717 AVSGAIRL 724
>KPCG_BOVIN (P05128) Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma)| (Fragment) Length = 682 Score = 44.7 bits (104), Expect = 2e-04 Identities = 32/89 (35%), Positives = 44/89 (49%), Gaps = 5/89 (5%) Frame = -1 Query: 568 TRGVLSVTVISAEDIPAMDVMGKADPFVVLYLX---XXXXXXXXXXXXXTLNPIWNQTFD 398 T + VTV A ++ MD G +DP+V L L TLNP+WN+TF Sbjct: 154 TSDEIHVTVGEARNLIPMDPNGLSDPYVKLKLIPDPRNLTKQKTRTVKATLNPVWNETFV 213 Query: 397 FVVEDA-LHDLLMVEVWDHD-TFGKDYIG 317 F ++ + L VEVWD D T D++G Sbjct: 214 FNLKPGDVERRLSVEVWDWDRTSRNDFMG 242
>RP3A_BOVIN (Q06846) Rabphilin-3A (Exophilin-1)| Length = 704 Score = 44.3 bits (103), Expect = 3e-04 Identities = 37/114 (32%), Positives = 52/114 (45%), Gaps = 14/114 (12%) Frame = -1 Query: 595 DVNQRKNVIT-------RGVLSVTVISAEDIPAMDVMGKADPFVVLYL---XXXXXXXXX 446 D+ +R ++ +G L V +I + AMD G +DPFV L+L Sbjct: 557 DIEERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKT 616 Query: 445 XXXXXTLNPIWNQTF--DFVVEDALHDLLMVEVWDHDTFGK--DYIGRCILTLT 296 TLNP +N+ F D D L + VWD+D GK DYIG C L ++ Sbjct: 617 QIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYD-IGKSNDYIGGCQLGIS 669 Score = 43.9 bits (102), Expect = 4e-04 Identities = 31/95 (32%), Positives = 43/95 (45%), Gaps = 7/95 (7%) Frame = -1 Query: 556 LSVTVISAEDIPAMDVMGKADPFVVLYL---XXXXXXXXXXXXXXTLNPIWNQTFDF--- 395 L T+I A+ + MD G ADP+V L+L T NPIWN+T + Sbjct: 419 LHCTIIKAKGLKPMDSNGLADPYVKLHLLPGASKSNKLRTKTLRNTRNPIWNETLVYHGI 478 Query: 394 VVEDALHDLLMVEVWDHDTFG-KDYIGRCILTLTR 293 ED L + V D D FG ++IG +L + Sbjct: 479 TDEDMQRKTLRISVCDEDKFGHNEFIGETRFSLKK 513
>UN13B_RAT (Q62769) Unc-13 homolog B (Munc13-2)| Length = 1622 Score = 44.3 bits (103), Expect = 3e-04 Identities = 34/128 (26%), Positives = 56/128 (43%), Gaps = 17/128 (13%) Frame = -1 Query: 556 LSVTVISAEDIPAMDVMGKADPFVVLYLXXXXXXXXXXXXXXTLNPIWNQTFDFVVEDAL 377 +++TV+ A+ + A D G +DP+V + + LNP+W + F F ++ Sbjct: 615 ITITVVCAQGLQAKDKTGSSDPYVTVQV--GKTKKRTKTIFGNLNPVWEEKFHFECHNS- 671 Query: 376 HDLLMVEVWDHDTFGK------------DYIGRCILTLTRAILEGEFQDTYALQ-----G 248 D + V VWD D K D++G+ I+ + L GE Y L+ Sbjct: 672 SDRIKVRVWDEDDDIKSRVKQRLKRESDDFLGQTIIEV--RTLSGEMDVWYNLEKRTDKS 729 Query: 247 AKSGRLNL 224 A SG + L Sbjct: 730 AVSGAIRL 737
>SYT9_RAT (Q925C0) Synaptotagmin-9 (Synaptotagmin IX) (SytIX) (Synaptotagmin| V) (Synaptotagmin 5) Length = 491 Score = 44.3 bits (103), Expect = 3e-04 Identities = 31/94 (32%), Positives = 47/94 (50%), Gaps = 8/94 (8%) Frame = -1 Query: 568 TRGVLSVTVISAEDIPAMDVMGKADPFVVLYL---XXXXXXXXXXXXXXTLNPIWNQTFD 398 T G L++T+I A ++ AMD+ G +DP+V + L TLNP++N+ Sbjct: 365 TAGRLTITIIKARNLKAMDITGASDPYVKVSLMCDGRRLKKRKTSTKRNTLNPVYNEAIV 424 Query: 397 FVVE----DALHDLLMVEVWDHDTFG-KDYIGRC 311 F V D +H L + V D+D G + IG C Sbjct: 425 FDVPPESIDQIH--LSIAVMDYDRVGHNEVIGVC 456 Score = 37.7 bits (86), Expect = 0.028 Identities = 28/88 (31%), Positives = 43/88 (48%), Gaps = 4/88 (4%) Frame = -1 Query: 556 LSVTVISAEDIPAMDVMGKADPFVVLYLX-XXXXXXXXXXXXXTLNPIWNQTFDFVV--E 386 L V + A ++PA D G +DP+V +YL TLNP++++ F F V Sbjct: 237 LIVKIHKAVNLPAKDFSGTSDPYVKIYLLPDRKTKHQTKVHRKTLNPVFDEVFLFPVHYN 296 Query: 385 DALHDLLMVEVWDHDTFGK-DYIGRCIL 305 D L V+D D F + D IG+ ++ Sbjct: 297 DLEARKLHFSVYDFDRFSRHDLIGQVVV 324
>SYT9_MOUSE (Q9R0N9) Synaptotagmin-9 (Synaptotagmin IX) (SytIX) (Synaptotagmin| V) Length = 491 Score = 44.3 bits (103), Expect = 3e-04 Identities = 31/94 (32%), Positives = 47/94 (50%), Gaps = 8/94 (8%) Frame = -1 Query: 568 TRGVLSVTVISAEDIPAMDVMGKADPFVVLYL---XXXXXXXXXXXXXXTLNPIWNQTFD 398 T G L++T+I A ++ AMD+ G +DP+V + L TLNP++N+ Sbjct: 365 TAGRLTITIIKARNLKAMDITGASDPYVKVSLMCDGRRLKKRKTSTKRNTLNPVYNEAIV 424 Query: 397 FVVE----DALHDLLMVEVWDHDTFG-KDYIGRC 311 F V D +H L + V D+D G + IG C Sbjct: 425 FDVPPESIDQIH--LSIAVMDYDRVGHNEVIGVC 456 Score = 37.7 bits (86), Expect = 0.028 Identities = 28/88 (31%), Positives = 43/88 (48%), Gaps = 4/88 (4%) Frame = -1 Query: 556 LSVTVISAEDIPAMDVMGKADPFVVLYLX-XXXXXXXXXXXXXTLNPIWNQTFDFVV--E 386 L V + A ++PA D G +DP+V +YL TLNP++++ F F V Sbjct: 237 LIVKIHKAVNLPAKDFSGTSDPYVKIYLLPDRKTKHQTKVHRKTLNPVFDEVFLFPVHYN 296 Query: 385 DALHDLLMVEVWDHDTFGK-DYIGRCIL 305 D L V+D D F + D IG+ ++ Sbjct: 297 DLEARKLHFSVYDFDRFSRHDLIGQVVV 324
>SYT9_HUMAN (Q86SS6) Synaptotagmin-9 (Synaptotagmin IX) (SytIX)| Length = 491 Score = 44.3 bits (103), Expect = 3e-04 Identities = 31/94 (32%), Positives = 47/94 (50%), Gaps = 8/94 (8%) Frame = -1 Query: 568 TRGVLSVTVISAEDIPAMDVMGKADPFVVLYL---XXXXXXXXXXXXXXTLNPIWNQTFD 398 T G L++T+I A ++ AMD+ G +DP+V + L TLNP++N+ Sbjct: 365 TAGRLTITIIKARNLKAMDITGASDPYVKVSLMCDGRRLKKRKTSTKRNTLNPVYNEAIV 424 Query: 397 FVVE----DALHDLLMVEVWDHDTFG-KDYIGRC 311 F V D +H L + V D+D G + IG C Sbjct: 425 FDVPPENIDQIH--LSIAVMDYDRVGHNEIIGVC 456 Score = 37.7 bits (86), Expect = 0.028 Identities = 28/88 (31%), Positives = 43/88 (48%), Gaps = 4/88 (4%) Frame = -1 Query: 556 LSVTVISAEDIPAMDVMGKADPFVVLYLX-XXXXXXXXXXXXXTLNPIWNQTFDFVV--E 386 L V + A ++PA D G +DP+V +YL TLNP++++ F F V Sbjct: 237 LIVKIHKAVNLPAKDFSGTSDPYVKIYLLPDRKTKHQTKVHRKTLNPVFDEVFLFPVPYN 296 Query: 385 DALHDLLMVEVWDHDTFGK-DYIGRCIL 305 D L V+D D F + D IG+ ++ Sbjct: 297 DLEARKLHFSVYDFDRFSRHDLIGQVVV 324
>ITSN2_MOUSE (Q9Z0R6) Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3| domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2) Length = 1658 Score = 44.3 bits (103), Expect = 3e-04 Identities = 32/115 (27%), Positives = 52/115 (45%), Gaps = 1/115 (0%) Frame = -1 Query: 562 GVLSVTVISAEDIPAMDVMGKADPFVVLYLXXXXXXXXXXXXXXTLNPIWNQTFDFVVED 383 G L V VI A ++ A GK++P+ + + LNP WN F ++D Sbjct: 1530 GRLMVHVIEATELKACKPNGKSNPYCEVSMGSQSYTTRTLQDT--LNPKWNFNCQFFIKD 1587 Query: 382 ALHDLLMVEVWDHDTFG-KDYIGRCILTLTRAILEGEFQDTYALQGAKSGRLNLH 221 D+L + ++D D F D++GR + + + E E +G + RL LH Sbjct: 1588 LYQDVLCLTMFDRDQFSPDDFLGRTEVPVAKIRTEQE------SKGPTTRRLLLH 1636
>KPCG_RAT (P63319) Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma)| Length = 697 Score = 44.3 bits (103), Expect = 3e-04 Identities = 31/89 (34%), Positives = 44/89 (49%), Gaps = 5/89 (5%) Frame = -1 Query: 568 TRGVLSVTVISAEDIPAMDVMGKADPFVVLYLX---XXXXXXXXXXXXXTLNPIWNQTFD 398 T + +TV A ++ MD G +DP+V L L TLNP+WN+TF Sbjct: 169 TSDEIHITVGEARNLIPMDPNGLSDPYVKLKLIPDPRNLTKQKTKTVKATLNPVWNETFV 228 Query: 397 FVVEDA-LHDLLMVEVWDHD-TFGKDYIG 317 F ++ + L VEVWD D T D++G Sbjct: 229 FNLKPGDVERRLSVEVWDWDRTSRNDFMG 257
>KPCG_MOUSE (P63318) Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma)| Length = 697 Score = 44.3 bits (103), Expect = 3e-04 Identities = 31/89 (34%), Positives = 44/89 (49%), Gaps = 5/89 (5%) Frame = -1 Query: 568 TRGVLSVTVISAEDIPAMDVMGKADPFVVLYLX---XXXXXXXXXXXXXTLNPIWNQTFD 398 T + +TV A ++ MD G +DP+V L L TLNP+WN+TF Sbjct: 169 TSDEIHITVGEARNLIPMDPNGLSDPYVKLKLIPDPRNLTKQKTKTVKATLNPVWNETFV 228 Query: 397 FVVEDA-LHDLLMVEVWDHD-TFGKDYIG 317 F ++ + L VEVWD D T D++G Sbjct: 229 FNLKPGDVERRLSVEVWDWDRTSRNDFMG 257
>UN13B_MOUSE (Q9Z1N9) Unc-13 homolog B (Munc13-2) (munc13)| Length = 1591 Score = 44.3 bits (103), Expect = 3e-04 Identities = 34/128 (26%), Positives = 56/128 (43%), Gaps = 17/128 (13%) Frame = -1 Query: 556 LSVTVISAEDIPAMDVMGKADPFVVLYLXXXXXXXXXXXXXXTLNPIWNQTFDFVVEDAL 377 +++TV+ A+ + A D G +DP+V + + LNP+W + F F ++ Sbjct: 602 ITITVVCAQGLQAKDKTGSSDPYVTVQV--GKTKKRTKTIFGNLNPVWEEKFHFECHNS- 658 Query: 376 HDLLMVEVWDHDTFGK------------DYIGRCILTLTRAILEGEFQDTYALQ-----G 248 D + V VWD D K D++G+ I+ + L GE Y L+ Sbjct: 659 SDRIKVRVWDEDDDIKSRVKQRLKRESDDFLGQTIIEV--RTLSGEMDVWYNLEKRTDKS 716 Query: 247 AKSGRLNL 224 A SG + L Sbjct: 717 AVSGAIRL 724
>RP3A_HUMAN (Q9Y2J0) Rabphilin-3A (Exophilin-1)| Length = 694 Score = 44.3 bits (103), Expect = 3e-04 Identities = 37/114 (32%), Positives = 52/114 (45%), Gaps = 14/114 (12%) Frame = -1 Query: 595 DVNQRKNVIT-------RGVLSVTVISAEDIPAMDVMGKADPFVVLYL---XXXXXXXXX 446 D+ +R ++ +G L V +I + AMD G +DPFV L+L Sbjct: 547 DIEERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKT 606 Query: 445 XXXXXTLNPIWNQTF--DFVVEDALHDLLMVEVWDHDTFGK--DYIGRCILTLT 296 TLNP +N+ F D D L + VWD+D GK DYIG C L ++ Sbjct: 607 QIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYD-IGKSNDYIGGCQLGIS 659 Score = 44.3 bits (103), Expect = 3e-04 Identities = 31/95 (32%), Positives = 43/95 (45%), Gaps = 7/95 (7%) Frame = -1 Query: 556 LSVTVISAEDIPAMDVMGKADPFVVLYL---XXXXXXXXXXXXXXTLNPIWNQTFDF--- 395 L T+I A+ + MD G ADP+V L+L T NPIWN+T + Sbjct: 409 LQCTIIKAKGLKPMDSNGLADPYVKLHLLPGASKSNKLRTKTLRNTRNPIWNETLVYHGI 468 Query: 394 VVEDALHDLLMVEVWDHDTFG-KDYIGRCILTLTR 293 ED L + V D D FG ++IG +L + Sbjct: 469 TDEDMQRKTLRISVCDEDKFGHNEFIGETRFSLKK 503
>PCLO_HUMAN (Q9Y6V0) Protein piccolo (Aczonin)| Length = 5183 Score = 43.9 bits (102), Expect = 4e-04 Identities = 29/96 (30%), Positives = 44/96 (45%), Gaps = 7/96 (7%) Frame = -1 Query: 562 GVLSVTVISAEDIPAMDVMGKADPFVVLYL---XXXXXXXXXXXXXXTLNPIWNQTF--- 401 G L + ++ A ++ D G +DPFV +YL +LNP WNQT Sbjct: 4578 GNLIIHILQARNLVPRDNNGYSDPFVKVYLLPGRGAEYKRRTKHVQKSLNPEWNQTVIYK 4637 Query: 400 DFVVEDALHDLLMVEVWDHDTF-GKDYIGRCILTLT 296 +E L V VWD+D F D++G ++ L+ Sbjct: 4638 SISMEQLKKKTLEVTVWDYDRFSSNDFLGEVLIDLS 4673
>UN13A_RAT (Q62768) Unc-13 homolog A (Munc13-1)| Length = 1735 Score = 43.5 bits (101), Expect = 5e-04 Identities = 35/129 (27%), Positives = 56/129 (43%), Gaps = 17/129 (13%) Frame = -1 Query: 556 LSVTVISAEDIPAMDVMGKADPFVVLYLXXXXXXXXXXXXXXTLNPIWNQTFDFVVEDAL 377 +S+TV+ A+ + A D G +DP+V + + LNP+W + F F ++ Sbjct: 691 ISITVVCAQGLQAKDKTGSSDPYVTVQV--GKTKKRTKTIYGNLNPVWEENFHFECHNS- 747 Query: 376 HDLLMVEVWDHDTFGK------------DYIGRCILTLTRAILEGEFQDTYAL-----QG 248 D + V V D D K D++G+ I+ + L GE Y L + Sbjct: 748 SDRIKVRVLDEDDDIKSRVKQRFKRESDDFLGQTIIEV--RTLSGEMDVWYNLDKRTDKS 805 Query: 247 AKSGRLNLH 221 A SG + LH Sbjct: 806 AVSGAIRLH 814
>SYT6_RAT (Q62746) Synaptotagmin-6 (Synaptotagmin VI) (SytVI)| Length = 511 Score = 43.5 bits (101), Expect = 5e-04 Identities = 30/92 (32%), Positives = 46/92 (50%), Gaps = 6/92 (6%) Frame = -1 Query: 568 TRGVLSVTVISAEDIPAMDVMGKADPFVVLYL---XXXXXXXXXXXXXXTLNPIWNQT-- 404 T G L++TVI ++ AMD+ G +DP+V + L TLNP++N+ Sbjct: 375 TAGRLTLTVIKCRNLKAMDITGYSDPYVKVSLLCDGRRLKKKKTTIKKNTLNPVYNEAII 434 Query: 403 FDFVVEDALHDLLMVEVWDHDTFG-KDYIGRC 311 FD E+ L++ V D+D G + IG C Sbjct: 435 FDIPPENMDQVSLLISVMDYDRVGHNEIIGVC 466 Score = 43.5 bits (101), Expect = 5e-04 Identities = 31/88 (35%), Positives = 44/88 (50%), Gaps = 4/88 (4%) Frame = -1 Query: 556 LSVTVISAEDIPAMDVMGKADPFVVLYLX-XXXXXXXXXXXXXTLNPIWNQTFDFVV--E 386 L V ++ A D+PA D G +DP+V +YL TLNP +++ F F V E Sbjct: 247 LIVRILKAFDLPAKDFCGSSDPYVKIYLLPDRKCKLQTRVHRKTLNPTFDENFHFPVPYE 306 Query: 385 DALHDLLMVEVWDHDTFGK-DYIGRCIL 305 + L + V+D D F + D IG IL Sbjct: 307 ELADRKLHLSVFDFDRFSRHDMIGEVIL 334
>SYT6_MOUSE (Q9R0N8) Synaptotagmin-6 (Synaptotagmin VI) (SytVI)| Length = 511 Score = 43.5 bits (101), Expect = 5e-04 Identities = 30/92 (32%), Positives = 46/92 (50%), Gaps = 6/92 (6%) Frame = -1 Query: 568 TRGVLSVTVISAEDIPAMDVMGKADPFVVLYL---XXXXXXXXXXXXXXTLNPIWNQT-- 404 T G L++TVI ++ AMD+ G +DP+V + L TLNP++N+ Sbjct: 375 TAGRLTLTVIKCRNLKAMDITGYSDPYVKVSLLCDGRRLKKKKTTIKKNTLNPVYNEAII 434 Query: 403 FDFVVEDALHDLLMVEVWDHDTFG-KDYIGRC 311 FD E+ L++ V D+D G + IG C Sbjct: 435 FDIPPENMDQVSLLISVMDYDRVGHNEIIGVC 466 Score = 43.5 bits (101), Expect = 5e-04 Identities = 31/88 (35%), Positives = 44/88 (50%), Gaps = 4/88 (4%) Frame = -1 Query: 556 LSVTVISAEDIPAMDVMGKADPFVVLYLX-XXXXXXXXXXXXXTLNPIWNQTFDFVV--E 386 L V ++ A D+PA D G +DP+V +YL TLNP +++ F F V E Sbjct: 247 LIVRILKAFDLPAKDFCGSSDPYVKIYLLPDRKCKLQTRVHRKTLNPTFDENFHFPVPYE 306 Query: 385 DALHDLLMVEVWDHDTFGK-DYIGRCIL 305 + L + V+D D F + D IG IL Sbjct: 307 ELADRKLHLSVFDFDRFSRHDMIGEVIL 334
>DYSF_HUMAN (O75923) Dysferlin (Dystrophy-associated fer-1-like protein)| (Fer-1-like protein 1) Length = 2080 Score = 42.7 bits (99), Expect = 9e-04 Identities = 27/86 (31%), Positives = 42/86 (48%), Gaps = 10/86 (11%) Frame = -1 Query: 535 AEDIPAMDVMGKADPFVVLYLXXXXXXXXXXXXXXTLNPIWNQTFDFVVEDALHD----- 371 A D+ AMD +DP+ ++ TLNP W+QT F + + Sbjct: 1161 ARDLAAMDKDSFSDPYAIV--SFLHQSQKTVVVKNTLNPTWDQTLIFYEIEIFGEPATVA 1218 Query: 370 ----LLMVEVWDHDTFGKD-YIGRCI 308 ++VE++DHDT+G D ++GRCI Sbjct: 1219 EQPPSIVVELYDHDTYGADEFMGRCI 1244
>NED4L_PONPY (Q5RBF2) E3 ubiquitin-protein ligase NEDD4-like protein (EC| 6.3.2.-) Length = 959 Score = 42.7 bits (99), Expect = 9e-04 Identities = 30/94 (31%), Positives = 46/94 (48%), Gaps = 6/94 (6%) Frame = -1 Query: 559 VLSVTVISAEDIPAMDVMGKADPFVVLYLXXXX-----XXXXXXXXXXTLNPIWNQTFDF 395 +L V V+S D+ D+ G +DP+V L L TLNP WN+ F F Sbjct: 25 ILRVKVVSGIDLAKKDIFGASDPYVKLSLYVADENRELALVQTKTIKKTLNPKWNEEFYF 84 Query: 394 VVEDALHDLLMVEVWDHDTFGK-DYIGRCILTLT 296 V + H LL EV+D + + D++G+ + L+ Sbjct: 85 RVNPSNHRLLF-EVFDENRLTRDDFLGQVDVPLS 117
>NED4L_MOUSE (Q8CFI0) E3 ubiquitin-protein ligase NEDD4-like protein (EC| 6.3.2.-) (Nedd4-2) (NEDD4.2) Length = 1004 Score = 42.7 bits (99), Expect = 9e-04 Identities = 30/94 (31%), Positives = 46/94 (48%), Gaps = 6/94 (6%) Frame = -1 Query: 559 VLSVTVISAEDIPAMDVMGKADPFVVLYLXXXX-----XXXXXXXXXXTLNPIWNQTFDF 395 +L V V+S D+ D+ G +DP+V L L TLNP WN+ F F Sbjct: 49 ILRVKVVSGIDLAKKDIFGASDPYVKLSLYVADENRELALVQTKTIKKTLNPKWNEEFYF 108 Query: 394 VVEDALHDLLMVEVWDHDTFGK-DYIGRCILTLT 296 V + H LL EV+D + + D++G+ + L+ Sbjct: 109 RVNPSNHRLLF-EVFDENRLTRDDFLGQVDVPLS 141
>RBF1_CAEEL (P41885) Rabphilin-1| Length = 1106 Score = 42.7 bits (99), Expect = 9e-04 Identities = 27/94 (28%), Positives = 43/94 (45%), Gaps = 6/94 (6%) Frame = -1 Query: 556 LSVTVISAEDIPAMDVMGKADPFVVLYL---XXXXXXXXXXXXXXTLNPIWNQTFDF--- 395 L + +I A+++ AMD G +DP+V +L TLNP WN+ + Sbjct: 844 LKMHLIRAKNLKAMDSNGFSDPYVKFHLLPGNTKATKLTSKTIEKTLNPEWNEEMSYYGI 903 Query: 394 VVEDALHDLLMVEVWDHDTFGKDYIGRCILTLTR 293 +D +L V V D D G D++G + L + Sbjct: 904 TEDDKEKKILRVTVLDRDRIGSDFLGETRIALKK 937 Score = 41.6 bits (96), Expect = 0.002 Identities = 31/97 (31%), Positives = 45/97 (46%), Gaps = 7/97 (7%) Frame = -1 Query: 571 ITRGVLSVTVISAEDIPAMDVMGKADPFVVLYLXXXXXXXXXXXXXX---TLNPIWNQTF 401 I +G L + + ++ MD G +DP+ + L TLNP WN+ Sbjct: 979 IQQGSLFININRCVELVGMDSTGFSDPYCKVSLTPITSKAHRAKTSTKKRTLNPEWNEQL 1038 Query: 400 DFVV--EDALHDLLMVEVWDHDTFGK--DYIGRCILT 302 FVV +D L + V+DHD GK DYIG +L+ Sbjct: 1039 QFVVPFKDLPKKTLQIGVYDHD-LGKHDDYIGGILLS 1074
>PCLO_RAT (Q9JKS6) Protein piccolo (Aczonin) (Multidomain presynaptic| cytomatrix protein) Length = 5085 Score = 42.7 bits (99), Expect = 9e-04 Identities = 29/105 (27%), Positives = 45/105 (42%), Gaps = 16/105 (15%) Frame = -1 Query: 562 GVLSVTVISAEDIPAMDVMGKADPFVVLYL------------XXXXXXXXXXXXXXTLNP 419 G L + ++ A ++ D G +DPFV +YL +LNP Sbjct: 4652 GNLIIHILQARNLVPRDNNGYSDPFVKVYLLPGRGQVMVVQNASAEYKRRTKYVQKSLNP 4711 Query: 418 IWNQTF---DFVVEDALHDLLMVEVWDHDTF-GKDYIGRCILTLT 296 WNQT +E + L V VWD+D F D++G ++ L+ Sbjct: 4712 EWNQTVIYKSISMEQLMKKTLEVTVWDYDRFSSNDFLGEVLIDLS 4756
>NED4L_HUMAN (Q96PU5) E3 ubiquitin-protein ligase NEDD4-like protein (EC| 6.3.2.-) (Nedd4-2) (NEDD4.2) Length = 975 Score = 42.7 bits (99), Expect = 9e-04 Identities = 30/94 (31%), Positives = 46/94 (48%), Gaps = 6/94 (6%) Frame = -1 Query: 559 VLSVTVISAEDIPAMDVMGKADPFVVLYLXXXX-----XXXXXXXXXXTLNPIWNQTFDF 395 +L V V+S D+ D+ G +DP+V L L TLNP WN+ F F Sbjct: 21 ILRVKVVSGIDLAKKDIFGASDPYVKLSLYVADENRELALVQTKTIKKTLNPKWNEEFYF 80 Query: 394 VVEDALHDLLMVEVWDHDTFGK-DYIGRCILTLT 296 V + H LL EV+D + + D++G+ + L+ Sbjct: 81 RVNPSNHRLLF-EVFDENRLTRDDFLGQVDVPLS 113
>PCLO_MOUSE (Q9QYX7) Protein piccolo (Aczonin) (Multidomain presynaptic| cytomatrix protein) (Brain-derived HLMN protein) Length = 5038 Score = 42.4 bits (98), Expect = 0.001 Identities = 29/105 (27%), Positives = 45/105 (42%), Gaps = 16/105 (15%) Frame = -1 Query: 562 GVLSVTVISAEDIPAMDVMGKADPFVVLYL------------XXXXXXXXXXXXXXTLNP 419 G L + ++ A ++ D G +DPFV +YL +LNP Sbjct: 4605 GNLIIHILQARNLVPRDNNGYSDPFVKVYLLPGRGQVMVVQNASVEYKRRTKYVQKSLNP 4664 Query: 418 IWNQTF---DFVVEDALHDLLMVEVWDHDTF-GKDYIGRCILTLT 296 WNQT +E + L V VWD+D F D++G ++ L+ Sbjct: 4665 EWNQTVIYKSISMEQLMKKTLEVTVWDYDRFSSNDFLGEVLIDLS 4709
>SYT5_RAT (P47861) Synaptotagmin-5 (Synaptotagmin V) (SytV) (Synaptotagmin| IX) Length = 386 Score = 42.4 bits (98), Expect = 0.001 Identities = 33/93 (35%), Positives = 47/93 (50%), Gaps = 6/93 (6%) Frame = -1 Query: 574 VITRGVLSVTVISAEDIPAMDVMGKADPFVVLYL---XXXXXXXXXXXXXXTLNPIWNQT 404 V T G L+V V+ A+++ MDV G +DP+V ++L TLNP +N+ Sbjct: 250 VPTAGKLTVIVLEAKNLKKMDVGGLSDPYVKVHLLQGGKKVRKKKTTIKKNTLNPYYNEA 309 Query: 403 FDFVVEDALHDLLMVE--VWDHDTFGK-DYIGR 314 F F V + VE V D+D GK + IGR Sbjct: 310 FSFEVPCDQVQKVQVELTVLDYDKLGKNEAIGR 342 Score = 39.3 bits (90), Expect = 0.010 Identities = 34/110 (30%), Positives = 53/110 (48%), Gaps = 4/110 (3%) Frame = -1 Query: 562 GVLSVTVISAEDIPAMDVMGKADPFVVLYLX-XXXXXXXXXXXXXTLNPIWNQTFDFVVE 386 G L V ++ AE + A+D+ G +DP+V +YL TLNP + +TF F V Sbjct: 123 GQLLVGILQAEGLAALDLGGSSDPYVSVYLLPDKRRRHETKVHRQTLNPHFGETFAFKVP 182 Query: 385 --DALHDLLMVEVWDHDTFGK-DYIGRCILTLTRAILEGEFQDTYALQGA 245 + +L++ V+D D F + D IG + ++ L Q LQ A Sbjct: 183 YVELGGRVLVMAVYDFDRFSRNDAIGEVRVPMSSVNLGRPVQAWRELQVA 232
>SYT5_MOUSE (Q9R0N5) Synaptotagmin-5 (Synaptotagmin V) (SytV) (Synaptotagmin| IX) Length = 386 Score = 42.4 bits (98), Expect = 0.001 Identities = 33/93 (35%), Positives = 47/93 (50%), Gaps = 6/93 (6%) Frame = -1 Query: 574 VITRGVLSVTVISAEDIPAMDVMGKADPFVVLYL---XXXXXXXXXXXXXXTLNPIWNQT 404 V T G L+V V+ A+++ MDV G +DP+V ++L TLNP +N+ Sbjct: 250 VPTAGKLTVIVLEAKNLKKMDVGGLSDPYVKVHLLQGGKKVRKKKTTIKKNTLNPYYNEA 309 Query: 403 FDFVVEDALHDLLMVE--VWDHDTFGK-DYIGR 314 F F V + VE V D+D GK + IGR Sbjct: 310 FSFEVPCDQVQKVQVELTVLDYDKLGKNEAIGR 342 Score = 38.1 bits (87), Expect = 0.021 Identities = 33/110 (30%), Positives = 53/110 (48%), Gaps = 4/110 (3%) Frame = -1 Query: 562 GVLSVTVISAEDIPAMDVMGKADPFVVLYLX-XXXXXXXXXXXXXTLNPIWNQTFDFVVE 386 G L V ++ A+ + A+D+ G +DP+V +YL TLNP + +TF F V Sbjct: 123 GQLLVGILQAQGLAALDLGGSSDPYVSVYLLPDKRRRHETKVHRQTLNPHFGETFAFKVP 182 Query: 385 --DALHDLLMVEVWDHDTFGK-DYIGRCILTLTRAILEGEFQDTYALQGA 245 + +L++ V+D D F + D IG + ++ L Q LQ A Sbjct: 183 YVELGGRVLVMAVYDFDRFSRNDAIGEVRVPMSSVNLGRPVQAWRELQVA 232
>SYT5_HUMAN (O00445) Synaptotagmin-5 (Synaptotagmin V) (SytV)| Length = 386 Score = 42.4 bits (98), Expect = 0.001 Identities = 33/93 (35%), Positives = 47/93 (50%), Gaps = 6/93 (6%) Frame = -1 Query: 574 VITRGVLSVTVISAEDIPAMDVMGKADPFVVLYL---XXXXXXXXXXXXXXTLNPIWNQT 404 V T G L+V V+ A+++ MDV G +DP+V ++L TLNP +N+ Sbjct: 250 VPTAGKLTVIVLEAKNLKKMDVGGLSDPYVKVHLLQGGKKVRKKKTTIKKNTLNPYYNEA 309 Query: 403 FDFVVEDALHDLLMVE--VWDHDTFGK-DYIGR 314 F F V + VE V D+D GK + IGR Sbjct: 310 FSFEVPCDQVQKVQVELTVLDYDKLGKNEAIGR 342 Score = 37.4 bits (85), Expect = 0.037 Identities = 33/110 (30%), Positives = 52/110 (47%), Gaps = 4/110 (3%) Frame = -1 Query: 562 GVLSVTVISAEDIPAMDVMGKADPFVVLYLX-XXXXXXXXXXXXXTLNPIWNQTFDFVVE 386 G L V ++ A + A+D+ G +DP+V +YL TLNP + +TF F V Sbjct: 123 GQLLVGILQAMGLAALDLGGSSDPYVRVYLLPDKRRRYETKVHRQTLNPHFGETFAFKVP 182 Query: 385 --DALHDLLMVEVWDHDTFGK-DYIGRCILTLTRAILEGEFQDTYALQGA 245 + +L++ V+D D F + D IG + ++ L Q LQ A Sbjct: 183 YVELGGRVLVMAVYDFDRFSRNDAIGEVRVPMSSVDLGRPVQAWRELQAA 232
>KPCA_BOVIN (P04409) Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha)| (PKC-A) Length = 671 Score = 42.0 bits (97), Expect = 0.001 Identities = 38/141 (26%), Positives = 62/141 (43%), Gaps = 18/141 (12%) Frame = -1 Query: 580 KNVITRGVLSVTVISAEDIPAMDVMGKADPFVVLYLX---XXXXXXXXXXXXXTLNPIWN 410 K +T L VTV A+++ MD G +DP+V L L TLNP W+ Sbjct: 164 KAEVTDEKLHVTVRDAKNLIPMDPNGLSDPYVKLKLIPDPKNESKQKTKTIRSTLNPRWD 223 Query: 409 QTFDFVVEDALHD-LLMVEVWDHD-TFGKDYIGRCILTLTRAIL-------------EGE 275 ++F F ++ + D L E+WD D T D++G ++ + EGE Sbjct: 224 ESFTFKLKPSDKDRRLSEEIWDWDRTTRNDFMGSLSFGVSELMKMPASGWYKLLNQEEGE 283 Query: 274 FQDTYALQGAKSGRLNLHFKW 212 + + +G + G + L K+ Sbjct: 284 YYNVPIPEGDEEGNVELRQKF 304
>KPC1_APLCA (Q16974) Calcium-dependent protein kinase C (EC 2.7.11.13) (APL I)| Length = 649 Score = 41.6 bits (96), Expect = 0.002 Identities = 34/113 (30%), Positives = 54/113 (47%), Gaps = 9/113 (7%) Frame = -1 Query: 580 KNVITRGVLSVTVISAEDIPAMDVMGKADPFVVLYLX---XXXXXXXXXXXXXTLNPIWN 410 K + + V ++ A+++ MD G ADP+V + L +LNP+WN Sbjct: 149 KGAVKGSKVLVEILEAKNLCPMDPNGLADPYVKVKLIPYDAHKLKLKTKTIKASLNPVWN 208 Query: 409 QTF--DFVVEDALHDLLMVEVWDHD-TFGKDYIGRC---ILTLTRAILEGEFQ 269 ++F D ED L +EVWD D T D++G I L ++ +EG F+ Sbjct: 209 ESFTVDIGPEDN-SKRLSLEVWDWDRTSRNDFMGSLSFGISELIKSPVEGWFK 260
>PCLO_CHICK (Q9PU36) Protein piccolo (Aczonin) (Fragment)| Length = 5120 Score = 41.6 bits (96), Expect = 0.002 Identities = 29/105 (27%), Positives = 44/105 (41%), Gaps = 16/105 (15%) Frame = -1 Query: 562 GVLSVTVISAEDIPAMDVMGKADPFVVLYL------------XXXXXXXXXXXXXXTLNP 419 G L + ++ A ++ D G +DPFV +YL +LNP Sbjct: 4626 GNLIIHILQARNLAPRDNNGYSDPFVKVYLLPGRGQVMVVQNASAEYKRRTKYVQKSLNP 4685 Query: 418 IWNQTF---DFVVEDALHDLLMVEVWDHDTF-GKDYIGRCILTLT 296 WNQT + E L V VWD+D F D++G ++ L+ Sbjct: 4686 EWNQTVIYKNISTEQLKKKTLEVTVWDYDRFSSNDFLGEVLIDLS 4730
>RSP5_YEAST (P39940) E3 ubiquitin--protein ligase RSP5 (EC 6.3.2.-)| Length = 809 Score = 41.6 bits (96), Expect = 0.002 Identities = 25/78 (32%), Positives = 39/78 (50%), Gaps = 2/78 (2%) Frame = -1 Query: 556 LSVTVISAEDIPAMDVMGKADPFVVLYLXXXXXXXXXXXXXXTLNPIWNQTFDFVVEDAL 377 +SV +++AE + DV DPF VL + LNP WN+TF F D + Sbjct: 5 ISVKLVAAESLYKRDVFRSPDPFAVLTIDGYQTKSTSAAKKT-LNPYWNETFKF---DDI 60 Query: 376 HD--LLMVEVWDHDTFGK 329 ++ +L ++V+D F K Sbjct: 61 NENSILTIQVFDQKKFKK 78
>KPC2_CAEEL (P90980) Protein kinase C-like 2 (EC 2.7.11.13) (PKC2)| Length = 682 Score = 40.8 bits (94), Expect = 0.003 Identities = 32/113 (28%), Positives = 51/113 (45%), Gaps = 6/113 (5%) Frame = -1 Query: 556 LSVTVISAEDIPAMDVMGKADPFVVLYL----XXXXXXXXXXXXXXTLNPIWNQTFDFVV 389 L++ ++ A+++ MD G +DP+V L TLNP WN+TF + + Sbjct: 175 LTIKILEAKNLIPMDPNGLSDPYVKCKLIPEDSGCKSKQKTKTLRATLNPQWNETFTYKL 234 Query: 388 EDALHD-LLMVEVWDHD-TFGKDYIGRCILTLTRAILEGEFQDTYALQGAKSG 236 D L +EVWD D T D++G ++ + E Y L A+ G Sbjct: 235 LPGDKDRRLSIEVWDWDRTSRNDFMGSLSFGISELMKEAA-SGWYKLLSAEEG 286
>DOC2B_HUMAN (Q14184) Double C2-like domain-containing protein beta (Doc2-beta)| Length = 412 Score = 40.8 bits (94), Expect = 0.003 Identities = 29/95 (30%), Positives = 42/95 (44%), Gaps = 7/95 (7%) Frame = -1 Query: 556 LSVTVISAEDIPAMDVMGKADPFVVLYL---XXXXXXXXXXXXXXTLNPIWNQT---FDF 395 L T+ A+ + MD G ADP+V L+L TLNP WN+T + Sbjct: 143 LHCTITKAKGLKPMDHNGLADPYVKLHLLPGASKANKLRTKTLRNTLNPTWNETLTYYGI 202 Query: 394 VVEDALHDLLMVEVWDHDTF-GKDYIGRCILTLTR 293 ED + L + V D D F ++IG + L + Sbjct: 203 TDEDMIRKTLRISVCDEDKFRHNEFIGETRVPLKK 237 Score = 38.9 bits (89), Expect = 0.013 Identities = 30/91 (32%), Positives = 43/91 (47%), Gaps = 7/91 (7%) Frame = -1 Query: 556 LSVTVISAEDIPAMDVMGKADPFVVLYL---XXXXXXXXXXXXXXTLNPIWNQTFDFVVE 386 L V ++ + AMD G +DP+V YL TLNP +N+ F + ++ Sbjct: 283 LLVGIVRCAHLAAMDANGYSDPYVKTYLRPDVDKKSKHKTAVKKKTLNPEFNEEFCYEIK 342 Query: 385 --DALHDLLMVEVWDHDTFGK--DYIGRCIL 305 D L V VWD+D GK D+IG +L Sbjct: 343 HGDLAKKSLEVTVWDYD-IGKSNDFIGGVVL 372
>KPC2_DROME (P13677) Protein kinase C, eye isozyme (EC 2.7.11.13) (PKC)| (dPKC53E(EY)) (Protein INAC) (Inactivation no after-potential C protein) (Photoreceptor-specific PKC) (Eye-PKC) Length = 700 Score = 40.8 bits (94), Expect = 0.003 Identities = 25/85 (29%), Positives = 42/85 (49%), Gaps = 5/85 (5%) Frame = -1 Query: 556 LSVTVISAEDIPAMDVMGKADPFVVLYLX---XXXXXXXXXXXXXTLNPIWNQTFDFVVE 386 L V + A ++ MD G +DP++ + + LNP++N+TF F ++ Sbjct: 208 LKVDIKEAANLIPMDTNGFSDPYIAVQMHPDRSGRTKKKTKTIQKNLNPVFNETFTFELQ 267 Query: 385 DALHD-LLMVEVWDHD-TFGKDYIG 317 D L++EVWD D T D++G Sbjct: 268 PQDRDKRLLIEVWDWDRTSRNDFMG 292
>NEDD4_DROME (Q9VVI3) E3 ubiquitin-protein ligase Nedd-4 (EC 6.3.2.-) (DNedd4)| Length = 1007 Score = 40.8 bits (94), Expect = 0.003 Identities = 28/100 (28%), Positives = 47/100 (47%), Gaps = 6/100 (6%) Frame = -1 Query: 556 LSVTVISAEDIPAMDVMGKADPFVVLYLXXXXX-----XXXXXXXXXTLNPIWNQTFDFV 392 L + V++ + + D+ G +DP+V + L TLNP WN+ F F Sbjct: 72 LRIVVLTGQSLAKKDIFGASDPYVRIDLNTINGDINIDSVLTKTKKKTLNPTWNEEFIFR 131 Query: 391 VEDALHDLLMVEVWDHDTFGK-DYIGRCILTLTRAILEGE 275 V+ + H L+ +V+D + + D++G LTL E E Sbjct: 132 VKPSEHKLVF-QVFDENRLTRDDFLGMVELTLVNLPTEQE 170
>PUB1_SCHPO (Q92462) E3 ubiquitin--protein ligase pub1 (EC 6.3.2.-)| Length = 767 Score = 40.4 bits (93), Expect = 0.004 Identities = 23/76 (30%), Positives = 37/76 (48%) Frame = -1 Query: 556 LSVTVISAEDIPAMDVMGKADPFVVLYLXXXXXXXXXXXXXXTLNPIWNQTFDFVVEDAL 377 + VT+++A+ + DV DPF VL + LNP WN+TF+ V D Sbjct: 10 IRVTIVAADGLYKRDVFRFPDPFAVLTVDGEQTHTTTAIKKT-LNPYWNETFEVNVTD-- 66 Query: 376 HDLLMVEVWDHDTFGK 329 + + ++V+D F K Sbjct: 67 NSTIAIQVFDQKKFKK 82
>DOC2G_MOUSE (Q9ESN1) Double C2-like domain-containing protein gamma| (Doc2-gamma) Length = 387 Score = 40.0 bits (92), Expect = 0.006 Identities = 30/89 (33%), Positives = 41/89 (46%), Gaps = 6/89 (6%) Frame = -1 Query: 565 RGVLSVTVISAEDIPAMDVMGKADPFVVLYLXXXXXXXXXXXXXX---TLNPIWNQTFDF 395 RG L V V+ + MD G +DPFV L+L TLNP +N+ F + Sbjct: 257 RGGLLVGVLRCVHLAPMDANGYSDPFVRLFLHPSSGKKSKYKTSVRRKTLNPEFNEEFFY 316 Query: 394 VV--EDALHDLLMVEVWDHDT-FGKDYIG 317 E+ L+V VWD+D D+IG Sbjct: 317 AGHREELAQKALLVSVWDYDLGTADDFIG 345
>DOC2B_RAT (P70610) Double C2-like domain-containing protein beta (Doc2-beta)| Length = 412 Score = 40.0 bits (92), Expect = 0.006 Identities = 29/95 (30%), Positives = 42/95 (44%), Gaps = 7/95 (7%) Frame = -1 Query: 556 LSVTVISAEDIPAMDVMGKADPFVVLYL---XXXXXXXXXXXXXXTLNPIWNQT---FDF 395 L T+ A+ + MD G ADP+V L+L TLNP WN+T + Sbjct: 143 LHCTISKAKGLKPMDHNGLADPYVKLHLLPGASKANKLRTKTLRNTLNPSWNETLTYYGI 202 Query: 394 VVEDALHDLLMVEVWDHDTF-GKDYIGRCILTLTR 293 ED + L + V D D F ++IG + L + Sbjct: 203 TDEDMIRKTLRISVCDEDKFRHNEFIGETRVPLKK 237 Score = 39.3 bits (90), Expect = 0.010 Identities = 30/91 (32%), Positives = 43/91 (47%), Gaps = 7/91 (7%) Frame = -1 Query: 556 LSVTVISAEDIPAMDVMGKADPFVVLYL---XXXXXXXXXXXXXXTLNPIWNQTFDFVVE 386 L V ++ + AMD G +DP+V YL TLNP +N+ F + ++ Sbjct: 283 LLVGIVRCAHLAAMDANGYSDPYVKTYLKPDVDKKSKHKTAVKKKTLNPEFNEEFCYEIK 342 Query: 385 --DALHDLLMVEVWDHDTFGK--DYIGRCIL 305 D L V VWD+D GK D+IG +L Sbjct: 343 HGDLAKKTLEVTVWDYD-IGKSNDFIGGVVL 372
>KPC1_DROME (P05130) Protein kinase C, brain isozyme (EC 2.7.11.13) (PKC)| (dPKC53E(BR)) Length = 679 Score = 39.7 bits (91), Expect = 0.007 Identities = 26/98 (26%), Positives = 48/98 (48%), Gaps = 5/98 (5%) Frame = -1 Query: 595 DVNQRKNVITRGVLSVTVISAEDIPAMDVMGKADPFVVLYLX---XXXXXXXXXXXXXTL 425 ++N ++N++T V + ++ MD G +DP+V + L L Sbjct: 183 EINVKENLLT-----VQIKEGRNLIPMDPNGLSDPYVKVKLIPDDKDQSKKKTRTIKACL 237 Query: 424 NPIWNQTFDFVVEDALHD-LLMVEVWDHD-TFGKDYIG 317 NP+WN+T + ++ D +++EVWD D T D++G Sbjct: 238 NPVWNETLTYDLKPEDKDRRILIEVWDWDRTSRNDFMG 275
>DOC2B_MOUSE (P70169) Double C2-like domain-containing protein beta (Doc2-beta)| Length = 412 Score = 39.7 bits (91), Expect = 0.007 Identities = 29/95 (30%), Positives = 42/95 (44%), Gaps = 7/95 (7%) Frame = -1 Query: 556 LSVTVISAEDIPAMDVMGKADPFVVLYL---XXXXXXXXXXXXXXTLNPIWNQT---FDF 395 L T+ A+ + MD G ADP+V L+L TLNP WN+T + Sbjct: 143 LHCTISKAKGLKPMDHNGLADPYVKLHLLPGASKANKLRTKTLRNTLNPSWNETLTYYGI 202 Query: 394 VVEDALHDLLMVEVWDHDTF-GKDYIGRCILTLTR 293 ED + L + V D D F ++IG + L + Sbjct: 203 TDEDMVRKTLRISVCDEDKFRHNEFIGETRVPLKK 237 Score = 39.3 bits (90), Expect = 0.010 Identities = 30/91 (32%), Positives = 43/91 (47%), Gaps = 7/91 (7%) Frame = -1 Query: 556 LSVTVISAEDIPAMDVMGKADPFVVLYL---XXXXXXXXXXXXXXTLNPIWNQTFDFVVE 386 L V ++ + AMD G +DP+V YL TLNP +N+ F + ++ Sbjct: 283 LLVGIVRCAHLAAMDANGYSDPYVKTYLKPDVDKKSKHKTAVKKKTLNPEFNEEFCYEIK 342 Query: 385 --DALHDLLMVEVWDHDTFGK--DYIGRCIL 305 D L V VWD+D GK D+IG +L Sbjct: 343 HGDLAKKTLEVTVWDYD-IGKSNDFIGGVVL 372
>PLCL4_HUMAN (O75038) 1-phosphatidylinositol-4,5-bisphosphate| phosphodiesterase-like 4 (EC 3.1.4.11) (Phosphoinositide phospholipase C-like 4) (Phospholipase C-like 4) (Fragment) Length = 1182 Score = 39.7 bits (91), Expect = 0.007 Identities = 22/68 (32%), Positives = 36/68 (52%) Frame = -1 Query: 424 NPIWNQTFDFVVEDALHDLLMVEVWDHDTFGKDYIGRCILTLTRAILEGEFQDTYALQGA 245 NP W +T F+V L+ VWDHD G+D+IG+ TL + + ++ Y L+G Sbjct: 840 NPTWEETLVFMVHMPEIALVRFLVWDHDPIGRDFIGQ--RTLAFSSMMPGYRHVY-LEGM 896 Query: 244 KSGRLNLH 221 + + +H Sbjct: 897 EEASIFVH 904
>SYTL5_HUMAN (Q8TDW5) Synaptotagmin-like protein 5| Length = 730 Score = 39.7 bits (91), Expect = 0.007 Identities = 31/116 (26%), Positives = 51/116 (43%), Gaps = 7/116 (6%) Frame = -1 Query: 574 VITRGVLSVTVISAEDIPAMDVMGKADPFVVLYLX---XXXXXXXXXXXXXTLNPIWNQT 404 VI+ G+L V + A+++ A+ G +D FV YL ++NP WN T Sbjct: 583 VISGGILEVFIKEAKNLTAVKSGGTSDSFVKGYLLPDDSKATKHKTLVIKKSVNPQWNHT 642 Query: 403 FDFV---VEDALHDLLMVEVWDHDTFGKD-YIGRCILTLTRAILEGEFQDTYALQG 248 F F +D + L + +WD + F + ++G L + G+ D QG Sbjct: 643 FMFSGIHPQDIKNVCLELTIWDKEAFSSNIFLGGVRLNSGSGVSHGKNVDWMDSQG 698
>SMUF1_HUMAN (Q9HCE7) Smad ubiquitination regulatory factor 1 (EC 6.3.2.-)| (Ubiquitin--protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase 1) (hSMURF1) Length = 757 Score = 39.3 bits (90), Expect = 0.010 Identities = 25/94 (26%), Positives = 42/94 (44%), Gaps = 4/94 (4%) Frame = -1 Query: 556 LSVTVISAEDIPAMDVMGKADPFVVLYLXXXXXXXXXXXXXXTLNPIWNQTFDFVVEDAL 377 + +TV+ A+++ D DPF + + TL+P WNQ +D V Sbjct: 15 IRLTVLCAKNLAKKDFFRLPDPFAKIVVDGSGQCHSTDTVKNTLDPKWNQHYDLYVGKT- 73 Query: 376 HDLLMVEVWDHDTF----GKDYIGRCILTLTRAI 287 D + + VW+H G ++G C+ L+ AI Sbjct: 74 -DSITISVWNHKKIHKKQGAGFLG-CVRLLSNAI 105
>SMUF1_XENLA (Q9PUN2) Smad ubiquitination regulatory factor 1 (EC 6.3.2.-)| (Ubiquitin--protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase) (xSMURF1) Length = 731 Score = 39.3 bits (90), Expect = 0.010 Identities = 30/106 (28%), Positives = 48/106 (45%), Gaps = 9/106 (8%) Frame = -1 Query: 577 NVITR-GVLSV----TVISAEDIPAMDVMGKADPFVVLYLXXXXXXXXXXXXXXTLNPIW 413 NV+TR G S+ TV+ A+++ D DPF + + TL+P W Sbjct: 3 NVVTRRGGSSIRVRLTVLCAKNLAKRDFFRLPDPFAKIVVDGSGQCHSTDTVKNTLDPKW 62 Query: 412 NQTFDFVVEDALHDLLMVEVWDHDTF----GKDYIGRCILTLTRAI 287 NQ +D V D + + +W+H G ++G C+ L+ AI Sbjct: 63 NQHYDLYV--GKMDSITISIWNHKKIHKKQGAGFLG-CVRLLSNAI 105
>SMUF1_MOUSE (Q9CUN6) Smad ubiquitination regulatory factor 1 (EC 6.3.2.-)| (Ubiquitin--protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase 1) Length = 731 Score = 39.3 bits (90), Expect = 0.010 Identities = 25/94 (26%), Positives = 42/94 (44%), Gaps = 4/94 (4%) Frame = -1 Query: 556 LSVTVISAEDIPAMDVMGKADPFVVLYLXXXXXXXXXXXXXXTLNPIWNQTFDFVVEDAL 377 + +TV+ A+++ D DPF + + TL+P WNQ +D V Sbjct: 15 IRLTVLCAKNLAKKDFFRLPDPFAKIVVDGSGQCHSTDTVKNTLDPKWNQHYDLYVGKT- 73 Query: 376 HDLLMVEVWDHDTF----GKDYIGRCILTLTRAI 287 D + + VW+H G ++G C+ L+ AI Sbjct: 74 -DSITISVWNHKKIHKKQGAGFLG-CVRLLSNAI 105
>BAIP3_HUMAN (O94812) BAI1-associated protein 3 (BAP3)| Length = 1187 Score = 39.3 bits (90), Expect = 0.010 Identities = 14/29 (48%), Positives = 20/29 (68%) Frame = -1 Query: 427 LNPIWNQTFDFVVEDALHDLLMVEVWDHD 341 LNP+W + F F +ED D L +++WDHD Sbjct: 269 LNPVWKEHFLFEIEDVSTDQLHLDIWDHD 297 Score = 31.6 bits (70), Expect = 2.0 Identities = 26/96 (27%), Positives = 42/96 (43%), Gaps = 10/96 (10%) Frame = -1 Query: 556 LSVTVISAEDIPAMDVMGKADPFVVL-----YLXXXXXXXXXXXXXXTLNPIWNQTFDFV 392 L+V V+ A D+ +D G +DPFV++ +L TL+P++++ F F Sbjct: 1027 LAVEVLHAADLLPLDANGLSDPFVIVELGPPHLFPLVRSQRTQVKTRTLHPVYDELFYFS 1086 Query: 391 VEDAL----HDLLMVEVWDHDTFG-KDYIGRCILTL 299 V ++ V DHD D+ G L L Sbjct: 1087 VPAEACRRRAACVLFTVMDHDWLSTNDFAGEAALGL 1122
>SMUF2_HUMAN (Q9HAU4) Smad ubiquitination regulatory factor 2 (EC 6.3.2.-)| (Ubiquitin--protein ligase SMURF2) (Smad-specific E3 ubiquitin ligase 2) (hSMURF2) Length = 748 Score = 38.9 bits (89), Expect = 0.013 Identities = 25/94 (26%), Positives = 43/94 (45%), Gaps = 4/94 (4%) Frame = -1 Query: 556 LSVTVISAEDIPAMDVMGKADPFVVLYLXXXXXXXXXXXXXXTLNPIWNQTFDFVVEDAL 377 L +TV+ A+++ D DPF + + TL+P WNQ +D + + Sbjct: 14 LRLTVLCAKNLVKKDFFRLPDPFAKVVVDGSGQCHSTDTVKNTLDPKWNQHYDLYIGKS- 72 Query: 376 HDLLMVEVWDHDTF----GKDYIGRCILTLTRAI 287 D + + VW+H G ++G C+ L+ AI Sbjct: 73 -DSVTISVWNHKKIHKKQGAGFLG-CVRLLSNAI 104
>PA24A_HORSE (O77793) Cytosolic phospholipase A2 (cPLA2) (Phospholipase A2 group| IVA) [Includes: Phospholipase A2 (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase); Lysophospholipase (EC 3.1.1.5)] Length = 749 Score = 38.5 bits (88), Expect = 0.016 Identities = 17/74 (22%), Positives = 37/74 (50%), Gaps = 1/74 (1%) Frame = -1 Query: 514 DVMGKADPFVVLYLXXX-XXXXXXXXXXXTLNPIWNQTFDFVVEDALHDLLMVEVWDHDT 338 D++ DP+V L++ +NP+WN+TF+F+++ ++L + + D + Sbjct: 37 DMLDTPDPYVELFISSTPDSRKRTRHFNNNINPVWNETFEFILDPNQENVLEITLMDANY 96 Query: 337 FGKDYIGRCILTLT 296 + +G TL+ Sbjct: 97 VMDETLGTATFTLS 110
>RIM_CAEEL (Q22366) Rab-3-interacting molecule unc-10 (Rim) (Uncoordinated| protein 10) Length = 1563 Score = 38.5 bits (88), Expect = 0.016 Identities = 26/101 (25%), Positives = 45/101 (44%), Gaps = 7/101 (6%) Frame = -1 Query: 556 LSVTVISAEDIPAMDVMGKADPFVVLYLX---XXXXXXXXXXXXXTLNPIWNQTFDF--- 395 LSV ++ D+P +P+V ++L TL P+W++ F + Sbjct: 857 LSVALVRGFDLPPRSDGTPRNPYVKIFLLPDRSEKSRRQSAVIAETLMPVWDEVFYYNGL 916 Query: 394 VVEDALHDLLMVEVWDHDTFG-KDYIGRCILTLTRAILEGE 275 L +L + VWD+D FG ++G ++ L L+GE Sbjct: 917 TEPMLLQRVLELTVWDYDKFGTNSFLGETLIDLASVPLDGE 957
>Y1322_ARATH (Q9C8S6) C2 domain protein At1g63220| Length = 147 Score = 38.5 bits (88), Expect = 0.016 Identities = 27/101 (26%), Positives = 43/101 (42%), Gaps = 1/101 (0%) Frame = -1 Query: 562 GVLSVTVISAEDIPAMDVMGKADPFVVLYLXXXXXXXXXXXXXXTLNPIWNQTFDFVVED 383 G L V ++SA+ + D + DP+V L T P WN+TF F V + Sbjct: 4 GTLEVVLVSAKGLEDADFLNNMDPYVQLTCRTQDQKSNVAEGMGT-TPEWNETFIFTVSE 62 Query: 382 ALHDLLMVEVWDHDTFGK-DYIGRCILTLTRAILEGEFQDT 263 + L +++D D + D +G + L +EG T Sbjct: 63 GTTE-LKAKIFDKDVGTEDDAVGEATIPLEPVFVEGSIPPT 102
>UN13D_RAT (Q9R189) Unc-13 homolog D (Munc13-4)| Length = 1088 Score = 37.7 bits (86), Expect = 0.028 Identities = 31/98 (31%), Positives = 46/98 (46%), Gaps = 10/98 (10%) Frame = -1 Query: 556 LSVTVISAEDIPAMDVMGKADPFVVLYLXXXXXX-----XXXXXXXXTLNPIWNQTFDFV 392 L V ++SA + +D G +DPFV L L L+P++++TF+F+ Sbjct: 925 LHVELLSASSLLPLDSNGSSDPFVQLTLEPRHEFPELAPRETQKHKKELHPLFDETFEFL 984 Query: 391 V--EDALHD--LLMVEVWDHDTFGKDYI-GRCILTLTR 293 V E D L++ V DHD G D + G L L R Sbjct: 985 VPAEPCQKDGACLLLTVLDHDRLGADDLEGEAFLPLCR 1022 Score = 33.5 bits (75), Expect = 0.53 Identities = 25/97 (25%), Positives = 36/97 (37%), Gaps = 24/97 (24%) Frame = -1 Query: 556 LSVTVISAEDIPAMDVMGKADPF------------------------VVLYLXXXXXXXX 449 L TV A+ I DV G +DP+ VV + Sbjct: 113 LKATVKQAKGILGKDVSGFSDPYCLLGIEQKVGVPEGSPVSRRRQKAVVRHTIPEEETHR 172 Query: 448 XXXXXXTLNPIWNQTFDFVVEDALHDLLMVEVWDHDT 338 TLNP+W++TF ED + +++WD DT Sbjct: 173 TQVKTQTLNPVWDETFILEFEDITNASFHLDMWDLDT 209
>BAIP3_MOUSE (Q80TT2) BAI1-associated protein 3 (BAP3)| Length = 1134 Score = 37.7 bits (86), Expect = 0.028 Identities = 13/29 (44%), Positives = 20/29 (68%) Frame = -1 Query: 427 LNPIWNQTFDFVVEDALHDLLMVEVWDHD 341 LNP+W + F F ++D D L +++WDHD Sbjct: 232 LNPVWKEHFLFEIDDVNTDQLHLDIWDHD 260 Score = 32.3 bits (72), Expect = 1.2 Identities = 26/96 (27%), Positives = 42/96 (43%), Gaps = 10/96 (10%) Frame = -1 Query: 556 LSVTVISAEDIPAMDVMGKADPFVVL-----YLXXXXXXXXXXXXXXTLNPIWNQTFDFV 392 L+V V+ A D+ +D G +DPFV++ +L TL+P++++ F F Sbjct: 974 LAVEVLHAADLLPLDANGLSDPFVIVELGPPHLFPLVRSQRTQVKARTLHPVYDELFHFS 1033 Query: 391 VEDAL----HDLLMVEVWDHDTFG-KDYIGRCILTL 299 V ++ V DHD D+ G L L Sbjct: 1034 VPAEACRRRGACVLFTVMDHDWLSTNDFAGEAALGL 1069
>ERG3_ORYSA (Q7F9X0) Elicitor-responsive protein 3 (16 kDa phloem protein)| (RPP16) Length = 144 Score = 37.7 bits (86), Expect = 0.028 Identities = 25/104 (24%), Positives = 46/104 (44%), Gaps = 1/104 (0%) Frame = -1 Query: 571 ITRGVLSVTVISAEDIPAMDVMGKADPFVVLYLXXXXXXXXXXXXXXTLNPIWNQTFDFV 392 + +G L V ++ A+ + D + DP+ VL + +P WN+TF F Sbjct: 1 MVQGTLEVLLVGAKGLENTDYLCNMDPYAVLKCRSQEQKSSVASGKGS-DPEWNETFMFS 59 Query: 391 VEDALHDLLMVEVWDHDT-FGKDYIGRCILTLTRAILEGEFQDT 263 V +L+ +++ D D+ D++G ++L EG T Sbjct: 60 VTHNATELI-IKLMDSDSGTDDDFVGEATISLEAIYTEGSIPPT 102
>PP16B_CUCMA (Q9ZT46) 16 kDa phloem protein 2| Length = 137 Score = 37.7 bits (86), Expect = 0.028 Identities = 29/102 (28%), Positives = 46/102 (45%), Gaps = 7/102 (6%) Frame = -1 Query: 562 GVLSVTVISAEDIPAMDVMGKA-DPFVVLYLXXXXXXXXXXXXXXTLNPIWNQTFDFVVE 386 G++ V +IS + + A D + K DP+ + +PIWN+ F F+VE Sbjct: 3 GMMEVHLISGKGLQAHDPLNKPIDPYAEINFKGQERMSKVAKNAGP-DPIWNEKFKFLVE 61 Query: 385 -----DALHDLLMVEVWDHDTF-GKDYIGRCILTLTRAILEG 278 H ++ +V DHD G DYIG + + + EG Sbjct: 62 YPGSGGDFH--ILFKVMDHDAIDGDDYIGDVKIDVQNLLAEG 101
>PA24A_HUMAN (P47712) Cytosolic phospholipase A2 (cPLA2) (Phospholipase A2 group| IVA) [Includes: Phospholipase A2 (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase); Lysophospholipase (EC 3.1.1.5)] Length = 749 Score = 37.4 bits (85), Expect = 0.037 Identities = 16/74 (21%), Positives = 37/74 (50%), Gaps = 1/74 (1%) Frame = -1 Query: 514 DVMGKADPFVVLYLXXX-XXXXXXXXXXXTLNPIWNQTFDFVVEDALHDLLMVEVWDHDT 338 D++ DP+V L++ +NP+WN+TF+F+++ ++L + + D + Sbjct: 37 DMLDTPDPYVELFISTTPDSRKRTRHFNNDINPVWNETFEFILDPNQENVLEITLMDANY 96 Query: 337 FGKDYIGRCILTLT 296 + +G T++ Sbjct: 97 VMDETLGTATFTVS 110
>DOC2A_HUMAN (Q14183) Double C2-like domain-containing protein alpha| (Doc2-alpha) (Doc2) Length = 400 Score = 37.4 bits (85), Expect = 0.037 Identities = 32/90 (35%), Positives = 44/90 (48%), Gaps = 7/90 (7%) Frame = -1 Query: 565 RGVLSVTVISAEDIPAMDVMGKADPFVVLYL---XXXXXXXXXXXXXXTLNPIWNQTFDF 395 RG+L V ++ + AMDV G +DP+V YL TLNP +N+ F + Sbjct: 266 RGLL-VGILRCAHLAAMDVNGYSDPYVKTYLRPDVDKKSKHKTCVKKKTLNPEFNEEFFY 324 Query: 394 VVE--DALHDLLMVEVWDHDTFGK--DYIG 317 +E L V VWD+D GK D+IG Sbjct: 325 EIELSTLATKTLEVTVWDYD-IGKSNDFIG 353
>SYTL5_MOUSE (Q80T23) Synaptotagmin-like protein 5| Length = 753 Score = 37.0 bits (84), Expect = 0.048 Identities = 24/88 (27%), Positives = 40/88 (45%), Gaps = 6/88 (6%) Frame = -1 Query: 571 ITRGVLSVTVISAEDIPAMDVMGKADPFVVLYLX---XXXXXXXXXXXXXTLNPIWNQTF 401 I+ G+L V + A+++ A+ G +D FV YL ++NP WN TF Sbjct: 607 ISGGILEVFIKKAKNLTAVKSGGTSDSFVKGYLLPDDNKATKHKTAVVKKSVNPEWNHTF 666 Query: 400 DF---VVEDALHDLLMVEVWDHDTFGKD 326 F +D + L + +WD + F + Sbjct: 667 IFSGLYPQDIKNACLELTIWDKEAFSSN 694
>DOC2A_MOUSE (Q7TNF0) Double C2-like domain-containing protein alpha| (Doc2-alpha) Length = 405 Score = 37.0 bits (84), Expect = 0.048 Identities = 30/87 (34%), Positives = 41/87 (47%), Gaps = 7/87 (8%) Frame = -1 Query: 556 LSVTVISAEDIPAMDVMGKADPFVVLYL---XXXXXXXXXXXXXXTLNPIWNQTFDFVVE 386 L V ++ + AMDV G +DP+V YL TLNP +N+ F + +E Sbjct: 273 LLVGIVRCAHLAAMDVNGYSDPYVKTYLRPDVDKKSKHKTCVKKKTLNPEFNEEFFYEIE 332 Query: 385 --DALHDLLMVEVWDHDTFGK--DYIG 317 L V VWD+D GK D+IG Sbjct: 333 LSTLATKTLEVTVWDYD-IGKSNDFIG 358
>RASL1_MOUSE (Q9Z268) RasGAP-activating-like protein 1| Length = 799 Score = 37.0 bits (84), Expect = 0.048 Identities = 23/81 (28%), Positives = 36/81 (44%) Frame = -1 Query: 562 GVLSVTVISAEDIPAMDVMGKADPFVVLYLXXXXXXXXXXXXXXTLNPIWNQTFDFVVED 383 G LS+ V+ +PA DV G +DP+ ++ + +L+P W + + + Sbjct: 5 GSLSIRVVEGRALPAKDVSGSSDPYCLVKV-DDQVVARTATIWRSLSPFWGEEYTVHLPL 63 Query: 382 ALHDLLMVEVWDHDTFGKDYI 320 H L V D DT G D I Sbjct: 64 DFHHLAFY-VLDEDTVGHDDI 83 Score = 33.1 bits (74), Expect = 0.69 Identities = 20/77 (25%), Positives = 31/77 (40%), Gaps = 1/77 (1%) Frame = -1 Query: 544 VISAEDIPAMDVMGKADPFVVLYLXXXXXXXXXXXXXXTLNPIWNQTFDFVVEDALHDLL 365 V A D+ D+ G +DPF ++ P W++ + L Sbjct: 139 VRQARDLAPRDISGTSDPFARVFWGNHSLETSTIKKTRF--PHWDEVLELREAPGTTSPL 196 Query: 364 MVEVWDHDTFGK-DYIG 317 VE+WD D GK D++G Sbjct: 197 RVELWDWDMVGKNDFLG 213
>RIMS2_MOUSE (Q9EQZ7) Regulating synaptic membrane exocytosis protein 2| (Rab3-interacting molecule 2) (RIM 2) (Rab3-interacting protein 2) Length = 1530 Score = 36.2 bits (82), Expect = 0.081 Identities = 25/103 (24%), Positives = 47/103 (45%), Gaps = 9/103 (8%) Frame = -1 Query: 556 LSVTVISAEDIPAMDVMGKADPFVVLYL---XXXXXXXXXXXXXXTLNPIWNQTFDFVV- 389 L VT++ A+D+P+ + +P+V +Y TL P WNQTF + Sbjct: 831 LIVTILGAKDLPSREDGRPRNPYVKIYFLPDRSDKNKRRTKTVKKTLEPKWNQTFIYSPV 890 Query: 388 --EDALHDLLMVEVWDHDTFGK---DYIGRCILTLTRAILEGE 275 + +L + +WD + +++G ++ L A+L+ E Sbjct: 891 HRREFRERMLEITLWDQARVREEESEFLGEILIELETALLDDE 933
>RIMS2_HUMAN (Q9UQ26) Regulating synaptic membrane exocytosis protein 2| (Rab3-interacting molecule 2) (RIM 2) Length = 1411 Score = 36.2 bits (82), Expect = 0.081 Identities = 25/103 (24%), Positives = 47/103 (45%), Gaps = 9/103 (8%) Frame = -1 Query: 556 LSVTVISAEDIPAMDVMGKADPFVVLYL---XXXXXXXXXXXXXXTLNPIWNQTFDFVV- 389 L VT++ A+D+P+ + +P+V +Y TL P WNQTF + Sbjct: 822 LIVTILGAKDLPSREDGRPRNPYVKIYFLPDRSDKNKRRTKTVKKTLEPKWNQTFIYSPV 881 Query: 388 --EDALHDLLMVEVWDHDTFGK---DYIGRCILTLTRAILEGE 275 + +L + +WD + +++G ++ L A+L+ E Sbjct: 882 HRREFRERMLEITLWDQARVREEESEFLGEILIELETALLDDE 924
>RIMS2_RAT (Q9JIS1) Regulating synaptic membrane exocytosis protein 2| (Rab3-interacting molecule 2) (RIM 2) Length = 1555 Score = 36.2 bits (82), Expect = 0.081 Identities = 25/103 (24%), Positives = 47/103 (45%), Gaps = 9/103 (8%) Frame = -1 Query: 556 LSVTVISAEDIPAMDVMGKADPFVVLYL---XXXXXXXXXXXXXXTLNPIWNQTFDFVV- 389 L VT++ A+D+P+ + +P+V +Y TL P WNQTF + Sbjct: 760 LIVTILGAKDLPSREDGRPRNPYVKIYFLPDRSDKNKRRTKTVKKTLEPKWNQTFIYSPV 819 Query: 388 --EDALHDLLMVEVWDHDTFGK---DYIGRCILTLTRAILEGE 275 + +L + +WD + +++G ++ L A+L+ E Sbjct: 820 HRREFRERMLEITLWDQARVREEESEFLGEILIELETALLDDE 862
>DOC2A_RAT (P70611) Double C2-like domain-containing protein alpha| (Doc2-alpha) Length = 403 Score = 36.2 bits (82), Expect = 0.081 Identities = 30/87 (34%), Positives = 41/87 (47%), Gaps = 7/87 (8%) Frame = -1 Query: 556 LSVTVISAEDIPAMDVMGKADPFVVLYL---XXXXXXXXXXXXXXTLNPIWNQTFDFVVE 386 L V ++ + AMDV G +DP+V YL TLNP +N+ F + +E Sbjct: 271 LLVGIVRCAHLAAMDVNGYSDPYVKTYLRPDVDKKSKHKTCVKKKTLNPEFNEEFFYEME 330 Query: 385 --DALHDLLMVEVWDHDTFGK--DYIG 317 L V VWD+D GK D+IG Sbjct: 331 LSTLATKTLEVTVWDYD-IGKSNDFIG 356
>ITSN1_MOUSE (Q9Z0R4) Intersectin-1 (EH and SH3 domains protein 1)| Length = 1714 Score = 35.8 bits (81), Expect = 0.11 Identities = 21/84 (25%), Positives = 37/84 (44%), Gaps = 1/84 (1%) Frame = -1 Query: 562 GVLSVTVISAEDIPAMDVMGKADPFVVLYLXXXXXXXXXXXXXXTLNPIWNQTFDFVVED 383 G L V V+ ++ GK++P+ + + LNP WN F + D Sbjct: 1589 GRLMVNVVEGIELKPCRSHGKSNPYCEVTMGSQCHITKTIQDT--LNPKWNSNCQFFIRD 1646 Query: 382 ALHDLLMVEVWDHDTFG-KDYIGR 314 ++L + V++ D F D++GR Sbjct: 1647 LEQEVLCITVFERDQFSPDDFLGR 1670
>ITSN1_HUMAN (Q15811) Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17)| Length = 1721 Score = 35.8 bits (81), Expect = 0.11 Identities = 21/84 (25%), Positives = 37/84 (44%), Gaps = 1/84 (1%) Frame = -1 Query: 562 GVLSVTVISAEDIPAMDVMGKADPFVVLYLXXXXXXXXXXXXXXTLNPIWNQTFDFVVED 383 G L V V+ ++ GK++P+ + + LNP WN F + D Sbjct: 1596 GRLMVNVVEGIELKPCRSHGKSNPYCEVTMGSQCHITKTIQDT--LNPKWNSNCQFFIRD 1653 Query: 382 ALHDLLMVEVWDHDTFG-KDYIGR 314 ++L + V++ D F D++GR Sbjct: 1654 LEQEVLCITVFERDQFSPDDFLGR 1677
>RIMS1_HUMAN (Q86UR5) Regulating synaptic membrane exocytosis protein 1| (Rab3-interacting molecule 1) (RIM 1) Length = 1692 Score = 35.8 bits (81), Expect = 0.11 Identities = 27/103 (26%), Positives = 43/103 (41%), Gaps = 9/103 (8%) Frame = -1 Query: 556 LSVTVISAEDIPAMDVMGKADPFVVLYL---XXXXXXXXXXXXXXTLNPIWNQTFDFV-- 392 L V V+ A D+PA +P+V +Y L P WNQTF + Sbjct: 759 LIVNVLQATDLPARVDGRPRNPYVKMYFLPDRSDKSKRRTKTVKKILEPKWNQTFVYSHV 818 Query: 391 -VEDALHDLLMVEVWDHDTFGK---DYIGRCILTLTRAILEGE 275 D +L + VWD + +++G ++ L A+L+ E Sbjct: 819 HRRDFRERMLEITVWDQPRVQEEESEFLGEILIELETALLDDE 861
>PA24A_RAT (P50393) Cytosolic phospholipase A2 (cPLA2) (Phospholipase A2 group| IVA) [Includes: Phospholipase A2 (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase); Lysophospholipase (EC 3.1.1.5)] Length = 752 Score = 35.4 bits (80), Expect = 0.14 Identities = 14/57 (24%), Positives = 30/57 (52%), Gaps = 1/57 (1%) Frame = -1 Query: 514 DVMGKADPFVVLYLXXX-XXXXXXXXXXXTLNPIWNQTFDFVVEDALHDLLMVEVWD 347 D++ DP+V L++ +NP+WN+TF+F+++ ++L + + D Sbjct: 37 DMLDTPDPYVELFISTTPDSRKRTRHFNNDINPVWNETFEFILDPNQENVLEITLMD 93
>PA24A_MOUSE (P47713) Cytosolic phospholipase A2 (cPLA2) (Phospholipase A2 group| IVA) [Includes: Phospholipase A2 (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase); Lysophospholipase (EC 3.1.1.5)] Length = 748 Score = 35.4 bits (80), Expect = 0.14 Identities = 14/57 (24%), Positives = 30/57 (52%), Gaps = 1/57 (1%) Frame = -1 Query: 514 DVMGKADPFVVLYLXXX-XXXXXXXXXXXTLNPIWNQTFDFVVEDALHDLLMVEVWD 347 D++ DP+V L++ +NP+WN+TF+F+++ ++L + + D Sbjct: 37 DMLDTPDPYVELFISTTPDSRKRTRHFNNDINPVWNETFEFILDPNQENVLEITLMD 93
>PP16A_CUCMA (Q9ZT47) 16 kDa phloem protein 1| Length = 149 Score = 35.4 bits (80), Expect = 0.14 Identities = 27/102 (26%), Positives = 45/102 (44%), Gaps = 7/102 (6%) Frame = -1 Query: 562 GVLSVTVISAEDIPAMDVMGKA-DPFVVLYLXXXXXXXXXXXXXXTLNPIWNQTFDFVVE 386 G++ V +IS + + A D + K DP+ + NP+W++ F F+ E Sbjct: 3 GMMEVHLISGKGLQAHDPLNKPIDPYAEINFKGQERMSKVAKNAGP-NPLWDEKFKFLAE 61 Query: 385 -----DALHDLLMVEVWDHDTF-GKDYIGRCILTLTRAILEG 278 H ++ +V DHD G DYIG + + + EG Sbjct: 62 YPGSGGDFH--ILFKVMDHDAIDGDDYIGDVKIDVKNLLAEG 101
>PA24A_BRARE (P50392) Cytosolic phospholipase A2 (cPLA2) (Phospholipase A2 group| IVA) [Includes: Phospholipase A2 (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase); Lysophospholipase (EC 3.1.1.5)] Length = 741 Score = 35.0 bits (79), Expect = 0.18 Identities = 22/92 (23%), Positives = 45/92 (48%), Gaps = 4/92 (4%) Frame = -1 Query: 556 LSVTVISAEDIPAM---DVMGKADPFVVLYLXXX-XXXXXXXXXXXTLNPIWNQTFDFVV 389 L +TV+ AE++ D++ DP+V L + +NP WN+TF+F++ Sbjct: 14 LKLTVVRAENVTKGAFGDLLDTPDPYVELSVPTTPESRKRTRHINNDINPKWNETFEFIL 73 Query: 388 EDALHDLLMVEVWDHDTFGKDYIGRCILTLTR 293 + ++L V + D + + +G +L++ Sbjct: 74 DPNQSNVLEVTLMDANYVMDETLGTAKYSLSK 105
>UN13D_HUMAN (Q70J99) Unc-13 homolog D (Munc13-4)| Length = 1090 Score = 35.0 bits (79), Expect = 0.18 Identities = 25/86 (29%), Positives = 40/86 (46%), Gaps = 9/86 (10%) Frame = -1 Query: 556 LSVTVISAEDIPAMDVMGKADPFVVLYLXXXX-----XXXXXXXXXXTLNPIWNQTFDFV 392 L V ++SA + +D G +DPFV L L L+P++++TF+F+ Sbjct: 927 LRVELLSASSLLPLDSNGSSDPFVQLTLEPRHEFPELAARETQKHKKDLHPLFDETFEFL 986 Query: 391 VE----DALHDLLMVEVWDHDTFGKD 326 V L++ V D+DT G D Sbjct: 987 VPAEPCRKAGACLLLTVLDYDTLGAD 1012 Score = 33.5 bits (75), Expect = 0.53 Identities = 25/97 (25%), Positives = 36/97 (37%), Gaps = 24/97 (24%) Frame = -1 Query: 556 LSVTVISAEDIPAMDVMGKADPF------------------------VVLYLXXXXXXXX 449 L TV A+ I DV G +DP+ VV + Sbjct: 113 LKATVKQAKGILGKDVSGFSDPYCLLGIEQGVGVPGGSPGSRHRQKAVVRHTIPEEETHR 172 Query: 448 XXXXXXTLNPIWNQTFDFVVEDALHDLLMVEVWDHDT 338 TLNP+W++TF ED + +++WD DT Sbjct: 173 TQVITQTLNPVWDETFILEFEDITNASFHLDMWDLDT 209
>RASL1_HUMAN (O95294) RasGAP-activating-like protein 1| Length = 804 Score = 35.0 bits (79), Expect = 0.18 Identities = 20/77 (25%), Positives = 32/77 (41%), Gaps = 1/77 (1%) Frame = -1 Query: 544 VISAEDIPAMDVMGKADPFVVLYLXXXXXXXXXXXXXXTLNPIWNQTFDFVVEDALHDLL 365 V+ A D+ D+ G +DPF ++ P W++ + L Sbjct: 139 VLQARDLAPRDISGTSDPFARVFWGSQSLETSTIKKTRF--PHWDEVLELREMPGAPSPL 196 Query: 364 MVEVWDHDTFGK-DYIG 317 VE+WD D GK D++G Sbjct: 197 RVELWDWDMVGKNDFLG 213 Score = 34.7 bits (78), Expect = 0.24 Identities = 22/79 (27%), Positives = 34/79 (43%) Frame = -1 Query: 556 LSVTVISAEDIPAMDVMGKADPFVVLYLXXXXXXXXXXXXXXTLNPIWNQTFDFVVEDAL 377 L+V V+ +PA DV G +DP+ ++ + +L P W + + + Sbjct: 7 LNVRVVEGRALPAKDVSGSSDPYCLVKV-DDEVVARTATVWRSLGPFWGEEYTVHLPLDF 65 Query: 376 HDLLMVEVWDHDTFGKDYI 320 H L V D DT G D I Sbjct: 66 HQLAFY-VLDEDTVGHDDI 83
>NEDD4_HUMAN (P46934) E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-)| Length = 1000 Score = 35.0 bits (79), Expect = 0.18 Identities = 24/82 (29%), Positives = 38/82 (46%), Gaps = 4/82 (4%) Frame = -1 Query: 559 VLSVTVISAEDIPAMDVMGKADPFV--VLY--LXXXXXXXXXXXXXXTLNPIWNQTFDFV 392 ++ V VI+ + D++G +DP+V LY + +LNP WN+ F Sbjct: 120 IVRVRVIAGIGLAKKDILGASDPYVRVTLYDPMNGVLTSVQTKTIKKSLNPKWNEEILFR 179 Query: 391 VEDALHDLLMVEVWDHDTFGKD 326 V H LL EV+D + +D Sbjct: 180 VHPQQHRLLF-EVFDENRLTRD 200
>CPNE5_MOUSE (Q8JZW4) Copine-5 (Copine V)| Length = 593 Score = 35.0 bits (79), Expect = 0.18 Identities = 31/98 (31%), Positives = 41/98 (41%), Gaps = 9/98 (9%) Frame = -1 Query: 535 AEDIPAMDVMGKADPFVVLYLXXXXXXXX----XXXXXXTLNPIWNQTFDFVVEDALHD- 371 A + D GK+DPF+V Y TLNP+W QTF V + Sbjct: 185 ANKLDKKDFFGKSDPFLVFYRSNEDGTFTICHKTEVMKNTLNPVW-QTFSIPVRALCNGD 243 Query: 370 ---LLMVEVWDHDTFGK-DYIGRCILTLTRAILEGEFQ 269 + VEV+D D G D+IG T R + G+ Q Sbjct: 244 YDRTIKVEVYDWDRDGSHDFIGE-FTTSYRELARGQSQ 280
>CPNE5_HUMAN (Q9HCH3) Copine-5 (Copine V)| Length = 593 Score = 35.0 bits (79), Expect = 0.18 Identities = 31/98 (31%), Positives = 41/98 (41%), Gaps = 9/98 (9%) Frame = -1 Query: 535 AEDIPAMDVMGKADPFVVLYLXXXXXXXX----XXXXXXTLNPIWNQTFDFVVEDALHD- 371 A + D GK+DPF+V Y TLNP+W QTF V + Sbjct: 185 ANKLDKKDFFGKSDPFLVFYRSNEDGTFTICHKTEVMKNTLNPVW-QTFSIPVRALCNGD 243 Query: 370 ---LLMVEVWDHDTFGK-DYIGRCILTLTRAILEGEFQ 269 + VEV+D D G D+IG T R + G+ Q Sbjct: 244 YDRTIKVEVYDWDRDGSHDFIGE-FTTSYRELARGQSQ 280
>PA24A_CHICK (P49147) Cytosolic phospholipase A2 (cPLA2) (Phospholipase A2 group| IVA) [Includes: Phospholipase A2 (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase); Lysophospholipase (EC 3.1.1.5)] Length = 748 Score = 34.7 bits (78), Expect = 0.24 Identities = 20/75 (26%), Positives = 38/75 (50%), Gaps = 4/75 (5%) Frame = -1 Query: 559 VLSVTVISAEDIPAM---DVMGKADPFVVLYLXXXXX-XXXXXXXXXTLNPIWNQTFDFV 392 V +VTV A ++ D++ DP+V L++ +NP+WN+TF+F+ Sbjct: 19 VFTVTVRKATNVTKGAIGDMLDTPDPYVELFIPSAPDCRKRTKHFNNDVNPVWNETFEFI 78 Query: 391 VEDALHDLLMVEVWD 347 ++ ++L V + D Sbjct: 79 LDPNQDNVLEVTLMD 93
>NEDD4_RAT (Q62940) E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-)| Length = 887 Score = 33.9 bits (76), Expect = 0.40 Identities = 24/82 (29%), Positives = 38/82 (46%), Gaps = 4/82 (4%) Frame = -1 Query: 559 VLSVTVISAEDIPAMDVMGKADPFV--VLY--LXXXXXXXXXXXXXXTLNPIWNQTFDFV 392 V+ V VI+ + D++G +DP+V LY + +LNP WN+ F Sbjct: 76 VVRVKVIAGIGLAKKDILGASDPYVRVTLYDPMSGVLTSVQTKTIKKSLNPKWNEEILFR 135 Query: 391 VEDALHDLLMVEVWDHDTFGKD 326 V H +L EV+D + +D Sbjct: 136 VLPQQHRILF-EVFDENRLTRD 156
>NEDD4_MOUSE (P46935) E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-) (Neural| precursor cell expressed developmentally down-regulated protein 4) Length = 887 Score = 33.9 bits (76), Expect = 0.40 Identities = 24/82 (29%), Positives = 38/82 (46%), Gaps = 4/82 (4%) Frame = -1 Query: 559 VLSVTVISAEDIPAMDVMGKADPFV--VLY--LXXXXXXXXXXXXXXTLNPIWNQTFDFV 392 V+ V VI+ + D++G +DP+V LY + +LNP WN+ F Sbjct: 79 VVRVKVIAGIGLAKKDILGASDPYVRVTLYDPMSGILTSVQTKTIKKSLNPKWNEEILFR 138 Query: 391 VEDALHDLLMVEVWDHDTFGKD 326 V H +L EV+D + +D Sbjct: 139 VLPQRHRILF-EVFDENRLTRD 159
>RIMS1_RAT (Q9JIR4) Regulating synaptic membrane exocytosis protein 1| (Rab3-interacting molecule 1) (RIM 1) Length = 1615 Score = 33.5 bits (75), Expect = 0.53 Identities = 26/103 (25%), Positives = 41/103 (39%), Gaps = 9/103 (8%) Frame = -1 Query: 556 LSVTVISAEDIPAMDVMGKADPFVVLYLX---XXXXXXXXXXXXXTLNPIWNQTFDFV-- 392 L V V+ A D+P +P+V +Y L P WNQTF + Sbjct: 773 LIVNVLQATDLPPRVDGRPRNPYVKMYFLPDRSDKSKRRTKTVKKLLEPKWNQTFVYSHV 832 Query: 391 -VEDALHDLLMVEVWDHDTF---GKDYIGRCILTLTRAILEGE 275 D +L + VWD +++G ++ L A+L+ E Sbjct: 833 HRRDFRERMLEITVWDQPRVQDEESEFLGEILIELETALLDDE 875
>PIPA_DICDI (Q02158) 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase| (EC 3.1.4.11) (PLC) (Phosphoinositide phospholipase C) Length = 801 Score = 33.5 bits (75), Expect = 0.53 Identities = 26/91 (28%), Positives = 38/91 (41%), Gaps = 8/91 (8%) Frame = -1 Query: 556 LSVTVISAEDIPAMDVMGKA---DPFVVLYLXXXXXXXXXXXXXXT----LNPIWNQTFD 398 L V VISA +P K DP+V L + NP W + F+ Sbjct: 676 LIVNVISARQLPKYTKSTKGEVIDPYVTLSIVGTHFDQKVEKTKVIDNNGFNPHWGEEFE 735 Query: 397 FVVEDALHDLLMVEVWDHDTFGKDYIG-RCI 308 F + ++ +L++ V D D G + IG CI Sbjct: 736 FPLYNSQLSMLLIRVDDKDKVGHNRIGHHCI 766
>YMH2_YEAST (Q03640) Hypothetical 171.1 kDa protein in RPL6A-DAK1 intergenic| region Length = 1545 Score = 33.5 bits (75), Expect = 0.53 Identities = 33/138 (23%), Positives = 60/138 (43%), Gaps = 8/138 (5%) Frame = -1 Query: 562 GVLSVTVISAEDIPAMD-VMGKADPFVVL----YLXXXXXXXXXXXXXXTLNPIWNQTFD 398 GVL+VT+ SA+ + D + DP++V+ + NP WN+T Sbjct: 491 GVLAVTIASADSLKGSDFITNTVDPYIVMTTEDAVPGTDEEVRTSIKSNVKNPRWNET-K 549 Query: 397 FVVEDALHDLLMVEVWDHDTFGKD-YIGRCILTLTRAILEGEFQD--TYALQGAKSGRLN 227 +++ + L L ++ +D + KD IG L L +L+ D T L+ + Sbjct: 550 YLLLNTLEQKLNLKCFDFNDVRKDTVIGDLQLDLA-DLLQNPVLDNQTAELRSGTKSKGI 608 Query: 226 LHFKWTAQPIYRDRDRDQ 173 LH+ P+ D+ ++ Sbjct: 609 LHYSLHWFPVKEDKSEEK 626
>CPNE8_MOUSE (Q9DC53) Copine-8 (Copine VIII)| Length = 564 Score = 32.7 bits (73), Expect = 0.90 Identities = 30/98 (30%), Positives = 40/98 (40%), Gaps = 9/98 (9%) Frame = -1 Query: 535 AEDIPAMDVMGKADPFVVLYLXXXXXXXX----XXXXXXTLNPIWNQTFDFVVEDALHD- 371 A + D GK+DPF+V Y TLNP+W Q F V + Sbjct: 166 ANKLDKKDFFGKSDPFLVFYRSNEDGSFTICHKTEVVKNTLNPVW-QAFKISVRALCNGD 224 Query: 370 ---LLMVEVWDHDTFGK-DYIGRCILTLTRAILEGEFQ 269 + VEV+D D G D+IG T R + G+ Q Sbjct: 225 YDRTIKVEVYDWDRDGSHDFIGE-FTTSYRELARGQSQ 261
>MYOF_HUMAN (Q9NZM1) Myoferlin (Fer-1-like protein 3)| Length = 2061 Score = 32.7 bits (73), Expect = 0.90 Identities = 20/90 (22%), Positives = 39/90 (43%), Gaps = 1/90 (1%) Frame = -1 Query: 550 VTVISAEDIPAMDVMGKADPFVVLYLXXXXXXXXXXXXXXTLNPIWNQTFDFVVEDALHD 371 + ++ ++ D G DP++ + L TLNP++ + ++ Sbjct: 1557 IYIVRGLELQPQDNNGLCDPYIKITLGKKVIEDRDHYIPNTLNPVFGRMYELSCYLPQEK 1616 Query: 370 LLMVEVWDHDTFGKD-YIGRCILTLTRAIL 284 L + V+D+DTF +D +G I+ L L Sbjct: 1617 DLKISVYDYDTFTRDEKVGETIIDLENRFL 1646 Score = 30.0 bits (66), Expect = 5.8 Identities = 23/91 (25%), Positives = 42/91 (46%), Gaps = 10/91 (10%) Frame = -1 Query: 544 VISAEDIPAMDVMGKADPFVVLYLXXXXXXXXXXXXXXTLNPIWNQTFDFVVEDALHD-- 371 V A ++ A+D +DP+ ++ TLNP W+QT F + + Sbjct: 1145 VYQARNLLALDKDSFSDPYA--HICFLHRSKTTEIIHSTLNPTWDQTIIFDEVEIYGEPQ 1202 Query: 370 -------LLMVEVWDHDTFGKD-YIGRCILT 302 +++E++D+D GKD ++GR I + Sbjct: 1203 TVLQNPPKVIMELFDNDQVGKDEFLGRSIFS 1233
>YNP2_YEAST (P53901) Hypothetical 46.2 kDa protein in YCK2-RPC8 intergenic| region Length = 409 Score = 32.7 bits (73), Expect = 0.90 Identities = 25/94 (26%), Positives = 42/94 (44%), Gaps = 1/94 (1%) Frame = -1 Query: 565 RGVLSVTVISAEDIPAMDVMGKADPFVVLYLXXXXXXXXXXXXXXTLNPIWNQTFDFVVE 386 +G+LSV V A D+P ++ + K + + L + NP+++ F + Sbjct: 10 QGILSVYVSKARDLPNLNKLDKQNVMLRLRIAHMTRASNTLHRAGQ-NPVFHYLEKFDIT 68 Query: 385 DALHDLLMVEVW-DHDTFGKDYIGRCILTLTRAI 287 + L+ VEV+ D IGRC + L AI Sbjct: 69 PEIKPLMYVEVYCDRRKKSPLPIGRCEIDLLNAI 102
>CPNE8_HUMAN (Q86YQ8) Copine-8 (Copine VIII)| Length = 564 Score = 32.3 bits (72), Expect = 1.2 Identities = 30/98 (30%), Positives = 40/98 (40%), Gaps = 9/98 (9%) Frame = -1 Query: 535 AEDIPAMDVMGKADPFVVLYLXXXXXXXX----XXXXXXTLNPIWNQTFDFVVEDALHD- 371 A + D GK+DPF+V Y TLNP+W Q F V + Sbjct: 166 ANKLDKKDFFGKSDPFLVFYRSNEDGSFTICHKTEVVKNTLNPVW-QAFKISVRALCNGD 224 Query: 370 ---LLMVEVWDHDTFGK-DYIGRCILTLTRAILEGEFQ 269 + VEV+D D G D+IG T R + G+ Q Sbjct: 225 YDRTIKVEVYDWDRDGSHDFIGE-FTTSYRELSRGQSQ 261
>ADT2_PONPY (Q5R5A1) ADP/ATP translocase 2 (Adenine nucleotide translocator 2)| (ANT 2) (ADP,ATP carrier protein 2) (Solute carrier family 25 member 5) Length = 297 Score = 31.6 bits (70), Expect = 2.0 Identities = 20/67 (29%), Positives = 30/67 (44%) Frame = +3 Query: 420 GFNVSVTTLVFFLVSPFFRYRTTNGSAFPITSIAGMSSADITVTERTPLVITFFLWLTSY 599 GFNVSV ++ + + F Y T G + + I ++ +T LTSY Sbjct: 175 GFNVSVQGIIIYRAAYFGIYDTAKG------MLPDPKNTHIVISWMIAQTVTAVAGLTSY 228 Query: 600 PLDSVLR 620 P D+V R Sbjct: 229 PFDTVRR 235
>ADT2_HUMAN (P05141) ADP/ATP translocase 2 (Adenine nucleotide translocator 2)| (ANT 2) (ADP,ATP carrier protein 2) (Solute carrier family 25 member 5) (ADP,ATP carrier protein, fibroblast isoform) Length = 297 Score = 31.6 bits (70), Expect = 2.0 Identities = 20/67 (29%), Positives = 30/67 (44%) Frame = +3 Query: 420 GFNVSVTTLVFFLVSPFFRYRTTNGSAFPITSIAGMSSADITVTERTPLVITFFLWLTSY 599 GFNVSV ++ + + F Y T G + + I ++ +T LTSY Sbjct: 175 GFNVSVQGIIIYRAAYFGIYDTAKG------MLPDPKNTHIVISWMIAQTVTAVAGLTSY 228 Query: 600 PLDSVLR 620 P D+V R Sbjct: 229 PFDTVRR 235
>SMUF1_DROME (Q9V853) E3 ubiquitin-protein ligase Smurf1 (EC 6.3.2.-) (Smad| ubiquitination regulatory factor 1 homolog) (DSmurf) (Lethal with a checkpoint kinase protein) Length = 1061 Score = 31.6 bits (70), Expect = 2.0 Identities = 14/68 (20%), Positives = 30/68 (44%) Frame = -1 Query: 550 VTVISAEDIPAMDVMGKADPFVVLYLXXXXXXXXXXXXXXTLNPIWNQTFDFVVEDALHD 371 +T++ A ++ D+ DPF + + +L+P WN +D + + D Sbjct: 17 ITILCARNLARKDLFRLPDPFAKVQVDGTGQVYSTEISKSSLDPKWNAHYDLFL--GIGD 74 Query: 370 LLMVEVWD 347 + + VW+ Sbjct: 75 AITITVWN 82
>PUB3_SCHPO (O14326) E3 ubiquitin--protein ligase pub3 (EC 6.3.2.-)| Length = 786 Score = 30.8 bits (68), Expect = 3.4 Identities = 15/72 (20%), Positives = 34/72 (47%) Frame = -1 Query: 544 VISAEDIPAMDVMGKADPFVVLYLXXXXXXXXXXXXXXTLNPIWNQTFDFVVEDALHDLL 365 +++A+ + D+ + DPF +L + +NP WN+ F+ V+ + ++ Sbjct: 12 IVAADGLSKRDLFRQPDPFAILTVDGEQTHTTKVIKKS-VNPYWNEGFEVTVKPS--SVI 68 Query: 364 MVEVWDHDTFGK 329 + ++D F K Sbjct: 69 SIRLFDQKKFKK 80
>CO3_EPTBU (P98094) Complement C3 [Contains: Complement C3 beta chain;| Complement C3 alpha chain; C3a anaphylatoxin; Complement C3 gamma chain] (Fragment) Length = 1620 Score = 30.8 bits (68), Expect = 3.4 Identities = 18/54 (33%), Positives = 26/54 (48%) Frame = +3 Query: 459 VSPFFRYRTTNGSAFPITSIAGMSSADITVTERTPLVITFFLWLTSYPLDSVLR 620 V P + N S I + GM +A ++RT V+T W +PL+SV R Sbjct: 1546 VIPMHCGKNLNVSPGDIYLVMGMHNAHWRNSDRTQYVLTSDTWFEKFPLESVCR 1599
>Y147_HAEIN (P44543) Putative TRAP transporter permease protein HI0147| Length = 633 Score = 30.8 bits (68), Expect = 3.4 Identities = 18/63 (28%), Positives = 31/63 (49%), Gaps = 2/63 (3%) Frame = +3 Query: 426 NVSVTTLVFFLVSPFFRY--RTTNGSAFPITSIAGMSSADITVTERTPLVITFFLWLTSY 599 N V LVF + F + RT NG++FPI ++ G+S I ++ F ++ + Sbjct: 101 NTFVQLLVFICIFLFIHFGIRTFNGASFPIDALGGISEKWIFAALPVVAILMMFRFIQAQ 160 Query: 600 PLD 608 L+ Sbjct: 161 TLN 163
>NUP82_YEAST (P40368) Nucleoporin NUP82 (Nuclear pore protein NUP82)| Length = 713 Score = 30.4 bits (67), Expect = 4.5 Identities = 26/80 (32%), Positives = 39/80 (48%), Gaps = 5/80 (6%) Frame = +3 Query: 216 LKCRFSLPDLA-----PCSAYVSWNSPSSIALVSVKMHLPM*SFPNVSWSHTSTISKSCR 380 LK L D+A P AY++WN S++AL+S K +F N+S S S + Sbjct: 408 LKFESKLEDIATIERIPNLAYINWNDQSNLALMSNKTL----TFQNIS-SDMKPQSTAAE 462 Query: 381 ASSTTKSNV*FHIGFNVSVT 440 S +T+ + GF +S T Sbjct: 463 TSISTEKSDTVGDGFKMSFT 482
>ADT2_RAT (Q09073) ADP/ATP translocase 2 (Adenine nucleotide translocator 2)| (ANT 2) (ADP,ATP carrier protein 2) (Solute carrier family 25 member 5) Length = 297 Score = 30.0 bits (66), Expect = 5.8 Identities = 20/67 (29%), Positives = 30/67 (44%) Frame = +3 Query: 420 GFNVSVTTLVFFLVSPFFRYRTTNGSAFPITSIAGMSSADITVTERTPLVITFFLWLTSY 599 GFNVSV ++ + + F Y T G + + I ++ +T LTSY Sbjct: 175 GFNVSVQGIIIYRAAYFGIYDTAKG------MLPDPKNTHIFISWMIAQSVTAVAGLTSY 228 Query: 600 PLDSVLR 620 P D+V R Sbjct: 229 PFDTVRR 235
>ADT2_MOUSE (P51881) ADP/ATP translocase 2 (Adenine nucleotide translocator 2)| (ANT 2) (ADP,ATP carrier protein 2) (Solute carrier family 25 member 5) Length = 297 Score = 30.0 bits (66), Expect = 5.8 Identities = 20/67 (29%), Positives = 30/67 (44%) Frame = +3 Query: 420 GFNVSVTTLVFFLVSPFFRYRTTNGSAFPITSIAGMSSADITVTERTPLVITFFLWLTSY 599 GFNVSV ++ + + F Y T G + + I ++ +T LTSY Sbjct: 175 GFNVSVQGIIIYRAAYFGIYDTAKG------MLPDPKNTHIFISWMIAQSVTAVAGLTSY 228 Query: 600 PLDSVLR 620 P D+V R Sbjct: 229 PFDTVRR 235
>ADT2_BOVIN (Q8SQH5) ADP/ATP translocase 2 (Adenine nucleotide translocator 2)| (ANT 2) (ADP,ATP carrier protein 2) (Solute carrier family 25 member 5) Length = 297 Score = 30.0 bits (66), Expect = 5.8 Identities = 20/67 (29%), Positives = 30/67 (44%) Frame = +3 Query: 420 GFNVSVTTLVFFLVSPFFRYRTTNGSAFPITSIAGMSSADITVTERTPLVITFFLWLTSY 599 GFNVSV ++ + + F Y T G + + I ++ +T LTSY Sbjct: 175 GFNVSVQGIIIYRAAYFGIYDTAKG------MLPDPKNTHIFISWMIAQSVTAVAGLTSY 228 Query: 600 PLDSVLR 620 P D+V R Sbjct: 229 PFDTVRR 235
>CPNE7_HUMAN (Q9UBL6) Copine-7 (Copine VII)| Length = 633 Score = 30.0 bits (66), Expect = 5.8 Identities = 29/105 (27%), Positives = 42/105 (40%), Gaps = 16/105 (15%) Frame = -1 Query: 535 AEDIPAMDVMGKADPFVVLYL----XXXXXXXXXXXXXXTLNPIWNQTFDFVVEDALHDL 368 A + D+ K+DPF+ LY LNP+W + +L L Sbjct: 238 ARKLDDKDLFSKSDPFLELYRVNDDQGLQLVYRTEVVKNNLNPVWE-----AFKVSLSSL 292 Query: 367 LMVE--------VWDHDTFGK-DYIGRCILT---LTRAILEGEFQ 269 E VWD+D+ GK D+IG T + +A EG+ Q Sbjct: 293 CSCEETRPLKCLVWDYDSRGKHDFIGEFSTTFEEMQKAFEEGQAQ 337
>SYTL4_MOUSE (Q9R0Q1) Synaptotagmin-like protein 4 (Exophilin-2) (Granuphilin)| Length = 673 Score = 29.6 bits (65), Expect = 7.6 Identities = 16/64 (25%), Positives = 31/64 (48%), Gaps = 5/64 (7%) Frame = -1 Query: 502 KADPFVVLYLX---XXXXXXXXXXXXXTLNPIWNQTFDFVVEDAL--HDLLMVEVWDHDT 338 +++P+V YL T+NP++++TF + + ++L L VW H Sbjct: 394 RSNPYVKTYLLPDKSRQGKRKTSIKRDTINPLYDETFRYEISESLLAQRTLQFSVWHHGR 453 Query: 337 FGKD 326 FG++ Sbjct: 454 FGRN 457
>ADT1_RABIT (O46373) ADP/ATP translocase 1 (Adenine nucleotide translocator 1)| (ANT 1) (ADP,ATP carrier protein 1) (Solute carrier family 25 member 4) (30 kDa calsequestrin-binding protein) (CSQ-binding 30 kDa protein) Length = 297 Score = 29.6 bits (65), Expect = 7.6 Identities = 20/67 (29%), Positives = 29/67 (43%) Frame = +3 Query: 420 GFNVSVTTLVFFLVSPFFRYRTTNGSAFPITSIAGMSSADITVTERTPLVITFFLWLTSY 599 GFNVSV ++ + + F Y T G + + I V+ +T L SY Sbjct: 175 GFNVSVQGIIIYRAAYFGVYDTAKG------MLPDPKNVHIIVSWMIAQTVTAVAGLVSY 228 Query: 600 PLDSVLR 620 P D+V R Sbjct: 229 PFDTVRR 235
>ADT1_BOVIN (P02722) ADP/ATP translocase 1 (Adenine nucleotide translocator 1)| (ANT 1) (ADP,ATP carrier protein 1) (Solute carrier family 25 member 4) (ADP,ATP carrier protein, heart isoform T1) Length = 297 Score = 29.6 bits (65), Expect = 7.6 Identities = 20/67 (29%), Positives = 29/67 (43%) Frame = +3 Query: 420 GFNVSVTTLVFFLVSPFFRYRTTNGSAFPITSIAGMSSADITVTERTPLVITFFLWLTSY 599 GFNVSV ++ + + F Y T G + + I V+ +T L SY Sbjct: 175 GFNVSVQGIIIYRAAYFGVYDTAKG------MLPDPKNVHIIVSWMIAQTVTAVAGLVSY 228 Query: 600 PLDSVLR 620 P D+V R Sbjct: 229 PFDTVRR 235
>SYTL4_RAT (Q8VHQ7) Synaptotagmin-like protein 4 (Exophilin-2) (Granuphilin)| Length = 672 Score = 29.6 bits (65), Expect = 7.6 Identities = 16/64 (25%), Positives = 31/64 (48%), Gaps = 5/64 (7%) Frame = -1 Query: 502 KADPFVVLYLX---XXXXXXXXXXXXXTLNPIWNQTFDFVVEDAL--HDLLMVEVWDHDT 338 +++P+V YL T+NP++++TF + + ++L L VW H Sbjct: 393 RSNPYVKTYLLPDKSRQGKRKTSIKRDTINPLYDETFRYEISESLLAQRTLQFSVWHHGR 452 Query: 337 FGKD 326 FG++ Sbjct: 453 FGRN 456
>GLTJ_ECOLI (P0AER3) Glutamate/aspartate transport system permease protein gltJ| Length = 246 Score = 29.6 bits (65), Expect = 7.6 Identities = 17/66 (25%), Positives = 30/66 (45%), Gaps = 5/66 (7%) Frame = +3 Query: 420 GFNVSVTT-----LVFFLVSPFFRYRTTNGSAFPITSIAGMSSADITVTERTPLVITFFL 584 GF V++ ++ FLV FF T + F ++G+ + + + PL++ FF Sbjct: 28 GFQVTIALSICAWIIAFLVGSFFGILRTVPNRF----LSGLGTLYVELFRNVPLIVQFFT 83 Query: 585 WLTSYP 602 W P Sbjct: 84 WYLVIP 89
>GLTJ_ECOL6 (P0AER4) Glutamate/aspartate transport system permease protein gltJ| Length = 246 Score = 29.6 bits (65), Expect = 7.6 Identities = 17/66 (25%), Positives = 30/66 (45%), Gaps = 5/66 (7%) Frame = +3 Query: 420 GFNVSVTT-----LVFFLVSPFFRYRTTNGSAFPITSIAGMSSADITVTERTPLVITFFL 584 GF V++ ++ FLV FF T + F ++G+ + + + PL++ FF Sbjct: 28 GFQVTIALSICAWIIAFLVGSFFGILRTVPNRF----LSGLGTLYVELFRNVPLIVQFFT 83 Query: 585 WLTSYP 602 W P Sbjct: 84 WYLVIP 89
>MOG1_CAEEL (P34498) Probable pre-mRNA-splicing factor ATP-dependent RNA helicase| mog-1 (EC 3.6.1.-) (Sex determination protein mog-1) (Masculinization of germ line protein 1) Length = 1131 Score = 29.3 bits (64), Expect = 10.0 Identities = 18/52 (34%), Positives = 26/52 (50%), Gaps = 1/52 (1%) Frame = +2 Query: 308 DASPYVILSKCIMVPYFHHKQIMQGI-FYYKIKCLIPYRIQCLSHNPCLLFG 460 + S + I+ KCI YFH+ ++GI Y ++ IP C H LFG Sbjct: 972 NGSEWDIVRKCICSAYFHNAARLKGIGEYVNVRTGIP----CFLHPTSALFG 1019
>PLCD1_MOUSE (Q8R3B1) 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase| delta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-delta-1) (Phospholipase C-delta-1) (PLC-III) Length = 756 Score = 29.3 bits (64), Expect = 10.0 Identities = 26/90 (28%), Positives = 43/90 (47%), Gaps = 9/90 (10%) Frame = -1 Query: 556 LSVTVISAEDIPAMDVMGKA--DPFVVLYLXXX----XXXXXXXXXXXTLNPIWNQTFDF 395 L V +IS + +P ++ + DP V++ + NP W+ F+F Sbjct: 631 LRVWIISGQQLPKVNKNKNSIVDPKVIVEIHGVGQDVASRQTAVITNNGFNPRWDTEFEF 690 Query: 394 VVEDALHDLLMVE--VWDHDTFGK-DYIGR 314 VV A+ DL +V V D+D+ K D+IG+ Sbjct: 691 VV--AVPDLALVRFMVEDYDSSSKNDFIGQ 718
>CPNE6_MOUSE (Q9Z140) Copine-6 (Copine VI) (Neuronal-copine) (N-copine)| Length = 557 Score = 29.3 bits (64), Expect = 10.0 Identities = 34/159 (21%), Positives = 57/159 (35%), Gaps = 24/159 (15%) Frame = -1 Query: 580 KNVITRGVLSVTVISAE---------------DIPAMDVMGKADPFVVLYLXXXXXXX-- 452 KN T G ++T+++ E + D+ K+DPF+ +Y Sbjct: 130 KNGKTAGKSTITIVAEEVSGTNDYVQLTFRAHKLDNKDLFSKSDPFMEIYKTNGDQSDQL 189 Query: 451 --XXXXXXXTLNPIWNQ---TFDFVVEDALHDLLMVEVWDHDTFGK-DYIGRCILTLTRA 290 LNP W + + +H L V+D+D+ GK D+I Sbjct: 190 VWRTEVVKNNLNPSWEPFRLSLHSLCSCDIHRPLKFLVYDYDSSGKHDFI---------- 239 Query: 289 ILEGEFQDTYALQGAKSGRLNLHFKWTA-QPIYRDRDRD 176 GEF T+ + +W P YRD+ ++ Sbjct: 240 ---GEFTSTFQEMQEGTANPGQEMQWDCINPKYRDKKKN 275 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 94,009,711 Number of Sequences: 219361 Number of extensions: 2031145 Number of successful extensions: 5140 Number of sequences better than 10.0: 162 Number of HSP's better than 10.0 without gapping: 4769 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 5070 length of database: 80,573,946 effective HSP length: 107 effective length of database: 57,102,319 effective search space used: 5767334219 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)