>OSBP1_RABIT (P16258) Oxysterol-binding protein 1|
          Length = 809

 Score = 40.4 bits (93), Expect(2) = 6e-08
 Identities = 17/32 (53%), Positives = 26/32 (81%)
 Frame = -3

Query: 625 RRCLENGEYERANAEKLRLEQRQRQARKMQES 530
           +R +ENG ++ ANAEK RLE++QR +RK +E+
Sbjct: 723 QRLMENGRWDEANAEKQRLEEKQRLSRKKREA 754



 Score = 35.8 bits (81), Expect(2) = 6e-08
 Identities = 12/19 (63%), Positives = 13/19 (68%)
 Frame = -2

Query: 470 GGYWESREKSSWEGCPDIF 414
           G YWE +EK  W  CPDIF
Sbjct: 791 GEYWECKEKQDWNSCPDIF 809

>OSBP1_HUMAN (P22059) Oxysterol-binding protein 1|
          Length = 807

 Score = 40.4 bits (93), Expect(2) = 6e-08
 Identities = 17/32 (53%), Positives = 26/32 (81%)
 Frame = -3

Query: 625 RRCLENGEYERANAEKLRLEQRQRQARKMQES 530
           +R +ENG ++ ANAEK RLE++QR +RK +E+
Sbjct: 721 QRLMENGRWDEANAEKQRLEEKQRLSRKKREA 752



 Score = 35.8 bits (81), Expect(2) = 6e-08
 Identities = 12/19 (63%), Positives = 13/19 (68%)
 Frame = -2

Query: 470 GGYWESREKSSWEGCPDIF 414
           G YWE +EK  W  CPDIF
Sbjct: 789 GEYWECKEKQDWSSCPDIF 807

>OSBP2_HUMAN (Q969R2) Oxysterol-binding protein 2 (Oxysterol-binding|
           protein-related protein 4) (OSBP-related protein 4)
           (ORP-4)
          Length = 916

 Score = 36.6 bits (83), Expect(2) = 2e-06
 Identities = 12/19 (63%), Positives = 15/19 (78%)
 Frame = -2

Query: 470 GGYWESREKSSWEGCPDIF 414
           GGYWE++EK  W  CP+IF
Sbjct: 898 GGYWEAKEKQDWHMCPNIF 916



 Score = 34.3 bits (77), Expect(2) = 2e-06
 Identities = 15/40 (37%), Positives = 24/40 (60%)
 Frame = -3

Query: 625 RRCLENGEYERANAEKLRLEQRQRQARKMQESGWKPRVVC 506
           +R +E G ++ AN EK RLE++QR +R+ +     P   C
Sbjct: 826 QRLMEKGRWDEANTEKQRLEEKQRLSRRRRLEACGPGSSC 865

>YEH1_SCHPO (O13944) Oxysterol-binding protein homolog C23H4.01c|
          Length = 945

 Score = 32.7 bits (73), Expect(2) = 1e-04
 Identities = 17/40 (42%), Positives = 23/40 (57%), Gaps = 3/40 (7%)
 Frame = -3

Query: 625 RRCLENGEYERANAEKLRLEQRQRQARKMQES---GWKPR 515
           +R  EN + + A   KL LEQ+QR+ RK  E     W+PR
Sbjct: 862 QRYRENNDLDHAEPLKLELEQKQRERRKEMEEKDIKWEPR 901



 Score = 32.0 bits (71), Expect(2) = 1e-04
 Identities = 10/17 (58%), Positives = 13/17 (76%)
 Frame = -2

Query: 464 YWESREKSSWEGCPDIF 414
           YWESRE S+W  CP ++
Sbjct: 929 YWESRENSTWSSCPKLW 945

>OSH1_YEAST (P35845) Oxysterol-binding protein homolog 1|
          Length = 1188

 Score = 38.9 bits (89), Expect(2) = 2e-04
 Identities = 17/31 (54%), Positives = 25/31 (80%)
 Frame = -3

Query: 625  RRCLENGEYERANAEKLRLEQRQRQARKMQE 533
            +R +ENGEY++A AEK R+E +QR A+K +E
Sbjct: 1112 QRAMENGEYDKAAAEKHRVEVKQRAAKKERE 1142



 Score = 25.0 bits (53), Expect(2) = 2e-04
 Identities = 8/20 (40%), Positives = 12/20 (60%)
 Frame = -2

Query: 473  SGGYWESREKSSWEGCPDIF 414
            +G YW  R+   ++ C DIF
Sbjct: 1169 NGEYWNKRKNHDFKDCADIF 1188

>YB35_SCHPO (O14340) Oxysterol-binding protein homolog C2F12.05c|
          Length = 1310

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 20/41 (48%), Positives = 30/41 (73%), Gaps = 4/41 (9%)
 Frame = -3

Query: 625  RRCLENGEYERANAEKLRLEQRQRQARKMQESG----WKPR 515
            +R +ENG+Y+ A +EK RLE++QR+ R+M+E G    W PR
Sbjct: 1223 QRAMENGQYDLAASEKNRLEEKQRKKRRMREQGEMPPWSPR 1263

>OSBL1_RAT (Q8K4M9) Oxysterol-binding protein-related protein 1 (OSBP-related|
            protein 1) (ORP-1)
          Length = 950

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 21/44 (47%), Positives = 28/44 (63%), Gaps = 3/44 (6%)
 Frame = -3

Query: 622  RCLENGEYERANAEKLRLEQRQRQARK---MQESGWKPRVVCEG 500
            R +ENGE ++A+ EK RLE++QR ARK     E  WK R   +G
Sbjct: 879  RAMENGEIDQASEEKKRLEEKQRAARKNRSKSEEDWKTRWFHQG 922

>OSBL1_HUMAN (Q9BXW6) Oxysterol-binding protein-related protein 1 (OSBP-related|
            protein 1) (ORP-1)
          Length = 950

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 21/44 (47%), Positives = 28/44 (63%), Gaps = 3/44 (6%)
 Frame = -3

Query: 622  RCLENGEYERANAEKLRLEQRQRQARK---MQESGWKPRVVCEG 500
            R +ENGE ++A+ EK RLE++QR ARK     E  WK R   +G
Sbjct: 879  RAMENGEIDQASEEKKRLEEKQRAARKNRSKSEEDWKTRWFHQG 922

>OSBL1_MOUSE (Q91XL9) Oxysterol-binding protein-related protein 1 (OSBP-related|
            protein 1) (ORP-1)
          Length = 950

 Score = 39.7 bits (91), Expect = 0.008
 Identities = 21/44 (47%), Positives = 27/44 (61%), Gaps = 3/44 (6%)
 Frame = -3

Query: 622  RCLENGEYERANAEKLRLEQRQRQARK---MQESGWKPRVVCEG 500
            R +ENGE + A+ EK RLE++QR ARK     E  WK R   +G
Sbjct: 879  RAMENGEIDLASEEKKRLEEKQRAARKNRSKSEEDWKTRWFHQG 922

>OSH2_YEAST (Q12451) Oxysterol-binding protein homolog 2|
          Length = 1283

 Score = 35.8 bits (81), Expect(2) = 0.011
 Identities = 14/31 (45%), Positives = 23/31 (74%)
 Frame = -3

Query: 625  RRCLENGEYERANAEKLRLEQRQRQARKMQE 533
            +R +E+G Y+ A  EK R+E++QR AR+ +E
Sbjct: 1207 QRAMEDGRYDEAGDEKFRVEEKQRAARRKRE 1237



 Score = 22.3 bits (46), Expect(2) = 0.011
 Identities = 10/29 (34%), Positives = 13/29 (44%)
 Frame = -2

Query: 500  IKVATHTATSGGYWESREKSSWEGCPDIF 414
            I  A +   +G YW  R     + C DIF
Sbjct: 1255 ITKAKYWRYTGKYWVKRRDHDLKDCGDIF 1283

>OSBP2_MOUSE (Q5QNQ6) Oxysterol-binding protein 2|
          Length = 908

 Score = 36.6 bits (83), Expect = 0.065
 Identities = 12/19 (63%), Positives = 15/19 (78%)
 Frame = -2

Query: 470 GGYWESREKSSWEGCPDIF 414
           GGYWE++EK  W  CP+IF
Sbjct: 890 GGYWEAKEKKDWHMCPNIF 908



 Score = 33.1 bits (74), Expect = 0.72
 Identities = 13/28 (46%), Positives = 21/28 (75%)
 Frame = -3

Query: 625 RRCLENGEYERANAEKLRLEQRQRQARK 542
           +R +E G ++ AN EK RLE++QR +R+
Sbjct: 820 QRLMERGRWDEANTEKQRLEEKQRLSRR 847

>OSBL2_MOUSE (Q8BX94) Oxysterol-binding protein-related protein 2 (OSBP-related|
           protein 2) (ORP-2)
          Length = 484

 Score = 35.4 bits (80), Expect = 0.15
 Identities = 17/39 (43%), Positives = 27/39 (69%), Gaps = 3/39 (7%)
 Frame = -3

Query: 622 RCLENGEYERANAEKLRLEQRQRQARK---MQESGWKPR 515
           R +ENG  + A+ EK RLE++QR+ARK    +++ W+ R
Sbjct: 413 RGMENGNMDLASQEKERLEEKQREARKERAKEDAEWRTR 451

>OSBL2_HUMAN (Q9H1P3) Oxysterol-binding protein-related protein 2 (OSBP-related|
           protein 2) (ORP-2)
          Length = 480

 Score = 35.0 bits (79), Expect = 0.19
 Identities = 17/39 (43%), Positives = 27/39 (69%), Gaps = 3/39 (7%)
 Frame = -3

Query: 622 RCLENGEYERANAEKLRLEQRQRQARK---MQESGWKPR 515
           R +ENG  + A+ EK RLE++QR+AR+    +E+ W+ R
Sbjct: 409 RGMENGNMDLASQEKERLEEKQREARRERAKEEAEWQTR 447

>SYA_BUCBP (P59420) Alanyl-tRNA synthetase (EC 6.1.1.7) (Alanine--tRNA ligase)|
           (AlaRS)
          Length = 880

 Score = 33.1 bits (74), Expect = 0.72
 Identities = 12/32 (37%), Positives = 21/32 (65%)
 Frame = +3

Query: 171 NPHKKTSIQSDLLDERHSYYVRKNNVSERAAF 266
           N HK+ SI  + L+ R++YY+  NN++ +  F
Sbjct: 431 NQHKQNSINKNFLNTRNAYYIEDNNINIKTHF 462

>DBNL_MOUSE (Q62418) Drebrin-like protein (SH3 domain-containing protein 7)|
           (Actin-binding protein 1)
          Length = 436

 Score = 32.0 bits (71), Expect = 1.6
 Identities = 20/58 (34%), Positives = 31/58 (53%)
 Frame = -3

Query: 604 EYERANAEKLRLEQRQRQARKMQESGWKPRVVCEG*R*RHIPLPRVVTGNPEKRAAGK 431
           E  RA  E+ RLE+ +R+ R++QE+  + +   E  R    P P   TG PE+ A  +
Sbjct: 194 EKRRAEEERQRLEEERRE-RELQEAARREQRYQEQHRSAGAPSPSSRTGEPEQEAVSR 250

>OSBL3_HUMAN (Q9H4L5) Oxysterol-binding protein-related protein 3 (OSBP-related|
           protein 3) (ORP-3)
          Length = 887

 Score = 30.8 bits (68), Expect = 3.6
 Identities = 14/31 (45%), Positives = 20/31 (64%)
 Frame = -3

Query: 625 RRCLENGEYERANAEKLRLEQRQRQARKMQE 533
           +R LE G  E A  +K R+EQ QR+ R++ E
Sbjct: 814 QRFLEEGNLEEAEIQKQRIEQLQRERRRVLE 844

>OSBL3_MOUSE (Q9DBS9) Oxysterol-binding protein-related protein 3 (OSBP-related|
           protein 3) (ORP-3)
          Length = 855

 Score = 30.8 bits (68), Expect = 3.6
 Identities = 13/31 (41%), Positives = 21/31 (67%)
 Frame = -3

Query: 625 RRCLENGEYERANAEKLRLEQRQRQARKMQE 533
           +R LE G+ E A  +K R+E+ QR+ R++ E
Sbjct: 782 QRLLEEGDIEEAEVQKQRIEKLQRERRRVLE 812

>KES1_USTMA (P0C199) Protein KES1|
          Length = 383

 Score = 30.0 bits (66), Expect = 6.1
 Identities = 12/33 (36%), Positives = 21/33 (63%)
 Frame = -3

Query: 616 LENGEYERANAEKLRLEQRQRQARKMQESGWKP 518
           + +G++E A+ +K R+E  QRQ RK + +   P
Sbjct: 312 IRSGDFETASKDKARIENAQRQKRKDEAAAGTP 344

>ZNF28_HUMAN (P17035) Zinc finger protein 28 (Zinc finger protein KOX24)|
          Length = 665

 Score = 29.6 bits (65), Expect = 8.0
 Identities = 13/45 (28%), Positives = 27/45 (60%)
 Frame = +3

Query: 171 NPHKKTSIQSDLLDERHSYYVRKNNVSERAAFCLQAERHFNCSSI 305
           N +   S+ S LL ++ + ++R     E++  C+++ + FNCSS+
Sbjct: 137 NKYGNNSLHSSLLTQKRNVHMR-----EKSFQCIESGKSFNCSSL 176

>MEND_ECOLI (P17109) Menaquinone biosynthesis protein menD [Includes:|
           2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate
           synthase (EC 2.5.1.64) (SHCHC synthase); 2-oxoglutarate
           decarboxylase (EC 4.1.1.71) (Alpha-ketoglutarate
           decarboxylase) (KDC)]
          Length = 556

 Score = 29.6 bits (65), Expect = 8.0
 Identities = 20/71 (28%), Positives = 34/71 (47%)
 Frame = +1

Query: 421 SGQPSQLLFSLDSQ*PPEVAVCVATFILRKPPEVSTHSPASFVPAVVFAQASTSQHLLFH 600
           +G   + L  L +  PPE+  C A   +R+P   ++H P   +      Q   ++ L+  
Sbjct: 93  AGLTGEKLILLTADRPPELIDCGANQAIRQPGMFASH-PTHSISLPRPTQDIPARWLVST 151

Query: 601 IHHSLGTFWSG 633
           I H+LGT  +G
Sbjct: 152 IDHALGTLHAG 162

>MLO10_ARATH (Q9FKY5) MLO-like protein 10 (AtMlo10)|
          Length = 569

 Score = 29.6 bits (65), Expect = 8.0
 Identities = 15/38 (39%), Positives = 20/38 (52%)
 Frame = +2

Query: 14  TASRCHRLIRDMLPLGHTISMHALLFFGASMHSTYSDI 127
           T+SRC      ++P      +H LLFF A+ H  YS I
Sbjct: 142 TSSRCDEGHEPLIPATGLHQLHILLFFMAAFHILYSFI 179

>5HT5B_RAT (P35365) 5-hydroxytryptamine 5B receptor (5-HT-5B) (Serotonin|
           receptor 5B) (MR22)
          Length = 370

 Score = 29.6 bits (65), Expect = 8.0
 Identities = 19/63 (30%), Positives = 32/63 (50%), Gaps = 1/63 (1%)
 Frame = -2

Query: 341 FFWNLLVPFLVVYTRAI-KMPFRL*AEGCPFRYIVFPYIIRVSFVQKVTLNRCFLVGISL 165
           F WNLLV   ++  RA  ++P  L A       +V   ++ +S V +++  R + +G SL
Sbjct: 67  FLWNLLVLVTILRVRAFHRVPHNLVASTAVSDVLVAALVMPLSLVSELSAGRRWQLGRSL 126

Query: 164 AQV 156
             V
Sbjct: 127 CHV 129

>SRD26_CAEEL (P92015) Serpentine receptor class delta-26 (Protein srd-26)|
          Length = 317

 Score = 29.6 bits (65), Expect = 8.0
 Identities = 12/33 (36%), Positives = 18/33 (54%)
 Frame = -1

Query: 204 GHSESMFSCGDFTRTGSECCYIGHLCISEYVEC 106
           G S  +   G  TR G   CY+GH+ +  ++EC
Sbjct: 65  GSSILVIPTGPCTRLGPTACYVGHMFMLCFLEC 97


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 95,839,210
Number of Sequences: 219361
Number of extensions: 2035678
Number of successful extensions: 5147
Number of sequences better than 10.0: 23
Number of HSP's better than 10.0 without gapping: 4962
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5143
length of database: 80,573,946
effective HSP length: 108
effective length of database: 56,882,958
effective search space used: 6029593548
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)