ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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更新日：2016年5月1日

Clone Information

BLAST Search Result

Clone Name rbasd2a12
Clone Library Name barley_pub
No. Definition Score
(bits)		 E
Value
1DHGY_CUCSA (P13443) Glycerate dehydrogenase (EC 1.1.1.29) (NADH-... 193 2e-58
2GYAR_THELI (Q9C4M5) Glyoxylate reductase (EC 1.1.1.26) (Glycolat... 68 4e-16
3GYAR_PYRHO (O58320) Glyoxylate reductase (EC 1.1.1.26) (Glycolat... 65 1e-15
4GYAR_PYRAB (Q9UYR1) Glyoxylate reductase (EC 1.1.1.26) (Glycolat... 62 4e-15
5GYAR_PYRKO (Q5JEZ2) Glyoxylate reductase (EC 1.1.1.26) (Glycolat... 63 9e-14
6GYAR_PYRFU (Q8U3Y2) Glyoxylate reductase (EC 1.1.1.26) (Glycolat... 60 3e-12
7TKRA_ENTAG (P58000) 2-ketogluconate reductase (EC 1.1.1.215) (2K... 59 8e-12
8TKRA_ECOLI (P37666) 2-ketogluconate reductase (EC 1.1.1.215) (2K... 62 1e-11
9TKRA_ECO57 (P58220) 2-ketogluconate reductase (EC 1.1.1.215) (2K... 62 1e-11
10GYAR_AERPE (Q9YAW4) Glyoxylate reductase (EC 1.1.1.26) (Glycolat... 52 7e-10
11YEAA_SCHPO (O14075) Putative 2-hydroxyacid dehydrogenase UNK4.10... 57 9e-09
12SERA_METJA (Q58424) D-3-phosphoglycerate dehydrogenase (EC 1.1.1... 43 3e-08
13YN14_YEAST (P53839) Putative 2-hydroxyacid dehydrogenase YNL274C... 48 3e-08
14SERA_ARATH (O04130) D-3-phosphoglycerate dehydrogenase, chloropl... 52 4e-08
15TKRA_BACSU (O32264) Probable 2-ketogluconate reductase (EC 1.1.1... 49 2e-07
16SERA_METTH (O27051) D-3-phosphoglycerate dehydrogenase (EC 1.1.1... 48 3e-07
17SERA_BACSU (P35136) D-3-phosphoglycerate dehydrogenase (EC 1.1.1... 47 6e-07
18Y1556_HAEIN (P45250) Putative 2-hydroxyacid dehydrogenase HI1556... 40 7e-07
19DHGY_METEX (Q59516) Glycerate dehydrogenase (EC 1.1.1.29) (NADH-... 42 3e-06
20SERA_ARCFU (O29445) D-3-phosphoglycerate dehydrogenase (EC 1.1.1... 51 4e-06
21GRHPR_HUMAN (Q9UBQ7) Glyoxylate reductase/hydroxypyruvate reduct... 50 5e-06
22SERA_SYNY3 (P73821) D-3-phosphoglycerate dehydrogenase (EC 1.1.1... 42 2e-05
23SERA_MYCLE (O33116) D-3-phosphoglycerate dehydrogenase (EC 1.1.1... 45 2e-05
24GRHPR_MOUSE (Q91Z53) Glyoxylate reductase/hydroxypyruvate reduct... 48 2e-05
25CTBP2_HUMAN (P56545) C-terminal-binding protein 2 (CtBP2) 36 1e-04
26CTBP2_MOUSE (P56546) C-terminal-binding protein 2 (CtBP2) 36 1e-04
27SERA_MYCTU (P0A544) D-3-phosphoglycerate dehydrogenase (EC 1.1.1... 42 2e-04
28SERA_MYCBO (P0A545) D-3-phosphoglycerate dehydrogenase (EC 1.1.1... 42 2e-04
29PTXD_PSEST (O69054) Phosphonate dehydrogenase (EC 1.20.1.1) (NAD... 37 2e-04
30DHGY_HYPME (P36234) Glycerate dehydrogenase (EC 1.1.1.29) (NADH-... 44 3e-04
31CTBP_DROME (O46036) C-terminal-binding protein (CtBP protein) (d... 35 4e-04
32PDXB_PHOLL (Q7N2B2) Erythronate-4-phosphate dehydrogenase (EC 1.... 38 6e-04
33SERA_RAT (O08651) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.9... 44 6e-04
34SERA_MOUSE (Q61753) D-3-phosphoglycerate dehydrogenase (EC 1.1.1... 44 6e-04
35SERA_HUMAN (O43175) D-3-phosphoglycerate dehydrogenase (EC 1.1.1... 44 6e-04
36SERA_BOVIN (Q5EAD2) D-3-phosphoglycerate dehydrogenase (EC 1.1.1... 44 6e-04
37SERA_PONPY (Q5R7M2) D-3-phosphoglycerate dehydrogenase (EC 1.1.1... 43 8e-04
38SERA_MACFA (Q60HD7) D-3-phosphoglycerate dehydrogenase (EC 1.1.1... 43 8e-04
39YPRB2_CORML (P0C1E9) Hypothetical protein in proB 3'region (EC 1... 33 0.001
40SERA_HAEIN (P43885) D-3-phosphoglycerate dehydrogenase (EC 1.1.1... 33 0.002
41PDXB_PSEPK (Q88L20) Erythronate-4-phosphate dehydrogenase (EC 1.... 34 0.002
42PDXB_VIBVY (Q7MIT6) Erythronate-4-phosphate dehydrogenase (EC 1.... 34 0.002
43PDXB_VIBVU (Q8DB36) Erythronate-4-phosphate dehydrogenase (EC 1.... 34 0.002
44CTBPA_XENLA (Q9YHU0) C-terminal-binding protein A (CtBP) 34 0.003
45CTBP1_MOUSE (O88712) C-terminal-binding protein 1 (EC 1.1.1.-) (... 34 0.003
46CTBP1_HUMAN (Q13363) C-terminal-binding protein 1 (EC 1.1.1.-) (... 34 0.003
47CTBP1_RAT (Q9Z2F5) C-terminal-binding protein 1 (EC 1.1.1.-) (Ct... 34 0.003
48PDXB_PSESM (Q884R9) Erythronate-4-phosphate dehydrogenase (EC 1.... 30 0.006
49PDXB_VIBCH (Q9KQ92) Erythronate-4-phosphate dehydrogenase (EC 1.... 35 0.008
50PDXB_PSEAE (Q9I3W9) Erythronate-4-phosphate dehydrogenase (EC 1.... 34 0.008
51SERA_SHIFL (P0A9T3) D-3-phosphoglycerate dehydrogenase (EC 1.1.1... 34 0.010
52SERA_ECOLI (P0A9T0) D-3-phosphoglycerate dehydrogenase (EC 1.1.1... 34 0.010
53SERA_ECOL6 (P0A9T1) D-3-phosphoglycerate dehydrogenase (EC 1.1.1... 34 0.010
54SERA_ECO57 (P0A9T2) D-3-phosphoglycerate dehydrogenase (EC 1.1.1... 34 0.010
55PDXB_VIBPA (Q87MN8) Erythronate-4-phosphate dehydrogenase (EC 1.... 35 0.013
56CTBPB_XENLA (Q9W758) C-terminal-binding protein B (TCF-3 corepre... 32 0.027
57LDHD_LACDE (P26297) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH... 29 0.027
58PDXB_WIGBR (Q8D2P6) Erythronate-4-phosphate dehydrogenase (EC 1.... 33 0.058
59LDHD_ECOLI (P52643) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH... 28 0.097
60PDXB_SALTY (P60802) Erythronate-4-phosphate dehydrogenase (EC 1.... 36 0.12
61PDXB_SALTI (P60801) Erythronate-4-phosphate dehydrogenase (EC 1.... 36 0.12
62VANH_ENTFC (Q05709) D-specific alpha-keto acid dehydrogenase (EC... 28 0.13
63DDH_ZYMMO (P30799) 2-hydroxyacid dehydrogenase homolog (EC 1.1.1.-) 30 0.21
64DDH_HAEIN (P44501) 2-hydroxyacid dehydrogenase homolog (EC 1.1.1.-) 27 0.27
65YGDH_SCHPO (O94574) Putative 2-hydroxyacid dehydrogenase C1773.1... 35 0.28
66PDXB_ECOL6 (Q8FFH2) Erythronate-4-phosphate dehydrogenase (EC 1.... 32 0.44
67VANH_ENTFA (Q47748) D-specific alpha-keto acid dehydrogenase (EC... 27 0.57
68PDXB_ERWCT (Q6D2N5) Erythronate-4-phosphate dehydrogenase (EC 1.... 33 0.61
69SERA_SCHPO (P87228) Putative D-3-phosphoglycerate dehydrogenase ... 27 0.71
70PDXB_SHIFL (Q83QR1) Erythronate-4-phosphate dehydrogenase (EC 1.... 31 0.72
71PDXB_ECO57 (Q8XCR0) Erythronate-4-phosphate dehydrogenase (EC 1.... 31 0.72
72Y2355_CORGL (P0C1E8) Hypothetical protein Cgl2355/cg2587 (EC 1.-... 33 1.0
73PDXB_YERPS (Q668W7) Erythronate-4-phosphate dehydrogenase (EC 1.... 32 1.8
74PDXB_YERPE (Q8D0U3) Erythronate-4-phosphate dehydrogenase (EC 1.... 32 1.8
75LDHD_LEUMC (P51011) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH... 25 2.0
76NIP7_YEAST (Q08962) 60S ribosome subunit biogenesis protein NIP7 31 3.1
77YP113_YEAST (Q02961) Putative 2-hydroxyacid dehydrogenase YPL113... 31 3.1
78PDXB_ECOLI (P05459) Erythronate-4-phosphate dehydrogenase (EC 1.... 29 3.3
79LDHD_TREPA (O83080) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH... 31 4.0
80LDHD_STAAW (Q8NUT2) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH... 31 4.0
81LDHD_STAAU (P72357) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH... 31 4.0
82LDHD_STAAS (Q6G6F1) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH... 31 4.0
83LDHD_STAAR (Q6GDS2) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH... 31 4.0
84LDHD_STAAN (P99116) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH... 31 4.0
85LDHD_STAAM (P63940) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH... 31 4.0
86LDHD_STAAC (Q5HD29) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH... 31 4.0
87CSN12_ASHGO (Q75BU2) COP9 signalosome complex subunit 12 30 5.2
88SERA_YEAST (P40054) D-3-phosphoglycerate dehydrogenase 1 (EC 1.1... 30 5.2
89SER33_YEAST (P40510) D-3-phosphoglycerate dehydrogenase 2 (EC 1.... 30 5.2
90LDHD_STAES (Q8CN22) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH... 30 6.8
91LDHD_STAEQ (Q5HLA0) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH... 30 6.8
92PDXB_SHEVI (Q56733) Erythronate-4-phosphate dehydrogenase (EC 1.... 30 8.9
93PDXB_SHEON (Q8ECR2) Erythronate-4-phosphate dehydrogenase (EC 1.... 30 8.9 
>DHGY_CUCSA (P13443) Glycerate dehydrogenase (EC 1.1.1.29) (NADH-dependent|
           hydroxypyruvate reductase) (HPR) (GDH)
          Length = 382

 Score =  193 bits (491), Expect(2) = 2e-58
 Identities = 91/107 (85%), Positives = 98/107 (91%)
 Frame = -2

Query: 579 GPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA 400
           GPVIDE ALV+HL+ NPMFRVGLDVFEDEPYMKPGLA+MKNA++VPHIASASKWTREGMA
Sbjct: 274 GPVIDEAALVDHLRDNPMFRVGLDVFEDEPYMKPGLADMKNAIIVPHIASASKWTREGMA 333

Query: 399 TLAALNVLGKIKGYPVWGNPNAVEPFLDEEATPPPACPSIVNAKQLG 259
           TLAALNVLGKIKGYPVW +PN VEPFLDE  +PP A PSIVNAK LG
Sbjct: 334 TLAALNVLGKIKGYPVWSDPNRVEPFLDENVSPPAASPSIVNAKALG 380



 Score = 52.8 bits (125), Expect(2) = 2e-58
 Identities = 23/36 (63%), Positives = 28/36 (77%)
 Frame = -1

Query: 682 ISLHPVLDKTTYHLINPERLAMMKKEAVLVNAKPWP 575
           ISLHPVLDKTT+HL+N E L  MKK+A+L+N    P
Sbjct: 240 ISLHPVLDKTTFHLVNKESLKAMKKDAILINCSRGP 275
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>GYAR_THELI (Q9C4M5) Glyoxylate reductase (EC 1.1.1.26) (Glycolate reductase)|
          Length = 331

 Score = 67.8 bits (164), Expect(2) = 4e-16
 Identities = 35/73 (47%), Positives = 46/73 (63%)
 Frame = -2

Query: 579 GPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA 400
           G V+D  AL++ LK   +   GLDVFE+EPY    L ++KN V+ PHI SA+   REGMA
Sbjct: 242 GAVVDTNALIKALKEGWIAGAGLDVFEEEPYYNEELFKLKNVVLAPHIGSATHEAREGMA 301

Query: 399 TLAALNVLGKIKG 361
            L A N++   KG
Sbjct: 302 ELVAKNLIAFAKG 314



 Score = 36.6 bits (83), Expect(2) = 4e-16
 Identities = 16/31 (51%), Positives = 21/31 (67%)
 Frame = -1

Query: 682 ISLHPVLDKTTYHLINPERLAMMKKEAVLVN 590
           ISLH  L K TYH+I  + L +MK  A+L+N
Sbjct: 208 ISLHVPLTKETYHMIGEKELKLMKPNAILIN 238
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>GYAR_PYRHO (O58320) Glyoxylate reductase (EC 1.1.1.26) (Glycolate reductase)|
          Length = 334

 Score = 64.7 bits (156), Expect(2) = 1e-15
 Identities = 35/73 (47%), Positives = 45/73 (61%)
 Frame = -2

Query: 579 GPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA 400
           G V+D  ALV+ LK   +   GLDVFE+EPY    L ++ N V+ PHI SAS   REGMA
Sbjct: 242 GKVVDTNALVKALKEGWIAGAGLDVFEEEPYYNEELFKLDNVVLTPHIGSASFGAREGMA 301

Query: 399 TLAALNVLGKIKG 361
            L A N++   +G
Sbjct: 302 ELVAKNLIAFKRG 314



 Score = 37.7 bits (86), Expect(2) = 1e-15
 Identities = 16/25 (64%), Positives = 20/25 (80%)
 Frame = -1

Query: 664 LDKTTYHLINPERLAMMKKEAVLVN 590
           L + TYHLIN ERL +MKK A+L+N
Sbjct: 214 LTRETYHLINEERLKLMKKTAILIN 238
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>GYAR_PYRAB (Q9UYR1) Glyoxylate reductase (EC 1.1.1.26) (Glycolate reductase)|
          Length = 335

 Score = 62.0 bits (149), Expect(2) = 4e-15
 Identities = 33/73 (45%), Positives = 44/73 (60%)
 Frame = -2

Query: 579 GPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA 400
           G VID  AL++ LK   +   GLDV+E+EPY    L  + N V+ PHI SA+   REGMA
Sbjct: 243 GKVIDTKALIKALKEGWIAGAGLDVYEEEPYYNEELFSLDNVVLTPHIGSATFGAREGMA 302

Query: 399 TLAALNVLGKIKG 361
            L A N++   +G
Sbjct: 303 KLVAENLIAFKRG 315



 Score = 38.9 bits (89), Expect(2) = 4e-15
 Identities = 16/25 (64%), Positives = 21/25 (84%)
 Frame = -1

Query: 664 LDKTTYHLINPERLAMMKKEAVLVN 590
           L+K TYH+IN ERL MMK+ A+L+N
Sbjct: 215 LNKETYHMINEERLKMMKRTAILIN 239
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>GYAR_PYRKO (Q5JEZ2) Glyoxylate reductase (EC 1.1.1.26) (Glycolate reductase)|
          Length = 333

 Score = 63.2 bits (152), Expect(2) = 9e-14
 Identities = 32/68 (47%), Positives = 43/68 (63%)
 Frame = -2

Query: 579 GPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA 400
           G V+D  AL++ LK   +   GLDV+E+EPY    L  +KN V+ PHI SA+   REGMA
Sbjct: 242 GKVVDTKALMKALKEGWIAGAGLDVYEEEPYYNEELFSLKNVVLAPHIGSATYGAREGMA 301

Query: 399 TLAALNVL 376
            L A N++
Sbjct: 302 ELVARNLI 309



 Score = 33.1 bits (74), Expect(2) = 9e-14
 Identities = 15/25 (60%), Positives = 19/25 (76%)
 Frame = -1

Query: 664 LDKTTYHLINPERLAMMKKEAVLVN 590
           L K T ++IN ERL +MKK A+LVN
Sbjct: 214 LTKETQYMINEERLRLMKKTAILVN 238
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>GYAR_PYRFU (Q8U3Y2) Glyoxylate reductase (EC 1.1.1.26) (Glycolate reductase)|
          Length = 336

 Score = 60.5 bits (145), Expect(2) = 3e-12
 Identities = 32/73 (43%), Positives = 43/73 (58%)
 Frame = -2

Query: 579 GPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA 400
           G V+D  AL++ LK   +   GLDVFE+EPY    L  + N V+ PHI SA+   RE MA
Sbjct: 242 GKVVDTKALIKALKEGWIAGAGLDVFEEEPYYNEELFSLDNVVLTPHIGSATFEAREAMA 301

Query: 399 TLAALNVLGKIKG 361
            L A N++   +G
Sbjct: 302 ELVARNLIAFKRG 314



 Score = 30.8 bits (68), Expect(2) = 3e-12
 Identities = 14/25 (56%), Positives = 18/25 (72%)
 Frame = -1

Query: 664 LDKTTYHLINPERLAMMKKEAVLVN 590
           L K T ++IN ERL +MK  A+LVN
Sbjct: 214 LTKETMYMINEERLKLMKPTAILVN 238
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>TKRA_ENTAG (P58000) 2-ketogluconate reductase (EC 1.1.1.215) (2KR)|
           (2-ketoaldonate reductase)
          Length = 323

 Score = 58.5 bits (140), Expect(2) = 8e-12
 Identities = 33/74 (44%), Positives = 43/74 (58%), Gaps = 1/74 (1%)
 Frame = -2

Query: 579 GPVIDEVALVEHLKANPMFRVGLDVFEDEPY-MKPGLAEMKNAVVVPHIASASKWTREGM 403
           GPV+DE AL+  LK   +   GLDVFE EP  +   L  + N V +PHI SA+  TR GM
Sbjct: 237 GPVVDEQALIAALKDKTIHAAGLDVFEQEPLPVDSELLTLPNVVALPHIGSATHETRYGM 296

Query: 402 ATLAALNVLGKIKG 361
           A  A  N++  + G
Sbjct: 297 ARDAVDNLIAALAG 310



 Score = 31.2 bits (69), Expect(2) = 8e-12
 Identities = 14/30 (46%), Positives = 20/30 (66%)
 Frame = -1

Query: 664 LDKTTYHLINPERLAMMKKEAVLVNAKPWP 575
           L + T+H+I  E+LA MK  A+L+NA   P
Sbjct: 209 LTEQTHHMIGREQLAKMKPSAILINAGRGP 238
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>TKRA_ECOLI (P37666) 2-ketogluconate reductase (EC 1.1.1.215) (2KR)|
           (2-ketoaldonate reductase)
          Length = 324

 Score = 61.6 bits (148), Expect(2) = 1e-11
 Identities = 34/74 (45%), Positives = 44/74 (59%), Gaps = 1/74 (1%)
 Frame = -2

Query: 579 GPVIDEVALVEHLKANPMFRVGLDVFEDEPY-MKPGLAEMKNAVVVPHIASASKWTREGM 403
           GPV+DE AL+  L+   +   GLDVFE EP  +   L  M N V VPHI SA+  TR GM
Sbjct: 238 GPVVDENALIAALQKGEIHAAGLDVFEQEPLSVDSPLLSMANVVAVPHIGSATHETRYGM 297

Query: 402 ATLAALNVLGKIKG 361
           A  A  N++  ++G
Sbjct: 298 AACAVDNLIDALQG 311



 Score = 27.7 bits (60), Expect(2) = 1e-11
 Identities = 13/32 (40%), Positives = 19/32 (59%)
 Frame = -1

Query: 670 PVLDKTTYHLINPERLAMMKKEAVLVNAKPWP 575
           P+ D+T +HL   E+ A MK  A+ +NA   P
Sbjct: 209 PLTDET-HHLFGAEQFAKMKSSAIFINAGRGP 239
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>TKRA_ECO57 (P58220) 2-ketogluconate reductase (EC 1.1.1.215) (2KR)|
           (2-ketoaldonate reductase)
          Length = 324

 Score = 61.6 bits (148), Expect(2) = 1e-11
 Identities = 34/74 (45%), Positives = 44/74 (59%), Gaps = 1/74 (1%)
 Frame = -2

Query: 579 GPVIDEVALVEHLKANPMFRVGLDVFEDEPY-MKPGLAEMKNAVVVPHIASASKWTREGM 403
           GPV+DE AL+  L+   +   GLDVFE EP  +   L  M N V VPHI SA+  TR GM
Sbjct: 238 GPVVDENALIAALQKGEIHAAGLDVFEQEPLSVDSPLLSMANVVAVPHIGSATHETRYGM 297

Query: 402 ATLAALNVLGKIKG 361
           A  A  N++  ++G
Sbjct: 298 AACAVDNLIDALQG 311



 Score = 27.7 bits (60), Expect(2) = 1e-11
 Identities = 13/32 (40%), Positives = 19/32 (59%)
 Frame = -1

Query: 670 PVLDKTTYHLINPERLAMMKKEAVLVNAKPWP 575
           P+ D+T +HL   E+ A MK  A+ +NA   P
Sbjct: 209 PLTDET-HHLFGAEQFAKMKSSAIFINAGRGP 239
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>GYAR_AERPE (Q9YAW4) Glyoxylate reductase (EC 1.1.1.26) (Glycolate reductase)|
          Length = 335

 Score = 51.6 bits (122), Expect(2) = 7e-10
 Identities = 31/75 (41%), Positives = 45/75 (60%), Gaps = 2/75 (2%)
 Frame = -2

Query: 579 GPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPG--LAEMKNAVVVPHIASASKWTREG 406
           G ++D  ALV+ L+   +    LDVFE+EP + P   L   KN V+ PH ASA++ TR  
Sbjct: 243 GAIVDTGALVKALREGWIAAAALDVFEEEP-LNPNHPLTAFKNVVLAPHAASATRETRLR 301

Query: 405 MATLAALNVLGKIKG 361
           MA +AA N++   +G
Sbjct: 302 MAMMAAENLVAFAQG 316



 Score = 31.6 bits (70), Expect(2) = 7e-10
 Identities = 15/31 (48%), Positives = 19/31 (61%)
 Frame = -1

Query: 682 ISLHPVLDKTTYHLINPERLAMMKKEAVLVN 590
           +S+H  L   T HLI    L +MKK A+LVN
Sbjct: 209 LSIHLPLTDETRHLIGESELKLMKKTAILVN 239
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>YEAA_SCHPO (O14075) Putative 2-hydroxyacid dehydrogenase UNK4.10 (EC 1.-.-.-)|
          Length = 334

 Score = 57.0 bits (136), Expect(2) = 9e-09
 Identities = 28/67 (41%), Positives = 41/67 (61%)
 Frame = -2

Query: 579 GPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA 400
           G V+DE ALVE L    ++  GLDVFE+EP + PGL E +  +++PH+ + S  T+  M 
Sbjct: 247 GAVMDEAALVEALDEGIVYSAGLDVFEEEPKIHPGLLENEKVILLPHLGTNSLETQYKME 306

Query: 399 TLAALNV 379
               +NV
Sbjct: 307 CAVLMNV 313



 Score = 22.3 bits (46), Expect(2) = 9e-09
 Identities = 11/31 (35%), Positives = 17/31 (54%)
 Frame = -1

Query: 682 ISLHPVLDKTTYHLINPERLAMMKKEAVLVN 590
           +SL+  L+  T H+I       MK+  V+VN
Sbjct: 213 LSLNLPLNAHTRHIIGKPEFQKMKRGIVIVN 243
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>SERA_METJA (Q58424) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)|
          Length = 524

 Score = 43.1 bits (100), Expect(2) = 3e-08
 Identities = 23/73 (31%), Positives = 38/73 (52%)
 Frame = -2

Query: 579 GPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA 400
           G +IDE AL E LK   +    LDVFE+EP     L  + N +  PH  ++++  ++   
Sbjct: 232 GGLIDEKALYEALKEGKIRAAALDVFEEEPPKDNPLLTLDNVIGTPHQGASTEEAQKAAG 291

Query: 399 TLAALNVLGKIKG 361
           T+ A  +   ++G
Sbjct: 292 TIVAEQIKKVLRG 304



 Score = 34.3 bits (77), Expect(2) = 3e-08
 Identities = 15/31 (48%), Positives = 22/31 (70%)
 Frame = -1

Query: 682 ISLHPVLDKTTYHLINPERLAMMKKEAVLVN 590
           I+LH  L   T H+I  E++A+MKK A++VN
Sbjct: 198 ITLHVPLTPKTRHIIGREQIALMKKNAIIVN 228
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>YN14_YEAST (P53839) Putative 2-hydroxyacid dehydrogenase YNL274C (EC 1.-.-.-)|
          Length = 350

 Score = 48.1 bits (113), Expect(2) = 3e-08
 Identities = 32/100 (32%), Positives = 47/100 (47%)
 Frame = -2

Query: 579 GPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA 400
           G VIDE A+ + L++  +   GLDVFE EP +   L  M   + +PH+ + S  TR+ M 
Sbjct: 255 GAVIDEQAMTDALRSGKIRSAGLDVFEYEPKISKELLSMSQVLGLPHMGTHSVETRKKME 314

Query: 399 TLAALNVLGKIKGYPVWGNPNAVEPFLDEEATPPPACPSI 280
            L   N     K   + G    + P L  E  P  + P +
Sbjct: 315 ELVVENA----KNVILTGKVLTIVPELQNEDWPNESKPLV 350



 Score = 29.3 bits (64), Expect(2) = 3e-08
 Identities = 13/31 (41%), Positives = 20/31 (64%)
 Frame = -1

Query: 682 ISLHPVLDKTTYHLINPERLAMMKKEAVLVN 590
           +S++  L+  T+HLIN E +  MK   V+VN
Sbjct: 221 VSVNVPLNHNTHHLINAETIEKMKDGVVIVN 251
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>SERA_ARATH (O04130) D-3-phosphoglycerate dehydrogenase, chloroplast precursor|
           (EC 1.1.1.95) (3-PGDH)
          Length = 624

 Score = 52.4 bits (124), Expect(2) = 4e-08
 Identities = 43/110 (39%), Positives = 58/110 (52%), Gaps = 3/110 (2%)
 Frame = -2

Query: 579 GPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPG-LAEMKNAVVVPHIASASKWTREGM 403
           G VIDE ALV  L A  + +  LDVF +EP  K   L + +N  V PH+ +++K  +EG+
Sbjct: 313 GGVIDEDALVRALDAGIVAQAALDVFCEEPPSKDSRLIQHENVTVTPHLGASTKEAQEGV 372

Query: 402 ATLAALNVLGKIKGYPVWGNPNA--VEPFLDEEATPPPACPSIVNAKQLG 259
           A   A  V G +KG       NA  V P +  E T     P IV A++LG
Sbjct: 373 AIEIAEAVAGALKGELSATAVNAPMVAPEVLSELT-----PYIVLAEKLG 417



 Score = 24.6 bits (52), Expect(2) = 4e-08
 Identities = 12/31 (38%), Positives = 16/31 (51%)
 Frame = -1

Query: 682 ISLHPVLDKTTYHLINPERLAMMKKEAVLVN 590
           +SLH  L   T  + N E  + MKK   L+N
Sbjct: 279 VSLHMPLTPATKKVFNDETFSKMKKGVRLIN 309
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>TKRA_BACSU (O32264) Probable 2-ketogluconate reductase (EC 1.1.1.215) (2KR)|
          Length = 325

 Score = 48.9 bits (115), Expect(2) = 2e-07
 Identities = 28/74 (37%), Positives = 41/74 (55%), Gaps = 1/74 (1%)
 Frame = -2

Query: 579 GPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPG-LAEMKNAVVVPHIASASKWTREGM 403
           G  +DE AL+  L+   +   GLDV+E EP  +   L ++ N  ++PHI SA+   R  M
Sbjct: 241 GKTVDEKALIRALQEGWIRGAGLDVYEKEPVTQDNPLLQLDNVTLLPHIGSATAKVRFNM 300

Query: 402 ATLAALNVLGKIKG 361
              AA N+L  I+G
Sbjct: 301 CKQAAENMLAAIQG 314



 Score = 25.8 bits (55), Expect(2) = 2e-07
 Identities = 11/27 (40%), Positives = 16/27 (59%)
 Frame = -1

Query: 670 PVLDKTTYHLINPERLAMMKKEAVLVN 590
           P+ D+T YH+I      +MK  A+ VN
Sbjct: 212 PLTDET-YHMIGEREFKLMKNSAIFVN 237
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>SERA_METTH (O27051) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)|
          Length = 525

 Score = 48.1 bits (113), Expect(2) = 3e-07
 Identities = 42/110 (38%), Positives = 56/110 (50%), Gaps = 3/110 (2%)
 Frame = -2

Query: 579 GPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHI-ASASKWTREGM 403
           G +IDE AL   LK   +    LDVFE+EP     L E++N V+ PHI AS S+  R+  
Sbjct: 233 GGIIDEDALYRALKDGEIAGAALDVFEEEPPEGSPLLELENVVLTPHIGASTSEAQRD-- 290

Query: 402 ATLAALNVLGKIKGYPVWGNPNAV--EPFLDEEATPPPACPSIVNAKQLG 259
              AA+ V  +IK     G P  V   P +D E T     P I  A+++G
Sbjct: 291 ---AAIIVANEIKTVFQGGAPRNVLNMPVMDSE-TYKSLKPYIELAEKMG 336



 Score = 26.2 bits (56), Expect(2) = 3e-07
 Identities = 11/31 (35%), Positives = 18/31 (58%)
 Frame = -1

Query: 682 ISLHPVLDKTTYHLINPERLAMMKKEAVLVN 590
           +++H  L   T HLI+ +   +MK  A +VN
Sbjct: 199 VTIHVPLTPETRHLISEDEFKLMKDTAFIVN 229
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>SERA_BACSU (P35136) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)|
          Length = 525

 Score = 47.0 bits (110), Expect(2) = 6e-07
 Identities = 31/95 (32%), Positives = 45/95 (47%)
 Frame = -2

Query: 579 GPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA 400
           G +IDE AL+E L+   +    LDVFE EP +   L +    +  PH+ +++K  +  +A
Sbjct: 230 GGIIDEAALLEALENGHVAGAALDVFEVEPPVDNKLVDHPLVIATPHLGASTKEAQLNVA 289

Query: 399 TLAALNVLGKIKGYPVWGNPNAVEPFLDEEATPPP 295
              +  VL   KG PV    N      DE A   P
Sbjct: 290 AQVSEEVLQFAKGLPVMSAINLPAMTKDEFAKIKP 324



 Score = 26.2 bits (56), Expect(2) = 6e-07
 Identities = 13/31 (41%), Positives = 18/31 (58%)
 Frame = -1

Query: 682 ISLHPVLDKTTYHLINPERLAMMKKEAVLVN 590
           I++H  L K T  L+N E +A  KK   L+N
Sbjct: 196 ITVHTPLTKETKGLLNKETIAKTKKGVRLIN 226
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>Y1556_HAEIN (P45250) Putative 2-hydroxyacid dehydrogenase HI1556 (EC 1.-.-.-)|
          Length = 315

 Score = 40.0 bits (92), Expect(2) = 7e-07
 Identities = 24/57 (42%), Positives = 30/57 (52%), Gaps = 5/57 (8%)
 Frame = -2

Query: 579 GPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKP-----GLAEMKNAVVVPHIASAS 424
           GP+IDE+ALV+ LK   +    LDV   EP  K          M N ++ PHIA AS
Sbjct: 234 GPLIDELALVDALKTGHLGGAALDVMVKEPPEKDNPLILAAKTMPNLIITPHIAWAS 290



 Score = 32.7 bits (73), Expect(2) = 7e-07
 Identities = 17/36 (47%), Positives = 22/36 (61%)
 Frame = -1

Query: 682 ISLHPVLDKTTYHLINPERLAMMKKEAVLVNAKPWP 575
           ++LH  L +TT  LIN E L+ MKK A L+N    P
Sbjct: 200 VTLHCPLTETTKDLINAETLSKMKKGAFLINTGRGP 235
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>DHGY_METEX (Q59516) Glycerate dehydrogenase (EC 1.1.1.29) (NADH-dependent|
           hydroxypyruvate reductase) (HPR) (GDH) (Hydroxypyruvate
           dehydrogenase) (Glyoxylate reductase) (HPR-A)
          Length = 313

 Score = 42.0 bits (97), Expect(2) = 3e-06
 Identities = 26/78 (33%), Positives = 39/78 (50%), Gaps = 3/78 (3%)
 Frame = -2

Query: 579 GPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGL---AEMKNAVVVPHIASASKWTRE 409
           G ++DE AL++ LK   +   G DV   EP     +   A++ N +V PH+A ASK   +
Sbjct: 230 GGLVDEAALLQALKDGTIGGAGFDVVAQEPPKDGNILCDADLPNLIVTPHVAWASKEAMQ 289

Query: 408 GMATLAALNVLGKIKGYP 355
            +A     NV   + G P
Sbjct: 290 ILADQLVDNVEAFVAGKP 307



 Score = 28.9 bits (63), Expect(2) = 3e-06
 Identities = 13/31 (41%), Positives = 20/31 (64%)
 Frame = -1

Query: 682 ISLHPVLDKTTYHLINPERLAMMKKEAVLVN 590
           I+LH  L   T ++I  E+L  MK+ A+L+N
Sbjct: 196 ITLHVPLTPDTKNMIGAEQLKKMKRSAILIN 226
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>SERA_ARCFU (O29445) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)|
          Length = 527

 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 29/88 (32%), Positives = 48/88 (54%), Gaps = 3/88 (3%)
 Frame = -2

Query: 579 GPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPG-LAEMKNAVVVPHIASASKWTREGM 403
           G ++DE AL E +KA  +    LDV+E EP      L ++ N V  PHIA++++  +  +
Sbjct: 231 GGIVDEAALYEAIKAGKVAAAALDVYEKEPPSPDNPLLKLDNVVTTPHIAASTREAQLNV 290

Query: 402 ATLAALNVLGKIKGYPVWGNPN--AVEP 325
             + A +++   KG PV    N  ++EP
Sbjct: 291 GMIIAEDIVNMAKGLPVRNAVNLPSIEP 318
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>GRHPR_HUMAN (Q9UBQ7) Glyoxylate reductase/hydroxypyruvate reductase (EC|
           1.1.1.79)
          Length = 328

 Score = 50.4 bits (119), Expect = 5e-06
 Identities = 29/77 (37%), Positives = 44/77 (57%), Gaps = 1/77 (1%)
 Frame = -2

Query: 579 GPVIDEVALVEHLKANPMFRVGLDVFEDEPY-MKPGLAEMKNAVVVPHIASASKWTREGM 403
           G V+++  L + L +  +   GLDV   EP      L  +KN V++PHI SA+  TR  M
Sbjct: 246 GDVVNQDDLYQALASGKIAAAGLDVTSPEPLPTNHPLLTLKNCVILPHIGSATHRTRNTM 305

Query: 402 ATLAALNVLGKIKGYPV 352
           + LAA N+L  ++G P+
Sbjct: 306 SLLAANNLLAGLRGEPM 322
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>SERA_SYNY3 (P73821) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)|
          Length = 554

 Score = 42.0 bits (97), Expect(2) = 2e-05
 Identities = 22/75 (29%), Positives = 38/75 (50%)
 Frame = -2

Query: 579 GPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA 400
           G +IDE ALV  ++   +    LDVF  EP  +  L E  N ++ PH+ ++++  +  +A
Sbjct: 259 GGIIDEEALVTAIETAQIGGAALDVFAQEPLGESRLREFSNVILTPHLGASTEEAQVNVA 318

Query: 399 TLAALNVLGKIKGYP 355
              A  +   + G P
Sbjct: 319 VDVAEQIRDVLLGLP 333



 Score = 25.8 bits (55), Expect(2) = 2e-05
 Identities = 14/31 (45%), Positives = 18/31 (58%)
 Frame = -1

Query: 682 ISLHPVLDKTTYHLINPERLAMMKKEAVLVN 590
           I+LH      T +LIN E LA MK  A ++N
Sbjct: 225 ITLHIPKTPETANLINAETLAKMKPTARIIN 255
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>SERA_MYCLE (O33116) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)|
          Length = 528

 Score = 45.1 bits (105), Expect(2) = 2e-05
 Identities = 28/93 (30%), Positives = 46/93 (49%)
 Frame = -2

Query: 579 GPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA 400
           G ++DEVAL + +++  +   GLDVF  EP     L E+   VV PH+ +++   ++   
Sbjct: 233 GGLVDEVALADAVRSGHVRAAGLDVFATEPCTDSPLFELSQVVVTPHLGASTAEAQDRAG 292

Query: 399 TLAALNVLGKIKGYPVWGNPNAVEPFLDEEATP 301
           T  A +V   + G  V    N     ++EE  P
Sbjct: 293 TDVAESVRLALAGEFVPDAVNVDGGVVNEEVAP 325



 Score = 22.7 bits (47), Expect(2) = 2e-05
 Identities = 13/32 (40%), Positives = 17/32 (53%)
 Frame = -1

Query: 682 ISLHPVLDKTTYHLINPERLAMMKKEAVLVNA 587
           IS+H      T  LI+ E LA  K   ++VNA
Sbjct: 199 ISVHLPKTPETAGLIDKEALAKTKPGVIIVNA 230
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>GRHPR_MOUSE (Q91Z53) Glyoxylate reductase/hydroxypyruvate reductase (EC|
           1.1.1.79)
          Length = 328

 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 29/75 (38%), Positives = 44/75 (58%), Gaps = 2/75 (2%)
 Frame = -2

Query: 579 GPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPG--LAEMKNAVVVPHIASASKWTREG 406
           G V+++  L + L +  +   GLDV   EP + P   L  +KN V++PHI SA+  TR  
Sbjct: 246 GDVVNQEDLYQALASGQIAAAGLDVTTPEP-LPPSHPLLTLKNCVILPHIGSATYKTRNT 304

Query: 405 MATLAALNVLGKIKG 361
           M+ LAA N+L  ++G
Sbjct: 305 MSLLAANNLLAGLRG 319
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>CTBP2_HUMAN (P56545) C-terminal-binding protein 2 (CtBP2)|
          Length = 445

 Score = 36.2 bits (82), Expect(2) = 1e-04
 Identities = 39/133 (29%), Positives = 56/133 (42%), Gaps = 22/133 (16%)
 Frame = -2

Query: 579 GPVIDEVALVEHLKANPMFRVGLDVFEDEP--YMKPGLAEMKNAVVVPHIA----SASKW 418
           G ++DE AL + LK   +    LDV E EP  + +  L +  N +  PH A     AS  
Sbjct: 273 GGLVDEKALAQALKEGRIRGAALDVHESEPFSFAQGPLKDAPNLICTPHTAWYSEQASLE 332

Query: 417 TREGMATLAALNVLGKI---------KGYPVWGNPNAVEPFLDEEATPPPA-------CP 286
            RE  AT     + G+I         K + V   P +V   +D++A  P          P
Sbjct: 333 MREAAATEIRRAITGRIPESLRNCVNKEFFVTSAPWSV---IDQQAIHPELNGATYRYPP 389

Query: 285 SIVNAKQLGLPSS 247
            IV     GLP++
Sbjct: 390 GIVGVAPGGLPAA 402



 Score = 29.3 bits (64), Expect(2) = 1e-04
 Identities = 14/32 (43%), Positives = 21/32 (65%)
 Frame = -1

Query: 682 ISLHPVLDKTTYHLINPERLAMMKKEAVLVNA 587
           +SLH  L++  +HLIN   +  M++ A LVNA
Sbjct: 239 VSLHCNLNEHNHHLINDFTIKQMRQGAFLVNA 270
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>CTBP2_MOUSE (P56546) C-terminal-binding protein 2 (CtBP2)|
          Length = 445

 Score = 35.8 bits (81), Expect(2) = 1e-04
 Identities = 26/77 (33%), Positives = 36/77 (46%), Gaps = 6/77 (7%)
 Frame = -2

Query: 579 GPVIDEVALVEHLKANPMFRVGLDVFEDEP--YMKPGLAEMKNAVVVPHIA----SASKW 418
           G ++DE AL + LK   +    LDV E EP  + +  L +  N +  PH A     AS  
Sbjct: 273 GGLVDEKALAQALKEGRIRGAALDVHESEPFSFAQGPLKDAPNLICTPHTAWYSEQASLE 332

Query: 417 TREGMATLAALNVLGKI 367
            RE  AT     + G+I
Sbjct: 333 MREAAATEIRRAITGRI 349



 Score = 29.3 bits (64), Expect(2) = 1e-04
 Identities = 14/32 (43%), Positives = 21/32 (65%)
 Frame = -1

Query: 682 ISLHPVLDKTTYHLINPERLAMMKKEAVLVNA 587
           +SLH  L++  +HLIN   +  M++ A LVNA
Sbjct: 239 VSLHCNLNEHNHHLINDFTIKQMRQGAFLVNA 270
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>SERA_MYCTU (P0A544) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)|
          Length = 528

 Score = 42.0 bits (97), Expect(2) = 2e-04
 Identities = 27/93 (29%), Positives = 43/93 (46%)
 Frame = -2

Query: 579 GPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA 400
           G ++DE AL + +    +   GLDVF  EP     L E+   VV PH+ +++   ++   
Sbjct: 233 GGLVDEAALADAITGGHVRAAGLDVFATEPCTDSPLFELAQVVVTPHLGASTAEAQDRAG 292

Query: 399 TLAALNVLGKIKGYPVWGNPNAVEPFLDEEATP 301
           T  A +V   + G  V    N     ++EE  P
Sbjct: 293 TDVAESVRLALAGEFVPDAVNVGGGVVNEEVAP 325



 Score = 22.7 bits (47), Expect(2) = 2e-04
 Identities = 13/32 (40%), Positives = 17/32 (53%)
 Frame = -1

Query: 682 ISLHPVLDKTTYHLINPERLAMMKKEAVLVNA 587
           IS+H      T  LI+ E LA  K   ++VNA
Sbjct: 199 ISVHLPKTPETAGLIDKEALAKTKPGVIIVNA 230
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>SERA_MYCBO (P0A545) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)|
          Length = 528

 Score = 42.0 bits (97), Expect(2) = 2e-04
 Identities = 27/93 (29%), Positives = 43/93 (46%)
 Frame = -2

Query: 579 GPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA 400
           G ++DE AL + +    +   GLDVF  EP     L E+   VV PH+ +++   ++   
Sbjct: 233 GGLVDEAALADAITGGHVRAAGLDVFATEPCTDSPLFELAQVVVTPHLGASTAEAQDRAG 292

Query: 399 TLAALNVLGKIKGYPVWGNPNAVEPFLDEEATP 301
           T  A +V   + G  V    N     ++EE  P
Sbjct: 293 TDVAESVRLALAGEFVPDAVNVGGGVVNEEVAP 325



 Score = 22.7 bits (47), Expect(2) = 2e-04
 Identities = 13/32 (40%), Positives = 17/32 (53%)
 Frame = -1

Query: 682 ISLHPVLDKTTYHLINPERLAMMKKEAVLVNA 587
           IS+H      T  LI+ E LA  K   ++VNA
Sbjct: 199 ISVHLPKTPETAGLIDKEALAKTKPGVIIVNA 230
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>PTXD_PSEST (O69054) Phosphonate dehydrogenase (EC 1.20.1.1) (NAD-dependent|
           phosphite dehydrogenase)
          Length = 336

 Score = 37.0 bits (84), Expect(2) = 2e-04
 Identities = 24/81 (29%), Positives = 37/81 (45%), Gaps = 8/81 (9%)
 Frame = -2

Query: 579 GPVIDEVALVEHLKANPMFRVGLDVFEDEPYMK--------PGLAEMKNAVVVPHIASAS 424
           G V+DE A++  L+   +     DVFE E + +        P L    N +  PHI SA 
Sbjct: 238 GSVVDEAAVLAALERGQLGGYAADVFEMEDWARADRPRLIDPALLAHPNTLFTPHIGSAV 297

Query: 423 KWTREGMATLAALNVLGKIKG 361
           +  R  +   AA N++  + G
Sbjct: 298 RAVRLEIERCAAQNIIQVLAG 318



 Score = 27.3 bits (59), Expect(2) = 2e-04
 Identities = 12/25 (48%), Positives = 18/25 (72%)
 Frame = -1

Query: 664 LDKTTYHLINPERLAMMKKEAVLVN 590
           L+  T HL+N E LA+++  A+LVN
Sbjct: 210 LNADTQHLVNAELLALVRPGALLVN 234
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>DHGY_HYPME (P36234) Glycerate dehydrogenase (EC 1.1.1.29) (NADH-dependent|
           hydroxypyruvate reductase) (HPR) (GDH) (Hydroxypyruvate
           dehydrogenase) (Glyoxylate reductase)
          Length = 321

 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 22/60 (36%), Positives = 32/60 (53%)
 Frame = -2

Query: 579 GPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA 400
           G ++D   +V  L+A  +   G DVF  EP +  G  ++ N  + PHI SA+   RE MA
Sbjct: 241 GDLVDNELVVAALEAGRLAYAGFDVFAGEPNINEGYYDLPNTFLFPHIGSAATQAREDMA 300
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>CTBP_DROME (O46036) C-terminal-binding protein (CtBP protein) (dCtBP)|
          Length = 476

 Score = 35.0 bits (79), Expect(2) = 4e-04
 Identities = 30/108 (27%), Positives = 47/108 (43%), Gaps = 5/108 (4%)
 Frame = -2

Query: 579 GPVIDEVALVEHLKANPMFRVGLDVFEDEPY--MKPGLAEMKNAVVVPHIASASKWTREG 406
           G ++D+  L   LK   +    LDV E+EPY   +  L +  N +  PH A  S  +   
Sbjct: 267 GGLVDDETLALALKQGRIRAAALDVHENEPYNVFQGALKDAPNLICTPHAAFFSDASATE 326

Query: 405 MATLAALNVLGKIKGYPVWGNPNAVEPFLDEE---ATPPPACPSIVNA 271
           +  +AA  +   I G      P+ +   +++E    TPP A    V A
Sbjct: 327 LREMAATEIRRAIVG----NIPDVLRNCVNKEYFMRTPPAAAAGGVAA 370



 Score = 28.1 bits (61), Expect(2) = 4e-04
 Identities = 13/31 (41%), Positives = 19/31 (61%)
 Frame = -1

Query: 682 ISLHPVLDKTTYHLINPERLAMMKKEAVLVN 590
           +SLH  L++  +HLIN   +  M+  A LVN
Sbjct: 233 VSLHCTLNEHNHHLINEFTIKQMRPGAFLVN 263
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>PDXB_PHOLL (Q7N2B2) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)|
          Length = 375

 Score = 37.7 bits (86), Expect(2) = 6e-04
 Identities = 26/60 (43%), Positives = 33/60 (55%)
 Frame = -2

Query: 579 GPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA 400
           G VID  AL+  LK     RV LDV+E EP +   L E+ + +  PHIA    +T EG A
Sbjct: 209 GEVIDNQALLTALKCGKKLRVVLDVWEPEPDLSLPLLELVD-IGTPHIAG---YTLEGKA 264



 Score = 25.0 bits (53), Expect(2) = 6e-04
 Identities = 11/36 (30%), Positives = 23/36 (63%), Gaps = 4/36 (11%)
 Frame = -1

Query: 682 ISLHPVLDKT----TYHLINPERLAMMKKEAVLVNA 587
           ++ H  L+K+    T+HL++ E L+++    +L+NA
Sbjct: 171 LTFHTPLNKSGPYKTHHLVDVELLSVLPDNRILINA 206
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>SERA_RAT (O08651) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (3-PGDH)|
          Length = 532

 Score = 43.5 bits (101), Expect = 6e-04
 Identities = 23/82 (28%), Positives = 41/82 (50%)
 Frame = -2

Query: 579 GPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA 400
           G ++DE AL+  L++       LDVF +EP     L + +N +  PH+ +++K  +    
Sbjct: 236 GGIVDEGALLRALQSGQCAGAALDVFTEEPPRDRALVDHENVISCPHLGASTKEAQSRCG 295

Query: 399 TLAALNVLGKIKGYPVWGNPNA 334
              A+  +  +KG  + G  NA
Sbjct: 296 EEIAVQFVDMVKGKSLTGVVNA 317
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>SERA_MOUSE (Q61753) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (3-PGDH)|
           (A10)
          Length = 532

 Score = 43.5 bits (101), Expect = 6e-04
 Identities = 23/82 (28%), Positives = 41/82 (50%)
 Frame = -2

Query: 579 GPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA 400
           G ++DE AL+  L++       LDVF +EP     L + +N +  PH+ +++K  +    
Sbjct: 236 GGIVDEGALLRALQSGQCAGAALDVFTEEPPRDRALVDHENVISCPHLGASTKEAQSRCG 295

Query: 399 TLAALNVLGKIKGYPVWGNPNA 334
              A+  +  +KG  + G  NA
Sbjct: 296 EEIAVQFVDMVKGKSLTGVVNA 317
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>SERA_HUMAN (O43175) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (3-PGDH)|
          Length = 532

 Score = 43.5 bits (101), Expect = 6e-04
 Identities = 23/82 (28%), Positives = 41/82 (50%)
 Frame = -2

Query: 579 GPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA 400
           G ++DE AL+  L++       LDVF +EP     L + +N +  PH+ +++K  +    
Sbjct: 236 GGIVDEGALLRALQSGQCAGAALDVFTEEPPRDRALVDHENVISCPHLGASTKEAQSRCG 295

Query: 399 TLAALNVLGKIKGYPVWGNPNA 334
              A+  +  +KG  + G  NA
Sbjct: 296 EEIAVQFVDMVKGKSLTGVVNA 317
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>SERA_BOVIN (Q5EAD2) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (3-PGDH)|
          Length = 532

 Score = 43.5 bits (101), Expect = 6e-04
 Identities = 24/82 (29%), Positives = 40/82 (48%)
 Frame = -2

Query: 579 GPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA 400
           G ++DE AL+  L++       LDVF +EP     L   +N +  PH+ +++K  +    
Sbjct: 236 GGIVDEGALLRALQSGQCAGAALDVFTEEPPRDRALVNHENVISCPHLGASTKEAQSRCG 295

Query: 399 TLAALNVLGKIKGYPVWGNPNA 334
              AL  +  +KG  + G  NA
Sbjct: 296 EEIALQFVDMVKGKALAGVVNA 317
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>SERA_PONPY (Q5R7M2) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (3-PGDH)|
          Length = 532

 Score = 43.1 bits (100), Expect = 8e-04
 Identities = 23/82 (28%), Positives = 41/82 (50%)
 Frame = -2

Query: 579 GPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA 400
           G ++DE AL+  L++       LDVF +EP     L + +N +  PH+ +++K  +    
Sbjct: 236 GGIVDEGALLRALQSGQCAGAALDVFTEEPPRGRALVDHENVISCPHLGASTKEAQSRCG 295

Query: 399 TLAALNVLGKIKGYPVWGNPNA 334
              A+  +  +KG  + G  NA
Sbjct: 296 EEIAVQFVDMVKGKSLTGVVNA 317
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>SERA_MACFA (Q60HD7) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (3-PGDH)|
          Length = 532

 Score = 43.1 bits (100), Expect = 8e-04
 Identities = 23/82 (28%), Positives = 41/82 (50%)
 Frame = -2

Query: 579 GPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA 400
           G ++DE AL+  L++       LDVF +EP     L + +N +  PH+ +++K  +    
Sbjct: 236 GGIVDEGALLRALQSGQCAGAALDVFTEEPPRDRALVDHENVISCPHLGASTKEAQSRCG 295

Query: 399 TLAALNVLGKIKGYPVWGNPNA 334
              A+  +  +KG  + G  NA
Sbjct: 296 EEIAVQFVDMVKGKSLAGVVNA 317
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>YPRB2_CORML (P0C1E9) Hypothetical protein in proB 3'region (EC 1.-.-.-)|
          Length = 304

 Score = 32.7 bits (73), Expect(2) = 0.001
 Identities = 22/68 (32%), Positives = 32/68 (47%), Gaps = 1/68 (1%)
 Frame = -2

Query: 579 GPVIDEVALVEHLKANPMFRVGLDVFEDEPYM-KPGLAEMKNAVVVPHIASASKWTREGM 403
           GP+I+   LV+ L    +    LDV + EP      L EM N V+ PH A+ ++  R   
Sbjct: 218 GPLINTDDLVDALNNGTIAGAALDVTDPEPLPDSHPLWEMDNVVITPHTANTNERIRALT 277

Query: 402 ATLAALNV 379
             L   N+
Sbjct: 278 GELTLRNI 285



 Score = 28.9 bits (63), Expect(2) = 0.001
 Identities = 14/30 (46%), Positives = 16/30 (53%)
 Frame = -1

Query: 664 LDKTTYHLINPERLAMMKKEAVLVNAKPWP 575
           L   TY ++N E L  MK  AVLVN    P
Sbjct: 190 LTDATYQIVNAETLGKMKPSAVLVNVGRGP 219
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>SERA_HAEIN (P43885) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)|
          Length = 410

 Score = 33.1 bits (74), Expect(2) = 0.002
 Identities = 24/80 (30%), Positives = 36/80 (45%), Gaps = 6/80 (7%)
 Frame = -2

Query: 579 GPVIDEVALVEHLKANPMFRVGLDVFEDEP------YMKPGLAEMKNAVVVPHIASASKW 418
           G V+D  AL + LK   +    +DVF  EP      ++ P L E  N ++ PHI  ++  
Sbjct: 242 GTVVDIDALAQALKDGKLQGAAIDVFPVEPASINEEFISP-LREFDNVILTPHIGGSTAE 300

Query: 417 TREGMATLAALNVLGKIKGY 358
            +E +       V GK   Y
Sbjct: 301 AQENI----GFEVAGKFVKY 316



 Score = 28.1 bits (61), Expect(2) = 0.002
 Identities = 13/32 (40%), Positives = 22/32 (68%)
 Frame = -1

Query: 682 ISLHPVLDKTTYHLINPERLAMMKKEAVLVNA 587
           +SLH     +T +L+N  R+A +K+ A+L+NA
Sbjct: 208 VSLHVPELPSTKNLMNVARIAQLKQGAILINA 239
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>PDXB_PSEPK (Q88L20) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)|
          Length = 380

 Score = 34.3 bits (77), Expect(2) = 0.002
 Identities = 22/52 (42%), Positives = 28/52 (53%)
 Frame = -2

Query: 579 GPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASAS 424
           GPV+D VAL E L         LDV+E EP +   LA++   +  PHIA  S
Sbjct: 208 GPVVDNVALRELLLDREDVHAVLDVWEGEPQVDLQLADL-CTLATPHIAGYS 258



 Score = 26.9 bits (58), Expect(2) = 0.002
 Identities = 16/40 (40%), Positives = 22/40 (55%), Gaps = 4/40 (10%)
 Frame = -1

Query: 682 ISLHPVLDK----TTYHLINPERLAMMKKEAVLVNAKPWP 575
           ISLH  L +     T+HL+   +LA ++  A LVNA   P
Sbjct: 170 ISLHTPLQRGGQHPTWHLLGQAQLAQLRPGAWLVNASRGP 209
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>PDXB_VIBVY (Q7MIT6) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)|
          Length = 377

 Score = 33.9 bits (76), Expect(2) = 0.002
 Identities = 20/49 (40%), Positives = 25/49 (51%)
 Frame = -2

Query: 579 GPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIA 433
           GPV+D  AL   L+    F   LDVFE EP +   L  +  A   PH+A
Sbjct: 210 GPVVDNQALKHRLQQADGFTAALDVFEFEPEVDMELLPLL-AFATPHVA 257



 Score = 26.9 bits (58), Expect(2) = 0.002
 Identities = 14/40 (35%), Positives = 23/40 (57%), Gaps = 4/40 (10%)
 Frame = -1

Query: 682 ISLHPVLDKT----TYHLINPERLAMMKKEAVLVNAKPWP 575
           I+LH  + +     T+HLIN E L  ++ + +L+NA   P
Sbjct: 172 ITLHTPITRDGKYPTHHLINKEILNSLRADQILINAARGP 211
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>PDXB_VIBVU (Q8DB36) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)|
          Length = 377

 Score = 33.9 bits (76), Expect(2) = 0.002
 Identities = 20/49 (40%), Positives = 25/49 (51%)
 Frame = -2

Query: 579 GPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIA 433
           GPV+D  AL   L+    F   LDVFE EP +   L  +  A   PH+A
Sbjct: 210 GPVVDNQALKRRLQQADGFMAALDVFEFEPEVDMELLPLL-AFATPHVA 257



 Score = 26.9 bits (58), Expect(2) = 0.002
 Identities = 14/40 (35%), Positives = 23/40 (57%), Gaps = 4/40 (10%)
 Frame = -1

Query: 682 ISLHPVLDKT----TYHLINPERLAMMKKEAVLVNAKPWP 575
           I+LH  + +     T+HLIN E L  ++ + +L+NA   P
Sbjct: 172 ITLHTPITRDGKYPTHHLINEEILNSLRADQILINAARGP 211
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>CTBPA_XENLA (Q9YHU0) C-terminal-binding protein A (CtBP)|
          Length = 440

 Score = 33.9 bits (76), Expect(2) = 0.003
 Identities = 24/75 (32%), Positives = 34/75 (45%), Gaps = 2/75 (2%)
 Frame = -2

Query: 579 GPVIDEVALVEHLKANPMFRVGLDVFEDEP--YMKPGLAEMKNAVVVPHIASASKWTREG 406
           G ++DE AL + LK   +    LDV E EP  + +  L +  N +  PH A  S+     
Sbjct: 267 GGLVDEKALAQALKEGRIRGAALDVHESEPFSFTQGPLKDAPNLICTPHAAWYSEQASIE 326

Query: 405 MATLAALNVLGKIKG 361
           M   AA  +   I G
Sbjct: 327 MREEAAREIRRAITG 341



 Score = 26.6 bits (57), Expect(2) = 0.003
 Identities = 12/31 (38%), Positives = 20/31 (64%)
 Frame = -1

Query: 682 ISLHPVLDKTTYHLINPERLAMMKKEAVLVN 590
           ++LH  L++  +HLIN   +  M++ A LVN
Sbjct: 233 VTLHCGLNEHNHHLINDFTIKQMRQGAFLVN 263
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>CTBP1_MOUSE (O88712) C-terminal-binding protein 1 (EC 1.1.1.-) (CtBP1)|
          Length = 440

 Score = 33.9 bits (76), Expect(2) = 0.003
 Identities = 24/75 (32%), Positives = 34/75 (45%), Gaps = 2/75 (2%)
 Frame = -2

Query: 579 GPVIDEVALVEHLKANPMFRVGLDVFEDEP--YMKPGLAEMKNAVVVPHIASASKWTREG 406
           G ++DE AL + LK   +    LDV E EP  + +  L +  N +  PH A  S+     
Sbjct: 267 GGLVDEKALAQALKEGRIRGAALDVHESEPFSFSQGPLKDAPNLICTPHAAWYSEQASIE 326

Query: 405 MATLAALNVLGKIKG 361
           M   AA  +   I G
Sbjct: 327 MREEAAREIRRAITG 341



 Score = 26.2 bits (56), Expect(2) = 0.003
 Identities = 12/31 (38%), Positives = 20/31 (64%)
 Frame = -1

Query: 682 ISLHPVLDKTTYHLINPERLAMMKKEAVLVN 590
           ++LH  L++  +HLIN   +  M++ A LVN
Sbjct: 233 VTLHCGLNEHNHHLINDFTVKQMRQGAFLVN 263
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>CTBP1_HUMAN (Q13363) C-terminal-binding protein 1 (EC 1.1.1.-) (CtBP1)|
          Length = 440

 Score = 33.9 bits (76), Expect(2) = 0.003
 Identities = 24/75 (32%), Positives = 34/75 (45%), Gaps = 2/75 (2%)
 Frame = -2

Query: 579 GPVIDEVALVEHLKANPMFRVGLDVFEDEP--YMKPGLAEMKNAVVVPHIASASKWTREG 406
           G ++DE AL + LK   +    LDV E EP  + +  L +  N +  PH A  S+     
Sbjct: 267 GGLVDEKALAQALKEGRIRGAALDVHESEPFSFSQGPLKDAPNLICTPHAAWYSEQASIE 326

Query: 405 MATLAALNVLGKIKG 361
           M   AA  +   I G
Sbjct: 327 MREEAAREIRRAITG 341



 Score = 26.2 bits (56), Expect(2) = 0.003
 Identities = 12/31 (38%), Positives = 20/31 (64%)
 Frame = -1

Query: 682 ISLHPVLDKTTYHLINPERLAMMKKEAVLVN 590
           ++LH  L++  +HLIN   +  M++ A LVN
Sbjct: 233 VTLHCGLNEHNHHLINDFTVKQMRQGAFLVN 263
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>CTBP1_RAT (Q9Z2F5) C-terminal-binding protein 1 (EC 1.1.1.-) (CtBP1)|
           (C-terminal-binding protein 3) (CtBP3) (50 kDa
           BFA-dependent ADP-ribosylation substrate) (BARS-50)
          Length = 430

 Score = 33.9 bits (76), Expect(2) = 0.003
 Identities = 24/75 (32%), Positives = 34/75 (45%), Gaps = 2/75 (2%)
 Frame = -2

Query: 579 GPVIDEVALVEHLKANPMFRVGLDVFEDEP--YMKPGLAEMKNAVVVPHIASASKWTREG 406
           G ++DE AL + LK   +    LDV E EP  + +  L +  N +  PH A  S+     
Sbjct: 256 GGLVDEKALAQALKEGRIRGAALDVHESEPFSFSQGPLKDAPNLICTPHAAWYSEQASIE 315

Query: 405 MATLAALNVLGKIKG 361
           M   AA  +   I G
Sbjct: 316 MREEAAREIRRAITG 330



 Score = 26.2 bits (56), Expect(2) = 0.003
 Identities = 12/31 (38%), Positives = 20/31 (64%)
 Frame = -1

Query: 682 ISLHPVLDKTTYHLINPERLAMMKKEAVLVN 590
           ++LH  L++  +HLIN   +  M++ A LVN
Sbjct: 222 VTLHCGLNEHNHHLINDFTVKQMRQGAFLVN 252
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>PDXB_PSESM (Q884R9) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)|
          Length = 380

 Score = 30.4 bits (67), Expect(2) = 0.006
 Identities = 16/36 (44%), Positives = 24/36 (66%), Gaps = 4/36 (11%)
 Frame = -1

Query: 682 ISLHPVLDKT----TYHLINPERLAMMKKEAVLVNA 587
           ISLH  LDK+    T+HL++  RL  +++ A L+NA
Sbjct: 170 ISLHTPLDKSGQSPTWHLLDEARLRQLRQGAWLINA 205



 Score = 28.9 bits (63), Expect(2) = 0.006
 Identities = 18/52 (34%), Positives = 27/52 (51%)
 Frame = -2

Query: 579 GPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASAS 424
           G V+D  AL + +      +  LDV+E EP +   LA++   +  PHIA  S
Sbjct: 208 GAVVDNRALHDVMLEREDLQAVLDVWEGEPQVNVALADL-CVIGTPHIAGYS 258
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>PDXB_VIBCH (Q9KQ92) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)|
          Length = 381

 Score = 35.0 bits (79), Expect(2) = 0.008
 Identities = 30/87 (34%), Positives = 38/87 (43%), Gaps = 2/87 (2%)
 Frame = -2

Query: 579 GPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA 400
           GPV+D  AL   L+    F   LDVFE EP +   L  +  A   PHIA    +  EG A
Sbjct: 210 GPVVDNAALKARLQQGDGFTAVLDVFEFEPQVDMELLPLL-AFATPHIAG---YGLEGKA 265

Query: 399 --TLAALNVLGKIKGYPVWGNPNAVEP 325
             T    N   +  G     NP ++ P
Sbjct: 266 RGTTMIFNSYCEFLGSAHCANPASLLP 292



 Score = 23.9 bits (50), Expect(2) = 0.008
 Identities = 12/40 (30%), Positives = 22/40 (55%), Gaps = 4/40 (10%)
 Frame = -1

Query: 682 ISLHPVLDK----TTYHLINPERLAMMKKEAVLVNAKPWP 575
           I+LH  + +     T+HLI+   L  ++ + +L+NA   P
Sbjct: 172 ITLHTPITRGGEWPTHHLIDAAILEQLRSDQILINAARGP 211
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>PDXB_PSEAE (Q9I3W9) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)|
          Length = 380

 Score = 34.3 bits (77), Expect(2) = 0.008
 Identities = 21/52 (40%), Positives = 26/52 (50%)
 Frame = -2

Query: 579 GPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASAS 424
           G V+D  AL   L+      V LDV+E EP   P LA  +  +  PHIA  S
Sbjct: 209 GAVVDNQALRRLLEGGADLEVALDVWEGEPQADPELA-ARCLIATPHIAGYS 259



 Score = 24.6 bits (52), Expect(2) = 0.008
 Identities = 15/36 (41%), Positives = 21/36 (58%), Gaps = 4/36 (11%)
 Frame = -1

Query: 682 ISLHPVLDKT----TYHLINPERLAMMKKEAVLVNA 587
           ISLH  L++     T HL++  RLA ++    LVNA
Sbjct: 171 ISLHTPLNRDGEHPTRHLLDEPRLAALRPGTWLVNA 206
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>SERA_SHIFL (P0A9T3) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)|
          Length = 409

 Score = 34.3 bits (77), Expect(2) = 0.010
 Identities = 24/80 (30%), Positives = 38/80 (47%), Gaps = 6/80 (7%)
 Frame = -2

Query: 579 GPVIDEVALVEHLKANPMFRVGLDVFEDE------PYMKPGLAEMKNAVVVPHIASASKW 418
           G V+D  AL + L +  +    +DVF  E      P+  P L E  N ++ PHI  +++ 
Sbjct: 240 GTVVDIPALCDALASKHLAGAAIDVFPTEPATNSDPFTSP-LCEFDNVLLTPHIGGSTQE 298

Query: 417 TREGMATLAALNVLGKIKGY 358
            +E +     L V GK+  Y
Sbjct: 299 AQENI----GLEVAGKLIKY 314



 Score = 24.3 bits (51), Expect(2) = 0.010
 Identities = 9/32 (28%), Positives = 22/32 (68%)
 Frame = -1

Query: 682 ISLHPVLDKTTYHLINPERLAMMKKEAVLVNA 587
           +SLH   + +T +++  + +++MK  ++L+NA
Sbjct: 206 VSLHVPENPSTKNMMGAKEISLMKPGSLLINA 237
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>SERA_ECOLI (P0A9T0) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)|
          Length = 409

 Score = 34.3 bits (77), Expect(2) = 0.010
 Identities = 24/80 (30%), Positives = 38/80 (47%), Gaps = 6/80 (7%)
 Frame = -2

Query: 579 GPVIDEVALVEHLKANPMFRVGLDVFEDE------PYMKPGLAEMKNAVVVPHIASASKW 418
           G V+D  AL + L +  +    +DVF  E      P+  P L E  N ++ PHI  +++ 
Sbjct: 240 GTVVDIPALCDALASKHLAGAAIDVFPTEPATNSDPFTSP-LCEFDNVLLTPHIGGSTQE 298

Query: 417 TREGMATLAALNVLGKIKGY 358
            +E +     L V GK+  Y
Sbjct: 299 AQENI----GLEVAGKLIKY 314



 Score = 24.3 bits (51), Expect(2) = 0.010
 Identities = 9/32 (28%), Positives = 22/32 (68%)
 Frame = -1

Query: 682 ISLHPVLDKTTYHLINPERLAMMKKEAVLVNA 587
           +SLH   + +T +++  + +++MK  ++L+NA
Sbjct: 206 VSLHVPENPSTKNMMGAKEISLMKPGSLLINA 237
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>SERA_ECOL6 (P0A9T1) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)|
          Length = 409

 Score = 34.3 bits (77), Expect(2) = 0.010
 Identities = 24/80 (30%), Positives = 38/80 (47%), Gaps = 6/80 (7%)
 Frame = -2

Query: 579 GPVIDEVALVEHLKANPMFRVGLDVFEDE------PYMKPGLAEMKNAVVVPHIASASKW 418
           G V+D  AL + L +  +    +DVF  E      P+  P L E  N ++ PHI  +++ 
Sbjct: 240 GTVVDIPALCDALASKHLAGAAIDVFPTEPATNSDPFTSP-LCEFDNVLLTPHIGGSTQE 298

Query: 417 TREGMATLAALNVLGKIKGY 358
            +E +     L V GK+  Y
Sbjct: 299 AQENI----GLEVAGKLIKY 314



 Score = 24.3 bits (51), Expect(2) = 0.010
 Identities = 9/32 (28%), Positives = 22/32 (68%)
 Frame = -1

Query: 682 ISLHPVLDKTTYHLINPERLAMMKKEAVLVNA 587
           +SLH   + +T +++  + +++MK  ++L+NA
Sbjct: 206 VSLHVPENPSTKNMMGAKEISLMKPGSLLINA 237
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>SERA_ECO57 (P0A9T2) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)|
          Length = 409

 Score = 34.3 bits (77), Expect(2) = 0.010
 Identities = 24/80 (30%), Positives = 38/80 (47%), Gaps = 6/80 (7%)
 Frame = -2

Query: 579 GPVIDEVALVEHLKANPMFRVGLDVFEDE------PYMKPGLAEMKNAVVVPHIASASKW 418
           G V+D  AL + L +  +    +DVF  E      P+  P L E  N ++ PHI  +++ 
Sbjct: 240 GTVVDIPALCDALASKHLAGAAIDVFPTEPATNSDPFTSP-LCEFDNVLLTPHIGGSTQE 298

Query: 417 TREGMATLAALNVLGKIKGY 358
            +E +     L V GK+  Y
Sbjct: 299 AQENI----GLEVAGKLIKY 314



 Score = 24.3 bits (51), Expect(2) = 0.010
 Identities = 9/32 (28%), Positives = 22/32 (68%)
 Frame = -1

Query: 682 ISLHPVLDKTTYHLINPERLAMMKKEAVLVNA 587
           +SLH   + +T +++  + +++MK  ++L+NA
Sbjct: 206 VSLHVPENPSTKNMMGAKEISLMKPGSLLINA 237
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>PDXB_VIBPA (Q87MN8) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)|
          Length = 377

 Score = 34.7 bits (78), Expect(2) = 0.013
 Identities = 20/49 (40%), Positives = 25/49 (51%)
 Frame = -2

Query: 579 GPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIA 433
           GPV+D  AL + L     F   LDVFE EP +   L  +  A   PH+A
Sbjct: 210 GPVVDNQALKQRLMKQDGFTAALDVFEFEPEVDMELLPLL-AFATPHVA 257



 Score = 23.5 bits (49), Expect(2) = 0.013
 Identities = 13/40 (32%), Positives = 23/40 (57%), Gaps = 4/40 (10%)
 Frame = -1

Query: 682 ISLHPVLDKT----TYHLINPERLAMMKKEAVLVNAKPWP 575
           I+LH  + K     T+HLI+ + L  ++ + +L+NA   P
Sbjct: 172 ITLHTPITKDGLHPTHHLIDEKVLNGLRGDQILINAARGP 211
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>CTBPB_XENLA (Q9W758) C-terminal-binding protein B (TCF-3 corepressor CtBP)|
           (XCtBP)
          Length = 437

 Score = 31.6 bits (70), Expect(2) = 0.027
 Identities = 18/51 (35%), Positives = 26/51 (50%), Gaps = 2/51 (3%)
 Frame = -2

Query: 579 GPVIDEVALVEHLKANPMFRVGLDVFEDEP--YMKPGLAEMKNAVVVPHIA 433
           G ++DE AL + LK   +    LDV E EP  + +  L +  N +  PH A
Sbjct: 270 GGLVDEKALAQALKDGRIRGAALDVHESEPFSFSQGPLKDAPNLICTPHTA 320



 Score = 25.4 bits (54), Expect(2) = 0.027
 Identities = 12/31 (38%), Positives = 19/31 (61%)
 Frame = -1

Query: 682 ISLHPVLDKTTYHLINPERLAMMKKEAVLVN 590
           I+LH  L++  +HLIN   +  M++   LVN
Sbjct: 236 ITLHCNLNEHNHHLINDFTIKQMRQGCFLVN 266
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>LDHD_LACDE (P26297) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific|
           D-2-hydroxyacid dehydrogenase)
          Length = 332

 Score = 28.9 bits (63), Expect(2) = 0.027
 Identities = 14/36 (38%), Positives = 20/36 (55%)
 Frame = -1

Query: 682 ISLHPVLDKTTYHLINPERLAMMKKEAVLVNAKPWP 575
           ISLH        H+IN + +A MK++ V+VN    P
Sbjct: 202 ISLHVPDVPANVHMINDKSIAKMKQDVVIVNVSRGP 237



 Score = 28.1 bits (61), Expect(2) = 0.027
 Identities = 22/87 (25%), Positives = 37/87 (42%), Gaps = 14/87 (16%)
 Frame = -2

Query: 579 GPVIDEVALVEHLKANPMFRVGLDVFEDE-----------PYMKPGLAEM---KNAVVVP 442
           GP++D  A++  L +  +F   +DV+E E            +    LA++    N +V P
Sbjct: 236 GPLVDTDAVIRGLDSGKVFGYAMDVYEGEVGVFNEDREGKEFPDARLADLIARPNVLVTP 295

Query: 441 HIASASKWTREGMATLAALNVLGKIKG 361
           H A  +      M   A  N L  ++G
Sbjct: 296 HTAFYTTHAVRNMVVKAFDNNLELVEG 322
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>PDXB_WIGBR (Q8D2P6) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)|
          Length = 378

 Score = 32.7 bits (73), Expect(2) = 0.058
 Identities = 21/52 (40%), Positives = 29/52 (55%)
 Frame = -2

Query: 579 GPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASAS 424
           G VID  +L+  LK     RV LDV+E+EP +   L  + + +  PHIA  S
Sbjct: 208 GSVIDNNSLLNILKEGKPIRVVLDVWENEPLICSKLLSLID-IGTPHIAGHS 258



 Score = 23.1 bits (48), Expect(2) = 0.058
 Identities = 9/21 (42%), Positives = 14/21 (66%)
 Frame = -1

Query: 652 TYHLINPERLAMMKKEAVLVN 590
           T+HLIN + L  +K   +L+N
Sbjct: 184 TWHLINKKILLDLKDNCILIN 204
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>LDHD_ECOLI (P52643) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH)|
           (Fermentative lactate dehydrogenase)
          Length = 329

 Score = 27.7 bits (60), Expect(2) = 0.097
 Identities = 13/31 (41%), Positives = 16/31 (51%)
 Frame = -1

Query: 682 ISLHPVLDKTTYHLINPERLAMMKKEAVLVN 590
           ISLH  L    YHL+N      MK   ++VN
Sbjct: 201 ISLHCPLTPENYHLLNEAAFEQMKNGVMIVN 231



 Score = 27.3 bits (59), Expect(2) = 0.097
 Identities = 12/29 (41%), Positives = 19/29 (65%)
 Frame = -2

Query: 579 GPVIDEVALVEHLKANPMFRVGLDVFEDE 493
           G +ID  A +E LK   +  +G+DV+E+E
Sbjct: 235 GALIDSQAAIEALKNQKIGSLGMDVYENE 263
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>PDXB_SALTY (P60802) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)|
          Length = 378

 Score = 35.8 bits (81), Expect = 0.12
 Identities = 24/60 (40%), Positives = 31/60 (51%)
 Frame = -2

Query: 579 GPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA 400
           GPV+D  AL+  L A     V LDV+E EP +   L E  + +   HIA    +T EG A
Sbjct: 209 GPVVDNAALLARLNAGQPLSVVLDVWEGEPDLNVALLEAVD-IGTSHIAG---YTLEGKA 264
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>PDXB_SALTI (P60801) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)|
          Length = 378

 Score = 35.8 bits (81), Expect = 0.12
 Identities = 24/60 (40%), Positives = 31/60 (51%)
 Frame = -2

Query: 579 GPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA 400
           GPV+D  AL+  L A     V LDV+E EP +   L E  + +   HIA    +T EG A
Sbjct: 209 GPVVDNAALLARLNAGQPLSVVLDVWEGEPDLNVALLEAVD-IGTSHIAG---YTLEGKA 264
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>VANH_ENTFC (Q05709) D-specific alpha-keto acid dehydrogenase (EC 1.1.1.-)|
           (Vancomycin resistance protein vanH)
          Length = 322

 Score = 28.1 bits (61), Expect(2) = 0.13
 Identities = 12/36 (33%), Positives = 23/36 (63%)
 Frame = -1

Query: 682 ISLHPVLDKTTYHLINPERLAMMKKEAVLVNAKPWP 575
           ++LH  L+  T+++I+ E++  MK+ A L+N    P
Sbjct: 198 VTLHVPLNTDTHYIISHEQIQRMKQGAFLINTGRGP 233



 Score = 26.6 bits (57), Expect(2) = 0.13
 Identities = 19/63 (30%), Positives = 26/63 (41%), Gaps = 14/63 (22%)
 Frame = -2

Query: 579 GPVIDEVALVEHLKANPMFRVGLDVFEDEP-------YMKP-------GLAEMKNAVVVP 442
           GP++D   LV+ L+   +    LDV E E          KP        L  M N ++ P
Sbjct: 232 GPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQFLLKLQRMPNVIITP 291

Query: 441 HIA 433
           H A
Sbjct: 292 HTA 294
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>DDH_ZYMMO (P30799) 2-hydroxyacid dehydrogenase homolog (EC 1.1.1.-)|
          Length = 331

 Score = 30.0 bits (66), Expect(2) = 0.21
 Identities = 16/31 (51%), Positives = 18/31 (58%)
 Frame = -1

Query: 682 ISLHPVLDKTTYHLINPERLAMMKKEAVLVN 590
           ISLH  L    +H+IN E LA  KK   LVN
Sbjct: 203 ISLHCPLTPENHHMINEETLARAKKGFYLVN 233



 Score = 23.9 bits (50), Expect(2) = 0.21
 Identities = 10/29 (34%), Positives = 18/29 (62%)
 Frame = -2

Query: 579 GPVIDEVALVEHLKANPMFRVGLDVFEDE 493
           G ++D  A+++ LKA  +     DV+E+E
Sbjct: 237 GGLVDTKAVIKSLKAKHLGGYAADVYEEE 265
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>DDH_HAEIN (P44501) 2-hydroxyacid dehydrogenase homolog (EC 1.1.1.-)|
          Length = 331

 Score = 27.3 bits (59), Expect(2) = 0.27
 Identities = 13/31 (41%), Positives = 17/31 (54%)
 Frame = -1

Query: 682 ISLHPVLDKTTYHLINPERLAMMKKEAVLVN 590
           I+LH       YHL+N E  A MK   ++VN
Sbjct: 201 ITLHCPATPENYHLLNCEAFAKMKDGVMIVN 231



 Score = 26.2 bits (56), Expect(2) = 0.27
 Identities = 11/29 (37%), Positives = 19/29 (65%)
 Frame = -2

Query: 579 GPVIDEVALVEHLKANPMFRVGLDVFEDE 493
           G +ID  A ++ LK   +  +G+DV+E+E
Sbjct: 235 GSLIDTQAAIDALKQRKIGALGMDVYENE 263
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>YGDH_SCHPO (O94574) Putative 2-hydroxyacid dehydrogenase C1773.17c (EC|
           1.-.-.-)
          Length = 340

 Score = 34.7 bits (78), Expect = 0.28
 Identities = 17/55 (30%), Positives = 28/55 (50%)
 Frame = -2

Query: 579 GPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWT 415
           G +I+E A ++ +K+  + R GLDVF +EP       E     + PH    + +T
Sbjct: 252 GAIINEDAFIKAIKSGKVARAGLDVFLNEPTPNKFWLECDKVTIQPHCGVYTNFT 306
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>PDXB_ECOL6 (Q8FFH2) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)|
          Length = 378

 Score = 32.0 bits (71), Expect(2) = 0.44
 Identities = 23/60 (38%), Positives = 30/60 (50%)
 Frame = -2

Query: 579 GPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA 400
           G V+D  AL+  L       V LDV+E EP +   L + K  +  PHIA    +T EG A
Sbjct: 209 GAVVDNTALLTCLNEGQKLSVVLDVWEGEPELNVELLK-KVDIGTPHIAG---YTLEGKA 264



 Score = 20.8 bits (42), Expect(2) = 0.44
 Identities = 8/22 (36%), Positives = 14/22 (63%)
 Frame = -1

Query: 652 TYHLINPERLAMMKKEAVLVNA 587
           T HL + + +  +K  A+L+NA
Sbjct: 185 TLHLADEKLIRSLKPGAILINA 206
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>VANH_ENTFA (Q47748) D-specific alpha-keto acid dehydrogenase (EC 1.1.1.-)|
           (Vancomycin B-type resistance protein vanHB)
          Length = 323

 Score = 26.6 bits (57), Expect(2) = 0.57
 Identities = 18/64 (28%), Positives = 27/64 (42%), Gaps = 15/64 (23%)
 Frame = -2

Query: 579 GPVIDEVALVEHLKANPMFRVGLDVFE---------------DEPYMKPGLAEMKNAVVV 445
           G ++D  +LVE L +  +    LDV E               D P++   L  M N ++ 
Sbjct: 233 GALVDTGSLVEALGSGKLGGAALDVLEGEDQFVYTDCSQKVLDHPFLSQ-LLRMPNVIIT 291

Query: 444 PHIA 433
           PH A
Sbjct: 292 PHTA 295



 Score = 25.8 bits (55), Expect(2) = 0.57
 Identities = 12/31 (38%), Positives = 18/31 (58%)
 Frame = -1

Query: 682 ISLHPVLDKTTYHLINPERLAMMKKEAVLVN 590
           ++LH  L   T HLI   ++  MK+ A L+N
Sbjct: 199 VTLHVPLCADTRHLIGQRQIGEMKQGAFLIN 229
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>PDXB_ERWCT (Q6D2N5) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)|
          Length = 378

 Score = 33.5 bits (75), Expect = 0.61
 Identities = 23/60 (38%), Positives = 31/60 (51%)
 Frame = -2

Query: 579 GPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA 400
           GPV+D  AL+E L+      V LDV+E EP +   L    + +   HIA    +T EG A
Sbjct: 209 GPVVDNAALLEALQQGKKLSVILDVWEPEPGLSTDLLARVD-IGTAHIAG---YTLEGKA 264
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>SERA_SCHPO (P87228) Putative D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95)|
           (3-PGDH)
          Length = 466

 Score = 27.3 bits (59), Expect(2) = 0.71
 Identities = 17/66 (25%), Positives = 28/66 (42%), Gaps = 13/66 (19%)
 Frame = -2

Query: 579 GPVIDEVALVEHLKANPMFRVGLDVFEDEP-------------YMKPGLAEMKNAVVVPH 439
           G V+D  ALV+  K+  +    +DV+  EP                  L   KN ++ PH
Sbjct: 285 GTVVDIPALVDASKSGKIAGAAIDVYPSEPAGNGKDKFVDSLNSWTSELTHCKNIILTPH 344

Query: 438 IASASK 421
           I  +++
Sbjct: 345 IGGSTE 350



 Score = 24.6 bits (52), Expect(2) = 0.71
 Identities = 11/32 (34%), Positives = 19/32 (59%)
 Frame = -1

Query: 682 ISLHPVLDKTTYHLINPERLAMMKKEAVLVNA 587
           +SLH      T ++I+ +  A MK+ + L+NA
Sbjct: 251 VSLHVPASPETKNMISSKEFAAMKEGSYLINA 282
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>PDXB_SHIFL (Q83QR1) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)|
          Length = 378

 Score = 31.2 bits (69), Expect(2) = 0.72
 Identities = 23/60 (38%), Positives = 29/60 (48%)
 Frame = -2

Query: 579 GPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA 400
           G V+D  AL+  L       V LDV+E EP +   L   K  +  PHIA    +T EG A
Sbjct: 209 GAVVDNTALLTCLNEGQKLSVVLDVWEGEPELNVELL-TKVDIGTPHIAG---YTLEGKA 264



 Score = 20.8 bits (42), Expect(2) = 0.72
 Identities = 8/22 (36%), Positives = 14/22 (63%)
 Frame = -1

Query: 652 TYHLINPERLAMMKKEAVLVNA 587
           T HL + + +  +K  A+L+NA
Sbjct: 185 TLHLADEKLIRSLKPGAILINA 206
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>PDXB_ECO57 (Q8XCR0) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)|
          Length = 378

 Score = 31.2 bits (69), Expect(2) = 0.72
 Identities = 23/60 (38%), Positives = 29/60 (48%)
 Frame = -2

Query: 579 GPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA 400
           G V+D  AL+  L       V LDV+E EP +   L   K  +  PHIA    +T EG A
Sbjct: 209 GAVVDNTALLTCLNEGQKLSVVLDVWEGEPELNVELL-TKVDIGTPHIAG---YTLEGKA 264



 Score = 20.8 bits (42), Expect(2) = 0.72
 Identities = 8/22 (36%), Positives = 14/22 (63%)
 Frame = -1

Query: 652 TYHLINPERLAMMKKEAVLVNA 587
           T HL + + +  +K  A+L+NA
Sbjct: 185 TLHLADEKLIRSLKPGAILINA 206
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>Y2355_CORGL (P0C1E8) Hypothetical protein Cgl2355/cg2587 (EC 1.-.-.-)|
          Length = 304

 Score = 32.7 bits (73), Expect = 1.0
 Identities = 22/68 (32%), Positives = 32/68 (47%), Gaps = 1/68 (1%)
 Frame = -2

Query: 579 GPVIDEVALVEHLKANPMFRVGLDVFEDEPYM-KPGLAEMKNAVVVPHIASASKWTREGM 403
           GP+I+   LV+ L    +    LDV + EP      L EM N V+ PH A+ ++  R   
Sbjct: 218 GPLINTDDLVDALNNGTIAGAALDVTDPEPLPDSHPLWEMDNVVITPHTANTNERIRALT 277

Query: 402 ATLAALNV 379
             L   N+
Sbjct: 278 GELTLRNI 285
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>PDXB_YERPS (Q668W7) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)|
          Length = 375

 Score = 32.0 bits (71), Expect = 1.8
 Identities = 24/61 (39%), Positives = 32/61 (52%), Gaps = 1/61 (1%)
 Frame = -2

Query: 579 GPVIDEVALVEHLKANPMFRVGLDVFEDEPYMK-PGLAEMKNAVVVPHIASASKWTREGM 403
           G V+D  AL+  L+      V LDV+E EP +  P LA +   +  PHIA    +T EG 
Sbjct: 209 GAVVDNAALLRALEKGKKLSVVLDVWEPEPDLSLPLLARVD--IGTPHIAG---YTLEGK 263

Query: 402 A 400
           A
Sbjct: 264 A 264
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>PDXB_YERPE (Q8D0U3) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)|
          Length = 375

 Score = 32.0 bits (71), Expect = 1.8
 Identities = 24/61 (39%), Positives = 32/61 (52%), Gaps = 1/61 (1%)
 Frame = -2

Query: 579 GPVIDEVALVEHLKANPMFRVGLDVFEDEPYMK-PGLAEMKNAVVVPHIASASKWTREGM 403
           G V+D  AL+  L+      V LDV+E EP +  P LA +   +  PHIA    +T EG 
Sbjct: 209 GAVVDNAALLRALEKGKKLSVVLDVWEPEPDLSLPLLARVD--IGTPHIAG---YTLEGK 263

Query: 402 A 400
           A
Sbjct: 264 A 264
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>LDHD_LEUMC (P51011) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific|
           D-2-hydroxyacid dehydrogenase)
          Length = 331

 Score = 25.4 bits (54), Expect(2) = 2.0
 Identities = 13/32 (40%), Positives = 19/32 (59%)
 Frame = -1

Query: 682 ISLHPVLDKTTYHLINPERLAMMKKEAVLVNA 587
           ISL+       +HLIN + +A MK   V++NA
Sbjct: 202 ISLYVPGVPENHHLINADAIAKMKDGVVIMNA 233



 Score = 25.0 bits (53), Expect(2) = 2.0
 Identities = 17/63 (26%), Positives = 31/63 (49%), Gaps = 14/63 (22%)
 Frame = -2

Query: 579 GPVIDEVALVEHLKANPMFRVGLDVFEDEP--YMKPGLAE------------MKNAVVVP 442
           G ++D  A+++ L +  +   G+DV+E+E    MK GL +             +N ++ P
Sbjct: 236 GNLMDIDAIIDGLNSGKISDFGMDVYENEVACSMKIGLVKNSPDAKIADLIARENVMITP 295

Query: 441 HIA 433
           H A
Sbjct: 296 HTA 298
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>NIP7_YEAST (Q08962) 60S ribosome subunit biogenesis protein NIP7|
          Length = 181

 Score = 31.2 bits (69), Expect = 3.1
 Identities = 20/63 (31%), Positives = 31/63 (49%), Gaps = 6/63 (9%)
 Frame = -2

Query: 489 YMKPGLAEMKNAVVVPHIASAS----KWTREGMATL--AALNVLGKIKGYPVWGNPNAVE 328
           Y+   +A++  +V  P++ S      K+T+ G   L   +L VL K   Y +W  PN   
Sbjct: 46  YVPDHVAKLATSVARPNLMSLGICLGKFTKTGKFRLHITSLTVLAKHAKYKIWIKPNGEM 105

Query: 327 PFL 319
           PFL
Sbjct: 106 PFL 108
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>YP113_YEAST (Q02961) Putative 2-hydroxyacid dehydrogenase YPL113C (EC 1.-.-.-)|
          Length = 396

 Score = 31.2 bits (69), Expect = 3.1
 Identities = 18/51 (35%), Positives = 28/51 (54%), Gaps = 1/51 (1%)
 Frame = -2

Query: 579 GPVIDEVALVEHLKANPMFRVGLDVFE-DEPYMKPGLAEMKNAVVVPHIAS 430
           G  IDE  L++ L++  +   GLDVF+ +E  +K  L    +   +PHI S
Sbjct: 314 GTCIDEDVLLDALESGKVASCGLDVFKNEETRVKQELLRRWDVTALPHIGS 364
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>PDXB_ECOLI (P05459) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)|
          Length = 378

 Score = 28.9 bits (63), Expect(2) = 3.3
 Identities = 22/60 (36%), Positives = 29/60 (48%)
 Frame = -2

Query: 579 GPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA 400
           G V+D  AL+  L       V LDV+E EP +   L + K  +   HIA    +T EG A
Sbjct: 209 GAVVDNTALLTCLNEGQKLSVVLDVWEGEPELNVELLK-KVDIGTSHIAG---YTLEGKA 264



 Score = 20.8 bits (42), Expect(2) = 3.3
 Identities = 8/22 (36%), Positives = 14/22 (63%)
 Frame = -1

Query: 652 TYHLINPERLAMMKKEAVLVNA 587
           T HL + + +  +K  A+L+NA
Sbjct: 185 TLHLADEKLIRSLKPGAILINA 206
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>LDHD_TREPA (O83080) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific|
           D-2-hydroxyacid dehydrogenase)
          Length = 331

 Score = 30.8 bits (68), Expect = 4.0
 Identities = 15/31 (48%), Positives = 19/31 (61%)
 Frame = -1

Query: 682 ISLHPVLDKTTYHLINPERLAMMKKEAVLVN 590
           ISLH    K ++HLIN + +A MK    LVN
Sbjct: 202 ISLHMPATKDSHHLINAKTIAQMKDGVYLVN 232
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>LDHD_STAAW (Q8NUT2) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific|
           D-2-hydroxyacid dehydrogenase)
          Length = 330

 Score = 30.8 bits (68), Expect = 4.0
 Identities = 15/32 (46%), Positives = 20/32 (62%)
 Frame = -1

Query: 682 ISLHPVLDKTTYHLINPERLAMMKKEAVLVNA 587
           ISLH   +K +YHL +      +KK A+LVNA
Sbjct: 202 ISLHVPANKESYHLFDKAMFDHVKKGAILVNA 233
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>LDHD_STAAU (P72357) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific|
           D-2-hydroxyacid dehydrogenase)
          Length = 330

 Score = 30.8 bits (68), Expect = 4.0
 Identities = 15/32 (46%), Positives = 20/32 (62%)
 Frame = -1

Query: 682 ISLHPVLDKTTYHLINPERLAMMKKEAVLVNA 587
           ISLH   +K +YHL +      +KK A+LVNA
Sbjct: 202 ISLHVPANKESYHLFDKAMFDHVKKGAILVNA 233
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>LDHD_STAAS (Q6G6F1) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific|
           D-2-hydroxyacid dehydrogenase)
          Length = 330

 Score = 30.8 bits (68), Expect = 4.0
 Identities = 15/32 (46%), Positives = 20/32 (62%)
 Frame = -1

Query: 682 ISLHPVLDKTTYHLINPERLAMMKKEAVLVNA 587
           ISLH   +K +YHL +      +KK A+LVNA
Sbjct: 202 ISLHVPANKESYHLFDKAMFDHVKKGAILVNA 233
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>LDHD_STAAR (Q6GDS2) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific|
           D-2-hydroxyacid dehydrogenase)
          Length = 330

 Score = 30.8 bits (68), Expect = 4.0
 Identities = 15/32 (46%), Positives = 20/32 (62%)
 Frame = -1

Query: 682 ISLHPVLDKTTYHLINPERLAMMKKEAVLVNA 587
           ISLH   +K +YHL +      +KK A+LVNA
Sbjct: 202 ISLHVPANKESYHLFDKTMFDHVKKGAILVNA 233
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>LDHD_STAAN (P99116) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific|
           D-2-hydroxyacid dehydrogenase)
          Length = 330

 Score = 30.8 bits (68), Expect = 4.0
 Identities = 15/32 (46%), Positives = 20/32 (62%)
 Frame = -1

Query: 682 ISLHPVLDKTTYHLINPERLAMMKKEAVLVNA 587
           ISLH   +K +YHL +      +KK A+LVNA
Sbjct: 202 ISLHVPANKESYHLFDKAMFDHVKKGAILVNA 233
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>LDHD_STAAM (P63940) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific|
           D-2-hydroxyacid dehydrogenase)
          Length = 330

 Score = 30.8 bits (68), Expect = 4.0
 Identities = 15/32 (46%), Positives = 20/32 (62%)
 Frame = -1

Query: 682 ISLHPVLDKTTYHLINPERLAMMKKEAVLVNA 587
           ISLH   +K +YHL +      +KK A+LVNA
Sbjct: 202 ISLHVPANKESYHLFDKAMFDHVKKGAILVNA 233
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>LDHD_STAAC (Q5HD29) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific|
           D-2-hydroxyacid dehydrogenase)
          Length = 330

 Score = 30.8 bits (68), Expect = 4.0
 Identities = 15/32 (46%), Positives = 20/32 (62%)
 Frame = -1

Query: 682 ISLHPVLDKTTYHLINPERLAMMKKEAVLVNA 587
           ISLH   +K +YHL +      +KK A+LVNA
Sbjct: 202 ISLHVPANKESYHLFDKAMFDHVKKGAILVNA 233
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>CSN12_ASHGO (Q75BU2) COP9 signalosome complex subunit 12|
          Length = 412

 Score = 30.4 bits (67), Expect = 5.2
 Identities = 17/39 (43%), Positives = 19/39 (48%)
 Frame = +2

Query: 494 SSSKTSRPTRNMGLALRCSTSATSSITGPRLRVHQHCLL 610
           S   +  P R +  AL  STSAT    G RL  H  CLL
Sbjct: 336 SGGSSQLPIRIIAAALAYSTSATPDAGGERLLDHTECLL 374
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>SERA_YEAST (P40054) D-3-phosphoglycerate dehydrogenase 1 (EC 1.1.1.95) (3-PGDH|
           1)
          Length = 469

 Score = 30.4 bits (67), Expect = 5.2
 Identities = 19/67 (28%), Positives = 32/67 (47%), Gaps = 14/67 (20%)
 Frame = -2

Query: 579 GPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPG--------------LAEMKNAVVVP 442
           G V+D  +L++ +KAN +    LDV+  EP  K G              L  + N ++ P
Sbjct: 288 GTVVDIPSLIQAVKANKIAGAALDVYPHEP-AKNGEGSFNDELNSWTSELVSLPNIILTP 346

Query: 441 HIASASK 421
           HI  +++
Sbjct: 347 HIGGSTE 353
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>SER33_YEAST (P40510) D-3-phosphoglycerate dehydrogenase 2 (EC 1.1.1.95) (3-PGDH|
           2)
          Length = 469

 Score = 30.4 bits (67), Expect = 5.2
 Identities = 19/67 (28%), Positives = 32/67 (47%), Gaps = 14/67 (20%)
 Frame = -2

Query: 579 GPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPG--------------LAEMKNAVVVP 442
           G V+D  +L++ +KAN +    LDV+  EP  K G              L  + N ++ P
Sbjct: 288 GTVVDIPSLIQAVKANKIAGAALDVYPHEP-AKNGEGSFNDELNSWTSELVSLPNIILTP 346

Query: 441 HIASASK 421
           HI  +++
Sbjct: 347 HIGGSTE 353
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>LDHD_STAES (Q8CN22) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific|
           D-2-hydroxyacid dehydrogenase)
          Length = 330

 Score = 30.0 bits (66), Expect = 6.8
 Identities = 15/32 (46%), Positives = 20/32 (62%)
 Frame = -1

Query: 682 ISLHPVLDKTTYHLINPERLAMMKKEAVLVNA 587
           ISLH   +K ++HL +      +KK AVLVNA
Sbjct: 202 ISLHVPANKDSFHLFDNNMFKNVKKGAVLVNA 233
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>LDHD_STAEQ (Q5HLA0) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific|
           D-2-hydroxyacid dehydrogenase)
          Length = 330

 Score = 30.0 bits (66), Expect = 6.8
 Identities = 15/32 (46%), Positives = 20/32 (62%)
 Frame = -1

Query: 682 ISLHPVLDKTTYHLINPERLAMMKKEAVLVNA 587
           ISLH   +K ++HL +      +KK AVLVNA
Sbjct: 202 ISLHVPANKDSFHLFDNNMFKNVKKGAVLVNA 233
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>PDXB_SHEVI (Q56733) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)|
           (Fragment)
          Length = 274

 Score = 29.6 bits (65), Expect = 8.9
 Identities = 19/52 (36%), Positives = 27/52 (51%)
 Frame = -2

Query: 579 GPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASAS 424
           G VID  AL++  +  P  ++ LDV+E EP     L  +   +  PHIA  S
Sbjct: 96  GEVIDNRALIKVKQQRPDIKLVLDVWEGEPNPMHELIPLVE-LATPHIAGYS 146
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>PDXB_SHEON (Q8ECR2) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)|
          Length = 376

 Score = 29.6 bits (65), Expect = 8.9
 Identities = 19/52 (36%), Positives = 25/52 (48%)
 Frame = -2

Query: 579 GPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASAS 424
           G VID  AL++  +     ++ LDV+E EP   P L         PHIA  S
Sbjct: 210 GDVIDNQALIKVKQQRDDLKLVLDVWEGEPNPMPELVPFAE-FATPHIAGYS 260


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 93,401,236
Number of Sequences: 219361
Number of extensions: 1867110
Number of successful extensions: 5809
Number of sequences better than 10.0: 93
Number of HSP's better than 10.0 without gapping: 5526
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5799
length of database: 80,573,946
effective HSP length: 108
effective length of database: 56,882,958
effective search space used: 6712189044
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
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