>CO4A2_ASCSU (P27393) Collagen alpha-2(IV) chain precursor|
          Length = 1763

 Score = 35.0 bits (79), Expect = 0.13
 Identities = 32/90 (35%), Positives = 41/90 (45%), Gaps = 3/90 (3%)
 Frame = +1

Query: 205 AGPRRRRGIPS-RAVDGGEPPQGGHLELEDADVLGGLPEQHVDIGVPGVRDYLLELPQPP 381
           AGP   +G P  R VDG   P  G    +    L GLP +  ++G+PGVR      P   
Sbjct: 441 AGPPGAKGEPGPRGVDGQSIP--GLPGKDGRPGLDGLPGRKGEMGLPGVRG-----PPGD 493

Query: 382 QHHVLEGPPVHQRCHHPLGLSHREG--GLP 465
             + L GPP  +    P G   R+G  GLP
Sbjct: 494 SLNGLPGPPGPRGPQGPKGYDGRDGAPGLP 523



 Score = 28.9 bits (63), Expect = 9.3
 Identities = 30/88 (34%), Positives = 35/88 (39%), Gaps = 4/88 (4%)
 Frame = +1

Query: 205 AGPRRRRGIPSRAVDGGEPPQGGHLELEDADVLGGLPEQHVDIGVPGVRDYLLELPQPP- 381
           AGPR + G P      G P   G   L+    + GLP Q  + G PG RD       PP 
Sbjct: 302 AGPRGKEGRPGLP---GPPGFKGDRGLDGLPGVPGLPGQKGEAGFPG-RDGAKGARGPPG 357

Query: 382 ---QHHVLEGPPVHQRCHHPLGLSHREG 456
                   +GPP       P GL  REG
Sbjct: 358 PPGGGEFSDGPP------GPPGLPGREG 379

>PYGO_DROME (Q9V9W8) Protein pygopus (Protein gammy legs)|
          Length = 815

 Score = 33.9 bits (76), Expect = 0.29
 Identities = 32/124 (25%), Positives = 47/124 (37%), Gaps = 10/124 (8%)
 Frame = +1

Query: 133 PPTQLMHNCIHS-----GAQNL*PWALRWAGPRRRRGIPSRAVDGGEPPQGGHL-----E 282
           PP    H+ ++S     G  N  P  L+   P    G  +   +    P  G +      
Sbjct: 482 PPAMSPHHSLNSAGPSPGMPNSGPSPLQ--SPAGPNGPNNNNSNNNNGPMMGQMIPNAVP 539

Query: 283 LEDADVLGGLPEQHVDIGVPGVRDYLLELPQPPQHHVLEGPPVHQRCHHPLGLSHREGGL 462
           ++    +GG P  H    +PG+    +  PQ P H    GPP     +HP    H  GG 
Sbjct: 540 MQHQQHMGGGPPGHGPGPMPGMGMNQMLPPQQPSHL---GPPHPNMMNHPHHPHHHPGGP 596

Query: 463 PSHL 474
           P H+
Sbjct: 597 PPHM 600

>HEMH_RHOBA (Q7UFZ7) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme|
           synthetase)
          Length = 351

 Score = 32.7 bits (73), Expect = 0.65
 Identities = 12/18 (66%), Positives = 13/18 (72%)
 Frame = -2

Query: 234 WDAAPPSRSGPPQRPWLE 181
           WD    SRSGPP +PWLE
Sbjct: 216 WDLVYQSRSGPPSQPWLE 233

>CO5A2_HUMAN (P05997) Collagen alpha-2(V) chain precursor|
          Length = 1496

 Score = 32.3 bits (72), Expect = 0.85
 Identities = 19/53 (35%), Positives = 25/53 (47%)
 Frame = +1

Query: 193 ALRWAGPRRRRGIPSRAVDGGEPPQGGHLELEDADVLGGLPEQHVDIGVPGVR 351
           A+ +AGP+   G P    + GEP Q G         L G P  H   GVPG++
Sbjct: 841 AVGFAGPQGSDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLK 893

>HEMH_LEIXX (Q6AHF2) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme|
           synthetase)
          Length = 389

 Score = 32.0 bits (71), Expect = 1.1
 Identities = 12/18 (66%), Positives = 12/18 (66%)
 Frame = -2

Query: 234 WDAAPPSRSGPPQRPWLE 181
           WD    SRSGPP  PWLE
Sbjct: 255 WDLVYQSRSGPPSMPWLE 272

>RNPA_NOCFA (Q5YMR7) Ribonuclease P protein component (EC 3.1.26.5) (RNaseP|
           protein) (RNase P protein) (Protein C5)
          Length = 156

 Score = 30.8 bits (68), Expect = 2.5
 Identities = 24/84 (28%), Positives = 37/84 (44%), Gaps = 5/84 (5%)
 Frame = -2

Query: 429 VVASLMHRRPFQHMVLRRLRELKKIVPDARDADVDVLLR-----QTAEYICILELKVAAL 265
           +V+  +     +H V RRLR +   + D   AD DV++R      TA+   +     + L
Sbjct: 68  IVSKAVGSAVVRHRVARRLRHMCATLVDEVPADADVVIRALPGAATADSAELARQVRSGL 127

Query: 264 RRLSAIYGA*WDAAPPSRSGPPQR 193
           R+L    G     AP + SG   R
Sbjct: 128 RKLGVTPGGGRSPAPRAHSGARPR 151

>PIF3_ARATH (O80536) Phytochrome-interacting factor 3 (Phytochrome-associated|
           protein 3) (Basic helix-loop-helix protein 8) (bHLH8)
           (AtbHLH008)
          Length = 524

 Score = 30.8 bits (68), Expect = 2.5
 Identities = 27/108 (25%), Positives = 46/108 (42%), Gaps = 2/108 (1%)
 Frame = -2

Query: 516 HSNLGRERGRDTQREMRRKATFTVGKAK--GVVASLMHRRPFQHMVLRRLRELKKIVPDA 343
           HS    E   D ++E     T    K      V +L  RR  +  +  ++R L++++P+ 
Sbjct: 315 HSEDVEEESGDGRKEAGPSRTGLGSKRSRSAEVHNLSERRR-RDRINEKMRALQELIPNC 373

Query: 342 RDADVDVLLRQTAEYICILELKVAALRRLSAIYGA*WDAAPPSRSGPP 199
              D   +L +  EY+  L+L+V  +   S  Y       PP+   PP
Sbjct: 374 NKVDKASMLDEAIEYLKSLQLQVQIMSMASGYY------LPPAVMFPP 415

>Y381_TREPA (O83396) Hypothetical protein TP0381|
          Length = 238

 Score = 30.8 bits (68), Expect = 2.5
 Identities = 16/29 (55%), Positives = 18/29 (62%)
 Frame = +2

Query: 434 LAFPTVKVAFLLISLCVSLPLSLPRLLCH 520
           L F    VA LL +L V LP +LPRLL H
Sbjct: 18  LHFAIASVAVLLSALFVLLPFALPRLLAH 46

>HEMH_MYCTU (P0A576) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme|
           synthetase)
          Length = 344

 Score = 30.4 bits (67), Expect = 3.2
 Identities = 13/18 (72%), Positives = 14/18 (77%)
 Frame = -2

Query: 234 WDAAPPSRSGPPQRPWLE 181
           +D A  SRSGPPQ PWLE
Sbjct: 207 FDLAWQSRSGPPQVPWLE 224

>HEMH_MYCBO (P0A577) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme|
           synthetase)
          Length = 344

 Score = 30.4 bits (67), Expect = 3.2
 Identities = 13/18 (72%), Positives = 14/18 (77%)
 Frame = -2

Query: 234 WDAAPPSRSGPPQRPWLE 181
           +D A  SRSGPPQ PWLE
Sbjct: 207 FDLAWQSRSGPPQVPWLE 224

>DPY2_CAEEL (P35799) Cuticle collagen dpy-2 precursor (Protein dumpy-2)|
          Length = 360

 Score = 30.4 bits (67), Expect = 3.2
 Identities = 22/67 (32%), Positives = 28/67 (41%)
 Frame = +1

Query: 208 GPRRRRGIPSRAVDGGEPPQGGHLELEDADVLGGLPEQHVDIGVPGVRDYLLELPQPPQH 387
           GPR   G P    D GE   GG    +      G P     IG PG    + +  + P+ 
Sbjct: 174 GPRGVPGHPGFPGDPGEYGIGGRPGSDGMPGKPGDPGLAGPIGPPGESGPIGDKGRTPEA 233

Query: 388 HVLEGPP 408
           HV+ GPP
Sbjct: 234 HVIPGPP 240

>MEIS2_MOUSE (P97367) Homeobox protein Meis2 (Meis1-related protein 1)|
          Length = 477

 Score = 30.0 bits (66), Expect = 4.2
 Identities = 13/43 (30%), Positives = 22/43 (51%)
 Frame = +1

Query: 370 PQPPQHHVLEGPPVHQRCHHPLGLSHREGGLPSHLSLCISPSL 498
           P PP HH+  GPP+H   H+     H    +P+ +   ++ +L
Sbjct: 32  PIPPVHHLNHGPPLHATQHYGAHAPH-PNVMPASMGSAVNDAL 73

>MEIS2_HUMAN (O14770) Homeobox protein Meis2 (Meis1-related protein 1)|
          Length = 477

 Score = 30.0 bits (66), Expect = 4.2
 Identities = 13/43 (30%), Positives = 22/43 (51%)
 Frame = +1

Query: 370 PQPPQHHVLEGPPVHQRCHHPLGLSHREGGLPSHLSLCISPSL 498
           P PP HH+  GPP+H   H+     H    +P+ +   ++ +L
Sbjct: 32  PIPPVHHLNHGPPLHATQHYGAHAPH-PNVMPASMGSAVNDAL 73

>DNAA_STRCH (Q9ZH75) Chromosomal replication initiator protein dnaA|
          Length = 624

 Score = 30.0 bits (66), Expect = 4.2
 Identities = 25/76 (32%), Positives = 28/76 (36%), Gaps = 2/76 (2%)
 Frame = +1

Query: 196 LRWAGPRRRRGIPSRAVDGGEP--PQGGHLELEDADVLGGLPEQHVDIGVPGVRDYLLEL 369
           L W  PR   G   R    GEP      + E E+       PEQ         + Y    
Sbjct: 167 LSWQQPRHG-GYQDREQPSGEPYRESESYRERENEQYREQAPEQWR-------QPYGTGR 218

Query: 370 PQPPQHHVLEGPPVHQ 417
           PQ PQH    GPP HQ
Sbjct: 219 PQQPQHDYRSGPPEHQ 234

>HEMH_PROFR (P72183) Ferrochelatase (EC 4.99.1.1) (Protoheme ferro-lyase) (Heme|
           synthetase)
          Length = 352

 Score = 30.0 bits (66), Expect = 4.2
 Identities = 16/41 (39%), Positives = 24/41 (58%), Gaps = 3/41 (7%)
 Frame = -2

Query: 234 WDAAPPSRSGPPQRPWLEVLSPRVDAIVH*L---GRRNISC 121
           W+ A  SRSG P+ PWLE   P ++ ++  L   G R++ C
Sbjct: 219 WELAYQSRSGSPRTPWLE---PDINDVITRLAGEGVRDVIC 256

>ATX2L_MOUSE (Q7TQH0) Ataxin-2-like protein|
          Length = 1049

 Score = 29.6 bits (65), Expect = 5.5
 Identities = 19/49 (38%), Positives = 22/49 (44%), Gaps = 4/49 (8%)
 Frame = +1

Query: 370 PQPPQH--HVLEGPPVHQRC--HHPLGLSHREGGLPSHLSLCISPSLPP 504
           PQPPQ      + PP  Q      P G S   GGLP  L+   +P  PP
Sbjct: 4   PQPPQQTSQPQQPPPTQQAVARRSPGGTSPPNGGLPGPLTATAAPPGPP 52

>CO1A2_CHICK (P02467) Collagen alpha-2(I) chain precursor (Fragments)|
          Length = 1362

 Score = 29.3 bits (64), Expect = 7.2
 Identities = 21/59 (35%), Positives = 25/59 (42%)
 Frame = +1

Query: 205 AGPRRRRGIPSRAVDGGEPPQGGHLELEDADVLGGLPEQHVDIGVPGVRDYLLELPQPP 381
           AGPR   G+P  +   G P   G   L  A    GLP      G+PG R     +P PP
Sbjct: 277 AGPRGEIGLPGSSGPVGPPGNPGANGLPGAKGAAGLPGVAGAPGLPGPRG----IPGPP 331

>LZTS2_HUMAN (Q9BRK4) Leucine zipper putative tumor suppressor 2 (Protein|
           LAPSER1)
          Length = 669

 Score = 29.3 bits (64), Expect = 7.2
 Identities = 20/52 (38%), Positives = 26/52 (50%)
 Frame = +1

Query: 370 PQPPQHHVLEGPPVHQRCHHPLGLSHREGGLPSHLSLCISPSLPPQVAVSLT 525
           P PP+HH   GPP         GL    GG  +   LC  P++PP+ AV +T
Sbjct: 42  PAPPRHH---GPPGPTFFRQQDGL--LRGGYEAQEPLC--PAVPPRKAVPVT 86

>PTN1_HUMAN (P18031) Tyrosine-protein phosphatase non-receptor type 1 (EC|
           3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B)
          Length = 435

 Score = 29.3 bits (64), Expect = 7.2
 Identities = 9/12 (75%), Positives = 10/12 (83%)
 Frame = -3

Query: 50  CGHTWEFVWQQK 15
           CGH WE VW+QK
Sbjct: 92  CGHFWEMVWEQK 103

>PTN1_CHICK (O13016) Tyrosine-protein phosphatase non-receptor type 1 (EC|
           3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B)
           (CPTP1)
          Length = 434

 Score = 29.3 bits (64), Expect = 7.2
 Identities = 9/12 (75%), Positives = 10/12 (83%)
 Frame = -3

Query: 50  CGHTWEFVWQQK 15
           CGH WE VW+QK
Sbjct: 92  CGHFWEMVWEQK 103

>PTN1_RAT (P20417) Tyrosine-protein phosphatase non-receptor type 1 (EC|
           3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B)
          Length = 432

 Score = 29.3 bits (64), Expect = 7.2
 Identities = 9/12 (75%), Positives = 10/12 (83%)
 Frame = -3

Query: 50  CGHTWEFVWQQK 15
           CGH WE VW+QK
Sbjct: 92  CGHFWEMVWEQK 103

>PTN1_MOUSE (P35821) Tyrosine-protein phosphatase non-receptor type 1 (EC|
           3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B)
           (Protein-protein-tyrosine phosphatase HA2) (PTP-HA2)
          Length = 432

 Score = 29.3 bits (64), Expect = 7.2
 Identities = 9/12 (75%), Positives = 10/12 (83%)
 Frame = -3

Query: 50  CGHTWEFVWQQK 15
           CGH WE VW+QK
Sbjct: 92  CGHFWEMVWEQK 103

>MLL2_HUMAN (O14686) Myeloid/lymphoid or mixed-lineage leukemia protein 2|
            (ALL1-related protein)
          Length = 5262

 Score = 28.9 bits (63), Expect = 9.3
 Identities = 23/68 (33%), Positives = 29/68 (42%)
 Frame = +1

Query: 295  DVLGGLPEQHVDIGVPGVRDYLLELPQPPQHHVLEGPPVHQRCHHPLGLSHREGGLPSHL 474
            DVLG   EQH+  G PG+      L +P     L+G         PLG       + S+ 
Sbjct: 1622 DVLGSEREQHLGCGTPGLEGSRTPLQRP----FLQG-------GLPLGNLPSSSPMDSYP 1670

Query: 475  SLCISPSL 498
             LC SP L
Sbjct: 1671 GLCQSPFL 1678

>PP1RA_PIG (Q767K9) Serine/threonine-protein phosphatase 1 regulatory subunit 10|
            (MHC class I region proline-rich protein CAT53) (Protein
            FB19)
          Length = 925

 Score = 28.9 bits (63), Expect = 9.3
 Identities = 25/84 (29%), Positives = 29/84 (34%)
 Frame = +1

Query: 232  PSRAVDGGEPPQGGHLELEDADVLGGLPEQHVDIGVPGVRDYLLELPQPPQHHVLEGPPV 411
            P     GG    GGH   E      G P  H    VPG R +    P P +H   +GP  
Sbjct: 816  PHEGPGGGMGAGGGHRPHEGPG--HGGPHGHRPHDVPGHRGHDHRGPPPHEHRGHDGPGH 873

Query: 412  HQRCHHPLGLSHREGGLPSHLSLC 483
                H      H  GG  S   +C
Sbjct: 874  GGGGHRGHDGGHNHGGDMSKRPVC 897

>GUAA_AQUAE (O66601) GMP synthase [glutamine-hydrolyzing] (EC 6.3.5.2)|
           (Glutamine amidotransferase) (GMP synthetase)
          Length = 510

 Score = 28.9 bits (63), Expect = 9.3
 Identities = 21/71 (29%), Positives = 34/71 (47%)
 Frame = -2

Query: 477 REMRRKATFTVGKAKGVVASLMHRRPFQHMVLRRLRELKKIVPDARDADVDVLLRQTAEY 298
           RE+ +     +GK  GV   ++ R PF    L       +I+ +    D+++L  + A+Y
Sbjct: 362 RELFKDEVRKIGKLLGVPEEILRRHPFPGPGL-----AIRIIGEVNKKDLEIL--RKADY 414

Query: 297 ICILELKVAAL 265
           I I ELK   L
Sbjct: 415 IFIQELKKEGL 425

>SETD7_MOUSE (Q8VHL1) Histone-lysine N-methyltransferase, H3 lysine-4 specific|
           SET7 (EC 2.1.1.43) (Histone H3-K4 methyltransferase)
           (H3-K4-HMTase) (SET domain-containing protein 7)
          Length = 366

 Score = 28.9 bits (63), Expect = 9.3
 Identities = 16/40 (40%), Positives = 22/40 (55%), Gaps = 1/40 (2%)
 Frame = -2

Query: 294 CILELK-VAALRRLSAIYGA*WDAAPPSRSGPPQRPWLEV 178
           CI  L+ V A   L+  YG  +D +PP +SGP    W +V
Sbjct: 318 CIRTLRAVEAEEELTVAYG--YDHSPPGKSGPEAPEWYQV 355

>CO4A2_CAEEL (P17140) Collagen alpha-2(IV) chain precursor (Lethal protein 2)|
          Length = 1758

 Score = 28.9 bits (63), Expect = 9.3
 Identities = 18/47 (38%), Positives = 22/47 (46%)
 Frame = +1

Query: 205 AGPRRRRGIPSRAVDGGEPPQGGHLELEDADVLGGLPEQHVDIGVPG 345
           AGPR + G P  A   G P   G   L+    + GLP Q  + G PG
Sbjct: 300 AGPRGKEGRPGNA---GPPGFKGDRGLDGLGGIPGLPGQKGEAGYPG 343

>CO8A2_HUMAN (P25067) Collagen alpha-2(VIII) chain precursor (Endothelial|
           collagen)
          Length = 703

 Score = 28.9 bits (63), Expect = 9.3
 Identities = 17/48 (35%), Positives = 21/48 (43%)
 Frame = +1

Query: 208 GPRRRRGIPSRAVDGGEPPQGGHLELEDADVLGGLPEQHVDIGVPGVR 351
           G R   G+P    D GEP + G    +    LGG P      G+PG R
Sbjct: 325 GDRGPAGVPGLLGDRGEPGEDGEPGEQGPQGLGGPPGLPGSAGLPGRR 372

>NRTN_MOUSE (P97463) Neurturin precursor|
          Length = 195

 Score = 28.9 bits (63), Expect = 9.3
 Identities = 15/32 (46%), Positives = 16/32 (50%)
 Frame = +1

Query: 175 QNL*PWALRWAGPRRRRGIPSRAVDGGEPPQG 270
           + L PWA R  GPRRR G   R    G  P G
Sbjct: 71  RELSPWAARIPGPRRRAGPRRRRARPGARPCG 102


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 74,146,520
Number of Sequences: 219361
Number of extensions: 1589688
Number of successful extensions: 5394
Number of sequences better than 10.0: 29
Number of HSP's better than 10.0 without gapping: 5038
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5385
length of database: 80,573,946
effective HSP length: 105
effective length of database: 57,541,041
effective search space used: 4142954952
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)