ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | rbaak4l17 |
|---|---|
| Clone Library Name | barley_pub |
>NLE1_BOVIN (Q58D20) Notchless homolog 1| Length = 485 Score = 220 bits (560), Expect = 2e-57 Identities = 98/138 (71%), Positives = 119/138 (86%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SGSDDFT+FLW P K+P ARMTGHQ ++N V FSPD + +ASASFDKS+KLW+G TGK Sbjct: 346 SGSDDFTLFLWSPAEDKKPLARMTGHQALINQVVFSPDSRVIASASFDKSIKLWDGRTGK 405 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 ++ + RGHVA VYQI+WSADSRLL+SGS DSTLKVWD++A+KL DLPGHADEVYAVDWS Sbjct: 406 YLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLSTDLPGHADEVYAVDWS 465 Query: 175 PDGEKVVSGGKDRALKLW 122 PDG++V SGGKD+ L++W Sbjct: 466 PDGQRVASGGKDKCLRIW 483 Score = 83.6 bits (205), Expect = 3e-16 Identities = 50/144 (34%), Positives = 78/144 (54%), Gaps = 6/144 (4%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SGS D T+ W+ + ++ P GH+ V + +SPDG+ LAS + + LW+ TGK Sbjct: 131 SGSGDTTVRFWDLS-TETPHFTCQGHRHWVLSISWSPDGKKLASGCKNGQILLWDPSTGK 189 Query: 355 FV-TAFRGHVADVYQISW-----SADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEV 194 V A GH + +SW + + R + S SKD +++VWD A + ++ L GHA V Sbjct: 190 QVGRALTGHSKWITALSWEPLHANPECRYVASSSKDGSVRVWDTTAGRCERTLTGHAQSV 249 Query: 193 YAVDWSPDGEKVVSGGKDRALKLW 122 + W DG + S +DR +K+W Sbjct: 250 TCLRWGGDG-LLYSASQDRTIKVW 272 Score = 72.4 bits (176), Expect = 7e-13 Identities = 41/122 (33%), Positives = 66/122 (54%), Gaps = 6/122 (4%) Frame = -2 Query: 469 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 290 + GH + V V FSP G++LAS S D +V+ W+ T +GH V ISWS D + Sbjct: 110 LEGHSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHFTCQGHRHWVLSISWSPDGK 169 Query: 289 LLLSGSKDSTLKVWD-IRARKLKQDLPGHADEVYAVDW-----SPDGEKVVSGGKDRALK 128 L SG K+ + +WD +++ + L GH+ + A+ W +P+ V S KD +++ Sbjct: 170 KLASGCKNGQILLWDPSTGKQVGRALTGHSKWITALSWEPLHANPECRYVASSSKDGSVR 229 Query: 127 LW 122 +W Sbjct: 230 VW 231 Score = 58.5 bits (140), Expect = 1e-08 Identities = 26/76 (34%), Positives = 42/76 (55%) Frame = -2 Query: 349 TAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPD 170 ++ GH V +++S + L SGS D+T++ WD+ GH V ++ WSPD Sbjct: 108 SSLEGHSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHFTCQGHRHWVLSISWSPD 167 Query: 169 GEKVVSGGKDRALKLW 122 G+K+ SG K+ + LW Sbjct: 168 GKKLASGCKNGQILLW 183 Score = 50.1 bits (118), Expect = 4e-06 Identities = 45/181 (24%), Positives = 72/181 (39%), Gaps = 43/181 (23%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 S S D ++ +W+ T + + +TGH + V + + DG L SAS D+++K+W G Sbjct: 221 SSSKDGSVRVWDTTAGRCERT-LTGHAQSVTCLRWGGDGL-LYSASQDRTIKVWRAHDGV 278 Query: 355 FVTAFRGHVADVYQISWSADSRL------------------------------------- 287 +GH V ++ S D L Sbjct: 279 LCRTLQGHGHWVNTMALSTDYALRTGAFEPAEASVNAQDLRGSLQELKERALSRYNLVRG 338 Query: 286 -----LLSGSKDSTLKVWD-IRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKL 125 L+SGS D TL +W +K + GH + V +SPD + S D+++KL Sbjct: 339 QGPERLVSGSDDFTLFLWSPAEDKKPLARMTGHQALINQVVFSPDSRVIASASFDKSIKL 398 Query: 124 W 122 W Sbjct: 399 W 399
>NLE1_MOUSE (Q8VEJ4) Notchless homolog 1| Length = 484 Score = 219 bits (558), Expect = 4e-57 Identities = 98/138 (71%), Positives = 119/138 (86%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SGSDDFT+FLW P K+P ARMTGHQ ++N V FSPD + +ASASFDKS+KLW+G TGK Sbjct: 345 SGSDDFTLFLWSPAEDKKPLARMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRTGK 404 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 ++ + RGHVA VYQI+WSADSRLL+SGS DSTLKVWD++A+KL DLPGHADEVYAVDWS Sbjct: 405 YLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLATDLPGHADEVYAVDWS 464 Query: 175 PDGEKVVSGGKDRALKLW 122 PDG++V SGGKD+ L++W Sbjct: 465 PDGQRVASGGKDKCLRIW 482 Score = 76.6 bits (187), Expect = 4e-14 Identities = 47/144 (32%), Positives = 75/144 (52%), Gaps = 6/144 (4%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SGS D T+ W+ + ++ P GH+ V + +SPDG+ LAS + + LW+ TG Sbjct: 130 SGSGDTTVRFWDLS-TETPHFTCKGHRHWVLSISWSPDGKKLASGCKNGQILLWDPSTGL 188 Query: 355 FV-TAFRGHVADVYQISW-----SADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEV 194 V GH + +SW + + R + S SKD +++VWD A + ++ L GH V Sbjct: 189 QVGRTLTGHSKWITGLSWEPLHMNPECRYVASSSKDGSVRVWDTTAGRCERILTGHTQSV 248 Query: 193 YAVDWSPDGEKVVSGGKDRALKLW 122 + W DG + S +DR +K+W Sbjct: 249 TCLRWGGDG-LLYSASQDRTIKVW 271 Score = 70.1 bits (170), Expect = 4e-12 Identities = 40/122 (32%), Positives = 64/122 (52%), Gaps = 6/122 (4%) Frame = -2 Query: 469 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 290 + GH + V V FSP G++LAS S D +V+ W+ T +GH V ISWS D + Sbjct: 109 LEGHSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISWSPDGK 168 Query: 289 LLLSGSKDSTLKVWD-IRARKLKQDLPGHADEVYAVDW-----SPDGEKVVSGGKDRALK 128 L SG K+ + +WD ++ + L GH+ + + W +P+ V S KD +++ Sbjct: 169 KLASGCKNGQILLWDPSTGLQVGRTLTGHSKWITGLSWEPLHMNPECRYVASSSKDGSVR 228 Query: 127 LW 122 +W Sbjct: 229 VW 230 Score = 67.4 bits (163), Expect = 2e-11 Identities = 40/127 (31%), Positives = 63/127 (49%), Gaps = 5/127 (3%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHV-----YFSPDGQWLASASFDKSVKLWN 371 SG + + LW+P+ Q +TGH K + + + +P+ +++AS+S D SV++W+ Sbjct: 172 SGCKNGQILLWDPSTGLQVGRTLTGHSKWITGLSWEPLHMNPECRYVASSSKDGSVRVWD 231 Query: 370 GITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVY 191 G+ GH V + W D LL S S+D T+KVW L + L GH V Sbjct: 232 TTAGRCERILTGHTQSVTCLRWGGDG-LLYSASQDRTIKVWRAHDGVLCRTLQGHGHWVN 290 Query: 190 AVDWSPD 170 + S D Sbjct: 291 TMALSTD 297 Score = 58.5 bits (140), Expect = 1e-08 Identities = 26/76 (34%), Positives = 42/76 (55%) Frame = -2 Query: 349 TAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPD 170 ++ GH V +++S + L SGS D+T++ WD+ GH V ++ WSPD Sbjct: 107 SSLEGHSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISWSPD 166 Query: 169 GEKVVSGGKDRALKLW 122 G+K+ SG K+ + LW Sbjct: 167 GKKLASGCKNGQILLW 182 Score = 49.3 bits (116), Expect = 7e-06 Identities = 46/181 (25%), Positives = 72/181 (39%), Gaps = 43/181 (23%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 S S D ++ +W+ T + + +TGH + V + + DG L SAS D+++K+W G Sbjct: 220 SSSKDGSVRVWDTTAGRCERI-LTGHTQSVTCLRWGGDGL-LYSASQDRTIKVWRAHDGV 277 Query: 355 FVTAFRGHVADVYQISWSADSRL------------------------------------- 287 +GH V ++ S D L Sbjct: 278 LCRTLQGHGHWVNTMALSTDYALRTGAFEPAEATVNAQDLQGSLKELKERASSRYNLVRG 337 Query: 286 -----LLSGSKDSTLKVWD-IRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKL 125 L+SGS D TL +W +K + GH + V +SPD V S D+++KL Sbjct: 338 QGPERLVSGSDDFTLFLWSPAEDKKPLARMTGHQALINQVLFSPDSRIVASASFDKSIKL 397 Query: 124 W 122 W Sbjct: 398 W 398
>NLE1_PONPY (Q5RFF8) Notchless homolog 1| Length = 484 Score = 218 bits (555), Expect = 8e-57 Identities = 97/138 (70%), Positives = 118/138 (85%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SGSDDFT+FLW P K+P RMTGHQ ++N V FSPD + +ASASFDKS+KLW+G TGK Sbjct: 345 SGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRTGK 404 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 ++ + RGHVA VYQI+WSADSRLL+SGS DSTLKVWD++A+KL DLPGHADEVYAVDWS Sbjct: 405 YLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWS 464 Query: 175 PDGEKVVSGGKDRALKLW 122 PDG++V SGGKD+ L++W Sbjct: 465 PDGQRVASGGKDKCLRIW 482 Score = 79.0 bits (193), Expect = 8e-15 Identities = 47/144 (32%), Positives = 76/144 (52%), Gaps = 6/144 (4%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SGS D T+ W+ + ++ P GH+ V + +SPDG+ LAS + + LW+ TGK Sbjct: 130 SGSGDTTVRFWDLS-TETPHFTCKGHRHWVLSISWSPDGKKLASGCKNGQILLWDPSTGK 188 Query: 355 FV-TAFRGHVADVYQISW-----SADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEV 194 V GH + +SW + + R + S SKD ++++WD A + ++ L GH V Sbjct: 189 QVGRTLAGHSKWITGLSWEPLHANPECRYVASSSKDGSVRIWDTTAGRCERILTGHTQSV 248 Query: 193 YAVDWSPDGEKVVSGGKDRALKLW 122 + W DG + S +DR +K+W Sbjct: 249 TCLRWGGDG-LLYSASQDRTIKVW 271 Score = 72.0 bits (175), Expect = 1e-12 Identities = 40/122 (32%), Positives = 65/122 (53%), Gaps = 6/122 (4%) Frame = -2 Query: 469 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 290 + GH + V V FSP G++LAS S D +V+ W+ T +GH V ISWS D + Sbjct: 109 LEGHSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISWSPDGK 168 Query: 289 LLLSGSKDSTLKVWD-IRARKLKQDLPGHADEVYAVDW-----SPDGEKVVSGGKDRALK 128 L SG K+ + +WD +++ + L GH+ + + W +P+ V S KD +++ Sbjct: 169 KLASGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHANPECRYVASSSKDGSVR 228 Query: 127 LW 122 +W Sbjct: 229 IW 230 Score = 67.8 bits (164), Expect = 2e-11 Identities = 40/127 (31%), Positives = 63/127 (49%), Gaps = 5/127 (3%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHV-----YFSPDGQWLASASFDKSVKLWN 371 SG + + LW+P+ KQ + GH K + + + +P+ +++AS+S D SV++W+ Sbjct: 172 SGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHANPECRYVASSSKDGSVRIWD 231 Query: 370 GITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVY 191 G+ GH V + W D LL S S+D T+KVW L + L GH V Sbjct: 232 TTAGRCERILTGHTQSVTCLRWGGDG-LLYSASQDRTIKVWRAHDGVLCRTLQGHGHWVN 290 Query: 190 AVDWSPD 170 + S D Sbjct: 291 TMALSTD 297 Score = 58.5 bits (140), Expect = 1e-08 Identities = 26/76 (34%), Positives = 42/76 (55%) Frame = -2 Query: 349 TAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPD 170 ++ GH V +++S + L SGS D+T++ WD+ GH V ++ WSPD Sbjct: 107 SSLEGHSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISWSPD 166 Query: 169 GEKVVSGGKDRALKLW 122 G+K+ SG K+ + LW Sbjct: 167 GKKLASGCKNGQILLW 182 Score = 49.7 bits (117), Expect = 5e-06 Identities = 46/181 (25%), Positives = 72/181 (39%), Gaps = 43/181 (23%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 S S D ++ +W+ T + + +TGH + V + + DG L SAS D+++K+W G Sbjct: 220 SSSKDGSVRIWDTTAGRCERI-LTGHTQSVTCLRWGGDGL-LYSASQDRTIKVWRAHDGV 277 Query: 355 FVTAFRGHVADVYQISWSADSRL------------------------------------- 287 +GH V ++ S D L Sbjct: 278 LCRTLQGHGHWVNTMALSTDYALRTGAFEPAEASVNPQDLQGSLQELKERALSRYNLMRG 337 Query: 286 -----LLSGSKDSTLKVWD-IRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKL 125 L+SGS D TL +W +K + GH + V +SPD V S D+++KL Sbjct: 338 QGPERLVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKL 397 Query: 124 W 122 W Sbjct: 398 W 398
>NLE1_HUMAN (Q9NVX2) Notchless homolog 1| Length = 484 Score = 218 bits (555), Expect = 8e-57 Identities = 97/138 (70%), Positives = 118/138 (85%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SGSDDFT+FLW P K+P RMTGHQ ++N V FSPD + +ASASFDKS+KLW+G TGK Sbjct: 345 SGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRTGK 404 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 ++ + RGHVA VYQI+WSADSRLL+SGS DSTLKVWD++A+KL DLPGHADEVYAVDWS Sbjct: 405 YLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWS 464 Query: 175 PDGEKVVSGGKDRALKLW 122 PDG++V SGGKD+ L++W Sbjct: 465 PDGQRVASGGKDKCLRIW 482 Score = 79.0 bits (193), Expect = 8e-15 Identities = 47/144 (32%), Positives = 76/144 (52%), Gaps = 6/144 (4%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SGS D T+ W+ + ++ P GH+ V + +SPDG+ LAS + + LW+ TGK Sbjct: 130 SGSGDTTVRFWDLS-TETPHFTCKGHRHWVLSISWSPDGKKLASGCKNGQILLWDPSTGK 188 Query: 355 FV-TAFRGHVADVYQISW-----SADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEV 194 V GH + +SW + + R + S SKD ++++WD A + ++ L GH V Sbjct: 189 QVGRTLAGHSKWITGLSWEPLHANPECRYVASSSKDGSVRIWDTTAGRCERILTGHTQSV 248 Query: 193 YAVDWSPDGEKVVSGGKDRALKLW 122 + W DG + S +DR +K+W Sbjct: 249 TCLRWGGDG-LLYSASQDRTIKVW 271 Score = 72.0 bits (175), Expect = 1e-12 Identities = 40/122 (32%), Positives = 65/122 (53%), Gaps = 6/122 (4%) Frame = -2 Query: 469 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 290 + GH + V V FSP G++LAS S D +V+ W+ T +GH V ISWS D + Sbjct: 109 LEGHSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISWSPDGK 168 Query: 289 LLLSGSKDSTLKVWD-IRARKLKQDLPGHADEVYAVDW-----SPDGEKVVSGGKDRALK 128 L SG K+ + +WD +++ + L GH+ + + W +P+ V S KD +++ Sbjct: 169 KLASGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHANPECRYVASSSKDGSVR 228 Query: 127 LW 122 +W Sbjct: 229 IW 230 Score = 67.8 bits (164), Expect = 2e-11 Identities = 40/127 (31%), Positives = 63/127 (49%), Gaps = 5/127 (3%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHV-----YFSPDGQWLASASFDKSVKLWN 371 SG + + LW+P+ KQ + GH K + + + +P+ +++AS+S D SV++W+ Sbjct: 172 SGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHANPECRYVASSSKDGSVRIWD 231 Query: 370 GITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVY 191 G+ GH V + W D LL S S+D T+KVW L + L GH V Sbjct: 232 TTAGRCERILTGHTQSVTCLRWGGDG-LLYSASQDRTIKVWRAHDGVLCRTLQGHGHWVN 290 Query: 190 AVDWSPD 170 + S D Sbjct: 291 TMALSTD 297 Score = 58.5 bits (140), Expect = 1e-08 Identities = 26/76 (34%), Positives = 42/76 (55%) Frame = -2 Query: 349 TAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPD 170 ++ GH V +++S + L SGS D+T++ WD+ GH V ++ WSPD Sbjct: 107 SSLEGHSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISWSPD 166 Query: 169 GEKVVSGGKDRALKLW 122 G+K+ SG K+ + LW Sbjct: 167 GKKLASGCKNGQILLW 182 Score = 49.7 bits (117), Expect = 5e-06 Identities = 46/181 (25%), Positives = 72/181 (39%), Gaps = 43/181 (23%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 S S D ++ +W+ T + + +TGH + V + + DG L SAS D+++K+W G Sbjct: 220 SSSKDGSVRIWDTTAGRCERI-LTGHTQSVTCLRWGGDGL-LYSASQDRTIKVWRAHDGV 277 Query: 355 FVTAFRGHVADVYQISWSADSRL------------------------------------- 287 +GH V ++ S D L Sbjct: 278 LCRTLQGHGHWVNTMALSTDYALRTGAFEPAEASVNPQDLQGSLQELKERALSRYNLVRG 337 Query: 286 -----LLSGSKDSTLKVWD-IRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKL 125 L+SGS D TL +W +K + GH + V +SPD V S D+++KL Sbjct: 338 QGPERLVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKL 397 Query: 124 W 122 W Sbjct: 398 W 398
>YCW2_YEAST (P25382) Hypothetical WD-repeat protein YCR072C| Length = 515 Score = 210 bits (534), Expect = 2e-54 Identities = 93/138 (67%), Positives = 115/138 (83%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 + SDD+TMFLW P S +P ARMTGHQK+VNHV FSPDG+++ SASFD S+KLW+G GK Sbjct: 376 TASDDYTMFLWNPLKSTKPIARMTGHQKLVNHVAFSPDGRYIVSASFDNSIKLWDGRDGK 435 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 F++ FRGHVA VYQ++WS+D RLL+S SKD+TLKVWD+R RKL DLPGH DEVY VDWS Sbjct: 436 FISTFRGHVASVYQVAWSSDCRLLVSCSKDTTLKVWDVRTRKLSVDLPGHKDEVYTVDWS 495 Query: 175 PDGEKVVSGGKDRALKLW 122 DG++V SGGKD+ ++LW Sbjct: 496 VDGKRVCSGGKDKMVRLW 513 Score = 80.5 bits (197), Expect = 3e-15 Identities = 46/146 (31%), Positives = 76/146 (52%), Gaps = 8/146 (5%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 +G+ D T +W+ ++ P + GH V V +SPDG+ +A+ S D +++LW+ +G+ Sbjct: 161 TGAGDNTARIWDCD-TQTPMHTLKGHYNWVLCVSWSPDGEVIATGSMDNTIRLWDPKSGQ 219 Query: 355 FV-TAFRGHVADVYQISWS-------ADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHAD 200 + A RGH + +SW L S SKD T+K+WD +R + + GH + Sbjct: 220 CLGDALRGHSKWITSLSWEPIHLVKPGSKPRLASSSKDGTIKIWDTVSRVCQYTMSGHTN 279 Query: 199 EVYAVDWSPDGEKVVSGGKDRALKLW 122 V V W G + SG DR +++W Sbjct: 280 SVSCVKWGGQG-LLYSGSHDRTVRVW 304 Score = 57.8 bits (138), Expect = 2e-08 Identities = 31/125 (24%), Positives = 62/125 (49%), Gaps = 9/125 (7%) Frame = -2 Query: 469 MTGHQKVVNHVYFSPD-GQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADS 293 + GH + F+P + + + D + ++W+ T + +GH V +SWS D Sbjct: 139 IAGHGSTILCSAFAPHTSSRMVTGAGDNTARIWDCDTQTPMHTLKGHYNWVLCVSWSPDG 198 Query: 292 RLLLSGSKDSTLKVWDIRARKLKQD-LPGHADEVYAVDWSP-------DGEKVVSGGKDR 137 ++ +GS D+T+++WD ++ + D L GH+ + ++ W P ++ S KD Sbjct: 199 EVIATGSMDNTIRLWDPKSGQCLGDALRGHSKWITSLSWEPIHLVKPGSKPRLASSSKDG 258 Query: 136 ALKLW 122 +K+W Sbjct: 259 TIKIW 263 Score = 56.2 bits (134), Expect = 6e-08 Identities = 39/130 (30%), Positives = 61/130 (46%), Gaps = 8/130 (6%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSP-------DGQWLASASFDKSVKL 377 +GS D T+ LW+P + + GH K + + + P LAS+S D ++K+ Sbjct: 203 TGSMDNTIRLWDPKSGQCLGDALRGHSKWITSLSWEPIHLVKPGSKPRLASSSKDGTIKI 262 Query: 376 WNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRAR-KLKQDLPGHAD 200 W+ ++ GH V + W LL SGS D T++VWDI ++ + L HA Sbjct: 263 WDTVSRVCQYTMSGHTNSVSCVKWGGQG-LLYSGSHDRTVRVWDINSQGRCINILKSHAH 321 Query: 199 EVYAVDWSPD 170 V + S D Sbjct: 322 WVNHLSLSTD 331 Score = 53.5 bits (127), Expect = 4e-07 Identities = 24/77 (31%), Positives = 43/77 (55%), Gaps = 1/77 (1%) Frame = -2 Query: 349 TAFRGHVADVYQISWSAD-SRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSP 173 +A GH + + +++ S +++G+ D+T ++WD + L GH + V V WSP Sbjct: 137 SAIAGHGSTILCSAFAPHTSSRMVTGAGDNTARIWDCDTQTPMHTLKGHYNWVLCVSWSP 196 Query: 172 DGEKVVSGGKDRALKLW 122 DGE + +G D ++LW Sbjct: 197 DGEVIATGSMDNTIRLW 213
>Y2124_ANASP (Q8YV57) Hypothetical WD-repeat protein all2124| Length = 1683 Score = 117 bits (294), Expect = 2e-26 Identities = 58/138 (42%), Positives = 88/138 (63%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SG D T+ LW+ + K +TGH++ VN+VYFSPDG+ LASAS D S+KLW+ +G+ Sbjct: 1130 SGGSDKTIKLWQTSDGTLLKT-ITGHEQTVNNVYFSPDGKNLASASSDHSIKLWDTTSGQ 1188 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 + GH A V + +S D + + +GS+D T+K+W + KL + L GH D V ++ +S Sbjct: 1189 LLMTLTGHSAGVITVRFSPDGQTIAAGSEDKTVKLWHRQDGKLLKTLNGHQDWVNSLSFS 1248 Query: 175 PDGEKVVSGGKDRALKLW 122 PDG+ + S D+ +KLW Sbjct: 1249 PDGKTLASASADKTIKLW 1266 Score = 116 bits (291), Expect = 3e-26 Identities = 58/138 (42%), Positives = 84/138 (60%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 S + D T+ +W K K + GH VN V FSPDG+ LASAS D +VKLWN GK Sbjct: 1421 SANADKTVKIWRVRDGKALKT-LIGHDNEVNKVNFSPDGKTLASASRDNTVKLWNVSDGK 1479 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 F +GH +V+ +S+S D +++ S S D T+++WD + L + LP H D VY+V+++ Sbjct: 1480 FKKTLKGHTDEVFWVSFSPDGKIIASASADKTIRLWDSFSGNLIKSLPAHNDLVYSVNFN 1539 Query: 175 PDGEKVVSGGKDRALKLW 122 PDG + S D+ +KLW Sbjct: 1540 PDGSMLASTSADKTVKLW 1557 Score = 109 bits (273), Expect = 4e-24 Identities = 59/138 (42%), Positives = 81/138 (58%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 S S D ++ LW+ T S Q +TGH V V FSPDGQ +A+ S DK+VKLW+ GK Sbjct: 1172 SASSDHSIKLWDTT-SGQLLMTLTGHSAGVITVRFSPDGQTIAAGSEDKTVKLWHRQDGK 1230 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 + GH V +S+S D + L S S D T+K+W I KL + L GH D V+ V++S Sbjct: 1231 LLKTLNGHQDWVNSLSFSPDGKTLASASADKTIKLWRIADGKLVKTLKGHNDSVWDVNFS 1290 Query: 175 PDGEKVVSGGKDRALKLW 122 DG+ + S +D +KLW Sbjct: 1291 SDGKAIASASRDNTIKLW 1308 Score = 108 bits (270), Expect = 9e-24 Identities = 55/138 (39%), Positives = 84/138 (60%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 +GS+D T+ LW K K + GHQ VN + FSPDG+ LASAS DK++KLW GK Sbjct: 1214 AGSEDKTVKLWHRQDGKLLKT-LNGHQDWVNSLSFSPDGKTLASASADKTIKLWRIADGK 1272 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 V +GH V+ +++S+D + + S S+D+T+K+W+ +L + GH+ VYAV++ Sbjct: 1273 LVKTLKGHNDSVWDVNFSSDGKAIASASRDNTIKLWNRHGIEL-ETFTGHSGGVYAVNFL 1331 Query: 175 PDGEKVVSGGKDRALKLW 122 PD + S D ++LW Sbjct: 1332 PDSNIIASASLDNTIRLW 1349 Score = 100 bits (248), Expect = 3e-21 Identities = 52/138 (37%), Positives = 76/138 (55%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SGS D T+ LW + + GH+ V V FSPDGQ +AS DK++KLW G Sbjct: 1089 SGSLDKTIKLWSR--DGRLFRTLNGHEDAVYSVSFSPDGQTIASGGSDKTIKLWQTSDGT 1146 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 + GH V + +S D + L S S D ++K+WD + +L L GH+ V V +S Sbjct: 1147 LLKTITGHEQTVNNVYFSPDGKNLASASSDHSIKLWDTTSGQLLMTLTGHSAGVITVRFS 1206 Query: 175 PDGEKVVSGGKDRALKLW 122 PDG+ + +G +D+ +KLW Sbjct: 1207 PDGQTIAAGSEDKTVKLW 1224 Score = 98.6 bits (244), Expect = 1e-20 Identities = 50/138 (36%), Positives = 78/138 (56%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 S S D T+ LW + K K + GH V V FSPDG+ +ASAS DK+++LW+ +G Sbjct: 1463 SASRDNTVKLWNVSDGKFKKT-LKGHTDEVFWVSFSPDGKIIASASADKTIRLWDSFSGN 1521 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 + + H VY ++++ D +L S S D T+K+W L GH++ VY+ +S Sbjct: 1522 LIKSLPAHNDLVYSVNFNPDGSMLASTSADKTVKLWRSHDGHLLHTFSGHSNVVYSSSFS 1581 Query: 175 PDGEKVVSGGKDRALKLW 122 PDG + S +D+ +K+W Sbjct: 1582 PDGRYIASASEDKTVKIW 1599 Score = 97.4 bits (241), Expect = 2e-20 Identities = 55/138 (39%), Positives = 74/138 (53%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 S S D T+ LW+ K+ + H +V V F+PDG LAS S DK+VKLW G Sbjct: 1505 SASADKTIRLWDSFSGNLIKS-LPAHNDLVYSVNFNPDGSMLASTSADKTVKLWRSHDGH 1563 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 + F GH VY S+S D R + S S+D T+K+W I L LP H V + +S Sbjct: 1564 LLHTFSGHSNVVYSSSFSPDGRYIASASEDKTVKIWQIDGH-LLTTLPQHQAGVMSAIFS 1622 Query: 175 PDGEKVVSGGKDRALKLW 122 PDG+ ++SG D K+W Sbjct: 1623 PDGKTLISGSLDTTTKIW 1640 Score = 97.4 bits (241), Expect = 2e-20 Identities = 43/111 (38%), Positives = 71/111 (63%) Frame = -2 Query: 454 KVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSG 275 K + + F+P G +ASA+ DK+VK+W GK + GH +V ++++S D + L S Sbjct: 1405 KAIYGISFTPQGDLIASANADKTVKIWRVRDGKALKTLIGHDNEVNKVNFSPDGKTLASA 1464 Query: 274 SKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 S+D+T+K+W++ K K+ L GH DEV+ V +SPDG+ + S D+ ++LW Sbjct: 1465 SRDNTVKLWNVSDGKFKKTLKGHTDEVFWVSFSPDGKIIASASADKTIRLW 1515 Score = 91.7 bits (226), Expect = 1e-18 Identities = 46/129 (35%), Positives = 69/129 (53%) Frame = -2 Query: 508 LWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHV 329 L + Q + R+ GH+ V + S DGQ +AS S DK++KLW+ G+ GH Sbjct: 1055 LQQALFEMQERNRLEGHKDGVISISISRDGQTIASGSLDKTIKLWSR-DGRLFRTLNGHE 1113 Query: 328 ADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSG 149 VY +S+S D + + SG D T+K+W L + + GH V V +SPDG+ + S Sbjct: 1114 DAVYSVSFSPDGQTIASGGSDKTIKLWQTSDGTLLKTITGHEQTVNNVYFSPDGKNLASA 1173 Query: 148 GKDRALKLW 122 D ++KLW Sbjct: 1174 SSDHSIKLW 1182 Score = 68.9 bits (167), Expect = 8e-12 Identities = 41/104 (39%), Positives = 58/104 (55%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 S S D T+ LW + +GH VV FSPDG+++ASAS DK+VK+W I G Sbjct: 1547 STSADKTVKLWR-SHDGHLLHTFSGHSNVVYSSSFSPDGRYIASASEDKTVKIWQ-IDGH 1604 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLK 224 +T H A V +S D + L+SGS D+T K+W +++ K Sbjct: 1605 LLTTLPQHQAGVMSAIFSPDGKTLISGSLDTTTKIWRFDSQQAK 1648 Score = 66.2 bits (160), Expect = 5e-11 Identities = 39/138 (28%), Positives = 68/138 (49%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 S S D T+ LW + TGH V V F PD +ASAS D +++LW Sbjct: 1298 SASRDNTIKLWNRHGIELET--FTGHSGGVYAVNFLPDSNIIASASLDNTIRLWQRPLIS 1355 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 + G+ + VY +S+ D ++ + D +++W + L + LPG+ +Y + ++ Sbjct: 1356 PLEVLAGN-SGVYAVSFLHDGSIIATAGADGNIQLWHSQDGSLLKTLPGN-KAIYGISFT 1413 Query: 175 PDGEKVVSGGKDRALKLW 122 P G+ + S D+ +K+W Sbjct: 1414 PQGDLIASANADKTVKIW 1431
>WDS_DROME (Q9V3J8) Protein will die slowly| Length = 361 Score = 117 bits (293), Expect = 2e-26 Identities = 51/119 (42%), Positives = 77/119 (64%) Frame = -2 Query: 478 KARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSA 299 K + GH K V+ V FSP+G+WLAS+S DK +K+W GKF GH + ++WS+ Sbjct: 65 KFTLAGHTKAVSAVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSS 124 Query: 298 DSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 DSRLL+SGS D TLKVW++ K + L GH++ V+ +++P +VSG D ++++W Sbjct: 125 DSRLLVSGSDDKTLKVWELSTGKSLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIW 183 Score = 80.9 bits (198), Expect = 2e-15 Identities = 46/139 (33%), Positives = 73/139 (52%), Gaps = 1/139 (0%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SGSDD T+ +WE + K K + GH V F+P + S SFD+SV++W+ TGK Sbjct: 131 SGSDDKTLKVWELSTGKSLKT-LKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVRTGK 189 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARK-LKQDLPGHADEVYAVDW 179 + H V + ++ D L++S S D ++WD + + LK + V V + Sbjct: 190 CLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKF 249 Query: 178 SPDGEKVVSGGKDRALKLW 122 SP+G+ +++ D LKLW Sbjct: 250 SPNGKYILAATLDNTLKLW 268 Score = 71.6 bits (174), Expect = 1e-12 Identities = 39/143 (27%), Positives = 74/143 (51%), Gaps = 5/143 (3%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 S S D +W+ + K + V+ V FSP+G+++ +A+ D ++KLW+ GK Sbjct: 215 SSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGK 274 Query: 355 FVTAFRGHVADVYQISWS---ADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAV 185 + + GH + Y I + + ++SGS+D+ + +W+++++++ Q L GH D V Sbjct: 275 CLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNMVYIWNLQSKEVVQKLQGHTDTVLCT 334 Query: 184 DWSPDGEKVVSGG--KDRALKLW 122 P + S D+ +KLW Sbjct: 335 ACHPTENIIASAALENDKTIKLW 357 Score = 35.8 bits (81), Expect = 0.078 Identities = 16/36 (44%), Positives = 22/36 (61%) Frame = -2 Query: 229 LKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 LK L GH V AV +SP+GE + S D+ +K+W Sbjct: 64 LKFTLAGHTKAVSAVKFSPNGEWLASSSADKLIKIW 99
>WDR5_MOUSE (P61965) WD-repeat protein 5 (BMP2-induced 3-kb gene protein)| (WD-repeat protein BIG-3) Length = 334 Score = 115 bits (289), Expect = 6e-26 Identities = 49/119 (41%), Positives = 76/119 (63%) Frame = -2 Query: 478 KARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSA 299 K + GH K V+ V FSP+G+WLAS+S DK +K+W GKF GH + ++WS+ Sbjct: 38 KFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSS 97 Query: 298 DSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 DS LL+S S D TLK+WD+ + K + L GH++ V+ +++P +VSG D ++++W Sbjct: 98 DSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIW 156 Score = 89.7 bits (221), Expect = 5e-18 Identities = 46/138 (33%), Positives = 80/138 (57%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 S S D + +W K K ++GH+ ++ V +S D L SAS DK++K+W+ +GK Sbjct: 62 SSSADKLIKIWGAYDGKFEKT-ISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGK 120 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 + +GH V+ +++ S L++SGS D ++++WD++ K + LP H+D V AV ++ Sbjct: 121 CLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFN 180 Query: 175 PDGEKVVSGGKDRALKLW 122 DG +VS D ++W Sbjct: 181 RDGSLIVSSSYDGLCRIW 198 Score = 76.6 bits (187), Expect = 4e-14 Identities = 44/139 (31%), Positives = 72/139 (51%), Gaps = 1/139 (0%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 S SDD T+ +W+ + K K + GH V F+P + S SFD+SV++W+ TGK Sbjct: 104 SASDDKTLKIWDVSSGKCLKT-LKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGK 162 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARK-LKQDLPGHADEVYAVDW 179 + H V + ++ D L++S S D ++WD + + LK + V V + Sbjct: 163 CLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKF 222 Query: 178 SPDGEKVVSGGKDRALKLW 122 SP+G+ +++ D LKLW Sbjct: 223 SPNGKYILAATLDNTLKLW 241 Score = 71.6 bits (174), Expect = 1e-12 Identities = 39/143 (27%), Positives = 74/143 (51%), Gaps = 5/143 (3%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 S S D +W+ + K + V+ V FSP+G+++ +A+ D ++KLW+ GK Sbjct: 188 SSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGK 247 Query: 355 FVTAFRGHVADVYQISWS---ADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAV 185 + + GH + Y I + + ++SGS+D+ + +W+++ +++ Q L GH D V + Sbjct: 248 CLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVIST 307 Query: 184 DWSPDGEKVVSGG--KDRALKLW 122 P + S D+ +KLW Sbjct: 308 ACHPTENIIASAALENDKTIKLW 330 Score = 34.7 bits (78), Expect = 0.17 Identities = 15/36 (41%), Positives = 22/36 (61%) Frame = -2 Query: 229 LKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 LK L GH V +V +SP+GE + S D+ +K+W Sbjct: 37 LKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIW 72
>WDR5_HUMAN (P61964) WD-repeat protein 5 (BMP2-induced 3-kb gene protein)| Length = 334 Score = 115 bits (289), Expect = 6e-26 Identities = 49/119 (41%), Positives = 76/119 (63%) Frame = -2 Query: 478 KARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSA 299 K + GH K V+ V FSP+G+WLAS+S DK +K+W GKF GH + ++WS+ Sbjct: 38 KFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSS 97 Query: 298 DSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 DS LL+S S D TLK+WD+ + K + L GH++ V+ +++P +VSG D ++++W Sbjct: 98 DSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIW 156 Score = 89.7 bits (221), Expect = 5e-18 Identities = 46/138 (33%), Positives = 80/138 (57%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 S S D + +W K K ++GH+ ++ V +S D L SAS DK++K+W+ +GK Sbjct: 62 SSSADKLIKIWGAYDGKFEKT-ISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGK 120 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 + +GH V+ +++ S L++SGS D ++++WD++ K + LP H+D V AV ++ Sbjct: 121 CLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFN 180 Query: 175 PDGEKVVSGGKDRALKLW 122 DG +VS D ++W Sbjct: 181 RDGSLIVSSSYDGLCRIW 198 Score = 76.6 bits (187), Expect = 4e-14 Identities = 44/139 (31%), Positives = 72/139 (51%), Gaps = 1/139 (0%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 S SDD T+ +W+ + K K + GH V F+P + S SFD+SV++W+ TGK Sbjct: 104 SASDDKTLKIWDVSSGKCLKT-LKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGK 162 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARK-LKQDLPGHADEVYAVDW 179 + H V + ++ D L++S S D ++WD + + LK + V V + Sbjct: 163 CLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKF 222 Query: 178 SPDGEKVVSGGKDRALKLW 122 SP+G+ +++ D LKLW Sbjct: 223 SPNGKYILAATLDNTLKLW 241 Score = 71.6 bits (174), Expect = 1e-12 Identities = 39/143 (27%), Positives = 74/143 (51%), Gaps = 5/143 (3%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 S S D +W+ + K + V+ V FSP+G+++ +A+ D ++KLW+ GK Sbjct: 188 SSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGK 247 Query: 355 FVTAFRGHVADVYQISWS---ADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAV 185 + + GH + Y I + + ++SGS+D+ + +W+++ +++ Q L GH D V + Sbjct: 248 CLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVIST 307 Query: 184 DWSPDGEKVVSGG--KDRALKLW 122 P + S D+ +KLW Sbjct: 308 ACHPTENIIASAALENDKTIKLW 330 Score = 34.7 bits (78), Expect = 0.17 Identities = 15/36 (41%), Positives = 22/36 (61%) Frame = -2 Query: 229 LKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 LK L GH V +V +SP+GE + S D+ +K+W Sbjct: 37 LKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIW 72
>HETE1_PODAN (Q00808) Vegetatible incompatibility protein HET-E-1| Length = 1356 Score = 111 bits (277), Expect = 1e-24 Identities = 55/138 (39%), Positives = 82/138 (59%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SGSDD T+ +W+ T S + GH V V FSPDGQ +AS S D ++K+W+ ++G Sbjct: 1026 SGSDDKTIKIWD-TASGTCTQTLEGHGGWVQSVVFSPDGQRVASGSDDHTIKIWDAVSGT 1084 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 GH V+ +++S D + + SGS D T+K+WD + Q L GH V++V +S Sbjct: 1085 CTQTLEGHGDSVWSVAFSPDGQRVASGSIDGTIKIWDAASGTCTQTLEGHGGWVHSVAFS 1144 Query: 175 PDGEKVVSGGKDRALKLW 122 PDG++V SG D +K+W Sbjct: 1145 PDGQRVASGSIDGTIKIW 1162 Score = 111 bits (277), Expect = 1e-24 Identities = 55/138 (39%), Positives = 80/138 (57%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SGSDD T+ +W+ S + GH V V FSPDGQ +AS S DK++K+W+ +G Sbjct: 942 SGSDDHTIKIWDAA-SGTCTQTLEGHGSSVLSVAFSPDGQRVASGSGDKTIKIWDTASGT 1000 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 GH V+ +++S D + + SGS D T+K+WD + Q L GH V +V +S Sbjct: 1001 CTQTLEGHGGSVWSVAFSPDGQRVASGSDDKTIKIWDTASGTCTQTLEGHGGWVQSVVFS 1060 Query: 175 PDGEKVVSGGKDRALKLW 122 PDG++V SG D +K+W Sbjct: 1061 PDGQRVASGSDDHTIKIW 1078 Score = 111 bits (277), Expect = 1e-24 Identities = 54/138 (39%), Positives = 81/138 (58%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SGSDD T+ +W+ S + GH V V FSPDGQ +AS S D ++K+W+ +G Sbjct: 900 SGSDDKTIKIWDAA-SGTCTQTLEGHGGRVQSVAFSPDGQRVASGSDDHTIKIWDAASGT 958 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 GH + V +++S D + + SGS D T+K+WD + Q L GH V++V +S Sbjct: 959 CTQTLEGHGSSVLSVAFSPDGQRVASGSGDKTIKIWDTASGTCTQTLEGHGGSVWSVAFS 1018 Query: 175 PDGEKVVSGGKDRALKLW 122 PDG++V SG D+ +K+W Sbjct: 1019 PDGQRVASGSDDKTIKIW 1036 Score = 110 bits (275), Expect = 2e-24 Identities = 54/138 (39%), Positives = 81/138 (58%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SGSDD T+ +W+ +S + GH V V FSPDGQ +AS S D ++K+W+ +G Sbjct: 1068 SGSDDHTIKIWD-AVSGTCTQTLEGHGDSVWSVAFSPDGQRVASGSIDGTIKIWDAASGT 1126 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 GH V+ +++S D + + SGS D T+K+WD + Q L GH V +V +S Sbjct: 1127 CTQTLEGHGGWVHSVAFSPDGQRVASGSIDGTIKIWDAASGTCTQTLEGHGGWVQSVAFS 1186 Query: 175 PDGEKVVSGGKDRALKLW 122 PDG++V SG D+ +K+W Sbjct: 1187 PDGQRVASGSSDKTIKIW 1204 Score = 108 bits (269), Expect = 1e-23 Identities = 54/138 (39%), Positives = 80/138 (57%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SGSDD T+ +W+ T S + GH V V FSPD + +AS S DK++K+W+ +G Sbjct: 858 SGSDDKTIKIWD-TASGTGTQTLEGHGGSVWSVAFSPDRERVASGSDDKTIKIWDAASGT 916 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 GH V +++S D + + SGS D T+K+WD + Q L GH V +V +S Sbjct: 917 CTQTLEGHGGRVQSVAFSPDGQRVASGSDDHTIKIWDAASGTCTQTLEGHGSSVLSVAFS 976 Query: 175 PDGEKVVSGGKDRALKLW 122 PDG++V SG D+ +K+W Sbjct: 977 PDGQRVASGSGDKTIKIW 994 Score = 107 bits (267), Expect = 2e-23 Identities = 56/138 (40%), Positives = 80/138 (57%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SGS D T+ +W+ T S + GH V V FSPDGQ +AS S DK++K+W+ +G Sbjct: 984 SGSGDKTIKIWD-TASGTCTQTLEGHGGSVWSVAFSPDGQRVASGSDDKTIKIWDTASGT 1042 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 GH V + +S D + + SGS D T+K+WD + Q L GH D V++V +S Sbjct: 1043 CTQTLEGHGGWVQSVVFSPDGQRVASGSDDHTIKIWDAVSGTCTQTLEGHGDSVWSVAFS 1102 Query: 175 PDGEKVVSGGKDRALKLW 122 PDG++V SG D +K+W Sbjct: 1103 PDGQRVASGSIDGTIKIW 1120 Score = 105 bits (261), Expect = 1e-22 Identities = 53/138 (38%), Positives = 78/138 (56%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SGS D T+ +W+ S + GH V+ V FSPDGQ +AS S D ++K+W+ +G Sbjct: 1110 SGSIDGTIKIWDAA-SGTCTQTLEGHGGWVHSVAFSPDGQRVASGSIDGTIKIWDAASGT 1168 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 GH V +++S D + + SGS D T+K+WD + Q L GH V +V +S Sbjct: 1169 CTQTLEGHGGWVQSVAFSPDGQRVASGSSDKTIKIWDTASGTCTQTLEGHGGWVQSVAFS 1228 Query: 175 PDGEKVVSGGKDRALKLW 122 PDG++V SG D +K+W Sbjct: 1229 PDGQRVASGSSDNTIKIW 1246 Score = 99.0 bits (245), Expect = 7e-21 Identities = 46/116 (39%), Positives = 67/116 (57%) Frame = -2 Query: 469 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 290 + GH V V FS DGQ +AS S DK++K+W+ +G GH V+ +++S D Sbjct: 837 LEGHGSSVLSVAFSADGQRVASGSDDKTIKIWDTASGTGTQTLEGHGGSVWSVAFSPDRE 896 Query: 289 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 + SGS D T+K+WD + Q L GH V +V +SPDG++V SG D +K+W Sbjct: 897 RVASGSDDKTIKIWDAASGTCTQTLEGHGGRVQSVAFSPDGQRVASGSDDHTIKIW 952 Score = 74.3 bits (181), Expect = 2e-13 Identities = 40/107 (37%), Positives = 59/107 (55%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SGS D T+ +W+ S + GH V V FSPDGQ +AS S DK++K+W+ +G Sbjct: 1152 SGSIDGTIKIWDAA-SGTCTQTLEGHGGWVQSVAFSPDGQRVASGSSDKTIKIWDTASGT 1210 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDL 215 GH V +++S D + + SGS D+T+K+WD + Q L Sbjct: 1211 CTQTLEGHGGWVQSVAFSPDGQRVASGSSDNTIKIWDTASGTCTQTL 1257 Score = 41.2 bits (95), Expect = 0.002 Identities = 18/48 (37%), Positives = 27/48 (56%) Frame = -2 Query: 265 STLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 ST+ V + Q L GH V +V +S DG++V SG D+ +K+W Sbjct: 821 STISVVEAEWNACTQTLEGHGSSVLSVAFSADGQRVASGSDDKTIKIW 868
>YY46_ANASP (Q8YRI1) Hypothetical WD-repeat protein alr3466| Length = 1526 Score = 107 bits (266), Expect = 3e-23 Identities = 56/138 (40%), Positives = 80/138 (57%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SGS D T+ LWE SK GH VN V F+PDG LAS S DK+V+LW+ + K Sbjct: 1217 SGSSDQTVRLWEINSSKC-LCTFQGHTSWVNSVVFNPDGSMLASGSSDKTVRLWDISSSK 1275 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 + F+GH V ++++ D +L SGS D T+++W+I + K GH V +V +S Sbjct: 1276 CLHTFQGHTNWVNSVAFNPDGSMLASGSGDQTVRLWEISSSKCLHTFQGHTSWVSSVTFS 1335 Query: 175 PDGEKVVSGGKDRALKLW 122 PDG + SG D+ ++LW Sbjct: 1336 PDGTMLASGSDDQTVRLW 1353 Score = 104 bits (259), Expect = 2e-22 Identities = 54/138 (39%), Positives = 82/138 (59%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SGS D T+ LW+ + SK + GH VN V F+PDG LAS S D++V+LW + K Sbjct: 1175 SGSGDQTVRLWDISSSKCLYI-LQGHTSWVNSVVFNPDGSTLASGSSDQTVRLWEINSSK 1233 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 + F+GH + V + ++ D +L SGS D T+++WDI + K GH + V +V ++ Sbjct: 1234 CLCTFQGHTSWVNSVVFNPDGSMLASGSSDKTVRLWDISSSKCLHTFQGHTNWVNSVAFN 1293 Query: 175 PDGEKVVSGGKDRALKLW 122 PDG + SG D+ ++LW Sbjct: 1294 PDGSMLASGSGDQTVRLW 1311 Score = 100 bits (248), Expect = 3e-21 Identities = 56/138 (40%), Positives = 81/138 (58%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SGS D T+ LWE + SK GH V+ V FSPDG LAS S D++V+LW+ +G+ Sbjct: 1301 SGSGDQTVRLWEISSSKCLHT-FQGHTSWVSSVTFSPDGTMLASGSDDQTVRLWSISSGE 1359 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 + F GH V + +S D +L SGS D T+++W I + K L GH + V ++ +S Sbjct: 1360 CLYTFLGHTNWVGSVIFSPDGAILASGSGDQTVRLWSISSGKCLYTLQGHNNWVGSIVFS 1419 Query: 175 PDGEKVVSGGKDRALKLW 122 PDG + SG D+ ++LW Sbjct: 1420 PDGTLLASGSDDQTVRLW 1437 Score = 100 bits (248), Expect = 3e-21 Identities = 54/138 (39%), Positives = 81/138 (58%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SGS D T+ LW+ + SK GH VN V F+PDG LAS S D++V+LW + K Sbjct: 1259 SGSSDKTVRLWDISSSKCLHT-FQGHTNWVNSVAFNPDGSMLASGSGDQTVRLWEISSSK 1317 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 + F+GH + V +++S D +L SGS D T+++W I + + GH + V +V +S Sbjct: 1318 CLHTFQGHTSWVSSVTFSPDGTMLASGSDDQTVRLWSISSGECLYTFLGHTNWVGSVIFS 1377 Query: 175 PDGEKVVSGGKDRALKLW 122 PDG + SG D+ ++LW Sbjct: 1378 PDGAILASGSGDQTVRLW 1395 Score = 98.2 bits (243), Expect = 1e-20 Identities = 52/138 (37%), Positives = 81/138 (58%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SGSDD T+ LW+ + S Q GH V V FSP+ LAS S D++V+LW+ +G+ Sbjct: 923 SGSDDQTVRLWDIS-SGQCLKTFKGHTSRVRSVVFSPNSLMLASGSSDQTVRLWDISSGE 981 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 + F+GH VY ++++ D +L +GS D T+++WDI + + GH V +V +S Sbjct: 982 CLYIFQGHTGWVYSVAFNLDGSMLATGSGDQTVRLWDISSSQCFYIFQGHTSCVRSVVFS 1041 Query: 175 PDGEKVVSGGKDRALKLW 122 DG + SG D+ ++LW Sbjct: 1042 SDGAMLASGSDDQTVRLW 1059 Score = 97.4 bits (241), Expect = 2e-20 Identities = 57/138 (41%), Positives = 79/138 (57%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SGSDD T+ LW + S + GH V V FSPDG LAS S D++V+LW+ +GK Sbjct: 1343 SGSDDQTVRLWSIS-SGECLYTFLGHTNWVGSVIFSPDGAILASGSGDQTVRLWSISSGK 1401 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 + +GH V I +S D LL SGS D T+++W+I + + L GH + V +V +S Sbjct: 1402 CLYTLQGHNNWVGSIVFSPDGTLLASGSDDQTVRLWNISSGECLYTLHGHINSVRSVAFS 1461 Query: 175 PDGEKVVSGGKDRALKLW 122 DG + SG D +KLW Sbjct: 1462 SDGLILASGSDDETIKLW 1479 Score = 97.1 bits (240), Expect = 3e-20 Identities = 51/138 (36%), Positives = 80/138 (57%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 +GS D + LW+ + SK+ + GH VN V FSPDG LAS S D++V+LW+ + K Sbjct: 1133 NGSSDQIVRLWDIS-SKKCLYTLQGHTNWVNAVAFSPDGATLASGSGDQTVRLWDISSSK 1191 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 + +GH + V + ++ D L SGS D T+++W+I + K GH V +V ++ Sbjct: 1192 CLYILQGHTSWVNSVVFNPDGSTLASGSSDQTVRLWEINSSKCLCTFQGHTSWVNSVVFN 1251 Query: 175 PDGEKVVSGGKDRALKLW 122 PDG + SG D+ ++LW Sbjct: 1252 PDGSMLASGSSDKTVRLW 1269 Score = 94.7 bits (234), Expect = 1e-19 Identities = 52/138 (37%), Positives = 79/138 (57%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SGSDD T+ LW+ + S + GH V V FSPDG LAS D+ V+LW+ +G Sbjct: 1049 SGSDDQTVRLWDIS-SGNCLYTLQGHTSCVRSVVFSPDGAMLASGGDDQIVRLWDISSGN 1107 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 + +G+ + V + +S + L +GS D +++WDI ++K L GH + V AV +S Sbjct: 1108 CLYTLQGYTSWVRFLVFSPNGVTLANGSSDQIVRLWDISSKKCLYTLQGHTNWVNAVAFS 1167 Query: 175 PDGEKVVSGGKDRALKLW 122 PDG + SG D+ ++LW Sbjct: 1168 PDGATLASGSGDQTVRLW 1185 Score = 93.6 bits (231), Expect = 3e-19 Identities = 52/138 (37%), Positives = 80/138 (57%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SGS D T+ LW+ + S + GH V V F+ DG LA+ S D++V+LW+ + + Sbjct: 965 SGSSDQTVRLWDIS-SGECLYIFQGHTGWVYSVAFNLDGSMLATGSGDQTVRLWDISSSQ 1023 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 F+GH + V + +S+D +L SGS D T+++WDI + L GH V +V +S Sbjct: 1024 CFYIFQGHTSCVRSVVFSSDGAMLASGSDDQTVRLWDISSGNCLYTLQGHTSCVRSVVFS 1083 Query: 175 PDGEKVVSGGKDRALKLW 122 PDG + SGG D+ ++LW Sbjct: 1084 PDGAMLASGGDDQIVRLW 1101 Score = 93.2 bits (230), Expect = 4e-19 Identities = 47/128 (36%), Positives = 75/128 (58%) Frame = -2 Query: 505 WEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVA 326 WE K+ GH VN V FS DG+ LAS S D++V+LW+ +G+ + F+GH + Sbjct: 891 WEAATGKE-LLTCKGHNSWVNSVGFSQDGKMLASGSDDQTVRLWDISSGQCLKTFKGHTS 949 Query: 325 DVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGG 146 V + +S +S +L SGS D T+++WDI + + GH VY+V ++ DG + +G Sbjct: 950 RVRSVVFSPNSLMLASGSSDQTVRLWDISSGECLYIFQGHTGWVYSVAFNLDGSMLATGS 1009 Query: 145 KDRALKLW 122 D+ ++LW Sbjct: 1010 GDQTVRLW 1017 Score = 88.6 bits (218), Expect = 1e-17 Identities = 49/138 (35%), Positives = 77/138 (55%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SG DD + LW+ + S + G+ V + FSP+G LA+ S D+ V+LW+ + K Sbjct: 1091 SGGDDQIVRLWDIS-SGNCLYTLQGYTSWVRFLVFSPNGVTLANGSSDQIVRLWDISSKK 1149 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 + +GH V +++S D L SGS D T+++WDI + K L GH V +V ++ Sbjct: 1150 CLYTLQGHTNWVNAVAFSPDGATLASGSGDQTVRLWDISSSKCLYILQGHTSWVNSVVFN 1209 Query: 175 PDGEKVVSGGKDRALKLW 122 PDG + SG D+ ++LW Sbjct: 1210 PDGSTLASGSSDQTVRLW 1227 Score = 85.5 bits (210), Expect = 9e-17 Identities = 47/138 (34%), Positives = 75/138 (54%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 +GS D T+ LW+ + S Q GH V V FS DG LAS S D++V+LW+ +G Sbjct: 1007 TGSGDQTVRLWDIS-SSQCFYIFQGHTSCVRSVVFSSDGAMLASGSDDQTVRLWDISSGN 1065 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 + +GH + V + +S D +L SG D +++WDI + L G+ V + +S Sbjct: 1066 CLYTLQGHTSCVRSVVFSPDGAMLASGGDDQIVRLWDISSGNCLYTLQGYTSWVRFLVFS 1125 Query: 175 PDGEKVVSGGKDRALKLW 122 P+G + +G D+ ++LW Sbjct: 1126 PNGVTLANGSSDQIVRLW 1143 Score = 79.7 bits (195), Expect = 5e-15 Identities = 40/99 (40%), Positives = 60/99 (60%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SGS D T+ LW + K + GH V + FSPDG LAS S D++V+LWN +G+ Sbjct: 1385 SGSGDQTVRLWSISSGKCLYT-LQGHNNWVGSIVFSPDGTLLASGSDDQTVRLWNISSGE 1443 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIR 239 + GH+ V +++S+D +L SGS D T+K+WD++ Sbjct: 1444 CLYTLHGHINSVRSVAFSSDGLILASGSDDETIKLWDVK 1482 Score = 79.3 bits (194), Expect = 6e-15 Identities = 37/106 (34%), Positives = 60/106 (56%) Frame = -2 Query: 439 VYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDST 260 V FSPDG+ A+ V+ W TGK + +GH + V + +S D ++L SGS D T Sbjct: 870 VAFSPDGKLFATGDSGGIVRFWEAATGKELLTCKGHNSWVNSVGFSQDGKMLASGSDDQT 929 Query: 259 LKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 +++WDI + + + GH V +V +SP+ + SG D+ ++LW Sbjct: 930 VRLWDISSGQCLKTFKGHTSRVRSVVFSPNSLMLASGSSDQTVRLW 975 Score = 45.4 bits (106), Expect = 1e-04 Identities = 27/66 (40%), Positives = 38/66 (57%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SGSDD T+ LW + S + + GH V V FS DG LAS S D+++KLW+ TG+ Sbjct: 1427 SGSDDQTVRLWNIS-SGECLYTLHGHINSVRSVAFSSDGLILASGSDDETIKLWDVKTGE 1485 Query: 355 FVTAFR 338 + + Sbjct: 1486 CIKTLK 1491 Score = 43.1 bits (100), Expect = 5e-04 Identities = 20/76 (26%), Positives = 37/76 (48%) Frame = -2 Query: 349 TAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPD 170 + F + V +++S D +L +G ++ W+ K GH V +V +S D Sbjct: 858 SVFTKILGSVLTVAFSPDGKLFATGDSGGIVRFWEAATGKELLTCKGHNSWVNSVGFSQD 917 Query: 169 GEKVVSGGKDRALKLW 122 G+ + SG D+ ++LW Sbjct: 918 GKMLASGSDDQTVRLW 933
>Y2800_ANASP (Q8YTC2) Hypothetical WD-repeat protein alr2800| Length = 1258 Score = 105 bits (263), Expect = 6e-23 Identities = 54/138 (39%), Positives = 85/138 (61%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 S + D T+ LW+ + K + + H V V FS DGQ LAS S D+++K+WN TG+ Sbjct: 785 SSAADHTIKLWDVSQGKCLRT-LKSHTGWVRSVAFSADGQTLASGSGDRTIKIWNYHTGE 843 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 + + GH VY I++S DS++L+SGS D T+K+WD + + L GH +EV +V +S Sbjct: 844 CLKTYIGHTNSVYSIAYSPDSKILVSGSGDRTIKLWDCQTHICIKTLHGHTNEVCSVAFS 903 Query: 175 PDGEKVVSGGKDRALKLW 122 PDG+ + D++++LW Sbjct: 904 PDGQTLACVSLDQSVRLW 921 Score = 103 bits (257), Expect = 3e-22 Identities = 55/138 (39%), Positives = 80/138 (57%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SGS D T+ LW+ K + GH V V FSPDGQ LA S D+SV+LWN TG+ Sbjct: 869 SGSGDRTIKLWDCQTHICIKT-LHGHTNEVCSVAFSPDGQTLACVSLDQSVRLWNCRTGQ 927 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 + A+ G+ +++S D ++L SGS D T+K+WD + K L GH D +Y + +S Sbjct: 928 CLKAWYGNTDWALPVAFSPDRQILASGSNDKTVKLWDWQTGKYISSLEGHTDFIYGIAFS 987 Query: 175 PDGEKVVSGGKDRALKLW 122 PD + + S D +++LW Sbjct: 988 PDSQTLASASTDSSVRLW 1005 Score = 101 bits (252), Expect = 1e-21 Identities = 53/138 (38%), Positives = 80/138 (57%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 S S D T+ LW+ + +TGH V V FSPDG LAS++ D ++KLW+ GK Sbjct: 743 SASGDKTIKLWDIQDGTCLQT-LTGHTDWVRCVAFSPDGNTLASSAADHTIKLWDVSQGK 801 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 + + H V +++SAD + L SGS D T+K+W+ + + GH + VY++ +S Sbjct: 802 CLRTLKSHTGWVRSVAFSADGQTLASGSGDRTIKIWNYHTGECLKTYIGHTNSVYSIAYS 861 Query: 175 PDGEKVVSGGKDRALKLW 122 PD + +VSG DR +KLW Sbjct: 862 PDSKILVSGSGDRTIKLW 879 Score = 100 bits (249), Expect = 3e-21 Identities = 50/138 (36%), Positives = 80/138 (57%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SGS+D T+ LW+ K + + GH + + FSPD Q LASAS D SV+LWN TG+ Sbjct: 953 SGSNDKTVKLWDWQTGKYISS-LEGHTDFIYGIAFSPDSQTLASASTDSSVRLWNISTGQ 1011 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 H VY + + +++ +GS D T+K+W+I + + L H+D++ + WS Sbjct: 1012 CFQILLEHTDWVYAVVFHPQGKIIATGSADCTVKLWNISTGQCLKTLSEHSDKILGMAWS 1071 Query: 175 PDGEKVVSGGKDRALKLW 122 PDG+ + S D++++LW Sbjct: 1072 PDGQLLASASADQSVRLW 1089 Score = 96.7 bits (239), Expect = 4e-20 Identities = 50/138 (36%), Positives = 82/138 (59%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 +GS D T+ LW + + K ++ H + + +SPDGQ LASAS D+SV+LW+ TG+ Sbjct: 1037 TGSADCTVKLWNISTGQCLKT-LSEHSDKILGMAWSPDGQLLASASADQSVRLWDCCTGR 1095 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 V RGH VY +S + ++ + S D T+K+WD + K + L GH + V+ + +S Sbjct: 1096 CVGILRGHSNRVYSAIFSPNGEIIATCSTDQTVKIWDWQQGKCLKTLTGHTNWVFDIAFS 1155 Query: 175 PDGEKVVSGGKDRALKLW 122 PDG+ + S D+ +++W Sbjct: 1156 PDGKILASASHDQTVRIW 1173 Score = 95.9 bits (237), Expect = 6e-20 Identities = 48/106 (45%), Positives = 69/106 (65%) Frame = -2 Query: 439 VYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDST 260 V FSPD Q LAS S DK+VKLW+ TGK++++ GH +Y I++S DS+ L S S DS+ Sbjct: 942 VAFSPDRQILASGSNDKTVKLWDWQTGKYISSLEGHTDFIYGIAFSPDSQTLASASTDSS 1001 Query: 259 LKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 +++W+I + Q L H D VYAV + P G+ + +G D +KLW Sbjct: 1002 VRLWNISTGQCFQILLEHTDWVYAVVFHPQGKIIATGSADCTVKLW 1047 Score = 95.5 bits (236), Expect = 8e-20 Identities = 47/114 (41%), Positives = 63/114 (55%) Frame = -2 Query: 463 GHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLL 284 GH V V FSPDG+ LAS D++VKLW+ G + GH +V+ +++ D L Sbjct: 682 GHSNWVRFVVFSPDGEILASCGADENVKLWSVRDGVCIKTLTGHEHEVFSVAFHPDGETL 741 Query: 283 LSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 S S D T+K+WDI+ Q L GH D V V +SPDG + S D +KLW Sbjct: 742 ASASGDKTIKLWDIQDGTCLQTLTGHTDWVRCVAFSPDGNTLASSAADHTIKLW 795 Score = 95.1 bits (235), Expect = 1e-19 Identities = 48/138 (34%), Positives = 79/138 (57%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 S S D ++ LW+ + + + GH V FSP+G+ +A+ S D++VK+W+ GK Sbjct: 1079 SASADQSVRLWD-CCTGRCVGILRGHSNRVYSAIFSPNGEIIATCSTDQTVKIWDWQQGK 1137 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 + GH V+ I++S D ++L S S D T+++WD+ K GH V +V +S Sbjct: 1138 CLKTLTGHTNWVFDIAFSPDGKILASASHDQTVRIWDVNTGKCHHICIGHTHLVSSVAFS 1197 Query: 175 PDGEKVVSGGKDRALKLW 122 PDGE V SG +D+ +++W Sbjct: 1198 PDGEVVASGSQDQTVRIW 1215 Score = 91.3 bits (225), Expect = 2e-18 Identities = 46/116 (39%), Positives = 67/116 (57%) Frame = -2 Query: 469 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 290 +TGH+ V V F PDG+ LASAS DK++KLW+ G + GH V +++S D Sbjct: 722 LTGHEHEVFSVAFHPDGETLASASGDKTIKLWDIQDGTCLQTLTGHTDWVRCVAFSPDGN 781 Query: 289 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 L S + D T+K+WD+ K + L H V +V +S DG+ + SG DR +K+W Sbjct: 782 TLASSAADHTIKLWDVSQGKCLRTLKSHTGWVRSVAFSADGQTLASGSGDRTIKIW 837 Score = 81.6 bits (200), Expect = 1e-15 Identities = 45/138 (32%), Positives = 74/138 (53%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 S S D ++ LW + Q + H V V F P G+ +A+ S D +VKLWN TG+ Sbjct: 995 SASTDSSVRLWNISTG-QCFQILLEHTDWVYAVVFHPQGKIIATGSADCTVKLWNISTGQ 1053 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 + H + ++WS D +LL S S D ++++WD + L GH++ VY+ +S Sbjct: 1054 CLKTLSEHSDKILGMAWSPDGQLLASASADQSVRLWDCCTGRCVGILRGHSNRVYSAIFS 1113 Query: 175 PDGEKVVSGGKDRALKLW 122 P+GE + + D+ +K+W Sbjct: 1114 PNGEIIATCSTDQTVKIW 1131 Score = 78.6 bits (192), Expect = 1e-14 Identities = 39/104 (37%), Positives = 58/104 (55%) Frame = -2 Query: 433 FSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLK 254 FSP+GQ LA+ D V++W +GK + RGH V + +S D +L S D +K Sbjct: 650 FSPEGQLLATCDTDCHVRVWEVKSGKLLLICRGHSNWVRFVVFSPDGEILASCGADENVK 709 Query: 253 VWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 +W +R + L GH EV++V + PDGE + S D+ +KLW Sbjct: 710 LWSVRDGVCIKTLTGHEHEVFSVAFHPDGETLASASGDKTIKLW 753 Score = 71.2 bits (173), Expect = 2e-12 Identities = 39/105 (37%), Positives = 63/105 (60%) Frame = -2 Query: 529 SDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFV 350 S D T+ +W+ K K +TGH V + FSPDG+ LASAS D++V++W+ TGK Sbjct: 1123 STDQTVKIWDWQQGKCLKT-LTGHTNWVFDIAFSPDGKILASASHDQTVRIWDVNTGKCH 1181 Query: 349 TAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDL 215 GH V +++S D ++ SGS+D T+++W+++ + Q L Sbjct: 1182 HICIGHTHLVSSVAFSPDGEVVASGSQDQTVRIWNVKTGECLQIL 1226 Score = 48.5 bits (114), Expect = 1e-05 Identities = 24/74 (32%), Positives = 43/74 (58%) Frame = -2 Query: 343 FRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGE 164 F + ++ ++S + +LL + D ++VW++++ KL GH++ V V +SPDGE Sbjct: 638 FTETLGNILSAAFSPEGQLLATCDTDCHVRVWEVKSGKLLLICRGHSNWVRFVVFSPDGE 697 Query: 163 KVVSGGKDRALKLW 122 + S G D +KLW Sbjct: 698 ILASCGADENVKLW 711 Score = 45.8 bits (107), Expect = 7e-05 Identities = 25/66 (37%), Positives = 39/66 (59%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 S S D T+ +W+ K + GH +V+ V FSPDG+ +AS S D++V++WN TG+ Sbjct: 1163 SASHDQTVRIWDVNTGKCHHICI-GHTHLVSSVAFSPDGEVVASGSQDQTVRIWNVKTGE 1221 Query: 355 FVTAFR 338 + R Sbjct: 1222 CLQILR 1227
>PKWA_THECU (P49695) Probable serine/threonine-protein kinase pkwA (EC| 2.7.11.1) Length = 742 Score = 100 bits (250), Expect = 2e-21 Identities = 52/138 (37%), Positives = 80/138 (57%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SGSDD T+ LW+ +++ +A GH V + FSPDG +AS S D + +LWN TG Sbjct: 518 SGSDDATVRLWDVAAAEE-RAVFEGHTHYVLDIAFSPDGSMVASGSRDGTARLWNVATGT 576 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 +GH VY +++S D ++ SGS+D T+++WD+ K + L A+ V ++ +S Sbjct: 577 EHAVLKGHTDYVYAVAFSPDGSMVASGSRDGTIRLWDVATGKERDVLQAPAENVVSLAFS 636 Query: 175 PDGEKVVSGGKDRALKLW 122 PDG +V G D + LW Sbjct: 637 PDGSMLVH-GSDSTVHLW 653 Score = 99.4 bits (246), Expect = 6e-21 Identities = 53/137 (38%), Positives = 74/137 (54%) Frame = -2 Query: 532 GSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKF 353 GS D + +W+ S + GH V V FSPDG LAS S D +V+LW+ + Sbjct: 477 GSGDKLIHVWD-VASGDELHTLEGHTDWVRAVAFSPDGALLASGSDDATVRLWDVAAAEE 535 Query: 352 VTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSP 173 F GH V I++S D ++ SGS+D T ++W++ L GH D VYAV +SP Sbjct: 536 RAVFEGHTHYVLDIAFSPDGSMVASGSRDGTARLWNVATGTEHAVLKGHTDYVYAVAFSP 595 Query: 172 DGEKVVSGGKDRALKLW 122 DG V SG +D ++LW Sbjct: 596 DGSMVASGSRDGTIRLW 612 Score = 92.0 bits (227), Expect = 9e-19 Identities = 48/138 (34%), Positives = 78/138 (56%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SGS D T+ LW+ K+ + VV+ + FSPDG L S D +V LW+ +G+ Sbjct: 602 SGSRDGTIRLWDVATGKERDVLQAPAENVVS-LAFSPDGSMLVHGS-DSTVHLWDVASGE 659 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 + F GH V +++S D LL SGS D T+++WD+ A++ L GH + V++V + Sbjct: 660 ALHTFEGHTDWVRAVAFSPDGALLASGSDDRTIRLWDVAAQEEHTTLEGHTEPVHSVAFH 719 Query: 175 PDGEKVVSGGKDRALKLW 122 P+G + S +D +++W Sbjct: 720 PEGTTLASASEDGTIRIW 737 Score = 83.6 bits (205), Expect = 3e-16 Identities = 44/127 (34%), Positives = 67/127 (52%) Frame = -2 Query: 502 EPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVAD 323 +P +P+ T + V V FSP G LA S DK + +W+ +G + GH Sbjct: 446 DPHELNEPRILTTDREAVA--VAFSPGGSLLAGGSGDKLIHVWDVASGDELHTLEGHTDW 503 Query: 322 VYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGK 143 V +++S D LL SGS D+T+++WD+ A + + GH V + +SPDG V SG + Sbjct: 504 VRAVAFSPDGALLASGSDDATVRLWDVAAAEERAVFEGHTHYVLDIAFSPDGSMVASGSR 563 Query: 142 DRALKLW 122 D +LW Sbjct: 564 DGTARLW 570 Score = 62.8 bits (151), Expect = 6e-10 Identities = 32/94 (34%), Positives = 50/94 (53%) Frame = -2 Query: 523 DFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTA 344 D T+ LW+ S + GH V V FSPDG LAS S D++++LW+ + T Sbjct: 647 DSTVHLWD-VASGEALHTFEGHTDWVRAVAFSPDGALLASGSDDRTIRLWDVAAQEEHTT 705 Query: 343 FRGHVADVYQISWSADSRLLLSGSKDSTLKVWDI 242 GH V+ +++ + L S S+D T+++W I Sbjct: 706 LEGHTEPVHSVAFHPEGTTLASASEDGTIRIWPI 739
>GBLP_DROME (O18640) Guanine nucleotide-binding protein beta subunit-like| protein (Receptor of activated protein kinase C homolog) Length = 318 Score = 97.8 bits (242), Expect = 2e-20 Identities = 53/146 (36%), Positives = 83/146 (56%), Gaps = 8/146 (5%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQ-----PKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWN 371 S S D T+ +W+ T + P+ R+ GH ++ V S DG + S S+D++++LW+ Sbjct: 33 SASRDKTLIVWKLTRDEDTNYGYPQKRLYGHSHFISDVVLSSDGNYALSGSWDQTLRLWD 92 Query: 370 GITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRAR-KLKQDLPGHADEV 194 GK F GH DV +++SAD+R ++SGS+D T+K+W+ A K GH D V Sbjct: 93 LAAGKTTRRFEGHTKDVLSVAFSADNRQIVSGSRDKTIKLWNTLAECKFTIQEDGHTDWV 152 Query: 193 YAVDWSPDGEK--VVSGGKDRALKLW 122 V +SP+ +VS G DR +K+W Sbjct: 153 SCVRFSPNHSNPIIVSCGWDRTVKVW 178 Score = 57.4 bits (137), Expect = 2e-08 Identities = 40/124 (32%), Positives = 59/124 (47%), Gaps = 2/124 (1%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPD--GQWLASASFDKSVKLWNGIT 362 SGS D T+ LW + + GH V+ V FSP+ + S +D++VK+WN Sbjct: 123 SGSRDKTIKLWNTLAECKFTIQEDGHTDWVSCVRFSPNHSNPIIVSCGWDRTVKVWNLAN 182 Query: 361 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 182 K GH + ++ S D L SG KDS +WD+ K L H D + A+ Sbjct: 183 CKLKNNHHGHNGYLNTVTVSPDGSLCTSGGKDSKALLWDLNDGKNLYTLE-HNDIINALC 241 Query: 181 WSPD 170 +SP+ Sbjct: 242 FSPN 245 Score = 50.8 bits (120), Expect = 2e-06 Identities = 33/107 (30%), Positives = 50/107 (46%), Gaps = 9/107 (8%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SG D LW+ K H ++N + FSP+ WL A + S+K+W+ K Sbjct: 210 SGGKDSKALLWDLNDGKN--LYTLEHNDIINALCFSPNRYWLCVA-YGPSIKIWDLACKK 266 Query: 355 FVTAFRGHV------ADVYQ---ISWSADSRLLLSGSKDSTLKVWDI 242 V R V AD Q ++WS D + L +G D+T++VW + Sbjct: 267 TVEELRPEVVSPTSKADQPQCLSLAWSTDGQTLFAGYSDNTIRVWQV 313 Score = 37.7 bits (86), Expect = 0.020 Identities = 27/79 (34%), Positives = 39/79 (49%), Gaps = 7/79 (8%) Frame = -2 Query: 337 GHVADVYQISWSA-DSRLLLSGSKDSTLKVW------DIRARKLKQDLPGHADEVYAVDW 179 GH V QI+ + D ++S S+D TL VW D ++ L GH+ + V Sbjct: 13 GHNGWVTQIATNPKDPDTIISASRDKTLIVWKLTRDEDTNYGYPQKRLYGHSHFISDVVL 72 Query: 178 SPDGEKVVSGGKDRALKLW 122 S DG +SG D+ L+LW Sbjct: 73 SSDGNYALSGSWDQTLRLW 91
>GBLP_NEUCR (Q01369) Guanine nucleotide-binding protein beta subunit-like| protein (Cross-pathway control WD-repeat protein cpc-2) Length = 316 Score = 97.4 bits (241), Expect = 2e-20 Identities = 55/150 (36%), Positives = 86/150 (57%), Gaps = 7/150 (4%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQ----PKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNG 368 SGS D ++ +W T + PK R+ GH +V+ S DG + SAS+DK+++LW Sbjct: 33 SGSRDKSLIIWNLTRDETSYGYPKRRLHGHSHIVSDCVISSDGAYALSASWDKTLRLWEL 92 Query: 367 ITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD-IRARKLKQDLPGHADEVY 191 TG F GH DV +S+SAD+R ++SGS+D T+K+W+ + K GH + V Sbjct: 93 STGTTTRRFVGHTNDVLSVSFSADNRQIVSGSRDRTIKLWNTLGDCKFTITEKGHTEWVS 152 Query: 190 AVDWSPDGEK--VVSGGKDRALKLWMN*AC 107 V +SP+ + +VS G D+ +K+W +C Sbjct: 153 CVRFSPNPQNPVIVSSGWDKLVKVWELSSC 182 Score = 63.2 bits (152), Expect = 5e-10 Identities = 42/124 (33%), Positives = 63/124 (50%), Gaps = 2/124 (1%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQ--WLASASFDKSVKLWNGIT 362 SGS D T+ LW + GH + V+ V FSP+ Q + S+ +DK VK+W + Sbjct: 122 SGSRDRTIKLWNTLGDCKFTITEKGHTEWVSCVRFSPNPQNPVIVSSGWDKLVKVWELSS 181 Query: 361 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 182 K T GH + ++ S D L SG KD T +WD+ K L + DE++A+ Sbjct: 182 CKLQTDHIGHTGYINAVTISPDGSLCASGGKDGTTMLWDLNESKHLYSLNAN-DEIHALV 240 Query: 181 WSPD 170 +SP+ Sbjct: 241 FSPN 244 Score = 38.5 bits (88), Expect = 0.012 Identities = 25/78 (32%), Positives = 41/78 (52%), Gaps = 6/78 (7%) Frame = -2 Query: 337 GHVADVYQISWSADS-RLLLSGSKDSTLKVWDIRARKL-----KQDLPGHADEVYAVDWS 176 GH V ++ S ++ +LLSGS+D +L +W++ + K+ L GH+ V S Sbjct: 13 GHNGWVTSLATSLENPNMLLSGSRDKSLIIWNLTRDETSYGYPKRRLHGHSHIVSDCVIS 72 Query: 175 PDGEKVVSGGKDRALKLW 122 DG +S D+ L+LW Sbjct: 73 SDGAYALSASWDKTLRLW 90 Score = 37.4 bits (85), Expect = 0.027 Identities = 26/110 (23%), Positives = 51/110 (46%), Gaps = 9/110 (8%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASAS--------FDKSVK 380 SG D T LW+ SK + + ++ + FSP+ WL +A+ +K K Sbjct: 209 SGGKDGTTMLWDLNESKHLYSLNANDE--IHALVFSPNRYWLCAATSSSIIIFDLEKKSK 266 Query: 379 LWNGITGKFVT-AFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRAR 233 + + + +F + + ++WSAD + L +G D+ ++ W + +R Sbjct: 267 V-DELKPEFQNIGKKSREPECVSLAWSADGQTLFAGYTDNIIRAWGVMSR 315
>WD51A_MOUSE (Q8JZX3) WD-repeat protein 51A| Length = 405 Score = 95.9 bits (237), Expect = 6e-20 Identities = 53/139 (38%), Positives = 75/139 (53%), Gaps = 1/139 (0%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKA-RMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITG 359 SGS D T+ +W + Q +A R TGH+ V V FSP G LAS S DK+V++W Sbjct: 36 SGSMDSTLMIWH--MKPQSRAYRFTGHKDAVTCVNFSPSGHLLASGSRDKTVRIWVPNVK 93 Query: 358 KFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDW 179 T FR H A V + + +D + L++ S D T+KVW ++ L H + V + Sbjct: 94 GESTVFRAHTATVRSVHFCSDGQSLVTASDDKTVKVWSTHRQRFLFSLTQHINWVRCAKF 153 Query: 178 SPDGEKVVSGGKDRALKLW 122 SPDG +VS D+ +KLW Sbjct: 154 SPDGRLIVSASDDKTVKLW 172 Score = 87.4 bits (215), Expect = 2e-17 Identities = 48/138 (34%), Positives = 72/138 (52%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SGS D T+ +W P + K H V V+F DGQ L +AS DK+VK+W+ + Sbjct: 78 SGSRDKTVRIWVPNV-KGESTVFRAHTATVRSVHFCSDGQSLVTASDDKTVKVWSTHRQR 136 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 F+ + H+ V +S D RL++S S D T+K+WD +R+ H V VD+ Sbjct: 137 FLFSLTQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKTSRECIHSYCEHGGFVTYVDFH 196 Query: 175 PDGEKVVSGGKDRALKLW 122 P G + + G D +K+W Sbjct: 197 PSGTCIAAAGMDNTVKVW 214 Score = 81.6 bits (200), Expect = 1e-15 Identities = 47/138 (34%), Positives = 71/138 (51%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 S SDD T+ LW+ T S++ H V +V F P G +A+A D +VK+W+ T + Sbjct: 162 SASDDKTVKLWDKT-SRECIHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDARTHR 220 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 + ++ H A V +S+ L++ S DSTLK+ D+ +L L GH V +S Sbjct: 221 LLQHYQLHSAAVNALSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFS 280 Query: 175 PDGEKVVSGGKDRALKLW 122 GE SGG D + +W Sbjct: 281 RTGEYFASGGSDEQVMVW 298 Score = 74.7 bits (182), Expect = 2e-13 Identities = 42/137 (30%), Positives = 71/137 (51%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 + SDD T+ +W T ++ +T H V FSPDG+ + SAS DK+VKLW+ + + Sbjct: 120 TASDDKTVKVWS-THRQRFLFSLTQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKTSRE 178 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 + ++ H V + + + + D+T+KVWD R +L Q H+ V A+ + Sbjct: 179 CIHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDARTHRLLQHYQLHSAAVNALSFH 238 Query: 175 PDGEKVVSGGKDRALKL 125 P G +++ D LK+ Sbjct: 239 PSGNYLITASSDSTLKI 255 Score = 63.9 bits (154), Expect = 3e-10 Identities = 34/114 (29%), Positives = 57/114 (50%) Frame = -2 Query: 463 GHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLL 284 GH+ V V FS + + LAS S D ++ +W+ F GH V +++S LL Sbjct: 17 GHRDAVTCVDFSLNTKHLASGSMDSTLMIWHMKPQSRAYRFTGHKDAVTCVNFSPSGHLL 76 Query: 283 LSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 SGS+D T+++W + H V +V + DG+ +V+ D+ +K+W Sbjct: 77 ASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSLVTASDDKTVKVW 130 Score = 60.1 bits (144), Expect = 4e-09 Identities = 26/75 (34%), Positives = 45/75 (60%) Frame = -2 Query: 343 FRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGE 164 F+GH V + +S +++ L SGS DSTL +W ++ + GH D V V++SP G Sbjct: 15 FKGHRDAVTCVDFSLNTKHLASGSMDSTLMIWHMKPQSRAYRFTGHKDAVTCVNFSPSGH 74 Query: 163 KVVSGGKDRALKLWM 119 + SG +D+ +++W+ Sbjct: 75 LLASGSRDKTVRIWV 89 Score = 30.0 bits (66), Expect = 4.3 Identities = 13/36 (36%), Positives = 20/36 (55%) Frame = -2 Query: 229 LKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 L++ GH D V VD+S + + + SG D L +W Sbjct: 11 LERHFKGHRDAVTCVDFSLNTKHLASGSMDSTLMIW 46
>KTNB1_BRARE (Q7ZUV2) Katanin p80 WD40-containing subunit B1 homolog| Length = 694 Score = 93.2 bits (230), Expect = 4e-19 Identities = 52/132 (39%), Positives = 74/132 (56%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SGS D + LW+ K R GH + V + FSPDG+WLASAS D +VKLW+ I GK Sbjct: 122 SGSVDSNIKLWDVR-RKGCVFRYKGHTQAVRCLAFSPDGKWLASASDDSTVKLWDLIAGK 180 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 +T F H + V + + + LL SGS D T+K+WD+ + G V +V ++ Sbjct: 181 MITEFTSHTSAVNVVQFHPNEYLLASGSADRTVKLWDLEKFNMIGSSEGETGVVRSVLFN 240 Query: 175 PDGEKVVSGGKD 140 PDG + SG ++ Sbjct: 241 PDGSCLYSGSEN 252 Score = 87.0 bits (214), Expect = 3e-17 Identities = 47/138 (34%), Positives = 77/138 (55%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 +GS ++ LW+ +K + M GH+ ++ + F P G++LAS S D ++KLW+ Sbjct: 80 AGSLSGSLRLWDLEAAKILRTLM-GHKASISSLDFHPMGEYLASGSVDSNIKLWDVRRKG 138 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 V ++GH V +++S D + L S S DST+K+WD+ A K+ + H V V + Sbjct: 139 CVFRYKGHTQAVRCLAFSPDGKWLASASDDSTVKLWDLIAGKMITEFTSHTSAVNVVQFH 198 Query: 175 PDGEKVVSGGKDRALKLW 122 P+ + SG DR +KLW Sbjct: 199 PNEYLLASGSADRTVKLW 216 Score = 74.3 bits (181), Expect = 2e-13 Identities = 42/140 (30%), Positives = 68/140 (48%), Gaps = 2/140 (1%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARM--TGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 362 +G +D + +W +SK P M TGH V + F+ + + + S S++LW+ Sbjct: 38 TGGEDCRVNIW--AVSK-PNCIMSLTGHTSAVGCIQFNSSEERVVAGSLSGSLRLWDLEA 94 Query: 361 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 182 K + GH A + + + L SGS DS +K+WD+R + GH V + Sbjct: 95 AKILRTLMGHKASISSLDFHPMGEYLASGSVDSNIKLWDVRRKGCVFRYKGHTQAVRCLA 154 Query: 181 WSPDGEKVVSGGKDRALKLW 122 +SPDG+ + S D +KLW Sbjct: 155 FSPDGKWLASASDDSTVKLW 174 Score = 64.7 bits (156), Expect = 2e-10 Identities = 36/132 (27%), Positives = 64/132 (48%), Gaps = 1/132 (0%) Frame = -2 Query: 514 MFLWEPTISKQPKARMTGHQKVVNHVYFSPD-GQWLASASFDKSVKLWNGITGKFVTAFR 338 M L TI+ + H V+ + G+ LA+ D V +W + + Sbjct: 1 MALTNTTITSWKLQEIVAHSSNVSSLVLGKSSGRLLATGGEDCRVNIWAVSKPNCIMSLT 60 Query: 337 GHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKV 158 GH + V I +++ +++GS +L++WD+ A K+ + L GH + ++D+ P GE + Sbjct: 61 GHTSAVGCIQFNSSEERVVAGSLSGSLRLWDLEAAKILRTLMGHKASISSLDFHPMGEYL 120 Query: 157 VSGGKDRALKLW 122 SG D +KLW Sbjct: 121 ASGSVDSNIKLW 132 Score = 53.9 bits (128), Expect = 3e-07 Identities = 40/133 (30%), Positives = 61/133 (45%), Gaps = 2/133 (1%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 S SDD T+ LW+ I+ + T H VN V F P+ LAS S D++VKLW+ Sbjct: 164 SASDDSTVKLWD-LIAGKMITEFTSHTSAVNVVQFHPNEYLLASGSADRTVKLWDLEKFN 222 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKV--WDIRARKLKQDLPGHADEVYAVD 182 + + G V + ++ D L SGS ++TL+V W+ P +V V Sbjct: 223 MIGSSEGETGVVRSVLFNPDGSCLYSGS-ENTLRVYGWE----------PDRCFDVVHVG 271 Query: 181 WSPDGEKVVSGGK 143 W + +S + Sbjct: 272 WGKVSDLAISNNQ 284
>GBLP_DICDI (P46800) Guanine nucleotide-binding protein beta subunit-like| protein Length = 329 Score = 92.4 bits (228), Expect = 7e-19 Identities = 54/146 (36%), Positives = 84/146 (57%), Gaps = 8/146 (5%) Frame = -2 Query: 535 SGSDDFTMFLWE--PTISKQP-KAR--MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWN 371 S S D T+ +W+ PT + P KA + GH V V S DGQ+ S S+D +++LW+ Sbjct: 39 SSSRDKTVMVWQLTPTDATSPGKAHRSLKGHSHFVQDVVISHDGQFALSGSWDNTLRLWD 98 Query: 370 GITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPG---HAD 200 G F+GH DV +++S+D+R ++SGS+D+T+KVW+ + K L G H D Sbjct: 99 ITKGVSTRLFKGHTQDVMSVAFSSDNRQIISGSRDATIKVWNTLG-ECKFTLEGPEAHQD 157 Query: 199 EVYAVDWSPDGEKVVSGGKDRALKLW 122 V + +SP+ +VSG D +K+W Sbjct: 158 WVSCIRFSPNTPTIVSGSWDNKVKIW 183 Score = 49.3 bits (116), Expect = 7e-06 Identities = 39/141 (27%), Positives = 67/141 (47%), Gaps = 3/141 (2%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTG---HQKVVNHVYFSPDGQWLASASFDKSVKLWNGI 365 SGS D T+ +W + K + G HQ V+ + FSP+ + S S+D VK+W+ Sbjct: 129 SGSRDATIKVWNTL--GECKFTLEGPEAHQDWVSCIRFSPNTPTIVSGSWDNKVKIWDIK 186 Query: 364 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAV 185 + K H V ++ S D L SG KD+ +W++ + K L + + A+ Sbjct: 187 SFKCNHTLTDHTGYVNTVTISPDGSLCASGGKDTFACLWELSSGKPLYKLEAR-NTINAL 245 Query: 184 DWSPDGEKVVSGGKDRALKLW 122 +SP+ + +S D + +W Sbjct: 246 AFSPN-KYWLSAATDDKIIIW 265 Score = 42.0 bits (97), Expect = 0.001 Identities = 36/155 (23%), Positives = 63/155 (40%), Gaps = 17/155 (10%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SGS D + +W+ S + +T H VN V SPDG AS D LW +GK Sbjct: 173 SGSWDNKVKIWDIK-SFKCNHTLTDHTGYVNTVTISPDGSLCASGGKDTFACLWELSSGK 231 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRAR-----------------KL 227 ++ + + ++ LS + D + +WD+ + K Sbjct: 232 --PLYKLEARNTINALAFSPNKYWLSAATDDKIIIWDLLTKQVLAEIVPEVKEQAFDSKK 289 Query: 226 KQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 K++ A ++ WS DG + +G D ++++ Sbjct: 290 KKESKPKAPACLSLAWSADGSVLYAGYNDGLIRVY 324 Score = 39.3 bits (90), Expect = 0.007 Identities = 26/79 (32%), Positives = 39/79 (49%), Gaps = 7/79 (8%) Frame = -2 Query: 337 GHVADVYQISWSADSR-LLLSGSKDSTLKVWDIRAR------KLKQDLPGHADEVYAVDW 179 GH V I+ S ++ ++S S+D T+ VW + K + L GH+ V V Sbjct: 19 GHNGFVTSIAVSPENPDTIISSSRDKTVMVWQLTPTDATSPGKAHRSLKGHSHFVQDVVI 78 Query: 178 SPDGEKVVSGGKDRALKLW 122 S DG+ +SG D L+LW Sbjct: 79 SHDGQFALSGSWDNTLRLW 97
>Y143_SYNY3 (P74442) Hypothetical WD-repeat protein slr0143| Length = 1191 Score = 92.4 bits (228), Expect = 7e-19 Identities = 45/116 (38%), Positives = 69/116 (59%) Frame = -2 Query: 469 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 290 +TGH+ V V S +ASAS D +V LW G+F+ F GH +Y++ +S + + Sbjct: 556 LTGHRDGVTSVAISSHKNLIASASRDGTVHLWTP-QGEFLREFTGHTGSIYRVDFSPNGK 614 Query: 289 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 + + +D T+K+WD+ L Q L GH D VY+V +SPDGE + S +DR ++LW Sbjct: 615 IFATAGQDQTVKIWDLDG-NLLQTLKGHQDSVYSVSFSPDGEILASTSRDRTVRLW 669 Score = 79.7 bits (195), Expect = 5e-15 Identities = 44/139 (31%), Positives = 73/139 (52%), Gaps = 1/139 (0%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 + D T+ +W+ + + GHQ V V FSPDG+ LAS S D++V+LW+ +GK Sbjct: 618 TAGQDQTVKIWD--LDGNLLQTLKGHQDSVYSVSFSPDGEILASTSRDRTVRLWHWRSGK 675 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQ-DLPGHADEVYAVDW 179 + GH V +S D + L+S +D +++WD+ ++Q LP A + V+W Sbjct: 676 TLAVLGGHTKSVDDAQFSPDGQTLVSVCRDGQIRLWDLDGNLIRQFGLPEVA--FFGVNW 733 Query: 178 SPDGEKVVSGGKDRALKLW 122 P+G + D ++LW Sbjct: 734 HPNGNLLAVAADDGTVRLW 752 Score = 67.8 bits (164), Expect = 2e-11 Identities = 42/138 (30%), Positives = 70/138 (50%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 S S D T+ LW K A + GH K V+ FSPDGQ L S D ++LW+ + G Sbjct: 659 STSRDRTVRLWHWRSGKT-LAVLGGHTKSVDDAQFSPDGQTLVSVCRDGQIRLWD-LDGN 716 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 + F + ++W + LL + D T+++W + ++K L GH + V V ++ Sbjct: 717 LIRQFGLPEVAFFGVNWHPNGNLLAVAADDGTVRLWTPQG-EIKATLSGHDEFVTRVVFT 775 Query: 175 PDGEKVVSGGKDRALKLW 122 PDG+++ S + ++ W Sbjct: 776 PDGKQLFSSSSNGSVIHW 793 Score = 62.8 bits (151), Expect = 6e-10 Identities = 32/96 (33%), Positives = 61/96 (63%) Frame = -2 Query: 529 SDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFV 350 +DD T+ LW P + KA ++GH + V V F+PDG+ L S+S + SV W+ +GK + Sbjct: 744 ADDGTVRLWTP--QGEIKATLSGHDEFVTRVVFTPDGKQLFSSSSNGSVIHWS-TSGKML 800 Query: 349 TAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDI 242 ++G+ ++ ++ +++ LL G++++ +KVWD+ Sbjct: 801 KKYQGYPEAIFGLALASNGALLAIGAENNLVKVWDM 836 Score = 49.3 bits (116), Expect = 7e-06 Identities = 24/116 (20%), Positives = 63/116 (54%) Frame = -2 Query: 469 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 290 + H +N + +SP+G++L SA + + K+W+ + G+ + + + QI+ S DS+ Sbjct: 1034 IVAHGDRLNQLQYSPNGKYLLSAGREGTAKIWS-VEGQLLHTLKSDPLPIDQIAISPDSQ 1092 Query: 289 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 + + + D +++WD + L+ + + + +D++ G+ +++ ++ L+ W Sbjct: 1093 WIATAASDGMVRLWD-QQGNLRGEFTSTSGSLLGLDFNRQGQWLLAVAQNGDLQSW 1147 Score = 43.1 bits (100), Expect = 5e-04 Identities = 25/109 (22%), Positives = 48/109 (44%) Frame = -2 Query: 448 VNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSK 269 + V P LA+ ++ LWN G + + H + Q+ +S + + LLS + Sbjct: 1000 IRSVSLHPTLPQLAAGDEQGNLTLWN-FDGTLIRSIVAHGDRLNQLQYSPNGKYLLSAGR 1058 Query: 268 DSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 + T K+W + +L L + + SPD + + + D ++LW Sbjct: 1059 EGTAKIWSVEG-QLLHTLKSDPLPIDQIAISPDSQWIATAASDGMVRLW 1106 Score = 37.7 bits (86), Expect = 0.020 Identities = 18/73 (24%), Positives = 37/73 (50%) Frame = -2 Query: 448 VNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSK 269 ++ + SPD QW+A+A+ D V+LW+ G F + + ++ + LL+ ++ Sbjct: 1082 IDQIAISPDSQWIATAASDGMVRLWDQ-QGNLRGEFTSTSGSLLGLDFNRQGQWLLAVAQ 1140 Query: 268 DSTLKVWDIRARK 230 + L+ W + K Sbjct: 1141 NGDLQSWPVTPEK 1153
>WD51A_HUMAN (Q8NBT0) WD-repeat protein 51A| Length = 407 Score = 92.0 bits (227), Expect = 9e-19 Identities = 52/139 (37%), Positives = 73/139 (52%), Gaps = 1/139 (0%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKA-RMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITG 359 SGS D + +W + Q +A R TGH+ V V FSP G LAS S DK+V++W Sbjct: 36 SGSMDSCLMVWH--MKPQSRAYRFTGHKDAVTCVNFSPSGHLLASGSRDKTVRIWVPNVK 93 Query: 358 KFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDW 179 T FR H A V + + +D + ++ S D T+KVW +K L H + V + Sbjct: 94 GESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVWATHRQKFLFSLSQHINWVRCAKF 153 Query: 178 SPDGEKVVSGGKDRALKLW 122 SPDG +VS D+ +KLW Sbjct: 154 SPDGRLIVSASDDKTVKLW 172 Score = 86.3 bits (212), Expect = 5e-17 Identities = 48/138 (34%), Positives = 70/138 (50%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SGS D T+ +W P + K H V V+F DGQ +AS DK+VK+W K Sbjct: 78 SGSRDKTVRIWVPNV-KGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVWATHRQK 136 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 F+ + H+ V +S D RL++S S D T+K+WD +R+ H V VD+ Sbjct: 137 FLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKSSRECVHSYCEHGGFVTYVDFH 196 Query: 175 PDGEKVVSGGKDRALKLW 122 P G + + G D +K+W Sbjct: 197 PSGTCIAAAGMDNTVKVW 214 Score = 79.0 bits (193), Expect = 8e-15 Identities = 46/138 (33%), Positives = 71/138 (51%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 S SDD T+ LW+ + S++ H V +V F P G +A+A D +VK+W+ T + Sbjct: 162 SASDDKTVKLWDKS-SRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHR 220 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 + ++ H A V +S+ L++ S DSTLK+ D+ +L L GH V +S Sbjct: 221 LLQHYQLHSAAVNGLSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFS 280 Query: 175 PDGEKVVSGGKDRALKLW 122 GE SGG D + +W Sbjct: 281 RTGEYFASGGSDEQVMVW 298 Score = 72.8 bits (177), Expect = 6e-13 Identities = 41/137 (29%), Positives = 71/137 (51%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 + SDD T+ +W T ++ ++ H V FSPDG+ + SAS DK+VKLW+ + + Sbjct: 120 TASDDKTVKVWA-THRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKSSRE 178 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 V ++ H V + + + + D+T+KVWD+R +L Q H+ V + + Sbjct: 179 CVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHSAAVNGLSFH 238 Query: 175 PDGEKVVSGGKDRALKL 125 P G +++ D LK+ Sbjct: 239 PSGNYLITASSDSTLKI 255 Score = 62.0 bits (149), Expect = 1e-09 Identities = 34/114 (29%), Positives = 55/114 (48%) Frame = -2 Query: 463 GHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLL 284 GH+ V V FS + + LAS S D + +W+ F GH V +++S LL Sbjct: 17 GHRDAVTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSPSGHLL 76 Query: 283 LSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 SGS+D T+++W + H V +V + DG+ V+ D+ +K+W Sbjct: 77 ASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVW 130 Score = 58.5 bits (140), Expect = 1e-08 Identities = 26/75 (34%), Positives = 44/75 (58%) Frame = -2 Query: 343 FRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGE 164 F+GH V + +S +++ L SGS DS L VW ++ + GH D V V++SP G Sbjct: 15 FKGHRDAVTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSPSGH 74 Query: 163 KVVSGGKDRALKLWM 119 + SG +D+ +++W+ Sbjct: 75 LLASGSRDKTVRIWV 89
>GBLP_HYDAT (Q25189) Guanine nucleotide-binding protein beta subunit-like| protein (Receptor of activated protein kinase C) (RACK) Length = 317 Score = 91.7 bits (226), Expect = 1e-18 Identities = 53/146 (36%), Positives = 84/146 (57%), Gaps = 8/146 (5%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQ-----PKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWN 371 S S D T+ W+ T Q PK +TGH V+ V S DGQ+ S S+DK+++LW+ Sbjct: 32 SASRDKTLIQWQLTRDDQTNYGFPKKCLTGHNHFVSDVVLSSDGQFALSCSWDKTLRLWD 91 Query: 370 GITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRAR-KLKQDLPGHADEV 194 G F GH DV +++SAD+R ++SGS+D+T+K+W+ + K H++ V Sbjct: 92 LNQGITTKQFVGHTKDVLSVAFSADNRQIVSGSRDNTIKLWNTLGQCKYTIQDESHSEWV 151 Query: 193 YAVDWSPDGEK--VVSGGKDRALKLW 122 V +SP+ + +VS G D+ +K+W Sbjct: 152 SCVRFSPNTQNPIIVSCGWDKMVKVW 177 Score = 57.0 bits (136), Expect = 3e-08 Identities = 40/124 (32%), Positives = 59/124 (47%), Gaps = 2/124 (1%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQ--WLASASFDKSVKLWNGIT 362 SGS D T+ LW + + H + V+ V FSP+ Q + S +DK VK+WN Sbjct: 122 SGSRDNTIKLWNTLGQCKYTIQDESHSEWVSCVRFSPNTQNPIIVSCGWDKMVKVWNLTN 181 Query: 361 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 182 K T GH + ++ S D L SG KD +WD+ K L G + + A+ Sbjct: 182 CKLKTNHFGHTGYLNAVTVSPDGSLCASGGKDGNAMLWDLNEGKHLYTLDG-GNVINALC 240 Query: 181 WSPD 170 +SP+ Sbjct: 241 FSPN 244 Score = 47.4 bits (111), Expect = 3e-05 Identities = 30/110 (27%), Positives = 51/110 (46%), Gaps = 12/110 (10%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWN----- 371 SG D LW+ K G+ V+N + FSP+ WL +A+ +K+W+ Sbjct: 209 SGGKDGNAMLWDLNEGKHLYTLDGGN--VINALCFSPNRYWLCAAT-GPMIKIWDLEMKS 265 Query: 370 -------GITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDI 242 G+ G + + AD ++WSAD + L +G D+ ++VW + Sbjct: 266 VVDELKPGVIG---ISTKSRAADCISLAWSADGQTLFAGYTDNLIRVWQV 312 Score = 35.4 bits (80), Expect = 0.10 Identities = 27/80 (33%), Positives = 39/80 (48%), Gaps = 7/80 (8%) Frame = -2 Query: 340 RGHVADVYQISWSADSR-LLLSGSKDSTLKVWDIRARKL------KQDLPGHADEVYAVD 182 +GH V QI+ + + L+LS S+D TL W + K+ L GH V V Sbjct: 11 KGHNGWVTQIATTPQNPDLILSASRDKTLIQWQLTRDDQTNYGFPKKCLTGHNHFVSDVV 70 Query: 181 WSPDGEKVVSGGKDRALKLW 122 S DG+ +S D+ L+LW Sbjct: 71 LSSDGQFALSCSWDKTLRLW 90
>SWD3_SCHPO (O43017) Set1 complex component swd3 (Set1C component swd3)| (COMPASS component swd3) (Complex proteins associated with set1 protein swd3) Length = 380 Score = 91.7 bits (226), Expect = 1e-18 Identities = 39/114 (34%), Positives = 68/114 (59%) Frame = -2 Query: 463 GHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLL 284 GH+K V V SP+ +W+A++S D ++K+W+ +T + GH + Q+ W+ S+ L Sbjct: 52 GHEKSVTCVSVSPNKRWIATSSSDGTIKIWSALTFRLECTLFGHYRGISQVKWATGSKYL 111 Query: 283 LSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 S S D T+++WD R + L GH + V ++D++P G +VSG D +++W Sbjct: 112 ASASDDKTIRIWDFEKRCSVRCLKGHTNYVSSIDFNPLGTLLVSGSWDETVRIW 165 Score = 72.0 bits (175), Expect = 1e-12 Identities = 37/138 (26%), Positives = 75/138 (54%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 + S D T+ +W ++ + + + GH + ++ V ++ ++LASAS DK++++W+ Sbjct: 71 TSSSDGTIKIWS-ALTFRLECTLFGHYRGISQVKWATGSKYLASASDDKTIRIWDFEKRC 129 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 V +GH V I ++ LL+SGS D T+++W+++ + LP H++ + +V S Sbjct: 130 SVRCLKGHTNYVSSIDFNPLGTLLVSGSWDETVRIWNLQDGTCLRMLPAHSEPIISVSIS 189 Query: 175 PDGEKVVSGGKDRALKLW 122 DG + D ++W Sbjct: 190 ADGTLCATASYDGMARIW 207 Score = 59.7 bits (143), Expect = 5e-09 Identities = 32/99 (32%), Positives = 52/99 (52%), Gaps = 1/99 (1%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKAR-MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITG 359 S SDD T+ +W+ K+ R + GH V+ + F+P G L S S+D++V++WN G Sbjct: 113 SASDDKTIRIWD--FEKRCSVRCLKGHTNYVSSIDFNPLGTLLVSGSWDETVRIWNLQDG 170 Query: 358 KFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDI 242 + H + +S SAD L + S D ++WD+ Sbjct: 171 TCLRMLPAHSEPIISVSISADGTLCATASYDGMARIWDV 209 Score = 46.6 bits (109), Expect = 4e-05 Identities = 29/121 (23%), Positives = 60/121 (49%), Gaps = 2/121 (1%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMT-GHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITG 359 SGS D T+ +W + RM H + + V S DG A+AS+D ++W+ ++G Sbjct: 155 SGSWDETVRIWN--LQDGTCLRMLPAHSEPIISVSISADGTLCATASYDGMARIWDVLSG 212 Query: 358 KFV-TAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 182 + + T + + ++ + + LL + +S +++WD R ++ + H + Y++ Sbjct: 213 QCLKTLVEPINVPLSNLQFTENRKYLLVSNLNSQIRLWDYRRNRVVRIFDSHVNTRYSMS 272 Query: 181 W 179 W Sbjct: 273 W 273 Score = 34.7 bits (78), Expect = 0.17 Identities = 26/139 (18%), Positives = 58/139 (41%), Gaps = 30/139 (21%) Frame = -2 Query: 448 VNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADS-------- 293 ++++ F+ + ++L ++ + ++LW+ + V F HV Y +SW S Sbjct: 226 LSNLQFTENRKYLLVSNLNSQIRLWDYRRNRVVRIFDSHVNTRYSMSWDCYSSKNIPKNT 285 Query: 292 --------------------RLLLSGSKDSTLKVWDIRARKLKQDLPGHAD--EVYAVDW 179 LL S+D T+++ D + + D H+D E ++ Sbjct: 286 EALPNNDSSYPDDAESFMHDAYLLIPSEDGTIQITDPSTKIIIDDSIRHSDDPETSLLNV 345 Query: 178 SPDGEKVVSGGKDRALKLW 122 + G +++ G D +++W Sbjct: 346 TSLGPFIITSGTDPYVRVW 364
>Y163_SYNY3 (Q55563) Hypothetical WD-repeat protein sll0163| Length = 1693 Score = 91.3 bits (225), Expect = 2e-18 Identities = 48/138 (34%), Positives = 76/138 (55%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 + S D T +W+ +P + GHQ +V FSP+G +A+ S D + +LW+ +GK Sbjct: 1523 TASVDNTARIWD--FLGRPLLTLAGHQSIVYQARFSPEGNLIATVSADHTARLWDR-SGK 1579 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 V GH V + WS D ++L++ S D T ++WD+ R+L L GH + V + ++S Sbjct: 1580 TVAVLYGHQGLVGTVDWSPDGQMLVTASNDGTARLWDLSGREL-LTLEGHGNWVRSAEFS 1638 Query: 175 PDGEKVVSGGKDRALKLW 122 PDG V++ D KLW Sbjct: 1639 PDGRWVLTSSADGTAKLW 1656 Score = 89.0 bits (219), Expect = 8e-18 Identities = 49/136 (36%), Positives = 75/136 (55%) Frame = -2 Query: 529 SDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFV 350 S D T LW T + A + HQ V FSPDGQW+ + S DK+ +LWN + GK + Sbjct: 1361 SRDKTARLW--TTEGECVAVLADHQGWVREGQFSPDGQWIVTGSADKTAQLWN-VLGKKL 1417 Query: 349 TAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPD 170 T RGH V + +S DS+ +++ SKD T +VW+ R+L L + ++A ++S D Sbjct: 1418 TVLRGHQDAVLNVRFSPDSQYIVTASKDGTARVWNNTGRELAV-LRHYEKNIFAAEFSAD 1476 Query: 169 GEKVVSGGKDRALKLW 122 G+ +V+ D +W Sbjct: 1477 GQFIVTASDDNTAGIW 1492 Score = 80.5 bits (197), Expect = 3e-15 Identities = 48/138 (34%), Positives = 72/138 (52%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 + S D T +W T + A + ++K + FS DGQ++ +AS D + +W I G+ Sbjct: 1441 TASKDGTARVWNNT--GRELAVLRHYEKNIFAAEFSADGQFIVTASDDNTAGIWE-IVGR 1497 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 V RGH VY +SADSR +L+ S D+T ++WD R L L GH VY +S Sbjct: 1498 EVGICRGHEGPVYFAQFSADSRYILTASVDNTARIWDFLGRPL-LTLAGHQSIVYQARFS 1556 Query: 175 PDGEKVVSGGKDRALKLW 122 P+G + + D +LW Sbjct: 1557 PEGNLIATVSADHTARLW 1574 Score = 80.5 bits (197), Expect = 3e-15 Identities = 46/138 (33%), Positives = 74/138 (53%) Frame = -2 Query: 529 SDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFV 350 S D T W+ IS++ +TGH V + +F+P G L + S DK+ +LW G+ V Sbjct: 1320 SADQTARQWD--ISQKDTITLTGHSHWVRNAHFNPKGDRLLTVSRDKTARLWT-TEGECV 1376 Query: 349 TAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPD 170 H V + +S D + +++GS D T ++W++ +KL L GH D V V +SPD Sbjct: 1377 AVLADHQGWVREGQFSPDGQWIVTGSADKTAQLWNVLGKKLTV-LRGHQDAVLNVRFSPD 1435 Query: 169 GEKVVSGGKDRALKLWMN 116 + +V+ KD ++W N Sbjct: 1436 SQYIVTASKDGTARVWNN 1453 Score = 78.6 bits (192), Expect = 1e-14 Identities = 43/138 (31%), Positives = 69/138 (50%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 + S D T LW+ + + GH V + FSPDGQW+ + S D + +LW+ ++ + Sbjct: 1154 TASRDGTARLWD--LEGREIGLCQGHTSWVRNAQFSPDGQWIVTCSADGTARLWD-LSSQ 1210 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 +GH V WS D + +++ S D T +VW R K L GH ++ +S Sbjct: 1211 CFAVLKGHQNWVNNALWSPDGQHIITSSSDGTARVWS-RHGKCLGTLRGHDHNIHGARFS 1269 Query: 175 PDGEKVVSGGKDRALKLW 122 DG+K+V+ D +LW Sbjct: 1270 LDGQKIVTYSTDNTARLW 1287 Score = 77.4 bits (189), Expect = 2e-14 Identities = 42/138 (30%), Positives = 74/138 (53%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 + S D T+ LW+ + A + GH+ V V+FSP Q+L ++ D + ++WN G+ Sbjct: 1072 TASADHTVKLWQR--HGEEVATLRGHEDWVRSVHFSPHHQFLVTSGQDNTARIWN-FAGE 1128 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 +T +GH V ++ ++LL+ S+D T ++WD+ R++ GH V +S Sbjct: 1129 QLTLCQGHADWVRNAEFNCHGQILLTASRDGTARLWDLEGREIGL-CQGHTSWVRNAQFS 1187 Query: 175 PDGEKVVSGGKDRALKLW 122 PDG+ +V+ D +LW Sbjct: 1188 PDGQWIVTCSADGTARLW 1205 Score = 73.6 bits (179), Expect = 3e-13 Identities = 45/140 (32%), Positives = 73/140 (52%), Gaps = 2/140 (1%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMT--GHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 362 + S D T +W S+ K T GH ++ FS DGQ + + S D + +LW Sbjct: 1236 TSSSDGTARVW----SRHGKCLGTLRGHDHNIHGARFSLDGQKIVTYSTDNTARLWTK-E 1290 Query: 361 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 182 G +T RGH +VY +SAD R + + S D T + WDI ++K L GH+ V Sbjct: 1291 GTLLTILRGHQKEVYDADFSADGRFVFTVSADQTARQWDI-SQKDTITLTGHSHWVRNAH 1349 Query: 181 WSPDGEKVVSGGKDRALKLW 122 ++P G+++++ +D+ +LW Sbjct: 1350 FNPKGDRLLTVSRDKTARLW 1369 Score = 68.9 bits (167), Expect = 8e-12 Identities = 36/116 (31%), Positives = 65/116 (56%) Frame = -2 Query: 469 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 290 + GHQ+ + + +S DGQ+ A+AS D +VKLW G+ V RGH V + +S + Sbjct: 1051 LRGHQEAITALDWSADGQYFATASADHTVKLWQR-HGEEVATLRGHEDWVRSVHFSPHHQ 1109 Query: 289 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 L++ +D+T ++W+ +L GHAD V +++ G+ +++ +D +LW Sbjct: 1110 FLVTSGQDNTARIWNFAGEQLTL-CQGHADWVRNAEFNCHGQILLTASRDGTARLW 1164 Score = 61.6 bits (148), Expect = 1e-09 Identities = 36/97 (37%), Positives = 55/97 (56%) Frame = -2 Query: 529 SDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFV 350 S D T LW+ S + A + GHQ +V V +SPDGQ L +AS D + +LW+ ++G+ + Sbjct: 1566 SADHTARLWDR--SGKTVAVLYGHQGLVGTVDWSPDGQMLVTASNDGTARLWD-LSGREL 1622 Query: 349 TAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIR 239 GH V +S D R +L+ S D T K+W ++ Sbjct: 1623 LTLEGHGNWVRSAEFSPDGRWVLTSSADGTAKLWPVK 1659 Score = 56.2 bits (134), Expect = 6e-08 Identities = 27/86 (31%), Positives = 46/86 (53%) Frame = -2 Query: 379 LWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHAD 200 LW+ G+ + RGH + + WSAD + + S D T+K+W ++ L GH D Sbjct: 1040 LWS-FHGELINVLRGHQEAITALDWSADGQYFATASADHTVKLWQRHGEEV-ATLRGHED 1097 Query: 199 EVYAVDWSPDGEKVVSGGKDRALKLW 122 V +V +SP + +V+ G+D ++W Sbjct: 1098 WVRSVHFSPHHQFLVTSGQDNTARIW 1123
>TAF5L_MOUSE (Q91WQ5) TAF5-like RNA polymerase II p300/CBP-associated| factor-associated factor 65 kDa subunit 5L (PCAF-associated factor 65 beta) (PAF65-beta) Length = 589 Score = 90.9 bits (224), Expect = 2e-18 Identities = 48/138 (34%), Positives = 75/138 (54%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SGS D T LW + P GH V+ V F P+ +LA+ S DK+V+LW+ G Sbjct: 401 SGSHDRTARLWSFDRT-YPLRIYAGHLADVDCVKFHPNSNYLATGSTDKTVRLWSAQQGN 459 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 V F GH V +S+S + + L S +D LK+WD+ + L ++L GH D + ++ +S Sbjct: 460 SVRLFTGHRGPVLSLSFSPNGKYLASAGEDQRLKLWDLASGTLFKELRGHTDSITSLAFS 519 Query: 175 PDGEKVVSGGKDRALKLW 122 PD + S D ++++W Sbjct: 520 PDSGLIASASMDNSVRVW 537 Score = 76.3 bits (186), Expect = 5e-14 Identities = 41/117 (35%), Positives = 65/117 (55%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 +GS D T+ LW + TGH+ V + FSP+G++LASA D+ +KLW+ +G Sbjct: 443 TGSTDKTVRLWSAQQGNSVRL-FTGHRGPVLSLSFSPNGKYLASAGEDQRLKLWDLASGT 501 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAV 185 RGH + +++S DS L+ S S D++++VWDIR+ G + E+ V Sbjct: 502 LFKELRGHTDSITSLAFSPDSGLIASASMDNSVRVWDIRSTCCNTPADGSSGELVGV 558 Score = 54.7 bits (130), Expect = 2e-07 Identities = 31/116 (26%), Positives = 51/116 (43%) Frame = -2 Query: 469 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 290 + GH V F D L S S D S++ W+ + ++GH V+ + S S Sbjct: 338 LRGHCGPVYSTRFLADSSGLLSCSEDMSIRYWDLGSFTNTVLYQGHAYPVWDVDISPFSL 397 Query: 289 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 SGS D T ++W + GH +V V + P+ + +G D+ ++LW Sbjct: 398 YFASGSHDRTARLWSFDRTYPLRIYAGHLADVDCVKFHPNSNYLATGSTDKTVRLW 453 Score = 53.9 bits (128), Expect = 3e-07 Identities = 31/81 (38%), Positives = 41/81 (50%) Frame = -2 Query: 364 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAV 185 TG + RGH VY + ADS LLS S+D +++ WD+ + GHA V+ V Sbjct: 331 TGTEMKILRGHCGPVYSTRFLADSSGLLSCSEDMSIRYWDLGSFTNTVLYQGHAYPVWDV 390 Query: 184 DWSPDGEKVVSGGKDRALKLW 122 D SP SG DR +LW Sbjct: 391 DISPFSLYFASGSHDRTARLW 411 Score = 37.0 bits (84), Expect = 0.035 Identities = 16/35 (45%), Positives = 26/35 (74%) Frame = -2 Query: 304 SADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHAD 200 S+DS+LL +G +S +K+W +R++KLK + P H D Sbjct: 277 SSDSKLLAAGFDNSCIKLWSLRSKKLKSE-PHHVD 310
>TAF5_HUMAN (Q15542) Transcription initiation factor TFIID subunit 5| (Transcription initiation factor TFIID 100 kDa subunit) (TAF(II)100) (TAFII-100) (TAFII100) Length = 800 Score = 90.9 bits (224), Expect = 2e-18 Identities = 47/138 (34%), Positives = 74/138 (53%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SG D LW T QP GH VN F P+ ++A+ S D++V+LW+ + G Sbjct: 602 SGGHDRVARLWA-TDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGN 660 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 V F GH ++ +++S + R L +G+ D + +WDI + +L GH D V ++ +S Sbjct: 661 CVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFS 720 Query: 175 PDGEKVVSGGKDRALKLW 122 DGE + SG D ++LW Sbjct: 721 RDGEILASGSMDNTVRLW 738 Score = 65.5 bits (158), Expect = 9e-11 Identities = 38/107 (35%), Positives = 62/107 (57%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 +GS D T+ LW+ ++ TGH+ ++ + FSP+G++LA+ + D V LW+ G Sbjct: 644 TGSADRTVRLWD-VLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGL 702 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDL 215 V +GH V + +S D +L SGS D+T+++WD A K +DL Sbjct: 703 MVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLWD--AIKAFEDL 747 Score = 56.2 bits (134), Expect = 6e-08 Identities = 37/137 (27%), Positives = 57/137 (41%) Frame = -2 Query: 532 GSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKF 353 G D T+ +W T K + +++ S D ++ + T Sbjct: 488 GFADSTVRVWSVTPKKLRSVKQASDLSLID------------KESDDVLERIMDEKTASE 535 Query: 352 VTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSP 173 + GH VY S+S D LLS S+D T+++W ++ GH V+ +SP Sbjct: 536 LKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSP 595 Query: 172 DGEKVVSGGKDRALKLW 122 G VSGG DR +LW Sbjct: 596 YGYYFVSGGHDRVARLW 612 Score = 40.8 bits (94), Expect = 0.002 Identities = 27/109 (24%), Positives = 46/109 (42%), Gaps = 31/109 (28%) Frame = -2 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLK---------------- 224 F+ A++G A + + DS L+ G DST++VW + +KL+ Sbjct: 466 FLNAYQGLTA----VDVTDDSSLIAGGFADSTVRVWSVTPKKLRSVKQASDLSLIDKESD 521 Query: 223 ---------------QDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 + L GH+ VY +SPD ++S +D ++LW Sbjct: 522 DVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLW 570
>PRP4_YEAST (P20053) U4/U6 small nuclear ribonucleoprotein PRP4| Length = 465 Score = 90.9 bits (224), Expect = 2e-18 Identities = 40/116 (34%), Positives = 67/116 (57%) Frame = -2 Query: 469 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 290 + GH++ ++ V + P G+++ SAS D + +LW+ T + + GH V+ +S+ D Sbjct: 261 LVGHERRISDVKYHPSGKFIGSASHDMTWRLWDASTHQELLLQEGHDKGVFSLSFQCDGS 320 Query: 289 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 L+ SG DS +WDIR+ L GH+ +Y V WSP+G +V +GG D + +W Sbjct: 321 LVCSGGMDSLSMLWDIRSGSKVMTLAGHSKPIYTVAWSPNGYQVATGGGDGIINVW 376 Score = 70.5 bits (171), Expect = 3e-12 Identities = 49/184 (26%), Positives = 71/184 (38%), Gaps = 46/184 (25%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 S S D T LW+ + + Q GH K V + F DG + S D LW+ +G Sbjct: 282 SASHDMTWRLWDAS-THQELLLQEGHDKGVFSLSFQCDGSLVCSGGMDSLSMLWDIRSGS 340 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQ--------------- 221 V GH +Y ++WS + + +G D + VWDIR R Q Sbjct: 341 KVMTLAGHSKPIYTVAWSPNGYQVATGGGDGIINVWDIRKRDEGQLNQILAHRNIVTQVR 400 Query: 220 -------------------------------DLPGHADEVYAVDWSPDGEKVVSGGKDRA 134 L GH D++ ++D S + +VSGG DR+ Sbjct: 401 FSKEDGGKKLVSCGYDNLINVYSSDTWLKMGSLAGHTDKIISLDISNNSHFLVSGGWDRS 460 Query: 133 LKLW 122 +KLW Sbjct: 461 IKLW 464 Score = 42.4 bits (98), Expect = 8e-04 Identities = 25/102 (24%), Positives = 52/102 (50%), Gaps = 5/102 (4%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMT---GHQKVVNHVYFSPD--GQWLASASFDKSVKLWN 371 +G D + +W+ I K+ + ++ H+ +V V FS + G+ L S +D + +++ Sbjct: 366 TGGGDGIINVWD--IRKRDEGQLNQILAHRNIVTQVRFSKEDGGKKLVSCGYDNLINVYS 423 Query: 370 GITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD 245 T + + GH + + S +S L+SG D ++K+W+ Sbjct: 424 SDTWLKMGSLAGHTDKIISLDISNNSHFLVSGGWDRSIKLWN 465 Score = 38.1 bits (87), Expect = 0.016 Identities = 30/117 (25%), Positives = 53/117 (45%), Gaps = 6/117 (5%) Frame = -2 Query: 454 KVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTA-FRGHVADVYQISWSADSR-LLL 281 K ++ V S D +A+ S+ +++ N T + +T HV + I W DS ++ Sbjct: 176 KPISAVSLSTDDMVVATGSWAGDLQVLNSQTLQPLTQKLDSHVGKIGAIDWHPDSNNQMI 235 Query: 280 SGSKDSTLKVWDIRAR----KLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 S ++D +K + +L DL GH + V + P G+ + S D +LW Sbjct: 236 SCAEDGLIKNFQYSNEEGGLRLLGDLVGHERRISDVKYHPSGKFIGSASHDMTWRLW 292
>WD51A_BOVIN (Q2TBP4) WD-repeat protein 51A| Length = 407 Score = 90.9 bits (224), Expect = 2e-18 Identities = 51/139 (36%), Positives = 72/139 (51%), Gaps = 1/139 (0%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKA-RMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITG 359 SGS D + +W + Q +A R GH+ V V FSP G LAS S DK+V++W Sbjct: 36 SGSMDSCLMVWH--MKPQTRAYRFAGHKDAVTCVNFSPSGHLLASGSRDKTVRIWVPNVK 93 Query: 358 KFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDW 179 T FR H A V + + +D + ++ S D T+KVW +K L H + V + Sbjct: 94 GESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVWSTHRQKFLFSLSQHINWVRCAKF 153 Query: 178 SPDGEKVVSGGKDRALKLW 122 SPDG +VS D+ +KLW Sbjct: 154 SPDGRLIVSASDDKTVKLW 172 Score = 87.4 bits (215), Expect = 2e-17 Identities = 48/138 (34%), Positives = 71/138 (51%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SGS D T+ +W P + K H V V+F DGQ +AS DK+VK+W+ K Sbjct: 78 SGSRDKTVRIWVPNV-KGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVWSTHRQK 136 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 F+ + H+ V +S D RL++S S D T+K+WD +R+ H V VD+ Sbjct: 137 FLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKTSRECVHSYCEHGGFVTYVDFH 196 Query: 175 PDGEKVVSGGKDRALKLW 122 P G + + G D +K+W Sbjct: 197 PSGTCIAAAGMDNTVKVW 214 Score = 80.5 bits (197), Expect = 3e-15 Identities = 47/138 (34%), Positives = 71/138 (51%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 S SDD T+ LW+ T S++ H V +V F P G +A+A D +VK+W+ T + Sbjct: 162 SASDDKTVKLWDKT-SRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHR 220 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 + ++ H A V +S+ L++ S DSTLK+ D+ +L L GH V +S Sbjct: 221 LLQHYQLHSAAVNALSFHPSGNYLVTASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFS 280 Query: 175 PDGEKVVSGGKDRALKLW 122 GE SGG D + +W Sbjct: 281 RTGEYFASGGSDEQVMVW 298 Score = 75.5 bits (184), Expect = 9e-14 Identities = 43/137 (31%), Positives = 72/137 (52%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 + SDD T+ +W T ++ ++ H V FSPDG+ + SAS DK+VKLW+ + + Sbjct: 120 TASDDKTVKVWS-THRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKTSRE 178 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 V ++ H V + + + + D+T+KVWD+R +L Q H+ V A+ + Sbjct: 179 CVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHSAAVNALSFH 238 Query: 175 PDGEKVVSGGKDRALKL 125 P G +V+ D LK+ Sbjct: 239 PSGNYLVTASSDSTLKI 255 Score = 62.4 bits (150), Expect = 8e-10 Identities = 34/114 (29%), Positives = 55/114 (48%) Frame = -2 Query: 463 GHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLL 284 GH+ V V FS + + LAS S D + +W+ F GH V +++S LL Sbjct: 17 GHRDAVTSVDFSLNTKQLASGSMDSCLMVWHMKPQTRAYRFAGHKDAVTCVNFSPSGHLL 76 Query: 283 LSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 SGS+D T+++W + H V +V + DG+ V+ D+ +K+W Sbjct: 77 ASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVW 130 Score = 59.3 bits (142), Expect = 7e-09 Identities = 26/75 (34%), Positives = 44/75 (58%) Frame = -2 Query: 343 FRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGE 164 F+GH V + +S +++ L SGS DS L VW ++ + GH D V V++SP G Sbjct: 15 FKGHRDAVTSVDFSLNTKQLASGSMDSCLMVWHMKPQTRAYRFAGHKDAVTCVNFSPSGH 74 Query: 163 KVVSGGKDRALKLWM 119 + SG +D+ +++W+ Sbjct: 75 LLASGSRDKTVRIWV 89
>TAF5L_HUMAN (O75529) TAF5-like RNA polymerase II p300/CBP-associated| factor-associated factor 65 kDa subunit 5L (PCAF-associated factor 65 beta) (PAF65-beta) Length = 589 Score = 90.5 bits (223), Expect = 3e-18 Identities = 47/138 (34%), Positives = 75/138 (54%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SGS D T LW + P GH V+ V F P+ +LA+ S DK+V+LW+ G Sbjct: 401 SGSHDRTARLWSFDRT-YPLRIYAGHLADVDCVKFHPNSNYLATGSTDKTVRLWSAQQGN 459 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 V F GH V +++S + + L S +D LK+WD+ + L ++L GH D + ++ +S Sbjct: 460 SVRLFTGHRGPVLSLAFSPNGKYLASAGEDQRLKLWDLASGTLYKELRGHTDNITSLTFS 519 Query: 175 PDGEKVVSGGKDRALKLW 122 PD + S D ++++W Sbjct: 520 PDSGLIASASMDNSVRVW 537 Score = 76.3 bits (186), Expect = 5e-14 Identities = 41/117 (35%), Positives = 65/117 (55%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 +GS D T+ LW + TGH+ V + FSP+G++LASA D+ +KLW+ +G Sbjct: 443 TGSTDKTVRLWSAQQGNSVRL-FTGHRGPVLSLAFSPNGKYLASAGEDQRLKLWDLASGT 501 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAV 185 RGH ++ +++S DS L+ S S D++++VWDIR G + E+ V Sbjct: 502 LYKELRGHTDNITSLTFSPDSGLIASASMDNSVRVWDIRNTYCSAPADGSSSELVGV 558 Score = 54.3 bits (129), Expect = 2e-07 Identities = 31/116 (26%), Positives = 51/116 (43%) Frame = -2 Query: 469 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 290 + GH V F D L S S D S++ W+ + ++GH V+ + S S Sbjct: 338 LRGHCGPVYSTRFLADSSGLLSCSEDMSIRYWDLGSFTNTVLYQGHAYPVWDLDISPYSL 397 Query: 289 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 SGS D T ++W + GH +V V + P+ + +G D+ ++LW Sbjct: 398 YFASGSHDRTARLWSFDRTYPLRIYAGHLADVDCVKFHPNSNYLATGSTDKTVRLW 453 Score = 52.4 bits (124), Expect = 8e-07 Identities = 38/144 (26%), Positives = 58/144 (40%), Gaps = 32/144 (22%) Frame = -2 Query: 457 QKVVNHVYFSPDGQWLASASFDKSVKLWN------------------------------- 371 ++++N SPD + LA+ + +KLW+ Sbjct: 268 EQLLNTAEISPDSKLLAAGFDNSCIKLWSLRSKKLKSEPHQVDVSRIHLACDILEEEDDE 327 Query: 370 -GITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEV 194 G + RGH VY + ADS LLS S+D +++ WD+ + GHA V Sbjct: 328 DDNAGTEMKILRGHCGPVYSTRFLADSSGLLSCSEDMSIRYWDLGSFTNTVLYQGHAYPV 387 Query: 193 YAVDWSPDGEKVVSGGKDRALKLW 122 + +D SP SG DR +LW Sbjct: 388 WDLDISPYSLYFASGSHDRTARLW 411
>KTNB1_MOUSE (Q8BG40) Katanin p80 WD40-containing subunit B1 (Katanin p80| subunit B1) (p80 katanin) Length = 658 Score = 90.1 bits (222), Expect = 3e-18 Identities = 50/132 (37%), Positives = 74/132 (56%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SGS D + LW+ K R GH + V + FSPDG+WLASA+ D +VKLW+ GK Sbjct: 122 SGSQDTNIKLWDIR-RKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGK 180 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 ++ F GH V + + + LL SGS D T++ WD+ ++ + G V +V ++ Sbjct: 181 MMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSVLFN 240 Query: 175 PDGEKVVSGGKD 140 PDG + SG +D Sbjct: 241 PDGCCLYSGCQD 252 Score = 84.3 bits (207), Expect = 2e-16 Identities = 44/138 (31%), Positives = 76/138 (55%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 +GS ++ +W+ +K + M GH+ + + F P G+++AS S D ++KLW+ Sbjct: 80 AGSQSGSIRVWDLEAAKILRTLM-GHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKG 138 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 V +RGH V + +S D + L S + D T+K+WD+ A K+ + PGH V V++ Sbjct: 139 CVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFH 198 Query: 175 PDGEKVVSGGKDRALKLW 122 P+ + SG DR ++ W Sbjct: 199 PNEYLLASGSSDRTIRFW 216 Score = 73.2 bits (178), Expect = 4e-13 Identities = 42/140 (30%), Positives = 71/140 (50%), Gaps = 2/140 (1%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARM--TGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 362 +G DD + LW +I+K P M TGH V V + + + + S S+++W+ Sbjct: 38 TGGDDCRVNLW--SINK-PNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEA 94 Query: 361 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 182 K + GH A++ + + + SGS+D+ +K+WDIR + GH+ V + Sbjct: 95 AKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLR 154 Query: 181 WSPDGEKVVSGGKDRALKLW 122 +SPDG+ + S D +KLW Sbjct: 155 FSPDGKWLASAADDHTVKLW 174 Score = 69.3 bits (168), Expect = 6e-12 Identities = 32/100 (32%), Positives = 56/100 (56%) Frame = -2 Query: 421 GQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDI 242 G+ LA+ D V LW+ + + GH + V + + L+++GS+ +++VWD+ Sbjct: 33 GRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDL 92 Query: 241 RARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 A K+ + L GH + ++D+ P GE V SG +D +KLW Sbjct: 93 EAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLW 132 Score = 51.2 bits (121), Expect = 2e-06 Identities = 30/91 (32%), Positives = 46/91 (50%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 S +DD T+ LW+ T K + GH VN V F P+ LAS S D++++ W+ + Sbjct: 164 SAADDHTVKLWDLTAGKM-MSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQ 222 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDS 263 V+ G V + ++ D L SG +DS Sbjct: 223 VVSCIEGEPGPVRSVLFNPDGCCLYSGCQDS 253 Score = 37.4 bits (85), Expect = 0.027 Identities = 17/60 (28%), Positives = 29/60 (48%) Frame = -2 Query: 301 ADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 A RLL +G D + +W I L GH V +V + E +V+G + ++++W Sbjct: 31 ASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVW 90
>KTNB1_HUMAN (Q9BVA0) Katanin p80 WD40-containing subunit B1 (Katanin p80| subunit B1) (p80 katanin) Length = 655 Score = 90.1 bits (222), Expect = 3e-18 Identities = 50/132 (37%), Positives = 74/132 (56%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SGS D + LW+ K R GH + V + FSPDG+WLASA+ D +VKLW+ GK Sbjct: 122 SGSQDTNIKLWDIR-RKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGK 180 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 ++ F GH V + + + LL SGS D T++ WD+ ++ + G V +V ++ Sbjct: 181 MMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSVLFN 240 Query: 175 PDGEKVVSGGKD 140 PDG + SG +D Sbjct: 241 PDGCCLYSGCQD 252 Score = 84.3 bits (207), Expect = 2e-16 Identities = 44/138 (31%), Positives = 76/138 (55%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 +GS ++ +W+ +K + M GH+ + + F P G+++AS S D ++KLW+ Sbjct: 80 AGSQSGSIRVWDLEAAKILRTLM-GHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKG 138 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 V +RGH V + +S D + L S + D T+K+WD+ A K+ + PGH V V++ Sbjct: 139 CVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFH 198 Query: 175 PDGEKVVSGGKDRALKLW 122 P+ + SG DR ++ W Sbjct: 199 PNEYLLASGSSDRTIRFW 216 Score = 73.2 bits (178), Expect = 4e-13 Identities = 42/140 (30%), Positives = 71/140 (50%), Gaps = 2/140 (1%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARM--TGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 362 +G DD + LW +I+K P M TGH V V + + + + S S+++W+ Sbjct: 38 TGGDDCRVNLW--SINK-PNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEA 94 Query: 361 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 182 K + GH A++ + + + SGS+D+ +K+WDIR + GH+ V + Sbjct: 95 AKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLR 154 Query: 181 WSPDGEKVVSGGKDRALKLW 122 +SPDG+ + S D +KLW Sbjct: 155 FSPDGKWLASAADDHTVKLW 174 Score = 69.3 bits (168), Expect = 6e-12 Identities = 32/100 (32%), Positives = 56/100 (56%) Frame = -2 Query: 421 GQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDI 242 G+ LA+ D V LW+ + + GH + V + + L+++GS+ +++VWD+ Sbjct: 33 GRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDL 92 Query: 241 RARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 A K+ + L GH + ++D+ P GE V SG +D +KLW Sbjct: 93 EAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLW 132 Score = 51.2 bits (121), Expect = 2e-06 Identities = 30/91 (32%), Positives = 46/91 (50%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 S +DD T+ LW+ T K + GH VN V F P+ LAS S D++++ W+ + Sbjct: 164 SAADDHTVKLWDLTAGKM-MSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQ 222 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDS 263 V+ G V + ++ D L SG +DS Sbjct: 223 VVSCIEGEPGPVRSVLFNPDGCCLYSGCQDS 253 Score = 37.4 bits (85), Expect = 0.027 Identities = 17/60 (28%), Positives = 29/60 (48%) Frame = -2 Query: 301 ADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 A RLL +G D + +W I L GH V +V + E +V+G + ++++W Sbjct: 31 ASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVW 90
>TAF5_MOUSE (Q8C092) Transcription initiation factor TFIID subunit 5| (Transcription initiation factor TFIID 100 kDa subunit) (TAF(II)100) (TAFII-100) (TAFII100) Length = 801 Score = 89.7 bits (221), Expect = 5e-18 Identities = 46/138 (33%), Positives = 74/138 (53%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SG D LW T QP GH VN + P+ ++A+ S D++V+LW+ + G Sbjct: 603 SGGHDRVARLWA-TDHYQPLRIFAGHLADVNCTRYHPNSNYVATGSADRTVRLWDVLNGN 661 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 V F GH ++ +++S + R L +G+ D + +WDI + +L GH D V ++ +S Sbjct: 662 CVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFS 721 Query: 175 PDGEKVVSGGKDRALKLW 122 DGE + SG D ++LW Sbjct: 722 RDGEILASGSMDNTVRLW 739 Score = 65.5 bits (158), Expect = 9e-11 Identities = 38/107 (35%), Positives = 62/107 (57%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 +GS D T+ LW+ ++ TGH+ ++ + FSP+G++LA+ + D V LW+ G Sbjct: 645 TGSADRTVRLWD-VLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGL 703 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDL 215 V +GH V + +S D +L SGS D+T+++WD A K +DL Sbjct: 704 MVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLWD--AVKAFEDL 748 Score = 56.2 bits (134), Expect = 6e-08 Identities = 37/137 (27%), Positives = 57/137 (41%) Frame = -2 Query: 532 GSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKF 353 G D T+ +W T K + +++ S D ++ + T Sbjct: 489 GFADSTVRVWSVTPKKLRSVKQASDLSLID------------KESDDVLERIMDEKTASE 536 Query: 352 VTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSP 173 + GH VY S+S D LLS S+D T+++W ++ GH V+ +SP Sbjct: 537 LKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSP 596 Query: 172 DGEKVVSGGKDRALKLW 122 G VSGG DR +LW Sbjct: 597 YGYYFVSGGHDRVARLW 613 Score = 40.8 bits (94), Expect = 0.002 Identities = 27/109 (24%), Positives = 46/109 (42%), Gaps = 31/109 (28%) Frame = -2 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLK---------------- 224 F+ A++G A + + DS L+ G DST++VW + +KL+ Sbjct: 467 FLNAYQGLTA----VDVTDDSSLIAGGFADSTVRVWSVTPKKLRSVKQASDLSLIDKESD 522 Query: 223 ---------------QDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 + L GH+ VY +SPD ++S +D ++LW Sbjct: 523 DVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLW 571
>GBLP_TRYBR (P69104) Guanine nucleotide-binding protein beta subunit-like| protein (Activated protein kinase C receptor homolog) (Track) Length = 318 Score = 89.7 bits (221), Expect = 5e-18 Identities = 52/149 (34%), Positives = 79/149 (53%), Gaps = 11/149 (7%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQ--------PKARMTGHQKVVNHVYFSPDGQWLASASFDKSVK 380 S S D T+ W P + P R+ GH V+ V S +G + SAS+D S++ Sbjct: 33 STSRDKTLLSWGPNPDRHSSECSYGLPDRRLEGHSAFVSDVALSNNGNFAVSASWDHSLR 92 Query: 379 LWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPG-HA 203 LWN G+ F GH DV +++S D+R ++SG +D+ L+VW+++ + G H Sbjct: 93 LWNLQNGQCQYKFLGHTKDVLSVAFSPDNRQIVSGGRDNALRVWNVKGECMHTLSRGAHT 152 Query: 202 DEVYAVDWSP--DGEKVVSGGKDRALKLW 122 D V V +SP D +VSGG D +K+W Sbjct: 153 DWVSCVRFSPSLDAPVIVSGGWDNLVKVW 181 Score = 52.8 bits (125), Expect = 6e-07 Identities = 31/100 (31%), Positives = 45/100 (45%), Gaps = 2/100 (2%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSP--DGQWLASASFDKSVKLWNGIT 362 SG D + +W H V+ V FSP D + S +D VK+W+ T Sbjct: 126 SGGRDNALRVWNVKGECMHTLSRGAHTDWVSCVRFSPSLDAPVIVSGGWDNLVKVWDLAT 185 Query: 361 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDI 242 G+ VT +GH V ++ S D L S KD ++WD+ Sbjct: 186 GRLVTDLKGHTNYVTSVTVSPDGSLCASSDKDGVARLWDL 225 Score = 48.9 bits (115), Expect = 9e-06 Identities = 32/123 (26%), Positives = 59/123 (47%), Gaps = 7/123 (5%) Frame = -2 Query: 469 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 290 + GH V V SPDG AS+ D +LW+ G+ ++ A + QI +S +R Sbjct: 192 LKGHTNYVTSVTVSPDGSLCASSDKDGVARLWDLTKGEALSEMAAG-APINQICFS-PNR 249 Query: 289 LLLSGSKDSTLKVWDIRARKLKQDL-PGH------ADEVYAVDWSPDGEKVVSGGKDRAL 131 + + + ++++D+ + + +L P H E ++ WS DG + SG D + Sbjct: 250 YWMCAATEKGIRIFDLENKDIIVELAPEHQGSKKIVPECVSIAWSADGSTLYSGYTDNVI 309 Query: 130 KLW 122 ++W Sbjct: 310 RVW 312 Score = 40.4 bits (93), Expect = 0.003 Identities = 27/105 (25%), Positives = 49/105 (46%), Gaps = 7/105 (6%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWN----G 368 S D LW+ T + G +N + FSP+ W+ +A+ +K +++++ Sbjct: 213 SSDKDGVARLWDLTKGEALSEMAAGAP--INQICFSPNRYWMCAAT-EKGIRIFDLENKD 269 Query: 367 ITGKFVTAFRGH---VADVYQISWSADSRLLLSGSKDSTLKVWDI 242 I + +G V + I+WSAD L SG D+ ++VW + Sbjct: 270 IIVELAPEHQGSKKIVPECVSIAWSADGSTLYSGYTDNVIRVWGV 314
>GBLP_TRYBB (P69103) Guanine nucleotide-binding protein beta subunit-like| protein (Activated protein kinase C receptor homolog) Length = 318 Score = 89.7 bits (221), Expect = 5e-18 Identities = 52/149 (34%), Positives = 79/149 (53%), Gaps = 11/149 (7%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQ--------PKARMTGHQKVVNHVYFSPDGQWLASASFDKSVK 380 S S D T+ W P + P R+ GH V+ V S +G + SAS+D S++ Sbjct: 33 STSRDKTLLSWGPNPDRHSSECSYGLPDRRLEGHSAFVSDVALSNNGNFAVSASWDHSLR 92 Query: 379 LWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPG-HA 203 LWN G+ F GH DV +++S D+R ++SG +D+ L+VW+++ + G H Sbjct: 93 LWNLQNGQCQYKFLGHTKDVLSVAFSPDNRQIVSGGRDNALRVWNVKGECMHTLSRGAHT 152 Query: 202 DEVYAVDWSP--DGEKVVSGGKDRALKLW 122 D V V +SP D +VSGG D +K+W Sbjct: 153 DWVSCVRFSPSLDAPVIVSGGWDNLVKVW 181 Score = 52.8 bits (125), Expect = 6e-07 Identities = 31/100 (31%), Positives = 45/100 (45%), Gaps = 2/100 (2%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSP--DGQWLASASFDKSVKLWNGIT 362 SG D + +W H V+ V FSP D + S +D VK+W+ T Sbjct: 126 SGGRDNALRVWNVKGECMHTLSRGAHTDWVSCVRFSPSLDAPVIVSGGWDNLVKVWDLAT 185 Query: 361 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDI 242 G+ VT +GH V ++ S D L S KD ++WD+ Sbjct: 186 GRLVTDLKGHTNYVTSVTVSPDGSLCASSDKDGVARLWDL 225 Score = 48.9 bits (115), Expect = 9e-06 Identities = 32/123 (26%), Positives = 59/123 (47%), Gaps = 7/123 (5%) Frame = -2 Query: 469 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 290 + GH V V SPDG AS+ D +LW+ G+ ++ A + QI +S +R Sbjct: 192 LKGHTNYVTSVTVSPDGSLCASSDKDGVARLWDLTKGEALSEMAAG-APINQICFS-PNR 249 Query: 289 LLLSGSKDSTLKVWDIRARKLKQDL-PGH------ADEVYAVDWSPDGEKVVSGGKDRAL 131 + + + ++++D+ + + +L P H E ++ WS DG + SG D + Sbjct: 250 YWMCAATEKGIRIFDLENKDIIVELAPEHQGSKKIVPECVSIAWSADGSTLYSGYTDNVI 309 Query: 130 KLW 122 ++W Sbjct: 310 RVW 312 Score = 40.4 bits (93), Expect = 0.003 Identities = 27/105 (25%), Positives = 49/105 (46%), Gaps = 7/105 (6%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWN----G 368 S D LW+ T + G +N + FSP+ W+ +A+ +K +++++ Sbjct: 213 SSDKDGVARLWDLTKGEALSEMAAGAP--INQICFSPNRYWMCAAT-EKGIRIFDLENKD 269 Query: 367 ITGKFVTAFRGH---VADVYQISWSADSRLLLSGSKDSTLKVWDI 242 I + +G V + I+WSAD L SG D+ ++VW + Sbjct: 270 IIVELAPEHQGSKKIVPECVSIAWSADGSTLYSGYTDNVIRVWGV 314
>WD51B_MOUSE (Q8BHD1) WD-repeat protein 51B| Length = 476 Score = 89.7 bits (221), Expect = 5e-18 Identities = 51/141 (36%), Positives = 78/141 (55%), Gaps = 3/141 (2%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARM---TGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGI 365 + S D + LW S +P AR GH+ VV + FSP G LASAS D++V+LW Sbjct: 35 TASWDTFLMLW----SLKPHARAYRYVGHKDVVTSLQFSPQGNLLASASRDRTVRLWVLD 90 Query: 364 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAV 185 + F+ H A V + +SAD +LL++ S+D ++KVW + ++ L H V Sbjct: 91 RKGKSSEFKAHTAPVRSVDFSADGQLLVTASEDKSIKVWSMFRQRFLYSLYRHTHWVRCA 150 Query: 184 DWSPDGEKVVSGGKDRALKLW 122 +SPDG +VS +D+ +K+W Sbjct: 151 KFSPDGRLIVSCSEDKTIKIW 171 Score = 82.4 bits (202), Expect = 7e-16 Identities = 47/138 (34%), Positives = 71/138 (51%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 S S D T+ LW K + H V V FS DGQ L +AS DKS+K+W+ + Sbjct: 77 SASRDRTVRLWVLD-RKGKSSEFKAHTAPVRSVDFSADGQLLVTASEDKSIKVWSMFRQR 135 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 F+ + H V +S D RL++S S+D T+K+WD ++ + VD++ Sbjct: 136 FLYSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFANFVDFN 195 Query: 175 PDGEKVVSGGKDRALKLW 122 P+G + S G D A+K+W Sbjct: 196 PNGTCIASAGSDHAVKIW 213 Score = 77.0 bits (188), Expect = 3e-14 Identities = 45/138 (32%), Positives = 73/138 (52%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 S S+D T+ +W+ T +KQ + N V F+P+G +ASA D +VK+W+ K Sbjct: 161 SCSEDKTIKIWDTT-NKQCVNNFSDSVGFANFVDFNPNGTCIASAGSDHAVKIWDIRMNK 219 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 + ++ H V +S+ L++ S D T+K+ D+ +L L GH V+ V +S Sbjct: 220 LLQHYQVHSCGVNCLSFHPLGNSLVTASSDGTVKMLDLIEGRLIYTLQGHTGPVFTVSFS 279 Query: 175 PDGEKVVSGGKDRALKLW 122 DGE + SGG D + +W Sbjct: 280 KDGELLTSGGADAQVLIW 297 Score = 68.6 bits (166), Expect = 1e-11 Identities = 33/114 (28%), Positives = 62/114 (54%) Frame = -2 Query: 463 GHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLL 284 GH+ + FSP+ + +A+AS+D + LW+ + GH V + +S LL Sbjct: 16 GHKAAITSADFSPNCKQIATASWDTFLMLWSLKPHARAYRYVGHKDVVTSLQFSPQGNLL 75 Query: 283 LSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 S S+D T+++W + + + H V +VD+S DG+ +V+ +D+++K+W Sbjct: 76 ASASRDRTVRLWVLDRKGKSSEFKAHTAPVRSVDFSADGQLLVTASEDKSIKVW 129 Score = 63.5 bits (153), Expect = 3e-10 Identities = 33/112 (29%), Positives = 54/112 (48%) Frame = -2 Query: 460 HQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLL 281 H V FSPDG+ + S S DK++K+W+ + V F V + ++ + + Sbjct: 143 HTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFANFVDFNPNGTCIA 202 Query: 280 SGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKL 125 S D +K+WDIR KL Q H+ V + + P G +V+ D +K+ Sbjct: 203 SAGSDHAVKIWDIRMNKLLQHYQVHSCGVNCLSFHPLGNSLVTASSDGTVKM 254 Score = 49.7 bits (117), Expect = 5e-06 Identities = 21/76 (27%), Positives = 41/76 (53%) Frame = -2 Query: 346 AFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDG 167 +F+GH A + +S + + + + S D+ L +W ++ GH D V ++ +SP G Sbjct: 13 SFKGHKAAITSADFSPNCKQIATASWDTFLMLWSLKPHARAYRYVGHKDVVTSLQFSPQG 72 Query: 166 EKVVSGGKDRALKLWM 119 + S +DR ++LW+ Sbjct: 73 NLLASASRDRTVRLWV 88
>WD51B_HUMAN (Q8TC44) WD-repeat protein 51B| Length = 478 Score = 89.4 bits (220), Expect = 6e-18 Identities = 47/118 (39%), Positives = 69/118 (58%), Gaps = 1/118 (0%) Frame = -2 Query: 472 RMTGHQKVVNHVYFSPDGQWLASASFDKSVKLW-NGITGKFVTAFRGHVADVYQISWSAD 296 R GH+ VV V FSP G LASAS D++V+LW GKF + F+ H A V + +SAD Sbjct: 55 RYVGHKDVVTSVQFSPHGNLLASASRDRTVRLWIPDKRGKF-SEFKAHTAPVRSVDFSAD 113 Query: 295 SRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 + L + S+D ++KVW + ++ L H V +SPDG +VS +D+ +K+W Sbjct: 114 GQFLATASEDKSIKVWSMYRQRFLYSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIW 171 Score = 84.7 bits (208), Expect = 1e-16 Identities = 49/139 (35%), Positives = 75/139 (53%), Gaps = 1/139 (0%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPK-ARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITG 359 S S D T+ LW P K+ K + H V V FS DGQ+LA+AS DKS+K+W+ Sbjct: 77 SASRDRTVRLWIP--DKRGKFSEFKAHTAPVRSVDFSADGQFLATASEDKSIKVWSMYRQ 134 Query: 358 KFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDW 179 +F+ + H V +S D RL++S S+D T+K+WD ++ + VD+ Sbjct: 135 RFLYSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFANFVDF 194 Query: 178 SPDGEKVVSGGKDRALKLW 122 +P G + S G D+ +K+W Sbjct: 195 NPSGTCIASAGSDQTVKVW 213 Score = 80.5 bits (197), Expect = 3e-15 Identities = 47/138 (34%), Positives = 71/138 (51%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 S S+D T+ +W+ T +KQ + N V F+P G +ASA D++VK+W+ K Sbjct: 161 SCSEDKTIKIWDTT-NKQCVNNFSDSVGFANFVDFNPSGTCIASAGSDQTVKVWDVRVNK 219 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 + ++ H V IS+ L++ S D TLK+ D+ +L L GH V+ V +S Sbjct: 220 LLQHYQVHSGGVNCISFHPSGNYLITASSDGTLKILDLLEGRLIYTLQGHTGPVFTVSFS 279 Query: 175 PDGEKVVSGGKDRALKLW 122 GE SGG D + LW Sbjct: 280 KGGELFASGGADTQVLLW 297 Score = 69.3 bits (168), Expect = 6e-12 Identities = 35/114 (30%), Positives = 61/114 (53%) Frame = -2 Query: 463 GHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLL 284 GH+ + + SP+G+ LA+AS+D + LWN + GH V + +S LL Sbjct: 16 GHKAAITSLDLSPNGKQLATASWDTFLMLWNFKPHARAYRYVGHKDVVTSVQFSPHGNLL 75 Query: 283 LSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 S S+D T+++W R + H V +VD+S DG+ + + +D+++K+W Sbjct: 76 ASASRDRTVRLWIPDKRGKFSEFKAHTAPVRSVDFSADGQFLATASEDKSIKVW 129 Score = 68.9 bits (167), Expect = 8e-12 Identities = 34/112 (30%), Positives = 54/112 (48%) Frame = -2 Query: 460 HQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLL 281 H V FSPDG+ + S S DK++K+W+ + V F V + ++ + Sbjct: 143 HTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFANFVDFNPSGTCIA 202 Query: 280 SGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKL 125 S D T+KVWD+R KL Q H+ V + + P G +++ D LK+ Sbjct: 203 SAGSDQTVKVWDVRVNKLLQHYQVHSGGVNCISFHPSGNYLITASSDGTLKI 254 Score = 50.8 bits (120), Expect = 2e-06 Identities = 23/75 (30%), Positives = 40/75 (53%) Frame = -2 Query: 343 FRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGE 164 F+GH A + + S + + L + S D+ L +W+ + GH D V +V +SP G Sbjct: 14 FKGHKAAITSLDLSPNGKQLATASWDTFLMLWNFKPHARAYRYVGHKDVVTSVQFSPHGN 73 Query: 163 KVVSGGKDRALKLWM 119 + S +DR ++LW+ Sbjct: 74 LLASASRDRTVRLWI 88
>YKY4_CAEEL (Q17963) Hypothetical WD-repeat protein C14B1.4| Length = 376 Score = 89.4 bits (220), Expect = 6e-18 Identities = 42/116 (36%), Positives = 70/116 (60%) Frame = -2 Query: 469 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 290 + GH K ++ FSP G++L ++S DK+VK+WN GH V I+WS+DSR Sbjct: 83 LEGHTKSISSAKFSPCGKYLGTSSADKTVKIWNMDHMICERTLTGHKLGVNDIAWSSDSR 142 Query: 289 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 ++S S D TLK+++I ++ + L GH + V+ +++P VVSG D ++++W Sbjct: 143 CVVSASDDKTLKIFEIVTSRMTKTLKGHNNYVFCCNFNPQSSLVVSGSFDESVRIW 198 Score = 84.7 bits (208), Expect = 1e-16 Identities = 38/116 (32%), Positives = 71/116 (61%) Frame = -2 Query: 469 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 290 +TGH+ VN + +S D + + SAS DK++K++ +T + +GH V+ +++ S Sbjct: 125 LTGHKLGVNDIAWSSDSRCVVSASDDKTLKIFEIVTSRMTKTLKGHNNYVFCCNFNPQSS 184 Query: 289 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 L++SGS D ++++WD++ + LP H+D V AV ++ DG + SG D +++W Sbjct: 185 LVVSGSFDESVRIWDVKTGMCIKTLPAHSDPVSAVSFNRDGSLIASGSYDGLVRIW 240 Score = 77.4 bits (189), Expect = 2e-14 Identities = 44/139 (31%), Positives = 72/139 (51%), Gaps = 1/139 (0%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 S SDD T+ ++E S+ K + GH V F+P + S SFD+SV++W+ TG Sbjct: 146 SASDDKTLKIFEIVTSRMTKT-LKGHNNYVFCCNFNPQSSLVVSGSFDESVRIWDVKTGM 204 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD-IRARKLKQDLPGHADEVYAVDW 179 + H V +S++ D L+ SGS D +++WD + +K + V V + Sbjct: 205 CIKTLPAHSDPVSAVSFNRDGSLIASGSYDGLVRIWDTANGQCIKTLVDDENPPVAFVKF 264 Query: 178 SPDGEKVVSGGKDRALKLW 122 SP+G+ +++ D LKLW Sbjct: 265 SPNGKYILASNLDSTLKLW 283 Score = 70.1 bits (170), Expect = 4e-12 Identities = 40/143 (27%), Positives = 72/143 (50%), Gaps = 5/143 (3%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SGS D + +W+ + K + V V FSP+G+++ +++ D ++KLW+ GK Sbjct: 230 SGSYDGLVRIWDTANGQCIKTLVDDENPPVAFVKFSPNGKYILASNLDSTLKLWDFSKGK 289 Query: 355 FVTAFRGHVADVYQISWS---ADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAV 185 + + GH Y I + + ++SGS+D + +W+++ R++ Q L GH V A Sbjct: 290 TLKQYTGHENSKYCIFANFSVTGGKWIISGSEDCKIYIWNLQTREIVQCLEGHTQPVLAS 349 Query: 184 DWSPDGEKVVSGG--KDRALKLW 122 D P + SG D + +W Sbjct: 350 DCHPVQNIIASGALEPDNKIHIW 372 Score = 46.2 bits (108), Expect = 6e-05 Identities = 23/79 (29%), Positives = 38/79 (48%) Frame = -2 Query: 358 KFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDW 179 K + GH + +S + L + S D T+K+W++ ++ L GH V + W Sbjct: 78 KLMCTLEGHTKSISSAKFSPCGKYLGTSSADKTVKIWNMDHMICERTLTGHKLGVNDIAW 137 Query: 178 SPDGEKVVSGGKDRALKLW 122 S D VVS D+ LK++ Sbjct: 138 SSDSRCVVSASDDKTLKIF 156
>WD51B_PONPY (Q5RD06) WD-repeat protein 51B| Length = 451 Score = 89.4 bits (220), Expect = 6e-18 Identities = 47/118 (39%), Positives = 69/118 (58%), Gaps = 1/118 (0%) Frame = -2 Query: 472 RMTGHQKVVNHVYFSPDGQWLASASFDKSVKLW-NGITGKFVTAFRGHVADVYQISWSAD 296 R GH+ VV V FSP G LASAS D++V+LW GKF + F+ H A V + +SAD Sbjct: 55 RYVGHKDVVTSVQFSPHGNLLASASRDRTVRLWIPDKRGKF-SEFKAHTAPVRSVDFSAD 113 Query: 295 SRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 + L + S+D ++KVW + ++ L H V +SPDG +VS +D+ +K+W Sbjct: 114 GQFLATASEDKSIKVWSMYRQRFLYSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIW 171 Score = 84.7 bits (208), Expect = 1e-16 Identities = 49/139 (35%), Positives = 75/139 (53%), Gaps = 1/139 (0%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPK-ARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITG 359 S S D T+ LW P K+ K + H V V FS DGQ+LA+AS DKS+K+W+ Sbjct: 77 SASRDRTVRLWIP--DKRGKFSEFKAHTAPVRSVDFSADGQFLATASEDKSIKVWSMYRQ 134 Query: 358 KFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDW 179 +F+ + H V +S D RL++S S+D T+K+WD ++ + VD+ Sbjct: 135 RFLYSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFANFVDF 194 Query: 178 SPDGEKVVSGGKDRALKLW 122 +P G + S G D+ +K+W Sbjct: 195 NPSGTCIASAGSDQTVKVW 213 Score = 80.1 bits (196), Expect = 4e-15 Identities = 47/138 (34%), Positives = 71/138 (51%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 S S+D T+ +W+ T +KQ + N V F+P G +ASA D++VK+W+ K Sbjct: 161 SCSEDKTIKIWDTT-NKQCVNNFSDSVGFANFVDFNPSGTCIASAGSDQTVKVWDVRVNK 219 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 + ++ H V IS+ L++ S D TLK+ D+ +L L GH V+ V +S Sbjct: 220 LLQHYQVHSGGVNCISFHPSDNYLVTASSDGTLKILDLLEGRLIYTLQGHTGPVFTVSFS 279 Query: 175 PDGEKVVSGGKDRALKLW 122 GE SGG D + LW Sbjct: 280 KGGELFASGGADTQVLLW 297 Score = 69.3 bits (168), Expect = 6e-12 Identities = 35/114 (30%), Positives = 61/114 (53%) Frame = -2 Query: 463 GHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLL 284 GH+ + + SP+G+ LA+AS+D + LWN + GH V + +S LL Sbjct: 16 GHKAAITSLDLSPNGKQLATASWDTFLMLWNFKPHARAYRYVGHKDVVTSVQFSPHGNLL 75 Query: 283 LSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 S S+D T+++W R + H V +VD+S DG+ + + +D+++K+W Sbjct: 76 ASASRDRTVRLWIPDKRGKFSEFKAHTAPVRSVDFSADGQFLATASEDKSIKVW 129 Score = 66.6 bits (161), Expect = 4e-11 Identities = 34/112 (30%), Positives = 53/112 (47%) Frame = -2 Query: 460 HQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLL 281 H V FSPDG+ + S S DK++K+W+ + V F V + ++ + Sbjct: 143 HTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFANFVDFNPSGTCIA 202 Query: 280 SGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKL 125 S D T+KVWD+R KL Q H+ V + + P +V+ D LK+ Sbjct: 203 SAGSDQTVKVWDVRVNKLLQHYQVHSGGVNCISFHPSDNYLVTASSDGTLKI 254 Score = 50.8 bits (120), Expect = 2e-06 Identities = 23/75 (30%), Positives = 40/75 (53%) Frame = -2 Query: 343 FRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGE 164 F+GH A + + S + + L + S D+ L +W+ + GH D V +V +SP G Sbjct: 14 FKGHKAAITSLDLSPNGKQLATASWDTFLMLWNFKPHARAYRYVGHKDVVTSVQFSPHGN 73 Query: 163 KVVSGGKDRALKLWM 119 + S +DR ++LW+ Sbjct: 74 LLASASRDRTVRLWI 88
>GBLP_SCHPO (Q10281) Guanine nucleotide-binding protein beta subunit-like| protein (Receptor of activated protein kinase C) Length = 314 Score = 89.4 bits (220), Expect = 6e-18 Identities = 53/145 (36%), Positives = 83/145 (57%), Gaps = 7/145 (4%) Frame = -2 Query: 535 SGSDDFTMFLW----EPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNG 368 SGS D ++ LW + + R+TGH V+ S D + SAS+DK+++LW+ Sbjct: 33 SGSRDKSIILWNLVRDDVNYGVAQRRLTGHSHFVSDCALSFDSHYALSASWDKTIRLWDL 92 Query: 367 ITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRAR-KLKQDLPGHADEVY 191 G+ F GH +DV +S S D+R ++SGS+D T+K+W+I K GH+D V Sbjct: 93 EKGECTHQFVGHTSDVLSVSISPDNRQVVSGSRDKTIKIWNIIGNCKYTITDGGHSDWVS 152 Query: 190 AVDWSPDGEKV--VSGGKDRALKLW 122 V +SP+ + + VS G D+A+K+W Sbjct: 153 CVRFSPNPDNLTFVSAGWDKAVKVW 177 Score = 72.0 bits (175), Expect = 1e-12 Identities = 42/125 (33%), Positives = 62/125 (49%), Gaps = 6/125 (4%) Frame = -2 Query: 478 KARMTGHQKVVNHVYFSPDG-QWLASASFDKSVKLWNGIT-----GKFVTAFRGHVADVY 317 +A + GH V + +P+ L S S DKS+ LWN + G GH V Sbjct: 8 RATLEGHSGWVTSLSTAPENPDILLSGSRDKSIILWNLVRDDVNYGVAQRRLTGHSHFVS 67 Query: 316 QISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDR 137 + S DS LS S D T+++WD+ + GH +V +V SPD +VVSG +D+ Sbjct: 68 DCALSFDSHYALSASWDKTIRLWDLEKGECTHQFVGHTSDVLSVSISPDNRQVVSGSRDK 127 Query: 136 ALKLW 122 +K+W Sbjct: 128 TIKIW 132 Score = 59.7 bits (143), Expect = 5e-09 Identities = 49/189 (25%), Positives = 73/189 (38%), Gaps = 51/189 (26%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSP--DGQWLASASFDKSVKLWNGIT 362 SGS D T+ +W + + GH V+ V FSP D SA +DK+VK+W+ T Sbjct: 122 SGSRDKTIKIWNIIGNCKYTITDGGHSDWVSCVRFSPNPDNLTFVSAGWDKAVKVWDLET 181 Query: 361 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDI-------------------- 242 T+ GH V ++ S D L SG +D TL +WD+ Sbjct: 182 FSLRTSHYGHTGYVSAVTISPDGSLCASGGRDGTLMLWDLNESTHLYSLEAKANINALVF 241 Query: 241 ------------------------RARKLKQDLPG-----HADEVYAVDWSPDGEKVVSG 149 + +L D G E ++ WSPDG+ + SG Sbjct: 242 SPNRYWLCAATGSSIRIFDLETQEKVDELTVDFVGVGKKSSEPECISLTWSPDGQTLFSG 301 Query: 148 GKDRALKLW 122 D +++W Sbjct: 302 WTDNLIRVW 310 Score = 39.7 bits (91), Expect = 0.005 Identities = 26/107 (24%), Positives = 52/107 (48%), Gaps = 9/107 (8%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWN----- 371 SG D T+ LW+ +++ + +N + FSP+ WL +A+ S+++++ Sbjct: 209 SGGRDGTLMLWD--LNESTHLYSLEAKANINALVFSPNRYWLCAAT-GSSIRIFDLETQE 265 Query: 370 ---GITGKFV-TAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDI 242 +T FV + + ++WS D + L SG D+ ++VW + Sbjct: 266 KVDELTVDFVGVGKKSSEPECISLTWSPDGQTLFSGWTDNLIRVWQV 312
>GBLP_BRARE (O42248) Guanine nucleotide-binding protein beta subunit 2-like 1| (Receptor of activated protein kinase C) (RACK) Length = 317 Score = 88.2 bits (217), Expect = 1e-17 Identities = 50/145 (34%), Positives = 81/145 (55%), Gaps = 7/145 (4%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQ----PKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNG 368 S S D T+ +W+ T + P+ + GH V+ V S DGQ+ S S+D +++LW+ Sbjct: 33 SASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDL 92 Query: 367 ITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD-IRARKLKQDLPGHADEVY 191 TG F GH DV +++SAD+R ++SGS+D T+K+W+ + K H + V Sbjct: 93 TTGTTTRRFVGHTKDVLSVAFSADNRQIVSGSRDKTIKLWNTLGVCKYTIQDDSHTEWVS 152 Query: 190 AVDWSPDGEK--VVSGGKDRALKLW 122 V +SP+ +VS G D+ +K+W Sbjct: 153 CVRFSPNSSNPIIVSCGWDKMVKVW 177 Score = 56.6 bits (135), Expect = 4e-08 Identities = 40/124 (32%), Positives = 58/124 (46%), Gaps = 2/124 (1%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQ--WLASASFDKSVKLWNGIT 362 SGS D T+ LW + + H + V+ V FSP+ + S +DK VK+WN Sbjct: 122 SGSRDKTIKLWNTLGVCKYTIQDDSHTEWVSCVRFSPNSSNPIIVSCGWDKMVKVWNLAN 181 Query: 361 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 182 K T GH + ++ S D L SG KD +WD+ K L G D + A+ Sbjct: 182 CKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDG-GDTINALC 240 Query: 181 WSPD 170 +SP+ Sbjct: 241 FSPN 244 Score = 52.4 bits (124), Expect = 8e-07 Identities = 33/128 (25%), Positives = 56/128 (43%), Gaps = 9/128 (7%) Frame = -2 Query: 478 KARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSA 299 K GH +N V SPDG AS D LW+ GK + G D + Sbjct: 185 KTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDG--GDTINALCFS 242 Query: 298 DSRLLLSGSKDSTLKVWDIRAR----KLKQDL-----PGHADEVYAVDWSPDGEKVVSGG 146 +R L + ++K+WD+ + +L+QD+ + ++ WS DG+ + +G Sbjct: 243 PNRYWLCAATGPSIKIWDLEGKIIVDELRQDIITTNSKAEPPQCTSLAWSADGQTLFAGY 302 Query: 145 KDRALKLW 122 D +++W Sbjct: 303 TDNLIRVW 310 Score = 44.3 bits (103), Expect = 2e-04 Identities = 29/108 (26%), Positives = 49/108 (45%), Gaps = 10/108 (9%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SG D LW+ K G +N + FSP+ WL +A+ S+K+W+ + GK Sbjct: 209 SGGKDGQAMLWDLNEGKHLYTLDGGD--TINALCFSPNRYWLCAAT-GPSIKIWD-LEGK 264 Query: 355 FV----------TAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDI 242 + T + ++WSAD + L +G D+ ++VW + Sbjct: 265 IIVDELRQDIITTNSKAEPPQCTSLAWSADGQTLFAGYTDNLIRVWQV 312 Score = 38.9 bits (89), Expect = 0.009 Identities = 25/79 (31%), Positives = 40/79 (50%), Gaps = 6/79 (7%) Frame = -2 Query: 340 RGHVADVYQISWSAD-SRLLLSGSKDSTLKVWDIRARKLKQDLP-----GHADEVYAVDW 179 +GH V QI+ + ++LS S+D T+ +W + + +P GH+ V V Sbjct: 12 KGHSGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVI 71 Query: 178 SPDGEKVVSGGKDRALKLW 122 S DG+ +SG D L+LW Sbjct: 72 SSDGQFALSGSWDGTLRLW 90
>UTP13_SCHPO (Q9USN3) Probable U3 small nucleolar RNA-associated protein 13 (U3| snoRNA-associated protein 13) Length = 777 Score = 88.2 bits (217), Expect = 1e-17 Identities = 43/113 (38%), Positives = 67/113 (59%) Frame = -2 Query: 460 HQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLL 281 H + VN + S DG+ +ASAS DK++KLW+ TG+ V RGH V+ S++ SR L Sbjct: 464 HDRDVNAIQVSKDGRIIASASQDKTIKLWDSSTGEVVGVLRGHRRGVWACSFNPFSRQLA 523 Query: 280 SGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 SGS D T+++W++ ++ Q L GH + + + G +VVS D +K+W Sbjct: 524 SGSGDRTIRIWNVDTQQCVQTLEGHTGAILKLIYISQGTQVVSAAADGLVKVW 576 Score = 66.2 bits (160), Expect = 5e-11 Identities = 46/154 (29%), Positives = 75/154 (48%), Gaps = 16/154 (10%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARM---TGHQKVVNHVYFSP---DGQ--WLASASFDKSVK 380 +G+ D T+ LW I + TGH V V P +G +LAS+S D+++K Sbjct: 381 TGAKDNTVRLWNLNIEDNVYKCIHVFTGHTASVTAVALGPLDVNGYPTFLASSSQDRTLK 440 Query: 379 LWN--------GITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLK 224 +N + + V + H DV I S D R++ S S+D T+K+WD ++ Sbjct: 441 RFNLGSQLNKSDFSNRAVWTIKAHDRDVNAIQVSKDGRIIASASQDKTIKLWDSSTGEVV 500 Query: 223 QDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 L GH V+A ++P ++ SG DR +++W Sbjct: 501 GVLRGHRRGVWACSFNPFSRQLASGSGDRTIRIW 534 Score = 60.8 bits (146), Expect = 2e-09 Identities = 40/133 (30%), Positives = 64/133 (48%), Gaps = 17/133 (12%) Frame = -2 Query: 469 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWN----GITGKFVTAFRGHVADVYQISW- 305 + GH +V + S DG WLA+ + D +V+LWN K + F GH A V ++ Sbjct: 360 LEGHTDIVLTLDSSEDGVWLATGAKDNTVRLWNLNIEDNVYKCIHVFTGHTASVTAVALG 419 Query: 304 ----SADSRLLLSGSKDSTLKVWDIRARKLKQD--------LPGHADEVYAVDWSPDGEK 161 + L S S+D TLK +++ ++ K D + H +V A+ S DG Sbjct: 420 PLDVNGYPTFLASSSQDRTLKRFNLGSQLNKSDFSNRAVWTIKAHDRDVNAIQVSKDGRI 479 Query: 160 VVSGGKDRALKLW 122 + S +D+ +KLW Sbjct: 480 IASASQDKTIKLW 492 Score = 60.5 bits (145), Expect = 3e-09 Identities = 36/132 (27%), Positives = 69/132 (52%), Gaps = 7/132 (5%) Frame = -2 Query: 496 TISKQPKAR----MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVT-AFRGH 332 TI + P R M H+ V + P LA+ + VK+W+ I G +VT +FRGH Sbjct: 86 TIYEIPSGRRIKSMKAHETPVITMTIDPTNTLLATGGAEGLVKVWD-IAGAYVTHSFRGH 144 Query: 331 VADVYQISWS--ADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKV 158 + + + ++ +L SG+ DS +++WD+ + + GH+ + + + P G + Sbjct: 145 GGVISALCFGKHQNTWVLASGADDSRVRLWDLNSSRSMAVFEGHSSVIRGLTFEPTGSFL 204 Query: 157 VSGGKDRALKLW 122 +SG +D+ +++W Sbjct: 205 LSGSRDKTVQVW 216 Score = 55.5 bits (132), Expect = 9e-08 Identities = 33/119 (27%), Positives = 61/119 (51%), Gaps = 5/119 (4%) Frame = -2 Query: 463 GHQKVVNHVYFSP-DGQW-LASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 290 GH V++ + F W LAS + D V+LW+ + + + F GH + + +++ Sbjct: 143 GHGGVISALCFGKHQNTWVLASGADDSRVRLWDLNSSRSMAVFEGHSSVIRGLTFEPTGS 202 Query: 289 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDW---SPDGEKVVSGGKDRALKLW 122 LLSGS+D T++VW+I+ R + +P V A+ W P+ + + + G+ + W Sbjct: 203 FLLSGSRDKTVQVWNIKKRSAVRTIPVF-HSVEAIGWVNGQPEEKILYTAGEGNLILAW 260 Score = 45.4 bits (106), Expect = 1e-04 Identities = 29/100 (29%), Positives = 47/100 (47%), Gaps = 3/100 (3%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SG+DD + LW+ S+ A GH V+ + F P G +L S S DK+V++WN I + Sbjct: 164 SGADDSRVRLWDLNSSRS-MAVFEGHSSVIRGLTFEPTGSFLLSGSRDKTVQVWN-IKKR 221 Query: 355 FVTAFRGHVADVYQISW---SADSRLLLSGSKDSTLKVWD 245 V I W + ++L + + + + WD Sbjct: 222 SAVRTIPVFHSVEAIGWVNGQPEEKILYTAGEGNLILAWD 261 Score = 38.5 bits (88), Expect = 0.012 Identities = 23/111 (20%), Positives = 49/111 (44%), Gaps = 2/111 (1%) Frame = -2 Query: 448 VNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSK 269 V + + D + L +A + + ++ +G+ + + + H V ++ + LL +G Sbjct: 64 VTALAITSDSKKLIAAFRSRLLTIYEIPSGRRIKSMKAHETPVITMTIDPTNTLLATGGA 123 Query: 268 DSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEK--VVSGGKDRALKLW 122 + +KVWDI + GH + A+ + + SG D ++LW Sbjct: 124 EGLVKVWDIAGAYVTHSFRGHGGVISALCFGKHQNTWVLASGADDSRVRLW 174
>GBLP_CHICK (P63247) Guanine nucleotide-binding protein beta subunit 2-like 1| (Guanine nucleotide-binding protein beta subunit-like protein 12.3) (Receptor of activated protein kinase C 1) (RACK1) (Receptor for activated C kinase) Length = 317 Score = 87.8 bits (216), Expect = 2e-17 Identities = 49/145 (33%), Positives = 82/145 (56%), Gaps = 7/145 (4%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQ----PKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNG 368 S S D T+ +W+ T + P+ + GH V+ V S DGQ+ S S+D +++LW+ Sbjct: 33 SASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDL 92 Query: 367 ITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD-IRARKLKQDLPGHADEVY 191 TG F GH DV +++S+D+R ++SGS+D T+K+W+ + K H++ V Sbjct: 93 TTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVS 152 Query: 190 AVDWSPDGEK--VVSGGKDRALKLW 122 V +SP+ +VS G D+ +K+W Sbjct: 153 CVRFSPNSSNPIIVSCGWDKLVKVW 177 Score = 56.2 bits (134), Expect = 6e-08 Identities = 40/124 (32%), Positives = 58/124 (46%), Gaps = 2/124 (1%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQ--WLASASFDKSVKLWNGIT 362 SGS D T+ LW + + H + V+ V FSP+ + S +DK VK+WN Sbjct: 122 SGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLAN 181 Query: 361 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 182 K T GH + ++ S D L SG KD +WD+ K L G D + A+ Sbjct: 182 CKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDG-GDIINALC 240 Query: 181 WSPD 170 +SP+ Sbjct: 241 FSPN 244 Score = 52.4 bits (124), Expect = 8e-07 Identities = 33/128 (25%), Positives = 57/128 (44%), Gaps = 9/128 (7%) Frame = -2 Query: 478 KARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSA 299 K GH +N V SPDG AS D LW+ GK + G D+ + Sbjct: 185 KTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDG--GDIINALCFS 242 Query: 298 DSRLLLSGSKDSTLKVWDIRAR----KLKQDL-----PGHADEVYAVDWSPDGEKVVSGG 146 +R L + ++K+WD+ + +LKQ++ + ++ WS DG+ + +G Sbjct: 243 PNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGY 302 Query: 145 KDRALKLW 122 D +++W Sbjct: 303 TDNLVRVW 310 Score = 46.2 bits (108), Expect = 6e-05 Identities = 29/108 (26%), Positives = 51/108 (47%), Gaps = 10/108 (9%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SG D LW+ K G ++N + FSP+ WL +A+ S+K+W+ + GK Sbjct: 209 SGGKDGQAMLWDLNEGKHLYTLDGGD--IINALCFSPNRYWLCAAT-GPSIKIWD-LEGK 264 Query: 355 FV----------TAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDI 242 + T+ + ++WSAD + L +G D+ ++VW + Sbjct: 265 IIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQV 312 Score = 38.5 bits (88), Expect = 0.012 Identities = 25/79 (31%), Positives = 40/79 (50%), Gaps = 6/79 (7%) Frame = -2 Query: 340 RGHVADVYQISWSAD-SRLLLSGSKDSTLKVWDIRARKLKQDLP-----GHADEVYAVDW 179 +GH V QI+ + ++LS S+D T+ +W + + +P GH+ V V Sbjct: 12 KGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVI 71 Query: 178 SPDGEKVVSGGKDRALKLW 122 S DG+ +SG D L+LW Sbjct: 72 SSDGQFALSGSWDGTLRLW 90
>GBLP_RAT (P63245) Guanine nucleotide-binding protein beta subunit 2-like 1| (Receptor of activated protein kinase C 1) (RACK1) (Receptor for activated C kinase) Length = 316 Score = 87.8 bits (216), Expect = 2e-17 Identities = 49/145 (33%), Positives = 82/145 (56%), Gaps = 7/145 (4%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQ----PKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNG 368 S S D T+ +W+ T + P+ + GH V+ V S DGQ+ S S+D +++LW+ Sbjct: 32 SASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDL 91 Query: 367 ITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD-IRARKLKQDLPGHADEVY 191 TG F GH DV +++S+D+R ++SGS+D T+K+W+ + K H++ V Sbjct: 92 TTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVS 151 Query: 190 AVDWSPDGEK--VVSGGKDRALKLW 122 V +SP+ +VS G D+ +K+W Sbjct: 152 CVRFSPNSSNPIIVSCGWDKLVKVW 176 Score = 56.2 bits (134), Expect = 6e-08 Identities = 40/124 (32%), Positives = 58/124 (46%), Gaps = 2/124 (1%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQ--WLASASFDKSVKLWNGIT 362 SGS D T+ LW + + H + V+ V FSP+ + S +DK VK+WN Sbjct: 121 SGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLAN 180 Query: 361 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 182 K T GH + ++ S D L SG KD +WD+ K L G D + A+ Sbjct: 181 CKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDG-GDIINALC 239 Query: 181 WSPD 170 +SP+ Sbjct: 240 FSPN 243 Score = 52.4 bits (124), Expect = 8e-07 Identities = 33/128 (25%), Positives = 57/128 (44%), Gaps = 9/128 (7%) Frame = -2 Query: 478 KARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSA 299 K GH +N V SPDG AS D LW+ GK + G D+ + Sbjct: 184 KTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDG--GDIINALCFS 241 Query: 298 DSRLLLSGSKDSTLKVWDIRAR----KLKQDL-----PGHADEVYAVDWSPDGEKVVSGG 146 +R L + ++K+WD+ + +LKQ++ + ++ WS DG+ + +G Sbjct: 242 PNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGY 301 Query: 145 KDRALKLW 122 D +++W Sbjct: 302 TDNLVRVW 309 Score = 46.2 bits (108), Expect = 6e-05 Identities = 29/108 (26%), Positives = 51/108 (47%), Gaps = 10/108 (9%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SG D LW+ K G ++N + FSP+ WL +A+ S+K+W+ + GK Sbjct: 208 SGGKDGQAMLWDLNEGKHLYTLDGGD--IINALCFSPNRYWLCAAT-GPSIKIWD-LEGK 263 Query: 355 FV----------TAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDI 242 + T+ + ++WSAD + L +G D+ ++VW + Sbjct: 264 IIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQV 311 Score = 38.5 bits (88), Expect = 0.012 Identities = 25/79 (31%), Positives = 40/79 (50%), Gaps = 6/79 (7%) Frame = -2 Query: 340 RGHVADVYQISWSAD-SRLLLSGSKDSTLKVWDIRARKLKQDLP-----GHADEVYAVDW 179 +GH V QI+ + ++LS S+D T+ +W + + +P GH+ V V Sbjct: 11 KGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVI 70 Query: 178 SPDGEKVVSGGKDRALKLW 122 S DG+ +SG D L+LW Sbjct: 71 SSDGQFALSGSWDGTLRLW 89
>GBLP_PIG (P63246) Guanine nucleotide-binding protein beta subunit 2-like 1| (Receptor of activated protein kinase C 1) (RACK1) (Receptor for activated C kinase) Length = 316 Score = 87.8 bits (216), Expect = 2e-17 Identities = 49/145 (33%), Positives = 82/145 (56%), Gaps = 7/145 (4%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQ----PKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNG 368 S S D T+ +W+ T + P+ + GH V+ V S DGQ+ S S+D +++LW+ Sbjct: 32 SASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDL 91 Query: 367 ITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD-IRARKLKQDLPGHADEVY 191 TG F GH DV +++S+D+R ++SGS+D T+K+W+ + K H++ V Sbjct: 92 TTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVS 151 Query: 190 AVDWSPDGEK--VVSGGKDRALKLW 122 V +SP+ +VS G D+ +K+W Sbjct: 152 CVRFSPNSSNPIIVSCGWDKLVKVW 176 Score = 56.2 bits (134), Expect = 6e-08 Identities = 40/124 (32%), Positives = 58/124 (46%), Gaps = 2/124 (1%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQ--WLASASFDKSVKLWNGIT 362 SGS D T+ LW + + H + V+ V FSP+ + S +DK VK+WN Sbjct: 121 SGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLAN 180 Query: 361 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 182 K T GH + ++ S D L SG KD +WD+ K L G D + A+ Sbjct: 181 CKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDG-GDIINALC 239 Query: 181 WSPD 170 +SP+ Sbjct: 240 FSPN 243 Score = 52.4 bits (124), Expect = 8e-07 Identities = 33/128 (25%), Positives = 57/128 (44%), Gaps = 9/128 (7%) Frame = -2 Query: 478 KARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSA 299 K GH +N V SPDG AS D LW+ GK + G D+ + Sbjct: 184 KTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDG--GDIINALCFS 241 Query: 298 DSRLLLSGSKDSTLKVWDIRAR----KLKQDL-----PGHADEVYAVDWSPDGEKVVSGG 146 +R L + ++K+WD+ + +LKQ++ + ++ WS DG+ + +G Sbjct: 242 PNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGY 301 Query: 145 KDRALKLW 122 D +++W Sbjct: 302 TDNLVRVW 309 Score = 46.2 bits (108), Expect = 6e-05 Identities = 29/108 (26%), Positives = 51/108 (47%), Gaps = 10/108 (9%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SG D LW+ K G ++N + FSP+ WL +A+ S+K+W+ + GK Sbjct: 208 SGGKDGQAMLWDLNEGKHLYTLDGGD--IINALCFSPNRYWLCAAT-GPSIKIWD-LEGK 263 Query: 355 FV----------TAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDI 242 + T+ + ++WSAD + L +G D+ ++VW + Sbjct: 264 IIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQV 311 Score = 38.5 bits (88), Expect = 0.012 Identities = 25/79 (31%), Positives = 40/79 (50%), Gaps = 6/79 (7%) Frame = -2 Query: 340 RGHVADVYQISWSAD-SRLLLSGSKDSTLKVWDIRARKLKQDLP-----GHADEVYAVDW 179 +GH V QI+ + ++LS S+D T+ +W + + +P GH+ V V Sbjct: 11 KGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVI 70 Query: 178 SPDGEKVVSGGKDRALKLW 122 S DG+ +SG D L+LW Sbjct: 71 SSDGQFALSGSWDGTLRLW 89
>GBLP_MOUSE (P68040) Guanine nucleotide-binding protein beta subunit 2-like 1| (Receptor of activated protein kinase C 1) (RACK1) (Receptor for activated C kinase) (p205) (12-3) Length = 316 Score = 87.8 bits (216), Expect = 2e-17 Identities = 49/145 (33%), Positives = 82/145 (56%), Gaps = 7/145 (4%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQ----PKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNG 368 S S D T+ +W+ T + P+ + GH V+ V S DGQ+ S S+D +++LW+ Sbjct: 32 SASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDL 91 Query: 367 ITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD-IRARKLKQDLPGHADEVY 191 TG F GH DV +++S+D+R ++SGS+D T+K+W+ + K H++ V Sbjct: 92 TTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVS 151 Query: 190 AVDWSPDGEK--VVSGGKDRALKLW 122 V +SP+ +VS G D+ +K+W Sbjct: 152 CVRFSPNSSNPIIVSCGWDKLVKVW 176 Score = 56.2 bits (134), Expect = 6e-08 Identities = 40/124 (32%), Positives = 58/124 (46%), Gaps = 2/124 (1%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQ--WLASASFDKSVKLWNGIT 362 SGS D T+ LW + + H + V+ V FSP+ + S +DK VK+WN Sbjct: 121 SGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLAN 180 Query: 361 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 182 K T GH + ++ S D L SG KD +WD+ K L G D + A+ Sbjct: 181 CKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDG-GDIINALC 239 Query: 181 WSPD 170 +SP+ Sbjct: 240 FSPN 243 Score = 52.4 bits (124), Expect = 8e-07 Identities = 33/128 (25%), Positives = 57/128 (44%), Gaps = 9/128 (7%) Frame = -2 Query: 478 KARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSA 299 K GH +N V SPDG AS D LW+ GK + G D+ + Sbjct: 184 KTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDG--GDIINALCFS 241 Query: 298 DSRLLLSGSKDSTLKVWDIRAR----KLKQDL-----PGHADEVYAVDWSPDGEKVVSGG 146 +R L + ++K+WD+ + +LKQ++ + ++ WS DG+ + +G Sbjct: 242 PNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGY 301 Query: 145 KDRALKLW 122 D +++W Sbjct: 302 TDNLVRVW 309 Score = 46.2 bits (108), Expect = 6e-05 Identities = 29/108 (26%), Positives = 51/108 (47%), Gaps = 10/108 (9%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SG D LW+ K G ++N + FSP+ WL +A+ S+K+W+ + GK Sbjct: 208 SGGKDGQAMLWDLNEGKHLYTLDGGD--IINALCFSPNRYWLCAAT-GPSIKIWD-LEGK 263 Query: 355 FV----------TAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDI 242 + T+ + ++WSAD + L +G D+ ++VW + Sbjct: 264 IIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQV 311 Score = 38.5 bits (88), Expect = 0.012 Identities = 25/79 (31%), Positives = 40/79 (50%), Gaps = 6/79 (7%) Frame = -2 Query: 340 RGHVADVYQISWSAD-SRLLLSGSKDSTLKVWDIRARKLKQDLP-----GHADEVYAVDW 179 +GH V QI+ + ++LS S+D T+ +W + + +P GH+ V V Sbjct: 11 KGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVI 70 Query: 178 SPDGEKVVSGGKDRALKLW 122 S DG+ +SG D L+LW Sbjct: 71 SSDGQFALSGSWDGTLRLW 89
>GBLP_MACFA (Q4R7Y4) Guanine nucleotide-binding protein beta subunit 2-like 1| Length = 316 Score = 87.8 bits (216), Expect = 2e-17 Identities = 49/145 (33%), Positives = 82/145 (56%), Gaps = 7/145 (4%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQ----PKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNG 368 S S D T+ +W+ T + P+ + GH V+ V S DGQ+ S S+D +++LW+ Sbjct: 32 SASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDL 91 Query: 367 ITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD-IRARKLKQDLPGHADEVY 191 TG F GH DV +++S+D+R ++SGS+D T+K+W+ + K H++ V Sbjct: 92 TTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVS 151 Query: 190 AVDWSPDGEK--VVSGGKDRALKLW 122 V +SP+ +VS G D+ +K+W Sbjct: 152 CVRFSPNSSNPIIVSCGWDKLVKVW 176 Score = 56.2 bits (134), Expect = 6e-08 Identities = 40/124 (32%), Positives = 58/124 (46%), Gaps = 2/124 (1%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQ--WLASASFDKSVKLWNGIT 362 SGS D T+ LW + + H + V+ V FSP+ + S +DK VK+WN Sbjct: 121 SGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLAN 180 Query: 361 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 182 K T GH + ++ S D L SG KD +WD+ K L G D + A+ Sbjct: 181 CKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDG-GDIINALC 239 Query: 181 WSPD 170 +SP+ Sbjct: 240 FSPN 243 Score = 52.4 bits (124), Expect = 8e-07 Identities = 33/128 (25%), Positives = 57/128 (44%), Gaps = 9/128 (7%) Frame = -2 Query: 478 KARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSA 299 K GH +N V SPDG AS D LW+ GK + G D+ + Sbjct: 184 KTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDG--GDIINALCFS 241 Query: 298 DSRLLLSGSKDSTLKVWDIRAR----KLKQDL-----PGHADEVYAVDWSPDGEKVVSGG 146 +R L + ++K+WD+ + +LKQ++ + ++ WS DG+ + +G Sbjct: 242 PNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGY 301 Query: 145 KDRALKLW 122 D +++W Sbjct: 302 TDNLVRVW 309 Score = 46.2 bits (108), Expect = 6e-05 Identities = 29/108 (26%), Positives = 51/108 (47%), Gaps = 10/108 (9%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SG D LW+ K G ++N + FSP+ WL +A+ S+K+W+ + GK Sbjct: 208 SGGKDGQAMLWDLNEGKHLYTLDGGD--IINALCFSPNRYWLCAAT-GPSIKIWD-LEGK 263 Query: 355 FV----------TAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDI 242 + T+ + ++WSAD + L +G D+ ++VW + Sbjct: 264 IIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQV 311 Score = 38.5 bits (88), Expect = 0.012 Identities = 25/79 (31%), Positives = 40/79 (50%), Gaps = 6/79 (7%) Frame = -2 Query: 340 RGHVADVYQISWSAD-SRLLLSGSKDSTLKVWDIRARKLKQDLP-----GHADEVYAVDW 179 +GH V QI+ + ++LS S+D T+ +W + + +P GH+ V V Sbjct: 11 KGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVI 70 Query: 178 SPDGEKVVSGGKDRALKLW 122 S DG+ +SG D L+LW Sbjct: 71 SSDGQFALSGSWDGTLRLW 89
>GBLP_HUMAN (P63244) Guanine nucleotide-binding protein beta subunit 2-like 1| (Guanine nucleotide-binding protein beta subunit-like protein 12.3) (Receptor of activated protein kinase C 1) (RACK1) (Receptor for activated C kinase) Length = 316 Score = 87.8 bits (216), Expect = 2e-17 Identities = 49/145 (33%), Positives = 82/145 (56%), Gaps = 7/145 (4%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQ----PKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNG 368 S S D T+ +W+ T + P+ + GH V+ V S DGQ+ S S+D +++LW+ Sbjct: 32 SASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDL 91 Query: 367 ITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD-IRARKLKQDLPGHADEVY 191 TG F GH DV +++S+D+R ++SGS+D T+K+W+ + K H++ V Sbjct: 92 TTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVS 151 Query: 190 AVDWSPDGEK--VVSGGKDRALKLW 122 V +SP+ +VS G D+ +K+W Sbjct: 152 CVRFSPNSSNPIIVSCGWDKLVKVW 176 Score = 56.2 bits (134), Expect = 6e-08 Identities = 40/124 (32%), Positives = 58/124 (46%), Gaps = 2/124 (1%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQ--WLASASFDKSVKLWNGIT 362 SGS D T+ LW + + H + V+ V FSP+ + S +DK VK+WN Sbjct: 121 SGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLAN 180 Query: 361 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 182 K T GH + ++ S D L SG KD +WD+ K L G D + A+ Sbjct: 181 CKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDG-GDIINALC 239 Query: 181 WSPD 170 +SP+ Sbjct: 240 FSPN 243 Score = 52.4 bits (124), Expect = 8e-07 Identities = 33/128 (25%), Positives = 57/128 (44%), Gaps = 9/128 (7%) Frame = -2 Query: 478 KARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSA 299 K GH +N V SPDG AS D LW+ GK + G D+ + Sbjct: 184 KTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDG--GDIINALCFS 241 Query: 298 DSRLLLSGSKDSTLKVWDIRAR----KLKQDL-----PGHADEVYAVDWSPDGEKVVSGG 146 +R L + ++K+WD+ + +LKQ++ + ++ WS DG+ + +G Sbjct: 242 PNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGY 301 Query: 145 KDRALKLW 122 D +++W Sbjct: 302 TDNLVRVW 309 Score = 46.2 bits (108), Expect = 6e-05 Identities = 29/108 (26%), Positives = 51/108 (47%), Gaps = 10/108 (9%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SG D LW+ K G ++N + FSP+ WL +A+ S+K+W+ + GK Sbjct: 208 SGGKDGQAMLWDLNEGKHLYTLDGGD--IINALCFSPNRYWLCAAT-GPSIKIWD-LEGK 263 Query: 355 FV----------TAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDI 242 + T+ + ++WSAD + L +G D+ ++VW + Sbjct: 264 IIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQV 311 Score = 38.5 bits (88), Expect = 0.012 Identities = 25/79 (31%), Positives = 40/79 (50%), Gaps = 6/79 (7%) Frame = -2 Query: 340 RGHVADVYQISWSAD-SRLLLSGSKDSTLKVWDIRARKLKQDLP-----GHADEVYAVDW 179 +GH V QI+ + ++LS S+D T+ +W + + +P GH+ V V Sbjct: 11 KGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVI 70 Query: 178 SPDGEKVVSGGKDRALKLW 122 S DG+ +SG D L+LW Sbjct: 71 SSDGQFALSGSWDGTLRLW 89
>GBLP_BOVIN (P63243) Guanine nucleotide-binding protein beta subunit 2-like 1| (Receptor of activated protein kinase C 1) (RACK1) (Receptor for activated C kinase) Length = 316 Score = 87.8 bits (216), Expect = 2e-17 Identities = 49/145 (33%), Positives = 82/145 (56%), Gaps = 7/145 (4%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQ----PKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNG 368 S S D T+ +W+ T + P+ + GH V+ V S DGQ+ S S+D +++LW+ Sbjct: 32 SASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDL 91 Query: 367 ITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD-IRARKLKQDLPGHADEVY 191 TG F GH DV +++S+D+R ++SGS+D T+K+W+ + K H++ V Sbjct: 92 TTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVS 151 Query: 190 AVDWSPDGEK--VVSGGKDRALKLW 122 V +SP+ +VS G D+ +K+W Sbjct: 152 CVRFSPNSSNPIIVSCGWDKLVKVW 176 Score = 56.2 bits (134), Expect = 6e-08 Identities = 40/124 (32%), Positives = 58/124 (46%), Gaps = 2/124 (1%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQ--WLASASFDKSVKLWNGIT 362 SGS D T+ LW + + H + V+ V FSP+ + S +DK VK+WN Sbjct: 121 SGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLAN 180 Query: 361 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 182 K T GH + ++ S D L SG KD +WD+ K L G D + A+ Sbjct: 181 CKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDG-GDIINALC 239 Query: 181 WSPD 170 +SP+ Sbjct: 240 FSPN 243 Score = 52.4 bits (124), Expect = 8e-07 Identities = 33/128 (25%), Positives = 57/128 (44%), Gaps = 9/128 (7%) Frame = -2 Query: 478 KARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSA 299 K GH +N V SPDG AS D LW+ GK + G D+ + Sbjct: 184 KTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDG--GDIINALCFS 241 Query: 298 DSRLLLSGSKDSTLKVWDIRAR----KLKQDL-----PGHADEVYAVDWSPDGEKVVSGG 146 +R L + ++K+WD+ + +LKQ++ + ++ WS DG+ + +G Sbjct: 242 PNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGY 301 Query: 145 KDRALKLW 122 D +++W Sbjct: 302 TDNLVRVW 309 Score = 46.2 bits (108), Expect = 6e-05 Identities = 29/108 (26%), Positives = 51/108 (47%), Gaps = 10/108 (9%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SG D LW+ K G ++N + FSP+ WL +A+ S+K+W+ + GK Sbjct: 208 SGGKDGQAMLWDLNEGKHLYTLDGGD--IINALCFSPNRYWLCAAT-GPSIKIWD-LEGK 263 Query: 355 FV----------TAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDI 242 + T+ + ++WSAD + L +G D+ ++VW + Sbjct: 264 IIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQV 311 Score = 38.5 bits (88), Expect = 0.012 Identities = 25/79 (31%), Positives = 40/79 (50%), Gaps = 6/79 (7%) Frame = -2 Query: 340 RGHVADVYQISWSAD-SRLLLSGSKDSTLKVWDIRARKLKQDLP-----GHADEVYAVDW 179 +GH V QI+ + ++LS S+D T+ +W + + +P GH+ V V Sbjct: 11 KGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVI 70 Query: 178 SPDGEKVVSGGKDRALKLW 122 S DG+ +SG D L+LW Sbjct: 71 SSDGQFALSGSWDGTLRLW 89
>GBLP_BIOGL (Q93134) Guanine nucleotide-binding protein beta subunit 2-like 1| (Receptor of activated protein kinase C) (RACK) Length = 316 Score = 87.4 bits (215), Expect = 2e-17 Identities = 50/145 (34%), Positives = 81/145 (55%), Gaps = 7/145 (4%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQ----PKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNG 368 S S D ++ +W T + P+ + GH V+ V S DGQ+ S S+D +++LW+ Sbjct: 33 SASRDKSLIVWRLTRDESSYGVPQKSLHGHGHFVSDVILSSDGQFALSGSWDHTLRLWDL 92 Query: 367 ITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD-IRARKLKQDLPGHADEVY 191 TG+ F GH DV +++SAD+R ++SGS+D T+K+W+ + K H D Sbjct: 93 STGQTTRRFVGHTKDVLSVAFSADNRQIVSGSRDKTIKLWNTLGVCKYTIQDDCHTDWTS 152 Query: 190 AVDWSPDGEK--VVSGGKDRALKLW 122 V +SP+ + +VS G DR +K+W Sbjct: 153 CVRFSPNTQNPIIVSSGWDRLVKVW 177 Score = 60.1 bits (144), Expect = 4e-09 Identities = 41/124 (33%), Positives = 59/124 (47%), Gaps = 2/124 (1%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQ--WLASASFDKSVKLWNGIT 362 SGS D T+ LW + + H + V FSP+ Q + S+ +D+ VK+WN Sbjct: 122 SGSRDKTIKLWNTLGVCKYTIQDDCHTDWTSCVRFSPNTQNPIIVSSGWDRLVKVWNLTN 181 Query: 361 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 182 K T GH V ++ S D L SG KDS +WD+ K L G D + A+ Sbjct: 182 CKLKTNHYGHTGYVNTVTVSPDGSLCASGGKDSQAMLWDLNEGKHLYTLDGAGDTINALC 241 Query: 181 WSPD 170 +SP+ Sbjct: 242 FSPN 245 Score = 55.1 bits (131), Expect = 1e-07 Identities = 38/136 (27%), Positives = 61/136 (44%), Gaps = 7/136 (5%) Frame = -2 Query: 508 LWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHV 329 +W T K K GH VN V SPDG AS D LW+ GK + G Sbjct: 176 VWNLTNCKL-KTNHYGHTGYVNTVTVSPDGSLCASGGKDSQAMLWDLNEGKHLYTLDG-A 233 Query: 328 ADVYQISWSADSRLLLSGSKDSTLKVWDIRAR----KLKQDLPG---HADEVYAVDWSPD 170 D + +R L + ++K+WD+ + +LK ++ G A ++ WS D Sbjct: 234 GDTINALCFSPNRYWLCVASGPSIKIWDLEGKVVVDELKPEVMGTTSKAPTCLSLAWSAD 293 Query: 169 GEKVVSGGKDRALKLW 122 G+ + +G D+ +++W Sbjct: 294 GQTLFAGYTDKLIRVW 309 Score = 45.1 bits (105), Expect = 1e-04 Identities = 30/106 (28%), Positives = 46/106 (43%), Gaps = 8/106 (7%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SG D LW+ K + G +N + FSP+ WL AS S+K+W+ + GK Sbjct: 209 SGGKDSQAMLWDLNEGKHLYT-LDGAGDTINALCFSPNRYWLCVAS-GPSIKIWD-LEGK 265 Query: 355 FVT--------AFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDI 242 V ++WSAD + L +G D ++VW + Sbjct: 266 VVVDELKPEVMGTTSKAPTCLSLAWSADGQTLFAGYTDKLIRVWQV 311 Score = 38.1 bits (87), Expect = 0.016 Identities = 26/79 (32%), Positives = 39/79 (49%), Gaps = 6/79 (7%) Frame = -2 Query: 340 RGHVADVYQISWSAD-SRLLLSGSKDSTLKVWDIRARKLKQDLP-----GHADEVYAVDW 179 +GH V QI+ + ++LS S+D +L VW + + +P GH V V Sbjct: 12 QGHGGWVTQIATTPQYPDMILSASRDKSLIVWRLTRDESSYGVPQKSLHGHGHFVSDVIL 71 Query: 178 SPDGEKVVSGGKDRALKLW 122 S DG+ +SG D L+LW Sbjct: 72 SSDGQFALSGSWDHTLRLW 90
>PRP46_YARLI (Q6C709) Pre-mRNA-splicing factor PRP46 (Pre-mRNA-processing| protein 46) Length = 472 Score = 87.4 bits (215), Expect = 2e-17 Identities = 40/116 (34%), Positives = 62/116 (53%) Frame = -2 Query: 469 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 290 +TGHQ V V P+ QW A+ S DK++K+W+ TGK GH+ V + S Sbjct: 159 ITGHQGWVRSVCVEPENQWFATGSADKTIKIWDLATGKLRLTLTGHIMGVRALGVSPRHP 218 Query: 289 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 + SG +D +K WD+ K+ + GH VY++D P + +VS G+D ++W Sbjct: 219 YMFSGGEDKMVKCWDLETNKVVRHYHGHLSAVYSLDIHPTLDVLVSAGRDAVARVW 274 Score = 75.1 bits (183), Expect = 1e-13 Identities = 42/138 (30%), Positives = 68/138 (49%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 +GS D T+ +W+ K + +TGH V + SP ++ S DK VK W+ T K Sbjct: 180 TGSADKTIKIWDLATGKL-RLTLTGHIMGVRALGVSPRHPYMFSGGEDKMVKCWDLETNK 238 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 V + GH++ VY + +L+S +D+ +VWDIR R L GH + V + Sbjct: 239 VVRHYHGHLSAVYSLDIHPTLDVLVSAGRDAVARVWDIRTRDPVVVLSGHKSTINRVKFQ 298 Query: 175 PDGEKVVSGGKDRALKLW 122 +V++ D ++LW Sbjct: 299 ASEPQVITASADETVRLW 316 Score = 48.1 bits (113), Expect = 2e-05 Identities = 33/138 (23%), Positives = 59/138 (42%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SG +D + W+ +K + GH V + P L SA D ++W+ T Sbjct: 222 SGGEDKMVKCWDLETNKVVR-HYHGHLSAVYSLDIHPTLDVLVSAGRDAVARVWDIRTRD 280 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 V GH + + ++ + A +++ S D T+++W+++A K L H V + Sbjct: 281 PVVVLSGHKSTINRVKFQASEPQVITASADETVRLWNLQAGKTMTTLTHHKKSVRGLTLH 340 Query: 175 PDGEKVVSGGKDRALKLW 122 P+ E S + K W Sbjct: 341 PE-EFTFSTASANSSKQW 357
>GBLP_ORENI (O42249) Guanine nucleotide-binding protein beta subunit 2-like 1| (Receptor of activated protein kinase C) (RACK) Length = 317 Score = 87.4 bits (215), Expect = 2e-17 Identities = 49/145 (33%), Positives = 82/145 (56%), Gaps = 7/145 (4%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQ----PKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNG 368 S S D ++ +W+ T + P+ + GH V+ V S DGQ+ S ++D +++LW+ Sbjct: 33 SASRDKSIIMWKLTRDETNYGIPQRSLKGHSHFVSDVVISSDGQFALSGAWDGTLRLWDL 92 Query: 367 ITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD-IRARKLKQDLPGHADEVY 191 TG F GH DV +++SAD+R ++SGS+D T+K+W+ + K GH + V Sbjct: 93 TTGLTTRRFVGHTKDVLSVAFSADNRQIVSGSRDKTIKLWNTLGVCKYTIQDEGHTEWVS 152 Query: 190 AVDWSPDGEK--VVSGGKDRALKLW 122 V +SP+ +VS G D+ +K+W Sbjct: 153 CVRFSPNSSNPIIVSCGWDKMVKVW 177 Score = 56.2 bits (134), Expect = 6e-08 Identities = 40/124 (32%), Positives = 58/124 (46%), Gaps = 2/124 (1%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQ--WLASASFDKSVKLWNGIT 362 SGS D T+ LW + + GH + V+ V FSP+ + S +DK VK+WN Sbjct: 122 SGSRDKTIKLWNTLGVCKYTIQDEGHTEWVSCVRFSPNSSNPIIVSCGWDKMVKVWNLAN 181 Query: 361 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 182 K T GH + ++ S D L SG KD +WD+ K L D + A+ Sbjct: 182 CKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDS-GDVINALC 240 Query: 181 WSPD 170 +SP+ Sbjct: 241 FSPN 244 Score = 47.0 bits (110), Expect = 3e-05 Identities = 30/108 (27%), Positives = 51/108 (47%), Gaps = 10/108 (9%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SG D LW+ K +G V+N + FSP+ WL +A+ S+K+W+ + GK Sbjct: 209 SGGKDGQAMLWDLNEGKHLYTLDSGD--VINALCFSPNRYWLCAAT-GPSIKIWD-LEGK 264 Query: 355 FV----------TAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDI 242 + T + ++WSAD + L +G D+ ++VW + Sbjct: 265 IIVDELRQEVISTNSKAEPPQCTSLAWSADGQTLFAGYTDNLIRVWQV 312
>GBLP_SOYBN (Q39836) Guanine nucleotide-binding protein beta subunit-like| protein Length = 325 Score = 87.0 bits (214), Expect = 3e-17 Identities = 50/146 (34%), Positives = 77/146 (52%), Gaps = 8/146 (5%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQ----PKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNG 368 + S D ++ LW T + P+ R+TGH V V S DGQ+ S S+D ++LW+ Sbjct: 33 TASRDRSIILWHLTKEDKTYGVPRRRLTGHSHFVQDVVLSSDGQFALSGSWDGELRLWDL 92 Query: 367 ITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDI--RARKLKQDLPGHADEV 194 G F GH DV +++S D+R ++S S+D T+K+W+ + QD H+D V Sbjct: 93 AAGTSARRFVGHTKDVLSVAFSIDNRQIVSASRDRTIKLWNTLGECKYTIQDGDAHSDWV 152 Query: 193 YAVDWSPD--GEKVVSGGKDRALKLW 122 V +SP +VS DR +K+W Sbjct: 153 SCVRFSPSTLQPTIVSASWDRTVKVW 178 Score = 57.4 bits (137), Expect = 2e-08 Identities = 42/156 (26%), Positives = 72/156 (46%), Gaps = 18/156 (11%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 S S D T+ +W T K + + GH VN V SPDG AS D + LW+ GK Sbjct: 168 SASWDRTVKVWNLTNCKL-RNTLAGHNGYVNTVAVSPDGSLCASGGKDGVILLWDLAEGK 226 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLP------------ 212 + + + + SR L + + ++K+WD+ ++ + +DL Sbjct: 227 RLYSL--DAGSIIHALCFSPSRYWLCAATEQSIKIWDLESKSIVEDLKVDLKTEADATSG 284 Query: 211 -GHADE---VY--AVDWSPDGEKVVSGGKDRALKLW 122 G+A++ +Y +++WS DG + SG D ++W Sbjct: 285 GGNANKKKVIYCTSLNWSADGSTLFSGYTDGVARVW 320 Score = 53.5 bits (127), Expect = 4e-07 Identities = 42/142 (29%), Positives = 66/142 (46%), Gaps = 4/142 (2%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTG--HQKVVNHVYFSPDG--QWLASASFDKSVKLWNG 368 S S D T+ LW T+ + G H V+ V FSP + SAS+D++VK+WN Sbjct: 122 SASRDRTIKLWN-TLGECKYTIQDGDAHSDWVSCVRFSPSTLQPTIVSASWDRTVKVWNL 180 Query: 367 ITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYA 188 K GH V ++ S D L SG KD + +WD+ K L ++A Sbjct: 181 TNCKLRNTLAGHNGYVNTVAVSPDGSLCASGGKDGVILLWDLAEGKRLYSLDA-GSIIHA 239 Query: 187 VDWSPDGEKVVSGGKDRALKLW 122 + +SP + ++++K+W Sbjct: 240 LCFSP-SRYWLCAATEQSIKIW 260 Score = 41.2 bits (95), Expect = 0.002 Identities = 30/116 (25%), Positives = 50/116 (43%), Gaps = 18/116 (15%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SG D + LW+ K+ + G +++ + FSP WL +A+ ++S+K+W+ + Sbjct: 210 SGGKDGVILLWDLAEGKRLYSLDAG--SIIHALCFSPSRYWLCAAT-EQSIKIWDLESKS 266 Query: 355 FV------------------TAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDI 242 V A + V ++WSAD L SG D +VW I Sbjct: 267 IVEDLKVDLKTEADATSGGGNANKKKVIYCTSLNWSADGSTLFSGYTDGVARVWAI 322
>GBLP_MEDSA (O24076) Guanine nucleotide-binding protein beta subunit-like| protein Length = 325 Score = 87.0 bits (214), Expect = 3e-17 Identities = 50/146 (34%), Positives = 78/146 (53%), Gaps = 8/146 (5%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQ----PKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNG 368 + S D ++ LW T + P+ R+TGH V V S DGQ+ S S+D ++LW+ Sbjct: 33 TASRDKSIILWHLTKEDKTYGVPRRRLTGHSHFVQDVVLSSDGQFALSGSWDGELRLWDL 92 Query: 367 ITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDI--RARKLKQDLPGHADEV 194 G F GH DV +++S D+R ++S S+D T+K+W+ + QD H+D V Sbjct: 93 NAGTSARRFVGHTKDVLSVAFSIDNRQIVSASRDRTIKLWNTLGECKYTIQDGDAHSDWV 152 Query: 193 YAVDWSPDGEK--VVSGGKDRALKLW 122 V +SP + +VS DR +K+W Sbjct: 153 SCVRFSPSTPQPTIVSASWDRTVKVW 178 Score = 58.2 bits (139), Expect = 1e-08 Identities = 43/156 (27%), Positives = 69/156 (44%), Gaps = 18/156 (11%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 S S D T+ +W T K + + GH VN V SPDG AS D + LW+ GK Sbjct: 168 SASWDRTVKVWNLTNCKL-RNTLAGHSGYVNTVAVSPDGSLCASGGKDGVILLWDLAEGK 226 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARK----LKQDLPGHADEVY- 191 + + + + +R L + +S++K+WD+ ++ LK DL AD Sbjct: 227 RLYSL--DAGSIIHALCFSPNRYWLCAATESSIKIWDLESKSIVEDLKVDLKTEADAAIG 284 Query: 190 -------------AVDWSPDGEKVVSGGKDRALKLW 122 +++WS DG + SG D +++W Sbjct: 285 GDTTTKKKVIYCTSLNWSADGSTLFSGYTDGVVRVW 320 Score = 53.5 bits (127), Expect = 4e-07 Identities = 42/142 (29%), Positives = 66/142 (46%), Gaps = 4/142 (2%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTG--HQKVVNHVYFSPDGQW--LASASFDKSVKLWNG 368 S S D T+ LW T+ + G H V+ V FSP + SAS+D++VK+WN Sbjct: 122 SASRDRTIKLWN-TLGECKYTIQDGDAHSDWVSCVRFSPSTPQPTIVSASWDRTVKVWNL 180 Query: 367 ITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYA 188 K GH V ++ S D L SG KD + +WD+ K L ++A Sbjct: 181 TNCKLRNTLAGHSGYVNTVAVSPDGSLCASGGKDGVILLWDLAEGKRLYSLDA-GSIIHA 239 Query: 187 VDWSPDGEKVVSGGKDRALKLW 122 + +SP+ + + ++K+W Sbjct: 240 LCFSPN-RYWLCAATESSIKIW 260 Score = 43.1 bits (100), Expect = 5e-04 Identities = 30/116 (25%), Positives = 51/116 (43%), Gaps = 18/116 (15%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SG D + LW+ K+ + G +++ + FSP+ WL +A+ + S+K+W+ + Sbjct: 210 SGGKDGVILLWDLAEGKRLYSLDAG--SIIHALCFSPNRYWLCAAT-ESSIKIWDLESKS 266 Query: 355 FV------------------TAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDI 242 V T + V ++WSAD L SG D ++VW I Sbjct: 267 IVEDLKVDLKTEADAAIGGDTTTKKKVIYCTSLNWSADGSTLFSGYTDGVVRVWGI 322
>GBLP_NICPL (P93340) Guanine nucleotide-binding protein beta subunit-like| protein Length = 326 Score = 85.9 bits (211), Expect = 7e-17 Identities = 48/146 (32%), Positives = 79/146 (54%), Gaps = 8/146 (5%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQ----PKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNG 368 + S D ++ +W T P+ R+TGH V V S DG + S S+D ++LW+ Sbjct: 34 TSSRDKSIIVWSLTKDGPQYGVPRRRLTGHGHFVQDVVLSSDGMFALSGSWDGELRLWDL 93 Query: 367 ITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDI--RARKLKQDLPGHADEV 194 G F GH DV +++SAD+R ++S S+D ++++W+ + + QD H+D V Sbjct: 94 QAGTTARRFVGHTKDVLSVAFSADNRQIVSASRDKSIRLWNTLGECKYIIQDGDSHSDWV 153 Query: 193 YAVDWSPDG--EKVVSGGKDRALKLW 122 V +SP+ +VSG DR +K+W Sbjct: 154 SCVRFSPNNLQPTIVSGSWDRTVKIW 179 Score = 77.8 bits (190), Expect = 2e-14 Identities = 52/142 (36%), Positives = 72/142 (50%), Gaps = 4/142 (2%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWN--GIT 362 SGS D + LW+ + R GH K V V FS D + + SAS DKS++LWN G Sbjct: 81 SGSWDGELRLWDLQAGTTAR-RFVGHTKDVLSVAFSADNRQIVSASRDKSIRLWNTLGEC 139 Query: 361 GKFVTAFRGHVADVYQISWSADSR--LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYA 188 + H V + +S ++ ++SGS D T+K+W++ KL+ L GH V Sbjct: 140 KYIIQDGDSHSDWVSCVRFSPNNLQPTIVSGSWDRTVKIWNLTNCKLRATLAGHTGYVNT 199 Query: 187 VDWSPDGEKVVSGGKDRALKLW 122 SPDG SGGKD + LW Sbjct: 200 TAVSPDGSLCASGGKDGVILLW 221 Score = 59.3 bits (142), Expect = 7e-09 Identities = 43/156 (27%), Positives = 73/156 (46%), Gaps = 18/156 (11%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SGS D T+ +W T K +A + GH VN SPDG AS D + LW+ GK Sbjct: 169 SGSWDRTVKIWNLTNCKL-RATLAGHTGYVNTTAVSPDGSLCASGGKDGVILLWDLAEGK 227 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLP------------ 212 + + + ++ + +S + R L + +S++K+WD+ ++ + DL Sbjct: 228 KLYSLESG-SIIHSLCFSPN-RYWLCAATESSIKIWDLESKTIVDDLKVDLKQESEMSAE 285 Query: 211 ----GHADEVY--AVDWSPDGEKVVSGGKDRALKLW 122 G +Y ++ WS DG + SG D +++W Sbjct: 286 GTASGKNKVIYCTSLGWSADGSTLFSGYTDGLIRVW 321 Score = 49.7 bits (117), Expect = 5e-06 Identities = 39/142 (27%), Positives = 65/142 (45%), Gaps = 4/142 (2%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTG--HQKVVNHVYFSPDG--QWLASASFDKSVKLWNG 368 S S D ++ LW T+ + G H V+ V FSP+ + S S+D++VK+WN Sbjct: 123 SASRDKSIRLWN-TLGECKYIIQDGDSHSDWVSCVRFSPNNLQPTIVSGSWDRTVKIWNL 181 Query: 367 ITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYA 188 K GH V + S D L SG KD + +WD+ K L +++ Sbjct: 182 TNCKLRATLAGHTGYVNTTAVSPDGSLCASGGKDGVILLWDLAEGKKLYSLES-GSIIHS 240 Query: 187 VDWSPDGEKVVSGGKDRALKLW 122 + +SP+ + + ++K+W Sbjct: 241 LCFSPN-RYWLCAATESSIKIW 261 Score = 43.5 bits (101), Expect = 4e-04 Identities = 28/116 (24%), Positives = 52/116 (44%), Gaps = 18/116 (15%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWN----- 371 SG D + LW+ K+ + +G +++ + FSP+ WL +A+ + S+K+W+ Sbjct: 211 SGGKDGVILLWDLAEGKKLYSLESG--SIIHSLCFSPNRYWLCAAT-ESSIKIWDLESKT 267 Query: 370 -------------GITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDI 242 ++ + + + V + WSAD L SG D ++VW I Sbjct: 268 IVDDLKVDLKQESEMSAEGTASGKNKVIYCTSLGWSADGSTLFSGYTDGLIRVWGI 323
>TAF5_YEAST (P38129) Transcription initiation factor TFIID subunit 5| (TBP-associated factor 5) (TBP-associated factor 90 kDa) (TAFII-90) Length = 798 Score = 85.5 bits (210), Expect = 9e-17 Identities = 47/139 (33%), Positives = 74/139 (53%), Gaps = 1/139 (0%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 + S D T LW P GH V+ V F P+G ++ + S DK+ ++W+ TG Sbjct: 584 TASHDQTARLWSCD-HIYPLRIFAGHLNDVDCVSFHPNGCYVFTGSSDKTCRMWDVSTGD 642 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHA-DEVYAVDW 179 V F GH A V I+ D R L +GS+D + VWDI K + + GH + +Y++ + Sbjct: 643 SVRLFLGHTAPVISIAVCPDGRWLSTGSEDGIINVWDIGTGKRLKQMRGHGKNAIYSLSY 702 Query: 178 SPDGEKVVSGGKDRALKLW 122 S +G ++SGG D +++W Sbjct: 703 SKEGNVLISGGADHTVRVW 721 Score = 70.9 bits (172), Expect = 2e-12 Identities = 35/116 (30%), Positives = 60/116 (51%) Frame = -2 Query: 469 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 290 + GH V FSPD ++L S S DK+V+LW+ T + +++GH V+ +S+S Sbjct: 521 LVGHSGTVYSTSFSPDNKYLLSGSEDKTVRLWSMDTHTALVSYKGHNHPVWDVSFSPLGH 580 Query: 289 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 + S D T ++W + GH ++V V + P+G V +G D+ ++W Sbjct: 581 YFATASHDQTARLWSCDHIYPLRIFAGHLNDVDCVSFHPNGCYVFTGSSDKTCRMW 636 Score = 67.8 bits (164), Expect = 2e-11 Identities = 35/101 (34%), Positives = 59/101 (58%), Gaps = 2/101 (1%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARM-TGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITG 359 +GS D T +W+ +S R+ GH V + PDG+WL++ S D + +W+ TG Sbjct: 626 TGSSDKTCRMWD--VSTGDSVRLFLGHTAPVISIAVCPDGRWLSTGSEDGIINVWDIGTG 683 Query: 358 KFVTAFRGHVAD-VYQISWSADSRLLLSGSKDSTLKVWDIR 239 K + RGH + +Y +S+S + +L+SG D T++VWD++ Sbjct: 684 KRLKQMRGHGKNAIYSLSYSKEGNVLISGGADHTVRVWDLK 724
>KTNB1_STRPU (O61585) Katanin p80 WD40-containing subunit B1 (Katanin p80| subunit B1) (p80 katanin) Length = 690 Score = 84.7 bits (208), Expect = 1e-16 Identities = 43/138 (31%), Positives = 78/138 (56%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 +GS TM +++ +K + +TGH+ + + F P G+++AS S D +VKLW+ Sbjct: 76 AGSQSGTMKIYDLEPAKIVRT-LTGHRNSIRCMDFHPFGEFVASGSTDTNVKLWDVRRKG 134 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 + ++GH V I +S D + L++ S+D+T+K+WD+ KL Q+ H V +++ Sbjct: 135 CIYTYKGHSDQVNMIKFSPDGKWLVTASEDTTIKLWDLTMGKLFQEFKNHTGGVTGIEFH 194 Query: 175 PDGEKVVSGGKDRALKLW 122 P+ + SG DR ++ W Sbjct: 195 PNEFLLASGSSDRTVQFW 212 Score = 83.2 bits (204), Expect = 4e-16 Identities = 46/132 (34%), Positives = 66/132 (50%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SGS D + LW+ K GH VN + FSPDG+WL +AS D ++KLW+ GK Sbjct: 118 SGSTDTNVKLWDVR-RKGCIYTYKGHSDQVNMIKFSPDGKWLVTASEDTTIKLWDLTMGK 176 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 F+ H V I + + LL SGS D T++ WD+ +L A V ++ + Sbjct: 177 LFQEFKNHTGGVTGIEFHPNEFLLASGSSDRTVQFWDLETFQLVSSTSPGASAVRSISFH 236 Query: 175 PDGEKVVSGGKD 140 PDG + +D Sbjct: 237 PDGSYLFCSSQD 248 Score = 70.5 bits (171), Expect = 3e-12 Identities = 34/117 (29%), Positives = 61/117 (52%), Gaps = 1/117 (0%) Frame = -2 Query: 469 MTGHQKVVNHVYFSP-DGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADS 293 + H VN + P G+ + + DK V LW + + GH + V + +++ Sbjct: 12 LVAHSSNVNCLALGPMSGRVMVTGGEDKKVNLWAVGKQNCIISLSGHTSPVDSVKFNSSE 71 Query: 292 RLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 L+++GS+ T+K++D+ K+ + L GH + + +D+ P GE V SG D +KLW Sbjct: 72 ELVVAGSQSGTMKIYDLEPAKIVRTLTGHRNSIRCMDFHPFGEFVASGSTDTNVKLW 128 Score = 70.1 bits (170), Expect = 4e-12 Identities = 38/139 (27%), Positives = 72/139 (51%), Gaps = 1/139 (0%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKA-RMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITG 359 +G +D + LW + KQ ++GH V+ V F+ + + + S ++K+++ Sbjct: 34 TGGEDKKVNLW--AVGKQNCIISLSGHTSPVDSVKFNSSEELVVAGSQSGTMKIYDLEPA 91 Query: 358 KFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDW 179 K V GH + + + + SGS D+ +K+WD+R + GH+D+V + + Sbjct: 92 KIVRTLTGHRNSIRCMDFHPFGEFVASGSTDTNVKLWDVRRKGCIYTYKGHSDQVNMIKF 151 Query: 178 SPDGEKVVSGGKDRALKLW 122 SPDG+ +V+ +D +KLW Sbjct: 152 SPDGKWLVTASEDTTIKLW 170
>LIS1_RAT (P63004) Platelet-activating factor acetylhydrolase IB alpha| subunit (PAF acetylhydrolase 45 kDa subunit) (PAF-AH 45 kDa subunit) (PAF-AH alpha) (PAFAH alpha) (Lissencephaly-1 protein) (LIS-1) Length = 409 Score = 84.7 bits (208), Expect = 1e-16 Identities = 41/119 (34%), Positives = 66/119 (55%) Frame = -2 Query: 478 KARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSA 299 K ++GH+ V V F P + SAS D ++K+W+ TG F +GH V IS+ Sbjct: 100 KYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDH 159 Query: 298 DSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 +LL S S D T+K+WD + + + + GH V +V P+G+ +VS +D+ +K+W Sbjct: 160 SGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMW 218 Score = 76.3 bits (186), Expect = 5e-14 Identities = 47/158 (29%), Positives = 75/158 (47%), Gaps = 20/158 (12%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 S S D T+ LW+ + + M GH V+ V P+G + SAS DK++K+W TG Sbjct: 166 SCSADMTIKLWDFQGFECIRT-MHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGY 224 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 V F GH V + + D L+ S S D T++VW + ++ K +L H V + W+ Sbjct: 225 CVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWA 284 Query: 175 PD--------------------GEKVVSGGKDRALKLW 122 P+ G ++SG +D+ +K+W Sbjct: 285 PESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMW 322 Score = 68.9 bits (167), Expect = 8e-12 Identities = 43/158 (27%), Positives = 78/158 (49%), Gaps = 20/158 (12%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPD--------------------GQ 416 S S+D T+ +W +K+ KA + H+ VV + ++P+ G Sbjct: 250 SCSNDQTVRVWV-VATKECKAELREHEHVVECISWAPESSYSSISEATGSETKKSGKPGP 308 Query: 415 WLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRA 236 +L S S DK++K+W+ TG + GH V + + + + +LS + D TL+VWD + Sbjct: 309 FLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKN 368 Query: 235 RKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 ++ + L H V ++D+ VV+G D+ +K+W Sbjct: 369 KRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVW 406 Score = 67.8 bits (164), Expect = 2e-11 Identities = 36/139 (25%), Positives = 70/139 (50%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 S S+D T+ +W+ + + GH V + F G+ LAS S D ++KLW+ + Sbjct: 124 SASEDATIKVWDYETGDFERT-LKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQGFE 182 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 + GH +V ++ + ++S S+D T+K+W+++ + GH + V V + Sbjct: 183 CIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPN 242 Query: 175 PDGEKVVSGGKDRALKLWM 119 DG + S D+ +++W+ Sbjct: 243 QDGTLIASCSNDQTVRVWV 261 Score = 48.5 bits (114), Expect = 1e-05 Identities = 26/99 (26%), Positives = 50/99 (50%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SGS D T+ +W+ + + GH V V F G+++ S + DK++++W+ + Sbjct: 312 SGSRDKTIKMWDVSTG-MCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKR 370 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIR 239 + H V + + + +++GS D T+KVW+ R Sbjct: 371 CMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWECR 409
>LIS1_PANTR (Q5IS43) Platelet-activating factor acetylhydrolase IB alpha| subunit (PAF acetylhydrolase 45 kDa subunit) (PAF-AH 45 kDa subunit) (PAF-AH alpha) (PAFAH alpha) (Lissencephaly-1 protein) (LIS-1) Length = 409 Score = 84.7 bits (208), Expect = 1e-16 Identities = 41/119 (34%), Positives = 66/119 (55%) Frame = -2 Query: 478 KARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSA 299 K ++GH+ V V F P + SAS D ++K+W+ TG F +GH V IS+ Sbjct: 100 KYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDH 159 Query: 298 DSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 +LL S S D T+K+WD + + + + GH V +V P+G+ +VS +D+ +K+W Sbjct: 160 SGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMW 218 Score = 76.3 bits (186), Expect = 5e-14 Identities = 47/158 (29%), Positives = 75/158 (47%), Gaps = 20/158 (12%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 S S D T+ LW+ + + M GH V+ V P+G + SAS DK++K+W TG Sbjct: 166 SCSADMTIKLWDFQGFECIRT-MHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGY 224 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 V F GH V + + D L+ S S D T++VW + ++ K +L H V + W+ Sbjct: 225 CVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWA 284 Query: 175 PD--------------------GEKVVSGGKDRALKLW 122 P+ G ++SG +D+ +K+W Sbjct: 285 PESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMW 322 Score = 67.8 bits (164), Expect = 2e-11 Identities = 43/158 (27%), Positives = 78/158 (49%), Gaps = 20/158 (12%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPD--------------------GQ 416 S S+D T+ +W +K+ KA + H+ VV + ++P+ G Sbjct: 250 SCSNDQTVRVWV-VATKECKAELREHEHVVECISWAPESSYSSISEATGSETKKSGKPGP 308 Query: 415 WLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRA 236 +L S S DK++K+W+ TG + GH V + + + + +LS + D TL+VWD + Sbjct: 309 FLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKN 368 Query: 235 RKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 ++ + L H V ++D+ VV+G D+ +K+W Sbjct: 369 KRCMKTLNAHEHFVTSLDFHKTAPYVVTGFVDQTVKVW 406 Score = 67.8 bits (164), Expect = 2e-11 Identities = 36/139 (25%), Positives = 70/139 (50%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 S S+D T+ +W+ + + GH V + F G+ LAS S D ++KLW+ + Sbjct: 124 SASEDATIKVWDYETGDFERT-LKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQGFE 182 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 + GH +V ++ + ++S S+D T+K+W+++ + GH + V V + Sbjct: 183 CIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPN 242 Query: 175 PDGEKVVSGGKDRALKLWM 119 DG + S D+ +++W+ Sbjct: 243 QDGTLIASCSNDQTVRVWV 261 Score = 46.2 bits (108), Expect = 6e-05 Identities = 25/99 (25%), Positives = 49/99 (49%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SGS D T+ +W+ + + GH V V F G+++ S + DK++++W+ + Sbjct: 312 SGSRDKTIKMWDVSTG-MCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKR 370 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIR 239 + H V + + + +++G D T+KVW+ R Sbjct: 371 CMKTLNAHEHFVTSLDFHKTAPYVVTGFVDQTVKVWECR 409
>LIS1_MOUSE (P63005) Platelet-activating factor acetylhydrolase IB alpha| subunit (PAF acetylhydrolase 45 kDa subunit) (PAF-AH 45 kDa subunit) (PAF-AH alpha) (PAFAH alpha) (Lissencephaly-1 protein) (LIS-1) Length = 409 Score = 84.7 bits (208), Expect = 1e-16 Identities = 41/119 (34%), Positives = 66/119 (55%) Frame = -2 Query: 478 KARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSA 299 K ++GH+ V V F P + SAS D ++K+W+ TG F +GH V IS+ Sbjct: 100 KYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDH 159 Query: 298 DSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 +LL S S D T+K+WD + + + + GH V +V P+G+ +VS +D+ +K+W Sbjct: 160 SGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMW 218 Score = 76.3 bits (186), Expect = 5e-14 Identities = 47/158 (29%), Positives = 75/158 (47%), Gaps = 20/158 (12%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 S S D T+ LW+ + + M GH V+ V P+G + SAS DK++K+W TG Sbjct: 166 SCSADMTIKLWDFQGFECIRT-MHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGY 224 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 V F GH V + + D L+ S S D T++VW + ++ K +L H V + W+ Sbjct: 225 CVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWA 284 Query: 175 PD--------------------GEKVVSGGKDRALKLW 122 P+ G ++SG +D+ +K+W Sbjct: 285 PESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMW 322 Score = 68.9 bits (167), Expect = 8e-12 Identities = 43/158 (27%), Positives = 78/158 (49%), Gaps = 20/158 (12%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPD--------------------GQ 416 S S+D T+ +W +K+ KA + H+ VV + ++P+ G Sbjct: 250 SCSNDQTVRVWV-VATKECKAELREHEHVVECISWAPESSYSSISEATGSETKKSGKPGP 308 Query: 415 WLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRA 236 +L S S DK++K+W+ TG + GH V + + + + +LS + D TL+VWD + Sbjct: 309 FLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKN 368 Query: 235 RKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 ++ + L H V ++D+ VV+G D+ +K+W Sbjct: 369 KRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVW 406 Score = 67.8 bits (164), Expect = 2e-11 Identities = 36/139 (25%), Positives = 70/139 (50%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 S S+D T+ +W+ + + GH V + F G+ LAS S D ++KLW+ + Sbjct: 124 SASEDATIKVWDYETGDFERT-LKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQGFE 182 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 + GH +V ++ + ++S S+D T+K+W+++ + GH + V V + Sbjct: 183 CIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPN 242 Query: 175 PDGEKVVSGGKDRALKLWM 119 DG + S D+ +++W+ Sbjct: 243 QDGTLIASCSNDQTVRVWV 261 Score = 48.5 bits (114), Expect = 1e-05 Identities = 26/99 (26%), Positives = 50/99 (50%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SGS D T+ +W+ + + GH V V F G+++ S + DK++++W+ + Sbjct: 312 SGSRDKTIKMWDVSTG-MCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKR 370 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIR 239 + H V + + + +++GS D T+KVW+ R Sbjct: 371 CMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWECR 409
>LIS1_HUMAN (P43034) Platelet-activating factor acetylhydrolase IB alpha| subunit (PAF acetylhydrolase 45 kDa subunit) (PAF-AH 45 kDa subunit) (PAF-AH alpha) (PAFAH alpha) (Lissencephaly-1 protein) (LIS-1) Length = 409 Score = 84.7 bits (208), Expect = 1e-16 Identities = 41/119 (34%), Positives = 66/119 (55%) Frame = -2 Query: 478 KARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSA 299 K ++GH+ V V F P + SAS D ++K+W+ TG F +GH V IS+ Sbjct: 100 KYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDH 159 Query: 298 DSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 +LL S S D T+K+WD + + + + GH V +V P+G+ +VS +D+ +K+W Sbjct: 160 SGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMW 218 Score = 76.3 bits (186), Expect = 5e-14 Identities = 47/158 (29%), Positives = 75/158 (47%), Gaps = 20/158 (12%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 S S D T+ LW+ + + M GH V+ V P+G + SAS DK++K+W TG Sbjct: 166 SCSADMTIKLWDFQGFECIRT-MHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGY 224 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 V F GH V + + D L+ S S D T++VW + ++ K +L H V + W+ Sbjct: 225 CVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWA 284 Query: 175 PD--------------------GEKVVSGGKDRALKLW 122 P+ G ++SG +D+ +K+W Sbjct: 285 PESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMW 322 Score = 68.9 bits (167), Expect = 8e-12 Identities = 43/158 (27%), Positives = 78/158 (49%), Gaps = 20/158 (12%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPD--------------------GQ 416 S S+D T+ +W +K+ KA + H+ VV + ++P+ G Sbjct: 250 SCSNDQTVRVWV-VATKECKAELREHEHVVECISWAPESSYSSISEATGSETKKSGKPGP 308 Query: 415 WLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRA 236 +L S S DK++K+W+ TG + GH V + + + + +LS + D TL+VWD + Sbjct: 309 FLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKN 368 Query: 235 RKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 ++ + L H V ++D+ VV+G D+ +K+W Sbjct: 369 KRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVW 406 Score = 67.8 bits (164), Expect = 2e-11 Identities = 36/139 (25%), Positives = 70/139 (50%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 S S+D T+ +W+ + + GH V + F G+ LAS S D ++KLW+ + Sbjct: 124 SASEDATIKVWDYETGDFERT-LKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQGFE 182 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 + GH +V ++ + ++S S+D T+K+W+++ + GH + V V + Sbjct: 183 CIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPN 242 Query: 175 PDGEKVVSGGKDRALKLWM 119 DG + S D+ +++W+ Sbjct: 243 QDGTLIASCSNDQTVRVWV 261 Score = 48.5 bits (114), Expect = 1e-05 Identities = 26/99 (26%), Positives = 50/99 (50%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SGS D T+ +W+ + + GH V V F G+++ S + DK++++W+ + Sbjct: 312 SGSRDKTIKMWDVSTG-MCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKR 370 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIR 239 + H V + + + +++GS D T+KVW+ R Sbjct: 371 CMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWECR 409
>GBLP_CAEEL (Q21215) Guanine nucleotide-binding protein beta subunit 2-like 1| Length = 324 Score = 84.3 bits (207), Expect = 2e-16 Identities = 51/149 (34%), Positives = 81/149 (54%), Gaps = 11/149 (7%) Frame = -2 Query: 535 SGSDDFTMFLWE----PTISKQPKAR----MTGHQKVVNHVYFSPDGQWLASASFDKSVK 380 S S D T+ +W+ + + P R +TGH V+ V S DGQ+ S S+DK+++ Sbjct: 34 SSSRDKTILVWDVDSVAPVDEGPIGRPVRSLTGHNHFVSDVVISSDGQFALSGSWDKTLR 93 Query: 379 LWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRAR-KLKQDLPGHA 203 LW+ G F H DV +++SAD+R ++SGS+D ++K+W+ A+ K H Sbjct: 94 LWDLNQGVSTRQFISHTKDVLSVAFSADNRQIVSGSRDKSIKLWNTLAQCKYTITDDCHT 153 Query: 202 DEVYAVDWSPDGEK--VVSGGKDRALKLW 122 D V V +SP +VS G D+ +K+W Sbjct: 154 DWVSTVRFSPSNRDPVIVSAGWDKVVKVW 182 Score = 58.9 bits (141), Expect = 9e-09 Identities = 41/124 (33%), Positives = 59/124 (47%), Gaps = 2/124 (1%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQ--WLASASFDKSVKLWNGIT 362 SGS D ++ LW + H V+ V FSP + + SA +DK VK+WN Sbjct: 127 SGSRDKSIKLWNTLAQCKYTITDDCHTDWVSTVRFSPSNRDPVIVSAGWDKVVKVWNLGN 186 Query: 361 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 182 + T GH V ++ S D L SG KD +WD+ K LPG+ D + A+ Sbjct: 187 CRLKTNHIGHTGYVNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLPGN-DVINAMS 245 Query: 181 WSPD 170 +SP+ Sbjct: 246 FSPN 249 Score = 54.7 bits (130), Expect = 2e-07 Identities = 35/129 (27%), Positives = 59/129 (45%), Gaps = 10/129 (7%) Frame = -2 Query: 478 KARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSA 299 K GH VN V SPDG AS D LW+ GK + G+ DV + Sbjct: 190 KTNHIGHTGYVNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLPGN--DVINAMSFS 247 Query: 298 DSRLLLSGSKDSTLKVWDIRARKLKQDLP----------GHADEVYAVDWSPDGEKVVSG 149 +R L + S++K+WD+ +K ++L G + + ++ WS DG+ + +G Sbjct: 248 PNRYWLCAAVGSSIKIWDLEDKKEIEELKPEIASSGSSRGSSPQCISLAWSQDGQTLFAG 307 Query: 148 GKDRALKLW 122 D ++++ Sbjct: 308 YTDNIIRVY 316 Score = 42.0 bits (97), Expect = 0.001 Identities = 29/90 (32%), Positives = 41/90 (45%), Gaps = 11/90 (12%) Frame = -2 Query: 358 KFVTAFRGHVADVYQISWSA--DSRLLLSGSKDSTLKVWDIRA---------RKLKQDLP 212 K GH V QI+ D +LS S+D T+ VWD+ + + + L Sbjct: 6 KLTGTLEGHTGWVTQIATYTRNDKTTVLSSSRDKTILVWDVDSVAPVDEGPIGRPVRSLT 65 Query: 211 GHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 GH V V S DG+ +SG D+ L+LW Sbjct: 66 GHNHFVSDVVISSDGQFALSGSWDKTLRLW 95
>WS17_SCHMA (Q26544) WD-repeat protein SL1-17| Length = 301 Score = 84.3 bits (207), Expect = 2e-16 Identities = 40/117 (34%), Positives = 72/117 (61%), Gaps = 1/117 (0%) Frame = -2 Query: 469 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVT-AFRGHVADVYQISWSADS 293 + GH V V FSPDG+ LASAS DK +K+++ G+ V + GH V + +++D+ Sbjct: 182 LDGHATPVRSVSFSPDGRLLASASDDKQIKVFDVRDGRLVIPSLNGHKGWVVSVDFASDN 241 Query: 292 RLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 R L++ S D ++++WD+ +++ K H D+V+ +SP G ++S G DR++ ++ Sbjct: 242 RHLVTASTDCSVRIWDLASKEEKHCFNTHEDQVWCARYSPQGNNIISVGDDRSIMIY 298 Score = 58.9 bits (141), Expect = 9e-09 Identities = 37/130 (28%), Positives = 65/130 (50%), Gaps = 1/130 (0%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISK-QPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITG 359 +GS D + WE T S+ + + GH+ V V + G AS+S D + LW+ TG Sbjct: 34 TGSLDNGLIAWEWTNSQLKCLYQFEGHRLGVISVDINSTGTLAASSSLDSQILLWDLETG 93 Query: 358 KFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDW 179 + + G AD + I++S DSR L +GS + + +++ + + + VY + + Sbjct: 94 RLTKTYDGDPADTWTIAFSPDSRFLATGSHTGCVNMINVQTAQKEGSIQLEGKFVYXLAY 153 Query: 178 SPDGEKVVSG 149 DG K+ +G Sbjct: 154 ISDGSKLAAG 163 Score = 36.2 bits (82), Expect = 0.059 Identities = 23/96 (23%), Positives = 46/96 (47%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 S SDD + +++ + + GH+ V V F+ D + L +AS D SV++W+ + + Sbjct: 203 SASDDKQIKVFDVRDGRLVIPSLNGHKGWVVSVDFASDNRHLVTASTDCSVRIWDLASKE 262 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVW 248 F H V+ +S ++S D ++ ++ Sbjct: 263 EKHCFNTHEDQVWCARYSPQGNNIISVGDDRSIMIY 298 Score = 29.6 bits (65), Expect = 5.6 Identities = 19/79 (24%), Positives = 35/79 (44%), Gaps = 6/79 (7%) Frame = -2 Query: 340 RGHVADVYQISW----SADSRLLLSGSKDSTLKVWDIRARKLK--QDLPGHADEVYAVDW 179 + H ++ +W + + + +++GS D+ L W+ +LK GH V +VD Sbjct: 10 QAHKEGIWCCTWGENRNRNKQYIITGSLDNGLIAWEWTNSQLKCLYQFEGHRLGVISVDI 69 Query: 178 SPDGEKVVSGGKDRALKLW 122 + G S D + LW Sbjct: 70 NSTGTLAASSSLDSQILLW 88
>LIS1_BOVIN (P43033) Platelet-activating factor acetylhydrolase IB alpha| subunit (PAF acetylhydrolase 45 kDa subunit) (PAF-AH 45 kDa subunit) (PAF-AH alpha) (PAFAH alpha) (Lissencephaly-1 protein) (LIS-1) Length = 409 Score = 84.3 bits (207), Expect = 2e-16 Identities = 41/119 (34%), Positives = 66/119 (55%) Frame = -2 Query: 478 KARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSA 299 K ++GH+ V V F P + SAS D ++K+W+ TG F +GH V IS+ Sbjct: 100 KYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVEDISFDH 159 Query: 298 DSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 +LL S S D T+K+WD + + + + GH V +V P+G+ +VS +D+ +K+W Sbjct: 160 SGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMW 218 Score = 76.3 bits (186), Expect = 5e-14 Identities = 47/158 (29%), Positives = 75/158 (47%), Gaps = 20/158 (12%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 S S D T+ LW+ + + M GH V+ V P+G + SAS DK++K+W TG Sbjct: 166 SCSADMTIKLWDFQGFECIRT-MHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGY 224 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 V F GH V + + D L+ S S D T++VW + ++ K +L H V + W+ Sbjct: 225 CVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWA 284 Query: 175 PD--------------------GEKVVSGGKDRALKLW 122 P+ G ++SG +D+ +K+W Sbjct: 285 PESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMW 322 Score = 68.9 bits (167), Expect = 8e-12 Identities = 43/158 (27%), Positives = 78/158 (49%), Gaps = 20/158 (12%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPD--------------------GQ 416 S S+D T+ +W +K+ KA + H+ VV + ++P+ G Sbjct: 250 SCSNDQTVRVWV-VATKECKAELREHEHVVECISWAPESSYSSISEATGSETKKSGKPGP 308 Query: 415 WLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRA 236 +L S S DK++K+W+ TG + GH V + + + + +LS + D TL+VWD + Sbjct: 309 FLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKN 368 Query: 235 RKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 ++ + L H V ++D+ VV+G D+ +K+W Sbjct: 369 KRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVW 406 Score = 67.8 bits (164), Expect = 2e-11 Identities = 36/139 (25%), Positives = 70/139 (50%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 S S+D T+ +W+ + + GH V + F G+ LAS S D ++KLW+ + Sbjct: 124 SASEDATIKVWDYETGDFERT-LKGHTDSVEDISFDHSGKLLASCSADMTIKLWDFQGFE 182 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 + GH +V ++ + ++S S+D T+K+W+++ + GH + V V + Sbjct: 183 CIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPN 242 Query: 175 PDGEKVVSGGKDRALKLWM 119 DG + S D+ +++W+ Sbjct: 243 QDGTLIASCSNDQTVRVWV 261 Score = 48.5 bits (114), Expect = 1e-05 Identities = 26/99 (26%), Positives = 50/99 (50%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SGS D T+ +W+ + + GH V V F G+++ S + DK++++W+ + Sbjct: 312 SGSRDKTIKMWDVSTG-MCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKR 370 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIR 239 + H V + + + +++GS D T+KVW+ R Sbjct: 371 CMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWECR 409
>LIS1_MACFA (Q8HXX0) Platelet-activating factor acetylhydrolase IB alpha| subunit (PAF acetylhydrolase 45 kDa subunit) (PAF-AH 45 kDa subunit) (PAF-AH alpha) (PAFAH alpha) (Lissencephaly-1 protein) (LIS-1) Length = 409 Score = 84.0 bits (206), Expect = 2e-16 Identities = 41/119 (34%), Positives = 66/119 (55%) Frame = -2 Query: 478 KARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSA 299 K ++GH+ V V F P + SAS D ++K+W+ TG F +GH V IS+ Sbjct: 100 KYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDH 159 Query: 298 DSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 +LL S S D T+K+WD + + + + GH V +V P+G+ +VS +D+ +K+W Sbjct: 160 SGKLLTSCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHLVSASRDKTIKMW 218 Score = 77.0 bits (188), Expect = 3e-14 Identities = 48/158 (30%), Positives = 75/158 (47%), Gaps = 20/158 (12%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 S S D T+ LW+ + + M GH V+ V P+G L SAS DK++K+W TG Sbjct: 166 SCSADMTIKLWDFQGFECIRT-MHGHDHNVSSVAIMPNGDHLVSASRDKTIKMWEVQTGY 224 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 V F GH V + + D L+ S S D T++VW + ++ K +L H V + W+ Sbjct: 225 CVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWA 284 Query: 175 PD--------------------GEKVVSGGKDRALKLW 122 P+ G ++SG +D+ +K+W Sbjct: 285 PESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMW 322 Score = 68.9 bits (167), Expect = 8e-12 Identities = 43/158 (27%), Positives = 78/158 (49%), Gaps = 20/158 (12%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPD--------------------GQ 416 S S+D T+ +W +K+ KA + H+ VV + ++P+ G Sbjct: 250 SCSNDQTVRVWV-VATKECKAELREHEHVVECISWAPESSYSSISEATGSETKKSGKPGP 308 Query: 415 WLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRA 236 +L S S DK++K+W+ TG + GH V + + + + +LS + D TL+VWD + Sbjct: 309 FLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKN 368 Query: 235 RKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 ++ + L H V ++D+ VV+G D+ +K+W Sbjct: 369 KRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVW 406 Score = 67.0 bits (162), Expect = 3e-11 Identities = 36/139 (25%), Positives = 69/139 (49%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 S S+D T+ +W+ + + GH V + F G+ L S S D ++KLW+ + Sbjct: 124 SASEDATIKVWDYETGDFERT-LKGHTDSVQDISFDHSGKLLTSCSADMTIKLWDFQGFE 182 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 + GH +V ++ + L+S S+D T+K+W+++ + GH + V V + Sbjct: 183 CIRTMHGHDHNVSSVAIMPNGDHLVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPN 242 Query: 175 PDGEKVVSGGKDRALKLWM 119 DG + S D+ +++W+ Sbjct: 243 QDGTLIASCSNDQTVRVWV 261 Score = 48.5 bits (114), Expect = 1e-05 Identities = 26/99 (26%), Positives = 50/99 (50%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SGS D T+ +W+ + + GH V V F G+++ S + DK++++W+ + Sbjct: 312 SGSRDKTIKMWDVSTG-MCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKR 370 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIR 239 + H V + + + +++GS D T+KVW+ R Sbjct: 371 CMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWECR 409
>GBLP_YEAST (P38011) Guanine nucleotide-binding protein beta subunit-like| protein (Receptor of activated protein kinase C 1) (RACK1) (Receptor for activated C kinase) Length = 318 Score = 84.0 bits (206), Expect = 2e-16 Identities = 50/148 (33%), Positives = 75/148 (50%), Gaps = 10/148 (6%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQ----PKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNG 368 S S D T+ W+ T Q P GH +V + DG + SAS+DK+++LW+ Sbjct: 34 SASRDKTLISWKLTGDDQKFGVPVRSFKGHSHIVQDCTLTADGAYALSASWDKTLRLWDV 93 Query: 367 ITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYA 188 TG+ F GH +DV + + +++SGS+D T+KVW I+ + L L GH D V Sbjct: 94 ATGETYQRFVGHKSDVMSVDIDKKASMIISGSRDKTIKVWTIKGQCL-ATLLGHNDWVSQ 152 Query: 187 VDWSP------DGEKVVSGGKDRALKLW 122 V P D ++S G D+ +K W Sbjct: 153 VRVVPNEKADDDSVTIISAGNDKMVKAW 180 Score = 51.6 bits (122), Expect = 1e-06 Identities = 37/129 (28%), Positives = 63/129 (48%), Gaps = 8/129 (6%) Frame = -2 Query: 484 QPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISW 305 Q +A GH +N + SPDG +ASA D + LWN K + +V+ +++ Sbjct: 186 QIEADFIGHNSNINTLTASPDGTLIASAGKDGEIMLWNLAAKKAMYTLSAQ-DEVFSLAF 244 Query: 304 SADSRLLLSGSKDSTLKVWDIRARKLKQDLP------GHADEVYAVD--WSPDGEKVVSG 149 S +R L+ + + +KV+ + + L DL A E +AV WS DG+ + +G Sbjct: 245 S-PNRYWLAAATATGIKVFSLDPQYLVDDLRPEFAGYSKAAEPHAVSLAWSADGQTLFAG 303 Query: 148 GKDRALKLW 122 D +++W Sbjct: 304 YTDNVIRVW 312 Score = 37.0 bits (84), Expect = 0.035 Identities = 26/78 (33%), Positives = 36/78 (46%), Gaps = 6/78 (7%) Frame = -2 Query: 337 GHVADVYQISWSADS-RLLLSGSKDSTLKVWDIRARKLKQDLP-----GHADEVYAVDWS 176 GH V ++ SA LLLS S+D TL W + K +P GH+ V + Sbjct: 14 GHNGWVTSLATSAGQPNLLLSASRDKTLISWKLTGDDQKFGVPVRSFKGHSHIVQDCTLT 73 Query: 175 PDGEKVVSGGKDRALKLW 122 DG +S D+ L+LW Sbjct: 74 ADGAYALSASWDKTLRLW 91 Score = 35.8 bits (81), Expect = 0.078 Identities = 26/106 (24%), Positives = 48/106 (45%), Gaps = 8/106 (7%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASA--------SFDKSVK 380 S D + LW +K+ ++ +V + + FSP+ WLA+A S D Sbjct: 212 SAGKDGEIMLWN-LAAKKAMYTLSAQDEVFS-LAFSPNRYWLAAATATGIKVFSLDPQY- 268 Query: 379 LWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDI 242 L + + +F + ++WSAD + L +G D+ ++VW + Sbjct: 269 LVDDLRPEFAGYSKAAEPHAVSLAWSADGQTLFAGYTDNVIRVWQV 314
>YZLL_CAEEL (Q93847) Hypothetical WD-repeat protein K04G11.4| Length = 395 Score = 84.0 bits (206), Expect = 2e-16 Identities = 37/113 (32%), Positives = 68/113 (60%) Frame = -2 Query: 460 HQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLL 281 H+K ++ + FSPDG+++ S S D S+K+W + + GH + + SWS+DS+L++ Sbjct: 106 HKKSISGIKFSPDGRYMGSGSADCSIKIWR-MDFVYEKTLMGHRLGINEFSWSSDSKLIV 164 Query: 280 SGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 S S D +KV+D+ + + + L GH + V+ ++P G + SG D +++W Sbjct: 165 SCSDDKLVKVFDVSSGRCVKTLKGHTNYVFCCCFNPSGTLIASGSFDETIRIW 217 Score = 75.1 bits (183), Expect = 1e-13 Identities = 41/138 (29%), Positives = 72/138 (52%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SGS D ++ +W + + GH+ +N +S D + + S S DK VK+++ +G+ Sbjct: 124 SGSADCSIKIWRMDFVYEKT--LMGHRLGINEFSWSSDSKLIVSCSDDKLVKVFDVSSGR 181 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 V +GH V+ ++ L+ SGS D T+++W R +PGH D V +V ++ Sbjct: 182 CVKTLKGHTNYVFCCCFNPSGTLIASGSFDETIRIWCARNGNTIFSIPGHEDPVSSVCFN 241 Query: 175 PDGEKVVSGGKDRALKLW 122 DG + SG D +++W Sbjct: 242 RDGAYLASGSYDGIVRIW 259 Score = 68.6 bits (166), Expect = 1e-11 Identities = 36/144 (25%), Positives = 75/144 (52%), Gaps = 6/144 (4%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SGS D + +W+ T K + + HV FSP+G+++ +++ + ++KLW+ + Sbjct: 249 SGSYDGIVRIWDSTTGTCVKTLIDEEHPPITHVKFSPNGKYILASNLNNTLKLWDYQKLR 308 Query: 355 FVTAFRGHVADVYQISWS---ADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAV 185 + + GH Y ++ + + ++SGS+D + +W+++ R++ Q L GH V Sbjct: 309 VLKEYTGHENSKYCVAANFSVTGGKWIVSGSEDHKVYIWNLQTREILQTLDGHNTAVMCT 368 Query: 184 DWSPDGEKVVSGG---KDRALKLW 122 D P G+ +++ D +K+W Sbjct: 369 DCHP-GQNIIASAALEPDMRIKIW 391 Score = 65.5 bits (158), Expect = 9e-11 Identities = 38/139 (27%), Positives = 70/139 (50%), Gaps = 1/139 (0%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 S SDD + +++ + + K + GH V F+P G +AS SFD+++++W G Sbjct: 165 SCSDDKLVKVFDVSSGRCVKT-LKGHTNYVFCCCFNPSGTLIASGSFDETIRIWCARNGN 223 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD-IRARKLKQDLPGHADEVYAVDW 179 + + GH V + ++ D L SGS D +++WD +K + + V + Sbjct: 224 TIFSIPGHEDPVSSVCFNRDGAYLASGSYDGIVRIWDSTTGTCVKTLIDEEHPPITHVKF 283 Query: 178 SPDGEKVVSGGKDRALKLW 122 SP+G+ +++ + LKLW Sbjct: 284 SPNGKYILASNLNNTLKLW 302
>GBLP_ARATH (O24456) Guanine nucleotide-binding protein beta subunit-like| protein (WD-40 repeat auxin-dependent protein ARCA) Length = 327 Score = 83.6 bits (205), Expect = 3e-16 Identities = 50/149 (33%), Positives = 79/149 (53%), Gaps = 11/149 (7%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKA------RMTGHQKVVNHVYFSPDGQWLASASFDKSVKLW 374 S S D ++ LW+ ++K KA R+TGH V V S DGQ+ S S+D ++LW Sbjct: 33 SASRDKSIILWK--LTKDDKAYGVAQRRLTGHSHFVEDVVLSSDGQFALSGSWDGELRLW 90 Query: 373 NGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRAR---KLKQDLPGHA 203 + G F GH DV +++S D+R ++S S+D T+K+W+ + + GH Sbjct: 91 DLAAGVSTRRFVGHTKDVLSVAFSLDNRQIVSASRDRTIKLWNTLGECKYTISEGGEGHR 150 Query: 202 DEVYAVDWSPD--GEKVVSGGKDRALKLW 122 D V V +SP+ +VS D+ +K+W Sbjct: 151 DWVSCVRFSPNTLQPTIVSASWDKTVKVW 179 Score = 65.1 bits (157), Expect = 1e-10 Identities = 42/128 (32%), Positives = 63/128 (49%), Gaps = 9/128 (7%) Frame = -2 Query: 478 KARMTGHQKVVNHVYFSPDG-QWLASASFDKSVKLWN--------GITGKFVTAFRGHVA 326 K M H +V + D + SAS DKS+ LW G+ + +T GH Sbjct: 8 KGTMRAHTDMVTAIATPIDNADIIVSASRDKSIILWKLTKDDKAYGVAQRRLT---GHSH 64 Query: 325 DVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGG 146 V + S+D + LSGS D L++WD+ A + GH +V +V +S D ++VS Sbjct: 65 FVEDVVLSSDGQFALSGSWDGELRLWDLAAGVSTRRFVGHTKDVLSVAFSLDNRQIVSAS 124 Query: 145 KDRALKLW 122 +DR +KLW Sbjct: 125 RDRTIKLW 132 Score = 58.9 bits (141), Expect = 9e-09 Identities = 45/146 (30%), Positives = 72/146 (49%), Gaps = 8/146 (5%) Frame = -2 Query: 535 SGSDDFTMFLWEP------TISKQPKARMTGHQKVVNHVYFSPDG--QWLASASFDKSVK 380 S S D T+ LW TIS+ + GH+ V+ V FSP+ + SAS+DK+VK Sbjct: 122 SASRDRTIKLWNTLGECKYTISEGGE----GHRDWVSCVRFSPNTLQPTIVSASWDKTVK 177 Query: 379 LWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHAD 200 +WN K + GH V ++ S D L SG KD + +WD+ K L ++ Sbjct: 178 VWNLSNCKLRSTLAGHTGYVSTVAVSPDGSLCASGGKDGVVLLWDLAEGKKLYSLEANS- 236 Query: 199 EVYAVDWSPDGEKVVSGGKDRALKLW 122 ++A+ +SP+ + + +K+W Sbjct: 237 VIHALCFSPN-RYWLCAATEHGIKIW 261 Score = 53.9 bits (128), Expect = 3e-07 Identities = 42/157 (26%), Positives = 75/157 (47%), Gaps = 19/157 (12%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 S S D T+ +W + K ++ + GH V+ V SPDG AS D V LW+ GK Sbjct: 169 SASWDKTVKVWNLSNCKL-RSTLAGHTGYVSTVAVSPDGSLCASGGKDGVVLLWDLAEGK 227 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARK----LKQDLPGHADE--- 197 + + + ++ + +S + R L + + +K+WD+ ++ LK DL A++ Sbjct: 228 KLYSLEANSV-IHALCFSPN-RYWLCAATEHGIKIWDLESKSIVEDLKVDLKAEAEKADN 285 Query: 196 ----------VY--AVDWSPDGEKVVSGGKDRALKLW 122 +Y +++WS DG + SG D +++W Sbjct: 286 SGPAATKRKVIYCTSLNWSADGSTLFSGYTDGVIRVW 322 Score = 41.2 bits (95), Expect = 0.002 Identities = 29/117 (24%), Positives = 50/117 (42%), Gaps = 19/117 (16%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SG D + LW+ +++ K V++ + FSP+ WL +A+ + +K+W+ + Sbjct: 211 SGGKDGVVLLWD--LAEGKKLYSLEANSVIHALCFSPNRYWLCAAT-EHGIKIWDLESKS 267 Query: 355 FV-------------------TAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDI 242 V A + V ++WSAD L SG D ++VW I Sbjct: 268 IVEDLKVDLKAEAEKADNSGPAATKRKVIYCTSLNWSADGSTLFSGYTDGVIRVWGI 324
>GBLP_CHLRE (P25387) Guanine nucleotide-binding protein beta subunit-like| protein Length = 318 Score = 83.6 bits (205), Expect = 3e-16 Identities = 48/146 (32%), Positives = 79/146 (54%), Gaps = 8/146 (5%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQ----PKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNG 368 S S D ++ +WE S+ + + GH V V S DGQ+ + S+D +++LW+ Sbjct: 34 SASRDKSVLVWELERSESNYGYARKALRGHSHFVQDVVISSDGQFCLTGSWDGTLRLWDL 93 Query: 367 ITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDI--RARKLKQDLPGHADEV 194 TG F GH DV +++S D+R ++SGS+D T+K+W+ + + GH + V Sbjct: 94 NTGTTTRRFVGHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLGECKYTIGEPEGHTEWV 153 Query: 193 YAVDWSP--DGEKVVSGGKDRALKLW 122 V +SP +VSGG D+ +K+W Sbjct: 154 SCVRFSPMTTNPIIVSGGWDKMVKVW 179 Score = 73.2 bits (178), Expect = 4e-13 Identities = 43/126 (34%), Positives = 63/126 (50%), Gaps = 7/126 (5%) Frame = -2 Query: 478 KARMTGHQKVVNHVY--FSPDGQWLASASFDKSVKLW-----NGITGKFVTAFRGHVADV 320 +A + GH V + P L SAS DKSV +W G A RGH V Sbjct: 8 RATLKGHTNWVTAIATPLDPSSNTLLSASRDKSVLVWELERSESNYGYARKALRGHSHFV 67 Query: 319 YQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKD 140 + S+D + L+GS D TL++WD+ + GH +V +V +S D ++VSG +D Sbjct: 68 QDVVISSDGQFCLTGSWDGTLRLWDLNTGTTTRRFVGHTKDVLSVAFSVDNRQIVSGSRD 127 Query: 139 RALKLW 122 + +KLW Sbjct: 128 KTIKLW 133 Score = 59.7 bits (143), Expect = 5e-09 Identities = 44/147 (29%), Positives = 64/147 (43%), Gaps = 9/147 (6%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SG D + +W T K K + GH VN V SPDG AS D LW+ GK Sbjct: 169 SGGWDKMVKVWNLTNCKL-KNNLVGHHGYVNTVTVSPDGSLCASGGKDGIAMLWDLAEGK 227 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGH-------ADE 197 + + DV + +R L + S++K+WD+ ++ + DL A Sbjct: 228 RLYSL--DAGDVIHCLCFSPNRYWLCAATQSSIKIWDLESKSIVDDLRPEFNITSKKAQV 285 Query: 196 VYAVD--WSPDGEKVVSGGKDRALKLW 122 Y V WS DG + SG D +++W Sbjct: 286 PYCVSLAWSADGSTLYSGYTDGQIRVW 312 Score = 53.5 bits (127), Expect = 4e-07 Identities = 42/141 (29%), Positives = 61/141 (43%), Gaps = 3/141 (2%) Frame = -2 Query: 535 SGSDDFTMFLWEPTIS-KQPKARMTGHQKVVNHVYFSP--DGQWLASASFDKSVKLWNGI 365 SGS D T+ LW K GH + V+ V FSP + S +DK VK+WN Sbjct: 123 SGSRDKTIKLWNTLGECKYTIGEPEGHTEWVSCVRFSPMTTNPIIVSGGWDKMVKVWNLT 182 Query: 364 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAV 185 K GH V ++ S D L SG KD +WD+ K L D ++ + Sbjct: 183 NCKLKNNLVGHHGYVNTVTVSPDGSLCASGGKDGIAMLWDLAEGKRLYSLDA-GDVIHCL 241 Query: 184 DWSPDGEKVVSGGKDRALKLW 122 +SP+ + ++K+W Sbjct: 242 CFSPN-RYWLCAATQSSIKIW 261 Score = 45.1 bits (105), Expect = 1e-04 Identities = 30/107 (28%), Positives = 52/107 (48%), Gaps = 9/107 (8%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWN----- 371 SG D LW+ K+ + G V++ + FSP+ WL +A+ S+K+W+ Sbjct: 211 SGGKDGIAMLWDLAEGKRLYSLDAGD--VIHCLCFSPNRYWLCAAT-QSSIKIWDLESKS 267 Query: 370 ---GITGKF-VTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDI 242 + +F +T+ + V ++WSAD L SG D ++VW + Sbjct: 268 IVDDLRPEFNITSKKAQVPYCVSLAWSADGSTLYSGYTDGQIRVWAV 314
>TAF5_DROME (P49846) Transcription initiation factor TFIID subunit 5| (Transcription initiation factor TFIID 85 kDa subunit) (p85) (TAFII-80) Length = 704 Score = 83.6 bits (205), Expect = 3e-16 Identities = 49/138 (35%), Positives = 70/138 (50%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 S S D T LW T S Q GH V+ V F P+ ++A+ S D++V+LW+ +TG+ Sbjct: 509 SCSYDKTARLWA-TDSNQALRVFVGHLSDVDCVQFHPNSNYVATGSSDRTVRLWDNMTGQ 567 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 V GH V +++SA R L SGS D + +WD+ L L H V + +S Sbjct: 568 SVRLMTGHKGSVSSLAFSACGRYLASGSVDHNIIIWDLSNGSLVTTLLRHTSTVTTITFS 627 Query: 175 PDGEKVVSGGKDRALKLW 122 DG + + G D L LW Sbjct: 628 RDGTVLAAAGLDNNLTLW 645 Score = 71.6 bits (174), Expect = 1e-12 Identities = 40/138 (28%), Positives = 71/138 (51%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 S S+D T+ LW ++ GH V V F+P G + S S+DK+ +LW + + Sbjct: 467 SCSEDSTIRLWS-LLTWSCVVTYRGHVYPVWDVRFAPHGYYFVSCSYDKTARLWATDSNQ 525 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 + F GH++DV + + +S + +GS D T+++WD + + + GH V ++ +S Sbjct: 526 ALRVFVGHLSDVDCVQFHPNSNYVATGSSDRTVRLWDNMTGQSVRLMTGHKGSVSSLAFS 585 Query: 175 PDGEKVVSGGKDRALKLW 122 G + SG D + +W Sbjct: 586 ACGRYLASGSVDHNIIIW 603 Score = 71.6 bits (174), Expect = 1e-12 Identities = 35/118 (29%), Positives = 60/118 (50%) Frame = -2 Query: 469 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 290 + GH V F+P+ L S S D +++LW+ +T V +RGHV V+ + ++ Sbjct: 446 LMGHTGPVYRCAFAPEMNLLLSCSEDSTIRLWSLLTWSCVVTYRGHVYPVWDVRFAPHGY 505 Query: 289 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLWMN 116 +S S D T ++W + + + GH +V V + P+ V +G DR ++LW N Sbjct: 506 YFVSCSYDKTARLWATDSNQALRVFVGHLSDVDCVQFHPNSNYVATGSSDRTVRLWDN 563 Score = 63.9 bits (154), Expect = 3e-10 Identities = 34/97 (35%), Positives = 55/97 (56%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 +GS D T+ LW+ ++ Q MTGH+ V+ + FS G++LAS S D ++ +W+ G Sbjct: 551 TGSSDRTVRLWD-NMTGQSVRLMTGHKGSVSSLAFSACGRYLASGSVDHNIIIWDLSNGS 609 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD 245 VT H + V I++S D +L + D+ L +WD Sbjct: 610 LVTTLLRHTSTVTTITFSRDGTVLAAAGLDNNLTLWD 646 Score = 55.5 bits (132), Expect = 9e-08 Identities = 29/97 (29%), Positives = 51/97 (52%) Frame = -2 Query: 412 LASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRAR 233 L S D +V++ + +G+ + GH VY+ +++ + LLLS S+DST+++W + Sbjct: 423 LDKESADINVRMLDDRSGEVTRSLMGHTGPVYRCAFAPEMNLLLSCSEDSTIRLWSLLTW 482 Query: 232 KLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 GH V+ V ++P G VS D+ +LW Sbjct: 483 SCVVTYRGHVYPVWDVRFAPHGYYFVSCSYDKTARLW 519
>GBLP_TOBAC (P49026) Guanine nucleotide-binding protein beta subunit-like| protein Length = 326 Score = 83.2 bits (204), Expect = 4e-16 Identities = 47/146 (32%), Positives = 77/146 (52%), Gaps = 8/146 (5%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQ----PKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNG 368 + S D ++ +W T P+ R+TGH V V S DG + S S+D ++LW+ Sbjct: 34 TSSRDKSIIVWSITKDGPQYGVPRRRLTGHGHFVQDVVLSSDGMFALSGSWDGELRLWDL 93 Query: 367 ITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDI--RARKLKQDLPGHADEV 194 G F GH DV +++S D+R ++S S+D ++++W+ + QD H+D V Sbjct: 94 QAGTTARRFVGHTKDVLSVAFSVDNRQIVSASRDKSIRLWNTLGECKYTIQDGDSHSDWV 153 Query: 193 YAVDWSPDG--EKVVSGGKDRALKLW 122 V +SP+ +VSG DR +K+W Sbjct: 154 SCVRFSPNNLQPTIVSGSWDRTVKIW 179 Score = 76.6 bits (187), Expect = 4e-14 Identities = 53/142 (37%), Positives = 73/142 (51%), Gaps = 4/142 (2%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SGS D + LW+ + R GH K V V FS D + + SAS DKS++LWN + Sbjct: 81 SGSWDGELRLWDLQAGTTAR-RFVGHTKDVLSVAFSVDNRQIVSASRDKSIRLWNTLGEC 139 Query: 355 FVTAFRG--HVADVYQISWSADSR--LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYA 188 T G H V + +S ++ ++SGS D T+K+W++ KL+ L GH V Sbjct: 140 KYTIQDGDSHSDWVSCVRFSPNNLQPTIVSGSWDRTVKIWNLTNCKLRLTLAGHTGYVNT 199 Query: 187 VDWSPDGEKVVSGGKDRALKLW 122 SPDG SGGKD + LW Sbjct: 200 PAVSPDGSLCASGGKDGVILLW 221 Score = 57.4 bits (137), Expect = 2e-08 Identities = 42/156 (26%), Positives = 72/156 (46%), Gaps = 18/156 (11%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SGS D T+ +W T K + + GH VN SPDG AS D + LW+ GK Sbjct: 169 SGSWDRTVKIWNLTNCKL-RLTLAGHTGYVNTPAVSPDGSLCASGGKDGVILLWDLAEGK 227 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLP------------ 212 + + + ++ + +S + R L + +S++K+WD+ ++ + DL Sbjct: 228 KLYSLESG-SIIHSLCFSPN-RYWLCAATESSIKIWDLESKSIVDDLKVDLKQESEMSSE 285 Query: 211 ----GHADEVY--AVDWSPDGEKVVSGGKDRALKLW 122 G +Y ++ WS DG + SG D +++W Sbjct: 286 GTASGKNKVIYCTSLSWSADGSTLFSGYTDGLIRVW 321 Score = 48.9 bits (115), Expect = 9e-06 Identities = 39/142 (27%), Positives = 65/142 (45%), Gaps = 4/142 (2%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTG--HQKVVNHVYFSPDG--QWLASASFDKSVKLWNG 368 S S D ++ LW T+ + G H V+ V FSP+ + S S+D++VK+WN Sbjct: 123 SASRDKSIRLWN-TLGECKYTIQDGDSHSDWVSCVRFSPNNLQPTIVSGSWDRTVKIWNL 181 Query: 367 ITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYA 188 K GH V + S D L SG KD + +WD+ K L +++ Sbjct: 182 TNCKLRLTLAGHTGYVNTPAVSPDGSLCASGGKDGVILLWDLAEGKKLYSLES-GSIIHS 240 Query: 187 VDWSPDGEKVVSGGKDRALKLW 122 + +SP+ + + ++K+W Sbjct: 241 LCFSPN-RYWLCAATESSIKIW 261 Score = 45.1 bits (105), Expect = 1e-04 Identities = 29/116 (25%), Positives = 53/116 (45%), Gaps = 18/116 (15%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWN----- 371 SG D + LW+ K+ + +G +++ + FSP+ WL +A+ + S+K+W+ Sbjct: 211 SGGKDGVILLWDLAEGKKLYSLESG--SIIHSLCFSPNRYWLCAAT-ESSIKIWDLESKS 267 Query: 370 -------------GITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDI 242 ++ + + + V +SWSAD L SG D ++VW I Sbjct: 268 IVDDLKVDLKQESEMSSEGTASGKNKVIYCTSLSWSADGSTLFSGYTDGLIRVWGI 323
>RCO1_NEUCR (P78706) Transcriptional repressor rco-1| Length = 604 Score = 82.4 bits (202), Expect = 7e-16 Identities = 48/141 (34%), Positives = 85/141 (60%), Gaps = 3/141 (2%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 +G++D + +W+ S+ + GH++ + + FS DG+ +AS S D++V+LW+ TG+ Sbjct: 361 TGAEDKLIRVWDIQ-SRTIRNTFHGHEQDIYSLDFSRDGRTIASGSGDRTVRLWDIETGQ 419 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIR---ARKLKQDLPGHADEVYAV 185 T+ V ++ S D + + +GS D +++VWD+R A +L + GH D VY+V Sbjct: 420 -NTSVLSIEDGVTTVAISPDKQFVAAGSLDKSVRVWDMRGYLAERL-EGPDGHKDSVYSV 477 Query: 184 DWSPDGEKVVSGGKDRALKLW 122 +SPDG +VSG D+ +K+W Sbjct: 478 AFSPDGRNLVSGSLDKTIKMW 498 Score = 68.2 bits (165), Expect = 1e-11 Identities = 46/131 (35%), Positives = 66/131 (50%), Gaps = 17/131 (12%) Frame = -2 Query: 463 GHQKVVNHVYFSPDGQWLASASFDKSVKLWN-----GIT-------GKFVTAFRGHVADV 320 GH+ V V FSPDG+ L S S DK++K+W GI G+ + F GH V Sbjct: 469 GHKDSVYSVAFSPDGRNLVSGSLDKTIKMWELSAPRGIPSSAPPKGGRCIKTFEGHRDFV 528 Query: 319 YQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSP-DGEKVV---- 155 ++ + DS+ +LSGSKD ++ WD R + L GH + V +V SP G V Sbjct: 529 LSVALTPDSQWVLSGSKDRGVQFWDPRTGHTQLMLQGHKNSVISVAPSPVTGPNGVGYFA 588 Query: 154 SGGKDRALKLW 122 +G D ++W Sbjct: 589 TGSGDMRARIW 599
>KTNB1_ARATH (Q8H0T9) Katanin p80 WD40-containing subunit B1 homolog 1| Length = 837 Score = 82.0 bits (201), Expect = 9e-16 Identities = 41/138 (29%), Positives = 76/138 (55%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 +G+ T+ LW+ +K + +TGH+ V F P G++ AS S D ++K+W+ Sbjct: 76 AGAASGTIKLWDLEEAKIVRT-LTGHRSNCISVDFHPFGEFFASGSLDTNLKIWDIRKKG 134 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 + ++GH V + ++ D R ++SG +D+ +KVWD+ A KL + H ++ ++D+ Sbjct: 135 CIHTYKGHTRGVNVLRFTPDGRWVVSGGEDNIVKVWDLTAGKLLTEFKSHEGQIQSLDFH 194 Query: 175 PDGEKVVSGGKDRALKLW 122 P + +G DR +K W Sbjct: 195 PHEFLLATGSADRTVKFW 212 Score = 75.9 bits (185), Expect = 7e-14 Identities = 44/140 (31%), Positives = 70/140 (50%), Gaps = 2/140 (1%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMT--GHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 362 +G +D + LW I K P A ++ GH ++ V F +A+ + ++KLW+ Sbjct: 34 TGGEDHKVNLW--AIGK-PNAILSLYGHSSGIDSVTFDASEVLVAAGAASGTIKLWDLEE 90 Query: 361 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 182 K V GH ++ + + SGS D+ LK+WDIR + GH V + Sbjct: 91 AKIVRTLTGHRSNCISVDFHPFGEFFASGSLDTNLKIWDIRKKGCIHTYKGHTRGVNVLR 150 Query: 181 WSPDGEKVVSGGKDRALKLW 122 ++PDG VVSGG+D +K+W Sbjct: 151 FTPDGRWVVSGGEDNIVKVW 170 Score = 74.7 bits (182), Expect = 2e-13 Identities = 41/129 (31%), Positives = 65/129 (50%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SGS D + +W+ K GH + VN + F+PDG+W+ S D VK+W+ GK Sbjct: 118 SGSLDTNLKIWDIR-KKGCIHTYKGHTRGVNVLRFTPDGRWVVSGGEDNIVKVWDLTAGK 176 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 +T F+ H + + + LL +GS D T+K WD+ +L V + ++ Sbjct: 177 LLTEFKSHEGQIQSLDFHPHEFLLATGSADRTVKFWDLETFELIGSGGPETAGVRCLSFN 236 Query: 175 PDGEKVVSG 149 PDG+ V+ G Sbjct: 237 PDGKTVLCG 245 Score = 60.5 bits (145), Expect = 3e-09 Identities = 29/97 (29%), Positives = 48/97 (49%) Frame = -2 Query: 412 LASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRAR 233 L + D V LW + + GH + + +++ A L+ +G+ T+K+WD+ Sbjct: 32 LVTGGEDHKVNLWAIGKPNAILSLYGHSSGIDSVTFDASEVLVAAGAASGTIKLWDLEEA 91 Query: 232 KLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 K+ + L GH +VD+ P GE SG D LK+W Sbjct: 92 KIVRTLTGHRSNCISVDFHPFGEFFASGSLDTNLKIW 128 Score = 38.9 bits (89), Expect = 0.009 Identities = 26/96 (27%), Positives = 49/96 (51%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SG +D + +W+ T K H+ + + F P LA+ S D++VK W+ T + Sbjct: 160 SGGEDNIVKVWDLTAGKL-LTEFKSHEGQIQSLDFHPHEFLLATGSADRTVKFWDLETFE 218 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVW 248 + + A V +S++ D + +L G ++S LK++ Sbjct: 219 LIGSGGPETAGVRCLSFNPDGKTVLCGLQES-LKIF 253
>PRP4_ARATH (O22212) U4/U6 small nuclear ribonucleoprotein PRP4-like protein| Length = 554 Score = 81.6 bits (200), Expect = 1e-15 Identities = 40/114 (35%), Positives = 63/114 (55%) Frame = -2 Query: 463 GHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLL 284 GH + V F P G++L + S+DK+ +LW+ TG + GH VY I++ D L Sbjct: 337 GHLDRLARVAFHPSGKYLGTTSYDKTWRLWDINTGAELLLQEGHSRSVYGIAFQQDGALA 396 Query: 283 LSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 S DS +VWD+R + GH V++V++SP+G + SGG+D ++W Sbjct: 397 ASCGLDSLARVWDLRTGRSILVFQGHIKPVFSVNFSPNGYHLASGGEDNQCRIW 450 Score = 75.9 bits (185), Expect = 7e-14 Identities = 40/137 (29%), Positives = 70/137 (51%), Gaps = 1/137 (0%) Frame = -2 Query: 529 SDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFV 350 S D T LW+ + + GH + V + F DG AS D ++W+ TG+ + Sbjct: 358 SYDKTWRLWDINTGAELLLQ-EGHSRSVYGIAFQQDGALAASCGLDSLARVWDLRTGRSI 416 Query: 349 TAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSP- 173 F+GH+ V+ +++S + L SG +D+ ++WD+R RK +P HA+ V V + P Sbjct: 417 LVFQGHIKPVFSVNFSPNGYHLASGGEDNQCRIWDLRMRKSLYIIPAHANLVSQVKYEPQ 476 Query: 172 DGEKVVSGGKDRALKLW 122 +G + + D + +W Sbjct: 477 EGYFLATASYDMKVNIW 493 Score = 65.9 bits (159), Expect = 7e-11 Identities = 41/131 (31%), Positives = 64/131 (48%), Gaps = 2/131 (1%) Frame = -2 Query: 508 LWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHV 329 LWE A + H++ V FSP LA+AS D++ KLW G + F GH+ Sbjct: 281 LWEMPQVTNTIAVLKDHKERATDVVFSPVDDCLATASADRTAKLWK-TDGTLLQTFEGHL 339 Query: 328 ADVYQISWSADSRLLLSGSKDSTLKVWDIR--ARKLKQDLPGHADEVYAVDWSPDGEKVV 155 + ++++ + L + S D T ++WDI A L Q+ GH+ VY + + DG Sbjct: 340 DRLARVAFHPSGKYLGTTSYDKTWRLWDINTGAELLLQE--GHSRSVYGIAFQQDGALAA 397 Query: 154 SGGKDRALKLW 122 S G D ++W Sbjct: 398 SCGLDSLARVW 408 Score = 55.1 bits (131), Expect = 1e-07 Identities = 30/97 (30%), Positives = 52/97 (53%), Gaps = 1/97 (1%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSP-DGQWLASASFDKSVKLWNGITG 359 SG +D +W+ + K + H +V+ V + P +G +LA+AS+D V +W+G Sbjct: 440 SGGEDNQCRIWDLRMRKSLYI-IPAHANLVSQVKYEPQEGYFLATASYDMKVNIWSGRDF 498 Query: 358 KFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVW 248 V + GH + V + +ADS + + S D T+K+W Sbjct: 499 SLVKSLAGHESKVASLDITADSSCIATVSHDRTIKLW 535 Score = 43.9 bits (102), Expect = 3e-04 Identities = 31/116 (26%), Positives = 49/116 (42%), Gaps = 2/116 (1%) Frame = -2 Query: 463 GHQKVVNHVYFSPDGQWLASASFDKSVKLWN--GITGKFVTAFRGHVADVYQISWSADSR 290 G + + FS DG+ LA+ S KLW +T + + H + +S Sbjct: 253 GDDRPLTGCSFSRDGKILATCSLSGVTKLWEMPQVTNT-IAVLKDHKERATDVVFSPVDD 311 Query: 289 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 L + S D T K+W L Q GH D + V + P G+ + + D+ +LW Sbjct: 312 CLATASADRTAKLWKTDG-TLLQTFEGHLDRLARVAFHPSGKYLGTTSYDKTWRLW 366
>TUP12_SCHPO (Q9UUG8) Transcriptional repressor tup12| Length = 586 Score = 81.6 bits (200), Expect = 1e-15 Identities = 53/190 (27%), Positives = 89/190 (46%), Gaps = 52/190 (27%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLW------ 374 +G +D + +W+ K+ +TGH++ + + FS DG+ L S S D++V LW Sbjct: 351 TGVEDQQIRIWD-IAQKRVYRLLTGHEQEIYSLDFSKDGKTLVSGSGDRTVCLWDVEAGE 409 Query: 373 --------NGIT-------GKFVTA-------------------FRGHVADVYQISWSAD 296 +G+T G+F+ A GH VY +++S D Sbjct: 410 QKLILHTDDGVTTVMFSPDGQFIAAGSLDKVIRIWTSSGTLVEQLHGHEESVYSVAFSPD 469 Query: 295 SRLLLSGSKDSTLKVWDIRARK------------LKQDLPGHADEVYAVDWSPDGEKVVS 152 + L+SGS D+T+K+W+++ KQ GH D + +V SPDG+ ++S Sbjct: 470 GKYLVSGSLDNTIKLWELQCVSNVAPSMYKEGGICKQTFTGHKDFILSVTVSPDGKWIIS 529 Query: 151 GGKDRALKLW 122 G KDR ++ W Sbjct: 530 GSKDRTIQFW 539 Score = 80.1 bits (196), Expect = 4e-15 Identities = 45/133 (33%), Positives = 80/133 (60%), Gaps = 6/133 (4%) Frame = -2 Query: 502 EPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVA- 326 EP IS Q + H V+ +V FS DG++LA+ +++ ++N TGK +T + + Sbjct: 273 EPPISVQLLHTLE-HTSVICYVRFSADGKFLATGC-NRAAMVFNVETGKLITLLQEESSK 330 Query: 325 ---DVY--QISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEK 161 D+Y +++S D + L +G +D +++WDI +++ + L GH E+Y++D+S DG+ Sbjct: 331 REGDLYVRSVAFSPDGKYLATGVEDQQIRIWDIAQKRVYRLLTGHEQEIYSLDFSKDGKT 390 Query: 160 VVSGGKDRALKLW 122 +VSG DR + LW Sbjct: 391 LVSGSGDRTVCLW 403 Score = 79.0 bits (193), Expect = 8e-15 Identities = 38/110 (34%), Positives = 66/110 (60%), Gaps = 1/110 (0%) Frame = -2 Query: 448 VNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSK 269 V V FSPDG++LA+ D+ +++W+ + GH ++Y + +S D + L+SGS Sbjct: 337 VRSVAFSPDGKYLATGVEDQQIRIWDIAQKRVYRLLTGHEQEIYSLDFSKDGKTLVSGSG 396 Query: 268 DSTLKVWDIRARKLKQDLPGHADE-VYAVDWSPDGEKVVSGGKDRALKLW 122 D T+ +WD+ A + K L H D+ V V +SPDG+ + +G D+ +++W Sbjct: 397 DRTVCLWDVEAGEQKLIL--HTDDGVTTVMFSPDGQFIAAGSLDKVIRIW 444 Score = 74.3 bits (181), Expect = 2e-13 Identities = 47/153 (30%), Positives = 75/153 (49%), Gaps = 15/153 (9%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWN----- 371 +GS D + +W T S ++ GH++ V V FSPDG++L S S D ++KLW Sbjct: 434 AGSLDKVIRIW--TSSGTLVEQLHGHEESVYSVAFSPDGKYLVSGSLDNTIKLWELQCVS 491 Query: 370 ----------GITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQ 221 GI + F GH + ++ S D + ++SGSKD T++ W + + Sbjct: 492 NVAPSMYKEGGICKQ---TFTGHKDFILSVTVSPDGKWIISGSKDRTIQFWSPDSPHSQL 548 Query: 220 DLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 L GH + V +V SP+G +G D ++W Sbjct: 549 TLQGHNNSVISVAVSPNGHCFATGSGDLRARIW 581 Score = 35.4 bits (80), Expect = 0.10 Identities = 19/55 (34%), Positives = 27/55 (49%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWN 371 SGS D T+ W P S + + GH V V SP+G A+ S D ++W+ Sbjct: 529 SGSKDRTIQFWSPD-SPHSQLTLQGHNNSVISVAVSPNGHCFATGSGDLRARIWS 582
>GBLP_ORYSA (P49027) Guanine nucleotide-binding protein beta subunit-like| protein (GPB-LR) (RWD) Length = 334 Score = 81.6 bits (200), Expect = 1e-15 Identities = 55/146 (37%), Positives = 77/146 (52%), Gaps = 8/146 (5%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGI--- 365 SGS D + LW+ + + R GH K V V FS D + + SAS D+++KLWN + Sbjct: 92 SGSWDGELRLWDLSTGVTTR-RFVGHDKDVLSVAFSVDNRQIVSASRDRTIKLWNTLGEC 150 Query: 364 ---TGKFVTAFRGHVADVYQISWSADS--RLLLSGSKDSTLKVWDIRARKLKQDLPGHAD 200 G + GH V + +S ++ ++SGS D T+KVW++ KL+ +L GH Sbjct: 151 KYTIGGDLGGGEGHNGWVSCVRFSPNTFQPTIVSGSWDRTVKVWNLTNCKLRCNLEGHGG 210 Query: 199 EVYAVDWSPDGEKVVSGGKDRALKLW 122 V AV SPDG SGGKD LW Sbjct: 211 YVNAVAVSPDGSLCASGGKDGVTLLW 236 Score = 80.1 bits (196), Expect = 4e-15 Identities = 53/159 (33%), Positives = 79/159 (49%), Gaps = 21/159 (13%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQ-------------PKARMTGHQKVVNHVYFSPDGQWLASASF 395 S S D ++ +W+ T Q P R+TGH V V S DGQ+ S S+ Sbjct: 36 SSSRDKSLLVWDLTNPVQNVGEGAGASEYGVPFRRLTGHSHFVQDVVLSSDGQFALSGSW 95 Query: 394 DKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRAR---KLK 224 D ++LW+ TG F GH DV +++S D+R ++S S+D T+K+W+ + Sbjct: 96 DGELRLWDLSTGVTTRRFVGHDKDVLSVAFSVDNRQIVSASRDRTIKLWNTLGECKYTIG 155 Query: 223 QDL---PGHADEVYAVDWSPD--GEKVVSGGKDRALKLW 122 DL GH V V +SP+ +VSG DR +K+W Sbjct: 156 GDLGGGEGHNGWVSCVRFSPNTFQPTIVSGSWDRTVKVW 194 Score = 57.8 bits (138), Expect = 2e-08 Identities = 41/145 (28%), Positives = 75/145 (51%), Gaps = 7/145 (4%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SGS D T+ +W T K + + GH VN V SPDG AS D LW+ GK Sbjct: 184 SGSWDRTVKVWNLTNCKL-RCNLEGHGGYVNAVAVSPDGSLCASGGKDGVTLLWDLAEGK 242 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDL----PGHADEVY- 191 + + + ++ + +S + L + ++DS +K+WD+ ++ + QDL P +++ Sbjct: 243 RLYSLDAG-SIIHSLCFSPNRYWLCAATQDS-IKIWDLESKHIVQDLKPEIPVSKNQMLY 300 Query: 190 --AVDWSPDGEKVVSGGKDRALKLW 122 +++WS DG + +G D ++++ Sbjct: 301 CTSLNWSADGSTLYAGYTDGTIRIY 325 Score = 50.1 bits (118), Expect = 4e-06 Identities = 34/116 (29%), Positives = 57/116 (49%), Gaps = 2/116 (1%) Frame = -2 Query: 463 GHQKVVNHVYFSPDG--QWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 290 GH V+ V FSP+ + S S+D++VK+WN K GH V ++ S D Sbjct: 163 GHNGWVSCVRFSPNTFQPTIVSGSWDRTVKVWNLTNCKLRCNLEGHGGYVNAVAVSPDGS 222 Query: 289 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 L SG KD +WD+ K L ++++ +SP+ + + +D ++K+W Sbjct: 223 LCASGGKDGVTLLWDLAEGKRLYSLDA-GSIIHSLCFSPNRYWLCAATQD-SIKIW 276 Score = 42.0 bits (97), Expect = 0.001 Identities = 27/106 (25%), Positives = 51/106 (48%), Gaps = 8/106 (7%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SG D LW+ K+ + G +++ + FSP+ WL +A+ D S+K+W+ + K Sbjct: 226 SGGKDGVTLLWDLAEGKRLYSLDAG--SIIHSLCFSPNRYWLCAATQD-SIKIWD-LESK 281 Query: 355 FVT--------AFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDI 242 + + + ++WSAD L +G D T++++ I Sbjct: 282 HIVQDLKPEIPVSKNQMLYCTSLNWSADGSTLYAGYTDGTIRIYKI 327 Score = 33.5 bits (75), Expect = 0.38 Identities = 28/87 (32%), Positives = 40/87 (45%), Gaps = 15/87 (17%) Frame = -2 Query: 337 GHVADVYQISWSAD-SRLLLSGSKDSTLKVWDIR---------ARKLKQDLP-----GHA 203 GH V I+ D S ++S S+D +L VWD+ A + +P GH+ Sbjct: 16 GHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPVQNVGEGAGASEYGVPFRRLTGHS 75 Query: 202 DEVYAVDWSPDGEKVVSGGKDRALKLW 122 V V S DG+ +SG D L+LW Sbjct: 76 HFVQDVVLSSDGQFALSGSWDGELRLW 102
>TUP11_SCHPO (Q09715) Transcriptional repressor tup11| Length = 614 Score = 81.3 bits (199), Expect = 2e-15 Identities = 49/149 (32%), Positives = 77/149 (51%), Gaps = 12/149 (8%) Frame = -2 Query: 532 GSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWN------ 371 GS D + +W ++S R+ GH++ V + FSPD L S S DK++K+W Sbjct: 461 GSLDQIIRVW--SVSGTLVERLEGHKESVYSIAFSPDSSILLSGSLDKTIKVWELQATRS 518 Query: 370 -GIT-----GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPG 209 G++ G + GH V ++ S DSR LSGSKD +++ WD++ + G Sbjct: 519 VGLSAIKPEGICKATYTGHTDFVLSVAVSPDSRWGLSGSKDRSMQFWDLQTGQSYLTCQG 578 Query: 208 HADEVYAVDWSPDGEKVVSGGKDRALKLW 122 H + V +V +SPDG + SG D ++W Sbjct: 579 HKNSVISVCFSPDGRQFASGSGDLRARIW 607 Score = 79.7 bits (195), Expect = 5e-15 Identities = 54/190 (28%), Positives = 87/190 (45%), Gaps = 52/190 (27%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLW------ 374 +G++D + LW+ + K + +GH++ + + FS +G+++ S S D++ +LW Sbjct: 377 TGTEDRQIKLWDLSTQKV-RYVFSGHEQDIYSLDFSHNGRFIVSGSGDRTARLWDVETGQ 435 Query: 373 --------NGIT--------------------------GKFVTAFRGHVADVYQISWSAD 296 NG+T G V GH VY I++S D Sbjct: 436 CILKLEIENGVTAIAISPNDQFIAVGSLDQIIRVWSVSGTLVERLEGHKESVYSIAFSPD 495 Query: 295 SRLLLSGSKDSTLKVWDIRARK------------LKQDLPGHADEVYAVDWSPDGEKVVS 152 S +LLSGS D T+KVW+++A + K GH D V +V SPD +S Sbjct: 496 SSILLSGSLDKTIKVWELQATRSVGLSAIKPEGICKATYTGHTDFVLSVAVSPDSRWGLS 555 Query: 151 GGKDRALKLW 122 G KDR+++ W Sbjct: 556 GSKDRSMQFW 565 Score = 77.4 bits (189), Expect = 2e-14 Identities = 41/149 (27%), Positives = 69/149 (46%), Gaps = 40/149 (26%) Frame = -2 Query: 448 VNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSK 269 V + FSPDG++L + + D+ +KLW+ T K F GH D+Y + +S + R ++SGS Sbjct: 363 VRTIAFSPDGKYLVTGTEDRQIKLWDLSTQKVRYVFSGHEQDIYSLDFSHNGRFIVSGSG 422 Query: 268 DSTLKVWDIRARK----------------------------------------LKQDLPG 209 D T ++WD+ + L + L G Sbjct: 423 DRTARLWDVETGQCILKLEIENGVTAIAISPNDQFIAVGSLDQIIRVWSVSGTLVERLEG 482 Query: 208 HADEVYAVDWSPDGEKVVSGGKDRALKLW 122 H + VY++ +SPD ++SG D+ +K+W Sbjct: 483 HKESVYSIAFSPDSSILLSGSLDKTIKVW 511 Score = 61.2 bits (147), Expect = 2e-09 Identities = 37/109 (33%), Positives = 52/109 (47%), Gaps = 11/109 (10%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQP-----------KARMTGHQKVVNHVYFSPDGQWLASASFDK 389 SGS D T+ +WE ++ KA TGH V V SPD +W S S D+ Sbjct: 501 SGSLDKTIKVWELQATRSVGLSAIKPEGICKATYTGHTDFVLSVAVSPDSRWGLSGSKDR 560 Query: 388 SVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDI 242 S++ W+ TG+ +GH V + +S D R SGS D ++W I Sbjct: 561 SMQFWDLQTGQSYLTCQGHKNSVISVCFSPDGRQFASGSGDLRARIWSI 609
>GBLP_BRANA (Q39336) Guanine nucleotide-binding protein beta subunit-like| protein Length = 327 Score = 81.3 bits (199), Expect = 2e-15 Identities = 47/147 (31%), Positives = 77/147 (52%), Gaps = 9/147 (6%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQP----KARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNG 368 S S D ++ +W+ T + + R+TGH V V S DGQ+ S S+D ++LW+ Sbjct: 33 SASRDKSIIVWKLTKDDKSYGVRQRRLTGHSHFVEDVVLSSDGQFALSGSWDGELRLWDL 92 Query: 367 ITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRAR---KLKQDLPGHADE 197 G F GH DV +++S D+R ++S S+D T+K+W+ + + GH D Sbjct: 93 AAGVSTRRFVGHTKDVLSVAFSLDNRQIVSASRDRTIKLWNTLGECKYTISEGGEGHRDW 152 Query: 196 VYAVDWSPD--GEKVVSGGKDRALKLW 122 V V +SP+ +VS D+ +K+W Sbjct: 153 VSCVRFSPNTLQPTIVSASCDKTVKVW 179 Score = 57.0 bits (136), Expect = 3e-08 Identities = 44/146 (30%), Positives = 72/146 (49%), Gaps = 8/146 (5%) Frame = -2 Query: 535 SGSDDFTMFLWEP------TISKQPKARMTGHQKVVNHVYFSPDG--QWLASASFDKSVK 380 S S D T+ LW TIS+ + GH+ V+ V FSP+ + SAS DK+VK Sbjct: 122 SASRDRTIKLWNTLGECKYTISEGGE----GHRDWVSCVRFSPNTLQPTIVSASCDKTVK 177 Query: 379 LWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHAD 200 +WN K + GH V ++ S D L SG KD + +WD+ K L ++ Sbjct: 178 VWNLSNCKLRSTLAGHTGYVSTVAVSPDGSLCASGGKDGVVLLWDLAEGKKLYSLEANS- 236 Query: 199 EVYAVDWSPDGEKVVSGGKDRALKLW 122 ++A+ ++P+ + ++ +K+W Sbjct: 237 VIHALCFTPN-RYWLCAATEQGIKIW 261 Score = 53.9 bits (128), Expect = 3e-07 Identities = 42/157 (26%), Positives = 71/157 (45%), Gaps = 19/157 (12%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 S S D T+ +W + K ++ + GH V+ V SPDG AS D V LW+ GK Sbjct: 169 SASCDKTVKVWNLSNCKL-RSTLAGHTGYVSTVAVSPDGSLCASGGKDGVVLLWDLAEGK 227 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARK----LKQDLPGHADE--- 197 + + + V +R L + + +K+WD+ ++ LK DL A++ Sbjct: 228 KLYSLEAN--SVIHALCFTPNRYWLCAATEQGIKIWDLESKTVVEDLKVDLKAEAEKSDG 285 Query: 196 ----------VY--AVDWSPDGEKVVSGGKDRALKLW 122 +Y +++WS DG + SG D +++W Sbjct: 286 SGTAATKRKVIYCTSLNWSADGSTLFSGYTDGVIRVW 322 Score = 41.6 bits (96), Expect = 0.001 Identities = 28/117 (23%), Positives = 50/117 (42%), Gaps = 19/117 (16%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWN----- 371 SG D + LW+ +++ K V++ + F+P+ WL +A+ ++ +K+W+ Sbjct: 211 SGGKDGVVLLWD--LAEGKKLYSLEANSVIHALCFTPNRYWLCAAT-EQGIKIWDLESKT 267 Query: 370 --------------GITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDI 242 G A + V ++WSAD L SG D ++VW I Sbjct: 268 VVEDLKVDLKAEAEKSDGSGTAATKRKVIYCTSLNWSADGSTLFSGYTDGVIRVWGI 324
>SPG16_HUMAN (Q8N0X2) Sperm-associated antigen 16 protein (PF20 protein homolog)| Length = 631 Score = 81.3 bits (199), Expect = 2e-15 Identities = 36/114 (31%), Positives = 61/114 (53%) Frame = -2 Query: 463 GHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLL 284 GH ++ F P G LA++S D +VKLW+ TG + F GH V+ +W + + Sbjct: 392 GHTDWLSDCCFHPSGDKLATSSGDTTVKLWDLCTGDCILTFEGHSRAVWSCTWHSCGNFV 451 Query: 283 LSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 S S D T K+WD+ + + + L GH D V ++++ P +++ D+ L +W Sbjct: 452 ASSSLDKTSKIWDVNSERCRCTLYGHTDSVNSIEFFPFSNTLLTSSADKTLSIW 505 Score = 63.2 bits (152), Expect = 5e-10 Identities = 40/138 (28%), Positives = 61/138 (44%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 + S D T+ LW+ + GH + V + G ++AS+S DK+ K+W+ + + Sbjct: 411 TSSGDTTVKLWD-LCTGDCILTFEGHSRAVWSCTWHSCGNFVASSSLDKTSKIWDVNSER 469 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 GH V I + S LL+ S D TL +WD R +Q L GH + + Sbjct: 470 CRCTLYGHTDSVNSIEFFPFSNTLLTSSADKTLSIWDARTGICEQSLYGHMHSINDAIFD 529 Query: 175 PDGEKVVSGGKDRALKLW 122 P G + S KLW Sbjct: 530 PRGHMIASCDACGVTKLW 547 Score = 54.3 bits (129), Expect = 2e-07 Identities = 43/179 (24%), Positives = 69/179 (38%), Gaps = 41/179 (22%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 S S D T +W+ S++ + + GH VN + F P L ++S DK++ +W+ TG Sbjct: 453 SSSLDKTSKIWDVN-SERCRCTLYGHTDSVNSIEFFPFSNTLLTSSADKTLSIWDARTGI 511 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIR--------------------- 239 + GH+ + + ++ S K+WD R Sbjct: 512 CEQSLYGHMHSINDAIFDPRGHMIASCDACGVTKLWDFRKLLPIVSIDIGPSPGNEVNFD 571 Query: 238 --ARKLKQ------------------DLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 R L Q L GH +E + V +S DGE + SGG D ++ W Sbjct: 572 SSGRVLAQASGNGVIHLLDLKSGEIHKLMGHENEAHTVVFSHDGEILFSGGSDGTVRTW 630 Score = 29.3 bits (64), Expect = 7.3 Identities = 12/34 (35%), Positives = 20/34 (58%) Frame = -2 Query: 472 RMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWN 371 ++ GH+ + V FS DG+ L S D +V+ W+ Sbjct: 598 KLMGHENEAHTVVFSHDGEILFSGGSDGTVRTWS 631
>PRP4_PONPY (Q5NVD0) U4/U6 small nuclear ribonucleoprotein Prp4 (U4/U6 snRNP 60| kDa protein) (WD splicing factor Prp4) Length = 521 Score = 81.3 bits (199), Expect = 2e-15 Identities = 42/134 (31%), Positives = 71/134 (52%) Frame = -2 Query: 523 DFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTA 344 D ++ LW S +P A + GH V V + P G++L + +D+S +LW+ + + Sbjct: 301 DGSVKLWSLD-SDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQEEILH 359 Query: 343 FRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGE 164 GH VY I++ D L +G D+ +VWD+R + L GH E+Y +++SP+G Sbjct: 360 QEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPNGY 419 Query: 163 KVVSGGKDRALKLW 122 + +G D K+W Sbjct: 420 HIATGSGDNTCKVW 433 Score = 72.4 bits (176), Expect = 7e-13 Identities = 35/115 (30%), Positives = 60/115 (52%), Gaps = 1/115 (0%) Frame = -2 Query: 463 GHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLL 284 GH V + F DG + D ++W+ TG+ + GH+ ++Y I++S + + Sbjct: 362 GHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPNGYHI 421 Query: 283 LSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSP-DGEKVVSGGKDRALKLW 122 +GS D+T KVWD+R R+ +P H + V V + P G +++G D K+W Sbjct: 422 ATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHGNFLLTGAYDNTAKIW 476 Score = 63.2 bits (152), Expect = 5e-10 Identities = 36/118 (30%), Positives = 58/118 (49%), Gaps = 1/118 (0%) Frame = -2 Query: 469 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSA-DS 293 + GH K + + FSP+G +A+ S D + K+W+ + V H V + + Sbjct: 402 LEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHG 461 Query: 292 RLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLWM 119 LL+G+ D+T K+W + L GH +V +D S DG+ + + DR KLWM Sbjct: 462 NFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLIATCSYDRTFKLWM 519 Score = 57.8 bits (138), Expect = 2e-08 Identities = 36/120 (30%), Positives = 58/120 (48%) Frame = -2 Query: 481 PKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWS 302 PK+ ++ QK VN LAS + D SVKLW+ + + V GH V ++ W Sbjct: 282 PKSTVSLDQKDVN----------LASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWH 331 Query: 301 ADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 R L + D + ++WD+ A++ GH+ VY + + DG +GG D ++W Sbjct: 332 PSGRFLGTTCYDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVW 391 Score = 55.5 bits (132), Expect = 9e-08 Identities = 33/122 (27%), Positives = 59/122 (48%), Gaps = 8/122 (6%) Frame = -2 Query: 463 GHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRL- 287 G + +++ +FSP+ + LA+A + KLW+ + RGH +V I + S + Sbjct: 228 GDDRPISYCHFSPNSKMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKSTVS 287 Query: 286 -------LLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALK 128 L S + D ++K+W + + + D+ GH V V W P G + + DR+ + Sbjct: 288 LDQKDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWR 347 Query: 127 LW 122 LW Sbjct: 348 LW 349 Score = 34.7 bits (78), Expect = 0.17 Identities = 18/54 (33%), Positives = 29/54 (53%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLW 374 +G+ D T +W P + GH+ V + S DGQ +A+ S+D++ KLW Sbjct: 466 TGAYDNTAKIWTHP-GWSPLKTLAGHEGKVMGLDISSDGQLIATCSYDRTFKLW 518
>PRP4_MOUSE (Q9DAW6) U4/U6 small nuclear ribonucleoprotein Prp4 (U4/U6 snRNP 60| kDa protein) (WD splicing factor Prp4) Length = 521 Score = 81.3 bits (199), Expect = 2e-15 Identities = 42/134 (31%), Positives = 71/134 (52%) Frame = -2 Query: 523 DFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTA 344 D ++ LW S +P A + GH V V + P G++L + +D+S +LW+ + + Sbjct: 301 DGSVKLWSLD-SDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQEEILH 359 Query: 343 FRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGE 164 GH VY I++ D L +G D+ +VWD+R + L GH E+Y +++SP+G Sbjct: 360 QEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPNGY 419 Query: 163 KVVSGGKDRALKLW 122 + +G D K+W Sbjct: 420 HIATGSGDNTCKVW 433 Score = 73.2 bits (178), Expect = 4e-13 Identities = 35/115 (30%), Positives = 61/115 (53%), Gaps = 1/115 (0%) Frame = -2 Query: 463 GHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLL 284 GH V + F DG + D ++W+ TG+ + GH+ ++Y I++S + + Sbjct: 362 GHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPNGYHI 421 Query: 283 LSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSP-DGEKVVSGGKDRALKLW 122 +GS D+T KVWD+R R+ +P H + V V + P G+ +++G D K+W Sbjct: 422 ATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHGDFLLTGAYDNTAKIW 476 Score = 62.4 bits (150), Expect = 8e-10 Identities = 36/118 (30%), Positives = 58/118 (49%), Gaps = 1/118 (0%) Frame = -2 Query: 469 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSA-DS 293 + GH K + + FSP+G +A+ S D + K+W+ + V H V + + Sbjct: 402 LEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHG 461 Query: 292 RLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLWM 119 LL+G+ D+T K+W + L GH +V +D S DG+ + + DR KLWM Sbjct: 462 DFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLIATCSYDRTFKLWM 519 Score = 57.8 bits (138), Expect = 2e-08 Identities = 36/120 (30%), Positives = 58/120 (48%) Frame = -2 Query: 481 PKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWS 302 PK+ ++ QK VN LAS + D SVKLW+ + + V GH V ++ W Sbjct: 282 PKSTVSLDQKDVN----------LASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWH 331 Query: 301 ADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 R L + D + ++WD+ A++ GH+ VY + + DG +GG D ++W Sbjct: 332 PSGRFLGTTCYDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVW 391 Score = 55.5 bits (132), Expect = 9e-08 Identities = 33/122 (27%), Positives = 59/122 (48%), Gaps = 8/122 (6%) Frame = -2 Query: 463 GHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRL- 287 G + +++ +FSP+ + LA+A + KLW+ + RGH +V I + S + Sbjct: 228 GDDRPISYCHFSPNSKMLATACWSGLCKLWSVPDCSLLHTLRGHNTNVGAIVFHPKSTVS 287 Query: 286 -------LLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALK 128 L S + D ++K+W + + + D+ GH V V W P G + + DR+ + Sbjct: 288 LDQKDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWR 347 Query: 127 LW 122 LW Sbjct: 348 LW 349 Score = 34.7 bits (78), Expect = 0.17 Identities = 18/54 (33%), Positives = 29/54 (53%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLW 374 +G+ D T +W P + GH+ V + S DGQ +A+ S+D++ KLW Sbjct: 466 TGAYDNTAKIWTHP-GWSPLKTLAGHEGKVMGLDISSDGQLIATCSYDRTFKLW 518
>PRP4_HUMAN (O43172) U4/U6 small nuclear ribonucleoprotein Prp4 (U4/U6 snRNP 60| kDa protein) (WD splicing factor Prp4) (hPrp4) Length = 522 Score = 81.3 bits (199), Expect = 2e-15 Identities = 42/134 (31%), Positives = 71/134 (52%) Frame = -2 Query: 523 DFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTA 344 D ++ LW S +P A + GH V V + P G++L + +D+S +LW+ + + Sbjct: 302 DGSVKLWSLD-SDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQEEILH 360 Query: 343 FRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGE 164 GH VY I++ D L +G D+ +VWD+R + L GH E+Y +++SP+G Sbjct: 361 QEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPNGY 420 Query: 163 KVVSGGKDRALKLW 122 + +G D K+W Sbjct: 421 HIATGSGDNTCKVW 434 Score = 72.4 bits (176), Expect = 7e-13 Identities = 35/115 (30%), Positives = 60/115 (52%), Gaps = 1/115 (0%) Frame = -2 Query: 463 GHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLL 284 GH V + F DG + D ++W+ TG+ + GH+ ++Y I++S + + Sbjct: 363 GHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPNGYHI 422 Query: 283 LSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSP-DGEKVVSGGKDRALKLW 122 +GS D+T KVWD+R R+ +P H + V V + P G +++G D K+W Sbjct: 423 ATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHGNFLLTGAYDNTAKIW 477 Score = 63.2 bits (152), Expect = 5e-10 Identities = 36/118 (30%), Positives = 58/118 (49%), Gaps = 1/118 (0%) Frame = -2 Query: 469 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSA-DS 293 + GH K + + FSP+G +A+ S D + K+W+ + V H V + + Sbjct: 403 LEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHG 462 Query: 292 RLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLWM 119 LL+G+ D+T K+W + L GH +V +D S DG+ + + DR KLWM Sbjct: 463 NFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLIATCSYDRTFKLWM 520 Score = 57.0 bits (136), Expect = 3e-08 Identities = 35/124 (28%), Positives = 56/124 (45%), Gaps = 8/124 (6%) Frame = -2 Query: 469 MTGHQKVVNHVYFSPDGQW--------LASASFDKSVKLWNGITGKFVTAFRGHVADVYQ 314 + GH V + F P LAS + D SVKLW+ + + V GH V + Sbjct: 269 LRGHNTNVGAIVFHPKSTVSLDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVAR 328 Query: 313 ISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRA 134 + W R L + D + ++WD+ A++ GH+ VY + + DG +GG D Sbjct: 329 VMWHPSGRFLGTTCYDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAF 388 Query: 133 LKLW 122 ++W Sbjct: 389 GRVW 392 Score = 55.5 bits (132), Expect = 9e-08 Identities = 33/122 (27%), Positives = 59/122 (48%), Gaps = 8/122 (6%) Frame = -2 Query: 463 GHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRL- 287 G + +++ +FSP+ + LA+A + KLW+ + RGH +V I + S + Sbjct: 229 GDDRPISYCHFSPNSKMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKSTVS 288 Query: 286 -------LLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALK 128 L S + D ++K+W + + + D+ GH V V W P G + + DR+ + Sbjct: 289 LDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWR 348 Query: 127 LW 122 LW Sbjct: 349 LW 350 Score = 34.7 bits (78), Expect = 0.17 Identities = 18/54 (33%), Positives = 29/54 (53%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLW 374 +G+ D T +W P + GH+ V + S DGQ +A+ S+D++ KLW Sbjct: 467 TGAYDNTAKIWTHP-GWSPLKTLAGHEGKVMGLDISSDGQLIATCSYDRTFKLW 519
>TUP1_CANAL (P56093) Transcriptional repressor TUP1| Length = 514 Score = 81.3 bits (199), Expect = 2e-15 Identities = 38/109 (34%), Positives = 64/109 (58%) Frame = -2 Query: 448 VNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSK 269 + V FSPDG+ LA+ + DK +++W+ T + + RGH D+Y + + D L+SGS Sbjct: 260 IRSVCFSPDGKLLATGAEDKLIRIWDLSTKRIIKILRGHEQDIYSLDFFPDGDRLVSGSG 319 Query: 268 DSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 D ++++WD+R + L D V V SPDG+ + +G DR +++W Sbjct: 320 DRSVRIWDLRTSQCSLTL-SIEDGVTTVAVSPDGKLIAAGSLDRTVRVW 367 Score = 78.6 bits (192), Expect = 1e-14 Identities = 48/146 (32%), Positives = 81/146 (55%), Gaps = 8/146 (5%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 +G++D + +W+ + + K + GH++ + + F PDG L S S D+SV++W+ T + Sbjct: 274 TGAEDKLIRIWDLSTKRIIKI-LRGHEQDIYSLDFFPDGDRLVSGSGDRSVRIWDLRTSQ 332 Query: 355 FVTAFRGHVAD-VYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLP-------GHAD 200 + D V ++ S D +L+ +GS D T++VWD L + L GH D Sbjct: 333 CSLTLS--IEDGVTTVAVSPDGKLIAAGSLDRTVRVWDSTTGFLVERLDSGNENGNGHED 390 Query: 199 EVYAVDWSPDGEKVVSGGKDRALKLW 122 VY+V +S +GE++ SG DR +KLW Sbjct: 391 SVYSVAFSNNGEQIASGSLDRTVKLW 416 Score = 78.6 bits (192), Expect = 1e-14 Identities = 43/146 (29%), Positives = 82/146 (56%), Gaps = 17/146 (11%) Frame = -2 Query: 508 LWEPTISKQPKARMT---GHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFR 338 L+ P SK M H VV V FS DG+++A+ +K+ +++N TG+ V Sbjct: 182 LYNPAFSKDLDIDMVHSLDHSSVVCCVRFSRDGKFIATGC-NKTTQVFNVTTGELVAKLI 240 Query: 337 GHVA------------DVY--QISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHAD 200 + D+Y + +S D +LL +G++D +++WD+ +++ + L GH Sbjct: 241 DESSNENKDDNTTASGDLYIRSVCFSPDGKLLATGAEDKLIRIWDLSTKRIIKILRGHEQ 300 Query: 199 EVYAVDWSPDGEKVVSGGKDRALKLW 122 ++Y++D+ PDG+++VSG DR++++W Sbjct: 301 DIYSLDFFPDGDRLVSGSGDRSVRIW 326 Score = 57.0 bits (136), Expect = 3e-08 Identities = 45/153 (29%), Positives = 71/153 (46%), Gaps = 15/153 (9%) Frame = -2 Query: 535 SGSDDFTMFLWEPTIS------KQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLW 374 +GS D T+ +W+ T GH+ V V FS +G+ +AS S D++VKLW Sbjct: 357 AGSLDRTVRVWDSTTGFLVERLDSGNENGNGHEDSVYSVAFSNNGEQIASGSLDRTVKLW 416 Query: 373 N--GITGKFVT---AFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPG 209 + G + K T + GH V + + D+ +LSGSKD + WD + L G Sbjct: 417 HLEGKSDKKSTCEVTYIGHKDFVLSVCCTPDNEYILSGSKDRGVIFWDQASGNPLLMLQG 476 Query: 208 HADEVYAVDWSPDGEKV----VSGGKDRALKLW 122 H + V +V S + + +G D ++W Sbjct: 477 HRNSVISVAVSLNSKGTEGIFATGSGDCKARIW 509
>LIS1_CAEEL (Q9NDC9) Lissencephaly-1 homolog (Pronuclear migration abnormal| protein 1) Length = 404 Score = 80.5 bits (197), Expect = 3e-15 Identities = 51/153 (33%), Positives = 73/153 (47%), Gaps = 15/153 (9%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 S S D ++ LW+ + + GH+ V+ V F P G ++ SAS D ++K W+ TG Sbjct: 165 SCSSDLSIKLWDFGQTYDCLKSLKGHEHTVSSVTFLPTGDFVLSASRDHTIKQWDISTGY 224 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 V FRGH V I S D L S S D T+ VW + K L H V V+W+ Sbjct: 225 CVYTFRGHNDWVRMIRISNDGTLFASASLDQTVTVWSFATKSAKLVLRDHEHAVECVEWA 284 Query: 175 PD-------GEK--------VVSGGKDRALKLW 122 PD G++ + SG +DR++K W Sbjct: 285 PDTAYTNVTGQQPEGNSTHILFSGSRDRSIKAW 317 Score = 71.6 bits (174), Expect = 1e-12 Identities = 38/118 (32%), Positives = 63/118 (53%), Gaps = 1/118 (0%) Frame = -2 Query: 472 RMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADS 293 ++TGH+ + V F P +AS S D ++K+W+ TG+ +GH V I+ A Sbjct: 101 KLTGHRLPITRVIFHPLWTIMASCSEDATIKVWDYETGQLERTLKGHTDAVNDIAIDAAG 160 Query: 292 RLLLSGSKDSTLKVWDI-RARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 + L+S S D ++K+WD + + L GH V +V + P G+ V+S +D +K W Sbjct: 161 KQLVSCSSDLSIKLWDFGQTYDCLKSLKGHEHTVSSVTFLPTGDFVLSASRDHTIKQW 218 Score = 68.6 bits (166), Expect = 1e-11 Identities = 43/139 (30%), Positives = 66/139 (47%), Gaps = 1/139 (0%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWN-GITG 359 S S+D T+ +W+ Q + + GH VN + G+ L S S D S+KLW+ G T Sbjct: 123 SCSEDATIKVWDYETG-QLERTLKGHTDAVNDIAIDAAGKQLVSCSSDLSIKLWDFGQTY 181 Query: 358 KFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDW 179 + + +GH V +++ +LS S+D T+K WDI GH D V + Sbjct: 182 DCLKSLKGHEHTVSSVTFLPTGDFVLSASRDHTIKQWDISTGYCVYTFRGHNDWVRMIRI 241 Query: 178 SPDGEKVVSGGKDRALKLW 122 S DG S D+ + +W Sbjct: 242 SNDGTLFASASLDQTVTVW 260 Score = 58.5 bits (140), Expect = 1e-08 Identities = 40/153 (26%), Positives = 69/153 (45%), Gaps = 15/153 (9%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQW---------------LASA 401 S S D T+ +W +K K + H+ V V ++PD + L S Sbjct: 250 SASLDQTVTVWS-FATKSAKLVLRDHEHAVECVEWAPDTAYTNVTGQQPEGNSTHILFSG 308 Query: 400 SFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQ 221 S D+S+K WN TG + H V +++ + L+S + D TL+VW++ A++ + Sbjct: 309 SRDRSIKAWNINTGDVLFTLLAHENWVRGLAFHPKGKYLISVADDKTLRVWELSAQRCMK 368 Query: 220 DLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 + H V V + V++G D + K+W Sbjct: 369 AIEAHEHFVSTVAFHQTSPFVITGSVDMSCKVW 401 Score = 45.8 bits (107), Expect = 7e-05 Identities = 26/99 (26%), Positives = 48/99 (48%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SGS D ++ W + H+ V + F P G++L S + DK++++W + Sbjct: 307 SGSRDRSIKAWNINTG-DVLFTLLAHENWVRGLAFHPKGKYLISVADDKTLRVWELSAQR 365 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIR 239 + A H V +++ S +++GS D + KVW+ R Sbjct: 366 CMKAIEAHEHFVSTVAFHQTSPFVITGSVDMSCKVWECR 404
>EBI_DROME (Q95RJ9) F-box-like/WD repeat protein ebi| Length = 700 Score = 80.1 bits (196), Expect = 4e-15 Identities = 41/130 (31%), Positives = 66/130 (50%), Gaps = 9/130 (6%) Frame = -2 Query: 484 QPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISW 305 +P GH VN + + P GQ LAS S D ++K+W+ + + H ++Y I W Sbjct: 525 EPIKTFKGHTNEVNAIKWCPQGQLLASCSDDMTLKIWSMNRDRCCHDLQAHSKEIYTIKW 584 Query: 304 SAD---------SRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVS 152 S + +L S S DST+++WD+ L H + VY+V +SPDG+ + S Sbjct: 585 SPTGPGTNNPNTNLILASASFDSTVRLWDVERGSCIHTLTKHTEPVYSVAFSPDGKHLAS 644 Query: 151 GGKDRALKLW 122 G D+ + +W Sbjct: 645 GSFDKCVHIW 654 Score = 63.5 bits (153), Expect = 3e-10 Identities = 41/141 (29%), Positives = 64/141 (45%), Gaps = 9/141 (6%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQW---------LASASFDKSV 383 S SDD T+ +W + + H K + + +SP G LASASFD +V Sbjct: 551 SCSDDMTLKIWSMNRDRCCHD-LQAHSKEIYTIKWSPTGPGTNNPNTNLILASASFDSTV 609 Query: 382 KLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHA 203 +LW+ G + H VY +++S D + L SGS D + +W + +L G Sbjct: 610 RLWDVERGSCIHTLTKHTEPVYSVAFSPDGKHLASGSFDKCVHIWSTQTGQLVHSYKG-T 668 Query: 202 DEVYAVDWSPDGEKVVSGGKD 140 ++ V W+ G KV + D Sbjct: 669 GGIFEVCWNSKGTKVGASASD 689 Score = 62.4 bits (150), Expect = 8e-10 Identities = 33/108 (30%), Positives = 50/108 (46%), Gaps = 9/108 (8%) Frame = -2 Query: 418 QWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIR 239 Q AS S D+ + + + + F+GH +V I W +LL S S D TLK+W + Sbjct: 505 QAFASCSTDQRIHVCRLGVNEPIKTFKGHTNEVNAIKWCPQGQLLASCSDDMTLKIWSMN 564 Query: 238 ARKLKQDLPGHADEVYAVDWSPDGEK---------VVSGGKDRALKLW 122 + DL H+ E+Y + WSP G + S D ++LW Sbjct: 565 RDRCCHDLQAHSKEIYTIKWSPTGPGTNNPNTNLILASASFDSTVRLW 612 Score = 58.5 bits (140), Expect = 1e-08 Identities = 29/100 (29%), Positives = 47/100 (47%) Frame = -2 Query: 421 GQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDI 242 G ++ SA DK+ +W+ TG+ F H A + W ++ S S D + V + Sbjct: 463 GNYILSAGVDKTTIIWDASTGQCTQQFAFHSAPALDVDWQT-NQAFASCSTDQRIHVCRL 521 Query: 241 RARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 + + GH +EV A+ W P G+ + S D LK+W Sbjct: 522 GVNEPIKTFKGHTNEVNAIKWCPQGQLLASCSDDMTLKIW 561 Score = 53.1 bits (126), Expect = 5e-07 Identities = 36/135 (26%), Positives = 59/135 (43%), Gaps = 14/135 (10%) Frame = -2 Query: 484 QPKAR-MTGHQKVVNHVYFSPDGQWLASASFDKSVKLW---NGITGKFVTAFRGHV---- 329 + KAR + GH+ V ++P LAS S D + ++W + T R + Sbjct: 345 ESKARVLRGHESEVFICAWNPSRDLLASGSGDSTARIWDMSDANTNSNQLVLRHCIQKGG 404 Query: 328 ------ADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDG 167 DV + W+ D LL +GS D ++W R L L H ++A+ W+ G Sbjct: 405 AEVPSNKDVTSLDWNCDGSLLATGSYDGYARIWKTDGR-LASTLGQHKGPIFALKWNKCG 463 Query: 166 EKVVSGGKDRALKLW 122 ++S G D+ +W Sbjct: 464 NYILSAGVDKTTIIW 478 Score = 33.1 bits (74), Expect = 0.50 Identities = 14/49 (28%), Positives = 26/49 (53%) Frame = -2 Query: 268 DSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 D +++ + +AR L+ GH EV+ W+P + + SG D ++W Sbjct: 338 DENIEIPESKARVLR----GHESEVFICAWNPSRDLLASGSGDSTARIW 382
>LIS1_DROME (Q7KNS3) Lissencephaly-1 homolog (Lissencephaly1) (Dlis1) (DLis-1)| Length = 411 Score = 79.7 bits (195), Expect = 5e-15 Identities = 38/120 (31%), Positives = 70/120 (58%), Gaps = 1/120 (0%) Frame = -2 Query: 478 KARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSA 299 K +TGH+ + V F P + SAS D ++++W+ TG++ + +GH V +++ A Sbjct: 101 KFSLTGHRASITRVIFHPIFALMVSASEDATIRIWDFETGEYERSLKGHTDSVQDVAFDA 160 Query: 298 DSRLLLSGSKDSTLKVWDI-RARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 +LL S S D ++K+WD ++ + + + GH V +V + P G+ V+S +DR +K+W Sbjct: 161 QGKLLASCSADLSIKLWDFQQSYECIKTMHGHDHNVSSVAFVPAGDYVLSASRDRTIKMW 220 Score = 72.0 bits (175), Expect = 1e-12 Identities = 42/158 (26%), Positives = 72/158 (45%), Gaps = 20/158 (12%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 S S D ++ LW+ S + M GH V+ V F P G ++ SAS D+++K+W TG Sbjct: 167 SCSADLSIKLWDFQQSYECIKTMHGHDHNVSSVAFVPAGDYVLSASRDRTIKMWEVATGY 226 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 V + GH V + + + + S D T++VW ++ K +L H V + W+ Sbjct: 227 CVKTYTGHREWVRMVRVHIEGSIFATCSNDQTIRVWLTNSKDCKVELRDHEHTVECIAWA 286 Query: 175 PD--------------------GEKVVSGGKDRALKLW 122 P+ G + SG +D+ +++W Sbjct: 287 PEAAASAINEAAGADNKKGHHQGPFLASGSRDKTIRIW 324 Score = 67.4 bits (163), Expect = 2e-11 Identities = 41/156 (26%), Positives = 75/156 (48%), Gaps = 20/156 (12%) Frame = -2 Query: 529 SDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPD--------------------GQWL 410 S+D T+ +W T SK K + H+ V + ++P+ G +L Sbjct: 254 SNDQTIRVWL-TNSKDCKVELRDHEHTVECIAWAPEAAASAINEAAGADNKKGHHQGPFL 312 Query: 409 ASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARK 230 AS S DK++++W+ G + GH V +++ + L+S S D T++VWD+R ++ Sbjct: 313 ASGSRDKTIRIWDVSVGLCLLTLSGHDNWVRGLAFHPGGKYLVSASDDKTIRVWDLRNKR 372 Query: 229 LKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 + L H ++D+ V+SG D+ +K+W Sbjct: 373 CMKTLYAHQHFCTSIDFHKAHPYVISGSVDQTVKVW 408 Score = 63.5 bits (153), Expect = 3e-10 Identities = 37/140 (26%), Positives = 69/140 (49%), Gaps = 1/140 (0%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITG- 359 S S+D T+ +W+ + ++ + GH V V F G+ LAS S D S+KLW+ Sbjct: 125 SASEDATIRIWDFETGEYERS-LKGHTDSVQDVAFDAQGKLLASCSADLSIKLWDFQQSY 183 Query: 358 KFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDW 179 + + GH +V +++ +LS S+D T+K+W++ + GH + V V Sbjct: 184 ECIKTMHGHDHNVSSVAFVPAGDYVLSASRDRTIKMWEVATGYCVKTYTGHREWVRMVRV 243 Query: 178 SPDGEKVVSGGKDRALKLWM 119 +G + D+ +++W+ Sbjct: 244 HIEGSIFATCSNDQTIRVWL 263 Score = 54.3 bits (129), Expect = 2e-07 Identities = 30/99 (30%), Positives = 52/99 (52%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SGS D T+ +W+ ++ ++GH V + F P G++L SAS DK++++W+ + Sbjct: 314 SGSRDKTIRIWDVSVGLC-LLTLSGHDNWVRGLAFHPGGKYLVSASDDKTIRVWDLRNKR 372 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIR 239 + H I + ++SGS D T+KVW+ R Sbjct: 373 CMKTLYAHQHFCTSIDFHKAHPYVISGSVDQTVKVWECR 411
>GBB1_CAEEL (P17343) Guanine nucleotide-binding protein beta subunit 1| Length = 340 Score = 79.7 bits (195), Expect = 5e-15 Identities = 42/116 (36%), Positives = 63/116 (54%) Frame = -2 Query: 469 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 290 + GH ++ F D Q + ++S D + LW+ TG+ TAF GH DV +S S D R Sbjct: 139 LPGHTGYLSCCRFLDDNQ-IVTSSGDMTCALWDIETGQQCTAFTGHTGDVMSLSLSPDFR 197 Query: 289 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 +SG+ D++ K+WDIR KQ PGH ++ AV + P G +G D +L+ Sbjct: 198 TFISGACDASAKLWDIRDGMCKQTFPGHESDINAVAFFPSGNAFATGSDDATCRLF 253 Score = 59.3 bits (142), Expect = 7e-09 Identities = 41/143 (28%), Positives = 68/143 (47%), Gaps = 5/143 (3%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 + S D T LW+ +Q A TGH V + SPD + S + D S KLW+ G Sbjct: 159 TSSGDMTCALWDIETGQQCTA-FTGHTGDVMSLSLSPDFRTFISGACDASAKLWDIRDGM 217 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADE-----VY 191 F GH +D+ +++ +GS D+T +++DIRA Q+L ++ + + Sbjct: 218 CKQTFPGHESDINAVAFFPSGNAFATGSDDATCRLFDIRA---DQELAMYSHDNIICGIT 274 Query: 190 AVDWSPDGEKVVSGGKDRALKLW 122 +V +S G + +G D +W Sbjct: 275 SVAFSKSGRLLFAGYDDFNCNVW 297 Score = 58.5 bits (140), Expect = 1e-08 Identities = 41/141 (29%), Positives = 64/141 (45%), Gaps = 3/141 (2%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SG+ D + LW+ K GH+ +N V F P G A+ S D + +L++ I Sbjct: 201 SGACDASAKLWDIR-DGMCKQTFPGHESDINAVAFFPSGNAFATGSDDATCRLFD-IRAD 258 Query: 355 FVTAFRGH---VADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAV 185 A H + + +++S RLL +G D VWD ++ L GH + V + Sbjct: 259 QELAMYSHDNIICGITSVAFSKSGRLLFAGYDDFNCNVWDSMRQERAGVLAGHDNRVSCL 318 Query: 184 DWSPDGEKVVSGGKDRALKLW 122 + DG V +G D LK+W Sbjct: 319 GVTEDGMAVCTGSWDSFLKIW 339 Score = 52.4 bits (124), Expect = 8e-07 Identities = 25/73 (34%), Positives = 38/73 (52%) Frame = -2 Query: 340 RGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEK 161 RGH+A +Y + W++DSR L+S S+D L VWD +P + V ++P G Sbjct: 52 RGHLAKIYAMHWASDSRNLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSGSF 111 Query: 160 VVSGGKDRALKLW 122 V GG D ++ Sbjct: 112 VACGGLDNICSIY 124 Score = 42.4 bits (98), Expect = 8e-04 Identities = 28/128 (21%), Positives = 57/128 (44%), Gaps = 4/128 (3%) Frame = -2 Query: 493 ISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQ 314 I + + + GH + ++++ D + L SAS D + +W+ T V A + V Sbjct: 43 IQMRTRRTLRGHLAKIYAMHWASDSRNLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMT 102 Query: 313 ISWSADSRLLLSGSKDSTLKVWDIRAR----KLKQDLPGHADEVYAVDWSPDGEKVVSGG 146 +++ + G D+ ++ ++ R ++ ++LPGH + + D + V S G Sbjct: 103 CAYAPSGSFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIVTSSG 162 Query: 145 KDRALKLW 122 D LW Sbjct: 163 -DMTCALW 169 Score = 39.3 bits (90), Expect = 0.007 Identities = 27/100 (27%), Positives = 46/100 (46%), Gaps = 3/100 (3%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVV---NHVYFSPDGQWLASASFDKSVKLWNGI 365 +GSDD T L++ I + M H ++ V FS G+ L + D + +W+ + Sbjct: 243 TGSDDATCRLFD--IRADQELAMYSHDNIICGITSVAFSKSGRLLFAGYDDFNCNVWDSM 300 Query: 364 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD 245 + GH V + + D + +GS DS LK+W+ Sbjct: 301 RQERAGVLAGHDNRVSCLGVTEDGMAVCTGSWDSFLKIWN 340
>GBB1_CAEBR (Q61ZF6) Guanine nucleotide-binding protein beta subunit 1| Length = 340 Score = 79.7 bits (195), Expect = 5e-15 Identities = 42/116 (36%), Positives = 63/116 (54%) Frame = -2 Query: 469 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 290 + GH ++ F D Q + ++S D + LW+ TG+ TAF GH DV +S S D R Sbjct: 139 LPGHTGYLSCCRFLDDNQ-IVTSSGDMTCALWDIETGQQCTAFTGHTGDVMSLSLSPDFR 197 Query: 289 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 +SG+ D++ K+WDIR KQ PGH ++ AV + P G +G D +L+ Sbjct: 198 TFISGACDASAKLWDIRDGMCKQTFPGHESDINAVAFFPSGNAFATGSDDATCRLF 253 Score = 59.3 bits (142), Expect = 7e-09 Identities = 41/143 (28%), Positives = 68/143 (47%), Gaps = 5/143 (3%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 + S D T LW+ +Q A TGH V + SPD + S + D S KLW+ G Sbjct: 159 TSSGDMTCALWDIETGQQCTA-FTGHTGDVMSLSLSPDFRTFISGACDASAKLWDIRDGM 217 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADE-----VY 191 F GH +D+ +++ +GS D+T +++DIRA Q+L ++ + + Sbjct: 218 CKQTFPGHESDINAVAFFPSGNAFATGSDDATCRLFDIRA---DQELAMYSHDNIICGIT 274 Query: 190 AVDWSPDGEKVVSGGKDRALKLW 122 +V +S G + +G D +W Sbjct: 275 SVAFSKSGRLLFAGYDDFNCNVW 297 Score = 58.5 bits (140), Expect = 1e-08 Identities = 41/141 (29%), Positives = 64/141 (45%), Gaps = 3/141 (2%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SG+ D + LW+ K GH+ +N V F P G A+ S D + +L++ I Sbjct: 201 SGACDASAKLWDIR-DGMCKQTFPGHESDINAVAFFPSGNAFATGSDDATCRLFD-IRAD 258 Query: 355 FVTAFRGH---VADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAV 185 A H + + +++S RLL +G D VWD ++ L GH + V + Sbjct: 259 QELAMYSHDNIICGITSVAFSKSGRLLFAGYDDFNCNVWDSMRQERAGVLAGHDNRVSCL 318 Query: 184 DWSPDGEKVVSGGKDRALKLW 122 + DG V +G D LK+W Sbjct: 319 GVTEDGMAVCTGSWDSFLKIW 339 Score = 52.4 bits (124), Expect = 8e-07 Identities = 25/73 (34%), Positives = 38/73 (52%) Frame = -2 Query: 340 RGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEK 161 RGH+A +Y + W++DSR L+S S+D L VWD +P + V ++P G Sbjct: 52 RGHLAKIYAMHWASDSRNLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSGSF 111 Query: 160 VVSGGKDRALKLW 122 V GG D ++ Sbjct: 112 VACGGLDNICSIY 124 Score = 42.4 bits (98), Expect = 8e-04 Identities = 28/128 (21%), Positives = 57/128 (44%), Gaps = 4/128 (3%) Frame = -2 Query: 493 ISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQ 314 I + + + GH + ++++ D + L SAS D + +W+ T V A + V Sbjct: 43 IQMRTRRTLRGHLAKIYAMHWASDSRNLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMT 102 Query: 313 ISWSADSRLLLSGSKDSTLKVWDIRAR----KLKQDLPGHADEVYAVDWSPDGEKVVSGG 146 +++ + G D+ ++ ++ R ++ ++LPGH + + D + V S G Sbjct: 103 CAYAPSGSFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIVTSSG 162 Query: 145 KDRALKLW 122 D LW Sbjct: 163 -DMTCALW 169 Score = 39.3 bits (90), Expect = 0.007 Identities = 27/100 (27%), Positives = 46/100 (46%), Gaps = 3/100 (3%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVV---NHVYFSPDGQWLASASFDKSVKLWNGI 365 +GSDD T L++ I + M H ++ V FS G+ L + D + +W+ + Sbjct: 243 TGSDDATCRLFD--IRADQELAMYSHDNIICGITSVAFSKSGRLLFAGYDDFNCNVWDSM 300 Query: 364 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD 245 + GH V + + D + +GS DS LK+W+ Sbjct: 301 RQERAGVLAGHDNRVSCLGVTEDGMAVCTGSWDSFLKIWN 340
>YH92_CAEEL (Q23256) Hypothetical WD-repeat protein ZC302.2| Length = 501 Score = 79.7 bits (195), Expect = 5e-15 Identities = 33/116 (28%), Positives = 66/116 (56%) Frame = -2 Query: 469 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 290 ++GH K V+ + FS G++L + S DK +K+WN + ++ H + SWS++S+ Sbjct: 209 ISGHTKSVSVIKFSYCGKYLGTGSADKQIKVWNTVDMTYLQTLASHQLGINDFSWSSNSQ 268 Query: 289 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 + S S D+T+K++D+ + + + GH + V+ ++P + S G D +++W Sbjct: 269 FIASASDDTTVKIFDVISGACLRTMRGHTNYVFCCSFNPQSSLIASAGFDETVRVW 324 Score = 78.6 bits (192), Expect = 1e-14 Identities = 39/138 (28%), Positives = 75/138 (54%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 +GS D + +W T+ + HQ +N +S + Q++ASAS D +VK+++ I+G Sbjct: 230 TGSADKQIKVWN-TVDMTYLQTLASHQLGINDFSWSSNSQFIASASDDTTVKIFDVISGA 288 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 + RGH V+ S++ S L+ S D T++VWD + + +P H+D + ++ ++ Sbjct: 289 CLRTMRGHTNYVFCCSFNPQSSLIASAGFDETVRVWDFKTGLCVKCIPAHSDPITSISYN 348 Query: 175 PDGEKVVSGGKDRALKLW 122 DG + + D +++W Sbjct: 349 HDGNTMATSSYDGCIRVW 366 Score = 70.1 bits (170), Expect = 4e-12 Identities = 45/140 (32%), Positives = 72/140 (51%), Gaps = 2/140 (1%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 S SDD T+ +++ IS M GH V F+P +ASA FD++V++W+ TG Sbjct: 272 SASDDTTVKIFD-VISGACLRTMRGHTNYVFCCSFNPQSSLIASAGFDETVRVWDFKTGL 330 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDL--PGHADEVYAVD 182 V H + IS++ D + + S D ++VWD + + L HA + V Sbjct: 331 CVKCIPAHSDPITSISYNHDGNTMATSSYDGCIRVWDAASGSCLKTLVDTDHAPVTF-VC 389 Query: 181 WSPDGEKVVSGGKDRALKLW 122 +SP+G+ ++S D +LKLW Sbjct: 390 FSPNGKYLLSAQLDSSLKLW 409 Score = 69.7 bits (169), Expect = 5e-12 Identities = 43/143 (30%), Positives = 69/143 (48%), Gaps = 5/143 (3%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 + S D + +W+ K + V V FSP+G++L SA D S+KLW+ K Sbjct: 356 TSSYDGCIRVWDAASGSCLKTLVDTDHAPVTFVCFSPNGKYLLSAQLDSSLKLWDPKKAK 415 Query: 355 FVTAFRGHVADVYQISWSADSRL---LLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAV 185 + + GH Y + + L ++SGS+D + VW I+ +++ Q L GH V A Sbjct: 416 PLKYYNGHKNKKYCLFANMSVPLGKHIISGSEDGRILVWSIQTKQIVQILEGHTTPVLAT 475 Query: 184 DWSPDGEKVVSGG--KDRALKLW 122 D P + SGG D +++W Sbjct: 476 DSHPTLNIIASGGLEPDNVIRIW 498 Score = 39.3 bits (90), Expect = 0.007 Identities = 28/99 (28%), Positives = 43/99 (43%), Gaps = 9/99 (9%) Frame = -2 Query: 373 NGITGK-------FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDL 215 +GIT K V GH V I +S + L +GS D +KVW+ Q L Sbjct: 192 SGITKKPENGEFSLVKTISGHTKSVSVIKFSYCGKYLGTGSADKQIKVWNTVDMTYLQTL 251 Query: 214 PGHADEVYAVDWSPDGEKVVSGGKDRALKLW--MN*ACL 104 H + WS + + + S D +K++ ++ ACL Sbjct: 252 ASHQLGINDFSWSSNSQFIASASDDTTVKIFDVISGACL 290
>TAF73_SCHPO (O74319) Transcription initiation factor TFIID subunit taf73| (Transcription initiation factor TFIID 73 kDa subunit) (TAFII-73) Length = 642 Score = 79.3 bits (194), Expect = 6e-15 Identities = 45/138 (32%), Positives = 69/138 (50%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 + S D T LW+ + P GHQ V+ V F P+ +LA+ S D + ++W+ TG Sbjct: 462 TASHDQTARLWDVEHAA-PLRVFVGHQNDVDCVSFHPNAAYLATGSSDHTTRMWDVRTGG 520 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 V F H + V + SAD L S + +KVWD+R+ H+ VY++ +S Sbjct: 521 TVRVFNAHHSPVSALCMSADGLSLASADESGIIKVWDLRSSNQHVSFVKHSSIVYSLSFS 580 Query: 175 PDGEKVVSGGKDRALKLW 122 D + +VSGG D + W Sbjct: 581 YDNKILVSGGADTDVNFW 598 Score = 70.1 bits (170), Expect = 4e-12 Identities = 42/138 (30%), Positives = 67/138 (48%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 S S+D LW +K + GH + V FSP G + A+AS D++ +LW+ Sbjct: 420 SCSEDGFTRLWSKD-TKSTIVKYAGHNAPIWDVQFSPFGYYFATASHDQTARLWDVEHAA 478 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 + F GH DV +S+ ++ L +GS D T ++WD+R + H V A+ S Sbjct: 479 PLRVFVGHQNDVDCVSFHPNAAYLATGSSDHTTRMWDVRTGGTVRVFNAHHSPVSALCMS 538 Query: 175 PDGEKVVSGGKDRALKLW 122 DG + S + +K+W Sbjct: 539 ADGLSLASADESGIIKVW 556 Score = 64.3 bits (155), Expect = 2e-10 Identities = 30/119 (25%), Positives = 57/119 (47%) Frame = -2 Query: 478 KARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSA 299 K+ + GH + V V SP +++ S S D +LW+ T + + GH A ++ + +S Sbjct: 396 KSSLIGHTRPVFGVSISPQKEFILSCSEDGFTRLWSKDTKSTIVKYAGHNAPIWDVQFSP 455 Query: 298 DSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 + S D T ++WD+ + GH ++V V + P+ + +G D ++W Sbjct: 456 FGYYFATASHDQTARLWDVEHAAPLRVFVGHQNDVDCVSFHPNAAYLATGSSDHTTRMW 514 Score = 53.9 bits (128), Expect = 3e-07 Identities = 31/106 (29%), Positives = 52/106 (49%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 +GS D T +W+ + H V+ + S DG LASA +K+W+ + Sbjct: 504 TGSSDHTTRMWDVRTGGTVRV-FNAHHSPVSALCMSADGLSLASADESGIIKVWDLRSSN 562 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQD 218 +F H + VY +S+S D+++L+SG D+ + WD+ R D Sbjct: 563 QHVSFVKHSSIVYSLSFSYDNKILVSGGADTDVNFWDLTYRNNLSD 608
>PRL1_ARATH (Q42384) PP1/PP2A phosphatases pleiotropic regulator PRL1| Length = 486 Score = 79.0 bits (193), Expect = 8e-15 Identities = 45/138 (32%), Positives = 72/138 (52%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 +GS D T+ +W+ K +TGH + V + S ++ SA DK VK W+ K Sbjct: 193 TGSADRTIKIWDVATGVL-KLTLTGHIEQVRGLAVSNRHTYMFSAGDDKQVKCWDLEQNK 251 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 + ++ GH++ VY ++ +LL+G +DS +VWDIR + L GH + V +V Sbjct: 252 VIRSYHGHLSGVYCLALHPTLDVLLTGGRDSVCRVWDIRTKMQIFALSGHDNTVCSVFTR 311 Query: 175 PDGEKVVSGGKDRALKLW 122 P +VV+G D +K W Sbjct: 312 PTDPQVVTGSHDTTIKFW 329 Score = 72.0 bits (175), Expect = 1e-12 Identities = 32/114 (28%), Positives = 55/114 (48%) Frame = -2 Query: 463 GHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLL 284 GH V V F P +W + S D+++K+W+ TG GH+ V ++ S + Sbjct: 174 GHLGWVRSVAFDPSNEWFCTGSADRTIKIWDVATGVLKLTLTGHIEQVRGLAVSNRHTYM 233 Query: 283 LSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 S D +K WD+ K+ + GH VY + P + +++GG+D ++W Sbjct: 234 FSAGDDKQVKCWDLEQNKVIRSYHGHLSGVYCLALHPTLDVLLTGGRDSVCRVW 287 Score = 47.8 bits (112), Expect = 2e-05 Identities = 22/73 (30%), Positives = 38/73 (52%) Frame = -2 Query: 340 RGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEK 161 +GH+ V +++ + +GS D T+K+WD+ LK L GH ++V + S Sbjct: 173 QGHLGWVRSVAFDPSNEWFCTGSADRTIKIWDVATGVLKLTLTGHIEQVRGLAVSNRHTY 232 Query: 160 VVSGGKDRALKLW 122 + S G D+ +K W Sbjct: 233 MFSAGDDKQVKCW 245 Score = 37.7 bits (86), Expect = 0.020 Identities = 32/146 (21%), Positives = 63/146 (43%), Gaps = 8/146 (5%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 +GS D T+ W+ K + +T H+K V + P ASAS D + K ++ G+ Sbjct: 319 TGSHDTTIKFWDLRYGKT-MSTLTHHKKSVRAMTLHPKENAFASASADNTKK-FSLPKGE 376 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDL-----PGHADE-- 197 F + + ++++G + ++ WD ++ Q PG + Sbjct: 377 FCHNMLSQQKTIINAMAVNEDGVMVTGGDNGSIWFWDWKSGHSFQQSETIVQPGSLESEA 436 Query: 196 -VYAVDWSPDGEKVVSGGKDRALKLW 122 +YA + G ++V+ D+ +K+W Sbjct: 437 GIYAACYDNTGSRLVTCEADKTIKMW 462
>PLRG1_RAT (Q9WUC8) Pleiotropic regulator 1| Length = 514 Score = 78.2 bits (191), Expect = 1e-14 Identities = 42/138 (30%), Positives = 69/138 (50%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 +GS D T+ +W+ K K +TGH V V S +L S DK VK W+ K Sbjct: 221 TGSADRTIKIWDLASGKL-KLSLTGHISTVRGVIVSTRSPYLFSCGEDKQVKCWDLEYNK 279 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 + + GH++ VY + +L++ S+DST ++WD+R + L GH + V V Sbjct: 280 VIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQ 339 Query: 175 PDGEKVVSGGKDRALKLW 122 ++++G D ++LW Sbjct: 340 AAEPQIITGSHDTTIRLW 357 Score = 71.6 bits (174), Expect = 1e-12 Identities = 33/116 (28%), Positives = 59/116 (50%) Frame = -2 Query: 469 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 290 ++GH V + P QW + S D+++K+W+ +GK + GH++ V + S S Sbjct: 200 ISGHLGWVRCIAVEPGNQWFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRSP 259 Query: 289 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 L S +D +K WD+ K+ + GH VY +D P + +V+ +D ++W Sbjct: 260 YLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIW 315 Score = 49.3 bits (116), Expect = 7e-06 Identities = 26/79 (32%), Positives = 40/79 (50%) Frame = -2 Query: 358 KFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDW 179 K GH+ V I+ ++ ++GS D T+K+WD+ + KLK L GH V V Sbjct: 195 KLYRVISGHLGWVRCIAVEPGNQWFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIV 254 Query: 178 SPDGEKVVSGGKDRALKLW 122 S + S G+D+ +K W Sbjct: 255 STRSPYLFSCGEDKQVKCW 273 Score = 41.6 bits (96), Expect = 0.001 Identities = 34/136 (25%), Positives = 56/136 (41%) Frame = -2 Query: 529 SDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFV 350 S D T +W+ +K ++GH V V + + S D +++LW+ + GK Sbjct: 307 SRDSTARIWDVR-TKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVAGKTR 365 Query: 349 TAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPD 170 H V + SGS D+ +K W Q+L GH + + + D Sbjct: 366 VTLTNHKKSVRAVVLHPLHYTFASGSPDN-IKQWKFPDGGFIQNLSGHNAIINTLAVNTD 424 Query: 169 GEKVVSGGKDRALKLW 122 G +VSG + + LW Sbjct: 425 G-VLVSGADNGTMHLW 439
>PLRG1_HUMAN (O43660) Pleiotropic regulator 1| Length = 514 Score = 78.2 bits (191), Expect = 1e-14 Identities = 42/138 (30%), Positives = 69/138 (50%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 +GS D T+ +W+ K K +TGH V V S +L S DK VK W+ K Sbjct: 221 TGSADRTIKIWDLASGKL-KLSLTGHISTVRGVIVSTRSPYLFSCGEDKQVKCWDLEYNK 279 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 + + GH++ VY + +L++ S+DST ++WD+R + L GH + V V Sbjct: 280 VIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQ 339 Query: 175 PDGEKVVSGGKDRALKLW 122 ++++G D ++LW Sbjct: 340 AAEPQIITGSHDTTIRLW 357 Score = 71.6 bits (174), Expect = 1e-12 Identities = 33/116 (28%), Positives = 59/116 (50%) Frame = -2 Query: 469 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 290 ++GH V + P QW + S D+++K+W+ +GK + GH++ V + S S Sbjct: 200 ISGHLGWVRCIAVEPGNQWFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRSP 259 Query: 289 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 L S +D +K WD+ K+ + GH VY +D P + +V+ +D ++W Sbjct: 260 YLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIW 315 Score = 49.3 bits (116), Expect = 7e-06 Identities = 26/79 (32%), Positives = 40/79 (50%) Frame = -2 Query: 358 KFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDW 179 K GH+ V I+ ++ ++GS D T+K+WD+ + KLK L GH V V Sbjct: 195 KLYRVISGHLGWVRCIAVEPGNQWFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIV 254 Query: 178 SPDGEKVVSGGKDRALKLW 122 S + S G+D+ +K W Sbjct: 255 STRSPYLFSCGEDKQVKCW 273 Score = 43.5 bits (101), Expect = 4e-04 Identities = 34/136 (25%), Positives = 56/136 (41%) Frame = -2 Query: 529 SDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFV 350 S D T +W+ +K ++GH V V + + S D +++LW+ + GK Sbjct: 307 SRDSTARIWDVR-TKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVAGKTR 365 Query: 349 TAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPD 170 H V + SGS D+ +K W Q+L GH + + + D Sbjct: 366 VTLTNHKKSVRAVVLHPRHYTFASGSPDN-IKQWKFPDGSFIQNLSGHNAIINTLTVNSD 424 Query: 169 GEKVVSGGKDRALKLW 122 G +VSG + + LW Sbjct: 425 G-VLVSGADNGTMHLW 439
>PLRG1_MOUSE (Q922V4) Pleiotropic regulator 1| Length = 513 Score = 78.2 bits (191), Expect = 1e-14 Identities = 42/138 (30%), Positives = 69/138 (50%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 +GS D T+ +W+ K K +TGH V V S +L S DK VK W+ K Sbjct: 220 TGSADRTIKIWDLASGKL-KLSLTGHISTVRGVIVSTRSPYLFSCGEDKQVKCWDLEYNK 278 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 + + GH++ VY + +L++ S+DST ++WD+R + L GH + V V Sbjct: 279 VIRHYHGHLSAVYGLDLHPTLDVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQ 338 Query: 175 PDGEKVVSGGKDRALKLW 122 ++++G D ++LW Sbjct: 339 AAEPQIITGSHDTTIRLW 356 Score = 71.6 bits (174), Expect = 1e-12 Identities = 33/116 (28%), Positives = 59/116 (50%) Frame = -2 Query: 469 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 290 ++GH V + P QW + S D+++K+W+ +GK + GH++ V + S S Sbjct: 199 ISGHLGWVRCIAVEPGNQWFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRSP 258 Query: 289 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 L S +D +K WD+ K+ + GH VY +D P + +V+ +D ++W Sbjct: 259 YLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTLDVLVTCSRDSTARIW 314 Score = 49.3 bits (116), Expect = 7e-06 Identities = 26/79 (32%), Positives = 40/79 (50%) Frame = -2 Query: 358 KFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDW 179 K GH+ V I+ ++ ++GS D T+K+WD+ + KLK L GH V V Sbjct: 194 KLYRVISGHLGWVRCIAVEPGNQWFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIV 253 Query: 178 SPDGEKVVSGGKDRALKLW 122 S + S G+D+ +K W Sbjct: 254 STRSPYLFSCGEDKQVKCW 272 Score = 41.2 bits (95), Expect = 0.002 Identities = 34/136 (25%), Positives = 56/136 (41%) Frame = -2 Query: 529 SDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFV 350 S D T +W+ +K ++GH V V + + S D +++LW+ + GK Sbjct: 306 SRDSTARIWDVR-TKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVAGKTR 364 Query: 349 TAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPD 170 H V + SGS D+ +K W Q+L GH + + + D Sbjct: 365 VTLTNHKKSVRAVVLHPLLYTFASGSPDN-IKQWKFPDGGFIQNLSGHNAIINTLAVNAD 423 Query: 169 GEKVVSGGKDRALKLW 122 G +VSG + + LW Sbjct: 424 G-VLVSGADNGTMHLW 438
>TBL1Y_HUMAN (Q9BQ87) F-box-like/WD-repeat protein TBL1Y (Transducin beta-like| 1Y protein) (Transducin-beta-like 1, Y-linked) Length = 522 Score = 78.2 bits (191), Expect = 1e-14 Identities = 42/129 (32%), Positives = 64/129 (49%), Gaps = 9/129 (6%) Frame = -2 Query: 481 PKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWS 302 P GH VN + + P G LAS S D ++K+W+ V + H ++Y I WS Sbjct: 351 PVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQDACVHDLQAHSKEIYTIKWS 410 Query: 301 A---------DSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSG 149 S +L S S DST+++WD+ L H + VY+V +SPDG+ + SG Sbjct: 411 PTGPATSNPNSSIMLASASFDSTVRLWDVEQGVCTHTLMKHQEPVYSVAFSPDGKYLASG 470 Query: 148 GKDRALKLW 122 D+ + +W Sbjct: 471 SFDKYVHIW 479 Score = 63.5 bits (153), Expect = 3e-10 Identities = 43/143 (30%), Positives = 66/143 (46%), Gaps = 11/143 (7%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKA--RMTGHQKVVNHVYFSPDGQ---------WLASASFDK 389 S SDD T+ +W KQ + H K + + +SP G LASASFD Sbjct: 376 SCSDDMTLKIWS---MKQDACVHDLQAHSKEIYTIKWSPTGPATSNPNSSIMLASASFDS 432 Query: 388 SVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPG 209 +V+LW+ G H VY +++S D + L SGS D + +W+ ++ L G Sbjct: 433 TVRLWDVEQGVCTHTLMKHQEPVYSVAFSPDGKYLASGSFDKYVHIWNTQSGSLVHSYQG 492 Query: 208 HADEVYAVDWSPDGEKVVSGGKD 140 ++ V W+ G+KV + D Sbjct: 493 -TGGIFEVCWNARGDKVGASASD 514 Score = 59.3 bits (142), Expect = 7e-09 Identities = 34/98 (34%), Positives = 55/98 (56%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 S S D T+ LW+ M HQ+ V V FSPDG++LAS SFDK V +WN +G Sbjct: 427 SASFDSTVRLWDVEQGVCTHTLMK-HQEPVYSVAFSPDGKYLASGSFDKYVHIWNTQSGS 485 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDI 242 V +++G ++++ W+A + + + D ++ V D+ Sbjct: 486 LVHSYQG-TGGIFEVCWNARGDKVGASASDGSVCVLDL 522 Score = 54.3 bits (129), Expect = 2e-07 Identities = 43/192 (22%), Positives = 64/192 (33%), Gaps = 54/192 (28%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKA---------RMTGHQ----KVVNHVYFSPDGQWLASASF 395 SGS D T +W + + R GH K V + ++ DG LA S+ Sbjct: 196 SGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPSNKDVTSLDWNSDGTLLAMGSY 255 Query: 394 DKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDL 215 D ++W G + H ++ + W+ +LS D T +WD + KQ Sbjct: 256 DGFARIWTE-NGNLASTLGQHKGPIFALKWNKKGNYVLSAGVDKTTIIWDAHTGEAKQQF 314 Query: 214 P-----------------------------------------GHADEVYAVDWSPDGEKV 158 P GH +EV A+ W P G + Sbjct: 315 PFHSAPALDVDWQNNMTFASCSTDMCIHVCRLGCDHPVKTFQGHTNEVNAIKWDPSGMLL 374 Query: 157 VSGGKDRALKLW 122 S D LK+W Sbjct: 375 ASCSDDMTLKIW 386 Score = 53.1 bits (126), Expect = 5e-07 Identities = 36/130 (27%), Positives = 57/130 (43%), Gaps = 14/130 (10%) Frame = -2 Query: 469 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLW------NGITGKFVTAF----RGHVA-- 326 + GH+ V ++P LAS S D + ++W NG + + V GH Sbjct: 175 LRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPS 234 Query: 325 --DVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVS 152 DV + W++D LL GS D ++W L L H ++A+ W+ G V+S Sbjct: 235 NKDVTSLDWNSDGTLLAMGSYDGFARIWTENG-NLASTLGQHKGPIFALKWNKKGNYVLS 293 Query: 151 GGKDRALKLW 122 G D+ +W Sbjct: 294 AGVDKTTIIW 303 Score = 51.6 bits (122), Expect = 1e-06 Identities = 28/91 (30%), Positives = 46/91 (50%), Gaps = 15/91 (16%) Frame = -2 Query: 349 TAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIR---------------ARKLKQDL 215 T RGH ++V+ +W+ S LL SGS DST ++W++ R+ D+ Sbjct: 173 TVLRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDV 232 Query: 214 PGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 P + D V ++DW+ DG + G D ++W Sbjct: 233 PSNKD-VTSLDWNSDGTLLAMGSYDGFARIW 262
>PRP46_DEBHA (Q6BU94) Pre-mRNA-splicing factor PRP46 (Pre-mRNA-processing| protein 46) Length = 417 Score = 78.2 bits (191), Expect = 1e-14 Identities = 43/143 (30%), Positives = 74/143 (51%), Gaps = 5/143 (3%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLW-----N 371 +GS D T+ +W+ S KA +TGH V + S +L S S DK+VK W N Sbjct: 139 TGSSDSTIKIWD-LASLNLKATITGHIMGVRSLAVSSRYPYLFSGSEDKTVKCWDLERTN 197 Query: 370 GITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVY 191 + G + + GHV +Y ++ + LL +G +DS ++VWD+R+R L GH ++ Sbjct: 198 SLLGCQIRNYHGHVGGIYAMALHPELDLLFTGGRDSVIRVWDLRSRTEIMVLSGHRSDIT 257 Query: 190 AVDWSPDGEKVVSGGKDRALKLW 122 ++ ++++ D ++LW Sbjct: 258 SIASQIGDPQIITSSMDATIRLW 280 Score = 60.1 bits (144), Expect = 4e-09 Identities = 33/119 (27%), Positives = 59/119 (49%), Gaps = 6/119 (5%) Frame = -2 Query: 460 HQKVVNHVYFSP-DGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLL 284 HQ V P +W + S D ++K+W+ + GH+ V ++ S+ L Sbjct: 120 HQGWVRSCTVDPVTNKWFVTGSSDSTIKIWDLASLNLKATITGHIMGVRSLAVSSRYPYL 179 Query: 283 LSGSKDSTLKVWDI-RARKLK----QDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 SGS+D T+K WD+ R L ++ GH +YA+ P+ + + +GG+D +++W Sbjct: 180 FSGSEDKTVKCWDLERTNSLLGCQIRNYHGHVGGIYAMALHPELDLLFTGGRDSVIRVW 238
>SEL10_CAEEL (Q93794) F-box/WD-repeat protein sel-10 (Suppressor/enhancer of| lin-12) (Sel-10 protein) Length = 587 Score = 78.2 bits (191), Expect = 1e-14 Identities = 47/139 (33%), Positives = 78/139 (56%), Gaps = 1/139 (0%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISK-QPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITG 359 +GSDD T+ +W I K + + GH V S G+++ S S D++VK+W+ + G Sbjct: 271 TGSDDNTLKVW--CIDKGEVMYTLVGHTGGVWTSQISQCGRYIVSGSTDRTVKVWSTVDG 328 Query: 358 KFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDW 179 + +GH + V ++ + +L++GS+D+TL+VWD+ + + L GH V V + Sbjct: 329 SLLHTLQGHTSTVRCMAMAGS--ILVTGSRDTTLRVWDVESGRHLATLHGHHAAVRCVQF 386 Query: 178 SPDGEKVVSGGKDRALKLW 122 DG VVSGG D +K+W Sbjct: 387 --DGTTVVSGGYDFTVKIW 403 Score = 64.7 bits (156), Expect = 2e-10 Identities = 41/141 (29%), Positives = 70/141 (49%), Gaps = 3/141 (2%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 +GS D T+ +W+ S + A + GH V V F DG + S +D +VK+WN TG+ Sbjct: 353 TGSRDTTLRVWDVE-SGRHLATLHGHHAAVRCVQF--DGTTVVSGGYDFTVKIWNAHTGR 409 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDI---RARKLKQDLPGHADEVYAV 185 + GH VY + + ++ ++ SGS D++++VWD ++ L GH + Sbjct: 410 CIRTLTGHNNRVYSLLFESERSIVCSGSLDTSIRVWDFTRPEGQECVALLQGHTSLTSGM 469 Query: 184 DWSPDGEKVVSGGKDRALKLW 122 G +VS D +++W Sbjct: 470 QLR--GNILVSCNADSHVRVW 488 Score = 52.4 bits (124), Expect = 8e-07 Identities = 33/91 (36%), Positives = 43/91 (47%) Frame = -2 Query: 394 DKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDL 215 DK K WN RGH V D +L++GS D+TLKVW I ++ L Sbjct: 234 DKIEKNWNANPIMGSAVLRGHEDHVITCMQIHDD-VLVTGSDDNTLKVWCIDKGEVMYTL 292 Query: 214 PGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 GH V+ S G +VSG DR +K+W Sbjct: 293 VGHTGGVWTSQISQCGRYIVSGSTDRTVKVW 323 Score = 52.0 bits (123), Expect = 1e-06 Identities = 30/97 (30%), Positives = 47/97 (48%) Frame = -2 Query: 412 LASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRAR 233 L + S D ++K+W G+ + GH V+ S R ++SGS D T+KVW Sbjct: 269 LVTGSDDNTLKVWCIDKGEVMYTLVGHTGGVWTSQISQCGRYIVSGSTDRTVKVWSTVDG 328 Query: 232 KLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 L L GH V + + G +V+G +D L++W Sbjct: 329 SLLHTLQGHTSTVRCMAMA--GSILVTGSRDTTLRVW 363
>TBLX_MOUSE (Q9QXE7) F-box-like/WD-repeat protein TBL1X (Transducin beta-like| 1X protein) Length = 527 Score = 77.8 bits (190), Expect = 2e-14 Identities = 41/130 (31%), Positives = 65/130 (50%), Gaps = 9/130 (6%) Frame = -2 Query: 484 QPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISW 305 +P GH VN + + P G LAS S D ++K+W+ V + H ++Y I W Sbjct: 353 RPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQDACVHDLQAHSKEIYTIKW 412 Query: 304 SA---------DSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVS 152 S + +L S S DST+++WD+ L H + VY+V +SPDG+ + S Sbjct: 413 SPTGPATSNPNSNIMLASASFDSTVRLWDVERGVCIHTLTKHQEPVYSVAFSPDGKYLAS 472 Query: 151 GGKDRALKLW 122 G D+ + +W Sbjct: 473 GSFDKCVHIW 482 Score = 64.7 bits (156), Expect = 2e-10 Identities = 43/143 (30%), Positives = 67/143 (46%), Gaps = 11/143 (7%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKA--RMTGHQKVVNHVYFSPDGQ---------WLASASFDK 389 S SDD T+ +W KQ + H K + + +SP G LASASFD Sbjct: 379 SCSDDMTLKIWS---MKQDACVHDLQAHSKEIYTIKWSPTGPATSNPNSNIMLASASFDS 435 Query: 388 SVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPG 209 +V+LW+ G + H VY +++S D + L SGS D + +W+ ++ L G Sbjct: 436 TVRLWDVERGVCIHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNTQSGSLVHSYRG 495 Query: 208 HADEVYAVDWSPDGEKVVSGGKD 140 ++ V W+ G+KV + D Sbjct: 496 -TGGIFEVCWNARGDKVGASASD 517 Score = 63.5 bits (153), Expect = 3e-10 Identities = 36/99 (36%), Positives = 57/99 (57%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 S S D T+ LW+ +T HQ+ V V FSPDG++LAS SFDK V +WN +G Sbjct: 430 SASFDSTVRLWDVERGVCIHT-LTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNTQSGS 488 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIR 239 V ++RG ++++ W+A + + + D ++ V D+R Sbjct: 489 LVHSYRG-TGGIFEVCWNARGDKVGASASDGSVCVLDLR 526 Score = 60.5 bits (145), Expect = 3e-09 Identities = 33/105 (31%), Positives = 47/105 (44%), Gaps = 9/105 (8%) Frame = -2 Query: 409 ASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARK 230 AS S D + + + V F+GH +V I W LL S S D TLK+W ++ Sbjct: 336 ASCSTDMCIHVCRLGCDRPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQDA 395 Query: 229 LKQDLPGHADEVYAVDWSPDGE---------KVVSGGKDRALKLW 122 DL H+ E+Y + WSP G + S D ++LW Sbjct: 396 CVHDLQAHSKEIYTIKWSPTGPATSNPNSNIMLASASFDSTVRLW 440 Score = 55.1 bits (131), Expect = 1e-07 Identities = 43/192 (22%), Positives = 65/192 (33%), Gaps = 54/192 (28%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKA---------RMTGHQ----KVVNHVYFSPDGQWLASASF 395 SGS D T +W + + R GH K V + ++ DG LA+ S+ Sbjct: 199 SGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPSNKDVTSLDWNSDGTLLATGSY 258 Query: 394 DKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDL 215 D ++W G + H ++ + W+ +LS D T +WD + KQ Sbjct: 259 DGFARIWTE-DGNLASTLGQHKGPIFALKWNKKGNYILSAGVDKTTIIWDAHTGEAKQQF 317 Query: 214 P-----------------------------------------GHADEVYAVDWSPDGEKV 158 P GH +EV A+ W P G + Sbjct: 318 PFHSAPALDVDWQNNTTFASCSTDMCIHVCRLGCDRPVKTFQGHTNEVNAIKWDPSGMLL 377 Query: 157 VSGGKDRALKLW 122 S D LK+W Sbjct: 378 ASCSDDMTLKIW 389 Score = 53.1 bits (126), Expect = 5e-07 Identities = 35/130 (26%), Positives = 58/130 (44%), Gaps = 14/130 (10%) Frame = -2 Query: 469 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLW------NGITGKFVTAF----RGHVA-- 326 + GH+ V ++P LAS S D + ++W NG + + V GH Sbjct: 178 LRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPS 237 Query: 325 --DVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVS 152 DV + W++D LL +GS D ++W L L H ++A+ W+ G ++S Sbjct: 238 NKDVTSLDWNSDGTLLATGSYDGFARIW-TEDGNLASTLGQHKGPIFALKWNKKGNYILS 296 Query: 151 GGKDRALKLW 122 G D+ +W Sbjct: 297 AGVDKTTIIW 306 Score = 52.4 bits (124), Expect = 8e-07 Identities = 28/91 (30%), Positives = 47/91 (51%), Gaps = 15/91 (16%) Frame = -2 Query: 349 TAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIR---------------ARKLKQDL 215 T RGH ++V+ +W+ S LL SGS DST ++W++ R+ D+ Sbjct: 176 TVLRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDV 235 Query: 214 PGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 P + D V ++DW+ DG + +G D ++W Sbjct: 236 PSNKD-VTSLDWNSDGTLLATGSYDGFARIW 265
>KTNB1_CHICK (Q5ZIU8) Katanin p80 WD40-containing subunit B1 (Katanin p80| subunit B1) (p80 katanin) Length = 657 Score = 77.8 bits (190), Expect = 2e-14 Identities = 46/132 (34%), Positives = 68/132 (51%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SGS D + LW+ K + H + V + FSPDG+WLASA+ D +VKLW+ GK Sbjct: 121 SGSLDTDIKLWDVR-RKGCIFKYKSHTQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGK 179 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 + F GH V + + LL SGS D T++ WD+ + + A V + ++ Sbjct: 180 VMFEFTGHSGPVNVVEFHPSEYLLASGSSDRTIRFWDLEKFHVVSCIEEEATPVRCILFN 239 Query: 175 PDGEKVVSGGKD 140 PDG + G +D Sbjct: 240 PDGCCLYGGFQD 251 Score = 76.3 bits (186), Expect = 5e-14 Identities = 39/138 (28%), Positives = 72/138 (52%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 +GS ++ +W+ +K + + GH+ + + F P G ++AS S D +KLW+ Sbjct: 79 AGSQSGSIRVWDLEAAKILRT-LLGHKANICSLDFHPYGSFVASGSLDTDIKLWDVRRKG 137 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 + ++ H V + +S D + L S + D T+K+WD+ A K+ + GH+ V V++ Sbjct: 138 CIFKYKSHTQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKVMFEFTGHSGPVNVVEFH 197 Query: 175 PDGEKVVSGGKDRALKLW 122 P + SG DR ++ W Sbjct: 198 PSEYLLASGSSDRTIRFW 215 Score = 71.2 bits (173), Expect = 2e-12 Identities = 35/138 (25%), Positives = 67/138 (48%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 +G DD + +W ++ Q + +TGH + + S + + + S S+++W+ K Sbjct: 38 TGGDDCQVNVW--SVKAQLRHELTGHTTPIESLQISAKEELIVAGSQSGSIRVWDLEAAK 95 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 + GH A++ + + + SGS D+ +K+WD+R + H V + +S Sbjct: 96 ILRTLLGHKANICSLDFHPYGSFVASGSLDTDIKLWDVRRKGCIFKYKSHTQAVRCLRFS 155 Query: 175 PDGEKVVSGGKDRALKLW 122 PDG+ + S D +KLW Sbjct: 156 PDGKWLASAADDHTVKLW 173 Score = 45.8 bits (107), Expect = 7e-05 Identities = 30/91 (32%), Positives = 42/91 (46%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 S +DD T+ LW+ T K TGH VN V F P LAS S D++++ W+ Sbjct: 163 SAADDHTVKLWDLTAGKV-MFEFTGHSGPVNVVEFHPSEYLLASGSSDRTIRFWDLEKFH 221 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDS 263 V+ V I ++ D L G +DS Sbjct: 222 VVSCIEEEATPVRCILFNPDGCCLYGGFQDS 252 Score = 40.0 bits (92), Expect = 0.004 Identities = 17/57 (29%), Positives = 34/57 (59%) Frame = -2 Query: 292 RLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 RLL +G D + VW ++A +L+ +L GH + ++ S E +V+G + ++++W Sbjct: 34 RLLATGGDDCQVNVWSVKA-QLRHELTGHTTPIESLQISAKEELIVAGSQSGSIRVW 89
>MET30_YEAST (P39014) F-box protein MET30 (Methionine requiring protein 30) (E3| ubiquitin ligase complex SCF(Met30) subunit MET30) Length = 640 Score = 77.4 bits (189), Expect = 2e-14 Identities = 45/138 (32%), Positives = 76/138 (55%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 +GS D T+ +W+ K + R++GH V +YF D + L + S DK++++WN ITG+ Sbjct: 317 TGSYDSTIGIWDLFTGKLIR-RLSGHSDGVKTLYF--DDRKLITGSLDKTIRVWNYITGE 373 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 ++ +RGH V +S + ++++SGS D T+KVW + +R L GH + V V Sbjct: 374 CISTYRGHSDSV--LSVDSYQKVIVSGSADKTVKVWHVESRTC-YTLRGHTEWVNCVKLH 430 Query: 175 PDGEKVVSGGKDRALKLW 122 P S D +++W Sbjct: 431 PKSFSCFSCSDDTTIRMW 448 Score = 58.9 bits (141), Expect = 9e-09 Identities = 31/97 (31%), Positives = 53/97 (54%) Frame = -2 Query: 412 LASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRAR 233 L + S+D ++ +W+ TGK + GH V + + D R L++GS D T++VW+ Sbjct: 315 LFTGSYDSTIGIWDLFTGKLIRRLSGHSDGVKTLYF--DDRKLITGSLDKTIRVWNYITG 372 Query: 232 KLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 + GH+D V +VD + +VSG D+ +K+W Sbjct: 373 ECISTYRGHSDSVLSVD--SYQKVIVSGSADKTVKVW 407 Score = 52.4 bits (124), Expect = 8e-07 Identities = 26/77 (33%), Positives = 47/77 (61%) Frame = -2 Query: 352 VTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSP 173 + F+GH+ V + ++ RLL +GS DST+ +WD+ KL + L GH+D V + + Sbjct: 295 IQEFKGHMDGVLTLQFNY--RLLFTGSYDSTIGIWDLFTGKLIRRLSGHSDGVKTLYF-- 350 Query: 172 DGEKVVSGGKDRALKLW 122 D K+++G D+ +++W Sbjct: 351 DDRKLITGSLDKTIRVW 367 Score = 52.0 bits (123), Expect = 1e-06 Identities = 43/185 (23%), Positives = 73/185 (39%), Gaps = 47/185 (25%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SGS D T+ +W + + + GH + VN V P S S D ++++W+ T Sbjct: 397 SGSADKTVKVWH--VESRTCYTLRGHTEWVNCVKLHPKSFSCFSCSDDTTIRMWDIRTNS 454 Query: 355 FVTAFRGHVADVYQI-------------------SWSADSRLLLSGSK------------ 269 + FRGHV V +I S D + G+ Sbjct: 455 CLKVFRGHVGQVQKIIPLTIKDVENLATDNTSDGSSPQDDPTMTDGADESDTPSNEQETV 514 Query: 268 ----------------DSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDR 137 D+T+K+WD++ K + GH + V+ D + D +++SG D Sbjct: 515 LDENIPYPTHLLSCGLDNTIKLWDVKTGKCIRTQFGHVEGVW--DIAADNFRIISGSHDG 572 Query: 136 ALKLW 122 ++K+W Sbjct: 573 SIKVW 577 Score = 51.6 bits (122), Expect = 1e-06 Identities = 26/68 (38%), Positives = 40/68 (58%) Frame = -2 Query: 412 LASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRAR 233 L S D ++KLW+ TGK + GHV V+ I +AD+ ++SGS D ++KVWD+++ Sbjct: 525 LLSCGLDNTIKLWDVKTGKCIRTQFGHVEGVWDI--AADNFRIISGSHDGSIKVWDLQSG 582 Query: 232 KLKQDLPG 209 K G Sbjct: 583 KCMHTFNG 590
>TBL1X_HUMAN (O60907) F-box-like/WD-repeat protein TBL1X (Transducin beta-like| 1X protein) (Transducin-beta-like 1, X-linked) (SMAP55) Length = 526 Score = 77.4 bits (189), Expect = 2e-14 Identities = 41/130 (31%), Positives = 65/130 (50%), Gaps = 9/130 (6%) Frame = -2 Query: 484 QPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISW 305 +P GH VN + + P G LAS S D ++K+W+ + + H ++Y I W Sbjct: 352 RPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQEVCIHDLQAHNKEIYTIKW 411 Query: 304 SA---------DSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVS 152 S + +L S S DST+++WDI L H + VY+V +SPDG+ + S Sbjct: 412 SPTGPATSNPNSNIMLASASFDSTVRLWDIERGVCTHTLTKHQEPVYSVAFSPDGKYLAS 471 Query: 151 GGKDRALKLW 122 G D+ + +W Sbjct: 472 GSFDKCVHIW 481 Score = 63.9 bits (154), Expect = 3e-10 Identities = 36/99 (36%), Positives = 57/99 (57%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 S S D T+ LW+ +T HQ+ V V FSPDG++LAS SFDK V +WN +G Sbjct: 429 SASFDSTVRLWDIERGVCTHT-LTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNTQSGN 487 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIR 239 V ++RG ++++ W+A + + + D ++ V D+R Sbjct: 488 LVHSYRG-TGGIFEVCWNARGDKVGASASDGSVCVLDLR 525 Score = 62.8 bits (151), Expect = 6e-10 Identities = 43/143 (30%), Positives = 66/143 (46%), Gaps = 11/143 (7%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKA--RMTGHQKVVNHVYFSPDGQ---------WLASASFDK 389 S SDD T+ +W KQ + H K + + +SP G LASASFD Sbjct: 378 SCSDDMTLKIWS---MKQEVCIHDLQAHNKEIYTIKWSPTGPATSNPNSNIMLASASFDS 434 Query: 388 SVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPG 209 +V+LW+ G H VY +++S D + L SGS D + +W+ ++ L G Sbjct: 435 TVRLWDIERGVCTHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNTQSGNLVHSYRG 494 Query: 208 HADEVYAVDWSPDGEKVVSGGKD 140 ++ V W+ G+KV + D Sbjct: 495 -TGGIFEVCWNARGDKVGASASD 516 Score = 59.3 bits (142), Expect = 7e-09 Identities = 33/105 (31%), Positives = 46/105 (43%), Gaps = 9/105 (8%) Frame = -2 Query: 409 ASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARK 230 AS S D + + + V F+GH +V I W LL S S D TLK+W ++ Sbjct: 335 ASCSTDMCIHVCRLGCDRPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQEV 394 Query: 229 LKQDLPGHADEVYAVDWSPDGE---------KVVSGGKDRALKLW 122 DL H E+Y + WSP G + S D ++LW Sbjct: 395 CIHDLQAHNKEIYTIKWSPTGPATSNPNSNIMLASASFDSTVRLW 439 Score = 53.1 bits (126), Expect = 5e-07 Identities = 42/192 (21%), Positives = 65/192 (33%), Gaps = 54/192 (28%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKA---------RMTGHQ----KVVNHVYFSPDGQWLASASF 395 SGS D T +W + + R GH K V + ++ +G LA+ S+ Sbjct: 198 SGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPSNKDVTSLDWNTNGTLLATGSY 257 Query: 394 DKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDL 215 D ++W G + H ++ + W+ +LS D T +WD + KQ Sbjct: 258 DGFARIWTE-DGNLASTLGQHKGPIFALKWNRKGNYILSAGVDKTTIIWDAHTGEAKQQF 316 Query: 214 P-----------------------------------------GHADEVYAVDWSPDGEKV 158 P GH +EV A+ W P G + Sbjct: 317 PFHSAPALDVDWQNNTTFASCSTDMCIHVCRLGCDRPVKTFQGHTNEVNAIKWDPSGMLL 376 Query: 157 VSGGKDRALKLW 122 S D LK+W Sbjct: 377 ASCSDDMTLKIW 388 Score = 50.4 bits (119), Expect = 3e-06 Identities = 34/130 (26%), Positives = 57/130 (43%), Gaps = 14/130 (10%) Frame = -2 Query: 469 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLW------NGITGKFVTAF----RGHVA-- 326 + GH+ V ++P LAS S D + ++W NG + + V GH Sbjct: 177 LRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPS 236 Query: 325 --DVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVS 152 DV + W+ + LL +GS D ++W L L H ++A+ W+ G ++S Sbjct: 237 NKDVTSLDWNTNGTLLATGSYDGFARIW-TEDGNLASTLGQHKGPIFALKWNRKGNYILS 295 Query: 151 GGKDRALKLW 122 G D+ +W Sbjct: 296 AGVDKTTIIW 305 Score = 50.4 bits (119), Expect = 3e-06 Identities = 27/91 (29%), Positives = 47/91 (51%), Gaps = 15/91 (16%) Frame = -2 Query: 349 TAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIR---------------ARKLKQDL 215 T RGH ++V+ +W+ S LL SGS DST ++W++ R+ D+ Sbjct: 175 TVLRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDV 234 Query: 214 PGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 P + D V ++DW+ +G + +G D ++W Sbjct: 235 PSNKD-VTSLDWNTNGTLLATGSYDGFARIW 264
>GBLP_LEIMA (Q25306) Guanine nucleotide-binding protein beta subunit-like| protein (Antigen LACK) Length = 312 Score = 77.4 bits (189), Expect = 2e-14 Identities = 50/142 (35%), Positives = 79/142 (55%), Gaps = 4/142 (2%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 + S D ++ +W+ + Q + + H K V V FSPD + + SA D +++WN + G+ Sbjct: 82 TASWDRSIRMWDLR-NGQCQRKFLKHTKDVLAVAFSPDDRLIVSAGRDNVIRVWN-VAGE 139 Query: 355 FVTAFR--GHVADVYQISWSA--DSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYA 188 + F GH V I +S + +++SGS D+T+KVW++ K ++ L GH++ V Sbjct: 140 CMHEFLRDGHEDWVSSICFSPSLEHPIVVSGSWDNTIKVWNVNGGKCERTLKGHSNYVST 199 Query: 187 VDWSPDGEKVVSGGKDRALKLW 122 V SPDG SGGKD A LW Sbjct: 200 VTVSPDGSLCASGGKDGAALLW 221 Score = 74.3 bits (181), Expect = 2e-13 Identities = 44/149 (29%), Positives = 77/149 (51%), Gaps = 11/149 (7%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQ--------PKARMTGHQKVVNHVYFSPDGQWLASASFDKSVK 380 S S D T+ W+ + P R+ GH V+ V + + +AS+D+S++ Sbjct: 31 STSRDGTVISWKANPDRHSVDSDYGLPNHRLEGHTGFVSCVSLAHATDYALTASWDRSIR 90 Query: 379 LWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDL-PGHA 203 +W+ G+ F H DV +++S D RL++S +D+ ++VW++ + + L GH Sbjct: 91 MWDLRNGQCQRKFLKHTKDVLAVAFSPDDRLIVSAGRDNVIRVWNVAGECMHEFLRDGHE 150 Query: 202 DEVYAVDWSPDGEK--VVSGGKDRALKLW 122 D V ++ +SP E VVSG D +K+W Sbjct: 151 DWVSSICFSPSLEHPIVVSGSWDNTIKVW 179 Score = 58.2 bits (139), Expect = 1e-08 Identities = 42/142 (29%), Positives = 72/142 (50%), Gaps = 4/142 (2%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SGS D T+ +W K + + GH V+ V SPDG AS D + LW+ TG+ Sbjct: 169 SGSWDNTIKVWNVNGGKCERT-LKGHSNYVSTVTVSPDGSLCASGGKDGAALLWDLSTGE 227 Query: 355 FVTAFRGHV-ADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLP---GHADEVYA 188 F+ +V + + QI +S +R + + + +L V+D+ ++ + +L E + Sbjct: 228 --QLFKINVESPINQIGFS-PNRFWMCVATERSLSVYDLESKAVIAELTPDGAKPSECIS 284 Query: 187 VDWSPDGEKVVSGGKDRALKLW 122 + WS DG + SG KD +++W Sbjct: 285 IAWSADGNTLYSGHKDNLIRVW 306 Score = 43.5 bits (101), Expect = 4e-04 Identities = 29/102 (28%), Positives = 51/102 (50%), Gaps = 4/102 (3%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SG D LW+ + +Q + +N + FSP+ W+ A+ ++S+ +++ + K Sbjct: 211 SGGKDGAALLWDLSTGEQ--LFKINVESPINQIGFSPNRFWMCVAT-ERSLSVYD-LESK 266 Query: 355 FV----TAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDI 242 V T ++ I+WSAD L SG KD+ ++VW I Sbjct: 267 AVIAELTPDGAKPSECISIAWSADGNTLYSGHKDNLIRVWSI 308
>GBLP_LEIIN (P62884) Guanine nucleotide-binding protein beta subunit-like| protein (Antigen LACK) (LiP36) (p36Li) Length = 312 Score = 77.4 bits (189), Expect = 2e-14 Identities = 50/142 (35%), Positives = 79/142 (55%), Gaps = 4/142 (2%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 + S D ++ +W+ + Q + + H K V V FSPD + + SA D +++WN + G+ Sbjct: 82 TASWDRSIRMWDLR-NGQCQRKFLKHTKDVLAVAFSPDDRLIVSAGRDNVIRVWN-VAGE 139 Query: 355 FVTAFR--GHVADVYQISWSA--DSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYA 188 + F GH V I +S + +++SGS D+T+KVW++ K ++ L GH++ V Sbjct: 140 CMHEFLRDGHEDWVSSICFSPSLEHPIVVSGSWDNTIKVWNVNGGKCERTLKGHSNYVST 199 Query: 187 VDWSPDGEKVVSGGKDRALKLW 122 V SPDG SGGKD A LW Sbjct: 200 VTVSPDGSLCASGGKDGAALLW 221 Score = 73.6 bits (179), Expect = 3e-13 Identities = 39/123 (31%), Positives = 69/123 (56%), Gaps = 3/123 (2%) Frame = -2 Query: 481 PKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWS 302 P R+ GH V+ V + + +AS+D+S+++W+ G+ F H DV +++S Sbjct: 57 PSHRLEGHTGFVSCVSLAHATDYALTASWDRSIRMWDLRNGQCQRKFLKHTKDVLAVAFS 116 Query: 301 ADSRLLLSGSKDSTLKVWDIRARKLKQDL-PGHADEVYAVDWSPDGEK--VVSGGKDRAL 131 D RL++S +D+ ++VW++ + + L GH D V ++ +SP E VVSG D + Sbjct: 117 PDDRLIVSAGRDNVIRVWNVAGECMHEFLRDGHEDWVSSICFSPSLEHPIVVSGSWDNTI 176 Query: 130 KLW 122 K+W Sbjct: 177 KVW 179 Score = 58.5 bits (140), Expect = 1e-08 Identities = 42/142 (29%), Positives = 73/142 (51%), Gaps = 4/142 (2%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SGS D T+ +W K + + GH V+ V SPDG AS D + LW+ TG+ Sbjct: 169 SGSWDNTIKVWNVNGGKCERT-LKGHSNYVSTVTVSPDGSLCASGGKDGAALLWDLSTGE 227 Query: 355 FVTAFRGHV-ADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLP---GHADEVYA 188 F+ +V + + QI++S +R + + + +L V+D+ ++ + +L E + Sbjct: 228 --QLFKINVESPINQIAFS-PNRFWMCVATERSLSVYDLESKAVIAELTPDGAKPSECIS 284 Query: 187 VDWSPDGEKVVSGGKDRALKLW 122 + WS DG + SG KD +++W Sbjct: 285 IAWSADGNTLYSGHKDNLIRVW 306 Score = 43.9 bits (102), Expect = 3e-04 Identities = 29/102 (28%), Positives = 51/102 (50%), Gaps = 4/102 (3%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SG D LW+ + +Q + +N + FSP+ W+ A+ ++S+ +++ + K Sbjct: 211 SGGKDGAALLWDLSTGEQ--LFKINVESPINQIAFSPNRFWMCVAT-ERSLSVYD-LESK 266 Query: 355 FV----TAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDI 242 V T ++ I+WSAD L SG KD+ ++VW I Sbjct: 267 AVIAELTPDGAKPSECISIAWSADGNTLYSGHKDNLIRVWSI 308
>GBLP_LEICH (P62883) Guanine nucleotide-binding protein beta subunit-like| protein (Antigen LACK) Length = 312 Score = 77.4 bits (189), Expect = 2e-14 Identities = 50/142 (35%), Positives = 79/142 (55%), Gaps = 4/142 (2%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 + S D ++ +W+ + Q + + H K V V FSPD + + SA D +++WN + G+ Sbjct: 82 TASWDRSIRMWDLR-NGQCQRKFLKHTKDVLAVAFSPDDRLIVSAGRDNVIRVWN-VAGE 139 Query: 355 FVTAFR--GHVADVYQISWSA--DSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYA 188 + F GH V I +S + +++SGS D+T+KVW++ K ++ L GH++ V Sbjct: 140 CMHEFLRDGHEDWVSSICFSPSLEHPIVVSGSWDNTIKVWNVNGGKCERTLKGHSNYVST 199 Query: 187 VDWSPDGEKVVSGGKDRALKLW 122 V SPDG SGGKD A LW Sbjct: 200 VTVSPDGSLCASGGKDGAALLW 221 Score = 73.6 bits (179), Expect = 3e-13 Identities = 39/123 (31%), Positives = 69/123 (56%), Gaps = 3/123 (2%) Frame = -2 Query: 481 PKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWS 302 P R+ GH V+ V + + +AS+D+S+++W+ G+ F H DV +++S Sbjct: 57 PSHRLEGHTGFVSCVSLAHATDYALTASWDRSIRMWDLRNGQCQRKFLKHTKDVLAVAFS 116 Query: 301 ADSRLLLSGSKDSTLKVWDIRARKLKQDL-PGHADEVYAVDWSPDGEK--VVSGGKDRAL 131 D RL++S +D+ ++VW++ + + L GH D V ++ +SP E VVSG D + Sbjct: 117 PDDRLIVSAGRDNVIRVWNVAGECMHEFLRDGHEDWVSSICFSPSLEHPIVVSGSWDNTI 176 Query: 130 KLW 122 K+W Sbjct: 177 KVW 179 Score = 58.5 bits (140), Expect = 1e-08 Identities = 42/142 (29%), Positives = 73/142 (51%), Gaps = 4/142 (2%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SGS D T+ +W K + + GH V+ V SPDG AS D + LW+ TG+ Sbjct: 169 SGSWDNTIKVWNVNGGKCERT-LKGHSNYVSTVTVSPDGSLCASGGKDGAALLWDLSTGE 227 Query: 355 FVTAFRGHV-ADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLP---GHADEVYA 188 F+ +V + + QI++S +R + + + +L V+D+ ++ + +L E + Sbjct: 228 --QLFKINVESPINQIAFS-PNRFWMCVATERSLSVYDLESKAVIAELTPDGAKPSECIS 284 Query: 187 VDWSPDGEKVVSGGKDRALKLW 122 + WS DG + SG KD +++W Sbjct: 285 IAWSADGNTLYSGHKDNLIRVW 306 Score = 43.9 bits (102), Expect = 3e-04 Identities = 29/102 (28%), Positives = 51/102 (50%), Gaps = 4/102 (3%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SG D LW+ + +Q + +N + FSP+ W+ A+ ++S+ +++ + K Sbjct: 211 SGGKDGAALLWDLSTGEQ--LFKINVESPINQIAFSPNRFWMCVAT-ERSLSVYD-LESK 266 Query: 355 FV----TAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDI 242 V T ++ I+WSAD L SG KD+ ++VW I Sbjct: 267 AVIAELTPDGAKPSECISIAWSADGNTLYSGHKDNLIRVWSI 308
>PRP46_CRYNE (Q5KDR4) Pre-mRNA-splicing factor PRP46 (Pre-mRNA-processing| protein 46) Length = 473 Score = 77.0 bits (188), Expect = 3e-14 Identities = 41/138 (29%), Positives = 71/138 (51%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 +G+ D + +W+ S + K +TGH + + S +L S + DK VK W+ T K Sbjct: 199 TGAGDRVIKIWD-LASGELKLSLTGHISTIRGLAVSDRHPYLFSCAEDKMVKCWDLETNK 257 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 + + GH + VY +S +L++G +D++++VWD+R R L GH V V Sbjct: 258 VIRHYHGHFSGVYSLSVHPTLDVLVTGGRDASVRVWDMRTRANIFTLTGHTSTVGDVKTQ 317 Query: 175 PDGEKVVSGGKDRALKLW 122 +++SG D ++LW Sbjct: 318 DSDPQIISGSMDSTVRLW 335 Score = 73.2 bits (178), Expect = 4e-13 Identities = 32/116 (27%), Positives = 64/116 (55%) Frame = -2 Query: 469 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 290 ++GH V V P QW A+ + D+ +K+W+ +G+ + GH++ + ++ S Sbjct: 178 ISGHMGWVRAVAMDPGNQWFATGAGDRVIKIWDLASGELKLSLTGHISTIRGLAVSDRHP 237 Query: 289 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 L S ++D +K WD+ K+ + GH VY++ P + +V+GG+D ++++W Sbjct: 238 YLFSCAEDKMVKCWDLETNKVIRHYHGHFSGVYSLSVHPTLDVLVTGGRDASVRVW 293 Score = 43.1 bits (100), Expect = 5e-04 Identities = 41/189 (21%), Positives = 74/189 (39%), Gaps = 51/189 (26%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 +G D ++ +W+ ++ +TGH V V + S S D +V+LW+ GK Sbjct: 283 TGGRDASVRVWDMR-TRANIFTLTGHTSTVGDVKTQDSDPQIISGSMDSTVRLWDLAAGK 341 Query: 355 -------------------------------------------FVTAFRGHVADVYQISW 305 FV F GH A + +S Sbjct: 342 CMNTLTHHKKSVRALAIHPTEYSFASASSGGNNIKKWKCPEGIFVNNFVGHEAIINTLSI 401 Query: 304 SADSRLLLSGSKDSTLKVWDIRARKLKQDL-----PGHADE---VYAVDWSPDGEKVVSG 149 ++++ +L SG+ + TL +WD + Q L PG D V+ + G ++++G Sbjct: 402 NSEN-VLFSGADNGTLTLWDYKTGLPFQHLKDIPQPGSLDAEAGVFCSTFDKTGTRLITG 460 Query: 148 GKDRALKLW 122 G D+ +K++ Sbjct: 461 GADKTIKVY 469 Score = 40.8 bits (94), Expect = 0.002 Identities = 19/79 (24%), Positives = 37/79 (46%) Frame = -2 Query: 358 KFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDW 179 K GH+ V ++ ++ +G+ D +K+WD+ + +LK L GH + + Sbjct: 173 KLTRVISGHMGWVRAVAMDPGNQWFATGAGDRVIKIWDLASGELKLSLTGHISTIRGLAV 232 Query: 178 SPDGEKVVSGGKDRALKLW 122 S + S +D+ +K W Sbjct: 233 SDRHPYLFSCAEDKMVKCW 251
>PRP46_EMENI (Q5BE22) Pre-mRNA-splicing factor prp46 (Pre-mRNA-processing| protein 46) Length = 452 Score = 77.0 bits (188), Expect = 3e-14 Identities = 43/138 (31%), Positives = 67/138 (48%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SG+ D T+ +W + +TGH V + SP +L S DK VK W+ T K Sbjct: 160 SGAGDRTIKIWNLATGAL-RLTLTGHISTVRGLAVSPRHPYLFSCGEDKMVKCWDLETNK 218 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 + + GH++ VY ++ LL++G +D +VWD+R R L GH V V Sbjct: 219 VIRHYHGHLSGVYTLALHPRLDLLVTGGRDGVARVWDMRTRSNIHVLSGHTGTVADVQCQ 278 Query: 175 PDGEKVVSGGKDRALKLW 122 +V++G D ++LW Sbjct: 279 EADPQVITGSLDATVRLW 296 Score = 74.3 bits (181), Expect = 2e-13 Identities = 39/148 (26%), Positives = 70/148 (47%), Gaps = 10/148 (6%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKAR----------MTGHQKVVNHVYFSPDGQWLASASFDKS 386 +G D T + P+ ++Q ++GH V + P+ +W AS + D++ Sbjct: 107 AGDDKPTSLIQRPSATRQQPPEWHAPWKLMRVISGHLGWVRSLAVEPNNEWFASGAGDRT 166 Query: 385 VKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGH 206 +K+WN TG GH++ V ++ S L S +D +K WD+ K+ + GH Sbjct: 167 IKIWNLATGALRLTLTGHISTVRGLAVSPRHPYLFSCGEDKMVKCWDLETNKVIRHYHGH 226 Query: 205 ADEVYAVDWSPDGEKVVSGGKDRALKLW 122 VY + P + +V+GG+D ++W Sbjct: 227 LSGVYTLALHPRLDLLVTGGRDGVARVW 254 Score = 50.1 bits (118), Expect = 4e-06 Identities = 39/146 (26%), Positives = 69/146 (47%), Gaps = 8/146 (5%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 +GS D T+ LW+ K +T H+K + + P ASAS S+K W G+ Sbjct: 286 TGSLDATVRLWDLAAGKTMGV-LTHHKKGIRSLATHPREFTFASASTG-SIKQWKCPGGE 343 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDL-----PGHADE-- 197 F+ F GH A + +S + D+ +L SG + ++ WD + Q + PG + Sbjct: 344 FMQNFEGHNAIINTLSVNEDN-VLFSGGDNGSMSFWDWKTGYRYQTIDTTAQPGSLEAEA 402 Query: 196 -VYAVDWSPDGEKVVSGGKDRALKLW 122 + + G ++++G D+ +K+W Sbjct: 403 GIMTSTFDRTGLRLITGEADKTIKVW 428 Score = 34.7 bits (78), Expect = 0.17 Identities = 25/116 (21%), Positives = 46/116 (39%) Frame = -2 Query: 469 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 290 ++GH V V + + S D +V+LW+ GK + H + ++ Sbjct: 265 LSGHTGTVADVQCQEADPQVITGSLDATVRLWDLAAGKTMGVLTHHKKGIRSLATHPREF 324 Query: 289 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 S S S +K W + Q+ GH + + + D + SGG + ++ W Sbjct: 325 TFASASTGS-IKQWKCPGGEFMQNFEGHNAIINTLSVNED-NVLFSGGDNGSMSFW 378
>TRCB_XENLA (Q91854) Beta-TrCP (Beta-transducin repeat-containing protein)| Length = 518 Score = 76.6 bits (187), Expect = 4e-14 Identities = 44/138 (31%), Positives = 77/138 (55%), Gaps = 2/138 (1%) Frame = -2 Query: 529 SDDFTMFLWEPTISKQPKAR--MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 S D ++ +W+ + R + GH+ VN V F D +++ SAS D+++K+WN T + Sbjct: 329 SKDRSIAVWDMASATDITLRRVLVGHRAAVNVVDF--DDKYIVSASGDRTIKVWNTSTCE 386 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 FV GH + + + RL++SGS D+T+++WDI + L GH + V + + Sbjct: 387 FVRTLNGHKRGIACLQYR--DRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRF- 443 Query: 175 PDGEKVVSGGKDRALKLW 122 D +++VSG D +K+W Sbjct: 444 -DNKRIVSGAYDGKIKVW 460 Score = 53.9 bits (128), Expect = 3e-07 Identities = 39/146 (26%), Positives = 75/146 (51%), Gaps = 3/146 (2%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SG D T+ +W+ + + K + GH V + + D + + + S D +V++W+ TG+ Sbjct: 247 SGLRDNTIKIWDKN-TLECKRVLMGHTGSVLCLQY--DERVIITGSSDSTVRVWDVNTGE 303 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRAR---KLKQDLPGHADEVYAV 185 + H V + ++ + ++++ SKD ++ VWD+ + L++ L GH V V Sbjct: 304 MLNTLIHHCEAVLHLRFN--NGMMVTCSKDRSIAVWDMASATDITLRRVLVGHRAAVNVV 361 Query: 184 DWSPDGEKVVSGGKDRALKLWMN*AC 107 D+ D + +VS DR +K+W C Sbjct: 362 DF--DDKYIVSASGDRTIKVWNTSTC 385 Score = 53.5 bits (127), Expect = 4e-07 Identities = 28/101 (27%), Positives = 54/101 (53%) Frame = -2 Query: 424 DGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD 245 D Q + S D ++K+W+ T + GH V + + D R++++GS DST++VWD Sbjct: 241 DDQKIVSGLRDNTIKIWDKNTLECKRVLMGHTGSVLCLQY--DERVIITGSSDSTVRVWD 298 Query: 244 IRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 + ++ L H + V + + + +V+ KDR++ +W Sbjct: 299 VNTGEMLNTLIHHCEAVLHLRF--NNGMMVTCSKDRSIAVW 337
>PRP46_CANAL (Q5A7Q3) Pre-mRNA-splicing factor PRP46 (Pre-mRNA-processing| protein 46) Length = 389 Score = 76.6 bits (187), Expect = 4e-14 Identities = 42/143 (29%), Positives = 74/143 (51%), Gaps = 5/143 (3%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLW-----N 371 +GS D T+ +W+ + KA +TGH + + S +L S DKS++ W N Sbjct: 103 TGSADSTIKIWDFE-NNSLKAVLTGHVLGIRSLCISKRHPYLFSGGEDKSLRCWDLERSN 161 Query: 370 GITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVY 191 G + ++ GH+ VY I + +L SG KD ++VWDIR+R L GH +++ Sbjct: 162 SDAGCQIRSYHGHLGGVYSIGLHPELDVLFSGGKDCVVRVWDIRSRVEAMTLLGHTNDIT 221 Query: 190 AVDWSPDGEKVVSGGKDRALKLW 122 +++ + +V++ D ++LW Sbjct: 222 SIETDYNDPQVITSSMDGTIRLW 244 Score = 56.2 bits (134), Expect = 6e-08 Identities = 27/104 (25%), Positives = 48/104 (46%), Gaps = 5/104 (4%) Frame = -2 Query: 418 QWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIR 239 +W + S D ++K+W+ GHV + + S L SG +D +L+ WD+ Sbjct: 99 KWYVTGSADSTIKIWDFENNSLKAVLTGHVLGIRSLCISKRHPYLFSGGEDKSLRCWDLE 158 Query: 238 ARKLK-----QDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 + GH VY++ P+ + + SGGKD +++W Sbjct: 159 RSNSDAGCQIRSYHGHLGGVYSIGLHPELDVLFSGGKDCVVRVW 202
>PRP46_YEAST (Q12417) Pre-mRNA-splicing factor PRP46 (Pre-mRNA-processing| protein 46) (Complexed with CEF1 protein 1) (PRP19-associated complex protein 50) (PRP nineteen-associated complex protein 50) Length = 451 Score = 76.3 bits (186), Expect = 5e-14 Identities = 44/138 (31%), Positives = 69/138 (50%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 +GS+D TM +W+ K K + GH V V S +L S S DK+VK W+ + Sbjct: 157 TGSNDTTMKVWDLATGKL-KTTLAGHVMTVRDVAVSDRHPYLFSVSEDKTVKCWDLEKNQ 215 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 + + GH++ V +S L+ + +DS +K+WD+R R L GH + V + Sbjct: 216 IIRDYYGHLSGVRTVSIHPTLDLIATAGRDSVIKLWDMRTRIPVITLVGHKGPINQVQCT 275 Query: 175 PDGEKVVSGGKDRALKLW 122 P +VVS D ++LW Sbjct: 276 PVDPQVVSSSTDATVRLW 293 Score = 73.9 bits (180), Expect = 3e-13 Identities = 39/117 (33%), Positives = 59/117 (50%), Gaps = 1/117 (0%) Frame = -2 Query: 469 MTGHQKVVNHVYFSP-DGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADS 293 + GH V V P D +W + S D ++K+W+ TGK T GHV V ++ S Sbjct: 135 INGHLGWVRCVAIDPVDNEWFITGSNDTTMKVWDLATGKLKTTLAGHVMTVRDVAVSDRH 194 Query: 292 RLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 L S S+D T+K WD+ ++ +D GH V V P + + + G+D +KLW Sbjct: 195 PYLFSVSEDKTVKCWDLEKNQIIRDYYGHLSGVRTVSIHPTLDLIATAGRDSVIKLW 251 Score = 49.3 bits (116), Expect = 7e-06 Identities = 39/133 (29%), Positives = 58/133 (43%), Gaps = 1/133 (0%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKAR-MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITG 359 S S+D T+ W+ + K R GH V V P +A+A D +KLW+ T Sbjct: 199 SVSEDKTVKCWD--LEKNQIIRDYYGHLSGVRTVSIHPTLDLIATAGRDSVIKLWDMRTR 256 Query: 358 KFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDW 179 V GH + Q+ + ++S S D+T+++WD+ A K + L H V A Sbjct: 257 IPVITLVGHKGPINQVQCTPVDPQVVSSSTDATVRLWDVVAGKTMKVLTHHKRSVRATAL 316 Query: 178 SPDGEKVVSGGKD 140 P V S D Sbjct: 317 HPKEFSVASACTD 329
>PF20_CHLRE (P93107) Flagellar WD-repeat protein PF20| Length = 606 Score = 76.3 bits (186), Expect = 5e-14 Identities = 47/139 (33%), Positives = 68/139 (48%), Gaps = 1/139 (0%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQP-KARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITG 359 SG D + +W+ KQ T H++ + V F G+ +AS S D +V+LW+ G Sbjct: 385 SGGGDSAVKIWD--FEKQRCVTTFTDHKQAIWSVRFHHLGEVVASGSLDHTVRLWDLPAG 442 Query: 358 KFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDW 179 K A RGHV V ++W S L + S D T+ VWD RA Q GH + V + Sbjct: 443 KCRMALRGHVDSVNDLAWQPFSSSLATASSDKTVSVWDARAGLCTQTYYGHQNSCNGVSF 502 Query: 178 SPDGEKVVSGGKDRALKLW 122 + G ++ S D +KLW Sbjct: 503 NILGTQLASTDADGVVKLW 521 Score = 74.7 bits (182), Expect = 2e-13 Identities = 42/142 (29%), Positives = 67/142 (47%), Gaps = 4/142 (2%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMT----GHQKVVNHVYFSPDGQWLASASFDKSVKLWNG 368 + SDD T +W P + GH+ V V F P G LAS D +VK+W+ Sbjct: 343 TASDDKTWKMWH-----MPGGDLIMCGEGHKDWVAGVDFHPAGTCLASGGGDSAVKIWDF 397 Query: 367 ITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYA 188 + VT F H ++ + + ++ SGS D T+++WD+ A K + L GH D V Sbjct: 398 EKQRCVTTFTDHKQAIWSVRFHHLGEVVASGSLDHTVRLWDLPAGKCRMALRGHVDSVND 457 Query: 187 VDWSPDGEKVVSGGKDRALKLW 122 + W P + + D+ + +W Sbjct: 458 LAWQPFSSSLATASSDKTVSVW 479 Score = 63.9 bits (154), Expect = 3e-10 Identities = 51/180 (28%), Positives = 72/180 (40%), Gaps = 42/180 (23%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SGS D T+ LW+ K A + GH VN + + P LA+AS DK+V +W+ G Sbjct: 427 SGSLDHTVRLWDLPAGKCRMA-LRGHVDSVNDLAWQPFSSSLATASSDKTVSVWDARAGL 485 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIR--------------ARK---- 230 + GH +S++ L S D +K+WD R A K Sbjct: 486 CTQTYYGHQNSCNGVSFNILGTQLASTDADGVVKLWDTRMTAEVATINTGKHPANKSCFD 545 Query: 229 ------------------------LKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 L+ +L GH D V AV + P G+ +VS G D +LW Sbjct: 546 RSGQVLAVACDDGKVKAYSTTDGVLQAELAGHEDAVQAVLFDPAGQYLVSCGSDNTFRLW 605 Score = 59.3 bits (142), Expect = 7e-09 Identities = 33/114 (28%), Positives = 52/114 (45%) Frame = -2 Query: 463 GHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLL 284 GH V ++ P L +AS DK+ K+W+ G + GH V + + L Sbjct: 324 GHLLSVANLALHPTKPILVTASDDKTWKMWHMPGGDLIMCGEGHKDWVAGVDFHPAGTCL 383 Query: 283 LSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 SG DS +K+WD ++ H +++V + GE V SG D ++LW Sbjct: 384 ASGGGDSAVKIWDFEKQRCVTTFTDHKQAIWSVRFHHLGEVVASGSLDHTVRLW 437 Score = 52.0 bits (123), Expect = 1e-06 Identities = 26/74 (35%), Positives = 39/74 (52%) Frame = -2 Query: 343 FRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGE 164 F+GH+ V ++ +L++ S D T K+W + L GH D V VD+ P G Sbjct: 322 FKGHLLSVANLALHPTKPILVTASDDKTWKMWHMPGGDLIMCGEGHKDWVAGVDFHPAGT 381 Query: 163 KVVSGGKDRALKLW 122 + SGG D A+K+W Sbjct: 382 CLASGGGDSAVKIW 395 Score = 35.8 bits (81), Expect = 0.078 Identities = 14/36 (38%), Positives = 21/36 (58%) Frame = -2 Query: 478 KARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWN 371 +A + GH+ V V F P GQ+L S D + +LW+ Sbjct: 571 QAELAGHEDAVQAVLFDPAGQYLVSCGSDNTFRLWS 606
>FBW1A_HUMAN (Q9Y297) F-box/WD-repeat protein 1A (F-box and WD-repeats protein| beta-TrCP) (E3RSIkappaB) (pIkappaBalpha-E3 receptor subunit) Length = 605 Score = 75.9 bits (185), Expect = 7e-14 Identities = 44/138 (31%), Positives = 76/138 (55%), Gaps = 2/138 (1%) Frame = -2 Query: 529 SDDFTMFLWEPTISKQPKAR--MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 S D ++ +W+ R + GH+ VN V F D +++ SAS D+++K+WN T + Sbjct: 400 SKDRSIAVWDMASPTDITLRRVLVGHRAAVNVVDF--DDKYIVSASGDRTIKVWNTSTCE 457 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 FV GH + + + RL++SGS D+T+++WDI + L GH + V + + Sbjct: 458 FVRTLNGHKRGIACLQYR--DRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRF- 514 Query: 175 PDGEKVVSGGKDRALKLW 122 D +++VSG D +K+W Sbjct: 515 -DNKRIVSGAYDGKIKVW 531 Score = 55.8 bits (133), Expect = 7e-08 Identities = 40/146 (27%), Positives = 76/146 (52%), Gaps = 3/146 (2%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SG D T+ +W+ + + K +TGH V + + D + + + S D +V++W+ TG+ Sbjct: 318 SGLRDNTIKIWDKN-TLECKRILTGHTGSVLCLQY--DERVIITGSSDSTVRVWDVNTGE 374 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRAR---KLKQDLPGHADEVYAV 185 + H V + ++ + ++++ SKD ++ VWD+ + L++ L GH V V Sbjct: 375 MLNTLIHHCEAVLHLRFN--NGMMVTCSKDRSIAVWDMASPTDITLRRVLVGHRAAVNVV 432 Query: 184 DWSPDGEKVVSGGKDRALKLWMN*AC 107 D+ D + +VS DR +K+W C Sbjct: 433 DF--DDKYIVSASGDRTIKVWNTSTC 456 Score = 53.1 bits (126), Expect = 5e-07 Identities = 28/101 (27%), Positives = 54/101 (53%) Frame = -2 Query: 424 DGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD 245 D Q + S D ++K+W+ T + GH V + + D R++++GS DST++VWD Sbjct: 312 DDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSVLCLQY--DERVIITGSSDSTVRVWD 369 Query: 244 IRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 + ++ L H + V + + + +V+ KDR++ +W Sbjct: 370 VNTGEMLNTLIHHCEAVLHLRF--NNGMMVTCSKDRSIAVW 408
>GBB1_DROME (P26308) Guanine nucleotide-binding protein beta subunit 1| Length = 340 Score = 75.9 bits (185), Expect = 7e-14 Identities = 40/116 (34%), Positives = 64/116 (55%) Frame = -2 Query: 469 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 290 + GH ++ F D Q + ++S D S LW+ TG VT+F GH DV +S + + Sbjct: 139 LPGHGGYLSCCRFLDDNQ-IVTSSGDMSCGLWDIETGLQVTSFLGHTGDVMALSLAPQCK 197 Query: 289 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 +SG+ D++ K+WDIR KQ PGH ++ AV + P+G+ +G D +L+ Sbjct: 198 TFVSGACDASAKLWDIREGVCKQTFPGHESDINAVTFFPNGQAFATGSDDATCRLF 253 Score = 58.9 bits (141), Expect = 9e-09 Identities = 42/143 (29%), Positives = 68/143 (47%), Gaps = 5/143 (3%) Frame = -2 Query: 535 SGSDDFTMFLWE--PTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 362 SG+ D + LW+ + KQ GH+ +N V F P+GQ A+ S D + +L++ I Sbjct: 201 SGACDASAKLWDIREGVCKQT---FPGHESDINAVTFFPNGQAFATGSDDATCRLFD-IR 256 Query: 361 GKFVTAFRGH---VADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVY 191 A H + + +++S RLLL+G D VWD + L GH + V Sbjct: 257 ADQELAMYSHDNIICGITSVAFSKSGRLLLAGYDDFNCNVWDTMKAERSGILAGHDNRVS 316 Query: 190 AVDWSPDGEKVVSGGKDRALKLW 122 + + +G V +G D L++W Sbjct: 317 CLGVTENGMAVATGSWDSFLRVW 339 Score = 52.0 bits (123), Expect = 1e-06 Identities = 25/73 (34%), Positives = 36/73 (49%) Frame = -2 Query: 340 RGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEK 161 RGH+A +Y + W DSR L+S S+D L VWD +P + V ++P G Sbjct: 52 RGHLAKIYAMHWGNDSRNLVSASQDGKLIVWDSHTTNKVHAIPLRSSWVMTCAYAPSGSY 111 Query: 160 VVSGGKDRALKLW 122 V GG D ++ Sbjct: 112 VACGGLDNMCSIY 124 Score = 50.8 bits (120), Expect = 2e-06 Identities = 36/143 (25%), Positives = 69/143 (48%), Gaps = 5/143 (3%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 + S D + LW+ Q + + GH V + +P + S + D S KLW+ G Sbjct: 159 TSSGDMSCGLWDIETGLQVTSFL-GHTGDVMALSLAPQCKTFVSGACDASAKLWDIREGV 217 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADE-----VY 191 F GH +D+ +++ + + +GS D+T +++DIRA Q+L ++ + + Sbjct: 218 CKQTFPGHESDINAVTFFPNGQAFATGSDDATCRLFDIRA---DQELAMYSHDNIICGIT 274 Query: 190 AVDWSPDGEKVVSGGKDRALKLW 122 +V +S G +++G D +W Sbjct: 275 SVAFSKSGRLLLAGYDDFNCNVW 297 Score = 40.8 bits (94), Expect = 0.002 Identities = 28/128 (21%), Positives = 58/128 (45%), Gaps = 4/128 (3%) Frame = -2 Query: 493 ISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQ 314 I + + + GH + +++ D + L SAS D + +W+ T V A + V Sbjct: 43 IQMRTRRTLRGHLAKIYAMHWGNDSRNLVSASQDGKLIVWDSHTTNKVHAIPLRSSWVMT 102 Query: 313 ISWSADSRLLLSGSKDSTLKVWDIRAR----KLKQDLPGHADEVYAVDWSPDGEKVVSGG 146 +++ + G D+ +++++ R ++ ++LPGH + + D + V S G Sbjct: 103 CAYAPSGSYVACGGLDNMCSIYNLKTREGNVRVSRELPGHGGYLSCCRFLDDNQIVTSSG 162 Query: 145 KDRALKLW 122 D + LW Sbjct: 163 -DMSCGLW 169 Score = 35.8 bits (81), Expect = 0.078 Identities = 26/100 (26%), Positives = 46/100 (46%), Gaps = 3/100 (3%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVV---NHVYFSPDGQWLASASFDKSVKLWNGI 365 +GSDD T L++ I + M H ++ V FS G+ L + D + +W+ + Sbjct: 243 TGSDDATCRLFD--IRADQELAMYSHDNIICGITSVAFSKSGRLLLAGYDDFNCNVWDTM 300 Query: 364 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD 245 + GH V + + + + +GS DS L+VW+ Sbjct: 301 KAERSGILAGHDNRVSCLGVTENGMAVATGSWDSFLRVWN 340
>GBB1_BRARE (Q6PH57) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 1 (Transducin beta chain 1) Length = 340 Score = 75.9 bits (185), Expect = 7e-14 Identities = 37/116 (31%), Positives = 64/116 (55%) Frame = -2 Query: 469 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 290 + GH ++ F D Q + ++S D + LW+ TG+ T F GH DV +S + D+R Sbjct: 139 LAGHTGYLSCCRFLDDNQ-IVTSSGDTTCALWDIETGQQTTTFAGHTGDVMSLSLAPDTR 197 Query: 289 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 L +SG+ D++ K+WD+R +Q GH ++ A+ + P+G +G D +L+ Sbjct: 198 LFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLF 253 Score = 59.3 bits (142), Expect = 7e-09 Identities = 39/140 (27%), Positives = 65/140 (46%), Gaps = 2/140 (1%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SG+ D + LW+ + TGH+ +N + F P+G A+ S D + +L++ + Sbjct: 201 SGACDASAKLWDVR-EGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQ 259 Query: 355 --FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 182 V + + + +++S RLLL+G D VWD L GH + V + Sbjct: 260 ELMVYSHDNIICGITSVAFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLG 319 Query: 181 WSPDGEKVVSGGKDRALKLW 122 + DG V +G D LK+W Sbjct: 320 VTDDGMAVATGSWDSFLKIW 339 Score = 55.5 bits (132), Expect = 9e-08 Identities = 38/143 (26%), Positives = 67/143 (46%), Gaps = 5/143 (3%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 + S D T LW+ +Q GH V + +PD + S + D S KLW+ G Sbjct: 159 TSSGDTTCALWDIETGQQTTT-FAGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGM 217 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADE-----VY 191 F GH +D+ I + + +GS D+T +++D+RA Q+L ++ + + Sbjct: 218 CRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRA---DQELMVYSHDNIICGIT 274 Query: 190 AVDWSPDGEKVVSGGKDRALKLW 122 +V +S G +++G D +W Sbjct: 275 SVAFSKSGRLLLAGYDDFNCNVW 297 Score = 54.3 bits (129), Expect = 2e-07 Identities = 25/73 (34%), Positives = 37/73 (50%) Frame = -2 Query: 340 RGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEK 161 RGH+A +Y + W DSRLL+S S+D L +WD +P + V ++P G Sbjct: 52 RGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNY 111 Query: 160 VVSGGKDRALKLW 122 V GG D ++ Sbjct: 112 VACGGLDNICSIY 124 Score = 40.8 bits (94), Expect = 0.002 Identities = 33/169 (19%), Positives = 59/169 (34%), Gaps = 45/169 (26%) Frame = -2 Query: 493 ISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAF--------- 341 I + + + GH + +++ D + L SAS D + +W+ T V A Sbjct: 43 IQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMT 102 Query: 340 --------------RGHVADVYQISWS----------------------ADSRLLLSGSK 269 ++ +Y + D +++ S Sbjct: 103 CAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSG 162 Query: 268 DSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 D+T +WDI + GH +V ++ +PD VSG D + KLW Sbjct: 163 DTTCALWDIETGQQTTTFAGHTGDVMSLSLAPDTRLFVSGACDASAKLW 211 Score = 37.4 bits (85), Expect = 0.027 Identities = 25/100 (25%), Positives = 45/100 (45%), Gaps = 3/100 (3%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVV---NHVYFSPDGQWLASASFDKSVKLWNGI 365 +GSDD T L++ + + + H ++ V FS G+ L + D + +W+ + Sbjct: 243 TGSDDATCRLFD--LRADQELMVYSHDNIICGITSVAFSKSGRLLLAGYDDFNCNVWDAL 300 Query: 364 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD 245 GH V + + D + +GS DS LK+W+ Sbjct: 301 KADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
>APAF_RAT (Q9EPV5) Apoptotic protease-activating factor 1 (Apaf-1)| Length = 1249 Score = 75.9 bits (185), Expect = 7e-14 Identities = 42/115 (36%), Positives = 61/115 (53%), Gaps = 2/115 (1%) Frame = -2 Query: 460 HQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR--L 287 H+ V FS D ++A+ S DK VK+W+ TGK V + H V ++ S L Sbjct: 656 HEDEVLCCAFSSDDSYIATCSVDKKVKIWDSGTGKLVHTYEEHSEQVNCCHFTNKSNHLL 715 Query: 286 LLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 L +GS DS LK+WD+ ++ + + GH + V +SPD E + S D LKLW Sbjct: 716 LATGSNDSFLKLWDLNQKECRNTMFGHTNSVTHCRFSPDDELLASCSADGTLKLW 770 Score = 70.5 bits (171), Expect = 3e-12 Identities = 40/114 (35%), Positives = 61/114 (53%) Frame = -2 Query: 463 GHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLL 284 GH+K V H+ F+ DG+ L S+S D +++WN T ++V + H V DSR L Sbjct: 1001 GHKKAVRHIQFTADGKTLISSSEDSVIQVWNWQTEEYV-FLQAHQETVKDFRLLRDSR-L 1058 Query: 283 LSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 LS S D T+KVW++ ++++D H V + S D K S D+ K+W Sbjct: 1059 LSWSFDGTVKVWNVITGRIERDFTCHQGTVLSCAISSDATKFSSTSADKTAKIW 1112 Score = 60.5 bits (145), Expect = 3e-09 Identities = 40/138 (28%), Positives = 62/138 (44%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 S S+D + +W + + HQ+ V D + L S SFD +VK+WN ITG+ Sbjct: 1020 SSSEDSVIQVWN--WQTEEYVFLQAHQETVKDFRLLRDSR-LLSWSFDGTVKVWNVITGR 1076 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 F H V + S+D+ S S D T K+W +L GH V +S Sbjct: 1077 IERDFTCHQGTVLSCAISSDATKFSSTSADKTAKIWSFELPSPLHELKGHNSCVRCSAFS 1136 Query: 175 PDGEKVVSGGKDRALKLW 122 DG + +G + +++W Sbjct: 1137 LDGILLATGDDNGEIRIW 1154 Score = 58.5 bits (140), Expect = 1e-08 Identities = 48/193 (24%), Positives = 77/193 (39%), Gaps = 55/193 (28%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITG- 359 +GS+D + LW+ K+ + M GH V H FSPD + LAS S D ++KLW+ + Sbjct: 718 TGSNDSFLKLWDLN-QKECRNTMFGHTNSVTHCRFSPDDELLASCSADGTLKLWDVRSAN 776 Query: 358 --------KFVTAFRGHVADVYQI----SWSADSRLLLSGSKDSTL-------------- 257 +F + DV I SWSAD ++ +K+ L Sbjct: 777 EKKSINVKRFFLSSEDPPEDVEVIVKCCSWSADGDRIIVAAKNKVLLLDIHTSGLLTEIH 836 Query: 256 ----------------------------KVWDIRARKLKQDLPGHADEVYAVDWSPDGEK 161 ++W+I +R D GH V+ V +SPDG Sbjct: 837 TGHHSTIQYCDFSPYDHLAVIALSQYCVELWNIDSRVKVADCRGHLSWVHGVMFSPDGSS 896 Query: 160 VVSGGKDRALKLW 122 ++ D+ +++W Sbjct: 897 FLTASDDQTIRVW 909 Score = 47.8 bits (112), Expect = 2e-05 Identities = 40/147 (27%), Positives = 67/147 (45%), Gaps = 9/147 (6%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 S S D T+ +W I+ + + T HQ V S D +S S DK+ K+W+ Sbjct: 1060 SWSFDGTVKVWN-VITGRIERDFTCHQGTVLSCAISSDATKFSSTSADKTAKIWSFELPS 1118 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKL---------KQDLPGHA 203 + +GH + V ++S D LL +G + +++W++ +L ++ H Sbjct: 1119 PLHELKGHNSCVRCSAFSLDGILLATGDDNGEIRIWNVSDGQLLHLCAPISIEEGTATHG 1178 Query: 202 DEVYAVDWSPDGEKVVSGGKDRALKLW 122 V V +SPD + +VS G LK W Sbjct: 1179 GWVTDVCFSPDRKMLVSAG--GYLKWW 1203 Score = 47.8 bits (112), Expect = 2e-05 Identities = 25/76 (32%), Positives = 38/76 (50%) Frame = -2 Query: 466 TGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRL 287 TGH + + FSP A V+LWN + V RGH++ V+ + +S D Sbjct: 837 TGHHSTIQYCDFSPYDHLAVIALSQYCVELWNIDSRVKVADCRGHLSWVHGVMFSPDGSS 896 Query: 286 LLSGSKDSTLKVWDIR 239 L+ S D T++VW+ R Sbjct: 897 FLTASDDQTIRVWETR 912 Score = 35.8 bits (81), Expect = 0.078 Identities = 25/103 (24%), Positives = 51/103 (49%) Frame = -2 Query: 430 SPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKV 251 SP +++A + ++K+ + ++ GH V I ++AD + L+S S+DS ++V Sbjct: 970 SPHLEYVAFGDEEGAIKIIELPNNRVFSSGIGHKKAVRHIQFTADGKTLISSSEDSVIQV 1029 Query: 250 WDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 W+ + + L H + V D +++S D +K+W Sbjct: 1030 WNWQTEEY-VFLQAHQETVKDFRLLRD-SRLLSWSFDGTVKVW 1070 Score = 28.9 bits (63), Expect = 9.5 Identities = 20/57 (35%), Positives = 28/57 (49%) Frame = -2 Query: 460 HQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 290 H V V FSPD + L SA +K WN +TG+ F + ++ +I S D R Sbjct: 1177 HGGWVTDVCFSPDRKMLVSAG--GYLKWWNVVTGESSQTFYTNGTNLKKIHVSPDFR 1231
>PEX7_HUMAN (O00628) Peroxisomal targeting signal 2 receptor (PTS2 receptor)| (Peroxin-7) Length = 323 Score = 75.9 bits (185), Expect = 7e-14 Identities = 45/140 (32%), Positives = 72/140 (51%), Gaps = 4/140 (2%) Frame = -2 Query: 529 SDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDG--QWLASASFDKSVKLWNGITGK 356 S D ++ LW+ + P H + V V +S Q + S S+D++VKLW+ GK Sbjct: 87 SGDGSLQLWDTAKAAGPLQVYKEHAQEVYSVDWSQTRGEQLVVSGSWDQTVKLWDPTVGK 146 Query: 355 FVTAFRGHVADVYQISWSAD-SRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDW 179 + FRGH + +Y WS S S D TL++WD++A ++ +P H E+ + DW Sbjct: 147 SLCTFRGHESIIYSTIWSPHIPGCFASASGDQTLRIWDVKAAGVRIVIPAHQAEILSCDW 206 Query: 178 SPDGEK-VVSGGKDRALKLW 122 E +V+G D +L+ W Sbjct: 207 CKYNENLLVTGAVDCSLRGW 226 Score = 61.2 bits (147), Expect = 2e-09 Identities = 42/142 (29%), Positives = 71/142 (50%), Gaps = 4/142 (2%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPD-GQWLASASFDKSVKLWNGITG 359 SGS D T+ LW+PT+ K GH+ ++ +SP ASAS D+++++W+ Sbjct: 130 SGSWDQTVKLWDPTVGKS-LCTFRGHESIIYSTIWSPHIPGCFASASGDQTLRIWDVKAA 188 Query: 358 KFVTAFRGHVADVYQISW-SADSRLLLSGSKDSTLKVWDIR-ARKLKQDLPGHADEVYAV 185 H A++ W + LL++G+ D +L+ WD+R R+ +L GH + V Sbjct: 189 GVRIVIPAHQAEILSCDWCKYNENLLVTGAVDCSLRGWDLRNVRQPVFELLGHTYAIRRV 248 Query: 184 DWSPDGEKVV-SGGKDRALKLW 122 +SP V+ S D ++ W Sbjct: 249 KFSPFHASVLASCSYDFTVRFW 270 Score = 38.1 bits (87), Expect = 0.016 Identities = 27/100 (27%), Positives = 46/100 (46%), Gaps = 3/100 (3%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSP-DGQWLASASFDKSVKLWN-GIT 362 +G+ D ++ W+ +QP + GH + V FSP LAS S+D +V+ WN Sbjct: 216 TGAVDCSLRGWDLRNVRQPVFELLGHTYAIRRVKFSPFHASVLASCSYDFTVRFWNFSKP 275 Query: 361 GKFVTAFRGHVADVYQISWSADSRLLLSG-SKDSTLKVWD 245 + H + +S S ++ S D T+K++D Sbjct: 276 DSLLETVEHHTEFTCGLDFSLQSPTQVADCSWDETIKIYD 315
>GBB1_RAT (P54311) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 1 (Transducin beta chain 1) Length = 339 Score = 75.9 bits (185), Expect = 7e-14 Identities = 37/116 (31%), Positives = 64/116 (55%) Frame = -2 Query: 469 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 290 + GH ++ F D Q + ++S D + LW+ TG+ T F GH DV +S + D+R Sbjct: 138 LAGHTGYLSCCRFLDDNQ-IVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTR 196 Query: 289 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 L +SG+ D++ K+WD+R +Q GH ++ A+ + P+G +G D +L+ Sbjct: 197 LFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLF 252 Score = 60.1 bits (144), Expect = 4e-09 Identities = 39/140 (27%), Positives = 65/140 (46%), Gaps = 2/140 (1%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SG+ D + LW+ + TGH+ +N + F P+G A+ S D + +L++ + Sbjct: 200 SGACDASAKLWDVR-EGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQ 258 Query: 355 FVTAFRGH--VADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 182 + + + + +S+S RLLL+G D VWD L GH + V + Sbjct: 259 ELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLG 318 Query: 181 WSPDGEKVVSGGKDRALKLW 122 + DG V +G D LK+W Sbjct: 319 VTDDGMAVATGSWDSFLKIW 338 Score = 58.5 bits (140), Expect = 1e-08 Identities = 39/143 (27%), Positives = 68/143 (47%), Gaps = 5/143 (3%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 + S D T LW+ +Q TGH V + +PD + S + D S KLW+ G Sbjct: 158 TSSGDTTCALWDIETGQQTTT-FTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGM 216 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADE-----VY 191 F GH +D+ I + + +GS D+T +++D+RA Q+L ++ + + Sbjct: 217 CRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRA---DQELMTYSHDNIICGIT 273 Query: 190 AVDWSPDGEKVVSGGKDRALKLW 122 +V +S G +++G D +W Sbjct: 274 SVSFSKSGRLLLAGYDDFNCNVW 296 Score = 54.3 bits (129), Expect = 2e-07 Identities = 25/73 (34%), Positives = 37/73 (50%) Frame = -2 Query: 340 RGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEK 161 RGH+A +Y + W DSRLL+S S+D L +WD +P + V ++P G Sbjct: 51 RGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNY 110 Query: 160 VVSGGKDRALKLW 122 V GG D ++ Sbjct: 111 VACGGLDNICSIY 123 Score = 40.8 bits (94), Expect = 0.002 Identities = 33/169 (19%), Positives = 59/169 (34%), Gaps = 45/169 (26%) Frame = -2 Query: 493 ISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAF--------- 341 I + + + GH + +++ D + L SAS D + +W+ T V A Sbjct: 42 IQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMT 101 Query: 340 --------------RGHVADVYQISWS----------------------ADSRLLLSGSK 269 ++ +Y + D +++ S Sbjct: 102 CAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSG 161 Query: 268 DSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 D+T +WDI + GH +V ++ +PD VSG D + KLW Sbjct: 162 DTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLW 210 Score = 36.6 bits (83), Expect = 0.045 Identities = 25/100 (25%), Positives = 44/100 (44%), Gaps = 3/100 (3%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVV---NHVYFSPDGQWLASASFDKSVKLWNGI 365 +GSDD T L++ + + H ++ V FS G+ L + D + +W+ + Sbjct: 242 TGSDDATCRLFD--LRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDAL 299 Query: 364 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD 245 GH V + + D + +GS DS LK+W+ Sbjct: 300 KADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 339
>GBB1_PONPY (Q5R5W8) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 1 (Transducin beta chain 1) Length = 339 Score = 75.9 bits (185), Expect = 7e-14 Identities = 37/116 (31%), Positives = 64/116 (55%) Frame = -2 Query: 469 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 290 + GH ++ F D Q + ++S D + LW+ TG+ T F GH DV +S + D+R Sbjct: 138 LAGHTGYLSCCRFLDDNQ-IVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTR 196 Query: 289 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 L +SG+ D++ K+WD+R +Q GH ++ A+ + P+G +G D +L+ Sbjct: 197 LFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLF 252 Score = 62.0 bits (149), Expect = 1e-09 Identities = 40/140 (28%), Positives = 65/140 (46%), Gaps = 2/140 (1%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SG+ D + LW+ + TGH+ +N + F P+G A+ S D + +L++ + Sbjct: 200 SGACDASAKLWDVR-EGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQ 258 Query: 355 FVTAFRGH--VADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 182 + + + + +S+S RLLL+G D VWD L GH D V + Sbjct: 259 ELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDDRVSCLG 318 Query: 181 WSPDGEKVVSGGKDRALKLW 122 + DG V +G D LK+W Sbjct: 319 VTDDGMAVATGSWDSFLKIW 338 Score = 58.5 bits (140), Expect = 1e-08 Identities = 39/143 (27%), Positives = 68/143 (47%), Gaps = 5/143 (3%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 + S D T LW+ +Q TGH V + +PD + S + D S KLW+ G Sbjct: 158 TSSGDTTCALWDIETGQQTTT-FTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGM 216 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADE-----VY 191 F GH +D+ I + + +GS D+T +++D+RA Q+L ++ + + Sbjct: 217 CRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRA---DQELMTYSHDNIICGIT 273 Query: 190 AVDWSPDGEKVVSGGKDRALKLW 122 +V +S G +++G D +W Sbjct: 274 SVSFSKSGRLLLAGYDDFNCNVW 296 Score = 54.3 bits (129), Expect = 2e-07 Identities = 25/73 (34%), Positives = 37/73 (50%) Frame = -2 Query: 340 RGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEK 161 RGH+A +Y + W DSRLL+S S+D L +WD +P + V ++P G Sbjct: 51 RGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNY 110 Query: 160 VVSGGKDRALKLW 122 V GG D ++ Sbjct: 111 VACGGLDNICSIY 123 Score = 40.8 bits (94), Expect = 0.002 Identities = 33/169 (19%), Positives = 59/169 (34%), Gaps = 45/169 (26%) Frame = -2 Query: 493 ISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAF--------- 341 I + + + GH + +++ D + L SAS D + +W+ T V A Sbjct: 42 IQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMT 101 Query: 340 --------------RGHVADVYQISWS----------------------ADSRLLLSGSK 269 ++ +Y + D +++ S Sbjct: 102 CAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSG 161 Query: 268 DSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 D+T +WDI + GH +V ++ +PD VSG D + KLW Sbjct: 162 DTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLW 210 Score = 36.6 bits (83), Expect = 0.045 Identities = 25/100 (25%), Positives = 44/100 (44%), Gaps = 3/100 (3%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVV---NHVYFSPDGQWLASASFDKSVKLWNGI 365 +GSDD T L++ + + H ++ V FS G+ L + D + +W+ + Sbjct: 242 TGSDDATCRLFD--LRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDAL 299 Query: 364 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD 245 GH V + + D + +GS DS LK+W+ Sbjct: 300 KADRAGVLAGHDDRVSCLGVTDDGMAVATGSWDSFLKIWN 339
>GBB1_MOUSE (P62874) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 1 (Transducin beta chain 1) Length = 339 Score = 75.9 bits (185), Expect = 7e-14 Identities = 37/116 (31%), Positives = 64/116 (55%) Frame = -2 Query: 469 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 290 + GH ++ F D Q + ++S D + LW+ TG+ T F GH DV +S + D+R Sbjct: 138 LAGHTGYLSCCRFLDDNQ-IVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTR 196 Query: 289 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 L +SG+ D++ K+WD+R +Q GH ++ A+ + P+G +G D +L+ Sbjct: 197 LFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLF 252 Score = 60.1 bits (144), Expect = 4e-09 Identities = 39/140 (27%), Positives = 65/140 (46%), Gaps = 2/140 (1%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SG+ D + LW+ + TGH+ +N + F P+G A+ S D + +L++ + Sbjct: 200 SGACDASAKLWDVR-EGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQ 258 Query: 355 FVTAFRGH--VADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 182 + + + + +S+S RLLL+G D VWD L GH + V + Sbjct: 259 ELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLG 318 Query: 181 WSPDGEKVVSGGKDRALKLW 122 + DG V +G D LK+W Sbjct: 319 VTDDGMAVATGSWDSFLKIW 338 Score = 58.5 bits (140), Expect = 1e-08 Identities = 39/143 (27%), Positives = 68/143 (47%), Gaps = 5/143 (3%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 + S D T LW+ +Q TGH V + +PD + S + D S KLW+ G Sbjct: 158 TSSGDTTCALWDIETGQQTTT-FTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGM 216 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADE-----VY 191 F GH +D+ I + + +GS D+T +++D+RA Q+L ++ + + Sbjct: 217 CRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRA---DQELMTYSHDNIICGIT 273 Query: 190 AVDWSPDGEKVVSGGKDRALKLW 122 +V +S G +++G D +W Sbjct: 274 SVSFSKSGRLLLAGYDDFNCNVW 296 Score = 54.3 bits (129), Expect = 2e-07 Identities = 25/73 (34%), Positives = 37/73 (50%) Frame = -2 Query: 340 RGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEK 161 RGH+A +Y + W DSRLL+S S+D L +WD +P + V ++P G Sbjct: 51 RGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNY 110 Query: 160 VVSGGKDRALKLW 122 V GG D ++ Sbjct: 111 VACGGLDNICSIY 123 Score = 40.8 bits (94), Expect = 0.002 Identities = 33/169 (19%), Positives = 59/169 (34%), Gaps = 45/169 (26%) Frame = -2 Query: 493 ISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAF--------- 341 I + + + GH + +++ D + L SAS D + +W+ T V A Sbjct: 42 IQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMT 101 Query: 340 --------------RGHVADVYQISWS----------------------ADSRLLLSGSK 269 ++ +Y + D +++ S Sbjct: 102 CAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSG 161 Query: 268 DSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 D+T +WDI + GH +V ++ +PD VSG D + KLW Sbjct: 162 DTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLW 210 Score = 36.6 bits (83), Expect = 0.045 Identities = 25/100 (25%), Positives = 44/100 (44%), Gaps = 3/100 (3%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVV---NHVYFSPDGQWLASASFDKSVKLWNGI 365 +GSDD T L++ + + H ++ V FS G+ L + D + +W+ + Sbjct: 242 TGSDDATCRLFD--LRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDAL 299 Query: 364 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD 245 GH V + + D + +GS DS LK+W+ Sbjct: 300 KADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 339
>GBB1_HUMAN (P62873) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 1 (Transducin beta chain 1) Length = 339 Score = 75.9 bits (185), Expect = 7e-14 Identities = 37/116 (31%), Positives = 64/116 (55%) Frame = -2 Query: 469 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 290 + GH ++ F D Q + ++S D + LW+ TG+ T F GH DV +S + D+R Sbjct: 138 LAGHTGYLSCCRFLDDNQ-IVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTR 196 Query: 289 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 L +SG+ D++ K+WD+R +Q GH ++ A+ + P+G +G D +L+ Sbjct: 197 LFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLF 252 Score = 60.1 bits (144), Expect = 4e-09 Identities = 39/140 (27%), Positives = 65/140 (46%), Gaps = 2/140 (1%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SG+ D + LW+ + TGH+ +N + F P+G A+ S D + +L++ + Sbjct: 200 SGACDASAKLWDVR-EGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQ 258 Query: 355 FVTAFRGH--VADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 182 + + + + +S+S RLLL+G D VWD L GH + V + Sbjct: 259 ELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLG 318 Query: 181 WSPDGEKVVSGGKDRALKLW 122 + DG V +G D LK+W Sbjct: 319 VTDDGMAVATGSWDSFLKIW 338 Score = 58.5 bits (140), Expect = 1e-08 Identities = 39/143 (27%), Positives = 68/143 (47%), Gaps = 5/143 (3%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 + S D T LW+ +Q TGH V + +PD + S + D S KLW+ G Sbjct: 158 TSSGDTTCALWDIETGQQTTT-FTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGM 216 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADE-----VY 191 F GH +D+ I + + +GS D+T +++D+RA Q+L ++ + + Sbjct: 217 CRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRA---DQELMTYSHDNIICGIT 273 Query: 190 AVDWSPDGEKVVSGGKDRALKLW 122 +V +S G +++G D +W Sbjct: 274 SVSFSKSGRLLLAGYDDFNCNVW 296 Score = 54.3 bits (129), Expect = 2e-07 Identities = 25/73 (34%), Positives = 37/73 (50%) Frame = -2 Query: 340 RGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEK 161 RGH+A +Y + W DSRLL+S S+D L +WD +P + V ++P G Sbjct: 51 RGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNY 110 Query: 160 VVSGGKDRALKLW 122 V GG D ++ Sbjct: 111 VACGGLDNICSIY 123 Score = 40.8 bits (94), Expect = 0.002 Identities = 33/169 (19%), Positives = 59/169 (34%), Gaps = 45/169 (26%) Frame = -2 Query: 493 ISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAF--------- 341 I + + + GH + +++ D + L SAS D + +W+ T V A Sbjct: 42 IQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMT 101 Query: 340 --------------RGHVADVYQISWS----------------------ADSRLLLSGSK 269 ++ +Y + D +++ S Sbjct: 102 CAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSG 161 Query: 268 DSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 D+T +WDI + GH +V ++ +PD VSG D + KLW Sbjct: 162 DTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLW 210 Score = 36.6 bits (83), Expect = 0.045 Identities = 25/100 (25%), Positives = 44/100 (44%), Gaps = 3/100 (3%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVV---NHVYFSPDGQWLASASFDKSVKLWNGI 365 +GSDD T L++ + + H ++ V FS G+ L + D + +W+ + Sbjct: 242 TGSDDATCRLFD--LRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDAL 299 Query: 364 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD 245 GH V + + D + +GS DS LK+W+ Sbjct: 300 KADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 339
>GBB1_CANFA (P62872) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 1 (Transducin beta chain 1) Length = 339 Score = 75.9 bits (185), Expect = 7e-14 Identities = 37/116 (31%), Positives = 64/116 (55%) Frame = -2 Query: 469 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 290 + GH ++ F D Q + ++S D + LW+ TG+ T F GH DV +S + D+R Sbjct: 138 LAGHTGYLSCCRFLDDNQ-IVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTR 196 Query: 289 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 L +SG+ D++ K+WD+R +Q GH ++ A+ + P+G +G D +L+ Sbjct: 197 LFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLF 252 Score = 60.1 bits (144), Expect = 4e-09 Identities = 39/140 (27%), Positives = 65/140 (46%), Gaps = 2/140 (1%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SG+ D + LW+ + TGH+ +N + F P+G A+ S D + +L++ + Sbjct: 200 SGACDASAKLWDVR-EGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQ 258 Query: 355 FVTAFRGH--VADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 182 + + + + +S+S RLLL+G D VWD L GH + V + Sbjct: 259 ELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLG 318 Query: 181 WSPDGEKVVSGGKDRALKLW 122 + DG V +G D LK+W Sbjct: 319 VTDDGMAVATGSWDSFLKIW 338 Score = 58.5 bits (140), Expect = 1e-08 Identities = 39/143 (27%), Positives = 68/143 (47%), Gaps = 5/143 (3%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 + S D T LW+ +Q TGH V + +PD + S + D S KLW+ G Sbjct: 158 TSSGDTTCALWDIETGQQTTT-FTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGM 216 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADE-----VY 191 F GH +D+ I + + +GS D+T +++D+RA Q+L ++ + + Sbjct: 217 CRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRA---DQELMTYSHDNIICGIT 273 Query: 190 AVDWSPDGEKVVSGGKDRALKLW 122 +V +S G +++G D +W Sbjct: 274 SVSFSKSGRLLLAGYDDFNCNVW 296 Score = 54.3 bits (129), Expect = 2e-07 Identities = 25/73 (34%), Positives = 37/73 (50%) Frame = -2 Query: 340 RGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEK 161 RGH+A +Y + W DSRLL+S S+D L +WD +P + V ++P G Sbjct: 51 RGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNY 110 Query: 160 VVSGGKDRALKLW 122 V GG D ++ Sbjct: 111 VACGGLDNICSIY 123 Score = 40.8 bits (94), Expect = 0.002 Identities = 33/169 (19%), Positives = 59/169 (34%), Gaps = 45/169 (26%) Frame = -2 Query: 493 ISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAF--------- 341 I + + + GH + +++ D + L SAS D + +W+ T V A Sbjct: 42 IQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMT 101 Query: 340 --------------RGHVADVYQISWS----------------------ADSRLLLSGSK 269 ++ +Y + D +++ S Sbjct: 102 CAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSG 161 Query: 268 DSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 D+T +WDI + GH +V ++ +PD VSG D + KLW Sbjct: 162 DTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLW 210 Score = 36.6 bits (83), Expect = 0.045 Identities = 25/100 (25%), Positives = 44/100 (44%), Gaps = 3/100 (3%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVV---NHVYFSPDGQWLASASFDKSVKLWNGI 365 +GSDD T L++ + + H ++ V FS G+ L + D + +W+ + Sbjct: 242 TGSDDATCRLFD--LRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDAL 299 Query: 364 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD 245 GH V + + D + +GS DS LK+W+ Sbjct: 300 KADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 339
>GBB1_BOVIN (P62871) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 1 (Transducin beta chain 1) Length = 339 Score = 75.9 bits (185), Expect = 7e-14 Identities = 37/116 (31%), Positives = 64/116 (55%) Frame = -2 Query: 469 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 290 + GH ++ F D Q + ++S D + LW+ TG+ T F GH DV +S + D+R Sbjct: 138 LAGHTGYLSCCRFLDDNQ-IVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTR 196 Query: 289 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 L +SG+ D++ K+WD+R +Q GH ++ A+ + P+G +G D +L+ Sbjct: 197 LFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLF 252 Score = 60.1 bits (144), Expect = 4e-09 Identities = 39/140 (27%), Positives = 65/140 (46%), Gaps = 2/140 (1%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SG+ D + LW+ + TGH+ +N + F P+G A+ S D + +L++ + Sbjct: 200 SGACDASAKLWDVR-EGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQ 258 Query: 355 FVTAFRGH--VADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 182 + + + + +S+S RLLL+G D VWD L GH + V + Sbjct: 259 ELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLG 318 Query: 181 WSPDGEKVVSGGKDRALKLW 122 + DG V +G D LK+W Sbjct: 319 VTDDGMAVATGSWDSFLKIW 338 Score = 58.5 bits (140), Expect = 1e-08 Identities = 39/143 (27%), Positives = 68/143 (47%), Gaps = 5/143 (3%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 + S D T LW+ +Q TGH V + +PD + S + D S KLW+ G Sbjct: 158 TSSGDTTCALWDIETGQQTTT-FTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGM 216 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADE-----VY 191 F GH +D+ I + + +GS D+T +++D+RA Q+L ++ + + Sbjct: 217 CRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRA---DQELMTYSHDNIICGIT 273 Query: 190 AVDWSPDGEKVVSGGKDRALKLW 122 +V +S G +++G D +W Sbjct: 274 SVSFSKSGRLLLAGYDDFNCNVW 296 Score = 54.3 bits (129), Expect = 2e-07 Identities = 25/73 (34%), Positives = 37/73 (50%) Frame = -2 Query: 340 RGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEK 161 RGH+A +Y + W DSRLL+S S+D L +WD +P + V ++P G Sbjct: 51 RGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNY 110 Query: 160 VVSGGKDRALKLW 122 V GG D ++ Sbjct: 111 VACGGLDNICSIY 123 Score = 40.8 bits (94), Expect = 0.002 Identities = 33/169 (19%), Positives = 59/169 (34%), Gaps = 45/169 (26%) Frame = -2 Query: 493 ISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAF--------- 341 I + + + GH + +++ D + L SAS D + +W+ T V A Sbjct: 42 IQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMT 101 Query: 340 --------------RGHVADVYQISWS----------------------ADSRLLLSGSK 269 ++ +Y + D +++ S Sbjct: 102 CAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSG 161 Query: 268 DSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 D+T +WDI + GH +V ++ +PD VSG D + KLW Sbjct: 162 DTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLW 210 Score = 36.6 bits (83), Expect = 0.045 Identities = 25/100 (25%), Positives = 44/100 (44%), Gaps = 3/100 (3%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVV---NHVYFSPDGQWLASASFDKSVKLWNGI 365 +GSDD T L++ + + H ++ V FS G+ L + D + +W+ + Sbjct: 242 TGSDDATCRLFD--LRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDAL 299 Query: 364 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD 245 GH V + + D + +GS DS LK+W+ Sbjct: 300 KADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 339
>TBL1R_MOUSE (Q8BHJ5) F-box-like/WD-repeat protein TBL1XR1 (Transducin beta-like| 1X-related protein 1) (Nuclear receptor corepressor/HDAC3 complex subunit TBLR1) (TBL1-related protein 1) Length = 514 Score = 75.5 bits (184), Expect = 9e-14 Identities = 41/130 (31%), Positives = 64/130 (49%), Gaps = 9/130 (6%) Frame = -2 Query: 484 QPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISW 305 +P GH VN + + P G LAS S D ++K+W+ V + H ++Y I W Sbjct: 340 RPIKTFQGHTNEVNAIKWDPTGNLLASCSDDMTLKIWSMKQDNCVHDLQAHNKEIYTIKW 399 Query: 304 SAD---------SRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVS 152 S + +L S S DST+++WD+ L H + VY+V +SPDG + S Sbjct: 400 SPTGPGTNNPNANLMLASASFDSTVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLAS 459 Query: 151 GGKDRALKLW 122 G D+ + +W Sbjct: 460 GSFDKCVHIW 469 Score = 65.1 bits (157), Expect = 1e-10 Identities = 44/143 (30%), Positives = 66/143 (46%), Gaps = 11/143 (7%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKA--RMTGHQKVVNHVYFSPDGQ---------WLASASFDK 389 S SDD T+ +W KQ + H K + + +SP G LASASFD Sbjct: 366 SCSDDMTLKIWS---MKQDNCVHDLQAHNKEIYTIKWSPTGPGTNNPNANLMLASASFDS 422 Query: 388 SVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPG 209 +V+LW+ G + H VY +++S D R L SGS D + +W+ + L G Sbjct: 423 TVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWNTQTGALVHSYRG 482 Query: 208 HADEVYAVDWSPDGEKVVSGGKD 140 ++ V W+ G+KV + D Sbjct: 483 -TGGIFEVCWNAAGDKVGASASD 504 Score = 64.3 bits (155), Expect = 2e-10 Identities = 37/99 (37%), Positives = 57/99 (57%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 S S D T+ LW+ +T HQ+ V V FSPDG++LAS SFDK V +WN TG Sbjct: 417 SASFDSTVRLWDVDRGICIHT-LTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWNTQTGA 475 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIR 239 V ++RG ++++ W+A + + + D ++ V D+R Sbjct: 476 LVHSYRG-TGGIFEVCWNAAGDKVGASASDGSVCVLDLR 513 Score = 59.3 bits (142), Expect = 7e-09 Identities = 32/105 (30%), Positives = 46/105 (43%), Gaps = 9/105 (8%) Frame = -2 Query: 409 ASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARK 230 AS S D + + + + F+GH +V I W LL S S D TLK+W ++ Sbjct: 323 ASCSTDMCIHVCKLGQDRPIKTFQGHTNEVNAIKWDPTGNLLASCSDDMTLKIWSMKQDN 382 Query: 229 LKQDLPGHADEVYAVDWSPDGE---------KVVSGGKDRALKLW 122 DL H E+Y + WSP G + S D ++LW Sbjct: 383 CVHDLQAHNKEIYTIKWSPTGPGTNNPNANLMLASASFDSTVRLW 427 Score = 56.2 bits (134), Expect = 6e-08 Identities = 30/113 (26%), Positives = 53/113 (46%) Frame = -2 Query: 460 HQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLL 281 H+ + + ++ G ++ SA DK+ +W+ TG+ F H A + W +++ Sbjct: 265 HKGPIFALKWNKKGNFILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQSNN-TFA 323 Query: 280 SGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 S S D + V + + + GH +EV A+ W P G + S D LK+W Sbjct: 324 SCSTDMCIHVCKLGQDRPIKTFQGHTNEVNAIKWDPTGNLLASCSDDMTLKIW 376 Score = 52.4 bits (124), Expect = 8e-07 Identities = 32/130 (24%), Positives = 57/130 (43%), Gaps = 14/130 (10%) Frame = -2 Query: 469 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLW----NGITGKFVTAFRGHV--------- 329 + GH+ V ++P LAS S D + ++W N +G R + Sbjct: 165 LRGHESEVFICAWNPVSDLLASGSGDSTARIWNLSENSTSGPTQLVLRHCIREGGQDVPS 224 Query: 328 -ADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVS 152 DV + W+++ LL +GS D ++W + L L H ++A+ W+ G ++S Sbjct: 225 NKDVTSLDWNSEGTLLATGSYDGFARIW-TKDGNLASTLGQHKGPIFALKWNKKGNFILS 283 Query: 151 GGKDRALKLW 122 G D+ +W Sbjct: 284 AGVDKTTIIW 293
>TBL1R_HUMAN (Q9BZK7) F-box-like/WD-repeat protein TBL1XR1 (Transducin beta-like| 1X-related protein 1) (Nuclear receptor corepressor/HDAC3 complex subunit TBLR1) (TBL1-related protein 1) Length = 514 Score = 75.5 bits (184), Expect = 9e-14 Identities = 41/130 (31%), Positives = 64/130 (49%), Gaps = 9/130 (6%) Frame = -2 Query: 484 QPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISW 305 +P GH VN + + P G LAS S D ++K+W+ V + H ++Y I W Sbjct: 340 RPIKTFQGHTNEVNAIKWDPTGNLLASCSDDMTLKIWSMKQDNCVHDLQAHNKEIYTIKW 399 Query: 304 SAD---------SRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVS 152 S + +L S S DST+++WD+ L H + VY+V +SPDG + S Sbjct: 400 SPTGPGTNNPNANLMLASASFDSTVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLAS 459 Query: 151 GGKDRALKLW 122 G D+ + +W Sbjct: 460 GSFDKCVHIW 469 Score = 65.1 bits (157), Expect = 1e-10 Identities = 44/143 (30%), Positives = 66/143 (46%), Gaps = 11/143 (7%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKA--RMTGHQKVVNHVYFSPDGQ---------WLASASFDK 389 S SDD T+ +W KQ + H K + + +SP G LASASFD Sbjct: 366 SCSDDMTLKIWS---MKQDNCVHDLQAHNKEIYTIKWSPTGPGTNNPNANLMLASASFDS 422 Query: 388 SVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPG 209 +V+LW+ G + H VY +++S D R L SGS D + +W+ + L G Sbjct: 423 TVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWNTQTGALVHSYRG 482 Query: 208 HADEVYAVDWSPDGEKVVSGGKD 140 ++ V W+ G+KV + D Sbjct: 483 -TGGIFEVCWNAAGDKVGASASD 504 Score = 64.3 bits (155), Expect = 2e-10 Identities = 37/99 (37%), Positives = 57/99 (57%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 S S D T+ LW+ +T HQ+ V V FSPDG++LAS SFDK V +WN TG Sbjct: 417 SASFDSTVRLWDVDRGICIHT-LTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWNTQTGA 475 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIR 239 V ++RG ++++ W+A + + + D ++ V D+R Sbjct: 476 LVHSYRG-TGGIFEVCWNAAGDKVGASASDGSVCVLDLR 513 Score = 59.3 bits (142), Expect = 7e-09 Identities = 32/105 (30%), Positives = 46/105 (43%), Gaps = 9/105 (8%) Frame = -2 Query: 409 ASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARK 230 AS S D + + + + F+GH +V I W LL S S D TLK+W ++ Sbjct: 323 ASCSTDMCIHVCKLGQDRPIKTFQGHTNEVNAIKWDPTGNLLASCSDDMTLKIWSMKQDN 382 Query: 229 LKQDLPGHADEVYAVDWSPDGE---------KVVSGGKDRALKLW 122 DL H E+Y + WSP G + S D ++LW Sbjct: 383 CVHDLQAHNKEIYTIKWSPTGPGTNNPNANLMLASASFDSTVRLW 427 Score = 56.2 bits (134), Expect = 6e-08 Identities = 30/113 (26%), Positives = 53/113 (46%) Frame = -2 Query: 460 HQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLL 281 H+ + + ++ G ++ SA DK+ +W+ TG+ F H A + W +++ Sbjct: 265 HKGPIFALKWNKKGNFILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQSNN-TFA 323 Query: 280 SGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 S S D + V + + + GH +EV A+ W P G + S D LK+W Sbjct: 324 SCSTDMCIHVCKLGQDRPIKTFQGHTNEVNAIKWDPTGNLLASCSDDMTLKIW 376 Score = 52.8 bits (125), Expect = 6e-07 Identities = 32/130 (24%), Positives = 57/130 (43%), Gaps = 14/130 (10%) Frame = -2 Query: 469 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLW----NGITGKFVTAFRGHV--------- 329 + GH+ V ++P LAS S D + ++W N +G R + Sbjct: 165 LRGHESEVFICAWNPVSDLLASGSGDSTARIWNLSENSTSGSTQLVLRHCIREGGQDVPS 224 Query: 328 -ADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVS 152 DV + W+++ LL +GS D ++W + L L H ++A+ W+ G ++S Sbjct: 225 NKDVTSLDWNSEGTLLATGSYDGFARIW-TKDGNLASTLGQHKGPIFALKWNKKGNFILS 283 Query: 151 GGKDRALKLW 122 G D+ +W Sbjct: 284 AGVDKTTIIW 293
>PRP46_ASHGO (Q75BY3) Pre-mRNA-splicing factor PRP46 (Pre-mRNA-processing| protein 46) Length = 425 Score = 75.5 bits (184), Expect = 9e-14 Identities = 44/138 (31%), Positives = 68/138 (49%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 +GS+D T+ +W+ K K + GH V + S ++ SAS DK VK W+ Sbjct: 131 TGSNDSTIRVWDLATGKL-KVTLQGHIMTVRDICISARHPYMFSASQDKLVKCWDLERNT 189 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 V F G ++ V+ + L++S +DS ++VWDIR+R L GH + V Sbjct: 190 VVRDFHGTLSGVHSVDLHPSLDLIVSAGRDSVVRVWDIRSRSCVLTLAGHRGPINKVRCL 249 Query: 175 PDGEKVVSGGKDRALKLW 122 P ++VS D +KLW Sbjct: 250 PVDPQIVSCSTDATVKLW 267 Score = 75.5 bits (184), Expect = 9e-14 Identities = 41/145 (28%), Positives = 71/145 (48%), Gaps = 9/145 (6%) Frame = -2 Query: 529 SDDFTMFLWEPTISKQPKAR--------MTGHQKVVNHVYFSP-DGQWLASASFDKSVKL 377 +D + +E +S++P+ + GH V V P D W A+ S D ++++ Sbjct: 81 ADTSALARYEEVVSQKPQWHAPWKLTRVINGHTGWVRCVCVDPVDNAWFATGSNDSTIRV 140 Query: 376 WNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADE 197 W+ TGK +GH+ V I SA + S S+D +K WD+ + +D G Sbjct: 141 WDLATGKLKVTLQGHIMTVRDICISARHPYMFSASQDKLVKCWDLERNTVVRDFHGTLSG 200 Query: 196 VYAVDWSPDGEKVVSGGKDRALKLW 122 V++VD P + +VS G+D +++W Sbjct: 201 VHSVDLHPSLDLIVSAGRDSVVRVW 225 Score = 35.4 bits (80), Expect = 0.10 Identities = 27/103 (26%), Positives = 45/103 (43%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 S D + +W+ S+ + GH+ +N V P + S S D +VKLW+ + GK Sbjct: 215 SAGRDSVVRVWDIR-SRSCVLTLAGHRGPINKVRCLPVDPQIVSCSTDATVKLWDLVAGK 273 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKL 227 + H +V ++++ S D DIR+ KL Sbjct: 274 PMKTLTHHKRNVRDLAFNPTEFSFASACTD------DIRSWKL 310
>PRP46_SCHPO (O13615) Pre-mRNA-splicing factor prp46 (Pre-mRNA-processing| protein 5) (Complexed with cdc5 protein 1) Length = 473 Score = 75.5 bits (184), Expect = 9e-14 Identities = 42/138 (30%), Positives = 70/138 (50%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 +G+ D T+ +W+ S K +TGH V + SP +L S DK VK W+ T K Sbjct: 180 TGAGDRTIKIWD-LASGVLKLTLTGHIATVRGLAVSPRHPYLFSCGEDKMVKCWDLETNK 238 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 + + GH++ VY + +L++ +D+ +VWD+R R+ L GH V ++ Sbjct: 239 VIRHYHGHLSGVYALKLHPTLDVLVTAGRDAVARVWDMRTRQNVHVLSGHKSTVASLAVQ 298 Query: 175 PDGEKVVSGGKDRALKLW 122 +VV+G D ++LW Sbjct: 299 EFDPQVVTGSMDSTIRLW 316 Score = 68.9 bits (167), Expect = 8e-12 Identities = 33/116 (28%), Positives = 58/116 (50%) Frame = -2 Query: 469 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 290 ++GH V V P QW + + D+++K+W+ +G GH+A V ++ S Sbjct: 159 ISGHLGWVRCVDVEPGNQWFCTGAGDRTIKIWDLASGVLKLTLTGHIATVRGLAVSPRHP 218 Query: 289 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 L S +D +K WD+ K+ + GH VYA+ P + +V+ G+D ++W Sbjct: 219 YLFSCGEDKMVKCWDLETNKVIRHYHGHLSGVYALKLHPTLDVLVTAGRDAVARVW 274 Score = 39.3 bits (90), Expect = 0.007 Identities = 27/116 (23%), Positives = 48/116 (41%) Frame = -2 Query: 469 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 290 ++GH+ V + + + S D +++LW+ GK +T H V +S D Sbjct: 285 LSGHKSTVASLAVQEFDPQVVTGSMDSTIRLWDLAAGKTLTTLTHHKKTVRALSLHPDEF 344 Query: 289 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 SGS D+ +K W + GH V + + D + SG + ++ W Sbjct: 345 TFASGSSDN-IKHWKFPEGAFMGNFEGHNAIVNTLSINSD-NVMFSGADNGSMCFW 398
>WDR57_MOUSE (Q6PE01) WD-repeat protein 57| Length = 358 Score = 75.5 bits (184), Expect = 9e-14 Identities = 44/139 (31%), Positives = 72/139 (51%), Gaps = 1/139 (0%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 S D + LW A + GH V ++++ DG L SAS DK+V +W+ TG+ Sbjct: 84 SAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYNTDGSMLFSASTDKTVAVWDSETGE 143 Query: 355 FVTAFRGHVADVYQ-ISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDW 179 V +GH + V +L+ +GS D T+K+WDIR + Q + +V AV + Sbjct: 144 RVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWDIRKKAAVQTFQ-NTYQVLAVTF 202 Query: 178 SPDGEKVVSGGKDRALKLW 122 + ++++SGG D +K+W Sbjct: 203 NDTSDQIISGGIDNDIKVW 221 Score = 74.7 bits (182), Expect = 2e-13 Identities = 43/146 (29%), Positives = 70/146 (47%), Gaps = 8/146 (5%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 +GSDD T+ LW+ I K+ + + V V F+ + S D +K+W+ K Sbjct: 170 TGSDDGTVKLWD--IRKKAAVQTFQNTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNK 227 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQ--------DLPGHAD 200 RGH V +S S++ LLS + D+T++VWD+R K+ ++ Sbjct: 228 LTYTMRGHADSVTGLSLSSEGSYLLSNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNFEK 287 Query: 199 EVYAVDWSPDGEKVVSGGKDRALKLW 122 + WSPDG K+ +G DR + +W Sbjct: 288 NLLRCSWSPDGSKIAAGSADRFVYVW 313 Score = 73.9 bits (180), Expect = 3e-13 Identities = 44/139 (31%), Positives = 74/139 (53%), Gaps = 1/139 (0%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDG-QWLASASFDKSVKLWNGITG 359 S S D T+ +W+ ++ K R+ GH VN Y + G Q + + S D +VKLW+ Sbjct: 127 SASTDKTVAVWDSETGERVK-RLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWDIRKK 185 Query: 358 KFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDW 179 V F+ + V ++++ S ++SG D+ +KVWD+R KL + GHAD V + Sbjct: 186 AAVQTFQ-NTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADSVTGLSL 244 Query: 178 SPDGEKVVSGGKDRALKLW 122 S +G ++S D +++W Sbjct: 245 SSEGSYLLSNAMDNTVRVW 263 Score = 67.0 bits (162), Expect = 3e-11 Identities = 41/123 (33%), Positives = 63/123 (51%), Gaps = 3/123 (2%) Frame = -2 Query: 481 PKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWN--GITGKFVTAFRGHVADVYQIS 308 P ++GH+ V F P+G LASA FD+ + LWN G + T +GH V ++ Sbjct: 59 PIMLLSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCDNYAT-LKGHSGAVMELH 117 Query: 307 WSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVV-SGGKDRAL 131 ++ D +L S S D T+ VWD + + L GH V + + G ++V +G D + Sbjct: 118 YNTDGSMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTV 177 Query: 130 KLW 122 KLW Sbjct: 178 KLW 180 Score = 66.6 bits (161), Expect = 4e-11 Identities = 42/143 (29%), Positives = 71/143 (49%), Gaps = 8/143 (5%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWN----G 368 SG D + +W+ +K M GH V + S +G +L S + D +V++W+ Sbjct: 211 SGGIDNDIKVWDLRQNKLTYT-MRGHADSVTGLSLSSEGSYLLSNAMDNTVRVWDVRPFA 269 Query: 367 ITGKFVTAFRGHV----ADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHAD 200 + V F+G+V ++ + SWS D + +GS D + VWD +R++ LPGHA Sbjct: 270 PKERCVKIFQGNVHNFEKNLLRCSWSPDGSKIAAGSADRFVYVWDTTSRRVLYKLPGHAG 329 Query: 199 EVYAVDWSPDGEKVVSGGKDRAL 131 + V + PD ++S D+ L Sbjct: 330 SINEVAFHPDEPIILSASSDKRL 352 Score = 42.0 bits (97), Expect = 0.001 Identities = 18/65 (27%), Positives = 37/65 (56%) Frame = -2 Query: 433 FSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLK 254 +SPDG +A+ S D+ V +W+ + + + GH + ++++ D ++LS S D L Sbjct: 294 WSPDGSKIAAGSADRFVYVWDTTSRRVLYKLPGHAGSINEVAFHPDEPIILSASSDKRLY 353 Query: 253 VWDIR 239 + +I+ Sbjct: 354 MGEIQ 358
>APAF_BRARE (Q9I9H8) Apoptotic protease-activating factor 1 (Apaf-1)| Length = 1261 Score = 75.5 bits (184), Expect = 9e-14 Identities = 46/139 (33%), Positives = 76/139 (54%), Gaps = 2/139 (1%) Frame = -2 Query: 532 GSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKF 353 GS+D T+ + E SK +++GH K V+H F+ D + L ++S D ++++W TG+ Sbjct: 984 GSEDGTVQVIEVPSSKA-SVKLSGHTKTVHHCQFTDDCEILITSSEDSTIRVWKWRTGEC 1042 Query: 352 VTAFRGHVADV--YQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDW 179 + +GH+ V + + S+ S L S S D T+KVWD+ ++ QDL H V + D Sbjct: 1043 M-VLQGHMEPVRKFHLLSSSSSPHLFSWSFDGTVKVWDLTRGQMLQDLVCHEGAVLSCDV 1101 Query: 178 SPDGEKVVSGGKDRALKLW 122 S DG + +R K+W Sbjct: 1102 SSDGRLFATTSANRTAKVW 1120 Score = 58.2 bits (139), Expect = 1e-08 Identities = 48/189 (25%), Positives = 77/189 (40%), Gaps = 53/189 (28%) Frame = -2 Query: 529 SDDFTMF-LWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKL-------- 377 +D FT LW P K + M GH + VNH FSP+ +LA++S D S+KL Sbjct: 724 NDKFTNTRLWNPN-KKTSQNTMFGHMEPVNHCCFSPNDLYLATSSSDGSLKLFEVSSANE 782 Query: 376 WNGIT--GKFVTAFRGHVADVYQISWSADSRLLLSGSKDS-------------------- 263 W I F + A V +WSAD ++ ++++ Sbjct: 783 WKSIDVDSFFPESDEEIKAMVKCSTWSADGSQIICAARNTVFVFDVETSDLLLKLKTSRL 842 Query: 262 ----------------------TLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSG 149 T+++W+ + K K + GH V+ V +SPDG ++S Sbjct: 843 STIQFCHACPNSSLLAVALSHYTVELWNFESSKKKAECSGHLSWVHCVQFSPDGSLLLSS 902 Query: 148 GKDRALKLW 122 D+ ++LW Sbjct: 903 SDDQTIRLW 911 Score = 57.8 bits (138), Expect = 2e-08 Identities = 40/140 (28%), Positives = 68/140 (48%), Gaps = 2/140 (1%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVN--HVYFSPDGQWLASASFDKSVKLWNGIT 362 + S+D T+ +W+ + + GH + V H+ S L S SFD +VK+W+ Sbjct: 1025 TSSEDSTIRVWKWRTGECMV--LQGHMEPVRKFHLLSSSSSPHLFSWSFDGTVKVWDLTR 1082 Query: 361 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 182 G+ + H V S+D RL + S + T KVW + K+ L GH D V + Sbjct: 1083 GQMLQDLVCHEGAVLSCDVSSDGRLFATTSANRTAKVWSSASWKMLFLLEGHKDCVRSCR 1142 Query: 181 WSPDGEKVVSGGKDRALKLW 122 +S D +++ +G + ++LW Sbjct: 1143 FSWDNKRLATGDDNGEIRLW 1162 Score = 53.9 bits (128), Expect = 3e-07 Identities = 41/173 (23%), Positives = 73/173 (42%), Gaps = 40/173 (23%) Frame = -2 Query: 520 FTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLW----------- 374 +T+ LW SK+ KA +GH V+ V FSPDG L S+S D++++LW Sbjct: 864 YTVELWNFESSKK-KAECSGHLSWVHCVQFSPDGSLLLSSSDDQTIRLWETDRVHTSSAV 922 Query: 373 -----------------------------NGITGKFVTAFRGHVADVYQISWSADSRLLL 281 +G TG V + + S ++ + Sbjct: 923 ALKRDTDVLSSHSDATIIAPDSSNRLQVLSGSTGAVVLESEELSSRIRCSCISRNAAFVA 982 Query: 280 SGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 GS+D T++V ++ + K L GH V+ ++ D E +++ +D +++W Sbjct: 983 LGSEDGTVQVIEVPSSKASVKLSGHTKTVHHCQFTDDCEILITSSEDSTIRVW 1035 Score = 49.7 bits (117), Expect = 5e-06 Identities = 37/132 (28%), Positives = 61/132 (46%), Gaps = 9/132 (6%) Frame = -2 Query: 517 TMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFR 338 T+F+++ S T + + P+ LA A +V+LWN + K Sbjct: 822 TVFVFDVETSDLLLKLKTSRLSTIQFCHACPNSSLLAVALSHYTVELWNFESSKKKAECS 881 Query: 337 GHVADVYQISWSADSRLLLSGSKDSTLKVWDI------RARKLKQD---LPGHADEVYAV 185 GH++ V+ + +S D LLLS S D T+++W+ A LK+D L H+D Sbjct: 882 GHLSWVHCVQFSPDGSLLLSSSDDQTIRLWETDRVHTSSAVALKRDTDVLSSHSDATIIA 941 Query: 184 DWSPDGEKVVSG 149 S + +V+SG Sbjct: 942 PDSSNRLQVLSG 953 Score = 46.2 bits (108), Expect = 6e-05 Identities = 30/121 (24%), Positives = 57/121 (47%), Gaps = 5/121 (4%) Frame = -2 Query: 469 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFR-GHVADVYQISWSADS 293 + H++ V FSPD + +A+ + D+ VKLWN G + F H + ++ Sbjct: 655 LQAHEEDVLCCAFSPDDRHIATCASDRKVKLWNVERGVLIREFEVEHEEQINHCQFTNTG 714 Query: 292 RLLL----SGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKL 125 R +L S K + ++W+ + + + GH + V +SP+ + + D +LKL Sbjct: 715 RRVLLATCSNDKFTNTRLWNPNKKTSQNTMFGHMEPVNHCCFSPNDLYLATSSSDGSLKL 774 Query: 124 W 122 + Sbjct: 775 F 775 Score = 45.4 bits (106), Expect = 1e-04 Identities = 35/137 (25%), Positives = 62/137 (45%), Gaps = 9/137 (6%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 S S D T+ +W+ T Q + H+ V S DG+ A+ S +++ K+W+ + K Sbjct: 1068 SWSFDGTVKVWDLTRG-QMLQDLVCHEGAVLSCDVSSDGRLFATTSANRTAKVWSSASWK 1126 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPG---------HA 203 + GH V +S D++ L +G + +++W + L + P HA Sbjct: 1127 MLFLLEGHKDCVRSCRFSWDNKRLATGDDNGEIRLWSMLDGALLKICPRDTKDSMNSYHA 1186 Query: 202 DEVYAVDWSPDGEKVVS 152 V + +SPD +VS Sbjct: 1187 GWVTDLHFSPDNRVLVS 1203 Score = 38.5 bits (88), Expect = 0.012 Identities = 27/105 (25%), Positives = 50/105 (47%), Gaps = 2/105 (1%) Frame = -2 Query: 430 SPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKV 251 S + ++A S D +V++ + K GH V+ ++ D +L++ S+DST++V Sbjct: 975 SRNAAFVALGSEDGTVQVIEVPSSKASVKLSGHTKTVHHCQFTDDCEILITSSEDSTIRV 1034 Query: 250 WDIRARKLKQDLPGHADEV--YAVDWSPDGEKVVSGGKDRALKLW 122 W R + L GH + V + + S + S D +K+W Sbjct: 1035 WKWRTGEC-MVLQGHMEPVRKFHLLSSSSSPHLFSWSFDGTVKVW 1078 Score = 37.4 bits (85), Expect = 0.027 Identities = 19/71 (26%), Positives = 32/71 (45%) Frame = -2 Query: 334 HVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVV 155 H VY +S D + S L+V+ + + +L H ++V +SPD + Sbjct: 616 HQGAVYYACFSKDGSKIASCGASKALRVFKSTSGEKLLELQAHEEDVLCCAFSPDDRHIA 675 Query: 154 SGGKDRALKLW 122 + DR +KLW Sbjct: 676 TCASDRKVKLW 686
>GBB1_CRIGR (Q6TMK6) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 1 (Transducin beta chain 1) Length = 339 Score = 75.5 bits (184), Expect = 9e-14 Identities = 37/116 (31%), Positives = 64/116 (55%) Frame = -2 Query: 469 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 290 + GH ++ F D Q + ++S D + LW+ TG+ T F GH DV +S + D+R Sbjct: 138 LAGHTGYLSCCRFLNDNQ-IVTSSEDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTR 196 Query: 289 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 L +SG+ D++ K+WD+R +Q GH ++ A+ + P+G +G D +L+ Sbjct: 197 LFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLF 252 Score = 60.1 bits (144), Expect = 4e-09 Identities = 39/140 (27%), Positives = 65/140 (46%), Gaps = 2/140 (1%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SG+ D + LW+ + TGH+ +N + F P+G A+ S D + +L++ + Sbjct: 200 SGACDASAKLWDVR-EGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQ 258 Query: 355 FVTAFRGH--VADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 182 + + + + +S+S RLLL+G D VWD L GH + V + Sbjct: 259 ELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLG 318 Query: 181 WSPDGEKVVSGGKDRALKLW 122 + DG V +G D LK+W Sbjct: 319 VTDDGMAVATGSWDSFLKIW 338 Score = 59.7 bits (143), Expect = 5e-09 Identities = 39/143 (27%), Positives = 69/143 (48%), Gaps = 5/143 (3%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 + S+D T LW+ +Q TGH V + +PD + S + D S KLW+ G Sbjct: 158 TSSEDTTCALWDIETGQQTTT-FTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGM 216 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADE-----VY 191 F GH +D+ I + + +GS D+T +++D+RA Q+L ++ + + Sbjct: 217 CRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRA---DQELMTYSHDNIICGIT 273 Query: 190 AVDWSPDGEKVVSGGKDRALKLW 122 +V +S G +++G D +W Sbjct: 274 SVSFSKSGRLLLAGYDDFNCNVW 296 Score = 54.3 bits (129), Expect = 2e-07 Identities = 25/73 (34%), Positives = 37/73 (50%) Frame = -2 Query: 340 RGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEK 161 RGH+A +Y + W DSRLL+S S+D L +WD +P + V ++P G Sbjct: 51 RGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNY 110 Query: 160 VVSGGKDRALKLW 122 V GG D ++ Sbjct: 111 VACGGLDNICSIY 123 Score = 40.8 bits (94), Expect = 0.002 Identities = 35/170 (20%), Positives = 62/170 (36%), Gaps = 46/170 (27%) Frame = -2 Query: 493 ISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT---------------- 362 I + + + GH + +++ D + L SAS D + +W+ T Sbjct: 42 IQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMT 101 Query: 361 ------GKFVTA------------------------FRGHVADVYQISWSADSRLLLSGS 272 G +V GH + + D++++ S S Sbjct: 102 CAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLNDNQIVTS-S 160 Query: 271 KDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 +D+T +WDI + GH +V ++ +PD VSG D + KLW Sbjct: 161 EDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLW 210 Score = 36.6 bits (83), Expect = 0.045 Identities = 25/100 (25%), Positives = 44/100 (44%), Gaps = 3/100 (3%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVV---NHVYFSPDGQWLASASFDKSVKLWNGI 365 +GSDD T L++ + + H ++ V FS G+ L + D + +W+ + Sbjct: 242 TGSDDATCRLFD--LRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDAL 299 Query: 364 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD 245 GH V + + D + +GS DS LK+W+ Sbjct: 300 KADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 339
>WDR57_PONPY (Q5RF51) WD-repeat protein 57| Length = 357 Score = 75.1 bits (183), Expect = 1e-13 Identities = 43/146 (29%), Positives = 71/146 (48%), Gaps = 8/146 (5%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 +GSDD T+ LW+ I K+ + + V V F+ + S D +K+W+ K Sbjct: 169 TGSDDGTVKLWD--IRKKAAIQTFQNTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNK 226 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQ--------DLPGHAD 200 RGH V +S S++ LLS + D+T++VWD+R K+ ++ Sbjct: 227 LTYTMRGHADSVTGLSLSSEGSYLLSNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNFEK 286 Query: 199 EVYAVDWSPDGEKVVSGGKDRALKLW 122 + WSPDG K+ +G DR++ +W Sbjct: 287 NLLRCSWSPDGSKIAAGSADRSVCVW 312 Score = 73.6 bits (179), Expect = 3e-13 Identities = 43/139 (30%), Positives = 74/139 (53%), Gaps = 1/139 (0%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDG-QWLASASFDKSVKLWNGITG 359 S S D T+ +W+ ++ K R+ GH VN Y + G Q + + S D +VKLW+ Sbjct: 126 SASTDKTVAVWDSETGERVK-RLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWDIRKK 184 Query: 358 KFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDW 179 + F+ + V ++++ S ++SG D+ +KVWD+R KL + GHAD V + Sbjct: 185 AAIQTFQ-NTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADSVTGLSL 243 Query: 178 SPDGEKVVSGGKDRALKLW 122 S +G ++S D +++W Sbjct: 244 SSEGSYLLSNAMDNTVRVW 262 Score = 72.0 bits (175), Expect = 1e-12 Identities = 43/139 (30%), Positives = 72/139 (51%), Gaps = 1/139 (0%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 S D + LW A + G+ V ++++ DG L SAS DK+V +W+ TG+ Sbjct: 83 SAGFDRLILLWNVYGDCGNYATLKGYSGAVMELHYNTDGSMLFSASTDKTVAVWDSETGE 142 Query: 355 FVTAFRGHVADVYQ-ISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDW 179 V +GH + V +L+ +GS D T+K+WDIR + Q + +V AV + Sbjct: 143 RVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWDIRKKAAIQTFQ-NTYQVLAVTF 201 Query: 178 SPDGEKVVSGGKDRALKLW 122 + ++++SGG D +K+W Sbjct: 202 NDTSDQIISGGIDNDIKVW 220 Score = 68.6 bits (166), Expect = 1e-11 Identities = 42/143 (29%), Positives = 72/143 (50%), Gaps = 8/143 (5%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWN----G 368 SG D + +W+ +K M GH V + S +G +L S + D +V++W+ Sbjct: 210 SGGIDNDIKVWDLRQNKLTYT-MRGHADSVTGLSLSSEGSYLLSNAMDNTVRVWDVRPFA 268 Query: 367 ITGKFVTAFRGHV----ADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHAD 200 + V F+G+V ++ + SWS D + +GS D ++ VWD +R++ LPGHA Sbjct: 269 PKERCVKIFQGNVHNFEKNLLRCSWSPDGSKIAAGSADRSVCVWDTTSRRILYKLPGHAG 328 Query: 199 EVYAVDWSPDGEKVVSGGKDRAL 131 + V + PD ++S D+ L Sbjct: 329 SINEVAFHPDEPIIISASSDKRL 351 Score = 67.4 bits (163), Expect = 2e-11 Identities = 41/123 (33%), Positives = 64/123 (52%), Gaps = 3/123 (2%) Frame = -2 Query: 481 PKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWN--GITGKFVTAFRGHVADVYQIS 308 P ++GH+ V F P+G LASA FD+ + LWN G G + T +G+ V ++ Sbjct: 58 PIMLLSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCGNYAT-LKGYSGAVMELH 116 Query: 307 WSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVV-SGGKDRAL 131 ++ D +L S S D T+ VWD + + L GH V + + G ++V +G D + Sbjct: 117 YNTDGSMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTV 176 Query: 130 KLW 122 KLW Sbjct: 177 KLW 179 Score = 43.5 bits (101), Expect = 4e-04 Identities = 18/65 (27%), Positives = 38/65 (58%) Frame = -2 Query: 433 FSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLK 254 +SPDG +A+ S D+SV +W+ + + + GH + ++++ D +++S S D L Sbjct: 293 WSPDGSKIAAGSADRSVCVWDTTSRRILYKLPGHAGSINEVAFHPDEPIIISASSDKRLY 352 Query: 253 VWDIR 239 + +I+ Sbjct: 353 MGEIQ 357
>WDR57_HUMAN (Q96DI7) WD-repeat protein 57 (Prp8-binding protein) (hPRP8BP) (U5| snRNP-specific 40 kDa protein) (38 kDa splicing factor) Length = 357 Score = 75.1 bits (183), Expect = 1e-13 Identities = 44/139 (31%), Positives = 72/139 (51%), Gaps = 1/139 (0%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 S D + LW A + GH V ++++ DG L SAS DK+V +W+ TG+ Sbjct: 83 SAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYNTDGSMLFSASTDKTVAVWDSETGE 142 Query: 355 FVTAFRGHVADVYQ-ISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDW 179 V +GH + V +L+ +GS D T+K+WDIR + Q + +V AV + Sbjct: 143 RVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWDIRKKAAIQTFQ-NTYQVLAVTF 201 Query: 178 SPDGEKVVSGGKDRALKLW 122 + ++++SGG D +K+W Sbjct: 202 NDTSDQIISGGIDNDIKVW 220 Score = 74.3 bits (181), Expect = 2e-13 Identities = 43/146 (29%), Positives = 70/146 (47%), Gaps = 8/146 (5%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 +GSDD T+ LW+ I K+ + + V V F+ + S D +K+W+ K Sbjct: 169 TGSDDGTVKLWD--IRKKAAIQTFQNTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNK 226 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQ--------DLPGHAD 200 RGH V +S S++ LLS + D+T++VWD+R K+ ++ Sbjct: 227 LTYTMRGHADSVTGLSLSSEGSYLLSNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNFEK 286 Query: 199 EVYAVDWSPDGEKVVSGGKDRALKLW 122 + WSPDG K+ +G DR + +W Sbjct: 287 NLLRCSWSPDGSKIAAGSADRFVYVW 312 Score = 73.6 bits (179), Expect = 3e-13 Identities = 43/139 (30%), Positives = 74/139 (53%), Gaps = 1/139 (0%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDG-QWLASASFDKSVKLWNGITG 359 S S D T+ +W+ ++ K R+ GH VN Y + G Q + + S D +VKLW+ Sbjct: 126 SASTDKTVAVWDSETGERVK-RLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWDIRKK 184 Query: 358 KFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDW 179 + F+ + V ++++ S ++SG D+ +KVWD+R KL + GHAD V + Sbjct: 185 AAIQTFQ-NTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADSVTGLSL 243 Query: 178 SPDGEKVVSGGKDRALKLW 122 S +G ++S D +++W Sbjct: 244 SSEGSYLLSNAMDNTVRVW 262 Score = 67.8 bits (164), Expect = 2e-11 Identities = 42/143 (29%), Positives = 71/143 (49%), Gaps = 8/143 (5%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWN----G 368 SG D + +W+ +K M GH V + S +G +L S + D +V++W+ Sbjct: 210 SGGIDNDIKVWDLRQNKLTYT-MRGHADSVTGLSLSSEGSYLLSNAMDNTVRVWDVRPFA 268 Query: 367 ITGKFVTAFRGHV----ADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHAD 200 + V F+G+V ++ + SWS D + +GS D + VWD +R++ LPGHA Sbjct: 269 PKERCVKIFQGNVHNFEKNLLRCSWSPDGSKIAAGSADRFVYVWDTTSRRILYKLPGHAG 328 Query: 199 EVYAVDWSPDGEKVVSGGKDRAL 131 + V + PD ++S D+ L Sbjct: 329 SINEVAFHPDEPIIISASSDKRL 351 Score = 67.0 bits (162), Expect = 3e-11 Identities = 41/123 (33%), Positives = 63/123 (51%), Gaps = 3/123 (2%) Frame = -2 Query: 481 PKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWN--GITGKFVTAFRGHVADVYQIS 308 P ++GH+ V F P+G LASA FD+ + LWN G + T +GH V ++ Sbjct: 58 PIMLLSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCDNYAT-LKGHSGAVMELH 116 Query: 307 WSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVV-SGGKDRAL 131 ++ D +L S S D T+ VWD + + L GH V + + G ++V +G D + Sbjct: 117 YNTDGSMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTV 176 Query: 130 KLW 122 KLW Sbjct: 177 KLW 179 Score = 41.6 bits (96), Expect = 0.001 Identities = 17/65 (26%), Positives = 37/65 (56%) Frame = -2 Query: 433 FSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLK 254 +SPDG +A+ S D+ V +W+ + + + GH + ++++ D +++S S D L Sbjct: 293 WSPDGSKIAAGSADRFVYVWDTTSRRILYKLPGHAGSINEVAFHPDEPIIISASSDKRLY 352 Query: 253 VWDIR 239 + +I+ Sbjct: 353 MGEIQ 357
>GBB_LYMST (Q08706) Guanine nucleotide-binding protein beta subunit| Length = 341 Score = 75.1 bits (183), Expect = 1e-13 Identities = 38/116 (32%), Positives = 62/116 (53%) Frame = -2 Query: 469 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 290 + GH ++ F D + ++S D S LW+ TG+ T+F GH DV +S S D R Sbjct: 140 LPGHTGYLSCCRFIDDNS-IVTSSGDMSCALWDIETGQQTTSFTGHTGDVMSLSTSPDFR 198 Query: 289 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 +SG+ D++ K+WD+R KQ GH ++ A+ + P+G +G D +L+ Sbjct: 199 TFVSGACDASAKLWDVRDGMCKQTFSGHESDINAITYFPNGHAFATGSDDATCRLF 254 Score = 59.3 bits (142), Expect = 7e-09 Identities = 47/182 (25%), Positives = 73/182 (40%), Gaps = 44/182 (24%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 + S D + LW+ +Q + TGH V + SPD + S + D S KLW+ G Sbjct: 160 TSSGDMSCALWDIETGQQTTS-FTGHTGDVMSLSTSPDFRTFVSGACDASAKLWDVRDGM 218 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARK------------------ 230 F GH +D+ I++ + +GS D+T +++DIRA + Sbjct: 219 CKQTFSGHESDINAITYFPNGHAFATGSDDATCRLFDIRADQEIGMYSHDNIICGITSVA 278 Query: 229 ----------------------LKQD----LPGHADEVYAVDWSPDGEKVVSGGKDRALK 128 LKQ+ L GH + V + + DG V +G D LK Sbjct: 279 FSKSGRLLLGRYDDFNCNVWDVLKQETHGVLAGHDNRVSCLGVTEDGSAVATGSWDSFLK 338 Query: 127 LW 122 +W Sbjct: 339 IW 340 Score = 51.6 bits (122), Expect = 1e-06 Identities = 25/73 (34%), Positives = 38/73 (52%) Frame = -2 Query: 340 RGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEK 161 RGH+A +Y + W++DSR L+S S+D L VWD +P + V ++P G Sbjct: 53 RGHLAKIYAMHWASDSRNLVSASQDGKLIVWDGYTTNKVHAIPLRSSWVMTCAYAPSGNF 112 Query: 160 VVSGGKDRALKLW 122 V GG D ++ Sbjct: 113 VACGGLDNICSIY 125 Score = 44.7 bits (104), Expect = 2e-04 Identities = 29/128 (22%), Positives = 58/128 (45%), Gaps = 4/128 (3%) Frame = -2 Query: 493 ISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQ 314 I + + + GH + ++++ D + L SAS D + +W+G T V A + V Sbjct: 44 IQMRTRRTLRGHLAKIYAMHWASDSRNLVSASQDGKLIVWDGYTTNKVHAIPLRSSWVMT 103 Query: 313 ISWSADSRLLLSGSKDSTLKVWDIRAR----KLKQDLPGHADEVYAVDWSPDGEKVVSGG 146 +++ + G D+ ++ ++ R ++ ++LPGH + + D V S G Sbjct: 104 CAYAPSGNFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFIDDNSIVTSSG 163 Query: 145 KDRALKLW 122 D + LW Sbjct: 164 -DMSCALW 170 Score = 37.0 bits (84), Expect = 0.035 Identities = 27/100 (27%), Positives = 45/100 (45%), Gaps = 3/100 (3%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVV---NHVYFSPDGQWLASASFDKSVKLWNGI 365 +GSDD T L++ I + M H ++ V FS G+ L D + +W+ + Sbjct: 244 TGSDDATCRLFD--IRADQEIGMYSHDNIICGITSVAFSKSGRLLLGRYDDFNCNVWDVL 301 Query: 364 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD 245 + GH V + + D + +GS DS LK+W+ Sbjct: 302 KQETHGVLAGHDNRVSCLGVTEDGSAVATGSWDSFLKIWN 341
>TUP1_YEAST (P16649) Glucose repression regulatory protein TUP1 (Flocculation| suppressor protein) (Repressor AER2) Length = 713 Score = 75.1 bits (183), Expect = 1e-13 Identities = 38/110 (34%), Positives = 64/110 (58%), Gaps = 1/110 (0%) Frame = -2 Query: 448 VNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSK 269 + V FSPDG++LA+ + D+ +++W+ K V +GH D+Y + + L+SGS Sbjct: 446 IRSVCFSPDGKFLATGAEDRLIRIWDIENRKIVMILQGHEQDIYSLDYFPSGDKLVSGSG 505 Query: 268 DSTLKVWDIRARKLKQDLPGHADEVYAVDWSP-DGEKVVSGGKDRALKLW 122 D T+++WD+R + L D V V SP DG+ + +G DRA+++W Sbjct: 506 DRTVRIWDLRTGQCSLTL-SIEDGVTTVAVSPGDGKYIAAGSLDRAVRVW 554 Score = 66.6 bits (161), Expect = 4e-11 Identities = 26/71 (36%), Positives = 48/71 (67%), Gaps = 2/71 (2%) Frame = -2 Query: 328 ADVY--QISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVV 155 +D+Y + +S D + L +G++D +++WDI RK+ L GH ++Y++D+ P G+K+V Sbjct: 442 SDLYIRSVCFSPDGKFLATGAEDRLIRIWDIENRKIVMILQGHEQDIYSLDYFPSGDKLV 501 Query: 154 SGGKDRALKLW 122 SG DR +++W Sbjct: 502 SGSGDRTVRIW 512 Score = 58.2 bits (139), Expect = 1e-08 Identities = 45/153 (29%), Positives = 66/153 (43%), Gaps = 18/153 (11%) Frame = -2 Query: 526 DDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWN-------- 371 D T FL E S+ TGH+ V V F+ DGQ + S S D+SVKLWN Sbjct: 555 DSETGFLVERLDSENESG--TGHKDSVYSVVFTRDGQSVVSGSLDRSVKLWNLQNANNKS 612 Query: 370 ----GITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHA 203 +G + GH V ++ + + +LSGSKD + WD ++ L GH Sbjct: 613 DSKTPNSGTCEVTYIGHKDFVLSVATTQNDEYILSGSKDRGVLFWDKKSGNPLLMLQGHR 672 Query: 202 DEVYAV------DWSPDGEKVVSGGKDRALKLW 122 + V +V P+ +G D ++W Sbjct: 673 NSVISVAVANGSPLGPEYNVFATGSGDCKARIW 705
>GBB1_XENLA (P79959) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 1 (Transducin beta chain 1) (XGbeta1) Length = 340 Score = 74.7 bits (182), Expect = 2e-13 Identities = 37/116 (31%), Positives = 62/116 (53%) Frame = -2 Query: 469 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 290 + GH ++ F D Q + S+ D + LW+ TG+ T F GH DV +S + DSR Sbjct: 139 LAGHTGYLSCCRFLDDNQIITSSG-DTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDSR 197 Query: 289 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 +SG+ D++ K+WD+R +Q GH ++ A+ + P+G +G D +L+ Sbjct: 198 CFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLF 253 Score = 59.3 bits (142), Expect = 7e-09 Identities = 39/140 (27%), Positives = 65/140 (46%), Gaps = 2/140 (1%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SG+ D + LW+ + TGH+ +N + F P+G A+ S D + +L++ + Sbjct: 201 SGACDASAKLWDVR-EGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQ 259 Query: 355 --FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 182 V + + + +++S RLLL+G D VWD L GH + V + Sbjct: 260 ELMVYSHDNIICGITSVAFSKSGRLLLAGYDDFNCNVWDTLKADRAGVLAGHDNRVSCLG 319 Query: 181 WSPDGEKVVSGGKDRALKLW 122 + DG V +G D LK+W Sbjct: 320 VTDDGMAVATGSWDSFLKIW 339 Score = 58.2 bits (139), Expect = 1e-08 Identities = 39/143 (27%), Positives = 68/143 (47%), Gaps = 5/143 (3%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 + S D T LW+ +Q TGH V + +PD + S + D S KLW+ G Sbjct: 159 TSSGDTTCALWDIETGQQTTT-FTGHTGDVMSLSLAPDSRCFVSGACDASAKLWDVREGM 217 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADE-----VY 191 F GH +D+ I + + +GS D+T +++D+RA Q+L ++ + + Sbjct: 218 CRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRA---DQELMVYSHDNIICGIT 274 Query: 190 AVDWSPDGEKVVSGGKDRALKLW 122 +V +S G +++G D +W Sbjct: 275 SVAFSKSGRLLLAGYDDFNCNVW 297 Score = 53.9 bits (128), Expect = 3e-07 Identities = 25/73 (34%), Positives = 37/73 (50%) Frame = -2 Query: 340 RGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEK 161 RGH+A +Y + W DSRLL+S S+D L +WD +P + V ++P G Sbjct: 52 RGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNY 111 Query: 160 VVSGGKDRALKLW 122 V GG D ++ Sbjct: 112 VACGGLDNICPIY 124 Score = 41.2 bits (95), Expect = 0.002 Identities = 33/169 (19%), Positives = 59/169 (34%), Gaps = 45/169 (26%) Frame = -2 Query: 493 ISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAF--------- 341 I + + + GH + +++ D + L SAS D + +W+ T V A Sbjct: 43 IQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMT 102 Query: 340 --------------RGHVADVYQISWS----------------------ADSRLLLSGSK 269 ++ +Y + D +++ S Sbjct: 103 CAYAPSGNYVACGGLDNICPIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIITSSG 162 Query: 268 DSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 D+T +WDI + GH +V ++ +PD VSG D + KLW Sbjct: 163 DTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDSRCFVSGACDASAKLW 211 Score = 36.6 bits (83), Expect = 0.045 Identities = 25/100 (25%), Positives = 45/100 (45%), Gaps = 3/100 (3%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVV---NHVYFSPDGQWLASASFDKSVKLWNGI 365 +GSDD T L++ + + + H ++ V FS G+ L + D + +W+ + Sbjct: 243 TGSDDATCRLFD--LRADQELMVYSHDNIICGITSVAFSKSGRLLLAGYDDFNCNVWDTL 300 Query: 364 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD 245 GH V + + D + +GS DS LK+W+ Sbjct: 301 KADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
>GBB1_HOMAM (O45040) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 1 (Transducin beta chain 1) Length = 340 Score = 74.7 bits (182), Expect = 2e-13 Identities = 39/116 (33%), Positives = 62/116 (53%) Frame = -2 Query: 469 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 290 + GH ++ F D Q + ++S D + LW+ TG+ T F GH DV +S S + R Sbjct: 139 LPGHTGYLSCCRFVDDNQ-IVTSSGDMTCALWDIETGQQCTQFTGHTGDVMSLSLSPNMR 197 Query: 289 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 SG+ D++ K+WDIR +Q PGH ++ AV + P+G +G D +L+ Sbjct: 198 TFTSGACDASAKLWDIRDGMCRQTFPGHESDINAVTFFPNGHAFATGSDDATCRLF 253 Score = 58.5 bits (140), Expect = 1e-08 Identities = 42/143 (29%), Positives = 67/143 (46%), Gaps = 5/143 (3%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMT--GHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 362 SG+ D + LW+ + R T GH+ +N V F P+G A+ S D + +L++ I Sbjct: 201 SGACDASAKLWD---IRDGMCRQTFPGHESDINAVTFFPNGHAFATGSDDATCRLFD-IR 256 Query: 361 GKFVTAFRGH---VADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVY 191 A H + + +++S +LLL+G D VWD + L GH + V Sbjct: 257 ADQELAMYSHDNIICGITSVAFSKSGKLLLAGYDDFNCNVWDSMRTERAGVLAGHDNRVS 316 Query: 190 AVDWSPDGEKVVSGGKDRALKLW 122 + + DG V +G D LK+W Sbjct: 317 CLGVTEDGMAVATGSWDSFLKIW 339 Score = 58.2 bits (139), Expect = 1e-08 Identities = 39/143 (27%), Positives = 71/143 (49%), Gaps = 5/143 (3%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 + S D T LW+ +Q + TGH V + SP+ + S + D S KLW+ G Sbjct: 159 TSSGDMTCALWDIETGQQC-TQFTGHTGDVMSLSLSPNMRTFTSGACDASAKLWDIRDGM 217 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADE-----VY 191 F GH +D+ +++ + +GS D+T +++DIRA Q+L ++ + + Sbjct: 218 CRQTFPGHESDINAVTFFPNGHAFATGSDDATCRLFDIRA---DQELAMYSHDNIICGIT 274 Query: 190 AVDWSPDGEKVVSGGKDRALKLW 122 +V +S G+ +++G D +W Sbjct: 275 SVAFSKSGKLLLAGYDDFNCNVW 297 Score = 52.4 bits (124), Expect = 8e-07 Identities = 25/73 (34%), Positives = 37/73 (50%) Frame = -2 Query: 340 RGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEK 161 RGH+A +Y + W +DSR L+S S+D L VWD +P + V ++P G Sbjct: 52 RGHLAKIYAMHWGSDSRNLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSGSY 111 Query: 160 VVSGGKDRALKLW 122 V GG D ++ Sbjct: 112 VACGGLDNICSIY 124 Score = 41.6 bits (96), Expect = 0.001 Identities = 28/128 (21%), Positives = 56/128 (43%), Gaps = 4/128 (3%) Frame = -2 Query: 493 ISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQ 314 I + + + GH + +++ D + L SAS D + +W+ T V A + V Sbjct: 43 IQMRTRRTLRGHLAKIYAMHWGSDSRNLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMT 102 Query: 313 ISWSADSRLLLSGSKDSTLKVWDIRAR----KLKQDLPGHADEVYAVDWSPDGEKVVSGG 146 +++ + G D+ ++ ++ R ++ ++LPGH + + D + V S G Sbjct: 103 CAYAPSGSYVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFVDDNQIVTSSG 162 Query: 145 KDRALKLW 122 D LW Sbjct: 163 -DMTCALW 169 Score = 39.7 bits (91), Expect = 0.005 Identities = 27/100 (27%), Positives = 46/100 (46%), Gaps = 3/100 (3%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVV---NHVYFSPDGQWLASASFDKSVKLWNGI 365 +GSDD T L++ I + M H ++ V FS G+ L + D + +W+ + Sbjct: 243 TGSDDATCRLFD--IRADQELAMYSHDNIICGITSVAFSKSGKLLLAGYDDFNCNVWDSM 300 Query: 364 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD 245 + GH V + + D + +GS DS LK+W+ Sbjct: 301 RTERAGVLAGHDNRVSCLGVTEDGMAVATGSWDSFLKIWN 340
>FBW1B_HUMAN (Q9UKB1) F-box/WD-repeat protein 11 (F-box/WD-repeat protein 1B)| (F-box and WD-repeats protein beta-TrCP2) Length = 542 Score = 74.7 bits (182), Expect = 2e-13 Identities = 43/138 (31%), Positives = 77/138 (55%), Gaps = 2/138 (1%) Frame = -2 Query: 529 SDDFTMFLWEPTISKQPKAR--MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 S D ++ +W+ + R + GH+ VN V F D +++ SAS D+++K+W+ T + Sbjct: 337 SKDRSIAVWDMASATDITLRRVLVGHRAAVNVVDF--DDKYIVSASGDRTIKVWSTSTCE 394 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 FV GH + + + RL++SGS D+T+++WDI + L GH + V + + Sbjct: 395 FVRTLNGHKRGIACLQYR--DRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRF- 451 Query: 175 PDGEKVVSGGKDRALKLW 122 D +++VSG D +K+W Sbjct: 452 -DNKRIVSGAYDGKIKVW 468 Score = 57.0 bits (136), Expect = 3e-08 Identities = 42/146 (28%), Positives = 76/146 (52%), Gaps = 3/146 (2%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SG D ++ +W+ T + K +TGH V + + D + + + S D +V++W+ TG+ Sbjct: 255 SGLRDNSIKIWDKTSLECLKV-LTGHTGSVLCLQY--DERVIVTGSSDSTVRVWDVNTGE 311 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRAR---KLKQDLPGHADEVYAV 185 + H V + +S + L+++ SKD ++ VWD+ + L++ L GH V V Sbjct: 312 VLNTLIHHNEAVLHLRFS--NGLMVTCSKDRSIAVWDMASATDITLRRVLVGHRAAVNVV 369 Query: 184 DWSPDGEKVVSGGKDRALKLWMN*AC 107 D+ D + +VS DR +K+W C Sbjct: 370 DF--DDKYIVSASGDRTIKVWSTSTC 393 Score = 52.8 bits (125), Expect = 6e-07 Identities = 28/101 (27%), Positives = 55/101 (54%) Frame = -2 Query: 424 DGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD 245 D + + S D S+K+W+ + + + GH V + + D R++++GS DST++VWD Sbjct: 249 DDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSVLCLQY--DERVIVTGSSDSTVRVWD 306 Query: 244 IRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 + ++ L H + V + +S +V+ KDR++ +W Sbjct: 307 VNTGEVLNTLIHHNEAVLHLRFS--NGLMVTCSKDRSIAVW 345
>PRP46_ASPFU (Q4WT34) Pre-mRNA-splicing factor prp46 (Pre-mRNA-processing| protein 46) Length = 453 Score = 74.7 bits (182), Expect = 2e-13 Identities = 41/138 (29%), Positives = 67/138 (48%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SG+ D T+ +W + +TGH V + SP +L S DK VK W+ T K Sbjct: 161 SGAGDRTIKIWNLATGAL-RLTLTGHISTVRGLAVSPRHPYLFSCGEDKMVKCWDLETNK 219 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 + + GH++ VY ++ LL++G +D +VWD+R R L GH V + Sbjct: 220 VIRHYHGHLSGVYTLALHPRLDLLVTGGRDGVARVWDMRTRSNIHVLSGHKGTVADLKCQ 279 Query: 175 PDGEKVVSGGKDRALKLW 122 ++++G D ++LW Sbjct: 280 EADPQIITGSLDATVRLW 297 Score = 73.2 bits (178), Expect = 4e-13 Identities = 34/116 (29%), Positives = 60/116 (51%) Frame = -2 Query: 469 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 290 ++GH V + P+ +W AS + D+++K+WN TG GH++ V ++ S Sbjct: 140 ISGHLGWVRSLAVEPNNEWFASGAGDRTIKIWNLATGALRLTLTGHISTVRGLAVSPRHP 199 Query: 289 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 L S +D +K WD+ K+ + GH VY + P + +V+GG+D ++W Sbjct: 200 YLFSCGEDKMVKCWDLETNKVIRHYHGHLSGVYTLALHPRLDLLVTGGRDGVARVW 255 Score = 52.4 bits (124), Expect = 8e-07 Identities = 40/146 (27%), Positives = 70/146 (47%), Gaps = 8/146 (5%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 +GS D T+ LW+ K +T H+K V ++ P ASAS S+K W G Sbjct: 287 TGSLDATVRLWDLAAGKTMGV-LTHHKKGVRNLAIHPREFTFASASTG-SIKQWKCPEGD 344 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDL-----PGHADE-- 197 F+ F GH A + ++ + D+ +L SG + ++ WD + Q + PG D Sbjct: 345 FMQNFEGHNAVINSLAVNEDN-VLFSGGDNGSMCFWDWKTGYKFQSIDTMAQPGSLDAEA 403 Query: 196 -VYAVDWSPDGEKVVSGGKDRALKLW 122 + + + G ++++G D+ +K+W Sbjct: 404 GIMSATFDRTGLRLITGEADKTIKVW 429 Score = 45.1 bits (105), Expect = 1e-04 Identities = 22/79 (27%), Positives = 39/79 (49%) Frame = -2 Query: 358 KFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDW 179 K + GH+ V ++ ++ SG+ D T+K+W++ L+ L GH V + Sbjct: 135 KLMRVISGHLGWVRSLAVEPNNEWFASGAGDRTIKIWNLATGALRLTLTGHISTVRGLAV 194 Query: 178 SPDGEKVVSGGKDRALKLW 122 SP + S G+D+ +K W Sbjct: 195 SPRHPYLFSCGEDKMVKCW 213 Score = 32.0 bits (71), Expect = 1.1 Identities = 25/116 (21%), Positives = 47/116 (40%) Frame = -2 Query: 469 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 290 ++GH+ V + + + S D +V+LW+ GK + H V ++ Sbjct: 266 LSGHKGTVADLKCQEADPQIITGSLDATVRLWDLAAGKTMGVLTHHKKGVRNLAIHPREF 325 Query: 289 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 S S S +K W Q+ GH + ++ + D + SGG + ++ W Sbjct: 326 TFASASTGS-IKQWKCPEGDFMQNFEGHNAVINSLAVNED-NVLFSGGDNGSMCFW 379
>TB1RB_XENLA (Q6GPC6) F-box-like/WD-repeat-containing protein TBL1XR1-B| (Transducin beta-like 1X-related homolog 1-B) (Nuclear receptor corepressor/HDAC3 complex subunit TBLR1-B) (TBL1-related protein 1-B) Length = 522 Score = 74.7 bits (182), Expect = 2e-13 Identities = 41/130 (31%), Positives = 64/130 (49%), Gaps = 9/130 (6%) Frame = -2 Query: 484 QPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISW 305 +P GH VN + + P G LAS S D ++K+W+ V + H ++Y I W Sbjct: 348 RPIKTFQGHTNEVNAIKWDPTGNLLASCSDDMTLKIWSMKHDTCVHDLQAHNKEIYTIKW 407 Query: 304 SAD---------SRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVS 152 S + +L S S DST+++WD+ L H + VY+V +SPDG + S Sbjct: 408 SPTGPGTNNPNANLMLASASFDSTVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLAS 467 Query: 151 GGKDRALKLW 122 G D+ + +W Sbjct: 468 GSFDKCVHIW 477 Score = 64.3 bits (155), Expect = 2e-10 Identities = 37/99 (37%), Positives = 57/99 (57%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 S S D T+ LW+ +T HQ+ V V FSPDG++LAS SFDK V +WN TG Sbjct: 425 SASFDSTVRLWDVDRGICIHT-LTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWNTQTGA 483 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIR 239 V ++RG ++++ W+A + + + D ++ V D+R Sbjct: 484 LVHSYRG-TGGIFEVCWNAAGDKVGASASDGSVCVLDLR 521 Score = 62.8 bits (151), Expect = 6e-10 Identities = 42/141 (29%), Positives = 64/141 (45%), Gaps = 9/141 (6%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQ---------WLASASFDKSV 383 S SDD T+ +W + H K + + +SP G LASASFD +V Sbjct: 374 SCSDDMTLKIWSMKHDTCVHD-LQAHNKEIYTIKWSPTGPGTNNPNANLMLASASFDSTV 432 Query: 382 KLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHA 203 +LW+ G + H VY +++S D R L SGS D + +W+ + L G Sbjct: 433 RLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWNTQTGALVHSYRG-T 491 Query: 202 DEVYAVDWSPDGEKVVSGGKD 140 ++ V W+ G+KV + D Sbjct: 492 GGIFEVCWNAAGDKVGASASD 512 Score = 58.5 bits (140), Expect = 1e-08 Identities = 32/105 (30%), Positives = 46/105 (43%), Gaps = 9/105 (8%) Frame = -2 Query: 409 ASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARK 230 AS S D + + + + F+GH +V I W LL S S D TLK+W ++ Sbjct: 331 ASCSTDMCIHVCKLGQDRPIKTFQGHTNEVNAIKWDPTGNLLASCSDDMTLKIWSMKHDT 390 Query: 229 LKQDLPGHADEVYAVDWSPDGE---------KVVSGGKDRALKLW 122 DL H E+Y + WSP G + S D ++LW Sbjct: 391 CVHDLQAHNKEIYTIKWSPTGPGTNNPNANLMLASASFDSTVRLW 435 Score = 56.2 bits (134), Expect = 6e-08 Identities = 30/113 (26%), Positives = 53/113 (46%) Frame = -2 Query: 460 HQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLL 281 H+ + + ++ G ++ SA DK+ +W+ TG+ F H A + W +++ Sbjct: 273 HKGPIFALKWNKKGNFILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQSNN-TFA 331 Query: 280 SGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 S S D + V + + + GH +EV A+ W P G + S D LK+W Sbjct: 332 SCSTDMCIHVCKLGQDRPIKTFQGHTNEVNAIKWDPTGNLLASCSDDMTLKIW 384 Score = 52.8 bits (125), Expect = 6e-07 Identities = 32/130 (24%), Positives = 57/130 (43%), Gaps = 14/130 (10%) Frame = -2 Query: 469 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLW----NGITGKFVTAFRGHV--------- 329 + GH+ V ++P LAS S D + ++W N +G R + Sbjct: 173 LRGHESEVFICAWNPVSDLLASGSGDSTARIWNLSENSTSGSTQLVLRHCIREGGQDVPS 232 Query: 328 -ADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVS 152 DV + W+++ LL +GS D ++W + L L H ++A+ W+ G ++S Sbjct: 233 NKDVTSLDWNSEGTLLATGSYDGFARIW-TKDGNLASTLGQHKGPIFALKWNKKGNFILS 291 Query: 151 GGKDRALKLW 122 G D+ +W Sbjct: 292 AGVDKTTIIW 301
>MORG1_XENLA (Q3KQ62) Mitogen-activated protein kinase organizer 1 (MAPK| organizer 1) Length = 314 Score = 74.7 bits (182), Expect = 2e-13 Identities = 36/126 (28%), Positives = 67/126 (53%) Frame = -2 Query: 499 PTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADV 320 P + ++ + ++ +Q V V F+ DG + + DKS+KLWN G + + GH +V Sbjct: 11 PELPQKLQHKLECNQGAVRAVRFNVDGNYCMTCGSDKSLKLWNPHKGSLLKTYSGHGYEV 70 Query: 319 YQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKD 140 + S D+ L S S D T+ +WD+ ++ + GHA +V V ++ + ++SG D Sbjct: 71 LDTAGSCDNSQLCSCSSDKTVILWDVAQGQVVRKFRGHAGKVNCVQFNEEATVIISGSID 130 Query: 139 RALKLW 122 +++ W Sbjct: 131 SSIRCW 136 Score = 61.6 bits (148), Expect = 1e-09 Identities = 38/119 (31%), Positives = 60/119 (50%) Frame = -2 Query: 523 DFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTA 344 D ++ LW P K +GH V S D L S S DK+V LW+ G+ V Sbjct: 46 DKSLKLWNPHKGSLLKT-YSGHGYEVLDTAGSCDNSQLCSCSSDKTVILWDVAQGQVVRK 104 Query: 343 FRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDG 167 FRGH V + ++ ++ +++SGS DS+++ WD R+R+ D + +D + DG Sbjct: 105 FRGHAGKVNCVQFNEEATVIISGSIDSSIRCWDCRSRR--------PDAIQIMDEAKDG 155 Score = 44.3 bits (103), Expect = 2e-04 Identities = 46/180 (25%), Positives = 72/180 (40%), Gaps = 42/180 (23%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWN----- 371 S S D T+ LW+ Q + GH VN V F+ + + S S D S++ W+ Sbjct: 84 SCSSDKTVILWD-VAQGQVVRKFRGHAGKVNCVQFNEEATVIISGSIDSSIRCWDCRSRR 142 Query: 370 ------------GITGKFVTAF-----------------RGHVADVYQ------ISWSAD 296 GI+ V+A +G + Y +S+S D Sbjct: 143 PDAIQIMDEAKDGISSVKVSAHEILAGSVDGNLRRYDLRKGEMCADYLGSPITCVSFSQD 202 Query: 295 SRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD--WSPDGEKVVSGGKDRALKLW 122 S+ LL+ S DSTL++ D +L + GH + Y +D S V+S +D + W Sbjct: 203 SQCLLASSLDSTLRLLDKDTGELLGEYTGHQNLSYKLDSCLSEKDTHVLSCSEDGTVCFW 262
>TB1RA_XENLA (Q7SZM9) F-box-like/WD-repeat-containing protein TBL1XR1-A| (Transducin beta-like 1X-related protein 1-A) (Nuclear receptor corepressor/HDAC3 complex subunit TBLR1-A) (TBL1-related protein 1-A) (xTBLR1) Length = 519 Score = 74.7 bits (182), Expect = 2e-13 Identities = 41/130 (31%), Positives = 64/130 (49%), Gaps = 9/130 (6%) Frame = -2 Query: 484 QPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISW 305 +P GH VN + + P G LAS S D ++K+W+ V + H ++Y I W Sbjct: 345 RPIKTFQGHTNEVNAIKWDPTGNLLASCSDDMTLKIWSMKHDTCVHDLQAHNKEIYTIKW 404 Query: 304 SAD---------SRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVS 152 S + +L S S DST+++WD+ L H + VY+V +SPDG + S Sbjct: 405 SPTGPGTNNPNANLMLASASFDSTVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLAS 464 Query: 151 GGKDRALKLW 122 G D+ + +W Sbjct: 465 GSFDKCVHIW 474 Score = 64.3 bits (155), Expect = 2e-10 Identities = 37/99 (37%), Positives = 57/99 (57%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 S S D T+ LW+ +T HQ+ V V FSPDG++LAS SFDK V +WN TG Sbjct: 422 SASFDSTVRLWDVDRGICIHT-LTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWNTQTGA 480 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIR 239 V ++RG ++++ W+A + + + D ++ V D+R Sbjct: 481 LVHSYRG-TGGIFEVCWNAAGDKVGASASDGSVCVLDLR 518 Score = 62.8 bits (151), Expect = 6e-10 Identities = 42/141 (29%), Positives = 64/141 (45%), Gaps = 9/141 (6%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQ---------WLASASFDKSV 383 S SDD T+ +W + H K + + +SP G LASASFD +V Sbjct: 371 SCSDDMTLKIWSMKHDTCVHD-LQAHNKEIYTIKWSPTGPGTNNPNANLMLASASFDSTV 429 Query: 382 KLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHA 203 +LW+ G + H VY +++S D R L SGS D + +W+ + L G Sbjct: 430 RLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWNTQTGALVHSYRG-T 488 Query: 202 DEVYAVDWSPDGEKVVSGGKD 140 ++ V W+ G+KV + D Sbjct: 489 GGIFEVCWNAAGDKVGASASD 509 Score = 58.5 bits (140), Expect = 1e-08 Identities = 32/105 (30%), Positives = 46/105 (43%), Gaps = 9/105 (8%) Frame = -2 Query: 409 ASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARK 230 AS S D + + + + F+GH +V I W LL S S D TLK+W ++ Sbjct: 328 ASCSTDMCIHVCKLGQDRPIKTFQGHTNEVNAIKWDPTGNLLASCSDDMTLKIWSMKHDT 387 Query: 229 LKQDLPGHADEVYAVDWSPDGE---------KVVSGGKDRALKLW 122 DL H E+Y + WSP G + S D ++LW Sbjct: 388 CVHDLQAHNKEIYTIKWSPTGPGTNNPNANLMLASASFDSTVRLW 432 Score = 56.2 bits (134), Expect = 6e-08 Identities = 30/113 (26%), Positives = 53/113 (46%) Frame = -2 Query: 460 HQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLL 281 H+ + + ++ G ++ SA DK+ +W+ TG+ F H A + W +++ Sbjct: 270 HKGPIFALKWNKKGNFILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQSNN-TFA 328 Query: 280 SGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 S S D + V + + + GH +EV A+ W P G + S D LK+W Sbjct: 329 SCSTDMCIHVCKLGQDRPIKTFQGHTNEVNAIKWDPTGNLLASCSDDMTLKIW 381 Score = 52.8 bits (125), Expect = 6e-07 Identities = 32/130 (24%), Positives = 57/130 (43%), Gaps = 14/130 (10%) Frame = -2 Query: 469 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLW----NGITGKFVTAFRGHV--------- 329 + GH+ V ++P LAS S D + ++W N +G R + Sbjct: 170 LRGHESEVFICAWNPVSDLLASGSGDSTARIWNLSENSTSGSTQLVLRHCIREGGQDVPS 229 Query: 328 -ADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVS 152 DV + W+++ LL +GS D ++W + L L H ++A+ W+ G ++S Sbjct: 230 NKDVTSLDWNSEGTLLATGSYDGFARIW-TKDGNLASTLGQHKGPIFALKWNKKGNFILS 288 Query: 151 GGKDRALKLW 122 G D+ +W Sbjct: 289 AGVDKTTIIW 298
>APAF_HUMAN (O14727) Apoptotic protease-activating factor 1 (Apaf-1)| Length = 1248 Score = 74.3 bits (181), Expect = 2e-13 Identities = 40/115 (34%), Positives = 62/115 (53%), Gaps = 2/115 (1%) Frame = -2 Query: 460 HQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR--L 287 H+ V FS D +++A+ S DK VK+WN +TG+ V + H V ++ S L Sbjct: 656 HEDEVLCCAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLL 715 Query: 286 LLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 L +GS D LK+WD+ ++ + + GH + V +SPD + + S D LKLW Sbjct: 716 LATGSSDCFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLW 770 Score = 63.5 bits (153), Expect = 3e-10 Identities = 40/113 (35%), Positives = 57/113 (50%) Frame = -2 Query: 460 HQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLL 281 H+K V H+ F+ D + L S+S D +++WN K + RGH V +SR LL Sbjct: 1002 HKKTVWHIQFTADEKTLISSSDDAEIQVWNWQLDKCI-FLRGHQETVKDFRLLKNSR-LL 1059 Query: 280 SGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 S S D T+KVW+I ++D H V + D S D K S D+ K+W Sbjct: 1060 SWSFDGTVKVWNIITGNKEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIW 1112 Score = 58.9 bits (141), Expect = 9e-09 Identities = 47/193 (24%), Positives = 75/193 (38%), Gaps = 55/193 (28%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITG- 359 +GS D + LW+ K+ + M GH VNH FSPD + LAS S D ++KLW+ + Sbjct: 718 TGSSDCFLKLWDLN-QKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSAN 776 Query: 358 --------KFVTAFRGHVADVYQI----SWSADSRLLLSGSKDS---------------- 263 +F D+ I SWSAD ++ +K+ Sbjct: 777 ERKSINVKQFFLNLEDPQEDMEVIVKCCSWSADGARIMVAAKNKIFLFDIHTSGLLGEIH 836 Query: 262 --------------------------TLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEK 161 +++W+ +R D GH V+ V +SPDG Sbjct: 837 TGHHSTIQYCDFSPQNHLAVVALSQYCVELWNTDSRSKVADCRGHLSWVHGVMFSPDGSS 896 Query: 160 VVSGGKDRALKLW 122 ++ D+ ++LW Sbjct: 897 FLTSSDDQTIRLW 909 Score = 55.8 bits (133), Expect = 7e-08 Identities = 42/138 (30%), Positives = 60/138 (43%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 S SDD + +W + K R GHQ+ V + + L S SFD +VK+WN ITG Sbjct: 1020 SSSDDAEIQVWNWQLDKCIFLR--GHQETVKDFRLLKNSR-LLSWSFDGTVKVWNIITGN 1076 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 F H V S D+ S S D T K+W +L GH V +S Sbjct: 1077 KEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHELRGHNGCVRCSAFS 1136 Query: 175 PDGEKVVSGGKDRALKLW 122 D + +G + +++W Sbjct: 1137 VDSTLLATGDDNGEIRIW 1154 Score = 48.5 bits (114), Expect = 1e-05 Identities = 37/138 (26%), Positives = 63/138 (45%), Gaps = 8/138 (5%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 S S D T+ +W I+ + HQ V S D +S S DK+ K+W+ Sbjct: 1060 SWSFDGTVKVWN-IITGNKEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLLL 1118 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKL--------KQDLPGHAD 200 + RGH V ++S DS LL +G + +++W++ +L ++ H Sbjct: 1119 PLHELRGHNGCVRCSAFSVDSTLLATGDDNGEIRIWNVSNGELLHLCAPLSEEGAATHGG 1178 Query: 199 EVYAVDWSPDGEKVVSGG 146 V + +SPDG+ ++S G Sbjct: 1179 WVTDLCFSPDGKMLISAG 1196 Score = 48.5 bits (114), Expect = 1e-05 Identities = 23/76 (30%), Positives = 38/76 (50%) Frame = -2 Query: 466 TGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRL 287 TGH + + FSP A V+LWN + V RGH++ V+ + +S D Sbjct: 837 TGHHSTIQYCDFSPQNHLAVVALSQYCVELWNTDSRSKVADCRGHLSWVHGVMFSPDGSS 896 Query: 286 LLSGSKDSTLKVWDIR 239 L+ S D T+++W+ + Sbjct: 897 FLTSSDDQTIRLWETK 912 Score = 39.3 bits (90), Expect = 0.007 Identities = 20/73 (27%), Positives = 34/73 (46%) Frame = -2 Query: 340 RGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEK 161 R H VY +S D + + S D TL+V+ + ++ H DEV +S D Sbjct: 612 RPHTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRF 671 Query: 160 VVSGGKDRALKLW 122 + + D+ +K+W Sbjct: 672 IATCSVDKKVKIW 684
>TUP1_KLULA (P56094) Transcriptional repressor TUP1| Length = 682 Score = 74.3 bits (181), Expect = 2e-13 Identities = 46/158 (29%), Positives = 71/158 (44%), Gaps = 49/158 (31%) Frame = -2 Query: 448 VNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSK 269 + V FSPDG++LA+ + DK +++W+ T K V +GH D+Y + + L+SGS Sbjct: 409 IRSVCFSPDGKFLATGAEDKLIRIWDLETKKIVMTLKGHEQDIYSLDYFPSGNKLVSGSG 468 Query: 268 DSTLKVWD----------------------------IRARKLKQDL-------------- 215 D T+++WD I A L + + Sbjct: 469 DRTVRIWDLTTGTCSLTLSIEDGVTTVAVSPGEGKFIAAGSLDRTVRVWDSDTGFLVERL 528 Query: 214 -------PGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 GH D VY+V ++ DG+ VVSG DR++KLW Sbjct: 529 DSENELGTGHRDSVYSVVFTRDGKGVVSGSLDRSVKLW 566 Score = 66.2 bits (160), Expect = 5e-11 Identities = 27/83 (32%), Positives = 51/83 (61%), Gaps = 2/83 (2%) Frame = -2 Query: 364 TGKFVTAFRGHVADVY--QISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVY 191 TG +A +D+Y + +S D + L +G++D +++WD+ +K+ L GH ++Y Sbjct: 393 TGNQNSAASTASSDLYIRSVCFSPDGKFLATGAEDKLIRIWDLETKKIVMTLKGHEQDIY 452 Query: 190 AVDWSPDGEKVVSGGKDRALKLW 122 ++D+ P G K+VSG DR +++W Sbjct: 453 SLDYFPSGNKLVSGSGDRTVRIW 475 Score = 60.8 bits (146), Expect = 2e-09 Identities = 40/128 (31%), Positives = 63/128 (49%), Gaps = 13/128 (10%) Frame = -2 Query: 466 TGHQKVVNHVYFSPDGQWLASASFDKSVKLW--NGITGKFVTA-----FRGHVADVYQIS 308 TGH+ V V F+ DG+ + S S D+SVKLW NG++G+ A + GH V ++ Sbjct: 536 TGHRDSVYSVVFTRDGKGVVSGSLDRSVKLWNLNGLSGQKSHAECEVTYTGHKDFVLSVA 595 Query: 307 WSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAV------DWSPDGEKVVSGG 146 + + +LSGSKD + WD ++ L GH + V +V P+ +G Sbjct: 596 TTQNDEYILSGSKDRGVLFWDTKSGNPLLMLQGHRNSVISVTVANGHPLGPEYGVFATGS 655 Query: 145 KDRALKLW 122 D ++W Sbjct: 656 GDCKARIW 663
>WSB2_MOUSE (O54929) WD repeat and SOCS box-containing protein 2 (WSB-2) (SOCS| box-containing WD protein SWiP-2) Length = 404 Score = 73.9 bits (180), Expect = 3e-13 Identities = 44/140 (31%), Positives = 75/140 (53%), Gaps = 2/140 (1%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQW-LASASFDKSVKLWN-GIT 362 +G +D + +WE ++GHQ VV + F+P G L SAS DK++++W+ Sbjct: 128 TGLNDGQIKIWEVQTGLL-LLNLSGHQDVVRDLSFTPSGSLILVSASRDKTLRIWDLNKH 186 Query: 361 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 182 GK + GH+ VY S S D +L S + + ++ +W +R+ L + L GH V + D Sbjct: 187 GKQIQVLSGHLQWVYCCSISPDCSMLCSAAGEKSVFLWSMRSYTLIRKLEGHQSSVVSCD 246 Query: 181 WSPDGEKVVSGGKDRALKLW 122 +SPD +V+ D ++ +W Sbjct: 247 FSPDSALLVTASYDTSVIMW 266 Score = 64.3 bits (155), Expect = 2e-10 Identities = 44/150 (29%), Positives = 72/150 (48%), Gaps = 12/150 (8%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 S S D T+ +W+ + ++GH + V SPD L SA+ +KSV LW+ + Sbjct: 171 SASRDKTLRIWDLNKHGKQIQVLSGHLQWVYCCSISPDCSMLCSAAGEKSVFLWSMRSYT 230 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD----IRARKL--------KQDLP 212 + GH + V +S DS LL++ S D+++ +WD R R L D Sbjct: 231 LIRKLEGHQSSVVSCDFSPDSALLVTASYDTSVIMWDPYTGARLRSLHHTQLEPTMDDSD 290 Query: 211 GHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 H + +V +SP+G + + DR L++W Sbjct: 291 VHMSSLRSVCFSPEGLYLATVADDRLLRIW 320 Score = 56.2 bits (134), Expect = 6e-08 Identities = 33/99 (33%), Positives = 52/99 (52%), Gaps = 2/99 (2%) Frame = -2 Query: 412 LASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWS-ADSRLLLSGSKDSTLKVWDIRA 236 LA+ D +K+W TG + GH V +S++ + S +L+S S+D TL++WD+ Sbjct: 126 LATGLNDGQIKIWEVQTGLLLLNLSGHQDVVRDLSFTPSGSLILVSASRDKTLRIWDLNK 185 Query: 235 R-KLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 K Q L GH VY SPD + S ++++ LW Sbjct: 186 HGKQIQVLSGHLQWVYCCSISPDCSMLCSAAGEKSVFLW 224 Score = 43.5 bits (101), Expect = 4e-04 Identities = 18/57 (31%), Positives = 34/57 (59%), Gaps = 1/57 (1%) Frame = -2 Query: 289 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKV-VSGGKDRALKLW 122 +L +G D +K+W+++ L +L GH D V + ++P G + VS +D+ L++W Sbjct: 125 ILATGLNDGQIKIWEVQTGLLLLNLSGHQDVVRDLSFTPSGSLILVSASRDKTLRIW 181
>RBBP4_BRARE (Q6P3H7) Histone-binding protein RBBP4 (Retinoblastoma-binding| protein 4) (RBBP-4) Length = 423 Score = 73.9 bits (180), Expect = 3e-13 Identities = 53/151 (35%), Positives = 78/151 (51%), Gaps = 13/151 (8%) Frame = -2 Query: 535 SGSDDFTMFLWE-PTISKQ-----PKARMTGHQKVVNHVYFSPDGQWL-ASASFDKSVKL 377 S SDD T+ LW+ T+ K+ K TGH VV V + + L S + D+ + + Sbjct: 194 SASDDHTICLWDISTVPKEGKIVDAKTIFTGHTAVVEDVSWHLLHESLFGSVADDQKLMI 253 Query: 376 WN---GITGKFVTAFRGHVADVYQISWSADSRLLLS-GSKDSTLKVWDIRARKLK-QDLP 212 W+ T K A H A+V +S++ S +L+ GS D T+ +WD+R KLK Sbjct: 254 WDTRSNNTSKPSHAVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFE 313 Query: 211 GHADEVYAVDWSPDGEKVV-SGGKDRALKLW 122 H DE++ V WSP E ++ S G DR L +W Sbjct: 314 SHKDEIFQVQWSPHNETILASSGTDRRLNVW 344 Score = 36.2 bits (82), Expect = 0.059 Identities = 27/82 (32%), Positives = 37/82 (45%), Gaps = 9/82 (10%) Frame = -2 Query: 340 RGHVADVYQISWSADSR-LLLSGSKDSTLKVWDI-------RARKLKQDLPGHADEVYAV 185 RGH + Y +SW+ + R LLS S D T+ +WDI + K GH V V Sbjct: 173 RGHQKEGYGLSWNPNLRSCLLSASDDHTICLWDISTVPKEGKIVDAKTIFTGHTAVVEDV 232 Query: 184 DWSPDGEKVV-SGGKDRALKLW 122 W E + S D+ L +W Sbjct: 233 SWHLLHESLFGSVADDQKLMIW 254
>GBB4_RAT (O35353) Guanine nucleotide-binding protein beta subunit 4| (Transducin beta chain 4) Length = 339 Score = 73.9 bits (180), Expect = 3e-13 Identities = 39/116 (33%), Positives = 61/116 (52%) Frame = -2 Query: 469 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 290 + GH ++ F DGQ + S+ D + LW+ TG+ T F GH DV +S S D + Sbjct: 138 LPGHTGYLSCCRFLDDGQIITSSG-DTTCALWDIETGQQTTTFTGHSGDVMSLSLSPDLK 196 Query: 289 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 +SG+ D++ K+WDIR +Q GH ++ AV + P G +G D +L+ Sbjct: 197 TFVSGACDASSKLWDIRDGMCRQSFTGHISDINAVSFFPSGYAFATGSDDATCRLF 252 Score = 58.9 bits (141), Expect = 9e-09 Identities = 40/143 (27%), Positives = 70/143 (48%), Gaps = 5/143 (3%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 + S D T LW+ +Q TGH V + SPD + S + D S KLW+ G Sbjct: 158 TSSGDTTCALWDIETGQQTTT-FTGHSGDVMSLSLSPDLKTFVSGACDASSKLWDIRDGM 216 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADE-----VY 191 +F GH++D+ +S+ +GS D+T +++D+RA Q+L ++ + + Sbjct: 217 CRQSFTGHISDINAVSFFPSGYAFATGSDDATCRLFDLRA---DQELLLYSHDNIICGIT 273 Query: 190 AVDWSPDGEKVVSGGKDRALKLW 122 +V +S G +++G D +W Sbjct: 274 SVAFSKSGRLLLAGYDDFNCSVW 296 Score = 53.9 bits (128), Expect = 3e-07 Identities = 25/73 (34%), Positives = 37/73 (50%) Frame = -2 Query: 340 RGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEK 161 RGH+A +Y + W DSRLL+S S+D L +WD +P + V ++P G Sbjct: 51 RGHLAKIYAMHWGYDSRLLVSASQDGKLIIWDSYTTNKMHAIPLRSSWVMTCAYAPSGNY 110 Query: 160 VVSGGKDRALKLW 122 V GG D ++ Sbjct: 111 VACGGLDNICSIY 123 Score = 43.5 bits (101), Expect = 4e-04 Identities = 27/128 (21%), Positives = 58/128 (45%), Gaps = 4/128 (3%) Frame = -2 Query: 493 ISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQ 314 I + + + GH + +++ D + L SAS D + +W+ T + A + V Sbjct: 42 IQMRTRRTLRGHLAKIYAMHWGYDSRLLVSASQDGKLIIWDSYTTNKMHAIPLRSSWVMT 101 Query: 313 ISWSADSRLLLSGSKDSTLKVWDIRAR----KLKQDLPGHADEVYAVDWSPDGEKVVSGG 146 +++ + G D+ +++++ R ++ ++LPGH + + DG+ + S G Sbjct: 102 CAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELPGHTGYLSCCRFLDDGQIITSSG 161 Query: 145 KDRALKLW 122 D LW Sbjct: 162 -DTTCALW 168 Score = 38.1 bits (87), Expect = 0.016 Identities = 25/100 (25%), Positives = 46/100 (46%), Gaps = 3/100 (3%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVV---NHVYFSPDGQWLASASFDKSVKLWNGI 365 +GSDD T L++ + + + H ++ V FS G+ L + D + +W+ + Sbjct: 242 TGSDDATCRLFD--LRADQELLLYSHDNIICGITSVAFSKSGRLLLAGYDDFNCSVWDAL 299 Query: 364 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD 245 G GH V + + D + +GS DS L++W+ Sbjct: 300 KGGRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLRIWN 339
>GBB4_MOUSE (P29387) Guanine nucleotide-binding protein beta subunit 4| (Transducin beta chain 4) Length = 339 Score = 73.9 bits (180), Expect = 3e-13 Identities = 39/116 (33%), Positives = 61/116 (52%) Frame = -2 Query: 469 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 290 + GH ++ F DGQ + S+ D + LW+ TG+ T F GH DV +S S D + Sbjct: 138 LPGHTGYLSCCRFLDDGQIITSSG-DTTCALWDIETGQQTTTFTGHSGDVMSLSLSPDLK 196 Query: 289 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 +SG+ D++ K+WDIR +Q GH ++ AV + P G +G D +L+ Sbjct: 197 TFVSGACDASSKLWDIRDGMCRQSFTGHISDINAVSFFPSGYAFATGSDDATCRLF 252 Score = 58.9 bits (141), Expect = 9e-09 Identities = 40/143 (27%), Positives = 70/143 (48%), Gaps = 5/143 (3%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 + S D T LW+ +Q TGH V + SPD + S + D S KLW+ G Sbjct: 158 TSSGDTTCALWDIETGQQTTT-FTGHSGDVMSLSLSPDLKTFVSGACDASSKLWDIRDGM 216 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADE-----VY 191 +F GH++D+ +S+ +GS D+T +++D+RA Q+L ++ + + Sbjct: 217 CRQSFTGHISDINAVSFFPSGYAFATGSDDATCRLFDLRA---DQELLLYSHDNIICGIT 273 Query: 190 AVDWSPDGEKVVSGGKDRALKLW 122 +V +S G +++G D +W Sbjct: 274 SVAFSKSGRLLLAGYDDFNCSVW 296 Score = 53.9 bits (128), Expect = 3e-07 Identities = 25/73 (34%), Positives = 37/73 (50%) Frame = -2 Query: 340 RGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEK 161 RGH+A +Y + W DSRLL+S S+D L +WD +P + V ++P G Sbjct: 51 RGHLAKIYAMHWGYDSRLLVSASQDGKLIIWDSYTTNKMHAIPLRSSWVMTCAYAPSGNY 110 Query: 160 VVSGGKDRALKLW 122 V GG D ++ Sbjct: 111 VACGGLDNICSIY 123 Score = 43.5 bits (101), Expect = 4e-04 Identities = 27/128 (21%), Positives = 58/128 (45%), Gaps = 4/128 (3%) Frame = -2 Query: 493 ISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQ 314 I + + + GH + +++ D + L SAS D + +W+ T + A + V Sbjct: 42 IQMRTRRTLRGHLAKIYAMHWGYDSRLLVSASQDGKLIIWDSYTTNKMHAIPLRSSWVMT 101 Query: 313 ISWSADSRLLLSGSKDSTLKVWDIRAR----KLKQDLPGHADEVYAVDWSPDGEKVVSGG 146 +++ + G D+ +++++ R ++ ++LPGH + + DG+ + S G Sbjct: 102 CAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELPGHTGYLSCCRFLDDGQIITSSG 161 Query: 145 KDRALKLW 122 D LW Sbjct: 162 -DTTCALW 168 Score = 37.4 bits (85), Expect = 0.027 Identities = 25/100 (25%), Positives = 46/100 (46%), Gaps = 3/100 (3%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVV---NHVYFSPDGQWLASASFDKSVKLWNGI 365 +GSDD T L++ + + + H ++ V FS G+ L + D + +W+ + Sbjct: 242 TGSDDATCRLFD--LRADQELLLYSHDNIICGITSVAFSKSGRLLLAGYDDFNCSVWDAL 299 Query: 364 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD 245 G GH V + + D + +GS DS L++W+ Sbjct: 300 KGGRSGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLRIWN 339
>PRL2_ARATH (Q39190) PP1/PP2A phosphatases pleiotropic regulator PRL2| Length = 479 Score = 73.6 bits (179), Expect = 3e-13 Identities = 33/116 (28%), Positives = 56/116 (48%) Frame = -2 Query: 469 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 290 + GH V V F P +W + S D+++K+W+ TG GH+ V ++ S Sbjct: 166 LQGHLGWVRSVAFDPSNEWFCTGSADRTIKIWDVATGVLKLTLTGHIGQVRGLAVSNRHT 225 Query: 289 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 + S D +K WD+ K+ + GH VY + P + V++GG+D ++W Sbjct: 226 YMFSAGDDKQVKCWDLEQNKVIRSYHGHLHGVYCLALHPTLDVVLTGGRDSVCRVW 281 Score = 72.8 bits (177), Expect = 6e-13 Identities = 43/138 (31%), Positives = 71/138 (51%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 +GS D T+ +W+ K +TGH V + S ++ SA DK VK W+ K Sbjct: 187 TGSADRTIKIWDVATGVL-KLTLTGHIGQVRGLAVSNRHTYMFSAGDDKQVKCWDLEQNK 245 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 + ++ GH+ VY ++ ++L+G +DS +VWDIR + LP H +V++V Sbjct: 246 VIRSYHGHLHGVYCLALHPTLDVVLTGGRDSVCRVWDIRTKMQIFVLP-HDSDVFSVLAR 304 Query: 175 PDGEKVVSGGKDRALKLW 122 P +V++G D +K W Sbjct: 305 PTDPQVITGSHDSTIKFW 322 Score = 39.7 bits (91), Expect = 0.005 Identities = 36/148 (24%), Positives = 63/148 (42%), Gaps = 10/148 (6%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 +GS D T+ W+ K A +T H+K V + P SAS D ++K ++ G+ Sbjct: 312 TGSHDSTIKFWDLRYGKS-MATITNHKKTVRAMALHPKENDFVSASAD-NIKKFSLPKGE 369 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDI-------RARKLKQDLPGHADE 197 F D+ + ++++G L WD RA + Q PG + Sbjct: 370 FCHNMLSLQRDIINAVAVNEDGVMVTGGDKGGLWFWDWKSGHNFQRAETIVQ--PGSLES 427 Query: 196 ---VYAVDWSPDGEKVVSGGKDRALKLW 122 +YA + G ++V+ D+ +K+W Sbjct: 428 EAGIYAACYDQTGSRLVTCEGDKTIKMW 455
>RBBP7_XENTR (Q6P315) Histone-binding protein RBBP7 (Retinoblastoma-binding| protein 7) (RBBP-7) Length = 425 Score = 73.6 bits (179), Expect = 3e-13 Identities = 54/153 (35%), Positives = 78/153 (50%), Gaps = 15/153 (9%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPK--------ARMTGHQKVVNHVYFSPDGQWL-ASASFDKSV 383 S SDD T+ LW+ IS PK A TGH VV V + + L S + D+ + Sbjct: 194 SASDDHTVCLWD--ISAGPKEGKVVDAKAIFTGHSAVVEDVAWHLLHESLFGSVADDQKL 251 Query: 382 KLWN---GITGKFVTAFRGHVADVYQISWSADSRLLLS-GSKDSTLKVWDIRARKLK-QD 218 +W+ T K + H A+V +S++ S +L+ GS D T+ +WD+R KLK Sbjct: 252 MIWDTRSNTTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHS 311 Query: 217 LPGHADEVYAVDWSPDGEKVV-SGGKDRALKLW 122 H DE++ V WSP E ++ S G DR L +W Sbjct: 312 FESHKDEIFQVHWSPHNETILASSGTDRRLNVW 344 Score = 36.2 bits (82), Expect = 0.059 Identities = 28/82 (34%), Positives = 39/82 (47%), Gaps = 9/82 (10%) Frame = -2 Query: 340 RGHVADVYQISWSAD-SRLLLSGSKDSTLKVWDIRAR-------KLKQDLPGHADEVYAV 185 RGH + Y +SW+++ S LLS S D T+ +WDI A K GH+ V V Sbjct: 173 RGHQKEGYGLSWNSNLSGHLLSASDDHTVCLWDISAGPKEGKVVDAKAIFTGHSAVVEDV 232 Query: 184 DWSPDGEKVV-SGGKDRALKLW 122 W E + S D+ L +W Sbjct: 233 AWHLLHESLFGSVADDQKLMIW 254
>RBBP7_XENLA (Q8AVH1) Histone-binding protein RBBP7 (Retinoblastoma-binding| protein 7) (RBBP-7) Length = 425 Score = 73.6 bits (179), Expect = 3e-13 Identities = 54/153 (35%), Positives = 78/153 (50%), Gaps = 15/153 (9%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPK--------ARMTGHQKVVNHVYFSPDGQWL-ASASFDKSV 383 S SDD T+ LW+ IS PK A TGH VV V + + L S + D+ + Sbjct: 194 SASDDHTVCLWD--ISAGPKEGKVVDAKAVFTGHSAVVEDVAWHLLHESLFGSVADDQKL 251 Query: 382 KLWN---GITGKFVTAFRGHVADVYQISWSADSRLLLS-GSKDSTLKVWDIRARKLK-QD 218 +W+ T K + H A+V +S++ S +L+ GS D T+ +WD+R KLK Sbjct: 252 MIWDTRSNTTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHS 311 Query: 217 LPGHADEVYAVDWSPDGEKVV-SGGKDRALKLW 122 H DE++ V WSP E ++ S G DR L +W Sbjct: 312 FESHKDEIFQVHWSPHNETILASSGTDRRLNVW 344 Score = 36.2 bits (82), Expect = 0.059 Identities = 28/82 (34%), Positives = 39/82 (47%), Gaps = 9/82 (10%) Frame = -2 Query: 340 RGHVADVYQISWSAD-SRLLLSGSKDSTLKVWDIRAR-------KLKQDLPGHADEVYAV 185 RGH + Y +SW+++ S LLS S D T+ +WDI A K GH+ V V Sbjct: 173 RGHQKEGYGLSWNSNLSGHLLSASDDHTVCLWDISAGPKEGKVVDAKAVFTGHSAVVEDV 232 Query: 184 DWSPDGEKVV-SGGKDRALKLW 122 W E + S D+ L +W Sbjct: 233 AWHLLHESLFGSVADDQKLMIW 254
>SPG16_MOUSE (Q8K450) Sperm-associated antigen 16 protein (PF20 protein homolog)| Length = 639 Score = 73.6 bits (179), Expect = 3e-13 Identities = 37/131 (28%), Positives = 65/131 (49%), Gaps = 2/131 (1%) Frame = -2 Query: 508 LWEPTISKQPKARMTG--HQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRG 335 LW+ Q +TG H ++ F P G LA++S D ++KLW+ G+ G Sbjct: 383 LWKMVGLPQGNVLLTGSGHTDWLSGCCFHPSGSKLATSSGDSTIKLWDLNKGECTLTLEG 442 Query: 334 HVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVV 155 H V+ +W + + S S D T K+WD+ + + + L GH D V ++++ P ++ Sbjct: 443 HNHAVWSCTWHSCGDFVASASLDMTSKIWDVNSERCRYTLYGHTDSVNSIEFFPFSNILL 502 Query: 154 SGGKDRALKLW 122 + D+ L +W Sbjct: 503 TASADKTLSVW 513 Score = 67.8 bits (164), Expect = 2e-11 Identities = 43/138 (31%), Positives = 63/138 (45%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 + S D T+ LW+ + + GH V + G ++ASAS D + K+W+ + + Sbjct: 419 TSSGDSTIKLWDLN-KGECTLTLEGHNHAVWSCTWHSCGDFVASASLDMTSKIWDVNSER 477 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 GH V I + S +LL+ S D TL VWD R K +Q L GH V ++ Sbjct: 478 CRYTLYGHTDSVNSIEFFPFSNILLTASADKTLSVWDARTGKCEQSLYGHMHSVNDATFT 537 Query: 175 PDGEKVVSGGKDRALKLW 122 P G + S KLW Sbjct: 538 PRGHIIASCDARGVTKLW 555 Score = 62.0 bits (149), Expect = 1e-09 Identities = 47/180 (26%), Positives = 74/180 (41%), Gaps = 41/180 (22%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 S S D T +W+ S++ + + GH VN + F P L +AS DK++ +W+ TGK Sbjct: 461 SASLDMTSKIWDVN-SERCRYTLYGHTDSVNSIEFFPFSNILLTASADKTLSVWDARTGK 519 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIR--------------------- 239 + GH+ V +++ ++ S K+WD R Sbjct: 520 CEQSLYGHMHSVNDATFTPRGHIIASCDARGVTKLWDFRKLIPIVSIDVGPSSGNEVNFD 579 Query: 238 --ARKLKQ------------------DLPGHADEVYAVDWSPDGEKVVSGGKDRALKLWM 119 R L Q L GH EV++V +S GE + SGG D ++LW+ Sbjct: 580 QSGRVLAQASANGIIHLLDLKSGQIHKLVGHESEVHSVVFSHLGENLYSGGSDGTIRLWI 639 Score = 49.7 bits (117), Expect = 5e-06 Identities = 30/113 (26%), Positives = 48/113 (42%) Frame = -2 Query: 460 HQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLL 281 H+ V+ + P +L S S D+ K+ G + GH + + L Sbjct: 359 HELPVSCIVMHPCRDYLISCSEDRLWKMVGLPQGNVLLTGSGHTDWLSGCCFHPSGSKLA 418 Query: 280 SGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 + S DST+K+WD+ + L GH V++ W G+ V S D K+W Sbjct: 419 TSSGDSTIKLWDLNKGECTLTLEGHNHAVWSCTWHSCGDFVASASLDMTSKIW 471
>RBBP7_CHICK (Q9I8G9) Histone-binding protein RBBP7 (Retinoblastoma-binding| protein 7) (RBBP-7) (Retinoblastoma-binding protein p46) Length = 424 Score = 73.6 bits (179), Expect = 3e-13 Identities = 54/153 (35%), Positives = 78/153 (50%), Gaps = 15/153 (9%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPK--------ARMTGHQKVVNHVYFSPDGQWL-ASASFDKSV 383 S SDD T+ LW+ IS PK A TGH VV V + + L S + D+ + Sbjct: 193 SASDDHTVCLWD--ISAGPKEGKIVDAKAIFTGHSAVVEDVAWHLLHESLFGSVADDQKL 250 Query: 382 KLWN---GITGKFVTAFRGHVADVYQISWSADSRLLLS-GSKDSTLKVWDIRARKLK-QD 218 +W+ T K + H A+V +S++ S +L+ GS D T+ +WD+R KLK Sbjct: 251 MIWDTRSNTTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHS 310 Query: 217 LPGHADEVYAVDWSPDGEKVV-SGGKDRALKLW 122 H DE++ V WSP E ++ S G DR L +W Sbjct: 311 FESHKDEIFQVHWSPHNETILASSGTDRRLNVW 343 Score = 35.4 bits (80), Expect = 0.10 Identities = 27/82 (32%), Positives = 39/82 (47%), Gaps = 9/82 (10%) Frame = -2 Query: 340 RGHVADVYQISWSADSR-LLLSGSKDSTLKVWDIRAR-------KLKQDLPGHADEVYAV 185 RGH + Y +SW+++ + LLS S D T+ +WDI A K GH+ V V Sbjct: 172 RGHQKEGYGLSWNSNLKGHLLSASDDHTVCLWDISAGPKEGKIVDAKAIFTGHSAVVEDV 231 Query: 184 DWSPDGEKVV-SGGKDRALKLW 122 W E + S D+ L +W Sbjct: 232 AWHLLHESLFGSVADDQKLMIW 253
>MORG1_MOUSE (Q9DAJ4) Mitogen-activated protein kinase organizer 1 (MAPK| organizer 1) Length = 315 Score = 73.6 bits (179), Expect = 3e-13 Identities = 38/130 (29%), Positives = 67/130 (51%), Gaps = 3/130 (2%) Frame = -2 Query: 502 EPTISKQPKARMTG---HQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGH 332 +P + P+ RM Q V V F+ DG + + DK++KLWN + G + + GH Sbjct: 7 KPRAPELPQKRMKTLDCSQGAVRAVRFNVDGNYCLTCGSDKTLKLWNPLRGTLLRTYSGH 66 Query: 331 VADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVS 152 +V + S D+ L SG D T+ +WD+ ++ + GHA +V V ++ + ++S Sbjct: 67 GYEVLDAAGSFDNSHLCSGGGDKTVVLWDVATGQVVRKFRGHAGKVNTVQFNEEATVILS 126 Query: 151 GGKDRALKLW 122 G D +++ W Sbjct: 127 GSIDSSVRCW 136 Score = 63.9 bits (154), Expect = 3e-10 Identities = 36/98 (36%), Positives = 53/98 (54%) Frame = -2 Query: 523 DFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTA 344 D T+ LW P + +GH V S D L S DK+V LW+ TG+ V Sbjct: 46 DKTLKLWNPLRGTLLRT-YSGHGYEVLDAAGSFDNSHLCSGGGDKTVVLWDVATGQVVRK 104 Query: 343 FRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARK 230 FRGH V + ++ ++ ++LSGS DS+++ WD R+RK Sbjct: 105 FRGHAGKVNTVQFNEEATVILSGSIDSSVRCWDCRSRK 142 Score = 36.6 bits (83), Expect = 0.045 Identities = 24/89 (26%), Positives = 44/89 (49%), Gaps = 2/89 (2%) Frame = -2 Query: 433 FSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR--LLLSGSKDST 260 FS DGQ +S D +++L + TG+ + + GH Y++ R ++S S+D Sbjct: 199 FSRDGQCTLISSLDSTLRLLDKDTGELLGEYVGHKNQQYKLDCCLSERDTHVVSCSEDGK 258 Query: 259 LKVWDIRARKLKQDLPGHADEVYAVDWSP 173 + WD+ L LP ++ V ++ + P Sbjct: 259 VFFWDLVEGALALALPVGSNVVQSLAYHP 287
>PRP46_KLULA (Q6CKE8) Pre-mRNA-splicing factor PRP46 (Pre-mRNA-processing| protein 46) Length = 434 Score = 73.2 bits (178), Expect = 4e-13 Identities = 39/138 (28%), Positives = 69/138 (50%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 +GS+D T+ +W+ K K + GH V + S ++ SAS DK VK W+ Sbjct: 140 TGSNDTTIKIWDLAAGKL-KITLIGHVMSVRDIAISKRHPYMFSASEDKLVKCWDLERNT 198 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 + F GH++ V+ + ++ + +D+ +++WDIR+R LPGH + V Sbjct: 199 AIRDFHGHLSGVHTVDVHPSLDIIATAGRDAVVRLWDIRSRSEIMVLPGHKSPINKVKCL 258 Query: 175 PDGEKVVSGGKDRALKLW 122 P +++S D ++LW Sbjct: 259 PVDPQIISCSGDATVRLW 276 Score = 72.4 bits (176), Expect = 7e-13 Identities = 37/117 (31%), Positives = 57/117 (48%), Gaps = 1/117 (0%) Frame = -2 Query: 469 MTGHQKVVNHVYFSP-DGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADS 293 + GH V V P D +W A+ S D ++K+W+ GK GHV V I+ S Sbjct: 118 INGHTGWVRCVCVDPVDNEWFATGSNDTTIKIWDLAAGKLKITLIGHVMSVRDIAISKRH 177 Query: 292 RLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 + S S+D +K WD+ +D GH V+ VD P + + + G+D ++LW Sbjct: 178 PYMFSASEDKLVKCWDLERNTAIRDFHGHLSGVHTVDVHPSLDIIATAGRDAVVRLW 234 Score = 30.8 bits (68), Expect = 2.5 Identities = 19/72 (26%), Positives = 33/72 (45%) Frame = -2 Query: 523 DFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTA 344 D + LW+ S+ + GH+ +N V P + S S D +V+LW+ I GK Sbjct: 228 DAVVRLWDIR-SRSEIMVLPGHKSPINKVKCLPVDPQIISCSGDATVRLWDIIAGKASKV 286 Query: 343 FRGHVADVYQIS 308 H ++ ++ Sbjct: 287 LTHHSRNIRDLT 298
>A16L1_MOUSE (Q8C0J2) Autophagy-related protein 16-1 (APG16-like 1)| Length = 607 Score = 73.2 bits (178), Expect = 4e-13 Identities = 39/115 (33%), Positives = 58/115 (50%), Gaps = 2/115 (1%) Frame = -2 Query: 460 HQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK--FVTAFRGHVADVYQISWSADSRL 287 H VN V FSP + LA+ D+ VKLW K F + G A + I + + Sbjct: 321 HDGEVNAVQFSPGSRLLATGGMDRRVKLWEAFGDKCEFKGSLSGSNAGITSIEFDSAGAY 380 Query: 286 LLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 LL+ S D ++W + +L+ L GH+ +V + + D ++VSG DR LKLW Sbjct: 381 LLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLW 435 Score = 52.0 bits (123), Expect = 1e-06 Identities = 36/141 (25%), Positives = 68/141 (48%), Gaps = 3/141 (2%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISK-QPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITG 359 +G D + LWE K + K ++G + + F G +L +AS D + ++W Sbjct: 339 TGGMDRRVKLWEAFGDKCEFKGSLSGSNAGITSIEFDSAGAYLLAASNDFASRIWTVDDY 398 Query: 358 KFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARK-LKQDLPGHA-DEVYAV 185 + GH V + D+ ++SGS D TLK+WD+R++ +K G + +++ Sbjct: 399 RLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSKVCIKTVFAGSSCNDIVCT 458 Query: 184 DWSPDGEKVVSGGKDRALKLW 122 + + V+SG D+ ++ W Sbjct: 459 E-----QCVMSGHFDKKIRFW 474 Score = 47.4 bits (111), Expect = 3e-05 Identities = 41/142 (28%), Positives = 64/142 (45%), Gaps = 4/142 (2%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SGS D T+ LW+ K G N + + Q + S FDK ++ W+ I + Sbjct: 425 SGSHDRTLKLWDLRSKVCIKTVFAGSS--CNDIVCTE--QCVMSGHFDKKIRFWD-IRSE 479 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQ--DLPGH--ADEVYA 188 V + + + + + LLS S+D LKV D+R +KQ PG + Sbjct: 480 SVVREMELLGKITALDLNPERTELLSCSRDDLLKVIDLRTNAVKQTFSAPGFKCGSDWTR 539 Query: 187 VDWSPDGEKVVSGGKDRALKLW 122 V +SPDG V +G + +L +W Sbjct: 540 VVFSPDGSYVAAGSAEGSLYVW 561 Score = 40.8 bits (94), Expect = 0.002 Identities = 22/70 (31%), Positives = 37/70 (52%), Gaps = 1/70 (1%) Frame = -2 Query: 328 ADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPG-HADEVYAVDWSPDGEKVVS 152 +D ++ +S D + +GS + +L VW + K+++ L H+ + AV W+P G VVS Sbjct: 535 SDWTRVVFSPDGSYVAAGSAEGSLYVWSVLTGKVEKVLSKQHSSSINAVAWAPSGLHVVS 594 Query: 151 GGKDRALKLW 122 K LW Sbjct: 595 VDKGSRAVLW 604 Score = 40.4 bits (93), Expect = 0.003 Identities = 19/65 (29%), Positives = 36/65 (55%), Gaps = 1/65 (1%) Frame = -2 Query: 439 VYFSPDGQWLASASFDKSVKLWNGITGKFVTAF-RGHVADVYQISWSADSRLLLSGSKDS 263 V FSPDG ++A+ S + S+ +W+ +TGK + H + + ++W+ ++S K S Sbjct: 540 VVFSPDGSYVAAGSAEGSLYVWSVLTGKVEKVLSKQHSSSINAVAWAPSGLHVVSVDKGS 599 Query: 262 TLKVW 248 +W Sbjct: 600 RAVLW 604
>APAF_MOUSE (O88879) Apoptotic protease-activating factor 1 (Apaf-1)| Length = 1249 Score = 73.2 bits (178), Expect = 4e-13 Identities = 40/115 (34%), Positives = 61/115 (53%), Gaps = 2/115 (1%) Frame = -2 Query: 460 HQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVY--QISWSADSRL 287 H+ V FS D ++A+ S DK VK+W+ TGK V + H V + S++ L Sbjct: 656 HEDEVLCCAFSSDDSYIATCSADKKVKIWDSATGKLVHTYDEHSEQVNCCHFTNSSNHLL 715 Query: 286 LLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 L +GS D LK+WD+ ++ + + GH + V +SPD E + S D L+LW Sbjct: 716 LATGSNDFFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDELLASCSADGTLRLW 770 Score = 72.8 bits (177), Expect = 6e-13 Identities = 41/114 (35%), Positives = 61/114 (53%) Frame = -2 Query: 463 GHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLL 284 GH+K V H+ F+ DG+ L S+S D +++WN TG +V + H V DSR L Sbjct: 1001 GHKKAVRHIQFTADGKTLISSSEDSVIQVWNWQTGDYV-FLQAHQETVKDFRLLQDSR-L 1058 Query: 283 LSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 LS S D T+KVW++ ++++D H V + S D K S D+ K+W Sbjct: 1059 LSWSFDGTVKVWNVITGRIERDFTCHQGTVLSCAISSDATKFSSTSADKTAKIW 1112 Score = 62.8 bits (151), Expect = 6e-10 Identities = 49/193 (25%), Positives = 79/193 (40%), Gaps = 55/193 (28%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITG- 359 +GS+DF + LW+ K+ + M GH VNH FSPD + LAS S D +++LW+ + Sbjct: 718 TGSNDFFLKLWDLN-QKECRNTMFGHTNSVNHCRFSPDDELLASCSADGTLRLWDVRSAN 776 Query: 358 --------KFVTAFRGHVADVYQI----SWSADSRLLLSGSKDSTL-------------- 257 +F + DV I SWSAD ++ +K+ L Sbjct: 777 ERKSINVKRFFLSSEDPPEDVEVIVKCCSWSADGDKIIVAAKNKVLLFDIHTSGLLAEIH 836 Query: 256 ----------------------------KVWDIRARKLKQDLPGHADEVYAVDWSPDGEK 161 ++W+I +R D GH V+ V +SPDG Sbjct: 837 TGHHSTIQYCDFSPYDHLAVIALSQYCVELWNIDSRLKVADCRGHLSWVHGVMFSPDGSS 896 Query: 160 VVSGGKDRALKLW 122 ++ D+ +++W Sbjct: 897 FLTASDDQTIRVW 909 Score = 58.5 bits (140), Expect = 1e-08 Identities = 36/116 (31%), Positives = 54/116 (46%) Frame = -2 Query: 469 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 290 + HQ+ V D + L S SFD +VK+WN ITG+ F H V + S+D+ Sbjct: 1040 LQAHQETVKDFRLLQDSR-LLSWSFDGTVKVWNVITGRIERDFTCHQGTVLSCAISSDAT 1098 Query: 289 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 S S D T K+W +L GH V +S DG + +G + +++W Sbjct: 1099 KFSSTSADKTAKIWSFDLLSPLHELKGHNGCVRCSAFSLDGILLATGDDNGEIRIW 1154 Score = 46.6 bits (109), Expect = 4e-05 Identities = 24/76 (31%), Positives = 38/76 (50%) Frame = -2 Query: 466 TGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRL 287 TGH + + FSP A V+LWN + V RGH++ V+ + +S D Sbjct: 837 TGHHSTIQYCDFSPYDHLAVIALSQYCVELWNIDSRLKVADCRGHLSWVHGVMFSPDGSS 896 Query: 286 LLSGSKDSTLKVWDIR 239 L+ S D T++VW+ + Sbjct: 897 FLTASDDQTIRVWETK 912 Score = 38.1 bits (87), Expect = 0.016 Identities = 32/160 (20%), Positives = 62/160 (38%), Gaps = 37/160 (23%) Frame = -2 Query: 490 SKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLW--------------------- 374 S+ A GH V+ V FSPDG +AS D+++++W Sbjct: 871 SRLKVADCRGHLSWVHGVMFSPDGSSFLTASDDQTIRVWETKKVCKNSAIVLKQEIDVVF 930 Query: 373 ----------NGITG-KFVTAFRGHV-----ADVYQISWSADSRLLLSGSKDSTLKVWDI 242 + I G + + G + A V S + G +D +K+ ++ Sbjct: 931 QENETMVLAVDNIRGLQLIAGKTGQIDYLPEAQVSCCCLSPHLEYVAFGDEDGAIKIIEL 990 Query: 241 RARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 ++ GH V + ++ DG+ ++S +D +++W Sbjct: 991 PNNRVFSSGVGHKKAVRHIQFTADGKTLISSSEDSVIQVW 1030 Score = 34.7 bits (78), Expect = 0.17 Identities = 33/131 (25%), Positives = 53/131 (40%), Gaps = 9/131 (6%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 S S D T +W + P + GH V FS DG LA+ + +++WN G+ Sbjct: 1102 STSADKTAKIWSFDLLS-PLHELKGHNGCVRCSAFSLDGILLATGDDNGEIRIWNVSDGQ 1160 Query: 355 F------VTAFRG---HVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHA 203 ++ G H V + +S DS+ L+S LK W++ Q + Sbjct: 1161 LLHSCAPISVEEGTATHGGWVTDVCFSPDSKTLVSAG--GYLKWWNVATGDSSQTFYTNG 1218 Query: 202 DEVYAVDWSPD 170 + + SPD Sbjct: 1219 TNLKKIHVSPD 1229
>PRP46_CANGA (Q6FJZ9) Pre-mRNA-splicing factor PRP46 (Pre-mRNA-processing| protein 46) Length = 427 Score = 73.2 bits (178), Expect = 4e-13 Identities = 40/138 (28%), Positives = 68/138 (49%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 +GS+D T+ +W K K + H V + S ++ S S DK+VK W+ Sbjct: 133 TGSNDKTIKIWNLASGKL-KVTLKAHDMTVRDLAISNRHPYMFSVSEDKTVKCWDLEKNT 191 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 + + GH++ V+ + ++++ +DS +KVWDIR R LPGH + V Sbjct: 192 AIRNYHGHLSGVHTVDIHPTVDVVVTAGRDSVVKVWDIRTRLPVMTLPGHKGPITKVRCL 251 Query: 175 PDGEKVVSGGKDRALKLW 122 P +V+S D +++LW Sbjct: 252 PVDPQVISSSVDASIRLW 269 Score = 71.6 bits (174), Expect = 1e-12 Identities = 33/101 (32%), Positives = 54/101 (53%) Frame = -2 Query: 424 DGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD 245 D +W A+ S DK++K+WN +GK + H V ++ S + S S+D T+K WD Sbjct: 127 DNEWFATGSNDKTIKIWNLASGKLKVTLKAHDMTVRDLAISNRHPYMFSVSEDKTVKCWD 186 Query: 244 IRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 + ++ GH V+ VD P + VV+ G+D +K+W Sbjct: 187 LEKNTAIRNYHGHLSGVHTVDIHPTVDVVVTAGRDSVVKVW 227 Score = 40.0 bits (92), Expect = 0.004 Identities = 32/122 (26%), Positives = 54/122 (44%), Gaps = 1/122 (0%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKAR-MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITG 359 S S+D T+ W+ + K R GH V+ V P + +A D VK+W+ T Sbjct: 175 SVSEDKTVKCWD--LEKNTAIRNYHGHLSGVHTVDIHPTVDVVVTAGRDSVVKVWDIRTR 232 Query: 358 KFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDW 179 V GH + ++ ++S S D+++++WD+ A K + L H V + Sbjct: 233 LPVMTLPGHKGPITKVRCLPVDPQVISSSVDASIRLWDLVAGKSMKVLTHHQRTVRDISV 292 Query: 178 SP 173 P Sbjct: 293 HP 294
>WSB2_HUMAN (Q9NYS7) WD repeat and SOCS box-containing protein 2 (WSB-2) (CS| box-containing WD protein) Length = 404 Score = 72.8 bits (177), Expect = 6e-13 Identities = 44/140 (31%), Positives = 74/140 (52%), Gaps = 2/140 (1%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQW-LASASFDKSVKLWN-GIT 362 +G +D + +WE ++GHQ VV + F+P G L SAS DK++++W+ Sbjct: 128 TGLNDGQIKIWEVQTGLL-LLNLSGHQDVVRDLSFTPSGSLILVSASRDKTLRIWDLNKH 186 Query: 361 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 182 GK + GH+ VY S S D +L S + + ++ +W +R+ L + L GH V + D Sbjct: 187 GKQIQVLSGHLQWVYCCSISPDCSMLCSAAGEKSVFLWSMRSYTLIRKLEGHQSSVVSCD 246 Query: 181 WSPDGEKVVSGGKDRALKLW 122 +SPD +V+ D + +W Sbjct: 247 FSPDSALLVTASYDTNVIMW 266 Score = 63.2 bits (152), Expect = 5e-10 Identities = 44/150 (29%), Positives = 71/150 (47%), Gaps = 12/150 (8%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 S S D T+ +W+ + ++GH + V SPD L SA+ +KSV LW+ + Sbjct: 171 SASRDKTLRIWDLNKHGKQIQVLSGHLQWVYCCSISPDCSMLCSAAGEKSVFLWSMRSYT 230 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD----IRARKL--------KQDLP 212 + GH + V +S DS LL++ S D+ + +WD R R L D Sbjct: 231 LIRKLEGHQSSVVSCDFSPDSALLVTASYDTNVIMWDPYTGERLRSLHHTQVDPAMDDSD 290 Query: 211 GHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 H + +V +SP+G + + DR L++W Sbjct: 291 VHISSLRSVCFSPEGLYLATVADDRLLRIW 320 Score = 56.2 bits (134), Expect = 6e-08 Identities = 33/99 (33%), Positives = 52/99 (52%), Gaps = 2/99 (2%) Frame = -2 Query: 412 LASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWS-ADSRLLLSGSKDSTLKVWDIRA 236 LA+ D +K+W TG + GH V +S++ + S +L+S S+D TL++WD+ Sbjct: 126 LATGLNDGQIKIWEVQTGLLLLNLSGHQDVVRDLSFTPSGSLILVSASRDKTLRIWDLNK 185 Query: 235 R-KLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 K Q L GH VY SPD + S ++++ LW Sbjct: 186 HGKQIQVLSGHLQWVYCCSISPDCSMLCSAAGEKSVFLW 224 Score = 46.2 bits (108), Expect = 6e-05 Identities = 35/151 (23%), Positives = 67/151 (44%), Gaps = 13/151 (8%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 S + + ++FLW S ++ GHQ V FSPD L +AS+D +V +W+ TG+ Sbjct: 214 SAAGEKSVFLWSMR-SYTLIRKLEGHQSSVVSCDFSPDSALLVTASYDTNVIMWDPYTGE 272 Query: 355 FVTAFRG------------HVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLP 212 + + H++ + + +S + L + + D L++W A +LK + Sbjct: 273 RLRSLHHTQVDPAMDDSDVHISSLRSVCFSPEGLYLATVADDRLLRIW---ALELKTPIA 329 Query: 211 -GHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 + P G + +G +D ++ W Sbjct: 330 FAPMTNGLCCTFFPHGGVIATGTRDGHVQFW 360 Score = 43.1 bits (100), Expect = 5e-04 Identities = 18/57 (31%), Positives = 34/57 (59%), Gaps = 1/57 (1%) Frame = -2 Query: 289 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKV-VSGGKDRALKLW 122 +L +G D +K+W+++ L +L GH D V + ++P G + VS +D+ L++W Sbjct: 125 VLATGLNDGQIKIWEVQTGLLLLNLSGHQDVVRDLSFTPSGSLILVSASRDKTLRIW 181
>WDR12_HUMAN (Q9GZL7) WD-repeat protein 12 (YTM1 homolog)| Length = 423 Score = 72.8 bits (177), Expect = 6e-13 Identities = 52/140 (37%), Positives = 79/140 (56%), Gaps = 5/140 (3%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT-- 362 S S D T+ +W+ S K+ +TG+ KV N + +SP + LAS S D+ ++LW+ T Sbjct: 273 SASWDHTIRVWDVE-SGSLKSTLTGN-KVFNCISYSPLCKRLASGSTDRHIRLWDPRTKD 330 Query: 361 GKFVT-AFRGHVADVYQISWS-ADSRLLLSGSKDSTLKVWDIRARKLK-QDLPGHADEVY 191 G V+ + H V + WS + L+SGS D+ +K+WD R+ K DL H D+V Sbjct: 331 GSLVSLSLTSHTGWVTSVKWSPTHEQQLISGSLDNIVKLWDTRSCKAPLYDLAAHEDKVL 390 Query: 190 AVDWSPDGEKVVSGGKDRAL 131 +VDW+ G ++SGG D L Sbjct: 391 SVDWTDTG-LLLSGGADNKL 409 Score = 66.2 bits (160), Expect = 5e-11 Identities = 41/134 (30%), Positives = 74/134 (55%), Gaps = 5/134 (3%) Frame = -2 Query: 493 ISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQ 314 +++ P ++GH + V+ V +S D + + SAS+D ++++W+ +G + G+ V+ Sbjct: 245 LTRTPIVTLSGHMEAVSSVLWS-DAEEICSASWDHTIRVWDVESGSLKSTLTGN--KVFN 301 Query: 313 -ISWSADSRLLLSGSKDSTLKVWDIRARK---LKQDLPGHADEVYAVDWSPDGEK-VVSG 149 IS+S + L SGS D +++WD R + + L H V +V WSP E+ ++SG Sbjct: 302 CISYSPLCKRLASGSTDRHIRLWDPRTKDGSLVSLSLTSHTGWVTSVKWSPTHEQQLISG 361 Query: 148 GKDRALKLWMN*AC 107 D +KLW +C Sbjct: 362 SLDNIVKLWDTRSC 375 Score = 64.7 bits (156), Expect = 2e-10 Identities = 45/168 (26%), Positives = 75/168 (44%), Gaps = 30/168 (17%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARM---TGHQKVVNHVYFSPDGQWLASASFDKSVKLWN-- 371 S S D T+ LWE + + + GH V+ + G S S+DK +K+W+ Sbjct: 160 SASMDQTILLWEWNVERNKVKALHCCRGHAGSVDSIAVDGSGTKFCSGSWDKMLKIWSTV 219 Query: 370 ------------------------GITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDS 263 G+T + GH+ V + WS D+ + S S D Sbjct: 220 PTDEEDEMEESTNRPRKKQKTEQLGLTRTPIVTLSGHMEAVSSVLWS-DAEEICSASWDH 278 Query: 262 TLKVWDIRARKLKQDLPGHADEVY-AVDWSPDGEKVVSGGKDRALKLW 122 T++VWD+ + LK L G ++V+ + +SP +++ SG DR ++LW Sbjct: 279 TIRVWDVESGSLKSTLTG--NKVFNCISYSPLCKRLASGSTDRHIRLW 324 Score = 58.2 bits (139), Expect = 1e-08 Identities = 34/106 (32%), Positives = 56/106 (52%), Gaps = 7/106 (6%) Frame = -2 Query: 418 QWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISW---SADSRLLLSGSKDSTLKVW 248 +W+ + S+DK+ ++W+ + GK + GH V ++W + S LLLS S D T+ +W Sbjct: 112 EWILTGSYDKTSRIWS-LEGKSIMTIVGHTDVVKDVAWVKKDSLSCLLLSASMDQTILLW 170 Query: 247 D--IRARKLK--QDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 + + K+K GHA V ++ G K SG D+ LK+W Sbjct: 171 EWNVERNKVKALHCCRGHAGSVDSIAVDGSGTKFCSGSWDKMLKIW 216
>WDR1_CHICK (O93277) WD-repeat protein 1 (Actin-interacting protein 1) (AIP1)| Length = 609 Score = 72.8 bits (177), Expect = 6e-13 Identities = 44/106 (41%), Positives = 59/106 (55%), Gaps = 3/106 (2%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 +GSDD +E K K ++ H + VN V FSPDG A+AS D + +++G TG+ Sbjct: 166 TGSDDNCAAFFEGPPFKF-KFTLSDHTRFVNCVRFSPDGNRFATASADGQIFIYDGKTGE 224 Query: 355 FVTAFRG---HVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKL 227 V A G H +Y ISWS DS LLS S D T K+WD+ A + Sbjct: 225 KVCALGGGKAHDGGIYAISWSPDSSQLLSASGDKTAKIWDVGANSV 270 Score = 59.3 bits (142), Expect = 7e-09 Identities = 38/135 (28%), Positives = 60/135 (44%), Gaps = 4/135 (2%) Frame = -2 Query: 514 MFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQW-LASASFDKSVKLWNGITGKFVTAFR 338 +FLW+ S +TGH KV+N V + LA+ S D + G KF Sbjct: 132 VFLWD---SGSSVGEITGHNKVINSVDIKQTRPYRLATGSDDNCAAFFEGPPFKFKFTLS 188 Query: 337 GHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPG---HADEVYAVDWSPDG 167 H V + +S D + S D + ++D + + L G H +YA+ WSPD Sbjct: 189 DHTRFVNCVRFSPDGNRFATASADGQIFIYDGKTGEKVCALGGGKAHDGGIYAISWSPDS 248 Query: 166 EKVVSGGKDRALKLW 122 +++S D+ K+W Sbjct: 249 SQLLSASGDKTAKIW 263 Score = 40.8 bits (94), Expect = 0.002 Identities = 31/112 (27%), Positives = 50/112 (44%), Gaps = 3/112 (2%) Frame = -2 Query: 448 VNHVYFSPDGQWLASASFDKSVKLWNGITGKFV-TAFRGHVADVYQISWSADSRLLLSGS 272 V + +S DG +LA +K V +++ G F GH A V I+WS D+ SG Sbjct: 494 VTDLAYSHDGAFLAVCDANKVVTVFSVPDGYVEHNVFYGHHAKVVCIAWSPDNEHFASGG 553 Query: 271 KDSTLKVWDIRARKLKQDLPG--HADEVYAVDWSPDGEKVVSGGKDRALKLW 122 D + VW + + + +P V + W D +V+ D ++K W Sbjct: 554 MDMMVYVWTVSDPETRIKIPDAHRLHHVSGLAWL-DEHTLVTTSHDASVKEW 604 Score = 35.0 bits (79), Expect = 0.13 Identities = 28/109 (25%), Positives = 51/109 (46%), Gaps = 7/109 (6%) Frame = -2 Query: 427 PDGQWLASASFDKSVKLWNGITGKFVTA------FRGHVADVYQISWSADSRLLLSGSKD 266 P G +A D +V+L++ I G + + +G V D +++S D L + Sbjct: 457 PGGGSVAVGGTDGNVRLYS-IQGTSLKSDDKTLEAKGPVTD---LAYSHDGAFLAVCDAN 512 Query: 265 STLKVWDIRARKLKQDL-PGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 + V+ + ++ ++ GH +V + WSPD E SGG D + +W Sbjct: 513 KVVTVFSVPDGYVEHNVFYGHHAKVVCIAWSPDNEHFASGGMDMMVYVW 561 Score = 33.1 bits (74), Expect = 0.50 Identities = 38/147 (25%), Positives = 63/147 (42%), Gaps = 9/147 (6%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTG--HQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 362 + S D +F+++ ++ A G H + + +SPD L SAS DK+ K+W+ Sbjct: 208 TASADGQIFIYDGKTGEKVCALGGGKAHDGGIYAISWSPDSSQLLSASGDKTAKIWDVGA 267 Query: 361 GKFVTAFR--GHVADVYQIS--WSADSRLLLSGSKDSTLKVWD-IRARKLKQDLPGHADE 197 V+ F +V D Q+ W D LLS S + D K + + GH+ Sbjct: 268 NSVVSTFNMGSNVLD-QQLGCLWQKDH--LLSLSLSGYINYLDKNNPDKPLRVIKGHSKS 324 Query: 196 VYAVDWSPDGEK--VVSGGKDRALKLW 122 + + +G K + SG D + W Sbjct: 325 IQCLTVHKNGGKSYIYSGSNDGHINYW 351 Score = 32.0 bits (71), Expect = 1.1 Identities = 24/78 (30%), Positives = 35/78 (44%), Gaps = 4/78 (5%) Frame = -2 Query: 463 GHQKVVNHVYFSPDGQWLASASFDKSVKLWN----GITGKFVTAFRGHVADVYQISWSAD 296 GH V + +SPD + AS D V +W K A R H V ++W D Sbjct: 532 GHHAKVVCIAWSPDNEHFASGGMDMMVYVWTVSDPETRIKIPDAHRLH--HVSGLAW-LD 588 Query: 295 SRLLLSGSKDSTLKVWDI 242 L++ S D+++K W I Sbjct: 589 EHTLVTTSHDASVKEWSI 606
>PEX7_MOUSE (P97865) Peroxisomal targeting signal 2 receptor (PTS2 receptor)| (Peroxin-7) Length = 318 Score = 72.8 bits (177), Expect = 6e-13 Identities = 43/140 (30%), Positives = 70/140 (50%), Gaps = 4/140 (2%) Frame = -2 Query: 529 SDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDG--QWLASASFDKSVKLWNGITGK 356 S D ++ LW+ + P H + V V +S Q + S S+D++VK+W+ G Sbjct: 82 SGDGSLQLWDTAKATGPLQVYKEHTQEVYSVDWSQTRGEQLVVSGSWDQTVKVWDPTVGN 141 Query: 355 FVTAFRGHVADVYQISWSAD-SRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDW 179 + FRGH + +Y WS S S D TL++WD++ ++ +P H E+ + DW Sbjct: 142 SLCTFRGHESVIYSTIWSPHIPGCFASASGDQTLRIWDVKTTGVRIVIPAHQTEILSCDW 201 Query: 178 SPDGEK-VVSGGKDRALKLW 122 E VV+G D +L+ W Sbjct: 202 CKYNENLVVTGAVDCSLRGW 221 Score = 57.0 bits (136), Expect = 3e-08 Identities = 40/142 (28%), Positives = 70/142 (49%), Gaps = 4/142 (2%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPD-GQWLASASFDKSVKLWNGITG 359 SGS D T+ +W+PT+ GH+ V+ +SP ASAS D+++++W+ T Sbjct: 125 SGSWDQTVKVWDPTVGNS-LCTFRGHESVIYSTIWSPHIPGCFASASGDQTLRIWDVKTT 183 Query: 358 KFVTAFRGHVADVYQISW-SADSRLLLSGSKDSTLKVWDIR-ARKLKQDLPGHADEVYAV 185 H ++ W + L+++G+ D +L+ WD+R R+ +L GH + V Sbjct: 184 GVRIVIPAHQTEILSCDWCKYNENLVVTGAVDCSLRGWDLRNVRQPVFELLGHTYAIRRV 243 Query: 184 DWSPDGEKVV-SGGKDRALKLW 122 +SP V+ S D ++ W Sbjct: 244 KFSPFHASVLASCSYDFTVRFW 265 Score = 36.6 bits (83), Expect = 0.045 Identities = 19/56 (33%), Positives = 30/56 (53%), Gaps = 1/56 (1%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSP-DGQWLASASFDKSVKLWN 371 +G+ D ++ W+ +QP + GH + V FSP LAS S+D +V+ WN Sbjct: 211 TGAVDCSLRGWDLRNVRQPVFELLGHTYAIRRVKFSPFHASVLASCSYDFTVRFWN 266
>PEX7_CRIGR (Q8R537) Peroxisomal targeting signal 2 receptor (PTS2 receptor)| (Peroxin-7) Length = 318 Score = 72.8 bits (177), Expect = 6e-13 Identities = 43/140 (30%), Positives = 70/140 (50%), Gaps = 4/140 (2%) Frame = -2 Query: 529 SDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDG--QWLASASFDKSVKLWNGITGK 356 S D ++ LW+ + P H + V V +S Q + S S+D++VK+W+ G Sbjct: 82 SGDGSLQLWDTAKATGPLQVYKEHTQEVYSVDWSQTRGEQLVVSGSWDQTVKVWDPTVGN 141 Query: 355 FVTAFRGHVADVYQISWSAD-SRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDW 179 + FRGH + +Y WS S S D TL++WD++ ++ +P H E+ + DW Sbjct: 142 SLCTFRGHESVIYSTIWSPHIPGCFASASGDQTLRIWDVKTAGVRIVIPAHQTEILSCDW 201 Query: 178 SPDGEK-VVSGGKDRALKLW 122 E VV+G D +L+ W Sbjct: 202 CKYNENLVVTGAVDCSLRGW 221 Score = 57.8 bits (138), Expect = 2e-08 Identities = 40/142 (28%), Positives = 70/142 (49%), Gaps = 4/142 (2%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPD-GQWLASASFDKSVKLWNGITG 359 SGS D T+ +W+PT+ GH+ V+ +SP ASAS D+++++W+ T Sbjct: 125 SGSWDQTVKVWDPTVGNS-LCTFRGHESVIYSTIWSPHIPGCFASASGDQTLRIWDVKTA 183 Query: 358 KFVTAFRGHVADVYQISW-SADSRLLLSGSKDSTLKVWDIR-ARKLKQDLPGHADEVYAV 185 H ++ W + L+++G+ D +L+ WD+R R+ +L GH + V Sbjct: 184 GVRIVIPAHQTEILSCDWCKYNENLVVTGAVDCSLRGWDLRNVRQPVFELLGHTYAIRRV 243 Query: 184 DWSPDGEKVV-SGGKDRALKLW 122 +SP V+ S D ++ W Sbjct: 244 KFSPFHASVLASCSYDFTVRFW 265 Score = 36.6 bits (83), Expect = 0.045 Identities = 19/56 (33%), Positives = 30/56 (53%), Gaps = 1/56 (1%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSP-DGQWLASASFDKSVKLWN 371 +G+ D ++ W+ +QP + GH + V FSP LAS S+D +V+ WN Sbjct: 211 TGAVDCSLRGWDLRNVRQPVFELLGHTYAIRRVKFSPFHASVLASCSYDFTVRFWN 266
>MORG1_RAT (Q5BLX8) Mitogen-activated protein kinase organizer 1 (MAPK| organizer 1) Length = 315 Score = 72.8 bits (177), Expect = 6e-13 Identities = 35/126 (27%), Positives = 65/126 (51%) Frame = -2 Query: 499 PTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADV 320 P + ++ + Q V V F+ DG + + DK++KLWN + G + + GH +V Sbjct: 11 PELPRKQLKTLDCGQGAVRAVRFNVDGNYCLTCGSDKTLKLWNPLRGTLLRTYSGHGYEV 70 Query: 319 YQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKD 140 + S D+ L SG D T+ +WD+ ++ + GHA +V V ++ + ++SG D Sbjct: 71 LDAAGSFDNSHLCSGGGDKTVVLWDVATGQVVRKFRGHAGKVNTVQFNEEATVILSGSID 130 Query: 139 RALKLW 122 +++ W Sbjct: 131 SSVRCW 136 Score = 63.9 bits (154), Expect = 3e-10 Identities = 36/98 (36%), Positives = 53/98 (54%) Frame = -2 Query: 523 DFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTA 344 D T+ LW P + +GH V S D L S DK+V LW+ TG+ V Sbjct: 46 DKTLKLWNPLRGTLLRT-YSGHGYEVLDAAGSFDNSHLCSGGGDKTVVLWDVATGQVVRK 104 Query: 343 FRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARK 230 FRGH V + ++ ++ ++LSGS DS+++ WD R+RK Sbjct: 105 FRGHAGKVNTVQFNEEATVILSGSIDSSVRCWDCRSRK 142 Score = 37.0 bits (84), Expect = 0.035 Identities = 24/89 (26%), Positives = 44/89 (49%), Gaps = 2/89 (2%) Frame = -2 Query: 433 FSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR--LLLSGSKDST 260 FS DGQ +S D +++L + TG+ + + GH Y++ R ++S S+D Sbjct: 199 FSRDGQCTLISSLDSTLRLLDKDTGELLGEYVGHKNQKYKLDCCLSERDTHVVSCSEDGK 258 Query: 259 LKVWDIRARKLKQDLPGHADEVYAVDWSP 173 + WD+ L LP ++ V ++ + P Sbjct: 259 VFFWDLVEGSLALALPVGSNVVQSLAYHP 287
>LIN23_CAEEL (Q09990) F-box/WD-repeat protein lin-23 (Abnormal cell lineage| protein 23) Length = 665 Score = 72.4 bits (176), Expect = 7e-13 Identities = 43/138 (31%), Positives = 78/138 (56%), Gaps = 2/138 (1%) Frame = -2 Query: 529 SDDFTMFLWEPTISKQPKAR--MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 S D ++ +W+ + R + GH+ VN V F D +++ SAS D+++K+W+ T + Sbjct: 319 SKDRSIAVWDMVSPRDITIRRVLVGHRAAVNVVDF--DDRYIVSASGDRTIKVWSMDTLE 376 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 FV GH + + + RL++SGS D+T+++WDI + + L GH + V + + Sbjct: 377 FVRTLAGHRRGIACLQYRG--RLVVSGSSDNTIRLWDIHSGVCLRVLEGHEELVRCIRF- 433 Query: 175 PDGEKVVSGGKDRALKLW 122 D +++VSG D +K+W Sbjct: 434 -DEKRIVSGAYDGKIKVW 450 Score = 50.4 bits (119), Expect = 3e-06 Identities = 38/141 (26%), Positives = 72/141 (51%), Gaps = 3/141 (2%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SG D T+ +W+ + ++GH V + + D + + S S D +V++W+ TG+ Sbjct: 237 SGLRDNTIKIWDRKDYSCSRI-LSGHTGSVLCLQY--DNRVIISGSSDATVRVWDVETGE 293 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDI---RARKLKQDLPGHADEVYAV 185 + H V + ++ + ++++ SKD ++ VWD+ R +++ L GH V V Sbjct: 294 CIKTLIHHCEAVLHLRFA--NGIMVTCSKDRSIAVWDMVSPRDITIRRVLVGHRAAVNVV 351 Query: 184 DWSPDGEKVVSGGKDRALKLW 122 D+ D +VS DR +K+W Sbjct: 352 DF--DDRYIVSASGDRTIKVW 370 Score = 47.4 bits (111), Expect = 3e-05 Identities = 26/101 (25%), Positives = 52/101 (51%) Frame = -2 Query: 424 DGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD 245 D + S D ++K+W+ GH V + + D+R+++SGS D+T++VWD Sbjct: 231 DDDKIVSGLRDNTIKIWDRKDYSCSRILSGHTGSVLCLQY--DNRVIISGSSDATVRVWD 288 Query: 244 IRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 + + + L H + V + ++ +V+ KDR++ +W Sbjct: 289 VETGECIKTLIHHCEAVLHLRFA--NGIMVTCSKDRSIAVW 327
>A16L1_HUMAN (Q676U5) Autophagy-related protein 16-1 (APG16-like 1)| Length = 607 Score = 72.4 bits (176), Expect = 7e-13 Identities = 39/115 (33%), Positives = 59/115 (51%), Gaps = 2/115 (1%) Frame = -2 Query: 460 HQKVVNHVYFSPDGQWLASASFDKSVKLWN--GITGKFVTAFRGHVADVYQISWSADSRL 287 H VN V FSP + LA+ D+ VKLW G +F + G A + I + + Sbjct: 321 HDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAGSY 380 Query: 286 LLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 LL+ S D ++W + +L+ L GH+ +V + + D ++VSG DR LKLW Sbjct: 381 LLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLW 435 Score = 52.0 bits (123), Expect = 1e-06 Identities = 36/141 (25%), Positives = 68/141 (48%), Gaps = 3/141 (2%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISK-QPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITG 359 +G D + LWE K + K ++G + + F G +L +AS D + ++W Sbjct: 339 TGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAGSYLLAASNDFASRIWTVDDY 398 Query: 358 KFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARK-LKQDLPGHA-DEVYAV 185 + GH V + D+ ++SGS D TLK+WD+R++ +K G + +++ Sbjct: 399 RLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSKVCIKTVFAGSSCNDIVCT 458 Query: 184 DWSPDGEKVVSGGKDRALKLW 122 + + V+SG D+ ++ W Sbjct: 459 E-----QCVMSGHFDKKIRFW 474 Score = 47.8 bits (112), Expect = 2e-05 Identities = 40/142 (28%), Positives = 64/142 (45%), Gaps = 4/142 (2%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SGS D T+ LW+ K G N + + Q + S FDK ++ W+ I + Sbjct: 425 SGSHDRTLKLWDLRSKVCIKTVFAGSS--CNDIVCTE--QCVMSGHFDKKIRFWD-IRSE 479 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQ--DLPGH--ADEVYA 188 + + + + + + LLS S+D LKV D+R +KQ PG + Sbjct: 480 SIVREMELLGKITALDLNPERTELLSCSRDDLLKVIDLRTNAIKQTFSAPGFKCGSDWTR 539 Query: 187 VDWSPDGEKVVSGGKDRALKLW 122 V +SPDG V +G + +L +W Sbjct: 540 VVFSPDGSYVAAGSAEGSLYIW 561 Score = 42.0 bits (97), Expect = 0.001 Identities = 22/70 (31%), Positives = 37/70 (52%), Gaps = 1/70 (1%) Frame = -2 Query: 328 ADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPG-HADEVYAVDWSPDGEKVVS 152 +D ++ +S D + +GS + +L +W + K+++ L H+ + AV WSP G VVS Sbjct: 535 SDWTRVVFSPDGSYVAAGSAEGSLYIWSVLTGKVEKVLSKQHSSSINAVAWSPSGSHVVS 594 Query: 151 GGKDRALKLW 122 K LW Sbjct: 595 VDKGCKAVLW 604 Score = 40.4 bits (93), Expect = 0.003 Identities = 19/65 (29%), Positives = 35/65 (53%), Gaps = 1/65 (1%) Frame = -2 Query: 439 VYFSPDGQWLASASFDKSVKLWNGITGKFVTAF-RGHVADVYQISWSADSRLLLSGSKDS 263 V FSPDG ++A+ S + S+ +W+ +TGK + H + + ++WS ++S K Sbjct: 540 VVFSPDGSYVAAGSAEGSLYIWSVLTGKVEKVLSKQHSSSINAVAWSPSGSHVVSVDKGC 599 Query: 262 TLKVW 248 +W Sbjct: 600 KAVLW 604 Score = 30.0 bits (66), Expect = 4.3 Identities = 14/54 (25%), Positives = 23/54 (42%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLW 374 +GS + ++++W K K H +N V +SP G + S LW Sbjct: 551 AGSAEGSLYIWSVLTGKVEKVLSKQHSSSINAVAWSPSGSHVVSVDKGCKAVLW 604
>UTP13_YEAST (Q05946) U3 small nucleolar RNA-associated protein 13 (U3| snoRNA-associated protein 13) Length = 817 Score = 72.4 bits (176), Expect = 7e-13 Identities = 40/147 (27%), Positives = 73/147 (49%), Gaps = 9/147 (6%) Frame = -2 Query: 535 SGSDDFTMFLW---EPTIS------KQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSV 383 + S+D T+ W +PT S K + H+K +N + SP+ A+AS+DK+ Sbjct: 456 TASNDLTIKKWIIPKPTASMDVQIIKVSEYTRHAHEKDINALSVSPNDSIFATASYDKTC 515 Query: 382 KLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHA 203 K+WN G+ H ++ +S+ +LL + S D T+K+W + + + L GH Sbjct: 516 KIWNLENGELEATLANHKRGLWDVSFCQYDKLLATSSGDKTVKIWSLDTFSVMKTLEGHT 575 Query: 202 DEVYAVDWSPDGEKVVSGGKDRALKLW 122 + V + ++++S G D +K+W Sbjct: 576 NAVQRCSFINKQKQLISCGADGLIKIW 602 Score = 64.3 bits (155), Expect = 2e-10 Identities = 37/138 (26%), Positives = 69/138 (50%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 + S D T +W + + +A + H++ + V F + LA++S DK+VK+W+ T Sbjct: 508 TASYDKTCKIWNLE-NGELEATLANHKRGLWDVSFCQYDKLLATSSGDKTVKIWSLDTFS 566 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 + GH V + S+ + L+S D +K+WD + + + L GH + ++A+ Sbjct: 567 VMKTLEGHTNAVQRCSFINKQKQLISCGADGLIKIWDCSSGECLKTLDGHNNRLWALSTM 626 Query: 175 PDGEKVVSGGKDRALKLW 122 DG+ +VS D + W Sbjct: 627 NDGDMIVSADADGVFQFW 644 Score = 45.1 bits (105), Expect = 1e-04 Identities = 32/133 (24%), Positives = 53/133 (39%), Gaps = 19/133 (14%) Frame = -2 Query: 463 GHQKVVNHVYFSPDGQWLASASFDKSVKLW----NGITGKFVTAFRGHVADVYQISW--- 305 GH+ ++N + + DG W+A+AS D + +W N + GH A V + Sbjct: 386 GHEDLLNSLDATEDGLWIATASKDNTAIVWRYNENSCKFDIYAKYIGHSAAVTAVGLPNI 445 Query: 304 --SADSRLLLSGSKDSTLKVWDIRARKLKQDLP----------GHADEVYAVDWSPDGEK 161 LL+ S D T+K W I D+ H ++ A+ SP+ Sbjct: 446 VSKGYPEFLLTASNDLTIKKWIIPKPTASMDVQIIKVSEYTRHAHEKDINALSVSPNDSI 505 Query: 160 VVSGGKDRALKLW 122 + D+ K+W Sbjct: 506 FATASYDKTCKIW 518 Score = 38.5 bits (88), Expect = 0.012 Identities = 36/163 (22%), Positives = 64/163 (39%), Gaps = 51/163 (31%) Frame = -2 Query: 457 QKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVT----------------------- 347 ++ + + +PDGQ+L S + +K+++ TGK V Sbjct: 61 EQEITALKLTPDGQYLTYVSQAQLLKIFHLKTGKVVRSMKISSPSYILDADSTSTLLAVG 120 Query: 346 ------------------AFRGHVADVYQISW----SADSRLLLSGSKDSTLKVWDIRAR 233 +F+GH + + + ++ LL SG + +KVWD+ R Sbjct: 121 GTDGSIIVVDIENGYITHSFKGHGGTISSLKFYGQLNSKIWLLASGDTNGMVKVWDLVKR 180 Query: 232 KLKQDLPGHADEVYAVD--WSPDGEK----VVSGGKDRALKLW 122 K L H V +D PD ++ ++SGG+D + LW Sbjct: 181 KCLHTLQEHTSAVRGLDIIEVPDNDEPSLNLLSGGRDDIINLW 223 Score = 31.6 bits (70), Expect = 1.5 Identities = 18/67 (26%), Positives = 34/67 (50%), Gaps = 6/67 (8%) Frame = -2 Query: 412 LASASFDKSVKLWNGITGKFVTAFRGHVA-----DVYQISWSADSRL-LLSGSKDSTLKV 251 LAS + VK+W+ + K + + H + D+ ++ + + L LLSG +D + + Sbjct: 163 LASGDTNGMVKVWDLVKRKCLHTLQEHTSAVRGLDIIEVPDNDEPSLNLLSGGRDDIINL 222 Query: 250 WDIRARK 230 WD +K Sbjct: 223 WDFNMKK 229
>WDR1_XENLA (Q9W7F2) WD-repeat protein 1 (Actin-interacting protein 1) (XAIP1)| Length = 608 Score = 72.4 bits (176), Expect = 7e-13 Identities = 45/104 (43%), Positives = 57/104 (54%), Gaps = 4/104 (3%) Frame = -2 Query: 535 SGSDD-FTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITG 359 +GSDD FL P K M+ H + VN V FSPDG LASA D + L++G TG Sbjct: 164 TGSDDNCCAFLEGPPFKF--KFTMSDHSRFVNCVRFSPDGSKLASAGADGQIFLYDGKTG 221 Query: 358 KFVTAFRG---HVADVYQISWSADSRLLLSGSKDSTLKVWDIRA 236 + V + G H +Y +SWS D LLS S D T K+WD+ A Sbjct: 222 EKVCSLGGSKAHDGGIYAVSWSPDGTQLLSASGDKTTKIWDVAA 265 Score = 34.3 bits (77), Expect = 0.23 Identities = 17/40 (42%), Positives = 22/40 (55%) Frame = -2 Query: 460 HQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAF 341 H + V +SPDG L SAS DK+ K+W+ VT F Sbjct: 233 HDGGIYAVSWSPDGTQLLSASGDKTTKIWDVAANSAVTTF 272
>TIPD_DICDI (O15736) Protein tipD| Length = 612 Score = 72.4 bits (176), Expect = 7e-13 Identities = 38/131 (29%), Positives = 68/131 (51%) Frame = -2 Query: 514 MFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRG 335 +F E + + K R TGH + + F+ G LA+ DK VK+W+ I+G+ + G Sbjct: 305 VFSSEAMLPSKAKKRWTGHNSEIYCMAFNSIGNLLATGGGDKCVKVWDVISGQQKSTLLG 364 Query: 334 HVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVV 155 + +S+S + +L S D++ ++W+ + + L GH +VY + + +VV Sbjct: 365 ASQSIVSVSFSPNDESILGTSNDNSARLWNTELGRSRHTLTGHIGKVYTGKFI-NSNRVV 423 Query: 154 SGGKDRALKLW 122 +G DR +KLW Sbjct: 424 TGSHDRTIKLW 434 Score = 59.3 bits (142), Expect = 7e-09 Identities = 37/138 (26%), Positives = 67/138 (48%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 +G D + +W+ IS Q K+ + G + + V FSP+ + + S D S +LWN G+ Sbjct: 341 TGGGDKCVKVWD-VISGQQKSTLLGASQSIVSVSFSPNDESILGTSNDNSARLWNTELGR 399 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 GH+ VY + +R++ +GS D T+K+WD++ + + + V Sbjct: 400 SRHTLTGHIGKVYTGKFINSNRVV-TGSHDRTIKLWDLQKGYCTRTIFCFSSCNDLVILG 458 Query: 175 PDGEKVVSGGKDRALKLW 122 G + SG D +++ W Sbjct: 459 GSGTHLASGHVDHSVRFW 476 Score = 47.8 bits (112), Expect = 2e-05 Identities = 42/145 (28%), Positives = 62/145 (42%), Gaps = 7/145 (4%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNH-VYFSPDGQWLASASFDKSVKLWNGITG 359 +GS D T+ LW+ + K R N V G LAS D SV+ W+ G Sbjct: 424 TGSHDRTIKLWD--LQKGYCTRTIFCFSSCNDLVILGGSGTHLASGHVDHSVRFWDSNAG 481 Query: 358 KFVTAFRG-HVADVYQISWS-ADSRLLLSGSKDSTLKVWDIRA----RKLKQDLPGHADE 197 + H + I+ S ++ +L+ S+D TLK+ DIR R K + Sbjct: 482 EPTQVLSSIHEGQITSITNSPTNTNQILTNSRDHTLKIIDIRTFDTIRTFKDPEYRNGLN 541 Query: 196 VYAVDWSPDGEKVVSGGKDRALKLW 122 WSPDG + SG D ++ +W Sbjct: 542 WTKASWSPDGRYIASGSIDGSICIW 566 Score = 46.2 bits (108), Expect = 6e-05 Identities = 23/66 (34%), Positives = 37/66 (56%), Gaps = 3/66 (4%) Frame = -2 Query: 433 FSPDGQWLASASFDKSVKLW---NGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDS 263 +SPDG+++AS S D S+ +W NG T K +T + + V SWS + + +S KD Sbjct: 547 WSPDGRYIASGSIDGSICIWDATNGKTVKVLTKVHNNGSSVCCCSWSPLANIFISADKDK 606 Query: 262 TLKVWD 245 + W+ Sbjct: 607 NIIQWE 612 Score = 43.5 bits (101), Expect = 4e-04 Identities = 32/146 (21%), Positives = 63/146 (43%), Gaps = 8/146 (5%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDG-QWLASASFDKSVKLWNGITG 359 SG D ++ W+ + + + H+ + + SP + + S D ++K+ + T Sbjct: 466 SGHVDHSVRFWDSNAGEPTQVLSSIHEGQITSITNSPTNTNQILTNSRDHTLKIIDIRTF 525 Query: 358 KFVTAFRG----HVADVYQISWSADSRLLLSGSKDSTLKVWDI---RARKLKQDLPGHAD 200 + F+ + + + SWS D R + SGS D ++ +WD + K+ + + Sbjct: 526 DTIRTFKDPEYRNGLNWTKASWSPDGRYIASGSIDGSICIWDATNGKTVKVLTKVHNNGS 585 Query: 199 EVYAVDWSPDGEKVVSGGKDRALKLW 122 V WSP +S KD+ + W Sbjct: 586 SVCCCSWSPLANIFISADKDKNIIQW 611
>CAF1_DROME (Q24572) Probable histone-binding protein Caf1 (Chromatin assembly| factor 1 p55 subunit) (CAF-1 p55 subunit) (dCAF-1) (Nucleosome remodeling factor 55 kDa subunit) (NURF-55) Length = 430 Score = 72.4 bits (176), Expect = 7e-13 Identities = 53/153 (34%), Positives = 76/153 (49%), Gaps = 15/153 (9%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKAR--------MTGHQKVVNHVYFSPDGQWL-ASASFDKSV 383 S SDD T+ LW+ I+ PK TGH VV V + + L S + D+ + Sbjct: 199 SASDDHTICLWD--INATPKEHRVIDAKNIFTGHTAVVEDVAWHLLHESLFGSVADDQKL 256 Query: 382 KLW---NGITGKFVTAFRGHVADVYQISWSADSRLLLS-GSKDSTLKVWDIRARKLK-QD 218 +W N T K H A+V +S++ S +L+ GS D T+ +WD+R KLK Sbjct: 257 MIWDTRNNNTSKPSHTVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHS 316 Query: 217 LPGHADEVYAVDWSPDGEKVV-SGGKDRALKLW 122 H DE++ V WSP E ++ S G DR L +W Sbjct: 317 FESHKDEIFQVQWSPHNETILASSGTDRRLHVW 349 Score = 36.2 bits (82), Expect = 0.059 Identities = 27/82 (32%), Positives = 37/82 (45%), Gaps = 9/82 (10%) Frame = -2 Query: 340 RGHVADVYQISWSAD-SRLLLSGSKDSTLKVWDIRAR-------KLKQDLPGHADEVYAV 185 RGH + Y +SW+ + + LLS S D T+ +WDI A K GH V V Sbjct: 178 RGHQKEGYGLSWNPNLNGYLLSASDDHTICLWDINATPKEHRVIDAKNIFTGHTAVVEDV 237 Query: 184 DWSPDGEKVV-SGGKDRALKLW 122 W E + S D+ L +W Sbjct: 238 AWHLLHESLFGSVADDQKLMIW 259
>RBBP7_RAT (Q71UF4) Histone-binding protein RBBP7 (Retinoblastoma-binding| protein 7) (RBBP-7) Length = 425 Score = 72.0 bits (175), Expect = 1e-12 Identities = 53/151 (35%), Positives = 76/151 (50%), Gaps = 13/151 (8%) Frame = -2 Query: 535 SGSDDFTMFLWE----PTISK--QPKARMTGHQKVVNHVYFSPDGQWL-ASASFDKSVKL 377 S SDD T+ LW+ P K KA TGH VV V + + L S + D+ + + Sbjct: 194 SASDDHTVCLWDINAGPKEGKIVDAKAIFTGHSAVVEDVAWHLLHESLFGSVADDQKLMI 253 Query: 376 WN---GITGKFVTAFRGHVADVYQISWSADSRLLLS-GSKDSTLKVWDIRARKLK-QDLP 212 W+ T K H A+V +S++ S +L+ GS D T+ +WD+R KLK Sbjct: 254 WDTRSNTTSKPSHLVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHTFE 313 Query: 211 GHADEVYAVDWSPDGEKVV-SGGKDRALKLW 122 H DE++ V WSP E ++ S G DR L +W Sbjct: 314 SHKDEIFQVHWSPHNETILASSGTDRRLNVW 344 Score = 36.6 bits (83), Expect = 0.045 Identities = 28/82 (34%), Positives = 39/82 (47%), Gaps = 9/82 (10%) Frame = -2 Query: 340 RGHVADVYQISWSAD-SRLLLSGSKDSTLKVWDIRAR-------KLKQDLPGHADEVYAV 185 RGH + Y +SW+++ S LLS S D T+ +WDI A K GH+ V V Sbjct: 173 RGHQKEGYGLSWNSNLSGHLLSASDDHTVCLWDINAGPKEGKIVDAKAIFTGHSAVVEDV 232 Query: 184 DWSPDGEKVV-SGGKDRALKLW 122 W E + S D+ L +W Sbjct: 233 AWHLLHESLFGSVADDQKLMIW 254
>RBBP7_MOUSE (Q60973) Histone-binding protein RBBP7 (Retinoblastoma-binding| protein 7) (RBBP-7) (Retinoblastoma-binding protein p46) (Histone acetyltransferase type B subunit 2) Length = 425 Score = 72.0 bits (175), Expect = 1e-12 Identities = 53/151 (35%), Positives = 76/151 (50%), Gaps = 13/151 (8%) Frame = -2 Query: 535 SGSDDFTMFLWE----PTISK--QPKARMTGHQKVVNHVYFSPDGQWL-ASASFDKSVKL 377 S SDD T+ LW+ P K KA TGH VV V + + L S + D+ + + Sbjct: 194 SASDDHTVCLWDINAGPKEGKIVDAKAIFTGHSAVVEDVAWHLLHESLFGSVADDQKLMI 253 Query: 376 WN---GITGKFVTAFRGHVADVYQISWSADSRLLLS-GSKDSTLKVWDIRARKLK-QDLP 212 W+ T K H A+V +S++ S +L+ GS D T+ +WD+R KLK Sbjct: 254 WDTRSNTTSKPSHLVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHTFE 313 Query: 211 GHADEVYAVDWSPDGEKVV-SGGKDRALKLW 122 H DE++ V WSP E ++ S G DR L +W Sbjct: 314 SHKDEIFQVHWSPHNETILASSGTDRRLNVW 344 Score = 36.6 bits (83), Expect = 0.045 Identities = 28/82 (34%), Positives = 39/82 (47%), Gaps = 9/82 (10%) Frame = -2 Query: 340 RGHVADVYQISWSAD-SRLLLSGSKDSTLKVWDIRAR-------KLKQDLPGHADEVYAV 185 RGH + Y +SW+++ S LLS S D T+ +WDI A K GH+ V V Sbjct: 173 RGHQKEGYGLSWNSNLSGHLLSASDDHTVCLWDINAGPKEGKIVDAKAIFTGHSAVVEDV 232 Query: 184 DWSPDGEKVV-SGGKDRALKLW 122 W E + S D+ L +W Sbjct: 233 AWHLLHESLFGSVADDQKLMIW 254
>RBBP7_MACFA (Q4R304) Histone-binding protein RBBP7 (Retinoblastoma-binding| protein 7) (RBBP-7) Length = 425 Score = 72.0 bits (175), Expect = 1e-12 Identities = 53/151 (35%), Positives = 76/151 (50%), Gaps = 13/151 (8%) Frame = -2 Query: 535 SGSDDFTMFLWE----PTISK--QPKARMTGHQKVVNHVYFSPDGQWL-ASASFDKSVKL 377 S SDD T+ LW+ P K KA TGH VV V + + L S + D+ + + Sbjct: 194 SASDDHTVCLWDINAGPKEGKIVDAKAIFTGHSAVVEDVAWHLLHESLFGSVADDQKLMI 253 Query: 376 WN---GITGKFVTAFRGHVADVYQISWSADSRLLLS-GSKDSTLKVWDIRARKLK-QDLP 212 W+ T K H A+V +S++ S +L+ GS D T+ +WD+R KLK Sbjct: 254 WDTRSNTTSKPSHLVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHTFE 313 Query: 211 GHADEVYAVDWSPDGEKVV-SGGKDRALKLW 122 H DE++ V WSP E ++ S G DR L +W Sbjct: 314 SHKDEIFQVHWSPHNETILASSGTDRRLNVW 344 Score = 36.6 bits (83), Expect = 0.045 Identities = 28/82 (34%), Positives = 39/82 (47%), Gaps = 9/82 (10%) Frame = -2 Query: 340 RGHVADVYQISWSAD-SRLLLSGSKDSTLKVWDIRAR-------KLKQDLPGHADEVYAV 185 RGH + Y +SW+++ S LLS S D T+ +WDI A K GH+ V V Sbjct: 173 RGHQKEGYGLSWNSNLSGHLLSASDDHTVCLWDINAGPKEGKIVDAKAIFTGHSAVVEDV 232 Query: 184 DWSPDGEKVV-SGGKDRALKLW 122 W E + S D+ L +W Sbjct: 233 AWHLLHESLFGSVADDQKLMIW 254
>RBBP7_HUMAN (Q16576) Histone-binding protein RBBP7 (Retinoblastoma-binding| protein 7) (RBBP-7) (Retinoblastoma-binding protein p46) (Histone acetyltransferase type B subunit 2) Length = 425 Score = 72.0 bits (175), Expect = 1e-12 Identities = 53/151 (35%), Positives = 76/151 (50%), Gaps = 13/151 (8%) Frame = -2 Query: 535 SGSDDFTMFLWE----PTISK--QPKARMTGHQKVVNHVYFSPDGQWL-ASASFDKSVKL 377 S SDD T+ LW+ P K KA TGH VV V + + L S + D+ + + Sbjct: 194 SASDDHTVCLWDINAGPKEGKIVDAKAIFTGHSAVVEDVAWHLLHESLFGSVADDQKLMI 253 Query: 376 WN---GITGKFVTAFRGHVADVYQISWSADSRLLLS-GSKDSTLKVWDIRARKLK-QDLP 212 W+ T K H A+V +S++ S +L+ GS D T+ +WD+R KLK Sbjct: 254 WDTRSNTTSKPSHLVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHTFE 313 Query: 211 GHADEVYAVDWSPDGEKVV-SGGKDRALKLW 122 H DE++ V WSP E ++ S G DR L +W Sbjct: 314 SHKDEIFQVHWSPHNETILASSGTDRRLNVW 344 Score = 36.6 bits (83), Expect = 0.045 Identities = 28/82 (34%), Positives = 39/82 (47%), Gaps = 9/82 (10%) Frame = -2 Query: 340 RGHVADVYQISWSAD-SRLLLSGSKDSTLKVWDIRAR-------KLKQDLPGHADEVYAV 185 RGH + Y +SW+++ S LLS S D T+ +WDI A K GH+ V V Sbjct: 173 RGHQKEGYGLSWNSNLSGHLLSASDDHTVCLWDINAGPKEGKIVDAKAIFTGHSAVVEDV 232 Query: 184 DWSPDGEKVV-SGGKDRALKLW 122 W E + S D+ L +W Sbjct: 233 AWHLLHESLFGSVADDQKLMIW 254
>RBBP7_BOVIN (Q3SWX8) Histone-binding protein RBBP7 (Retinoblastoma-binding| protein 7) (RBBP-7) Length = 425 Score = 72.0 bits (175), Expect = 1e-12 Identities = 53/151 (35%), Positives = 76/151 (50%), Gaps = 13/151 (8%) Frame = -2 Query: 535 SGSDDFTMFLWE----PTISK--QPKARMTGHQKVVNHVYFSPDGQWL-ASASFDKSVKL 377 S SDD T+ LW+ P K KA TGH VV V + + L S + D+ + + Sbjct: 194 SASDDHTVCLWDINAGPKEGKIVDAKAIFTGHSAVVEDVAWHLLHESLFGSVADDQKLMI 253 Query: 376 WN---GITGKFVTAFRGHVADVYQISWSADSRLLLS-GSKDSTLKVWDIRARKLK-QDLP 212 W+ T K H A+V +S++ S +L+ GS D T+ +WD+R KLK Sbjct: 254 WDTRSNTTSKPSHLVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHTFE 313 Query: 211 GHADEVYAVDWSPDGEKVV-SGGKDRALKLW 122 H DE++ V WSP E ++ S G DR L +W Sbjct: 314 SHKDEIFQVHWSPHNETILASSGTDRRLNVW 344 Score = 36.6 bits (83), Expect = 0.045 Identities = 28/82 (34%), Positives = 39/82 (47%), Gaps = 9/82 (10%) Frame = -2 Query: 340 RGHVADVYQISWSAD-SRLLLSGSKDSTLKVWDIRAR-------KLKQDLPGHADEVYAV 185 RGH + Y +SW+++ S LLS S D T+ +WDI A K GH+ V V Sbjct: 173 RGHQKEGYGLSWNSNLSGHLLSASDDHTVCLWDINAGPKEGKIVDAKAIFTGHSAVVEDV 232 Query: 184 DWSPDGEKVV-SGGKDRALKLW 122 W E + S D+ L +W Sbjct: 233 AWHLLHESLFGSVADDQKLMIW 254
>WDR12_RAT (P61480) WD-repeat protein 12| Length = 423 Score = 72.0 bits (175), Expect = 1e-12 Identities = 52/140 (37%), Positives = 79/140 (56%), Gaps = 5/140 (3%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT-- 362 S S D T+ +W+ S K+ +TG+ KV N + +SP + LAS S D+ ++LW+ T Sbjct: 273 SASWDHTVRVWDVE-SGGLKSTLTGN-KVFNCISYSPLCKRLASGSTDRHIRLWDPRTKD 330 Query: 361 GKFVT-AFRGHVADVYQISWS-ADSRLLLSGSKDSTLKVWDIRARKLK-QDLPGHADEVY 191 G V+ + H V + WS + L+SGS D+ +K+WD R+ K DL H D+V Sbjct: 331 GSLVSLSLTSHTGWVTSVKWSPTHDQQLISGSLDNMVKLWDTRSCKAPLYDLAAHEDKVL 390 Query: 190 AVDWSPDGEKVVSGGKDRAL 131 +VDW+ G ++SGG D L Sbjct: 391 SVDWTDTG-LLLSGGADNKL 409 Score = 63.5 bits (153), Expect = 3e-10 Identities = 40/134 (29%), Positives = 73/134 (54%), Gaps = 5/134 (3%) Frame = -2 Query: 493 ISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQ 314 +++ P ++GH + ++ V +S D + SAS+D +V++W+ +G + G+ V+ Sbjct: 245 LTRTPLVTLSGHTEAISSVLWS-DADEVCSASWDHTVRVWDVESGGLKSTLTGN--KVFN 301 Query: 313 -ISWSADSRLLLSGSKDSTLKVWDIRARK---LKQDLPGHADEVYAVDWSPD-GEKVVSG 149 IS+S + L SGS D +++WD R + + L H V +V WSP ++++SG Sbjct: 302 CISYSPLCKRLASGSTDRHIRLWDPRTKDGSLVSLSLTSHTGWVTSVKWSPTHDQQLISG 361 Query: 148 GKDRALKLWMN*AC 107 D +KLW +C Sbjct: 362 SLDNMVKLWDTRSC 375 Score = 60.1 bits (144), Expect = 4e-09 Identities = 44/168 (26%), Positives = 74/168 (44%), Gaps = 30/168 (17%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARM---TGHQKVVNHVYFSPDGQWLASASFDKSVKLWN-- 371 + S D T+ LWE I + + GH V+ + G S S+DK +K+W+ Sbjct: 160 TASMDQTILLWEWNIERNKVKALHCCRGHAGSVDAIAVDSSGTKFCSGSWDKMLKIWSTV 219 Query: 370 ------------------------GITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDS 263 G+T + GH + + WS D+ + S S D Sbjct: 220 PTDEEDEIQEPTNRPRKKQKTEQLGLTRTPLVTLSGHTEAISSVLWS-DADEVCSASWDH 278 Query: 262 TLKVWDIRARKLKQDLPGHADEVY-AVDWSPDGEKVVSGGKDRALKLW 122 T++VWD+ + LK L G ++V+ + +SP +++ SG DR ++LW Sbjct: 279 TVRVWDVESGGLKSTLTG--NKVFNCISYSPLCKRLASGSTDRHIRLW 324 Score = 60.1 bits (144), Expect = 4e-09 Identities = 36/106 (33%), Positives = 56/106 (52%), Gaps = 7/106 (6%) Frame = -2 Query: 418 QWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISW---SADSRLLLSGSKDSTLKVW 248 +W+ S S+DK+ ++W+ + GK + GH V ++W + S LLL+ S D T+ +W Sbjct: 112 EWILSGSYDKTSRIWS-LEGKSIMTIVGHTDVVKDVAWVKKDSLSCLLLTASMDQTILLW 170 Query: 247 D--IRARKLK--QDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 + I K+K GHA V A+ G K SG D+ LK+W Sbjct: 171 EWNIERNKVKALHCCRGHAGSVDAIAVDSSGTKFCSGSWDKMLKIW 216
>WDR12_MOUSE (Q9JJA4) WD-repeat protein 12 (YTM1 homolog)| Length = 423 Score = 72.0 bits (175), Expect = 1e-12 Identities = 52/140 (37%), Positives = 79/140 (56%), Gaps = 5/140 (3%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT-- 362 S S D T+ +W+ S K+ +TG+ KV N + +SP + LAS S D+ ++LW+ T Sbjct: 273 SASWDHTIRVWDVE-SGGLKSTLTGN-KVFNCISYSPLCKRLASGSTDRHIRLWDPRTKD 330 Query: 361 GKFVT-AFRGHVADVYQISWS-ADSRLLLSGSKDSTLKVWDIRARKLK-QDLPGHADEVY 191 G V+ + H V + WS + L+SGS D+ +K+WD R+ K DL H D+V Sbjct: 331 GSLVSLSLTSHTGWVTSVKWSPTHEQQLISGSLDNIVKLWDTRSCKAPLYDLAAHEDKVL 390 Query: 190 AVDWSPDGEKVVSGGKDRAL 131 +VDW+ G ++SGG D L Sbjct: 391 SVDWTDTG-LLLSGGADNKL 409 Score = 65.1 bits (157), Expect = 1e-10 Identities = 40/134 (29%), Positives = 74/134 (55%), Gaps = 5/134 (3%) Frame = -2 Query: 493 ISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQ 314 +++ P ++GH + ++ V +S D + + SAS+D ++++W+ +G + G+ V+ Sbjct: 245 LTRTPLVTLSGHTEAISSVLWS-DAEEICSASWDHTIRVWDVESGGLKSTLTGN--KVFN 301 Query: 313 -ISWSADSRLLLSGSKDSTLKVWDIRARK---LKQDLPGHADEVYAVDWSPDGEK-VVSG 149 IS+S + L SGS D +++WD R + + L H V +V WSP E+ ++SG Sbjct: 302 CISYSPLCKRLASGSTDRHIRLWDPRTKDGSLVSLSLTSHTGWVTSVKWSPTHEQQLISG 361 Query: 148 GKDRALKLWMN*AC 107 D +KLW +C Sbjct: 362 SLDNIVKLWDTRSC 375 Score = 62.4 bits (150), Expect = 8e-10 Identities = 44/168 (26%), Positives = 74/168 (44%), Gaps = 30/168 (17%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARM---TGHQKVVNHVYFSPDGQWLASASFDKSVKLWN-- 371 + S D T+ LWE + K + GH V+ + G S S+DK +K+W+ Sbjct: 160 TASMDQTVLLWEWNVEKNKVKALHCCRGHAGSVDAIAVDSSGAKFCSGSWDKMLKIWSTV 219 Query: 370 ------------------------GITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDS 263 G+T + GH + + WS D+ + S S D Sbjct: 220 PTDEEDEMEEATNRPRKKQKTEQLGLTRTPLVTLSGHTEAISSVLWS-DAEEICSASWDH 278 Query: 262 TLKVWDIRARKLKQDLPGHADEVY-AVDWSPDGEKVVSGGKDRALKLW 122 T++VWD+ + LK L G ++V+ + +SP +++ SG DR ++LW Sbjct: 279 TIRVWDVESGGLKSTLTG--NKVFNCISYSPLCKRLASGSTDRHIRLW 324 Score = 60.1 bits (144), Expect = 4e-09 Identities = 35/106 (33%), Positives = 54/106 (50%), Gaps = 7/106 (6%) Frame = -2 Query: 418 QWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISW---SADSRLLLSGSKDSTLKVW 248 +W+ S S+DK+ ++W+ + GK + GH V ++W + S LLL+ S D T+ +W Sbjct: 112 EWILSGSYDKTSRIWS-LEGKSIMTIVGHTDVVKDVAWVKKDSLSCLLLTASMDQTVLLW 170 Query: 247 DIRARKLKQDL----PGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 + K K GHA V A+ G K SG D+ LK+W Sbjct: 171 EWNVEKNKVKALHCCRGHAGSVDAIAVDSSGAKFCSGSWDKMLKIW 216
>GBB_LOLFO (P23232) Guanine nucleotide-binding protein beta subunit| Length = 341 Score = 72.0 bits (175), Expect = 1e-12 Identities = 38/116 (32%), Positives = 63/116 (54%) Frame = -2 Query: 469 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 290 + GH ++ F D Q + ++S D + LWN TG +T+F GH DV +S + D R Sbjct: 140 LPGHTGYLSCCRFIDDNQ-IVTSSGDMTCALWNIETGNQITSFGGHTGDVMSLSLAPDMR 198 Query: 289 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 +SG+ D++ K++DIR KQ GH ++ A+ + P+G +G D +L+ Sbjct: 199 TFVSGACDASAKLFDIRDGICKQTFTGHESDINAITYFPNGFAFATGSDDATCRLF 254 Score = 58.2 bits (139), Expect = 1e-08 Identities = 33/121 (27%), Positives = 59/121 (48%), Gaps = 2/121 (1%) Frame = -2 Query: 478 KARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGH--VADVYQISW 305 K TGH+ +N + + P+G A+ S D + +L++ + + + + + +++ Sbjct: 220 KQTFTGHESDINAITYFPNGFAFATGSDDATCRLFDIRADQEIGMYSHDNIICGITSVAF 279 Query: 304 SADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKL 125 S RLLL G D VWD+ ++ L GH + V + + DG V +G D LK+ Sbjct: 280 SKSGRLLLGGYDDFNCNVWDVLKQERAGVLAGHDNRVSCLGVTEDGMAVATGSWDSFLKI 339 Query: 124 W 122 W Sbjct: 340 W 340 Score = 52.0 bits (123), Expect = 1e-06 Identities = 25/73 (34%), Positives = 38/73 (52%) Frame = -2 Query: 340 RGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEK 161 RGH+A +Y + W++DSR L+S S+D L VWD +P + V ++P G Sbjct: 53 RGHLAKIYAMHWASDSRNLVSASQDGKLIVWDGYTTNKVHAIPLRSSWVMTCAYAPSGNY 112 Query: 160 VVSGGKDRALKLW 122 V GG D ++ Sbjct: 113 VACGGLDNICSIY 125 Score = 45.1 bits (105), Expect = 1e-04 Identities = 33/133 (24%), Positives = 60/133 (45%), Gaps = 6/133 (4%) Frame = -2 Query: 502 EPTISKQPKARMT--GHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHV 329 EP Q + R T GH + ++++ D + L SAS D + +W+G T V A Sbjct: 39 EPVGRIQMRTRRTLRGHLAKIYAMHWASDSRNLVSASQDGKLIVWDGYTTNKVHAIPLRS 98 Query: 328 ADVYQISWSADSRLLLSGSKDSTLKVWDIRAR----KLKQDLPGHADEVYAVDWSPDGEK 161 + V +++ + G D+ ++ ++ R ++ ++LPGH + + D + Sbjct: 99 SWVMTCAYAPSGNYVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFIDDNQI 158 Query: 160 VVSGGKDRALKLW 122 V S G D LW Sbjct: 159 VTSSG-DMTCALW 170 Score = 38.1 bits (87), Expect = 0.016 Identities = 27/100 (27%), Positives = 45/100 (45%), Gaps = 3/100 (3%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVV---NHVYFSPDGQWLASASFDKSVKLWNGI 365 +GSDD T L++ I + M H ++ V FS G+ L D + +W+ + Sbjct: 244 TGSDDATCRLFD--IRADQEIGMYSHDNIICGITSVAFSKSGRLLLGGYDDFNCNVWDVL 301 Query: 364 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD 245 + GH V + + D + +GS DS LK+W+ Sbjct: 302 KQERAGVLAGHDNRVSCLGVTEDGMAVATGSWDSFLKIWN 341
>GBB4_HUMAN (Q9HAV0) Guanine nucleotide-binding protein beta subunit 4| (Transducin beta chain 4) Length = 339 Score = 72.0 bits (175), Expect = 1e-12 Identities = 38/116 (32%), Positives = 61/116 (52%) Frame = -2 Query: 469 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 290 + GH ++ F D Q + ++S D + LW+ T + T F GH DV +S S D R Sbjct: 138 LPGHTGYLSCCRFLDDSQ-IVTSSGDTTCALWDIETAQQTTTFTGHSGDVMSLSLSPDMR 196 Query: 289 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 +SG+ D++ K+WDIR +Q GH ++ AV + P+G +G D +L+ Sbjct: 197 TFVSGACDASSKLWDIRDGMCRQSFTGHVSDINAVSFFPNGYAFATGSDDATCRLF 252 Score = 60.5 bits (145), Expect = 3e-09 Identities = 41/143 (28%), Positives = 72/143 (50%), Gaps = 5/143 (3%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 + S D T LW+ ++Q TGH V + SPD + S + D S KLW+ G Sbjct: 158 TSSGDTTCALWDIETAQQTTT-FTGHSGDVMSLSLSPDMRTFVSGACDASSKLWDIRDGM 216 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADE-----VY 191 +F GHV+D+ +S+ + +GS D+T +++D+RA Q+L ++ + + Sbjct: 217 CRQSFTGHVSDINAVSFFPNGYAFATGSDDATCRLFDLRA---DQELLLYSHDNIICGIT 273 Query: 190 AVDWSPDGEKVVSGGKDRALKLW 122 +V +S G +++G D +W Sbjct: 274 SVAFSKSGRLLLAGYDDFNCNVW 296 Score = 53.9 bits (128), Expect = 3e-07 Identities = 25/73 (34%), Positives = 37/73 (50%) Frame = -2 Query: 340 RGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEK 161 RGH+A +Y + W DSRLL+S S+D L +WD +P + V ++P G Sbjct: 51 RGHLAKIYAMHWGYDSRLLVSASQDGKLIIWDSYTTNKMHAIPLRSSWVMTCAYAPSGNY 110 Query: 160 VVSGGKDRALKLW 122 V GG D ++ Sbjct: 111 VACGGLDNICSIY 123 Score = 41.6 bits (96), Expect = 0.001 Identities = 27/128 (21%), Positives = 57/128 (44%), Gaps = 4/128 (3%) Frame = -2 Query: 493 ISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQ 314 I + + + GH + +++ D + L SAS D + +W+ T + A + V Sbjct: 42 IQMRTRRTLRGHLAKIYAMHWGYDSRLLVSASQDGKLIIWDSYTTNKMHAIPLRSSWVMT 101 Query: 313 ISWSADSRLLLSGSKDSTLKVWDIRAR----KLKQDLPGHADEVYAVDWSPDGEKVVSGG 146 +++ + G D+ +++++ R ++ ++LPGH + + D + V S G Sbjct: 102 CAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELPGHTGYLSCCRFLDDSQIVTSSG 161 Query: 145 KDRALKLW 122 D LW Sbjct: 162 -DTTCALW 168 Score = 37.7 bits (86), Expect = 0.020 Identities = 25/100 (25%), Positives = 46/100 (46%), Gaps = 3/100 (3%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVV---NHVYFSPDGQWLASASFDKSVKLWNGI 365 +GSDD T L++ + + + H ++ V FS G+ L + D + +W+ + Sbjct: 242 TGSDDATCRLFD--LRADQELLLYSHDNIICGITSVAFSKSGRLLLAGYDDFNCNVWDTL 299 Query: 364 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD 245 G GH V + + D + +GS DS L++W+ Sbjct: 300 KGDRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLRIWN 339
>WDR1_HUMAN (O75083) WD-repeat protein 1 (Actin-interacting protein 1) (AIP1)| (NORI-1) Length = 605 Score = 71.6 bits (174), Expect = 1e-12 Identities = 44/111 (39%), Positives = 58/111 (52%), Gaps = 3/111 (2%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 +GSDD +E K K + H + VN V FSPDG A+AS D + +++G TG+ Sbjct: 163 TGSDDNCAAFFEGPPFKF-KFTIGDHSRFVNCVRFSPDGNRFATASADGQIYIYDGKTGE 221 Query: 355 FVTAFRG---HVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLP 212 V A G H +Y ISWS DS LLS S D T K+WD+ + P Sbjct: 222 KVCALGGSKAHDGGIYAISWSPDSTHLLSASGDKTSKIWDVSVNSVVSTFP 272 Score = 57.4 bits (137), Expect = 2e-08 Identities = 38/135 (28%), Positives = 59/135 (43%), Gaps = 4/135 (2%) Frame = -2 Query: 514 MFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQW-LASASFDKSVKLWNGITGKFVTAFR 338 +FLW+ S +TGH KV+N V + LA+ S D + G KF Sbjct: 129 VFLWD---SGSSVGEITGHNKVINSVDIKQSRPYRLATGSDDNCAAFFEGPPFKFKFTIG 185 Query: 337 GHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPG---HADEVYAVDWSPDG 167 H V + +S D + S D + ++D + + L G H +YA+ WSPD Sbjct: 186 DHSRFVNCVRFSPDGNRFATASADGQIYIYDGKTGEKVCALGGSKAHDGGIYAISWSPDS 245 Query: 166 EKVVSGGKDRALKLW 122 ++S D+ K+W Sbjct: 246 THLLSASGDKTSKIW 260 Score = 38.5 bits (88), Expect = 0.012 Identities = 30/112 (26%), Positives = 49/112 (43%), Gaps = 3/112 (2%) Frame = -2 Query: 448 VNHVYFSPDGQWLASASFDKSVKLWNGITGKFVT-AFRGHVADVYQISWSADSRLLLSGS 272 V V +S DG +LA K V +++ G F GH A + ++WS D+ SG Sbjct: 491 VTDVAYSHDGAFLAVCDASKVVTVFSVADGYSENNVFYGHHAKIVCLAWSPDNEHFASGG 550 Query: 271 KDSTLKVWDIR--ARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 D + VW + ++K V ++ W D +V+ D ++K W Sbjct: 551 MDMMVYVWTLSDPETRVKIQDAHRLHHVSSLAWL-DEHTLVTTSHDASVKEW 601 Score = 38.5 bits (88), Expect = 0.012 Identities = 31/109 (28%), Positives = 51/109 (46%), Gaps = 7/109 (6%) Frame = -2 Query: 427 PDGQWLASASFDKSVKLWN--GIT----GKFVTAFRGHVADVYQISWSADSRLLLSGSKD 266 P G +A D +V+L++ G T GK + A +G V DV ++S D L Sbjct: 454 PGGDTVAIGGVDGNVRLYSILGTTLKDEGKLLEA-KGPVTDV---AYSHDGAFLAVCDAS 509 Query: 265 STLKVWDIRARKLKQDL-PGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 + V+ + + ++ GH ++ + WSPD E SGG D + +W Sbjct: 510 KVVTVFSVADGYSENNVFYGHHAKIVCLAWSPDNEHFASGGMDMMVYVW 558 Score = 31.6 bits (70), Expect = 1.5 Identities = 23/78 (29%), Positives = 35/78 (44%), Gaps = 4/78 (5%) Frame = -2 Query: 463 GHQKVVNHVYFSPDGQWLASASFDKSVKLWN----GITGKFVTAFRGHVADVYQISWSAD 296 GH + + +SPD + AS D V +W K A R H V ++W D Sbjct: 529 GHHAKIVCLAWSPDNEHFASGGMDMMVYVWTLSDPETRVKIQDAHRLH--HVSSLAW-LD 585 Query: 295 SRLLLSGSKDSTLKVWDI 242 L++ S D+++K W I Sbjct: 586 EHTLVTTSHDASVKEWTI 603
>CAF1B_MOUSE (Q9D0N7) Chromatin assembly factor 1 subunit B (CAF-1 subunit B)| (Chromatin assembly factor I p60 subunit) (CAF-I 60 kDa subunit) (CAF-Ip60) Length = 572 Score = 71.6 bits (174), Expect = 1e-12 Identities = 42/139 (30%), Positives = 60/139 (43%), Gaps = 21/139 (15%) Frame = -2 Query: 475 ARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK-------------------- 356 + + H K VN V FSP G+ LAS D + LW K Sbjct: 60 SNLARHTKAVNVVRFSPTGEILASGGDDAVILLWKMNDSKEPEQIAFQDEEEAQLNKENW 119 Query: 355 -FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDW 179 V RGH+ DVY I W+ D L+ S S D+T+ +WD+ + H V V W Sbjct: 120 TVVKTLRGHLEDVYDICWATDGNLMTSASVDNTVIIWDVSKGQKISIFNEHKSYVQGVTW 179 Query: 178 SPDGEKVVSGGKDRALKLW 122 P G+ + + DR L+++ Sbjct: 180 DPLGQYIATLSCDRVLRIY 198 Score = 49.7 bits (117), Expect = 5e-06 Identities = 28/123 (22%), Positives = 58/123 (47%), Gaps = 20/123 (16%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKA--------------------RMTGHQKVVNHVYFSPDGQ 416 SG DD + LW+ SK+P+ + GH + V + ++ DG Sbjct: 83 SGGDDAVILLWKMNDSKEPEQIAFQDEEEAQLNKENWTVVKTLRGHLEDVYDICWATDGN 142 Query: 415 WLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRA 236 + SAS D +V +W+ G+ ++ F H + V ++W + + + S D L++++ + Sbjct: 143 LMTSASVDNTVIIWDVSKGQKISIFNEHKSYVQGVTWDPLGQYIATLSCDRVLRIYNTQK 202 Query: 235 RKL 227 +++ Sbjct: 203 KRV 205
>ATG16_XENTR (Q5I0B9) Autophagy-related protein 16 (APG16-like 1)| Length = 537 Score = 71.6 bits (174), Expect = 1e-12 Identities = 39/115 (33%), Positives = 59/115 (51%), Gaps = 2/115 (1%) Frame = -2 Query: 460 HQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVT--AFRGHVADVYQISWSADSRL 287 H VN V FSP + LA+ D+ VKLW+ I K + G A + I + + Sbjct: 251 HDGEVNAVRFSPGSRLLATGGMDRRVKLWDVIGNKCEAKGSLTGSNAGITSIEFDSAGSY 310 Query: 286 LLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 LL+ S D ++W + +L+ L GH+ +V + + D ++VSG DR LKLW Sbjct: 311 LLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLW 365 Score = 54.3 bits (129), Expect = 2e-07 Identities = 36/141 (25%), Positives = 69/141 (48%), Gaps = 3/141 (2%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISK-QPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITG 359 +G D + LW+ +K + K +TG + + F G +L +AS D + ++W Sbjct: 269 TGGMDRRVKLWDVIGNKCEAKGSLTGSNAGITSIEFDSAGSYLLAASNDFASRIWTVDDY 328 Query: 358 KFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARK-LKQDLPGHA-DEVYAV 185 + GH V + D+ ++SGS D TLK+WD+R++ +K G + +++ Sbjct: 329 RLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSKVCIKTVFAGSSCNDIVCT 388 Query: 184 DWSPDGEKVVSGGKDRALKLW 122 + + V+SG D+ ++ W Sbjct: 389 E-----QCVMSGHFDKKIRFW 404 Score = 43.5 bits (101), Expect = 4e-04 Identities = 33/138 (23%), Positives = 66/138 (47%), Gaps = 1/138 (0%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 + S+DF +W + + +TGH V F D + S S D+++KLW+ + Sbjct: 313 AASNDFASRIWTVD-DYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSKV 371 Query: 355 FV-TAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDW 179 + T F G + + + ++SG D ++ WDIR + ++L + A+D Sbjct: 372 CIKTVFAGSSCNDIVCT----EQCVMSGHFDKKIRFWDIRTECIVRELELQG-RITALDL 426 Query: 178 SPDGEKVVSGGKDRALKL 125 +P+ +++S +D +K+ Sbjct: 427 NPERTQLLSCSRDDLIKI 444 Score = 42.0 bits (97), Expect = 0.001 Identities = 20/65 (30%), Positives = 36/65 (55%), Gaps = 1/65 (1%) Frame = -2 Query: 439 VYFSPDGQWLASASFDKSVKLWNGITGKFVTAF-RGHVADVYQISWSADSRLLLSGSKDS 263 V FSPDG ++++ S + ++ WN +TGK F + H + + ++WS ++S K S Sbjct: 470 VIFSPDGSYVSAGSAEGTLYFWNVLTGKVERMFSKQHSSSINAVAWSPSGTHVVSVDKGS 529 Query: 262 TLKVW 248 +W Sbjct: 530 RGVLW 534 Score = 40.8 bits (94), Expect = 0.002 Identities = 30/108 (27%), Positives = 49/108 (45%), Gaps = 5/108 (4%) Frame = -2 Query: 430 SPDGQWLASASFDKSVKLW----NGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDS 263 +P+ L S S D +K+ N + F +D ++ +S D + +GS + Sbjct: 427 NPERTQLLSCSRDDLIKITDLRANAVQQTFSAPGFKCGSDWTRVIFSPDGSYVSAGSAEG 486 Query: 262 TLKVWDIRARKLKQDLPG-HADEVYAVDWSPDGEKVVSGGKDRALKLW 122 TL W++ K+++ H+ + AV WSP G VVS K LW Sbjct: 487 TLYFWNVLTGKVERMFSKQHSSSINAVAWSPSGTHVVSVDKGSRGVLW 534
>MORG1_HUMAN (Q9BRX9) Mitogen-activated protein kinase organizer 1 (MAPK| organizer 1) Length = 315 Score = 71.6 bits (174), Expect = 1e-12 Identities = 33/112 (29%), Positives = 60/112 (53%) Frame = -2 Query: 457 QKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLS 278 Q V V F+ DG + + DK++KLWN + G + + GH +V + S D+ L S Sbjct: 25 QGAVRAVRFNVDGNYCLTCGSDKTLKLWNPLRGTLLRTYSGHGYEVLDAAGSFDNSSLCS 84 Query: 277 GSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 G D + +WD+ + ++ + GHA +V V ++ + ++SG D +++ W Sbjct: 85 GGGDKAVVLWDVASGQVVRKFRGHAGKVNTVQFNEEATVILSGSIDSSIRCW 136 Score = 61.2 bits (147), Expect = 2e-09 Identities = 34/98 (34%), Positives = 53/98 (54%) Frame = -2 Query: 523 DFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTA 344 D T+ LW P + +GH V S D L S DK+V LW+ +G+ V Sbjct: 46 DKTLKLWNPLRGTLLRT-YSGHGYEVLDAAGSFDNSSLCSGGGDKAVVLWDVASGQVVRK 104 Query: 343 FRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARK 230 FRGH V + ++ ++ ++LSGS DS+++ WD R+R+ Sbjct: 105 FRGHAGKVNTVQFNEEATVILSGSIDSSIRCWDCRSRR 142 Score = 37.7 bits (86), Expect = 0.020 Identities = 24/89 (26%), Positives = 44/89 (49%), Gaps = 2/89 (2%) Frame = -2 Query: 433 FSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR--LLLSGSKDST 260 FS DGQ +S D +++L + TG+ + ++GH Y++ R ++S S+D Sbjct: 199 FSRDGQCTLVSSLDSTLRLLDKDTGELLGEYKGHKNQEYKLDCCLSERDTHVVSCSEDGK 258 Query: 259 LKVWDIRARKLKQDLPGHADEVYAVDWSP 173 + WD+ L LP + V ++ + P Sbjct: 259 VFFWDLVEGALALALPVGSGVVQSLAYHP 287
>GBB_MAIZE (P49178) Guanine nucleotide-binding protein beta subunit| Length = 380 Score = 71.2 bits (173), Expect = 2e-12 Identities = 42/124 (33%), Positives = 74/124 (59%), Gaps = 8/124 (6%) Frame = -2 Query: 469 MTGHQKVVNHVYFSPDGQW-LASASFDKSVKLWNGITGKFVTAF-----RGHVADVYQIS 308 +TGH+ V+ + PD + L ++S D++ LW+ TG+ ++ F GH ADV +S Sbjct: 153 LTGHKGYVSSCQYVPDQETRLITSSGDQTCVLWDVTTGQRISIFGGEFPSGHTADVQSVS 212 Query: 307 W-SADSRLLLSGSKDSTLKVWDIR-ARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRA 134 S+++ + +SGS D+T+++WDIR A + + GH D+V +V + PDG + +G D Sbjct: 213 INSSNTNMFVSGSCDTTVRLWDIRIASRAVRTYHGHEDDVNSVKFFPDGHRFGTGSDDGT 272 Query: 133 LKLW 122 +L+ Sbjct: 273 CRLF 276 Score = 62.0 bits (149), Expect = 1e-09 Identities = 42/149 (28%), Positives = 68/149 (45%), Gaps = 11/149 (7%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SGS D T+ LW+ I+ + GH+ VN V F PDG + S D + +L++ TG Sbjct: 223 SGSCDTTVRLWDIRIASRAVRTYHGHEDDVNSVKFFPDGHRFGTGSDDGTCRLFDMRTGH 282 Query: 355 FVTAF-------RGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDL----PG 209 + + + V I++S RLL +G + VWD ++ +L Sbjct: 283 QLQVYSREPDRNSNELPTVTSIAFSISGRLLFAGYSNGDCYVWDTLLAEVVLNLGNLQNS 342 Query: 208 HADEVYAVDWSPDGEKVVSGGKDRALKLW 122 H + + S DG + +G D+ LK+W Sbjct: 343 HDGRISCLGMSSDGSALCTGSWDKNLKIW 371 Score = 48.5 bits (114), Expect = 1e-05 Identities = 28/124 (22%), Positives = 60/124 (48%), Gaps = 8/124 (6%) Frame = -2 Query: 469 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 290 + GH V + ++P+ W+ SAS D + +WN +T + A + H V +++ + + Sbjct: 62 LQGHSGKVYSLDWTPEKNWIVSASQDGRLIVWNALTSQKTHAIKLHCPWVMACAFAPNGQ 121 Query: 289 LLLSGSKDSTLKVWDIRAR-------KLKQDLPGHADEVYAVDWSPDGE-KVVSGGKDRA 134 + G DS ++++ ++ + + L GH V + + PD E ++++ D+ Sbjct: 122 SVACGGLDSACSIFNLNSQADRDGNMPVSRILTGHKGYVSSCQYVPDQETRLITSSGDQT 181 Query: 133 LKLW 122 LW Sbjct: 182 CVLW 185
>RBBP7_BRARE (Q7ZTY4) Histone-binding protein RBBP7 (Retinoblastoma-binding| protein 7) (RBBP-7) Length = 426 Score = 71.2 bits (173), Expect = 2e-12 Identities = 53/153 (34%), Positives = 77/153 (50%), Gaps = 15/153 (9%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKAR--------MTGHQKVVNHVYFSPDGQWL-ASASFDKSV 383 S SDD T+ LW+ IS PK TGH VV V + + L S + D+ + Sbjct: 195 SASDDHTICLWD--ISGAPKEGKIVDAKTIFTGHTAVVEDVSWHLLHESLFGSVADDQKL 252 Query: 382 KLWN---GITGKFVTAFRGHVADVYQISWSADSRLLLS-GSKDSTLKVWDIRARKLK-QD 218 +W+ T K + H A+V +S++ S +L+ GS D T+ +WD+R KLK Sbjct: 253 MIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHS 312 Query: 217 LPGHADEVYAVDWSPDGEKVV-SGGKDRALKLW 122 H DE++ V WSP E ++ S G DR L +W Sbjct: 313 FESHKDEIFQVQWSPHNETILASSGTDRRLNVW 345 Score = 35.0 bits (79), Expect = 0.13 Identities = 27/82 (32%), Positives = 37/82 (45%), Gaps = 9/82 (10%) Frame = -2 Query: 340 RGHVADVYQISWSAD-SRLLLSGSKDSTLKVWDI-------RARKLKQDLPGHADEVYAV 185 RGH + Y +SW+ + S LLS S D T+ +WDI + K GH V V Sbjct: 174 RGHQKEGYGLSWNPNLSGNLLSASDDHTICLWDISGAPKEGKIVDAKTIFTGHTAVVEDV 233 Query: 184 DWSPDGEKVV-SGGKDRALKLW 122 W E + S D+ L +W Sbjct: 234 SWHLLHESLFGSVADDQKLMIW 255
>RBP4B_XENLA (Q6INH0) Histone-binding protein RBBP4-B (Retinoblastoma-binding| protein 4-B) (RBBP-4-B) (Retinoblastoma-binding protein p48-B) Length = 424 Score = 71.2 bits (173), Expect = 2e-12 Identities = 53/153 (34%), Positives = 77/153 (50%), Gaps = 15/153 (9%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKAR--------MTGHQKVVNHVYFSPDGQWL-ASASFDKSV 383 S SDD T+ LW+ IS PK TGH VV V + + L S + D+ + Sbjct: 194 SASDDHTICLWD--ISAVPKEGKVVDAKTIFTGHTAVVEDVSWHLLHESLFGSVADDQKL 251 Query: 382 KLWN---GITGKFVTAFRGHVADVYQISWSADSRLLLS-GSKDSTLKVWDIRARKLK-QD 218 +W+ T K + H A+V +S++ S +L+ GS D T+ +WD+R KLK Sbjct: 252 MIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHS 311 Query: 217 LPGHADEVYAVDWSPDGEKVV-SGGKDRALKLW 122 H DE++ V WSP E ++ S G DR L +W Sbjct: 312 FESHKDEIFQVQWSPHNETILASSGTDRRLNVW 344 Score = 35.8 bits (81), Expect = 0.078 Identities = 28/82 (34%), Positives = 37/82 (45%), Gaps = 9/82 (10%) Frame = -2 Query: 340 RGHVADVYQISWSAD-SRLLLSGSKDSTLKVWDIRA-------RKLKQDLPGHADEVYAV 185 RGH + Y +SW+ + S LLS S D T+ +WDI A K GH V V Sbjct: 173 RGHQKEGYGLSWNPNLSGNLLSASDDHTICLWDISAVPKEGKVVDAKTIFTGHTAVVEDV 232 Query: 184 DWSPDGEKVV-SGGKDRALKLW 122 W E + S D+ L +W Sbjct: 233 SWHLLHESLFGSVADDQKLMIW 254
>RBP4A_XENLA (O93377) Histone-binding protein RBBP4-A (Retinoblastoma-binding| protein 4-A) (RBBP-4-A) (Retinoblastoma-binding protein p48-A) Length = 424 Score = 71.2 bits (173), Expect = 2e-12 Identities = 53/153 (34%), Positives = 77/153 (50%), Gaps = 15/153 (9%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKAR--------MTGHQKVVNHVYFSPDGQWL-ASASFDKSV 383 S SDD T+ LW+ IS PK TGH VV V + + L S + D+ + Sbjct: 194 SASDDHTICLWD--ISAVPKEGKVVDAKTIFTGHTAVVEDVSWHLLHESLFGSVADDQKL 251 Query: 382 KLWN---GITGKFVTAFRGHVADVYQISWSADSRLLLS-GSKDSTLKVWDIRARKLK-QD 218 +W+ T K + H A+V +S++ S +L+ GS D T+ +WD+R KLK Sbjct: 252 MIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHS 311 Query: 217 LPGHADEVYAVDWSPDGEKVV-SGGKDRALKLW 122 H DE++ V WSP E ++ S G DR L +W Sbjct: 312 FESHKDEIFQVQWSPHNETILASSGTDRRLNVW 344 Score = 35.8 bits (81), Expect = 0.078 Identities = 28/82 (34%), Positives = 37/82 (45%), Gaps = 9/82 (10%) Frame = -2 Query: 340 RGHVADVYQISWSAD-SRLLLSGSKDSTLKVWDIRA-------RKLKQDLPGHADEVYAV 185 RGH + Y +SW+ + S LLS S D T+ +WDI A K GH V V Sbjct: 173 RGHQKEGYGLSWNPNLSGNLLSASDDHTICLWDISAVPKEGKVVDAKTIFTGHTAVVEDV 232 Query: 184 DWSPDGEKVV-SGGKDRALKLW 122 W E + S D+ L +W Sbjct: 233 SWHLLHESLFGSVADDQKLMIW 254
>RBBP4_XENTR (Q5M7K4) Histone-binding protein RBBP4 (Retinoblastoma-binding| protein 4) (RBBP-4) Length = 424 Score = 71.2 bits (173), Expect = 2e-12 Identities = 53/153 (34%), Positives = 77/153 (50%), Gaps = 15/153 (9%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKAR--------MTGHQKVVNHVYFSPDGQWL-ASASFDKSV 383 S SDD T+ LW+ IS PK TGH VV V + + L S + D+ + Sbjct: 194 SASDDHTICLWD--ISAVPKEGKVVDAKTIFTGHTAVVEDVSWHLLHESLFGSVADDQKL 251 Query: 382 KLWN---GITGKFVTAFRGHVADVYQISWSADSRLLLS-GSKDSTLKVWDIRARKLK-QD 218 +W+ T K + H A+V +S++ S +L+ GS D T+ +WD+R KLK Sbjct: 252 MIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHS 311 Query: 217 LPGHADEVYAVDWSPDGEKVV-SGGKDRALKLW 122 H DE++ V WSP E ++ S G DR L +W Sbjct: 312 FESHKDEIFQVQWSPHNETILASSGTDRRLNVW 344 Score = 35.8 bits (81), Expect = 0.078 Identities = 28/82 (34%), Positives = 37/82 (45%), Gaps = 9/82 (10%) Frame = -2 Query: 340 RGHVADVYQISWSAD-SRLLLSGSKDSTLKVWDIRA-------RKLKQDLPGHADEVYAV 185 RGH + Y +SW+ + S LLS S D T+ +WDI A K GH V V Sbjct: 173 RGHQKEGYGLSWNPNLSGNLLSASDDHTICLWDISAVPKEGKVVDAKTIFTGHTAVVEDV 232 Query: 184 DWSPDGEKVV-SGGKDRALKLW 122 W E + S D+ L +W Sbjct: 233 SWHLLHESLFGSVADDQKLMIW 254
>RBBP4_PONPY (Q5RF92) Histone-binding protein RBBP4 (Retinoblastoma-binding| protein 4) (RBBP-4) Length = 424 Score = 71.2 bits (173), Expect = 2e-12 Identities = 53/153 (34%), Positives = 77/153 (50%), Gaps = 15/153 (9%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKAR--------MTGHQKVVNHVYFSPDGQWL-ASASFDKSV 383 S SDD T+ LW+ IS PK TGH VV V + + L S + D+ + Sbjct: 194 SASDDHTICLWD--ISAVPKEGKVVDAKTIFTGHTAVVEDVSWHLLHESLFGSVADDQKL 251 Query: 382 KLWN---GITGKFVTAFRGHVADVYQISWSADSRLLLS-GSKDSTLKVWDIRARKLK-QD 218 +W+ T K + H A+V +S++ S +L+ GS D T+ +WD+R KLK Sbjct: 252 MIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHS 311 Query: 217 LPGHADEVYAVDWSPDGEKVV-SGGKDRALKLW 122 H DE++ V WSP E ++ S G DR L +W Sbjct: 312 FESHKDEIFQVQWSPHNETILASSGTDRRLNVW 344 Score = 35.8 bits (81), Expect = 0.078 Identities = 28/82 (34%), Positives = 37/82 (45%), Gaps = 9/82 (10%) Frame = -2 Query: 340 RGHVADVYQISWSAD-SRLLLSGSKDSTLKVWDIRA-------RKLKQDLPGHADEVYAV 185 RGH + Y +SW+ + S LLS S D T+ +WDI A K GH V V Sbjct: 173 RGHQKEGYGLSWNPNLSGHLLSASDDHTICLWDISAVPKEGKVVDAKTIFTGHTAVVEDV 232 Query: 184 DWSPDGEKVV-SGGKDRALKLW 122 W E + S D+ L +W Sbjct: 233 SWHLLHESLFGSVADDQKLMIW 254
>RBBP4_MOUSE (Q60972) Histone-binding protein RBBP4 (Retinoblastoma-binding| protein 4) (RBBP-4) (Retinoblastoma-binding protein p48) (Chromatin assembly factor 1 subunit C) (CAF-1 subunit C) (Chromatin assembly factor I p48 subunit) (CAF-I 48 kDa subunit) Length = 424 Score = 71.2 bits (173), Expect = 2e-12 Identities = 53/153 (34%), Positives = 77/153 (50%), Gaps = 15/153 (9%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKAR--------MTGHQKVVNHVYFSPDGQWL-ASASFDKSV 383 S SDD T+ LW+ IS PK TGH VV V + + L S + D+ + Sbjct: 194 SASDDHTICLWD--ISAVPKKGKVVDAKTIFTGHTAVVEDVSWHLLHESLFGSVADDQKL 251 Query: 382 KLWN---GITGKFVTAFRGHVADVYQISWSADSRLLLS-GSKDSTLKVWDIRARKLK-QD 218 +W+ T K + H A+V +S++ S +L+ GS D T+ +WD+R KLK Sbjct: 252 MIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHS 311 Query: 217 LPGHADEVYAVDWSPDGEKVV-SGGKDRALKLW 122 H DE++ V WSP E ++ S G DR L +W Sbjct: 312 FESHKDEIFQVQWSPHNETILASSGTDRRLNVW 344 Score = 36.2 bits (82), Expect = 0.059 Identities = 28/82 (34%), Positives = 38/82 (46%), Gaps = 9/82 (10%) Frame = -2 Query: 340 RGHVADVYQISWSAD-SRLLLSGSKDSTLKVWDIRARKLKQDL-------PGHADEVYAV 185 RGH + Y +SW+ + S LLS S D T+ +WDI A K + GH V V Sbjct: 173 RGHQKEGYGLSWNPNLSGHLLSASDDHTICLWDISAVPKKGKVVDAKTIFTGHTAVVEDV 232 Query: 184 DWSPDGEKVV-SGGKDRALKLW 122 W E + S D+ L +W Sbjct: 233 SWHLLHESLFGSVADDQKLMIW 254
>RBBP4_HUMAN (Q09028) Histone-binding protein RBBP4 (Retinoblastoma-binding| protein 4) (RBBP-4) (Retinoblastoma-binding protein p48) (Chromatin assembly factor 1 subunit C) (CAF-1 subunit C) (Chromatin assembly factor I p48 subunit) (CAF-I 48 kDa subunit) Length = 424 Score = 71.2 bits (173), Expect = 2e-12 Identities = 53/153 (34%), Positives = 77/153 (50%), Gaps = 15/153 (9%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKAR--------MTGHQKVVNHVYFSPDGQWL-ASASFDKSV 383 S SDD T+ LW+ IS PK TGH VV V + + L S + D+ + Sbjct: 194 SASDDHTICLWD--ISAVPKEGKVVDAKTIFTGHTAVVEDVSWHLLHESLFGSVADDQKL 251 Query: 382 KLWN---GITGKFVTAFRGHVADVYQISWSADSRLLLS-GSKDSTLKVWDIRARKLK-QD 218 +W+ T K + H A+V +S++ S +L+ GS D T+ +WD+R KLK Sbjct: 252 MIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHS 311 Query: 217 LPGHADEVYAVDWSPDGEKVV-SGGKDRALKLW 122 H DE++ V WSP E ++ S G DR L +W Sbjct: 312 FESHKDEIFQVQWSPHNETILASSGTDRRLNVW 344 Score = 35.8 bits (81), Expect = 0.078 Identities = 28/82 (34%), Positives = 37/82 (45%), Gaps = 9/82 (10%) Frame = -2 Query: 340 RGHVADVYQISWSAD-SRLLLSGSKDSTLKVWDIRA-------RKLKQDLPGHADEVYAV 185 RGH + Y +SW+ + S LLS S D T+ +WDI A K GH V V Sbjct: 173 RGHQKEGYGLSWNPNLSGHLLSASDDHTICLWDISAVPKEGKVVDAKTIFTGHTAVVEDV 232 Query: 184 DWSPDGEKVV-SGGKDRALKLW 122 W E + S D+ L +W Sbjct: 233 SWHLLHESLFGSVADDQKLMIW 254
>RBBP4_CHICK (Q9W7I5) Histone-binding protein RBBP4 (Retinoblastoma-binding| protein 4) (RBBP-4) (Retinoblastoma-binding protein p48) (Chromatin assembly factor 1 subunit C) (CAF-1 subunit C) (Chromatin assembly factor I p48 subunit) (CAF-I 48 kDa subunit) Length = 424 Score = 71.2 bits (173), Expect = 2e-12 Identities = 53/153 (34%), Positives = 77/153 (50%), Gaps = 15/153 (9%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKAR--------MTGHQKVVNHVYFSPDGQWL-ASASFDKSV 383 S SDD T+ LW+ IS PK TGH VV V + + L S + D+ + Sbjct: 194 SASDDHTICLWD--ISAVPKEGKVVDAKTIFTGHTAVVEDVSWHLLHESLFGSVADDQKL 251 Query: 382 KLWN---GITGKFVTAFRGHVADVYQISWSADSRLLLS-GSKDSTLKVWDIRARKLK-QD 218 +W+ T K + H A+V +S++ S +L+ GS D T+ +WD+R KLK Sbjct: 252 MIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHS 311 Query: 217 LPGHADEVYAVDWSPDGEKVV-SGGKDRALKLW 122 H DE++ V WSP E ++ S G DR L +W Sbjct: 312 FESHKDEIFQVQWSPHNETILASSGTDRRLNVW 344 Score = 35.8 bits (81), Expect = 0.078 Identities = 28/82 (34%), Positives = 37/82 (45%), Gaps = 9/82 (10%) Frame = -2 Query: 340 RGHVADVYQISWSAD-SRLLLSGSKDSTLKVWDIRA-------RKLKQDLPGHADEVYAV 185 RGH + Y +SW+ + S LLS S D T+ +WDI A K GH V V Sbjct: 173 RGHQKEGYGLSWNPNLSGHLLSASDDHTICLWDISAVPKEGKVVDAKTIFTGHTAVVEDV 232 Query: 184 DWSPDGEKVV-SGGKDRALKLW 122 W E + S D+ L +W Sbjct: 233 SWHLLHESLFGSVADDQKLMIW 254
>RBBP4_BOVIN (Q3MHL3) Histone-binding protein RBBP4 (Retinoblastoma-binding| protein 4) (RBBP-4) Length = 424 Score = 71.2 bits (173), Expect = 2e-12 Identities = 53/153 (34%), Positives = 77/153 (50%), Gaps = 15/153 (9%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKAR--------MTGHQKVVNHVYFSPDGQWL-ASASFDKSV 383 S SDD T+ LW+ IS PK TGH VV V + + L S + D+ + Sbjct: 194 SASDDHTICLWD--ISAVPKEGKVVDAKTIFTGHTAVVEDVSWHLLHESLFGSVADDQKL 251 Query: 382 KLWN---GITGKFVTAFRGHVADVYQISWSADSRLLLS-GSKDSTLKVWDIRARKLK-QD 218 +W+ T K + H A+V +S++ S +L+ GS D T+ +WD+R KLK Sbjct: 252 MIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHS 311 Query: 217 LPGHADEVYAVDWSPDGEKVV-SGGKDRALKLW 122 H DE++ V WSP E ++ S G DR L +W Sbjct: 312 FESHKDEIFQVQWSPHNETILASSGTDRRLNVW 344 Score = 35.8 bits (81), Expect = 0.078 Identities = 28/82 (34%), Positives = 37/82 (45%), Gaps = 9/82 (10%) Frame = -2 Query: 340 RGHVADVYQISWSAD-SRLLLSGSKDSTLKVWDIRA-------RKLKQDLPGHADEVYAV 185 RGH + Y +SW+ + S LLS S D T+ +WDI A K GH V V Sbjct: 173 RGHQKEGYGLSWNPNLSGHLLSASDDHTICLWDISAVPKEGKVVDAKTIFTGHTAVVEDV 232 Query: 184 DWSPDGEKVV-SGGKDRALKLW 122 W E + S D+ L +W Sbjct: 233 SWHLLHESLFGSVADDQKLMIW 254
>HIRA_DROME (O17468) HIRA protein homolog (dHIRA)| Length = 1047 Score = 71.2 bits (173), Expect = 2e-12 Identities = 55/166 (33%), Positives = 76/166 (45%), Gaps = 29/166 (17%) Frame = -2 Query: 532 GSDDFTMFLWE--PTISKQ-------PK--ARMTGHQKVVNHVYFSPDGQWLASASFDKS 386 GSD + +W P +S + PK +M H VN V +S +GQ LAS S DK Sbjct: 34 GSDCGRVVIWNLLPVLSDKAEFDADVPKMLCQMDQHLACVNCVRWSQNGQNLASGSDDKL 93 Query: 385 VKLWN---GITGKFVTA--------------FRGHVADVYQISWSADSRLLLSGSKDSTL 257 + +W G +G F T RGH DV ++WS + L S S D+T+ Sbjct: 94 IMIWRKSAGSSGVFGTGGMQKNHESWKCFYTLRGHDGDVLDLAWSPNDVYLASCSIDNTV 153 Query: 256 KVWDIRA-RKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 +WD +A L GH V V W P G + S DR++K+W Sbjct: 154 IIWDAQAFPHSVATLKGHTGLVKGVSWDPLGRFLASQSDDRSIKIW 199 Score = 57.0 bits (136), Expect = 3e-08 Identities = 45/165 (27%), Positives = 71/165 (43%), Gaps = 26/165 (15%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWN----G 368 S S D T+ +W+ A + GH +V V + P G++LAS S D+S+K+WN Sbjct: 146 SCSIDNTVIIWDAQAFPHSVATLKGHTGLVKGVSWDPLGRFLASQSDDRSIKIWNTMNWS 205 Query: 367 ITGKFVTAFR--GHVADVYQISWSADSRLLLS----GSKDSTLKVWDIRARKLKQDLPGH 206 ++ F G + ++SWS D + L+S T ++ + K +D GH Sbjct: 206 LSHTITEPFEECGGTTHILRLSWSPDGQYLVSAHAMNGGGPTAQIIEREGWKCDKDFVGH 265 Query: 205 ADEVYAV------------DWSPDGEK----VVSGGKDRALKLWM 119 V V D SP + G +DR+L +WM Sbjct: 266 RKAVTCVRFHNSILSRQENDGSPSKPLQYCCLAVGSRDRSLSVWM 310
>MORG1_BRARE (Q6DH44) Mitogen-activated protein kinase organizer 1 (MAPK| organizer 1) Length = 315 Score = 71.2 bits (173), Expect = 2e-12 Identities = 36/112 (32%), Positives = 60/112 (53%) Frame = -2 Query: 457 QKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLS 278 Q V V F+ DG +L + DKS+KLW+ G + + GH +V S D+ L S Sbjct: 25 QGAVRAVRFNADGNYLLTCGSDKSLKLWSVSRGTLLKTYSGHGYEVLDADGSYDNSQLCS 84 Query: 277 GSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 S D T+ +WD+ + ++ + L GHA +V V ++ + ++SG D ++ W Sbjct: 85 CSSDKTVILWDVASGQVTRKLRGHAGKVNCVQFNEEATVMLSGSIDGTVRCW 136 Score = 56.6 bits (135), Expect = 4e-08 Identities = 32/100 (32%), Positives = 52/100 (52%) Frame = -2 Query: 466 TGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRL 287 +GH V S D L S S DK+V LW+ +G+ RGH V + ++ ++ + Sbjct: 64 SGHGYEVLDADGSYDNSQLCSCSSDKTVILWDVASGQVTRKLRGHAGKVNCVQFNEEATV 123 Query: 286 LLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDG 167 +LSGS D T++ WD R+R++ + + +D S DG Sbjct: 124 MLSGSIDGTVRCWDTRSRRM--------EPIQILDESQDG 155 Score = 47.4 bits (111), Expect = 3e-05 Identities = 39/140 (27%), Positives = 65/140 (46%), Gaps = 3/140 (2%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 S S D T+ LW+ S Q ++ GH VN V F+ + + S S D +V+ W+ + + Sbjct: 84 SCSSDKTVILWD-VASGQVTRKLRGHAGKVNCVQFNEEATVMLSGSIDGTVRCWDTRSRR 142 Query: 355 FVTAFRGHVADVYQ---ISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAV 185 + D Q S LL+GS D ++ +D+R +L+ D G + V Sbjct: 143 MEPI---QILDESQDGISSLKVSEHELLTGSVDGRVRRYDLRMGQLQVDYIG--SPITCV 197 Query: 184 DWSPDGEKVVSGGKDRALKL 125 +S DG+ +S D ++L Sbjct: 198 CFSRDGQCTLSSSLDSTVRL 217 Score = 44.3 bits (103), Expect = 2e-04 Identities = 30/108 (27%), Positives = 55/108 (50%), Gaps = 2/108 (1%) Frame = -2 Query: 439 VYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR--LLLSGSKD 266 V FS DGQ S+S D +V+L + TG+ + + GHV Y++ + +LS S+D Sbjct: 197 VCFSRDGQCTLSSSLDSTVRLLDKSTGEMLGEYSGHVNKGYKLDCCLTDKDTHVLSCSED 256 Query: 265 STLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 + WD+ L LP V ++ + P ++++ + R +++W Sbjct: 257 GHVYYWDLVEGSLTLKLPVGKAVVQSLSFHPTEPRLLTSMEGR-VQVW 303
>WDR1_MOUSE (O88342) WD-repeat protein 1 (Actin-interacting protein 1) (AIP1)| Length = 605 Score = 70.9 bits (172), Expect = 2e-12 Identities = 43/111 (38%), Positives = 58/111 (52%), Gaps = 3/111 (2%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 +GSDD +E K K + H + VN V FSPDG A+AS D + +++G TG+ Sbjct: 163 TGSDDNCAAFFEGPPFKF-KFTIGDHSRFVNCVRFSPDGNRFATASADGQIFIYDGKTGE 221 Query: 355 FVTAF---RGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLP 212 V A + H +Y ISWS DS LLS S D T K+WD+ + P Sbjct: 222 KVCALGESKAHDGGIYAISWSPDSTHLLSASGDKTSKIWDVNVNSVVSTFP 272 Score = 53.9 bits (128), Expect = 3e-07 Identities = 37/135 (27%), Positives = 58/135 (42%), Gaps = 4/135 (2%) Frame = -2 Query: 514 MFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQW-LASASFDKSVKLWNGITGKFVTAFR 338 +FLW+ S +TGH KV+N V + LA+ S D + G KF Sbjct: 129 VFLWDTGSSV---GEITGHNKVINSVDIKQTRPYRLATGSDDNCAAFFEGPPFKFKFTIG 185 Query: 337 GHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDL---PGHADEVYAVDWSPDG 167 H V + +S D + S D + ++D + + L H +YA+ WSPD Sbjct: 186 DHSRFVNCVRFSPDGNRFATASADGQIFIYDGKTGEKVCALGESKAHDGGIYAISWSPDS 245 Query: 166 EKVVSGGKDRALKLW 122 ++S D+ K+W Sbjct: 246 THLLSASGDKTSKIW 260 Score = 39.7 bits (91), Expect = 0.005 Identities = 31/112 (27%), Positives = 49/112 (43%), Gaps = 3/112 (2%) Frame = -2 Query: 448 VNHVYFSPDGQWLASASFDKSVKLWNGITGKFVT-AFRGHVADVYQISWSADSRLLLSGS 272 V V +S DG +LA K V +++ G F GH A + ++WS D+ SG Sbjct: 491 VTDVAYSHDGAFLAVCDASKVVTVFSVADGYSENNVFYGHHAKIVCLAWSPDNEHFASGG 550 Query: 271 KDSTLKVWDIR--ARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 D + VW + K+K V ++ W D +V+ D ++K W Sbjct: 551 MDMMVYVWTLSDPETKVKIQDAHRLHHVSSLAWL-DEHTLVTTSHDASVKEW 601 Score = 36.6 bits (83), Expect = 0.045 Identities = 28/109 (25%), Positives = 50/109 (45%), Gaps = 7/109 (6%) Frame = -2 Query: 427 PDGQWLASASFDKSVKLWNGIT------GKFVTAFRGHVADVYQISWSADSRLLLSGSKD 266 P G +A D +V++++ + GK + A +G V DV ++S D L Sbjct: 454 PGGDTVAVGGTDGNVRVYSILASTLKDEGKLLEA-KGPVTDV---AYSHDGAFLAVCDAS 509 Query: 265 STLKVWDIRARKLKQDL-PGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 + V+ + + ++ GH ++ + WSPD E SGG D + +W Sbjct: 510 KVVTVFSVADGYSENNVFYGHHAKIVCLAWSPDNEHFASGGMDMMVYVW 558 Score = 31.6 bits (70), Expect = 1.5 Identities = 23/78 (29%), Positives = 35/78 (44%), Gaps = 4/78 (5%) Frame = -2 Query: 463 GHQKVVNHVYFSPDGQWLASASFDKSVKLWN----GITGKFVTAFRGHVADVYQISWSAD 296 GH + + +SPD + AS D V +W K A R H V ++W D Sbjct: 529 GHHAKIVCLAWSPDNEHFASGGMDMMVYVWTLSDPETKVKIQDAHRLH--HVSSLAW-LD 585 Query: 295 SRLLLSGSKDSTLKVWDI 242 L++ S D+++K W I Sbjct: 586 EHTLVTTSHDASVKEWTI 603
>POF1_SCHPO (P87053) F-box/WD-repeat protein pof1 (Skp1-binding protein 1)| Length = 605 Score = 70.9 bits (172), Expect = 2e-12 Identities = 48/144 (33%), Positives = 72/144 (50%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SGS D T+ LW S + + GH VN V D + S S D ++K+W+ T Sbjct: 368 SGSADCTVKLWH--FSGGKRITLRGHTGPVNSVRIIRDRGLVLSGSDDSTIKIWSLETNT 425 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 + F H+ V ++ ADSRL S S D T+K WDI +K L GH + V+ + + Sbjct: 426 CLHTFSAHIGPVQSLAL-ADSRLF-SCSLDGTIKQWDIEKKKCVHTLFGHIEGVWEI--A 481 Query: 175 PDGEKVVSGGKDRALKLWMN*ACL 104 D +++SG D +K+W C+ Sbjct: 482 ADHLRLISGAHDGVVKVWEACECV 505 Score = 62.8 bits (151), Expect = 6e-10 Identities = 35/97 (36%), Positives = 53/97 (54%) Frame = -2 Query: 412 LASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRAR 233 LAS S+D +++LWN T + V GH + V + + D L+SGS D T+++W+ R Sbjct: 286 LASGSYDATIRLWNLATFQQVALLEGHSSGVTCLQF--DQCKLISGSMDKTIRIWNYRTS 343 Query: 232 KLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 + L GH D V + + D +VSG D +KLW Sbjct: 344 ECISILHGHTDSVLCLTF--DSTLLVSGSADCTVKLW 378 Score = 57.4 bits (137), Expect = 2e-08 Identities = 44/138 (31%), Positives = 63/138 (45%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SGS D T+ +W S+ + GH V + F D L S S D +VKLW+ GK Sbjct: 328 SGSMDKTIRIWNYRTSECISI-LHGHTDSVLCLTF--DSTLLVSGSADCTVKLWHFSGGK 384 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 +T RGH V + D L+LSGS DST+K+W + H V ++ + Sbjct: 385 RIT-LRGHTGPVNSVRIIRDRGLVLSGSDDSTIKIWSLETNTCLHTFSAHIGPVQSLALA 443 Query: 175 PDGEKVVSGGKDRALKLW 122 ++ S D +K W Sbjct: 444 --DSRLFSCSLDGTIKQW 459 Score = 37.7 bits (86), Expect = 0.020 Identities = 17/56 (30%), Positives = 34/56 (60%) Frame = -2 Query: 289 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 +L SGS D+T+++W++ + L GH+ V + + D K++SG D+ +++W Sbjct: 285 ILASGSYDATIRLWNLATFQQVALLEGHSSGVTCLQF--DQCKLISGSMDKTIRIW 338
>CAF1B_HUMAN (Q13112) Chromatin assembly factor 1 subunit B (CAF-1 subunit B)| (Chromatin assembly factor I p60 subunit) (CAF-I 60 kDa subunit) (CAF-Ip60) (M-phase phosphoprotein 7) Length = 559 Score = 70.9 bits (172), Expect = 2e-12 Identities = 43/139 (30%), Positives = 59/139 (42%), Gaps = 21/139 (15%) Frame = -2 Query: 475 ARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK-------------------- 356 + + H K VN V FSP G+ LAS D + LW K Sbjct: 60 SNLARHTKAVNVVRFSPTGEILASGGDDAVILLWKVNDNKEPEQIAFQDEDEAQLNKENW 119 Query: 355 -FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDW 179 V RGH+ DVY I W+ D L+ S S D+T +WD+ + H V V W Sbjct: 120 TVVKTLRGHLEDVYDICWATDGNLMASASVDNTAIIWDVSKGQKISIFNEHKSYVQGVTW 179 Query: 178 SPDGEKVVSGGKDRALKLW 122 P G+ V + DR L+++ Sbjct: 180 DPLGQYVATLSCDRVLRVY 198 Score = 50.1 bits (118), Expect = 4e-06 Identities = 29/123 (23%), Positives = 58/123 (47%), Gaps = 20/123 (16%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKA--------------------RMTGHQKVVNHVYFSPDGQ 416 SG DD + LW+ +K+P+ + GH + V + ++ DG Sbjct: 83 SGGDDAVILLWKVNDNKEPEQIAFQDEDEAQLNKENWTVVKTLRGHLEDVYDICWATDGN 142 Query: 415 WLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRA 236 +ASAS D + +W+ G+ ++ F H + V ++W + + + S D L+V+ I+ Sbjct: 143 LMASASVDNTAIIWDVSKGQKISIFNEHKSYVQGVTWDPLGQYVATLSCDRVLRVYSIQK 202 Query: 235 RKL 227 +++ Sbjct: 203 KRV 205
>FBXW7_DROME (Q9VZF4) F-box/WD-repeat protein 7 (F-box and WD-40 domain protein 7)| (Protein archipelago) Length = 1326 Score = 70.9 bits (172), Expect = 2e-12 Identities = 41/128 (32%), Positives = 63/128 (49%) Frame = -2 Query: 505 WEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVA 326 W ++PK V+ + FS G + S S D ++K+W+ + GK + GH Sbjct: 979 WRSRPVRKPKVLKGHDDHVITCLQFS--GNRIVSGSDDNTLKVWSAVNGKCLRTLVGHTG 1036 Query: 325 DVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGG 146 V+ S + +++SGS D TLKVWD+ + L GH V + G KVVSG Sbjct: 1037 GVWSSQMSGN--IIISGSTDRTLKVWDMDSGACVHTLQGHTSTVRCMHL--HGSKVVSGS 1092 Query: 145 KDRALKLW 122 +D L++W Sbjct: 1093 RDATLRVW 1100 Score = 63.2 bits (152), Expect = 5e-10 Identities = 40/138 (28%), Positives = 72/138 (52%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SGS D T+ +W+ S + GH V ++ G + S S D ++++W+ G Sbjct: 1050 SGSTDRTLKVWDMD-SGACVHTLQGHTSTVRCMHLH--GSKVVSGSRDATLRVWDIEQGS 1106 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 + GH+A V + + D +L++SG+ D +K+W ++ L GH + VY++ + Sbjct: 1107 CLHVLVGHLAAVRCVQY--DGKLIVSGAYDYMVKIWHPERQECLHTLQGHTNRVYSLQF- 1163 Query: 175 PDGEKVVSGGKDRALKLW 122 DG VVSG D ++++W Sbjct: 1164 -DGLHVVSGSLDTSIRVW 1180 Score = 57.8 bits (138), Expect = 2e-08 Identities = 42/141 (29%), Positives = 66/141 (46%), Gaps = 3/141 (2%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SG+ D+ + +W P ++ + GH V + F DG + S S D S+++W+ TG Sbjct: 1130 SGAYDYMVKIWHPE-RQECLHTLQGHTNRVYSLQF--DGLHVVSGSLDTSIRVWDVETGN 1186 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPG---HADEVYAV 185 GH + +L+SG+ DST+KVWDI + Q L G H V + Sbjct: 1187 CKHTLMGHQS--LTSGMELRQNILVSGNADSTVKVWDITTGQCLQTLSGPNKHHSAVTCL 1244 Query: 184 DWSPDGEKVVSGGKDRALKLW 122 + + VV+ D +KLW Sbjct: 1245 QF--NSRFVVTSSDDGTVKLW 1263
>MORG1_XENTR (Q5XGI5) Mitogen-activated protein kinase organizer 1 (MAPK| organizer 1) Length = 314 Score = 70.9 bits (172), Expect = 2e-12 Identities = 34/126 (26%), Positives = 67/126 (53%) Frame = -2 Query: 499 PTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADV 320 P + ++ + ++ +Q V V F+ DG + + DK++KLWN G + + GH +V Sbjct: 11 PELPQKLQHKLECNQGAVRAVRFNVDGNYCMTCGSDKTLKLWNPHKGTLLKTYSGHGYEV 70 Query: 319 YQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKD 140 + S D+ + S S D T+ +WD+ ++ + GHA +V V ++ + ++SG D Sbjct: 71 LDTAGSYDNSQMCSCSSDKTVILWDVAQGQVVRKFRGHAGKVNCVQFNEEATVIMSGSID 130 Query: 139 RALKLW 122 +++ W Sbjct: 131 SSIRCW 136 Score = 61.2 bits (147), Expect = 2e-09 Identities = 34/98 (34%), Positives = 53/98 (54%) Frame = -2 Query: 523 DFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTA 344 D T+ LW P K +GH V S D + S S DK+V LW+ G+ V Sbjct: 46 DKTLKLWNPHKGTLLKT-YSGHGYEVLDTAGSYDNSQMCSCSSDKTVILWDVAQGQVVRK 104 Query: 343 FRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARK 230 FRGH V + ++ ++ +++SGS DS+++ WD R+R+ Sbjct: 105 FRGHAGKVNCVQFNEEATVIMSGSIDSSIRCWDCRSRR 142 Score = 42.7 bits (99), Expect = 6e-04 Identities = 44/182 (24%), Positives = 71/182 (39%), Gaps = 44/182 (24%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWN----- 371 S S D T+ LW+ Q + GH VN V F+ + + S S D S++ W+ Sbjct: 84 SCSSDKTVILWD-VAQGQVVRKFRGHAGKVNCVQFNEEATVIMSGSIDSSIRCWDCRSRR 142 Query: 370 ------------GIT-------------------------GKFVTAFRGHVADVYQISWS 302 GI+ G+ + G + + +S+S Sbjct: 143 PEAIQILDEAKDGISSIKISDHEILAGSVDGNLRRYDLRKGEMCADYLG--SPITCVSFS 200 Query: 301 ADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD--WSPDGEKVVSGGKDRALK 128 DS+ LL+ S DSTL++ D +L + GH + Y +D S V+S +D + Sbjct: 201 QDSQCLLASSLDSTLRLLDKDTGELLGEYTGHQNHSYKLDSCLSEKDTHVLSCSEDGTVC 260 Query: 127 LW 122 W Sbjct: 261 FW 262
>WDR39_HUMAN (O76071) WD-repeat protein 39 (Ciao 1 protein)| Length = 339 Score = 70.9 bits (172), Expect = 2e-12 Identities = 40/119 (33%), Positives = 60/119 (50%), Gaps = 5/119 (4%) Frame = -2 Query: 463 GHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKF--VTAFRGHVADVYQISWSADSR 290 GHQ+ V V +SP G +LASASFD + +W F VT GH +V ++W+ Sbjct: 59 GHQRTVRKVAWSPCGNYLASASFDATTCIWKKNQDDFECVTTLEGHENEVKSVAWAPSGN 118 Query: 289 LLLSGSKDSTLKVWDIRAR---KLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 LL + S+D ++ VW++ + L H +V V W P E + S D +KL+ Sbjct: 119 LLATCSRDKSVWVWEVDEEDEYECVSVLNSHTQDVKHVVWHPSQELLASASYDDTVKLY 177 Score = 65.9 bits (159), Expect = 7e-11 Identities = 43/148 (29%), Positives = 70/148 (47%), Gaps = 10/148 (6%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISK-QPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLW---NG 368 S S D T +W+ + + GH+ V V ++P G LA+ S DKSV +W Sbjct: 78 SASFDATTCIWKKNQDDFECVTTLEGHENEVKSVAWAPSGNLLATCSRDKSVWVWEVDEE 137 Query: 367 ITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQD------LPGH 206 + V+ H DV + W LL S S D T+K++ R+ + D L GH Sbjct: 138 DEYECVSVLNSHTQDVKHVVWHPSQELLASASYDDTVKLY----REEEDDWVCCATLEGH 193 Query: 205 ADEVYAVDWSPDGEKVVSGGKDRALKLW 122 V+++ + P G+++ S DR +++W Sbjct: 194 ESTVWSLAFDPSGQRLASCSDDRTVRIW 221 Score = 54.7 bits (130), Expect = 2e-07 Identities = 32/114 (28%), Positives = 55/114 (48%), Gaps = 10/114 (8%) Frame = -2 Query: 433 FSPDGQWLASASFDKSVKLWNGITGKFV---TAFRGHVADVYQISWSADSRLLLSGSKDS 263 ++P G LAS D+ +++W ++ GH V +++WS L S S D+ Sbjct: 24 WNPAGTLLASCGGDRRIRIWGTEGDSWICKSVLSEGHQRTVRKVAWSPCGNYLASASFDA 83 Query: 262 TLKVWDIRARKLKQD-------LPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 T +W K QD L GH +EV +V W+P G + + +D+++ +W Sbjct: 84 TTCIW-----KKNQDDFECVTTLEGHENEVKSVAWAPSGNLLATCSRDKSVWVW 132 Score = 49.7 bits (117), Expect = 5e-06 Identities = 33/116 (28%), Positives = 59/116 (50%), Gaps = 4/116 (3%) Frame = -2 Query: 529 SDDFTMFLWEPTISKQPK--ARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 S D ++++WE + + + + H + V HV + P + LASAS+D +VKL+ Sbjct: 124 SRDKSVWVWEVDEEDEYECVSVLNSHTQDVKHVVWHPSQELLASASYDDTVKLYREEEDD 183 Query: 355 FV--TAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEV 194 +V GH + V+ +++ + L S S D T+++W +Q LPG+ V Sbjct: 184 WVCCATLEGHESTVWSLAFDPSGQRLASCSDDRTVRIW-------RQYLPGNEQGV 232 Score = 39.7 bits (91), Expect = 0.005 Identities = 31/126 (24%), Positives = 51/126 (40%), Gaps = 25/126 (19%) Frame = -2 Query: 475 ARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLW--------NGI-------TGKFVTAF 341 A + GH+ V + F P GQ LAS S D++V++W G+ + K + Sbjct: 188 ATLEGHESTVWSLAFDPSGQRLASCSDDRTVRIWRQYLPGNEQGVACSGSDPSWKCICTL 247 Query: 340 RG-HVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQD---------LPGHADEVY 191 G H +Y I+W + L + D ++V+ Q H+ +V Sbjct: 248 SGFHSRTIYDIAWCQLTGALATACGDDAIRVFQEDPNSDPQQPTFSLTAHLHQAHSQDVN 307 Query: 190 AVDWSP 173 V W+P Sbjct: 308 CVAWNP 313
>FBXW7_MOUSE (Q8VBV4) F-box/WD-repeat protein 7 (F-box and WD-40 domain protein| 7) (F-box protein FBW7) (F-box protein Fbxw6) (F-box-WD40 repeat protein 6) (SEL-10) Length = 629 Score = 70.5 bits (171), Expect = 3e-12 Identities = 46/138 (33%), Positives = 71/138 (51%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SGSDD T+ +W K + + GH V + + S S D+++K+WN TG+ Sbjct: 318 SGSDDNTLKVWSAVTGKCLRT-LVGHTGGVWSSQMRDN--IIISGSTDRTLKVWNAETGE 374 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 + GH + V + + ++SGS+D+TL+VWDI + L GH V V + Sbjct: 375 CIHTLYGHTSTVRCMH--LHEKRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQY- 431 Query: 175 PDGEKVVSGGKDRALKLW 122 DG +VVSG D +K+W Sbjct: 432 -DGRRVVSGAYDFMVKVW 448 Score = 65.5 bits (158), Expect = 9e-11 Identities = 42/138 (30%), Positives = 71/138 (51%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SGS D T+ +W + + GH V ++ + + S S D ++++W+ TG+ Sbjct: 358 SGSTDRTLKVWNAETGECIHT-LYGHTSTVRCMHLHE--KRVVSGSRDATLRVWDIETGQ 414 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 + GHVA V + + D R ++SG+ D +KVWD L GH + VY++ + Sbjct: 415 CLHVLMGHVAAVRCVQY--DGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQF- 471 Query: 175 PDGEKVVSGGKDRALKLW 122 DG VVSG D ++++W Sbjct: 472 -DGIHVVSGSLDTSIRVW 488 Score = 65.1 bits (157), Expect = 1e-10 Identities = 41/130 (31%), Positives = 62/130 (47%), Gaps = 2/130 (1%) Frame = -2 Query: 505 WEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVA 326 W K PK V+ + F G + S S D ++K+W+ +TGK + GH Sbjct: 287 WRRGELKSPKVLKGHDDHVITCLQFC--GNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTG 344 Query: 325 DVYQISWSADSR--LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVS 152 V WS+ R +++SGS D TLKVW+ + L GH V + ++VVS Sbjct: 345 GV----WSSQMRDNIIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHLHE--KRVVS 398 Query: 151 GGKDRALKLW 122 G +D L++W Sbjct: 399 GSRDATLRVW 408 Score = 62.0 bits (149), Expect = 1e-09 Identities = 41/139 (29%), Positives = 68/139 (48%), Gaps = 1/139 (0%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SG+ DF + +W+P ++ + GH V + F DG + S S D S+++W+ TG Sbjct: 438 SGAYDFMVKVWDPE-TETCLHTLQGHTNRVYSLQF--DGIHVVSGSLDTSIRVWDVETGN 494 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 + GH + +L+SG+ DST+K+WDI+ + Q L G + AV Sbjct: 495 CIHTLTGHQS--LTSGMELKDNILVSGNADSTVKIWDIKTGQCLQTLQGPSKHQSAVTCL 552 Query: 175 PDGEK-VVSGGKDRALKLW 122 + V++ D +KLW Sbjct: 553 QFNKNFVITSSDDGTVKLW 571 Score = 30.0 bits (66), Expect = 4.3 Identities = 19/64 (29%), Positives = 36/64 (56%), Gaps = 2/64 (3%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISK--QPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 362 SG+ D T+ +W+ + Q + HQ V + F+ + ++ ++S D +VKLW+ T Sbjct: 518 SGNADSTVKIWDIKTGQCLQTLQGPSKHQSAVTCLQFNKN--FVITSSDDGTVKLWDLKT 575 Query: 361 GKFV 350 G+F+ Sbjct: 576 GEFI 579
>GBB2_BOVIN (P11017) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 2 (Transducin beta chain 2) (G protein beta 2 subunit) (Fragment) Length = 326 Score = 70.5 bits (171), Expect = 3e-12 Identities = 36/116 (31%), Positives = 61/116 (52%) Frame = -2 Query: 469 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 290 + GH ++ F D Q + S+ D + LW+ TG+ F GH DV +S + D R Sbjct: 125 LPGHTGYLSCCRFLDDNQIITSSG-DTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGR 183 Query: 289 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 +SG+ D+++K+WD+R +Q GH ++ AV + P+G +G D +L+ Sbjct: 184 TFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLF 239 Score = 56.2 bits (134), Expect = 6e-08 Identities = 37/140 (26%), Positives = 65/140 (46%), Gaps = 2/140 (1%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SG+ D ++ LW+ S + GH+ +N V F P+G + S D + +L++ + Sbjct: 187 SGACDASIKLWDVRDS-MCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRADQ 245 Query: 355 FVTAFRGH--VADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 182 + + + + +++S RLLL+G D +WD L GH + V + Sbjct: 246 ELLMYSHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRAGVLAGHDNRVSCLG 305 Query: 181 WSPDGEKVVSGGKDRALKLW 122 + DG V +G D LK+W Sbjct: 306 VTDDGMAVATGSWDSFLKIW 325 Score = 55.8 bits (133), Expect = 7e-08 Identities = 37/143 (25%), Positives = 69/143 (48%), Gaps = 5/143 (3%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 + S D T LW+ +Q GH V + +PDG+ S + D S+KLW+ Sbjct: 145 TSSGDTTCALWDIETGQQTVG-FAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSM 203 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADE-----VY 191 F GH +D+ +++ + +GS D+T +++D+RA Q+L ++ + + Sbjct: 204 CRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRA---DQELLMYSHDNIICGIT 260 Query: 190 AVDWSPDGEKVVSGGKDRALKLW 122 +V +S G +++G D +W Sbjct: 261 SVAFSRSGRLLLAGYDDFNCNIW 283 Score = 53.9 bits (128), Expect = 3e-07 Identities = 25/73 (34%), Positives = 37/73 (50%) Frame = -2 Query: 340 RGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEK 161 RGH+A +Y + W DSRLL+S S+D L +WD +P + V ++P G Sbjct: 38 RGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNF 97 Query: 160 VVSGGKDRALKLW 122 V GG D ++ Sbjct: 98 VACGGLDNICSIY 110 Score = 46.2 bits (108), Expect = 6e-05 Identities = 35/169 (20%), Positives = 63/169 (37%), Gaps = 45/169 (26%) Frame = -2 Query: 493 ISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT---------------- 362 I + + + GH + +++ D + L SAS D + +W+ T Sbjct: 29 IQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMT 88 Query: 361 ------GKFVT-AFRGHVADVYQISWS----------------------ADSRLLLSGSK 269 G FV ++ +Y + D +++ S Sbjct: 89 CAYAPSGNFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIITSSG 148 Query: 268 DSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 D+T +WDI + GH+ +V ++ +PDG VSG D ++KLW Sbjct: 149 DTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLW 197 Score = 40.4 bits (93), Expect = 0.003 Identities = 27/100 (27%), Positives = 46/100 (46%), Gaps = 3/100 (3%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVV---NHVYFSPDGQWLASASFDKSVKLWNGI 365 +GSDD T L++ + + M H ++ V FS G+ L + D + +W+ + Sbjct: 229 TGSDDATCRLFD--LRADQELLMYSHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWDAM 286 Query: 364 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD 245 G GH V + + D + +GS DS LK+W+ Sbjct: 287 KGDRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 326
>TAF5_SCHPO (O13282) Transcription initiation factor TFIID subunit 5| (Transcription initiation factor TFIID 72 kDa subunit) (TAFII-72) Length = 643 Score = 70.5 bits (171), Expect = 3e-12 Identities = 38/138 (27%), Positives = 65/138 (47%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 + S D T LW P GH V+ V F P+ ++ + S DK+ +LW+ G Sbjct: 438 TASHDQTAQLWSCD-HIYPLRVFAGHLSDVDCVTFHPNSAYVLTGSSDKTCRLWDVHRGH 496 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 V F GH V ++ + D + S + + +WDI + + + GH +Y++ +S Sbjct: 497 SVRVFNGHTQPVTAVAIAPDGHTMASADSEGLIHLWDIGTGRRIKTMRGHRGNIYSLSFS 556 Query: 175 PDGEKVVSGGKDRALKLW 122 + +VSGG D ++ W Sbjct: 557 RESTVLVSGGSDCTVRAW 574 Score = 70.1 bits (170), Expect = 4e-12 Identities = 35/99 (35%), Positives = 58/99 (58%), Gaps = 1/99 (1%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARM-TGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITG 359 +GS D T LW+ + + R+ GH + V V +PDG +ASA + + LW+ TG Sbjct: 480 TGSSDKTCRLWD--VHRGHSVRVFNGHTQPVTAVAIAPDGHTMASADSEGLIHLWDIGTG 537 Query: 358 KFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDI 242 + + RGH ++Y +S+S +S +L+SG D T++ WD+ Sbjct: 538 RRIKTMRGHRGNIYSLSFSRESTVLVSGGSDCTVRAWDV 576 Score = 66.2 bits (160), Expect = 5e-11 Identities = 33/117 (28%), Positives = 56/117 (47%) Frame = -2 Query: 472 RMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADS 293 R+ H V FSPD ++L S S D S +LW+ T + A++GH V+ +++ Sbjct: 374 RLLSHSGPVYGTTFSPDNKYLLSCSEDASARLWSVDTKTALVAYKGHTGPVWDVAFGPFG 433 Query: 292 RLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 + S D T ++W + GH +V V + P+ V++G D+ +LW Sbjct: 434 HYFATASHDQTAQLWSCDHIYPLRVFAGHLSDVDCVTFHPNSAYVLTGSSDKTCRLW 490 Score = 47.4 bits (111), Expect = 3e-05 Identities = 29/122 (23%), Positives = 51/122 (41%), Gaps = 13/122 (10%) Frame = -2 Query: 448 VNHVYFSPDGQWLASASFDKSVKLWNGITGK-------------FVTAFRGHVADVYQIS 308 +N FSPD +A + ++LW+ K H VY + Sbjct: 327 MNCAEFSPDSTMIACGFQESYIRLWSIKADKKSLPKSTSVEDSDGSVRLLSHSGPVYGTT 386 Query: 307 WSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALK 128 +S D++ LLS S+D++ ++W + + GH V+ V + P G + D+ + Sbjct: 387 FSPDNKYLLSCSEDASARLWSVDTKTALVAYKGHTGPVWDVAFGPFGHYFATASHDQTAQ 446 Query: 127 LW 122 LW Sbjct: 447 LW 448 Score = 32.0 bits (71), Expect = 1.1 Identities = 21/90 (23%), Positives = 38/90 (42%), Gaps = 12/90 (13%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWN----- 371 S + + LW+ ++ K M GH+ + + FS + L S D +V+ W+ Sbjct: 522 SADSEGLIHLWDIGTGRRIKT-MRGHRGNIYSLSFSRESTVLVSGGSDCTVRAWDVFKTN 580 Query: 370 -------GITGKFVTAFRGHVADVYQISWS 302 +TG VT F + +++WS Sbjct: 581 YNNPVSSSLTGSVVTPFSAKTSTFNEVNWS 610
>COPB2_CAEEL (Q20168) Probable coatomer subunit beta' (Beta'-coat protein)| (Beta'-COP) Length = 1000 Score = 70.5 bits (171), Expect = 3e-12 Identities = 40/141 (28%), Positives = 68/141 (48%), Gaps = 3/141 (2%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSP-DGQWLASASFDKSVKLWNGITG 359 S SDD + +W+ K GH V + +P D A+AS DK+VK+W + Sbjct: 116 SSSDDMLVKMWDWDNKWAMKQSFEGHTHYVMQIAINPKDNNTFATASLDKTVKVWQFGSN 175 Query: 358 KFVTAFRGHVADVYQISW--SADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAV 185 GH V + + + ++SG+ D +K+WD + + Q L GHA V +V Sbjct: 176 VPNFTLEGHEKGVNCVDYYHGGEKPYIISGADDHLVKIWDYQNKTCVQTLDGHAQNVSSV 235 Query: 184 DWSPDGEKVVSGGKDRALKLW 122 + P+ +++G +D ++LW Sbjct: 236 CFHPELPLIITGSEDSTVRLW 256 Score = 50.8 bits (120), Expect = 2e-06 Identities = 34/134 (25%), Positives = 66/134 (49%), Gaps = 2/134 (1%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQ--WLASASFDKSVKLWNGIT 362 + S D T+ +W+ S P + GH+K VN V + G+ ++ S + D VK+W+ Sbjct: 160 TASLDKTVKVWQFG-SNVPNFTLEGHEKGVNCVDYYHGGEKPYIISGADDHLVKIWDYQN 218 Query: 361 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 182 V GH +V + + + L+++GS+DST+++W + + L + V+ + Sbjct: 219 KTCVQTLDGHAQNVSSVCFHPELPLIITGSEDSTVRLWHANTYRQEHTLNYGLERVWCIQ 278 Query: 181 WSPDGEKVVSGGKD 140 + G ++ G D Sbjct: 279 -AQKGANTIAIGYD 291 Score = 40.4 bits (93), Expect = 0.003 Identities = 26/119 (21%), Positives = 50/119 (42%) Frame = -2 Query: 478 KARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSA 299 K ++ V V P WL +A ++ +V +WN T V +F V + Sbjct: 8 KRKLLARSDRVKCVDLHPVETWLLAALYNGNVHIWNYETQTLVKSFEVCDVPVRAAKFVP 67 Query: 298 DSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 +++GS D ++V++ + H+D + ++ P V+S D +K+W Sbjct: 68 RKSWVVTGSDDMHIRVFNYNTLERVHQFEAHSDYLRSLVVHPTLPYVISSSDDMLVKMW 126
>SCONB_EMENI (Q00659) Sulfur metabolite repression control protein| Length = 678 Score = 70.5 bits (171), Expect = 3e-12 Identities = 44/138 (31%), Positives = 70/138 (50%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 +GS D T+ +W+ ++ + + GH+ + + F D L S S D+++K+WN TG+ Sbjct: 364 TGSYDTTIKIWDTETGEELRT-LRGHESGIRCLQF--DDTKLISGSMDRTIKVWNWRTGE 420 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 ++ + GH V I D+ +L SGS D T+K+W+ K L GH D V AV Sbjct: 421 CISTYTGHRGGV--IGLHFDASILASGSVDKTVKIWNFE-DKSTFSLRGHTDWVNAVRVD 477 Query: 175 PDGEKVVSGGKDRALKLW 122 V S D ++LW Sbjct: 478 TSSRTVFSASDDCTVRLW 495 Score = 59.3 bits (142), Expect = 7e-09 Identities = 31/97 (31%), Positives = 53/97 (54%) Frame = -2 Query: 412 LASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRAR 233 LA+ S+D ++K+W+ TG+ + RGH + + + + D L+SGS D T+KVW+ R Sbjct: 362 LATGSYDTTIKIWDTETGEELRTLRGHESGIRCLQF--DDTKLISGSMDRTIKVWNWRTG 419 Query: 232 KLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 + GH V + + D + SG D+ +K+W Sbjct: 420 ECISTYTGHRGGVIGLHF--DASILASGSVDKTVKIW 454 Score = 57.8 bits (138), Expect = 2e-08 Identities = 39/117 (33%), Positives = 58/117 (49%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SGS D T+ +W + + TGH+ V ++F D LAS S DK+VK+WN K Sbjct: 404 SGSMDRTIKVWNWRTG-ECISTYTGHRGGVIGLHF--DASILASGSVDKTVKIWN-FEDK 459 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAV 185 + RGH V + SR + S S D T+++WD+ + + GH +V V Sbjct: 460 STFSLRGHTDWVNAVRVDTSSRTVFSASDDCTVRLWDLDTKTCIRTFHGHVGQVQQV 516 Score = 54.3 bits (129), Expect = 2e-07 Identities = 24/99 (24%), Positives = 56/99 (56%) Frame = -2 Query: 418 QWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIR 239 +++ +++ D +++LW TG+ + F GH+ V+ + AD+ ++SG++D +K+WD R Sbjct: 580 RYMVTSALDSTIRLWETTTGRCLRTFFGHLEGVWALG--ADTLRIVSGAEDRMIKIWDPR 637 Query: 238 ARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 K ++ GH+ V + + +G +D ++++ Sbjct: 638 TGKCERTFTGHSGPVTCIGLG--DSRFATGSEDCEVRMY 674 Score = 48.5 bits (114), Expect = 1e-05 Identities = 23/77 (29%), Positives = 42/77 (54%) Frame = -2 Query: 352 VTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSP 173 + F+GH V + + + +L +GS D+T+K+WD + + L GH + + + Sbjct: 342 IKTFKGHTNGVMCLQF--EDNILATGSYDTTIKIWDTETGEELRTLRGHESGIRCLQF-- 397 Query: 172 DGEKVVSGGKDRALKLW 122 D K++SG DR +K+W Sbjct: 398 DDTKLISGSMDRTIKVW 414 Score = 41.2 bits (95), Expect = 0.002 Identities = 18/61 (29%), Positives = 37/61 (60%) Frame = -2 Query: 304 SADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKL 125 +A R +++ + DST+++W+ + + GH + V+A+ D ++VSG +DR +K+ Sbjct: 576 AAPPRYMVTSALDSTIRLWETTTGRCLRTFFGHLEGVWAL--GADTLRIVSGAEDRMIKI 633 Query: 124 W 122 W Sbjct: 634 W 634
>FBXW7_HUMAN (Q969H0) F-box/WD-repeat protein 7 (F-box and WD-40 domain protein| 7) (F-box protein FBX30) (hCdc4) (Archipelago homolog) (hAgo) (SEL-10) Length = 707 Score = 70.5 bits (171), Expect = 3e-12 Identities = 46/138 (33%), Positives = 71/138 (51%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SGSDD T+ +W K + + GH V + + S S D+++K+WN TG+ Sbjct: 396 SGSDDNTLKVWSAVTGKCLRT-LVGHTGGVWSSQMRDN--IIISGSTDRTLKVWNAETGE 452 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 + GH + V + + ++SGS+D+TL+VWDI + L GH V V + Sbjct: 453 CIHTLYGHTSTVRCMH--LHEKRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQY- 509 Query: 175 PDGEKVVSGGKDRALKLW 122 DG +VVSG D +K+W Sbjct: 510 -DGRRVVSGAYDFMVKVW 526 Score = 65.5 bits (158), Expect = 9e-11 Identities = 42/138 (30%), Positives = 71/138 (51%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SGS D T+ +W + + GH V ++ + + S S D ++++W+ TG+ Sbjct: 436 SGSTDRTLKVWNAETGECIHT-LYGHTSTVRCMHLHE--KRVVSGSRDATLRVWDIETGQ 492 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 + GHVA V + + D R ++SG+ D +KVWD L GH + VY++ + Sbjct: 493 CLHVLMGHVAAVRCVQY--DGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQF- 549 Query: 175 PDGEKVVSGGKDRALKLW 122 DG VVSG D ++++W Sbjct: 550 -DGIHVVSGSLDTSIRVW 566 Score = 65.1 bits (157), Expect = 1e-10 Identities = 41/130 (31%), Positives = 62/130 (47%), Gaps = 2/130 (1%) Frame = -2 Query: 505 WEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVA 326 W K PK V+ + F G + S S D ++K+W+ +TGK + GH Sbjct: 365 WRRGELKSPKVLKGHDDHVITCLQFC--GNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTG 422 Query: 325 DVYQISWSADSR--LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVS 152 V WS+ R +++SGS D TLKVW+ + L GH V + ++VVS Sbjct: 423 GV----WSSQMRDNIIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHLHE--KRVVS 476 Query: 151 GGKDRALKLW 122 G +D L++W Sbjct: 477 GSRDATLRVW 486 Score = 61.6 bits (148), Expect = 1e-09 Identities = 41/141 (29%), Positives = 70/141 (49%), Gaps = 3/141 (2%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SG+ DF + +W+P ++ + GH V + F DG + S S D S+++W+ TG Sbjct: 516 SGAYDFMVKVWDPE-TETCLHTLQGHTNRVYSLQF--DGIHVVSGSLDTSIRVWDVETGN 572 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPG---HADEVYAV 185 + GH + +L+SG+ DST+K+WDI+ + Q L G H V + Sbjct: 573 CIHTLTGHQS--LTSGMELKDNILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCL 630 Query: 184 DWSPDGEKVVSGGKDRALKLW 122 ++ + V++ D +KLW Sbjct: 631 QFNKN--FVITSSDDGTVKLW 649 Score = 29.6 bits (65), Expect = 5.6 Identities = 19/64 (29%), Positives = 35/64 (54%), Gaps = 2/64 (3%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISK--QPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 362 SG+ D T+ +W+ + Q HQ V + F+ + ++ ++S D +VKLW+ T Sbjct: 596 SGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKN--FVITSSDDGTVKLWDLKT 653 Query: 361 GKFV 350 G+F+ Sbjct: 654 GEFI 657
>GBB2_RAT (P54313) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 2 (Transducin beta chain 2) (G protein beta 2 subunit) Length = 339 Score = 70.5 bits (171), Expect = 3e-12 Identities = 36/116 (31%), Positives = 61/116 (52%) Frame = -2 Query: 469 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 290 + GH ++ F D Q + S+ D + LW+ TG+ F GH DV +S + D R Sbjct: 138 LPGHTGYLSCCRFLDDNQIITSSG-DTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGR 196 Query: 289 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 +SG+ D+++K+WD+R +Q GH ++ AV + P+G +G D +L+ Sbjct: 197 TFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLF 252 Score = 56.2 bits (134), Expect = 6e-08 Identities = 37/140 (26%), Positives = 65/140 (46%), Gaps = 2/140 (1%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SG+ D ++ LW+ S + GH+ +N V F P+G + S D + +L++ + Sbjct: 200 SGACDASIKLWDVRDS-MCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRADQ 258 Query: 355 FVTAFRGH--VADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 182 + + + + +++S RLLL+G D +WD L GH + V + Sbjct: 259 ELLMYSHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRAGVLAGHDNRVSCLG 318 Query: 181 WSPDGEKVVSGGKDRALKLW 122 + DG V +G D LK+W Sbjct: 319 VTDDGMAVATGSWDSFLKIW 338 Score = 55.8 bits (133), Expect = 7e-08 Identities = 37/143 (25%), Positives = 69/143 (48%), Gaps = 5/143 (3%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 + S D T LW+ +Q GH V + +PDG+ S + D S+KLW+ Sbjct: 158 TSSGDTTCALWDIETGQQTVG-FAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSM 216 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADE-----VY 191 F GH +D+ +++ + +GS D+T +++D+RA Q+L ++ + + Sbjct: 217 CRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRA---DQELLMYSHDNIICGIT 273 Query: 190 AVDWSPDGEKVVSGGKDRALKLW 122 +V +S G +++G D +W Sbjct: 274 SVAFSRSGRLLLAGYDDFNCNIW 296 Score = 53.9 bits (128), Expect = 3e-07 Identities = 25/73 (34%), Positives = 37/73 (50%) Frame = -2 Query: 340 RGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEK 161 RGH+A +Y + W DSRLL+S S+D L +WD +P + V ++P G Sbjct: 51 RGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNF 110 Query: 160 VVSGGKDRALKLW 122 V GG D ++ Sbjct: 111 VACGGLDNICSIY 123 Score = 46.2 bits (108), Expect = 6e-05 Identities = 35/169 (20%), Positives = 63/169 (37%), Gaps = 45/169 (26%) Frame = -2 Query: 493 ISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT---------------- 362 I + + + GH + +++ D + L SAS D + +W+ T Sbjct: 42 IQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMT 101 Query: 361 ------GKFVT-AFRGHVADVYQISWS----------------------ADSRLLLSGSK 269 G FV ++ +Y + D +++ S Sbjct: 102 CAYAPSGNFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIITSSG 161 Query: 268 DSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 D+T +WDI + GH+ +V ++ +PDG VSG D ++KLW Sbjct: 162 DTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLW 210 Score = 40.4 bits (93), Expect = 0.003 Identities = 27/100 (27%), Positives = 46/100 (46%), Gaps = 3/100 (3%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVV---NHVYFSPDGQWLASASFDKSVKLWNGI 365 +GSDD T L++ + + M H ++ V FS G+ L + D + +W+ + Sbjct: 242 TGSDDATCRLFD--LRADQELLMYSHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWDAM 299 Query: 364 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD 245 G GH V + + D + +GS DS LK+W+ Sbjct: 300 KGDRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 339
>GBB2_MOUSE (P62880) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 2 (Transducin beta chain 2) (G protein beta 2 subunit) Length = 339 Score = 70.5 bits (171), Expect = 3e-12 Identities = 36/116 (31%), Positives = 61/116 (52%) Frame = -2 Query: 469 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 290 + GH ++ F D Q + S+ D + LW+ TG+ F GH DV +S + D R Sbjct: 138 LPGHTGYLSCCRFLDDNQIITSSG-DTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGR 196 Query: 289 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 +SG+ D+++K+WD+R +Q GH ++ AV + P+G +G D +L+ Sbjct: 197 TFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLF 252 Score = 56.2 bits (134), Expect = 6e-08 Identities = 37/140 (26%), Positives = 65/140 (46%), Gaps = 2/140 (1%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SG+ D ++ LW+ S + GH+ +N V F P+G + S D + +L++ + Sbjct: 200 SGACDASIKLWDVRDS-MCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRADQ 258 Query: 355 FVTAFRGH--VADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 182 + + + + +++S RLLL+G D +WD L GH + V + Sbjct: 259 ELLMYSHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRAGVLAGHDNRVSCLG 318 Query: 181 WSPDGEKVVSGGKDRALKLW 122 + DG V +G D LK+W Sbjct: 319 VTDDGMAVATGSWDSFLKIW 338 Score = 55.8 bits (133), Expect = 7e-08 Identities = 37/143 (25%), Positives = 69/143 (48%), Gaps = 5/143 (3%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 + S D T LW+ +Q GH V + +PDG+ S + D S+KLW+ Sbjct: 158 TSSGDTTCALWDIETGQQTVG-FAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSM 216 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADE-----VY 191 F GH +D+ +++ + +GS D+T +++D+RA Q+L ++ + + Sbjct: 217 CRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRA---DQELLMYSHDNIICGIT 273 Query: 190 AVDWSPDGEKVVSGGKDRALKLW 122 +V +S G +++G D +W Sbjct: 274 SVAFSRSGRLLLAGYDDFNCNIW 296 Score = 53.9 bits (128), Expect = 3e-07 Identities = 25/73 (34%), Positives = 37/73 (50%) Frame = -2 Query: 340 RGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEK 161 RGH+A +Y + W DSRLL+S S+D L +WD +P + V ++P G Sbjct: 51 RGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNF 110 Query: 160 VVSGGKDRALKLW 122 V GG D ++ Sbjct: 111 VACGGLDNICSIY 123 Score = 46.2 bits (108), Expect = 6e-05 Identities = 35/169 (20%), Positives = 63/169 (37%), Gaps = 45/169 (26%) Frame = -2 Query: 493 ISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT---------------- 362 I + + + GH + +++ D + L SAS D + +W+ T Sbjct: 42 IQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMT 101 Query: 361 ------GKFVT-AFRGHVADVYQISWS----------------------ADSRLLLSGSK 269 G FV ++ +Y + D +++ S Sbjct: 102 CAYAPSGNFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIITSSG 161 Query: 268 DSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 D+T +WDI + GH+ +V ++ +PDG VSG D ++KLW Sbjct: 162 DTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLW 210 Score = 40.4 bits (93), Expect = 0.003 Identities = 27/100 (27%), Positives = 46/100 (46%), Gaps = 3/100 (3%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVV---NHVYFSPDGQWLASASFDKSVKLWNGI 365 +GSDD T L++ + + M H ++ V FS G+ L + D + +W+ + Sbjct: 242 TGSDDATCRLFD--LRADQELLMYSHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWDAM 299 Query: 364 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD 245 G GH V + + D + +GS DS LK+W+ Sbjct: 300 KGDRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 339
>GBB2_HUMAN (P62879) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 2 (Transducin beta chain 2) (G protein beta 2 subunit) Length = 339 Score = 70.5 bits (171), Expect = 3e-12 Identities = 36/116 (31%), Positives = 61/116 (52%) Frame = -2 Query: 469 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 290 + GH ++ F D Q + S+ D + LW+ TG+ F GH DV +S + D R Sbjct: 138 LPGHTGYLSCCRFLDDNQIITSSG-DTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGR 196 Query: 289 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 +SG+ D+++K+WD+R +Q GH ++ AV + P+G +G D +L+ Sbjct: 197 TFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLF 252 Score = 56.2 bits (134), Expect = 6e-08 Identities = 37/140 (26%), Positives = 65/140 (46%), Gaps = 2/140 (1%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SG+ D ++ LW+ S + GH+ +N V F P+G + S D + +L++ + Sbjct: 200 SGACDASIKLWDVRDS-MCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRADQ 258 Query: 355 FVTAFRGH--VADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 182 + + + + +++S RLLL+G D +WD L GH + V + Sbjct: 259 ELLMYSHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRAGVLAGHDNRVSCLG 318 Query: 181 WSPDGEKVVSGGKDRALKLW 122 + DG V +G D LK+W Sbjct: 319 VTDDGMAVATGSWDSFLKIW 338 Score = 55.8 bits (133), Expect = 7e-08 Identities = 37/143 (25%), Positives = 69/143 (48%), Gaps = 5/143 (3%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 + S D T LW+ +Q GH V + +PDG+ S + D S+KLW+ Sbjct: 158 TSSGDTTCALWDIETGQQTVG-FAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSM 216 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADE-----VY 191 F GH +D+ +++ + +GS D+T +++D+RA Q+L ++ + + Sbjct: 217 CRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRA---DQELLMYSHDNIICGIT 273 Query: 190 AVDWSPDGEKVVSGGKDRALKLW 122 +V +S G +++G D +W Sbjct: 274 SVAFSRSGRLLLAGYDDFNCNIW 296 Score = 53.9 bits (128), Expect = 3e-07 Identities = 25/73 (34%), Positives = 37/73 (50%) Frame = -2 Query: 340 RGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEK 161 RGH+A +Y + W DSRLL+S S+D L +WD +P + V ++P G Sbjct: 51 RGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNF 110 Query: 160 VVSGGKDRALKLW 122 V GG D ++ Sbjct: 111 VACGGLDNICSIY 123 Score = 46.2 bits (108), Expect = 6e-05 Identities = 35/169 (20%), Positives = 63/169 (37%), Gaps = 45/169 (26%) Frame = -2 Query: 493 ISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT---------------- 362 I + + + GH + +++ D + L SAS D + +W+ T Sbjct: 42 IQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMT 101 Query: 361 ------GKFVT-AFRGHVADVYQISWS----------------------ADSRLLLSGSK 269 G FV ++ +Y + D +++ S Sbjct: 102 CAYAPSGNFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIITSSG 161 Query: 268 DSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 D+T +WDI + GH+ +V ++ +PDG VSG D ++KLW Sbjct: 162 DTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLW 210 Score = 40.4 bits (93), Expect = 0.003 Identities = 27/100 (27%), Positives = 46/100 (46%), Gaps = 3/100 (3%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVV---NHVYFSPDGQWLASASFDKSVKLWNGI 365 +GSDD T L++ + + M H ++ V FS G+ L + D + +W+ + Sbjct: 242 TGSDDATCRLFD--LRADQELLMYSHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWDAM 299 Query: 364 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD 245 G GH V + + D + +GS DS LK+W+ Sbjct: 300 KGDRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 339
>COPB2_DROME (O62621) Coatomer subunit beta' (Beta'-coat protein) (Beta'-COP)| Length = 914 Score = 70.1 bits (170), Expect = 4e-12 Identities = 42/141 (29%), Positives = 68/141 (48%), Gaps = 3/141 (2%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSP-DGQWLASASFDKSVKLWNGITG 359 + SDD + LW + GH V + F+P D ASAS D++VK+W + Sbjct: 116 TSSDDMLIKLWNWEKMWACQRVFEGHTHYVMQIVFNPKDNNTFASASLDRTVKVWQLGSN 175 Query: 358 KFVTAFRGHVADVYQISW--SADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAV 185 GH V + + D L+SG+ D +K+WD + + Q L GHA + AV Sbjct: 176 FANFTLEGHEKGVNCVDYYHGGDKPYLISGADDRLVKIWDYQNKTCVQTLEGHAQNISAV 235 Query: 184 DWSPDGEKVVSGGKDRALKLW 122 + P+ V++G +D +++W Sbjct: 236 CFHPELPIVLTGSEDGTVRIW 256 Score = 50.4 bits (119), Expect = 3e-06 Identities = 37/134 (27%), Positives = 65/134 (48%), Gaps = 2/134 (1%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHV--YFSPDGQWLASASFDKSVKLWNGIT 362 S S D T+ +W+ S + GH+K VN V Y D +L S + D+ VK+W+ Sbjct: 160 SASLDRTVKVWQLG-SNFANFTLEGHEKGVNCVDYYHGGDKPYLISGADDRLVKIWDYQN 218 Query: 361 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 182 V GH ++ + + + ++L+GS+D T+++W +L+ L + V+ + Sbjct: 219 KTCVQTLEGHAQNISAVCFHPELPIVLTGSEDGTVRIWHSGTYRLETCLNYGFERVWTIS 278 Query: 181 WSPDGEKVVSGGKD 140 S G V+ G D Sbjct: 279 -SMRGTNNVALGYD 291 Score = 40.0 bits (92), Expect = 0.004 Identities = 27/119 (22%), Positives = 47/119 (39%) Frame = -2 Query: 478 KARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSA 299 K R+T V V P W+ A ++ V + N + V F V + A Sbjct: 8 KRRLTSRSDRVKCVDLHPAEPWMLCALYNGHVHIMNYENQQMVKDFEVCDVPVRSARFVA 67 Query: 298 DSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 +L+GS D ++V++ + H+D + + P V++ D +KLW Sbjct: 68 RKNWILTGSDDMQIRVFNYNTLEKVHSFEAHSDYLRCIAVHPTQPLVLTSSDDMLIKLW 126
>A16L1_PONPY (Q5RAC9) Autophagy-related protein 16-1 (APG16-like 1)| Length = 607 Score = 70.1 bits (170), Expect = 4e-12 Identities = 38/115 (33%), Positives = 58/115 (50%), Gaps = 2/115 (1%) Frame = -2 Query: 460 HQKVVNHVYFSPDGQWLASASFDKSVKLWN--GITGKFVTAFRGHVADVYQISWSADSRL 287 H VN V FSP + LA+ D+ VKLW G +F + G A + I + + Sbjct: 321 HDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAGSY 380 Query: 286 LLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 LL+ S D ++W + +L+ L GH+ +V + + D ++VSG DR LK W Sbjct: 381 LLAASNDFASRIWTVDDSRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKHW 435 Score = 51.6 bits (122), Expect = 1e-06 Identities = 36/141 (25%), Positives = 67/141 (47%), Gaps = 3/141 (2%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISK-QPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITG 359 +G D + LWE K + K ++G + + F G +L +AS D + ++W Sbjct: 339 TGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAGSYLLAASNDFASRIWTVDDS 398 Query: 358 KFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARK-LKQDLPGHA-DEVYAV 185 + GH V + D+ ++SGS D TLK WD+R++ +K G + +++ Sbjct: 399 RLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKHWDLRSKVCIKTVFAGSSCNDIVCT 458 Query: 184 DWSPDGEKVVSGGKDRALKLW 122 + + V+SG D+ ++ W Sbjct: 459 E-----QCVMSGHFDKKIRFW 474 Score = 43.9 bits (102), Expect = 3e-04 Identities = 39/142 (27%), Positives = 62/142 (43%), Gaps = 4/142 (2%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SGS D T+ W+ K G N + + Q + S FDK ++ W+ I + Sbjct: 425 SGSHDRTLKHWDLRSKVCIKTVFAGSS--CNDIVCTE--QCVMSGHFDKKIRFWD-IRSE 479 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQ--DLPGH--ADEVYA 188 + + + + + + LLS S+D LKV D+R +KQ PG + Sbjct: 480 SIVREMELLGKITALDLNPERTELLSCSRDDLLKVIDLRTNAIKQTFSAPGFKCGSDWTR 539 Query: 187 VDWSPDGEKVVSGGKDRALKLW 122 V +SPDG V +G + +L W Sbjct: 540 VVFSPDGSYVAAGSAEGSLYTW 561 Score = 40.4 bits (93), Expect = 0.003 Identities = 20/76 (26%), Positives = 38/76 (50%), Gaps = 2/76 (2%) Frame = -2 Query: 343 FRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARK--LKQDLPGHADEVYAVDWSPD 170 F H +V + +S SRLL +G D +K+W++ K K L G + ++++ Sbjct: 318 FDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSA 377 Query: 169 GEKVVSGGKDRALKLW 122 G +++ D A ++W Sbjct: 378 GSYLLAASNDFASRIW 393 Score = 39.7 bits (91), Expect = 0.005 Identities = 22/70 (31%), Positives = 36/70 (51%), Gaps = 1/70 (1%) Frame = -2 Query: 328 ADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPG-HADEVYAVDWSPDGEKVVS 152 +D ++ +S D + +GS + +L W + K+++ L H+ + AV WSP G VVS Sbjct: 535 SDWTRVVFSPDGSYVAAGSAEGSLYTWSVLTGKVEKVLSKQHSSSINAVAWSPSGLHVVS 594 Query: 151 GGKDRALKLW 122 K LW Sbjct: 595 VDKGCKAVLW 604 Score = 38.9 bits (89), Expect = 0.009 Identities = 19/65 (29%), Positives = 34/65 (52%), Gaps = 1/65 (1%) Frame = -2 Query: 439 VYFSPDGQWLASASFDKSVKLWNGITGKFVTAF-RGHVADVYQISWSADSRLLLSGSKDS 263 V FSPDG ++A+ S + S+ W+ +TGK + H + + ++WS ++S K Sbjct: 540 VVFSPDGSYVAAGSAEGSLYTWSVLTGKVEKVLSKQHSSSINAVAWSPSGLHVVSVDKGC 599 Query: 262 TLKVW 248 +W Sbjct: 600 KAVLW 604
>GBB3_RAT (P52287) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 3 (Transducin beta chain 3) Length = 340 Score = 70.1 bits (170), Expect = 4e-12 Identities = 32/101 (31%), Positives = 58/101 (57%) Frame = -2 Query: 424 DGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD 245 D + ++S D + LW+ TG+ T F GH D ++ S D +L +SG+ D++ K+WD Sbjct: 153 DDNNIVTSSGDTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDYKLFISGACDASAKLWD 212 Query: 244 IRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 +R +Q GH ++ A+ + P+GE + +G D + +L+ Sbjct: 213 VREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLF 253 Score = 61.6 bits (148), Expect = 1e-09 Identities = 39/140 (27%), Positives = 68/140 (48%), Gaps = 2/140 (1%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SG+ D + LW+ + TGH+ +N + F P+G+ + + S D S +L++ + Sbjct: 201 SGACDASAKLWDVR-EGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQ 259 Query: 355 FVTAFRGH--VADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 182 +TA+ + + +++S RLL +G D VWD + L GH + V + Sbjct: 260 ELTAYSHESIICGITSVAFSLSGRLLFAGYDDFNCNVWDSLKCERVGVLSGHDNRVSCLG 319 Query: 181 WSPDGEKVVSGGKDRALKLW 122 + DG V +G D LK+W Sbjct: 320 VTADGMAVATGSWDSFLKIW 339 Score = 56.2 bits (134), Expect = 6e-08 Identities = 40/148 (27%), Positives = 69/148 (46%), Gaps = 5/148 (3%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 + S D T LW+ +Q K GH + SPD + S + D S KLW+ G Sbjct: 159 TSSGDTTCALWDIETGQQ-KTVFVGHTGDCMSLAVSPDYKLFISGACDASAKLWDVREGT 217 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADE-----VY 191 F GH +D+ I + + + +GS D++ +++D+RA Q+L ++ E + Sbjct: 218 CRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRA---DQELTAYSHESIICGIT 274 Query: 190 AVDWSPDGEKVVSGGKDRALKLWMN*AC 107 +V +S G + +G D +W + C Sbjct: 275 SVAFSLSGRLLFAGYDDFNCNVWDSLKC 302 Score = 53.9 bits (128), Expect = 3e-07 Identities = 25/73 (34%), Positives = 38/73 (52%) Frame = -2 Query: 340 RGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEK 161 RGH+A +Y + W+ DS+LL+S S+D L VWD +P + V ++P G Sbjct: 52 RGHLAKIYAMHWATDSKLLVSASQDGKLIVWDTYTTNKVHAIPLRSSWVMTCAYAPSGNF 111 Query: 160 VVSGGKDRALKLW 122 V GG D ++ Sbjct: 112 VACGGLDNMCSIY 124 Score = 38.5 bits (88), Expect = 0.012 Identities = 27/100 (27%), Positives = 49/100 (49%), Gaps = 3/100 (3%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVV---NHVYFSPDGQWLASASFDKSVKLWNGI 365 +GSDD + L++ ++ A H+ ++ V FS G+ L + D + +W+ + Sbjct: 243 TGSDDASCRLFDLRADQELTAY--SHESIICGITSVAFSLSGRLLFAGYDDFNCNVWDSL 300 Query: 364 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD 245 + V GH V + +AD + +GS DS LK+W+ Sbjct: 301 KCERVGVLSGHDNRVSCLGVTADGMAVATGSWDSFLKIWN 340 Score = 38.1 bits (87), Expect = 0.016 Identities = 35/169 (20%), Positives = 64/169 (37%), Gaps = 45/169 (26%) Frame = -2 Query: 493 ISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT---------------- 362 + + + + GH + ++++ D + L SAS D + +W+ T Sbjct: 43 VQMRTRRTLRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDTYTTNKVHAIPLRSSWVMT 102 Query: 361 ------GKFVT--------------AFRGHVADVYQISWSA---------DSRLLLSGSK 269 G FV + G+V ++S D +++ S Sbjct: 103 CAYAPSGNFVACGGLDNMCSIYSLKSREGNVKVSRELSAHTGYLSCCRFLDDNNIVTSSG 162 Query: 268 DSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 D+T +WDI + K GH + ++ SPD + +SG D + KLW Sbjct: 163 DTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDYKLFISGACDASAKLW 211
>GBB3_MOUSE (Q61011) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 3 (Transducin beta chain 3) Length = 340 Score = 70.1 bits (170), Expect = 4e-12 Identities = 32/101 (31%), Positives = 58/101 (57%) Frame = -2 Query: 424 DGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD 245 D + ++S D + LW+ TG+ T F GH D ++ S D +L +SG+ D++ K+WD Sbjct: 153 DDNNIVTSSGDTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDYKLFISGACDASAKLWD 212 Query: 244 IRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 +R +Q GH ++ A+ + P+GE + +G D + +L+ Sbjct: 213 VREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLF 253 Score = 61.6 bits (148), Expect = 1e-09 Identities = 39/140 (27%), Positives = 68/140 (48%), Gaps = 2/140 (1%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SG+ D + LW+ + TGH+ +N + F P+G+ + + S D S +L++ + Sbjct: 201 SGACDASAKLWDVR-EGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQ 259 Query: 355 FVTAFRGH--VADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 182 +TA+ + + +++S RLL +G D VWD + L GH + V + Sbjct: 260 ELTAYSQESIICGITSVAFSLSGRLLFAGYDDFNCNVWDSLKCERVGILSGHDNRVSCLG 319 Query: 181 WSPDGEKVVSGGKDRALKLW 122 + DG V +G D LK+W Sbjct: 320 VTADGMAVATGSWDSFLKIW 339 Score = 56.6 bits (135), Expect = 4e-08 Identities = 40/148 (27%), Positives = 69/148 (46%), Gaps = 5/148 (3%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 + S D T LW+ +Q K GH + SPD + S + D S KLW+ G Sbjct: 159 TSSGDTTCALWDIETGQQ-KTVFVGHTGDCMSLAVSPDYKLFISGACDASAKLWDVREGT 217 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADE-----VY 191 F GH +D+ I + + + +GS D++ +++D+RA Q+L ++ E + Sbjct: 218 CRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRA---DQELTAYSQESIICGIT 274 Query: 190 AVDWSPDGEKVVSGGKDRALKLWMN*AC 107 +V +S G + +G D +W + C Sbjct: 275 SVAFSLSGRLLFAGYDDFNCNVWDSLKC 302 Score = 53.9 bits (128), Expect = 3e-07 Identities = 25/73 (34%), Positives = 38/73 (52%) Frame = -2 Query: 340 RGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEK 161 RGH+A +Y + W+ DS+LL+S S+D L VWD +P + V ++P G Sbjct: 52 RGHLAKIYAMHWATDSKLLVSASQDGKLIVWDTYTTNKVHAIPLRSSWVMTCAYAPSGNF 111 Query: 160 VVSGGKDRALKLW 122 V GG D ++ Sbjct: 112 VACGGLDNMCSIY 124 Score = 38.1 bits (87), Expect = 0.016 Identities = 26/128 (20%), Positives = 56/128 (43%), Gaps = 4/128 (3%) Frame = -2 Query: 493 ISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQ 314 + + + + GH + ++++ D + L SAS D + +W+ T V A + V Sbjct: 43 VQMRTRRTLRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDTYTTNKVHAIPLRSSWVMT 102 Query: 313 ISWSADSRLLLSGSKDSTLKVWDIRAR----KLKQDLPGHADEVYAVDWSPDGEKVVSGG 146 +++ + G D+ ++++++R K+ ++L H + + D V S G Sbjct: 103 CAYAPSGNFVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDNNIVTSSG 162 Query: 145 KDRALKLW 122 D LW Sbjct: 163 -DTTCALW 169 Score = 35.4 bits (80), Expect = 0.10 Identities = 20/68 (29%), Positives = 34/68 (50%) Frame = -2 Query: 448 VNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSK 269 + V FS G+ L + D + +W+ + + V GH V + +AD + +GS Sbjct: 273 ITSVAFSLSGRLLFAGYDDFNCNVWDSLKCERVGILSGHDNRVSCLGVTADGMAVATGSW 332 Query: 268 DSTLKVWD 245 DS LK+W+ Sbjct: 333 DSFLKIWN 340 Score = 34.7 bits (78), Expect = 0.17 Identities = 16/55 (29%), Positives = 32/55 (58%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWN 371 +G DDF +W+ ++ + ++GH V+ + + DG +A+ S+D +K+WN Sbjct: 287 AGYDDFNCNVWD-SLKCERVGILSGHDNRVSCLGVTADGMAVATGSWDSFLKIWN 340
>GBB3_CANFA (P79147) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 3 (Transducin beta chain 3) Length = 340 Score = 70.1 bits (170), Expect = 4e-12 Identities = 32/101 (31%), Positives = 58/101 (57%) Frame = -2 Query: 424 DGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD 245 D + ++S D + LW+ TG+ T F GH D ++ S D +L +SG+ D++ K+WD Sbjct: 153 DDNNIVTSSGDTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDFKLFISGACDASAKLWD 212 Query: 244 IRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 +R +Q GH ++ A+ + P+GE + +G D + +L+ Sbjct: 213 VREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLF 253 Score = 62.0 bits (149), Expect = 1e-09 Identities = 38/140 (27%), Positives = 68/140 (48%), Gaps = 2/140 (1%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SG+ D + LW+ + TGH+ +N + F P+G+ + + S D S +L++ + Sbjct: 201 SGACDASAKLWDVR-EGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQ 259 Query: 355 FVTAFRGH--VADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 182 +TA+ + + +++S RLL +G D +WD + L GH + V + Sbjct: 260 ELTAYSDESIICGITSVAFSLSGRLLFAGYDDFNCNIWDSMKGERVGILSGHDNRVSCLG 319 Query: 181 WSPDGEKVVSGGKDRALKLW 122 + DG V +G D LK+W Sbjct: 320 VTADGMAVATGSWDSFLKVW 339 Score = 58.5 bits (140), Expect = 1e-08 Identities = 40/143 (27%), Positives = 68/143 (47%), Gaps = 5/143 (3%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 + S D T LW+ +Q K GH + SPD + S + D S KLW+ G Sbjct: 159 TSSGDTTCALWDIETGQQ-KTVFVGHTGDCMSLAVSPDFKLFISGACDASAKLWDVREGT 217 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADE-----VY 191 F GH +D+ I + + + +GS D++ +++D+RA Q+L ++DE + Sbjct: 218 CRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRA---DQELTAYSDESIICGIT 274 Query: 190 AVDWSPDGEKVVSGGKDRALKLW 122 +V +S G + +G D +W Sbjct: 275 SVAFSLSGRLLFAGYDDFNCNIW 297 Score = 53.9 bits (128), Expect = 3e-07 Identities = 25/73 (34%), Positives = 38/73 (52%) Frame = -2 Query: 340 RGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEK 161 RGH+A +Y + W+ DS+LL+S S+D L VWD +P + V ++P G Sbjct: 52 RGHLAKIYAMHWATDSKLLVSASQDGKLIVWDTYTTNKVHAIPLRSSWVMTCAYAPSGNF 111 Query: 160 VVSGGKDRALKLW 122 V GG D ++ Sbjct: 112 VACGGLDNMCSIY 124 Score = 39.3 bits (90), Expect = 0.007 Identities = 22/68 (32%), Positives = 35/68 (51%) Frame = -2 Query: 448 VNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSK 269 + V FS G+ L + D + +W+ + G+ V GH V + +AD + +GS Sbjct: 273 ITSVAFSLSGRLLFAGYDDFNCNIWDSMKGERVGILSGHDNRVSCLGVTADGMAVATGSW 332 Query: 268 DSTLKVWD 245 DS LKVW+ Sbjct: 333 DSFLKVWN 340 Score = 38.1 bits (87), Expect = 0.016 Identities = 35/169 (20%), Positives = 64/169 (37%), Gaps = 45/169 (26%) Frame = -2 Query: 493 ISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT---------------- 362 + + + + GH + ++++ D + L SAS D + +W+ T Sbjct: 43 VQMRTRRTLRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDTYTTNKVHAIPLRSSWVMT 102 Query: 361 ------GKFVT--------------AFRGHVADVYQISWSA---------DSRLLLSGSK 269 G FV + G+V ++S D +++ S Sbjct: 103 CAYAPSGNFVACGGLDNMCSIYSLKSREGNVKVSRELSAHTGYLSCCRFLDDNNIVTSSG 162 Query: 268 DSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 D+T +WDI + K GH + ++ SPD + +SG D + KLW Sbjct: 163 DTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDFKLFISGACDASAKLW 211 Score = 34.7 bits (78), Expect = 0.17 Identities = 16/55 (29%), Positives = 32/55 (58%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWN 371 +G DDF +W+ ++ + ++GH V+ + + DG +A+ S+D +K+WN Sbjct: 287 AGYDDFNCNIWD-SMKGERVGILSGHDNRVSCLGVTADGMAVATGSWDSFLKVWN 340
>GBB_ORYSA (Q40687) Guanine nucleotide-binding protein beta subunit| Length = 380 Score = 69.7 bits (169), Expect = 5e-12 Identities = 41/124 (33%), Positives = 74/124 (59%), Gaps = 8/124 (6%) Frame = -2 Query: 469 MTGHQKVVNHVYFSPDGQW-LASASFDKSVKLWNGITGKFVTAF-----RGHVADVYQIS 308 +TGH+ V+ + PD + L ++S D++ LW+ TG+ ++ F GH ADV +S Sbjct: 153 LTGHKGYVSSCQYVPDQETRLITSSGDQTCVLWDVTTGQRISIFGGEFPSGHTADVLSLS 212 Query: 307 W-SADSRLLLSGSKDSTLKVWDIR-ARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRA 134 S++S + +SGS D+T+++WDIR A + + GH ++ +V + PDG++ +G D Sbjct: 213 INSSNSNMFVSGSCDATVRLWDIRIASRAVRTYHGHEGDINSVKFFPDGQRFGTGSDDGT 272 Query: 133 LKLW 122 +L+ Sbjct: 273 CRLF 276 Score = 63.2 bits (152), Expect = 5e-10 Identities = 42/149 (28%), Positives = 69/149 (46%), Gaps = 11/149 (7%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SGS D T+ LW+ I+ + GH+ +N V F PDGQ + S D + +L++ TG Sbjct: 223 SGSCDATVRLWDIRIASRAVRTYHGHEGDINSVKFFPDGQRFGTGSDDGTCRLFDVRTGH 282 Query: 355 FVTAFR-------GHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDL----PG 209 + + + V I++S RLL +G + VWD ++ +L Sbjct: 283 QLQVYSREPDRNDNELPTVTSIAFSISGRLLFAGYSNGDCYVWDTLLAEVVLNLGNLQNS 342 Query: 208 HADEVYAVDWSPDGEKVVSGGKDRALKLW 122 H + + S DG + +G D+ LK+W Sbjct: 343 HEGRISCLGLSSDGSALCTGSWDKNLKIW 371 Score = 48.5 bits (114), Expect = 1e-05 Identities = 28/124 (22%), Positives = 60/124 (48%), Gaps = 8/124 (6%) Frame = -2 Query: 469 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 290 + GH V + ++P+ W+ SAS D + +WN +T + A + H V +++ + + Sbjct: 62 LQGHSGKVYSLDWTPEKNWIVSASQDGRLIVWNALTSQKTHAIKLHCPWVMTCAFAPNGQ 121 Query: 289 LLLSGSKDSTLKVWDIRAR-------KLKQDLPGHADEVYAVDWSPDGE-KVVSGGKDRA 134 + G DS ++++ ++ + + L GH V + + PD E ++++ D+ Sbjct: 122 SVACGGLDSACSIFNLNSQADRDGNIPVSRILTGHKGYVSSCQYVPDQETRLITSSGDQT 181 Query: 133 LKLW 122 LW Sbjct: 182 CVLW 185
>GBB3_HUMAN (P16520) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 3 (Transducin beta chain 3) Length = 340 Score = 69.3 bits (168), Expect = 6e-12 Identities = 32/101 (31%), Positives = 57/101 (56%) Frame = -2 Query: 424 DGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD 245 D + ++S D + LW+ TG+ T F GH D ++ S D L +SG+ D++ K+WD Sbjct: 153 DDNNIVTSSGDTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWD 212 Query: 244 IRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 +R +Q GH ++ A+ + P+GE + +G D + +L+ Sbjct: 213 VREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLF 253 Score = 60.1 bits (144), Expect = 4e-09 Identities = 38/140 (27%), Positives = 66/140 (47%), Gaps = 2/140 (1%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SG+ D + LW+ + TGH+ +N + F P+G+ + + S D S +L++ + Sbjct: 201 SGACDASAKLWDVR-EGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQ 259 Query: 355 FVTAFRGH--VADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 182 + F + + +++S RLL +G D VWD + L GH + V + Sbjct: 260 ELICFSHESIICGITSVAFSLSGRLLFAGYDDFNCNVWDSMKSERVGILSGHDNRVSCLG 319 Query: 181 WSPDGEKVVSGGKDRALKLW 122 + DG V +G D LK+W Sbjct: 320 VTADGMAVATGSWDSFLKIW 339 Score = 53.5 bits (127), Expect = 4e-07 Identities = 25/73 (34%), Positives = 38/73 (52%) Frame = -2 Query: 340 RGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEK 161 RGH+A +Y + W+ DS+LL+S S+D L VWD +P + V ++P G Sbjct: 52 RGHLAKIYAMHWATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSGNF 111 Query: 160 VVSGGKDRALKLW 122 V GG D ++ Sbjct: 112 VACGGLDNMCSIY 124 Score = 52.0 bits (123), Expect = 1e-06 Identities = 39/143 (27%), Positives = 65/143 (45%), Gaps = 5/143 (3%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 + S D T LW+ +Q K GH + SPD S + D S KLW+ G Sbjct: 159 TSSGDTTCALWDIETGQQ-KTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDVREGT 217 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADE-----VY 191 F GH +D+ I + + + +GS D++ +++D+RA Q+L + E + Sbjct: 218 CRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRA---DQELICFSHESIICGIT 274 Query: 190 AVDWSPDGEKVVSGGKDRALKLW 122 +V +S G + +G D +W Sbjct: 275 SVAFSLSGRLLFAGYDDFNCNVW 297 Score = 38.9 bits (89), Expect = 0.009 Identities = 26/128 (20%), Positives = 56/128 (43%), Gaps = 4/128 (3%) Frame = -2 Query: 493 ISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQ 314 + + + + GH + ++++ D + L SAS D + +W+ T V A + V Sbjct: 43 VQMRTRRTLRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMT 102 Query: 313 ISWSADSRLLLSGSKDSTLKVWDIRAR----KLKQDLPGHADEVYAVDWSPDGEKVVSGG 146 +++ + G D+ ++++++R K+ ++L H + + D V S G Sbjct: 103 CAYAPSGNFVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDNNIVTSSG 162 Query: 145 KDRALKLW 122 D LW Sbjct: 163 -DTTCALW 169 Score = 37.7 bits (86), Expect = 0.020 Identities = 26/100 (26%), Positives = 48/100 (48%), Gaps = 3/100 (3%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVV---NHVYFSPDGQWLASASFDKSVKLWNGI 365 +GSDD + L++ + + H+ ++ V FS G+ L + D + +W+ + Sbjct: 243 TGSDDASCRLFD--LRADQELICFSHESIICGITSVAFSLSGRLLFAGYDDFNCNVWDSM 300 Query: 364 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD 245 + V GH V + +AD + +GS DS LK+W+ Sbjct: 301 KSERVGILSGHDNRVSCLGVTADGMAVATGSWDSFLKIWN 340
>CORO_YEAST (Q06440) Coronin-like protein| Length = 651 Score = 69.3 bits (168), Expect = 6e-12 Identities = 49/159 (30%), Positives = 78/159 (49%), Gaps = 21/159 (13%) Frame = -2 Query: 535 SGSDDFTMFLWE---------------PTISKQPKARMTGHQKVVNHVYFSPDGQ-WLAS 404 SGSDD + +W+ I +P +TGH + V HV + P + LAS Sbjct: 99 SGSDDSKIGIWDIPENYKFHDHVDEDGEPIDIKPVKFLTGHARKVGHVLYHPVAENVLAS 158 Query: 403 ASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLK 224 +S D +VKLWN TGK + + H V +S+S D L + ++D L+VW+IR K+ Sbjct: 159 SSGDYTVKLWNVETGKDMITLK-HPDMVTSMSFSYDGNYLATVARDKKLRVWNIREEKIV 217 Query: 223 QDLPGHAD-EVYAVDWSPDGEKVVSGG----KDRALKLW 122 + P H + V W + +++ + G DR + +W Sbjct: 218 SEGPAHTGAKNQRVVWLGNSDRLATTGFSKLSDRQIGIW 256 Score = 37.4 bits (85), Expect = 0.027 Identities = 30/95 (31%), Positives = 39/95 (41%), Gaps = 18/95 (18%) Frame = -2 Query: 352 VTAFRGHVADVYQISWSA-DSRLLLSGSKDSTLKVWDIRARKLKQD-------------- 218 V FRGH A V + + + SGS DS + +WDI D Sbjct: 74 VPLFRGHTAQVLDTDFDPFNDHRIASGSDDSKIGIWDIPENYKFHDHVDEDGEPIDIKPV 133 Query: 217 --LPGHADEVYAVDWSPDGEKVV-SGGKDRALKLW 122 L GHA +V V + P E V+ S D +KLW Sbjct: 134 KFLTGHARKVGHVLYHPVAENVLASSSGDYTVKLW 168
>YAGE_SCHPO (Q9UTN4) Hypothetical WD-repeat protein C12G12.14c in chromosome I| Length = 509 Score = 68.9 bits (167), Expect = 8e-12 Identities = 46/135 (34%), Positives = 70/135 (51%), Gaps = 3/135 (2%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 + SDD ++ +W +S + + ++TGH V V + P LAS S D VK W+ TG Sbjct: 181 TASDDGSLKVWNFHMSTE-ELKLTGHGWDVKTVDWHPSKGLLASGSKDNLVKFWDPRTGT 239 Query: 355 FVTAFRGHVADVYQISWSAD--SRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 182 + GH + Q S+ + S L + S+DST +V+D+RA K + L GH +V V Sbjct: 240 CIATLHGHKNTIMQASFQKNFGSNYLATVSRDSTCRVFDLRAMKDVRVLRGHEKDVNCVT 299 Query: 181 WSP-DGEKVVSGGKD 140 W P + +GG D Sbjct: 300 WHPLYPNLLTTGGSD 314 Score = 63.5 bits (153), Expect = 3e-10 Identities = 43/151 (28%), Positives = 57/151 (37%), Gaps = 41/151 (27%) Frame = -2 Query: 451 VVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSG- 275 V+N V ++PDG+ L + S LWNG+T F + H V WS D R L+SG Sbjct: 83 VINVVRWTPDGRRLLTGSSTGEFTLWNGLTFNFELINQSHDYAVRCAEWSTDGRWLISGD 142 Query: 274 ----------------------------------------SKDSTLKVWDIRARKLKQDL 215 S D +LKVW+ + L Sbjct: 143 GGGMVKYFEPNLNNVKIVQAHEMEVRDVAFSPNDSKFVTASDDGSLKVWNFHMSTEELKL 202 Query: 214 PGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 GH +V VDW P + SG KD +K W Sbjct: 203 TGHGWDVKTVDWHPSKGLLASGSKDNLVKFW 233 Score = 57.8 bits (138), Expect = 2e-08 Identities = 32/89 (35%), Positives = 42/89 (47%) Frame = -2 Query: 460 HQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLL 281 H+ V V FSP+ +AS D S+K+WN GH DV + W LL Sbjct: 163 HEMEVRDVAFSPNDSKFVTASDDGSLKVWNFHMSTEELKLTGHGWDVKTVDWHPSKGLLA 222 Query: 280 SGSKDSTLKVWDIRARKLKQDLPGHADEV 194 SGSKD+ +K WD R L GH + + Sbjct: 223 SGSKDNLVKFWDPRTGTCIATLHGHKNTI 251
>HIRA_MOUSE (Q61666) HIRA protein (TUP1-like enhancer of split protein 1)| Length = 1015 Score = 68.6 bits (166), Expect = 1e-11 Identities = 42/137 (30%), Positives = 65/137 (47%), Gaps = 20/137 (14%) Frame = -2 Query: 472 RMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWN-----------GITGKF--------V 350 +M H VN V +S G +LAS DK + +W G +GK V Sbjct: 65 QMDNHLACVNCVRWSNSGMYLASGGDDKLIMVWKRATYIGPSTVFGSSGKLANVEQWRCV 124 Query: 349 TAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD-IRARKLKQDLPGHADEVYAVDWSP 173 + R H DV ++WS L S S D+T+ +W+ ++ ++ L GH+ V + W P Sbjct: 125 SILRSHSGDVMDVAWSPHDAWLASCSVDNTVVIWNAVKFPEILATLRGHSGLVKGLTWDP 184 Query: 172 DGEKVVSGGKDRALKLW 122 G+ + S DR+LK+W Sbjct: 185 VGKYIASQADDRSLKVW 201 Score = 55.5 bits (132), Expect = 9e-08 Identities = 41/166 (24%), Positives = 70/166 (42%), Gaps = 27/166 (16%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 S S D T+ +W + A + GH +V + + P G+++AS + D+S+K+W + + Sbjct: 148 SCSVDNTVVIWNAVKFPEILATLRGHSGLVKGLTWDPVGKYIASQADDRSLKVWRTLDWQ 207 Query: 355 FVTAFR------GHVADVYQISWSADSRLLLS----GSKDSTLKVWDIRARKLKQDLPGH 206 T+ G V ++SWS D L+S + T ++ + K D GH Sbjct: 208 LETSITKPCDECGGTTHVLRLSWSPDGHYLVSAHAMNNSGPTAQIIEREGWKTNMDFVGH 267 Query: 205 ADEVYAVDWSPDGEK-----------------VVSGGKDRALKLWM 119 V V ++P K G KDR+L +W+ Sbjct: 268 RKAVTVVKFNPKIFKKKQKNGSSTKPSCPYCCCAVGSKDRSLSVWL 313
>HIRA_HUMAN (P54198) HIRA protein (TUP1-like enhancer of split protein 1)| Length = 1017 Score = 68.6 bits (166), Expect = 1e-11 Identities = 42/137 (30%), Positives = 65/137 (47%), Gaps = 20/137 (14%) Frame = -2 Query: 472 RMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWN-----------GITGKF--------V 350 +M H VN V +S G +LAS DK + +W G +GK V Sbjct: 65 QMDNHLACVNCVRWSNSGMYLASGGDDKLIMVWKRATYIGPSTVFGSSGKLANVEQWRCV 124 Query: 349 TAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD-IRARKLKQDLPGHADEVYAVDWSP 173 + R H DV ++WS L S S D+T+ +W+ ++ ++ L GH+ V + W P Sbjct: 125 SILRNHSGDVMDVAWSPHDAWLASCSVDNTVVIWNAVKFPEILATLRGHSGLVKGLTWDP 184 Query: 172 DGEKVVSGGKDRALKLW 122 G+ + S DR+LK+W Sbjct: 185 VGKYIASQADDRSLKVW 201 Score = 55.5 bits (132), Expect = 9e-08 Identities = 41/166 (24%), Positives = 70/166 (42%), Gaps = 27/166 (16%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 S S D T+ +W + A + GH +V + + P G+++AS + D+S+K+W + + Sbjct: 148 SCSVDNTVVIWNAVKFPEILATLRGHSGLVKGLTWDPVGKYIASQADDRSLKVWRTLDWQ 207 Query: 355 FVTAFR------GHVADVYQISWSADSRLLLS----GSKDSTLKVWDIRARKLKQDLPGH 206 T+ G V ++SWS D L+S + T ++ + K D GH Sbjct: 208 LETSITKPFDECGGTTHVLRLSWSPDGHYLVSAHAMNNSGPTAQIIEREGWKTNMDFVGH 267 Query: 205 ADEVYAVDWSPDGEK-----------------VVSGGKDRALKLWM 119 V V ++P K G KDR+L +W+ Sbjct: 268 RKAVTVVKFNPKIFKKKQKNGSSAKPSCPYCCCAVGSKDRSLSVWL 313
>WSB1_HUMAN (Q9Y6I7) WD repeat and SOCS box-containing protein 1 (WSB-1) (SOCS| box-containing WD protein SWiP-1) Length = 421 Score = 68.6 bits (166), Expect = 1e-11 Identities = 38/118 (32%), Positives = 63/118 (53%), Gaps = 2/118 (1%) Frame = -2 Query: 469 MTGHQKVVNHVYFSPDGQW-LASASFDKSVKLWN-GITGKFVTAFRGHVADVYQISWSAD 296 + H +VV + F+PDG L SAS DK++++W+ G + RGH VY ++S D Sbjct: 166 LVDHTEVVRDLTFAPDGSLILVSASRDKTLRVWDLKDDGNMMKVLRGHQNWVYSCAFSPD 225 Query: 295 SRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 S +L S + +W++ + + L GH +V A D+SPDG + + D + +W Sbjct: 226 SSMLCSVGASKAVFLWNMDKYTMIRKLEGHHHDVVACDFSPDGALLATASYDTRVYIW 283 Score = 61.2 bits (147), Expect = 2e-09 Identities = 35/106 (33%), Positives = 58/106 (54%), Gaps = 2/106 (1%) Frame = -2 Query: 433 FSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLL-SGSKDSTL 257 F D LA+ + +K+W+ TGK + H V ++++ D L+L S S+D TL Sbjct: 136 FGQDQLLLATGLNNGRIKIWDVYTGKLLLNLVDHTEVVRDLTFAPDGSLILVSASRDKTL 195 Query: 256 KVWDIR-ARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 +VWD++ + + L GH + VY+ +SPD + S G +A+ LW Sbjct: 196 RVWDLKDDGNMMKVLRGHQNWVYSCAFSPDSSMLCSVGASKAVFLW 241 Score = 59.7 bits (143), Expect = 5e-09 Identities = 43/151 (28%), Positives = 63/151 (41%), Gaps = 13/151 (8%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 S S D T+ +W+ + GHQ V FSPD L S K+V LWN Sbjct: 188 SASRDKTLRVWDLKDDGNMMKVLRGHQNWVYSCAFSPDSSMLCSVGASKAVFLWNMDKYT 247 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQD-----------LPG 209 + GH DV +S D LL + S D+ + +WD + + G Sbjct: 248 MIRKLEGHHHDVVACDFSPDGALLATASYDTRVYIWDPHNGDILMEFGHLFPPPTPIFAG 307 Query: 208 HADE--VYAVDWSPDGEKVVSGGKDRALKLW 122 A++ V +V +S DG V S D+ ++ W Sbjct: 308 GANDRWVRSVSFSHDGLHVASLADDKMVRFW 338 Score = 45.1 bits (105), Expect = 1e-04 Identities = 20/67 (29%), Positives = 38/67 (56%), Gaps = 1/67 (1%) Frame = -2 Query: 319 YQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKV-VSGGK 143 ++ + D LL +G + +K+WD+ KL +L H + V + ++PDG + VS + Sbjct: 132 HRFRFGQDQLLLATGLNNGRIKIWDVYTGKLLLNLVDHTEVVRDLTFAPDGSLILVSASR 191 Query: 142 DRALKLW 122 D+ L++W Sbjct: 192 DKTLRVW 198
>COPB2_MOUSE (O55029) Coatomer subunit beta' (Beta'-coat protein) (Beta'-COP)| (p102) Length = 905 Score = 68.2 bits (165), Expect = 1e-11 Identities = 39/141 (27%), Positives = 65/141 (46%), Gaps = 3/141 (2%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSP-DGQWLASASFDKSVKLWNGITG 359 + SDD + LW+ GH V + +P D ASAS D+++K+W + Sbjct: 116 TSSDDMLIKLWDWDKKWSCSQVFEGHTHYVMQIVINPKDNNQFASASLDRTIKVWQLGSS 175 Query: 358 KFVTAFRGHVADVYQISW--SADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAV 185 GH V I + D L+SG+ D +K+WD + + Q L GHA V Sbjct: 176 SPNFTLEGHEKGVNCIDYYSGGDKPYLISGADDRLVKIWDYQNKTCVQTLEGHAQNVSCA 235 Query: 184 DWSPDGEKVVSGGKDRALKLW 122 + P+ +++G +D +++W Sbjct: 236 SFHPELPIIITGSEDGTVRIW 256 Score = 55.5 bits (132), Expect = 9e-08 Identities = 34/119 (28%), Positives = 60/119 (50%), Gaps = 2/119 (1%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHV--YFSPDGQWLASASFDKSVKLWNGIT 362 S S D T+ +W+ S P + GH+K VN + Y D +L S + D+ VK+W+ Sbjct: 160 SASLDRTIKVWQLG-SSSPNFTLEGHEKGVNCIDYYSGGDKPYLISGADDRLVKIWDYQN 218 Query: 361 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAV 185 V GH +V S+ + ++++GS+D T+++W +L+ L + V+ V Sbjct: 219 KTCVQTLEGHAQNVSCASFHPELPIIITGSEDGTVRIWHSSTYRLESTLNYGMERVWCV 277 Score = 43.1 bits (100), Expect = 5e-04 Identities = 25/119 (21%), Positives = 50/119 (42%) Frame = -2 Query: 478 KARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSA 299 K ++T V V P W+ ++ ++ SV +WN T V F V + A Sbjct: 8 KRKLTARSDRVKSVDLHPTEPWMLASLYNGSVCVWNHETQTLVKTFEVCDLPVRAAKFVA 67 Query: 298 DSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 +++G+ D ++V++ + H+D + + P +++ D +KLW Sbjct: 68 RKNWVVTGADDMQIRVFNYNTLERVHMFEAHSDYIRCIAVHPTQPFILTSSDDMLIKLW 126
>COPB2_HUMAN (P35606) Coatomer subunit beta' (Beta'-coat protein) (Beta'-COP)| (p102) Length = 905 Score = 68.2 bits (165), Expect = 1e-11 Identities = 39/141 (27%), Positives = 65/141 (46%), Gaps = 3/141 (2%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSP-DGQWLASASFDKSVKLWNGITG 359 + SDD + LW+ GH V + +P D ASAS D+++K+W + Sbjct: 115 TSSDDMLIKLWDWDKKWSCSQVFEGHTHYVMQIVINPKDNNQFASASLDRTIKVWQLGSS 174 Query: 358 KFVTAFRGHVADVYQISW--SADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAV 185 GH V I + D L+SG+ D +K+WD + + Q L GHA V Sbjct: 175 SPNFTLEGHEKGVNCIDYYSGGDKPYLISGADDRLVKIWDYQNKTCVQTLEGHAQNVSCA 234 Query: 184 DWSPDGEKVVSGGKDRALKLW 122 + P+ +++G +D +++W Sbjct: 235 SFHPELPIIITGSEDGTVRIW 255 Score = 55.5 bits (132), Expect = 9e-08 Identities = 34/119 (28%), Positives = 60/119 (50%), Gaps = 2/119 (1%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHV--YFSPDGQWLASASFDKSVKLWNGIT 362 S S D T+ +W+ S P + GH+K VN + Y D +L S + D+ VK+W+ Sbjct: 159 SASLDRTIKVWQLG-SSSPNFTLEGHEKGVNCIDYYSGGDKPYLISGADDRLVKIWDYQN 217 Query: 361 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAV 185 V GH +V S+ + ++++GS+D T+++W +L+ L + V+ V Sbjct: 218 KTCVQTLEGHAQNVSCASFHPELPIIITGSEDGTVRIWHSSTYRLESTLNYGMERVWCV 276 Score = 43.1 bits (100), Expect = 5e-04 Identities = 25/119 (21%), Positives = 50/119 (42%) Frame = -2 Query: 478 KARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSA 299 K ++T V V P W+ ++ ++ SV +WN T V F V + A Sbjct: 7 KRKLTARSDRVKSVDLHPTEPWMLASLYNGSVCVWNHETQTLVKTFEVCDLPVRAAKFVA 66 Query: 298 DSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 +++G+ D ++V++ + H+D + + P +++ D +KLW Sbjct: 67 RKNWVVTGADDMQIRVFNYNTLERVHMFEAHSDYIRCIAVHPTQPFILTSSDDMLIKLW 125
>COPB2_BOVIN (P35605) Coatomer subunit beta' (Beta'-coat protein) (Beta'-COP)| (p102) Length = 905 Score = 68.2 bits (165), Expect = 1e-11 Identities = 39/141 (27%), Positives = 65/141 (46%), Gaps = 3/141 (2%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSP-DGQWLASASFDKSVKLWNGITG 359 + SDD + LW+ GH V + +P D ASAS D+++K+W + Sbjct: 115 TSSDDMLIKLWDWDKKWSCSQVFEGHTHYVMQIVINPKDNNQFASASLDRTIKVWQLGSS 174 Query: 358 KFVTAFRGHVADVYQISW--SADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAV 185 GH V I + D L+SG+ D +K+WD + + Q L GHA V Sbjct: 175 SPNFTLEGHEKGVNCIDYYSGGDKPYLISGADDRLVKIWDYQNKTCVQTLEGHAQNVSCA 234 Query: 184 DWSPDGEKVVSGGKDRALKLW 122 + P+ +++G +D +++W Sbjct: 235 SFHPELPIIITGSEDGTVRIW 255 Score = 55.5 bits (132), Expect = 9e-08 Identities = 34/119 (28%), Positives = 60/119 (50%), Gaps = 2/119 (1%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHV--YFSPDGQWLASASFDKSVKLWNGIT 362 S S D T+ +W+ S P + GH+K VN + Y D +L S + D+ VK+W+ Sbjct: 159 SASLDRTIKVWQLG-SSSPNFTLEGHEKGVNCIDYYSGGDKPYLISGADDRLVKIWDYQN 217 Query: 361 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAV 185 V GH +V S+ + ++++GS+D T+++W +L+ L + V+ V Sbjct: 218 KTCVQTLEGHAQNVSCASFHPELPIIITGSEDGTVRIWHSSTYRLESTLNYGMERVWCV 276 Score = 43.1 bits (100), Expect = 5e-04 Identities = 25/119 (21%), Positives = 50/119 (42%) Frame = -2 Query: 478 KARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSA 299 K ++T V V P W+ ++ ++ SV +WN T V F V + A Sbjct: 7 KRKLTARSDRVKSVDLHPTEPWMLASLYNGSVCVWNHETQTLVKTFEVCDLPVRAAKFVA 66 Query: 298 DSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 +++G+ D ++V++ + H+D + + P +++ D +KLW Sbjct: 67 RKNWVVTGADDMQIRVFNYNTLERVHMFEAHSDYIRCIAVHPTQPFILTSSDDMLIKLW 125
>RBBP7_PONPY (Q5R654) Histone-binding protein RBBP7 (Retinoblastoma-binding| protein 7) (RBBP-7) Length = 426 Score = 67.8 bits (164), Expect = 2e-11 Identities = 53/152 (34%), Positives = 76/152 (50%), Gaps = 14/152 (9%) Frame = -2 Query: 535 SGSDDFTMFLWE----PTISK--QPKARMTGHQKVVNHVYFSPDGQWL-ASASFDKSVKL 377 S SDD T+ LW+ P K KA TGH VV V + + L S + D+ + + Sbjct: 194 SASDDHTVCLWDINAGPKEGKIVDAKAVFTGHSAVVEDVAWHLLHESLFGSVADDQKLMM 253 Query: 376 WN---GITGKFVTAFRGHVADVYQISWSADSRLLLS-GSKDSTLKVWDIRARKLK-QDLP 212 W+ T K H A+V +S++ S +L+ GS D T+ +WD+R KLK Sbjct: 254 WDTRSNTTSKPSHLVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHTFE 313 Query: 211 GHADEVY-AVDWSPDGEKVV-SGGKDRALKLW 122 H DE++ V WSP E ++ S G DR L +W Sbjct: 314 SHKDEIFQVVHWSPHNETILASSGTDRRLNVW 345 Score = 36.6 bits (83), Expect = 0.045 Identities = 28/82 (34%), Positives = 39/82 (47%), Gaps = 9/82 (10%) Frame = -2 Query: 340 RGHVADVYQISWSAD-SRLLLSGSKDSTLKVWDIRAR-------KLKQDLPGHADEVYAV 185 RGH + Y +SW+++ S LLS S D T+ +WDI A K GH+ V V Sbjct: 173 RGHQKEGYGLSWNSNLSGHLLSASDDHTVCLWDINAGPKEGKIVDAKAVFTGHSAVVEDV 232 Query: 184 DWSPDGEKVV-SGGKDRALKLW 122 W E + S D+ L +W Sbjct: 233 AWHLLHESLFGSVADDQKLMMW 254
>FZR_MOUSE (Q9R1K5) Fizzy-related protein homolog (Fzr) (Cdh1/Hct1 homolog)| Length = 493 Score = 67.8 bits (164), Expect = 2e-11 Identities = 42/134 (31%), Positives = 67/134 (50%), Gaps = 3/134 (2%) Frame = -2 Query: 514 MFLWEPTISKQPK-ARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFR 338 ++LW S+ + ++ V V +S G +A + V++W+ GK ++ Sbjct: 209 VYLWSACTSQVTRLCDLSVEGDSVTSVGWSERGNLVAVGTHKGFVQIWDAAAGKKLSMLE 268 Query: 337 GHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQD--LPGHADEVYAVDWSPDGE 164 GH A V ++W+AD L SGS+D + DIR L+ + L GH EV + WS D + Sbjct: 269 GHTARVGALAWNADQ--LSSGSRDRMILQRDIRTPPLQSERRLQGHRQEVCGLKWSTDHQ 326 Query: 163 KVVSGGKDRALKLW 122 + SGG D L +W Sbjct: 327 LLASGGNDNKLLVW 340 Score = 59.7 bits (143), Expect = 5e-09 Identities = 39/143 (27%), Positives = 68/143 (47%), Gaps = 5/143 (3%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASA---SFDKSVKLWNGI 365 SG +D + +W + S P + T H V + +SP L ++ + D+ ++ WN + Sbjct: 330 SGGNDNKLLVWNHS-SLSPVQQYTEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTL 388 Query: 364 TGKFVTAFRGHVADVYQISWSADSRLLLS--GSKDSTLKVWDIRARKLKQDLPGHADEVY 191 TG+ + + V ++WS + L+S G + + VW + L GH+ V Sbjct: 389 TGQPLQCIDTG-SQVCNLAWSKHANELVSTHGYSQNQILVWKYPSLTQVAKLTGHSYRVL 447 Query: 190 AVDWSPDGEKVVSGGKDRALKLW 122 + SPDGE +V+G D L+ W Sbjct: 448 YLAMSPDGEAIVTGAGDETLRFW 470 Score = 50.4 bits (119), Expect = 3e-06 Identities = 37/134 (27%), Positives = 62/134 (46%), Gaps = 5/134 (3%) Frame = -2 Query: 508 LWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFR--G 335 +W+ K+ + + GH V + ++ D L+S S D+ + + T + R G Sbjct: 255 IWDAAAGKK-LSMLEGHTARVGALAWNADQ--LSSGSRDRMILQRDIRTPPLQSERRLQG 311 Query: 334 HVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVV 155 H +V + WS D +LL SG D+ L VW+ + Q H V A+ WSP ++ Sbjct: 312 HRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQYTEHLAAVKAIAWSPHQHGLL 371 Query: 154 SGG---KDRALKLW 122 + G DR ++ W Sbjct: 372 ASGGGTADRCIRFW 385 Score = 39.7 bits (91), Expect = 0.005 Identities = 26/94 (27%), Positives = 40/94 (42%), Gaps = 2/94 (2%) Frame = -2 Query: 406 SASFDKSVKLWNGITGKFVTAFRGHVA--DVYQISWSADSRLLLSGSKDSTLKVWDIRAR 233 S V LW+ T + V V + WS L+ G+ +++WD A Sbjct: 202 SVGLGTCVYLWSACTSQVTRLCDLSVEGDSVTSVGWSERGNLVAVGTHKGFVQIWDAAAG 261 Query: 232 KLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRAL 131 K L GH V A+ W+ D ++ SG +DR + Sbjct: 262 KKLSMLEGHTARVGALAWNAD--QLSSGSRDRMI 293 Score = 33.5 bits (75), Expect = 0.38 Identities = 12/35 (34%), Positives = 24/35 (68%) Frame = -2 Query: 475 ARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWN 371 A++TGH V ++ SPDG+ + + + D++++ WN Sbjct: 437 AKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWN 471
>COPA_YEAST (P53622) Coatomer subunit alpha (Alpha-coat protein) (Alpha-COP)| Length = 1201 Score = 67.4 bits (163), Expect = 2e-11 Identities = 44/168 (26%), Positives = 69/168 (41%), Gaps = 30/168 (17%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 S DD+T+ +W +K +TGH V V+F + W+ SAS D+++++WN K Sbjct: 70 SAGDDYTIKVWSLDTNKCLYT-LTGHLDYVRTVFFHRELPWIISASDDQTIRIWNWQNRK 128 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLP------------ 212 + GH V + L++S S D T+++WDI + + P Sbjct: 129 EIACLTGHNHFVMCAQFHPTDDLIVSASLDETIRIWDISGLRKRHSAPGTSSFEEQMSAQ 188 Query: 211 ------------------GHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 GH V + P +VSG DR +KLW Sbjct: 189 QNLLDGSLGDCVVKFILEGHTRGVNWASFHPTLPLIVSGSDDRQVKLW 236 Score = 60.1 bits (144), Expect = 4e-09 Identities = 46/170 (27%), Positives = 73/170 (42%), Gaps = 32/170 (18%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWN----- 371 S SDD T+ +W K+ A +TGH V F P + SAS D+++++W+ Sbjct: 112 SASDDQTIRIWNWQNRKEI-ACLTGHNHFVMCAQFHPTDDLIVSASLDETIRIWDISGLR 170 Query: 370 -----------------------GITGKFVTAF--RGHVADVYQISWSADSRLLLSGSKD 266 G G V F GH V S+ L++SGS D Sbjct: 171 KRHSAPGTSSFEEQMSAQQNLLDGSLGDCVVKFILEGHTRGVNWASFHPTLPLIVSGSDD 230 Query: 265 STLKVWDIRARKLKQ--DLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 +K+W + A K + GH + V +V + P ++S G+D+ L++W Sbjct: 231 RQVKLWRMSATKAWEVDTCRGHTNNVDSVIFHPHQNLIISVGEDKTLRVW 280 Score = 58.2 bits (139), Expect = 1e-08 Identities = 31/117 (26%), Positives = 55/117 (47%) Frame = -2 Query: 472 RMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADS 293 R H+ V + F P SA D ++K+W+ T K + GH+ V + + + Sbjct: 48 RFEDHEGPVRGLDFHPTQPIFVSAGDDYTIKVWSLDTNKCLYTLTGHLDYVRTVFFHREL 107 Query: 292 RLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 ++S S D T+++W+ + RK L GH V + P + +VS D +++W Sbjct: 108 PWIISASDDQTIRIWNWQNRKEIACLTGHNHFVMCAQFHPTDDLIVSASLDETIRIW 164 Score = 57.4 bits (137), Expect = 2e-08 Identities = 27/106 (25%), Positives = 48/106 (45%) Frame = -2 Query: 439 VYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDST 260 + F P W+ A F +++LW+ G + F H V + + + +S D T Sbjct: 17 IAFHPSRPWVLVALFSSTIQLWDYRMGTLLHRFEDHEGPVRGLDFHPTQPIFVSAGDDYT 76 Query: 259 LKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 +KVW + K L GH D V V + + ++S D+ +++W Sbjct: 77 IKVWSLDTNKCLYTLTGHLDYVRTVFFHRELPWIISASDDQTIRIW 122 Score = 49.3 bits (116), Expect = 7e-06 Identities = 28/81 (34%), Positives = 40/81 (49%), Gaps = 2/81 (2%) Frame = -2 Query: 469 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKF--VTAFRGHVADVYQISWSAD 296 + GH + VN F P + S S D+ VKLW K V RGH +V + + Sbjct: 205 LEGHTRGVNWASFHPTLPLIVSGSDDRQVKLWRMSATKAWEVDTCRGHTNNVDSVIFHPH 264 Query: 295 SRLLLSGSKDSTLKVWDIRAR 233 L++S +D TL+VWD+ R Sbjct: 265 QNLIISVGEDKTLRVWDLDKR 285
>PRP17_YEAST (P40968) Pre-mRNA-splicing factor PRP17 (Cell division control| protein 40) Length = 455 Score = 67.4 bits (163), Expect = 2e-11 Identities = 40/143 (27%), Positives = 68/143 (47%), Gaps = 3/143 (2%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SG +D T+ +W+ + GH K + + F+ D Q S+SFD+SVK+W+ TGK Sbjct: 180 SGGNDHTIKIWDFYHDYECLRDFQGHNKPIKALRFTEDCQSFLSSSFDRSVKIWDTETGK 239 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARK---LKQDLPGHADEVYAV 185 T + S + + G +S + +D R + L Q H + A+ Sbjct: 240 VKTRLHLNSTPADVESRPTNPHEFIVGLSNSKILHYDDRVSENQGLVQTYDHHLSSILAL 299 Query: 184 DWSPDGEKVVSGGKDRALKLWMN 116 + PDG K +S +D+ +++W N Sbjct: 300 KYFPDGSKFISSSEDKTVRIWEN 322 Score = 42.7 bits (99), Expect = 6e-04 Identities = 38/139 (27%), Positives = 62/139 (44%), Gaps = 9/139 (6%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 S S+D T+ +WE I+ K Q + + P + + S D + ++ + K Sbjct: 310 SSSEDKTVRIWENQINVPIKQISDTAQHSMPFLNVHPSQNYFCAQSMDNRIYSFS-LKPK 368 Query: 355 F----VTAFRGHVADVYQIS--WSADSRLLLSGSKDSTLKVWDIRARKLKQD--LPGHAD 200 + F+GH + Y IS +S D R + SG S L WD +L + +PG+ Sbjct: 369 YKRHPKKIFKGHSSAGYGISLAFSGDGRYICSGDSKSRLFTWDWNTSRLLNNIKIPGN-K 427 Query: 199 EVYAVDWSP-DGEKVVSGG 146 + VDW P + KV+ G Sbjct: 428 PITQVDWHPQETSKVICSG 446 Score = 42.0 bits (97), Expect = 0.001 Identities = 19/57 (33%), Positives = 33/57 (57%), Gaps = 1/57 (1%) Frame = -2 Query: 289 LLLSGSKDSTLKVWDI-RARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 L+LSG D T+K+WD + +D GH + A+ ++ D + +S DR++K+W Sbjct: 177 LILSGGNDHTIKIWDFYHDYECLRDFQGHNKPIKALRFTEDCQSFLSSSFDRSVKIW 233 Score = 32.0 bits (71), Expect = 1.1 Identities = 13/39 (33%), Positives = 24/39 (61%), Gaps = 1/39 (2%) Frame = -2 Query: 235 RKLKQDLPGHADEVYAVDWSPD-GEKVVSGGKDRALKLW 122 +K+ ++ PGH + A+ + P G ++SGG D +K+W Sbjct: 152 KKVIRNYPGHPEGTTALKFLPKTGHLILSGGNDHTIKIW 190
>WDR1_CAEEL (Q11176) Actin-interacting protein 1 (AIP1) (Uncoordinated protein| 78) Length = 611 Score = 67.4 bits (163), Expect = 2e-11 Identities = 37/115 (32%), Positives = 60/115 (52%), Gaps = 7/115 (6%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SGSDD T+ ++E K K+ H K V+ V ++PDG AS D ++ L+NG+ G Sbjct: 165 SGSDDNTVAIFEGPPFKF-KSTFGEHTKFVHSVRYNPDGSLFASTGGDGTIVLYNGVDGT 223 Query: 355 FVTAFR-------GHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLP 212 F H V+ ++WS D + S S D T+K+W++ K+++ +P Sbjct: 224 KTGVFEDDSLKNVAHSGSVFGLTWSPDGTKIASASADKTIKIWNVATLKVEKTIP 278 Score = 60.5 bits (145), Expect = 3e-09 Identities = 34/124 (27%), Positives = 60/124 (48%), Gaps = 8/124 (6%) Frame = -2 Query: 469 MTGHQKVVNHVYFSPDGQW-LASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADS 293 +TG + +N V F P + + S S D +V ++ G KF + F H V+ + ++ D Sbjct: 143 LTGQARAMNSVDFKPSRPFRIISGSDDNTVAIFEGPPFKFKSTFGEHTKFVHSVRYNPDG 202 Query: 292 RLLLSGSKDSTLKVWD----IRARKLKQDL---PGHADEVYAVDWSPDGEKVVSGGKDRA 134 L S D T+ +++ + + D H+ V+ + WSPDG K+ S D+ Sbjct: 203 SLFASTGGDGTIVLYNGVDGTKTGVFEDDSLKNVAHSGSVFGLTWSPDGTKIASASADKT 262 Query: 133 LKLW 122 +K+W Sbjct: 263 IKIW 266 Score = 42.7 bits (99), Expect = 6e-04 Identities = 36/146 (24%), Positives = 65/146 (44%), Gaps = 9/146 (6%) Frame = -2 Query: 532 GSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSV---KLWNGIT 362 G D + +++ + + + + H + V FS +G +L + + V + N Sbjct: 466 GGQDSKVHVYKLSGASVSEVKTIVHPAEITSVAFSNNGAFLVATDQSRKVIPYSVANNFE 525 Query: 361 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLP-----GHA-D 200 ++ H A V +SWS D+ L +GS D+++ VW++ D P HA Sbjct: 526 LAHTNSWTFHTAKVACVSWSPDNVRLATGSLDNSVIVWNMNK---PSDHPIIIKGAHAMS 582 Query: 199 EVYAVDWSPDGEKVVSGGKDRALKLW 122 V +V W + +VS G+D +K W Sbjct: 583 SVNSVIWLNE-TTIVSAGQDSNIKFW 607 Score = 34.3 bits (77), Expect = 0.23 Identities = 36/160 (22%), Positives = 53/160 (33%), Gaps = 55/160 (34%) Frame = -2 Query: 460 HQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT--------------------------- 362 H V + +SPDG +ASAS DK++K+WN T Sbjct: 238 HSGSVFGLTWSPDGTKIASASADKTIKIWNVATLKVEKTIPVGTRIEDQQLGIIWTKQAL 297 Query: 361 ----------------GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARK 230 G GH + +S SAD + L S + + WDI Sbjct: 298 VSISANGFINFVNPELGSIDQVRYGHNKAITALSSSADGKTLFSADAEGHINSWDISTGI 357 Query: 229 LKQDLPG-HA-----------DEVYAVDWSPDGEKVVSGG 146 + P HA +++ V W + V +GG Sbjct: 358 SNRVFPDVHATMITGIKTTSKGDLFTVSWDDHLKVVPAGG 397 Score = 34.3 bits (77), Expect = 0.23 Identities = 35/165 (21%), Positives = 57/165 (34%), Gaps = 50/165 (30%) Frame = -2 Query: 466 TGHQKVVNHVYFSPDGQWLASASFDKSVKLWN-----GITGKFVTAFRGHVADVYQISWS 302 T H SP G + AS +V++W+ I + F G V D ISW Sbjct: 56 TEHSHQTTVAKTSPSGYYCASGDVHGNVRIWDTTQTTHILKTTIPVFSGPVKD---ISWD 112 Query: 301 ADSR---------------------------------------------LLLSGSKDSTL 257 ++S+ ++SGS D+T+ Sbjct: 113 SESKRIAAVGEGRERFGHVFLFDTGTSNGNLTGQARAMNSVDFKPSRPFRIISGSDDNTV 172 Query: 256 KVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 +++ K K H V++V ++PDG S G D + L+ Sbjct: 173 AIFEGPPFKFKSTFGEHTKFVHSVRYNPDGSLFASTGGDGTIVLY 217
>WDR31_HUMAN (Q8NA23) WD-repeat protein 31| Length = 367 Score = 67.0 bits (162), Expect = 3e-11 Identities = 42/143 (29%), Positives = 65/143 (45%), Gaps = 5/143 (3%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 S S D + +W+ S QP+ ++ GH VV + SPD L + S D ++ LW+ +TG+ Sbjct: 120 SASRDRMVMMWDLHGSSQPRQQLCGHAMVVTGLAVSPDSSQLCTGSRDNTLLLWDVVTGQ 179 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 V V + W +L S+D TL++WD R ++ P + S Sbjct: 180 SVERASVSRNVVTHLCWVPREPYILQTSEDKTLRLWDSRGLQVAHMFPAKQHIQTYCEVS 239 Query: 175 PDGEKVVS-----GGKDRALKLW 122 DG K +S GG+ LW Sbjct: 240 VDGHKCISCSNGFGGEGCEATLW 262 Score = 58.2 bits (139), Expect = 1e-08 Identities = 31/96 (32%), Positives = 51/96 (53%), Gaps = 1/96 (1%) Frame = -2 Query: 406 SASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIR-ARK 230 S DK+V +N TG V F+GH ++ +++ S S S+D + +WD+ + + Sbjct: 78 SGGKDKTVVAYNWKTGNVVKRFKGHEHEITKVACIPKSSQFFSASRDRMVMMWDLHGSSQ 137 Query: 229 LKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 +Q L GHA V + SPD ++ +G +D L LW Sbjct: 138 PRQQLCGHAMVVTGLAVSPDSSQLCTGSRDNTLLLW 173 Score = 50.8 bits (120), Expect = 2e-06 Identities = 38/140 (27%), Positives = 63/140 (45%), Gaps = 2/140 (1%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SG D T+ + K R GH+ + V P SAS D+ V +W+ + G Sbjct: 78 SGGKDKTVVAYNWKTGNVVK-RFKGHEHEITKVACIPKSSQFFSASRDRMVMMWD-LHGS 135 Query: 355 FVTAFR--GHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 182 + GH V ++ S DS L +GS+D+TL +WD+ + + + V + Sbjct: 136 SQPRQQLCGHAMVVTGLAVSPDSSQLCTGSRDNTLLLWDVVTGQSVERASVSRNVVTHLC 195 Query: 181 WSPDGEKVVSGGKDRALKLW 122 W P ++ +D+ L+LW Sbjct: 196 WVPREPYILQTSEDKTLRLW 215 Score = 35.8 bits (81), Expect = 0.078 Identities = 17/68 (25%), Positives = 32/68 (47%) Frame = -2 Query: 325 DVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGG 146 D + + +S L +SG KD T+ ++ + + + GH E+ V P + S Sbjct: 63 DTVSVVAALNSDLCVSGGKDKTVVAYNWKTGNVVKRFKGHEHEITKVACIPKSSQFFSAS 122 Query: 145 KDRALKLW 122 +DR + +W Sbjct: 123 RDRMVMMW 130
>COPB2_YEAST (P41811) Coatomer subunit beta' (Beta'-coat protein) (Beta'-COP)| Length = 889 Score = 66.6 bits (161), Expect = 4e-11 Identities = 43/142 (30%), Positives = 67/142 (47%), Gaps = 4/142 (2%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSP-DGQWLASASFDKSVKLWN-GIT 362 SGSDD T+ LW + + GH+ V V F+P D AS D++VK+W+ G + Sbjct: 114 SGSDDLTVKLWNWENNWALEQTFEGHEHFVMCVAFNPKDPSTFASGCLDRTVKVWSLGQS 173 Query: 361 GKFVTAFRGHVADVYQISWSA--DSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYA 188 T G V + + D +++ S D T+K+WD + + L GH V Sbjct: 174 TPNFTLTTGQERGVNYVDYYPLPDKPYMITASDDLTIKIWDYQTKSCVATLEGHMSNVSF 233 Query: 187 VDWSPDGEKVVSGGKDRALKLW 122 + P ++SG +D LK+W Sbjct: 234 AVFHPTLPIIISGSEDGTLKIW 255 Score = 61.6 bits (148), Expect = 1e-09 Identities = 37/127 (29%), Positives = 65/127 (51%), Gaps = 2/127 (1%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHV--YFSPDGQWLASASFDKSVKLWNGIT 362 SG D T+ +W S TG ++ VN+V Y PD ++ +AS D ++K+W+ T Sbjct: 158 SGCLDRTVKVWSLGQSTPNFTLTTGQERGVNYVDYYPLPDKPYMITASDDLTIKIWDYQT 217 Query: 361 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 182 V GH+++V + +++SGS+D TLK+W+ K+++ L + + + Sbjct: 218 KSCVATLEGHMSNVSFAVFHPTLPIIISGSEDGTLKIWNSSTYKVEKTLNVGLERSWCIA 277 Query: 181 WSPDGEK 161 P G K Sbjct: 278 THPTGRK 284 Score = 50.1 bits (118), Expect = 4e-06 Identities = 32/100 (32%), Positives = 49/100 (49%), Gaps = 2/100 (2%) Frame = -2 Query: 415 WLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRA 236 W+ S D ++++N TG+ V F H + I+ +LSGS D T+K+W+ Sbjct: 69 WIIVGSDDFRIRVFNYNTGEKVVDFEAHPDYIRSIAVHPTKPYVLSGSDDLTVKLWNWEN 128 Query: 235 R-KLKQDLPGHADEVYAVDWSP-DGEKVVSGGKDRALKLW 122 L+Q GH V V ++P D SG DR +K+W Sbjct: 129 NWALEQTFEGHEHFVMCVAFNPKDPSTFASGCLDRTVKVW 168 Score = 43.9 bits (102), Expect = 3e-04 Identities = 27/109 (24%), Positives = 47/109 (43%) Frame = -2 Query: 448 VNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSK 269 V + F P W+ + + V+LWN T V + + V + A ++ GS Sbjct: 16 VKGIDFHPTEPWVLTTLYSGRVELWNYETQVEVRSIQVTETPVRAGKFIARKNWIIVGSD 75 Query: 268 DSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 D ++V++ + D H D + ++ P V+SG D +KLW Sbjct: 76 DFRIRVFNYNTGEKVVDFEAHPDYIRSIAVHPTKPYVLSGSDDLTVKLW 124 Score = 42.7 bits (99), Expect = 6e-04 Identities = 37/142 (26%), Positives = 59/142 (41%), Gaps = 5/142 (3%) Frame = -2 Query: 532 GSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITG-K 356 GSDDF + ++ ++ H + + P ++ S S D +VKLWN Sbjct: 73 GSDDFRIRVFNYNTGEKV-VDFEAHPDYIRSIAVHPTKPYVLSGSDDLTVKLWNWENNWA 131 Query: 355 FVTAFRGHVADVYQISWS-ADSRLLLSGSKDSTLKVWDIRARKLKQDL-PGHADEVYAVD 182 F GH V ++++ D SG D T+KVW + L G V VD Sbjct: 132 LEQTFEGHEHFVMCVAFNPKDPSTFASGCLDRTVKVWSLGQSTPNFTLTTGQERGVNYVD 191 Query: 181 W--SPDGEKVVSGGKDRALKLW 122 + PD +++ D +K+W Sbjct: 192 YYPLPDKPYMITASDDLTIKIW 213
>WDR3_HUMAN (Q9UNX4) WD-repeat protein 3| Length = 943 Score = 66.6 bits (161), Expect = 4e-11 Identities = 37/114 (32%), Positives = 57/114 (50%) Frame = -2 Query: 463 GHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLL 284 GH+ V + S DG +A+ S D++VK+W G + H V + + S L Sbjct: 589 GHKLPVICMDISHDGALIATGSADRNVKIWGLDFGDCHKSLFAHDDSVMYLQFVPKSHLF 648 Query: 283 LSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 + KD +K WD + Q L GH E++ + SP G+ VVS D++L+LW Sbjct: 649 FTAGKDHKIKQWDADKFEHIQTLEGHHQEIWCLAVSPSGDYVVSSSHDKSLRLW 702 Score = 59.7 bits (143), Expect = 5e-09 Identities = 29/124 (23%), Positives = 61/124 (49%) Frame = -2 Query: 493 ISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQ 314 +S + GH+ + + + G LAS S D + +W+ I + +GH + Q Sbjct: 95 LSGEGNVTFNGHKAAITTLKYDQLGGRLASGSKDTDIIVWDVINESGLYRLKGHKDAITQ 154 Query: 313 ISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRA 134 + + LL++ KD+ +K WD+ + + + GH EV+ + + +++++G D Sbjct: 155 ALFLREKNLLVTSGKDTMVKWWDLDTQHCFKTMVGHRTEVWGLVLLSEEKRLITGASDSE 214 Query: 133 LKLW 122 L++W Sbjct: 215 LRVW 218 Score = 58.2 bits (139), Expect = 1e-08 Identities = 38/132 (28%), Positives = 66/132 (50%), Gaps = 1/132 (0%) Frame = -2 Query: 514 MFLWEPTISKQPKAR-MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFR 338 +F+W+ + K K + G ++ V + SPDG LA D S+++++ ++G+ F Sbjct: 47 VFIWD--LRKGEKILILQGLKQEVTCLCPSPDGLHLAVGYEDGSIRIFSLLSGEGNVTFN 104 Query: 337 GHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKV 158 GH A + + + L SGSKD+ + VWD+ L GH D + + + + Sbjct: 105 GHKAAITTLKYDQLGGRLASGSKDTDIIVWDVINESGLYRLKGHKDAITQALFLREKNLL 164 Query: 157 VSGGKDRALKLW 122 V+ GKD +K W Sbjct: 165 VTSGKDTMVKWW 176 Score = 55.5 bits (132), Expect = 9e-08 Identities = 32/106 (30%), Positives = 51/106 (48%) Frame = -2 Query: 439 VYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDST 260 V +SP+ + LA + D +VK++ T KF + GH V + S D L+ +GS D Sbjct: 555 VSYSPNQKLLAVSLLDCTVKIFYVDTLKFFLSLYGHKLPVICMDISHDGALIATGSADRN 614 Query: 259 LKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 +K+W + + L H D V + + P + GKD +K W Sbjct: 615 VKIWGLDFGDCHKSLFAHDDSVMYLQFVPKSHLFFTAGKDHKIKQW 660 Score = 55.1 bits (131), Expect = 1e-07 Identities = 35/130 (26%), Positives = 60/130 (46%), Gaps = 12/130 (9%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SGS D + +W+ I++ R+ GH+ + F + L ++ D VK W+ T Sbjct: 124 SGSKDTDIIVWD-VINESGLYRLKGHKDAITQALFLREKNLLVTSGKDTMVKWWDLDTQH 182 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIR------------ARKLKQDLP 212 GH +V+ + ++ + L++G+ DS L+VWDI +K+K P Sbjct: 183 CFKTMVGHRTEVWGLVLLSEEKRLITGASDSELRVWDIAYLQEIEDPEEPDPKKIKGSSP 242 Query: 211 GHADEVYAVD 182 G D + A D Sbjct: 243 GIQDTLEAED 252 Score = 51.6 bits (122), Expect = 1e-06 Identities = 36/129 (27%), Positives = 65/129 (50%), Gaps = 3/129 (2%) Frame = -2 Query: 499 PTISKQPKARMT--GHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVA 326 PT +R+T GH+ V + FS D + SA+ D S+K+WN T + R Sbjct: 399 PTPQPVRTSRITIGGHRSDVRTLSFSSDNIAVLSAAAD-SIKIWNRST---LQCIRTMTC 454 Query: 325 DVYQISWSADS-RLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSG 149 + S+ R ++ G+K L+++D+ + L + + H ++++ SPD V+G Sbjct: 455 EYALCSFFVPGDRQVVIGTKTGKLQLYDLASGNLLETIDAHDGALWSMSLSPDQRGFVTG 514 Query: 148 GKDRALKLW 122 G D+++K W Sbjct: 515 GADKSVKFW 523 Score = 50.8 bits (120), Expect = 2e-06 Identities = 34/124 (27%), Positives = 56/124 (45%), Gaps = 11/124 (8%) Frame = -2 Query: 460 HQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVA-----------DVYQ 314 H + + SPD + + DKSVK W+ K + + ++ DV Sbjct: 495 HDGALWSMSLSPDQRGFVTGGADKSVKFWDFELVKDENSTQKRLSVKQTRTLQLDEDVLC 554 Query: 313 ISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRA 134 +S+S + +LL D T+K++ + K L GH V +D S DG + +G DR Sbjct: 555 VSYSPNQKLLAVSLLDCTVKIFYVDTLKFFLSLYGHKLPVICMDISHDGALIATGSADRN 614 Query: 133 LKLW 122 +K+W Sbjct: 615 VKIW 618 Score = 39.3 bits (90), Expect = 0.007 Identities = 21/97 (21%), Positives = 44/97 (45%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 +GS D + +W K+ + H V ++ F P +A D +K W+ + Sbjct: 608 TGSADRNVKIWGLDFGDCHKS-LFAHDDSVMYLQFVPKSHLFFTAGKDHKIKQWDADKFE 666 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD 245 + GH +++ ++ S ++S S D +L++W+ Sbjct: 667 HIQTLEGHHQEIWCLAVSPSGDYVVSSSHDKSLRLWE 703
>GRWD1_RAT (Q5XI13) Glutamate-rich WD repeat-containing protein 1| Length = 445 Score = 66.2 bits (160), Expect = 5e-11 Identities = 49/153 (32%), Positives = 69/153 (45%), Gaps = 15/153 (9%) Frame = -2 Query: 535 SGSDDFTMFLWEPT------ISKQPKARMTGHQKVVNHVYFSP-DGQWLASASFDKSVKL 377 +G + LW PT + ++P GH + V + +SP + AS S D S+++ Sbjct: 231 TGDCQKNIHLWTPTDGGSWNVDQRP---FVGHTRSVEDLQWSPTEDTVFASCSADASIRI 287 Query: 376 WN--GITGK--FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDL-- 215 W+ GK +T H DV ISWS LLSG D TLKVWD+R K + Sbjct: 288 WDIRAAPGKACMLTTAAAHDGDVNVISWSRREPFLLSGGDDGTLKVWDLRQFKSGSPVAT 347 Query: 214 -PGHADEVYAVDWSP-DGEKVVSGGKDRALKLW 122 H V +V+W P D + G D + W Sbjct: 348 FKQHVAPVTSVEWHPQDSGVFAASGADNQITQW 380 Score = 32.3 bits (72), Expect = 0.86 Identities = 26/131 (19%), Positives = 45/131 (34%), Gaps = 52/131 (39%) Frame = -2 Query: 358 KFVTAFRGHVADVYQISWS----------------------------------------- 302 K + +F GH+ + + + WS Sbjct: 204 KPIFSFAGHMGEGFALDWSPRVPGRLLTGDCQKNIHLWTPTDGGSWNVDQRPFVGHTRSV 263 Query: 301 -------ADSRLLLSGSKDSTLKVWDIRARKLKQDL----PGHADEVYAVDWSPDGEKVV 155 + + S S D+++++WDIRA K + H +V + WS ++ Sbjct: 264 EDLQWSPTEDTVFASCSADASIRIWDIRAAPGKACMLTTAAAHDGDVNVISWSRREPFLL 323 Query: 154 SGGKDRALKLW 122 SGG D LK+W Sbjct: 324 SGGDDGTLKVW 334
>LIN53_CAEEL (P90916) Probable histone-binding protein lin-53 (Abnormal cell| lineage protein 53) Length = 417 Score = 66.2 bits (160), Expect = 5e-11 Identities = 46/149 (30%), Positives = 74/149 (49%), Gaps = 11/149 (7%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISK------QPKARMTGHQKVVNHV--YFSPDGQWLASASFDKSVK 380 S SDD T+ W+ ++ Q K GH+ VV V + DG + S DK + Sbjct: 190 SASDDQTVCHWDINANQNVAGELQAKDVFKGHESVVEDVAWHVLHDGVF-GSVGDDKKLL 248 Query: 379 LWNGITGKFVTAFRGHVADVYQISWSADSRLLLS-GSKDSTLKVWDIRARKLK-QDLPGH 206 +W+ T H A+V ++++ S +L+ GS D T+ +WD+R ++K H Sbjct: 249 IWDVRTSTPGHCIDAHSAEVNCLAFNPYSEFILATGSADKTVALWDLRNLRMKLHSFESH 308 Query: 205 ADEVYAVDWSPDGEKVV-SGGKDRALKLW 122 DE++ V WSP E ++ S G D+ L +W Sbjct: 309 RDEIFQVQWSPHNETILASSGTDKRLHVW 337 Score = 39.3 bits (90), Expect = 0.007 Identities = 27/82 (32%), Positives = 38/82 (46%), Gaps = 9/82 (10%) Frame = -2 Query: 340 RGHVADVYQISWSADSR-LLLSGSKDSTLKVWDIRAR-------KLKQDLPGHADEVYAV 185 +GH + Y +SW+ + L+LS S D T+ WDI A + K GH V V Sbjct: 169 KGHTKEGYGLSWNPNKEGLILSASDDQTVCHWDINANQNVAGELQAKDVFKGHESVVEDV 228 Query: 184 DWSPDGEKVV-SGGKDRALKLW 122 W + V S G D+ L +W Sbjct: 229 AWHVLHDGVFGSVGDDKKLLIW 250
>FZR_HUMAN (Q9UM11) Fizzy-related protein homolog (Fzr) (Cdh1/Hct1 homolog)| (hCDH1) (CDC20-like protein 1) Length = 496 Score = 66.2 bits (160), Expect = 5e-11 Identities = 41/134 (30%), Positives = 67/134 (50%), Gaps = 3/134 (2%) Frame = -2 Query: 514 MFLWEPTISKQPK-ARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFR 338 ++LW S+ + ++ V V +S G +A + V++W+ GK ++ Sbjct: 209 VYLWSACTSQVTRLCDLSVEGDSVTSVGWSERGNLVAVGTHKGFVQIWDAAAGKKLSMLE 268 Query: 337 GHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQD--LPGHADEVYAVDWSPDGE 164 GH A V ++W+A+ L SGS+D + DIR L+ + L GH EV + WS D + Sbjct: 269 GHTARVGALAWNAEQ--LSSGSRDRMILQRDIRTPPLQSERRLQGHRQEVCGLKWSTDHQ 326 Query: 163 KVVSGGKDRALKLW 122 + SGG D L +W Sbjct: 327 LLASGGNDNKLLVW 340 Score = 59.7 bits (143), Expect = 5e-09 Identities = 39/143 (27%), Positives = 68/143 (47%), Gaps = 5/143 (3%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASA---SFDKSVKLWNGI 365 SG +D + +W + S P + T H V + +SP L ++ + D+ ++ WN + Sbjct: 330 SGGNDNKLLVWNHS-SLSPVQQYTEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTL 388 Query: 364 TGKFVTAFRGHVADVYQISWSADSRLLLS--GSKDSTLKVWDIRARKLKQDLPGHADEVY 191 TG+ + + V ++WS + L+S G + + VW + L GH+ V Sbjct: 389 TGQPLQCIDTG-SQVCNLAWSKHANELVSTHGYSQNQILVWKYPSLTQVAKLTGHSYRVL 447 Query: 190 AVDWSPDGEKVVSGGKDRALKLW 122 + SPDGE +V+G D L+ W Sbjct: 448 YLAMSPDGEAIVTGAGDETLRFW 470 Score = 49.3 bits (116), Expect = 7e-06 Identities = 25/76 (32%), Positives = 38/76 (50%), Gaps = 3/76 (3%) Frame = -2 Query: 340 RGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEK 161 +GH +V + WS D +LL SG D+ L VW+ + Q H V A+ WSP Sbjct: 310 QGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQYTEHLAAVKAIAWSPHQHG 369 Query: 160 VVSGG---KDRALKLW 122 +++ G DR ++ W Sbjct: 370 LLASGGGTADRCIRFW 385 Score = 39.7 bits (91), Expect = 0.005 Identities = 26/94 (27%), Positives = 40/94 (42%), Gaps = 2/94 (2%) Frame = -2 Query: 406 SASFDKSVKLWNGITGKFVTAFRGHVA--DVYQISWSADSRLLLSGSKDSTLKVWDIRAR 233 S V LW+ T + V V + WS L+ G+ +++WD A Sbjct: 202 SVGLGTCVYLWSACTSQVTRLCDLSVEGDSVTSVGWSERGNLVAVGTHKGFVQIWDAAAG 261 Query: 232 KLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRAL 131 K L GH V A+ W + E++ SG +DR + Sbjct: 262 KKLSMLEGHTARVGALAW--NAEQLSSGSRDRMI 293 Score = 33.5 bits (75), Expect = 0.38 Identities = 12/35 (34%), Positives = 24/35 (68%) Frame = -2 Query: 475 ARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWN 371 A++TGH V ++ SPDG+ + + + D++++ WN Sbjct: 437 AKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWN 471
>PRP17_MOUSE (Q9DC48) Pre-mRNA-splicing factor PRP17 (Cell division cycle 40| homolog) Length = 579 Score = 66.2 bits (160), Expect = 5e-11 Identities = 38/141 (26%), Positives = 69/141 (48%), Gaps = 3/141 (2%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 S S D + LWE ++ GH K V + F+ G SA++D+ +KLW+ TG+ Sbjct: 306 SCSMDCKIKLWEVYGDRRCLRTFIGHSKAVRDICFNTAGTQFLSAAYDRYLKLWDTETGQ 365 Query: 355 FVTAFRGHVADVYQISWSAD---SRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAV 185 ++ F Y + ++ D L ++G D + WDIR+ ++ Q+ H V + Sbjct: 366 CISRFTNRKVP-YCVKFNPDEDKQNLFVAGMSDKKIVQWDIRSGEIVQEYDRHLGAVNTI 424 Query: 184 DWSPDGEKVVSGGKDRALKLW 122 + + + VS D++L++W Sbjct: 425 VFVDENRRFVSTSDDKSLRVW 445 Score = 62.8 bits (151), Expect = 6e-10 Identities = 43/145 (29%), Positives = 66/145 (45%), Gaps = 7/145 (4%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 S SDD ++ +WE I K + V SP+G+WLA S D + ++ G + Sbjct: 435 STSDDKSLRVWEWDIPVDFKYIAEPSMHSMPAVTLSPNGKWLACQSMDNQILIF-GAQNR 493 Query: 355 F----VTAFRGHVADVY--QISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEV 194 F F+GH+ Y Q+ +S D ++SG + L +WD + KL H Sbjct: 494 FRLNKKKIFKGHMVAGYACQVDFSPDMSYVISGDGNGKLNIWDWKTTKLYSRFKAHDKVC 553 Query: 193 YAVDWSP-DGEKVVSGGKDRALKLW 122 W P + KV++ G D +KLW Sbjct: 554 IGAVWHPHETSKVITCGWDGLIKLW 578 Score = 40.4 bits (93), Expect = 0.003 Identities = 29/91 (31%), Positives = 48/91 (52%), Gaps = 1/91 (1%) Frame = -2 Query: 391 KSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRA-RKLKQDL 215 K + +W+G T K V+A R ++ +S LLLS S D +K+W++ R+ + Sbjct: 279 KQIHVWSGHT-KGVSAVR-----LFPLS----GHLLLSCSMDCKIKLWEVYGDRRCLRTF 328 Query: 214 PGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 GH+ V + ++ G + +S DR LKLW Sbjct: 329 IGHSKAVRDICFNTAGTQFLSAAYDRYLKLW 359
>PRP17_HUMAN (O60508) Pre-mRNA-splicing factor PRP17 (hPRP17) (Cell division| cycle 40 homolog) (EH-binding protein 3) (Ehb3) Length = 579 Score = 66.2 bits (160), Expect = 5e-11 Identities = 38/141 (26%), Positives = 69/141 (48%), Gaps = 3/141 (2%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 S S D + LWE ++ GH K V + F+ G SA++D+ +KLW+ TG+ Sbjct: 306 SCSMDCKIKLWEVYGERRCLRTFIGHSKAVRDICFNTAGTQFLSAAYDRYLKLWDTETGQ 365 Query: 355 FVTAFRGHVADVYQISWSAD---SRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAV 185 ++ F Y + ++ D L ++G D + WDIR+ ++ Q+ H V + Sbjct: 366 CISRFTNRKVP-YCVKFNPDEDKQNLFVAGMSDKKIVQWDIRSGEIVQEYDRHLGAVNTI 424 Query: 184 DWSPDGEKVVSGGKDRALKLW 122 + + + VS D++L++W Sbjct: 425 VFVDENRRFVSTSDDKSLRVW 445 Score = 62.8 bits (151), Expect = 6e-10 Identities = 43/145 (29%), Positives = 66/145 (45%), Gaps = 7/145 (4%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 S SDD ++ +WE I K + V SP+G+WLA S D + ++ G + Sbjct: 435 STSDDKSLRVWEWDIPVDFKYIAEPSMHSMPAVTLSPNGKWLACQSMDNQILIF-GAQNR 493 Query: 355 F----VTAFRGHVADVY--QISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEV 194 F F+GH+ Y Q+ +S D ++SG + L +WD + KL H Sbjct: 494 FRLNKKKIFKGHMVAGYACQVDFSPDMSYVISGDGNGKLNIWDWKTTKLYSRFKAHDKVC 553 Query: 193 YAVDWSP-DGEKVVSGGKDRALKLW 122 W P + KV++ G D +KLW Sbjct: 554 IGAVWHPHETSKVITCGWDGLIKLW 578 Score = 40.4 bits (93), Expect = 0.003 Identities = 29/91 (31%), Positives = 48/91 (52%), Gaps = 1/91 (1%) Frame = -2 Query: 391 KSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRA-RKLKQDL 215 K + +W+G T K V+A R ++ +S LLLS S D +K+W++ R+ + Sbjct: 279 KQIHVWSGHT-KGVSAVR-----LFPLS----GHLLLSCSMDCKIKLWEVYGERRCLRTF 328 Query: 214 PGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 GH+ V + ++ G + +S DR LKLW Sbjct: 329 IGHSKAVRDICFNTAGTQFLSAAYDRYLKLW 359
>GBB_DICDI (P36408) Guanine nucleotide-binding protein beta subunit| Length = 347 Score = 65.9 bits (159), Expect = 7e-11 Identities = 36/116 (31%), Positives = 60/116 (51%) Frame = -2 Query: 469 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 290 + H ++ F D Q + ++S D + LW+ G +T F H DV +S S D Sbjct: 146 LNSHTGYLSCCRFLNDRQ-IVTSSGDMTCILWDVENGTKITEFSDHNGDVMSVSVSPDKN 204 Query: 289 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 +SG+ D+T K+WD+R+ K Q GH ++ AV + P+G +G D + +L+ Sbjct: 205 YFISGACDATAKLWDLRSGKCVQTFTGHEADINAVQYFPNGLSFGTGSDDASCRLF 260 Score = 57.0 bits (136), Expect = 3e-08 Identities = 38/140 (27%), Positives = 63/140 (45%), Gaps = 2/140 (1%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SG+ D T LW+ K + TGH+ +N V + P+G + S D S +L++ + Sbjct: 208 SGACDATAKLWDLRSGKCVQT-FTGHEADINAVQYFPNGLSFGTGSDDASCRLFDIRADR 266 Query: 355 FVTAFRGH--VADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVD 182 + + + + + +S R L +G D T VWD + L GH + V + Sbjct: 267 ELMQYTHDNILCGITSVGFSFSGRFLFAGYDDFTCNVWDTLKGERVLSLTGHGNRVSCLG 326 Query: 181 WSPDGEKVVSGGKDRALKLW 122 DG + +G D LK+W Sbjct: 327 VPTDGMALCTGSWDSLLKIW 346 Score = 56.2 bits (134), Expect = 6e-08 Identities = 41/141 (29%), Positives = 68/141 (48%), Gaps = 3/141 (2%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPK-ARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITG 359 + S D T LW+ + K + H V V SPD + S + D + KLW+ +G Sbjct: 166 TSSGDMTCILWD--VENGTKITEFSDHNGDVMSVSVSPDKNYFISGACDATAKLWDLRSG 223 Query: 358 KFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRA-RKLKQDLPGH-ADEVYAV 185 K V F GH AD+ + + + +GS D++ +++DIRA R+L Q + + +V Sbjct: 224 KCVQTFTGHEADINAVQYFPNGLSFGTGSDDASCRLFDIRADRELMQYTHDNILCGITSV 283 Query: 184 DWSPDGEKVVSGGKDRALKLW 122 +S G + +G D +W Sbjct: 284 GFSFSGRFLFAGYDDFTCNVW 304 Score = 44.3 bits (103), Expect = 2e-04 Identities = 22/73 (30%), Positives = 35/73 (47%) Frame = -2 Query: 340 RGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEK 161 +GH+A +Y + W+ D+ L+S S+D L VWD +P + V +SP Sbjct: 59 KGHLAKIYAMHWAEDNVHLVSASQDGKLLVWDGLTTNKVHAIPLRSSWVMTCAYSPTANF 118 Query: 160 VVSGGKDRALKLW 122 V GG D ++ Sbjct: 119 VACGGLDNICSIY 131 Score = 39.7 bits (91), Expect = 0.005 Identities = 28/123 (22%), Positives = 57/123 (46%), Gaps = 4/123 (3%) Frame = -2 Query: 478 KARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSA 299 + + GH + ++++ D L SAS D + +W+G+T V A + V ++S Sbjct: 55 RRNLKGHLAKIYAMHWAEDNVHLVSASQDGKLLVWDGLTTNKVHAIPLRSSWVMTCAYSP 114 Query: 298 DSRLLLSGSKDSTLKVWDIRAR----KLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRAL 131 + + G D+ ++++R+R ++ ++L H + + D + V S G D Sbjct: 115 TANFVACGGLDNICSIYNLRSREQPIRVCRELNSHTGYLSCCRFLNDRQIVTSSG-DMTC 173 Query: 130 KLW 122 LW Sbjct: 174 ILW 176 Score = 35.4 bits (80), Expect = 0.10 Identities = 13/37 (35%), Positives = 24/37 (64%) Frame = -2 Query: 232 KLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 K++++L GH ++YA+ W+ D +VS +D L +W Sbjct: 53 KVRRNLKGHLAKIYAMHWAEDNVHLVSASQDGKLLVW 89
>WDR1_DROME (Q9VU68) Putative actin-interacting protein 1 (AIP1)| Length = 608 Score = 65.9 bits (159), Expect = 7e-11 Identities = 38/105 (36%), Positives = 59/105 (56%), Gaps = 2/105 (1%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 +GS+D T+ ++E K K H + V V +SPDG++ ASA FD V L++G + + Sbjct: 170 TGSEDNTIAVFEGPPFKF-KMTKQDHSRFVQAVRYSPDGKFFASAGFDGKVFLYDGTSSE 228 Query: 355 FVTAF--RGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKL 227 V F H VY ++W DS LL+ S D T ++W + +R+L Sbjct: 229 LVGEFGSPAHKGGVYALAWKPDSTQLLTCSGDKTCRLWTVESREL 273 Score = 50.1 bits (118), Expect = 4e-06 Identities = 29/119 (24%), Positives = 56/119 (47%), Gaps = 3/119 (2%) Frame = -2 Query: 469 MTGHQKVVNHVYFSPDGQW-LASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADS 293 ++G K +N F P + + + S D ++ ++ G KF + H V + +S D Sbjct: 148 ISGQSKSINSADFRPARPFRIVTGSEDNTIAVFEGPPFKFKMTKQDHSRFVQAVRYSPDG 207 Query: 292 RLLLSGSKDSTLKVWDIRARKLKQDL--PGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 + S D + ++D + +L + P H VYA+ W PD ++++ D+ +LW Sbjct: 208 KFFASAGFDGKVFLYDGTSSELVGEFGSPAHKGGVYALAWKPDSTQLLTCSGDKTCRLW 266 Score = 45.8 bits (107), Expect = 7e-05 Identities = 36/126 (28%), Positives = 62/126 (49%), Gaps = 5/126 (3%) Frame = -2 Query: 484 QPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFV--TAFRGHVADVYQI 311 +PK + H V V +SPD ++L + + V L++ K + H A V + Sbjct: 481 EPKVELD-HLGAVTDVSYSPDLKYLVACDAHRKVVLYSVEEYKPAHNKEWGFHSARVNTV 539 Query: 310 SWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHA---DEVYAVDWSPDGEKVVSGGKD 140 +WS +S L+ SGS D+T+ +W + A K + +A ++ + W D V+S G+D Sbjct: 540 AWSPNSLLVASGSLDTTIIIWSV-ANPAKHTIIKNAHPQSQITRLVWL-DNNTVISTGQD 597 Query: 139 RALKLW 122 K+W Sbjct: 598 CNTKVW 603 Score = 41.6 bits (96), Expect = 0.001 Identities = 35/162 (21%), Positives = 62/162 (38%), Gaps = 47/162 (29%) Frame = -2 Query: 466 TGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFV--TAFRGHVADVYQISWSADS 293 T H VN +SP G ++AS +++W+ + + + F+ + ISWS D+ Sbjct: 61 TEHSCAVNVAKYSPSGFYIASGDASGKIRIWDTVNKEHLLKNEFQPIAGPIKDISWSPDN 120 Query: 292 R---------------------------------------------LLLSGSKDSTLKVW 248 + +++GS+D+T+ V+ Sbjct: 121 QRIVAVGEGRERFGHVFMSETGTSVGEISGQSKSINSADFRPARPFRIVTGSEDNTIAVF 180 Query: 247 DIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 + K K H+ V AV +SPDG+ S G D + L+ Sbjct: 181 EGPPFKFKMTKQDHSRFVQAVRYSPDGKFFASAGFDGKVFLY 222 Score = 36.6 bits (83), Expect = 0.045 Identities = 38/143 (26%), Positives = 63/143 (44%), Gaps = 5/143 (3%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQP-KARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITG 359 S D +FL++ T S+ + H+ V + + PD L + S DK+ +LW + Sbjct: 212 SAGFDGKVFLYDGTSSELVGEFGSPAHKGGVYALAWKPDSTQLLTCSGDKTCRLWTVESR 271 Query: 358 KFVTAF-RGHVADVYQIS--WSADSRLLLSGSKDST-LKVWDIRARKLKQDLPGHADEVY 191 + V+ F G D Q+S W D+ + +S S T L V D K + + GH + Sbjct: 272 ELVSEFVMGTTVDDQQVSCLWQGDNLITVSLSGVITYLNVAD--PSKPLRVVKGHNKPIT 329 Query: 190 AVDWSPDGEKVVSGGKDRALKLW 122 + S D + +G D + W Sbjct: 330 VLGLSDDRSTIYTGSHDGVVTNW 352
>HAT2_USTMA (Q4P553) Histone acetyltransferase type B subunit 2 (EC 2.3.1.48)| Length = 485 Score = 65.9 bits (159), Expect = 7e-11 Identities = 45/150 (30%), Positives = 75/150 (50%), Gaps = 12/150 (8%) Frame = -2 Query: 535 SGSDDFTMFLWE------PTISKQPKARMTGHQKVVNHVYFSPDGQWL-ASASFDKSVKL 377 + S+D T+ W+ P + QP A TGH +V V + + L S D+ + + Sbjct: 259 AASEDTTVCHWDINNYTKPNNTLQPSATYTGHTAIVEDVAWHNHHESLFGSVGDDRQLLI 318 Query: 376 WNGITGKFVTAFR--GHVADVYQISWSADSR-LLLSGSKDSTLKVWDIRARKLK-QDLPG 209 W+ +R H +V +++S ++ +L++GS D ++ VWD+R K+K L Sbjct: 319 WDIREPASAPKYRVEAHTGEVNALAFSPENENILVTGSSDKSVGVWDLRNLKVKLHSLES 378 Query: 208 HADEVYAVDWSPDGEKVV-SGGKDRALKLW 122 H DE+ +V WSP V+ S DR + LW Sbjct: 379 HTDEILSVCWSPHHATVLASASADRRVNLW 408 Score = 30.8 bits (68), Expect = 2.5 Identities = 27/112 (24%), Positives = 46/112 (41%), Gaps = 16/112 (14%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPD-GQWLASASFDKSVKLWN---- 371 +GS D ++ +W+ K + H + V +SP LASAS D+ V LW+ Sbjct: 354 TGSSDKSVGVWDLRNLKVKLHSLESHTDEILSVCWSPHHATVLASASADRRVNLWDLSKI 413 Query: 370 ----------GITGKFVTAFRGHVADVYQISWSADSR-LLLSGSKDSTLKVW 248 + + GH + ++WS L S ++D+ + VW Sbjct: 414 GQEQTPDDAEDGPPELIFVHGGHTSRPTDLAWSPHMEWALTSAAEDNIVMVW 465
>HIRA_FUGRU (O42611) HIRA protein (TUP1-like enhancer of split protein 1)| Length = 1025 Score = 65.9 bits (159), Expect = 7e-11 Identities = 49/168 (29%), Positives = 73/168 (43%), Gaps = 31/168 (18%) Frame = -2 Query: 532 GSDDFTMFLWE--PTISKQ-------PK--ARMTGHQKVVNHVYFSPDGQWLASASFDKS 386 G D + +W P + ++ PK +M H VN V +S +G +LAS DK Sbjct: 34 GEDSGKVMIWNMAPVLKEEDEKNENVPKMLCQMDNHLACVNCVRWSNNGLYLASGGDDKL 93 Query: 385 VKLWN-----------GITGKF--------VTAFRGHVADVYQISWSADSRLLLSGSKDS 263 V +W G + K VT R H DV +SWS L S S D+ Sbjct: 94 VMVWKRAALIGPSTVFGSSNKLANVEQWRCVTILRNHTGDVMDVSWSPHDVWLASCSVDN 153 Query: 262 TLKVWDIRA-RKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 T+ +W+ R ++ L GH V + W P G+ + S D +L++W Sbjct: 154 TIVIWNARKFPEMVTCLRGHTGLVKGLTWDPVGKYIASQADDHSLRVW 201 Score = 46.6 bits (109), Expect = 4e-05 Identities = 41/168 (24%), Positives = 71/168 (42%), Gaps = 29/168 (17%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWN----- 371 S S D T+ +W + + GH +V + + P G+++AS + D S+++W Sbjct: 148 SCSVDNTIVIWNARKFPEMVTCLRGHTGLVKGLTWDPVGKYIASQADDHSLRVWRTVDWQ 207 Query: 370 ---GITGKFVTAFRGHVADVYQISWSADSRLLLS----GSKDSTLKVWDIRARKLKQDLP 212 IT F G V ++SWS D + L+S + T ++ + + D Sbjct: 208 MEANITKPFSEC--GGTTHVLRLSWSPDGQYLVSAHAMNNSGPTAQIVERDGWRTNMDFV 265 Query: 211 GHADEVYAVDWSPD--GEKVVSGG---------------KDRALKLWM 119 GH V V ++P +K +GG KDR+L +W+ Sbjct: 266 GHRKAVTVVKFNPKIFKKKQKNGGSPKPSCPYCCCAVGSKDRSLSVWL 313
>POP2_SCHPO (O14170) WD-repeat protein pop2 (Proteolysis factor sud1)| Length = 703 Score = 65.9 bits (159), Expect = 7e-11 Identities = 41/138 (29%), Positives = 68/138 (49%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SGS D ++ +W + + + GH + V + P+ S S DKS+++W+ TG Sbjct: 522 SGSYDSSIRIWRVSTG-ECLYHLRGHSLRIYSVLYEPERNICISGSMDKSIRVWDLSTGT 580 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 GH D + + L+SGS DST+++WD+ K LP ++ Y + Sbjct: 581 CKYVLEGH--DAFVTLLNVFQNRLISGSADSTIRIWDLNTGKPLMVLPSNSG--YISSFV 636 Query: 175 PDGEKVVSGGKDRALKLW 122 D K++S G D ++KLW Sbjct: 637 SDEHKIIS-GNDGSVKLW 653 Score = 65.1 bits (157), Expect = 1e-10 Identities = 32/116 (27%), Positives = 59/116 (50%) Frame = -2 Query: 469 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 290 + GH V + S G L S S+D S+++W TG+ + RGH +Y + + + Sbjct: 503 LIGHTDSVRTI--SGYGDILVSGSYDSSIRIWRVSTGECLYHLRGHSLRIYSVLYEPERN 560 Query: 289 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 + +SGS D +++VWD+ K L GH + + + +++SG D +++W Sbjct: 561 ICISGSMDKSIRVWDLSTGTCKYVLEGH--DAFVTLLNVFQNRLISGSADSTIRIW 614 Score = 53.1 bits (126), Expect = 5e-07 Identities = 43/153 (28%), Positives = 67/153 (43%), Gaps = 34/153 (22%) Frame = -2 Query: 478 KARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSA 299 +AR+ GH++ V V + L S S DK+V++WN K FRGH++ + + Sbjct: 384 EARLEGHKEGVWAVKIHENT--LVSGSIDKTVRVWNIEKAKCTHIFRGHISIIRCLEILV 441 Query: 298 DSRL--------------LLSGSKDSTLKVWDIRARKLKQDLP----------------- 212 SRL ++SGS+D TL+VW + LP Sbjct: 442 PSRLIRHGVEIVEPDQPYIVSGSRDHTLRVWKLPKNTDPPYLPDNTNSIDRWEKNPYFVH 501 Query: 211 ---GHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 GH D V + S G+ +VSG D ++++W Sbjct: 502 TLIGHTDSVRTI--SGYGDILVSGSYDSSIRIW 532
>GBB_SOLTU (P93563) Guanine nucleotide-binding protein beta subunit| Length = 377 Score = 65.9 bits (159), Expect = 7e-11 Identities = 43/147 (29%), Positives = 67/147 (45%), Gaps = 9/147 (6%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SGS D T LW+ ++ + + GH+ VN V F PDG + S D S +L++ TG Sbjct: 222 SGSCDTTARLWDTRVASRAQRTFHGHESDVNTVKFFPDGNRFGTGSDDGSCRLFDIRTGH 281 Query: 355 FVTAFR-----GHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDL----PGHA 203 + + G + V +++S RLL G + VWD K+ +L H Sbjct: 282 QLQVYNQPHGDGDIPHVTSMAFSISGRLLFVGYSNGDCYVWDTLLAKVVLNLGSVQNSHE 341 Query: 202 DEVYAVDWSPDGEKVVSGGKDRALKLW 122 + + S DG + +G D LK+W Sbjct: 342 GRISCLGLSADGSALCTGSWDTNLKIW 368 Score = 65.1 bits (157), Expect = 1e-10 Identities = 43/129 (33%), Positives = 72/129 (55%), Gaps = 9/129 (6%) Frame = -2 Query: 481 PKARM-TGHQKVVNHVYFSPDGQW-LASASFDKSVKLWNGITGKFVTAF-----RGHVAD 323 P +RM +GH+ V+ + PD L ++S D++ LW+ TG + F GH AD Sbjct: 147 PVSRMLSGHKGYVSSCQYVPDEDTHLITSSGDQTCVLWDITTGLRTSVFGGEFQSGHTAD 206 Query: 322 VYQISWSADS-RLLLSGSKDSTLKVWDIR-ARKLKQDLPGHADEVYAVDWSPDGEKVVSG 149 V +S S+ + +L +SGS D+T ++WD R A + ++ GH +V V + PDG + +G Sbjct: 207 VLSVSISSSNPKLFVSGSCDTTARLWDTRVASRAQRTFHGHESDVNTVKFFPDGNRFGTG 266 Query: 148 GKDRALKLW 122 D + +L+ Sbjct: 267 SDDGSCRLF 275 Score = 42.4 bits (98), Expect = 8e-04 Identities = 20/73 (27%), Positives = 34/73 (46%) Frame = -2 Query: 340 RGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEK 161 +GH VY + W+ + ++S S+D L VW+ + + V +SP G+ Sbjct: 62 QGHTGKVYSLDWTPEKNRIVSASQDGRLIVWNALTSQKTHAIKLPCAWVMTCAFSPSGQS 121 Query: 160 VVSGGKDRALKLW 122 V GG D A ++ Sbjct: 122 VACGGLDSACSIF 134 Score = 38.9 bits (89), Expect = 0.009 Identities = 27/124 (21%), Positives = 56/124 (45%), Gaps = 8/124 (6%) Frame = -2 Query: 469 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 290 + GH V + ++P+ + SAS D + +WN +T + A + A V ++S + Sbjct: 61 LQGHTGKVYSLDWTPEKNRIVSASQDGRLIVWNALTSQKTHAIKLPCAWVMTCAFSPSGQ 120 Query: 289 LLLSGSKDSTLKVWDIRA-------RKLKQDLPGHADEVYAVDWSPDGE-KVVSGGKDRA 134 + G DS ++++ + + + L GH V + + PD + +++ D+ Sbjct: 121 SVACGGLDSACSIFNLNSPIDKDGIHPVSRMLSGHKGYVSSCQYVPDEDTHLITSSGDQT 180 Query: 133 LKLW 122 LW Sbjct: 181 CVLW 184
>GBB1_TOBAC (P93397) Guanine nucleotide-binding protein beta subunit 1| Length = 377 Score = 65.9 bits (159), Expect = 7e-11 Identities = 44/129 (34%), Positives = 72/129 (55%), Gaps = 9/129 (6%) Frame = -2 Query: 481 PKARM-TGHQKVVNHVYFSPDGQW-LASASFDKSVKLWNGITGKFVTAF-----RGHVAD 323 P +RM +GH+ V+ + PD L ++S D++ LW+ TG + F GH AD Sbjct: 147 PVSRMLSGHKGYVSSCQYVPDEDTHLITSSGDQTCVLWDITTGLRTSVFGGEFQSGHTAD 206 Query: 322 VYQISWSADS-RLLLSGSKDSTLKVWDIR-ARKLKQDLPGHADEVYAVDWSPDGEKVVSG 149 V +S S+ + RL +SGS D+T ++WD R A + ++ GH +V V + PDG + +G Sbjct: 207 VQSVSISSSNPRLFVSGSCDTTARLWDTRVASRAQRTFYGHEGDVNTVKFFPDGNRFGTG 266 Query: 148 GKDRALKLW 122 +D +L+ Sbjct: 267 SEDGTCRLF 275 Score = 62.4 bits (150), Expect = 8e-10 Identities = 42/147 (28%), Positives = 67/147 (45%), Gaps = 9/147 (6%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SGS D T LW+ ++ + + GH+ VN V F PDG + S D + +L++ T Sbjct: 222 SGSCDTTARLWDTRVASRAQRTFYGHEGDVNTVKFFPDGNRFGTGSEDGTCRLFDIRTEH 281 Query: 355 FVTAF-----RGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPG----HA 203 + + G + V +++S RLL G + VWD K+ +L G H Sbjct: 282 QLQVYYQPHGDGDIPHVTSMAFSISGRLLFVGYSNGDCYVWDTLLAKVVLNLGGVQNSHE 341 Query: 202 DEVYAVDWSPDGEKVVSGGKDRALKLW 122 + + S DG + +G D LK+W Sbjct: 342 GRISCLGLSADGSALCTGSWDTNLKIW 368 Score = 40.8 bits (94), Expect = 0.002 Identities = 19/73 (26%), Positives = 33/73 (45%) Frame = -2 Query: 340 RGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEK 161 +GH VY + W+ + ++S S+D L VW+ + + V +SP G+ Sbjct: 62 QGHTGKVYSLDWTPEKNRIVSASQDGRLIVWNALTSQKTHAIKLPCAWVMTCAFSPSGQS 121 Query: 160 VVSGGKDRALKLW 122 V GG D ++ Sbjct: 122 VACGGLDSVCSIF 134 Score = 38.9 bits (89), Expect = 0.009 Identities = 27/124 (21%), Positives = 56/124 (45%), Gaps = 8/124 (6%) Frame = -2 Query: 469 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 290 + GH V + ++P+ + SAS D + +WN +T + A + A V ++S + Sbjct: 61 LQGHTGKVYSLDWTPEKNRIVSASQDGRLIVWNALTSQKTHAIKLPCAWVMTCAFSPSGQ 120 Query: 289 LLLSGSKDSTLKVWDIRA-------RKLKQDLPGHADEVYAVDWSPDGE-KVVSGGKDRA 134 + G DS ++++ + + + L GH V + + PD + +++ D+ Sbjct: 121 SVACGGLDSVCSIFNLNSPIDKDGNHPVSRMLSGHKGYVSSCQYVPDEDTHLITSSGDQT 180 Query: 133 LKLW 122 LW Sbjct: 181 CVLW 184
>PFS2_YEAST (P42841) Protein PFS2| Length = 465 Score = 65.9 bits (159), Expect = 7e-11 Identities = 31/116 (26%), Positives = 54/116 (46%) Frame = -2 Query: 469 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 290 M H V + +S D W+ S D +K+W H + +++S++ Sbjct: 131 MQAHDSAVTTMKYSHDSDWMISGDADGMIKIWQPNFSMVKEIDAAHTESIRDMAFSSNDS 190 Query: 289 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 ++ S D+ LK+W+ K ++ L GH +V + DW P+ + S KD +KLW Sbjct: 191 KFVTCSDDNILKIWNFSNGKQERVLSGHHWDVKSCDWHPEMGLIASASKDNLVKLW 246 Score = 60.1 bits (144), Expect = 4e-09 Identities = 29/110 (26%), Positives = 55/110 (50%) Frame = -2 Query: 451 VVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGS 272 V+ + ++P+G+ L A++ LWN + F T + H + V + +S DS ++SG Sbjct: 95 VIPAIQWTPEGRRLVVATYSGEFSLWNASSFTFETLMQAHDSAVTTMKYSHDSDWMISGD 154 Query: 271 KDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 D +K+W +K+ H + + + +S + K V+ D LK+W Sbjct: 155 ADGMIKIWQPNFSMVKEIDAAHTESIRDMAFSSNDSKFVTCSDDNILKIW 204 Score = 57.4 bits (137), Expect = 2e-08 Identities = 36/139 (25%), Positives = 62/139 (44%), Gaps = 1/139 (0%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SG D + +W+P S K H + + + FS + + S D +K+WN GK Sbjct: 152 SGDADGMIKIWQPNFS-MVKEIDAAHTESIRDMAFSSNDSKFVTCSDDNILKIWNFSNGK 210 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 GH DV W + L+ S SKD+ +K+WD R+ + V + Sbjct: 211 QERVLSGHHWDVKSCDWHPEMGLIASASKDNLVKLWDPRSGNCISSILKFKHTVLKTRFQ 270 Query: 175 P-DGEKVVSGGKDRALKLW 122 P G +++ KD++ +++ Sbjct: 271 PTKGNLLMAISKDKSCRVF 289
>HIRL_SCHPO (P87314) Histone transcription regulator 1 homolog| Length = 932 Score = 65.5 bits (158), Expect = 9e-11 Identities = 39/134 (29%), Positives = 65/134 (48%), Gaps = 18/134 (13%) Frame = -2 Query: 469 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWN------GITGKFVTAFR---------- 338 M+ H V V FSP+GQ+LAS S D+ V +W+ G+ F + + Sbjct: 70 MSTHTGTVTSVRFSPNGQYLASGSDDRVVIIWHKEEAIPGLGSTFGSGEKHTENWRSYRR 129 Query: 337 --GHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGE 164 GH D+ + WS DS+L++S DS++ VW+ + + + H V + + P G+ Sbjct: 130 LLGHDNDIQDLCWSYDSQLVVSVGLDSSIIVWNGTTFERLKRIEAHQSHVKGITFDPAGK 189 Query: 163 KVVSGGKDRALKLW 122 + DR +K+W Sbjct: 190 YFATESDDRTIKVW 203 Score = 55.1 bits (131), Expect = 1e-07 Identities = 35/151 (23%), Positives = 63/151 (41%), Gaps = 23/151 (15%) Frame = -2 Query: 535 SGSDDFTMFLWEP-----------------TISKQPKARMTGHQKVVNHVYFSPDGQWLA 407 SGSDD + +W T + + R+ GH + + +S D Q + Sbjct: 91 SGSDDRVVIIWHKEEAIPGLGSTFGSGEKHTENWRSYRRLLGHDNDIQDLCWSYDSQLVV 150 Query: 406 SASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKL 227 S D S+ +WNG T + + H + V I++ + + S D T+KVW + + Sbjct: 151 SVGLDSSIIVWNGTTFERLKRIEAHQSHVKGITFDPAGKYFATESDDRTIKVWRVSDFSI 210 Query: 226 KQDLPGHADE------VYAVDWSPDGEKVVS 152 ++ + G + WSPDG+ + + Sbjct: 211 EKTITGPFNNSPLSTYFRRPSWSPDGKHIAA 241 Score = 45.1 bits (105), Expect = 1e-04 Identities = 31/146 (21%), Positives = 58/146 (39%), Gaps = 32/146 (21%) Frame = -2 Query: 463 GHQKVVNHVYFSPDGQWLASASFDKSVKLW--------------NGITGKFVTAFRGHVA 326 GH+ + ++ PDG +A+ D ++++W N K + H Sbjct: 16 GHRLSIFSIHIHPDGSRIATGGLDGTIRIWSTEAINRENENENENEDLPKQLCCMSTHTG 75 Query: 325 DVYQISWSADSRLLLSGSKDSTLKVWDIRAR------------------KLKQDLPGHAD 200 V + +S + + L SGS D + +W + + L GH + Sbjct: 76 TVTSVRFSPNGQYLASGSDDRVVIIWHKEEAIPGLGSTFGSGEKHTENWRSYRRLLGHDN 135 Query: 199 EVYAVDWSPDGEKVVSGGKDRALKLW 122 ++ + WS D + VVS G D ++ +W Sbjct: 136 DIQDLCWSYDSQLVVSVGLDSSIIVW 161 Score = 43.1 bits (100), Expect = 5e-04 Identities = 37/153 (24%), Positives = 67/153 (43%), Gaps = 19/153 (12%) Frame = -2 Query: 523 DFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWN----GITGK 356 D ++ +W T ++ K R+ HQ V + F P G++ A+ S D+++K+W I Sbjct: 155 DSSIIVWNGTTFERLK-RIEAHQSHVKGITFDPAGKYFATESDDRTIKVWRVSDFSIEKT 213 Query: 355 FVTAFRGHVADVY--QISWSADSRLLLS----GSKDSTLKVWDIRARKLKQDLPGHADEV 194 F Y + SWS D + + + S + + + + +L GH V Sbjct: 214 ITGPFNNSPLSTYFRRPSWSPDGKHIAAPNAMNGPVSCVSIIERGTWTSEINLIGHEGPV 273 Query: 193 YAVDWSPD-----GEKVVS----GGKDRALKLW 122 ++P +K+V GG+DR+L +W Sbjct: 274 EVTAFNPKLFRDKNDKLVCILACGGQDRSLSIW 306 Score = 43.1 bits (100), Expect = 5e-04 Identities = 24/87 (27%), Positives = 39/87 (44%), Gaps = 14/87 (16%) Frame = -2 Query: 340 RGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRA-------RKLKQDLP-------GHA 203 RGH ++ I D + +G D T+++W A +DLP H Sbjct: 15 RGHRLSIFSIHIHPDGSRIATGGLDGTIRIWSTEAINRENENENENEDLPKQLCCMSTHT 74 Query: 202 DEVYAVDWSPDGEKVVSGGKDRALKLW 122 V +V +SP+G+ + SG DR + +W Sbjct: 75 GTVTSVRFSPNGQYLASGSDDRVVIIW 101
>POF11_SCHPO (Q09855) F-box/WD-repeat protein pof11| Length = 506 Score = 65.5 bits (158), Expect = 9e-11 Identities = 40/141 (28%), Positives = 72/141 (51%), Gaps = 3/141 (2%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARM---TGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGI 365 S S D T +W + +A M GH VN V +S + +AS D++++ W+ Sbjct: 318 SSSRDHTARVWRLDATSPAEACMHVLRGHLASVNSVQYSSKTGLIVTASSDRTLRTWDIT 377 Query: 364 TGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAV 185 TG + H + ++ + ++SGS D T+++++ + KL + L GH D + V Sbjct: 378 TGHCIRIIHAHQRGIACAQYNG--KFIVSGSSDLTIRIFEASSGKLLRMLQGHEDLIRTV 435 Query: 184 DWSPDGEKVVSGGKDRALKLW 122 + + EK+VSGG D +++W Sbjct: 436 RF--NDEKIVSGGYDGTVRIW 454 Score = 54.3 bits (129), Expect = 2e-07 Identities = 36/142 (25%), Positives = 70/142 (49%), Gaps = 4/142 (2%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWN----G 368 SGS D T+ +W+ +++P GH V V S + ++ S+S D + ++W Sbjct: 278 SGSSDSTIIIWDWQ-NRRPLKVYFGHTDNVLGVVVSEN--YIISSSRDHTARVWRLDATS 334 Query: 367 ITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYA 188 + RGH+A V + +S+ + L+++ S D TL+ WDI + + H + Sbjct: 335 PAEACMHVLRGHLASVNSVQYSSKTGLIVTASSDRTLRTWDITTGHCIRIIHAHQRGIAC 394 Query: 187 VDWSPDGEKVVSGGKDRALKLW 122 + +G+ +VSG D ++++ Sbjct: 395 AQY--NGKFIVSGSSDLTIRIF 414 Score = 52.0 bits (123), Expect = 1e-06 Identities = 25/74 (33%), Positives = 41/74 (55%) Frame = -2 Query: 343 FRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGE 164 FR + VY + + D +++SGSKD T+ VWD+ +R + L GH+ V +D+ Sbjct: 217 FRATLDSVYCVQY--DDEIMVSGSKDRTVSVWDVNSRFILYKLYGHSGSVLCLDFCRRRN 274 Query: 163 KVVSGGKDRALKLW 122 +VSG D + +W Sbjct: 275 LLVSGSSDSTIIIW 288 Score = 51.6 bits (122), Expect = 1e-06 Identities = 29/101 (28%), Positives = 51/101 (50%) Frame = -2 Query: 424 DGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD 245 D + + S S D++V +W+ + + GH V + + LL+SGS DST+ +WD Sbjct: 230 DDEIMVSGSKDRTVSVWDVNSRFILYKLYGHSGSVLCLDFCRRRNLLVSGSSDSTIIIWD 289 Query: 244 IRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 + R+ + GH D V V S + ++S +D ++W Sbjct: 290 WQNRRPLKVYFGHTDNVLGVVVSEN--YIISSSRDHTARVW 328 Score = 50.8 bits (120), Expect = 2e-06 Identities = 38/142 (26%), Positives = 65/142 (45%), Gaps = 4/142 (2%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SGS D T+ +W+ S+ ++ GH V + F L S S D ++ +W+ + Sbjct: 236 SGSKDRTVSVWDVN-SRFILYKLYGHSGSVLCLDFCRRRNLLVSGSSDSTIIIWDWQNRR 294 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQD----LPGHADEVYA 188 + + GH +V + S ++S S+D T +VW + A + L GH V + Sbjct: 295 PLKVYFGHTDNVLGVVVS--ENYIISSSRDHTARVWRLDATSPAEACMHVLRGHLASVNS 352 Query: 187 VDWSPDGEKVVSGGKDRALKLW 122 V +S +V+ DR L+ W Sbjct: 353 VQYSSKTGLIVTASSDRTLRTW 374 Score = 35.4 bits (80), Expect = 0.10 Identities = 24/98 (24%), Positives = 51/98 (52%), Gaps = 1/98 (1%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITG- 359 SGS D T+ ++E + K + + GH+ ++ V F+ + + S +D +V++WN TG Sbjct: 404 SGSSDLTIRIFEASSGKLLRM-LQGHEDLIRTVRFNDEK--IVSGGYDGTVRIWNFNTGE 460 Query: 358 KFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWD 245 + + V+ + + D R +++ + S + VW+ Sbjct: 461 QHCVLHNSRNSRVFGLQF--DHRRIIACTHSSEILVWN 496
>SCON2_NEUCR (Q01277) Sulfur controller 2 (SCON2)| Length = 650 Score = 65.5 bits (158), Expect = 9e-11 Identities = 44/138 (31%), Positives = 67/138 (48%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 +GS D T+ +W + + + GH + + F D L S S D ++K+WN TG+ Sbjct: 309 TGSYDTTIKIWNIETEECIRT-LVGHTAGIRALQF--DDSKLISGSLDHTIKVWNWHTGE 365 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWS 176 ++ F H V IS D LL SGS D T+K++D +++ L GH+D V + Sbjct: 366 CLSTFAAHTDSV--ISVHFDGHLLASGSSDKTVKIFDFNSKE-TYCLKGHSDWVNSTHVD 422 Query: 175 PDGEKVVSGGKDRALKLW 122 V S D +KLW Sbjct: 423 IKSRTVFSASDDTTIKLW 440 Score = 60.8 bits (146), Expect = 2e-09 Identities = 35/116 (30%), Positives = 59/116 (50%) Frame = -2 Query: 469 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 290 + GH+ V + D LA+ S+D ++K+WN T + + GH A + + + D Sbjct: 290 LKGHENGVTCLQL--DDNILATGSYDTTIKIWNIETEECIRTLVGHTAGIRALQF--DDS 345 Query: 289 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 L+SGS D T+KVW+ + H D V +V + DG + SG D+ +K++ Sbjct: 346 KLISGSLDHTIKVWNWHTGECLSTFAAHTDSVISVHF--DGHLLASGSSDKTVKIF 399 Score = 55.8 bits (133), Expect = 7e-08 Identities = 43/134 (32%), Positives = 67/134 (50%), Gaps = 5/134 (3%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SGS D T+ +W + + + H V V+F DG LAS S DK+VK+++ K Sbjct: 349 SGSLDHTIKVWN-WHTGECLSTFAAHTDSVISVHF--DGHLLASGSSDKTVKIFD-FNSK 404 Query: 355 FVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAV--- 185 +GH V SR + S S D+T+K+WD+ R++ + GH V V Sbjct: 405 ETYCLKGHSDWVNSTHVDIKSRTVFSASDDTTIKLWDLDTRQVIRTYEGHVGHVQQVLIL 464 Query: 184 --DWSPDGEKVVSG 149 ++ PD E+V++G Sbjct: 465 PPEYEPD-EEVLNG 477 Score = 47.8 bits (112), Expect = 2e-05 Identities = 25/98 (25%), Positives = 49/98 (50%) Frame = -2 Query: 418 QWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIR 239 ++ + D +++LW+ TG+ + GH+ V+ ++ D+ ++SG+ D +K W+ R Sbjct: 549 RYFMTGGLDSTMRLWDSATGRCLRTLFGHLEGVWSLA--GDTIRVISGANDGMVKTWEPR 606 Query: 238 ARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKL 125 + K GH V V S + SG +D ++L Sbjct: 607 SGKCDATYTGHCGPVTCVGLS--DSLMASGSEDGTIRL 642 Score = 41.2 bits (95), Expect = 0.002 Identities = 26/96 (27%), Positives = 47/96 (48%), Gaps = 5/96 (5%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SGS D T+ +++ + + + GH VN + + + SAS D ++KLW+ T + Sbjct: 389 SGSSDKTVKIFD--FNSKETYCLKGHSDWVNSTHVDIKSRTVFSASDDTTIKLWDLDTRQ 446 Query: 355 FVTAFRGHVADVYQI-----SWSADSRLLLSGSKDS 263 + + GHV V Q+ + D +L S+D+ Sbjct: 447 VIRTYEGHVGHVQQVLILPPEYEPDEEVLNGASQDN 482 Score = 38.5 bits (88), Expect = 0.012 Identities = 18/57 (31%), Positives = 33/57 (57%) Frame = -2 Query: 292 RLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 R ++G DST+++WD + + L GH + V+++ + D +V+SG D +K W Sbjct: 549 RYFMTGGLDSTMRLWDSATGRCLRTLFGHLEGVWSL--AGDTIRVISGANDGMVKTW 603
>GBB3_TOBAC (Q40507) Guanine nucleotide-binding protein beta subunit| Length = 375 Score = 65.1 bits (157), Expect = 1e-10 Identities = 43/147 (29%), Positives = 68/147 (46%), Gaps = 9/147 (6%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SGS D T LW+ ++ + + GH+ VN V F PDG + S D + +L++ TG Sbjct: 222 SGSCDTTARLWDNRVASRAQRTFYGHEGDVNTVKFFPDGNRFGTGSEDGTCRLFDIRTGH 281 Query: 355 FVTAF-----RGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPG----HA 203 + + G + V +++S RLL G + VWD K+ +L G H Sbjct: 282 QLQVYYQPHGDGDIPHVTSMAFSISGRLLFVGYSNGDCYVWDTLLAKVVLNLGGVQNSHE 341 Query: 202 DEVYAVDWSPDGEKVVSGGKDRALKLW 122 + + S DG + +G D LK+W Sbjct: 342 GRISCLGLSADGSALCTGSWDTNLKIW 368 Score = 65.1 bits (157), Expect = 1e-10 Identities = 44/129 (34%), Positives = 72/129 (55%), Gaps = 9/129 (6%) Frame = -2 Query: 481 PKARM-TGHQKVVNHVYFSPDGQW-LASASFDKSVKLWNGITGKFVTAF-----RGHVAD 323 P +RM +GH+ V+ + PD L ++S D++ LW+ TG + F GH AD Sbjct: 147 PVSRMLSGHKGYVSSCQYVPDEDTHLITSSGDQTCVLWDITTGLRTSVFGGEFQSGHTAD 206 Query: 322 VYQISWSADS-RLLLSGSKDSTLKVWDIR-ARKLKQDLPGHADEVYAVDWSPDGEKVVSG 149 V +S S+ + RL +SGS D+T ++WD R A + ++ GH +V V + PDG + +G Sbjct: 207 VQSVSISSSNPRLFVSGSCDTTARLWDNRVASRAQRTFYGHEGDVNTVKFFPDGNRFGTG 266 Query: 148 GKDRALKLW 122 +D +L+ Sbjct: 267 SEDGTCRLF 275 Score = 39.3 bits (90), Expect = 0.007 Identities = 27/124 (21%), Positives = 56/124 (45%), Gaps = 8/124 (6%) Frame = -2 Query: 469 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 290 + GH V + ++P+ + SAS D + +WN +T + A + A V ++S + Sbjct: 61 LQGHTGKVYSLDWTPEKNRIVSASQDGRLIVWNALTSQKTHAIKLPCAWVMTCAFSPSGQ 120 Query: 289 LLLSGSKDSTLKVWDIRA-------RKLKQDLPGHADEVYAVDWSPDGE-KVVSGGKDRA 134 + G DS ++++ + + + L GH V + + PD + +++ D+ Sbjct: 121 SVACGGLDSVCSIYNLNSPIDKDGNHPVSRMLSGHKGYVSSCQYVPDEDTHLITSSGDQT 180 Query: 133 LKLW 122 LW Sbjct: 181 CVLW 184
>WDR17_HUMAN (Q8IZU2) WD-repeat protein 17| Length = 1322 Score = 65.1 bits (157), Expect = 1e-10 Identities = 42/128 (32%), Positives = 62/128 (48%), Gaps = 3/128 (2%) Frame = -2 Query: 496 TISKQPKARMTGHQKVVNHVYFSPDGQW-LASASFDKSVKLWNGITGKFVTAFRGHVADV 320 T S QP +GH V HV +SP + L S S D +V++W+ + GH A V Sbjct: 553 TSSDQPLKVFSGHTAKVFHVKWSPLREGILCSGSDDGTVRIWDYTQDACINILNGHTAPV 612 Query: 319 YQISWSAD-SRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGE-KVVSGG 146 + W+ + LL+SGS D T+KVWD R + H +VY + P + S Sbjct: 613 RGLMWNTEIPYLLISGSWDYTIKVWDTREGTCVDTVYDHGADVYGLTCHPSRPFTMASCS 672 Query: 145 KDRALKLW 122 +D ++LW Sbjct: 673 RDSTVRLW 680 Score = 50.8 bits (120), Expect = 2e-06 Identities = 26/88 (29%), Positives = 41/88 (46%), Gaps = 1/88 (1%) Frame = -2 Query: 397 FDKSVKLWNGITGKFVTAFRGHVADVYQISWSADS-RLLLSGSKDSTLKVWDIRARKLKQ 221 +D K W+ + GHV ++ + D LL + S D T+KVWDI Sbjct: 377 YDMGAKKWDFLRDL------GHVETIFDCKFKPDDPNLLATASFDGTIKVWDINTLTAVY 430 Query: 220 DLPGHADEVYAVDWSPDGEKVVSGGKDR 137 PG+ +Y++ W+P G ++GG R Sbjct: 431 TSPGNEGVIYSLSWAPGGLNCIAGGTSR 458 Score = 46.2 bits (108), Expect = 6e-05 Identities = 31/127 (24%), Positives = 60/127 (47%), Gaps = 4/127 (3%) Frame = -2 Query: 508 LWEPTISKQPKARMTGHQKVVNHVYFSPDG-QWLASASFDKSVKLWNGITGKFVTAFRGH 332 L++ K R GH + + F PD LA+ASFD ++K+W+ T V G+ Sbjct: 376 LYDMGAKKWDFLRDLGHVETIFDCKFKPDDPNLLATASFDGTIKVWDINTLTAVYTSPGN 435 Query: 331 VADVYQISWSADS-RLLLSGSKDSTLKVWDIRARKLKQDLPGH-ADEVYAVDWS-PDGEK 161 +Y +SW+ + G+ + +W+++ K+ Q H + ++ + WS D ++ Sbjct: 436 EGVIYSLSWAPGGLNCIAGGTSRNGAFIWNVQKGKIIQRFNEHGTNGIFCIAWSHKDSKR 495 Query: 160 VVSGGKD 140 + + D Sbjct: 496 IATCSSD 502 Score = 45.8 bits (107), Expect = 7e-05 Identities = 30/102 (29%), Positives = 53/102 (51%), Gaps = 2/102 (1%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLA-SASFDKSVKLWNGITG 359 SGSDD T+ +W+ T + GH V + ++ + +L S S+D ++K+W+ G Sbjct: 584 SGSDDGTVRIWDYTQDACINI-LNGHTAPVRGLMWNTEIPYLLISGSWDYTIKVWDTREG 642 Query: 358 KFVTAFRGHVADVYQISWSADSRLLLSG-SKDSTLKVWDIRA 236 V H ADVY ++ ++ S+DST+++W + A Sbjct: 643 TCVDTVYDHGADVYGLTCHPSRPFTMASCSRDSTVRLWSLTA 684
>COPB2_RAT (O35142) Coatomer subunit beta' (Beta'-coat protein) (Beta'-COP)| (p102) Length = 904 Score = 65.1 bits (157), Expect = 1e-10 Identities = 38/141 (26%), Positives = 64/141 (45%), Gaps = 3/141 (2%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSP-DGQWLASASFDKSVKLWNGITG 359 + SDD + LW+ GH V + +P D ASAS D+++K+W + Sbjct: 115 TSSDDMLIKLWDWDKKWSCSQVFEGHTHYVMQIVINPKDNNQFASASLDRTIKVWQLGSS 174 Query: 358 KFVTAFRGHVADVYQISW--SADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAV 185 GH V I + D L+SG+ D +K+WD + + Q GHA V Sbjct: 175 SPNFTLEGHEKGVNCIDYYSGGDKPYLISGADDRLVKIWDYQNKTCVQTPEGHAQNVSCA 234 Query: 184 DWSPDGEKVVSGGKDRALKLW 122 + P+ +++G +D +++W Sbjct: 235 TFHPELPIIITGSEDGTVRIW 255 Score = 52.8 bits (125), Expect = 6e-07 Identities = 33/119 (27%), Positives = 60/119 (50%), Gaps = 2/119 (1%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHV--YFSPDGQWLASASFDKSVKLWNGIT 362 S S D T+ +W+ S P + GH+K VN + Y D +L S + D+ VK+W+ Sbjct: 159 SASLDRTIKVWQLG-SSSPNFTLEGHEKGVNCIDYYSGGDKPYLISGADDRLVKIWDYQN 217 Query: 361 GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAV 185 V GH +V ++ + ++++GS+D T+++W +L+ L + V+ V Sbjct: 218 KTCVQTPEGHAQNVSCATFHPELPIIITGSEDGTVRIWHSSTYRLESTLNYGMERVWCV 276 Score = 42.4 bits (98), Expect = 8e-04 Identities = 25/119 (21%), Positives = 50/119 (42%) Frame = -2 Query: 478 KARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSA 299 K ++T V V P W+ ++ ++ SV +WN T V F V + A Sbjct: 7 KRKLTAMSDRVKSVDLHPTEPWMLASLYNGSVCVWNHETQTLVKTFEVCDLPVRAAKFVA 66 Query: 298 DSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 +++G+ D ++V++ + H+D + + P +++ D +KLW Sbjct: 67 RKNWVVTGADDMQIRVFNYNTLERVHMFEAHSDYIRCIAVHPTQPFILTSSDDMLIKLW 125
>HIRA_CHICK (P79987) HIRA protein (TUP1-like enhancer of split protein 1)| (CHIRA) Length = 1018 Score = 65.1 bits (157), Expect = 1e-10 Identities = 46/168 (27%), Positives = 75/168 (44%), Gaps = 31/168 (18%) Frame = -2 Query: 532 GSDDFTMFLWE--PTISKQ-------PK--ARMTGHQKVVNHVYFSPDGQWLASASFDKS 386 G D + +W P + ++ PK +M H VN V +S +G +LAS DK Sbjct: 34 GQDSGKVVIWNMAPVLKEEDEKNENIPKMLCQMDNHLACVNCVRWSNNGVYLASGGDDKL 93 Query: 385 VKLWN-----------GITGKFV-------TAFRGHVADVYQISWSADSRLLLSGSKDST 260 + +W G + K + R H DV ++WS L S S D+T Sbjct: 94 IMVWKRAAYIGPSTVFGSSSKLTNVEQWRCSILRSHSGDVMDVAWSPHDAWLASCSVDNT 153 Query: 259 LKVWD--IRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRALKLW 122 + +W+ ++ ++ L GH+ V + W P G+ + S DR+LK+W Sbjct: 154 VVIWNAAVKFPEILATLKGHSGLVKGLTWDPVGKYIASQADDRSLKVW 201 Score = 53.9 bits (128), Expect = 3e-07 Identities = 40/153 (26%), Positives = 61/153 (39%), Gaps = 25/153 (16%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVN-----------------HVYFSPDGQWLA 407 SG DD + +W+ P K+ N V +SP WLA Sbjct: 87 SGGDDKLIMVWKRAAYIGPSTVFGSSSKLTNVEQWRCSILRSHSGDVMDVAWSPHDAWLA 146 Query: 406 SASFDKSVKLWNGIT--GKFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRAR 233 S S D +V +WN + + +GH V ++W + + S + D +LKVW Sbjct: 147 SCSVDNTVVIWNAAVKFPEILATLKGHSGLVKGLTWDPVGKYIASQADDRSLKVWRTMDG 206 Query: 232 KLKQDLPGHADE------VYAVDWSPDGEKVVS 152 +L+ + DE V + SPDG +VS Sbjct: 207 QLETSITKPFDECGGTTHVLRLSGSPDGHYLVS 239 Score = 52.8 bits (125), Expect = 6e-07 Identities = 44/168 (26%), Positives = 75/168 (44%), Gaps = 29/168 (17%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPK--ARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGIT 362 S S D T+ +W + K P+ A + GH +V + + P G+++AS + D+S+K+W + Sbjct: 147 SCSVDNTVVIWNAAV-KFPEILATLKGHSGLVKGLTWDPVGKYIASQADDRSLKVWRTMD 205 Query: 361 GKFVTAFR------GHVADVYQISWSADSRLLLS----GSKDSTLKVWDIRARKLKQDLP 212 G+ T+ G V ++S S D L+S + T ++ + K D Sbjct: 206 GQLETSITKPFDECGGTTHVLRLSGSPDGHYLVSAHAMNNSGPTAQIIERDGWKTNMDFV 265 Query: 211 GHADEVYAVDWSP--------DGEKVVS---------GGKDRALKLWM 119 GH V V ++P +G S G KDR+L +W+ Sbjct: 266 GHRKAVTVVKFNPKIFKKKQKNGSSTKSSCPYCCCAVGSKDRSLSVWL 313
>GBB2_TOBAC (P93398) Guanine nucleotide-binding protein beta subunit 2| Length = 377 Score = 65.1 bits (157), Expect = 1e-10 Identities = 44/129 (34%), Positives = 71/129 (55%), Gaps = 9/129 (6%) Frame = -2 Query: 481 PKARM-TGHQKVVNHVYFSPDGQW-LASASFDKSVKLWNGITGKFVTAF-----RGHVAD 323 P +RM +GH+ V+ + PD + ++S D++ LW+ TG + F GH AD Sbjct: 147 PVSRMLSGHKGYVSSCQYVPDEDTHVITSSGDQTCVLWDITTGLRTSVFGGEFQSGHTAD 206 Query: 322 VYQISWSADS-RLLLSGSKDSTLKVWDIR-ARKLKQDLPGHADEVYAVDWSPDGEKVVSG 149 V +S S+ + RL +SGS DST ++WD R A + ++ GH +V V + PDG + +G Sbjct: 207 VQSVSISSSNPRLFVSGSCDSTARLWDTRVASRAQRTFYGHEGDVNTVKFFPDGNRFGTG 266 Query: 148 GKDRALKLW 122 D +L+ Sbjct: 267 SDDGTCRLF 275 Score = 63.2 bits (152), Expect = 5e-10 Identities = 42/147 (28%), Positives = 67/147 (45%), Gaps = 9/147 (6%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 SGS D T LW+ ++ + + GH+ VN V F PDG + S D + +L++ TG Sbjct: 222 SGSCDSTARLWDTRVASRAQRTFYGHEGDVNTVKFFPDGNRFGTGSDDGTCRLFDIRTGH 281 Query: 355 FVTAF-----RGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDL----PGHA 203 + + G + V +++S RLL G + VWD K+ +L H Sbjct: 282 QLQVYYQPHGDGDIPHVTSMAFSISGRLLFVGYSNGDCYVWDTLLAKVVLNLGAVQNSHE 341 Query: 202 DEVYAVDWSPDGEKVVSGGKDRALKLW 122 + + S DG + +G D LK+W Sbjct: 342 GRISCLGLSADGSALCTGSWDTNLKIW 368 Score = 40.8 bits (94), Expect = 0.002 Identities = 19/73 (26%), Positives = 33/73 (45%) Frame = -2 Query: 340 RGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEK 161 +GH VY + W+ + ++S S+D L VW+ + + V +SP G+ Sbjct: 62 QGHTGKVYSLDWTPEKNRIVSASQDGRLIVWNALTSQKTHAIKLPCAWVMTCAFSPSGQS 121 Query: 160 VVSGGKDRALKLW 122 V GG D ++ Sbjct: 122 VACGGLDSVCSIF 134 Score = 40.0 bits (92), Expect = 0.004 Identities = 28/124 (22%), Positives = 56/124 (45%), Gaps = 8/124 (6%) Frame = -2 Query: 469 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 290 + GH V + ++P+ + SAS D + +WN +T + A + A V ++S + Sbjct: 61 LQGHTGKVYSLDWTPEKNRIVSASQDGRLIVWNALTSQKTHAIKLPCAWVMTCAFSPSGQ 120 Query: 289 LLLSGSKDSTLKVWDIRA-------RKLKQDLPGHADEVYAVDWSPDGE-KVVSGGKDRA 134 + G DS ++++ + + + L GH V + + PD + V++ D+ Sbjct: 121 SVACGGLDSVCSIFNLNSPIDKDGNHPVSRMLSGHKGYVSSCQYVPDEDTHVITSSGDQT 180 Query: 133 LKLW 122 LW Sbjct: 181 CVLW 184
>WDR48_MACFA (Q4R2Z6) WD-repeat protein 48| Length = 622 Score = 63.9 bits (154), Expect = 3e-10 Identities = 41/147 (27%), Positives = 69/147 (46%), Gaps = 9/147 (6%) Frame = -2 Query: 535 SGSDDFTMFLWEPTISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGK 356 S S D T+ +W T H+ V + ++ D + +ASA D+ + LW+ T Sbjct: 92 SASSDTTVKVWNAHKGFCMSTLRT-HKDYVKALAYAKDKELVASAGLDRQIFLWDVNTLT 150 Query: 355 FVTA---------FRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRARKLKQDLPGHA 203 +TA G+ +Y ++ + +++SGS + L+VWD R L GH Sbjct: 151 ALTASNNTVTTSSLSGNKDSIYSLAMNQLGTIIVSGSTEKVLRVWDPRTCAKLMKLKGHT 210 Query: 202 DEVYAVDWSPDGEKVVSGGKDRALKLW 122 D V A+ + DG + +SG D ++LW Sbjct: 211 DNVKALLLNRDGTQCLSGSSDGTIRLW 237 Score = 62.4 bits (150), Expect = 8e-10 Identities = 39/145 (26%), Positives = 66/145 (45%), Gaps = 11/145 (7%) Frame = -2 Query: 523 DFTMFLWEPTISKQPK--ARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFV 350 D + +W KQ A M H VN + +G+ L SAS D +VK+WN G + Sbjct: 51 DSIIRIWSVNQHKQDPYIASMEHHTDWVNDIVLCCNGKTLISASSDTTVKVWNAHKGFCM 110 Query: 349 TAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIRA---------RKLKQDLPGHADE 197 + R H V ++++ D L+ S D + +WD+ L G+ D Sbjct: 111 STLRTHKDYVKALAYAKDKELVASAGLDRQIFLWDVNTLTALTASNNTVTTSSLSGNKDS 170 Query: 196 VYAVDWSPDGEKVVSGGKDRALKLW 122 +Y++ + G +VSG ++ L++W Sbjct: 171 IYSLAMNQLGTIIVSGSTEKVLRVW 195 Score = 49.7 bits (117), Expect = 5e-06 Identities = 27/113 (23%), Positives = 57/113 (50%) Frame = -2 Query: 469 MTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITGKFVTAFRGHVADVYQISWSADSR 290 ++G++ + + + G + S S +K +++W+ T + +GH +V + + D Sbjct: 164 LSGNKDSIYSLAMNQLGTIIVSGSTEKVLRVWDPRTCAKLMKLKGHTDNVKALLLNRDGT 223 Query: 289 LLLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPDGEKVVSGGKDRAL 131 LSGS D T+++W + ++ H + V+A+ + V SGG+DR + Sbjct: 224 QCLSGSSDGTIRLWSLGQQRCIATYRVHDEGVWALQVNDAFTHVYSGGRDRKI 276 Score = 38.9 bits (89), Expect = 0.009 Identities = 26/100 (26%), Positives = 48/100 (48%), Gaps = 1/100 (1%) Frame = -2 Query: 535 SGSDDFTMFLWEP-TISKQPKARMTGHQKVVNHVYFSPDGQWLASASFDKSVKLWNGITG 359 SGS + + +W+P T +K K + GH V + + DG S S D +++LW+ Sbjct: 185 SGSTEKVLRVWDPRTCAKLMKLK--GHTDNVKALLLNRDGTQCLSGSSDGTIRLWSLGQQ 242 Query: 358 KFVTAFRGHVADVYQISWSADSRLLLSGSKDSTLKVWDIR 239 + + +R H V+ + + + SG +D + D+R Sbjct: 243 RCIATYRVHDEGVWALQVNDAFTHVYSGGRDRKIYCTDLR 282 Score = 30.4 bits (67), Expect = 3.3 Identities = 17/61 (27%), Positives = 29/61 (47%), Gaps = 6/61 (9%) Frame = -2 Query: 286 LLSGSKDSTLKVWDIRARKLKQDLPGHADEVYAVDWSPD------GEKVVSGGKDRALKL 125 L + +DS +++W + KQD P A + DW D G+ ++S D +K+ Sbjct: 45 LFTAGRDSIIRIWSVNQH--KQD-PYIASMEHHTDWVNDIVLCCNGKTLISASSDTTVKV 101 Query: 124 W 122 W Sbjct: 102 W 102 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 84,836,087 Number of Sequences: 219361 Number of extensions: 1832309 Number of successful extensions: 10434 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 5673 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 8318 length of database: 80,573,946 effective HSP length: 105 effective length of database: 57,541,041 effective search space used: 4200495993 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
