>PUR8_HAEIN (P44797) Adenylosuccinate lyase (EC 4.3.2.2) (Adenylosuccinase)|
           (ASL)
          Length = 456

 Score =  219 bits (557), Expect = 9e-57
 Identities = 106/166 (63%), Positives = 133/166 (80%)
 Frame = -1

Query: 743 AGEVGSSTMPHKINPINFENSEGNFSVSNGLLCTLSMKLPISRLQRDLTDSTVLRNLGVG 564
           AGE+GSSTMPHK+NPI+FENSEGN  ++N ++  L  KLPISR QRDLTDSTVLRNLGVG
Sbjct: 290 AGEIGSSTMPHKVNPIDFENSEGNLGLANAVMTHLGQKLPISRWQRDLTDSTVLRNLGVG 349

Query: 563 LGHSLLAYKATMQGIKKLEVNKVRLDEDLEQTWEVLAEPIQTVMRRYGIPEPYEKLKEMT 384
           LG+ L+AY +T +GI KLEVN+  L E+L Q WEVLAEPIQTVMRRYGI +PYEKLKE+T
Sbjct: 350 LGYCLIAYASTRKGISKLEVNQPHLLEELNQNWEVLAEPIQTVMRRYGIEKPYEKLKELT 409

Query: 383 RGQAVTKDSIRQFIEGLDLPEDARSSLLKLTPHSYTGEAENLAANI 246
           RG+ VT+ ++R+FI+ LD+P++ +  L KLTP +Y G A  L   +
Sbjct: 410 RGKRVTEQAMREFIDKLDIPQEEKLRLQKLTPATYIGAAVELVEKL 455

>PUR8_ECOLI (P0AB89) Adenylosuccinate lyase (EC 4.3.2.2) (Adenylosuccinase)|
           (ASL)
          Length = 456

 Score =  215 bits (548), Expect = 1e-55
 Identities = 101/159 (63%), Positives = 133/159 (83%)
 Frame = -1

Query: 743 AGEVGSSTMPHKINPINFENSEGNFSVSNGLLCTLSMKLPISRLQRDLTDSTVLRNLGVG 564
           AGE+GSSTMPHK+NPI+FENSEGN  +SN +L  L+ KLP+SR QRDLTDSTVLRNLGVG
Sbjct: 290 AGEIGSSTMPHKVNPIDFENSEGNLGLSNAVLQHLASKLPVSRWQRDLTDSTVLRNLGVG 349

Query: 563 LGHSLLAYKATMQGIKKLEVNKVRLDEDLEQTWEVLAEPIQTVMRRYGIPEPYEKLKEMT 384
           +G++L+AY++T++G+ KLEVN+  L ++L+  WEVLAEPIQTVMRRYGI +PYEKLKE+T
Sbjct: 350 IGYALIAYQSTLKGVSKLEVNRDHLLDELDHNWEVLAEPIQTVMRRYGIEKPYEKLKELT 409

Query: 383 RGQAVTKDSIRQFIEGLDLPEDARSSLLKLTPHSYTGEA 267
           RG+ V  + ++QFI+GL LPE+ ++ L  +TP +Y G A
Sbjct: 410 RGKRVDAEGMKQFIDGLALPEEEKARLKAMTPANYIGRA 448

>PUR8_ECOL6 (P0AB90) Adenylosuccinate lyase (EC 4.3.2.2) (Adenylosuccinase)|
           (ASL)
          Length = 456

 Score =  215 bits (548), Expect = 1e-55
 Identities = 101/159 (63%), Positives = 133/159 (83%)
 Frame = -1

Query: 743 AGEVGSSTMPHKINPINFENSEGNFSVSNGLLCTLSMKLPISRLQRDLTDSTVLRNLGVG 564
           AGE+GSSTMPHK+NPI+FENSEGN  +SN +L  L+ KLP+SR QRDLTDSTVLRNLGVG
Sbjct: 290 AGEIGSSTMPHKVNPIDFENSEGNLGLSNAVLQHLASKLPVSRWQRDLTDSTVLRNLGVG 349

Query: 563 LGHSLLAYKATMQGIKKLEVNKVRLDEDLEQTWEVLAEPIQTVMRRYGIPEPYEKLKEMT 384
           +G++L+AY++T++G+ KLEVN+  L ++L+  WEVLAEPIQTVMRRYGI +PYEKLKE+T
Sbjct: 350 IGYALIAYQSTLKGVSKLEVNRDHLLDELDHNWEVLAEPIQTVMRRYGIEKPYEKLKELT 409

Query: 383 RGQAVTKDSIRQFIEGLDLPEDARSSLLKLTPHSYTGEA 267
           RG+ V  + ++QFI+GL LPE+ ++ L  +TP +Y G A
Sbjct: 410 RGKRVDAEGMKQFIDGLALPEEEKARLKAMTPANYIGRA 448

>PUR8_BUCBP (Q89AM3) Adenylosuccinate lyase (EC 4.3.2.2) (Adenylosuccinase)|
           (ASL)
          Length = 460

 Score =  187 bits (474), Expect = 4e-47
 Identities = 92/174 (52%), Positives = 124/174 (71%)
 Frame = -1

Query: 746 KAGEVGSSTMPHKINPINFENSEGNFSVSNGLLCTLSMKLPISRLQRDLTDSTVLRNLGV 567
           K  E+GSS MPHKINPI+FENSEGN  +SN ++  L  KLPISR QRDL+DSTVLRN+G 
Sbjct: 287 KLDEIGSSVMPHKINPIDFENSEGNLGLSNAIISHLIEKLPISRWQRDLSDSTVLRNVGT 346

Query: 566 GLGHSLLAYKATMQGIKKLEVNKVRLDEDLEQTWEVLAEPIQTVMRRYGIPEPYEKLKEM 387
            + +S++AY + + G+KKL+VN  RL +DL   WE+LAEPIQTVMR+YGI + Y +LK +
Sbjct: 347 VIAYSIIAYDSIILGLKKLKVNTSRLLQDLNHHWEILAEPIQTVMRKYGINDTYNELKNI 406

Query: 386 TRGQAVTKDSIRQFIEGLDLPEDARSSLLKLTPHSYTGEAENLAANIWNVVDLK 225
           TRG+ VT D I +++  L +P + +  LL+LTP +Y G +  L     N  +LK
Sbjct: 407 TRGKRVTSDIILKYVNSLKIPRNEKEKLLQLTPENYLGLSSKLVKIFNNSSELK 460

>PUR8_BUCAI (P57351) Adenylosuccinate lyase (EC 4.3.2.2) (Adenylosuccinase)|
           (ASL)
          Length = 456

 Score =  185 bits (469), Expect = 1e-46
 Identities = 84/164 (51%), Positives = 121/164 (73%)
 Frame = -1

Query: 737 EVGSSTMPHKINPINFENSEGNFSVSNGLLCTLSMKLPISRLQRDLTDSTVLRNLGVGLG 558
           E+GSS MPHK+NPI+FENSEGN  +SN L+  +  KLPISR QRDL+DSTVLRN+GV + 
Sbjct: 292 EIGSSIMPHKVNPIDFENSEGNLGLSNALMNHMITKLPISRWQRDLSDSTVLRNIGVAIS 351

Query: 557 HSLLAYKATMQGIKKLEVNKVRLDEDLEQTWEVLAEPIQTVMRRYGIPEPYEKLKEMTRG 378
           ++++AY + + GI KLE+N+  L ++L++ W +L+EPIQT+MRRYGI   YEKLK++TRG
Sbjct: 352 YAIIAYNSVLSGINKLEINESELLKNLDKNWSILSEPIQTIMRRYGIKNAYEKLKKLTRG 411

Query: 377 QAVTKDSIRQFIEGLDLPEDARSSLLKLTPHSYTGEAENLAANI 246
           + + ++ I  FI  L++PE+ +  L  +TP +Y G A  +   I
Sbjct: 412 KEINRNVIHTFISSLNIPEEEKKRLKNMTPFNYIGAASQIINEI 455

>PUR8_BUCAP (Q8K9Q7) Adenylosuccinate lyase (EC 4.3.2.2) (Adenylosuccinase)|
           (ASL)
          Length = 456

 Score =  171 bits (432), Expect = 3e-42
 Identities = 84/164 (51%), Positives = 116/164 (70%)
 Frame = -1

Query: 737 EVGSSTMPHKINPINFENSEGNFSVSNGLLCTLSMKLPISRLQRDLTDSTVLRNLGVGLG 558
           E+GSS MPHKINPI+FENSEGN  +SN L+  +  KLPISR QRDL+DSTVLRN+GV   
Sbjct: 292 EIGSSIMPHKINPIDFENSEGNLGLSNALMNHMINKLPISRWQRDLSDSTVLRNIGVVFA 351

Query: 557 HSLLAYKATMQGIKKLEVNKVRLDEDLEQTWEVLAEPIQTVMRRYGIPEPYEKLKEMTRG 378
           +S++AY + + G  KL +N  +L ++L+  W VL+E IQTVMRRY I   YEKLK++TRG
Sbjct: 352 YSIIAYNSVLLGTNKLTINTSQLLKNLDNNWSVLSEAIQTVMRRYTIENAYEKLKKLTRG 411

Query: 377 QAVTKDSIRQFIEGLDLPEDARSSLLKLTPHSYTGEAENLAANI 246
           + + K  I +FI+ L++P+  +  L K++P +Y G A  +   I
Sbjct: 412 KKIEKVDIHKFIDKLNIPKIEKERLKKISPSNYIGAASQIIDEI 455

>PUR8_METJA (Q58339) Adenylosuccinate lyase (EC 4.3.2.2) (Adenylosuccinase)|
           (ASL)
          Length = 462

 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 39/112 (34%), Positives = 59/112 (52%), Gaps = 5/112 (4%)
 Frame = -1

Query: 737 EVGSSTMPHKINPINFENSEGNFSVSNGLLCTLSMKLPISRLQRDLTDST----VLRNLG 570
           + GSSTMPHK NPI FE   G   V   L       +P+   +RDLT+S+    +   + 
Sbjct: 284 QTGSSTMPHKRNPITFEQICGLSRVIKSLCIAEMDNIPLWE-ERDLTNSSAERCIFAEVC 342

Query: 569 VGLGHSLLAYKATMQGIKKLEVNKVRLDEDLEQT-WEVLAEPIQTVMRRYGI 417
           V   H L      ++G+KKL+VNK  ++ +LE T   ++AE I   + + G+
Sbjct: 343 VLTDHIL---TLAIKGVKKLKVNKENVERNLELTKGLIMAERIMIELAKRGM 391

>PUR8_PYRAB (Q9UZ99) Adenylosuccinate lyase (EC 4.3.2.2) (Adenylosuccinase)|
           (ASL)
          Length = 450

 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 54/189 (28%), Positives = 87/189 (46%), Gaps = 20/189 (10%)
 Frame = -1

Query: 737 EVGSSTMPHKINPINFENSEGNFSVSNGLLCTLSMKLPISRLQRDLTDSTVLRNL----G 570
           +VGSSTMPHK NPI  E   G   V    +    +  P+   +RDLT+S+V R +     
Sbjct: 270 QVGSSTMPHKRNPIRTEKVCGLARVLYSNVIPALLNNPLWH-ERDLTNSSVERVILPESF 328

Query: 569 VGLGHSLLAYKATMQGIKKLEVNKVR---LDEDLEQTWEVLAEPIQTVMRRYGI--PEPY 405
           V L   L   K  ++G++    N  R   L ++L     ++AEP+   +   G+   E +
Sbjct: 329 VLLDEMLKVMKKVLKGLEFFPENIKRNLYLTKNL-----IMAEPLMLKLAEKGMGRQEAH 383

Query: 404 EKLKEMTRGQAVTKDSIRQFIEGLDLPEDAR-----------SSLLKLTPHSYTGEAENL 258
           E ++++         +++ F EG DL E  R           + L  L P +Y G+A  +
Sbjct: 384 ELVRQL---------AMKAFKEGRDLLEVVRKNEEAMKYLTENDLEGLKPENYIGKAREI 434

Query: 257 AANIWNVVD 231
             N+ N V+
Sbjct: 435 VENVVNYVE 443

>PUR8_PYRHO (O58582) Adenylosuccinate lyase (EC 4.3.2.2) (Adenylosuccinase)|
           (ASL)
          Length = 450

 Score = 47.0 bits (110), Expect = 6e-05
 Identities = 49/187 (26%), Positives = 84/187 (44%), Gaps = 18/187 (9%)
 Frame = -1

Query: 737 EVGSSTMPHKINPINFENSEGNFSVSNGLLCTLSMKLPISRLQRDLTDSTVLRNLGVGLG 558
           +VGSSTMPHK NPI  E   G   V    +    +  P+   +RDLT+S+V R   V L 
Sbjct: 270 QVGSSTMPHKRNPIRTEKVCGLARVLYSNVIPALLNNPLWH-ERDLTNSSVER---VILP 325

Query: 557 HSLLAYKATMQGIKKLEVNKVRLDEDLEQTWE-----VLAEPIQTVMRRYGI--PEPYEK 399
            S +     ++ +KK+        E++ +        ++AEP+   +   G+   E +E 
Sbjct: 326 ESFVLLDEMLKTMKKVLTGLEFFPENIRRNLYLTKNLIMAEPLMLKLAEKGMGRQEAHEV 385

Query: 398 LKEMTRGQAVTKDSIRQFIEGLDLPEDARSS-----------LLKLTPHSYTGEAENLAA 252
           ++++         +++ F E  DL E A+ S           L +L P +Y G+A  +  
Sbjct: 386 VRQL---------AMKAFRENRDLLEVAKESREITKYLTERDLEELKPENYIGKAREIVK 436

Query: 251 NIWNVVD 231
            +   V+
Sbjct: 437 KVIEYVE 443

>PUR8_BACSU (P12047) Adenylosuccinate lyase (EC 4.3.2.2) (Adenylosuccinase)|
           (ASL) (Glutamyl-tRNA synthetase regulatory factor)
          Length = 431

 Score = 40.4 bits (93), Expect = 0.006
 Identities = 28/95 (29%), Positives = 47/95 (49%), Gaps = 4/95 (4%)
 Frame = -1

Query: 740 GEVGSSTMPHKINPINFENSEGNFSVSNGLLCTLSMKLPISRLQRDLTDST----VLRNL 573
           G+ GSS MPHK NPI  EN  G   V  G + T    +P+   +RD++ S+    +L + 
Sbjct: 258 GQKGSSAMPHKRNPIGSENMTGMARVIRGYMMTAYENVPLWH-ERDISHSSAERIILPDA 316

Query: 572 GVGLGHSLLAYKATMQGIKKLEVNKVRLDEDLEQT 468
            + L + L  +      +K L V    +  ++++T
Sbjct: 317 TIALNYMLNRFSNI---VKNLTVFPENMKRNMDRT 348

>PUR8_ARCFU (O28041) Adenylosuccinate lyase (EC 4.3.2.2) (Adenylosuccinase)|
           (ASL)
          Length = 444

 Score = 38.5 bits (88), Expect = 0.022
 Identities = 37/124 (29%), Positives = 61/124 (49%), Gaps = 5/124 (4%)
 Frame = -1

Query: 746 KAGEVGSSTMPHKINPINFENSEGNFSVSNGLLCTLSMKLPISRLQRDLTDSTVLRNLGV 567
           +A +VGSSTMPHK NPI+ EN  G   V  G +     +  I   +RDLT+S+  R   V
Sbjct: 263 EAKQVGSSTMPHKRNPIDCENVCGLARVVRGFV-EPQHQSAILWEERDLTNSSAERITLV 321

Query: 566 G---LGHSLLAYKATMQGIKKLEVNKVRLDEDLEQTWEVLAEPIQTVMRRYGI--PEPYE 402
               L   +L     +     L +  +R + ++++    L+E +   M + G+   E +E
Sbjct: 322 ESTVLADHILTKMIKVVSSVSLNLENIRRNLEMQRGLN-LSEAVMIEMTKRGVGRQEAHE 380

Query: 401 KLKE 390
            L++
Sbjct: 381 ILRQ 384

>PCAB_PSEPU (P32427) 3-carboxy-cis,cis-muconate cycloisomerase (EC 5.5.1.2)|
           (3-carboxymuconate lactonizing enzyme) (CMLE)
          Length = 407

 Score = 37.0 bits (84), Expect = 0.065
 Identities = 36/116 (31%), Positives = 55/116 (47%), Gaps = 5/116 (4%)
 Frame = -1

Query: 740 GEVGSSTMPHKINPINFENSEGNFSVSNGLLCTLSMKLPISRLQRDL----TDSTVLRNL 573
           G+ GSSTMPHK NP+      G  +   GL+ TL   +P    +R L     +   L ++
Sbjct: 272 GKGGSSTMPHKRNPVGAAVLIGAATRVPGLVSTLFAAMP-QEHERSLGLWHAEWETLPDI 330

Query: 572 GVGLGHSLLAYKATMQGIKKLEVNKVRLDEDLEQTWE-VLAEPIQTVMRRYGIPEP 408
              +  +L   +   +GI   EV+  R+  +L+ T   VLAE +  V+ R   P P
Sbjct: 331 CCLVSGALRQAQVIAEGI---EVDAARMRRNLDLTQGLVLAEAVSIVLARTPGPRP 383

>PUR8_STRMU (P72478) Adenylosuccinate lyase (EC 4.3.2.2) (Adenylosuccinase)|
           (ASL)
          Length = 432

 Score = 35.8 bits (81), Expect = 0.15
 Identities = 21/54 (38%), Positives = 29/54 (53%)
 Frame = -1

Query: 740 GEVGSSTMPHKINPINFENSEGNFSVSNGLLCTLSMKLPISRLQRDLTDSTVLR 579
           G+ GSS MPHK NPI  EN  G   V  G + T    + +   +RD++ S+  R
Sbjct: 258 GQKGSSAMPHKRNPIGSENMTGLARVIRGHMVTAYENVSLWH-ERDISHSSAER 310

>ARLY_METJA (Q58201) Argininosuccinate lyase (EC 4.3.2.1) (Arginosuccinase)|
           (ASAL)
          Length = 484

 Score = 35.8 bits (81), Expect = 0.15
 Identities = 30/107 (28%), Positives = 49/107 (45%), Gaps = 2/107 (1%)
 Frame = -1

Query: 728 SSTMPHKINPINFENSEGNFSVSNGLLCTLS--MKLPISRLQRDLTDSTVLRNLGVGLGH 555
           SS MP K NP   E +    S  NG L T    +K   +   RDL +  +  +L   +  
Sbjct: 277 SSIMPQKKNPDVAEIARAKLSKLNGNLVTALTILKALPNTYNRDLQE--ISPHLWDSVYT 334

Query: 554 SLLAYKATMQGIKKLEVNKVRLDEDLEQTWEVLAEPIQTVMRRYGIP 414
           ++   K     +K +++NK R++E  +  +    E   T++R  GIP
Sbjct: 335 TIDTIKMVHGMLKTIKINKERMEELAKANYSTATELADTLVRETGIP 381

>PUR8_METTH (O27580) Adenylosuccinate lyase (EC 4.3.2.2) (Adenylosuccinase)|
           (ASL)
          Length = 449

 Score = 35.4 bits (80), Expect = 0.19
 Identities = 21/50 (42%), Positives = 28/50 (56%)
 Frame = -1

Query: 737 EVGSSTMPHKINPINFENSEGNFSVSNGLLCTLSMKLPISRLQRDLTDST 588
           +VGSSTMPHK+NPI  E   G   V    +       P+   +RDLT+S+
Sbjct: 272 QVGSSTMPHKMNPITAERICGIARVIRSYVVAALENNPLWH-ERDLTNSS 320

>PUR8_DEIRA (Q9RSE6) Adenylosuccinate lyase (EC 4.3.2.2) (Adenylosuccinase)|
           (ASL)
          Length = 435

 Score = 35.4 bits (80), Expect = 0.19
 Identities = 21/54 (38%), Positives = 30/54 (55%)
 Frame = -1

Query: 740 GEVGSSTMPHKINPINFENSEGNFSVSNGLLCTLSMKLPISRLQRDLTDSTVLR 579
           G+ GSS+MPHK NPI  EN  G   +  G L T    + +   +RD++ S+  R
Sbjct: 264 GQTGSSSMPHKKNPILTENVTGFARLLRGFLATGLENVALWH-ERDISHSSAER 316

>PUR8_THEMA (Q9X0I0) Adenylosuccinate lyase (EC 4.3.2.2) (Adenylosuccinase)|
           (ASL)
          Length = 431

 Score = 34.3 bits (77), Expect = 0.42
 Identities = 41/159 (25%), Positives = 74/159 (46%), Gaps = 9/159 (5%)
 Frame = -1

Query: 746 KAGEVGSSTMPHKINPINFENSEGNFSVSNGLLCTLSMKLPISRL--QRDLTDSTVLRNL 573
           + G+ GSS MPHK NPI  E   G   +S  +   +   L    L  +RD++ S+V R +
Sbjct: 256 RKGQRGSSAMPHKKNPITCERLTG---LSRMMRAYVDPSLENIALWHERDISHSSVERYV 312

Query: 572 GVGLGHSLLAYKATMQG-IKKLEVNKVRLDEDLEQT------WEVLAEPIQTVMRRYGIP 414
                 +L     T    ++ ++VN+ R+ ++++ T        VL + I+  + R    
Sbjct: 313 FPDATQTLYYMIVTATNVVRNMKVNEERMKKNIDLTKGLVFSQRVLLKLIEKGLTR---K 369

Query: 413 EPYEKLKEMTRGQAVTKDSIRQFIEGLDLPEDARSSLLK 297
           E Y+ ++   R    T +S + F+E L   E+ +  + K
Sbjct: 370 EAYDIVQ---RNALKTWNSEKHFLEYLLEDEEVKKLVTK 405

>SOMA_PROAN (O73848) Somatotropin precursor (Growth hormone)|
          Length = 206

 Score = 33.9 bits (76), Expect = 0.55
 Identities = 22/80 (27%), Positives = 37/80 (46%)
 Frame = -1

Query: 518 KKLEVNKVRLDEDLEQTWEVLAEPIQTVMRRYGIPEPYEKLKEMTRGQAVTKDSIRQFIE 339
           +K +++ +R    L Q W     P+Q + R +G P+ Y+KL ++ +G  V    +     
Sbjct: 91  QKSDMDLLRFSLSLIQAW---ISPLQILGRPFGSPDAYDKLLDLEKGLQVLMREL----- 142

Query: 338 GLDLPEDARSSLLKLTPHSY 279
                ED  S  L L  H+Y
Sbjct: 143 -----EDGSSRGLSLLKHTY 157

>PUR8_HELPJ (Q9ZKA2) Adenylosuccinate lyase (EC 4.3.2.2) (Adenylosuccinase)|
           (ASL)
          Length = 440

 Score = 33.9 bits (76), Expect = 0.55
 Identities = 21/55 (38%), Positives = 29/55 (52%)
 Frame = -1

Query: 743 AGEVGSSTMPHKINPINFENSEGNFSVSNGLLCTLSMKLPISRLQRDLTDSTVLR 579
           AG+ GSS MPHK NPI  EN  G   V       +   + +   +RD++ S+V R
Sbjct: 257 AGQKGSSAMPHKRNPILSENITGLCRVIRSFTTPMLENVALWH-ERDMSHSSVER 310

>ARLY_CANAL (P43061) Argininosuccinate lyase (EC 4.3.2.1) (Arginosuccinase)|
           (ASAL)
          Length = 468

 Score = 32.7 bits (73), Expect = 1.2
 Identities = 34/118 (28%), Positives = 54/118 (45%), Gaps = 5/118 (4%)
 Frame = -1

Query: 752 IAKAGEVGSSTMPHKINPINFENSEGN----FSVSNGLLCTLSMKLPISRLQRDL-TDST 588
           +A A   GSS MP K NP + E   G     F   +G L  +S+K   S   +D+  D  
Sbjct: 280 LADAYSTGSSLMPQKKNPDSLELLRGKSGRVFGQLSGFL--MSIKSIPSTYNKDMQEDKE 337

Query: 587 VLRNLGVGLGHSLLAYKATMQGIKKLEVNKVRLDEDLEQTWEVLAEPIQTVMRRYGIP 414
            L +    + HS+L        I  L ++K  +++ L  T ++LA  +   + R G+P
Sbjct: 338 PLFDALTTVEHSILIATGV---ISTLSIDKQNMEKAL--TMDMLATDLADYLVRKGVP 390

>PUR8_AQUAE (O66856) Adenylosuccinate lyase (EC 4.3.2.2) (Adenylosuccinase)|
           (ASL)
          Length = 437

 Score = 32.7 bits (73), Expect = 1.2
 Identities = 36/119 (30%), Positives = 61/119 (51%), Gaps = 7/119 (5%)
 Frame = -1

Query: 740 GEVGSSTMPHKINPINFENSEGNFSV--SNGLLCTLSMKLPISRLQRDLTDSTVLRNLGV 567
           G+ GSS MPHK NPI+ E   G   V  +N +    +M+  +   +RD++ S+V R   V
Sbjct: 261 GQRGSSAMPHKKNPIHSERICGLARVIRANSI---PAMEDVVLWHERDISHSSVER---V 314

Query: 566 GLGHSLLAYKATM----QGIKKLEVNKVRLDEDLEQTWEVLA-EPIQTVMRRYGIPEPY 405
            L  S +A    +    + +K L VNK R+ +++E +  + A   I  ++ + G+   Y
Sbjct: 315 ILPDSFIALDYILNLFYEILKGLVVNKERMRKNMELSKGLYASSKILVLLTQKGLSRDY 373

>PUR8_HELPY (P56468) Adenylosuccinate lyase (EC 4.3.2.2) (Adenylosuccinase)|
           (ASL)
          Length = 440

 Score = 32.3 bits (72), Expect = 1.6
 Identities = 20/54 (37%), Positives = 28/54 (51%)
 Frame = -1

Query: 740 GEVGSSTMPHKINPINFENSEGNFSVSNGLLCTLSMKLPISRLQRDLTDSTVLR 579
           G+ GSS MPHK NPI  EN  G   V       +   + +   +RD++ S+V R
Sbjct: 258 GQKGSSAMPHKRNPILSENITGLCRVIRSFTTPMLENVALWH-ERDMSHSSVER 310

>AROB_THEVO (Q978S6) 3-dehydroquinate synthase (EC 4.2.3.4)|
          Length = 360

 Score = 32.0 bits (71), Expect = 2.1
 Identities = 30/107 (28%), Positives = 50/107 (46%), Gaps = 8/107 (7%)
 Frame = -1

Query: 674 NFSVSNGLLCTLSMKLPISRLQRDLTDSTVLRNLGVGLGHSLL-----AYKATMQGIKKL 510
           NF      +  LS+K+    + RD  D T +R++ + LGH++      A K ++   K +
Sbjct: 205 NFDACATNIIKLSVKIKSEIVNRDFYDRTGIRSV-LNLGHTIAHGIEGATKGSISHGKAV 263

Query: 509 EVN---KVRLDEDLEQTWEVLAEPIQTVMRRYGIPEPYEKLKEMTRG 378
                 +  + E    T   + E I+ +M+RYGI E    LKE+  G
Sbjct: 264 ATGMLVEAHIGEKYGNTNHEVIEAIRDLMKRYGIEE--LNLKEIGPG 308

>MAVS_MOUSE (Q8VCF0) Mitochondrial antiviral signaling protein (Interferon-beta|
           promoter stimulator protein 1) (IPS-1) (Virus-induced
           signaling adapter) (CARD adapter inducing
           interferon-beta) (Cardif)
          Length = 503

 Score = 31.2 bits (69), Expect = 3.6
 Identities = 31/126 (24%), Positives = 48/126 (38%), Gaps = 5/126 (3%)
 Frame = -1

Query: 644 TLSMKLPISRLQRDLTDSTVLRNLGVGLGHSLLAYKATM-----QGIKKLEVNKVRLDED 480
           T+S KLP+S        STVL N       S   Y  T+       + K   N +  + +
Sbjct: 298 TMSSKLPLSSKSTAAMTSTVLTNTAPSKLPSNSVYAGTVPSRVPASVAKAPANTIPPERN 357

Query: 479 LEQTWEVLAEPIQTVMRRYGIPEPYEKLKEMTRGQAVTKDSIRQFIEGLDLPEDARSSLL 300
            +Q  E    P   V        P   ++ +  G  ++K  +   +  LD P  A S  L
Sbjct: 358 SKQAKETPEGPATKVTTGGNQTGPNSSIRSLHSGPEMSKPGV--LVSQLDEPFSACSVDL 415

Query: 299 KLTPHS 282
            ++P S
Sbjct: 416 AISPSS 421

>Y5100_ANASP (Q8YM40) Hypothetical UPF0192 protein all5100 precursor|
          Length = 1906

 Score = 31.2 bits (69), Expect = 3.6
 Identities = 18/58 (31%), Positives = 32/58 (55%)
 Frame = -1

Query: 644  TLSMKLPISRLQRDLTDSTVLRNLGVGLGHSLLAYKATMQGIKKLEVNKVRLDEDLEQ 471
            +L + +P+++L R   D T L+  G G  H L+AY   +QG +    N +R+  ++ Q
Sbjct: 1708 SLQLSVPMNQLPRGRHDLT-LQKSGNGTLHYLVAYNYRLQGNQPGRFNGLRITREISQ 1764

>SYT_NANEQ (Q74MP3) Threonyl-tRNA synthetase (EC 6.1.1.3) (Threonine--tRNA|
           ligase) (ThrRS)
          Length = 633

 Score = 31.2 bits (69), Expect = 3.6
 Identities = 33/128 (25%), Positives = 54/128 (42%), Gaps = 3/128 (2%)
 Frame = -1

Query: 560 GHSLLAYKATMQG--IKKLEVNKVRLDEDLEQTWEVLAEPIQTVMRRYGIPEPYEKLK-E 390
           GH L     T++   +KK E NKV L  D E+ + ++ +  + +++ Y   E  EKL  E
Sbjct: 127 GHPLAELSRTIKPKKVKKEEGNKVYLIYDGEKEYIIVGKKDKILVKDYKEIENKEKLHFE 186

Query: 389 MTRGQAVTKDSIRQFIEGLDLPEDARSSLLKLTPHSYTGEAENLAANIWNVVDLKSGFKI 210
           + +             +G++LP        K+       E E +  N  N V  K GF+ 
Sbjct: 187 LPK-------------DGIELPIPINQDFEKMVLKEVFSEGEEIEKNPLNDVAKKFGFEW 233

Query: 209 K*ASILAH 186
           +  S   H
Sbjct: 234 EPLSDYGH 241

>PUR8_SYNY3 (P74384) Adenylosuccinate lyase (EC 4.3.2.2) (Adenylosuccinase)|
           (ASL)
          Length = 431

 Score = 30.8 bits (68), Expect = 4.7
 Identities = 19/54 (35%), Positives = 27/54 (50%)
 Frame = -1

Query: 740 GEVGSSTMPHKINPINFENSEGNFSVSNGLLCTLSMKLPISRLQRDLTDSTVLR 579
           G+ GSS MPHK NPI  E   G   +  G        + +   +RD++ S+V R
Sbjct: 258 GQKGSSAMPHKRNPIRSERLTGMARLVRGHAVAALENVALWH-ERDISHSSVER 310

>CHM4C_MOUSE (Q9D7F7) Charged multivesicular body protein 4c|
           (Chromatin-modifying protein 4c) (CHMP4c)
          Length = 232

 Score = 30.8 bits (68), Expect = 4.7
 Identities = 25/120 (20%), Positives = 57/120 (47%), Gaps = 1/120 (0%)
 Frame = -1

Query: 659 NGLLCTLSMKLPISRLQRDLTDSTVLRNLGVGLGHSLLAYKATMQGIKKLEVNKVR-LDE 483
           +G L T+  +     L+   T++ VLRN+G        A KA       +++NK+  L +
Sbjct: 83  DGTLSTIEFQR--EALENSHTNTEVLRNMG-------FAAKAMKAVHDNMDLNKIDDLMQ 133

Query: 482 DLEQTWEVLAEPIQTVMRRYGIPEPYEKLKEMTRGQAVTKDSIRQFIEGLDLPEDARSSL 303
           D+ +  ++  E  +   +R    + +++ + +   + + ++ + + +  L+LP    SSL
Sbjct: 134 DITEQQDIAQEISEAFSQRVQFADGFDEAELLAELEELEQEELNKKMTSLELPNVPSSSL 193

>UACA_HUMAN (Q9BZF9) Uveal autoantigen with coiled-coil domains and ankyrin|
            repeats protein
          Length = 1416

 Score = 30.4 bits (67), Expect = 6.1
 Identities = 37/152 (24%), Positives = 72/152 (47%), Gaps = 11/152 (7%)
 Frame = -1

Query: 635  MKLPISRLQRDLTDSTVLRNLGVGLGHSL------LAYKATMQGIKKLEVNKVR---LDE 483
            +K  I  LQ+DL D TVL      +  +L      L  +      K  EV  V+   ++E
Sbjct: 1033 LKKEIFTLQKDLRDKTVLIEKSHEMERALSRKTDELNKQLKDLSQKYTEVKNVKEKLVEE 1092

Query: 482  DLEQTWEVLAEPIQTVMRRYGIP-EPYEKLKEMTRGQAVTKDSIRQFIEGLD-LPEDARS 309
            + +QT E+LA  +Q ++++  +P E  E LK+   G   T +++++ ++ +    E  + 
Sbjct: 1093 NAKQTSEILA--VQNLLQKQHVPLEQVEALKKSLNG---TIENLKEELKSMQRCYEKEQQ 1147

Query: 308  SLLKLTPHSYTGEAENLAANIWNVVDLKSGFK 213
            ++ KL  H      +N +  +   + +K  F+
Sbjct: 1148 TVTKL--HQLLENQKNSSVPLAEHLQIKEAFE 1177

>HIS8_AQUAE (O67857) Histidinol-phosphate aminotransferase (EC 2.6.1.9)|
           (Imidazole acetol-phosphate transaminase)
          Length = 354

 Score = 30.4 bits (67), Expect = 6.1
 Identities = 30/105 (28%), Positives = 56/105 (53%), Gaps = 1/105 (0%)
 Frame = -1

Query: 596 DSTVLRNLG-VGLGHSLLAYKATMQGIKKLEVNKVRLDEDLEQTWEVLAEPIQTVMRRYG 420
           D+ VLR L  +G+  SL       +G    E+NKVRL  ++    +V+A+ + T  R + 
Sbjct: 199 DTVVLRTLSKIGMA-SLRVGILIGKGEIVSEINKVRLPFNVTYPSQVMAKVLLTEGREFL 257

Query: 419 IPEPYEKLKEMTRGQAVTKDSIRQFIEGLDLPEDARSSLLKLTPH 285
           +    EK++E+ + +    D +++ IEG+++     + LL  TP+
Sbjct: 258 M----EKIQEVVKERERMYDEMKK-IEGVEVFPSKANFLLFRTPY 297

>FUMC_PROMM (Q7V5R2) Fumarate hydratase class II (EC 4.2.1.2) (Fumarase C)|
          Length = 466

 Score = 30.0 bits (66), Expect = 8.0
 Identities = 26/95 (27%), Positives = 42/95 (44%), Gaps = 5/95 (5%)
 Frame = -1

Query: 737 EVGSSTMPHKINPINFENSEGNFSVSNGLLCTLSMKLPISRLQRDLTDSTVLRNLGVGLG 558
           E GSS MP K+NP   E          GL   ++M      LQ ++    +    G  L 
Sbjct: 317 EPGSSIMPGKVNPSQCEAMAMVCLQVIGLDSAVTMAGGSGHLQMNVYKPLI----GFNLL 372

Query: 557 HSL-----LAYKATMQGIKKLEVNKVRLDEDLEQT 468
           HS+        K  +  ++ +E N++++  DLEQ+
Sbjct: 373 HSIELLHDACRKYRLAMVQGIEPNRIKIQHDLEQS 407

>ASPH_BOVIN (Q28056) Aspartyl/asparaginyl beta-hydroxylase (EC 1.14.11.16)|
           (Aspartate beta-hydroxylase) (ASP beta-hydroxylase)
           (Peptide-aspartate beta-dioxygenase)
          Length = 754

 Score = 30.0 bits (66), Expect = 8.0
 Identities = 22/83 (26%), Positives = 42/83 (50%)
 Frame = -1

Query: 539 KATMQGIKKLEVNKVRLDEDLEQTWEVLAEPIQTVMRRYGIPEPYEKLKEMTRGQAVTKD 360
           KA +   +KL   + +++E +    E++ +  Q+   RYG  +  + L E  R   + + 
Sbjct: 338 KAELDAAEKLR-KRGKIEEAVNAFEELVRKYPQSPGARYGKAQCEDDLAEKRRSNEILRR 396

Query: 359 SIRQFIEGLDLPEDARSSLLKLT 291
           +I  + E   LP DA + L+KL+
Sbjct: 397 AIETYQEAASLP-DAPTDLVKLS 418

>ASPH_HUMAN (Q12797) Aspartyl/asparaginyl beta-hydroxylase (EC 1.14.11.16)|
           (Aspartate beta-hydroxylase) (ASP beta-hydroxylase)
           (Peptide-aspartate beta-dioxygenase)
          Length = 757

 Score = 30.0 bits (66), Expect = 8.0
 Identities = 23/83 (27%), Positives = 41/83 (49%)
 Frame = -1

Query: 539 KATMQGIKKLEVNKVRLDEDLEQTWEVLAEPIQTVMRRYGIPEPYEKLKEMTRGQAVTKD 360
           KA +   +KL   + +++E +    E++ +  Q+   RYG  +  + L E  R   V + 
Sbjct: 342 KAELDAAEKLR-KRGKIEEAVNAFKELVRKYPQSPRARYGKAQCEDDLAEKRRSNEVLRG 400

Query: 359 SIRQFIEGLDLPEDARSSLLKLT 291
           +I  + E   LP D  + LLKL+
Sbjct: 401 AIETYQEVASLP-DVPADLLKLS 422


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 109,569,570
Number of Sequences: 219361
Number of extensions: 2333004
Number of successful extensions: 5816
Number of sequences better than 10.0: 33
Number of HSP's better than 10.0 without gapping: 5667
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5814
length of database: 80,573,946
effective HSP length: 110
effective length of database: 56,444,236
effective search space used: 7902193040
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)