ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | rbags9l03 |
|---|---|
| Clone Library Name | barley_pub |
>HT1_ARATH (Q2MHE4) Serine/threonine-protein kinase HT1 (EC 2.7.11.1) (High| leaf temperature protein 1) Length = 390 Score = 133 bits (334), Expect = 5e-31 Identities = 67/140 (47%), Positives = 84/140 (60%) Frame = -2 Query: 572 GTYRWMAPEMIQHRPYNQKVDVYSFGIVLWELITGTLPFPNMTAVQAAFAVVNKGVRPAI 393 GTYRWMAPEMI+ +PY +KVDVYSFGIVLWEL T LPF MT VQAAFAV K RP + Sbjct: 248 GTYRWMAPEMIKEKPYTRKVDVYSFGIVLWELTTALLPFQGMTPVQAAFAVAEKNERPPL 307 Query: 392 PHDCLPALGEIMTRCWDANPDVRPPFTDVARMLERVEIEVLNNVRKARFRCCISQPMTLD 213 P C PAL ++ RCW NP RP F+++ +LE+ + C+ + + L Sbjct: 308 PASCQPALAHLIKRCWSENPSKRPDFSNIVAVLEKYDE-------------CVKEGLPLT 354 Query: 212 *GRQNSKEKKAIWREVKSHV 153 +K KKAI +K V Sbjct: 355 SHASLTKTKKAILDHLKGCV 374
>MLTK_MOUSE (Q9ESL4) Mitogen-activated protein kinase kinase kinase MLT (EC| 2.7.11.25) (MLK-like mitogen-activated protein triple kinase) (Leucine zipper-and sterile alpha motif kinase ZAK) (Sterile alpha motif- and leucine zipper-containing kinase AZK) ( Length = 802 Score = 92.4 bits (228), Expect = 1e-18 Identities = 45/120 (37%), Positives = 69/120 (57%), Gaps = 9/120 (7%) Frame = -2 Query: 572 GTYRWMAPEMIQHRPYNQKVDVYSFGIVLWELITGTLPFPNMTAVQAAFAVVNKGVRPAI 393 GT+ WMAPE+IQ P ++ D YS+G+VLWE++T +PF + +Q A+ VV K R I Sbjct: 168 GTFPWMAPEVIQSLPVSETCDTYSYGVVLWEMLTREVPFKGLEGLQVAWLVVEKNERLTI 227 Query: 392 PHDCLPALGEIMTRCWDANPDVRPPFTDVARMLERVEIEV---------LNNVRKARFRC 240 P C + E++ +CW+A+ RP F + +LE + + L+N KA +RC Sbjct: 228 PSSCPRSFAELLHQCWEADAKKRPSFKQIISILESMSNDTNLPDQCNSFLHN--KAEWRC 285
>MLTK_HUMAN (Q9NYL2) Mitogen-activated protein kinase kinase kinase MLT (EC| 2.7.11.25) (MLK-like mitogen-activated protein triple kinase) (Leucine zipper-and sterile alpha motif-containing kinase) (Sterile alpha motif- and leucine zipper-containing kinase Length = 800 Score = 92.4 bits (228), Expect = 1e-18 Identities = 45/120 (37%), Positives = 69/120 (57%), Gaps = 9/120 (7%) Frame = -2 Query: 572 GTYRWMAPEMIQHRPYNQKVDVYSFGIVLWELITGTLPFPNMTAVQAAFAVVNKGVRPAI 393 GT+ WMAPE+IQ P ++ D YS+G+VLWE++T +PF + +Q A+ VV K R I Sbjct: 168 GTFPWMAPEVIQSLPVSETCDTYSYGVVLWEMLTREVPFKGLEGLQVAWLVVEKNERLTI 227 Query: 392 PHDCLPALGEIMTRCWDANPDVRPPFTDVARMLERVEIEV---------LNNVRKARFRC 240 P C + E++ +CW+A+ RP F + +LE + + L+N KA +RC Sbjct: 228 PSSCPRSFAELLHQCWEADAKKRPSFKQIISILESMSNDTSLPDKCNSFLHN--KAEWRC 285
>KYK2_DICDI (P18161) Tyrosine-protein kinase 2 (EC 2.7.10.2) (Fragment)| Length = 410 Score = 90.9 bits (224), Expect = 3e-18 Identities = 44/135 (32%), Positives = 74/135 (54%), Gaps = 14/135 (10%) Frame = -2 Query: 647 INRSRLLTSEVARIEVKTEGMTPETGTY-------------RWMAPEMIQHRP-YNQKVD 510 + +L E+ I++ G++ E RW PE+ ++ Y++KVD Sbjct: 233 LTSQNILLDELGNIKISDFGLSAEKSREGSMTMTNGGICNPRWRPPELTKNLGHYSEKVD 292 Query: 509 VYSFGIVLWELITGTLPFPNMTAVQAAFAVVNKGVRPAIPHDCLPALGEIMTRCWDANPD 330 VY F +V+WE++TG +PF ++ Q + V G+RP IP C P L ++T+CW+A+P+ Sbjct: 293 VYCFSLVVWEILTGEIPFSDLDGSQRSAQVAYAGLRPPIPEYCDPELKLLLTQCWEADPN 352 Query: 329 VRPPFTDVARMLERV 285 RPPFT + L+ + Sbjct: 353 DRPPFTYIVNKLKEI 367
>M3K11_HUMAN (Q16584) Mitogen-activated protein kinase kinase kinase 11 (EC| 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline-rich kinase) Length = 847 Score = 89.7 bits (221), Expect = 7e-18 Identities = 48/125 (38%), Positives = 73/125 (58%), Gaps = 1/125 (0%) Frame = -2 Query: 617 VARIEVKTEGMTPETGTYRWMAPEMIQHRPYNQKVDVYSFGIVLWELITGTLPFPNMTAV 438 +AR KT M+ GTY WMAPE+I+ +++ DV+SFG++LWEL+TG +P+ + + Sbjct: 270 LAREWHKTTQMSA-AGTYAWMAPEVIKASTFSKGSDVWSFGVLLWELLTGEVPYRGIDCL 328 Query: 437 QAAFAV-VNKGVRPAIPHDCLPALGEIMTRCWDANPDVRPPFTDVARMLERVEIEVLNNV 261 A+ V VNK P IP C ++M CW +P RP F + + LE +E +VL + Sbjct: 329 AVAYGVAVNKLTLP-IPSTCPEPFAQLMADCWAQDPHRRPDFASILQQLEALEAQVLREM 387 Query: 260 RKARF 246 + F Sbjct: 388 PRDSF 392
>M3K9_HUMAN (P80192) Mitogen-activated protein kinase kinase kinase 9 (EC| 2.7.11.25) (Mixed lineage kinase 1) Length = 1104 Score = 87.0 bits (214), Expect = 4e-17 Identities = 39/111 (35%), Positives = 62/111 (55%) Frame = -2 Query: 572 GTYRWMAPEMIQHRPYNQKVDVYSFGIVLWELITGTLPFPNMTAVQAAFAVVNKGVRPAI 393 GTY WMAPE+I+ +++ DV+S+G++LWEL+TG +PF + + A+ V + I Sbjct: 311 GTYAWMAPEVIRASMFSKGSDVWSYGVLLWELLTGEVPFRGIDGLAVAYGVAMNKLALPI 370 Query: 392 PHDCLPALGEIMTRCWDANPDVRPPFTDVARMLERVEIEVLNNVRKARFRC 240 P C ++M CW+ +P RP FT++ L +E + K F C Sbjct: 371 PSTCPEPFAKLMEDCWNPDPHSRPSFTNILDQLTTIEESGFFEMPKDSFHC 421
>M3K12_HUMAN (Q12852) Mitogen-activated protein kinase kinase kinase 12 (EC| 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK) Length = 859 Score = 87.0 bits (214), Expect = 4e-17 Identities = 36/110 (32%), Positives = 66/110 (60%) Frame = -2 Query: 572 GTYRWMAPEMIQHRPYNQKVDVYSFGIVLWELITGTLPFPNMTAVQAAFAVVNKGVRPAI 393 GT WMAPE+I++ P ++KVD++SFG+VLWEL+TG +P+ ++ + + V + + + Sbjct: 272 GTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTGEIPYKDVDSSAIIWGVGSNSLHLPV 331 Query: 392 PHDCLPALGEIMTRCWDANPDVRPPFTDVARMLERVEIEVLNNVRKARFR 243 P C ++ +CW++ P RP F + L+ +VL+ ++ F+ Sbjct: 332 PSSCPDGFKILLRQCWNSKPRNRPSFRQILLHLDIASADVLSTPQETYFK 381
>M3K10_HUMAN (Q02779) Mitogen-activated protein kinase kinase kinase 10 (EC| 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST) Length = 954 Score = 87.0 bits (214), Expect = 4e-17 Identities = 43/116 (37%), Positives = 66/116 (56%) Frame = -2 Query: 617 VARIEVKTEGMTPETGTYRWMAPEMIQHRPYNQKVDVYSFGIVLWELITGTLPFPNMTAV 438 +AR KT M+ GTY WMAPE+I+ +++ DV+SFG++LWEL+TG +P+ + A+ Sbjct: 251 LAREWHKTTKMSA-AGTYAWMAPEVIRLSLFSKSSDVWSFGVLLWELLTGEVPYREIDAL 309 Query: 437 QAAFAVVNKGVRPAIPHDCLPALGEIMTRCWDANPDVRPPFTDVARMLERVEIEVL 270 A+ V + IP C ++ CWD +P RP F + + LE +E L Sbjct: 310 AVAYGVAMNKLTLPIPSTCPEPFARLLEECWDPDPHGRPDFGSILKRLEVIEQSAL 365
>M3K12_MOUSE (Q60700) Mitogen-activated protein kinase kinase kinase 12 (EC| 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK) Length = 888 Score = 87.0 bits (214), Expect = 4e-17 Identities = 36/110 (32%), Positives = 66/110 (60%) Frame = -2 Query: 572 GTYRWMAPEMIQHRPYNQKVDVYSFGIVLWELITGTLPFPNMTAVQAAFAVVNKGVRPAI 393 GT WMAPE+I++ P ++KVD++SFG+VLWEL+TG +P+ ++ + + V + + + Sbjct: 305 GTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTGEIPYKDVDSSAIIWGVGSNSLHLPV 364 Query: 392 PHDCLPALGEIMTRCWDANPDVRPPFTDVARMLERVEIEVLNNVRKARFR 243 P C ++ +CW++ P RP F + L+ +VL+ ++ F+ Sbjct: 365 PSSCPDGFKILLRQCWNSKPRNRPSFRQILLHLDIASADVLSTPQETYFK 414
>M3K12_RAT (Q63796) Mitogen-activated protein kinase kinase kinase 12 (EC| 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK) Length = 888 Score = 86.3 bits (212), Expect = 7e-17 Identities = 36/110 (32%), Positives = 65/110 (59%) Frame = -2 Query: 572 GTYRWMAPEMIQHRPYNQKVDVYSFGIVLWELITGTLPFPNMTAVQAAFAVVNKGVRPAI 393 GT WMAPE+I++ P ++KVD++SFG+VLWEL+TG +P+ ++ + + V + + + Sbjct: 305 GTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTGEIPYKDVDSSAIIWGVGSNSLHLPV 364 Query: 392 PHDCLPALGEIMTRCWDANPDVRPPFTDVARMLERVEIEVLNNVRKARFR 243 P C ++ +CW+ P RP F + L+ +VL+ ++ F+ Sbjct: 365 PSSCPDGFKILLRQCWNRKPRNRPSFRQILLHLDIASADVLSTPQETYFK 414
>M3KL4_HUMAN (Q5TCX8) Mitogen-activated protein kinase kinase kinase (EC| 2.7.11.25) (Mixed lineage kinase 4) Length = 1036 Score = 84.0 bits (206), Expect = 4e-16 Identities = 39/110 (35%), Positives = 64/110 (58%), Gaps = 1/110 (0%) Frame = -2 Query: 572 GTYRWMAPEMIQHRPYNQKVDVYSFGIVLWELITGTLPFPNMTAVQAAFAV-VNKGVRPA 396 GTY WMAPE+I+ +++ D++S+G++LWEL+TG +P+ + + A+ V VNK P Sbjct: 306 GTYAWMAPEVIKSSLFSKGSDIWSYGVLLWELLTGEVPYRGIDGLAVAYGVAVNKLTLP- 364 Query: 395 IPHDCLPALGEIMTRCWDANPDVRPPFTDVARMLERVEIEVLNNVRKARF 246 IP C ++M CW +P +RP F + L +E V+ + + F Sbjct: 365 IPSTCPEPFAKLMKECWQQDPHIRPSFALILEQLTAIEGAVMTEMPQESF 414
>M3KSL_DROME (Q95UN8) Mitogen-activated protein kinase kinase kinase (EC| 2.7.11.25) (Mixed lineage kinase) (dMLK) (Protein slipper) Length = 1161 Score = 83.6 bits (205), Expect = 5e-16 Identities = 40/111 (36%), Positives = 60/111 (54%) Frame = -2 Query: 617 VARIEVKTEGMTPETGTYRWMAPEMIQHRPYNQKVDVYSFGIVLWELITGTLPFPNMTAV 438 +AR T+ M+ GTY WM PE+I Y++ DV+S+G++LWELITG P+ + Sbjct: 293 LAREMYNTQRMSA-AGTYAWMPPEVISVSTYSKFSDVWSYGVLLWELITGETPYKGFDPL 351 Query: 437 QAAFAVVNKGVRPAIPHDCLPALGEIMTRCWDANPDVRPPFTDVARMLERV 285 A+ V + IP C G +M CW +P RP F ++ + LE + Sbjct: 352 SVAYGVAVNTLTLPIPKTCPETWGALMKSCWQTDPHKRPGFKEILKQLESI 402
>YR831_MIMIV (Q7T6Y2) Putative serine/threonine-protein kinase/receptor R831| precursor (EC 2.7.11.1) Length = 1624 Score = 82.0 bits (201), Expect = 1e-15 Identities = 41/107 (38%), Positives = 62/107 (57%) Frame = -2 Query: 614 ARIEVKTEGMTPETGTYRWMAPEMIQHRPYNQKVDVYSFGIVLWELITGTLPFPNMTAVQ 435 ARI+ MT GT W APE+I+ Y +K DV+SFG+V+WE++TG PF ++ Sbjct: 1509 ARIKEDNTTMT-RCGTPCWTAPEVIRGEKYCEKADVFSFGVVMWEVLTGKEPFAECNFMK 1567 Query: 434 AAFAVVNKGVRPAIPHDCLPALGEIMTRCWDANPDVRPPFTDVARML 294 + ++ +G RP IP DC +++ +CW A RP T+V + L Sbjct: 1568 VSLDIL-EGGRPIIPSDCPHEFAKLIKKCWHAKAHKRPTMTEVVQQL 1613 Score = 70.5 bits (171), Expect = 4e-12 Identities = 34/102 (33%), Positives = 56/102 (54%), Gaps = 6/102 (5%) Frame = -2 Query: 572 GTYRWMAPEMIQHRPYNQKV--DVYSFGIVLWELITGTLPFPNMTAVQAAFAVVNKGVRP 399 GT W+APE++ + DVYSFGI+LWEL+T P+ MT A +V+ G+RP Sbjct: 947 GTIHWIAPEILNDSTEVDYILADVYSFGIILWELLTREQPYKGMTPAAIAVSVIRDGMRP 1006 Query: 398 AIPHDCLPALG----EIMTRCWDANPDVRPPFTDVARMLERV 285 I + + A +++ +CW ++ +RP F ++ L + Sbjct: 1007 PISDEAVTAHSIEYIDLIKQCWHSDTIIRPTFLEIMTRLSNI 1048
>M3K13_HUMAN (O43283) Mitogen-activated protein kinase kinase kinase 13 (EC| 2.7.11.25) (Mixed lineage kinase) (MLK) (Leucine zipper-bearing kinase) Length = 966 Score = 81.6 bits (200), Expect = 2e-15 Identities = 36/110 (32%), Positives = 62/110 (56%) Frame = -2 Query: 572 GTYRWMAPEMIQHRPYNQKVDVYSFGIVLWELITGTLPFPNMTAVQAAFAVVNKGVRPAI 393 GT WMAPE+I++ P ++KVD++SFG+VLWEL+TG +P+ ++ + + V + + + Sbjct: 315 GTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTGEIPYKDVDSSAIIWGVGSNSLHLPV 374 Query: 392 PHDCLPALGEIMTRCWDANPDVRPPFTDVARMLERVEIEVLNNVRKARFR 243 P C +M + W + P RP F L+ +VL ++ F+ Sbjct: 375 PSTCPDGFKILMKQTWQSKPRNRPSFRQTLMHLDIASADVLATPQETYFK 424
>M3K13_PONPY (Q5R8X7) Mitogen-activated protein kinase kinase kinase 13 (EC| 2.7.11.25) Length = 966 Score = 80.5 bits (197), Expect = 4e-15 Identities = 35/110 (31%), Positives = 62/110 (56%) Frame = -2 Query: 572 GTYRWMAPEMIQHRPYNQKVDVYSFGIVLWELITGTLPFPNMTAVQAAFAVVNKGVRPAI 393 GT W+APE+I++ P ++KVD++SFG+VLWEL+TG +P+ ++ + + V + + + Sbjct: 315 GTVAWLAPEVIRNEPVSEKVDIWSFGVVLWELLTGEIPYKDVDSSAIIWGVGSNSLHLPV 374 Query: 392 PHDCLPALGEIMTRCWDANPDVRPPFTDVARMLERVEIEVLNNVRKARFR 243 P C +M + W + P RP F L+ +VL ++ F+ Sbjct: 375 PSTCPDGFKILMKQTWQSKPRNRPSFRQTLMHLDIASADVLATPQETYFK 424
>FGFR1_DROME (Q07407) Fibroblast growth factor receptor homolog 1 precursor (EC| 2.7.10.1) (Protein heartless) Length = 729 Score = 80.1 bits (196), Expect = 5e-15 Identities = 34/94 (36%), Positives = 58/94 (61%), Gaps = 1/94 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +WMAPE +Q + Y+ K DV+S+GI+LWE++T G P+P + + + + + G R P Sbjct: 598 KWMAPESLQEKFYDSKSDVWSYGILLWEIMTYGQQPYPTIMSAEELYTYLMSGQRMEKPA 657 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLERV 285 C + +M +CW N D RPPFT++ ++++ Sbjct: 658 KCSMNIYILMRQCWHFNADDRPPFTEIVEYMDKL 691
>CTR1_ARATH (Q05609) Serine/threonine-protein kinase CTR1 (EC 2.7.11.1)| Length = 821 Score = 79.3 bits (194), Expect = 9e-15 Identities = 39/93 (41%), Positives = 52/93 (55%) Frame = -2 Query: 572 GTYRWMAPEMIQHRPYNQKVDVYSFGIVLWELITGTLPFPNMTAVQAAFAVVNKGVRPAI 393 GT WMAPE+++ P N+K DVYSFG++LWEL T P+ N+ Q AV K R I Sbjct: 713 GTPEWMAPEVLRDEPSNEKSDVYSFGVILWELATLQQPWGNLNPAQVVAAVGFKCKRLEI 772 Query: 392 PHDCLPALGEIMTRCWDANPDVRPPFTDVARML 294 P + P + I+ CW P RP F + +L Sbjct: 773 PRNLNPQVAAIIEGCWTNEPWKRPSFATIMDLL 805
>TNI3K_MOUSE (Q5GIG6) Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1)| (TNNI3-interacting kinase) (Cardiac ankyrin repeat kinase) Length = 833 Score = 78.2 bits (191), Expect = 2e-14 Identities = 38/102 (37%), Positives = 58/102 (56%), Gaps = 1/102 (0%) Frame = -2 Query: 593 EGMTPETGTYRWMAPEMI-QHRPYNQKVDVYSFGIVLWELITGTLPFPNMTAVQAAFAVV 417 + MT + G RWMAPE+ Q Y K DV+S+ + LWEL+ G +PF ++ AA + Sbjct: 617 DNMTKQPGNLRWMAPEVFTQCTRYTIKADVFSYALCLWELLIGEIPFAHLKPAAAAADMA 676 Query: 416 NKGVRPAIPHDCLPALGEIMTRCWDANPDVRPPFTDVARMLE 291 +RP I + + ++ R W+A P+ RP F++V R LE Sbjct: 677 YHHIRPPIGYSIPKPISSLLMRGWNACPEGRPEFSEVVRKLE 718
>MATK_HUMAN (P42679) Megakaryocyte-associated tyrosine-protein kinase (EC| 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase HYL) (Hematopoietic consensus tyrosine-lacking kinase) Length = 507 Score = 78.2 bits (191), Expect = 2e-14 Identities = 39/113 (34%), Positives = 62/113 (54%), Gaps = 1/113 (0%) Frame = -2 Query: 623 SEVARIEVKTEGMTPETGTYRWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNM 447 S+ + + +G+ +W APE ++H + K DV+SFG++LWE+ + G P+P M Sbjct: 369 SDFGLAKAERKGLDSSRLPVKWTAPEALKHGKFTSKSDVWSFGVLLWEVFSYGRAPYPKM 428 Query: 446 TAVQAAFAVVNKGVRPAIPHDCLPALGEIMTRCWDANPDVRPPFTDVARMLER 288 + + + A V KG R P C + +M+ CW+A P RPPF +A L R Sbjct: 429 SLKEVSEA-VEKGYRMEPPEGCPGPVHVLMSSCWEAEPARRPPFRKLAEKLAR 480
>M3LK7_DROME (P83104) Putative mitogen-activated protein kinase kinase kinase| 7-like (EC 2.7.11.25) Length = 393 Score = 78.2 bits (191), Expect = 2e-14 Identities = 39/103 (37%), Positives = 58/103 (56%), Gaps = 6/103 (5%) Frame = -2 Query: 584 TPETGTYRWMAPEMIQHRPYNQKVDVYSFGIVLWELITGTLPFPNMTAVQAAFAVV---- 417 T GT R+MAPE I+H Y K DVYSFGI+LWEL+T LP+ ++ + +A++ Sbjct: 164 TDMQGTLRYMAPEAIKHLKYTAKCDVYSFGIMLWELMTRQLPYSHLENPNSQYAIMKAIS 223 Query: 416 --NKGVRPAIPHDCLPALGEIMTRCWDANPDVRPPFTDVARML 294 K A+ DC + ++M C D NP+ RP ++ + L Sbjct: 224 SGEKLPMEAVRSDCPEGIKQLMECCMDINPEKRPSMKEIEKFL 266
>TNI3K_RAT (Q7TQP6) Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1)| (TNNI3-interacting kinase) (Cardiac ankyrin repeat kinase) Length = 834 Score = 78.2 bits (191), Expect = 2e-14 Identities = 38/102 (37%), Positives = 58/102 (56%), Gaps = 1/102 (0%) Frame = -2 Query: 593 EGMTPETGTYRWMAPEMI-QHRPYNQKVDVYSFGIVLWELITGTLPFPNMTAVQAAFAVV 417 + MT + G RWMAPE+ Q Y K DV+S+ + LWEL+TG +PF ++ AA + Sbjct: 618 DNMTKQPGNLRWMAPEVFTQCTRYTIKADVFSYSLCLWELLTGEIPFAHLKPAAAAADMA 677 Query: 416 NKGVRPAIPHDCLPALGEIMTRCWDANPDVRPPFTDVARMLE 291 +RP I + + ++ R W+A P+ RP F++V LE Sbjct: 678 YHHIRPPIGYSIPKPISSLLIRGWNACPEGRPEFSEVVSKLE 719
>PGFRB_HUMAN (P09619) Beta platelet-derived growth factor receptor precursor (EC| 2.7.10.1) (PDGF-R-beta) (CD140b antigen) Length = 1106 Score = 77.8 bits (190), Expect = 3e-14 Identities = 36/94 (38%), Positives = 56/94 (59%), Gaps = 1/94 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +WMAPE I + Y DV+SFGI+LWE+ T G P+P + + + + +G R A P Sbjct: 868 KWMAPESIFNSLYTTLSDVWSFGILLWEIFTLGGTPYPELPMNEQFYNAIKRGYRMAQPA 927 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLERV 285 + EIM +CW+ ++RPPF+ + +LER+ Sbjct: 928 HASDEIYEIMQKCWEEKFEIRPPFSQLVLLLERL 961
>FLK_RAT (P09760) Tyrosine-protein kinase FLK (EC 2.7.10.2) (Fragment)| Length = 323 Score = 77.8 bits (190), Expect = 3e-14 Identities = 37/98 (37%), Positives = 59/98 (60%), Gaps = 1/98 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +W APE + + Y+ + DV+SFGI+LWE + G P+P MT QA V +G R + P Sbjct: 226 KWTAPEALNYGRYSSESDVWSFGILLWETFSLGVCPYPGMTNQQAR-EQVERGYRMSAPQ 284 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLERVEIEV 273 +C + IM +CWD P+ RP F+D+ + L ++ ++ Sbjct: 285 NCPEEIFTIMMKCWDYKPENRPKFSDLHKELTAIKKKI 322
>PGFRB_CANFA (Q6QNF3) Beta platelet-derived growth factor receptor precursor (EC| 2.7.10.1) (PDGF-R-beta) Length = 1103 Score = 77.8 bits (190), Expect = 3e-14 Identities = 36/94 (38%), Positives = 56/94 (59%), Gaps = 1/94 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +WMAPE I + Y DV+SFGI+LWE+ T G P+P + + + + +G R A P Sbjct: 868 KWMAPESIFNSLYTTLSDVWSFGILLWEIFTLGGTPYPELPMNEQFYNAIKRGYRMAQPA 927 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLERV 285 + EIM +CW+ ++RPPF+ + +LER+ Sbjct: 928 HASDEIYEIMQKCWEEKFEIRPPFSQLVLLLERL 961
>KYK1_DICDI (P18160) Non-receptor tyrosine kinase spore lysis A (EC 2.7.10.2)| (Tyrosine-protein kinase 1) Length = 1584 Score = 77.4 bits (189), Expect = 3e-14 Identities = 39/102 (38%), Positives = 58/102 (56%) Frame = -2 Query: 587 MTPETGTYRWMAPEMIQHRPYNQKVDVYSFGIVLWELITGTLPFPNMTAVQAAFAVVNKG 408 MT G +MAPE+ + ++K DVYS+G+VL+EL+T P +M ++ A + Sbjct: 1462 MTQSVGCIPYMAPEVFKGDSNSEKSDVYSYGMVLFELLTSDEPQQDMKPMKMAHLAAYES 1521 Query: 407 VRPAIPHDCLPALGEIMTRCWDANPDVRPPFTDVARMLERVE 282 RP IP EI+T+CWD+NPD RP F + L+ +E Sbjct: 1522 YRPPIPLTTSSKWKEILTQCWDSNPDSRPTFKQIIVHLKEME 1563
>TNI3K_HUMAN (Q59H18) Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1)| (TNNI3-interacting kinase) (Cardiac ankyrin repeat kinase) Length = 936 Score = 77.4 bits (189), Expect = 3e-14 Identities = 37/102 (36%), Positives = 58/102 (56%), Gaps = 1/102 (0%) Frame = -2 Query: 593 EGMTPETGTYRWMAPEMI-QHRPYNQKVDVYSFGIVLWELITGTLPFPNMTAVQAAFAVV 417 + MT + G RWMAPE+ Q Y K DV+S+ + LWE++TG +PF ++ AA + Sbjct: 720 DNMTKQPGNLRWMAPEVFTQCTRYTIKADVFSYALCLWEILTGEIPFAHLKPAAAAADMA 779 Query: 416 NKGVRPAIPHDCLPALGEIMTRCWDANPDVRPPFTDVARMLE 291 +RP I + + ++ R W+A P+ RP F++V LE Sbjct: 780 YHHIRPPIGYSIPKPISSLLIRGWNACPEGRPEFSEVVMKLE 821
>FGFR4_HUMAN (P22455) Fibroblast growth factor receptor 4 precursor (EC| 2.7.10.1) (FGFR-4) (CD334 antigen) Length = 802 Score = 76.6 bits (187), Expect = 6e-14 Identities = 39/98 (39%), Positives = 57/98 (58%), Gaps = 1/98 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +WMAPE + R Y + DV+SFGI+LWE+ T G P+P + V+ F+++ +G R P Sbjct: 654 KWMAPEALFDRVYTHQSDVWSFGILLWEIFTLGGSPYPGI-PVEELFSLLREGHRMDRPP 712 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLERVEIEV 273 C P L +M CW A P RP F + L++V + V Sbjct: 713 HCPPELYGLMRECWHAAPSQRPTFKQLVEALDKVLLAV 750
>FER_HUMAN (P16591) Proto-oncogene tyrosine-protein kinase FER (EC 2.7.10.2)| (p94-FER) (c-FER) Length = 822 Score = 76.3 bits (186), Expect = 8e-14 Identities = 36/91 (39%), Positives = 55/91 (60%), Gaps = 1/91 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +W APE + + Y+ + DV+SFGI+LWE + G P+P MT QA V +G R + P Sbjct: 725 KWTAPEALNYGRYSSESDVWSFGILLWETFSLGVCPYPGMTNQQAR-EQVERGYRMSAPQ 783 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARML 294 C + +IM +CWD P+ RP F+++ + L Sbjct: 784 HCPEDISKIMMKCWDYKPENRPKFSELQKEL 814
>PGFRB_RAT (Q05030) Beta platelet-derived growth factor receptor precursor (EC| 2.7.10.1) (PDGF-R-beta) Length = 1097 Score = 75.9 bits (185), Expect = 1e-13 Identities = 36/94 (38%), Positives = 54/94 (57%), Gaps = 1/94 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +WMAPE I + Y DV+SFGI+LWE+ T G P+P + + + +G R A P Sbjct: 867 KWMAPESIFNSLYTTLSDVWSFGILLWEIFTLGGTPYPELPMNDQFYNAIKRGYRMAQPA 926 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLERV 285 + EIM +CW+ + RPPF+ + +LER+ Sbjct: 927 HASDEIYEIMQKCWEEKFETRPPFSQLVLLLERL 960
>PGFRB_MOUSE (P05622) Beta platelet-derived growth factor receptor precursor (EC| 2.7.10.1) (PDGF-R-beta) Length = 1098 Score = 75.9 bits (185), Expect = 1e-13 Identities = 36/94 (38%), Positives = 54/94 (57%), Gaps = 1/94 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +WMAPE I + Y DV+SFGI+LWE+ T G P+P + + + +G R A P Sbjct: 867 KWMAPESIFNSLYTTLSDVWSFGILLWEIFTLGGTPYPELPMNDQFYNAIKRGYRMAQPA 926 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLERV 285 + EIM +CW+ + RPPF+ + +LER+ Sbjct: 927 HASDEIYEIMQKCWEEKFETRPPFSQLVLLLERL 960
>CAD96_DROME (Q9VBW3) Tyrosine kinase receptor Cad96Ca precursor (EC 2.7.10.1)| (Cadherin 96Ca) (Tyrosine kinase receptor HD-14) Length = 773 Score = 75.9 bits (185), Expect = 1e-13 Identities = 43/130 (33%), Positives = 71/130 (54%), Gaps = 1/130 (0%) Frame = -2 Query: 632 LLTSEVARIEVKTEGMTPETGTYRWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPF 456 ++TS++ E K+EG P RWMA E + ++ K D++SFGI++WE++T G+ P+ Sbjct: 635 VITSKI--YERKSEGKLP----IRWMATESLYDNIFSVKSDIWSFGILMWEIVTLGSTPY 688 Query: 455 PNMTAVQAAFAVVNKGVRPAIPHDCLPALGEIMTRCWDANPDVRPPFTDVARMLERVEIE 276 P ++A V G R P C L IM CW +P RP F ++ +ML+++ Sbjct: 689 PGISAAD-VMRKVRDGYRLEKPEHCRRELYNIMYYCWSHDPQERPLFAEIIQMLDKLLHT 747 Query: 275 VLNNVRKARF 246 ++ + RF Sbjct: 748 EMDYIELERF 757
>KIT_BOVIN (P43481) Mast/stem cell growth factor receptor precursor (EC| 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) Length = 977 Score = 75.5 bits (184), Expect = 1e-13 Identities = 37/109 (33%), Positives = 59/109 (54%), Gaps = 1/109 (0%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +WMAPE I + Y + DV+S+GI LWEL + G+ P+P M + ++ +G R P Sbjct: 835 KWMAPESIFNCVYTFESDVWSYGIFLWELFSLGSSPYPGMPVDSKFYKMIKEGFRMLSPE 894 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLERVEIEVLNNVRKARFRC 240 + +IM CWDA+P RP F + +++E+ E N++ C Sbjct: 895 HAPAEMYDIMKTCWDADPLKRPTFKQIVQLIEKQISESTNHIYSNLANC 943
>M3K7_MOUSE (Q62073) Mitogen-activated protein kinase kinase kinase 7 (EC| 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1) Length = 579 Score = 75.5 bits (184), Expect = 1e-13 Identities = 37/100 (37%), Positives = 59/100 (59%), Gaps = 2/100 (2%) Frame = -2 Query: 587 MTPETGTYRWMAPEMIQHRPYNQKVDVYSFGIVLWELITGTLPFPNM--TAVQAAFAVVN 414 MT G+ WMAPE+ + Y++K DV+S+GI+LWE+IT PF + A + +AV N Sbjct: 186 MTNNKGSAAWMAPEVFEGSNYSEKCDVFSWGIILWEVITRRKPFDEIGGPAFRIMWAVHN 245 Query: 413 KGVRPAIPHDCLPALGEIMTRCWDANPDVRPPFTDVARML 294 G RP + + + +MTRCW +P RP ++ +++ Sbjct: 246 -GTRPPLIKNLPKPIESLMTRCWSKDPSQRPSMEEIVKIM 284
>KIT_HUMAN (P10721) Mast/stem cell growth factor receptor precursor (EC| 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) (CD117 antigen) Length = 976 Score = 75.5 bits (184), Expect = 1e-13 Identities = 37/109 (33%), Positives = 59/109 (54%), Gaps = 1/109 (0%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +WMAPE I + Y + DV+S+GI LWEL + G+ P+P M + ++ +G R P Sbjct: 834 KWMAPESIFNCVYTFESDVWSYGIFLWELFSLGSSPYPGMPVDSKFYKMIKEGFRMLSPE 893 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLERVEIEVLNNVRKARFRC 240 + +IM CWDA+P RP F + +++E+ E N++ C Sbjct: 894 HAPAEMYDIMKTCWDADPLKRPTFKQIVQLIEKQISESTNHIYSNLANC 942
>KIT_CAPHI (Q28317) Mast/stem cell growth factor receptor precursor (EC| 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) Length = 978 Score = 75.5 bits (184), Expect = 1e-13 Identities = 37/109 (33%), Positives = 59/109 (54%), Gaps = 1/109 (0%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +WMAPE I + Y + DV+S+GI LWEL + G+ P+P M + ++ +G R P Sbjct: 836 KWMAPESIFNCVYTFESDVWSYGIFLWELFSLGSSPYPGMPVDSKFYKMIKEGFRMLSPE 895 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLERVEIEVLNNVRKARFRC 240 + +IM CWDA+P RP F + +++E+ E N++ C Sbjct: 896 HAPAEMYDIMKTCWDADPLKRPTFKQIVQLIEKQISESTNHIYSNLANC 944
>M3K7_HUMAN (O43318) Mitogen-activated protein kinase kinase kinase 7 (EC| 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1) Length = 606 Score = 75.5 bits (184), Expect = 1e-13 Identities = 37/100 (37%), Positives = 59/100 (59%), Gaps = 2/100 (2%) Frame = -2 Query: 587 MTPETGTYRWMAPEMIQHRPYNQKVDVYSFGIVLWELITGTLPFPNM--TAVQAAFAVVN 414 MT G+ WMAPE+ + Y++K DV+S+GI+LWE+IT PF + A + +AV N Sbjct: 186 MTNNKGSAAWMAPEVFEGSNYSEKCDVFSWGIILWEVITRRKPFDEIGGPAFRIMWAVHN 245 Query: 413 KGVRPAIPHDCLPALGEIMTRCWDANPDVRPPFTDVARML 294 G RP + + + +MTRCW +P RP ++ +++ Sbjct: 246 -GTRPPLIKNLPKPIESLMTRCWSKDPSQRPSMEEIVKIM 284
>KIT_CHICK (Q08156) Mast/stem cell growth factor receptor precursor (EC| 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) Length = 960 Score = 75.1 bits (183), Expect = 2e-13 Identities = 35/93 (37%), Positives = 56/93 (60%), Gaps = 1/93 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +WMAPE I + Y + DV+S+GI+LWEL + G+ P+P M + ++ +G R P Sbjct: 819 KWMAPESIFNCVYTFESDVWSYGILLWELFSLGSSPYPGMPVDSKFYKMIKEGYRMFSPE 878 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLER 288 P + +IM CWDA+P RP F + +++E+ Sbjct: 879 CSPPEMYDIMKSCWDADPLQRPTFKQIVQLIEQ 911
>FGFR4_RAT (Q498D6) Fibroblast growth factor receptor 4 precursor (EC| 2.7.10.1) (FGFR-4) Length = 800 Score = 74.7 bits (182), Expect = 2e-13 Identities = 38/98 (38%), Positives = 57/98 (58%), Gaps = 1/98 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +WMAPE + R Y + DV+SFGI+LWE+ T G P+P + V+ F+++ +G R P Sbjct: 652 KWMAPEALFDRVYTHQSDVWSFGILLWEIFTLGGSPYPGI-PVEELFSLLREGHRMERPP 710 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLERVEIEV 273 +C L +M CW A P RP F + L++V + V Sbjct: 711 NCPSELYGLMRECWHAAPSQRPTFKQLVEALDKVLLAV 748
>UFO_HUMAN (P30530) Tyrosine-protein kinase receptor UFO precursor (EC| 2.7.10.1) (AXL oncogene) Length = 887 Score = 74.3 bits (181), Expect = 3e-13 Identities = 36/92 (39%), Positives = 54/92 (58%), Gaps = 1/92 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +W+A E + R Y K DV+SFG+ +WE+ T G P+P + + + + +G R P Sbjct: 707 KWIAIESLADRVYTSKSDVWSFGVTMWEIATRGQTPYPGVENSEI-YDYLRQGNRLKQPA 765 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLE 291 DCL L +M+RCW+ NP RP FT++ LE Sbjct: 766 DCLDGLYALMSRCWELNPQDRPSFTELREDLE 797
>KIT_FELCA (Q28889) Mast/stem cell growth factor receptor precursor (EC| 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) Length = 978 Score = 74.3 bits (181), Expect = 3e-13 Identities = 36/109 (33%), Positives = 59/109 (54%), Gaps = 1/109 (0%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +WMAPE I + Y + DV+S+GI LWEL + G+ P+P M + ++ +G R P Sbjct: 835 KWMAPESIFNCVYTFESDVWSYGIFLWELFSLGSSPYPGMPVDSKFYKMIKEGFRMLSPE 894 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLERVEIEVLNNVRKARFRC 240 + +IM CWDA+P RP F + +++E+ + N++ C Sbjct: 895 HAPAEMYDIMKTCWDADPLKRPTFKQIVQLIEKQISDSTNHIYSNLANC 943
>KIT_CANFA (O97799) Mast/stem cell growth factor receptor precursor (EC| 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) Length = 975 Score = 74.3 bits (181), Expect = 3e-13 Identities = 36/109 (33%), Positives = 59/109 (54%), Gaps = 1/109 (0%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +WMAPE I + Y + DV+S+GI LWEL + G+ P+P M + ++ +G R P Sbjct: 833 KWMAPESIFNCVYTFESDVWSYGIFLWELFSLGSSPYPGMPVDSKFYKMIKEGFRMLSPE 892 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLERVEIEVLNNVRKARFRC 240 + +IM CWDA+P RP F + +++E+ + N++ C Sbjct: 893 HAPAEMYDIMKTCWDADPLKRPTFKQIVQLIEKQISDSTNHIYSNLANC 941
>CSK_HUMAN (P41240) Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase)| (Protein-tyrosine kinase CYL) Length = 450 Score = 74.3 bits (181), Expect = 3e-13 Identities = 38/114 (33%), Positives = 63/114 (55%), Gaps = 3/114 (2%) Frame = -2 Query: 599 KTEGMTPETGTY--RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAA 429 K T +TG +W APE ++ + ++ K DV+SFGI+LWE+ + G +P+P + ++ Sbjct: 337 KEASSTQDTGKLPVKWTAPEALREKKFSTKSDVWSFGILLWEIYSFGRVPYPRI-PLKDV 395 Query: 428 FAVVNKGVRPAIPHDCLPALGEIMTRCWDANPDVRPPFTDVARMLERVEIEVLN 267 V KG + P C PA+ E+M CW + +RP F + LE ++ L+ Sbjct: 396 VPRVEKGYKMDAPDGCPPAVYEVMKNCWHLDAAMRPSFLQLREQLEHIKTHELH 449
>MATK_RAT (P41243) Megakaryocyte-associated tyrosine-protein kinase (EC| 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase BATK) Length = 467 Score = 73.9 bits (180), Expect = 4e-13 Identities = 38/111 (34%), Positives = 63/111 (56%), Gaps = 1/111 (0%) Frame = -2 Query: 617 VARIEVKTEGMTPETGTYRWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTA 441 +A+ E++ +G+ +W APE +++ ++ K DV+SFG++LWE+ + G P+P M+ Sbjct: 332 LAKAELR-KGLDSSRLPVKWTAPEALKNGRFSSKSDVWSFGVLLWEVFSYGRAPYPKMSL 390 Query: 440 VQAAFAVVNKGVRPAIPHDCLPALGEIMTRCWDANPDVRPPFTDVARMLER 288 + + A V KG R P C + +M CW+A P RPPF + L R Sbjct: 391 KEVSEA-VEKGYRMEPPDSCPGPVHTLMGSCWEAEPSRRPPFRKIVEKLGR 440
>MATK_MOUSE (P41242) Megakaryocyte-associated tyrosine-protein kinase (EC| 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase NTK) Length = 505 Score = 73.9 bits (180), Expect = 4e-13 Identities = 37/113 (32%), Positives = 62/113 (54%), Gaps = 1/113 (0%) Frame = -2 Query: 623 SEVARIEVKTEGMTPETGTYRWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNM 447 S+ + + +G+ +W APE +++ ++ K DV+SFG++LWE+ + G P+P M Sbjct: 367 SDFGLAKAERKGLDSSRLPVKWTAPEALKNGRFSSKSDVWSFGVLLWEVFSYGRAPYPKM 426 Query: 446 TAVQAAFAVVNKGVRPAIPHDCLPALGEIMTRCWDANPDVRPPFTDVARMLER 288 + + + A V KG R P C ++ +M CW+A P RPPF + L R Sbjct: 427 SLKEVSEA-VEKGYRMEPPDGCPGSVHTLMGSCWEAEPARRPPFRKIVEKLGR 478
>EPHA6_RAT (P54758) Ephrin type-A receptor 6 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2) Length = 1035 Score = 73.6 bits (179), Expect = 5e-13 Identities = 40/119 (33%), Positives = 63/119 (52%), Gaps = 1/119 (0%) Frame = -2 Query: 638 SRLLTSEVARIEVKTEGMTPETGTYRWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTL 462 SR+L + T G P RW APE I +R ++ DV+S+GIV+WE+++ G Sbjct: 819 SRVLEDDPEAAYTTTGGKIP----IRWTAPEAIAYRKFSSASDVWSYGIVMWEVMSYGER 874 Query: 461 PFPNMTAVQAAFAVVNKGVRPAIPHDCLPALGEIMTRCWDANPDVRPPFTDVARMLERV 285 P+ M+ Q + +G R P C P+L ++M CW + RP FTD+ L+++ Sbjct: 875 PYWEMSN-QDVILSIEEGYRLPAPMGCPPSLHQLMLHCWQKERNHRPKFTDIVSFLDKL 932
>FGFR3_HUMAN (P22607) Fibroblast growth factor receptor 3 precursor (EC| 2.7.10.1) (FGFR-3) (CD333 antigen) Length = 806 Score = 73.6 bits (179), Expect = 5e-13 Identities = 38/94 (40%), Positives = 54/94 (57%), Gaps = 1/94 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +WMAPE + R Y + DV+SFG++LWE+ T G P+P + V+ F ++ +G R P Sbjct: 659 KWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGI-PVEELFKLLKEGHRMDKPA 717 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLERV 285 +C L IM CW A P RP F + L+RV Sbjct: 718 NCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRV 751
>EPHA5_RAT (P54757) Ephrin type-A receptor 5 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) Length = 1005 Score = 73.6 bits (179), Expect = 5e-13 Identities = 37/94 (39%), Positives = 54/94 (57%), Gaps = 1/94 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 RW APE I R + DV+S+GIV+WE+++ G P+ MT Q V +G R P Sbjct: 845 RWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTN-QDVIKAVEEGYRLPSPM 903 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLERV 285 DC AL ++M CW + + RP F D+ ML+++ Sbjct: 904 DCPAALYQLMLDCWQKDRNSRPKFDDIVNMLDKL 937
>KIT_FSVHZ (P04048) Tyrosine-protein kinase transforming protein kit (EC| 2.7.10.1) Length = 370 Score = 73.2 bits (178), Expect = 6e-13 Identities = 34/93 (36%), Positives = 54/93 (58%), Gaps = 1/93 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +WMAPE I + Y + DV+S+GI LWEL + G+ P+P M + ++ +G R P Sbjct: 272 KWMAPESIFNCVYTFESDVWSYGIFLWELFSLGSSPYPGMPVDSKFYKMIKEGFRMLSPE 331 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLER 288 + +IM CWDA+P RP F + +++E+ Sbjct: 332 HAPAEMYDIMKTCWDADPLKRPTFKQIVQLIEK 364
>CEK2_CHICK (P18460) Tyrosine kinase receptor CEK2 precursor (EC 2.7.10.1)| Length = 806 Score = 73.2 bits (178), Expect = 6e-13 Identities = 38/94 (40%), Positives = 54/94 (57%), Gaps = 1/94 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +WMAPE + R Y + DV+SFG++LWE+ T G P+P + V+ F ++ +G R P Sbjct: 653 KWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGI-PVEELFKLLKEGHRMDKPA 711 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLERV 285 +C L IM CW A P RP F + L+RV Sbjct: 712 NCTHDLYMIMRECWHAVPSQRPTFKQLVEDLDRV 745
>KIT_MOUSE (P05532) Mast/stem cell growth factor receptor precursor (EC| 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) Length = 975 Score = 72.8 bits (177), Expect = 8e-13 Identities = 34/93 (36%), Positives = 53/93 (56%), Gaps = 1/93 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +WMAPE I Y + DV+S+GI LWEL + G+ P+P M + ++ +G R P Sbjct: 832 KWMAPESIFSCVYTFESDVWSYGIFLWELFSLGSSPYPGMPVDSKFYKMIKEGFRMVSPE 891 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLER 288 + ++M CWDA+P RP F V +++E+ Sbjct: 892 HAPAEMYDVMKTCWDADPLKRPTFKQVVQLIEK 924
>SRK3_SPOLA (P42689) Tyrosine-protein kinase SRK3 (EC 2.7.10.2) (Fragment)| Length = 334 Score = 72.4 bits (176), Expect = 1e-12 Identities = 42/113 (37%), Positives = 62/113 (54%), Gaps = 4/113 (3%) Frame = -2 Query: 617 VARIEVKTEGMTPETGT---YRWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPN 450 +AR+ +K + P GT +W APE + + K DV+SFG+++ E++T G +P+P Sbjct: 207 LARV-IKEDIYNPREGTKFPIKWTAPEAALYNRFTIKSDVWSFGVLISEIVTHGRMPYPG 265 Query: 449 MTAVQAAFAVVNKGVRPAIPHDCLPALGEIMTRCWDANPDVRPPFTDVARMLE 291 MT Q AV ++G R P C L +IM CW PD RP F + +LE Sbjct: 266 MTNRQVLEAV-DRGYRMPCPEGCPDPLYKIMLSCWKHEPDDRPTFESLKNLLE 317
>CSK_RAT (P32577) Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase)| Length = 450 Score = 72.4 bits (176), Expect = 1e-12 Identities = 37/114 (32%), Positives = 61/114 (53%), Gaps = 3/114 (2%) Frame = -2 Query: 599 KTEGMTPETGTY--RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAA 429 K T +TG +W APE ++ + ++ K DV+SFGI+LWE+ + G +P+P + ++ Sbjct: 337 KEASSTQDTGKLPVKWTAPEALREKKFSTKSDVWSFGILLWEIYSFGRVPYPRI-PLKDV 395 Query: 428 FAVVNKGVRPAIPHDCLPALGEIMTRCWDANPDVRPPFTDVARMLERVEIEVLN 267 V KG + P C PA+ ++M CW + RP F + LE + L+ Sbjct: 396 VPRVEKGYKMDAPDGCPPAVYDVMKNCWHLDAATRPTFLQLREQLEHIRTHELH 449
>TIE1_BRARE (O73792) Tyrosine-protein kinase receptor Tie-1 (EC 2.7.10.1)| (Fragment) Length = 184 Score = 72.4 bits (176), Expect = 1e-12 Identities = 38/107 (35%), Positives = 60/107 (56%), Gaps = 1/107 (0%) Frame = -2 Query: 599 KTEGMTPETGTYRWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFA 423 KT G P RWMA E + + Y K DV+SFG++LWE+++ G P+ MT + + Sbjct: 56 KTMGRLP----VRWMAIESLNYSVYTTKSDVWSFGVLLWEIVSLGGTPYCGMTCAE-LYE 110 Query: 422 VVNKGVRPAIPHDCLPALGEIMTRCWDANPDVRPPFTDVARMLERVE 282 + +G R P +C + E+M +CW P RPPF+ ++ L R++ Sbjct: 111 KLPQGYRMEQPRNCDDEVYELMRQCWRDRPYERPPFSQISVQLNRMQ 157
>FGFR3_MOUSE (Q61851) Fibroblast growth factor receptor 3 precursor (EC| 2.7.10.1) (FGFR-3) (Heparin-binding growth factor receptor) Length = 801 Score = 72.4 bits (176), Expect = 1e-12 Identities = 37/95 (38%), Positives = 53/95 (55%), Gaps = 2/95 (2%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT--GTLPFPNMTAVQAAFAVVNKGVRPAIP 390 +WMAPE + R Y + DV+SFG++LWE+ T G P+P + V+ F ++ +G R P Sbjct: 653 KWMAPEALFDRVYTHQSDVWSFGVLLWEIFTPGGPSPYPGI-PVEELFKLLKEGHRMDKP 711 Query: 389 HDCLPALGEIMTRCWDANPDVRPPFTDVARMLERV 285 C L IM CW A P RP F + L+R+ Sbjct: 712 ASCTHDLYMIMRECWHAVPSQRPTFKQLVEDLDRI 746
>EPHA6_MOUSE (Q62413) Ephrin type-A receptor 6 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2) Length = 1035 Score = 72.0 bits (175), Expect = 1e-12 Identities = 39/119 (32%), Positives = 62/119 (52%), Gaps = 1/119 (0%) Frame = -2 Query: 638 SRLLTSEVARIEVKTEGMTPETGTYRWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTL 462 SR+L + T G P RW APE I +R ++ D +S+GIV+WE+++ G Sbjct: 819 SRVLEDDPEAAYTTTGGKIP----IRWTAPEAIAYRKFSSASDAWSYGIVMWEVMSYGER 874 Query: 461 PFPNMTAVQAAFAVVNKGVRPAIPHDCLPALGEIMTRCWDANPDVRPPFTDVARMLERV 285 P+ M+ Q + +G R P C P+L ++M CW + RP FTD+ L+++ Sbjct: 875 PYWEMSN-QDVILSIEEGYRLPAPMGCPPSLQQLMLHCWQKERNHRPKFTDIVSFLDKL 932
>VGFR3_RAT (Q91ZT1) Vascular endothelial growth factor receptor 3 precursor (EC| 2.7.10.1) (VEGFR-3) (Tyrosine-protein kinase receptor FLT4) Length = 1363 Score = 72.0 bits (175), Expect = 1e-12 Identities = 33/91 (36%), Positives = 50/91 (54%), Gaps = 1/91 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +WMAPE I + Y + DV+SFG++LWE+ + G P+P + + + G R P Sbjct: 1079 KWMAPESIFDKVYTTQSDVWSFGVLLWEIFSLGASPYPGVQINEEFCQRLKDGTRMRAPE 1138 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARML 294 PA+ IM CW +P RP F+D+ +L Sbjct: 1139 LATPAIRHIMQSCWSGDPKARPAFSDLVEIL 1169
>VGFR3_MOUSE (P35917) Vascular endothelial growth factor receptor 3 precursor (EC| 2.7.10.1) (VEGFR-3) (Tyrosine-protein kinase receptor FLT4) Length = 1363 Score = 72.0 bits (175), Expect = 1e-12 Identities = 33/91 (36%), Positives = 50/91 (54%), Gaps = 1/91 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +WMAPE I + Y + DV+SFG++LWE+ + G P+P + + + G R P Sbjct: 1079 KWMAPESIFDKVYTTQSDVWSFGVLLWEIFSLGASPYPGVQINEEFCQRLKDGTRMRAPE 1138 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARML 294 PA+ IM CW +P RP F+D+ +L Sbjct: 1139 LATPAIRHIMQSCWSGDPKARPAFSDLVEIL 1169
>TIE1_HUMAN (P35590) Tyrosine-protein kinase receptor Tie-1 precursor (EC| 2.7.10.1) Length = 1138 Score = 72.0 bits (175), Expect = 1e-12 Identities = 39/106 (36%), Positives = 58/106 (54%), Gaps = 1/106 (0%) Frame = -2 Query: 599 KTEGMTPETGTYRWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFA 423 KT G P RWMA E + + Y K DV+SFG++LWE+++ G P+ MT + + Sbjct: 1010 KTMGRLP----VRWMAIESLNYSVYTTKSDVWSFGVLLWEIVSLGGTPYCGMTCAE-LYE 1064 Query: 422 VVNKGVRPAIPHDCLPALGEIMTRCWDANPDVRPPFTDVARMLERV 285 + +G R P +C + E+M +CW P RPPF +A L R+ Sbjct: 1065 KLPQGYRMEQPRNCDDEVYELMRQCWRDRPYERPPFAQIALQLGRM 1110
>EPHA5_MOUSE (Q60629) Ephrin type-A receptor 5 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Brain-specific kinase) (CEK-7) Length = 877 Score = 72.0 bits (175), Expect = 1e-12 Identities = 36/94 (38%), Positives = 54/94 (57%), Gaps = 1/94 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 RW APE I R + DV+S+GIV+WE+++ G P+ MT Q V +G R P Sbjct: 682 RWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTN-QDVIKAVEEGYRLPSPM 740 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLERV 285 DC AL ++M CW + + RP F ++ ML+++ Sbjct: 741 DCPAALYQLMLDCWQKDRNSRPKFDEIVNMLDKL 774
>EPHA2_HUMAN (P29317) Ephrin type-A receptor 2 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase) Length = 976 Score = 72.0 bits (175), Expect = 1e-12 Identities = 40/119 (33%), Positives = 63/119 (52%), Gaps = 1/119 (0%) Frame = -2 Query: 638 SRLLTSEVARIEVKTEGMTPETGTYRWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTL 462 SR+L + + G P RW APE I +R + DV+SFGIV+WE++T G Sbjct: 761 SRVLEDDPEATYTTSGGKIP----IRWTAPEAISYRKFTSASDVWSFGIVMWEVMTYGER 816 Query: 461 PFPNMTAVQAAFAVVNKGVRPAIPHDCLPALGEIMTRCWDANPDVRPPFTDVARMLERV 285 P+ ++ + A +N G R P DC A+ ++M +CW RP F D+ +L+++ Sbjct: 817 PYWELSNHEVMKA-INDGFRLPTPMDCPSAIYQLMMQCWQQERARRPKFADIVSILDKL 874
>TIE1_MOUSE (Q06806) Tyrosine-protein kinase receptor Tie-1 precursor (EC| 2.7.10.1) Length = 1134 Score = 72.0 bits (175), Expect = 1e-12 Identities = 39/106 (36%), Positives = 58/106 (54%), Gaps = 1/106 (0%) Frame = -2 Query: 599 KTEGMTPETGTYRWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFA 423 KT G P RWMA E + + Y K DV+SFG++LWE+++ G P+ MT + + Sbjct: 1006 KTMGRLP----VRWMAIESLNYSVYTTKSDVWSFGVLLWEIVSLGGTPYCGMTCAE-LYE 1060 Query: 422 VVNKGVRPAIPHDCLPALGEIMTRCWDANPDVRPPFTDVARMLERV 285 + +G R P +C + E+M +CW P RPPF +A L R+ Sbjct: 1061 KLPQGYRMEQPRNCDDEVYELMRQCWRDRPYERPPFAQIALQLGRM 1106
>M3K7_DROME (Q9V3Q6) Mitogen-activated protein kinase kinase kinase 7 (EC| 2.7.11.25) (TGF-beta-activated kinase 1) (dTAK1) Length = 678 Score = 72.0 bits (175), Expect = 1e-12 Identities = 36/124 (29%), Positives = 62/124 (50%), Gaps = 1/124 (0%) Frame = -2 Query: 653 LVINRSR-LLTSEVARIEVKTEGMTPETGTYRWMAPEMIQHRPYNQKVDVYSFGIVLWEL 477 L+ N+ R L + + K+ MT G+ WMAPE+ + Y +K D++S+ IVLWE+ Sbjct: 147 LLTNKGRNLKICDFGTVADKSTMMTNNRGSAAWMAPEVFEGSKYTEKCDIFSWAIVLWEV 206 Query: 476 ITGTLPFPNMTAVQAAFAVVNKGVRPAIPHDCLPALGEIMTRCWDANPDVRPPFTDVARM 297 ++ PF + + KG RP + C + ++MT CW P+ RP + + Sbjct: 207 LSRKQPFKGIDNAYTIQWKIYKGERPPLLTTCPKRIEDLMTACWKTVPEDRPSMQYIVGV 266 Query: 296 LERV 285 + + Sbjct: 267 MHEI 270
>EPHA5_HUMAN (P54756) Ephrin type-A receptor 5 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Receptor protein-tyrosine kinase HEK7) Length = 1037 Score = 71.6 bits (174), Expect = 2e-12 Identities = 36/94 (38%), Positives = 53/94 (56%), Gaps = 1/94 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 RW APE I R + DV+S+GIV+WE+++ G P+ MT Q V +G R P Sbjct: 843 RWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTN-QDVIKAVEEGYRLPSPM 901 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLERV 285 DC AL ++M CW + RP F ++ ML+++ Sbjct: 902 DCPAALYQLMLDCWQKERNSRPKFDEIVNMLDKL 935
>FGFR4_MOUSE (Q03142) Fibroblast growth factor receptor 4 precursor (EC| 2.7.10.1) (FGFR-4) (Protein-tyrosine kinase receptor MPK-11) Length = 799 Score = 71.6 bits (174), Expect = 2e-12 Identities = 37/98 (37%), Positives = 56/98 (57%), Gaps = 1/98 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +WMAPE + R Y + DV+SF I+LWE+ T G P+P + V+ F+++ +G R P Sbjct: 651 KWMAPEALFDRVYTHQSDVWSFEILLWEIFTLGGSPYPGI-PVEELFSLLREGHRMERPP 709 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLERVEIEV 273 +C L +M CW A P RP F + L++V + V Sbjct: 710 NCPSELYGLMRECWHAAPSQRPTFKQLVEALDKVLLAV 747
>EPHA2_MOUSE (Q03145) Ephrin type-A receptor 2 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase) (MPK-5) (SEK-2) Length = 977 Score = 71.6 bits (174), Expect = 2e-12 Identities = 39/119 (32%), Positives = 63/119 (52%), Gaps = 1/119 (0%) Frame = -2 Query: 638 SRLLTSEVARIEVKTEGMTPETGTYRWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTL 462 SR+L + + G P RW APE I +R + DV+S+GIV+WE++T G Sbjct: 762 SRVLEDDPEATYTTSGGKIP----IRWTAPEAISYRKFTSASDVWSYGIVMWEVMTYGER 817 Query: 461 PFPNMTAVQAAFAVVNKGVRPAIPHDCLPALGEIMTRCWDANPDVRPPFTDVARMLERV 285 P+ ++ + A +N G R P DC A+ ++M +CW RP F D+ +L+++ Sbjct: 818 PYWELSNHEVMKA-INDGFRLPTPMDCPSAIYQLMMQCWQQERSRRPKFADIVSILDKL 875
>FGFR1_CHICK (P21804) Basic fibroblast growth factor receptor 1 precursor (EC| 2.7.10.1) Length = 819 Score = 71.2 bits (173), Expect = 2e-12 Identities = 36/94 (38%), Positives = 54/94 (57%), Gaps = 1/94 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +WMAPE + R Y + DV+SFG++LWE+ T G P+P + V+ F ++ +G R P Sbjct: 663 KWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGV-PVEELFKLLKEGHRMDKPS 721 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLERV 285 +C L +M CW A P RP F + L+R+ Sbjct: 722 NCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRI 755
>PHY1_CERPU (P25848) Light-sensor Protein kinase [Includes: Phytochrome; Protein| kinase (EC 2.7.11.1)] Length = 1307 Score = 71.2 bits (173), Expect = 2e-12 Identities = 40/109 (36%), Positives = 57/109 (52%), Gaps = 15/109 (13%) Frame = -2 Query: 572 GTYRWMAPEMI---------------QHRPYNQKVDVYSFGIVLWELITGTLPFPNMTAV 438 GT RWMAPE+I + Y K DVYSFG+V +E++TG +PFP Sbjct: 1175 GTNRWMAPEVINLGYESTEGEISFDGKVPKYPLKSDVYSFGMVCYEVLTGDVPFPEEKNP 1234 Query: 437 QAAFAVVNKGVRPAIPHDCLPALGEIMTRCWDANPDVRPPFTDVARMLE 291 +V +GVRP +P C L ++T CW+ +P RP F + + L+ Sbjct: 1235 NNVKRMVLEGVRPDLPAHCPIELKALITDCWNQDPLKRPSFAVICQKLK 1283
>RET_MOUSE (P35546) Proto-oncogene tyrosine-protein kinase receptor ret| precursor (EC 2.7.10.1) (C-ret) Length = 1115 Score = 71.2 bits (173), Expect = 2e-12 Identities = 36/109 (33%), Positives = 62/109 (56%), Gaps = 1/109 (0%) Frame = -2 Query: 599 KTEGMTPETGTYRWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFA 423 K++G P +WMA E + Y + DV+SFG++LWE++T G P+P + + F Sbjct: 909 KSKGRIP----VKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPP-ERLFN 963 Query: 422 VVNKGVRPAIPHDCLPALGEIMTRCWDANPDVRPPFTDVARMLERVEIE 276 ++ G R P +C + +M +CW PD RP F D+++ LE++ ++ Sbjct: 964 LLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADISKDLEKMMVK 1012
>FGFR1_MOUSE (P16092) Basic fibroblast growth factor receptor 1 precursor (EC| 2.7.10.1) (FGFR-1) (bFGF-R) (MFR) Length = 822 Score = 71.2 bits (173), Expect = 2e-12 Identities = 36/94 (38%), Positives = 54/94 (57%), Gaps = 1/94 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +WMAPE + R Y + DV+SFG++LWE+ T G P+P + V+ F ++ +G R P Sbjct: 665 KWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGV-PVEELFKLLKEGHRMDKPS 723 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLERV 285 +C L +M CW A P RP F + L+R+ Sbjct: 724 NCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRI 757
>FGFR1_HUMAN (P11362) Basic fibroblast growth factor receptor 1 precursor (EC| 2.7.10.1) (FGFR-1) (bFGF-R) (Fms-like tyrosine kinase 2) (c-fgr) (CD331 antigen) Length = 822 Score = 71.2 bits (173), Expect = 2e-12 Identities = 36/94 (38%), Positives = 54/94 (57%), Gaps = 1/94 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +WMAPE + R Y + DV+SFG++LWE+ T G P+P + V+ F ++ +G R P Sbjct: 665 KWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGV-PVEELFKLLKEGHRMDKPS 723 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLERV 285 +C L +M CW A P RP F + L+R+ Sbjct: 724 NCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRI 757
>ILK1_HUMAN (Q13418) Integrin-linked protein kinase 1 (EC 2.7.11.1) (ILK-1) (59| kDa serine/threonine-protein kinase) (p59ILK) Length = 452 Score = 70.9 bits (172), Expect = 3e-12 Identities = 35/120 (29%), Positives = 68/120 (56%), Gaps = 4/120 (3%) Frame = -2 Query: 629 LTSEVARIEVKTEGMTP-ETGTYRWMAPEMIQHRPYN---QKVDVYSFGIVLWELITGTL 462 +T+ ++ +VK P W+APE +Q +P + + D++SF ++LWEL+T + Sbjct: 331 MTARISMADVKFSFQCPGRMYAPAWVAPEALQKKPEDTNRRSADMWSFAVLLWELVTREV 390 Query: 461 PFPNMTAVQAAFAVVNKGVRPAIPHDCLPALGEIMTRCWDANPDVRPPFTDVARMLERVE 282 PF +++ ++ V +G+RP IP P + ++M C + +P RP F + +LE+++ Sbjct: 391 PFADLSNMEIGMKVALEGLRPTIPPGISPHVCKLMKICMNEDPAKRPKFDMIVPILEKMQ 450
>EPHA7_MOUSE (Q61772) Ephrin type-A receptor 7 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Embryonic brain kinase) (EBK) (Developmental kinase 1) (MDK-1) Length = 998 Score = 70.9 bits (172), Expect = 3e-12 Identities = 38/119 (31%), Positives = 63/119 (52%), Gaps = 1/119 (0%) Frame = -2 Query: 638 SRLLTSEVARIEVKTEGMTPETGTYRWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTL 462 SR++ + + T G P RW APE IQ+R + DV+S+GIV+WE+++ G Sbjct: 780 SRVIEDDPEAVYTTTGGKIP----VRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGER 835 Query: 461 PFPNMTAVQAAFAVVNKGVRPAIPHDCLPALGEIMTRCWDANPDVRPPFTDVARMLERV 285 P+ +M+ Q + +G R P DC L ++M CW + RP F + +L+++ Sbjct: 836 PYWDMSN-QDVIKAIEEGYRLPAPMDCPAGLHQLMLDCWQKDRAERPKFEQIVGILDKM 893
>EPHA7_CHICK (O42422) Ephrin type-A receptor 7 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor CEPHA7) (Tyrosine-protein kinase receptor CEK11) Length = 993 Score = 70.9 bits (172), Expect = 3e-12 Identities = 38/119 (31%), Positives = 62/119 (52%), Gaps = 1/119 (0%) Frame = -2 Query: 638 SRLLTSEVARIEVKTEGMTPETGTYRWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTL 462 SR++ + + T G P RW APE IQ+R + DV+S+GIV+WE+++ G Sbjct: 775 SRVIEDDPEAVYTTTGGKIP----VRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGER 830 Query: 461 PFPNMTAVQAAFAVVNKGVRPAIPHDCLPALGEIMTRCWDANPDVRPPFTDVARMLERV 285 P+ +M+ Q + +G R P DC L ++M CW RP F + +L+++ Sbjct: 831 PYWDMSN-QDVIKAIEEGYRLPAPMDCPAGLHQLMLDCWQKERGERPKFEQIVGILDKM 888
>EPHA5_CHICK (P54755) Ephrin type-A receptor 5 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor CEK7) Length = 1013 Score = 70.9 bits (172), Expect = 3e-12 Identities = 36/94 (38%), Positives = 54/94 (57%), Gaps = 1/94 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 RW APE I R + DV+S+GIV+WE+++ G P+ MT Q V +G R P Sbjct: 819 RWTAPEAIAFRKFTSASDVWSYGIVMWEVMSYGERPYWEMTN-QDVIKAVEEGYRLPSPM 877 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLERV 285 DC AL ++M CW + + RP F ++ ML+++ Sbjct: 878 DCPAALYQLMLDCWQKDRNSRPKFDEIVSMLDKL 911
>INSRR_CAVPO (P14617) Insulin receptor-related protein precursor (EC 2.7.10.1)| (IRR) (IR-related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain] Length = 1300 Score = 70.9 bits (172), Expect = 3e-12 Identities = 34/93 (36%), Positives = 54/93 (58%), Gaps = 1/93 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 RWMAPE ++ + DV+SFG+VLWE++T P+ ++ Q V++ GV + Sbjct: 1157 RWMAPESLKDGIFTTHSDVWSFGVVLWEIVTLAEQPYQGLSNEQVLKFVMDGGVLEEL-E 1215 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLER 288 DC L E+M+ CW NP +RP FT + +++ Sbjct: 1216 DCPHQLQELMSSCWQQNPRLRPTFTQILNSIQK 1248
>VGFR3_HUMAN (P35916) Vascular endothelial growth factor receptor 3 precursor (EC| 2.7.10.1) (VEGFR-3) (Tyrosine-protein kinase receptor FLT4) Length = 1298 Score = 70.9 bits (172), Expect = 3e-12 Identities = 32/91 (35%), Positives = 50/91 (54%), Gaps = 1/91 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +WMAPE I + Y + DV+SFG++LWE+ + G P+P + + + G R P Sbjct: 1079 KWMAPESIFDKVYTTQSDVWSFGVLLWEIFSLGASPYPGVQINEEFCQRLRDGTRMRAPE 1138 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARML 294 PA+ IM CW +P RP F+++ +L Sbjct: 1139 LATPAIRRIMLNCWSGDPKARPAFSELVEIL 1169
>EPHA3_BRARE (O13146) Ephrin type-A receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ZEK1) (EPH-like kinase 1) Length = 981 Score = 70.9 bits (172), Expect = 3e-12 Identities = 36/94 (38%), Positives = 53/94 (56%), Gaps = 1/94 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 RW APE I +R + DV+S+GIV+WE+I+ G P+ M+ Q V++G R P Sbjct: 794 RWTAPEAITYRKFTSASDVWSYGIVMWEVISYGERPYWEMSN-QDVIKAVDEGYRLPAPM 852 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLERV 285 DC L ++M CW+ N RP F + L+R+ Sbjct: 853 DCPVVLHQLMLDCWEKNRSDRPKFGQIVNTLDRL 886
>PGFRA_HUMAN (P16234) Alpha platelet-derived growth factor receptor precursor (EC| 2.7.10.1) (PDGF-R-alpha) (CD140a antigen) Length = 1089 Score = 70.9 bits (172), Expect = 3e-12 Identities = 33/94 (35%), Positives = 52/94 (55%), Gaps = 1/94 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +WMAPE I Y DV+S+GI+LWE+ + G P+P M + + G R A P Sbjct: 860 KWMAPESIFDNLYTTLSDVWSYGILLWEIFSLGGTPYPGMMVDSTFYNKIKSGYRMAKPD 919 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLERV 285 + EIM +CW++ P+ RP F ++ ++E + Sbjct: 920 HATSEVYEIMVKCWNSEPEKRPSFYHLSEIVENL 953
>CEK3_CHICK (P18461) Tyrosine kinase receptor CEK3 precursor (EC 2.7.10.1)| Length = 823 Score = 70.9 bits (172), Expect = 3e-12 Identities = 35/94 (37%), Positives = 54/94 (57%), Gaps = 1/94 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +WMAPE + R Y + DV+SFG+++WE+ T G P+P + V+ F ++ +G R P Sbjct: 670 KWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGI-PVEELFKLLKEGHRMDKPA 728 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLERV 285 +C L +M CW A P RP F + L+R+ Sbjct: 729 NCTNELYMMMRDCWQAVPSQRPTFKQLVEDLDRI 762
>ILK_MOUSE (O55222) Integrin-linked protein kinase (EC 2.7.11.1)| Length = 452 Score = 70.5 bits (171), Expect = 4e-12 Identities = 34/120 (28%), Positives = 68/120 (56%), Gaps = 4/120 (3%) Frame = -2 Query: 629 LTSEVARIEVKTEGMTP-ETGTYRWMAPEMIQHRPYN---QKVDVYSFGIVLWELITGTL 462 +T+ ++ +VK P W+APE +Q +P + + D++SF ++LWEL+T + Sbjct: 331 MTARISMADVKFSFQCPGRMYAPAWVAPEALQKKPEDTNRRSADMWSFAVLLWELVTREV 390 Query: 461 PFPNMTAVQAAFAVVNKGVRPAIPHDCLPALGEIMTRCWDANPDVRPPFTDVARMLERVE 282 PF +++ ++ V +G+RP +P P + ++M C + +P RP F + +LE+++ Sbjct: 391 PFADLSNMEIGMKVALEGLRPTVPPGISPHVCKLMKICMNEDPAKRPKFDMIVPILEKMQ 450
>EPHA7_RAT (P54759) Ephrin type-A receptor 7 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) Length = 998 Score = 70.5 bits (171), Expect = 4e-12 Identities = 38/119 (31%), Positives = 62/119 (52%), Gaps = 1/119 (0%) Frame = -2 Query: 638 SRLLTSEVARIEVKTEGMTPETGTYRWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTL 462 SR++ + + T G P RW APE IQ+R + DV+S+GIV+WE+++ G Sbjct: 780 SRVIEDDPEAVYTTTGGKIP----VRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGER 835 Query: 461 PFPNMTAVQAAFAVVNKGVRPAIPHDCLPALGEIMTRCWDANPDVRPPFTDVARMLERV 285 P+ +M+ Q + +G R P DC L ++M CW RP F + +L+++ Sbjct: 836 PYWDMSN-QDVIKAIEEGYRLPAPMDCPAGLHQLMLDCWQKERAERPKFEQIVGILDKM 893
>EPHA7_HUMAN (Q15375) Ephrin type-A receptor 7 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Receptor protein-tyrosine kinase HEK11) Length = 998 Score = 70.5 bits (171), Expect = 4e-12 Identities = 38/119 (31%), Positives = 62/119 (52%), Gaps = 1/119 (0%) Frame = -2 Query: 638 SRLLTSEVARIEVKTEGMTPETGTYRWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTL 462 SR++ + + T G P RW APE IQ+R + DV+S+GIV+WE+++ G Sbjct: 780 SRVIEDDPEAVYTTTGGKIP----VRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGER 835 Query: 461 PFPNMTAVQAAFAVVNKGVRPAIPHDCLPALGEIMTRCWDANPDVRPPFTDVARMLERV 285 P+ +M+ Q + +G R P DC L ++M CW RP F + +L+++ Sbjct: 836 PYWDMSN-QDVIKAIEEGYRLPAPMDCPAGLHQLMLDCWQKERAERPKFEQIVGILDKM 893
>FGFR2_MOUSE (P21803) Fibroblast growth factor receptor 2 precursor (EC| 2.7.10.1) (FGFR-2) (Keratinocyte growth factor receptor) Length = 821 Score = 70.5 bits (171), Expect = 4e-12 Identities = 35/94 (37%), Positives = 54/94 (57%), Gaps = 1/94 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +WMAPE + R Y + DV+SFG+++WE+ T G P+P + V+ F ++ +G R P Sbjct: 668 KWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGI-PVEELFKLLKEGHRMDKPT 726 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLERV 285 +C L +M CW A P RP F + L+R+ Sbjct: 727 NCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRI 760
>FGFR2_HUMAN (P21802) Fibroblast growth factor receptor 2 precursor (EC| 2.7.10.1) (FGFR-2) (Keratinocyte growth factor receptor 2) (CD332 antigen) Length = 821 Score = 70.5 bits (171), Expect = 4e-12 Identities = 35/94 (37%), Positives = 54/94 (57%), Gaps = 1/94 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +WMAPE + R Y + DV+SFG+++WE+ T G P+P + V+ F ++ +G R P Sbjct: 668 KWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGI-PVEELFKLLKEGHRMDKPA 726 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLERV 285 +C L +M CW A P RP F + L+R+ Sbjct: 727 NCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRI 760
>RET_HUMAN (P07949) Proto-oncogene tyrosine-protein kinase receptor ret| precursor (EC 2.7.10.1) (C-ret) Length = 1114 Score = 70.5 bits (171), Expect = 4e-12 Identities = 33/97 (34%), Positives = 57/97 (58%), Gaps = 1/97 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +WMA E + Y + DV+SFG++LWE++T G P+P + + F ++ G R P Sbjct: 916 KWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPP-ERLFNLLKTGHRMERPD 974 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLERVEIE 276 +C + +M +CW PD RP F D+++ LE++ ++ Sbjct: 975 NCSEEMYRLMLQCWKQEPDKRPVFADISKDLEKMMVK 1011
>ROS_HUMAN (P08922) Proto-oncogene tyrosine-protein kinase ROS precursor (EC| 2.7.10.1) (c-ros-1) Length = 2347 Score = 70.5 bits (171), Expect = 4e-12 Identities = 40/116 (34%), Positives = 60/116 (51%), Gaps = 1/116 (0%) Frame = -2 Query: 593 EGMTPETGTYRWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVV 417 EG+ P RWMAPE + + + DV+SFGI++WE++T G P+P + + V Sbjct: 2120 EGLLP----VRWMAPESLMDGIFTTQSDVWSFGILIWEILTLGHQPYPAHSNLD-VLNYV 2174 Query: 416 NKGVRPAIPHDCLPALGEIMTRCWDANPDVRPPFTDVARMLERVEIEVLNNVRKAR 249 G R P +C L +MT+CW PD RP F + L+ LN++ + R Sbjct: 2175 QTGGRLEPPRNCPDDLWNLMTQCWAQEPDQRPTFHRIQNQLQLFRNFFLNSIYQCR 2230
>PGFRA_MOUSE (P26618) Alpha platelet-derived growth factor receptor precursor (EC| 2.7.10.1) (PDGF-R-alpha) Length = 1089 Score = 70.5 bits (171), Expect = 4e-12 Identities = 33/94 (35%), Positives = 52/94 (55%), Gaps = 1/94 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +WMAPE I Y DV+S+GI+LWE+ + G P+P M + + G R A P Sbjct: 860 KWMAPESIFDNLYTTLSDVWSYGILLWEIFSLGGTPYPGMMVDSTFYNKIKSGYRMAKPD 919 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLERV 285 + EIM +CW++ P+ RP F ++ ++E + Sbjct: 920 HATSEVYEIMVQCWNSEPEKRPSFYHLSEIVENL 953
>FGFR1_XENLA (P22182) Fibroblast growth factor receptor 1 precursor (EC| 2.7.10.1) (FGFR-1) Length = 812 Score = 70.5 bits (171), Expect = 4e-12 Identities = 35/94 (37%), Positives = 54/94 (57%), Gaps = 1/94 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +WMAPE + R Y + DV+SFG++LWE+ T G P+P + ++ F ++ +G R P Sbjct: 659 KWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGV-PMEELFKLLKEGHRMDKPT 717 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLERV 285 +C L +M CW A P RP F + L+R+ Sbjct: 718 NCTNELYMMMKDCWHAMPSQRPTFNQLVEDLDRI 751
>FGFR2_XENLA (Q03364) Fibroblast growth factor receptor 2 precursor (EC| 2.7.10.1) (FGFR-2) Length = 813 Score = 70.1 bits (170), Expect = 5e-12 Identities = 35/94 (37%), Positives = 54/94 (57%), Gaps = 1/94 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +WMAPE + R Y + DV+SFG+++WE+ T G P+P + V+ F ++ +G R P Sbjct: 658 KWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGI-PVEELFKLLKEGHRMDKPA 716 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLERV 285 +C L +M CW A P RP F + L+R+ Sbjct: 717 NCTNELYMMMRDCWHAIPSHRPTFKQLVEDLDRI 750
>PGFRA_RAT (P20786) Alpha platelet-derived growth factor receptor precursor (EC| 2.7.10.1) (PDGF-R-alpha) Length = 1088 Score = 70.1 bits (170), Expect = 5e-12 Identities = 32/94 (34%), Positives = 52/94 (55%), Gaps = 1/94 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +WMAPE I Y DV+S+G++LWE+ + G P+P M + + G R A P Sbjct: 859 KWMAPESIFDNLYTTLSDVWSYGVLLWEIFSLGGTPYPGMMVDSTFYNKIKSGYRMAKPD 918 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLERV 285 + EIM +CW++ P+ RP F ++ ++E + Sbjct: 919 HATSEVYEIMVQCWNSEPEKRPSFYHLSEIVENL 952
>SRC42_DROME (Q9V9J3) Tyrosine-protein kinase Src42A (EC 2.7.10.2) (Dsrc41)| Length = 517 Score = 69.7 bits (169), Expect = 7e-12 Identities = 38/92 (41%), Positives = 51/92 (55%), Gaps = 1/92 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +W APE + ++ K DV+SFGI+L EL+T G +P+P MT + V G R P Sbjct: 411 KWTAPEAANYSKFSIKSDVWSFGILLTELVTYGRIPYPGMTNAE-VLTQVEHGYRMPQPP 469 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLE 291 +C P L EIM CW +P RP F + LE Sbjct: 470 NCEPRLYEIMLECWHKDPMRRPTFETLQWKLE 501
>FES_FELCA (P14238) Proto-oncogene tyrosine-protein kinase FES/FPS (EC 2.7.10.2)| (C-FES) Length = 820 Score = 69.7 bits (169), Expect = 7e-12 Identities = 41/129 (31%), Positives = 66/129 (51%), Gaps = 6/129 (4%) Frame = -2 Query: 653 LVINRSRLLTSEVARIEVKTEGMTPETGTYR-----WMAPEMIQHRPYNQKVDVYSFGIV 489 LV ++ L S+ + +G+ +G R W APE + + Y+ + DV+SFGI+ Sbjct: 688 LVTEKNVLKISDFGMSREEADGIYAASGGLRQVPVKWTAPEALNYGRYSSESDVWSFGIL 747 Query: 488 LWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPHDCLPALGEIMTRCWDANPDVRPPFT 312 LWE + G P+PN++ Q V KG R P C A+ +M +CW P RP F+ Sbjct: 748 LWETFSLGASPYPNLSNQQTR-EFVEKGGRLPCPELCPDAVFRLMEQCWAYEPGQRPSFS 806 Query: 311 DVARMLERV 285 + + L+ + Sbjct: 807 AIYQELQSI 815
>FPS_AVISP (P00541) Tyrosine-protein kinase transforming protein Fps (EC| 2.7.10.2) Length = 533 Score = 69.7 bits (169), Expect = 7e-12 Identities = 39/119 (32%), Positives = 63/119 (52%), Gaps = 6/119 (5%) Frame = -2 Query: 653 LVINRSRLLTSEVARIEVKTEGMTPETG-----TYRWMAPEMIQHRPYNQKVDVYSFGIV 489 LV ++ L S+ + +G+ TG +W APE + + Y+ + DV+SFGI+ Sbjct: 401 LVTEKNTLKISDFGMSRQEEDGVYASTGGMKQIPVKWTAPEALNYGRYSSESDVWSFGIL 460 Query: 488 LWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPHDCLPALGEIMTRCWDANPDVRPPF 315 LWE + G +P+ N++ Q A + +GVR P C + +M RCW+ +P RP F Sbjct: 461 LWEAFSLGAVPYANLSNQQTREA-IEQGVRLEPPEQCPEDVYRLMQRCWEYDPRRRPSF 518
>TIE1_BOVIN (Q06805) Tyrosine-protein kinase receptor Tie-1 precursor (EC| 2.7.10.1) Length = 1136 Score = 69.7 bits (169), Expect = 7e-12 Identities = 38/106 (35%), Positives = 57/106 (53%), Gaps = 1/106 (0%) Frame = -2 Query: 599 KTEGMTPETGTYRWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFA 423 KT G P RWMA E + + Y K DV+SFG++LWE+++ G P+ MT + + Sbjct: 1008 KTMGRLP----VRWMAIESLNYSVYTTKSDVWSFGVLLWEIVSLGGTPYCGMTCAE-LYE 1062 Query: 422 VVNKGVRPAIPHDCLPALGEIMTRCWDANPDVRPPFTDVARMLERV 285 + + R P +C + E+M +CW P RPPF +A L R+ Sbjct: 1063 KLPQAYRMEQPRNCDDEVYELMRQCWRDRPYERPPFAQIALQLGRM 1108
>PGFRA_XENLA (P26619) Alpha platelet-derived growth factor receptor precursor (EC| 2.7.10.1) (PDGF-R-alpha) Length = 1087 Score = 69.7 bits (169), Expect = 7e-12 Identities = 33/92 (35%), Positives = 51/92 (55%), Gaps = 1/92 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +WMAPE I Y DV+SFGI+LWE+ + G P+P M + + G R A P Sbjct: 860 KWMAPESIFDNLYTTLSDVWSFGILLWEIFSLGGTPYPGMIVDSTFYNKIKSGYRMAKPD 919 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLE 291 + +IM +CW++ P+ RP F ++ ++E Sbjct: 920 HATHEVYDIMVKCWNSEPEKRPSFRHLSDIVE 951
>FGFR1_RAT (Q04589) Basic fibroblast growth factor receptor 1 precursor (EC| 2.7.10.1) (FGFR-1) (bFGF-R) (MFR) Length = 822 Score = 69.7 bits (169), Expect = 7e-12 Identities = 36/94 (38%), Positives = 54/94 (57%), Gaps = 1/94 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +WMAPE + R Y + DV+SFG++LWE+ T G P P + V+ F ++ +G R P Sbjct: 665 KWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPNPGV-PVEELFKLLKEGHRMDKPS 723 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLERV 285 +C L +M CW+A P RP F + L+R+ Sbjct: 724 NCTNELYMMMRDCWNAVPSQRPTFKQLVEDLDRI 757
>FES_HUMAN (P07332) Proto-oncogene tyrosine-protein kinase Fes/Fps (EC 2.7.10.2)| (C-Fes) Length = 822 Score = 69.7 bits (169), Expect = 7e-12 Identities = 41/129 (31%), Positives = 66/129 (51%), Gaps = 6/129 (4%) Frame = -2 Query: 653 LVINRSRLLTSEVARIEVKTEGMTPETGTYR-----WMAPEMIQHRPYNQKVDVYSFGIV 489 LV ++ L S+ + +G+ +G R W APE + + Y+ + DV+SFGI+ Sbjct: 690 LVTEKNVLKISDFGMSREEADGVYAASGGSRQVPVKWTAPEALNYGRYSSESDVWSFGIL 749 Query: 488 LWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPHDCLPALGEIMTRCWDANPDVRPPFT 312 LWE + G P+PN++ Q V KG R P C A+ +M +CW P RP F+ Sbjct: 750 LWETFSLGASPYPNLSNQQTR-EFVEKGGRLPCPELCPDAVFRLMEQCWAYEPGQRPSFS 808 Query: 311 DVARMLERV 285 + + L+ + Sbjct: 809 TIYQELQSI 817
>PTK6_MOUSE (Q64434) Tyrosine-protein kinase 6 (EC 2.7.10.2) (SRC-related| intestinal kinase) Length = 451 Score = 69.3 bits (168), Expect = 9e-12 Identities = 34/92 (36%), Positives = 53/92 (57%), Gaps = 1/92 (1%) Frame = -2 Query: 566 YRWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIP 390 Y+W APE + Y+ K DV+SFG++L E+ + G +P+P M+ + F V+ G R P Sbjct: 351 YKWTAPEALSRGHYSIKSDVWSFGVLLHEIFSRGQMPYPGMSNHET-FLRVDAGYRMPCP 409 Query: 389 HDCLPALGEIMTRCWDANPDVRPPFTDVARML 294 +C P + ++M CW +P RP F D+ L Sbjct: 410 LECPPNIHKLMLSCWSRDPKQRPCFKDLCEKL 441
>FYN_XIPHE (P27446) Proto-oncogene tyrosine-protein kinase FYN (EC 2.7.10.2)| (P59-FYN) Length = 536 Score = 69.3 bits (168), Expect = 9e-12 Identities = 36/92 (39%), Positives = 52/92 (56%), Gaps = 1/92 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +W APE + + K DV+SFGI+L EL+T G +P+P M + V +G R P Sbjct: 430 KWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNN-REVLEQVERGYRMPCPQ 488 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLE 291 DC +L E+M +CW +P+ RP F + LE Sbjct: 489 DCPASLHELMLQCWKKDPEERPTFEYLQAFLE 520
>FPS_FUJSV (P00530) Tyrosine-protein kinase transforming protein FPS (EC| 2.7.10.2) Length = 873 Score = 69.3 bits (168), Expect = 9e-12 Identities = 39/119 (32%), Positives = 63/119 (52%), Gaps = 6/119 (5%) Frame = -2 Query: 653 LVINRSRLLTSEVARIEVKTEGMTPETG-----TYRWMAPEMIQHRPYNQKVDVYSFGIV 489 LV ++ L S+ + +G+ TG +W APE + + Y+ + DV+SFGI+ Sbjct: 741 LVTEKNTLKISDFGMSRQEEDGVYASTGGMKQIPVKWTAPEALNYGWYSSESDVWSFGIL 800 Query: 488 LWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPHDCLPALGEIMTRCWDANPDVRPPF 315 LWE + G +P+ N++ Q A + +GVR P C + +M RCW+ +P RP F Sbjct: 801 LWEAFSLGAVPYANLSNQQTREA-IEQGVRLEPPEQCPEDVYRLMQRCWEYDPHRRPSF 858
>ABL1_CAEEL (P03949) Tyrosine-protein kinase abl-1 (EC 2.7.10.2)| Length = 1224 Score = 69.3 bits (168), Expect = 9e-12 Identities = 39/138 (28%), Positives = 70/138 (50%), Gaps = 2/138 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +W APE + ++ K DV++FG++LWE+ T G P+P + + + ++ G R P Sbjct: 473 KWTAPEGLAFNTFSSKSDVWAFGVLLWEIATYGMAPYPGV-ELSNVYGLLENGFRMDGPQ 531 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLER-VEIEVLNNVRKARFRCCISQPMTLD* 210 C P++ +M +CW+ +P RP F D+ LE + LN+ + + + + + D Sbjct: 532 GCPPSVYRLMLQCWNWSPSDRPRFRDIHFNLENLISSNSLNDEVQKQLKKNNDKKLESDK 591 Query: 209 GRQNSKEKKAIWREVKSH 156 R N +E+ SH Sbjct: 592 RRSNVRERSDSKSRHSSH 609
>EPA4A_BRARE (O13148) Ephrin type-A receptor 4a (EC 2.7.10.1) (Tyrosine-protein| kinase receptor ZEK2) (EPH-like kinase 2) (Fragment) Length = 292 Score = 68.9 bits (167), Expect = 1e-11 Identities = 37/107 (34%), Positives = 58/107 (54%), Gaps = 10/107 (9%) Frame = -2 Query: 575 TGTY---------RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAF 426 TGTY RW APE I +R + DV+S+GIV+WE+++ G P+ +M+ Q Sbjct: 159 TGTYQSQGGKIPIRWTAPEAITYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSN-QDVI 217 Query: 425 AVVNKGVRPAIPHDCLPALGEIMTRCWDANPDVRPPFTDVARMLERV 285 + +G R P DC +L ++M CW RP F+ + ML+++ Sbjct: 218 KAIEEGYRLPPPMDCPVSLHQLMLDCWQKERAERPKFSQIVNMLDKL 264
>PTK6_HUMAN (Q13882) Tyrosine-protein kinase 6 (EC 2.7.10.2) (Breast tumor| kinase) (Tyrosine-protein kinase BRK) Length = 451 Score = 68.9 bits (167), Expect = 1e-11 Identities = 34/85 (40%), Positives = 52/85 (61%), Gaps = 1/85 (1%) Frame = -2 Query: 566 YRWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIP 390 Y+W APE + Y+ K DV+SFGI+L E+ + G +P+P M+ AF V+ G R P Sbjct: 351 YKWTAPEALSRGHYSTKSDVWSFGILLHEMFSRGQVPYPGMSN-HEAFLRVDAGYRMPCP 409 Query: 389 HDCLPALGEIMTRCWDANPDVRPPF 315 +C P++ ++M CW +P+ RP F Sbjct: 410 LECPPSVHKLMLTCWCRDPEQRPCF 434
>FES_FSVGA (P00542) Tyrosine-protein kinase transforming protein Fes (EC| 2.7.10.2) Length = 609 Score = 68.9 bits (167), Expect = 1e-11 Identities = 41/129 (31%), Positives = 65/129 (50%), Gaps = 6/129 (4%) Frame = -2 Query: 653 LVINRSRLLTSEVARIEVKTEGMTPETGTYR-----WMAPEMIQHRPYNQKVDVYSFGIV 489 LV ++ L S+ +G+ +G R W APE + + Y+ + DV+SFGI+ Sbjct: 477 LVTEKNVLKISDFGMSREAADGIYAASGGLRQVPVKWTAPEALNYGRYSSESDVWSFGIL 536 Query: 488 LWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPHDCLPALGEIMTRCWDANPDVRPPFT 312 LWE + G P+PN++ Q V KG R P C A+ +M +CW P RP F+ Sbjct: 537 LWETFSLGASPYPNLSNQQTR-EFVEKGGRLPCPELCPDAVFRLMEQCWAYEPGQRPSFS 595 Query: 311 DVARMLERV 285 + + L+ + Sbjct: 596 AIYQELQSI 604
>EPHA6_HUMAN (Q9UF33) Ephrin type-A receptor 6 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2) Length = 1035 Score = 68.9 bits (167), Expect = 1e-11 Identities = 38/119 (31%), Positives = 61/119 (51%), Gaps = 1/119 (0%) Frame = -2 Query: 638 SRLLTSEVARIEVKTEGMTPETGTYRWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTL 462 SR+L + T G P RW APE I +R ++ D +S+GIV+WE+++ G Sbjct: 819 SRVLEDDPEAAYTTTGGKIP----IRWTAPEAIAYRKFSSASDAWSYGIVMWEVMSYGER 874 Query: 461 PFPNMTAVQAAFAVVNKGVRPAIPHDCLPALGEIMTRCWDANPDVRPPFTDVARMLERV 285 P+ M+ Q + +G R P C +L ++M CW + RP FTD+ L+++ Sbjct: 875 PYWEMSN-QDVILSIEEGYRLPAPMGCPASLHQLMLHCWQKERNHRPKFTDIVSFLDKL 932
>FGFR2_DROME (Q09147) Fibroblast growth factor receptor homolog 2 precursor (EC| 2.7.10.1) (Protein breathless) (dFGF-R1) Length = 1052 Score = 68.9 bits (167), Expect = 1e-11 Identities = 33/115 (28%), Positives = 62/115 (53%), Gaps = 1/115 (0%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +WMAPE +Q + Y+ + DV+S+G++LWE++T G P+P++ + + ++ + G R P Sbjct: 906 KWMAPESLQEKKYDSQSDVWSYGVLLWEIMTYGDQPYPHILSAEELYSYLITGQRMEKPA 965 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLERVEIEVLNNVRKARFRCCISQPM 222 C + +M +CW RP F ++ + + + +N A +S PM Sbjct: 966 KCSLNIYVVMRQCWHFESCARPTFAELVESFDGILQQASSNPNDAYLD--LSMPM 1018
>FES_MOUSE (P16879) Proto-oncogene tyrosine-protein kinase Fes/Fps (EC 2.7.10.2)| (C-Fes) Length = 820 Score = 68.9 bits (167), Expect = 1e-11 Identities = 35/94 (37%), Positives = 52/94 (55%), Gaps = 1/94 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +W APE + + Y+ + DV+SFGI+LWE + G P+PN+T Q V KG R P Sbjct: 723 KWTAPEALNYGRYSSESDVWSFGILLWETFSLGASPYPNLTNQQTR-EFVEKGHRLPCPE 781 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLERV 285 C A+ +M +CW P RP F+ + + L + Sbjct: 782 LCPDAVFRLMEQCWAYEPGQRPSFSIICQELHSI 815
>INSRR_HUMAN (P14616) Insulin receptor-related protein precursor (EC 2.7.10.1)| (IRR) (IR-related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain] Length = 1297 Score = 68.9 bits (167), Expect = 1e-11 Identities = 38/107 (35%), Positives = 60/107 (56%), Gaps = 1/107 (0%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 RWMAPE ++ + DV+SFG+VLWE++T P+ ++ Q V++ GV + Sbjct: 1157 RWMAPESLKDGIFTTHSDVWSFGVVLWEIVTLAEQPYQGLSNEQVLKFVMDGGVLEEL-E 1215 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLERVEIEVLNNVRKARF 246 C L E+M+RCW NP +RP FT + L+ ++ E+ + R F Sbjct: 1216 GCPLQLQELMSRCWQPNPRLRPSFTHI---LDSIQEELRPSFRLLSF 1259
>SEA_AVIET (P23049) Tyrosine-protein kinase transforming protein SEA (EC| 2.7.10.2) Length = 370 Score = 68.6 bits (166), Expect = 2e-11 Identities = 36/94 (38%), Positives = 53/94 (56%), Gaps = 1/94 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 RWMA E +Q + + K DV+SFG+++WEL+T G P+P + A ++ +G R P Sbjct: 230 RWMALESLQTQKFTTKSDVWSFGVLMWELLTRGASPYPEVDPYDMARYLL-RGRRLPQPQ 288 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLERV 285 C L +M CW P+ RP F+ + LERV Sbjct: 289 PCPDTLYGVMLSCWAPTPEERPSFSGLVCELERV 322
>YES_XIPHE (P27447) Tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes)| Length = 543 Score = 68.6 bits (166), Expect = 2e-11 Identities = 36/92 (39%), Positives = 51/92 (55%), Gaps = 1/92 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +W APE + + K DV+SFGI+L EL+T G +P+P M + V++G R P Sbjct: 437 KWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMVN-REVLEQVDRGYRMPCPQ 495 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLE 291 C +L E+M +CW PD RP F + LE Sbjct: 496 GCPESLHEMMRQCWKKEPDERPTFEYIQSFLE 527
>INSR_DROME (P09208) Insulin-like receptor precursor (EC 2.7.10.1) (DIR) (DInr)| (dIRH) [Contains: Insulin-like receptor alpha subunit; Insulin-like receptor beta 1 subunit; Insulin-like receptor beta 2 subunit] Length = 2144 Score = 68.6 bits (166), Expect = 2e-11 Identities = 37/103 (35%), Positives = 54/103 (52%), Gaps = 1/103 (0%) Frame = -2 Query: 596 TEGMTPETGTYRWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAV 420 T+G+ P RWM PE ++ Y+ DV+SFG+VLWE+ T P+ ++ Q V Sbjct: 1554 TKGLLP----VRWMPPESLRDGVYSSASDVFSFGVVLWEMATLAAQPYQGLSNEQVLRYV 1609 Query: 419 VNKGVRPAIPHDCLPALGEIMTRCWDANPDVRPPFTDVARMLE 291 ++ GV P +C L ++M RCW RP F D+ LE Sbjct: 1610 IDGGVMER-PENCPDFLHKLMQRCWHHRSSARPSFLDIIAYLE 1651
>TXK_HUMAN (P42681) Tyrosine-protein kinase TXK (EC 2.7.10.2)| Length = 527 Score = 68.6 bits (166), Expect = 2e-11 Identities = 32/94 (34%), Positives = 54/94 (57%), Gaps = 1/94 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +W PE+ Y+ K DV+SFG+++WE+ T G +PF N + +Q A +++G R PH Sbjct: 431 KWSPPEVFLFNKYSSKSDVWSFGVLMWEVFTEGKMPFENKSNLQVVEA-ISEGFRLYRPH 489 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLERV 285 ++ E+M CW P+ RP F ++ R + + Sbjct: 490 LAPMSIYEVMYSCWHEKPEGRPTFAELLRAVTEI 523
>EPHA8_RAT (P29321) Ephrin type-A receptor 8 (EC 2.7.10.1) (Tyrosine-protein| kinase receptor EEK) (EPH- and ELK-related kinase) (Fragment) Length = 372 Score = 68.6 bits (166), Expect = 2e-11 Identities = 37/92 (40%), Positives = 52/92 (56%), Gaps = 1/92 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 RW APE I R ++ DV+SFG+V+WE++ G P+ NMT Q + V +G R P Sbjct: 170 RWTAPEAIAFRTFSSASDVWSFGVVMWEVLAYGERPYWNMTN-QDVISSVEEGYRLPAPM 228 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLE 291 C AL ++M CW + RP F+ V +LE Sbjct: 229 GCPRALHQLMLDCWHKDRAQRPRFSHVVSVLE 260
>ABL2_HUMAN (P42684) Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine| leukemia viral oncogene homolog 2) (Tyrosine kinase ARG) Length = 1182 Score = 68.2 bits (165), Expect = 2e-11 Identities = 32/92 (34%), Positives = 52/92 (56%), Gaps = 1/92 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +W APE + + ++ K DV++FG++LWE+ T G P+P + Q + ++ KG R P Sbjct: 450 KWTAPESLAYNTFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQ-VYDLLEKGYRMEQPE 508 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLE 291 C P + E+M CW +P RP F + + E Sbjct: 509 GCPPKVYELMRACWKWSPADRPSFAETHQAFE 540
>FYN_HUMAN (P06241) Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2)| (p59-Fyn) (Protooncogene Syn) (SLK) Length = 536 Score = 68.2 bits (165), Expect = 2e-11 Identities = 36/92 (39%), Positives = 51/92 (55%), Gaps = 1/92 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +W APE + + K DV+SFGI+L EL+T G +P+P M + V +G R P Sbjct: 430 KWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNN-REVLEQVERGYRMPCPQ 488 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLE 291 DC +L E+M CW +P+ RP F + LE Sbjct: 489 DCPISLHELMIHCWKKDPEERPTFEYLQSFLE 520
>LCK_CHICK (P42683) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (Protein-tyrosine kinase C-TKL) (p56tk1) Length = 507 Score = 68.2 bits (165), Expect = 2e-11 Identities = 35/92 (38%), Positives = 53/92 (57%), Gaps = 1/92 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +W APE I + + K DV+SFGI+L E++T G +P+P MT + + +G R P Sbjct: 403 KWTAPEAINYGTFTIKSDVWSFGILLTEIVTYGRIPYPGMTNPE-VIQNLERGYRMPQPD 461 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLE 291 +C L E+M +CW P+ RP F + +LE Sbjct: 462 NCPQELYELMMQCWKEQPEERPTFEYMKSVLE 493
>SPK1_DUGTI (P42687) Tyrosine-protein kinase SPK-1 (EC 2.7.10.2)| Length = 497 Score = 68.2 bits (165), Expect = 2e-11 Identities = 36/108 (33%), Positives = 61/108 (56%), Gaps = 7/108 (6%) Frame = -2 Query: 566 YRWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIP 390 Y+W APE + + + K DV+S+GIV++E++T + P+P++ A + V+KG R P Sbjct: 383 YKWTAPEAAKSKVFTSKSDVWSYGIVMFEILTWASSPYPDIPA-KEVIEKVSKGYRMPNP 441 Query: 389 HD------CLPALGEIMTRCWDANPDVRPPFTDVARMLERVEIEVLNN 264 C + +IM CWDANP+ RP F + ++ + ++ L N Sbjct: 442 EKFITGVCCPDEIYKIMIWCWDANPEKRPTFLVLQEKMDLLIVDTLTN 489
>FES_FSVST (P00543) Tyrosine-protein kinase transforming protein Fes (EC| 2.7.10.2) Length = 477 Score = 68.2 bits (165), Expect = 2e-11 Identities = 41/129 (31%), Positives = 65/129 (50%), Gaps = 6/129 (4%) Frame = -2 Query: 653 LVINRSRLLTSEVARIEVKTEGMTPETGTYR-----WMAPEMIQHRPYNQKVDVYSFGIV 489 LV ++ L S+ + +G+ +G R W APE + + Y+ + DV+SFGI+ Sbjct: 345 LVTEKNVLKISDFGMSREEADGVYAASGGLRLVPVKWTAPEALNYGRYSSESDVWSFGIL 404 Query: 488 LWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPHDCLPALGEIMTRCWDANPDVRPPFT 312 LWE + G P+PN++ Q V KG R P C A+ +M +CW P RP F+ Sbjct: 405 LWETFSLGASPYPNLSNQQTR-EFVEKGGRLPCPELCPDAVFRLMEQCWAYEPGQRPSFS 463 Query: 311 DVARMLERV 285 + L+ + Sbjct: 464 AFYQELQSI 472
>ILK2_HUMAN (P57043) Integrin-linked protein kinase 2 (EC 2.7.11.1) (ILK-2)| Length = 452 Score = 67.8 bits (164), Expect = 3e-11 Identities = 34/120 (28%), Positives = 67/120 (55%), Gaps = 4/120 (3%) Frame = -2 Query: 629 LTSEVARIEVKTEGMTP-ETGTYRWMAPEMIQHRPYN---QKVDVYSFGIVLWELITGTL 462 +T+ ++ +VK P W+APE +Q +P + + D++SF ++LWEL+T + Sbjct: 331 MTARISMADVKFSFQCPGRMYAPAWVAPEALQKKPEDTNRRSADMWSFAVLLWELVTREV 390 Query: 461 PFPNMTAVQAAFAVVNKGVRPAIPHDCLPALGEIMTRCWDANPDVRPPFTDVARMLERVE 282 PF +++ ++ V +G+RP IP P + ++M C + +P R F + +LE+++ Sbjct: 391 PFADLSNMEIGMKVALEGLRPTIPPGISPHVCKLMKICMNEDPAKRSKFDMIVPILEKMQ 450
>YES_AVISY (P00527) Tyrosine-protein kinase transforming protein YES (EC| 2.7.10.2) (Fragment) Length = 528 Score = 67.8 bits (164), Expect = 3e-11 Identities = 36/92 (39%), Positives = 50/92 (54%), Gaps = 1/92 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +W APE + + K DV+SFGI+L EL+T G +P+P M + V +G R P Sbjct: 427 KWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMVN-REVLEQVERGYRMPCPQ 485 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLE 291 C +L E+M CW +PD RP F + LE Sbjct: 486 GCPESLHELMKLCWKKDPDERPTFEYIQSFLE 517
>YES_CHICK (P09324) Tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes)| Length = 540 Score = 67.8 bits (164), Expect = 3e-11 Identities = 36/92 (39%), Positives = 50/92 (54%), Gaps = 1/92 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +W APE + + K DV+SFGI+L EL+T G +P+P M + V +G R P Sbjct: 434 KWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMVN-REVLEQVERGYRMPCPQ 492 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLE 291 C +L E+M CW +PD RP F + LE Sbjct: 493 GCPESLHELMKLCWKKDPDERPTFEYIQSFLE 524
>BCK1_YEAST (Q01389) Serine/threonine-protein kinase BCK1/SLK1/SSP31 (EC| 2.7.11.1) Length = 1478 Score = 67.8 bits (164), Expect = 3e-11 Identities = 36/102 (35%), Positives = 55/102 (53%), Gaps = 13/102 (12%) Frame = -2 Query: 572 GTYRWMAPEMIQHRP-YNQKVDVYSFGIVLWELITGTLPFPNMTAVQAAFAVVNKGVRPA 396 GT WMAPEM+ + Y+ KVD++S G ++ E+ G P+ N+ V A F + P Sbjct: 1341 GTVFWMAPEMVDTKQGYSAKVDIWSLGCIVLEMFAGKRPWSNLEVVAAMFKIGKSKSAPP 1400 Query: 395 IPHDCLPALGEI----MTRCWDANPDVRP--------PFTDV 306 IP D LP + +I + C++ NP+ RP PF++V Sbjct: 1401 IPEDTLPLISQIGRNFLDACFEINPEKRPTANELLSHPFSEV 1442
>FYN_XENLA (P13406) Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2)| (p59-Fyn) Length = 536 Score = 67.8 bits (164), Expect = 3e-11 Identities = 36/92 (39%), Positives = 51/92 (55%), Gaps = 1/92 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +W APE + + K DV+SFGI+L EL+T G +P+P M + V +G R P Sbjct: 430 KWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNN-REVLEQVERGYRMPCPQ 488 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLE 291 DC +L E+M CW +P+ RP F + LE Sbjct: 489 DCPISLHELMLNCWKKDPEERPTFEYLQGFLE 520
>KSYK_PIG (Q00655) Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine| kinase) [Contains: 72 kDa tyrosine-protein kinase SYK; 40 kDa tyrosine-protein kinase SYK] Length = 628 Score = 67.8 bits (164), Expect = 3e-11 Identities = 39/125 (31%), Positives = 64/125 (51%), Gaps = 1/125 (0%) Frame = -2 Query: 638 SRLLTSEVARIEVKTEGMTPETGTYRWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTL 462 S+ L ++ + +T G P +W APE I + ++ K DV+SFG+++WE + G Sbjct: 509 SKALRADENYYKAQTHGKWP----VKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQK 564 Query: 461 PFPNMTAVQAAFAVVNKGVRPAIPHDCLPALGEIMTRCWDANPDVRPPFTDVARMLERVE 282 P+ M + + A++ KG R P C + E+MT CW + + RP F V L Sbjct: 565 PYRGMKGSEVS-AMLEKGERMGCPPGCPREMYELMTLCWTYDVENRPGFVAVELRLRNYY 623 Query: 281 IEVLN 267 +V+N Sbjct: 624 YDVVN 628
>EPA4B_XENLA (Q91694) Ephrin type-A receptor 4-B precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor PAG) (Pagliaccio) Length = 985 Score = 67.8 bits (164), Expect = 3e-11 Identities = 34/94 (36%), Positives = 54/94 (57%), Gaps = 1/94 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 RW APE I +R + DV+S+GIV+WE+++ G P+ +M+ Q + +G R P Sbjct: 788 RWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSN-QDVIKAIEEGYRLPPPM 846 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLERV 285 DC AL ++M CW + RP F + ML+++ Sbjct: 847 DCPIALHQLMLDCWQKDRSDRPKFGQIVSMLDKL 880
>FYN_MOUSE (P39688) Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2)| (p59-Fyn) Length = 533 Score = 67.8 bits (164), Expect = 3e-11 Identities = 36/92 (39%), Positives = 51/92 (55%), Gaps = 1/92 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +W APE + + K DV+SFGI+L EL+T G +P+P M + V +G R P Sbjct: 427 KWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNN-REVLEQVERGYRMPCPQ 485 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLE 291 DC +L E+M CW +P+ RP F + LE Sbjct: 486 DCPISLHELMIHCWKKDPEERPTFEYLQGFLE 517
>FYN_CHICK (Q05876) Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2)| (p59-Fyn) Length = 533 Score = 67.8 bits (164), Expect = 3e-11 Identities = 36/92 (39%), Positives = 51/92 (55%), Gaps = 1/92 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +W APE + + K DV+SFGI+L EL+T G +P+P M + V +G R P Sbjct: 427 KWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNN-REVLEQVERGYRMPCPQ 485 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLE 291 DC +L E+M CW +P+ RP F + LE Sbjct: 486 DCPISLHELMIHCWKKDPEERPTFEYLQGFLE 517
>EPHB2_MOUSE (P54763) Ephrin type-B receptor 2 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EPH-3) (Neural kinase) (Nuk receptor tyrosine kinase) (SEK-3) Length = 994 Score = 67.8 bits (164), Expect = 3e-11 Identities = 34/94 (36%), Positives = 54/94 (57%), Gaps = 1/94 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 RW APE IQ+R + DV+S+GIV+WE+++ G P+ +MT Q + + R P Sbjct: 799 RWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTN-QDVINAIEQDYRLPPPM 857 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLERV 285 DC AL ++M CW + + RP F + L+++ Sbjct: 858 DCPSALHQLMLDCWQKDRNHRPKFGQIVNTLDKM 891
>EPHA4_MOUSE (Q03137) Ephrin type-A receptor 4 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor SEK) (MPK-3) Length = 986 Score = 67.8 bits (164), Expect = 3e-11 Identities = 34/94 (36%), Positives = 53/94 (56%), Gaps = 1/94 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 RW APE I +R + DV+S+GIV+WE+++ G P+ +M+ Q + +G R P Sbjct: 789 RWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSN-QDVIKAIEEGYRLPPPM 847 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLERV 285 DC AL ++M CW RP F + ML+++ Sbjct: 848 DCPIALHQLMLDCWQKERSDRPKFGQIVNMLDKL 881
>EPHA4_HUMAN (P54764) Ephrin type-A receptor 4 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor SEK) (Receptor protein-tyrosine kinase HEK8) Length = 986 Score = 67.8 bits (164), Expect = 3e-11 Identities = 34/94 (36%), Positives = 53/94 (56%), Gaps = 1/94 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 RW APE I +R + DV+S+GIV+WE+++ G P+ +M+ Q + +G R P Sbjct: 789 RWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSN-QDVIKAIEEGYRLPPPM 847 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLERV 285 DC AL ++M CW RP F + ML+++ Sbjct: 848 DCPIALHQLMLDCWQKERSDRPKFGQIVNMLDKL 881
>EPHA4_CHICK (Q07496) Ephrin type-A receptor 4 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor CEK8) Length = 986 Score = 67.8 bits (164), Expect = 3e-11 Identities = 34/94 (36%), Positives = 53/94 (56%), Gaps = 1/94 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 RW APE I +R + DV+S+GIV+WE+++ G P+ +M+ Q + +G R P Sbjct: 789 RWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSN-QDVIKAIEEGYRLPPPM 847 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLERV 285 DC AL ++M CW RP F + ML+++ Sbjct: 848 DCPIALHQLMLDCWQKERSDRPKFGQIVNMLDKL 881
>EPHB2_HUMAN (P29323) Ephrin type-B receptor 2 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EPH-3) (DRT) (Receptor protein-tyrosine kinase HEK5) (ERK) (NY-REN-47 antigen) Length = 1055 Score = 67.8 bits (164), Expect = 3e-11 Identities = 34/94 (36%), Positives = 54/94 (57%), Gaps = 1/94 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 RW APE IQ+R + DV+S+GIV+WE+++ G P+ +MT Q + + R P Sbjct: 791 RWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTN-QDVINAIEQDYRLPPPM 849 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLERV 285 DC AL ++M CW + + RP F + L+++ Sbjct: 850 DCPSALHQLMLDCWQKDRNHRPKFGQIVNTLDKM 883
>MET_MOUSE (P16056) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1379 Score = 67.8 bits (164), Expect = 3e-11 Identities = 32/94 (34%), Positives = 55/94 (58%), Gaps = 1/94 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +WMA E +Q + + K DV+SFG++LWEL+T G P+P++ ++ +G R P Sbjct: 1246 KWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITIYLL-QGRRLLQPE 1304 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLERV 285 C AL E+M +CW ++RP F+++ + + Sbjct: 1305 YCPDALYEVMLKCWHPKAEMRPSFSELVSRISSI 1338
>FAK1_XENLA (Q91738) Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK)| Length = 1068 Score = 67.8 bits (164), Expect = 3e-11 Identities = 37/107 (34%), Positives = 55/107 (51%), Gaps = 2/107 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +WMAPE I R + DV+ FG+ +WE++ G PF + + N G R +P Sbjct: 600 KWMAPESINFRRFTSASDVWMFGVCMWEILMYGVKPFQGVKNNDVIGRIEN-GERLPMPP 658 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLERV-EIEVLNNVRKAR 249 +C P L +MT+CW +P RP FT++ L + E E L + R Sbjct: 659 NCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEEEKLQQEERMR 705
>FAK1_CHICK (Q00944) Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK)| Length = 1053 Score = 67.8 bits (164), Expect = 3e-11 Identities = 37/107 (34%), Positives = 55/107 (51%), Gaps = 2/107 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +WMAPE I R + DV+ FG+ +WE++ G PF + + N G R +P Sbjct: 587 KWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIEN-GERLPMPP 645 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLERV-EIEVLNNVRKAR 249 +C P L +MT+CW +P RP FT++ L + E E L + R Sbjct: 646 NCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEEEKLQQEERMR 692
>ABL1_HUMAN (P00519) Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2)| (p150) (c-ABL) (Abelson murine leukemia viral oncogene homolog 1) Length = 1130 Score = 67.4 bits (163), Expect = 4e-11 Identities = 34/106 (32%), Positives = 57/106 (53%), Gaps = 3/106 (2%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +W APE + + ++ K DV++FG++LWE+ T G P+P + Q + ++ K R P Sbjct: 404 KWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQ-VYELLEKDYRMERPE 462 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLERV--EIEVLNNVRK 255 C + E+M CW NP RP F ++ + E + E + + V K Sbjct: 463 GCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQESSISDEVEK 508
>CSK_MOUSE (P41241) Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase)| (Protein-tyrosine kinase MPK-2) (p50CSK) Length = 450 Score = 67.4 bits (163), Expect = 4e-11 Identities = 36/114 (31%), Positives = 61/114 (53%), Gaps = 3/114 (2%) Frame = -2 Query: 599 KTEGMTPETGTY--RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAA 429 K T +TG +W APE ++ + ++ K DV+SFGI+LWE+ + G +P+P + ++ Sbjct: 337 KEASSTQDTGKLPVKWTAPEALREKKFSTKSDVWSFGILLWEIYSFGRVPYPRI-PLKDV 395 Query: 428 FAVVNKGVRPAIPHDCLPALGEIMTRCWDANPDVRPPFTDVARMLERVEIEVLN 267 V KG + P C PA+ ++M C + RP F + LE ++ L+ Sbjct: 396 VPRVEKGYKMDAPDGCPPAVYDVMKNCSHLDAATRPTFLQLREQLEHIKTHELH 449
>CSK_CHICK (P41239) Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase)| Length = 450 Score = 67.4 bits (163), Expect = 4e-11 Identities = 35/109 (32%), Positives = 59/109 (54%), Gaps = 3/109 (2%) Frame = -2 Query: 599 KTEGMTPETGTY--RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAA 429 K T +TG +W APE ++ + ++ K DV+SFGI+LWE+ + G +P+P + ++ Sbjct: 337 KEASSTQDTGKLPVKWTAPEALREKKFSTKSDVWSFGILLWEIYSFGRVPYPRI-PLKDV 395 Query: 428 FAVVNKGVRPAIPHDCLPALGEIMTRCWDANPDVRPPFTDVARMLERVE 282 V KG + P C + E+M +CW +P RP F + L ++ Sbjct: 396 VPRVEKGYKMDPPDGCPAIVYEVMKKCWTLDPGHRPSFHQLREQLVHIK 444
>FAK1_HUMAN (Q05397) Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK)| (Protein-tyrosine kinase 2) Length = 1052 Score = 67.4 bits (163), Expect = 4e-11 Identities = 33/94 (35%), Positives = 50/94 (53%), Gaps = 1/94 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +WMAPE I R + DV+ FG+ +WE++ G PF + + N G R +P Sbjct: 587 KWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIEN-GERLPMPP 645 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLERV 285 +C P L +MT+CW +P RP FT++ L + Sbjct: 646 NCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTI 679
>VGFR1_RAT (P53767) Vascular endothelial growth factor receptor 1 precursor (EC| 2.7.10.1) (VEGFR-1) (Tyrosine-protein kinase receptor FLT) (FLT-1) Length = 1336 Score = 67.4 bits (163), Expect = 4e-11 Identities = 31/91 (34%), Positives = 52/91 (57%), Gaps = 1/91 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +WMAPE I + Y+ K DV+S+G++LWE+ + G P+P + + + + +G+R P Sbjct: 1064 KWMAPESIFDKVYSTKSDVWSYGVLLWEIFSLGGSPYPGVQMDEDFCSRLKEGMRMRTPE 1123 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARML 294 P + +IM CW +P RP F ++ L Sbjct: 1124 YATPEIYQIMLDCWHKDPKERPRFAELVEKL 1154
>EPHB2_COTJA (Q90344) Ephrin type-B receptor 2 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor QEK5) Length = 987 Score = 67.4 bits (163), Expect = 4e-11 Identities = 34/94 (36%), Positives = 54/94 (57%), Gaps = 1/94 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 RW APE IQ+R + DV+S+GIV+WE+++ G P+ +MT Q + + R P Sbjct: 792 RWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTN-QDVINAIEQDYRLPPPM 850 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLERV 285 DC AL ++M CW + + RP F + L+++ Sbjct: 851 DCPNALHQLMLDCWQKDRNHRPKFGQIVNTLDKM 884
>EPHB2_CHICK (P28693) Ephrin type-B receptor 2 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor CEK5) Length = 1004 Score = 67.4 bits (163), Expect = 4e-11 Identities = 34/94 (36%), Positives = 54/94 (57%), Gaps = 1/94 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 RW APE IQ+R + DV+S+GIV+WE+++ G P+ +MT Q + + R P Sbjct: 809 RWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTN-QDVINAIEQDYRLPPPM 867 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLERV 285 DC AL ++M CW + + RP F + L+++ Sbjct: 868 DCPNALHQLMLDCWQKDRNHRPKFGQIVNTLDKM 901
>EPA4A_XENLA (Q91845) Ephrin type-A receptor 4-A precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor SEK-1) (xSEK-1) Length = 986 Score = 67.4 bits (163), Expect = 4e-11 Identities = 34/94 (36%), Positives = 53/94 (56%), Gaps = 1/94 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 RW APE I +R + DV+S+GIV+WE+++ G P+ +M+ Q + +G R P Sbjct: 788 RWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSN-QDVIKAIEEGYRLPPPM 846 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLERV 285 DC AL ++M CW RP F + ML+++ Sbjct: 847 DCPIALHQLMLDCWQKERSDRPKFGQIVSMLDKL 880
>VGFR1_MOUSE (P35969) Vascular endothelial growth factor receptor 1 precursor (EC| 2.7.10.1) (VEGFR-1) (Tyrosine-protein kinase receptor FLT) (FLT-1) (Embryonic receptor kinase 2) Length = 1333 Score = 67.4 bits (163), Expect = 4e-11 Identities = 31/91 (34%), Positives = 52/91 (57%), Gaps = 1/91 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +WMAPE I + Y+ K DV+S+G++LWE+ + G P+P + + + + +G+R P Sbjct: 1064 KWMAPESIFDKVYSTKSDVWSYGVLLWEIFSLGGSPYPGVQMDEDFCSRLKEGMRMRTPE 1123 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARML 294 P + +IM CW +P RP F ++ L Sbjct: 1124 YATPEIYQIMLDCWHKDPKERPRFAELVEKL 1154
>FAK1_MOUSE (P34152) Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK)| Length = 1090 Score = 67.4 bits (163), Expect = 4e-11 Identities = 33/94 (35%), Positives = 50/94 (53%), Gaps = 1/94 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +WMAPE I R + DV+ FG+ +WE++ G PF + + N G R +P Sbjct: 625 KWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIEN-GERLPMPP 683 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLERV 285 +C P L +MT+CW +P RP FT++ L + Sbjct: 684 NCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTI 717
>RON_MOUSE (Q62190) Macrophage-stimulating protein receptor precursor (EC| 2.7.10.1) (MSP receptor) (p185-Ron) (Stem cell-derived tyrosine kinase) (CDw136 antigen) [Contains: Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulating prote Length = 1378 Score = 67.4 bits (163), Expect = 4e-11 Identities = 35/101 (34%), Positives = 58/101 (57%), Gaps = 1/101 (0%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +WMA E +Q + K DV+SFG++LWEL+T G P+P++ + + +G R P Sbjct: 1229 KWMALESLQTYRFTTKSDVWSFGVLLWELLTRGAPPYPHIDPFDLSHFLA-QGRRLPQPE 1287 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLERVEIEVLNN 264 C +L +M RCW+A+P RP F + +++V +L + Sbjct: 1288 YCPDSLYHVMLRCWEADPAARPTFRALVLEVKQVVASLLGD 1328
>HCK_HUMAN (P08631) Tyrosine-protein kinase HCK (EC 2.7.10.2)| (p59-HCK/p60-HCK) (Hemopoietic cell kinase) Length = 525 Score = 67.4 bits (163), Expect = 4e-11 Identities = 35/92 (38%), Positives = 52/92 (56%), Gaps = 1/92 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +W APE I + K DV+SFGI+L E++T G +P+P M+ + A + +G R P Sbjct: 421 KWTAPEAINFGSFTIKSDVWSFGILLMEIVTYGRIPYPGMSNPEVIRA-LERGYRMPRPE 479 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLE 291 +C L IM RCW P+ RP F + +L+ Sbjct: 480 NCPEELYNIMMRCWKNRPEERPTFEYIQSVLD 511
>FAK1_RAT (O35346) Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK)| Length = 1055 Score = 67.4 bits (163), Expect = 4e-11 Identities = 33/94 (35%), Positives = 50/94 (53%), Gaps = 1/94 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +WMAPE I R + DV+ FG+ +WE++ G PF + + N G R +P Sbjct: 587 KWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIEN-GERLPMPP 645 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLERV 285 +C P L +MT+CW +P RP FT++ L + Sbjct: 646 NCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTI 679
>EPHA3_RAT (O08680) Ephrin type-A receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor REK4) (TYRO-4) Length = 984 Score = 67.4 bits (163), Expect = 4e-11 Identities = 33/94 (35%), Positives = 55/94 (58%), Gaps = 1/94 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 RW +PE +R + DV+S+GIVLWE+++ G P+ M+ Q V++G R +P Sbjct: 790 RWTSPEATAYRKFTSASDVWSYGIVLWEVMSYGERPYWEMSN-QDVIKAVDEGYRLPLPM 848 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLERV 285 DC AL ++M CW + + RP F + +L+++ Sbjct: 849 DCPAALYQLMLDCWQKDRNNRPKFEQIVSILDKL 882
>ROS_AVISU (P00529) Tyrosine-protein kinase transforming protein ros (EC| 2.7.10.1) Length = 402 Score = 67.4 bits (163), Expect = 4e-11 Identities = 34/104 (32%), Positives = 57/104 (54%), Gaps = 1/104 (0%) Frame = -2 Query: 593 EGMTPETGTYRWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVV 417 EG+ P RWMAPE + + DV++FG+++WE +T G P+P ++ ++ V Sbjct: 274 EGLLP----VRWMAPESLIDGVFTNHSDVWAFGVLVWETLTLGQQPYPGLSNIEVLHH-V 328 Query: 416 NKGVRPAIPHDCLPALGEIMTRCWDANPDVRPPFTDVARMLERV 285 G R P++C + ++MTRCW +P RP F + L+ + Sbjct: 329 RSGGRLESPNNCPDDIRDLMTRCWAQDPHNRPTFFYIQHKLQEI 372
>EPHA3_HUMAN (P29320) Ephrin type-A receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ETK1) (HEK) (HEK4) Length = 983 Score = 67.4 bits (163), Expect = 4e-11 Identities = 34/94 (36%), Positives = 55/94 (58%), Gaps = 1/94 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 RW +PE I +R + DV+S+GIVLWE+++ G P+ M+ Q V++G R P Sbjct: 789 RWTSPEAIAYRKFTSASDVWSYGIVLWEVMSYGERPYWEMSN-QDVIKAVDEGYRLPPPM 847 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLERV 285 DC AL ++M CW + + RP F + +L+++ Sbjct: 848 DCPAALYQLMLDCWQKDRNNRPKFEQIVSILDKL 881
>UFO_MOUSE (Q00993) Tyrosine-protein kinase receptor UFO precursor (EC| 2.7.10.1) (Adhesion-related kinase) Length = 888 Score = 67.4 bits (163), Expect = 4e-11 Identities = 34/92 (36%), Positives = 52/92 (56%), Gaps = 1/92 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +W+A E + R Y K DV+SFG+ +WE+ T G P+P + + + + +G R P Sbjct: 708 KWIAIESLADRVYTSKSDVWSFGVTMWEIATRGQTPYPGVENSE-IYDYLRQGNRLKQPV 766 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLE 291 D L L +M+RCW+ NP RP F ++ LE Sbjct: 767 DFLDGLYSLMSRCWELNPRDRPSFAELREDLE 798
>EPHA8_HUMAN (P29322) Ephrin type-A receptor 8 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EEK) (EPH- and ELK-related kinase) (HEK3) Length = 1005 Score = 67.4 bits (163), Expect = 4e-11 Identities = 40/117 (34%), Positives = 60/117 (51%), Gaps = 1/117 (0%) Frame = -2 Query: 638 SRLLTSEVARIEVKTEGMTPETGTYRWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTL 462 SR+L + T G P RW APE I R ++ DV+SFG+V+WE++ G Sbjct: 782 SRVLEDDPDAAYTTTGGKIP----IRWTAPEAIAFRTFSSASDVWSFGVVMWEVLAYGER 837 Query: 461 PFPNMTAVQAAFAVVNKGVRPAIPHDCLPALGEIMTRCWDANPDVRPPFTDVARMLE 291 P+ NMT + + V +G R P C AL ++M CW + RP F+ + +L+ Sbjct: 838 PYWNMTN-RDVISSVEEGYRLPAPMGCPHALHQLMLDCWHKDRAQRPRFSQIVSVLD 893
>ABL_MLVAB (P00521) Tyrosine-protein kinase transforming protein Abl (EC| 2.7.10.2) (V-abl) Length = 746 Score = 67.4 bits (163), Expect = 4e-11 Identities = 34/106 (32%), Positives = 57/106 (53%), Gaps = 3/106 (2%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +W APE + + ++ K DV++FG++LWE+ T G P+P + Q + ++ K R P Sbjct: 290 KWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQ-VYELLEKDYRMERPE 348 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLERV--EIEVLNNVRK 255 C + E+M CW NP RP F ++ + E + E + + V K Sbjct: 349 GCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQESSISDEVEK 394
>YRK_CHICK (Q02977) Proto-oncogene tyrosine-protein kinase Yrk (EC 2.7.10.2)| (p60-Yrk) (Yes-related kinase) Length = 535 Score = 67.4 bits (163), Expect = 4e-11 Identities = 35/92 (38%), Positives = 50/92 (54%), Gaps = 1/92 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +W APE + K DV+SFGI+L EL+T G +P+P M + V +G R P Sbjct: 429 KWTAPEAALFGKFTIKSDVWSFGILLTELVTKGRVPYPGMNN-REVLEQVERGYRMQCPG 487 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLE 291 C P+L ++M +CW P+ RP F + LE Sbjct: 488 GCPPSLHDVMVQCWKREPEERPTFEYLQSFLE 519
>ABL1_MOUSE (P00520) Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2)| (p150) (c-ABL) (Abelson murine leukemia viral oncogene homolog 1) Length = 1123 Score = 67.4 bits (163), Expect = 4e-11 Identities = 34/106 (32%), Positives = 57/106 (53%), Gaps = 3/106 (2%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +W APE + + ++ K DV++FG++LWE+ T G P+P + Q + ++ K R P Sbjct: 404 KWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQ-VYELLEKDYRMERPE 462 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLERV--EIEVLNNVRK 255 C + E+M CW NP RP F ++ + E + E + + V K Sbjct: 463 GCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQESSISDEVEK 508
>LIMK1_RAT (P53669) LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1)| Length = 647 Score = 67.4 bits (163), Expect = 4e-11 Identities = 38/105 (36%), Positives = 57/105 (54%), Gaps = 1/105 (0%) Frame = -2 Query: 572 GTYRWMAPEMIQHRPYNQKVDVYSFGIVLWELITGTLPFPNMTAVQAAFAVVNKG-VRPA 396 G WMAPEMI R Y++KVDV+SFGIVL E+I P+ F + +G + Sbjct: 511 GNPYWMAPEMINGRSYDEKVDVFSFGIVLCEIIGRVNADPDYLPRTMDFGLNVRGFLDRY 570 Query: 395 IPHDCLPALGEIMTRCWDANPDVRPPFTDVARMLERVEIEVLNNV 261 P +C P+ I RC D +P+ RP F + + LE + + + ++ Sbjct: 571 CPPNCPPSFFPITVRCCDLDPEKRPSFVKLEQWLETLRMHLAGHL 615
>EPHA8_MOUSE (O09127) Ephrin type-A receptor 8 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EEK) (EPH- and ELK-related kinase) Length = 1004 Score = 67.0 bits (162), Expect = 5e-11 Identities = 36/92 (39%), Positives = 51/92 (55%), Gaps = 1/92 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 RW APE I R ++ DV+SFG+V+WE++ G P+ NMT Q + V +G R P Sbjct: 802 RWTAPEAIAFRTFSSASDVWSFGVVMWEVLAYGERPYWNMTN-QDVISSVEEGYRLPAPM 860 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLE 291 C AL ++M CW + RP F V +L+ Sbjct: 861 GCPRALHQLMLDCWHKDRAQRPRFAHVVSVLD 892
>INSR_AEDAE (Q93105) Insulin-like receptor precursor (EC 2.7.10.1) (MIR)| [Contains: Insulin-like receptor alpha chain; Insulin-like receptor beta chain] Length = 1390 Score = 67.0 bits (162), Expect = 5e-11 Identities = 35/98 (35%), Positives = 53/98 (54%), Gaps = 1/98 (1%) Frame = -2 Query: 596 TEGMTPETGTYRWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAV 420 T+G P RWMAPE ++ ++ DV+S+G+VLWE+ T + P+ +T Q V Sbjct: 1197 TKGFLP----VRWMAPESLKDGIFSSSSDVFSYGVVLWEMATLASQPYQGLTNDQVLRYV 1252 Query: 419 VNKGVRPAIPHDCLPALGEIMTRCWDANPDVRPPFTDV 306 ++ GV P +C L +M RCW P RP F ++ Sbjct: 1253 IDGGVMER-PENCPDNLYNLMRRCWQHRPTARPTFMEI 1289
>LIMK1_MOUSE (P53668) LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1) (KIZ-1)| Length = 647 Score = 67.0 bits (162), Expect = 5e-11 Identities = 38/101 (37%), Positives = 55/101 (54%), Gaps = 1/101 (0%) Frame = -2 Query: 572 GTYRWMAPEMIQHRPYNQKVDVYSFGIVLWELITGTLPFPNMTAVQAAFAVVNKG-VRPA 396 G WMAPEMI R Y++KVDV+SFGIVL E+I P+ F + +G + Sbjct: 511 GNPYWMAPEMINGRSYDEKVDVFSFGIVLCEIIGRVNADPDYLPRTMDFGLNVRGFLDRY 570 Query: 395 IPHDCLPALGEIMTRCWDANPDVRPPFTDVARMLERVEIEV 273 P +C P+ I RC D +P+ RP F + + LE + + + Sbjct: 571 CPPNCPPSFFPITVRCCDLDPEKRPSFVKLEQWLETLRMHL 611
>LIMK1_HUMAN (P53667) LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1)| Length = 647 Score = 67.0 bits (162), Expect = 5e-11 Identities = 38/105 (36%), Positives = 56/105 (53%), Gaps = 1/105 (0%) Frame = -2 Query: 572 GTYRWMAPEMIQHRPYNQKVDVYSFGIVLWELITGTLPFPNMTAVQAAFAVVNKG-VRPA 396 G WMAPEMI R Y++KVDV+SFGIVL E+I P+ F + +G + Sbjct: 511 GNPYWMAPEMINGRSYDEKVDVFSFGIVLCEIIGRVNADPDYLPRTMDFGLNVRGFLDRY 570 Query: 395 IPHDCLPALGEIMTRCWDANPDVRPPFTDVARMLERVEIEVLNNV 261 P +C P+ I RC D +P+ RP F + LE + + + ++ Sbjct: 571 CPPNCPPSFFPITVRCCDLDPEKRPSFVKLEHWLETLRMHLAGHL 615
>FAK2_RAT (P70600) Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal| adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) Length = 1009 Score = 66.6 bits (161), Expect = 6e-11 Identities = 39/112 (34%), Positives = 60/112 (53%), Gaps = 5/112 (4%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +WM+PE I R + DV+ F + +WE+++ G PF + + V+ KG R P Sbjct: 590 KWMSPESINFRRFTTASDVWMFAVCMWEILSFGKQPFFWLEN-KDVIGVLEKGDRLPKPE 648 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLERV-EIE---VLNNVRKARFR 243 C P L +MTRCWD +P RP FT++ L + ++E + R AR+R Sbjct: 649 LCPPVLYTLMTRCWDYDPSDRPRFTELVCSLSDIYQMERDIAIEQERNARYR 700
>FAK2_MOUSE (Q9QVP9) Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal| adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) (Related adhesion focal tyrosine kinas Length = 1009 Score = 66.6 bits (161), Expect = 6e-11 Identities = 39/110 (35%), Positives = 57/110 (51%), Gaps = 8/110 (7%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +WM+PE I R + DV+ F + +WE+++ G PF + + V+ KG R P Sbjct: 590 KWMSPESINFRRFTTASDVWMFAVCMWEILSFGKQPFFWLEN-KDVIGVLEKGDRLPKPE 648 Query: 386 DCLPALGEIMTRCWDANPDVRPPFT-------DVARMLERVEIEVLNNVR 258 C P L +MTRCWD +P RP FT D+ +M + + IE N R Sbjct: 649 LCPPVLYTLMTRCWDYDPSDRPRFTELVCSLSDIYQMEKDIAIEQERNAR 698
>FAK2_HUMAN (Q14289) Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal| adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) (Related adhesion focal tyrosine kinas Length = 1009 Score = 66.6 bits (161), Expect = 6e-11 Identities = 40/112 (35%), Positives = 60/112 (53%), Gaps = 5/112 (4%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +WM+PE I R + DV+ F + +WE+++ G PF + + V+ KG R P Sbjct: 590 KWMSPESINFRRFTTASDVWMFAVCMWEILSFGKQPFFWLEN-KDVIGVLEKGDRLPKPD 648 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLERV-EIE---VLNNVRKARFR 243 C P L +MTRCWD +P RP FT++ L V ++E + R AR+R Sbjct: 649 LCPPVLYTLMTRCWDYDPSDRPRFTELVCSLSDVYQMEKDIAMEQERNARYR 700
>LCK_SAISC (Q95KR7) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) Length = 508 Score = 66.6 bits (161), Expect = 6e-11 Identities = 34/92 (36%), Positives = 53/92 (57%), Gaps = 1/92 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +W APE I + + K DV+SFGI++ E++T G +P+P MT + + +G R P Sbjct: 404 KWTAPEAINYGTFTIKSDVWSFGILMTEIVTHGRIPYPGMTNPE-VIQNLERGYRMPRPD 462 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLE 291 +C L ++M +CW PD RP F + +LE Sbjct: 463 NCPEELYKLMMQCWRERPDDRPTFDYLRSVLE 494
>VGFR1_HUMAN (P17948) Vascular endothelial growth factor receptor 1 precursor (EC| 2.7.10.1) (VEGFR-1) (Vascular permeability factor receptor) (Tyrosine-protein kinase receptor FLT) (Flt-1) (Tyrosine-protein kinase FRT) (Fms-like tyrosine kinase 1) Length = 1338 Score = 66.6 bits (161), Expect = 6e-11 Identities = 31/91 (34%), Positives = 52/91 (57%), Gaps = 1/91 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +WMAPE I + Y+ K DV+S+G++LWE+ + G P+P + + + + +G+R P Sbjct: 1064 KWMAPESIFDKIYSTKSDVWSYGVLLWEIFSLGGSPYPGVQMDEDFCSRLREGMRMRAPE 1123 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARML 294 P + +IM CW +P RP F ++ L Sbjct: 1124 YSTPEIYQIMLDCWHRDPKERPRFAELVEKL 1154
>TXK_MOUSE (P42682) Tyrosine-protein kinase TXK (EC 2.7.10.2) (PTK-RL-18)| (Resting lymphocyte kinase) Length = 527 Score = 66.6 bits (161), Expect = 6e-11 Identities = 31/94 (32%), Positives = 53/94 (56%), Gaps = 1/94 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +W PE+ Y+ K DV+SFG+++WE+ T G +PF N + +Q A +++G R PH Sbjct: 431 KWCPPEVFHFNKYSSKSDVWSFGVLMWEVFTEGKMPFENKSNLQVVEA-ISQGFRLYRPH 489 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLERV 285 + +M CW +P RP F ++ ++L + Sbjct: 490 LAPMTIYRVMYSCWHESPKGRPTFAELLQVLTEI 523
>MET_HUMAN (P08581) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1390 Score = 66.6 bits (161), Expect = 6e-11 Identities = 32/94 (34%), Positives = 54/94 (57%), Gaps = 1/94 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +WMA E +Q + + K DV+SFG+VLWEL+T G P+P++ ++ +G R P Sbjct: 1248 KWMALESLQTQKFTTKSDVWSFGVVLWELMTRGAPPYPDVNTFDITVYLL-QGRRLLQPE 1306 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLERV 285 C L E+M +CW ++RP F+++ + + Sbjct: 1307 YCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAI 1340
>EPHB3_CHICK (Q07498) Ephrin type-B receptor 3 (EC 2.7.10.1) (Tyrosine-protein| kinase receptor CEK10) (Fragment) Length = 988 Score = 66.6 bits (161), Expect = 6e-11 Identities = 37/115 (32%), Positives = 62/115 (53%), Gaps = 1/115 (0%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 RW APE I +R + DV+S+GIV+WE+++ G P+ +M+ Q V + R P Sbjct: 793 RWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSN-QDVINAVEQDYRLPPPM 851 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLERVEIEVLNNVRKARFRCCISQPM 222 DC AL ++M CW + ++RP F + L+++ + A + +SQP+ Sbjct: 852 DCPTALHQLMLDCWVRDRNLRPKFAQIVNTLDKLIRNAASLKVIASVQSGVSQPL 906
>KSYK_MOUSE (P48025) Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine| kinase) Length = 629 Score = 66.2 bits (160), Expect = 8e-11 Identities = 38/125 (30%), Positives = 63/125 (50%), Gaps = 1/125 (0%) Frame = -2 Query: 638 SRLLTSEVARIEVKTEGMTPETGTYRWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTL 462 S+ L ++ + +T G P +W APE I + ++ K DV+SFG+++WE + G Sbjct: 510 SKALRADENYYKAQTHGKWP----VKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQK 565 Query: 461 PFPNMTAVQAAFAVVNKGVRPAIPHDCLPALGEIMTRCWDANPDVRPPFTDVARMLERVE 282 P+ M + A++ KG R P C + ++M CW + + RP FT V L Sbjct: 566 PYRGMKGSEVT-AMLEKGERMGCPAGCPREMYDLMNLCWTYDVENRPGFTAVELRLRNYY 624 Query: 281 IEVLN 267 +V+N Sbjct: 625 YDVVN 629
>TEC_HUMAN (P42680) Tyrosine-protein kinase Tec (EC 2.7.10.2)| Length = 631 Score = 66.2 bits (160), Expect = 8e-11 Identities = 43/132 (32%), Positives = 65/132 (49%), Gaps = 14/132 (10%) Frame = -2 Query: 629 LTSEVARIEVKTEGM---------TPETGT---YRWMAPEMIQHRPYNQKVDVYSFGIVL 486 L SE ++V GM T +G +W PE+ + ++ K DV+SFG+++ Sbjct: 496 LVSEAGVVKVSDFGMARYFLDDQYTSSSGAKFPVKWCPPEVFNYSRFSSKSDVWSFGVLM 555 Query: 485 WELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPHDCLPALGEIMTRCWDANPDVRPPFTD 309 WE+ T G +PF T + +V +G R P + E+M RCW P+ RP F D Sbjct: 556 WEVFTEGRMPFEKYTNYEVV-TMVTRGHRLYQPKLASNYVYEVMLRCWQEKPEGRPSFED 614 Query: 308 VARML-ERVEIE 276 + R + E VE E Sbjct: 615 LLRTIDELVECE 626
>ABL_FSVHY (P10447) Tyrosine-protein kinase transforming protein Abl (EC| 2.7.10.2) (V-abl) Length = 439 Score = 66.2 bits (160), Expect = 8e-11 Identities = 37/115 (32%), Positives = 58/115 (50%), Gaps = 4/115 (3%) Frame = -2 Query: 638 SRLLTSEVARIEVKTEGMTPETGT---YRWMAPEMIQHRPYNQKVDVYSFGIVLWELIT- 471 SRL+T + T GT +W APE + + ++ K DV++FG++LWE+ T Sbjct: 334 SRLMTGDT---------YTAHAGTKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATY 384 Query: 470 GTLPFPNMTAVQAAFAVVNKGVRPAIPHDCLPALGEIMTRCWDANPDVRPPFTDV 306 G P+P + Q + ++ K R P C + E+M CW NP RP F ++ Sbjct: 385 GMSPYPGIDLSQ-VYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPAFAEI 438
>ALK_HUMAN (Q9UM73) ALK tyrosine kinase receptor precursor (EC 2.7.10.1)| (Anaplastic lymphoma kinase) (CD246 antigen) Length = 1620 Score = 66.2 bits (160), Expect = 8e-11 Identities = 35/95 (36%), Positives = 52/95 (54%), Gaps = 1/95 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +WM PE + K D +SFG++LWE+ + G +P+P+ + Q V G R P Sbjct: 1294 KWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPSKSN-QEVLEFVTSGGRMDPPK 1352 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLERVE 282 +C + IMT+CW P+ RP F A +LER+E Sbjct: 1353 NCPGPVYRIMTQCWQHQPEDRPNF---AIILERIE 1384
>MERTK_RAT (P57097) Proto-oncogene tyrosine-protein kinase MER precursor (EC| 2.7.10.1) (C-mer) (Receptor tyrosine kinase MerTK) Length = 994 Score = 66.2 bits (160), Expect = 8e-11 Identities = 35/94 (37%), Positives = 53/94 (56%), Gaps = 1/94 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +W+A E + R Y K DV++FG+ +WE+ T G P+P + + + + G R P Sbjct: 760 KWIAIESLADRVYTSKSDVWAFGVTMWEIATRGMTPYPGVQNHEM-YDYLLHGHRLKQPE 818 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLERV 285 DCL L EIM CW A+P RP F+ + LE++ Sbjct: 819 DCLDDLYEIMYSCWSADPLDRPTFSVLRLQLEKL 852
>ROS_CHICK (P08941) Proto-oncogene tyrosine-protein kinase ROS precursor (EC| 2.7.10.1) (c-ros-1) Length = 2311 Score = 66.2 bits (160), Expect = 8e-11 Identities = 31/94 (32%), Positives = 53/94 (56%), Gaps = 1/94 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 RWMAPE + + DV++FG+++WE +T G P+P ++ ++ V G R P+ Sbjct: 2143 RWMAPESLIDGVFTNHSDVWAFGVLVWETLTLGQQPYPGLSNIEVLHH-VRSGGRLESPN 2201 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLERV 285 +C + ++MTRCW +P RP F + L+ + Sbjct: 2202 NCPDDIRDLMTRCWAQDPHNRPTFFYIQHKLQEI 2235
>EPHA3_CHICK (P29318) Ephrin type-A receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ETK1) (CEK4) Length = 983 Score = 66.2 bits (160), Expect = 8e-11 Identities = 33/94 (35%), Positives = 54/94 (57%), Gaps = 1/94 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 RW +PE I +R + D +S+GIVLWE+++ G P+ M + Q V++G R P Sbjct: 789 RWTSPEAIAYRKFTSASDAWSYGIVLWEVMSYGERPYWEM-SFQDVIKAVDEGYRLPPPM 847 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLERV 285 DC AL ++M CW + + RP F + +L+++ Sbjct: 848 DCPAALYQLMLDCWQKDRNNRPKFEQIVSILDKL 881
>ALK_MOUSE (P97793) ALK tyrosine kinase receptor precursor (EC 2.7.10.1)| (Anaplastic lymphoma kinase) (CD246 antigen) Length = 1621 Score = 66.2 bits (160), Expect = 8e-11 Identities = 35/95 (36%), Positives = 52/95 (54%), Gaps = 1/95 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +WM PE + K D +SFG++LWE+ + G +P+P+ + Q V G R P Sbjct: 1298 KWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPSKSN-QEVLEFVTSGGRMDPPK 1356 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLERVE 282 +C + IMT+CW P+ RP F A +LER+E Sbjct: 1357 NCPGPVYRIMTQCWQHQPEDRPNF---AIILERIE 1388
>YES_HUMAN (P07947) Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2)| (p61-Yes) (c-Yes) Length = 542 Score = 65.9 bits (159), Expect = 1e-10 Identities = 35/92 (38%), Positives = 49/92 (53%), Gaps = 1/92 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +W APE + + K DV+SFGI+ EL+T G +P+P M + V +G R P Sbjct: 436 KWTAPEAALYGRFTIKSDVWSFGILQTELVTKGRVPYPGMVN-REVLEQVERGYRMPCPQ 494 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLE 291 C +L E+M CW +PD RP F + LE Sbjct: 495 GCPESLHELMNLCWKKDPDERPTFEYIQSFLE 526
>EPHB3_MOUSE (P54754) Ephrin type-B receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor MDK-5) (Developmental kinase 5) (SEK-4) Length = 993 Score = 65.9 bits (159), Expect = 1e-10 Identities = 33/94 (35%), Positives = 55/94 (58%), Gaps = 1/94 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 RW APE I +R + DV+S+GIV+WE+++ G P+ +M+ Q V + R P Sbjct: 798 RWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSN-QDVINAVEQDYRLPPPM 856 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLERV 285 DC AL ++M CW + ++RP F+ + L+++ Sbjct: 857 DCPTALHQLMLDCWVRDRNLRPKFSQIVNTLDKL 890
>YES_MOUSE (Q04736) Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2)| (p61-Yes) (c-Yes) Length = 540 Score = 65.9 bits (159), Expect = 1e-10 Identities = 35/92 (38%), Positives = 49/92 (53%), Gaps = 1/92 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +W APE + + K DV+SFGI+ EL+T G +P+P M + V +G R P Sbjct: 434 KWTAPEAALYGRFTIKSDVWSFGILQTELVTKGRVPYPGMVN-REVLEQVERGYRMPCPQ 492 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLE 291 C +L E+M CW +PD RP F + LE Sbjct: 493 GCPESLHELMNLCWKKDPDERPTFEYIQSFLE 524
>HCK_RAT (P50545) Tyrosine-protein kinase HCK (EC 2.7.10.2) (p56-HCK)| (Hemopoietic cell kinase) Length = 502 Score = 65.9 bits (159), Expect = 1e-10 Identities = 35/92 (38%), Positives = 51/92 (55%), Gaps = 1/92 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +W APE I + K DV+SFGI+L E++T G +P+P M+ + A + G R P Sbjct: 398 KWTAPEAINFGSFTIKSDVWSFGILLMEIVTYGRIPYPGMSNPEVIRA-LEHGYRMPRPD 456 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLE 291 +C L IM RCW P+ RP F + +L+ Sbjct: 457 NCPEELYSIMIRCWKNRPEERPTFEYIQSVLD 488
>HCK_MOUSE (P08103) Tyrosine-protein kinase HCK (EC 2.7.10.2)| (p56-HCK/p59-HCK) (Hemopoietic cell kinase) (B-cell/myeloid kinase) (BMK) Length = 523 Score = 65.9 bits (159), Expect = 1e-10 Identities = 35/92 (38%), Positives = 51/92 (55%), Gaps = 1/92 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +W APE I + K DV+SFGI+L E++T G +P+P M+ + A + G R P Sbjct: 419 KWTAPEAINFGSFTIKSDVWSFGILLMEIVTYGRIPYPGMSNPEVIRA-LEHGYRMPRPD 477 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLE 291 +C L IM RCW P+ RP F + +L+ Sbjct: 478 NCPEELYNIMIRCWKNRPEERPTFEYIQSVLD 509
>VGFR2_COTJA (P52583) Vascular endothelial growth factor receptor 2 precursor (EC| 2.7.10.1) (VEGFR-2) (Endothelial kinase receptor EK1) (Quek 1) (Quek1) Length = 1348 Score = 65.9 bits (159), Expect = 1e-10 Identities = 35/108 (32%), Positives = 56/108 (51%), Gaps = 1/108 (0%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +WMAPE I R Y + DV+SFG++LWE+ + G P+P + + + +G R P Sbjct: 1063 KWMAPETIFDRVYTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAPD 1122 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLERVEIEVLNNVRKARFR 243 P + + M CW +P RP F+++ +E L N+ +A R Sbjct: 1123 YTTPEMYQTMLDCWHGDPKQRPTFSEL--------VEHLGNLLQANVR 1162
>ILK_CAVPO (P57044) Integrin-linked protein kinase (EC 2.7.11.1)| (Beta-integrin-linked kinase) Length = 451 Score = 65.9 bits (159), Expect = 1e-10 Identities = 35/120 (29%), Positives = 67/120 (55%), Gaps = 4/120 (3%) Frame = -2 Query: 629 LTSEVARIEVKTEGMTP-ETGTYRWMAPEMIQHRPYN---QKVDVYSFGIVLWELITGTL 462 +T+ ++ +VK P W+APE +Q +P + + D++SF ++LWEL+T + Sbjct: 331 MTARISMADVKFSFQCPGRMYAPAWVAPEALQKKPEDTNRRSADMWSFAVLLWELVTREV 390 Query: 461 PFPNMTAVQAAFAVVNKGVRPAIPHDCLPALGEIMTRCWDANPDVRPPFTDVARMLERVE 282 PF +++ ++ V +G RP IP P + ++M C + +P RP F + +LE+++ Sbjct: 391 PFADLSNMEIGMKVALEG-RPTIPPGISPHVCKLMKICMNEDPAKRPKFDMIVPILEKMQ 449
>LCK_HUMAN (P06239) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK) (T cell-specific protein-tyrosine kinase) Length = 508 Score = 65.9 bits (159), Expect = 1e-10 Identities = 34/92 (36%), Positives = 52/92 (56%), Gaps = 1/92 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +W APE I + + K DV+SFGI+L E++T G +P+P MT + + +G R P Sbjct: 404 KWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPE-VIQNLERGYRMVRPD 462 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLE 291 +C L ++M CW P+ RP F + +LE Sbjct: 463 NCPEELYQLMRLCWKERPEDRPTFDYLRSVLE 494
>EPHB3_HUMAN (P54753) Ephrin type-B receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor HEK-2) Length = 998 Score = 65.9 bits (159), Expect = 1e-10 Identities = 33/94 (35%), Positives = 55/94 (58%), Gaps = 1/94 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 RW APE I +R + DV+S+GIV+WE+++ G P+ +M+ Q V + R P Sbjct: 803 RWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSN-QDVINAVEQDYRLPPPM 861 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLERV 285 DC AL ++M CW + ++RP F+ + L+++ Sbjct: 862 DCPTALHQLMLDCWVRDRNLRPKFSQIVNTLDKL 895
>TEC_MOUSE (P24604) Tyrosine-protein kinase Tec (EC 2.7.10.2)| Length = 630 Score = 65.5 bits (158), Expect = 1e-10 Identities = 35/98 (35%), Positives = 53/98 (54%), Gaps = 2/98 (2%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +W PE+ + ++ K DV+SFG+++WE+ T G +PF T + +V +G R P Sbjct: 529 KWCPPEVFNYSRFSSKSDVWSFGVLMWEIFTEGRMPFEKNTNYEVV-TMVTRGHRLHRPK 587 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARML-ERVEIE 276 L E+M RCW P+ RP D+ R + E VE E Sbjct: 588 LATKYLYEVMLRCWQERPEGRPSLEDLLRTIDELVECE 625
>MET_OTOGA (Q2QLH6) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1382 Score = 65.5 bits (158), Expect = 1e-10 Identities = 31/94 (32%), Positives = 54/94 (57%), Gaps = 1/94 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +WMA E +Q + + K DV+SFG++LWEL+T G P+P++ ++ +G R P Sbjct: 1249 KWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLL-QGRRLLQPE 1307 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLERV 285 C L E+M +CW ++RP F+++ + + Sbjct: 1308 YCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAI 1341
>MET_MICMU (Q2QL89) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1382 Score = 65.5 bits (158), Expect = 1e-10 Identities = 31/94 (32%), Positives = 54/94 (57%), Gaps = 1/94 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +WMA E +Q + + K DV+SFG++LWEL+T G P+P++ ++ +G R P Sbjct: 1249 KWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLL-QGRRLLQPE 1307 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLERV 285 C L E+M +CW ++RP F+++ + + Sbjct: 1308 YCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAI 1341
>MET_CANFA (Q75ZY9) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1382 Score = 65.5 bits (158), Expect = 1e-10 Identities = 31/94 (32%), Positives = 54/94 (57%), Gaps = 1/94 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +WMA E +Q + + K DV+SFG++LWEL+T G P+P++ ++ +G R P Sbjct: 1249 KWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLL-QGRRLLQPE 1307 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLERV 285 C L E+M +CW ++RP F+++ + + Sbjct: 1308 YCPDPLYEVMLKCWHPRAELRPSFSELVSRISAI 1341
>FRK_HUMAN (P42685) Tyrosine-protein kinase FRK (EC 2.7.10.2) (Nuclear| tyrosine protein kinase RAK) Length = 505 Score = 65.5 bits (158), Expect = 1e-10 Identities = 35/92 (38%), Positives = 51/92 (55%), Gaps = 1/92 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +W APE I+ ++ K DV+SFGI+L+E+IT G +P+ MT Q ++ + R P Sbjct: 398 KWTAPEAIRSNKFSIKSDVWSFGILLYEIITYGKMPYSGMTGAQ-VIQMLAQNYRLPQPS 456 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLE 291 +C IM CW+A P RP F + LE Sbjct: 457 NCPQQFYNIMLECWNAEPKERPTFETLRWKLE 488
>MERTK_HUMAN (Q12866) Proto-oncogene tyrosine-protein kinase MER precursor (EC| 2.7.10.1) (C-mer) (Receptor tyrosine kinase MerTK) Length = 999 Score = 65.5 bits (158), Expect = 1e-10 Identities = 38/103 (36%), Positives = 58/103 (56%), Gaps = 1/103 (0%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +W+A E + R Y K DV++FG+ +WE+ T G P+P + + + + G R P Sbjct: 765 KWIAIESLADRVYTSKSDVWAFGVTMWEIRTRGMTPYPGVQNHEM-YDYLLHGHRLKQPE 823 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLERVEIEVLNNVR 258 DCL L EIM CW +P RP F+ + LE++ +E L +VR Sbjct: 824 DCLDELYEIMYSCWRTDPLDRPTFSVLRLQLEKL-LESLPDVR 865
>HCK_MACFA (Q95M30) Tyrosine-protein kinase HCK (EC 2.7.10.2) (p56-HCK)| (Hemopoietic cell kinase) Length = 503 Score = 65.5 bits (158), Expect = 1e-10 Identities = 35/92 (38%), Positives = 51/92 (55%), Gaps = 1/92 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +W APE I K DV+SFGI+L E++T G +P+P M+ + A+ +G R P Sbjct: 399 KWTAPEAINFGSSTIKSDVWSFGILLMEIVTYGRIPYPGMSNPEVIRAL-ERGYRMPRPE 457 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLE 291 +C L IM RCW P+ RP F + +L+ Sbjct: 458 NCPEELYNIMMRCWKNRPEERPTFEYIQSVLD 489
>YES_XENLA (P10936) Tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes)| Length = 536 Score = 65.5 bits (158), Expect = 1e-10 Identities = 35/92 (38%), Positives = 49/92 (53%), Gaps = 1/92 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +W APE + + K DV+SFGI+L EL+ G +P+P M + V +G R P Sbjct: 430 KWTAPEAALYGRFTIKSDVWSFGILLTELVAKGRVPYPGMVN-REVLEQVERGYRMPCPQ 488 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLE 291 C +L E+M CW +PD RP F + LE Sbjct: 489 RCPESLHELMKLCWKKDPDERPTFEYIQSFLE 520
>EPB1B_XENLA (Q91736) Ephrin type-B receptor 1-B (EC 2.7.10.1) (Tyrosine-protein| kinase receptor XELK) (Fragment) Length = 902 Score = 65.5 bits (158), Expect = 1e-10 Identities = 32/94 (34%), Positives = 55/94 (58%), Gaps = 1/94 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 RW APE I++R + DV+S+GIV+WE+++ G P+ +M+ Q + + R P Sbjct: 707 RWTAPEAIRYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSN-QDVINAIEQDYRLPPPM 765 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLERV 285 DC AL ++M CW + + RP F ++ L+++ Sbjct: 766 DCPAALHQLMLDCWQKDRNSRPRFGEIVNTLDKM 799
>MERTK_MOUSE (Q60805) Proto-oncogene tyrosine-protein kinase MER precursor (EC| 2.7.10.1) (C-mer) (Receptor tyrosine kinase MerTK) Length = 994 Score = 65.5 bits (158), Expect = 1e-10 Identities = 34/94 (36%), Positives = 53/94 (56%), Gaps = 1/94 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +W+A E + R Y K DV++FG+ +WE+ T G P+P + + + + G R P Sbjct: 760 KWIAIESLADRVYTSKSDVWAFGVTMWEITTRGMTPYPGVQNHEM-YDYLLHGHRLKQPE 818 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLERV 285 DCL L +IM CW A+P RP F+ + LE++ Sbjct: 819 DCLDELYDIMYSCWSADPLDRPTFSVLRLQLEKL 852
>HTK7_HYDAT (Q25197) Putative insulin-like peptide receptor precursor (EC| 2.7.10.1) Length = 1477 Score = 65.5 bits (158), Expect = 1e-10 Identities = 34/92 (36%), Positives = 51/92 (55%), Gaps = 1/92 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 RWMAPE ++ ++ DV+SFG+VLWE+ T + P+ T Q V++ G P Sbjct: 1217 RWMAPESLKDGIFSTASDVWSFGVVLWEICTLASQPYQGKTNEQVLNFVLSNG-HLDYPE 1275 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLE 291 C L E M+ CW +P +RP F ++ +LE Sbjct: 1276 GCDYQLREFMSLCWHRDPKMRPSFLEIVHVLE 1307
>EPHB1_RAT (P09759) Ephrin type-B receptor 1 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EPH-2) (ELK) Length = 984 Score = 65.5 bits (158), Expect = 1e-10 Identities = 32/94 (34%), Positives = 54/94 (57%), Gaps = 1/94 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 RW APE I +R + DV+S+GIV+WE+++ G P+ +M+ Q + + R P Sbjct: 789 RWTAPEAIAYRKFTSASDVWSYGIVMWEVMSFGERPYWDMSN-QDVINAIEQDYRLPPPM 847 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLERV 285 DC AL ++M CW + + RP F ++ L+++ Sbjct: 848 DCPAALHQLMLDCWQKDRNSRPRFAEIVNTLDKM 881
>EPHB1_HUMAN (P54762) Ephrin type-B receptor 1 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EPH-2) (NET) (HEK6) (ELK) Length = 984 Score = 65.5 bits (158), Expect = 1e-10 Identities = 32/94 (34%), Positives = 54/94 (57%), Gaps = 1/94 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 RW APE I +R + DV+S+GIV+WE+++ G P+ +M+ Q + + R P Sbjct: 789 RWTAPEAIAYRKFTSASDVWSYGIVMWEVMSFGERPYWDMSN-QDVINAIEQDYRLPPPM 847 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLERV 285 DC AL ++M CW + + RP F ++ L+++ Sbjct: 848 DCPAALHQLMLDCWQKDRNSRPRFAEIVNTLDKM 881
>MET_PIG (Q2QLE0) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1381 Score = 65.5 bits (158), Expect = 1e-10 Identities = 31/94 (32%), Positives = 54/94 (57%), Gaps = 1/94 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +WMA E +Q + + K DV+SFG++LWEL+T G P+P++ ++ +G R P Sbjct: 1248 KWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLL-QGRRLLQPE 1306 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLERV 285 C L E+M +CW ++RP F+++ + + Sbjct: 1307 YCPDPLYEVMLKCWHPRAELRPSFSELVSRISAI 1340
>MET_HORSE (Q2QLA9) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1381 Score = 65.5 bits (158), Expect = 1e-10 Identities = 31/94 (32%), Positives = 54/94 (57%), Gaps = 1/94 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +WMA E +Q + + K DV+SFG++LWEL+T G P+P++ ++ +G R P Sbjct: 1248 KWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLL-QGRRLLQPE 1306 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLERV 285 C L E+M +CW ++RP F+++ + + Sbjct: 1307 YCPDPLYEVMLKCWHPKAELRPSFSELVSRISAI 1340
>MET_CALMO (Q2QLC0) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1381 Score = 65.5 bits (158), Expect = 1e-10 Identities = 31/94 (32%), Positives = 54/94 (57%), Gaps = 1/94 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +WMA E +Q + + K DV+SFG++LWEL+T G P+P++ ++ +G R P Sbjct: 1248 KWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLL-QGRRLLQPE 1306 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLERV 285 C L E+M +CW ++RP F+++ + + Sbjct: 1307 YCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAI 1340
>MET_CALJA (Q2QLG5) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1381 Score = 65.5 bits (158), Expect = 1e-10 Identities = 31/94 (32%), Positives = 54/94 (57%), Gaps = 1/94 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +WMA E +Q + + K DV+SFG++LWEL+T G P+P++ ++ +G R P Sbjct: 1248 KWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLL-QGRRLLQPE 1306 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLERV 285 C L E+M +CW ++RP F+++ + + Sbjct: 1307 YCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAI 1340
>MET_PONPY (Q2IBD8) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1390 Score = 65.5 bits (158), Expect = 1e-10 Identities = 31/94 (32%), Positives = 54/94 (57%), Gaps = 1/94 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +WMA E +Q + + K DV+SFG++LWEL+T G P+P++ ++ +G R P Sbjct: 1248 KWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLL-QGRRLLQPE 1306 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLERV 285 C L E+M +CW ++RP F+++ + + Sbjct: 1307 YCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAI 1340
>MET_PANTR (Q2QLF1) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1390 Score = 65.5 bits (158), Expect = 1e-10 Identities = 31/94 (32%), Positives = 54/94 (57%), Gaps = 1/94 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +WMA E +Q + + K DV+SFG++LWEL+T G P+P++ ++ +G R P Sbjct: 1248 KWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLL-QGRRLLQPE 1306 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLERV 285 C L E+M +CW ++RP F+++ + + Sbjct: 1307 YCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAI 1340
>LTK_HUMAN (P29376) Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1)| (Protein tyrosine kinase 1) Length = 864 Score = 65.5 bits (158), Expect = 1e-10 Identities = 35/104 (33%), Positives = 55/104 (52%), Gaps = 3/104 (2%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +WM PE + K D +SFG++LWE+ + G +P+P T + VV G R P Sbjct: 688 KWMPPEAFLEGIFTSKTDSWSFGVLLWEIFSLGYMPYPGRTNQEVLDFVVGGG-RMDPPR 746 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLE--RVEIEVLNNV 261 C + IMT+CW P++RP F + L+ + +VLN++ Sbjct: 747 GCPGPVYRIMTQCWQHEPELRPSFASILERLQYCTQDPDVLNSL 790
>VGFR2_MOUSE (P35918) Vascular endothelial growth factor receptor 2 precursor (EC| 2.7.10.1) (VEGFR-2) (Protein-tyrosine kinase receptor flk-1) (Fetal liver kinase 1) (Kinase NYK) Length = 1367 Score = 65.5 bits (158), Expect = 1e-10 Identities = 31/91 (34%), Positives = 50/91 (54%), Gaps = 1/91 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +WMAPE I R Y + DV+SFG++LWE+ + G P+P + + + +G R P Sbjct: 1068 KWMAPETIFDRVYTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAPD 1127 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARML 294 P + + M CW +P+ RP F+++ L Sbjct: 1128 YTTPEMYQTMLDCWHEDPNQRPSFSELVEHL 1158
>MET_RAT (P97523) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1382 Score = 65.1 bits (157), Expect = 2e-10 Identities = 31/94 (32%), Positives = 54/94 (57%), Gaps = 1/94 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +WMA E +Q + + K DV+SFG++LWEL+T G P+P++ ++ +G R P Sbjct: 1249 KWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITIYLL-QGRRLLQPE 1307 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLERV 285 C AL E+M +CW ++RP +++ + + Sbjct: 1308 YCPDALYEVMLKCWHPKAEMRPSVSELVSRISSI 1341
>LCK_AOTNA (Q5PXS1) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) Length = 508 Score = 65.1 bits (157), Expect = 2e-10 Identities = 34/92 (36%), Positives = 51/92 (55%), Gaps = 1/92 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +W APE I + + K DV+SFGI+L E++T G +P+P MT + + +G R P Sbjct: 404 KWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPE-VIQNLERGYRMVRPD 462 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLE 291 +C L +M CW P+ RP F + +LE Sbjct: 463 NCPEELYHLMMLCWKERPEDRPTFDYLRSVLE 494
>VGFR2_HUMAN (P35968) Vascular endothelial growth factor receptor 2 precursor (EC| 2.7.10.1) (VEGFR-2) (Kinase insert domain receptor) (Protein-tyrosine kinase receptor Flk-1) (CD309 antigen) Length = 1356 Score = 65.1 bits (157), Expect = 2e-10 Identities = 31/91 (34%), Positives = 48/91 (52%), Gaps = 1/91 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +WMAPE I R Y + DV+SFG++LWE+ + G P+P + + + +G R P Sbjct: 1070 KWMAPETIFDRVYTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAPD 1129 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARML 294 P + + M CW P RP F+++ L Sbjct: 1130 YTTPEMYQTMLDCWHGEPSQRPTFSELVEHL 1160
>MUSK_HUMAN (O15146) Muscle, skeletal receptor tyrosine protein kinase precursor| (EC 2.7.10.1) (Muscle-specific tyrosine protein kinase receptor) (Muscle-specific kinase receptor) (MuSK) Length = 869 Score = 65.1 bits (157), Expect = 2e-10 Identities = 35/94 (37%), Positives = 51/94 (54%), Gaps = 1/94 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 RWM PE I + Y + DV+++G+VLWE+ + G P+ M A + V G + P Sbjct: 767 RWMPPESIFYNRYTTESDVWAYGVVLWEIFSYGLQPYYGM-AHEEVIYYVRDGNILSCPE 825 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLERV 285 +C L +M CW P RP FT + R+LER+ Sbjct: 826 NCPVELYNLMRLCWSKLPADRPSFTSIHRILERM 859
>EPHB3_XENLA (Q91735) Ephrin type-B receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor TCK) Length = 974 Score = 65.1 bits (157), Expect = 2e-10 Identities = 32/94 (34%), Positives = 55/94 (58%), Gaps = 1/94 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 RW APE I +R + DV+S+GIV+WE+++ G P+ +M+ Q + + R P Sbjct: 779 RWTAPEAISYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSN-QDVINAIEQDYRLPPPM 837 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLERV 285 DC AL ++M CW + ++RP F+ + L+++ Sbjct: 838 DCPSALHQLMLDCWLRDRNLRPKFSQIVSSLDKL 871
>LTK_MOUSE (P08923) Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1)| Length = 888 Score = 65.1 bits (157), Expect = 2e-10 Identities = 33/95 (34%), Positives = 52/95 (54%), Gaps = 1/95 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +WM PE + + K D +SFG++LWE+ + G +P+P T Q + G R P Sbjct: 684 KWMPPEALLEGLFTSKTDSWSFGVLLWEIFSLGYMPYPGHTN-QEVLDFIATGNRMDPPR 742 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLERVE 282 +C + IMT+CW P++RP F + LER++ Sbjct: 743 NCPGPVYRIMTQCWQHQPELRPDFGSI---LERIQ 774
>EPHA1_MOUSE (Q60750) Ephrin type-A receptor 1 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ESK) Length = 977 Score = 64.7 bits (156), Expect = 2e-10 Identities = 36/94 (38%), Positives = 50/94 (53%), Gaps = 1/94 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 RW APE I HR + DV+SFGIV+WE+++ G P+ M+ Q + G R P Sbjct: 792 RWTAPEAIAHRIFTTASDVWSFGIVMWEVLSFGDKPYGEMSN-QEVMKSIEDGYRLPPPV 850 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLERV 285 DC L E+M CW + RP F + LE++ Sbjct: 851 DCPAPLYELMKNCWAYDRARRPHFLQLQAHLEQL 884
>SRC2_XENLA (P13116) Tyrosine-protein kinase Src-2 (EC 2.7.10.2) (p60-Src-2)| Length = 531 Score = 64.7 bits (156), Expect = 2e-10 Identities = 35/92 (38%), Positives = 51/92 (55%), Gaps = 1/92 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +W APE + + K DV+SFGI+L EL T G +P+P M + V +G R P Sbjct: 425 KWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVN-REVLDQVERGYRMPCPP 483 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLE 291 DC +L ++M +CW +P+ RP F + LE Sbjct: 484 DCPESLHDLMFQCWRKDPEERPTFEYLQAFLE 515
>SRC1_XENLA (P13115) Tyrosine-protein kinase Src-1 (EC 2.7.10.2) (p60-Src-1)| Length = 531 Score = 64.7 bits (156), Expect = 2e-10 Identities = 35/92 (38%), Positives = 51/92 (55%), Gaps = 1/92 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +W APE + + K DV+SFGI+L EL T G +P+P M + V +G R P Sbjct: 425 KWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVN-REVLDQVERGYRMPCPP 483 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLE 291 DC +L ++M +CW +P+ RP F + LE Sbjct: 484 DCPESLHDLMFQCWRKDPEERPTFEYLQAFLE 515
>ERBB_AVIEU (P11273) Tyrosine-protein kinase transforming protein erbB (EC| 2.7.10.1) Length = 540 Score = 64.7 bits (156), Expect = 2e-10 Identities = 33/87 (37%), Positives = 53/87 (60%), Gaps = 1/87 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +WMA E I HR Y + DV+S+G+ +WEL+T G+ P+ + A + + +V+ KG R P Sbjct: 299 KWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEIS-SVLEKGERLPQPP 357 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDV 306 C + IM +CW ++ D RP F ++ Sbjct: 358 ICTIDVYMIMVKCWMSDADSRPKFREL 384
>INSRR_MOUSE (Q9WTL4) Insulin receptor-related protein precursor (EC 2.7.10.1)| (IRR) (IR-related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain] Length = 1300 Score = 64.7 bits (156), Expect = 2e-10 Identities = 36/107 (33%), Positives = 59/107 (55%), Gaps = 1/107 (0%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 RWMAPE ++ + DV+SFG+VLWE++T P+ ++ Q V++ GV + Sbjct: 1157 RWMAPESLKDGIFTTHSDVWSFGVVLWEIVTLAEQPYQGLSNEQVLKFVMDGGVLEEL-E 1215 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLERVEIEVLNNVRKARF 246 +C L E+M CW +P +RP F + L+R++ E+ + R F Sbjct: 1216 NCPIQLQELMRLCWQHSPRLRPTFVHI---LDRIQDELRPSFRLCSF 1259
>KIN16_CAEEL (P34892) Receptor-like tyrosine-protein kinase kin-16 precursor (EC| 2.7.10.1) Length = 495 Score = 64.7 bits (156), Expect = 2e-10 Identities = 31/86 (36%), Positives = 51/86 (59%), Gaps = 1/86 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 RWM+PE + +K DV+SFGI L+E+ T G LP+P++ + + + ++ G R P Sbjct: 365 RWMSPEAFDTMKFTEKSDVWSFGICLYEIFTLGQLPYPDVPS-ERIYEYMHSGRRCPQPQ 423 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTD 309 C L ++M CW P++RP F++ Sbjct: 424 HCHVELYDLMKLCWHEKPELRPNFSN 449
>RYK_AVIR3 (P33497) Tyrosine-protein kinase transforming protein RYK (EC| 2.7.10.1) Length = 442 Score = 64.7 bits (156), Expect = 2e-10 Identities = 33/94 (35%), Positives = 52/94 (55%), Gaps = 1/94 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +W+A E + R Y K DV++FG+ +WE+ T G P+P + + + G R P Sbjct: 223 KWIAIESLADRVYTTKSDVWAFGVTMWEIATRGMTPYPGVQN-HEIYEYLFHGQRLKKPE 281 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLERV 285 +CL L +IM+ CW A P RP F+ + LE++ Sbjct: 282 NCLDELYDIMSSCWRAEPADRPTFSQLKVHLEKL 315
>EPHA3_MOUSE (P29319) Ephrin type-A receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ETK1) (MEK4) Length = 983 Score = 64.7 bits (156), Expect = 2e-10 Identities = 32/94 (34%), Positives = 54/94 (57%), Gaps = 1/94 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 RW +PE + +R + DV+S+GIVLWE+++ G P+ M+ Q V++ R P Sbjct: 789 RWTSPEAMSYRKFTSASDVWSYGIVLWEVMSYGERPYSQMSN-QDVIKAVDERYRLPPPM 847 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLERV 285 DC AL ++M CW + + RP F + +L+++ Sbjct: 848 DCPAALYQLMLDCWQKDRNNRPKFEQIVSILDKL 881
>STK_HYDAT (P17713) Tyrosine-protein kinase STK (EC 2.7.10.2) (P57-STK)| Length = 509 Score = 64.7 bits (156), Expect = 2e-10 Identities = 36/92 (39%), Positives = 52/92 (56%), Gaps = 1/92 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +W APE + + K DV+SFGI++ E++T G +P+P MT Q A V KG R I Sbjct: 401 KWTAPEAALYNRFTIKSDVWSFGILMAEIVTKGRIPYPGMTNAQ-TIAEVEKGYRMPIMP 459 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLE 291 C L IM + W+ +P+ RP F + +LE Sbjct: 460 GCPEPLYNIMLQTWNKDPENRPTFDYLQGVLE 491
>KSYK_HUMAN (P43405) Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine| kinase) Length = 635 Score = 64.3 bits (155), Expect = 3e-10 Identities = 37/125 (29%), Positives = 62/125 (49%), Gaps = 1/125 (0%) Frame = -2 Query: 638 SRLLTSEVARIEVKTEGMTPETGTYRWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTL 462 S+ L ++ + +T G P +W APE I + ++ K DV+SFG+++WE + G Sbjct: 516 SKALRADENYYKAQTHGKWP----VKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQK 571 Query: 461 PFPNMTAVQAAFAVVNKGVRPAIPHDCLPALGEIMTRCWDANPDVRPPFTDVARMLERVE 282 P+ M + A++ KG R P C + ++M CW + + RP F V L Sbjct: 572 PYRGMKGSEVT-AMLEKGERMGCPAGCPREMYDLMNLCWTYDVENRPGFAAVELRLRNYY 630 Query: 281 IEVLN 267 +V+N Sbjct: 631 YDVVN 635
>LIMK1_CHICK (Q8QFP8) LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1) (chLIMK1)| Length = 662 Score = 64.3 bits (155), Expect = 3e-10 Identities = 36/101 (35%), Positives = 54/101 (53%), Gaps = 1/101 (0%) Frame = -2 Query: 572 GTYRWMAPEMIQHRPYNQKVDVYSFGIVLWELITGTLPFPNMTAVQAAFAVVNKG-VRPA 396 G WMAPEMI R Y++KVD++SFGIVL E+I P+ F + +G + Sbjct: 518 GNPYWMAPEMINGRSYDEKVDIFSFGIVLCEIIGRVSADPDYLPRTTDFGLNVRGFLERY 577 Query: 395 IPHDCLPALGEIMTRCWDANPDVRPPFTDVARMLERVEIEV 273 P C P+ I C D +P+ RP F+ + + LE + + + Sbjct: 578 CPPACPPSFFPIAACCCDLDPEKRPSFSKLEQWLETLRMHL 618
>RON_HUMAN (Q04912) Macrophage-stimulating protein receptor precursor (EC| 2.7.10.1) (MSP receptor) (p185-Ron) (CDw136 antigen) [Contains: Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain] Length = 1400 Score = 64.3 bits (155), Expect = 3e-10 Identities = 34/101 (33%), Positives = 58/101 (57%), Gaps = 1/101 (0%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +WMA E +Q + K DV+SFG++LWEL+T G P+ ++ + +G R P Sbjct: 1252 KWMALESLQTYRFTTKSDVWSFGVLLWELLTRGAPPYRHIDPFDLTHFLA-QGRRLPQPE 1310 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLERVEIEVLNN 264 C +L ++M +CW+A+P VRP F + +E++ +L + Sbjct: 1311 YCPDSLYQVMQQCWEADPAVRPTFRVLVGEVEQIVSALLGD 1351
>EPHA1_HUMAN (P21709) Ephrin type-A receptor 1 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EPH) Length = 976 Score = 64.3 bits (155), Expect = 3e-10 Identities = 36/94 (38%), Positives = 50/94 (53%), Gaps = 1/94 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 RW APE I HR + DV+SFGIV+WE+++ G P+ M+ Q + G R P Sbjct: 791 RWTAPEAIAHRIFTTASDVWSFGIVMWEVLSFGDKPYGEMSN-QEVMKSIEDGYRLPPPV 849 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLERV 285 DC L E+M CW + RP F + LE++ Sbjct: 850 DCPAPLYELMKNCWAYDRARRPHFQKLQAHLEQL 883
>CSF1R_RAT (Q00495) Macrophage colony-stimulating factor 1 receptor precursor| (CSF-1-R) (EC 2.7.10.1) (Fms proto-oncogene) (c-fms) Length = 978 Score = 64.3 bits (155), Expect = 3e-10 Identities = 38/121 (31%), Positives = 58/121 (47%), Gaps = 1/121 (0%) Frame = -2 Query: 650 VINRSRLLTSEVARIEVKTEGMTPETGTYRWMAPEMIQHRPYNQKVDVYSFGIVLWELIT 471 ++N S + AR+ VK WMAPE I + Y + DV+S+GI+LWE+ + Sbjct: 801 IMNDSNYVVKGNARLPVK------------WMAPESILYCVYTVQSDVWSYGILLWEIFS 848 Query: 470 -GTLPFPNMTAVQAAFAVVNKGVRPAIPHDCLPALGEIMTRCWDANPDVRPPFTDVARML 294 G P+P + + +V G + A P + IM CWD P RP F + +L Sbjct: 849 LGLNPYPGILVNNKFYKLVKDGYQMAQPVFAPKNIYSIMQSCWDLEPTRRPTFQQICFLL 908 Query: 293 E 291 + Sbjct: 909 Q 909
>YES_CANFA (Q28923) Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2)| (p61-Yes) (c-Yes) Length = 538 Score = 64.3 bits (155), Expect = 3e-10 Identities = 35/92 (38%), Positives = 48/92 (52%), Gaps = 1/92 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +W APE + + K DV+SFGI+ EL T G +P+P M + V +G R P Sbjct: 432 KWTAPEAALYGRFTIKSDVWSFGILQTELTTKGRVPYPGMVN-REVLEQVERGYRMPCPQ 490 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLE 291 C +L E+M CW +PD RP F + LE Sbjct: 491 GCPESLHELMNLCWKKDPDERPTFEYIQSFLE 522
>IGF1R_XENLA (O73798) Insulin-like growth factor 1 receptor precursor (EC| 2.7.10.1) (xIGF-1R) (xIGFR) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain] Length = 1358 Score = 64.3 bits (155), Expect = 3e-10 Identities = 32/87 (36%), Positives = 48/87 (55%), Gaps = 1/87 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 RWM+PE ++ + DV+SFG+VLWE+ T P+ M+ Q V+ G+ P Sbjct: 1173 RWMSPESLKDGVFTTNSDVWSFGVVLWEIATLAEQPYQGMSNEQVLRFVMEGGLLEK-PD 1231 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDV 306 +C L E+M CW NP +RP F ++ Sbjct: 1232 NCPDMLFELMRMCWQFNPKMRPSFLEI 1258
>LCK_MOUSE (P06240) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK) Length = 508 Score = 63.9 bits (154), Expect = 4e-10 Identities = 33/92 (35%), Positives = 51/92 (55%), Gaps = 1/92 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +W APE I + + K DV+SFGI+L E++T G +P+P MT + + +G R P Sbjct: 404 KWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPE-VIQNLERGYRMVRPD 462 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLE 291 +C L +M CW P+ RP F + +L+ Sbjct: 463 NCPEELYHLMMLCWKERPEDRPTFDYLRSVLD 494
>ERBB_ALV (P00534) Tyrosine-protein kinase transforming protein erbB (EC| 2.7.10.1) Length = 634 Score = 63.9 bits (154), Expect = 4e-10 Identities = 33/87 (37%), Positives = 52/87 (59%), Gaps = 1/87 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +WMA E I HR Y + DV+S+G+ +WEL+T G+ P+ + A + + +V+ KG R P Sbjct: 299 KWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEIS-SVLEKGERLPQPP 357 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDV 306 C + IM +CW + D RP F ++ Sbjct: 358 ICTIDVYMIMVKCWMIDADSRPKFREL 384
>ERBB_AVIER (P00535) Tyrosine-protein kinase transforming protein erbB (EC| 2.7.10.1) Length = 604 Score = 63.9 bits (154), Expect = 4e-10 Identities = 33/87 (37%), Positives = 52/87 (59%), Gaps = 1/87 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +WMA E I HR Y + DV+S+G+ +WEL+T G+ P+ + A + + +V+ KG R P Sbjct: 299 KWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEIS-SVLEKGERLPQPP 357 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDV 306 C + IM +CW + D RP F ++ Sbjct: 358 ICTIDVYMIMVKCWMIDADSRPKFREL 384
>EPHB1_CHICK (Q07494) Ephrin type-B receptor 1 (EC 2.7.10.1) (Tyrosine-protein| kinase receptor EPH-2) (Tyrosine kinase CEK6 receptor) (Fragment) Length = 984 Score = 63.9 bits (154), Expect = 4e-10 Identities = 31/94 (32%), Positives = 53/94 (56%), Gaps = 1/94 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 RW APE I +R + DV+S+GIV+WE+++ G P+ +M+ Q + + R P Sbjct: 789 RWTAPEAIAYRKFTSASDVWSYGIVMWEVMSFGERPYWDMSN-QDVINAIEQDYRLPPPM 847 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLERV 285 DC AL ++M CW + + RP ++ L+++ Sbjct: 848 DCPAALHQLMLDCWQKDRNTRPRLAEIVNTLDKM 881
>INSR_XENLA (Q9PVZ4) Insulin receptor precursor (EC 2.7.10.1) (IR) (Xe-InsR)| (XTK-1b) [Contains: Insulin receptor alpha subunit; Insulin receptor beta subunit] Length = 1362 Score = 63.9 bits (154), Expect = 4e-10 Identities = 32/92 (34%), Positives = 51/92 (55%), Gaps = 1/92 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 RWM+PE ++ + DV+SFG+VLWE+ + P+ ++ Q V++ G P Sbjct: 1190 RWMSPESLKDGVFTAFSDVWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGSLDH-PE 1248 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLE 291 +C P L +M CW NP +RP F ++ ML+ Sbjct: 1249 NCPPRLHSLMQMCWQYNPKMRPTFLEIIDMLK 1280
>SRMS_MOUSE (Q62270) Tyrosine-protein kinase Srms (EC 2.7.10.2) (PTK70)| Length = 496 Score = 63.9 bits (154), Expect = 4e-10 Identities = 35/110 (31%), Positives = 58/110 (52%), Gaps = 4/110 (3%) Frame = -2 Query: 602 VKTEGMTPETGT---YRWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQ 435 +K + +P +G+ +W APE +R ++QK DV+SFGI+L+E+ T G P+ MT Sbjct: 379 LKDDVYSPSSGSKIPVKWTAPEAANYRVFSQKSDVWSFGILLYEVFTYGQCPYEGMTN-H 437 Query: 434 AAFAVVNKGVRPAIPHDCLPALGEIMTRCWDANPDVRPPFTDVARMLERV 285 +++G R P C + +M CW +P+ RP F + L + Sbjct: 438 ETLQQISRGYRLPRPAVCPAEVYVLMVECWKGSPEERPTFAILREKLNAI 487
>SRC_AVIST (P14085) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 556 Score = 63.5 bits (153), Expect = 5e-10 Identities = 34/92 (36%), Positives = 51/92 (55%), Gaps = 1/92 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +W APE + + K DV+SFGI+L EL T G +P+P M + V +G R P Sbjct: 426 KWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVN-REVLDQVERGYRMPCPP 484 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLE 291 +C +L ++M +CW +P+ RP F + LE Sbjct: 485 ECPESLHDLMCQCWRKDPEERPTFEYLQAFLE 516
>ABL_DROME (P00522) Tyrosine-protein kinase Abl (EC 2.7.10.2) (Abelson| protein) (D-ash) Length = 1620 Score = 63.5 bits (153), Expect = 5e-10 Identities = 30/94 (31%), Positives = 52/94 (55%), Gaps = 1/94 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +W APE + + ++ K DV++FG++LWE+ T G P+P + + ++KG R P Sbjct: 533 KWTAPEGLAYNKFSTKSDVWAFGVLLWEIATYGMSPYPAIDLTD-VYHKLDKGYRMERPP 591 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLERV 285 C P + ++M +CW + RP F + LE + Sbjct: 592 GCPPEVYDLMRQCWQWDATDRPTFKSIHHALEHM 625
>SRC_AVIS2 (P15054) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 586 Score = 63.5 bits (153), Expect = 5e-10 Identities = 34/92 (36%), Positives = 51/92 (55%), Gaps = 1/92 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +W APE + + K DV+SFGI+L EL T G +P+P M + V +G R P Sbjct: 426 KWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVN-REVLDQVERGYRMPCPP 484 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLE 291 +C +L ++M +CW +P+ RP F + LE Sbjct: 485 ECPESLHDLMCQCWRKDPEERPTFEYLQAFLE 516
>SRC_CHICK (P00523) Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2)| (p60-Src) (c-Src) (pp60c-src) Length = 532 Score = 63.5 bits (153), Expect = 5e-10 Identities = 34/92 (36%), Positives = 51/92 (55%), Gaps = 1/92 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +W APE + + K DV+SFGI+L EL T G +P+P M + V +G R P Sbjct: 426 KWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVN-REVLDQVERGYRMPCPP 484 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLE 291 +C +L ++M +CW +P+ RP F + LE Sbjct: 485 ECPESLHDLMCQCWRKDPEERPTFEYLQAFLE 516
>SRC_AVISS (P14084) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 567 Score = 63.5 bits (153), Expect = 5e-10 Identities = 34/92 (36%), Positives = 51/92 (55%), Gaps = 1/92 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +W APE + + K DV+SFGI+L EL T G +P+P M + V +G R P Sbjct: 426 KWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVN-REVLDQVERGYRMPCPP 484 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLE 291 +C +L ++M +CW +P+ RP F + LE Sbjct: 485 ECPESLHDLMCQCWRKDPEERPTFEYLQAFLE 516
>SRK4_SPOLA (P42690) Tyrosine-protein kinase isoform SRK4 (EC 2.7.10.2)| Length = 506 Score = 63.5 bits (153), Expect = 5e-10 Identities = 36/92 (39%), Positives = 48/92 (52%), Gaps = 1/92 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +W APE + + K DV+SFGIVL+E+IT G P+P MT Q + + R P Sbjct: 400 KWTAPEAAMYSRFTIKSDVWSFGIVLYEVITYGRFPYPGMTNAQ-VLEQIQQSYRMPRPM 458 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLE 291 C L IM CW +P RP F ++ LE Sbjct: 459 GCPEKLYAIMMDCWREDPASRPTFETLSWQLE 490
>EGFR_HUMAN (P00533) Epidermal growth factor receptor precursor (EC 2.7.10.1)| (Receptor tyrosine-protein kinase ErbB-1) Length = 1210 Score = 63.5 bits (153), Expect = 5e-10 Identities = 32/87 (36%), Positives = 52/87 (59%), Gaps = 1/87 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +WMA E I HR Y + DV+S+G+ +WEL+T G+ P+ + A + + +++ KG R P Sbjct: 879 KWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEIS-SILEKGERLPQPP 937 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDV 306 C + IM +CW + D RP F ++ Sbjct: 938 ICTIDVYMIMVKCWMIDADSRPKFREL 964
>RMIL_AVEVR (P27966) Serine/threonine-protein kinase transforming protein Rmil| (EC 2.7.11.1) Length = 450 Score = 63.2 bits (152), Expect = 7e-10 Identities = 35/102 (34%), Positives = 55/102 (53%), Gaps = 7/102 (6%) Frame = -2 Query: 575 TGTYRWMAPEMIQHR---PYNQKVDVYSFGIVLWELITGTLPFPNMTAVQAAFAVVNKGV 405 +G+ WMAPE+I+ + PY+ + DVY+FGIVL+EL+TG LP+ N+ +V +G Sbjct: 240 SGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMVGRGY 299 Query: 404 ----RPAIPHDCLPALGEIMTRCWDANPDVRPPFTDVARMLE 291 + +C A+ +M C D RP F + +E Sbjct: 300 LSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQILASIE 341
>KSYK_RAT (Q64725) Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine| kinase) Length = 629 Score = 63.2 bits (152), Expect = 7e-10 Identities = 37/125 (29%), Positives = 62/125 (49%), Gaps = 1/125 (0%) Frame = -2 Query: 638 SRLLTSEVARIEVKTEGMTPETGTYRWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTL 462 S+ L ++ + +T G P +W APE I + ++ K DV+SFG+++WE + G Sbjct: 510 SKALRADENYYKAQTHGKWP----VKWYAPECINYFKFSSKSDVWSFGVLMWEAFSYGQK 565 Query: 461 PFPNMTAVQAAFAVVNKGVRPAIPHDCLPALGEIMTRCWDANPDVRPPFTDVARMLERVE 282 P+ M + A++ KG R P C + ++M CW + + RP F V L Sbjct: 566 PYRGMKGSEVT-AMLEKGERMGCPPGCPREMYDLMFLCWTYDVENRPGFAAVELRLRNYY 624 Query: 281 IEVLN 267 +V+N Sbjct: 625 YDVVN 629
>SRC_MOUSE (P05480) Neuronal proto-oncogene tyrosine-protein kinase Src (EC| 2.7.10.2) (p60-Src) (c-Src) (pp60c-src) Length = 540 Score = 63.2 bits (152), Expect = 7e-10 Identities = 34/92 (36%), Positives = 50/92 (54%), Gaps = 1/92 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 +W APE + + K DV+SFGI+L EL T G +P+P M + V +G R P Sbjct: 434 KWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVN-REVLDQVERGYRMPCPP 492 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARMLE 291 +C +L ++M +CW P+ RP F + LE Sbjct: 493 ECPESLHDLMCQCWRKEPEERPTFEYLQAFLE 524
>PTK7_CHICK (Q91048) Tyrosine-protein kinase-like 7 precursor (Kinase-like| protein) Length = 1051 Score = 63.2 bits (152), Expect = 7e-10 Identities = 29/91 (31%), Positives = 50/91 (54%), Gaps = 1/91 (1%) Frame = -2 Query: 563 RWMAPEMIQHRPYNQKVDVYSFGIVLWELIT-GTLPFPNMTAVQAAFAVVNKGVRPAIPH 387 RWM PE + ++ K DV+SFG+++WE+ T G +P+ + + + + + P Sbjct: 952 RWMPPEAVLEDEFSTKSDVWSFGVLMWEVFTQGEMPYAPLADDEVLAGLKSGKTKLPQPE 1011 Query: 386 DCLPALGEIMTRCWDANPDVRPPFTDVARML 294 C L ++M RCW +P RP F+++A L Sbjct: 1012 GCPSRLTKLMQRCWAPSPKDRPSFSELAAAL 1042
>BRAF1_HUMAN (P15056) B-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (p94) (v-Raf murine sarcoma viral oncogene homolog B1) Length = 766 Score = 63.2 bits (152), Expect = 7e-10 Identities = 35/102 (34%), Positives = 55/102 (53%), Gaps = 7/102 (6%) Frame = -2 Query: 575 TGTYRWMAPEMIQHR---PYNQKVDVYSFGIVLWELITGTLPFPNMTAVQAAFAVVNKGV 405 +G+ WMAPE+I+ + PY+ + DVY+FGIVL+EL+TG LP+ N+ +V +G Sbjct: 614 SGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMVGRGY 673 Query: 404 ----RPAIPHDCLPALGEIMTRCWDANPDVRPPFTDVARMLE 291 + +C A+ +M C D RP F + +E Sbjct: 674 LSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQILASIE 715
>BRAF1_MOUSE (P28028) B-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (Fragment) Length = 328 Score = 63.2 bits (152), Expect = 7e-10 Identities = 35/102 (34%), Positives = 55/102 (53%), Gaps = 7/102 (6%) Frame = -2 Query: 575 TGTYRWMAPEMIQHR---PYNQKVDVYSFGIVLWELITGTLPFPNMTAVQAAFAVVNKGV 405 +G+ WMAPE+I+ + PY+ + DVY+FGIVL+EL+TG LP+ N+ +V +G Sbjct: 176 SGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMVGRGY 235 Query: 404 ----RPAIPHDCLPALGEIMTRCWDANPDVRPPFTDVARMLE 291 + +C A+ +M C D RP F + +E Sbjct: 236 LSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQILASIE 277
>BRAF1_CHICK (Q04982) B-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (Rmil serine/threonine-protein kinase) (c-Rmil) Length = 806 Score = 63.2 bits (152), Expect = 7e-10 Identities = 35/102 (34%), Positives = 55/102 (53%), Gaps = 7/102 (6%) Frame = -2 Query: 575 TGTYRWMAPEMIQHR---PYNQKVDVYSFGIVLWELITGTLPFPNMTAVQAAFAVVNKGV 405 +G+ WMAPE+I+ + PY+ + DVY+FGIVL+EL+TG LP+ N+ +V +G Sbjct: 654 SGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMVGRGY 713 Query: 404 ----RPAIPHDCLPALGEIMTRCWDANPDVRPPFTDVARMLE 291 + +C A+ +M C D RP F + +E Sbjct: 714 LSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQILASIE 755
>RMIL_AVII1 (P10533) Serine/threonine-protein kinase transforming protein Rmil| (EC 2.7.11.1) Length = 367 Score = 63.2 bits (152), Expect = 7e-10 Identities = 35/102 (34%), Positives = 55/102 (53%), Gaps = 7/102 (6%) Frame = -2 Query: 575 TGTYRWMAPEMIQHR---PYNQKVDVYSFGIVLWELITGTLPFPNMTAVQAAFAVVNKGV 405 +G+ WMAPE+I+ + PY+ + DVY+FGIVL+EL+TG LP+ N+ +V +G Sbjct: 224 SGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMVGRGY 283 Query: 404 ----RPAIPHDCLPALGEIMTRCWDANPDVRPPFTDVARMLE 291 + +C A+ +M C D RP F + +E Sbjct: 284 LSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQILASIE 325 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 98,059,395 Number of Sequences: 219361 Number of extensions: 2149988 Number of successful extensions: 8529 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 7572 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 8042 length of database: 80,573,946 effective HSP length: 108 effective length of database: 56,882,958 effective search space used: 6200242422 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
