ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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更新日:2016年5月1日

Clone Information

BLAST Search Result

Clone Name rbags9k10
Clone Library Name barley_pub

No. Definition Score
(bits)
E
Value
1SUVH6_ARATH (Q8VZ17) Histone-lysine N-methyltransferase, H3 lysi... 260 3e-69
2SUVH5_ARATH (O82175) Histone-lysine N-methyltransferase, H3 lysi... 245 9e-65
3SUVH4_ARATH (Q8GZB6) Histone-lysine N-methyltransferase, H3 lysi... 175 1e-43
4SUVH1_ARATH (Q9FF80) Histone-lysine N-methyltransferase, H3 lysi... 157 4e-38
5SUVH3_ARATH (Q9C5P4) Histone-lysine N-methyltransferase, H3 lysi... 157 4e-38
6SUVH9_ARATH (Q9T0G7) Probable histone-lysine N-methyltransferase... 142 1e-33
7EHMT2_MOUSE (Q9Z148) Histone-lysine N-methyltransferase, H3 lysi... 139 1e-32
8EHMT2_HUMAN (Q96KQ7) Histone-lysine N-methyltransferase, H3 lysi... 138 2e-32
9EHMT1_HUMAN (Q9H9B1) Histone-lysine N-methyltransferase, H3 lysi... 137 4e-32
10SUVH7_ARATH (Q9C5P1) Histone-lysine N-methyltransferase, H3 lysi... 134 3e-31
11SUVR5_ARATH (O64827) Histone-lysine N-methyltransferase SUVR5 (E... 134 3e-31
12SUV91_MOUSE (O54864) Histone-lysine N-methyltransferase, H3 lysi... 132 1e-30
13SUVH2_ARATH (O22781) Histone-lysine N-methyltransferase, H3 lysi... 132 1e-30
14SUV91_HUMAN (O43463) Histone-lysine N-methyltransferase, H3 lysi... 131 2e-30
15CLR4_SCHPO (O60016) Histone-lysine N-methyltransferase, H3 lysin... 130 5e-30
16DIM5_NEUCR (Q8X225) Histone-lysine N-methyltransferase, H3 lysin... 122 9e-28
17SUV92_HUMAN (Q9H5I1) Histone-lysine N-methyltransferase, H3 lysi... 122 1e-27
18SUV92_MOUSE (Q9EQQ0) Histone-lysine N-methyltransferase, H3 lysi... 122 1e-27
19SUVH8_ARATH (Q9C5P0) Histone-lysine N-methyltransferase, H3 lysi... 119 1e-26
20SUV9_DROME (P45975) Histone-lysine N-methyltransferase, H3 lysin... 112 9e-25
21SUVR4_ARATH (Q8W595) Histone-lysine N-methyltransferase SUVR4 (E... 101 3e-21
22SUVR1_ARATH (Q946J2) Histone-lysine N-methyltransferase SUVR1 (E... 95 2e-19
23NSD1_HUMAN (Q96L73) Histone-lysine N-methyltransferase, H3 lysin... 92 2e-18
24ASHH1_ARATH (Q84WW6) Histone-lysine N-methyltransferase ASHH1 (E... 92 2e-18
25NSD1_MOUSE (O88491) Histone-lysine N-methyltransferase, H3 lysin... 91 4e-18
26SETB1_MOUSE (O88974) Histone-lysine N-methyltransferase, H3 lysi... 91 5e-18
27MES4_DROME (Q8MT36) Probable histone methyltransferase Mes-4 (Ma... 91 5e-18
28ASHR3_ARATH (Q949T8) Histone-lysine N-methyltransferase ASHR3 pr... 90 6e-18
29SETB1_HUMAN (Q15047) Histone-lysine N-methyltransferase, H3 lysi... 90 6e-18
30SUVR2_ARATH (Q9FNC7) Histone-lysine N-methyltransferase SUVR2 (E... 88 2e-17
31ASHH2_ARATH (Q2LAE1) Histone-lysine N-methyltransferase, H3 lysi... 87 5e-17
32ASHH4_ARATH (Q9M1X9) Putative histone-lysine N-methyltransferase... 81 3e-15
33ASHH3_ARATH (Q945S8) Histone-lysine N-methyltransferase ASHH3 (E... 80 5e-15
34MES4_CAEEL (Q9NH52) Probable histone methyltransferase mes-4 (Ma... 80 6e-15
35SET2_YEAST (P46995) SET domain protein 2 77 7e-14
36SET2_CAEEL (Q18221) Protein set-2 75 3e-13
37SETB2_HUMAN (Q96T68) Probable histone-lysine N-methyltransferase... 70 7e-12
38EZ_DROME (P42124) Polycomb protein E(z) (Protein enhancer of zeste) 70 9e-12
39YNCA_CAEEL (P34544) Hypothetical protein R05D3.11 in chromosome III 69 1e-11
40TRX_DROVI (Q24742) Protein trithorax 69 1e-11
41EZH2_HUMAN (Q15910) Enhancer of zeste homolog 2 (ENX-1) 69 1e-11
42EZH1_MOUSE (P70351) Enhancer of zeste homolog 1 (ENX-2) 69 1e-11
43EZH1_HUMAN (Q92800) Enhancer of zeste homolog 1 (ENX-2) 69 1e-11
44SUVR3_ARATH (Q9SRV2) Histone-lysine N-methyltransferase SUVR3 (E... 68 3e-11
45TRX_DROME (P20659) Protein trithorax 67 4e-11
46EZH2_MOUSE (Q61188) Enhancer of zeste homolog 2 (ENX-1) 67 6e-11
47MLL2_HUMAN (O14686) Myeloid/lymphoid or mixed-lineage leukemia p... 66 1e-10
48HRX_HUMAN (Q03164) Zinc finger protein HRX (ALL-1) (Trithorax-li... 66 1e-10
49HRX_MOUSE (P55200) Zinc finger protein HRX (ALL-1) (Fragment) 66 1e-10
50SET1_SCHPO (Q9Y7R4) Histone-lysine N-methyltransferase, H3 lysin... 65 2e-10
51SET1A_HUMAN (O15047) Histone-lysine N-methyltransferase, H3 lysi... 65 3e-10
52SET1_YEAST (P38827) Histone-lysine N-methyltransferase, H3 lysin... 62 2e-09
53ATX4_ARATH (Q9SUE7) Histone-lysine N-methyltransferase ATX4 (EC ... 61 4e-09
54MEDEA_ARATH (O65312) Polycomb group protein MEDEA (Maternal embr... 60 9e-09
55SUVHA_ARATH (Q3EC60) Putative histone-lysine N-methyltransferase... 60 9e-09
56MLL3_HUMAN (Q8NEZ4) Myeloid/lymphoid or mixed-lineage leukemia p... 59 1e-08
57MLL3_MOUSE (Q8BRH4) Myeloid/lymphoid or mixed-lineage leukemia p... 59 2e-08
58MLL4_HUMAN (Q9UMN6) Myeloid/lymphoid or mixed-lineage leukemia p... 57 4e-08
59ATX1_ARATH (Q9C5X4) Histone-lysine N-methyltransferase, H3 lysin... 56 1e-07
60ATX2_ARATH (Q9MA43) Histone-lysine N-methyltransferase ATX2 (EC ... 55 2e-07
61ATX5_ARATH (Q8GZ42) Histone-lysine N-methyltransferase ATX5 (EC ... 55 2e-07
62EZA1_ARATH (Q9ZSM8) Probable Polycomb group protein EZA1 (CURLY ... 55 3e-07
63MES2_CAEEL (O17514) Polycomb protein mes-2 (Maternal-effect ster... 54 5e-07
64EZ1_MAIZE (Q8S4P6) Polycomb protein EZ1 (Enhancer of zeste prote... 54 5e-07
65EZ2_MAIZE (Q8S4P5) Polycomb protein EZ2 (Enhancer of zeste prote... 53 8e-07
66EZ3_MAIZE (Q8S4P4) Polycomb protein EZ3 (Enhancer of zeste prote... 53 8e-07
67CLF_ARATH (P93831) Polycomb group protein CURLY LEAF (Protein IN... 52 1e-06
68LIN59_CAEEL (O44757) Protein lin-59 (Abnormal cell lineage prote... 52 2e-06
69SETD8_DROME (Q9VFK6) Histone-lysine N-methyltransferase, H4 lysi... 44 5e-04
70SETD8_BOVIN (Q2YDJ8) Histone-lysine N-methyltransferase, H4 lysi... 44 7e-04
71SETD8_HUMAN (Q9NQR1) Histone-lysine N-methyltransferase, H4 lysi... 44 7e-04
72SETD8_MOUSE (Q2YDW7) Histone-lysine N-methyltransferase, H4 lysi... 42 0.001
73YL222_MIMIV (Q5UQB9) Hypothetical SET domain-containing protein ... 38 0.028
74SET1_CAEEL (Q22795) Protein set-1 38 0.037
75ATX3_ARATH (Q9M364) Histone-lysine N-methyltransferase ATX3 (EC ... 35 0.24
76ATXR3_ARATH (O23372) Probable histone-lysine N-methyltransferase... 34 0.53
77EFG1_BURPS (Q63WJ7) Elongation factor G 1 (EF-G 1) 31 3.4
78EFG1_BURP1 (Q3JV86) Elongation factor G 1 (EF-G 1) 31 3.4
79EFG1_BURMA (Q62HK4) Elongation factor G 1 (EF-G 1) 31 3.4
80BGAL_BACST (P19668) Beta-galactosidase 1 (EC 3.2.1.23) (Beta-gal... 30 5.8
81PRDM4_MOUSE (Q80V63) PR domain zinc finger protein 4 (PR domain-... 30 7.6
82Y871_RICPR (Q9ZC95) Hypothetical protein RP871 30 7.6
83YL678_MIMIV (Q5UNT8) Hypothetical SET domain protein L678 30 7.6
84RM18_MOUSE (Q9CQL5) 39S ribosomal protein L18, mitochondrial pre... 30 7.6
85FDXG_HAEIN (P46448) Formate dehydrogenase major subunit (EC 1.2.... 30 10.0

>SUVH6_ARATH (Q8VZ17) Histone-lysine N-methyltransferase, H3 lysine-9 specific|
            SUVH6 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 6)
            (H3-K9-HMTase 6) (Suppressor of variegation 3-9 homolog
            protein 6) (Su(var)3-9 homolog protein 6) (Protein SET
            DOMAIN GR
          Length = 790

 Score =  260 bits (664), Expect = 3e-69
 Identities = 123/214 (57%), Positives = 153/214 (71%), Gaps = 4/214 (1%)
 Frame = -1

Query: 730  PFNDMGRIIEAKPLVYECGPSCKCPPTCHNRVGQKGIKFRLQVFKTKSMGWGVKTLDYIP 551
            P+N  G I+ AKP +YECGP CKCP +C+ RV Q GIK  L++FKTKS GWGV+ L  IP
Sbjct: 578  PYNFDGAIVGAKPTIYECGPLCKCPSSCYLRVTQHGIKLPLEIFKTKSRGWGVRCLKSIP 637

Query: 550  SGSFVCEYIGEVLDDEEAQKRM-TDEYLFAIGHNYYDETLWEGLSRSIPSLQNGPG---N 383
             GSF+CEY+GE+L+D EA++R+  DEYLF IG N YD +L +G+S  +   Q G      
Sbjct: 638  IGSFICEYVGELLEDSEAERRIGNDEYLFDIG-NRYDNSLAQGMSELMLGTQAGRSMAEG 696

Query: 382  DEEAGFAVDASKMGNFAKFINHSCTPNLYAQNALYDHDDKSAPHIMFFACENIPPGQELV 203
            DE +GF +DA+  GN  +FINHSC+PNLYAQN LYDH+D   PH+MFFA +NIPP QEL 
Sbjct: 697  DESSGFTIDAASKGNVGRFINHSCSPNLYAQNVLYDHEDSRIPHVMFFAQDNIPPLQELC 756

Query: 202  YHYNYAIDQVYDENGNIKKKKCLCGSTECDGWLY 101
            Y YNYA+DQV D  GNIK+K C CG+  C   LY
Sbjct: 757  YDYNYALDQVRDSKGNIKQKPCFCGAAVCRRRLY 790



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>SUVH5_ARATH (O82175) Histone-lysine N-methyltransferase, H3 lysine-9 specific|
            SUVH5 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 5)
            (H3-K9-HMTase 5) (Suppressor of variegation 3-9 homolog
            protein 5) (Su(var)3-9 homolog protein 5) (Protein SET
            DOMAIN GR
          Length = 794

 Score =  245 bits (626), Expect = 9e-65
 Identities = 117/211 (55%), Positives = 146/211 (69%), Gaps = 1/211 (0%)
 Frame = -1

Query: 730  PFNDMGRIIEAKPLVYECGPSCKCPPTCHNRVGQKGIKFRLQVFKTKSMGWGVKTLDYIP 551
            P+ D G I+E KPLVYECGP CKCPP+C+ RV Q GIK +L++FKT+S GWGV++L+ IP
Sbjct: 610  PYYD-GAIVEIKPLVYECGPHCKCPPSCNMRVSQHGIKIKLEIFKTESRGWGVRSLESIP 668

Query: 550  SGSFVCEYIGEVLDDEEAQKRM-TDEYLFAIGHNYYDETLWEGLSRSIPSLQNGPGNDEE 374
             GSF+CEY GE+L+D++A+     DEYLF +G                         DE+
Sbjct: 669  IGSFICEYAGELLEDKQAESLTGKDEYLFDLG-------------------------DED 703

Query: 373  AGFAVDASKMGNFAKFINHSCTPNLYAQNALYDHDDKSAPHIMFFACENIPPGQELVYHY 194
              F ++A++ GN  +FINHSC+PNLYAQ+ LYDH++   PHIMFFA +NIPP QEL Y Y
Sbjct: 704  DPFTINAAQKGNIGRFINHSCSPNLYAQDVLYDHEEIRIPHIMFFALDNIPPLQELSYDY 763

Query: 193  NYAIDQVYDENGNIKKKKCLCGSTECDGWLY 101
            NY IDQVYD NGNIKKK C CGS EC G LY
Sbjct: 764  NYKIDQVYDSNGNIKKKFCYCGSAECSGRLY 794



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>SUVH4_ARATH (Q8GZB6) Histone-lysine N-methyltransferase, H3 lysine-9 specific|
            SUVH4 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 4)
            (H3-K9-HMTase 4) (Suppressor of variegation 3-9 homolog
            protein 4) (Su(var)3-9 homolog protein 4) (Protein
            KRYPTONITE) (
          Length = 624

 Score =  175 bits (444), Expect = 1e-43
 Identities = 92/220 (41%), Positives = 127/220 (57%), Gaps = 10/220 (4%)
 Frame = -1

Query: 730  PFNDM--GRIIEAKPLVYECGPSCKCPPTCHNRVGQKGIKFRLQVFKTKSMGWGVKTLDY 557
            P+ D+  GR+IE++ +V+ECGP C C P C NR  QK ++F L+VF++   GW V++ +Y
Sbjct: 406  PYVDLNDGRLIESRDVVFECGPHCGCGPKCVNRTSQKRLRFNLEVFRSAKKGWAVRSWEY 465

Query: 556  IPSGSFVCEYIGEVLDDEEAQKRMTDEYLFAIGHNYYDETLWEGLSR----SIPSLQNG- 392
            IP+GS VCEYIG V    +      +EY+F I      + L     R    ++P + NG 
Sbjct: 466  IPAGSPVCEYIGVVRRTADVDTISDNEYIFEIDCQQTMQGLGGRQRRLRDVAVP-MNNGV 524

Query: 391  --PGNDEEAG-FAVDASKMGNFAKFINHSCTPNLYAQNALYDHDDKSAPHIMFFACENIP 221
                 DE A  F +DA   GNFA+FINHSC PNL+ Q  L  H D     ++ FA +NI 
Sbjct: 525  SQSSEDENAPEFCIDAGSTGNFARFINHSCEPNLFVQCVLSSHQDIRLARVVLFAADNIS 584

Query: 220  PGQELVYHYNYAIDQVYDENGNIKKKKCLCGSTECDGWLY 101
            P QEL Y Y YA+D V+  +G +K+  C CG+  C   LY
Sbjct: 585  PMQELTYDYGYALDSVHGPDGKVKQLACYCGALNCRKRLY 624



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>SUVH1_ARATH (Q9FF80) Histone-lysine N-methyltransferase, H3 lysine-9 specific|
            SUVH1 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 1)
            (H3-K9-HMTase 1) (Suppressor of variegation 3-9 homolog
            protein 1) (Su(var)3-9 homolog protein 1) (Protein SET
            DOMAIN GR
          Length = 670

 Score =  157 bits (396), Expect = 4e-38
 Identities = 82/213 (38%), Positives = 121/213 (56%), Gaps = 6/213 (2%)
 Frame = -1

Query: 730  PFNDMGRIIEAKPLVYECGPSCKCPPTCHNRVGQKGIKFRLQVFKTKSMGWGVKTLDYIP 551
            P+   G ++  KP++YEC PSC C  TC N+V Q G+K RL+VFKT + GWG+++ D I 
Sbjct: 458  PYTGNGILVSRKPMIYECSPSCPCS-TCKNKVTQMGVKVRLEVFKTANRGWGLRSWDAIR 516

Query: 550  SGSFVCEYIGEVLDDEEAQKRM-TDEYLFAIGHNYYDETLWE---GLSRSIPSLQNGPGN 383
            +GSF+C Y+GE  D  + Q+ M  D+Y F    N Y+   W    GL+      +    +
Sbjct: 517  AGSFICIYVGEAKDKSKVQQTMANDDYTFDT-TNVYNPFKWNYEPGLADEDACEEMSEES 575

Query: 382  DEEAGFAVDASKMGNFAKFINHSCTPNLYAQNALYDHDDKSAPHIMFFACENIPPGQELV 203
            +      + A  +GN A+F+NHSC+PN++ Q   Y+++ +   H+ FFA  +IPP  EL 
Sbjct: 576  EIPLPLIISAKNVGNVARFMNHSCSPNVFWQPVSYENNSQLFVHVAFFAISHIPPMTELT 635

Query: 202  YHYNYAIDQVYDENGN--IKKKKCLCGSTECDG 110
            Y Y  +      +NGN    K+KC CGS  C G
Sbjct: 636  YDYGVSRPS-GTQNGNPLYGKRKCFCGSAYCRG 667



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>SUVH3_ARATH (Q9C5P4) Histone-lysine N-methyltransferase, H3 lysine-9 specific|
            SUVH3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3)
            (H3-K9-HMTase 3) (Suppressor of variegation 3-9 homolog
            protein 3) (Su(var)3-9 homolog protein 3) (Protein SET
            DOMAIN GR
          Length = 669

 Score =  157 bits (396), Expect = 4e-38
 Identities = 81/209 (38%), Positives = 121/209 (57%), Gaps = 9/209 (4%)
 Frame = -1

Query: 709  IIEAKPLVYECGPSCKCPPTCHNRVGQKGIKFRLQVFKTKSMGWGVKTLDYIPSGSFVCE 530
            ++  +P++YECGP+C C  +C NRV Q G+K RL+VFKT++ GWG+++ D + +GSF+CE
Sbjct: 463  LVSRRPVIYECGPTCPCHASCKNRVIQTGLKSRLEVFKTRNRGWGLRSWDSLRAGSFICE 522

Query: 529  YIGEVLD--------DEEAQKRMTDEYLFAIGHNYYDETLWEGLSRSIPSLQNGPGNDEE 374
            Y GEV D        +E+A    T     +   NY  E + E  S  +P   N P     
Sbjct: 523  YAGEVKDNGNLRGNQEEDAYVFDTSRVFNSFKWNYEPELVDEDPSTEVPEEFNLP----- 577

Query: 373  AGFAVDASKMGNFAKFINHSCTPNLYAQNALYDHDDKSAPHIMFFACENIPPGQELVYHY 194
            +   + A K GN A+F+NHSC+PN++ Q  + + + +S  HI FFA  +IPP  EL Y Y
Sbjct: 578  SPLLISAKKFGNVARFMNHSCSPNVFWQPVIREGNGESVIHIAFFAMRHIPPMAELTYDY 637

Query: 193  NYA-IDQVYDENGNIKKKKCLCGSTECDG 110
              +   +  DE+    ++ CLCGS +C G
Sbjct: 638  GISPTSEARDESLLHGQRTCLCGSEQCRG 666



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>SUVH9_ARATH (Q9T0G7) Probable histone-lysine N-methyltransferase, H3 lysine-9|
            specific SUVH9 (EC 2.1.1.43) (Histone H3-K9
            methyltransferase 9) (H3-K9-HMTase 9) (Suppressor of
            variegation 3-9 homolog protein 9) (Su(var)3-9 homolog
            protein 9) (Protein SET
          Length = 650

 Score =  142 bits (357), Expect = 1e-33
 Identities = 73/182 (40%), Positives = 104/182 (57%), Gaps = 3/182 (1%)
 Frame = -1

Query: 715  GRIIEAKPLVYECGPSCKCPPTCHNRVGQKGIKFRLQVFKTKSMGWGVKTLDYIPSGSFV 536
            G +I  KPL++ECG +C+CPP+C NRV QKG++ RL+VF++   GWGV++LD + +G+F+
Sbjct: 460  GTLIRQKPLIHECGSACQCPPSCRNRVTQKGLRNRLEVFRSLETGWGVRSLDVLHAGAFI 519

Query: 535  CEYIGEVLDDEEAQ--KRMTDEYLFAIGHNYYDETLWEGLSRSIPSLQNGPGND-EEAGF 365
            CEY G  L  E+A       D  ++    +      W  LS+ +   +     D     F
Sbjct: 520  CEYAGVALTREQANILTMNGDTLVYPARFSSARWEDWGDLSQVLADFERPSYPDIPPVDF 579

Query: 364  AVDASKMGNFAKFINHSCTPNLYAQNALYDHDDKSAPHIMFFACENIPPGQELVYHYNYA 185
            A+D SKM N A +I+HS  PN+  Q  L+DH+    P +M FA ENIPP  EL   Y   
Sbjct: 580  AMDVSKMRNVACYISHSTDPNVIVQFVLHDHNSLMFPRVMLFAAENIPPMTELSLDYGVV 639

Query: 184  ID 179
             D
Sbjct: 640  DD 641



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>EHMT2_MOUSE (Q9Z148) Histone-lysine N-methyltransferase, H3 lysine-9 specific 3|
            (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3)
            (H3-K9-HMTase 3) (Euchromatic histone-lysine
            N-methyltransferase 2) (HLA-B-associated transcript 8)
            (Protein G9a)
          Length = 1263

 Score =  139 bits (349), Expect = 1e-32
 Identities = 74/195 (37%), Positives = 101/195 (51%), Gaps = 2/195 (1%)
 Frame = -1

Query: 694  PLVYECGPSCKCPPTCHNRVGQKGIKFRLQVFKTKSMGWGVKTLDYIPSGSFVCEYIGEV 515
            PL++EC  +C C  +C NRV Q GIK RLQ+++T  MGWGV+ L  IP G+F+CEY+GE+
Sbjct: 1065 PLIFECNQACSCWRSCKNRVVQSGIKVRLQLYRTAKMGWGVRALQTIPQGTFICEYVGEL 1124

Query: 514  LDDEEAQKRMTDEYLFAIGHNYYDETLWEGLSRSIPSLQNGPGNDEEAGFAVDASKMGNF 335
            + D EA  R  D YLF +                         N +   + +DA   GN 
Sbjct: 1125 ISDAEADVREDDSYLFDL------------------------DNKDGEVYCIDARYYGNI 1160

Query: 334  AKFINHSCTPNLYAQNALYDHDDKSAPHIMFFACENIPPGQELVYHYNYAIDQVYDENGN 155
            ++FINH C PN+        H D   P I FF+  +I  G+EL + Y    D+ +D    
Sbjct: 1161 SRFINHLCDPNIIPVRVFMLHQDLRFPRIAFFSSRDIRTGEELGFDYG---DRFWD---- 1213

Query: 154  IKKK--KCLCGSTEC 116
            IK K   C CGS +C
Sbjct: 1214 IKSKYFTCQCGSEKC 1228



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>EHMT2_HUMAN (Q96KQ7) Histone-lysine N-methyltransferase, H3 lysine-9 specific 3|
            (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3)
            (H3-K9-HMTase 3) (Euchromatic histone-lysine
            N-methyltransferase 2) (HLA-B-associated transcript 8)
            (Protein G9a)
          Length = 1210

 Score =  138 bits (348), Expect = 2e-32
 Identities = 74/195 (37%), Positives = 100/195 (51%), Gaps = 2/195 (1%)
 Frame = -1

Query: 694  PLVYECGPSCKCPPTCHNRVGQKGIKFRLQVFKTKSMGWGVKTLDYIPSGSFVCEYIGEV 515
            PL++EC  +C C   C NRV Q GIK RLQ+++T  MGWGV+ L  IP G+F+CEY+GE+
Sbjct: 1012 PLIFECNQACSCWRNCKNRVVQSGIKVRLQLYRTAKMGWGVRALQTIPQGTFICEYVGEL 1071

Query: 514  LDDEEAQKRMTDEYLFAIGHNYYDETLWEGLSRSIPSLQNGPGNDEEAGFAVDASKMGNF 335
            + D EA  R  D YLF +                         N +   + +DA   GN 
Sbjct: 1072 ISDAEADVREDDSYLFDL------------------------DNKDGEVYCIDARYYGNI 1107

Query: 334  AKFINHSCTPNLYAQNALYDHDDKSAPHIMFFACENIPPGQELVYHYNYAIDQVYDENGN 155
            ++FINH C PN+        H D   P I FF+  +I  G+EL + Y    D+ +D    
Sbjct: 1108 SRFINHLCDPNIIPVRVFMLHQDLRFPRIAFFSSRDIRTGEELGFDYG---DRFWD---- 1160

Query: 154  IKKK--KCLCGSTEC 116
            IK K   C CGS +C
Sbjct: 1161 IKSKYFTCQCGSEKC 1175



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>EHMT1_HUMAN (Q9H9B1) Histone-lysine N-methyltransferase, H3 lysine-9 specific 5|
            (EC 2.1.1.43) (Histone H3-K9 methyltransferase 5)
            (H3-K9-HMTase 5) (Euchromatic histone-lysine
            N-methyltransferase 1) (Eu-HMTase1) (G9a-like protein 1)
            (GLP1)
          Length = 1267

 Score =  137 bits (344), Expect = 4e-32
 Identities = 71/193 (36%), Positives = 100/193 (51%)
 Frame = -1

Query: 694  PLVYECGPSCKCPPTCHNRVGQKGIKFRLQVFKTKSMGWGVKTLDYIPSGSFVCEYIGEV 515
            PL++EC  +C C   C NRV Q G++ RLQ+++T+ MGWGV++L  IP G+FVCEY+GE+
Sbjct: 1069 PLIFECNHACSCWRNCRNRVVQNGLRARLQLYRTRDMGWGVRSLQDIPPGTFVCEYVGEL 1128

Query: 514  LDDEEAQKRMTDEYLFAIGHNYYDETLWEGLSRSIPSLQNGPGNDEEAGFAVDASKMGNF 335
            + D EA  R  D YLF +                         N +   + +DA   GN 
Sbjct: 1129 ISDSEADVREEDSYLFDL------------------------DNKDGEVYCIDARFYGNV 1164

Query: 334  AKFINHSCTPNLYAQNALYDHDDKSAPHIMFFACENIPPGQELVYHYNYAIDQVYDENGN 155
            ++FINH C PNL        H D   P I FF+   I  G++L + Y    ++ +D  G 
Sbjct: 1165 SRFINHHCEPNLVPVRVFMAHQDLRFPRIAFFSTRLIEAGEQLGFDYG---ERFWDIKG- 1220

Query: 154  IKKKKCLCGSTEC 116
             K   C CGS +C
Sbjct: 1221 -KLFSCRCGSPKC 1232



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>SUVH7_ARATH (Q9C5P1) Histone-lysine N-methyltransferase, H3 lysine-9 specific|
            SUVH7 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 7)
            (H3-K9-HMTase 7) (Suppressor of variegation 3-9 homolog
            protein 7) (Su(var)3-9 homolog protein 7) (Protein SET
            DOMAIN GR
          Length = 693

 Score =  134 bits (337), Expect = 3e-31
 Identities = 76/206 (36%), Positives = 110/206 (53%), Gaps = 10/206 (4%)
 Frame = -1

Query: 697  KPLVYECGPSCKCPPTCHNRVGQKGIKFRLQVFKTKSMGWGVKTLDYIPSGSFVCEYIGE 518
            KPL+YECG SC CP  C  R+ Q G+K  L+VFKT++ GWG+++ D I +G+F+CE+ G 
Sbjct: 492  KPLIYECGGSCPCPDHCPTRLVQTGLKLHLEVFKTRNCGWGLRSWDPIRAGTFICEFAGL 551

Query: 517  VLDDEEAQKRMTDEYLFAIGH-------NYYDETLWEGLSRSIPSLQNGPGNDEEAGFAV 359
                EE ++   D+YLF           NY  E L E     +    N P         +
Sbjct: 552  RKTKEEVEE--DDDYLFDTSKIYQRFRWNYEPELLLEDSWEQVSEFINLP-----TQVLI 604

Query: 358  DASKMGNFAKFINHSCTPNLYAQNALYDHDDKSAPHIMFFACENIPPGQELVYHYNYAID 179
             A + GN  +F+NHSC+PN++ Q   Y++       I  FA ++IPP  EL Y Y  +  
Sbjct: 605  SAKEKGNVGRFMNHSCSPNVFWQPIEYENRGDVYLLIGLFAMKHIPPMTELTYDYGVSCV 664

Query: 178  QVYDENGNI---KKKKCLCGSTECDG 110
            +  +E+  +    KK CLCGS +C G
Sbjct: 665  ERSEEDEVLLYKGKKTCLCGSVKCRG 690



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>SUVR5_ARATH (O64827) Histone-lysine N-methyltransferase SUVR5 (EC 2.1.1.43)|
           (Suppressor of variegation 3-9-related protein 5)
           (Su(var)3-9-related protein 5) (Protein SET DOMAIN GROUP
           6)
          Length = 203

 Score =  134 bits (337), Expect = 3e-31
 Identities = 81/217 (37%), Positives = 111/217 (51%), Gaps = 8/217 (3%)
 Frame = -1

Query: 730 PFNDMGRII--EAKPLVYECGPSCKCPPTCHNRVGQKGIKFRLQVFKTKSMGWGVKTLDY 557
           P++   RII  E  P VYEC   C C  TC NRV Q GI+ +L+VF+T+S GWG++  ++
Sbjct: 6   PYDGKQRIILEEGYP-VYECNKFCGCSRTCQNRVLQNGIRAKLEVFRTESKGWGLRACEH 64

Query: 556 IPSGSFVCEYIGEVLDDEEAQKRMTD------EYLFAIGHNYYDETLWEGLSRSIPSLQN 395
           I  G+FVCEYIGEVLD +EA KR          Y+  I  N  D                
Sbjct: 65  ILRGTFVCEYIGEVLDQQEANKRRNQYGNGDCSYILDIDANIND---------------I 109

Query: 394 GPGNDEEAGFAVDASKMGNFAKFINHSCTPNLYAQNALYDHDDKSAPHIMFFACENIPPG 215
           G   +EE  +A+DA+  GN ++FINHSC+PNL     + +  +    HI  +A  +I  G
Sbjct: 110 GRLMEEELDYAIDATTHGNISRFINHSCSPNLVNHQVIVESMESPLAHIGLYASMDIAAG 169

Query: 214 QELVYHYNYAIDQVYDENGNIKKKKCLCGSTECDGWL 104
           +E+   Y         EN    +  C C +T C G L
Sbjct: 170 EEITRDYGRRPVPSEQEN----EHPCHCKATNCRGLL 202



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>SUV91_MOUSE (O54864) Histone-lysine N-methyltransferase, H3 lysine-9 specific 1|
           (EC 2.1.1.43) (Histone H3-K9 methyltransferase 1)
           (H3-K9-HMTase 1) (Suppressor of variegation 3-9 homolog
           1) (Su(var)3-9 homolog 1) (Position-effect variegation
           3-9 homolog)
          Length = 412

 Score =  132 bits (332), Expect = 1e-30
 Identities = 81/233 (34%), Positives = 118/233 (50%), Gaps = 24/233 (10%)
 Frame = -1

Query: 727 FNDMGRI-IEAKPLVYECGPSCKCPPTCHNRVGQKGIKFRLQVFKTKS-MGWGVKTLDYI 554
           +ND G++ ++A   +YEC   C C   C NRV QKGI++ L +F+T    GWGV+TL+ I
Sbjct: 205 YNDQGQVRLKAGQPIYECNSRCCCGYDCPNRVVQKGIRYDLCIFRTNDGRGWGVRTLEKI 264

Query: 553 PSGSFVCEYIGEVLDDEEAQKR------MTDEYLFAIGHNYYDETLWEGLSRSIPSLQNG 392
              SFV EY+GE++  EEA++R          YLF +  +Y ++                
Sbjct: 265 RKNSFVMEYVGEIITSEEAERRGQIYDRQGATYLFDL--DYVEDV--------------- 307

Query: 391 PGNDEEAGFAVDASKMGNFAKFINHSCTPNLYAQNALYDHDDKSAPHIMFFACENIPPGQ 212
                   + VDA+  GN + F+NHSC PNL   N   D+ D+  P I FFA   I  G+
Sbjct: 308 --------YTVDAAYYGNISHFVNHSCDPNLQVYNVFIDNLDERLPRIAFFATRTIWAGE 359

Query: 211 ELVYHYNYAIDQVYDEN-------------GNIKKK---KCLCGSTECDGWLY 101
           EL + YN  +D V  E+             G+ KK+   +C CG+T C  +L+
Sbjct: 360 ELTFDYNMQVDPVDMESTRMDSNFGLAGLPGSPKKRVRIECKCGTTACRKYLF 412



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>SUVH2_ARATH (O22781) Histone-lysine N-methyltransferase, H3 lysine-9, H3|
            lysine-27, H4 lysine-20 and cytosine specific SUVH2 (EC
            2.1.1.43) (Histone H3-K9 methyltransferase 2)
            (H3-K9-HMTase 2) (H3-K27-HMTase 2) (H4-K20-HMTase 2)
            (Cytosine-HMTase 2) (Suppr
          Length = 651

 Score =  132 bits (331), Expect = 1e-30
 Identities = 71/184 (38%), Positives = 107/184 (58%), Gaps = 3/184 (1%)
 Frame = -1

Query: 727  FNDMGRIIEAKPLVYECGPSCKCPPTCHNRVGQKGIKFRLQVFKTKSMGWGVKTLDYIPS 548
            ++D G +++ K +V+ECG  C C P+C +RV QKG++ RL+VF++K  GWGV+TLD I +
Sbjct: 458  YDDNGHLLKGKHVVFECGEFCTCGPSCKSRVTQKGLRNRLEVFRSKETGWGVRTLDLIEA 517

Query: 547  GSFVCEYIGEVLDDEEAQKRMTDEYLFAIGHNYYDE-TLWEGLSRSIPSL--QNGPGNDE 377
            G+F+CEY G V+   +A+    +  +      + D+   W  LS+  P     N P +  
Sbjct: 518  GAFICEYAGVVVTRLQAEILSMNGDVMVYPGRFTDQWRNWGDLSQVYPDFVRPNYP-SLP 576

Query: 376  EAGFAVDASKMGNFAKFINHSCTPNLYAQNALYDHDDKSAPHIMFFACENIPPGQELVYH 197
               F++D S+M N A +I+HS  PN+  Q  L+DH+    P +M FA ENI P  EL   
Sbjct: 577  PLDFSMDVSRMRNVACYISHSKEPNVMVQFVLHDHNHLMFPRVMLFALENISPLAELSLD 636

Query: 196  YNYA 185
            Y  A
Sbjct: 637  YGLA 640



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>SUV91_HUMAN (O43463) Histone-lysine N-methyltransferase, H3 lysine-9 specific 1|
           (EC 2.1.1.43) (Histone H3-K9 methyltransferase 1)
           (H3-K9-HMTase 1) (Suppressor of variegation 3-9 homolog
           1) (Su(var)3-9 homolog 1)
          Length = 412

 Score =  131 bits (330), Expect = 2e-30
 Identities = 80/233 (34%), Positives = 117/233 (50%), Gaps = 24/233 (10%)
 Frame = -1

Query: 727 FNDMGRI-IEAKPLVYECGPSCKCPPTCHNRVGQKGIKFRLQVFKTKS-MGWGVKTLDYI 554
           +ND G++ + A   +YEC   C+C   C NRV QKGI++ L +F+T    GWGV+TL+ I
Sbjct: 205 YNDQGQVRLRAGLPIYECNSRCRCGYDCPNRVVQKGIRYDLCIFRTDDGRGWGVRTLEKI 264

Query: 553 PSGSFVCEYIGEVLDDEEAQKR------MTDEYLFAIGHNYYDETLWEGLSRSIPSLQNG 392
              SFV EY+GE++  EEA++R          YLF +  +Y ++                
Sbjct: 265 RKNSFVMEYVGEIITSEEAERRGQIYDRQGATYLFDL--DYVEDV--------------- 307

Query: 391 PGNDEEAGFAVDASKMGNFAKFINHSCTPNLYAQNALYDHDDKSAPHIMFFACENIPPGQ 212
                   + VDA+  GN + F+NHSC PNL   N   D+ D+  P I FFA   I  G+
Sbjct: 308 --------YTVDAAYYGNISHFVNHSCDPNLQVYNVFIDNLDERLPRIAFFATRTIRAGE 359

Query: 211 ELVYHYNYAIDQVYDEN-------------GNIKKK---KCLCGSTECDGWLY 101
           EL + YN  +D V  E+             G+ KK+   +C CG+  C  +L+
Sbjct: 360 ELTFDYNMQVDPVDMESTRMDSNFGLAGLPGSPKKRVRIECKCGTESCRKYLF 412



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>CLR4_SCHPO (O60016) Histone-lysine N-methyltransferase, H3 lysine-9 specific|
           (EC 2.1.1.43) (Histone H3-K9 methyltransferase)
           (H3-K9-HMTase) (Cryptic loci regulator 4)
          Length = 490

 Score =  130 bits (326), Expect = 5e-30
 Identities = 74/217 (34%), Positives = 116/217 (53%), Gaps = 8/217 (3%)
 Frame = -1

Query: 727 FNDMGRI-IEAKPLVYECGPSCKCPPTCHNRVGQKGIKFRLQVFKTKSMGWGVKTLDYIP 551
           ++  GR+  +   ++YEC   C C   C NRV Q+G    L++FKTK  GWGV++L + P
Sbjct: 290 YDAQGRVRADTGAVIYECNSFCSCSMECPNRVVQRGRTLPLEIFKTKEKGWGVRSLRFAP 349

Query: 550 SGSFVCEYIGEVLDDEEAQKRMTDEYLFAIGHNYYDETLWEGLSRSIPSLQNGPGNDEEA 371
           +G+F+  Y+GEV+   EA KR           NY D+         I  L +    D+ +
Sbjct: 350 AGTFITCYLGEVITSAEAAKR---------DKNYDDD--------GITYLFDLDMFDDAS 392

Query: 370 GFAVDASKMGNFAKFINHSCTPNLYAQNALYDHDDKSAPHIMFFACENIPPGQELVYHYN 191
            + VDA   G+ ++F NHSC+PN+   +A+ +H  ++   + FFA ++I P +EL + Y 
Sbjct: 393 EYTVDAQNYGDVSRFFNHSCSPNIAIYSAVRNHGFRTIYDLAFFAIKDIQPLEELTFDYA 452

Query: 190 YAID------QVYDENGNIK-KKKCLCGSTECDGWLY 101
            A D      Q   +N   K +++C CGS  C GWL+
Sbjct: 453 GAKDFSPVQSQKSQQNRISKLRRQCKCGSANCRGWLF 489



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>DIM5_NEUCR (Q8X225) Histone-lysine N-methyltransferase, H3 lysine-9 specific|
           dim-5 (EC 2.1.1.43) (Histone H3-K9 methyltransferase
           dim-5) (H3-K9-HMTase dim-5) (HKMT)
          Length = 318

 Score =  122 bits (307), Expect = 9e-28
 Identities = 73/216 (33%), Positives = 105/216 (48%), Gaps = 12/216 (5%)
 Frame = -1

Query: 712 RIIEAKPLVYECGPSCKCPPTCHNRVGQKGIKFRLQVFKTKSMGWGVKTLDYIPSGSFVC 533
           R+++++  +YEC   C C   C NRV ++G    LQ+F+TK  GWGVK    I  G FV 
Sbjct: 117 RVLQSQEPIYECHQGCACSKDCPNRVVERGRTVPLQIFRTKDRGWGVKCPVNIKRGQFVD 176

Query: 532 EYIGEVLDDEEAQKRMT--------DEYLFAIGHNYYDETLWEGLSRSIPSLQNGPGNDE 377
            Y+GE++  EEA +R          D YLFA+      ++L        P L   P    
Sbjct: 177 RYLGEIITSEEADRRRAESTIARRKDVYLFALDKFSDPDSL-------DPLLAGQP---- 225

Query: 376 EAGFAVDASKMGNFAKFINHSCTPNLYAQNALYDHDDKSAPHIMFFACENIPPGQELVYH 197
                VD   M    +FINHSC PN+     + DH DK    +  FA ++IP G EL + 
Sbjct: 226 ---LEVDGEYMSGPTRFINHSCDPNMAIFARVGDHADKHIHDLALFAIKDIPKGTELTFD 282

Query: 196 YNYAI----DQVYDENGNIKKKKCLCGSTECDGWLY 101
           Y   +       +D +   +  KCLCG+ +C G+L+
Sbjct: 283 YVNGLTGLESDAHDPSKISEMTKCLCGTAKCRGYLW 318



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>SUV92_HUMAN (Q9H5I1) Histone-lysine N-methyltransferase, H3 lysine-9 specific 2|
           (EC 2.1.1.43) (Histone H3-K9 methyltransferase 2)
           (H3-K9-HMTase 2) (Suppressor of variegation 3-9 homolog
           2) (Su(var)3-9 homolog 2)
          Length = 410

 Score =  122 bits (306), Expect = 1e-27
 Identities = 74/203 (36%), Positives = 104/203 (51%), Gaps = 8/203 (3%)
 Frame = -1

Query: 688 VYECGPSCKCPPTCHNRVGQKGIKFRLQVFKTKS-MGWGVKTLDYIPSGSFVCEYIGEVL 512
           +YEC   C+C P C NR+ QKG ++ L +F+T +  GWGVKTL  I   SFV EY+GEV+
Sbjct: 226 IYECNSRCQCGPDCPNRIVQKGTQYSLCIFRTSNGRGWGVKTLVKIKRMSFVMEYVGEVI 285

Query: 511 DDEEAQKRMTDEYLFAIGHNYYDETLWEGLSRSIPSLQNGPGNDEEAGFAVDASKMGNFA 332
             EEA++R            +YD       ++ I  L +     +E  F VDA++ GN +
Sbjct: 286 TSEEAERR----------GQFYD-------NKGITYLFDLDYESDE--FTVDAARYGNVS 326

Query: 331 KFINHSCTPNLYAQNALYDHDDKSAPHIMFFACENIPPGQELVYHYNYA----IDQVYDE 164
            F+NHSC PNL   N   D+ D   P I  F+   I  G+EL + Y       I     +
Sbjct: 327 HFVNHSCDPNLQVFNVFIDNLDTRLPRIALFSTRTINAGEELTFDYQMKGSGDISSDSID 386

Query: 163 NGNIKKK---KCLCGSTECDGWL 104
           +   KK+    C CG+  C G+L
Sbjct: 387 HSPAKKRVRTVCKCGAVTCRGYL 409



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>SUV92_MOUSE (Q9EQQ0) Histone-lysine N-methyltransferase, H3 lysine-9 specific 2|
           (EC 2.1.1.43) (Histone H3-K9 methyltransferase 2)
           (H3-K9-HMTase 2) (Suppressor of variegation 3-9 homolog
           2) (Su(var)3-9 homolog 2)
          Length = 477

 Score =  122 bits (305), Expect = 1e-27
 Identities = 74/203 (36%), Positives = 104/203 (51%), Gaps = 8/203 (3%)
 Frame = -1

Query: 688 VYECGPSCKCPPTCHNRVGQKGIKFRLQVFKTKS-MGWGVKTLDYIPSGSFVCEYIGEVL 512
           +YEC   C+C P C NR+ QKG ++ L +FKT +  GWGVKTL  I   SFV EY+GEV+
Sbjct: 293 IYECNSRCRCGPECPNRIVQKGTQYSLCIFKTSNGCGWGVKTLVKIKRMSFVMEYVGEVI 352

Query: 511 DDEEAQKRMTDEYLFAIGHNYYDETLWEGLSRSIPSLQNGPGNDEEAGFAVDASKMGNFA 332
             EEA++R            +YD       ++ I  L +     +E  F VDA++ GN +
Sbjct: 353 TSEEAERR----------GQFYD-------NKGITYLFDLDYESDE--FTVDAARYGNVS 393

Query: 331 KFINHSCTPNLYAQNALYDHDDKSAPHIMFFACENIPPGQELVYHYNY-----AIDQVYD 167
            F+NHSC PNL   +   D+ D   P I  F+   I  G+EL + Y       A     D
Sbjct: 394 HFVNHSCDPNLQVFSVFIDNLDTRLPRIALFSTRTINAGEELTFDYQMKGSGEASSDSID 453

Query: 166 ENGNIK--KKKCLCGSTECDGWL 104
            +   K  + +C CG+  C G+L
Sbjct: 454 HSPAKKRVRTQCKCGAETCRGYL 476



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>SUVH8_ARATH (Q9C5P0) Histone-lysine N-methyltransferase, H3 lysine-9 specific|
            SUVH8 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 8)
            (H3-K9-HMTase 8) (Suppressor of variegation 3-9 homolog
            protein 8) (Su(var)3-9 homolog protein 8) (Protein SET
            DOMAIN GR
          Length = 755

 Score =  119 bits (297), Expect = 1e-26
 Identities = 77/217 (35%), Positives = 114/217 (52%), Gaps = 10/217 (4%)
 Frame = -1

Query: 730  PFNDMGRIIEAKPLVYECGPSCKCPPTCHNRVGQKGIKFRLQVFKTKSMGWGVKTLDYIP 551
            P++D   ++  KPL+YECG SC   PT   R+ + G+K  L+VFKT + GWG+++ D I 
Sbjct: 550  PYHD-NILVCRKPLIYECGGSC---PT---RMVETGLKLHLEVFKTSNCGWGLRSWDPIR 602

Query: 550  SGSFVCEYIGEVLDDEEAQKRMTDEYLF-------AIGHNYYDETLWEGLSRSIPSLQNG 392
            +G+F+CE+ G     EE ++   D+YLF       +   NY  E L E     +    N 
Sbjct: 603  AGTFICEFTGVSKTKEEVEE--DDDYLFDTSRIYHSFRWNYEPELLCEDACEQVSEDANL 660

Query: 391  PGNDEEAGFAVDASKMGNFAKFINHSCTPNLYAQNALYDHDDKSA-PHIMFFACENIPPG 215
            P         + A + GN  +F+NH+C PN++ Q   YD ++      I  FA ++IPP 
Sbjct: 661  P-----TQVLISAKEKGNVGRFMNHNCWPNVFWQPIEYDDNNGHIYVRIGLFAMKHIPPM 715

Query: 214  QELVYHYNYAIDQVYDENGNIKKKK--CLCGSTECDG 110
             EL Y Y  +  +   E+  I K K  CLCGS +C G
Sbjct: 716  TELTYDYGISCVEKTGEDEVIYKGKKICLCGSVKCRG 752



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>SUV9_DROME (P45975) Histone-lysine N-methyltransferase, H3 lysine-9 specific|
           (EC 2.1.1.43) (Histone H3-K9 methyltransferase)
           (H3-K9-HMTase) (Protein suppressor of variegation 3-9)
          Length = 635

 Score =  112 bits (281), Expect = 9e-25
 Identities = 65/200 (32%), Positives = 97/200 (48%), Gaps = 9/200 (4%)
 Frame = -1

Query: 688 VYECGPSCKCPPTCHNRVGQKGIKFRLQVFKTKS-MGWGVKTLDYIPSGSFVCEYIGEVL 512
           +YEC   C C  +C NR+ Q G +  L +FKT +  GWGV+    +  G FVCEYIGE++
Sbjct: 453 IYECNSRCSCDSSCSNRLVQHGRQVPLVLFKTANGSGWGVRAATALRKGEFVCEYIGEII 512

Query: 511 DDEEAQKR--MTDE----YLFAIGHNYYDETLWEGLSRSIPSLQNGPGNDEEAGFAVDAS 350
             +EA +R    D+    YLF + +N                        +++ + +DA+
Sbjct: 513 TSDEANERGKAYDDNGRTYLFDLDYN----------------------TAQDSEYTIDAA 550

Query: 349 KMGNFAKFINHSCTPNLYAQNALYDHDDKSAPHIMFFACENIPPGQELVYHYNYA--IDQ 176
             GN + FINHSC PNL       +H + + PH++FF    I  G+EL + Y  A   D 
Sbjct: 551 NYGNISHFINHSCDPNLAVFPCWIEHLNVALPHLVFFTLRPIKAGEELSFDYIRADNEDV 610

Query: 175 VYDENGNIKKKKCLCGSTEC 116
            Y+      + +C CG   C
Sbjct: 611 PYENLSTAVRVECRCGRDNC 630



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>SUVR4_ARATH (Q8W595) Histone-lysine N-methyltransferase SUVR4 (EC 2.1.1.43)|
           (Suppressor of variegation 3-9-related protein 4)
           (Su(var)3-9-related protein 4) (Protein SET DOMAIN GROUP
           31)
          Length = 492

 Score =  101 bits (251), Expect = 3e-21
 Identities = 69/199 (34%), Positives = 101/199 (50%), Gaps = 5/199 (2%)
 Frame = -1

Query: 697 KPLVYECGPSCKCPPTCHNRVGQKGIKFRLQVFKTKS-MGWGVKTLDYIPSGSFVCEYIG 521
           +  + EC   C C   C NRV Q+GI+ +LQV+ T+   GWG++TL  +P G+F+CEYIG
Sbjct: 275 RKFIKECWRKCGCDMQCGNRVVQRGIRCQLQVYFTQEGKGWGLRTLQDLPKGTFICEYIG 334

Query: 520 EVLDDEEAQKRMTDEYLFAIGHNYYDETL---WEGLSRSIPSLQNGPGNDEEAGFAVDAS 350
           E+L + E   R       +   + Y  TL   W G  + +         DEEA   +DA+
Sbjct: 335 EILTNTELYDRNVRS---SSERHTYPVTLDADW-GSEKDL--------KDEEA-LCLDAT 381

Query: 349 KMGNFAKFINHSC-TPNLYAQNALYDHDDKSAPHIMFFACENIPPGQELVYHYNYAIDQV 173
             GN A+FINH C   N+       +  D+   HI FF   ++    EL   ++Y ID  
Sbjct: 382 ICGNVARFINHRCEDANMIDIPIEIETPDRHYYHIAFFTLRDVKAMDELT--WDYMID-F 438

Query: 172 YDENGNIKKKKCLCGSTEC 116
            D++  +K  +C CGS  C
Sbjct: 439 NDKSHPVKAFRCCCGSESC 457



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>SUVR1_ARATH (Q946J2) Histone-lysine N-methyltransferase SUVR1 (EC 2.1.1.43)|
           (Suppressor of variegation 3-9-related protein 1)
           (Su(var)3-9-related protein 1) (Protein SET DOMAIN GROUP
           13)
          Length = 630

 Score = 95.1 bits (235), Expect = 2e-19
 Identities = 62/199 (31%), Positives = 97/199 (48%), Gaps = 8/199 (4%)
 Frame = -1

Query: 688 VYECGPSCKCPPTCHNRVGQKGIKFRLQVFKTKS-MGWGVKTLDYIPSGSFVCEYIGEVL 512
           + EC   C C   C NRV Q+G+  +LQVF T +  GWG++TL+ +P G+F+CEYIGE+L
Sbjct: 438 IKECWFKCGCTKRCGNRVVQRGMHNKLQVFFTPNGKGWGLRTLEKLPKGAFICEYIGEIL 497

Query: 511 DDEEAQKRMTDEYLFAIGHNYYDETLWEGLSRSIPSLQNGPGNDEE-----AGFAVDASK 347
              E  +R  ++                    ++P + +     EE         +D   
Sbjct: 498 TIPELYQRSFED------------------KPTLPVILDAHWGSEERLEGDKALCLDGMF 539

Query: 346 MGNFAKFINHSC-TPNLYAQNALYDHDDKSAPHIMFFACENIPPGQELVYHYNYAIDQVY 170
            GN ++F+NH C   NL       +  D+   H+ FF   +I   +EL   ++Y ID  +
Sbjct: 540 YGNISRFLNHRCLDANLIEIPVQVETPDQHYYHLAFFTTRDIEAMEELA--WDYGID--F 595

Query: 169 DENGNIKKK-KCLCGSTEC 116
           ++N ++ K   CLCGS  C
Sbjct: 596 NDNDSLMKPFDCLCGSRFC 614



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>NSD1_HUMAN (Q96L73) Histone-lysine N-methyltransferase, H3 lysine-36 and H4|
            lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase)
            (H4-K20-HMTase) (Nuclear receptor binding SET domain
            containing protein 1) (NR-binding SET domain containing
            protein) (Androgen r
          Length = 2696

 Score = 91.7 bits (226), Expect = 2e-18
 Identities = 63/200 (31%), Positives = 94/200 (47%), Gaps = 4/200 (2%)
 Frame = -1

Query: 691  LVYECGPS-CKCPPTCHNRVGQKGIKFRLQVFKTKSMGWGVKTLDYIPSGSFVCEYIGEV 515
            L+YEC P+ C     C N+   K     +++F+T   GWG++T   I  G FV EY+GE+
Sbjct: 1916 LLYECHPTVCPAGGRCQNQCFSKRQYPEVEIFRTLQRGWGLRTKTDIKKGEFVNEYVGEL 1975

Query: 514  LDDEEAQKRMTDEYLFAIGH---NYYDETLWEGLSRSIPSLQNGPGNDEEAGFAVDASKM 344
            +D+EE + R+     +A  H   N+Y  TL                   +    +DA   
Sbjct: 1976 IDEEECRARIR----YAQEHDITNFYMLTL-------------------DKDRIIDAGPK 2012

Query: 343  GNFAKFINHSCTPNLYAQNALYDHDDKSAPHIMFFACENIPPGQELVYHYNYAIDQVYDE 164
            GN+A+F+NH C PN   Q    + D +    +  FA  +I  G EL ++YN       + 
Sbjct: 2013 GNYARFMNHCCQPNCETQKWSVNGDTR----VGLFALSDIKAGTELTFNYN------LEC 2062

Query: 163  NGNIKKKKCLCGSTECDGWL 104
             GN  K  C CG+  C G+L
Sbjct: 2063 LGN-GKTVCKCGAPNCSGFL 2081



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>ASHH1_ARATH (Q84WW6) Histone-lysine N-methyltransferase ASHH1 (EC 2.1.1.43)|
           (ASH1-homolog protein 1) (Protein SET DOMAIN GROUP 26)
          Length = 492

 Score = 91.7 bits (226), Expect = 2e-18
 Identities = 66/196 (33%), Positives = 90/196 (45%), Gaps = 3/196 (1%)
 Frame = -1

Query: 682 ECGPS-CKCPPTCHNRVGQKGIKFRLQVFKTKSMGWGVKTLDYIPSGSFVCEYIGEVLDD 506
           EC P  C C   C N+  QK    + ++ K +  GWG+  L+ I +G F+ EY GEV+  
Sbjct: 66  ECTPGYCPCGVYCKNQKFQKCEYAKTKLIKCEGRGWGLVALEEIKAGQFIMEYCGEVISW 125

Query: 505 EEAQKRMTDEYLFAIGHNYYDETLWEGLSRSIPSLQNGPGNDEEAGFAVDASKMGNFAKF 326
           +EA+KR        +   Y            I SL         A  A+DA+K G+ A+F
Sbjct: 126 KEAKKRAQTYETHGVKDAY------------IISL--------NASEAIDATKKGSLARF 165

Query: 325 INHSCTPNLYAQ--NALYDHDDKSAPHIMFFACENIPPGQELVYHYNYAIDQVYDENGNI 152
           INHSC PN   +  N L          +  FA E+I P  EL Y YN+       E    
Sbjct: 166 INHSCRPNCETRKWNVL------GEVRVGIFAKESISPRTELAYDYNF-------EWYGG 212

Query: 151 KKKKCLCGSTECDGWL 104
            K +CLCG+  C G+L
Sbjct: 213 AKVRCLCGAVACSGFL 228



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>NSD1_MOUSE (O88491) Histone-lysine N-methyltransferase, H3 lysine-36 and H4|
            lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase)
            (H4-K20-HMTase) (Nuclear receptor binding SET domain
            containing protein 1) (NR-binding SET domain containing
            protein)
          Length = 2588

 Score = 90.9 bits (224), Expect = 4e-18
 Identities = 63/200 (31%), Positives = 94/200 (47%), Gaps = 4/200 (2%)
 Frame = -1

Query: 691  LVYECGPS-CKCPPTCHNRVGQKGIKFRLQVFKTKSMGWGVKTLDYIPSGSFVCEYIGEV 515
            L+YEC P+ C     C N+   K     +++F+T   GWG++T   I  G FV EY+GE+
Sbjct: 1814 LLYECHPTVCPAGVRCQNQCFSKRQYPDVEIFRTLQRGWGLRTKTDIKKGEFVNEYVGEL 1873

Query: 514  LDDEEAQKRMTDEYLFAIGH---NYYDETLWEGLSRSIPSLQNGPGNDEEAGFAVDASKM 344
            +D+EE + R+     +A  H   N+Y  TL                   +    +DA   
Sbjct: 1874 IDEEECRARIR----YAQEHDITNFYMLTL-------------------DKDRIIDAGPK 1910

Query: 343  GNFAKFINHSCTPNLYAQNALYDHDDKSAPHIMFFACENIPPGQELVYHYNYAIDQVYDE 164
            GN+A+F+NH C PN   Q    + D +    +  FA  +I  G EL ++YN       + 
Sbjct: 1911 GNYARFMNHCCQPNCETQKWSVNGDTR----VGLFALSDIKAGTELTFNYN------LEC 1960

Query: 163  NGNIKKKKCLCGSTECDGWL 104
             GN  K  C CG+  C G+L
Sbjct: 1961 LGN-GKTVCKCGAPNCSGFL 1979



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>SETB1_MOUSE (O88974) Histone-lysine N-methyltransferase, H3 lysine-9 specific 4|
            (EC 2.1.1.43) (Histone H3-K9 methyltransferase 4)
            (H3-K9-HMTase 4) (SET domain bifurcated 1)
            (ERG-associated protein with SET domain) (ESET)
          Length = 1307

 Score = 90.5 bits (223), Expect = 5e-18
 Identities = 49/116 (42%), Positives = 65/116 (56%), Gaps = 5/116 (4%)
 Frame = -1

Query: 712  RIIEAKPL-VYECGPSCKCPPT-CHNRVGQKGIKFRLQVFKTKSMGWGVKTLDYIPSGSF 539
            R+ E  P  VYEC   C C P  C NR+ Q G++ RLQ+FKT++ GWG++ LD I  GSF
Sbjct: 786  RLEECLPTGVYECNKRCNCDPNMCTNRLVQHGLQVRLQLFKTQNKGWGIRCLDDIAKGSF 845

Query: 538  VCEYIGEVLDDEEAQK---RMTDEYLFAIGHNYYDETLWEGLSRSIPSLQNGPGND 380
            VC Y G++L D+ A K    M DEY   + H    E   EG    +P+  +  G D
Sbjct: 846  VCIYAGKILTDDFADKEGLEMGDEYFANLDHIESVENFKEGYESDVPTSSDSSGVD 901



 Score = 77.4 bits (189), Expect = 4e-14
 Identities = 37/92 (40%), Positives = 51/92 (55%)
 Frame = -1

Query: 379  EEAGFAVDASKMGNFAKFINHSCTPNLYAQNALYDHDDKSAPHIMFFACENIPPGQELVY 200
            EE+ + +DA   GN  +++NHSC+PNL+ QN   D  D   P + FFA + I  G EL +
Sbjct: 1220 EESCYIIDAKLEGNLGRYLNHSCSPNLFVQNVFVDTHDLRFPWVAFFASKRIRAGTELTW 1279

Query: 199  HYNYAIDQVYDENGNIKKKKCLCGSTECDGWL 104
             YNY +  V       K+  C CG+ EC G L
Sbjct: 1280 DYNYEVGSVEG-----KELLCCCGAIECRGRL 1306



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>MES4_DROME (Q8MT36) Probable histone methyltransferase Mes-4 (Maternal-effect|
            sterile 4)
          Length = 1427

 Score = 90.5 bits (223), Expect = 5e-18
 Identities = 62/195 (31%), Positives = 89/195 (45%), Gaps = 1/195 (0%)
 Frame = -1

Query: 691  LVYECGPS-CKCPPTCHNRVGQKGIKFRLQVFKTKSMGWGVKTLDYIPSGSFVCEYIGEV 515
            L  EC P  CK    C NR+ ++    RL+V      G+G+   + I  G FV EY+GEV
Sbjct: 1208 LFNECNPEYCKAGSLCENRMFEQRKSPRLEVVYMNERGFGLVNREPIAVGDFVIEYVGEV 1267

Query: 514  LDDEEAQKRMTDEYLFAIGHNYYDETLWEGLSRSIPSLQNGPGNDEEAGFAVDASKMGNF 335
            ++  E Q+RM  +       NYY    + G+               E  F +DA   GN 
Sbjct: 1268 INHAEFQRRMEQKQRDR-DENYY----FLGV---------------EKDFIIDAGPKGNL 1307

Query: 334  AKFINHSCTPNLYAQNALYDHDDKSAPHIMFFACENIPPGQELVYHYNYAIDQVYDENGN 155
            A+F+NHSC PN   Q    +        +  FA ++IP   EL ++Y      ++D+  N
Sbjct: 1308 ARFMNHSCEPNCETQKWTVN----CIHRVGIFAIKDIPVNSELTFNY------LWDDLMN 1357

Query: 154  IKKKKCLCGSTECDG 110
              KK C CG+  C G
Sbjct: 1358 NSKKACFCGAKRCSG 1372



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>ASHR3_ARATH (Q949T8) Histone-lysine N-methyltransferase ASHR3 precursor (EC|
           2.1.1.43) (ASH1-related protein 3) (Protein SET DOMAIN
           GROUP 4) (Protein stamen loss)
          Length = 497

 Score = 90.1 bits (222), Expect = 6e-18
 Identities = 56/192 (29%), Positives = 87/192 (45%)
 Frame = -1

Query: 679 CGPSCKCPPTCHNRVGQKGIKFRLQVFKTKSMGWGVKTLDYIPSGSFVCEYIGEVLDDEE 500
           C   C CP +C NR  +K  K  +++ KT+  GWGV+  + I    F+ EYIGEV+ D +
Sbjct: 307 CSKGCSCPESCGNRPFRKEKK--IKIVKTEHCGWGVEAAESINKEDFIVEYIGEVISDAQ 364

Query: 499 AQKRMTDEYLFAIGHNYYDETLWEGLSRSIPSLQNGPGNDEEAGFAVDASKMGNFAKFIN 320
            ++R+ D     +   Y  E                     +  F +DA+  GN ++F+N
Sbjct: 365 CEQRLWDMKHKGMKDFYMCEI--------------------QKDFTIDATFKGNASRFLN 404

Query: 319 HSCTPNLYAQNALYDHDDKSAPHIMFFACENIPPGQELVYHYNYAIDQVYDENGNIKKKK 140
           HSC PN   +    + + +    +  FA   I  G+ L Y Y +       + G   + K
Sbjct: 405 HSCNPNCVLEKWQVEGETR----VGVFAARQIEAGEPLTYDYRFV------QFG--PEVK 452

Query: 139 CLCGSTECDGWL 104
           C CGS  C G+L
Sbjct: 453 CNCGSENCQGYL 464



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>SETB1_HUMAN (Q15047) Histone-lysine N-methyltransferase, H3 lysine-9 specific 4|
            (EC 2.1.1.43) (Histone H3-K9 methyltransferase 4)
            (H3-K9-HMTase 4) (SET domain bifurcated 1)
            (ERG-associated protein with SET domain) (ESET)
          Length = 1291

 Score = 90.1 bits (222), Expect = 6e-18
 Identities = 50/116 (43%), Positives = 64/116 (55%), Gaps = 5/116 (4%)
 Frame = -1

Query: 712  RIIEAKPL-VYECGPSCKCPPT-CHNRVGQKGIKFRLQVFKTKSMGWGVKTLDYIPSGSF 539
            R+ E  P  VYEC   CKC P  C NR+ Q G++ RLQ+FKT++ GWG++ LD I  GSF
Sbjct: 769  RLEECLPTGVYECNKRCKCDPNMCTNRLVQHGLQVRLQLFKTQNKGWGIRCLDDIAKGSF 828

Query: 538  VCEYIGEVLDDEEAQK---RMTDEYLFAIGHNYYDETLWEGLSRSIPSLQNGPGND 380
            VC Y G++L D+ A K    M DEY   + H    E   EG     P   +  G D
Sbjct: 829  VCIYAGKILTDDFADKEGLEMGDEYFANLDHIESVENFKEGYESDAPCSSDSSGVD 884



 Score = 77.4 bits (189), Expect = 4e-14
 Identities = 37/92 (40%), Positives = 51/92 (55%)
 Frame = -1

Query: 379  EEAGFAVDASKMGNFAKFINHSCTPNLYAQNALYDHDDKSAPHIMFFACENIPPGQELVY 200
            EE+ + +DA   GN  +++NHSC+PNL+ QN   D  D   P + FFA + I  G EL +
Sbjct: 1204 EESCYIIDAKLEGNLGRYLNHSCSPNLFVQNVFVDTHDLRFPWVAFFASKRIRAGTELTW 1263

Query: 199  HYNYAIDQVYDENGNIKKKKCLCGSTECDGWL 104
             YNY +  V       K+  C CG+ EC G L
Sbjct: 1264 DYNYEVGSVEG-----KELLCCCGAIECRGRL 1290



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>SUVR2_ARATH (Q9FNC7) Histone-lysine N-methyltransferase SUVR2 (EC 2.1.1.43)|
            (Suppressor of variegation 3-9-related protein 2)
            (Su(var)3-9-related protein 2) (Protein SET DOMAIN GROUP
            18)
          Length = 717

 Score = 88.2 bits (217), Expect = 2e-17
 Identities = 60/193 (31%), Positives = 90/193 (46%), Gaps = 2/193 (1%)
 Frame = -1

Query: 688  VYECGPSCKCPPTCHNRVGQKGIKFRLQVFKTKS-MGWGVKTLDYIPSGSFVCEYIGEVL 512
            + EC   C C   C NRV Q+GI  +LQVF T +  GWG++TL+ +P G+FVCE  GE+L
Sbjct: 526  IKECWSKCGCMKNCGNRVVQQGIHNKLQVFFTPNGRGWGLRTLEKLPKGAFVCELAGEIL 585

Query: 511  DDEEAQKRMTDEYLFAIGHNYYDETLWEGLSRSIPSLQNGPGNDEEAGFAVDASKMGNFA 332
               E  +R++D     +  + Y    W          ++  G+D+    +++ +  GN +
Sbjct: 586  TIPELFQRISDRPTSPVILDAY----W--------GSEDISGDDK--ALSLEGTHYGNIS 631

Query: 331  KFINHSC-TPNLYAQNALYDHDDKSAPHIMFFACENIPPGQELVYHYNYAIDQVYDENGN 155
            +FINH C   NL       +  D    H+ FF    I   +EL + Y    +Q       
Sbjct: 632  RFINHRCLDANLIEIPVHAETTDSHYYHLAFFTTREIDAMEELTWDYGVPFNQDVFPTSP 691

Query: 154  IKKKKCLCGSTEC 116
                 C CGS  C
Sbjct: 692  F---HCQCGSDFC 701



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>ASHH2_ARATH (Q2LAE1) Histone-lysine N-methyltransferase, H3 lysine-4 and H3|
            lysine-36 specific ASHH2 (EC 2.1.1.43) (H3-K4-HMTase)
            (H3-K36-HMTase) (Histone H3-K36 methyltransferase 8)
            (ASH1-homolog protein 2) (Protein EARLY FLOWERING IN
            SHORT DAYS) (Prote
          Length = 1759

 Score = 87.0 bits (214), Expect = 5e-17
 Identities = 56/189 (29%), Positives = 91/189 (48%)
 Frame = -1

Query: 670  SCKCPPTCHNRVGQKGIKFRLQVFKTKSMGWGVKTLDYIPSGSFVCEYIGEVLDDEEAQK 491
            +C     C N+  QK    + + F++   G+G++ L+ +  G F+ EY+GEVLD +  + 
Sbjct: 1008 TCPAGDLCSNQQFQKRKYVKFERFQSGKKGYGLRLLEDVREGQFLIEYVGEVLDMQSYET 1067

Query: 490  RMTDEYLFAIGHNYYDETLWEGLSRSIPSLQNGPGNDEEAGFAVDASKMGNFAKFINHSC 311
            R   EY F    ++Y  TL               GN+      +DA   GN  +FINHSC
Sbjct: 1068 RQ-KEYAFKGQKHFYFMTL--------------NGNE-----VIDAGAKGNLGRFINHSC 1107

Query: 310  TPNLYAQNALYDHDDKSAPHIMFFACENIPPGQELVYHYNYAIDQVYDENGNIKKKKCLC 131
             PN   +  + + +      +  F+ +++  GQEL + YNY   +V+        KKC C
Sbjct: 1108 EPNCRTEKWMVNGE----ICVGIFSMQDLKKGQELTFDYNYV--RVF----GAAAKKCYC 1157

Query: 130  GSTECDGWL 104
            GS+ C G++
Sbjct: 1158 GSSHCRGYI 1166



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>ASHH4_ARATH (Q9M1X9) Putative histone-lysine N-methyltransferase ASHH4 (EC|
           2.1.1.43) (ASH1-homolog protein 4) (Protein SET DOMAIN
           GROUP 24)
          Length = 352

 Score = 81.3 bits (199), Expect = 3e-15
 Identities = 54/197 (27%), Positives = 91/197 (46%), Gaps = 5/197 (2%)
 Frame = -1

Query: 691 LVYECGPSCKCPPTCHNRVGQKGIKFRLQVFKTKSMGWGVKTLDYIPSGSFVCEYIGEVL 512
           L+  C  SCKC   C N+  Q+    ++++ +T+  G+G+   + I SG F+ EY+GEV+
Sbjct: 86  LLSSCSSSCKCSSECTNKPFQQRHIKKMKLVQTEKCGYGIVADEDINSGEFIIEYVGEVI 145

Query: 511 DDEEAQKRMTDEYLFAIGHN-----YYDETLWEGLSRSIPSLQNGPGNDEEAGFAVDASK 347
           DD     ++ +E L+ + H      Y  +  W                       +DA+ 
Sbjct: 146 DD-----KICEERLWKLNHKVETNFYLCQINWN--------------------MVIDATH 180

Query: 346 MGNFAKFINHSCTPNLYAQNALYDHDDKSAPHIMFFACENIPPGQELVYHYNYAIDQVYD 167
            GN +++INHSC+PN   Q  + D + +    I  FA   I  G++L Y Y + +    D
Sbjct: 181 KGNKSRYINHSCSPNTEMQKWIIDGETR----IGIFATRFINKGEQLTYDYQF-VQFGAD 235

Query: 166 ENGNIKKKKCLCGSTEC 116
           ++       C CG+  C
Sbjct: 236 QD-------CYCGAVCC 245



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>ASHH3_ARATH (Q945S8) Histone-lysine N-methyltransferase ASHH3 (EC 2.1.1.43)|
           (ASH1-homolog protein 3) (Protein SET DOMAIN GROUP 7)
          Length = 363

 Score = 80.5 bits (197), Expect = 5e-15
 Identities = 52/192 (27%), Positives = 89/192 (46%)
 Frame = -1

Query: 691 LVYECGPSCKCPPTCHNRVGQKGIKFRLQVFKTKSMGWGVKTLDYIPSGSFVCEYIGEVL 512
           L   C  SCKC   C+N+  Q+    ++++ +T+  G G+   + I +G F+ EY+GEV+
Sbjct: 91  LFSSCSSSCKCGSECNNKPFQQRHVKKMKLIQTEKCGSGIVAEEEIEAGEFIIEYVGEVI 150

Query: 511 DDEEAQKRMTDEYLFAIGHNYYDETLWEGLSRSIPSLQNGPGNDEEAGFAVDASKMGNFA 332
           DD+  ++R     L+ + H          ++R +                +DA+  GN +
Sbjct: 151 DDKTCEER-----LWKMKHRGETNFYLCEITRDM---------------VIDATHKGNKS 190

Query: 331 KFINHSCTPNLYAQNALYDHDDKSAPHIMFFACENIPPGQELVYHYNYAIDQVYDENGNI 152
           ++INHSC PN   Q  + D + +    I  FA   I  G+ L Y Y + +    D++   
Sbjct: 191 RYINHSCNPNTQMQKWIIDGETR----IGIFATRGIKKGEHLTYDYQF-VQFGADQD--- 242

Query: 151 KKKKCLCGSTEC 116
               C CG+  C
Sbjct: 243 ----CHCGAVGC 250



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>MES4_CAEEL (Q9NH52) Probable histone methyltransferase mes-4 (Maternal-effect|
            sterile protein 4)
          Length = 898

 Score = 80.1 bits (196), Expect = 6e-15
 Identities = 57/205 (27%), Positives = 85/205 (41%), Gaps = 13/205 (6%)
 Frame = -1

Query: 685  YECGPSCKCPPTCHNRVGQKGI-KFRLQVFKTKSMGWGVKTLDYIPSGSFVCEYIGEVLD 509
            YEC PSC     CHNR    GI   ++++  T   G+GV     I    ++CEY+GE++D
Sbjct: 513  YECPPSCSKKGVCHNRQVSMGIVSEKIKLAATLCKGYGVFAKGQIEKDEYICEYVGEIID 572

Query: 508  DEEAQKRMTDEYLFA-IGHNYYDETLWEGLSRSIPSLQNGPGNDEEAGFAVDASKMGNFA 332
              E ++R+    +      N+Y   L +GL+                   VDA++ GN +
Sbjct: 573  KAEKKRRLDSVSISRDFQANHYMMELHKGLT-------------------VDAARYGNIS 613

Query: 331  KFINHSCTPNLYA-----------QNALYDHDDKSAPHIMFFACENIPPGQELVYHYNYA 185
            ++INHSC PN  +           + +LYD            A   I  G E+ + YN  
Sbjct: 614  RYINHSCDPNAASFVTKVFVKKTKEGSLYD------TRSYIRAIRTIDDGDEITFSYNM- 666

Query: 184  IDQVYDENGNIKKKKCLCGSTECDG 110
                   N       C CG+  C G
Sbjct: 667  -------NNEENLPDCECGAENCMG 684



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>SET2_YEAST (P46995) SET domain protein 2|
          Length = 733

 Score = 76.6 bits (187), Expect = 7e-14
 Identities = 54/186 (29%), Positives = 81/186 (43%)
 Frame = -1

Query: 661 CPPTCHNRVGQKGIKFRLQVFKTKSMGWGVKTLDYIPSGSFVCEYIGEVLDDEEAQKRMT 482
           C   C N+  QK     + +FKTK  G+GV+    I +  F+ EY GEV+++ E + R+ 
Sbjct: 105 CGNDCQNQRFQKKQYAPIAIFKTKHKGYGVRAEQDIEANQFIYEYKGEVIEEMEFRDRLI 164

Query: 481 DEYLFAIGHNYYDETLWEGLSRSIPSLQNGPGNDEEAGFAVDASKMGNFAKFINHSCTPN 302
           D       H Y+              LQNG          +DA+  G+ A+F NHSC+PN
Sbjct: 165 DYDQRHFKHFYF------------MMLQNGE--------FIDATIKGSLARFCNHSCSPN 204

Query: 301 LYAQNALYDHDDKSAPHIMFFACENIPPGQELVYHYNYAIDQVYDENGNIKKKKCLCGST 122
            Y    +     K    +  FA   I  G+E+ + YN        +    + +KC C   
Sbjct: 205 AYVNKWVV----KDKLRMGIFAQRKILKGEEITFDYNV-------DRYGAQAQKCYCEEP 253

Query: 121 ECDGWL 104
            C G+L
Sbjct: 254 NCIGFL 259



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>SET2_CAEEL (Q18221) Protein set-2|
          Length = 1507

 Score = 74.7 bits (182), Expect = 3e-13
 Identities = 49/176 (27%), Positives = 80/176 (45%), Gaps = 3/176 (1%)
 Frame = -1

Query: 622  IKFRLQVFK---TKSMGWGVKTLDYIPSGSFVCEYIGEVLDDEEAQKRMTDEYLFAIGHN 452
            +KFR ++ K   ++  GWG+  ++ I     + EYIG+ +    A++R        IG +
Sbjct: 1363 LKFRKKMIKFARSRIHGWGLYAMESIAPDEMIVEYIGQTIRSLVAEEREKAYERRGIGSS 1422

Query: 451  YYDETLWEGLSRSIPSLQNGPGNDEEAGFAVDASKMGNFAKFINHSCTPNLYAQNALYDH 272
            Y                        +    +DA+K GNFA+FINHSC PN YA+    + 
Sbjct: 1423 YLFRI--------------------DLHHVIDATKRGNFARFINHSCQPNCYAKVLTIEG 1462

Query: 271  DDKSAPHIMFFACENIPPGQELVYHYNYAIDQVYDENGNIKKKKCLCGSTECDGWL 104
            + +    I+ ++   I  G+E+ Y Y + I+          K  CLCG+  C G+L
Sbjct: 1463 EKR----IVIYSRTIIKKGEEITYDYKFPIED--------DKIDCLCGAKTCRGYL 1506



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>SETB2_HUMAN (Q96T68) Probable histone-lysine N-methyltransferase, H3 lysine-9|
           specific (EC 2.1.1.43) (Histone H3-K9 methyltransferase)
           (H3-K9-HMTase) (SET domain bifurcated 2) (Chronic
           lymphocytic leukemia deletion region gene 8 protein)
          Length = 719

 Score = 70.1 bits (170), Expect = 7e-12
 Identities = 39/90 (43%), Positives = 48/90 (53%), Gaps = 1/90 (1%)
 Frame = -1

Query: 688 VYECGPSCKCP-PTCHNRVGQKGIKFRLQVFKTKSMGWGVKTLDYIPSGSFVCEYIGEVL 512
           +YEC   CKC    C NRV Q G + RLQVFKT+  GWGV+ LD I  G+FVC Y G +L
Sbjct: 342 IYECSLLCKCNRQLCQNRVVQHGPQVRLQVFKTEQKGWGVRCLDDIDRGTFVCIYSGRLL 401

Query: 511 DDEEAQKRMTDEYLFAIGHNYYDETLWEGL 422
                  R   E  + I  N  DE   + +
Sbjct: 402 ------SRANTEKSYGIDENGRDENTMKNI 425



 Score = 60.8 bits (146), Expect = 4e-09
 Identities = 30/86 (34%), Positives = 45/86 (52%), Gaps = 2/86 (2%)
 Frame = -1

Query: 367 FAVDASKMGNFAKFINHSCTPNLYAQNALYDHDDKSAPHIMFFACENIPPGQELVYHYNY 188
           F +DA+K GN  +F+NHSC PNL  QN   +  +++ P + FF    +    EL + Y Y
Sbjct: 636 FLLDATKEGNVGRFLNHSCCPNLLVQNVFVETHNRNFPLVAFFTNRYVKARTELTWDYGY 695

Query: 187 AIDQVYDENGNIKKKK--CLCGSTEC 116
                  E G + +K+  C CG  +C
Sbjct: 696 -------EAGTVPEKEIFCQCGVNKC 714



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>EZ_DROME (P42124) Polycomb protein E(z) (Protein enhancer of zeste)|
          Length = 760

 Score = 69.7 bits (169), Expect = 9e-12
 Identities = 45/157 (28%), Positives = 70/157 (44%), Gaps = 2/157 (1%)
 Frame = -1

Query: 652  TCHNRVGQKGIKFRLQVFKTKSMGWGVKTLDYIPSGSFVCEYIGEVLDDEEAQKR--MTD 479
            TC N   Q+G+   L +  +   GWG+   +      F+ EY GE++  +EA +R  + D
Sbjct: 614  TCKNVCVQRGLHKHLLMAPSDIAGWGIFLKEGAQKNEFISEYCGEIISQDEADRRGKVYD 673

Query: 478  EYLFAIGHNYYDETLWEGLSRSIPSLQNGPGNDEEAGFAVDASKMGNFAKFINHSCTPNL 299
            +Y+ +   N  ++                        F VDA++ GN  +F NHS  PN 
Sbjct: 674  KYMCSFLFNLNND------------------------FVVDATRKGNKIRFANHSINPNC 709

Query: 298  YAQNALYDHDDKSAPHIMFFACENIPPGQELVYHYNY 188
            YA+  +   D +    I  FA   I PG+EL + Y Y
Sbjct: 710  YAKVMMVTGDHR----IGIFAKRAIQPGEELFFDYRY 742



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>YNCA_CAEEL (P34544) Hypothetical protein R05D3.11 in chromosome III|
          Length = 1327

 Score = 69.3 bits (168), Expect = 1e-11
 Identities = 31/88 (35%), Positives = 46/88 (52%)
 Frame = -1

Query: 367  FAVDASKMGNFAKFINHSCTPNLYAQNALYDHDDKSAPHIMFFACENIPPGQELVYHYNY 188
            + +DA + GN  +F+NHSC PN++ Q+ +YD  D   P + FF  + +  G EL + Y Y
Sbjct: 1242 YVIDAKQRGNLGRFLNHSCDPNVHVQHVMYDTHDLRLPWVAFFTRKYVKAGDELTWDYQY 1301

Query: 187  AIDQVYDENGNIKKKKCLCGSTECDGWL 104
              DQ         +  C CG+  C G L
Sbjct: 1302 TQDQT-----ATTQLTCHCGAENCTGRL 1324



 Score = 66.6 bits (161), Expect = 7e-11
 Identities = 37/100 (37%), Positives = 53/100 (53%), Gaps = 20/100 (20%)
 Frame = -1

Query: 712  RIIEAKPL--VYECGPSCKCP-PTCHNRVGQKGIK----------------FRLQVFKTK 590
            R++ +K +  +YEC   C C   +C+NRV Q  IK                F LQ+FKT 
Sbjct: 1024 RLLSSKVISGLYECNDQCSCHRKSCYNRVVQNNIKYPMHVSLFNDDTYQLLFFLQIFKTA 1083

Query: 589  SMGWGVKTLDYIPSGSFVCEYIGEVLDDEEAQK-RMTDEY 473
              GWGV+ L  IP  +F+C Y+G +L D+ A + R  D+Y
Sbjct: 1084 QSGWGVRALTDIPQSTFICTYVGAILTDDLADELRNADQY 1123



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>TRX_DROVI (Q24742) Protein trithorax|
          Length = 3828

 Score = 69.3 bits (168), Expect = 1e-11
 Identities = 56/196 (28%), Positives = 79/196 (40%)
 Frame = -1

Query: 691  LVYECGPSCKCPPTCHNRVGQKGIKFRLQVFKTKSMGWGVKTLDYIPSGSFVCEYIGEVL 512
            LV   G     P     R  ++  K  + VF++   G G+     I +G  V EY GE++
Sbjct: 3665 LVPRRGTGSNLPMAMKYRTLKETYKDYVGVFRSHIHGRGLYCTKDIEAGEMVIEYAGELI 3724

Query: 511  DDEEAQKRMTDEYLFAIGHNYYDETLWEGLSRSIPSLQNGPGNDEEAGFAVDASKMGNFA 332
                  KR            YYD     G+   +  + +           VDA+  GN A
Sbjct: 3725 RSTLTDKR----------ERYYDS---RGIGCYMFKIDDN--------LVVDATMRGNAA 3763

Query: 331  KFINHSCTPNLYAQNALYDHDDKSAPHIMFFACENIPPGQELVYHYNYAIDQVYDENGNI 152
            +FINHSC PN Y++      D     HI+ FA   I  G+EL Y Y +  +         
Sbjct: 3764 RFINHSCEPNCYSKVV----DILGHKHIIIFALRRIVQGEELTYDYKFPFED-------- 3811

Query: 151  KKKKCLCGSTECDGWL 104
            +K  C CGS  C  +L
Sbjct: 3812 EKIPCSCGSKRCRKYL 3827



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>EZH2_HUMAN (Q15910) Enhancer of zeste homolog 2 (ENX-1)|
          Length = 746

 Score = 69.3 bits (168), Expect = 1e-11
 Identities = 45/158 (28%), Positives = 72/158 (45%), Gaps = 2/158 (1%)
 Frame = -1

Query: 652 TCHNRVGQKGIKFRLQVFKTKSMGWGVKTLDYIPSGSFVCEYIGEVLDDEEAQKR--MTD 479
           +C N   Q+G K  L +  +   GWG+   D +    F+ EY GE++  +EA +R  + D
Sbjct: 600 SCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYD 659

Query: 478 EYLFAIGHNYYDETLWEGLSRSIPSLQNGPGNDEEAGFAVDASKMGNFAKFINHSCTPNL 299
           +Y+ +   N  ++                        F VDA++ GN  +F NHS  PN 
Sbjct: 660 KYMCSFLFNLNND------------------------FVVDATRKGNKIRFANHSVNPNC 695

Query: 298 YAQNALYDHDDKSAPHIMFFACENIPPGQELVYHYNYA 185
           YA+  + + D +    I  FA   I  G+EL + Y Y+
Sbjct: 696 YAKVMMVNGDHR----IGIFAKRAIQTGEELFFDYRYS 729



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>EZH1_MOUSE (P70351) Enhancer of zeste homolog 1 (ENX-2)|
          Length = 747

 Score = 69.3 bits (168), Expect = 1e-11
 Identities = 50/175 (28%), Positives = 78/175 (44%), Gaps = 6/175 (3%)
 Frame = -1

Query: 691  LVYECGPS----CKCPPTCHNRVGQKGIKFRLQVFKTKSMGWGVKTLDYIPSGSFVCEYI 524
            L   CG S    CK   +C N   Q+G+K  L +  +   GWG    + +    F+ EY 
Sbjct: 585  LCLTCGASEHWDCKVV-SCKNCSIQRGLKKHLLLAPSDVAGWGTFIKESVQKNEFISEYC 643

Query: 523  GEVLDDEEAQKR--MTDEYLFAIGHNYYDETLWEGLSRSIPSLQNGPGNDEEAGFAVDAS 350
            GE++  +EA +R  + D+Y+ +   N  ++                        F VDA+
Sbjct: 644  GELISQDEADRRGKVYDKYMSSFLFNLNND------------------------FVVDAT 679

Query: 349  KMGNFAKFINHSCTPNLYAQNALYDHDDKSAPHIMFFACENIPPGQELVYHYNYA 185
            + GN  +F NHS  PN YA+  + + D +    I  FA   I  G+EL + Y Y+
Sbjct: 680  RKGNKIRFANHSVNPNCYAKVVMVNGDHR----IGIFAKRAIQAGEELFFDYRYS 730



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>EZH1_HUMAN (Q92800) Enhancer of zeste homolog 1 (ENX-2)|
          Length = 747

 Score = 69.3 bits (168), Expect = 1e-11
 Identities = 50/175 (28%), Positives = 78/175 (44%), Gaps = 6/175 (3%)
 Frame = -1

Query: 691  LVYECGPS----CKCPPTCHNRVGQKGIKFRLQVFKTKSMGWGVKTLDYIPSGSFVCEYI 524
            L   CG S    CK   +C N   Q+G+K  L +  +   GWG    + +    F+ EY 
Sbjct: 585  LCLTCGASEHWDCKVV-SCKNCSIQRGLKKHLLLAPSDVAGWGTFIKESVQKNEFISEYC 643

Query: 523  GEVLDDEEAQKR--MTDEYLFAIGHNYYDETLWEGLSRSIPSLQNGPGNDEEAGFAVDAS 350
            GE++  +EA +R  + D+Y+ +   N  ++                        F VDA+
Sbjct: 644  GELISQDEADRRGKVYDKYMSSFLFNLNND------------------------FVVDAT 679

Query: 349  KMGNFAKFINHSCTPNLYAQNALYDHDDKSAPHIMFFACENIPPGQELVYHYNYA 185
            + GN  +F NHS  PN YA+  + + D +    I  FA   I  G+EL + Y Y+
Sbjct: 680  RKGNKIRFANHSVNPNCYAKVVMVNGDHR----IGIFAKRAIQAGEELFFDYRYS 730



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>SUVR3_ARATH (Q9SRV2) Histone-lysine N-methyltransferase SUVR3 (EC 2.1.1.43)|
           (Suppressor of variegation 3-9-related protein 3)
           (Su(var)3-9-related protein 3) (Protein SET DOMAIN GROUP
           20)
          Length = 338

 Score = 68.2 bits (165), Expect = 3e-11
 Identities = 51/193 (26%), Positives = 80/193 (41%)
 Frame = -1

Query: 682 ECGPSCKCPPTCHNRVGQKGIKFRLQVFKTKSMGWGVKTLDYIPSGSFVCEYIGEVLDDE 503
           ECG  C C   C NRV QKG+   L++ + +  GW              C Y  +++   
Sbjct: 169 ECGSGCGCGSDCSNRVTQKGVSVSLKIVRDEKKGW--------------CLYADQLIKQG 214

Query: 502 EAQKRMTDEYLFAIGHNYYDETLWEGLSRSIPSLQNGPGNDEEAGFAVDASKMGNFAKFI 323
             ++ + D+            +     S  +   ++ P         +DA+++GN A+FI
Sbjct: 215 HRRQNIYDKL----------RSTQSFASALLVVREHLPSGQACLRINIDATRIGNVARFI 264

Query: 322 NHSCTPNLYAQNALYDHDDKSAPHIMFFACENIPPGQELVYHYNYAIDQVYDENGNIKKK 143
           NHSC         L        P + FFA ++I   +EL   ++Y    V  EN +  K 
Sbjct: 265 NHSCDGG-NLSTVLLRSSGALLPRLCFFAAKDIIAEEEL--SFSYGDVSVAGENRD-DKL 320

Query: 142 KCLCGSTECDGWL 104
            C CGS+ C G L
Sbjct: 321 NCSCGSSCCLGTL 333



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>TRX_DROME (P20659) Protein trithorax|
          Length = 3726

 Score = 67.4 bits (163), Expect = 4e-11
 Identities = 55/196 (28%), Positives = 78/196 (39%)
 Frame = -1

Query: 691  LVYECGPSCKCPPTCHNRVGQKGIKFRLQVFKTKSMGWGVKTLDYIPSGSFVCEYIGEVL 512
            LV   G     P     R  ++  K  + VF++   G G+     I +G  V EY GE++
Sbjct: 3563 LVPRRGTGSNLPMAMKYRTLKETYKDYVGVFRSHIHGRGLYCTKDIEAGEMVIEYAGELI 3622

Query: 511  DDEEAQKRMTDEYLFAIGHNYYDETLWEGLSRSIPSLQNGPGNDEEAGFAVDASKMGNFA 332
                  KR            YYD     G+   +  + +           VDA+  GN A
Sbjct: 3623 RSTLTDKR----------ERYYDS---RGIGCYMFKIDDN--------LVVDATMRGNAA 3661

Query: 331  KFINHSCTPNLYAQNALYDHDDKSAPHIMFFACENIPPGQELVYHYNYAIDQVYDENGNI 152
            +FINH C PN Y++      D     HI+ FA   I  G+EL Y Y +  +         
Sbjct: 3662 RFINHCCEPNCYSKVV----DILGHKHIIIFAVRRIVQGEELTYDYKFPFED-------- 3709

Query: 151  KKKKCLCGSTECDGWL 104
            +K  C CGS  C  +L
Sbjct: 3710 EKIPCSCGSKRCRKYL 3725



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>EZH2_MOUSE (Q61188) Enhancer of zeste homolog 2 (ENX-1)|
          Length = 746

 Score = 67.0 bits (162), Expect = 6e-11
 Identities = 43/158 (27%), Positives = 73/158 (46%), Gaps = 2/158 (1%)
 Frame = -1

Query: 652 TCHNRVGQKGIKFRLQVFKTKSMGWGVKTLDYIPSGSFVCEYIGEVL--DDEEAQKRMTD 479
           +C N   Q+G K  L +  +   GWG+   D +    F+ EY GE++  D+++ + ++ D
Sbjct: 600 SCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEDDRRGKVYD 659

Query: 478 EYLFAIGHNYYDETLWEGLSRSIPSLQNGPGNDEEAGFAVDASKMGNFAKFINHSCTPNL 299
           +Y+ +   N  ++                        F VDA++ GN  +F NHS  PN 
Sbjct: 660 KYMCSFLFNLNND------------------------FVVDATRKGNKIRFANHSVNPNC 695

Query: 298 YAQNALYDHDDKSAPHIMFFACENIPPGQELVYHYNYA 185
           YA+  + + D +    I  FA   I  G+EL + Y Y+
Sbjct: 696 YAKVMMVNGDHR----IGIFAKRAIQTGEELFFDYRYS 729



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>MLL2_HUMAN (O14686) Myeloid/lymphoid or mixed-lineage leukemia protein 2|
            (ALL1-related protein)
          Length = 5262

 Score = 66.2 bits (160), Expect = 1e-10
 Identities = 47/172 (27%), Positives = 79/172 (45%)
 Frame = -1

Query: 619  KFRLQVFKTKSMGWGVKTLDYIPSGSFVCEYIGEVLDDEEAQKRMTDEYLFAIGHNYYDE 440
            K  + + +++  G G+     +   + V EYIG ++ +E A +R               E
Sbjct: 5121 KNNVYLARSRIQGLGLYAAKDLEKHTMVIEYIGTIIRNEVANRR---------------E 5165

Query: 439  TLWEGLSRSIPSLQNGPGNDEEAGFAVDASKMGNFAKFINHSCTPNLYAQNALYDHDDKS 260
             ++E  +R I   +    N+E     +DA+  G  A++INHSC PN  A+   +D +DK 
Sbjct: 5166 KIYEEQNRGIYMFRI---NNEHV---IDATLTGGPARYINHSCAPNCVAEVVTFDKEDK- 5218

Query: 259  APHIMFFACENIPPGQELVYHYNYAIDQVYDENGNIKKKKCLCGSTECDGWL 104
               I+  +   IP G+EL Y Y +  +   D+   I    C CG+  C  W+
Sbjct: 5219 ---IIIISSRRIPKGEELTYDYQFDFE---DDQHEI---PCHCGAWNCRKWM 5261



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>HRX_HUMAN (Q03164) Zinc finger protein HRX (ALL-1) (Trithorax-like protein)|
          Length = 3969

 Score = 66.2 bits (160), Expect = 1e-10
 Identities = 53/176 (30%), Positives = 79/176 (44%)
 Frame = -1

Query: 631  QKGIKFRLQVFKTKSMGWGVKTLDYIPSGSFVCEYIGEVLDDEEAQKRMTDEYLFAIGHN 452
            +K  K  + V+++   G G+     I +G  V EY G V+   +  KR            
Sbjct: 3824 KKTSKEAVGVYRSPIHGRGLFCKRNIDAGEMVIEYAGNVIRSIQTDKR----------EK 3873

Query: 451  YYDETLWEGLSRSIPSLQNGPGNDEEAGFAVDASKMGNFAKFINHSCTPNLYAQNALYDH 272
            YYD    +G+   +  +     +D E    VDA+  GN A+FINHSC PN Y++    D 
Sbjct: 3874 YYDS---KGIGCYMFRI-----DDSEV---VDATMHGNAARFINHSCEPNCYSRVINID- 3921

Query: 271  DDKSAPHIMFFACENIPPGQELVYHYNYAIDQVYDENGNIKKKKCLCGSTECDGWL 104
                  HI+ FA   I  G+EL Y Y + I+   +      K  C CG+ +C  +L
Sbjct: 3922 ---GQKHIVIFAMRKIYRGEELTYDYKFPIEDASN------KLPCNCGAKKCRKFL 3968



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>HRX_MOUSE (P55200) Zinc finger protein HRX (ALL-1) (Fragment)|
          Length = 3866

 Score = 66.2 bits (160), Expect = 1e-10
 Identities = 53/176 (30%), Positives = 79/176 (44%)
 Frame = -1

Query: 631  QKGIKFRLQVFKTKSMGWGVKTLDYIPSGSFVCEYIGEVLDDEEAQKRMTDEYLFAIGHN 452
            +K  K  + V+++   G G+     I +G  V EY G V+   +  KR            
Sbjct: 3721 KKTSKEAVGVYRSPIHGRGLFCKRNIDAGEMVIEYAGNVIRSIQTDKR----------EK 3770

Query: 451  YYDETLWEGLSRSIPSLQNGPGNDEEAGFAVDASKMGNFAKFINHSCTPNLYAQNALYDH 272
            YYD    +G+   +  +     +D E    VDA+  GN A+FINHSC PN Y++    D 
Sbjct: 3771 YYDS---KGIGCYMFRI-----DDSEV---VDATMHGNAARFINHSCEPNCYSRVINID- 3818

Query: 271  DDKSAPHIMFFACENIPPGQELVYHYNYAIDQVYDENGNIKKKKCLCGSTECDGWL 104
                  HI+ FA   I  G+EL Y Y + I+   +      K  C CG+ +C  +L
Sbjct: 3819 ---GQKHIVIFAMRKIYRGEELTYDYKFPIEDASN------KLPCNCGAKKCRKFL 3865



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>SET1_SCHPO (Q9Y7R4) Histone-lysine N-methyltransferase, H3 lysine-4 specific (EC|
            2.1.1.43) (Set1 complex component set1) (Set1C component
            set1) (COMPASS component set1) (SET domain-containing
            protein 1) (Spset1)
          Length = 920

 Score = 65.5 bits (158), Expect = 2e-10
 Identities = 48/158 (30%), Positives = 68/158 (43%)
 Frame = -1

Query: 577  GVKTLDYIPSGSFVCEYIGEVLDDEEAQKRMTDEYLFAIGHNYYDETLWEGLSRSIPSLQ 398
            G+  ++ I     V EYIGE++    A  R  +     IG +Y                 
Sbjct: 794  GLFAMENIDKNDMVIEYIGEIIRQRVADNREKNYVREGIGDSYLFRI------------- 840

Query: 397  NGPGNDEEAGFAVDASKMGNFAKFINHSCTPNLYAQNALYDHDDKSAPHIMFFACENIPP 218
                 DE+    VDA+K GN A+FINHSC PN  A+    +   K    I+ +A  +I  
Sbjct: 841  -----DEDV--IVDATKKGNIARFINHSCAPNCIARIIRVEGKRK----IVIYADRDIMH 889

Query: 217  GQELVYHYNYAIDQVYDENGNIKKKKCLCGSTECDGWL 104
            G+EL Y Y +  +          K  CLCG+  C G+L
Sbjct: 890  GEELTYDYKFPEE--------ADKIPCLCGAPTCRGYL 919



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>SET1A_HUMAN (O15047) Histone-lysine N-methyltransferase, H3 lysine-4 specific|
            SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase
            complex subunit SET1) (SET-domain-containing protein 1A)
          Length = 1707

 Score = 64.7 bits (156), Expect = 3e-10
 Identities = 47/180 (26%), Positives = 77/180 (42%), Gaps = 8/180 (4%)
 Frame = -1

Query: 619  KFRLQVFKTKSMGWGVKTLDYIPSGSFVCEYIGE-----VLDDEE---AQKRMTDEYLFA 464
            K +L+  +++   WG+  ++ I +   V EY+G+     V D  E    Q+ +   YLF 
Sbjct: 1567 KKKLRFGRSRIHEWGLFAMEPIAADEMVIEYVGQNIRQMVADMREKRYVQEGIGSSYLFR 1626

Query: 463  IGHNYYDETLWEGLSRSIPSLQNGPGNDEEAGFAVDASKMGNFAKFINHSCTPNLYAQNA 284
            + H+                              +DA+K GN A+FINH CTPN YA+  
Sbjct: 1627 VDHDTI----------------------------IDATKCGNLARFINHCCTPNCYAKVI 1658

Query: 283  LYDHDDKSAPHIMFFACENIPPGQELVYHYNYAIDQVYDENGNIKKKKCLCGSTECDGWL 104
              +   K    I+ ++ + I   +E+ Y Y + ++          K  CLCG+  C G L
Sbjct: 1659 TIESQKK----IVIYSKQPIGVDEEITYDYKFPLED--------NKIPCLCGTESCRGSL 1706



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>SET1_YEAST (P38827) Histone-lysine N-methyltransferase, H3 lysine-4 specific (EC|
            2.1.1.43) (COMPASS component SET1) (SET domain protein 1)
          Length = 1080

 Score = 61.6 bits (148), Expect = 2e-09
 Identities = 44/159 (27%), Positives = 65/159 (40%)
 Frame = -1

Query: 580  WGVKTLDYIPSGSFVCEYIGEVLDDEEAQKRMTDEYLFAIGHNYYDETLWEGLSRSIPSL 401
            WG+  LD I +   + EY+GE +    A+ R        IG +Y                
Sbjct: 950  WGLYALDSIAAKEMIIEYVGERIRQPVAEMREKRYLKNGIGSSYLFRV------------ 997

Query: 400  QNGPGNDEEAGFAVDASKMGNFAKFINHSCTPNLYAQNALYDHDDKSAPHIMFFACENIP 221
                  DE     +DA+K G  A+FINH C PN  A+             I+ +A  +I 
Sbjct: 998  ------DENT--VIDATKKGGIARFINHCCDPNCTAKIIKVG----GRRRIVIYALRDIA 1045

Query: 220  PGQELVYHYNYAIDQVYDENGNIKKKKCLCGSTECDGWL 104
              +EL Y Y +       E  + ++  CLCG+  C G+L
Sbjct: 1046 ASEELTYDYKFE-----REKDDEERLPCLCGAPNCKGFL 1079



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>ATX4_ARATH (Q9SUE7) Histone-lysine N-methyltransferase ATX4 (EC 2.1.1.43)|
            (Trithorax-homolog protein 4) (TRX-homolog protein 4)
            (Trithorax 4) (Protein SET DOMAIN GROUP 16)
          Length = 990

 Score = 60.8 bits (146), Expect = 4e-09
 Identities = 51/163 (31%), Positives = 67/163 (41%), Gaps = 7/163 (4%)
 Frame = -1

Query: 583  GWGVKTLDYIPSGSFVCEYIGE-----VLDDEEAQKRMT--DEYLFAIGHNYYDETLWEG 425
            GWG+     I  G  V EY GE     + D  EA+ R    D YLF I            
Sbjct: 859  GWGLFARRNIQEGEMVLEYRGEQVRGSIADLREARYRRVGKDCYLFKISEEV-------- 910

Query: 424  LSRSIPSLQNGPGNDEEAGFAVDASKMGNFAKFINHSCTPNLYAQNALYDHDDKSAPHIM 245
                                 VDA+  GN A+ INHSCTPN YA+  +   D++S   I+
Sbjct: 911  --------------------VVDATDKGNIARLINHSCTPNCYAR-IMSVGDEES--RIV 947

Query: 244  FFACENIPPGQELVYHYNYAIDQVYDENGNIKKKKCLCGSTEC 116
              A  N+  G+EL Y Y +  D+  +      K  CLC +  C
Sbjct: 948  LIAKANVAVGEELTYDYLFDPDEAEE-----LKVPCLCKAPNC 985



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>MEDEA_ARATH (O65312) Polycomb group protein MEDEA (Maternal embryogenesis control|
            protein) (Protein FERTILIZATION-INDEPENDENT SEED1)
            (Protein SET DOMAIN GROUP 5)
          Length = 689

 Score = 59.7 bits (143), Expect = 9e-09
 Identities = 54/202 (26%), Positives = 83/202 (41%), Gaps = 22/202 (10%)
 Frame = -1

Query: 682  ECGPS-CK-CPPTCHN--------RVGQKGIKFRLQ------VFKTKSMGWGVKTLDYIP 551
            EC P  C+ CP +C +        ++  K ++F LQ      + K+   GWG  T D + 
Sbjct: 506  ECDPDLCRSCPLSCGDGTLGETPVQIQCKNMQFLLQTNKKILIGKSDVHGWGAFTWDSLK 565

Query: 550  SGSFVCEYIGEVLDDEEAQKR------MTDEYLFAIGHNYYDETLWEGLSRSIPSLQNGP 389
               ++ EY GE++  +EA +R      +   YLF +                        
Sbjct: 566  KNEYLGEYTGELITHDEANERGRIEDRIGSSYLFTL------------------------ 601

Query: 388  GNDEEAGFAVDASKMGNFAKFINHSCTPNLYAQNALYDHDDKSAPHIMFFACENIPPGQE 209
             ND+     +DA + GN  KF+NHS  PN YA+  +   D +    I  FA   I  G+E
Sbjct: 602  -NDQ---LEIDARRKGNEFKFLNHSARPNCYAKLMIVRGDQR----IGLFAERAIEEGEE 653

Query: 208  LVYHYNYAIDQVYDENGNIKKK 143
            L + Y Y  +      G   +K
Sbjct: 654  LFFDYCYGPEHADWSRGREPRK 675



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>SUVHA_ARATH (Q3EC60) Putative histone-lysine N-methyltransferase, H3 lysine-9|
           specific SUVH10 (EC 2.1.1.43) (Histone H3-K9
           methyltransferase 10) (H3-K9-HMTase 10) (Suppressor of
           variegation 3-9 homolog protein 10) (Su(var)3-9 homolog
           protein 10) (Protein
          Length = 312

 Score = 59.7 bits (143), Expect = 9e-09
 Identities = 31/88 (35%), Positives = 48/88 (54%)
 Frame = -1

Query: 373 AGFAVDASKMGNFAKFINHSCTPNLYAQNALYDHDDKSAPHIMFFACENIPPGQELVYHY 194
           +   + A K GN A+F+NHSC+PN++ Q+   + +     +I FFA ++IPP  EL Y Y
Sbjct: 230 SSLVISAKKSGNVARFMNHSCSPNVFWQSIAREQNGLWCLYIGFFAMKHIPPLTELRYDY 289

Query: 193 NYAIDQVYDENGNIKKKKCLCGSTECDG 110
                    ++    KK CLC + +C G
Sbjct: 290 G--------KSRGGGKKMCLCRTKKCCG 309



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>MLL3_HUMAN (Q8NEZ4) Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog|
            (Histone-lysine N-methyltransferase, H3 lysine-4 specific
            MLL3) (EC 2.1.1.43) (Homologous to ALR protein)
          Length = 4911

 Score = 59.3 bits (142), Expect = 1e-08
 Identities = 44/172 (25%), Positives = 74/172 (43%)
 Frame = -1

Query: 619  KFRLQVFKTKSMGWGVKTLDYIPSGSFVCEYIGEVLDDEEAQKRMTDEYLFAIGHNYYDE 440
            K  + + +++  G G+     I   + V EYIG ++ +E A ++               E
Sbjct: 4770 KSNVYLARSRIQGLGLYAARDIEKHTMVIEYIGTIIRNEVANRK---------------E 4814

Query: 439  TLWEGLSRSIPSLQNGPGNDEEAGFAVDASKMGNFAKFINHSCTPNLYAQNALYDHDDKS 260
             L+E  +R +   +    ND      +DA+  G  A++INHSC PN  A+   ++   K 
Sbjct: 4815 KLYESQNRGVYMFRMD--NDH----VIDATLTGGPARYINHSCAPNCVAEVVTFERGHK- 4867

Query: 259  APHIMFFACENIPPGQELVYHYNYAIDQVYDENGNIKKKKCLCGSTECDGWL 104
               I+  +   I  G+EL Y Y       +D   +  K  C CG+  C  W+
Sbjct: 4868 ---IIISSSRRIQKGEELCYDYK------FDFEDDQHKIPCHCGAVNCRKWM 4910



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>MLL3_MOUSE (Q8BRH4) Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog|
            (Histone-lysine N-methyltransferase, H3 lysine-4 specific
            MLL3) (EC 2.1.1.43)
          Length = 4903

 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 44/172 (25%), Positives = 74/172 (43%)
 Frame = -1

Query: 619  KFRLQVFKTKSMGWGVKTLDYIPSGSFVCEYIGEVLDDEEAQKRMTDEYLFAIGHNYYDE 440
            K  + + +++  G G+     I   + V EYIG ++ +E A ++               E
Sbjct: 4762 KSNVYLARSRIQGLGLYAARDIEKHTMVIEYIGTIIRNEVANRK---------------E 4806

Query: 439  TLWEGLSRSIPSLQNGPGNDEEAGFAVDASKMGNFAKFINHSCTPNLYAQNALYDHDDKS 260
             L+E  +R +   +    ND      +DA+  G  A++INHSC PN  A+   ++   K 
Sbjct: 4807 KLYESQNRGVYMFRMD--NDH----VIDATLTGGPARYINHSCAPNCVAEVVTFERGHK- 4859

Query: 259  APHIMFFACENIPPGQELVYHYNYAIDQVYDENGNIKKKKCLCGSTECDGWL 104
               I+  +   I  G+EL Y Y       +D   +  K  C CG+  C  W+
Sbjct: 4860 ---IIISSNRRIQKGEELCYDYK------FDFEDDQHKIPCHCGAVNCRKWM 4902



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>MLL4_HUMAN (Q9UMN6) Myeloid/lymphoid or mixed-lineage leukemia protein 4|
            (Trithorax homolog 2)
          Length = 2715

 Score = 57.4 bits (137), Expect = 4e-08
 Identities = 52/189 (27%), Positives = 81/189 (42%)
 Frame = -1

Query: 670  SCKCPPTCHNRVGQKGIKFRLQVFKTKSMGWGVKTLDYIPSGSFVCEYIGEVLDDEEAQK 491
            S + P     R  +K  K  + V+++   G G+     I +G  V EY G V+      K
Sbjct: 2557 SLELPMAMRFRHLKKTSKEAVGVYRSAIHGRGLFCKRNIDAGEMVIEYSGIVIRSVLTDK 2616

Query: 490  RMTDEYLFAIGHNYYDETLWEGLSRSIPSLQNGPGNDEEAGFAVDASKMGNFAKFINHSC 311
            R            +YD    +G+   +  + +           VDA+  GN A+FINHSC
Sbjct: 2617 R----------EKFYDG---KGIGCYMFRMDDFD--------VVDATMHGNAARFINHSC 2655

Query: 310  TPNLYAQNALYDHDDKSAPHIMFFACENIPPGQELVYHYNYAIDQVYDENGNIKKKKCLC 131
             PN +++  ++    K   HI+ FA   I  G+EL Y Y + I+   +      K  C C
Sbjct: 2656 EPNCFSR-VIHVEGQK---HIVIFALRRILRGEELTYDYKFPIEDASN------KLPCNC 2705

Query: 130  GSTECDGWL 104
            G+  C  +L
Sbjct: 2706 GAKRCRRFL 2714



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>ATX1_ARATH (Q9C5X4) Histone-lysine N-methyltransferase, H3 lysine-4 specific|
            ATX1 (EC 2.1.1.43) (H3-K4-HMTase) (Trithorax-homolog
            protein 1) (TRX-homolog protein 1) (Protein SET DOMAIN
            GROUP 27)
          Length = 1062

 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 47/169 (27%), Positives = 72/169 (42%), Gaps = 1/169 (0%)
 Frame = -1

Query: 613  RLQVFKTKSMGWGVKTLDYIPSGSFVCEYIGEVLDDEEAQKRMTDEYLFAIGHNYYDETL 434
            RL   K+   G+G+       +G  + EY GE++    A KR    Y   +G   Y   +
Sbjct: 899  RLAFGKSGIHGFGIFAKLPHRAGDMMIEYTGELVRPSIADKREQLIYNSMVGAGTYMFRI 958

Query: 433  WEGLSRSIPSLQNGPGNDEEAGFAVDASKMGNFAKFINHSCTPNLYAQNALYDHDDKSAP 254
                             D+E    +DA++ G+ A  INHSC PN Y++    + D+    
Sbjct: 959  -----------------DDER--VIDATRTGSIAHLINHSCVPNCYSRVITVNGDE---- 995

Query: 253  HIMFFACENIPPGQELVYHYN-YAIDQVYDENGNIKKKKCLCGSTECDG 110
            HI+ FA  +IP  +EL Y Y  ++I +         +  C CG   C G
Sbjct: 996  HIIIFAKRHIPKWEELTYDYRFFSIGE---------RLSCSCGFPGCRG 1035



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>ATX2_ARATH (Q9MA43) Histone-lysine N-methyltransferase ATX2 (EC 2.1.1.43)|
            (Trithorax-homolog protein 2) (TRX-homolog protein 2)
            (Protein SET DOMAIN GROUP 30)
          Length = 1193

 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 47/169 (27%), Positives = 71/169 (42%), Gaps = 1/169 (0%)
 Frame = -1

Query: 613  RLQVFKTKSMGWGVKTLDYIPSGSFVCEYIGEVLDDEEAQKRMTDEYLFAIGHNYYDETL 434
            RL   K+   G+G+       +G  V EY GE++    A KR    Y   +G   Y   +
Sbjct: 897  RLAFGKSGIHGFGIFAKLPHRAGDMVIEYTGELVRPPIADKREHLIYNSMVGAGTYMFRI 956

Query: 433  WEGLSRSIPSLQNGPGNDEEAGFAVDASKMGNFAKFINHSCTPNLYAQNALYDHDDKSAP 254
                             D E    +DA++ G+ A  INHSC PN Y++    + D+    
Sbjct: 957  -----------------DNER--VIDATRTGSIAHLINHSCEPNCYSRVISVNGDE---- 993

Query: 253  HIMFFACENIPPGQELVYHYN-YAIDQVYDENGNIKKKKCLCGSTECDG 110
            HI+ FA  ++   +EL Y Y  ++ID+         +  C CG   C G
Sbjct: 994  HIIIFAKRDVAKWEELTYDYRFFSIDE---------RLACYCGFPRCRG 1033



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>ATX5_ARATH (Q8GZ42) Histone-lysine N-methyltransferase ATX5 (EC 2.1.1.43)|
            (Trithorax-homolog protein 5) (TRX-homolog protein 5)
            (Protein SET DOMAIN GROUP 29)
          Length = 1043

 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 52/163 (31%), Positives = 66/163 (40%), Gaps = 7/163 (4%)
 Frame = -1

Query: 583  GWGVKTLDYIPSGSFVCEYIGE-----VLDDEEAQKRMT--DEYLFAIGHNYYDETLWEG 425
            GWG+     I  G  V EY GE     + D  EA+ R    D YLF I            
Sbjct: 912  GWGLFARRNIQEGEMVLEYRGEQVRGIIADLREARYRREGKDCYLFKISEEV-------- 963

Query: 424  LSRSIPSLQNGPGNDEEAGFAVDASKMGNFAKFINHSCTPNLYAQNALYDHDDKSAPHIM 245
                                 VDA++ GN A+ INHSC PN YA+  +   DD+S   I+
Sbjct: 964  --------------------VVDATEKGNIARLINHSCMPNCYAR-IMSVGDDES--RIV 1000

Query: 244  FFACENIPPGQELVYHYNYAIDQVYDENGNIKKKKCLCGSTEC 116
              A   +   +EL Y Y +  D+  DE     K  CLC S  C
Sbjct: 1001 LIAKTTVASCEELTYDYLFDPDEP-DE----FKVPCLCKSPNC 1038



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>EZA1_ARATH (Q9ZSM8) Probable Polycomb group protein EZA1 (CURLY LEAF-like 1)|
            (Protein SET DOMAIN GROUP 10)
          Length = 856

 Score = 54.7 bits (130), Expect = 3e-07
 Identities = 40/152 (26%), Positives = 58/152 (38%), Gaps = 6/152 (3%)
 Frame = -1

Query: 613  RLQVFKTKSMGWGVKTLDYIPSGSFVCEYIGEVLDDEEAQKR------MTDEYLFAIGHN 452
            R+ + K+   GWG    + +    ++ EY GE++   EA KR          +LF +   
Sbjct: 708  RILLGKSDVAGWGAFLKNSVSKNEYLGEYTGELISHHEADKRGKIYDRANSSFLFDLNDQ 767

Query: 451  YYDETLWEGLSRSIPSLQNGPGNDEEAGFAVDASKMGNFAKFINHSCTPNLYAQNALYDH 272
            Y                             +DA + G+  KF NHS  PN YA+      
Sbjct: 768  Y----------------------------VLDAQRKGDKLKFANHSAKPNCYAKVMFVAG 799

Query: 271  DDKSAPHIMFFACENIPPGQELVYHYNYAIDQ 176
            D +    +  FA E I   +EL Y Y Y  DQ
Sbjct: 800  DHR----VGIFANERIEASEELFYDYRYGPDQ 827



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>MES2_CAEEL (O17514) Polycomb protein mes-2 (Maternal-effect sterile protein 2)|
            (E(z) homolog)
          Length = 773

 Score = 53.9 bits (128), Expect = 5e-07
 Identities = 48/180 (26%), Positives = 75/180 (41%), Gaps = 13/180 (7%)
 Frame = -1

Query: 685  YECGPS----CKCPPT------CHNRVGQKGIKFRLQVFKTKSMGWGVKTLDYIPSGSFV 536
            +EC P     CKC         C N    + I+ R     +K  G G+  L+      F+
Sbjct: 588  WECNPMTCNMCKCDAIDSNIIKCRNFGMTRMIQKRTYCGPSKIAGNGLFLLEPAEKDEFI 647

Query: 535  CEYIGEVLDDEEAQKR--MTDEYLFAIGHNYYDETLWEGLSRSIPSLQNGPGNDEEAGFA 362
             EY GE + D+EA++R  + D Y  +   N                         E G A
Sbjct: 648  TEYTGERISDDEAERRGAIYDRYQCSYIFNI------------------------ETGGA 683

Query: 361  VDASKMGNFAKFINH-SCTPNLYAQNALYDHDDKSAPHIMFFACENIPPGQELVYHYNYA 185
            +D+ K+GN A+F NH S  P  YA+  +   + +    I F+A   +   +EL + Y+Y+
Sbjct: 684  IDSYKIGNLARFANHDSKNPTCYARTMVVAGEHR----IGFYAKRRLEISEELTFDYSYS 739



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>EZ1_MAIZE (Q8S4P6) Polycomb protein EZ1 (Enhancer of zeste protein 1)|
          Length = 931

 Score = 53.9 bits (128), Expect = 5e-07
 Identities = 42/146 (28%), Positives = 66/146 (45%)
 Frame = -1

Query: 613  RLQVFKTKSMGWGVKTLDYIPSGSFVCEYIGEVLDDEEAQKRMTDEYLFAIGHNYYDETL 434
            R+ + ++   GWG    + +    ++ EY GE++  +EA KR         G  Y  E  
Sbjct: 779  RVLLGRSDVSGWGAFLKNSVSKHEYLGEYTGELISHKEADKR---------GKIYDREN- 828

Query: 433  WEGLSRSIPSLQNGPGNDEEAGFAVDASKMGNFAKFINHSCTPNLYAQNALYDHDDKSAP 254
                S  + +L N         + +DA +MG+  KF NH+  PN YA+  +   D +   
Sbjct: 829  ----SSFLFNLNNE--------YVLDAYRMGDKLKFANHAPDPNCYAKVIMVTGDHR--- 873

Query: 253  HIMFFACENIPPGQELVYHYNYAIDQ 176
             +  FA E I  G+EL Y Y Y  D+
Sbjct: 874  -VGIFAKERILAGEELFYDYRYEPDR 898



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>EZ2_MAIZE (Q8S4P5) Polycomb protein EZ2 (Enhancer of zeste protein 2)|
          Length = 894

 Score = 53.1 bits (126), Expect = 8e-07
 Identities = 39/152 (25%), Positives = 61/152 (40%), Gaps = 6/152 (3%)
 Frame = -1

Query: 613  RLQVFKTKSMGWGVKTLDYIPSGSFVCEYIGEVLDDEEAQKR------MTDEYLFAIGHN 452
            R+ + ++   GWG    + +    ++ EY GE++  +EA KR          +LF +   
Sbjct: 747  RILLGRSDVAGWGAFIKNPVNKNDYLGEYTGELISHKEADKRGKIYDRANSSFLFDLNDQ 806

Query: 451  YYDETLWEGLSRSIPSLQNGPGNDEEAGFAVDASKMGNFAKFINHSCTPNLYAQNALYDH 272
            Y                             +DA + G+  KF NHS  PN YA+  L   
Sbjct: 807  Y----------------------------VLDAYRKGDKLKFANHSSNPNCYAKVMLVAG 838

Query: 271  DDKSAPHIMFFACENIPPGQELVYHYNYAIDQ 176
            D +    +  +A E+I   +EL Y Y Y  DQ
Sbjct: 839  DHR----VGIYAKEHIEASEELFYDYRYGPDQ 866



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>EZ3_MAIZE (Q8S4P4) Polycomb protein EZ3 (Enhancer of zeste protein 3)|
          Length = 895

 Score = 53.1 bits (126), Expect = 8e-07
 Identities = 39/152 (25%), Positives = 61/152 (40%), Gaps = 6/152 (3%)
 Frame = -1

Query: 613  RLQVFKTKSMGWGVKTLDYIPSGSFVCEYIGEVLDDEEAQKR------MTDEYLFAIGHN 452
            R+ + ++   GWG    + +    ++ EY GE++  +EA KR          +LF +   
Sbjct: 748  RILLGRSDVAGWGAFIKNPVNKNDYLGEYTGELISHKEADKRGKIYDRANSSFLFDLNDQ 807

Query: 451  YYDETLWEGLSRSIPSLQNGPGNDEEAGFAVDASKMGNFAKFINHSCTPNLYAQNALYDH 272
            Y                             +DA + G+  KF NHS  PN YA+  L   
Sbjct: 808  Y----------------------------VLDAYRKGDKLKFANHSSNPNCYAKVMLVAG 839

Query: 271  DDKSAPHIMFFACENIPPGQELVYHYNYAIDQ 176
            D +    +  +A E+I   +EL Y Y Y  DQ
Sbjct: 840  DHR----VGIYAKEHIEASEELFYDYRYGPDQ 867



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>CLF_ARATH (P93831) Polycomb group protein CURLY LEAF (Protein INCURVATA 1)|
            (Protein photoperiod insensitive flowering) (Protein SET
            DOMAIN GROUP 1)
          Length = 902

 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 41/136 (30%), Positives = 58/136 (42%)
 Frame = -1

Query: 583  GWGVKTLDYIPSGSFVCEYIGEVLDDEEAQKRMTDEYLFAIGHNYYDETLWEGLSRSIPS 404
            GWG    + +    ++ EY GE++  +EA KR             YD      L      
Sbjct: 763  GWGAFLKNSVSKHEYLGEYTGELISHKEADKR----------GKIYDRENCSFLFNL--- 809

Query: 403  LQNGPGNDEEAGFAVDASKMGNFAKFINHSCTPNLYAQNALYDHDDKSAPHIMFFACENI 224
                  ND+   F +DA + G+  KF NHS  PN YA+  +   D +    +  FA E I
Sbjct: 810  ------NDQ---FVLDAYRKGDKLKFANHSPEPNCYAKVIMVAGDHR----VGIFAKERI 856

Query: 223  PPGQELVYHYNYAIDQ 176
              G+EL Y Y Y  D+
Sbjct: 857  LAGEELFYDYRYEPDR 872



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>LIN59_CAEEL (O44757) Protein lin-59 (Abnormal cell lineage protein 59)|
          Length = 1312

 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 49/201 (24%), Positives = 77/201 (38%), Gaps = 7/201 (3%)
 Frame = -1

Query: 697  KPLVYECGPSCKCPPTCHNRVGQKGIKFRLQVFKTKSMGWGVKTLDYIPSGSFVCEYIGE 518
            + L  +C   C  P   + R  ++    +L V         +KT     +G F+CEY GE
Sbjct: 611  RALRVQCSSDCSVPYCSNRRFWKEDCGNKLCVSNGPRSKRVLKTKIARRAGEFLCEYAGE 670

Query: 517  VLDDEEAQKRMT---DEYLFAIGHNYYDETLWEGLSRSIPSLQNGPGNDEEAGFAVDASK 347
            V+  E+AQ++     D  + AI  + +                            VDA+K
Sbjct: 671  VITREQAQEKFAQDRDPRIIAIAAHLF----------------------------VDATK 702

Query: 346  MGNFAKFINHSCTPN----LYAQNALYDHDDKSAPHIMFFACENIPPGQELVYHYNYAID 179
              N A+FI HSC PN    +++ N  Y            FA  ++ P  E+    +  + 
Sbjct: 703  RSNIARFIKHSCKPNSRLEVWSVNGFY--------RAGVFALSDLNPNAEITVDKSDLLP 754

Query: 178  QVYDENGNIKKKKCLCGSTEC 116
              +D         C CG+TEC
Sbjct: 755  --FD-------MACNCGATEC 766



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>SETD8_DROME (Q9VFK6) Histone-lysine N-methyltransferase, H4 lysine-20 specific|
           (EC 2.1.1.43) (Histone H4-K20 methyltransferase)
           (H4-K20-HMTase) (dSET8)
          Length = 691

 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 40/145 (27%), Positives = 59/145 (40%), Gaps = 6/145 (4%)
 Frame = -1

Query: 610 LQVFKTKSMGWGVKTLDYIPSGSFVCEYIGEVLDDEEAQKRMTDEYLFAIGHN-----YY 446
           LQV      G GV          FV EY+G+++   EA +R   E  +A+  N     YY
Sbjct: 557 LQVRHFMGKGRGVVADRPFKRNEFVVEYVGDLISIGEAAER---EKRYALDENAGCYMYY 613

Query: 445 DETLWEGLSRSIPSLQNGPGNDEEAGFAVDAS-KMGNFAKFINHSCTPNLYAQNALYDHD 269
            +                    +   + +DA+   G   + INHS   NL  +  L    
Sbjct: 614 FK-------------------HKSQQYCIDATVDTGKLGRLINHSRAGNLMTKVVLI--- 651

Query: 268 DKSAPHIMFFACENIPPGQELVYHY 194
            K  PH++  A ++I PG+EL Y Y
Sbjct: 652 -KQRPHLVLLAKDDIEPGEELTYDY 675



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>SETD8_BOVIN (Q2YDJ8) Histone-lysine N-methyltransferase, H4 lysine-20 specific|
           (EC 2.1.1.43) (Histone H4-K20 methyltransferase)
           (H4-K20-HMTase) (SET domain containing lysine
           methyltransferase 8) (SET domain-containing protein 8)
          Length = 352

 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 41/136 (30%), Positives = 63/136 (46%), Gaps = 6/136 (4%)
 Frame = -1

Query: 583 GWGVKTLDYIPSGSFVCEYIGEVLDDEEAQKRMTDEYLFAIG-----HNYYDETLWEGLS 419
           G GV        G FV EY G++++  +A+KR   E L+A       + YY    ++ LS
Sbjct: 227 GRGVIATKQFSRGEFVVEYHGDLIEITDAKKR---EALYAQDPSTGCYMYY----FQYLS 279

Query: 418 RSIPSLQNGPGNDEEAGFAVDASKMGN-FAKFINHSCTPNLYAQNALYDHDDKSAPHIMF 242
           ++               + VDA++  N   + INHS   N   Q  L+D D    PH++ 
Sbjct: 280 KT---------------YCVDATRETNRLGRLINHSKCGN--CQTKLHDID--GVPHLIL 320

Query: 241 FACENIPPGQELVYHY 194
            A  +I  G+EL+Y Y
Sbjct: 321 IASRDIEAGEELLYDY 336



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>SETD8_HUMAN (Q9NQR1) Histone-lysine N-methyltransferase, H4 lysine-20 specific|
           (EC 2.1.1.43) (Histone H4-K20 methyltransferase)
           (H4-K20-HMTase) (SET domain containing lysine
           methyltransferase 8) (SET domain-containing protein 8)
           (PR/SET domain-containing
          Length = 393

 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 41/136 (30%), Positives = 63/136 (46%), Gaps = 6/136 (4%)
 Frame = -1

Query: 583 GWGVKTLDYIPSGSFVCEYIGEVLDDEEAQKRMTDEYLFAIG-----HNYYDETLWEGLS 419
           G GV        G FV EY G++++  +A+KR   E L+A       + YY    ++ LS
Sbjct: 268 GRGVIATKQFSRGDFVVEYHGDLIEITDAKKR---EALYAQDPSTGCYMYY----FQYLS 320

Query: 418 RSIPSLQNGPGNDEEAGFAVDASKMGN-FAKFINHSCTPNLYAQNALYDHDDKSAPHIMF 242
           ++               + VDA++  N   + INHS   N   Q  L+D D    PH++ 
Sbjct: 321 KT---------------YCVDATRETNRLGRLINHSKCGN--CQTKLHDID--GVPHLIL 361

Query: 241 FACENIPPGQELVYHY 194
            A  +I  G+EL+Y Y
Sbjct: 362 IASRDIAAGEELLYDY 377



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>SETD8_MOUSE (Q2YDW7) Histone-lysine N-methyltransferase, H4 lysine-20 specific|
           (EC 2.1.1.43) (Histone H4-K20 methyltransferase)
           (H4-K20-HMTase) (SET domain containing lysine
           methyltransferase 8) (SET domain-containing protein 8)
          Length = 349

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 42/156 (26%), Positives = 70/156 (44%), Gaps = 6/156 (3%)
 Frame = -1

Query: 643 NRVGQKGIKFRLQVFKTKSMGWGVKTLDYIPSGSFVCEYIGEVLDDEEAQKRMTDEYLFA 464
           N + + G +  +++      G GV        G FV EY G++++  +A+KR   E L+ 
Sbjct: 204 NELIESGKEEGMKIDLIDGKGRGVIATKQFSRGDFVVEYHGDLIEITDAKKR---EALYV 260

Query: 463 IG-----HNYYDETLWEGLSRSIPSLQNGPGNDEEAGFAVDASKMGN-FAKFINHSCTPN 302
                  + YY    ++ LS++               + VDA++  N   + INHS   N
Sbjct: 261 QDPSTGCYMYY----FQYLSKT---------------YCVDATQETNRLGRLINHSKCGN 301

Query: 301 LYAQNALYDHDDKSAPHIMFFACENIPPGQELVYHY 194
              Q  L+D D    PH++  A  +I  G+EL+Y Y
Sbjct: 302 --CQTKLHDID--GVPHLILIASRDIAAGEELLYDY 333



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>YL222_MIMIV (Q5UQB9) Hypothetical SET domain-containing protein L222|
          Length = 314

 Score = 38.1 bits (87), Expect = 0.028
 Identities = 34/125 (27%), Positives = 57/125 (45%), Gaps = 5/125 (4%)
 Frame = -1

Query: 481 DEYLFAIGHNYYDE-TLWEGLSRSIPSLQNGPGNDEEAGFAVDASKMGNFA-KFINHSCT 308
           +EYLF + H   D+ +     +R + +++    N     F +D +K+   A + INHSCT
Sbjct: 77  NEYLFDMSHPRTDKFSECSEENRRLQAIKKLSSNC----FGIDGNKLLTCAIQKINHSCT 132

Query: 307 PNLYAQNALYDHDDKSAPHIMF---FACENIPPGQELVYHYNYAIDQVYDENGNIKKKKC 137
           PN      + +  +    HI+F   F+  NIP   E+   Y           G+ +  +C
Sbjct: 133 PNCAVN--ISEKYNFGGTHIVFMELFSINNIPANTEITISYG-------PVTGHKRDFEC 183

Query: 136 LCGST 122
           LCG +
Sbjct: 184 LCGKS 188



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>SET1_CAEEL (Q22795) Protein set-1|
          Length = 242

 Score = 37.7 bits (86), Expect = 0.037
 Identities = 40/153 (26%), Positives = 61/153 (39%), Gaps = 14/153 (9%)
 Frame = -1

Query: 610 LQVFKTKSMGWGVKTLDYIPSGSFVCEYIGEVLDDEEAQKRMTDEYLFAIGHNYYDETLW 431
           L+V+K    G G++T      G FV EY G +++  EA K + ++Y              
Sbjct: 106 LEVYKDVVKGRGIRTKVNFEKGDFVVEYRGVMMEYSEA-KVIEEQY-------------- 150

Query: 430 EGLSRSIPSLQNGPGNDEEAG------------FAVDASKMGNF-AKFINHS-CTPNLYA 293
                          NDEE G            + +DA+K   +  + INHS   PNL  
Sbjct: 151 --------------SNDEEIGSYMYFFEHNNKKWCIDATKESPWKGRLINHSVLRPNLKT 196

Query: 292 QNALYDHDDKSAPHIMFFACENIPPGQELVYHY 194
           +    D     + H++  A   I  G+EL+Y Y
Sbjct: 197 KVVEID----GSHHLILVARRQIAQGEELLYDY 225



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>ATX3_ARATH (Q9M364) Histone-lysine N-methyltransferase ATX3 (EC 2.1.1.43)|
            (Trithorax-homolog protein 3) (TRX-homolog protein 3)
            (Protein SET DOMAIN GROUP 14)
          Length = 902

 Score = 35.0 bits (79), Expect = 0.24
 Identities = 20/66 (30%), Positives = 30/66 (45%)
 Frame = -1

Query: 313  CTPNLYAQNALYDHDDKSAPHIMFFACENIPPGQELVYHYNYAIDQVYDENGNIKKKKCL 134
            C PN YA+  +    D     I+  A  N+  G+EL Y Y + +D+  +      K  CL
Sbjct: 839  CMPNCYAR--IVSMGDGEDNRIVLIAKTNVAAGEELTYDYLFEVDESEE-----IKVPCL 891

Query: 133  CGSTEC 116
            C +  C
Sbjct: 892  CKAPNC 897



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>ATXR3_ARATH (O23372) Probable histone-lysine N-methyltransferase ATXR3 (EC|
            2.1.1.43) (Trithorax-related protein 3) (TRX-related
            protein 3) (Protein SET DOMAIN GROUP 2)
          Length = 2351

 Score = 33.9 bits (76), Expect = 0.53
 Identities = 20/57 (35%), Positives = 27/57 (47%)
 Frame = -1

Query: 361  VDASKMGNFAKFINHSCTPNLYAQNALYDHDDKSAPHIMFFACENIPPGQELVYHYN 191
            VDA  M N+A  I HSC PN  A+    D        I  ++   I  G+E+ + YN
Sbjct: 1819 VDAMHMANYASRICHSCRPNCEAKVTAVD----GHYQIGIYSVRAIEYGEEITFDYN 1871



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>EFG1_BURPS (Q63WJ7) Elongation factor G 1 (EF-G 1)|
          Length = 704

 Score = 31.2 bits (69), Expect = 3.4
 Identities = 18/65 (27%), Positives = 31/65 (47%)
 Frame = -1

Query: 658 PPTCHNRVGQKGIKFRLQVFKTKSMGWGVKTLDYIPSGSFVCEYIGEVLDDEEAQKRMTD 479
           P  C +    KG++  L              +DY+PS + V   +G  LDD+EA++  +D
Sbjct: 264 PMLCGSAFKNKGVQAMLDA-----------VIDYLPSPADVPAILGHDLDDKEAERHPSD 312

Query: 478 EYLFA 464
           +  F+
Sbjct: 313 DEPFS 317



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>EFG1_BURP1 (Q3JV86) Elongation factor G 1 (EF-G 1)|
          Length = 704

 Score = 31.2 bits (69), Expect = 3.4
 Identities = 18/65 (27%), Positives = 31/65 (47%)
 Frame = -1

Query: 658 PPTCHNRVGQKGIKFRLQVFKTKSMGWGVKTLDYIPSGSFVCEYIGEVLDDEEAQKRMTD 479
           P  C +    KG++  L              +DY+PS + V   +G  LDD+EA++  +D
Sbjct: 264 PMLCGSAFKNKGVQAMLDA-----------VIDYLPSPADVPAILGHDLDDKEAERHPSD 312

Query: 478 EYLFA 464
           +  F+
Sbjct: 313 DEPFS 317



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>EFG1_BURMA (Q62HK4) Elongation factor G 1 (EF-G 1)|
          Length = 704

 Score = 31.2 bits (69), Expect = 3.4
 Identities = 18/65 (27%), Positives = 31/65 (47%)
 Frame = -1

Query: 658 PPTCHNRVGQKGIKFRLQVFKTKSMGWGVKTLDYIPSGSFVCEYIGEVLDDEEAQKRMTD 479
           P  C +    KG++  L              +DY+PS + V   +G  LDD+EA++  +D
Sbjct: 264 PMLCGSAFKNKGVQAMLDA-----------VIDYLPSPADVPAILGHDLDDKEAERHPSD 312

Query: 478 EYLFA 464
           +  F+
Sbjct: 313 DEPFS 317



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>BGAL_BACST (P19668) Beta-galactosidase 1 (EC 3.2.1.23) (Beta-galactosidase I)|
           (Lactase)
          Length = 672

 Score = 30.4 bits (67), Expect = 5.8
 Identities = 16/31 (51%), Positives = 20/31 (64%), Gaps = 2/31 (6%)
 Frame = -1

Query: 520 EVLDDEEAQKRMTDE--YLFAIGHNYYDETL 434
           EV ++ E Q+R TDE  YL  I HN Y+ TL
Sbjct: 601 EVAENVEVQQRETDEWKYLIIINHNDYEVTL 631



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>PRDM4_MOUSE (Q80V63) PR domain zinc finger protein 4 (PR domain-containing|
           protein 4)
          Length = 803

 Score = 30.0 bits (66), Expect = 7.6
 Identities = 21/60 (35%), Positives = 30/60 (50%), Gaps = 2/60 (3%)
 Frame = -1

Query: 280 YDHDDKSAPHIMFFACENIPPGQELVYHY--NYAIDQVYDENGNIKKKKCLCGSTECDGW 107
           Y HD K    I F   ++IPP  EL+++Y  NYA      E+ ++    C CG  EC  +
Sbjct: 507 YPHDGK----IYFCTSQDIPPESELLFYYSRNYAQQIGVPEHPDV--HLCNCGK-ECSSY 559



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>Y871_RICPR (Q9ZC95) Hypothetical protein RP871|
          Length = 360

 Score = 30.0 bits (66), Expect = 7.6
 Identities = 16/64 (25%), Positives = 29/64 (45%), Gaps = 1/64 (1%)
 Frame = -1

Query: 340 NFAKFINHSCTPNLYAQNALYDHDDKSAPHIMFFACENIPP-GQELVYHYNYAIDQVYDE 164
           N   FI+   T N+     ++D+ +   P ++F     +   G   ++  N  + Q YD 
Sbjct: 155 NITVFIDKKLTGNIMNGIIIFDNRNADNPSVVFAGSGTLNIYGNNPIFELNKGLRQEYDA 214

Query: 163 NGNI 152
           NGN+
Sbjct: 215 NGNL 218



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>YL678_MIMIV (Q5UNT8) Hypothetical SET domain protein L678|
          Length = 255

 Score = 30.0 bits (66), Expect = 7.6
 Identities = 18/49 (36%), Positives = 27/49 (55%)
 Frame = -1

Query: 340 NFAKFINHSCTPNLYAQNALYDHDDKSAPHIMFFACENIPPGQELVYHY 194
           N AKF NHSC PN+     ++  D+    ++ F+   NI  G+EL  +Y
Sbjct: 136 NGAKF-NHSCVPNV-----IFVSDEN---YMYFYTVRNIKTGEELTDNY 175



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>RM18_MOUSE (Q9CQL5) 39S ribosomal protein L18, mitochondrial precursor (L18mt)|
           (MRP-L18)
          Length = 180

 Score = 30.0 bits (66), Expect = 7.6
 Identities = 23/70 (32%), Positives = 28/70 (40%)
 Frame = -1

Query: 604 VFKTKSMGWGVKTLDYIPSGSFVCEYIGEVLDDEEAQKRMTDEYLFAIGHNYYDETLWEG 425
           V    +  W +K   Y       CE IG VL    AQ+ +     F +    Y  T WE 
Sbjct: 102 VVSASTREWAIKKHLYSTRNVVACESIGRVL----AQRCLEAGINFMV----YQPTPWEA 153

Query: 424 LSRSIPSLQN 395
            S SI  LQN
Sbjct: 154 SSDSIKRLQN 163



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>FDXG_HAEIN (P46448) Formate dehydrogenase major subunit (EC 1.2.1.2) (Formate|
           dehydrogenase alpha subunit) (FDH alpha subunit)
          Length = 1028

 Score = 29.6 bits (65), Expect = 10.0
 Identities = 19/58 (32%), Positives = 26/58 (44%), Gaps = 11/58 (18%)
 Frame = -1

Query: 241 FACENIPPGQELVYHYN-YAIDQVYDENGNIKKKKCLC----------GSTECDGWLY 101
           +A  + P   EL    N YA++ +YD NGN+  KK             G+T    WLY
Sbjct: 689 YAQPHSPSAVELAKELNGYALEDLYDPNGNLMYKKGQLLNGFAHLRDDGTTTSGNWLY 746


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 108,315,108
Number of Sequences: 219361
Number of extensions: 2305887
Number of successful extensions: 5890
Number of sequences better than 10.0: 85
Number of HSP's better than 10.0 without gapping: 5501
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5770
length of database: 80,573,946
effective HSP length: 109
effective length of database: 56,663,597
effective search space used: 7536258401
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
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