>ACSL1_HUMAN (P33121) Long-chain-fatty-acid--CoA ligase 1 (EC 6.2.1.3)|
           (Long-chain acyl-CoA synthetase 1) (LACS 1)
           (Palmitoyl-CoA ligase 1) (Long-chain fatty acid CoA
           ligase 2) (Long-chain acyl-CoA synthetase 2) (LACS 2)
           (Acyl-CoA synthetase 1) (ACS1) (Pa
          Length = 698

 Score =  131 bits (330), Expect = 2e-30
 Identities = 67/145 (46%), Positives = 94/145 (64%)
 Frame = -1

Query: 729 IDRKKNIFKLAQGEYIAPEKIENVYAKCKFIAQCFVYGDSFNSCXXXXXXXXXXXLKSWA 550
           IDRKK+IFKLAQGEYIAPEKIEN+Y + + +AQ FV+G+S  +            L SWA
Sbjct: 553 IDRKKHIFKLAQGEYIAPEKIENIYMRSEPVAQVFVHGESLQAFLIAIVVPDVETLCSWA 612

Query: 549 ALEGIQYEDLRQLCSDPRARAAVLADMDSIGKEAQLRGFEFVKAVTLVAESFTLENGLLT 370
              G +     +LC +   + A+L DM  +GK++ L+ FE VK +TL  E F+++NGLLT
Sbjct: 613 QKRGFE-GSFEELCRNKDVKKAILEDMVRLGKDSGLKPFEQVKGITLHPELFSIDNGLLT 671

Query: 369 PTFKVKRPQAKAYFAKEITDMYAQL 295
           PT K KRP+ + YF  +I D+Y+ +
Sbjct: 672 PTMKAKRPELRNYFRSQIDDLYSTI 696

>ACSL1_MOUSE (P41216) Long-chain-fatty-acid--CoA ligase 1 (EC 6.2.1.3)|
           (Long-chain acyl-CoA synthetase 1) (LACS 1)
          Length = 699

 Score =  131 bits (329), Expect = 2e-30
 Identities = 67/145 (46%), Positives = 93/145 (64%)
 Frame = -1

Query: 729 IDRKKNIFKLAQGEYIAPEKIENVYAKCKFIAQCFVYGDSFNSCXXXXXXXXXXXLKSWA 550
           IDRKK+IFKLAQGEYIAPEKIEN+Y + + +AQ FV+G+S  +            L SWA
Sbjct: 554 IDRKKHIFKLAQGEYIAPEKIENIYLRSEAVAQVFVHGESLQAFLIAVVVPDVESLPSWA 613

Query: 549 ALEGIQYEDLRQLCSDPRARAAVLADMDSIGKEAQLRGFEFVKAVTLVAESFTLENGLLT 370
              G+Q     +LC +     A+L D+  +GKEA L+ FE VK + +  E F+++NGLLT
Sbjct: 614 QKRGLQ-GSFEELCRNKDINKAILDDLLKLGKEAGLKPFEQVKGIAVHPELFSIDNGLLT 672

Query: 369 PTFKVKRPQAKAYFAKEITDMYAQL 295
           PT K KRP+ + YF  +I ++YA +
Sbjct: 673 PTLKAKRPELRNYFRSQIDELYATI 697

>ACSL6_HUMAN (Q9UKU0) Long-chain-fatty-acid--CoA ligase 6 (EC 6.2.1.3)|
           (Long-chain acyl-CoA synthetase 6) (LACS 6)
          Length = 697

 Score =  131 bits (329), Expect = 2e-30
 Identities = 67/145 (46%), Positives = 97/145 (66%), Gaps = 2/145 (1%)
 Frame = -1

Query: 729 IDRKKNIFKLAQGEYIAPEKIENVYAKCKFIAQCFVYGDSFNSCXXXXXXXXXXXLKSWA 550
           IDRKK+IFKLAQGEY+APEKIEN+Y + + +AQ +V+GDS  +            + SWA
Sbjct: 553 IDRKKHIFKLAQGEYVAPEKIENIYIRSQPVAQIYVHGDSLKAFLVGIVVPDPEVMPSWA 612

Query: 549 ALEGIQ--YEDLRQLCSDPRARAAVLADMDSIGKEAQLRGFEFVKAVTLVAESFTLENGL 376
              GI+  Y DL   C++   + A+L DM  +GKE+ L  FE VKA+ + ++ F+++NGL
Sbjct: 613 QKRGIEGTYADL---CTNKDLKKAILEDMVRLGKESGLHSFEQVKAIHIHSDMFSVQNGL 669

Query: 375 LTPTFKVKRPQAKAYFAKEITDMYA 301
           LTPT K KRP+ + YF K+I ++Y+
Sbjct: 670 LTPTLKAKRPELREYFKKQIEELYS 694

>ACSL6_RAT (P33124) Long-chain-fatty-acid--CoA ligase 6 (EC 6.2.1.3)|
           (Long-chain acyl-CoA synthetase 6) (LACS 6)
           (Long-chain-fatty-acid--CoA ligase, brain isozyme)
          Length = 697

 Score =  130 bits (327), Expect = 4e-30
 Identities = 64/143 (44%), Positives = 95/143 (66%)
 Frame = -1

Query: 729 IDRKKNIFKLAQGEYIAPEKIENVYAKCKFIAQCFVYGDSFNSCXXXXXXXXXXXLKSWA 550
           IDRKK+IFKLAQGEY+APEKIEN+Y + + +AQ +V+GDS  +            +  WA
Sbjct: 553 IDRKKHIFKLAQGEYVAPEKIENIYIRSEPVAQIYVHGDSLKAFLVGIVVPDPEVMPCWA 612

Query: 549 ALEGIQYEDLRQLCSDPRARAAVLADMDSIGKEAQLRGFEFVKAVTLVAESFTLENGLLT 370
             +GI+  + ++LC     + A+L DM  +GKE+ L  FE VKA+ +  + F+++NGLLT
Sbjct: 613 QKKGIE-GNYQELCKSKELKKAILDDMVMLGKESGLHSFEQVKAIYIHCDMFSVQNGLLT 671

Query: 369 PTFKVKRPQAKAYFAKEITDMYA 301
           PT K KRP+ + YF K+I ++Y+
Sbjct: 672 PTLKAKRPELREYFKKQIEELYS 694

>ACSL6_MOUSE (Q91WC3) Long-chain-fatty-acid--CoA ligase 6 (EC 6.2.1.3)|
           (Long-chain acyl-CoA synthetase 6) (LACS 6)
          Length = 697

 Score =  130 bits (327), Expect = 4e-30
 Identities = 65/142 (45%), Positives = 94/142 (66%)
 Frame = -1

Query: 729 IDRKKNIFKLAQGEYIAPEKIENVYAKCKFIAQCFVYGDSFNSCXXXXXXXXXXXLKSWA 550
           IDRKK+IFKLAQGEY+APEKIEN+Y + + +AQ +V+GDS  +            + SWA
Sbjct: 553 IDRKKHIFKLAQGEYVAPEKIENIYIRSEPVAQIYVHGDSLKAFLVGIVVPDPEVMPSWA 612

Query: 549 ALEGIQYEDLRQLCSDPRARAAVLADMDSIGKEAQLRGFEFVKAVTLVAESFTLENGLLT 370
             +GI+    ++LC     + A+L DM  +GKE+ L  FE VKA+ +  + F+++NGLLT
Sbjct: 613 QKKGIE-GTYQELCMKKELKKAILDDMVMLGKESGLHSFEQVKAIYIHCDMFSVQNGLLT 671

Query: 369 PTFKVKRPQAKAYFAKEITDMY 304
           PT K KRP+ + YF K+I ++Y
Sbjct: 672 PTLKAKRPELREYFKKQIEELY 693

>ACSL1_CAVPO (Q9JID6) Long-chain-fatty-acid--CoA ligase 1 (EC 6.2.1.3)|
           (Long-chain acyl-CoA synthetase 1) (LACS 1)
           (Palmitoyl-CoA ligase)
          Length = 698

 Score =  129 bits (325), Expect = 7e-30
 Identities = 65/145 (44%), Positives = 93/145 (64%)
 Frame = -1

Query: 729 IDRKKNIFKLAQGEYIAPEKIENVYAKCKFIAQCFVYGDSFNSCXXXXXXXXXXXLKSWA 550
           IDRKK+IFKLAQGEYIAPEKIEN+Y + + +AQ FV+G+S  +            L SWA
Sbjct: 553 IDRKKHIFKLAQGEYIAPEKIENIYVRSEPVAQVFVHGESLQAFLIAIVVPDAESLASWA 612

Query: 549 ALEGIQYEDLRQLCSDPRARAAVLADMDSIGKEAQLRGFEFVKAVTLVAESFTLENGLLT 370
              G +     +LC +   + A+L DM  IGK++ L+ FE V+ + L  E F+++NGLLT
Sbjct: 613 RKRGFE-GSFEELCRNKDVKKAILEDMVRIGKDSGLKSFEQVRGIALHPELFSVDNGLLT 671

Query: 369 PTFKVKRPQAKAYFAKEITDMYAQL 295
           PT K KRP+ + YF  +I ++Y+ +
Sbjct: 672 PTMKAKRPELRNYFRSQIDELYSTI 696

>ACSL5_HUMAN (Q9ULC5) Long-chain-fatty-acid--CoA ligase 5 (EC 6.2.1.3)|
           (Long-chain acyl-CoA synthetase 5) (LACS 5)
          Length = 683

 Score =  129 bits (324), Expect = 9e-30
 Identities = 70/147 (47%), Positives = 92/147 (62%)
 Frame = -1

Query: 729 IDRKKNIFKLAQGEYIAPEKIENVYAKCKFIAQCFVYGDSFNSCXXXXXXXXXXXLKSWA 550
           IDRKKNIFKLAQGEYIAPEKIEN+Y + + + Q FV+G+S  S            L S+A
Sbjct: 538 IDRKKNIFKLAQGEYIAPEKIENIYNRSQPVLQIFVHGESLRSSLVGVVVPDTDVLPSFA 597

Query: 549 ALEGIQYEDLRQLCSDPRARAAVLADMDSIGKEAQLRGFEFVKAVTLVAESFTLENGLLT 370
           A  G++     +LC +   R A+L D+  IGKE+ L+ FE VKA+ L  E F++ENGLLT
Sbjct: 598 AKLGVK-GSFEELCQNQVVREAILEDLQKIGKESGLKTFEQVKAIFLHPEPFSIENGLLT 656

Query: 369 PTFKVKRPQAKAYFAKEITDMYAQLLD 289
           PT K KR +   YF  +I  +Y  + D
Sbjct: 657 PTLKAKRGELSKYFRTQIDSLYEHIQD 683

>ACSL1_RAT (P18163) Long-chain-fatty-acid--CoA ligase 1 (EC 6.2.1.3)|
           (Long-chain acyl-CoA synthetase 1) (LACS 1)
           (Long-chain-fatty-acid--CoA ligase, liver isozyme)
          Length = 699

 Score =  129 bits (323), Expect = 1e-29
 Identities = 66/145 (45%), Positives = 91/145 (62%)
 Frame = -1

Query: 729 IDRKKNIFKLAQGEYIAPEKIENVYAKCKFIAQCFVYGDSFNSCXXXXXXXXXXXLKSWA 550
           IDRKK+IFKLAQGEYIAPEKIEN+Y + + +AQ FV+G+S  +            L SWA
Sbjct: 554 IDRKKHIFKLAQGEYIAPEKIENIYLRSEAVAQVFVHGESLQAFLIAIVVPDVEILPSWA 613

Query: 549 ALEGIQYEDLRQLCSDPRARAAVLADMDSIGKEAQLRGFEFVKAVTLVAESFTLENGLLT 370
              G Q     +LC +     A+L DM  +GK A L+ FE VK + +  E F+++NGLLT
Sbjct: 614 QKRGFQ-GSFEELCRNKDINKAILEDMVKLGKNAGLKPFEQVKGIAVHPELFSIDNGLLT 672

Query: 369 PTFKVKRPQAKAYFAKEITDMYAQL 295
           PT K KRP+ + YF  +I ++Y+ +
Sbjct: 673 PTLKAKRPELRNYFRSQIDELYSTI 697

>ACSL5_MOUSE (Q8JZR0) Long-chain-fatty-acid--CoA ligase 5 (EC 6.2.1.3)|
           (Long-chain acyl-CoA synthetase 5) (LACS 5)
          Length = 683

 Score =  125 bits (313), Expect = 2e-28
 Identities = 66/145 (45%), Positives = 91/145 (62%)
 Frame = -1

Query: 729 IDRKKNIFKLAQGEYIAPEKIENVYAKCKFIAQCFVYGDSFNSCXXXXXXXXXXXLKSWA 550
           +DRKKNIFKLAQGEYIAPEKIENVY++ + + Q FV+G+S  S            L S+A
Sbjct: 538 VDRKKNIFKLAQGEYIAPEKIENVYSRSRPVLQVFVHGESLRSFLIGVVVPDPDSLPSFA 597

Query: 549 ALEGIQYEDLRQLCSDPRARAAVLADMDSIGKEAQLRGFEFVKAVTLVAESFTLENGLLT 370
           A  G++     +LC +   + A+L D+  IGKE  L+ FE VK++ +  E FT+ENGLLT
Sbjct: 598 AKIGVK-GSFEELCKNQCVKEAILEDLQKIGKEGGLKSFEQVKSIFVHPEPFTIENGLLT 656

Query: 369 PTFKVKRPQAKAYFAKEITDMYAQL 295
           PT K KR +   +F  +I  +Y  +
Sbjct: 657 PTLKAKRVELAKFFQTQIKSLYESI 681

>ACSL5_RAT (O88813) Long-chain-fatty-acid--CoA ligase 5 (EC 6.2.1.3)|
           (Long-chain acyl-CoA synthetase 5) (LACS 5)
          Length = 683

 Score =  124 bits (310), Expect = 4e-28
 Identities = 66/145 (45%), Positives = 91/145 (62%)
 Frame = -1

Query: 729 IDRKKNIFKLAQGEYIAPEKIENVYAKCKFIAQCFVYGDSFNSCXXXXXXXXXXXLKSWA 550
           IDRKKNIFKLAQGEYIAPEKIENVY++ + I Q FV+G+S  S            L S+A
Sbjct: 538 IDRKKNIFKLAQGEYIAPEKIENVYSRSRPILQVFVHGESLRSFLIGVVVPDPESLPSFA 597

Query: 549 ALEGIQYEDLRQLCSDPRARAAVLADMDSIGKEAQLRGFEFVKAVTLVAESFTLENGLLT 370
           A  G++     +LC +   + A+L D+  +GKE  L+ FE VK++ +  E F++ENGLLT
Sbjct: 598 AKIGVK-GSFEELCQNQCVKKAILEDLQKVGKEGGLKSFEQVKSIFVHPEPFSIENGLLT 656

Query: 369 PTFKVKRPQAKAYFAKEITDMYAQL 295
           PT K KR +   +F  +I  +Y  +
Sbjct: 657 PTLKAKRVELAKFFQTQIKSLYESI 681

>LCF2_YEAST (P39518) Long-chain-fatty-acid--CoA ligase 2 (EC 6.2.1.3) (Long-chain|
            acyl-CoA synthetase 2) (Fatty acid activator 2)
          Length = 744

 Score = 82.0 bits (201), Expect = 2e-15
 Identities = 51/151 (33%), Positives = 78/151 (51%), Gaps = 7/151 (4%)
 Frame = -1

Query: 729  IDRKKNIFKLAQGEYIAPEKIENVY-AKCKFIAQCFVYGDSFNSCXXXXXXXXXXXLKSW 553
            IDR KN FKLA GEYIAPEKIEN+Y + C +I Q FV+GD   +             +  
Sbjct: 587  IDRVKNFFKLAHGEYIAPEKIENIYLSSCPYITQIFVFGDPLKTFLVGIVGVDVDAAQPI 646

Query: 552  AALEGIQYED------LRQLCSDPRARAAVLADMDSIGKEAQLRGFEFVKAVTLVAESFT 391
             A +  + +       +  L  + + R   L  ++       L+GFE +  + +  E  T
Sbjct: 647  LAAKHPEVKTWTKEVLVENLNRNKKLRKEFLNKINKC--TDGLQGFEKLHNIKVGLEPLT 704

Query: 390  LENGLLTPTFKVKRPQAKAYFAKEITDMYAQ 298
            LE+ ++TPTFK+KR +A  +F   +  +YA+
Sbjct: 705  LEDDVVTPTFKIKRAKASKFFKDTLDQLYAE 735

>LCF1_SCHPO (O60135) Long-chain-fatty-acid--CoA ligase 1 (EC 6.2.1.3)|
           (Long-chain acyl-CoA synthetase 1) (Fatty acid activator
           1)
          Length = 676

 Score = 69.3 bits (168), Expect = 1e-11
 Identities = 46/146 (31%), Positives = 67/146 (45%), Gaps = 2/146 (1%)
 Frame = -1

Query: 729 IDRKKNIFKLAQGEYIAPEKIENVYAKCKFIAQCFVYGDSFNSCXXXXXXXXXXXLKSWA 550
           IDRKKN+ K   GEYIA EK+E+ Y     ++   VY D                ++  A
Sbjct: 531 IDRKKNLVKTQNGEYIALEKLESRYRTSSLVSNICVYADQTKVKPLAIIVPNEPVVRKLA 590

Query: 549 ALEGIQYEDL--RQLCSDPRARAAVLADMDSIGKEAQLRGFEFVKAVTLVAESFTLENGL 376
             +     D    ++C + + R  V  D+  IG+       E ++ V LV   FT ENGL
Sbjct: 591 TEQAGLSPDASWEEVCHNKKVRQLVYDDLIRIGRSHHFANIELIQNVVLVPIEFTPENGL 650

Query: 375 LTPTFKVKRPQAKAYFAKEITDMYAQ 298
           +T   K++R +    F KEI   YA+
Sbjct: 651 VTAAQKLQRRKILDRFKKEIDAAYAE 676

>LCF4_YEAST (P47912) Long-chain-fatty-acid--CoA ligase 4 (EC 6.2.1.3)|
           (Long-chain acyl-CoA synthetase 4) (Fatty acid activator
           4)
          Length = 694

 Score = 68.6 bits (166), Expect = 2e-11
 Identities = 48/147 (32%), Positives = 68/147 (46%), Gaps = 3/147 (2%)
 Frame = -1

Query: 729 IDRKKNIFKLAQGEYIAPEKIENVYAKCKFIAQCFVYGDSFNSCXXXXXXXXXXXLKSWA 550
           IDRKKN+ K   GEYIA EK+E++Y    ++    VY D  N               S  
Sbjct: 547 IDRKKNLVKTLNGEYIALEKLESIYRSNPYVQNICVYADE-NKVKPVGIVVPNLGHLSKL 605

Query: 549 ALE-GIQY--EDLRQLCSDPRARAAVLADMDSIGKEAQLRGFEFVKAVTLVAESFTLENG 379
           A+E GI    ED+     + + + AV  DM S  K   L G E +  +    E +T ENG
Sbjct: 606 AIELGIMVPGEDVESYIHEKKLQDAVCKDMLSTAKSQGLNGIELLCGIVFFEEEWTPENG 665

Query: 378 LLTPTFKVKRPQAKAYFAKEITDMYAQ 298
           L+T   K+KR    A    ++  +Y +
Sbjct: 666 LVTSAQKLKRRDILAAVKPDVERVYKE 692

>ACSL4_RAT (O35547) Long-chain-fatty-acid--CoA ligase 4 (EC 6.2.1.3)|
           (Long-chain acyl-CoA synthetase 4) (LACS 4)
          Length = 670

 Score = 67.4 bits (163), Expect = 4e-11
 Identities = 43/142 (30%), Positives = 67/142 (47%)
 Frame = -1

Query: 729 IDRKKNIFKLAQGEYIAPEKIENVYAKCKFIAQCFVYGDSFNSCXXXXXXXXXXXLKSWA 550
           IDRKK++ KL  GEY++  K+E     C  I     +  S  S            L   A
Sbjct: 527 IDRKKDLVKLQAGEYVSLGKVEAALKNCPLIDNICAFAKSDQSYVISFVVPNQKKLTLLA 586

Query: 549 ALEGIQYEDLRQLCSDPRARAAVLADMDSIGKEAQLRGFEFVKAVTLVAESFTLENGLLT 370
             +G++   +  +C++P   A +L ++       +L  FE    V L  E +T E GL+T
Sbjct: 587 QQKGVEGSWV-DICNNPAMEAEILKEIREAANAMKLERFEIPIKVRLSPEPWTPETGLVT 645

Query: 369 PTFKVKRPQAKAYFAKEITDMY 304
             FK+KR + K ++ K+I  MY
Sbjct: 646 DAFKLKRKELKNHYLKDIERMY 667

>ACSL4_MOUSE (Q9QUJ7) Long-chain-fatty-acid--CoA ligase 4 (EC 6.2.1.3)|
           (Long-chain acyl-CoA synthetase 4) (LACS 4) (mACS4)
          Length = 711

 Score = 65.9 bits (159), Expect = 1e-10
 Identities = 42/142 (29%), Positives = 66/142 (46%)
 Frame = -1

Query: 729 IDRKKNIFKLAQGEYIAPEKIENVYAKCKFIAQCFVYGDSFNSCXXXXXXXXXXXLKSWA 550
           IDRKK++ KL  GEY+   K+E     C  I     +  S  S            L   A
Sbjct: 568 IDRKKDLVKLQAGEYVFLGKVEAALKNCPLIDNICAFAKSDQSYVISFVVPNQKKLTLLA 627

Query: 549 ALEGIQYEDLRQLCSDPRARAAVLADMDSIGKEAQLRGFEFVKAVTLVAESFTLENGLLT 370
             +G++   +  +C++P   A +L ++       +L  FE    V L  E +T E GL+T
Sbjct: 628 QQKGVEGSWV-DICNNPAMEAEILKEIREAANAMKLERFEIPIKVRLSPEPWTPETGLVT 686

Query: 369 PTFKVKRPQAKAYFAKEITDMY 304
             FK+KR + K ++ K++  MY
Sbjct: 687 DAFKLKRKELKNHYLKDVERMY 708

>ACSL4_HUMAN (O60488) Long-chain-fatty-acid--CoA ligase 4 (EC 6.2.1.3)|
           (Long-chain acyl-CoA synthetase 4) (LACS 4)
          Length = 711

 Score = 65.9 bits (159), Expect = 1e-10
 Identities = 42/142 (29%), Positives = 67/142 (47%)
 Frame = -1

Query: 729 IDRKKNIFKLAQGEYIAPEKIENVYAKCKFIAQCFVYGDSFNSCXXXXXXXXXXXLKSWA 550
           IDRKK++ KL  GEY++  K+E     C  I     +  S  S            L   A
Sbjct: 568 IDRKKDLVKLQAGEYVSLGKVEAALKNCPLIDNICAFAKSDQSYVISFVVPNQKRLTLLA 627

Query: 549 ALEGIQYEDLRQLCSDPRARAAVLADMDSIGKEAQLRGFEFVKAVTLVAESFTLENGLLT 370
             +G++   +  +C++P   A +L ++       +L  FE    V L  E +T E GL+T
Sbjct: 628 QQKGVEGTWV-DICNNPAMEAEILKEIREAANAMKLERFEIPIKVRLSPEPWTPETGLVT 686

Query: 369 PTFKVKRPQAKAYFAKEITDMY 304
             FK+KR + + ++ K+I  MY
Sbjct: 687 DAFKLKRKELRNHYLKDIERMY 708

>LCF3_YEAST (P39002) Long-chain-fatty-acid--CoA ligase 3 (EC 6.2.1.3)|
           (Long-chain acyl-CoA synthetase 3) (Fatty acid activator
           3)
          Length = 694

 Score = 64.7 bits (156), Expect = 3e-10
 Identities = 45/146 (30%), Positives = 65/146 (44%), Gaps = 2/146 (1%)
 Frame = -1

Query: 729 IDRKKNIFKLAQGEYIAPEKIENVYAKCKFIAQCFVYGDSFNSCXXXXXXXXXXXLKSWA 550
           IDR+KN+ K   GEYIA EK+E+VY    ++    VY D                L  +A
Sbjct: 547 IDRRKNLVKTLNGEYIALEKLESVYRSNSYVKNICVYADESRVKPVGIVVPNPGPLSKFA 606

Query: 549 ALEGI--QYEDLRQLCSDPRARAAVLADMDSIGKEAQLRGFEFVKAVTLVAESFTLENGL 376
               I  + ED+     D   R AV  +M +  K   L G E +  +    E +T ENG 
Sbjct: 607 VKLRIMKKGEDIENYIHDKALRNAVFKEMIATAKSQGLVGIELLCGIVFFDEEWTPENGF 666

Query: 375 LTPTFKVKRPQAKAYFAKEITDMYAQ 298
           +T   K+KR +  A    E+  +Y +
Sbjct: 667 VTSAQKLKRREILAAVKSEVERVYKE 692

>ACSL3_HUMAN (O95573) Long-chain-fatty-acid--CoA ligase 3 (EC 6.2.1.3) (Long-chain|
            acyl-CoA synthetase 3) (LACS 3)
          Length = 720

 Score = 62.8 bits (151), Expect = 1e-09
 Identities = 41/144 (28%), Positives = 65/144 (45%)
 Frame = -1

Query: 729  IDRKKNIFKLAQGEYIAPEKIENVYAKCKFIAQCFVYGDSFNSCXXXXXXXXXXXLKSWA 550
            IDRKK++ KL  GEY++  K+E        +     Y +S++S            L   A
Sbjct: 577  IDRKKDLVKLQAGEYVSLGKVEAALKNLPLVDNICAYANSYHSYVIGFVVPNQKELTELA 636

Query: 549  ALEGIQYEDLRQLCSDPRARAAVLADMDSIGKEAQLRGFEFVKAVTLVAESFTLENGLLT 370
              +G++     +LC+       VL  +      A L  FE    + L  E +T E GL+T
Sbjct: 637  RKKGLK-GTWEELCNSCEMENEVLKVLSEAAISASLEKFEIPVKIRLSPEPWTPETGLVT 695

Query: 369  PTFKVKRPQAKAYFAKEITDMYAQ 298
              FK+KR + K ++  +I  MY +
Sbjct: 696  DAFKLKRKELKTHYQADIERMYGR 719

>ACSL3_MOUSE (Q9CZW4) Long-chain-fatty-acid--CoA ligase 3 (EC 6.2.1.3) (Long-chain|
            acyl-CoA synthetase 3) (LACS 3)
          Length = 720

 Score = 62.4 bits (150), Expect = 1e-09
 Identities = 41/144 (28%), Positives = 64/144 (44%)
 Frame = -1

Query: 729  IDRKKNIFKLAQGEYIAPEKIENVYAKCKFIAQCFVYGDSFNSCXXXXXXXXXXXLKSWA 550
            IDRKK++ KL  GEY++  K+E        I     Y +S++S            L   A
Sbjct: 577  IDRKKDLVKLQAGEYVSLGKVEAALKNLPLIDNICAYANSYHSYVIGFVVPNQKELTELA 636

Query: 549  ALEGIQYEDLRQLCSDPRARAAVLADMDSIGKEAQLRGFEFVKAVTLVAESFTLENGLLT 370
              +G +     +LC+       VL  +      A L  FE    + L  + +T E GL+T
Sbjct: 637  RTKGFK-GTWEELCNSSEMENEVLKVLSEAAISASLEKFEIPLKIRLSPDPWTPETGLVT 695

Query: 369  PTFKVKRPQAKAYFAKEITDMYAQ 298
              FK+KR + K ++  +I  MY +
Sbjct: 696  DAFKLKRKELKTHYQADIERMYGR 719

>LCFH_HAEIN (P44446) Putative long-chain-fatty-acid--CoA ligase (EC 6.2.1.3)|
           (Long-chain acyl-CoA synthetase) (LACS)
          Length = 607

 Score = 62.0 bits (149), Expect = 2e-09
 Identities = 43/141 (30%), Positives = 71/141 (50%)
 Frame = -1

Query: 726 DRKKNIFKLAQGEYIAPEKIENVYAKCKFIAQCFVYGDSFNSCXXXXXXXXXXXLKSWAA 547
           DR K + K + G+YIAP+ IE+   K KFI Q  +  D+               L+ +A 
Sbjct: 465 DRIKELMKTSNGKYIAPQYIESKIGKDKFIEQIAIIADA-KKYVSALIVPCFDSLEEYAK 523

Query: 546 LEGIQYEDLRQLCSDPRARAAVLADMDSIGKEAQLRGFEFVKAVTLVAESFTLENGLLTP 367
              I+Y D  +L  +          ++++ KE  L  FE VK  TL++++F+++ G +TP
Sbjct: 524 QLNIKYHDRLELLKNSDILKMFEHRINAVQKE--LAHFEQVKKFTLLSQAFSIKLGEITP 581

Query: 366 TFKVKRPQAKAYFAKEITDMY 304
           T K++R      + K+I  MY
Sbjct: 582 TLKLRRKVILERYRKQIEAMY 602

>ACSL3_RAT (Q63151) Long-chain-fatty-acid--CoA ligase 3 (EC 6.2.1.3) (Long-chain|
            acyl-CoA synthetase 3) (LACS 3) (Brain acyl-CoA synthtase
            II)
          Length = 720

 Score = 62.0 bits (149), Expect = 2e-09
 Identities = 41/144 (28%), Positives = 63/144 (43%)
 Frame = -1

Query: 729  IDRKKNIFKLAQGEYIAPEKIENVYAKCKFIAQCFVYGDSFNSCXXXXXXXXXXXLKSWA 550
            IDRKK++ KL  GEY++  K+E        I     Y +S++S            L   A
Sbjct: 577  IDRKKDLVKLQAGEYVSLGKVEAALKNLPLIDNICAYANSYHSYVIGFVVPNQKELTELA 636

Query: 549  ALEGIQYEDLRQLCSDPRARAAVLADMDSIGKEAQLRGFEFVKAVTLVAESFTLENGLLT 370
              +G       +LC+       VL  +      A L  FE    + L  + +T E GL+T
Sbjct: 637  RTKGFN-GTWEELCNSSEMENEVLKVLSEAAISASLEKFEIPLKIRLSPDPWTPETGLVT 695

Query: 369  PTFKVKRPQAKAYFAKEITDMYAQ 298
              FK+KR + K ++  +I  MY +
Sbjct: 696  DAFKLKRKELKTHYQADIERMYGR 719

>LCF1_YEAST (P30624) Long-chain-fatty-acid--CoA ligase 1 (EC 6.2.1.3)|
           (Long-chain acyl-CoA synthetase 1) (Fatty acid activator
           1)
          Length = 700

 Score = 61.6 bits (148), Expect = 2e-09
 Identities = 41/132 (31%), Positives = 61/132 (46%), Gaps = 5/132 (3%)
 Frame = -1

Query: 729 IDRKKNIFKLAQGEYIAPEKIENVYAKCKFIAQCFVYGDSFNSCXXXXXXXXXXXLKSWA 550
           IDRKKN+ K   GEYIA EK+E+VY   +++A   VY D   +            L   A
Sbjct: 551 IDRKKNLVKTMNGEYIALEKLESVYRSNEYVANICVYADQSKTKPVGIIVPNHAPLTKLA 610

Query: 549 ALEGIQYE-----DLRQLCSDPRARAAVLADMDSIGKEAQLRGFEFVKAVTLVAESFTLE 385
              GI  +     ++     D +   AV +D+   GK+  L G E +  +      +T +
Sbjct: 611 KKLGIMEQKDSSINIENYLEDAKLIKAVYSDLLKTGKDQGLVGIELLAGIVFFDGEWTPQ 670

Query: 384 NGLLTPTFKVKR 349
           NG +T   K+KR
Sbjct: 671 NGFVTSAQKLKR 682

>ORA_PLAFN (P16405) Octapeptide-repeat antigen (ORA) (Fragment)|
          Length = 701

 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 42/166 (25%), Positives = 70/166 (42%), Gaps = 16/166 (9%)
 Frame = -1

Query: 729 IDRKKNIFKLAQGEYIAPEKIENVYAKCKFIAQCFVYGDSFNSCXXXXXXXXXXXLKSWA 550
           +DR K + KL+QGEYI  E I N+Y++  F+  C  YGD  +S             K + 
Sbjct: 483 LDRSKGLVKLSQGEYIETEMINNLYSQIPFVNFCVAYGD--DSMDGPLGIISVDKHKLFT 540

Query: 549 ALE--------GIQYEDLRQLCSDPRARAAVLAD-----MDSIGKEAQLRGFEFVKAVTL 409
            L+        G+  ++  +   D      +  D     M  I K+  L  +  +  + L
Sbjct: 541 FLKNDNMLKTTGVDEKNFSEKLIDETLNDPIYVDYVKGKMMEIYKKTNLNRYNVINDIYL 600

Query: 408 VAESFTLENGLLTPTFKVKRPQA---KAYFAKEITDMYAQLLDAES 280
            ++ +   N  LTPT K++R       ++F  E+   Y + L   S
Sbjct: 601 TSKPWDTTN-YLTPTLKIRRFNVFKDFSFFIDEVKKKYEEKLSGSS 645

>FAD11_MYCTU (Q10776) Putative fatty-acid--CoA ligase fadD11 (EC 6.2.1.-)|
           (Acyl-CoA synthetase)
          Length = 571

 Score = 43.1 bits (100), Expect = 9e-04
 Identities = 39/154 (25%), Positives = 65/154 (42%), Gaps = 1/154 (0%)
 Frame = -1

Query: 729 IDRKKNIFKLAQGEYIAPEKIEN-VYAKCKFIAQCFVYGDSFNSCXXXXXXXXXXXLKSW 553
           +DRKK +   A G+ ++P  IEN + A C  +      GD   +            L  +
Sbjct: 413 VDRKKELIINAAGKNMSPANIENTILAACPMVGVMMAIGDG-RTYNTALLVFDADSLGPY 471

Query: 552 AALEGIQYEDLRQLCSDPRARAAVLADMDSIGKEAQLRGFEFVKAVTLVAESFTLENGLL 373
           AA  G+       L +DP   A + A +      A+L   E +K   ++   +      +
Sbjct: 472 AAQRGLDASP-AALAADPEVIARIAAGVAE--GNAKLSRVEQIKRFRILPTLWEPGGDEI 528

Query: 372 TPTFKVKRPQAKAYFAKEITDMYAQLLDAESARP 271
           T T K+KR +  A ++ EI ++YA  L  +   P
Sbjct: 529 TLTMKLKRRRIAAKYSAEIEELYASELRPQVYEP 562

>YEN1_SCHPO (O13695) Hypothetical serine-rich protein C11G7.01 in chromosome I|
          Length = 536

 Score = 40.4 bits (93), Expect = 0.006
 Identities = 32/119 (26%), Positives = 59/119 (49%), Gaps = 2/119 (1%)
 Frame = +2

Query: 266 NLGLADSASSSCAYISVISFAKYAFACGLLTLNVGVRRPFSSV--NDSATRVTALTNSKP 439
           N    D++ SS A  S+ + +  A A   L+ +  +    SS+  + SAT +++ ++S P
Sbjct: 6   NTSSVDTSLSSSASSSIPASSSSAAASTSLSSSSVIPSSSSSMLSSSSATAISSSSSSSP 65

Query: 440 LSCASFPIESMSASTAALALGSEQSCLKSSYWIPSNAAQLFNTSGSTATTATRQELKLS 616
           LS +SF   + S+   +L   S Q    SS  + S+++    +S S + T++     LS
Sbjct: 66  LSSSSFTSPASSSFITSLVSSSSQQSSSSSASLTSSSSATLTSSSSASPTSSSSSHALS 124



 Score = 29.6 bits (65), Expect = 10.0
 Identities = 22/72 (30%), Positives = 38/72 (52%)
 Frame = +2

Query: 401 SATRVTALTNSKPLSCASFPIESMSASTAALALGSEQSCLKSSYWIPSNAAQLFNTSGST 580
           S T  T+  ++   S AS  I + S+S AA       + L SS  IPS+++ + ++S +T
Sbjct: 2   SFTNNTSSVDTSLSSSASSSIPASSSSAAA------STSLSSSSVIPSSSSSMLSSSSAT 55

Query: 581 ATTATRQELKLS 616
           A +++     LS
Sbjct: 56  AISSSSSSSPLS 67

>YG1F_YEAST (P53214) Hypothetical 57.5 kDa protein in VMA7-RPS25A intergenic|
           region
          Length = 551

 Score = 35.0 bits (79), Expect = 0.24
 Identities = 33/121 (27%), Positives = 60/121 (49%), Gaps = 11/121 (9%)
 Frame = +2

Query: 284 SASSSCAYISVISFAKYAFACGLLTL---------NVGVRRPFSSVNDSATRVTALTNSK 436
           SAS S   I+ +SF  +  +  LLTL         +  ++   SS + S++ VT+ ++S 
Sbjct: 70  SASLSTPSIASVSFTSFPQSSSLLTLSSTLSSELSSSSMQVSSSSTSSSSSEVTSSSSSS 129

Query: 437 PL--SCASFPIESMSASTAALALGSEQSCLKSSYWIPSNAAQLFNTSGSTATTATRQELK 610
            +  S +S  I S S+S     + S  S + SS  + ++++ + +TS ST T ++     
Sbjct: 130 SISPSSSSSTIISSSSSLPTFTVASTSSTVASS-TLSTSSSLVISTSSSTFTFSSESSSS 188

Query: 611 L 613
           L
Sbjct: 189 L 189

>KDC2_DROME (P16912) Protein kinase DC2 (EC 2.7.11.1)|
          Length = 583

 Score = 30.4 bits (67), Expect = 5.8
 Identities = 22/55 (40%), Positives = 32/55 (58%), Gaps = 4/55 (7%)
 Frame = +2

Query: 443 SCASF--PIESMSA-STAALALGSEQ-SCLKSSYWIPSNAAQLFNTSGSTATTAT 595
           +CA F  P+ S +A ST+ L  G+   + + S+Y IPSN +   N S +T TT T
Sbjct: 88  TCARFCTPLSSGTAGSTSKLTTGNGSGNTMTSAYKIPSNNSTTANDSSNTETTFT 142

>YL61_SCHPO (Q8TFG9) Hypothetical serine/threonine-rich protein PB15E9.01c|
           precursor
          Length = 943

 Score = 30.0 bits (66), Expect = 7.6
 Identities = 19/81 (23%), Positives = 42/81 (51%), Gaps = 9/81 (11%)
 Frame = +2

Query: 380 PFSSVNDSATRVTALTNSKPL---------SCASFPIESMSASTAALALGSEQSCLKSSY 532
           P SSV+ + +     T+S PL         S +S P+ S++++TA  A  +  + + S+ 
Sbjct: 323 PLSSVSSANSTTATSTSSTPLSSVNSTTATSASSTPLTSVNSTTATSASSTPLTSVNSTS 382

Query: 533 WIPSNAAQLFNTSGSTATTAT 595
              +++  L + + +T+T+ +
Sbjct: 383 ATSASSTPLTSANSTTSTSVS 403

>PRDX3_MOUSE (P20108) Thioredoxin-dependent peroxide reductase, mitochondrial|
           precursor (EC 1.11.1.15) (Perioredoxin-3) (Antioxidant
           protein 1) (AOP-1) (MER5 protein) (PRX III)
          Length = 257

 Score = 30.0 bits (66), Expect = 7.6
 Identities = 23/65 (35%), Positives = 30/65 (46%), Gaps = 1/65 (1%)
 Frame = +2

Query: 449 ASFPIESMSASTAALALGSEQSCLKSSYWIPS-NAAQLFNTSGSTATTATRQELKLSPYT 625
           AS    S+SAST    + S ++CL    W  S      F+TS S  T A  Q    +PY 
Sbjct: 17  ASAISRSISASTVLRPVASRRTCLTDILWSASAQGKSAFSTSSSFHTPAVTQH---APYF 73

Query: 626 KHWAM 640
           K  A+
Sbjct: 74  KGTAV 78

>MAFF_HUMAN (Q9ULX9) Transcription factor MafF (V-maf musculoaponeurotic|
           fibrosarcoma oncogene homolog F) (U-Maf)
          Length = 164

 Score = 29.6 bits (65), Expect = 10.0
 Identities = 26/101 (25%), Positives = 47/101 (46%), Gaps = 2/101 (1%)
 Frame = -1

Query: 444 LRGFEFVKAVTLVAESFTLENGLLTPTFKVKRPQAKAYFAKEITDMYAQL--LDAESARP 271
           LRG    +   L     TL+N     + +VKR   K    K+ +++  ++  L  E+A  
Sbjct: 41  LRGLSAEEVTRLKQRRRTLKNRGYAASCRVKRVCQKEELQKQKSELEREVDKLARENAAM 100

Query: 270 KL*LHQ*WSK*TVNQGTKTNLSNEQQPGTVLGGVNLITVVK 148
           +L L     K    QG   +++  + P T++   ++IT+VK
Sbjct: 101 RLELDALRGKCEALQGFARSVAAARGPATLVAPASVITIVK 141


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 94,499,679
Number of Sequences: 219361
Number of extensions: 1801895
Number of successful extensions: 4555
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 4398
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4536
length of database: 80,573,946
effective HSP length: 109
effective length of database: 56,663,597
effective search space used: 7536258401
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)