ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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更新日:2016年5月1日

Clone Information

BLAST Search Result

Clone Name rbags9g15
Clone Library Name barley_pub

No. Definition Score
(bits)
E
Value
1TRIPC_HUMAN (Q14669) Thyroid receptor-interacting protein 12 (TR... 103 6e-22
2YDE1_SCHPO (Q10435) Probable ubiquitin fusion degradation protei... 96 8e-20
3UFD4_YEAST (P33202) Ubiquitin fusion degradation protein 4 (UB f... 96 1e-19
4HECD1_HUMAN (Q9ULT8) E3 ubiquitin-protein ligase HECTD1 (HECT do... 88 3e-17
5HUL5_YEAST (P53119) Probable ubiquitin-protein ligase HUL5 (EC 6... 61 4e-09
6UBE3A_HUMAN (Q05086) Ubiquitin-protein ligase E3A (EC 6.3.2.-) (... 59 1e-08
7PUB2_SCHPO (Q9UTG2) E3 ubiquitin--protein ligase pub2 (EC 6.3.2.-) 56 1e-07
8UPL1_ARATH (Q8GY23) E3 ubiquitin protein ligase UPL1 (EC 6.3.2.-... 55 3e-07
9UBE3A_MOUSE (O08759) Ubiquitin-protein ligase E3A (EC 6.3.2.-) (... 54 3e-07
10UPL2_ARATH (Q8H0T4) E3 ubiquitin protein ligase UPL2 (EC 6.3.2.-... 54 6e-07
11WWP2_HUMAN (O00308) NEDD4-like E3 ubiquitin-protein ligase WWP2 ... 53 1e-06
12SMUF1_XENLA (Q9PUN2) Smad ubiquitination regulatory factor 1 (EC... 52 1e-06
13TOM1_YEAST (Q03280) E3 ubiquitin protein ligase TOM1 (EC 6.3.2.-... 52 2e-06
14WWP2_MOUSE (Q9DBH0) NEDD4-like E3 ubiquitin-protein ligase WWP2 ... 52 2e-06
15SMUF1_HUMAN (Q9HCE7) Smad ubiquitination regulatory factor 1 (EC... 51 3e-06
16SMUF1_MOUSE (Q9CUN6) Smad ubiquitination regulatory factor 1 (EC... 51 3e-06
17HUWE1_HUMAN (Q7Z6Z7) HECT, UBA and WWE domain-containing protein... 50 5e-06
18SMUF2_HUMAN (Q9HAU4) Smad ubiquitination regulatory factor 2 (EC... 50 5e-06
19HUWE1_MOUSE (Q7TMY8) HECT, UBA and WWE domain-containing protein... 50 5e-06
20HUWE1_RAT (P51593) HECT, UBA and WWE domain-containing protein 1... 50 5e-06
21K0317_MOUSE (Q8CHG5) Protein KIAA0317 50 5e-06
22K0317_HUMAN (O15033) Protein KIAA0317 50 5e-06
23TOM1_ASHGO (Q756G2) Probable E3 ubiquitin protein ligase TOM1 (E... 50 6e-06
24ITCH_MOUSE (Q8C863) Itchy E3 ubiquitin protein ligase (EC 6.3.2.-) 50 6e-06
25ITCH_HUMAN (Q96J02) Itchy homolog E3 ubiquitin protein ligase (E... 50 6e-06
26UBE3C_MOUSE (Q80U95) Ubiquitin-protein ligase E3C (EC 6.3.2.-) 50 8e-06
27UBE3C_HUMAN (Q15386) Ubiquitin-protein ligase E3C (EC 6.3.2.-) 50 8e-06
28WWP1_HUMAN (Q9H0M0) NEDD4-like E3 ubiquitin-protein ligase WWP1 ... 50 8e-06
29WWP1_MOUSE (Q8BZZ3) NEDD4-like E3 ubiquitin-protein ligase WWP1 ... 50 8e-06
30HUL4_ASHGO (Q757T0) Probable ubiquitin-protein ligase HUL4 (EC 6... 49 1e-05
31NED4L_MOUSE (Q8CFI0) E3 ubiquitin-protein ligase NEDD4-like prot... 49 2e-05
32NED4L_PONPY (Q5RBF2) E3 ubiquitin-protein ligase NEDD4-like prot... 49 2e-05
33SMUF1_DROME (Q9V853) E3 ubiquitin-protein ligase Smurf1 (EC 6.3.... 49 2e-05
34NED4L_HUMAN (Q96PU5) E3 ubiquitin-protein ligase NEDD4-like prot... 49 2e-05
35HUL4_YEAST (P40985) Probable ubiquitin-protein ligase HUL4 (EC 6... 48 2e-05
36HERC3_HUMAN (Q15034) HECT domain and RCC1-like domain protein 3 47 4e-05
37TOM1_NEUCR (Q9P4Z1) E3 ubiquitin protein ligase TOM1-like protei... 47 7e-05
38HERC2_DROME (Q9VR91) HECT domain and RCC1-like domain-containing... 46 9e-05
39PTR1_SCHPO (O13834) E3 ubiquitin protein ligase ptr1 (EC 6.3.2.-... 46 1e-04
40PUB1_SCHPO (Q92462) E3 ubiquitin--protein ligase pub1 (EC 6.3.2.-) 45 2e-04
41PUB3_SCHPO (O14326) E3 ubiquitin--protein ligase pub3 (EC 6.3.2.-) 44 5e-04
42SUDX_DROME (Q9Y0H4) E3 ubiquitin-protein ligase suppressor of de... 43 0.001
43HERC2_HUMAN (O95714) HECT domain and RCC1-like domain-containing... 42 0.002
44HERC2_MOUSE (Q4U2R1) HECT domain and RCC1-like domain-containing... 42 0.002
45NEDD4_RAT (Q62940) E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-) 41 0.003
46NEDD4_MOUSE (P46935) E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2... 41 0.003
47NEDD4_HUMAN (P46934) E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-) 41 0.004
48NEDD4_DROME (Q9VVI3) E3 ubiquitin-protein ligase Nedd-4 (EC 6.3.... 39 0.015
49HYD_DROME (P51592) Ubiquitin--protein ligase hyd (EC 6.3.2.-) (P... 38 0.032
50RSP5_YEAST (P39940) E3 ubiquitin--protein ligase RSP5 (EC 6.3.2.-) 37 0.055
51EDD1_RAT (Q62671) Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hy... 36 0.12
52EDD1_MOUSE (Q80TP3) Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (... 36 0.12
53EDD1_HUMAN (O95071) Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (... 36 0.12
54HUTH_STRGR (P24221) Histidine ammonia-lyase (EC 4.3.1.3) (Histid... 31 3.0
55HERC5_HUMAN (Q9UII4) HECT domain and RCC1-like domain-containing... 31 4.0
56YL61_SCHPO (Q8TFG9) Hypothetical serine/threonine-rich protein P... 30 6.7
57MBN_DROME (P52302) Protein lethal(3)malignant blood neoplasm 1 (... 30 8.8
58RB15B_HUMAN (Q8NDT2) Putative RNA-binding protein 15B (RNA-bindi... 30 8.8
59KNIR_DROME (P10734) Zygotic gap protein knirps 30 8.8

>TRIPC_HUMAN (Q14669) Thyroid receptor-interacting protein 12 (TRIP12)|
          Length = 1992

 Score =  103 bits (256), Expect = 6e-22
 Identities = 58/108 (53%), Positives = 70/108 (64%)
 Frame = -1

Query: 674  AIINLLEIMAEFTPDQQHAFCQFVTGASRLPTGGLAALSPRLTIVRKHPSSGVSALNTSG 495
            A+  L EI++ F  +QQ  F QFVTG+ RLP GG  +L+P LTIVRK          T  
Sbjct: 1895 AVKFLFEILSSFDNEQQRLFLQFVTGSPRLPVGGFRSLNPPLTIVRK----------TFE 1944

Query: 494  VTDAADDDLPSVMTCANYLKLPPYSTKEVMRKKLLYAILEGRGSFDLS 351
             T+  DD LPSVMTC NYLKLP YS+ E+MR+KLL A  EG+ SF LS
Sbjct: 1945 STENPDDFLPSVMTCVNYLKLPDYSSIEIMREKLLIAAREGQQSFHLS 1992



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>YDE1_SCHPO (Q10435) Probable ubiquitin fusion degradation protein C12B10.01c|
          Length = 1647

 Score = 96.3 bits (238), Expect = 8e-20
 Identities = 54/109 (49%), Positives = 68/109 (62%)
 Frame = -1

Query: 677  PAIINLLEIMAEFTPDQQHAFCQFVTGASRLPTGGLAALSPRLTIVRKHPSSGVSALNTS 498
            P I  LL +M++    +Q  F QF+TG+ +LP GG A L+P LT+VR+        LN  
Sbjct: 1549 PTIQRLLTLMSQMNFQEQRDFLQFITGSRKLPIGGFAGLNPPLTVVRR--------LNEP 1600

Query: 497  GVTDAADDDLPSVMTCANYLKLPPYSTKEVMRKKLLYAILEGRGSFDLS 351
                  DD LPSVMTC NYLKLP YS+ EV+  +L  AILEG+GSF LS
Sbjct: 1601 PYVP--DDYLPSVMTCVNYLKLPEYSSSEVLGSRLSKAILEGQGSFHLS 1647



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>UFD4_YEAST (P33202) Ubiquitin fusion degradation protein 4 (UB fusion protein 4)|
          Length = 1483

 Score = 95.5 bits (236), Expect = 1e-19
 Identities = 48/107 (44%), Positives = 70/107 (65%)
 Frame = -1

Query: 671  IINLLEIMAEFTPDQQHAFCQFVTGASRLPTGGLAALSPRLTIVRKHPSSGVSALNTSGV 492
            I + + I++ F   ++  F QF+TG+ +LP GG  +L+P+ T+V KH   G++A      
Sbjct: 1387 IHDFISIISAFGKHERRLFLQFLTGSPKLPIGGFKSLNPKFTVVLKHAEDGLTA------ 1440

Query: 491  TDAADDDLPSVMTCANYLKLPPYSTKEVMRKKLLYAILEGRGSFDLS 351
                D+ LPSVMTCANYLKLP Y++K++MR +L  AI EG G+F LS
Sbjct: 1441 ----DEYLPSVMTCANYLKLPKYTSKDIMRSRLCQAIEEGAGAFLLS 1483



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>HECD1_HUMAN (Q9ULT8) E3 ubiquitin-protein ligase HECTD1 (HECT domain-containing|
            protein 1) (E3 ligase for inhibin receptor) (EULIR)
          Length = 2612

 Score = 87.8 bits (216), Expect = 3e-17
 Identities = 45/101 (44%), Positives = 60/101 (59%)
 Frame = -1

Query: 677  PAIINLLEIMAEFTPDQQHAFCQFVTGASRLPTGGLAALSPRLTIVRKHPSSGVSALNTS 498
            P  +  + ++   + D++ AF QF TG S LP GGLA L PRLT+VRK            
Sbjct: 2520 PGFLRFVRVLCGMSSDERKAFLQFTTGCSTLPPGGLANLHPRLTVVRK------------ 2567

Query: 497  GVTDAADDDLPSVMTCANYLKLPPYSTKEVMRKKLLYAILE 375
               DA D   PSV TC +YLKLP YS++E+MR++LL A +E
Sbjct: 2568 --VDATDASYPSVNTCVHYLKLPEYSSEEIMRERLLAATME 2606



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>HUL5_YEAST (P53119) Probable ubiquitin-protein ligase HUL5 (EC 6.3.2.-)|
          Length = 910

 Score = 60.8 bits (146), Expect = 4e-09
 Identities = 38/109 (34%), Positives = 55/109 (50%), Gaps = 2/109 (1%)
 Frame = -1

Query: 671  IINLLEIMAEFTPDQQHAFCQFVTGASRLPTGGLAALSPRLTIVRKHPSSGVSALNTSGV 492
            I++  E++ EF  +++  F +FVT   + P  G  AL P+                  G+
Sbjct: 820  IVDFWEVLNEFKFEEKLNFLKFVTSVPQAPLQGFKALDPKF-----------------GI 862

Query: 491  TDAADDD--LPSVMTCANYLKLPPYSTKEVMRKKLLYAILEGRGSFDLS 351
             +A  +   LP+  TC N LKLP Y  K ++R+KLLYAI  G   FDLS
Sbjct: 863  RNAGTEKYRLPTASTCVNLLKLPDYRNKTILREKLLYAINSG-ARFDLS 910



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>UBE3A_HUMAN (Q05086) Ubiquitin-protein ligase E3A (EC 6.3.2.-) (E6AP|
            ubiquitin-protein ligase) (Oncogenic protein-associated
            protein E6-AP) (Human papillomavirus E6-associated
            protein) (NY-REN-54 antigen)
          Length = 875

 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 35/97 (36%), Positives = 50/97 (51%)
 Frame = -1

Query: 656  EIMAEFTPDQQHAFCQFVTGASRLPTGGLAALSPRLTIVRKHPSSGVSALNTSGVTDAAD 477
            EI+  FT +Q+  F QF TG  R P GGL  L  ++ I +  P +               
Sbjct: 792  EIVHSFTDEQKRLFLQFTTGTDRAPVGGLGKL--KMIIAKNGPDT--------------- 834

Query: 476  DDLPSVMTCANYLKLPPYSTKEVMRKKLLYAILEGRG 366
            + LP+  TC N L LP YS+KE ++++LL AI   +G
Sbjct: 835  ERLPTSHTCFNVLLLPEYSSKEKLKERLLKAITYAKG 871



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>PUB2_SCHPO (Q9UTG2) E3 ubiquitin--protein ligase pub2 (EC 6.3.2.-)|
          Length = 671

 Score = 55.8 bits (133), Expect = 1e-07
 Identities = 34/102 (33%), Positives = 50/102 (49%)
 Frame = -1

Query: 671 IINLLEIMAEFTPDQQHAFCQFVTGASRLPTGGLAALSPRLTIVRKHPSSGVSALNTSGV 492
           +I   E+++E++P+++    QF TG SRLP  G   +         H S G        V
Sbjct: 577 VIWFWELLSEWSPEKKAKLLQFATGTSRLPLSGFKDM---------HGSDGPRKFTIEKV 627

Query: 491 TDAADDDLPSVMTCANYLKLPPYSTKEVMRKKLLYAILEGRG 366
              +   LP   TC N L +PPY++KE + +KL  AI E  G
Sbjct: 628 GHISQ--LPKAHTCFNRLDIPPYNSKEELEQKLTIAIQETAG 667



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>UPL1_ARATH (Q8GY23) E3 ubiquitin protein ligase UPL1 (EC 6.3.2.-)|
            (Ubiquitin-protein ligase 1)
          Length = 3684

 Score = 54.7 bits (130), Expect = 3e-07
 Identities = 37/108 (34%), Positives = 51/108 (47%), Gaps = 2/108 (1%)
 Frame = -1

Query: 677  PAIINLLEIMAEFTPDQQHAFCQFVTGASRLPTGGLAALSPRLTIVRKHPSSGVSALNTS 498
            P I    E++  F+ +    F QFVTG S++P  G  AL             G+S     
Sbjct: 3583 PVIHWFWEVVKAFSKEDMARFLQFVTGTSKVPLEGFKALQ------------GISGPQRL 3630

Query: 497  GVTDA--ADDDLPSVMTCANYLKLPPYSTKEVMRKKLLYAILEGRGSF 360
             +  A  A + LPS  TC N L LP Y +KE ++++LL AI E    F
Sbjct: 3631 QIHKAYGAPERLPSAHTCFNQLDLPEYQSKEQLQERLLLAIHEASEGF 3678



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>UBE3A_MOUSE (O08759) Ubiquitin-protein ligase E3A (EC 6.3.2.-) (Oncogenic|
            protein-associated protein E6-AP)
          Length = 885

 Score = 54.3 bits (129), Expect = 3e-07
 Identities = 34/97 (35%), Positives = 47/97 (48%)
 Frame = -1

Query: 656  EIMAEFTPDQQHAFCQFVTGASRLPTGGLAALSPRLTIVRKHPSSGVSALNTSGVTDAAD 477
            EI+  FT +Q+  F  F TG  R P GGL  L  ++ I +  P +               
Sbjct: 802  EIVHSFTDEQKRLFLLFTTGTDRAPVGGLGKL--KMIIAKNGPDT--------------- 844

Query: 476  DDLPSVMTCANYLKLPPYSTKEVMRKKLLYAILEGRG 366
            + LP+  TC N L LP YS+KE +  +LL AI   +G
Sbjct: 845  ERLPTSHTCFNVLLLPEYSSKEKLNVRLLKAITYAKG 881



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>UPL2_ARATH (Q8H0T4) E3 ubiquitin protein ligase UPL2 (EC 6.3.2.-)|
            (Ubiquitin-protein ligase 2)
          Length = 3658

 Score = 53.5 bits (127), Expect = 6e-07
 Identities = 36/108 (33%), Positives = 51/108 (47%), Gaps = 2/108 (1%)
 Frame = -1

Query: 677  PAIINLLEIMAEFTPDQQHAFCQFVTGASRLPTGGLAALSPRLTIVRKHPSSGVSALNTS 498
            P I    E++  F+ +    F QFVTG S++P  G  AL             G+S     
Sbjct: 3560 PVIRWFWEVVKAFSKEDMARFLQFVTGTSKVPLEGFKALQ------------GISGPQRL 3607

Query: 497  GVTDA--ADDDLPSVMTCANYLKLPPYSTKEVMRKKLLYAILEGRGSF 360
             +  A  + + LPS  TC N L LP Y +KE ++++LL AI E    F
Sbjct: 3608 QIHKAYGSPERLPSAHTCFNQLDLPEYQSKEQVQERLLLAIHEANEGF 3655



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>WWP2_HUMAN (O00308) NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 6.3.2.-) (WW|
            domain-containing protein 2) (Atrophin-1-interacting
            protein 2) (AIP2)
          Length = 870

 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 36/97 (37%), Positives = 47/97 (48%)
 Frame = -1

Query: 656  EIMAEFTPDQQHAFCQFVTGASRLPTGGLAALSPRLTIVRKHPSSGVSALNTSGVTDAAD 477
            +++ E   +++    QFVTG  RLP GG A L           S+G        V    +
Sbjct: 781  QVVKEMDNEKRIRLLQFVTGTCRLPVGGFAELIG---------SNGPQKFCIDKV--GKE 829

Query: 476  DDLPSVMTCANYLKLPPYSTKEVMRKKLLYAILEGRG 366
              LP   TC N L LPPY + E +R+KLLYAI E  G
Sbjct: 830  TWLPRSHTCFNRLDLPPYKSYEQLREKLLYAIEETEG 866



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>SMUF1_XENLA (Q9PUN2) Smad ubiquitination regulatory factor 1 (EC 6.3.2.-)|
           (Ubiquitin--protein ligase SMURF1) (Smad-specific E3
           ubiquitin ligase) (xSMURF1)
          Length = 731

 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 33/99 (33%), Positives = 51/99 (51%), Gaps = 2/99 (2%)
 Frame = -1

Query: 656 EIMAEFTPDQQHAFCQFVTGASRLPTGGLAALSPRLTIVRKHPSSGVSA--LNTSGVTDA 483
           + +  F  +++    QFVTG++R+P  G  AL           S+G +   L T  + DA
Sbjct: 638 QAVESFDEERRARLLQFVTGSTRVPLQGFKALQG---------STGAAGPRLFTIHLIDA 688

Query: 482 ADDDLPSVMTCANYLKLPPYSTKEVMRKKLLYAILEGRG 366
             D+LP   TC N + +PPY + E + +KLL A+ E  G
Sbjct: 689 NTDNLPKAHTCFNRIDIPPYESYEKLYEKLLTAVEETSG 727



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>TOM1_YEAST (Q03280) E3 ubiquitin protein ligase TOM1 (EC 6.3.2.-)|
            (Temperature-dependent organization in mitotic nucleus
            protein 1) (Suppressor of snRNA protein 2)
          Length = 3268

 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 34/99 (34%), Positives = 47/99 (47%), Gaps = 2/99 (2%)
 Frame = -1

Query: 641  FTPDQQHAFCQFVTGASRLPTGGLAALSPRLTIVRKHPSSGVSALNTSGVTD--AADDDL 468
            F  +++    QFVTG S++P  G   LS            GV+ +    +     + + L
Sbjct: 3182 FDAEERAKLLQFVTGTSKVPLNGFKELS------------GVNGVCKFSIHRDFGSSERL 3229

Query: 467  PSVMTCANYLKLPPYSTKEVMRKKLLYAILEGRGSFDLS 351
            PS  TC N L LPPY + E +R  LL AI EG   F L+
Sbjct: 3230 PSSHTCFNQLNLPPYESYETLRGSLLLAINEGHEGFGLA 3268



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>WWP2_MOUSE (Q9DBH0) NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 6.3.2.-) (WW|
            domain-containing protein 2)
          Length = 870

 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 35/97 (36%), Positives = 47/97 (48%)
 Frame = -1

Query: 656  EIMAEFTPDQQHAFCQFVTGASRLPTGGLAALSPRLTIVRKHPSSGVSALNTSGVTDAAD 477
            +++ E   +++    QFVTG  RLP GG A L           S+G        V    +
Sbjct: 781  QVVKEMDNEKRIRLLQFVTGTCRLPVGGFAELIG---------SNGPQKFCIDRV--GKE 829

Query: 476  DDLPSVMTCANYLKLPPYSTKEVMRKKLLYAILEGRG 366
              LP   TC N L LPPY + E +++KLLYAI E  G
Sbjct: 830  TWLPRSHTCFNRLDLPPYKSYEQLKEKLLYAIEETEG 866



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>SMUF1_HUMAN (Q9HCE7) Smad ubiquitination regulatory factor 1 (EC 6.3.2.-)|
           (Ubiquitin--protein ligase SMURF1) (Smad-specific E3
           ubiquitin ligase 1) (hSMURF1)
          Length = 757

 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 33/94 (35%), Positives = 49/94 (52%), Gaps = 2/94 (2%)
 Frame = -1

Query: 641 FTPDQQHAFCQFVTGASRLPTGGLAALSPRLTIVRKHPSSGVSA--LNTSGVTDAADDDL 468
           F  +++    QFVTG++R+P  G  AL           S+G +   L T  + DA  D+L
Sbjct: 669 FDEERRARLLQFVTGSTRVPLQGFKALQG---------STGAAGPRLFTIHLIDANTDNL 719

Query: 467 PSVMTCANYLKLPPYSTKEVMRKKLLYAILEGRG 366
           P   TC N + +PPY + E + +KLL A+ E  G
Sbjct: 720 PKAHTCFNRIDIPPYESYEKLYEKLLTAVEETCG 753



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>SMUF1_MOUSE (Q9CUN6) Smad ubiquitination regulatory factor 1 (EC 6.3.2.-)|
           (Ubiquitin--protein ligase SMURF1) (Smad-specific E3
           ubiquitin ligase 1)
          Length = 731

 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 33/94 (35%), Positives = 49/94 (52%), Gaps = 2/94 (2%)
 Frame = -1

Query: 641 FTPDQQHAFCQFVTGASRLPTGGLAALSPRLTIVRKHPSSGVSA--LNTSGVTDAADDDL 468
           F  +++    QFVTG++R+P  G  AL           S+G +   L T  + DA  D+L
Sbjct: 643 FDEERRARLLQFVTGSTRVPLQGFKALQG---------STGAAGPRLFTIHLIDANTDNL 693

Query: 467 PSVMTCANYLKLPPYSTKEVMRKKLLYAILEGRG 366
           P   TC N + +PPY + E + +KLL A+ E  G
Sbjct: 694 PKAHTCFNRIDIPPYESYEKLYEKLLTAVEETCG 727



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>HUWE1_HUMAN (Q7Z6Z7) HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-)|
            (E3 ubiquitin protein ligase URE-B1) (Mcl-1 ubiquitin
            ligase E3) (Mule) (ARF-binding protein 1) (ARF-BP1)
          Length = 4374

 Score = 50.4 bits (119), Expect = 5e-06
 Identities = 35/102 (34%), Positives = 47/102 (46%), Gaps = 2/102 (1%)
 Frame = -1

Query: 650  MAEFTPDQQHAFCQFVTGASRLPTGGLAALSPRLTIVRKHPSSGVSALNTSGV--TDAAD 477
            +  F    +  F QFVTG S++P  G AAL             G++ +    +   D + 
Sbjct: 4285 LRSFDQADRAKFLQFVTGTSKVPLQGFAALE------------GMNGIQKFQIHRDDRST 4332

Query: 476  DDLPSVMTCANYLKLPPYSTKEVMRKKLLYAILEGRGSFDLS 351
            D LPS  TC N L LP Y + E +R  LL AI E    F L+
Sbjct: 4333 DRLPSAHTCFNQLDLPAYESFEKLRHMLLLAIQECSEGFGLA 4374



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>SMUF2_HUMAN (Q9HAU4) Smad ubiquitination regulatory factor 2 (EC 6.3.2.-)|
           (Ubiquitin--protein ligase SMURF2) (Smad-specific E3
           ubiquitin ligase 2) (hSMURF2)
          Length = 748

 Score = 50.4 bits (119), Expect = 5e-06
 Identities = 33/96 (34%), Positives = 47/96 (48%), Gaps = 4/96 (4%)
 Frame = -1

Query: 641 FTPDQQHAFCQFVTGASRLPTGGLAALS----PRLTIVRKHPSSGVSALNTSGVTDAADD 474
           F  +++    QFVTG+SR+P  G  AL     PRL  + +               DA  +
Sbjct: 663 FDEERRARLLQFVTGSSRVPLQGFKALQGAAGPRLFTIHQ--------------IDACTN 708

Query: 473 DLPSVMTCANYLKLPPYSTKEVMRKKLLYAILEGRG 366
           +LP   TC N + +PPY + E + +KLL AI E  G
Sbjct: 709 NLPKAHTCFNRIDIPPYESYEKLYEKLLTAIEETCG 744



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>HUWE1_MOUSE (Q7TMY8) HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-)|
            (E3 ubiquitin protein ligase URE-B1) (E3Histone)
          Length = 4377

 Score = 50.4 bits (119), Expect = 5e-06
 Identities = 35/102 (34%), Positives = 47/102 (46%), Gaps = 2/102 (1%)
 Frame = -1

Query: 650  MAEFTPDQQHAFCQFVTGASRLPTGGLAALSPRLTIVRKHPSSGVSALNTSGV--TDAAD 477
            +  F    +  F QFVTG S++P  G AAL             G++ +    +   D + 
Sbjct: 4288 LRSFDQADRAKFLQFVTGTSKVPLQGFAALE------------GMNGIQKFQIHRDDRST 4335

Query: 476  DDLPSVMTCANYLKLPPYSTKEVMRKKLLYAILEGRGSFDLS 351
            D LPS  TC N L LP Y + E +R  LL AI E    F L+
Sbjct: 4336 DRLPSAHTCFNQLDLPAYESFEKLRHMLLLAIQECSEGFGLA 4377



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>HUWE1_RAT (P51593) HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-)|
           (E3 ubiquitin protein ligase URE-B1) (Upstream
           regulatory element-binding protein 1) (Fragment)
          Length = 322

 Score = 50.4 bits (119), Expect = 5e-06
 Identities = 35/102 (34%), Positives = 47/102 (46%), Gaps = 2/102 (1%)
 Frame = -1

Query: 650 MAEFTPDQQHAFCQFVTGASRLPTGGLAALSPRLTIVRKHPSSGVSALNTSGV--TDAAD 477
           +  F    +  F QFVTG S++P  G AAL             G++ +    +   D + 
Sbjct: 233 LRSFDQADRAKFLQFVTGTSKVPLQGFAALE------------GMNGIQKFQIHRDDRST 280

Query: 476 DDLPSVMTCANYLKLPPYSTKEVMRKKLLYAILEGRGSFDLS 351
           D LPS  TC N L LP Y + E +R  LL AI E    F L+
Sbjct: 281 DRLPSAHTCFNQLDLPAYESFEKLRHMLLLAIQECSEGFGLA 322



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>K0317_MOUSE (Q8CHG5) Protein KIAA0317|
          Length = 823

 Score = 50.4 bits (119), Expect = 5e-06
 Identities = 32/100 (32%), Positives = 45/100 (45%)
 Frame = -1

Query: 653 IMAEFTPDQQHAFCQFVTGASRLPTGGLAALSPRLTIVRKHPSSGVSALNTSGVTDAADD 474
           +++  T ++     QF TG+S+LP GG AAL P   I+     S                
Sbjct: 739 VVSSLTQEELARLLQFTTGSSQLPPGGFAALCPSFQIIAAPTHS---------------- 782

Query: 473 DLPSVMTCANYLKLPPYSTKEVMRKKLLYAILEGRGSFDL 354
            LP+  TC N L LP Y + E + + L  AI EG   F +
Sbjct: 783 TLPTAHTCFNQLCLPTYDSYEEVHRMLQLAISEGCEGFGM 822



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>K0317_HUMAN (O15033) Protein KIAA0317|
          Length = 823

 Score = 50.4 bits (119), Expect = 5e-06
 Identities = 32/100 (32%), Positives = 45/100 (45%)
 Frame = -1

Query: 653 IMAEFTPDQQHAFCQFVTGASRLPTGGLAALSPRLTIVRKHPSSGVSALNTSGVTDAADD 474
           +++  T ++     QF TG+S+LP GG AAL P   I+     S                
Sbjct: 739 VVSSLTQEELARLLQFTTGSSQLPPGGFAALCPSFQIIAAPTHS---------------- 782

Query: 473 DLPSVMTCANYLKLPPYSTKEVMRKKLLYAILEGRGSFDL 354
            LP+  TC N L LP Y + E + + L  AI EG   F +
Sbjct: 783 TLPTAHTCFNQLCLPTYDSYEEVHRMLQLAISEGCEGFGM 822



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>TOM1_ASHGO (Q756G2) Probable E3 ubiquitin protein ligase TOM1 (EC 6.3.2.-)|
          Length = 3258

 Score = 50.1 bits (118), Expect = 6e-06
 Identities = 33/99 (33%), Positives = 47/99 (47%), Gaps = 2/99 (2%)
 Frame = -1

Query: 641  FTPDQQHAFCQFVTGASRLPTGGLAALSPRLTIVRKHPSSGVSALNTSGVTD--AADDDL 468
            F  +++    QFVTG S++P  G   LS            GV+ ++   +     + D L
Sbjct: 3172 FDKEERAKLLQFVTGTSKVPLNGFKELS------------GVNGISKFSIHRDYGSIDRL 3219

Query: 467  PSVMTCANYLKLPPYSTKEVMRKKLLYAILEGRGSFDLS 351
            PS  TC N L LP Y + E +R  LL AI EG   F ++
Sbjct: 3220 PSSHTCFNQLDLPAYDSYETLRGSLLLAINEGHEGFGIA 3258



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>ITCH_MOUSE (Q8C863) Itchy E3 ubiquitin protein ligase (EC 6.3.2.-)|
          Length = 864

 Score = 50.1 bits (118), Expect = 6e-06
 Identities = 34/97 (35%), Positives = 47/97 (48%)
 Frame = -1

Query: 656  EIMAEFTPDQQHAFCQFVTGASRLPTGGLAALSPRLTIVRKHPSSGVSALNTSGVTDAAD 477
            + + E   +++    QFVTG  RLP GG A L           S+G        V    +
Sbjct: 775  QFVKEIDNEKRMRLLQFVTGTCRLPVGGFADLMG---------SNGPQKFCIEKV--GKE 823

Query: 476  DDLPSVMTCANYLKLPPYSTKEVMRKKLLYAILEGRG 366
            + LP   TC N L LPPY + E +++KLL+AI E  G
Sbjct: 824  NWLPRSHTCFNRLDLPPYKSYEQLKEKLLFAIEETEG 860



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>ITCH_HUMAN (Q96J02) Itchy homolog E3 ubiquitin protein ligase (EC 6.3.2.-)|
            (Itch) (Atrophin-1-interacting protein 4) (AIP4)
            (NFE2-associated polypeptide 1) (NAPP1)
          Length = 903

 Score = 50.1 bits (118), Expect = 6e-06
 Identities = 34/97 (35%), Positives = 47/97 (48%)
 Frame = -1

Query: 656  EIMAEFTPDQQHAFCQFVTGASRLPTGGLAALSPRLTIVRKHPSSGVSALNTSGVTDAAD 477
            + + E   +++    QFVTG  RLP GG A L           S+G        V    +
Sbjct: 814  QFVKEIDNEKRMRLLQFVTGTCRLPVGGFADLMG---------SNGPQKFCIEKV--GKE 862

Query: 476  DDLPSVMTCANYLKLPPYSTKEVMRKKLLYAILEGRG 366
            + LP   TC N L LPPY + E +++KLL+AI E  G
Sbjct: 863  NWLPRSHTCFNRLDLPPYKSYEQLKEKLLFAIEETEG 899



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>UBE3C_MOUSE (Q80U95) Ubiquitin-protein ligase E3C (EC 6.3.2.-)|
          Length = 1083

 Score = 49.7 bits (117), Expect = 8e-06
 Identities = 37/109 (33%), Positives = 51/109 (46%)
 Frame = -1

Query: 677  PAIINLLEIMAEFTPDQQHAFCQFVTGASRLPTGGLAALSPRLTIVRKHPSSGVSALNTS 498
            P I     ++  FT +++    +FVT  SR P  G   L P   I      +G S L   
Sbjct: 991  PVIKIFWRVVEGFTDEEKRKLLKFVTSCSRPPLLGFKELYPAFCI-----HNGGSDL--- 1042

Query: 497  GVTDAADDDLPSVMTCANYLKLPPYSTKEVMRKKLLYAILEGRGSFDLS 351
                   + LP+  TC N LKLP +  + ++R KLLYAI E    F+LS
Sbjct: 1043 -------ERLPTASTCMNLLKLPEFYDEALLRSKLLYAI-ECAAGFELS 1083



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>UBE3C_HUMAN (Q15386) Ubiquitin-protein ligase E3C (EC 6.3.2.-)|
          Length = 1083

 Score = 49.7 bits (117), Expect = 8e-06
 Identities = 37/109 (33%), Positives = 51/109 (46%)
 Frame = -1

Query: 677  PAIINLLEIMAEFTPDQQHAFCQFVTGASRLPTGGLAALSPRLTIVRKHPSSGVSALNTS 498
            P I     ++  FT +++    +FVT  SR P  G   L P   I      +G S L   
Sbjct: 991  PVIKVFWRVVEGFTDEEKRKLLKFVTSCSRPPLLGFKELYPAFCI-----HNGGSDL--- 1042

Query: 497  GVTDAADDDLPSVMTCANYLKLPPYSTKEVMRKKLLYAILEGRGSFDLS 351
                   + LP+  TC N LKLP +  + ++R KLLYAI E    F+LS
Sbjct: 1043 -------ERLPTASTCMNLLKLPEFYDETLLRSKLLYAI-ECAAGFELS 1083



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>WWP1_HUMAN (Q9H0M0) NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW|
            domain-containing protein 1) (Atropin-1-interacting
            protein 5) (AIP5)
          Length = 922

 Score = 49.7 bits (117), Expect = 8e-06
 Identities = 37/102 (36%), Positives = 47/102 (46%)
 Frame = -1

Query: 671  IINLLEIMAEFTPDQQHAFCQFVTGASRLPTGGLAALSPRLTIVRKHPSSGVSALNTSGV 492
            II   + + E   + +    QFVTG  RLP GG A L           S+G        V
Sbjct: 828  IIWFWQFVKETDNEVRMRLLQFVTGTCRLPLGGFAELMG---------SNGPQKFCIEKV 878

Query: 491  TDAADDDLPSVMTCANYLKLPPYSTKEVMRKKLLYAILEGRG 366
                D  LP   TC N L LPPY + E +++KLL+AI E  G
Sbjct: 879  --GKDTWLPRSHTCFNRLDLPPYKSYEQLKEKLLFAIEETEG 918



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>WWP1_MOUSE (Q8BZZ3) NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW|
            domain-containing protein 1)
          Length = 918

 Score = 49.7 bits (117), Expect = 8e-06
 Identities = 37/102 (36%), Positives = 47/102 (46%)
 Frame = -1

Query: 671  IINLLEIMAEFTPDQQHAFCQFVTGASRLPTGGLAALSPRLTIVRKHPSSGVSALNTSGV 492
            II   + + E   + +    QFVTG  RLP GG A L           S+G        V
Sbjct: 824  IIWFWQFVKETDNEVRMRLLQFVTGTCRLPLGGFAELMG---------SNGPQKFCIEKV 874

Query: 491  TDAADDDLPSVMTCANYLKLPPYSTKEVMRKKLLYAILEGRG 366
                D  LP   TC N L LPPY + E +++KLL+AI E  G
Sbjct: 875  --GKDTWLPRSHTCFNRLDLPPYKSYEQLKEKLLFAIEETEG 914



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>HUL4_ASHGO (Q757T0) Probable ubiquitin-protein ligase HUL4 (EC 6.3.2.-) (HECT|
            ubiquitin ligase 4)
          Length = 839

 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 31/104 (29%), Positives = 47/104 (45%)
 Frame = -1

Query: 677  PAIINLLEIMAEFTPDQQHAFCQFVTGASRLPTGGLAALSPRLTIVRKHPSSGVSALNTS 498
            P +    EI++E    QQ     FVTG+ R+P  G+  +  R++ +R             
Sbjct: 749  PVVQWFWEILSEMEYPQQRKLLHFVTGSDRVPATGVTTIPFRISRIR------------- 795

Query: 497  GVTDAADDDLPSVMTCANYLKLPPYSTKEVMRKKLLYAILEGRG 366
                +  D LP   TC N + L  Y  KE +R KL+ A+ E +G
Sbjct: 796  ----SGADRLPLSHTCFNEICLHEYKDKETLRNKLIIALEESQG 835



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>NED4L_MOUSE (Q8CFI0) E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-)|
            (Nedd4-2) (NEDD4.2)
          Length = 1004

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 32/86 (37%), Positives = 41/86 (47%), Gaps = 4/86 (4%)
 Frame = -1

Query: 611  QFVTGASRLPTGGLAAL----SPRLTIVRKHPSSGVSALNTSGVTDAADDDLPSVMTCAN 444
            QFVTG SR+P  G A L     P+L  + +  S                + LP   TC N
Sbjct: 929  QFVTGTSRVPMNGFAELYGSNGPQLFTIEQWGSP---------------EKLPRAHTCFN 973

Query: 443  YLKLPPYSTKEVMRKKLLYAILEGRG 366
             L LPPY T E +R+KLL A+   +G
Sbjct: 974  RLDLPPYETFEDLREKLLMAVENAQG 999



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>NED4L_PONPY (Q5RBF2) E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-)|
          Length = 959

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 32/86 (37%), Positives = 41/86 (47%), Gaps = 4/86 (4%)
 Frame = -1

Query: 611  QFVTGASRLPTGGLAAL----SPRLTIVRKHPSSGVSALNTSGVTDAADDDLPSVMTCAN 444
            QFVTG SR+P  G A L     P+L  + +  S                + LP   TC N
Sbjct: 884  QFVTGTSRVPMNGFAELYGSNGPQLFTIEQWGSP---------------EKLPRAHTCFN 928

Query: 443  YLKLPPYSTKEVMRKKLLYAILEGRG 366
             L LPPY T E +R+KLL A+   +G
Sbjct: 929  RLDLPPYETFEDLREKLLMAVENAQG 954



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>SMUF1_DROME (Q9V853) E3 ubiquitin-protein ligase Smurf1 (EC 6.3.2.-) (Smad|
            ubiquitination regulatory factor 1 homolog) (DSmurf)
            (Lethal with a checkpoint kinase protein)
          Length = 1061

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 29/97 (29%), Positives = 44/97 (45%)
 Frame = -1

Query: 656  EIMAEFTPDQQHAFCQFVTGASRLPTGGLAALSPRLTIVRKHPSSGVSALNTSGVTDAAD 477
            +++  ++ + +    QFVTG+SR+P  G  AL      V      G          D   
Sbjct: 967  QVVESYSSEMRARLLQFVTGSSRVPLQGFRALQGSTGAV------GPRLFTIHLTADVPT 1020

Query: 476  DDLPSVMTCANYLKLPPYSTKEVMRKKLLYAILEGRG 366
             +LP   TC N + LPPY T +++  KL  A+ E  G
Sbjct: 1021 QNLPKAHTCFNRIDLPPYETYQLLCDKLTQAVEETCG 1057



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>NED4L_HUMAN (Q96PU5) E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-)|
            (Nedd4-2) (NEDD4.2)
          Length = 975

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 32/86 (37%), Positives = 41/86 (47%), Gaps = 4/86 (4%)
 Frame = -1

Query: 611  QFVTGASRLPTGGLAAL----SPRLTIVRKHPSSGVSALNTSGVTDAADDDLPSVMTCAN 444
            QFVTG SR+P  G A L     P+L  + +  S                + LP   TC N
Sbjct: 900  QFVTGTSRVPMNGFAELYGSNGPQLFTIEQWGSP---------------EKLPRAHTCFN 944

Query: 443  YLKLPPYSTKEVMRKKLLYAILEGRG 366
             L LPPY T E +R+KLL A+   +G
Sbjct: 945  RLDLPPYETFEDLREKLLMAVENAQG 970



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>HUL4_YEAST (P40985) Probable ubiquitin-protein ligase HUL4 (EC 6.3.2.-) (HECT|
            ubiquitin ligase 4)
          Length = 892

 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 30/97 (30%), Positives = 47/97 (48%)
 Frame = -1

Query: 656  EIMAEFTPDQQHAFCQFVTGASRLPTGGLAALSPRLTIVRKHPSSGVSALNTSGVTDAAD 477
            EI+  +    Q    QFVT + R+P  G++ +  +++++  H S                
Sbjct: 808  EIIESWDYPLQKKLLQFVTASDRIPATGISTIPFKISLLGSHDS---------------- 851

Query: 476  DDLPSVMTCANYLKLPPYSTKEVMRKKLLYAILEGRG 366
            DDLP   TC N + L  YS+K+ +  KLL+AI E  G
Sbjct: 852  DDLPLAHTCFNEICLWNYSSKKKLELKLLWAINESEG 888



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>HERC3_HUMAN (Q15034) HECT domain and RCC1-like domain protein 3|
          Length = 1050

 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 31/99 (31%), Positives = 49/99 (49%)
 Frame = -1

Query: 677  PAIINLLEIMAEFTPDQQHAFCQFVTGASRLPTGGLAALSPRLTIVRKHPSSGVSALNTS 498
            P +    E   EF  +++  F  F+TG+ R+P  G+A+L     IV +  +SG       
Sbjct: 960  PTVKLFWETFHEFPLEKKKKFLLFLTGSDRIPIYGMASLQ----IVIQSTASG------- 1008

Query: 497  GVTDAADDDLPSVMTCANYLKLPPYSTKEVMRKKLLYAI 381
                  ++ LP   TC N L LP YS+KE++  +L  A+
Sbjct: 1009 ------EEYLPVAHTCYNLLDLPKYSSKEILSARLTQAL 1041



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>TOM1_NEUCR (Q9P4Z1) E3 ubiquitin protein ligase TOM1-like protein (EC 6.3.2.-)|
          Length = 4065

 Score = 46.6 bits (109), Expect = 7e-05
 Identities = 33/94 (35%), Positives = 41/94 (43%)
 Frame = -1

Query: 641  FTPDQQHAFCQFVTGASRLPTGGLAALSPRLTIVRKHPSSGVSALNTSGVTDAADDDLPS 462
            F  ++     QFVTG S++P  G   L            +GVS  N       + D LPS
Sbjct: 3979 FDKEELAKLLQFVTGTSKVPLNGFKELEGM---------NGVSRFNIHR-DYGSKDRLPS 4028

Query: 461  VMTCANYLKLPPYSTKEVMRKKLLYAILEGRGSF 360
              TC N L LP Y   E +R +LL AI  G   F
Sbjct: 4029 SHTCFNQLDLPEYENYETLRSQLLKAITAGSDYF 4062



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>HERC2_DROME (Q9VR91) HECT domain and RCC1-like domain-containing protein 2|
          Length = 4912

 Score = 46.2 bits (108), Expect = 9e-05
 Identities = 34/95 (35%), Positives = 46/95 (48%), Gaps = 3/95 (3%)
 Frame = -1

Query: 656  EIMAEFTPDQQHAFCQFVTGASRLPTGGLAALSPR---LTIVRKHPSSGVSALNTSGVTD 486
            E+M EFT  ++  F +FV G +RLP   +A    R   L ++ K+P              
Sbjct: 4795 EVMEEFTNQERSLFLRFVWGRTRLPRT-IADFRGRDFVLQVLEKNPP------------- 4840

Query: 485  AADDDLPSVMTCANYLKLPPYSTKEVMRKKLLYAI 381
              D  LP   TC   LK+P YS K V+ +KL YAI
Sbjct: 4841 --DHFLPESYTCFFLLKMPRYSCKAVLLEKLKYAI 4873



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>PTR1_SCHPO (O13834) E3 ubiquitin protein ligase ptr1 (EC 6.3.2.-) (Poly(A)+ RNA|
            transport protein 1)
          Length = 3227

 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 31/94 (32%), Positives = 39/94 (41%)
 Frame = -1

Query: 641  FTPDQQHAFCQFVTGASRLPTGGLAALSPRLTIVRKHPSSGVSALNTSGVTDAADDDLPS 462
            F  +++    QF TG S++P  G   L       R +      +LN           LP 
Sbjct: 3141 FDEEERAKLLQFATGTSKVPLNGFKELEGMSGFQRFNIHKSYGSLNR----------LPQ 3190

Query: 461  VMTCANYLKLPPYSTKEVMRKKLLYAILEGRGSF 360
              TC N L LP Y T E +R  LL AI EG   F
Sbjct: 3191 SHTCFNQLDLPEYDTYEQLRSMLLTAINEGSEGF 3224



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>PUB1_SCHPO (Q92462) E3 ubiquitin--protein ligase pub1 (EC 6.3.2.-)|
          Length = 767

 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 31/101 (30%), Positives = 45/101 (44%), Gaps = 4/101 (3%)
 Frame = -1

Query: 656 EIMAEFTPDQQHAFCQFVTGASRLPTGGLAALS----PRLTIVRKHPSSGVSALNTSGVT 489
           E+M E++ +++    QF TG SR+P  G   L     PR   + K               
Sbjct: 678 ELMDEWSNEKKSRLLQFTTGTSRIPVNGFKDLQGSDGPRKFTIEKA-------------- 723

Query: 488 DAADDDLPSVMTCANYLKLPPYSTKEVMRKKLLYAILEGRG 366
               + LP   TC N L LPPY++K+ +  KL  A+ E  G
Sbjct: 724 -GEPNKLPKAHTCFNRLDLPPYTSKKDLDHKLSIAVEETIG 763



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>PUB3_SCHPO (O14326) E3 ubiquitin--protein ligase pub3 (EC 6.3.2.-)|
          Length = 786

 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 31/103 (30%), Positives = 42/103 (40%), Gaps = 4/103 (3%)
 Frame = -1

Query: 677 PAIINLLEIMAEFTPDQQHAFCQFVTGASRLPTGGLAALS----PRLTIVRKHPSSGVSA 510
           P I    EI+A +  + +    QF TG SR+P  G   L     PR   + K        
Sbjct: 690 PVIKWFWEIIAGWKNEDRSKLLQFATGTSRIPVNGFRDLQGSDGPRKFTIEKA------- 742

Query: 509 LNTSGVTDAADDDLPSVMTCANYLKLPPYSTKEVMRKKLLYAI 381
                      D LP   TC N L LP Y +K+ + +KL  A+
Sbjct: 743 --------GTPDQLPVAHTCFNRLDLPDYPSKDTLHEKLSLAV 777



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>SUDX_DROME (Q9Y0H4) E3 ubiquitin-protein ligase suppressor of deltex (EC|
            6.3.2.-)
          Length = 949

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 31/97 (31%), Positives = 44/97 (45%)
 Frame = -1

Query: 656  EIMAEFTPDQQHAFCQFVTGASRLPTGGLAALSPRLTIVRKHPSSGVSALNTSGVTDAAD 477
            + + E   +++    QFVTG  R+P GG A L           S+G        V    +
Sbjct: 860  QFVRETDNEKRARLLQFVTGTCRVPVGGFAELMG---------SNGPQRFCIEKV--GKE 908

Query: 476  DDLPSVMTCANYLKLPPYSTKEVMRKKLLYAILEGRG 366
              LP   TC N L LPPY + + + +KL +AI E  G
Sbjct: 909  TWLPRSHTCFNRLDLPPYKSYDQLVEKLTFAIEETEG 945



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>HERC2_HUMAN (O95714) HECT domain and RCC1-like domain-containing protein 2|
          Length = 4834

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 30/92 (32%), Positives = 44/92 (47%)
 Frame = -1

Query: 656  EIMAEFTPDQQHAFCQFVTGASRLPTGGLAALSPRLTIVRKHPSSGVSALNTSGVTDAAD 477
            E+M  F+  ++  F +FV G +RLP   +A    R  +++                +  D
Sbjct: 4706 EVMESFSNTERSLFLRFVWGRTRLPRT-IADFRGRDFVIQ-----------VLDKYNPPD 4753

Query: 476  DDLPSVMTCANYLKLPPYSTKEVMRKKLLYAI 381
              LP   TC   LKLP YS K+V+ +KL YAI
Sbjct: 4754 HFLPESYTCFFLLKLPRYSCKQVLEEKLKYAI 4785



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>HERC2_MOUSE (Q4U2R1) HECT domain and RCC1-like domain-containing protein 2|
          Length = 4836

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 30/92 (32%), Positives = 44/92 (47%)
 Frame = -1

Query: 656  EIMAEFTPDQQHAFCQFVTGASRLPTGGLAALSPRLTIVRKHPSSGVSALNTSGVTDAAD 477
            E+M  F+  ++  F +FV G +RLP   +A    R  +++                +  D
Sbjct: 4708 EVMESFSNTERSLFLRFVWGRTRLPRT-IADFRGRDFVIQ-----------VLDKYNPPD 4755

Query: 476  DDLPSVMTCANYLKLPPYSTKEVMRKKLLYAI 381
              LP   TC   LKLP YS K+V+ +KL YAI
Sbjct: 4756 HFLPESYTCFFLLKLPRYSCKQVLEEKLKYAI 4787



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>NEDD4_RAT (Q62940) E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-)|
          Length = 887

 Score = 41.2 bits (95), Expect = 0.003
 Identities = 29/82 (35%), Positives = 37/82 (45%)
 Frame = -1

Query: 611  QFVTGASRLPTGGLAALSPRLTIVRKHPSSGVSALNTSGVTDAADDDLPSVMTCANYLKL 432
            QFVTG SR+P  G A L         + S+G  +           D LP   TC N L L
Sbjct: 812  QFVTGTSRVPMNGFAEL---------YGSNGPQSFTVEQW--GTPDKLPRAHTCFNRLDL 860

Query: 431  PPYSTKEVMRKKLLYAILEGRG 366
            PPY + + +  KL  AI   +G
Sbjct: 861  PPYESFDELWDKLQMAIENTQG 882



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>NEDD4_MOUSE (P46935) E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-) (Neural|
            precursor cell expressed developmentally down-regulated
            protein 4)
          Length = 887

 Score = 41.2 bits (95), Expect = 0.003
 Identities = 29/82 (35%), Positives = 37/82 (45%)
 Frame = -1

Query: 611  QFVTGASRLPTGGLAALSPRLTIVRKHPSSGVSALNTSGVTDAADDDLPSVMTCANYLKL 432
            QFVTG SR+P  G A L         + S+G  +           D LP   TC N L L
Sbjct: 812  QFVTGTSRVPMNGFAEL---------YGSNGPQSFTVEQW--GTPDKLPRAHTCFNRLDL 860

Query: 431  PPYSTKEVMRKKLLYAILEGRG 366
            PPY + + +  KL  AI   +G
Sbjct: 861  PPYESFDELWDKLQMAIENTQG 882



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>NEDD4_HUMAN (P46934) E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-)|
          Length = 1000

 Score = 40.8 bits (94), Expect = 0.004
 Identities = 29/82 (35%), Positives = 37/82 (45%)
 Frame = -1

Query: 611  QFVTGASRLPTGGLAALSPRLTIVRKHPSSGVSALNTSGVTDAADDDLPSVMTCANYLKL 432
            QFVTG SR+P  G A L         + S+G  +           + LP   TC N L L
Sbjct: 925  QFVTGTSRVPMNGFAEL---------YGSNGPQSFTVEQW--GTPEKLPRAHTCFNRLDL 973

Query: 431  PPYSTKEVMRKKLLYAILEGRG 366
            PPY + E +  KL  AI   +G
Sbjct: 974  PPYESFEELWDKLQMAIENTQG 995



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>NEDD4_DROME (Q9VVI3) E3 ubiquitin-protein ligase Nedd-4 (EC 6.3.2.-) (DNedd4)|
          Length = 1007

 Score = 38.9 bits (89), Expect = 0.015
 Identities = 27/96 (28%), Positives = 40/96 (41%), Gaps = 4/96 (4%)
 Frame = -1

Query: 641  FTPDQQHAFCQFVTGASRLPTGGLAAL----SPRLTIVRKHPSSGVSALNTSGVTDAADD 474
            F+ + +    QFVTG SR+P  G   L     P++  + K                   +
Sbjct: 922  FSNEMRSRLLQFVTGTSRVPMNGFKELYGSNGPQMFTIEKW---------------GTPN 966

Query: 473  DLPSVMTCANYLKLPPYSTKEVMRKKLLYAILEGRG 366
            + P   TC N L LPPY     ++ KL+ AI   +G
Sbjct: 967  NFPRAHTCFNRLDLPPYEGYLQLKDKLIKAIEGSQG 1002



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>HYD_DROME (P51592) Ubiquitin--protein ligase hyd (EC 6.3.2.-) (Protein|
            hyperplastic discs)
          Length = 2885

 Score = 37.7 bits (86), Expect = 0.032
 Identities = 18/47 (38%), Positives = 27/47 (57%)
 Frame = -1

Query: 521  GVSALNTSGVTDAADDDLPSVMTCANYLKLPPYSTKEVMRKKLLYAI 381
            G   L +  +  A D  LP+  TC + L +P YS+K ++R K+L AI
Sbjct: 2831 GFQPLPSVTIRPADDSHLPTANTCISRLYIPLYSSKSILRSKMLMAI 2877



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>RSP5_YEAST (P39940) E3 ubiquitin--protein ligase RSP5 (EC 6.3.2.-)|
          Length = 809

 Score = 37.0 bits (84), Expect = 0.055
 Identities = 27/95 (28%), Positives = 39/95 (41%)
 Frame = -1

Query: 650 MAEFTPDQQHAFCQFVTGASRLPTGGLAALSPRLTIVRKHPSSGVSALNTSGVTDAADDD 471
           ++E+  +Q+    QF TG SR+P  G   L           S G          +     
Sbjct: 722 VSEWDNEQRARLLQFTTGTSRIPVNGFKDLQG---------SDGPRRFTIEKAGEV--QQ 770

Query: 470 LPSVMTCANYLKLPPYSTKEVMRKKLLYAILEGRG 366
           LP   TC N + LP Y   + M++KL  A+ E  G
Sbjct: 771 LPKSHTCFNRVDLPQYVDYDSMKQKLTLAVEETIG 805



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>EDD1_RAT (Q62671) Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic|
           discs protein homolog) (100 kDa protein) (Fragment)
          Length = 920

 Score = 35.8 bits (81), Expect = 0.12
 Identities = 15/33 (45%), Positives = 24/33 (72%)
 Frame = -1

Query: 479 DDDLPSVMTCANYLKLPPYSTKEVMRKKLLYAI 381
           D  LP+  TC + L +P YS+K+++++KLL AI
Sbjct: 880 DQHLPTANTCISRLYVPLYSSKQILKQKLLLAI 912



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>EDD1_MOUSE (Q80TP3) Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic|
            discs protein homolog)
          Length = 2792

 Score = 35.8 bits (81), Expect = 0.12
 Identities = 15/33 (45%), Positives = 24/33 (72%)
 Frame = -1

Query: 479  DDDLPSVMTCANYLKLPPYSTKEVMRKKLLYAI 381
            D  LP+  TC + L +P YS+K+++++KLL AI
Sbjct: 2752 DQHLPTANTCISRLYVPLYSSKQILKQKLLLAI 2784



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>EDD1_HUMAN (O95071) Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic|
            discs protein homolog) (hHYD) (Progestin-induced protein)
          Length = 2799

 Score = 35.8 bits (81), Expect = 0.12
 Identities = 15/33 (45%), Positives = 24/33 (72%)
 Frame = -1

Query: 479  DDDLPSVMTCANYLKLPPYSTKEVMRKKLLYAI 381
            D  LP+  TC + L +P YS+K+++++KLL AI
Sbjct: 2759 DQHLPTANTCISRLYVPLYSSKQILKQKLLLAI 2791



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>HUTH_STRGR (P24221) Histidine ammonia-lyase (EC 4.3.1.3) (Histidase)|
          Length = 514

 Score = 31.2 bits (69), Expect = 3.0
 Identities = 18/41 (43%), Positives = 21/41 (51%), Gaps = 6/41 (14%)
 Frame = -1

Query: 563 LSPRLTIVRKHPSSGVSALNT------SGVTDAADDDLPSV 459
           L+P L  +R HP  GVSA N       SG+T    DD P V
Sbjct: 238 LAPELHAIRPHPGQGVSADNMSRVLAGSGLTGHHQDDAPRV 278



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>HERC5_HUMAN (Q9UII4) HECT domain and RCC1-like domain-containing protein 5|
            (Cyclin-E-binding protein 1)
          Length = 1024

 Score = 30.8 bits (68), Expect = 4.0
 Identities = 27/109 (24%), Positives = 41/109 (37%), Gaps = 5/109 (4%)
 Frame = -1

Query: 677  PAIINLLEIMAEFTPDQQHAFCQFVTGASRLPTGGLAALSPRLTIVRKHPSSGVSALNTS 498
            P I+   +   + T +++  F  F+TG  RL                      +  LN  
Sbjct: 935  PTIVMFWKAFHKLTLEEKKKFLVFLTGTDRLQ---------------------MKDLNNM 973

Query: 497  GVTDAADD-----DLPSVMTCANYLKLPPYSTKEVMRKKLLYAILEGRG 366
             +T    +     D    +TC + L LP YST E + + L  AI   RG
Sbjct: 974  KITFCCPESWNERDPIRALTCFSVLFLPKYSTMETVEEALQEAINNNRG 1022



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>YL61_SCHPO (Q8TFG9) Hypothetical serine/threonine-rich protein PB15E9.01c|
            precursor
          Length = 943

 Score = 30.0 bits (66), Expect = 6.7
 Identities = 15/54 (27%), Positives = 27/54 (50%)
 Frame = -1

Query: 605  VTGASRLPTGGLAALSPRLTIVRKHPSSGVSALNTSGVTDAADDDLPSVMTCAN 444
            +TG   + TG L  + P  T    + SSG   ++ +  T  +DDD+ +  T ++
Sbjct: 851  ITGNVTITTGDLTTIDPT-TFTSTYLSSGFQTVSNTTATSGSDDDVKTASTSSS 903



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>MBN_DROME (P52302) Protein lethal(3)malignant blood neoplasm 1 (Mbn(83))|
          Length = 653

 Score = 29.6 bits (65), Expect = 8.8
 Identities = 19/65 (29%), Positives = 32/65 (49%), Gaps = 3/65 (4%)
 Frame = -1

Query: 605 VTGASRLPTGGLAA---LSPRLTIVRKHPSSGVSALNTSGVTDAADDDLPSVMTCANYLK 435
           +   ++ P  GL A   L+  +  V +HP++G+  +N SGV+        S  T AN   
Sbjct: 337 IQSVAQHPNAGLNAKVPLASNIQSVAQHPNAGLKNINRSGVS--------SAKTLANTKT 388

Query: 434 LPPYS 420
            PP++
Sbjct: 389 RPPHT 393



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>RB15B_HUMAN (Q8NDT2) Putative RNA-binding protein 15B (RNA-binding motif|
           protein 15B)
          Length = 563

 Score = 29.6 bits (65), Expect = 8.8
 Identities = 13/41 (31%), Positives = 23/41 (56%)
 Frame = +3

Query: 465 GQIVIRSVCYPACIQCTHPTRGVLSNYGKPGTKGSQTTSWK 587
           G +V+++ C+P  +      +GV+S+  K  T GS+ T  K
Sbjct: 397 GLLVLKNSCFPTSMHILEGDQGVISSLLKDHTSGSKLTQLK 437



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>KNIR_DROME (P10734) Zygotic gap protein knirps|
          Length = 429

 Score = 29.6 bits (65), Expect = 8.8
 Identities = 21/64 (32%), Positives = 34/64 (53%)
 Frame = -2

Query: 256 VEVTSRSA*SLKDQSNLLKRRASRAPPTSIRSTFPPIHCK*KGVNIFVVRICSLVGDTMS 77
           +E    S  S +  ++LL   A RA PT+  S+  P+    K  ++  V +CS+ G+T S
Sbjct: 258 LEEDVHSVHSHQSSASLLHPIAIRATPTTPTSS-SPLSFAAKMQSLSPVSVCSIGGETTS 316

Query: 76  YVPI 65
            VP+
Sbjct: 317 VVPV 320


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 94,692,402
Number of Sequences: 219361
Number of extensions: 1963358
Number of successful extensions: 4974
Number of sequences better than 10.0: 59
Number of HSP's better than 10.0 without gapping: 4744
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4936
length of database: 80,573,946
effective HSP length: 108
effective length of database: 56,882,958
effective search space used: 6655306086
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
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