>ERG1_PANGI (O48651) Squalene monooxygenase (EC 1.14.99.7) (Squalene epoxidase)|
           (SE)
          Length = 539

 Score =  154 bits (388), Expect = 1e-37
 Identities = 71/86 (82%), Positives = 78/86 (90%)
 Frame = -2

Query: 464 GVCSNGPIALLSGLNPRPLSLVAHFFAVAIFGVGRLMLPLPSPKRMWTGARLISGACGII 285
           G+CS GPIALLSGLNPRP+SL  HFFAVAI+GVGRL++P PSPKRMW GARLI GA GII
Sbjct: 452 GICSQGPIALLSGLNPRPISLFLHFFAVAIYGVGRLLIPFPSPKRMWLGARLILGASGII 511

Query: 284 FPIIKAEGVRQMFFPATVPAYYRAPP 207
           FPIIK+EG+RQMFFPA VPAYYRAPP
Sbjct: 512 FPIIKSEGLRQMFFPAIVPAYYRAPP 537

>ERG12_ARATH (O65402) Squalene monooxygenase 1,2 (EC 1.14.99.7) (Squalene|
           epoxidase 1,2) (SE 1,2)
          Length = 517

 Score = 84.7 bits (208), Expect = 1e-16
 Identities = 39/84 (46%), Positives = 56/84 (66%)
 Frame = -2

Query: 464 GVCSNGPIALLSGLNPRPLSLVAHFFAVAIFGVGRLMLPLPSPKRMWTGARLISGACGII 285
           G  ++G +ALL G+NPRPLSLV H  A+ +  +G+L+ P PSP R+W   +L   A  ++
Sbjct: 427 GFRTSGMMALLGGMNPRPLSLVYHLCAITLSSIGQLLSPFPSPLRIWHSLKLFGLAMKML 486

Query: 284 FPIIKAEGVRQMFFPATVPAYYRA 213
            P +KAEGV QM FPA   AY+++
Sbjct: 487 VPNLKAEGVSQMLFPANAAAYHKS 510

>ERG11_ARATH (O65404) Squalene monooxygenase 1,1 (EC 1.14.99.7) (Squalene|
           epoxidase 1,1) (SE 1,1)
          Length = 516

 Score = 81.3 bits (199), Expect = 1e-15
 Identities = 37/84 (44%), Positives = 53/84 (63%)
 Frame = -2

Query: 464 GVCSNGPIALLSGLNPRPLSLVAHFFAVAIFGVGRLMLPLPSPKRMWTGARLISGACGII 285
           G  ++G +ALL G+NPRP+SL+ H  A+ +  +G L+ P PSP R+W   RL   A  ++
Sbjct: 426 GFRTSGMMALLGGMNPRPISLIYHLCAITLSSIGHLLSPFPSPLRIWHSLRLFGLAMKML 485

Query: 284 FPIIKAEGVRQMFFPATVPAYYRA 213
            P +KAEGV QM FP    AY ++
Sbjct: 486 VPHLKAEGVSQMLFPVNAAAYSKS 509

>ERG12_BRANA (O65726) Squalene monooxygenase 1,2 (EC 1.14.99.7) (Squalene|
           epoxidase 1,2) (SE 1,2)
          Length = 518

 Score = 76.3 bits (186), Expect = 4e-14
 Identities = 33/84 (39%), Positives = 54/84 (64%)
 Frame = -2

Query: 464 GVCSNGPIALLSGLNPRPLSLVAHFFAVAIFGVGRLMLPLPSPKRMWTGARLISGACGII 285
           G  ++G +AL+ G+NPRPLSL  H F +++  +G+L+ P P+P R+W   RL+  +  ++
Sbjct: 428 GFRTSGLMALIGGMNPRPLSLFYHLFVISLSSIGQLLSPFPTPLRVWHSLRLLDLSLKML 487

Query: 284 FPIIKAEGVRQMFFPATVPAYYRA 213
            P +KAEG+ QM  P    AY ++
Sbjct: 488 VPHLKAEGIGQMLSPTNAAAYRKS 511

>ERG13_ARATH (O65403) Squalene monooxygenase 2 (EC 1.14.99.7) (Squalene|
           epoxidase 2) (SE 2)
          Length = 516

 Score = 65.5 bits (158), Expect = 7e-11
 Identities = 28/80 (35%), Positives = 46/80 (57%)
 Frame = -2

Query: 455 SNGPIALLSGLNPRPLSLVAHFFAVAIFGVGRLMLPLPSPKRMWTGARLISGACGIIFPI 276
           + G + +L G+NP PL+LV H  A+ +  +G L+ P PSP+R W   R+++ A  ++   
Sbjct: 429 TRGLMTILGGMNPHPLTLVLHLVAITLTSMGHLLSPFPSPRRFWHSLRILAWALQMLGAH 488

Query: 275 IKAEGVRQMFFPATVPAYYR 216
           +  EG ++M  P    AY R
Sbjct: 489 LVDEGFKEMLIPTNAAAYRR 508

>ERG11_BRANA (O65727) Squalene monooxygenase 1,1 (EC 1.14.99.7) (Squalene|
           epoxidase 1,1) (SE 1,1)
          Length = 506

 Score = 63.5 bits (153), Expect = 3e-10
 Identities = 33/84 (39%), Positives = 46/84 (54%)
 Frame = -2

Query: 464 GVCSNGPIALLSGLNPRPLSLVAHFFAVAIFGVGRLMLPLPSPKRMWTGARLISGACGII 285
           G  ++G +ALL G+NPRPLSL+ H   + +  +G+L+ P PSP  +W   RL        
Sbjct: 427 GFRTSGMMALLGGMNPRPLSLIFHLCGITLSSIGQLLSPFPSPLGIWHSLRLFG------ 480

Query: 284 FPIIKAEGVRQMFFPATVPAYYRA 213
                AEGV QM  PA   AY ++
Sbjct: 481 -----AEGVSQMLSPAYAAAYRKS 499

>ERG1_HUMAN (Q14534) Squalene monooxygenase (EC 1.14.99.7) (Squalene epoxidase)|
           (SE)
          Length = 574

 Score = 58.2 bits (139), Expect = 1e-08
 Identities = 29/70 (41%), Positives = 43/70 (61%), Gaps = 3/70 (4%)
 Frame = -2

Query: 464 GVCSNGPIALLSGLNPRPLSLVAHFFAVAIFGVGRLMLPLP---SPKRMWTGARLISGAC 294
           G C  GP+ LLS L+P PL+L+ HFFAVAI+ V       P    P+ + + + ++  AC
Sbjct: 499 GECVAGPVGLLSVLSPNPLALIGHFFAVAIYAVYFCFKSEPWITKPRALLSSSAVLYKAC 558

Query: 293 GIIFPIIKAE 264
            +IFP+I +E
Sbjct: 559 SVIFPLIYSE 568

>ERG1_RAT (P52020) Squalene monooxygenase (EC 1.14.99.7) (Squalene epoxidase)|
           (SE)
          Length = 573

 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 27/70 (38%), Positives = 41/70 (58%), Gaps = 3/70 (4%)
 Frame = -2

Query: 464 GVCSNGPIALLSGLNPRPLSLVAHFFAVAIFGVGRLMLPLP---SPKRMWTGARLISGAC 294
           G C  GP+ LLS L+P PL L+ HFF+VA++         P    P+ +++   ++  AC
Sbjct: 498 GECLTGPVGLLSILSPDPLLLIRHFFSVAVYATYFCFKSEPWATKPRALFSSGAILYKAC 557

Query: 293 GIIFPIIKAE 264
            IIFP+I +E
Sbjct: 558 SIIFPLIYSE 567

>ERG1_MOUSE (P52019) Squalene monooxygenase (EC 1.14.99.7) (Squalene epoxidase)|
           (SE)
          Length = 572

 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 27/70 (38%), Positives = 41/70 (58%), Gaps = 3/70 (4%)
 Frame = -2

Query: 464 GVCSNGPIALLSGLNPRPLSLVAHFFAVAIFGVGRLMLPLP---SPKRMWTGARLISGAC 294
           G C  GP+ LLS L+P PL L+ HFF+VAI+         P    P+ +++   ++  AC
Sbjct: 497 GECVTGPVGLLSILSPHPLVLIRHFFSVAIYATYFCFKSEPWATKPRALFSSGAVLYKAC 556

Query: 293 GIIFPIIKAE 264
            I+FP+I +E
Sbjct: 557 SILFPLIYSE 566

>ERG1_SCHPO (Q9C1W3) Probable squalene monooxygenase (EC 1.14.99.7) (Squalene|
           epoxidase) (SE)
          Length = 457

 Score = 45.1 bits (105), Expect = 9e-05
 Identities = 25/70 (35%), Positives = 38/70 (54%), Gaps = 3/70 (4%)
 Frame = -2

Query: 464 GVCSNGPIALLSGLNPRPLSLVAHFFAVAIFGVGRLMLPLPS---PKRMWTGARLISGAC 294
           G C  GPI LL GL+  P  L+ HF+AV ++G+ + +L  P+   P R+     +   A 
Sbjct: 385 GNCVEGPIRLLGGLDHSPSHLIGHFYAVCLYGIYQYVLSGPALLMPVRIIESLLIFLQAS 444

Query: 293 GIIFPIIKAE 264
            +I P I +E
Sbjct: 445 LVIIPYILSE 454

>ERG1_CANAL (Q92206) Squalene monooxygenase (EC 1.14.99.7) (Squalene epoxidase)|
           (SE)
          Length = 496

 Score = 42.7 bits (99), Expect = 5e-04
 Identities = 19/33 (57%), Positives = 23/33 (69%)
 Frame = -2

Query: 464 GVCSNGPIALLSGLNPRPLSLVAHFFAVAIFGV 366
           G C NGPI LLSG+ P P+ L  HFF+VA + V
Sbjct: 424 GECVNGPIGLLSGMLPFPMLLFNHFFSVAFYSV 456

>ERG1_YEAST (P32476) Squalene monooxygenase (EC 1.14.99.7) (Squalene epoxidase)|
           (SE)
          Length = 496

 Score = 36.6 bits (83), Expect = 0.033
 Identities = 16/33 (48%), Positives = 21/33 (63%)
 Frame = -2

Query: 464 GVCSNGPIALLSGLNPRPLSLVAHFFAVAIFGV 366
           G C N P+  LSG+ P+PL L   FFAVA + +
Sbjct: 424 GDCVNKPVEFLSGVLPKPLQLTRVFFAVAFYTI 456

>ERG1_CANGA (O13306) Squalene monooxygenase (EC 1.14.99.7) (Squalene epoxidase)|
           (SE)
          Length = 489

 Score = 35.8 bits (81), Expect = 0.056
 Identities = 16/33 (48%), Positives = 22/33 (66%)
 Frame = -2

Query: 464 GVCSNGPIALLSGLNPRPLSLVAHFFAVAIFGV 366
           G C N P+A L+G+ P+PL L   FFAVA + +
Sbjct: 417 GDCVNLPVAFLAGVLPKPLLLTRVFFAVAFYTI 449

>HR4_DROME (Q9W539) Hormone receptor 4 (dHR4)|
          Length = 1518

 Score = 32.0 bits (71), Expect = 0.81
 Identities = 27/94 (28%), Positives = 41/94 (43%), Gaps = 2/94 (2%)
 Frame = +1

Query: 190 LQNSASGGAR*YAGTVAGKNICLTPSALIIGKM--IPHAPEINLAPVHIRLGEGRGSISR 363
           L  SA G A   A  VA + +    +A I G    +   P  NL PV +  G G GS+  
Sbjct: 626 LMQSAGGAAAAAAAAVAAQRMVCFSNARINGVKPEVIGGPLGNLRPVGVGGGNGSGSVQC 685

Query: 364 PTPKIATAKKCATKLNGRGLRPESRAMGPFEQTP 465
           P+P  +++   +       L P++ +  P   TP
Sbjct: 686 PSPHPSSSSSSSQ------LSPQTPSQTPPRGTP 713

>DSBB_RALSO (Q8XZM2) Disulfide bond formation protein B (Disulfide|
           oxidoreductase)
          Length = 159

 Score = 30.0 bits (66), Expect = 3.1
 Identities = 20/50 (40%), Positives = 27/50 (54%), Gaps = 1/50 (2%)
 Frame = -2

Query: 434 LSGLNPRPLSLVAHFFAVAIFGVGRLMLPLPSPKRM-WTGARLISGACGI 288
           + GL P PL ++  F  V I GV  L+  L S  R+ W G  ++SG  GI
Sbjct: 29  VEGLQPCPLCVLQRFAFVGI-GVFSLLAALSSATRLLWHGLGMLSGLGGI 77

>ERG1_ASHGO (Q75F69) Squalene monooxygenase (EC 1.14.99.7) (Squalene epoxidase)|
           (SE)
          Length = 497

 Score = 29.6 bits (65), Expect = 4.0
 Identities = 20/61 (32%), Positives = 29/61 (47%), Gaps = 3/61 (4%)
 Frame = -2

Query: 446 PIALLSGLNPRPLSLVAHFFAVAIFGV---GRLMLPLPSPKRMWTGARLISGACGIIFPI 276
           PI+ LSG+ P P  L   FF VA++ V    R   PL     ++ G  +I  A  +  P 
Sbjct: 431 PISFLSGVLPSPYLLTKVFFTVALYSVLINFRGRTPLGFLLAIYEGFAIIFTAAKVFTPF 490

Query: 275 I 273
           +
Sbjct: 491 L 491

>RL16_MYCHJ (Q4AAE7) 50S ribosomal protein L16|
          Length = 136

 Score = 29.3 bits (64), Expect = 5.2
 Identities = 21/81 (25%), Positives = 37/81 (45%), Gaps = 4/81 (4%)
 Frame = +1

Query: 202 ASGGAR*YAGTVAGKNICLTP----SALIIGKMIPHAPEINLAPVHIRLGEGRGSISRPT 369
           A+G A   A  +    I +T        +I ++ PH   +   P+ +R+G G+GS+ R  
Sbjct: 37  ATGSAWVSAAQIEAARIAITRRMGREGQVIIRVFPHLA-LTSKPIGVRMGSGKGSVDR-- 93

Query: 370 PKIATAKKCATKLNGRGLRPE 432
             +A  K+       RG++ E
Sbjct: 94  -WVAVVKRNTILFEVRGVKDE 113

>RL16_MYCH7 (Q4A8H8) 50S ribosomal protein L16|
          Length = 136

 Score = 29.3 bits (64), Expect = 5.2
 Identities = 21/81 (25%), Positives = 37/81 (45%), Gaps = 4/81 (4%)
 Frame = +1

Query: 202 ASGGAR*YAGTVAGKNICLTP----SALIIGKMIPHAPEINLAPVHIRLGEGRGSISRPT 369
           A+G A   A  +    I +T        +I ++ PH   +   P+ +R+G G+GS+ R  
Sbjct: 37  ATGSAWVSAAQIEAARIAITRRMGREGQVIIRVFPHLA-LTSKPIGVRMGSGKGSVDR-- 93

Query: 370 PKIATAKKCATKLNGRGLRPE 432
             +A  K+       RG++ E
Sbjct: 94  -WVAVVKRNTILFEVRGVKDE 113

>RL16_MYCH2 (Q601K7) 50S ribosomal protein L16|
          Length = 136

 Score = 29.3 bits (64), Expect = 5.2
 Identities = 21/81 (25%), Positives = 37/81 (45%), Gaps = 4/81 (4%)
 Frame = +1

Query: 202 ASGGAR*YAGTVAGKNICLTP----SALIIGKMIPHAPEINLAPVHIRLGEGRGSISRPT 369
           A+G A   A  +    I +T        +I ++ PH   +   P+ +R+G G+GS+ R  
Sbjct: 37  ATGSAWVSAAQIEAARIAITRRMGREGQVIIRVFPHLA-LTSKPIGVRMGSGKGSVDR-- 93

Query: 370 PKIATAKKCATKLNGRGLRPE 432
             +A  K+       RG++ E
Sbjct: 94  -WVAVVKRNTILFEVRGVKDE 113


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 70,317,342
Number of Sequences: 219361
Number of extensions: 1487942
Number of successful extensions: 3903
Number of sequences better than 10.0: 19
Number of HSP's better than 10.0 without gapping: 3802
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3898
length of database: 80,573,946
effective HSP length: 102
effective length of database: 58,199,124
effective search space used: 3026354448
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)