>U2AF2_DROME (Q24562) Splicing factor U2AF 50 kDa subunit (U2 auxiliary factor|
           50 kDa subunit) (U2 snRNP auxiliary factor large
           subunit)
          Length = 416

 Score = 88.2 bits (217), Expect = 2e-17
 Identities = 57/158 (36%), Positives = 82/158 (51%)
 Frame = -1

Query: 627 DLNVTDIACAALNGIKMGDKTLTVRRANQGSAQPRPEQENIXXXXXXXXXXXXXXXXVGA 448
           DL++TD + A LNG+++GDK L V+RA+ G A+      N                  G 
Sbjct: 257 DLSITDQSIAGLNGMQLGDKKLIVQRASVG-AKNAQNAANTTQSVMLQVPGLSNVVTSGP 315

Query: 447 LPTKVVCLTQVVTADELKXXXXXXXXXXXMRLEAGKYGNLVKVVIPRPHLSGEPVSGVGK 268
            PT+V+CL  +VT DEL+           ++ E  KYG +  V IPRP + G  V G GK
Sbjct: 316 -PTEVLCLLNMVTPDELRDEEEYEDILEDIKEECTKYGVVRSVEIPRP-IEGVEVPGCGK 373

Query: 267 VFLEYADVDGSTKAKTAMHGRKFGGNPVVAVFYPENKF 154
           VF+E+  V    KA+ A+ GRKF    VV  ++  +K+
Sbjct: 374 VFVEFNSVLDCQKAQQALTGRKFSDRVVVTSYFDPDKY 411

>U2AF2_CAEEL (P90978) Splicing factor U2AF 65 kDa subunit (U2 auxiliary factor|
           65 kDa subunit) (U2 snRNP auxiliary factor large
           subunit) (U2AF65)
          Length = 496

 Score = 87.0 bits (214), Expect = 5e-17
 Identities = 53/158 (33%), Positives = 76/158 (48%)
 Frame = -1

Query: 627 DLNVTDIACAALNGIKMGDKTLTVRRANQGSAQPRPEQENIXXXXXXXXXXXXXXXXVGA 448
           D  +TD A A LNG+++GDK L V+ A         ++ N                    
Sbjct: 340 DPTLTDQAIAGLNGMQLGDKQLVVQLACANQ-----QRHNTNLPNSASAIAGIDLSQGAG 394

Query: 447 LPTKVVCLTQVVTADELKXXXXXXXXXXXMRLEAGKYGNLVKVVIPRPHLSGEPVSGVGK 268
             T+++CL  +VT DELK           +R E  KYG +  + IPRP+    PV GVGK
Sbjct: 395 RATEILCLMNMVTEDELKADDEYEEILEDVRDECSKYGIVRSLEIPRPY-EDHPVPGVGK 453

Query: 267 VFLEYADVDGSTKAKTAMHGRKFGGNPVVAVFYPENKF 154
           VF+E+A      +A+ A+ GRKF    VV  +Y  +K+
Sbjct: 454 VFVEFASTSDCQRAQAALTGRKFANRTVVTSYYDVDKY 491

>U2AF2_CAEBR (P90727) Splicing factor U2AF 65 kDa subunit (U2 auxiliary factor|
           65 kDa subunit) (U2 snRNP auxiliary factor large
           subunit) (U2AF65)
          Length = 488

 Score = 85.1 bits (209), Expect = 2e-16
 Identities = 52/158 (32%), Positives = 75/158 (47%)
 Frame = -1

Query: 627 DLNVTDIACAALNGIKMGDKTLTVRRANQGSAQPRPEQENIXXXXXXXXXXXXXXXXVGA 448
           D  +TD A A LNG+++GDK L V+ A     +      N                    
Sbjct: 331 DPTLTDQAIAGLNGMQLGDKQLVVQLACANQTRHNTHLPN-----SASAIAGIDLSQGAG 385

Query: 447 LPTKVVCLTQVVTADELKXXXXXXXXXXXMRLEAGKYGNLVKVVIPRPHLSGEPVSGVGK 268
             T+++CL  +VT DEL+           +R E  KYG +  + IPRP+    PV GVGK
Sbjct: 386 RATEILCLMNMVTEDELRSDEDYEEILEDVREECSKYGIVRSLEIPRPY-DDHPVPGVGK 444

Query: 267 VFLEYADVDGSTKAKTAMHGRKFGGNPVVAVFYPENKF 154
           VF+E+A      +A+ A+ GRKF    VV  +Y  +K+
Sbjct: 445 VFVEFATTSDCQRAQAALTGRKFANRTVVTSYYDVDKY 482

>U2AF2_MOUSE (P26369) Splicing factor U2AF 65 kDa subunit (U2 auxiliary factor|
           65 kDa subunit) (U2 snRNP auxiliary factor large
           subunit)
          Length = 475

 Score = 83.6 bits (205), Expect = 5e-16
 Identities = 54/156 (34%), Positives = 75/156 (48%), Gaps = 4/156 (2%)
 Frame = -1

Query: 627 DLNVTDIACAALNGIKMGDKTLTVRRANQGSAQPR----PEQENIXXXXXXXXXXXXXXX 460
           D+NVTD A A LNG+++GDK L V+RA+ G+        P   N                
Sbjct: 309 DINVTDQAIAGLNGMQLGDKKLLVQRASVGAKNATLVSLPSTINQTPVTLQVPGLMSSQV 368

Query: 459 XVGALPTKVVCLTQVVTADELKXXXXXXXXXXXMRLEAGKYGNLVKVVIPRPHLSGEPVS 280
            +G  PT+V+CL  +V  +EL            +R E  KYG +  + IPRP + G  V 
Sbjct: 369 QMGGHPTEVLCLMNMVLPEELLDDEEYEEIVEDVRDECSKYGLVKSIEIPRP-VDGVEVP 427

Query: 279 GVGKVFLEYADVDGSTKAKTAMHGRKFGGNPVVAVF 172
           G GK+F+E+  V    KA   + GRKF    VV  +
Sbjct: 428 GCGKIFVEFTSVFDCQKAMQGLTGRKFANRVVVTKY 463

>U2AF2_HUMAN (P26368) Splicing factor U2AF 65 kDa subunit (U2 auxiliary factor|
           65 kDa subunit) (U2 snRNP auxiliary factor large
           subunit) (hU2AF(65))
          Length = 475

 Score = 83.6 bits (205), Expect = 5e-16
 Identities = 54/156 (34%), Positives = 75/156 (48%), Gaps = 4/156 (2%)
 Frame = -1

Query: 627 DLNVTDIACAALNGIKMGDKTLTVRRANQGSAQPR----PEQENIXXXXXXXXXXXXXXX 460
           D+NVTD A A LNG+++GDK L V+RA+ G+        P   N                
Sbjct: 309 DINVTDQAIAGLNGMQLGDKKLLVQRASVGAKNATLVSPPSTINQTPVTLQVPGLMSSQV 368

Query: 459 XVGALPTKVVCLTQVVTADELKXXXXXXXXXXXMRLEAGKYGNLVKVVIPRPHLSGEPVS 280
            +G  PT+V+CL  +V  +EL            +R E  KYG +  + IPRP + G  V 
Sbjct: 369 QMGGHPTEVLCLMNMVLPEELLDDEEYEEIVEDVRDECSKYGLVKSIEIPRP-VDGVEVP 427

Query: 279 GVGKVFLEYADVDGSTKAKTAMHGRKFGGNPVVAVF 172
           G GK+F+E+  V    KA   + GRKF    VV  +
Sbjct: 428 GCGKIFVEFTSVFDCQKAMQGLTGRKFANRVVVTKY 463

>U2AF2_SCHPO (P36629) Splicing factor U2AF 59 kDa subunit (U2 auxiliary factor|
           59 kDa subunit) (U2 snRNP auxiliary factor large
           subunit) (U2AF59)
          Length = 517

 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 29/97 (29%), Positives = 48/97 (49%)
 Frame = -1

Query: 450 ALPTKVVCLTQVVTADELKXXXXXXXXXXXMRLEAGKYGNLVKVVIPRPHLSGEPVSGVG 271
           ++PT+V+ L  ++T DE+            ++ +   YG L+ + IPR   +     G G
Sbjct: 414 SIPTRVLQLHNLITGDEIMDVQEYEDIYESVKTQFSNYGPLIDIKIPRSIGTRNSGLGTG 473

Query: 270 KVFLEYADVDGSTKAKTAMHGRKFGGNPVVAVFYPEN 160
           KVF+ Y+D+  +  A   M G KF    +V  FY E+
Sbjct: 474 KVFVRYSDIRSAEVAMEEMKGCKFNDRTIVIAFYGED 510

>UHMK1_RAT (Q63285) Serine/threonine-protein kinase Kist (EC 2.7.11.1) (Kinase|
           interacting with stathmin) (U2AF homology motif kinase
           1) (PAM COOH-terminal interactor protein 2) (P-CIP2)
          Length = 419

 Score = 53.9 bits (128), Expect = 4e-07
 Identities = 33/94 (35%), Positives = 49/94 (52%)
 Frame = -1

Query: 447 LPTKVVCLTQVVTADELKXXXXXXXXXXXMRLEAGKYGNLVKVVIPRPHLSGEPVSGVGK 268
           LPT V+ L  V+  D L+           ++ E  KYG +V +++P+ +       G G+
Sbjct: 318 LPTPVLRLLNVLDDDYLENEDEYEDVVEDVKEECQKYGPVVSLLVPKEN------PGRGQ 371

Query: 267 VFLEYADVDGSTKAKTAMHGRKFGGNPVVAVFYP 166
           VF+EYA+   S  A+  + GR F G  VVA FYP
Sbjct: 372 VFVEYANAGDSKAAQKLLTGRMFDGKFVVATFYP 405

>UHMK1_MOUSE (P97343) Serine/threonine-protein kinase Kist (EC 2.7.11.1) (Kinase|
           interacting with stathmin) (U2AF homology motif kinase
           1)
          Length = 419

 Score = 53.9 bits (128), Expect = 4e-07
 Identities = 33/94 (35%), Positives = 49/94 (52%)
 Frame = -1

Query: 447 LPTKVVCLTQVVTADELKXXXXXXXXXXXMRLEAGKYGNLVKVVIPRPHLSGEPVSGVGK 268
           LPT V+ L  V+  D L+           ++ E  KYG +V +++P+ +       G G+
Sbjct: 318 LPTPVLRLLNVLDDDYLENEDEYEDVVEDVKEECQKYGPVVSLLVPKEN------PGRGQ 371

Query: 267 VFLEYADVDGSTKAKTAMHGRKFGGNPVVAVFYP 166
           VF+EYA+   S  A+  + GR F G  VVA FYP
Sbjct: 372 VFVEYANAGDSKAAQKLLTGRMFDGKFVVATFYP 405

>UHMK1_HUMAN (Q8TAS1) Serine/threonine-protein kinase Kist (EC 2.7.11.1) (Kinase|
           interacting with stathmin) (U2AF homology motif kinase
           1)
          Length = 419

 Score = 53.9 bits (128), Expect = 4e-07
 Identities = 33/94 (35%), Positives = 49/94 (52%)
 Frame = -1

Query: 447 LPTKVVCLTQVVTADELKXXXXXXXXXXXMRLEAGKYGNLVKVVIPRPHLSGEPVSGVGK 268
           LPT V+ L  V+  D L+           ++ E  KYG +V +++P+ +       G G+
Sbjct: 318 LPTPVLRLLNVLDDDYLENEEEYEDVVEDVKEECQKYGPVVSLLVPKEN------PGRGQ 371

Query: 267 VFLEYADVDGSTKAKTAMHGRKFGGNPVVAVFYP 166
           VF+EYA+   S  A+  + GR F G  VVA FYP
Sbjct: 372 VFVEYANAGDSKAAQKLLTGRMFDGKFVVATFYP 405

>SPF45_MOUSE (Q8JZX4) Splicing factor 45 (45 kDa splicing factor) (RNA-binding|
           motif protein 17)
          Length = 405

 Score = 50.1 bits (118), Expect = 6e-06
 Identities = 35/97 (36%), Positives = 48/97 (49%)
 Frame = -1

Query: 444 PTKVVCLTQVVTADELKXXXXXXXXXXXMRLEAGKYGNLVKVVIPRPHLSGEPVSGVGKV 265
           PTKVV L  +V A E+             + E  KYG + K VI    + G P     ++
Sbjct: 307 PTKVVLLRNMVGAGEVDEDLEVET-----KEECEKYGKVGKCVIFE--IPGAPDDEAVRI 359

Query: 264 FLEYADVDGSTKAKTAMHGRKFGGNPVVAVFYPENKF 154
           FLE+  V+ + KA   ++GR FGG  V A FY  +KF
Sbjct: 360 FLEFERVESAIKAVVDLNGRYFGGRVVKACFYNLDKF 396

>SPF45_HUMAN (Q96I25) Splicing factor 45 (45 kDa splicing factor) (RNA-binding|
           motif protein 17)
          Length = 401

 Score = 50.1 bits (118), Expect = 6e-06
 Identities = 35/97 (36%), Positives = 48/97 (49%)
 Frame = -1

Query: 444 PTKVVCLTQVVTADELKXXXXXXXXXXXMRLEAGKYGNLVKVVIPRPHLSGEPVSGVGKV 265
           PTKVV L  +V A E+             + E  KYG + K VI    + G P     ++
Sbjct: 303 PTKVVLLRNMVGAGEVDEDLEVET-----KEECEKYGKVGKCVIFE--IPGAPDDEAVRI 355

Query: 264 FLEYADVDGSTKAKTAMHGRKFGGNPVVAVFYPENKF 154
           FLE+  V+ + KA   ++GR FGG  V A FY  +KF
Sbjct: 356 FLEFERVESAIKAVVDLNGRYFGGRVVKACFYNLDKF 392

>DR111_ARATH (P42698) DNA-damage-repair/toleration protein DRT111, chloroplast|
           precursor
          Length = 387

 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 25/66 (37%), Positives = 37/66 (56%)
 Frame = -1

Query: 351 EAGKYGNLVKVVIPRPHLSGEPVSGVGKVFLEYADVDGSTKAKTAMHGRKFGGNPVVAVF 172
           E GKYG + +V+I        PV    ++F++++  + +TKA   + GR FGG  V A F
Sbjct: 307 ECGKYGTVTRVLIFEITEPNFPVHEAVRIFVQFSRPEETTKALVDLDGRYFGGRTVRATF 366

Query: 171 YPENKF 154
           Y E KF
Sbjct: 367 YDEEKF 372

>RSD1_SCHPO (O13845) RNA-binding protein rsd1|
          Length = 604

 Score = 37.4 bits (85), Expect = 0.043
 Identities = 19/63 (30%), Positives = 32/63 (50%)
 Frame = -1

Query: 342 KYGNLVKVVIPRPHLSGEPVSGVGKVFLEYADVDGSTKAKTAMHGRKFGGNPVVAVFYPE 163
           KYG +V + +    L        G++F+++ + D + KA T +H R FGG  + A   PE
Sbjct: 540 KYGKVVHIAVVPNEL--------GQIFVKFENADFAEKAITGLHQRWFGGRTIKASILPE 591

Query: 162 NKF 154
             +
Sbjct: 592 TDY 594

>PUF68_DROME (Q8T6B9) Poly U-binding splicing factor half pint (68 kDa poly|
           U-binding splicing factor) (Protein half pint) (PUF60
           homolog)
          Length = 637

 Score = 34.7 bits (78), Expect = 0.28
 Identities = 20/70 (28%), Positives = 35/70 (50%), Gaps = 4/70 (5%)
 Frame = -1

Query: 351 EAGKYGNLVKVVI----PRPHLSGEPVSGVGKVFLEYADVDGSTKAKTAMHGRKFGGNPV 184
           E  K+G + +V+I       +   +    + K+F+E++    + + K A+ GR FGG  V
Sbjct: 561 ECSKFGTVSRVIIFNEKQTENEDDDEAEIIVKIFVEFSAGAEAMRGKEALDGRFFGGRRV 620

Query: 183 VAVFYPENKF 154
           VA  Y +  F
Sbjct: 621 VAELYDQGIF 630

>RS2_LEIAM (O43992) 40S ribosomal protein S2|
          Length = 265

 Score = 33.9 bits (76), Expect = 0.47
 Identities = 23/66 (34%), Positives = 34/66 (51%), Gaps = 3/66 (4%)
 Frame = -1

Query: 345 GKYGNLVKVVIPRPHLSGEPVSGVGKVFLEYA---DVDGSTKAKTAMHGRKFGGNPVVAV 175
           GK G++   ++P P  +G   + V K  LE+A   DV  S++ KT  H     GN ++A 
Sbjct: 172 GKCGSVAVRLVPAPRGTGIVAAPVPKKILEFAGVEDVYTSSRGKTRTH-----GNLIMAT 226

Query: 174 FYPENK 157
           FY   K
Sbjct: 227 FYALRK 232

>RNPC2_MOUSE (Q8VH51) RNA-binding region-containing protein 2 (Coactivator of|
           activating protein 1 and estrogen receptors)
           (Coactivator of AP-1 and ERs) (Transcription coactivator
           CAPER)
          Length = 530

 Score = 32.0 bits (71), Expect = 1.8
 Identities = 15/62 (24%), Positives = 29/62 (46%)
 Frame = -1

Query: 351 EAGKYGNLVKVVIPRPHLSGEPVSGVGKVFLEYADVDGSTKAKTAMHGRKFGGNPVVAVF 172
           E  K+G ++ + + +        S  G V+++   +  +  A  A+HGR F G  + A +
Sbjct: 453 ECNKHGGVIHIYVDKN-------SAQGNVYVKCPSIAAAIAAVNALHGRWFAGKMITAAY 505

Query: 171 YP 166
            P
Sbjct: 506 VP 507

>RNPC2_HUMAN (Q14498) RNA-binding region-containing protein 2 (Hepatocellular|
           carcinoma protein 1) (Splicing factor HCC1)
          Length = 530

 Score = 32.0 bits (71), Expect = 1.8
 Identities = 15/62 (24%), Positives = 29/62 (46%)
 Frame = -1

Query: 351 EAGKYGNLVKVVIPRPHLSGEPVSGVGKVFLEYADVDGSTKAKTAMHGRKFGGNPVVAVF 172
           E  K+G ++ + + +        S  G V+++   +  +  A  A+HGR F G  + A +
Sbjct: 453 ECNKHGGVIHIYVDKN-------SAQGNVYVKCPSIAAAIAAVNALHGRWFAGKMITAAY 505

Query: 171 YP 166
            P
Sbjct: 506 VP 507

>SRA31_CAEEL (Q18881) Serpentine receptor class alpha-31 (Protein sra-31)|
          Length = 338

 Score = 31.6 bits (70), Expect = 2.3
 Identities = 19/60 (31%), Positives = 28/60 (46%), Gaps = 1/60 (1%)
 Frame = +1

Query: 70  CKSNELHKTLLALEKRDNLCCRIIVLFSKLVLGV-EDRNNWVSTKFPSMHRRLCFGGAIN 246
           C S E+  TL +     N C  ++++ S + L V   R  W +  FP+  R L F   IN
Sbjct: 7   CTSEEIRLTLTSSFMMGNHCFILLIIISSVFLTVFAIRKLWKNNIFPNCTRTLLFSAIIN 66

>RS2_DICDI (P27685) 40S ribosomal protein S2 (S4) (LLRep3 protein)|
          Length = 265

 Score = 30.4 bits (67), Expect = 5.2
 Identities = 22/66 (33%), Positives = 34/66 (51%), Gaps = 3/66 (4%)
 Frame = -1

Query: 345 GKYGNLVKVVIPRPHLSGEPVSGVGKVFLEYADVDG---STKAKTAMHGRKFGGNPVVAV 175
           GK G++   ++P P  +G   + V K  L+YA VD    S++ KT     +  GN V+A 
Sbjct: 173 GKCGSVAVRLVPAPRGTGIVAARVPKKLLQYAGVDDVYTSSRGKT-----RTMGNFVMAT 227

Query: 174 FYPENK 157
           F+   K
Sbjct: 228 FFAITK 233

>YEEJ_ECOLI (P76347) Hypothetical protein yeeJ|
          Length = 2358

 Score = 30.0 bits (66), Expect = 6.8
 Identities = 14/34 (41%), Positives = 21/34 (61%)
 Frame = -1

Query: 633  VKDLNVTDIACAALNGIKMGDKTLTVRRANQGSA 532
            V + N + IA A L G+  G+KT+T   AN G++
Sbjct: 1199 VSNTNESGIAQATLAGVAFGEKTVTASLANNGAS 1232

>ZN418_HUMAN (Q8TF45) Zinc finger protein 418|
          Length = 676

 Score = 30.0 bits (66), Expect = 6.8
 Identities = 16/36 (44%), Positives = 21/36 (58%)
 Frame = +3

Query: 168 GRRPQQLGFHQISFHASPSLLWWSHQHLHTLRTPFQ 275
           G RP +      SFH S SLL   HQ +HT R+P++
Sbjct: 643 GERPYECSECGKSFHRSSSLL--RHQRVHTERSPYK 676



 Score = 30.0 bits (66), Expect = 6.8
 Identities = 16/39 (41%), Positives = 21/39 (53%)
 Frame = +3

Query: 168 GRRPQQLGFHQISFHASPSLLWWSHQHLHTLRTPFQLQK 284
           G RP + G    SFH S SLL   HQ  HT   P++ ++
Sbjct: 534 GERPYECGECGKSFHQSSSLL--RHQKTHTAERPYECRE 570


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 98,078,688
Number of Sequences: 219361
Number of extensions: 2049901
Number of successful extensions: 4903
Number of sequences better than 10.0: 21
Number of HSP's better than 10.0 without gapping: 4676
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4885
length of database: 80,573,946
effective HSP length: 108
effective length of database: 56,882,958
effective search space used: 6712189044
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)