>XPP1_RAT (O54975) Xaa-Pro aminopeptidase 1 (EC 3.4.11.9) (X-Pro|
           aminopeptidase 1) (X-prolyl aminopeptidase 1, soluble)
           (Cytosolic aminopeptidase P) (Soluble aminopeptidase P)
           (sAmp) (Aminoacylproline aminopeptidase)
          Length = 623

 Score = 84.7 bits (208), Expect = 9e-17
 Identities = 40/89 (44%), Positives = 57/89 (64%), Gaps = 4/89 (4%)
 Frame = -1

Query: 448 FGIRLENVLIVKEADTKFNFGEKGYLSFEHITWAPYQTKLINTALLTPAEIEWVNVYHSD 269
           FGIR+ENV++V  A TK+NF  +G L+FE +T  P QTK+I+   LT  E +W+N YH  
Sbjct: 532 FGIRIENVVLVVPAKTKYNFNNRGSLTFEPLTLVPIQTKMIDVDALTDKECDWLNSYHQT 591

Query: 268 CQKILESYLNVQEK----EWLRKATEPIT 194
           C+ ++   L  Q +    EWL + TEPI+
Sbjct: 592 CRDVIGKELQTQGRQEALEWLLRETEPIS 620

>XPP1_MOUSE (Q6P1B1) Xaa-Pro aminopeptidase 1 (EC 3.4.11.9) (X-Pro|
           aminopeptidase 1) (X-prolyl aminopeptidase 1, soluble)
           (Cytosolic aminopeptidase P) (Soluble aminopeptidase P)
           (sAmp) (Aminoacylproline aminopeptidase)
          Length = 623

 Score = 82.8 bits (203), Expect = 4e-16
 Identities = 39/89 (43%), Positives = 57/89 (64%), Gaps = 4/89 (4%)
 Frame = -1

Query: 448 FGIRLENVLIVKEADTKFNFGEKGYLSFEHITWAPYQTKLINTALLTPAEIEWVNVYHSD 269
           FGIR+ENV++V  A TK+NF  +G L+FE +T  P QTK+I+   LT  E +W+N YH  
Sbjct: 532 FGIRIENVVLVVPAKTKYNFNNRGSLTFEPLTLVPIQTKMIDVNALTDKECDWLNSYHQT 591

Query: 268 CQKILESYLNVQEK----EWLRKATEPIT 194
           C+ ++   L  Q +    EWL + TEP++
Sbjct: 592 CRDVVGKELQSQGRQEALEWLIRETEPVS 620

>XPP1_HUMAN (Q9NQW7) Xaa-Pro aminopeptidase 1 (EC 3.4.11.9) (X-Pro|
           aminopeptidase 1) (X-prolyl aminopeptidase 1, soluble)
           (Cytosolic aminopeptidase P) (Soluble aminopeptidase P)
           (sAmp) (Aminoacylproline aminopeptidase)
          Length = 622

 Score = 79.3 bits (194), Expect = 4e-15
 Identities = 38/89 (42%), Positives = 56/89 (62%), Gaps = 4/89 (4%)
 Frame = -1

Query: 448 FGIRLENVLIVKEADTKFNFGEKGYLSFEHITWAPYQTKLINTALLTPAEIEWVNVYHSD 269
           FGIR+ENV++V    TK+NF  +G L+FE +T  P QTK+I+   LT  E +W+N YH  
Sbjct: 531 FGIRIENVVLVVPVKTKYNFNNRGSLTFEPLTLVPIQTKMIDVDSLTDKECDWLNNYHLT 590

Query: 268 CQKILESYLNVQEK----EWLRKATEPIT 194
           C+ ++   L  Q +    EWL + T+PI+
Sbjct: 591 CRDVIGKELQKQGRQEALEWLIRETQPIS 619

>YAA1_SCHPO (Q09795) Probable peptidase C22G7.01c (EC 3.4.-.-)|
          Length = 598

 Score = 73.2 bits (178), Expect = 3e-13
 Identities = 34/84 (40%), Positives = 53/84 (63%)
 Frame = -1

Query: 448 FGIRLENVLIVKEADTKFNFGEKGYLSFEHITWAPYQTKLINTALLTPAEIEWVNVYHSD 269
           FG R+EN + + E +T+  F  + YL  + +T AP+  KLI+ +LL+P E++++N YHS+
Sbjct: 515 FGYRVENCVYITEVNTENRFAGRTYLGLKDLTLAPHCQKLIDPSLLSPEEVKYLNEYHSE 574

Query: 268 CQKILESYLNVQEKEWLRKATEPI 197
               L   L+V  K+WL K T PI
Sbjct: 575 VYTTLSPMLSVSAKKWLSKHTSPI 598

>XPP2_HUMAN (O43895) Xaa-Pro aminopeptidase 2 precursor (EC 3.4.11.9) (X-Pro|
           aminopeptidase 2) (Membrane-bound aminopeptidase P)
           (Membrane-bound APP) (Membrane-bound AmP) (mAmP)
           (Aminoacylproline aminopeptidase)
          Length = 674

 Score = 63.9 bits (154), Expect = 2e-10
 Identities = 34/90 (37%), Positives = 57/90 (63%), Gaps = 4/90 (4%)
 Frame = -1

Query: 448 FGIRLENVLIVKEADTKFNFGEKGYLSFEHITWAPYQTKLINTALLTPAEIEWVNVYHSD 269
           FGIRLE+V +V EA TK+      YL+FE +++ PY   LI+ +LL+P  ++++N Y+  
Sbjct: 564 FGIRLEDVALVVEAKTKY---PGSYLTFEVVSFVPYDRNLIDVSLLSPEHLQYLNRYYQT 620

Query: 268 CQKILESYLN----VQEKEWLRKATEPITA 191
            ++ +   L     ++E EWL++ TEP+ A
Sbjct: 621 IREKVGPELQRRQLLEEFEWLQQHTEPLAA 650

>XPP2_PIG (Q95333) Xaa-Pro aminopeptidase 2 precursor (EC 3.4.11.9) (X-Pro|
           aminopeptidase 2) (Membrane-bound aminopeptidase P)
           (Membrane-bound APP) (Membrane-bound AmP) (mAmP)
           (Aminoacylproline aminopeptidase)
          Length = 673

 Score = 63.5 bits (153), Expect = 2e-10
 Identities = 34/90 (37%), Positives = 58/90 (64%), Gaps = 4/90 (4%)
 Frame = -1

Query: 448 FGIRLENVLIVKEADTKFNFGEKGYLSFEHITWAPYQTKLINTALLTPAEIEWVNVYHSD 269
           FGIRLE+V +V EA TK+      YL+FE ++  PY  KLI+ +LL+P +++++N Y+  
Sbjct: 563 FGIRLEDVALVVEAKTKY---PGTYLTFEVVSLVPYDRKLIDVSLLSPEQLQYLNRYYQA 619

Query: 268 CQKILESYLN----VQEKEWLRKATEPITA 191
            ++ +   L     ++E  WL++ TEP++A
Sbjct: 620 IREKVGPELQRRGLLEELSWLQRHTEPLSA 649

>XPP_YEAST (Q07825) Putative Xaa-Pro aminopeptidase (EC 3.4.11.9)|
          Length = 749

 Score = 58.2 bits (139), Expect = 9e-09
 Identities = 32/86 (37%), Positives = 50/86 (58%), Gaps = 2/86 (2%)
 Frame = -1

Query: 448 FGIRLENVLIVKEADTKFNFGEKGYLSFEHITWAPYQTKLINTALLTPAEIEWVNVYHSD 269
           +GIR+E+ +++K+A  K NF     L FE++T  PY  KLINT LL   E   +N YH+ 
Sbjct: 669 YGIRIESDMLIKKATEKGNF-----LKFENMTVVPYCRKLINTKLLNEEEKTQINEYHAR 723

Query: 268 CQKILESYLNVQ--EKEWLRKATEPI 197
             + +  +L  Q    +WL++ T P+
Sbjct: 724 VWRTIVHFLQPQSISYKWLKRETSPL 749

>TRI56_MOUSE (Q80VI1) Tripartite motif protein 56|
          Length = 734

 Score = 33.1 bits (74), Expect = 0.32
 Identities = 24/70 (34%), Positives = 31/70 (44%), Gaps = 1/70 (1%)
 Frame = -3

Query: 332 TYKHRLVDPCGDRMGKRVPLRLPENLGVLPKCSGEGMAEEGH*TYNCEQLSQLLHGYCCC 153
           T+KHR+VD  G R G              P+  GE +       + C+  SQLL   C  
Sbjct: 141 THKHRVVDLVGYRAGWYDEEARERQASQCPQHPGEALC------FLCQPCSQLLCKDCRL 194

Query: 152 APNIDR-CLP 126
            P+ID  CLP
Sbjct: 195 GPHIDHPCLP 204

>AP180_RAT (Q05140) Clathrin coat assembly protein AP180 (Clathrin|
           coat-associated protein AP180) (91 kDa
           synaptosomal-associated protein)
          Length = 915

 Score = 31.2 bits (69), Expect = 1.2
 Identities = 15/32 (46%), Positives = 19/32 (59%)
 Frame = +1

Query: 214 SSAIPSPEHLGKTPRFSGSRSGTRLPIRSPQG 309
           SSA PS + L   P FSG+R+G   P+  P G
Sbjct: 341 SSAKPSSDLLDLQPDFSGARAGAAAPVPPPTG 372

>AP180_MOUSE (Q61548) Clathrin coat assembly protein AP180 (Clathrin|
           coat-associated protein AP180) (91 kDa
           synaptosomal-associated protein) (Phosphoprotein F1-20)
          Length = 901

 Score = 28.9 bits (63), Expect = 6.0
 Identities = 14/32 (43%), Positives = 18/32 (56%)
 Frame = +1

Query: 214 SSAIPSPEHLGKTPRFSGSRSGTRLPIRSPQG 309
           SSA PS + L   P FSG+ +G   P+  P G
Sbjct: 341 SSAKPSSDLLDLQPDFSGAAAGAAAPVVPPSG 372

>MUTL_LISIN (Q92BV2) DNA mismatch repair protein mutL|
          Length = 603

 Score = 28.9 bits (63), Expect = 6.0
 Identities = 22/83 (26%), Positives = 40/83 (48%), Gaps = 16/83 (19%)
 Frame = -1

Query: 394 NFGEKGYLSFEHITWAPYQ------TKLINTALLTPA----EIEWVNVYHSDCQKILES- 248
           NFG+  ++   H TW P         ++I+ AL  P+    ++         C+K +++ 
Sbjct: 497 NFGQNSFIIRAHPTWFPKDQEEEMLREIIDEALSAPSISIHKLREDTAIMMSCKKSIKAN 556

Query: 247 -YLNVQEKE----WLRKATEPIT 194
            YL +Q+ E     LR+A++P T
Sbjct: 557 HYLTMQDMEALLDTLREASDPFT 579

>IL2RG_BOVIN (Q95118) Cytokine receptor common gamma chain precursor (Gamma-C)|
           (Interleukin-2 receptor gamma chain) (IL-2R gamma chain)
           (p64) (CD132 antigen)
          Length = 379

 Score = 28.5 bits (62), Expect = 7.9
 Identities = 14/52 (26%), Positives = 24/52 (46%)
 Frame = -1

Query: 358 ITWAPYQTKLINTALLTPAEIEWVNVYHSDCQKILESYLNVQEKEWLRKATE 203
           I WAP    L N +     E+ W N Y   C + L  Y + +++ W  ++ +
Sbjct: 160 IPWAPENLTLRNLSEFQ-LELSWSNRYLDHCLEHLVQYRSDRDRSWTEQSVD 210

>MUTL_LISMO (Q8Y788) DNA mismatch repair protein mutL|
          Length = 601

 Score = 28.5 bits (62), Expect = 7.9
 Identities = 22/83 (26%), Positives = 39/83 (46%), Gaps = 16/83 (19%)
 Frame = -1

Query: 394 NFGEKGYLSFEHITWAPYQ------TKLINTALLTPA----EIEWVNVYHSDCQKILES- 248
           NFG+  ++   H TW P         ++I+ AL  P+    ++         C+K +++ 
Sbjct: 495 NFGQNSFIIRAHPTWFPKDQEEEMLREIIDEALSAPSISIHKLREDTAIMMSCKKSIKAN 554

Query: 247 -YLNVQEKE----WLRKATEPIT 194
            YL  Q+ E     LR+A++P T
Sbjct: 555 HYLTTQDMEALLDTLREASDPFT 577

>SYA_DEHE1 (Q3ZAE4) Alanyl-tRNA synthetase (EC 6.1.1.7) (Alanine--tRNA ligase)|
           (AlaRS)
          Length = 871

 Score = 28.5 bits (62), Expect = 7.9
 Identities = 19/47 (40%), Positives = 22/47 (46%), Gaps = 1/47 (2%)
 Frame = -1

Query: 394 NFGEKGYLSFEHITWA-PYQTKLINTALLTPAEIEWVNVYHSDCQKI 257
           NF    Y   E I WA  Y T+ +N     PAE  WV VY  D + I
Sbjct: 90  NFSIGNYFKKEAIAWAWEYVTQRLNI----PAEKLWVTVYLDDDEAI 132

>MUTL_LISMF (Q71ZR6) DNA mismatch repair protein mutL|
          Length = 603

 Score = 28.5 bits (62), Expect = 7.9
 Identities = 22/83 (26%), Positives = 39/83 (46%), Gaps = 16/83 (19%)
 Frame = -1

Query: 394 NFGEKGYLSFEHITWAPYQ------TKLINTALLTPA----EIEWVNVYHSDCQKILES- 248
           NFG+  ++   H TW P         ++I+ AL  P+    ++         C+K +++ 
Sbjct: 497 NFGQNSFIIRAHPTWFPKDQEEEMLREIIDEALSAPSISIHKLREDTAIMMSCKKSIKAN 556

Query: 247 -YLNVQEKE----WLRKATEPIT 194
            YL  Q+ E     LR+A++P T
Sbjct: 557 HYLTTQDMEALLDTLREASDPFT 579


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 67,782,324
Number of Sequences: 219361
Number of extensions: 1428427
Number of successful extensions: 3113
Number of sequences better than 10.0: 15
Number of HSP's better than 10.0 without gapping: 3019
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3103
length of database: 80,573,946
effective HSP length: 102
effective length of database: 58,199,124
effective search space used: 2677159704
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)