ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | rbah61g02 |
|---|---|
| Clone Library Name | barley_pub |
>BAK1_ARATH (Q94F62) BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1| precursor (EC 2.7.11.1) (BRI1-associated receptor kinase 1) (Somatic embryogenesis receptor-like kinase 3) Length = 615 Score = 69.3 bits (168), Expect = 8e-12 Identities = 49/122 (40%), Positives = 66/122 (54%), Gaps = 5/122 (4%) Frame = -2 Query: 573 ALRGTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNAD-PNAANSSQSYYPSW 397 A+RGTIG+IAPE +S G S K+DV+ +G++LLE+ G+R D AN W Sbjct: 451 AVRGTIGHIAPEYLST--GKSSEKTDVFGYGVMLLELITGQRAFDLARLANDDDVMLLDW 508 Query: 396 VYDKLTAPVVDAVCPVASM----HELEKKLCIVGLWCIQMKSHDRPTMSEVIDMLEGGFD 229 V L ++A+ V E ++L V L C Q +RP MSEV+ MLEG D Sbjct: 509 VKGLLKEKKLEALVDVDLQGNYKDEEVEQLIQVALLCTQSSPMERPKMSEVVRMLEG--D 566 Query: 228 GL 223 GL Sbjct: 567 GL 568
>NAK_ARATH (P43293) Probable serine/threonine-protein kinase NAK (EC 2.7.11.1)| Length = 389 Score = 61.2 bits (147), Expect = 2e-09 Identities = 41/118 (34%), Positives = 64/118 (54%), Gaps = 5/118 (4%) Frame = -2 Query: 579 SRALRGTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAANSSQSYYPS 400 S + GT GY APE ++ G +S KSDVYSFG++LLE+ GRR D N + Sbjct: 237 STRVMGTQGYAAPEYLAT--GHLSVKSDVYSFGVVLLELLSGRRAIDKNQPVGEHNLV-D 293 Query: 399 WVYDKLT--APVVDAVCP-VASMHELEK--KLCIVGLWCIQMKSHDRPTMSEVIDMLE 241 W LT ++ + P + + L + K+ ++ L CI + + RPTM+E++ +E Sbjct: 294 WARPYLTNKRRLLRVMDPRLQGQYSLTRALKIAVLALDCISIDAKSRPTMNEIVKTME 351
>SRK6_BRAOE (Q09092) Putative serine/threonine-protein kinase receptor precursor| (EC 2.7.11.1) (S-receptor kinase) (SRK) Length = 849 Score = 61.2 bits (147), Expect = 2e-09 Identities = 42/133 (31%), Positives = 70/133 (52%), Gaps = 10/133 (7%) Frame = -2 Query: 564 GTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNA---DPNAANSSQSY-YPSW 397 GT GY++PE +G S KSDV+SFG+++LE+ G++N + + N SY + W Sbjct: 692 GTYGYMSPEYAM--YGIFSEKSDVFSFGVIVLEIVSGKKNRGFYNLDYENDLLSYVWSRW 749 Query: 396 ----VYDKLTAPVVDAVCPVASMHELEKKL-CI-VGLWCIQMKSHDRPTMSEVIDMLEGG 235 + + +VD++ S+ + ++ L CI +GL C+Q + RP MS V+ M Sbjct: 750 KEGRALEIVDPVIVDSLSSQPSIFQPQEVLKCIQIGLLCVQELAEHRPAMSSVVWMFGSE 809 Query: 234 FDGLQMPSRPFFC 196 + P P +C Sbjct: 810 ATEIPQPKPPGYC 822
>CRI4_MAIZE (O24585) Putative receptor protein kinase CRINKLY4 precursor (EC| 2.7.11.1) Length = 901 Score = 60.8 bits (146), Expect = 3e-09 Identities = 38/112 (33%), Positives = 58/112 (51%), Gaps = 4/112 (3%) Frame = -2 Query: 564 GTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAANSSQSYYPSWVYDK 385 GT+GY+ PE + +++KSDVYSFG++LLE+ GR+ D + W Sbjct: 673 GTLGYLDPEYYRLHY--LTTKSDVYSFGVVLLEILSGRKAID---MQFEEGNIVEWAVPL 727 Query: 384 LTA----PVVDAVCPVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVIDMLE 241 + A ++D V S E KK+ V C++M+ DRP+M +V LE Sbjct: 728 IKAGDIFAILDPVLSPPSDLEALKKIASVACKCVRMRGKDRPSMDKVTTALE 779
>APK1A_ARATH (Q06548) Protein kinase APK1A, chloroplast precursor (EC 2.7.11.1)| Length = 410 Score = 60.5 bits (145), Expect = 4e-09 Identities = 41/117 (35%), Positives = 60/117 (51%), Gaps = 4/117 (3%) Frame = -2 Query: 579 SRALRGTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAANSSQSYY-- 406 S + GT GY APE ++ G +++KSDVYSFG++LLE+ GRR D N + ++ Sbjct: 237 STRVMGTHGYAAPEYLAT--GHLTTKSDVYSFGVVLLELLSGRRAVDKNRPSGERNLVEW 294 Query: 405 --PSWVYDKLTAPVVDAVCPVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVIDMLE 241 P V + V+D E K+ + L C+ + RP MSEV+ LE Sbjct: 295 AKPYLVNKRKIFRVIDNRLQDQYSMEEACKVATLSLRCLTTEIKLRPNMSEVVSHLE 351
>RLK5_ARATH (P47735) Receptor-like protein kinase 5 precursor (EC 2.7.11.1)| Length = 999 Score = 58.9 bits (141), Expect = 1e-08 Identities = 36/111 (32%), Positives = 59/111 (53%), Gaps = 1/111 (0%) Frame = -2 Query: 570 LRGTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAANSSQSYYPSWVY 391 + G+ GYIAPE + ++ KSD+YSFG++LLE+ G++ D + + + Sbjct: 858 IAGSCGYIAPEYVYTL--RVNEKSDIYSFGVVLLELVTGKQPTDSELGDKDMAKWVCTAL 915 Query: 390 DKL-TAPVVDAVCPVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVIDMLE 241 DK PV+D + E+ K + I GL C +RP+M +V+ ML+ Sbjct: 916 DKCGLEPVIDPKLDLKFKEEISKVIHI-GLLCTSPLPLNRPSMRKVVIMLQ 965
>APK1B_ARATH (P46573) Protein kinase APK1B, chloroplast precursor (EC 2.7.11.1)| Length = 412 Score = 57.8 bits (138), Expect = 2e-08 Identities = 39/117 (33%), Positives = 57/117 (48%), Gaps = 4/117 (3%) Frame = -2 Query: 579 SRALRGTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAANSSQSYY-- 406 S + GT GY APE ++ G +++KSDVYS+G++LLE+ GRR D N Q Sbjct: 238 STRIMGTYGYAAPEYLAT--GHLTTKSDVYSYGVVLLEVLSGRRAVDKNRPPGEQKLVEW 295 Query: 405 --PSWVYDKLTAPVVDAVCPVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVIDMLE 241 P + V+D E K+ + L C+ + RP M+EV+ LE Sbjct: 296 ARPLLANKRKLFRVIDNRLQDQYSMEEACKVATLALRCLTFEIKLRPNMNEVVSHLE 352
>RPK1_IPONI (P93194) Receptor-like protein kinase precursor (EC 2.7.11.1)| Length = 1109 Score = 54.7 bits (130), Expect = 2e-07 Identities = 38/125 (30%), Positives = 68/125 (54%), Gaps = 11/125 (8%) Frame = -2 Query: 585 VPSRALRGTIGYIAPEMISRSFGAISSK-SDVYSFGMLLLEMAGGRRNADPNAANSSQSY 409 +PS ++GTIGY+APE +F + S+ SDVYS+G++LLE+ ++ DP+ + ++ Sbjct: 974 IPSNTVQGTIGYMAPE---NAFTTVKSRESDVYSYGVVLLELITRKKALDPSF--NGETD 1028 Query: 408 YPSWV---------YDKLTAP-VVDAVCPVASMHELEKKLCIVGLWCIQMKSHDRPTMSE 259 WV K+ P ++D + + M ++ + L + L C + + RPTM + Sbjct: 1029 IVGWVRSVWTQTGEIQKIVDPSLLDELIDSSVMEQVTEALSL-ALRCAEKEVDKRPTMRD 1087 Query: 258 VIDML 244 V+ L Sbjct: 1088 VVKQL 1092
>EXS_ARATH (Q9LYN8) Leucine-rich repeat receptor protein kinase EXS precursor| (EC 2.7.11.1) (Extra sporogenous cells protein) (EXCESS MICROSPOROCYTES1 protein) Length = 1192 Score = 54.3 bits (129), Expect = 3e-07 Identities = 32/117 (27%), Positives = 54/117 (46%), Gaps = 4/117 (3%) Frame = -2 Query: 579 SRALRGTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAANSSQSYYPS 400 S + GT GYI PE + ++K DVYSFG++LLE+ G+ P+ S Sbjct: 1076 STVIAGTFGYIPPEYGQSA--RATTKGDVYSFGVILLELVTGKEPTGPDFKESEGGNLVG 1133 Query: 399 WVYDKL----TAPVVDAVCPVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVIDMLE 241 W K+ V+D + ++ + +L + + C+ RP M +V+ L+ Sbjct: 1134 WAIQKINQGKAVDVIDPLLVSVALKNSQLRLLQIAMLCLAETPAKRPNMLDVLKALK 1190
>RLCK7_ARATH (Q9LQQ8) Probable serine/threonine-protein kinase RLCKVII (EC| 2.7.11.1) Length = 423 Score = 52.4 bits (124), Expect = 1e-06 Identities = 33/118 (27%), Positives = 56/118 (47%), Gaps = 9/118 (7%) Frame = -2 Query: 579 SRALRGTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAANSSQSYYPS 400 S + GT GY AP+ G ++ KSD+YSFG++LLE+ GR+ D Q+ Sbjct: 264 STRVMGTYGYCAPDYAMT--GQLTFKSDIYSFGVVLLELITGRKAIDNTKTRKDQNLV-G 320 Query: 399 WV---------YDKLTAPVVDAVCPVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVI 253 W + K+ P++ PV +++ + C+Q + RP +S+V+ Sbjct: 321 WARPLFKDRRNFPKMVDPLLQGQYPVRGLYQ----ALAISAMCVQEQPTMRPVVSDVV 374
>PBS1_ARATH (Q9FE20) Serine/threonine-protein kinase PBS1 (EC 2.7.11.1)| (AvrPphB susceptible protein 1) Length = 456 Score = 50.8 bits (120), Expect = 3e-06 Identities = 36/121 (29%), Positives = 58/121 (47%), Gaps = 9/121 (7%) Frame = -2 Query: 579 SRALRGTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAANSSQSYYPS 400 S + GT GY APE G ++ KSDVYSFG++ LE+ GR+ D + Q+ + Sbjct: 247 STRVMGTYGYCAPEYAMT--GQLTVKSDVYSFGVVFLELITGRKAIDSEMPHGEQNLV-A 303 Query: 399 WV---------YDKLTAPVVDAVCPVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVIDM 247 W + KL P + P ++++ V CIQ ++ RP +++V+ Sbjct: 304 WARPLFNDRRKFIKLADPRLKGRFPTRALYQ----ALAVASMCIQEQAATRPLIADVVTA 359 Query: 246 L 244 L Sbjct: 360 L 360
>CLV1_ARATH (Q9SYQ8) Receptor protein kinase CLAVATA1 precursor (EC 2.7.11.1)| Length = 980 Score = 50.8 bits (120), Expect = 3e-06 Identities = 35/117 (29%), Positives = 59/117 (50%), Gaps = 7/117 (5%) Frame = -2 Query: 573 ALRGTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAANSSQSYYPSWV 394 ++ G+ GYIAPE + KSDVYSFG++LLE+ G++ + Sbjct: 853 SIAGSYGYIAPEYAYTL--KVDEKSDVYSFGVVLLELIAGKKPVGEFGEGVDIVRWVRNT 910 Query: 393 YDKLTAP-----VVDAVCPVASMHELEKKLCI--VGLWCIQMKSHDRPTMSEVIDML 244 +++T P VV V P + + L + + + + C++ ++ RPTM EV+ ML Sbjct: 911 EEEITQPSDAAIVVAIVDPRLTGYPLTSVIHVFKIAMMCVEEEAAARPTMREVVHML 967
>KPEL_DROME (Q05652) Probable serine/threonine-protein kinase pelle (EC| 2.7.11.1) Length = 501 Score = 48.9 bits (115), Expect = 1e-05 Identities = 35/115 (30%), Positives = 56/115 (48%), Gaps = 7/115 (6%) Frame = -2 Query: 564 GTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAANSSQS-----YYPS 400 GT Y+ PE R+F +S+ DVYSFG++LLE+ GR+ D N ++ Sbjct: 386 GTKIYLPPEF--RNFRQLSTGVDVYSFGIVLLEVFTGRQVTDRVPENETKKNLLDYVKQQ 443 Query: 399 WVYDKLTAPVVDAVCPVASMHELEKKLCIV--GLWCIQMKSHDRPTMSEVIDMLE 241 W +++ P+ EL+ +C + GL C + DRP+M+ V+ E Sbjct: 444 WRQNRMELLEKHLAAPMGK--ELDMCMCAIEAGLHCTALDPQDRPSMNAVLKRFE 496
>NORK_PEA (Q8LKZ1) Nodulation receptor kinase precursor (EC 2.7.11.1)| Length = 924 Score = 47.8 bits (112), Expect = 2e-05 Identities = 35/116 (30%), Positives = 54/116 (46%), Gaps = 3/116 (2%) Frame = -2 Query: 579 SRALRGTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNAD---PNAANSSQSY 409 S +RGT GY+ PE +S KSDV+SFG++LLE+ GR + P S + Sbjct: 755 SLEVRGTAGYLDPEYYKTQ--QLSEKSDVFSFGVVLLEIVSGREPLNIKRPRVEWSLVEW 812 Query: 408 YPSWVYDKLTAPVVDAVCPVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVIDMLE 241 ++ +VD E ++ V L C++ S RP M +++ LE Sbjct: 813 AKPYIRASKVDEIVDPGIKGGYHAEALWRVVEVALQCLEPYSTYRPCMVDIVRELE 868
>NORK_MEDTR (Q8L4H4) Nodulation receptor kinase precursor (EC 2.7.11.1) (Does not| make infections protein 2) (Symbiosis receptor-like kinase) (MtSYMRK) Length = 925 Score = 47.4 bits (111), Expect = 3e-05 Identities = 35/116 (30%), Positives = 54/116 (46%), Gaps = 3/116 (2%) Frame = -2 Query: 579 SRALRGTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNAD---PNAANSSQSY 409 S +RGT GY+ PE +S KSDV+SFG++LLE+ GR + P S + Sbjct: 756 SLEVRGTAGYLDPEYYKTQ--QLSEKSDVFSFGVVLLEIVSGREPLNIKRPRIEWSLVEW 813 Query: 408 YPSWVYDKLTAPVVDAVCPVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVIDMLE 241 ++ +VD E ++ V L C++ S RP M +++ LE Sbjct: 814 AKPYIRASKVDEIVDPGIKGGYHAEALWRVVEVALQCLEPYSTYRPCMVDIVRELE 869
>PSKR_DAUCA (Q8LPB4) Phytosulfokine receptor precursor (EC 2.7.11.1)| (Phytosulfokine LRR receptor kinase) Length = 1021 Score = 46.6 bits (109), Expect = 5e-05 Identities = 37/116 (31%), Positives = 53/116 (45%), Gaps = 6/116 (5%) Frame = -2 Query: 570 LRGTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAANSSQSYYPSWVY 391 L GT+GYI PE S K DVYSFG++LLE+ GRR D S+ SWV Sbjct: 905 LVGTLGYIPPEYGQASVATY--KGDVYSFGVVLLELLTGRRPMDVCKPRGSRDLI-SWVL 961 Query: 390 ----DKLTAPVVDAVCPVASMHELEKKLCI--VGLWCIQMKSHDRPTMSEVIDMLE 241 +K + + D + E+ L + + C+ RPT +++ LE Sbjct: 962 QMKTEKRESEIFDPF--IYDKDHAEEMLLVLEIACRCLGENPKTRPTTQQLVSWLE 1015
>CX32_ARATH (P27450) Probable serine/threonine-protein kinase Cx32, chloroplast| precursor (EC 2.7.11.1) Length = 419 Score = 46.6 bits (109), Expect = 5e-05 Identities = 32/115 (27%), Positives = 58/115 (50%), Gaps = 5/115 (4%) Frame = -2 Query: 570 LRGTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAANSSQSYYPSWVY 391 + GT GY APE ++ G + KSDV++FG++LLE+ G + +S W+ Sbjct: 255 IMGTYGYAAPEYMAT--GHLYVKSDVFAFGVVLLEIMTGLTAHNTKRPRGQESLV-DWLR 311 Query: 390 DKLT-----APVVDAVCPVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVIDMLE 241 +L+ ++D ++ ++ + L CI+ +RP M EV+++LE Sbjct: 312 PELSNKHRVKQIMDKGIKGQYTTKVATEMARITLSCIEPDPKNRPHMKEVVEVLE 366
>BRI1_ARATH (O22476) BRASSINOSTEROID INSENSITIVE 1 precursor (EC 2.7.11.1)| (AtBRI1) (Brassinosteroid LRR receptor kinase) Length = 1196 Score = 46.2 bits (108), Expect = 7e-05 Identities = 37/115 (32%), Positives = 58/115 (50%), Gaps = 5/115 (4%) Frame = -2 Query: 570 LRGTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAANSSQSYYPSWVY 391 L GT GY+ PE +SF S+K DVYS+G++LLE+ G+R D + + + WV Sbjct: 1046 LAGTPGYVPPEYY-QSFRC-STKGDVYSYGVVLLELLTGKRPTD--SPDFGDNNLVGWVK 1101 Query: 390 DKLTAPVVDAVCPVASMHE--LEKKL---CIVGLWCIQMKSHDRPTMSEVIDMLE 241 + D P + LE +L V + C+ ++ RPTM +V+ M + Sbjct: 1102 QHAKLRISDVFDPELMKEDPALEIELLQHLKVAVACLDDRAWRRPTMVQVMAMFK 1156
>KPRO_MAIZE (P17801) Putative receptor protein kinase ZmPK1 precursor (EC| 2.7.11.1) Length = 817 Score = 46.2 bits (108), Expect = 7e-05 Identities = 35/129 (27%), Positives = 56/129 (43%), Gaps = 20/129 (15%) Frame = -2 Query: 570 LRGTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNAD---------------- 439 +RGT+GYIAPE +S I++K DVYS+G++LLE+ G R ++ Sbjct: 695 VRGTLGYIAPEWVSSL--PITAKVDVYSYGVVLLELLTGTRVSELVGGTDEVHSMLRKLV 752 Query: 438 ----PNAANSSQSYYPSWVYDKLTAPVVDAVCPVASMHELEKKLCIVGLWCIQMKSHDRP 271 QS+ ++ KL PV + + L + + C++ RP Sbjct: 753 RMLSAKLEGEEQSWIDGYLDSKLNRPV---------NYVQARTLIKLAVSCLEEDRSKRP 803 Query: 270 TMSEVIDML 244 TM + L Sbjct: 804 TMEHAVQTL 812
>BRL3_ARATH (Q9LJF3) Serine/threonine-protein kinase BRI1-like 3 precursor (EC| 2.7.11.1) (BRASSINOSTEROID INSENSITIVE 1-like protein 3) Length = 1164 Score = 45.8 bits (107), Expect = 9e-05 Identities = 36/119 (30%), Positives = 58/119 (48%), Gaps = 9/119 (7%) Frame = -2 Query: 570 LRGTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADP-------NAANSSQS 412 L GT GY+ PE +SF ++K DVYS+G++LLE+ G++ DP N ++ Sbjct: 1022 LAGTPGYVPPEYY-QSFRC-TAKGDVYSYGVILLELLSGKKPIDPEEFGEDNNLVGWAKQ 1079 Query: 411 YYPSWVYDKLTAP--VVDAVCPVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVIDMLE 241 Y ++ P V D V +H L+ + C+ + RPTM +V+ M + Sbjct: 1080 LYREKRGAEILDPELVTDKSGDVELLHYLK-----IASQCLDDRPFKRPTMIQVMTMFK 1133
>TMK1_ARATH (P43298) Putative receptor protein kinase TMK1 precursor (EC| 2.7.11.1) Length = 942 Score = 45.8 bits (107), Expect = 9e-05 Identities = 34/120 (28%), Positives = 59/120 (49%), Gaps = 11/120 (9%) Frame = -2 Query: 570 LRGTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAANSSQSYYPSW-- 397 + GT GY+APE G +++K DVYSFG++L+E+ GR++ D + S + SW Sbjct: 753 IAGTFGYLAPEYAVT--GRVTTKVDVYSFGVILMELITGRKSLDESQPEES-IHLVSWFK 809 Query: 396 -VYDKLTAPVVDAVC--------PVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVIDML 244 +Y A A+ +AS+H + + + C + + RP M +++L Sbjct: 810 RMYINKEASFKKAIDTTIDLDEETLASVHTVAE----LAGHCCAREPYQRPDMGHAVNIL 865
>PSKR_ARATH (Q9ZVR7) Putative phytosulfokine receptor precursor (EC 2.7.11.1)| (Phytosulfokine LRR receptor kinase) Length = 1008 Score = 44.7 bits (104), Expect = 2e-04 Identities = 34/119 (28%), Positives = 53/119 (44%), Gaps = 6/119 (5%) Frame = -2 Query: 579 SRALRGTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNAD---PNAANSSQSY 409 S L GT+GYI PE S K DVYSFG++LLE+ +R D P S+ Sbjct: 893 STDLVGTLGYIPPEYGQASVATY--KGDVYSFGVVLLELLTDKRPVDMCKPKGCRDLISW 950 Query: 408 YPSWVYDKLTAPVVDAVCPVASMHELEK---KLCIVGLWCIQMKSHDRPTMSEVIDMLE 241 ++ + V D P+ E +K ++ + C+ RPT +++ L+ Sbjct: 951 VVKMKHESRASEVFD---PLIYSKENDKEMFRVLEIACLCLSENPKQRPTTQQLVSWLD 1006
>BRL1_ARATH (Q9ZWC8) Serine/threonine-protein kinase BRI1-like 1 precursor (EC| 2.7.11.1) (BRASSINOSTEROID INSENSITIVE 1-like protein 1) Length = 1166 Score = 43.9 bits (102), Expect = 3e-04 Identities = 32/114 (28%), Positives = 56/114 (49%), Gaps = 4/114 (3%) Frame = -2 Query: 570 LRGTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADP---NAANSSQSYYPS 400 L GT GY+ PE +SF ++K DVYS+G++LLE+ G++ DP N+ + Sbjct: 1024 LAGTPGYVPPEYY-QSFRC-TAKGDVYSYGVILLELLSGKKPIDPGEFGEDNNLVGWAKQ 1081 Query: 399 WVYDKLTAPVVDAVCPVASMHELEK-KLCIVGLWCIQMKSHDRPTMSEVIDMLE 241 +K A ++D ++E + C+ + RPTM +++ M + Sbjct: 1082 LYREKRGAEILDPELVTDKSGDVELFHYLKIASQCLDDRPFKRPTMIQLMAMFK 1135
>M3K9_HUMAN (P80192) Mitogen-activated protein kinase kinase kinase 9 (EC| 2.7.11.25) (Mixed lineage kinase 1) Length = 1104 Score = 42.7 bits (99), Expect = 8e-04 Identities = 38/131 (29%), Positives = 56/131 (42%), Gaps = 4/131 (3%) Frame = -2 Query: 564 GTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAANSSQSYYPSWVYDK 385 GT ++APE+I S S SDV+S+G+LL E+ G P + +K Sbjct: 311 GTYAWMAPEVIRASM--FSKGSDVWSYGVLLWELLTGE---VPFRGIDGLAVAYGVAMNK 365 Query: 384 LTAPVVDAVCPVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVIDML----EGGFDGLQM 217 L P + + CP +E C H RP+ + ++D L E GF +M Sbjct: 366 LALP-IPSTCPEPFAKLMED--------CWNPDPHSRPSFTNILDQLTTIEESGF--FEM 414 Query: 216 PSRPFFCDDDH 184 P F C D+ Sbjct: 415 PKDSFHCLQDN 425
>BRI1_LYCPE (Q8L899) Systemin receptor SR160 precursor (EC 2.7.11.1)| (Brassinosteroid LRR receptor kinase) Length = 1207 Score = 42.7 bits (99), Expect = 8e-04 Identities = 38/133 (28%), Positives = 60/133 (45%), Gaps = 5/133 (3%) Frame = -2 Query: 570 LRGTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAANSSQSYYPSWVY 391 L GT GY+ PE +SF S+K DVYS+G++LLE+ G++ D +A+ + WV Sbjct: 1051 LAGTPGYVPPEYY-QSFRC-STKGDVYSYGVVLLELLTGKQPTD--SADFGDNNLVGWVK 1106 Query: 390 DKLTAPVVDAVCPVASMHELEKKLCI-----VGLWCIQMKSHDRPTMSEVIDMLEGGFDG 226 + D + ++ + V C+ + RPTM +V+ M + G Sbjct: 1107 LHAKGKITDVFDRELLKEDASIEIELLQHLKVACACLDDRHWKRPTMIQVMAMFKEIQAG 1166 Query: 225 LQMPSRPFFCDDD 187 M S DD Sbjct: 1167 SGMDSTSTIGADD 1179
>BRI1_LYCES (Q8GUQ5) Brassinosteroid LRR receptor kinase precursor (EC 2.7.11.1)| (tBRI1) (Altered brassinolide sensitivity 1) (Systemin receptor SR160) Length = 1207 Score = 42.7 bits (99), Expect = 8e-04 Identities = 38/133 (28%), Positives = 60/133 (45%), Gaps = 5/133 (3%) Frame = -2 Query: 570 LRGTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAANSSQSYYPSWVY 391 L GT GY+ PE +SF S+K DVYS+G++LLE+ G++ D +A+ + WV Sbjct: 1051 LAGTPGYVPPEYY-QSFRC-STKGDVYSYGVVLLELLTGKQPTD--SADFGDNNLVGWVK 1106 Query: 390 DKLTAPVVDAVCPVASMHELEKKLCI-----VGLWCIQMKSHDRPTMSEVIDMLEGGFDG 226 + D + ++ + V C+ + RPTM +V+ M + G Sbjct: 1107 LHAKGKITDVFDRELLKEDASIEIELLQHLKVACACLDDRHWKRPTMIQVMAMFKEIQAG 1166 Query: 225 LQMPSRPFFCDDD 187 M S DD Sbjct: 1167 SGMDSTSTIGADD 1179
>IRAK4_MOUSE (Q8R4K2) Interleukin-1 receptor-associated kinase 4 (EC 2.7.11.1)| (IRAK-4) Length = 459 Score = 41.6 bits (96), Expect = 0.002 Identities = 21/44 (47%), Positives = 28/44 (63%) Frame = -2 Query: 564 GTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADPN 433 GT Y+APE + G I+ KSD+YSFG++LLE+ G D N Sbjct: 350 GTTAYMAPEALR---GEITPKSDIYSFGVVLLELITGLAAVDEN 390
>IRAK4_HUMAN (Q9NWZ3) Interleukin-1 receptor-associated kinase 4 (EC 2.7.11.1)| (IRAK-4) (NY-REN-64 antigen) Length = 460 Score = 40.4 bits (93), Expect = 0.004 Identities = 32/110 (29%), Positives = 50/110 (45%), Gaps = 2/110 (1%) Frame = -2 Query: 564 GTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAANSSQSYYPSWVYD- 388 GT Y+APE + G I+ KSD+YSFG++LLE+ G D + + D Sbjct: 350 GTTAYMAPEALR---GEITPKSDIYSFGVVLLEIITGLPAVDEHREPQLLLDIKEEIEDE 406 Query: 387 -KLTAPVVDAVCPVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVIDMLE 241 K +D A +E + V C+ K + RP + +V +L+ Sbjct: 407 EKTIEDYIDKKMNDADSTSVE-AMYSVASQCLHEKKNKRPDIKKVQQLLQ 455
>SIRK_ARATH (O64483) Senescence-induced receptor-like serine/threonine-protein| kinase precursor (FLG22-induced receptor-like kinase 1) Length = 876 Score = 40.0 bits (92), Expect = 0.005 Identities = 35/115 (30%), Positives = 54/115 (46%), Gaps = 6/115 (5%) Frame = -2 Query: 579 SRALRGTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAANSS------ 418 S + G+IGY+ PE S ++ KSDVYS G++LLE+ G+ P A+S Sbjct: 731 STVVAGSIGYLDPEYYSTR--QMNEKSDVYSLGVVLLEVITGQ----PAIASSKTEKVHI 784 Query: 417 QSYYPSWVYDKLTAPVVDAVCPVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVI 253 + S + + +VD K+ + L C + S RPTMS+V+ Sbjct: 785 SDHVRSILANGDIRGIVDQRLRERYDVGSAWKMSEIALACTEHTSAQRPTMSQVV 839
>LRRK2_HUMAN (Q5S007) Leucine-rich repeat serine/threonine-protein kinase 2 (EC| 2.7.11.1) (Dardarin) Length = 2527 Score = 40.0 bits (92), Expect = 0.005 Identities = 34/110 (30%), Positives = 54/110 (49%), Gaps = 3/110 (2%) Frame = -2 Query: 564 GTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEM--AGGRRNADPNAANSSQSYYPSWVY 391 GT G+ APE ++R + ++DVYSFG+LL ++ GGR N + Sbjct: 2034 GTPGFRAPE-VARGNVIYNQQADVYSFGLLLYDILTTGGRIVEGLKFPNEFDELE---IQ 2089 Query: 390 DKLTAPVVDAVC-PVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVIDML 244 KL PV + C P + +L K+ C++ +RPT ++V D+L Sbjct: 2090 GKLPDPVKEYGCAPWPMVEKLIKQ-------CLKENPQERPTSAQVFDIL 2132
>RIPK3_HUMAN (Q9Y572) Receptor-interacting serine/threonine-protein kinase 3 (EC| 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3) Length = 518 Score = 40.0 bits (92), Expect = 0.005 Identities = 23/59 (38%), Positives = 31/59 (52%) Frame = -2 Query: 564 GTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAANSSQSYYPSWVYD 388 GT+GY+APE+ S+ SDVYSFG+L+ + GR P PS VY+ Sbjct: 181 GTLGYLAPELFVNVNRKASTASDVYSFGILMWAVLAGREVELPTE--------PSLVYE 231
>MKH1_SCHPO (Q10407) MAP kinase kinase kinase mkh1 (EC 2.7.11.25)| Length = 1116 Score = 39.7 bits (91), Expect = 0.007 Identities = 18/42 (42%), Positives = 29/42 (69%) Frame = -2 Query: 573 ALRGTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRR 448 +++G+I ++APE+I S+K DV+S G ++LEM GRR Sbjct: 991 SMQGSIFWMAPEVIHNDHQGYSAKVDVWSLGCVVLEMLAGRR 1032
>RIPK3_RAT (Q9Z2P5) Receptor-interacting serine/threonine-protein kinase 3 (EC| 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3) (Homocysteine respondent protein HCYP2) Length = 478 Score = 39.7 bits (91), Expect = 0.007 Identities = 20/43 (46%), Positives = 27/43 (62%) Frame = -2 Query: 579 SRALRGTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGR 451 SR GT+ Y+APE++ G S SDVYSFG+L+ + GR Sbjct: 179 SRDSGGTLAYLAPELLDND-GKASKASDVYSFGVLVWTVLAGR 220
>YR831_MIMIV (Q7T6Y2) Putative serine/threonine-protein kinase/receptor R831| precursor (EC 2.7.11.1) Length = 1624 Score = 39.3 bits (90), Expect = 0.009 Identities = 33/108 (30%), Positives = 50/108 (46%), Gaps = 1/108 (0%) Frame = -2 Query: 564 GTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRN-ADPNAANSSQSYYPSWVYD 388 GT + APE+I K+DV+SFG+++ E+ G+ A+ N S Sbjct: 1522 GTPCWTAPEVIRGE--KYCEKADVFSFGVVMWEVLTGKEPFAECNFMKVSLDILEGG--- 1576 Query: 387 KLTAPVVDAVCPVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVIDML 244 P++ + CP HE K + C K+H RPTM+EV+ L Sbjct: 1577 ---RPIIPSDCP----HEFAKLI----KKCWHAKAHKRPTMTEVVQQL 1613 Score = 35.4 bits (80), Expect = 0.12 Identities = 30/107 (28%), Positives = 48/107 (44%) Frame = -2 Query: 564 GTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAANSSQSYYPSWVYDK 385 GTI +IAPE+++ S +DVYSFG++L E+ P + + S + D Sbjct: 947 GTIHWIAPEILNDSTEVDYILADVYSFGIILWELL---TREQPYKGMTPAAIAVSVIRDG 1003 Query: 384 LTAPVVDAVCPVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVIDML 244 + P+ D + H +E I W + RPT E++ L Sbjct: 1004 MRPPISD---EAVTAHSIEYIDLIKQCW--HSDTIIRPTFLEIMTRL 1045
>BCK1_YEAST (Q01389) Serine/threonine-protein kinase BCK1/SLK1/SSP31 (EC| 2.7.11.1) Length = 1478 Score = 39.3 bits (90), Expect = 0.009 Identities = 18/41 (43%), Positives = 29/41 (70%) Frame = -2 Query: 570 LRGTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRR 448 +RGT+ ++APEM+ G S+K D++S G ++LEM G+R Sbjct: 1339 MRGTVFWMAPEMVDTKQG-YSAKVDIWSLGCIVLEMFAGKR 1378
>M3K10_HUMAN (Q02779) Mitogen-activated protein kinase kinase kinase 10 (EC| 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST) Length = 954 Score = 39.3 bits (90), Expect = 0.009 Identities = 33/108 (30%), Positives = 47/108 (43%) Frame = -2 Query: 564 GTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAANSSQSYYPSWVYDK 385 GT ++APE+I S S SDV+SFG+LL E+ G P + + +K Sbjct: 265 GTYAWMAPEVIRLSL--FSKSSDVWSFGVLLWELLTGE---VPYREIDALAVAYGVAMNK 319 Query: 384 LTAPVVDAVCPVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVIDMLE 241 LT P + + CP LE+ C H RP ++ LE Sbjct: 320 LTLP-IPSTCPEPFARLLEE--------CWDPDPHGRPDFGSILKRLE 358
>IRAK3_MOUSE (Q8K4B2) Interleukin-1 receptor-associated kinase 3 (EC 2.7.11.1)| (IRAK-3) (IL-1 receptor-associated kinase M) (IRAK-M) Length = 609 Score = 38.9 bits (89), Expect = 0.011 Identities = 43/158 (27%), Positives = 66/158 (41%), Gaps = 8/158 (5%) Frame = -2 Query: 567 RGTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNA--DPNAANSSQSYYPSWV 394 R + Y+ E I + G +S K+DVYSFG++++E+ G + DP Sbjct: 348 RKHLWYMPEEYIRQ--GRLSVKTDVYSFGIVIMEVLTGCKVVLDDPKHVQLRDLLMELME 405 Query: 393 YDKLTA--PVVDAVCPVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVIDMLEGGFDGLQ 220 L + +D P + K + G C+ K+ RPTM EV+ LE L Sbjct: 406 KRGLDSCLSFLDRKIPPCPRNFSAKLFSLAGR-CVATKAKLRPTMDEVLSSLESTQPSL- 463 Query: 219 MPSRPFFCDDDHTAVPD----SYPLLSELTEISEEDDE 118 +F +D T++ S L + I EDDE Sbjct: 464 -----YFAEDPPTSLKSFRCPSPLFLDNVPSIPVEDDE 496
>IRAK3_HUMAN (Q9Y616) Interleukin-1 receptor-associated kinase 3 (EC 2.7.11.1)| (IRAK-3) (IL-1 receptor-associated kinase M) (IRAK-M) Length = 596 Score = 38.5 bits (88), Expect = 0.015 Identities = 42/153 (27%), Positives = 65/153 (42%), Gaps = 8/153 (5%) Frame = -2 Query: 552 YIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNA--DPNAANSSQSYYPSWVYDKLT 379 Y+ E I + G +S K+DVYSFG++++E+ G R DP L Sbjct: 340 YMPEEYIRQ--GKLSIKTDVYSFGIVIMEVLTGCRVVLDDPKHIQLRDLLRELMEKRGLD 397 Query: 378 A--PVVDAVCPVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVIDMLEGGFDGLQMPSRP 205 + +D P + K C+ G C ++ RP+M EV++ LE L Sbjct: 398 SCLSFLDKKVPPCPRNFSAKLFCLAGR-CAATRAKLRPSMDEVLNTLESTQASL------ 450 Query: 204 FFCDDDHTAVPD----SYPLLSELTEISEEDDE 118 +F +D T++ S L + I EDDE Sbjct: 451 YFAEDPPTSLKSFRCPSPLFLENVPSIPVEDDE 483
>TMKL1_ARATH (P33543) Putative kinase-like protein TMKL1 precursor| Length = 674 Score = 37.7 bits (86), Expect = 0.025 Identities = 32/112 (28%), Positives = 51/112 (45%), Gaps = 7/112 (6%) Frame = -2 Query: 555 GYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRR----NADPNAANSSQSYYPSWVYD 388 GY APE+ + +SDVY+FG+LLLE+ G++ + N S + V + Sbjct: 541 GYKAPEL--HKMKKCNPRSDVYAFGILLLEILMGKKPGKSGRNGNEFVDLPSLVKAAVLE 598 Query: 387 KLTAPVVDAVCPVASMHELEKKL---CIVGLWCIQMKSHDRPTMSEVIDMLE 241 + T V D +E+ L + + C + RP+M EV+ LE Sbjct: 599 ETTMEVFDLEAMKGIRSPMEEGLVHALKLAMGCCAPVTTVRPSMEEVVKQLE 650
>M3KL4_HUMAN (Q5TCX8) Mitogen-activated protein kinase kinase kinase (EC| 2.7.11.25) (Mixed lineage kinase 4) Length = 1036 Score = 37.7 bits (86), Expect = 0.025 Identities = 34/128 (26%), Positives = 55/128 (42%), Gaps = 2/128 (1%) Frame = -2 Query: 564 GTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAANSSQSYYPSWVYDK 385 GT ++APE+I S S SD++S+G+LL E+ G P + +K Sbjct: 306 GTYAWMAPEVIKSSL--FSKGSDIWSYGVLLWELLTGE---VPYRGIDGLAVAYGVAVNK 360 Query: 384 LTAPVVDAVCPVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVIDMLEG--GFDGLQMPS 211 LT P + + CP +++ C Q H RP+ + +++ L G +MP Sbjct: 361 LTLP-IPSTCPEPFAKLMKE--------CWQQDPHIRPSFALILEQLTAIEGAVMTEMPQ 411 Query: 210 RPFFCDDD 187 F D Sbjct: 412 ESFHSMQD 419
>ANKK1_HUMAN (Q8NFD2) Ankyrin repeat and protein kinase domain-containing| protein 1 (EC 2.7.11.1) (Protein kinase PKK2) (X-kinase) (SgK288) Length = 765 Score = 37.7 bits (86), Expect = 0.025 Identities = 18/42 (42%), Positives = 25/42 (59%) Frame = -2 Query: 588 FVPSRALRGTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEM 463 ++ ALRG + YI PEM S A K DVYSF +++ E+ Sbjct: 178 YIERSALRGMLSYIPPEMFLESNKAPGPKYDVYSFAIVIWEL 219
>RIPK3_MOUSE (Q9QZL0) Receptor-interacting serine/threonine-protein kinase 3 (EC| 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3) (mRIP3) Length = 486 Score = 37.4 bits (85), Expect = 0.033 Identities = 29/107 (27%), Positives = 49/107 (45%) Frame = -2 Query: 579 SRALRGTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAANSSQSYYPS 400 SR GT+ Y+ PE++ + S SDVYSFG+L+ + GR S Sbjct: 181 SRDSGGTLAYLDPELLFKVNLKASKASDVYSFGILVWAVLAGRE----AELVDKTSLIRE 236 Query: 399 WVYDKLTAPVVDAVCPVASMHELEKKLCIVGLWCIQMKSHDRPTMSE 259 V D+ + P + + P + +KL + + C +S +RP+ + Sbjct: 237 TVCDRQSRPPLTELPPGSPETPGLEKLKELMIHCWGSQSENRPSFQD 283
>M3LK7_DROME (P83104) Putative mitogen-activated protein kinase kinase kinase| 7-like (EC 2.7.11.25) Length = 393 Score = 37.4 bits (85), Expect = 0.033 Identities = 30/109 (27%), Positives = 50/109 (45%), Gaps = 4/109 (3%) Frame = -2 Query: 570 LRGTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGR----RNADPNAANSSQSYYP 403 ++GT+ Y+APE I ++K DVYSFG++L E+ + +PN+ + Sbjct: 166 MQGTLRYMAPEAIKHL--KYTAKCDVYSFGIMLWELMTRQLPYSHLENPNSQYAIMKAIS 223 Query: 402 SWVYDKLTAPVVDAVCPVASMHELEKKLCIVGLWCIQMKSHDRPTMSEV 256 S +KL V + CP +E C+ + RP+M E+ Sbjct: 224 SG--EKLPMEAVRSDCPEGIKQLME--------CCMDINPEKRPSMKEI 262
>BRL2_ARATH (Q9ZPS9) Serine/threonine-protein kinase BRI1-like 2 precursor (EC| 2.7.11.1) (BRASSINOSTEROID INSENSITIVE 1-like protein 2) (Protein VASCULAR HIGHWAY 1) Length = 1143 Score = 37.4 bits (85), Expect = 0.033 Identities = 20/44 (45%), Positives = 29/44 (65%) Frame = -2 Query: 570 LRGTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNAD 439 L GT GY+ PE +SF ++K DVYS G+++LE+ G+R D Sbjct: 1003 LAGTPGYVPPEYY-QSFRC-TAKGDVYSIGVVMLEILSGKRPTD 1044
>ANKK1_MOUSE (Q8BZ25) Ankyrin repeat and protein kinase domain-containing| protein 1 (EC 2.7.11.1) Length = 745 Score = 37.0 bits (84), Expect = 0.043 Identities = 17/42 (40%), Positives = 26/42 (61%) Frame = -2 Query: 588 FVPSRALRGTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEM 463 ++ ALRGT+ YI PEM + A + DVYSF +++ E+ Sbjct: 190 YIERSALRGTLSYIPPEMFLENNKAPGPEYDVYSFAIVIWEI 231
>FGR_FSVGR (P00544) Tyrosine-protein kinase transforming protein Fgr (EC| 2.7.10.2) Length = 545 Score = 37.0 bits (84), Expect = 0.043 Identities = 34/121 (28%), Positives = 50/121 (41%) Frame = -2 Query: 582 PSRALRGTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAANSSQSYYP 403 P + + I + APE + FG + KSDV+SFG+LL E+ R P N Sbjct: 437 PRQGAKFPIKWTAPE--AALFGRFTIKSDVWSFGILLTELISKGRVPYPGMNNREVLEQV 494 Query: 402 SWVYDKLTAPVVDAVCPVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVIDMLEGGFDGL 223 Y P CP + +E+ W ++ +RPT + LE F+G Sbjct: 495 EHGYHMPCPP----GCPASLYEAMEQ------TW--RLDPEERPTFEYLQSFLEDYFNGP 542 Query: 222 Q 220 Q Sbjct: 543 Q 543
>IRAK1_MOUSE (Q62406) Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1)| (IRAK-1) (IRAK) (Pelle-like protein kinase) (mPLK) Length = 710 Score = 36.6 bits (83), Expect = 0.056 Identities = 34/139 (24%), Positives = 57/139 (41%), Gaps = 28/139 (20%) Frame = -2 Query: 570 LRGTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAANSS--------- 418 +RGT+ Y+ E I G ++ +D +SFG+++LE G+R A + Sbjct: 384 VRGTLAYLPEEYIKT--GRLAVDTDTFSFGVVILETLAGQRAVRTQGAKTKYLKDLIEDE 441 Query: 417 --------QSYYPS-WV---YDKLTAPVVDAVC-------PVASMHELEKKLCIVGLWCI 295 +S P+ WV D AP+ + P +L L + C+ Sbjct: 442 AEEAGVTLKSTQPTLWVGVATDAWAAPIAAQIYKKHLDSRPGPCPPQLGLALAQLACCCM 501 Query: 294 QMKSHDRPTMSEVIDMLEG 238 ++ RP M++V LEG Sbjct: 502 HRRAKKRPPMTQVYKRLEG 520
>LRRK2_MOUSE (Q5S006) Leucine-rich repeat serine/threonine-protein kinase 2 (EC| 2.7.11.1) Length = 2527 Score = 36.6 bits (83), Expect = 0.056 Identities = 33/110 (30%), Positives = 52/110 (47%), Gaps = 3/110 (2%) Frame = -2 Query: 564 GTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEM--AGGRRNADPNAANSSQSYYPSWVY 391 GT G+ APE ++R + ++DVYSFG+LL ++ G R N + Sbjct: 2034 GTPGFRAPE-VARGNVIYNQQADVYSFGLLLHDIWTTGSRIMEGLRFPNEFDELA---IQ 2089 Query: 390 DKLTAPVVDAVC-PVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVIDML 244 KL PV + C P + +L K C++ +RPT ++V D+L Sbjct: 2090 GKLPDPVKEYGCAPWPMVEKLITK-------CLKENPQERPTSAQVFDIL 2132
>YES_XENLA (P10936) Tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes)| Length = 536 Score = 36.6 bits (83), Expect = 0.056 Identities = 35/118 (29%), Positives = 50/118 (42%) Frame = -2 Query: 558 IGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAANSSQSYYPSWVYDKLT 379 I + APE + +G + KSDV+SFG+LL E+ R P N Y ++ Sbjct: 429 IKWTAPE--AALYGRFTIKSDVWSFGILLTELVAKGRVPYPGMVNREVLEQVERGY-RMP 485 Query: 378 APVVDAVCPVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVIDMLEGGFDGLQMPSRP 205 P CP S+HEL K C + +RPT + LE F + +P Sbjct: 486 CP---QRCP-ESLHELMK-------LCWKKDPDERPTFEYIQSFLEDYFTATEPQYQP 532
>EPHA4_MOUSE (Q03137) Ephrin type-A receptor 4 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor SEK) (MPK-3) Length = 986 Score = 36.2 bits (82), Expect = 0.073 Identities = 33/107 (30%), Positives = 55/107 (51%), Gaps = 1/107 (0%) Frame = -2 Query: 558 IGYIAPEMISRSFGAISSKSDVYSFGMLLLE-MAGGRRNADPNAANSSQSYYPSWVYDKL 382 I + APE I+ + +S SDV+S+G+++ E M+ G R P S+Q + Sbjct: 788 IRWTAPEAIA--YRKFTSASDVWSYGIVMWEVMSYGER---PYWDMSNQDVIKAIEEGYR 842 Query: 381 TAPVVDAVCPVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVIDMLE 241 P +D CP+A +H+L L C Q + DRP ++++ML+ Sbjct: 843 LPPPMD--CPIA-LHQLM-------LDCWQKERSDRPKFGQIVNMLD 879
>EPHA4_HUMAN (P54764) Ephrin type-A receptor 4 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor SEK) (Receptor protein-tyrosine kinase HEK8) Length = 986 Score = 36.2 bits (82), Expect = 0.073 Identities = 33/107 (30%), Positives = 55/107 (51%), Gaps = 1/107 (0%) Frame = -2 Query: 558 IGYIAPEMISRSFGAISSKSDVYSFGMLLLE-MAGGRRNADPNAANSSQSYYPSWVYDKL 382 I + APE I+ + +S SDV+S+G+++ E M+ G R P S+Q + Sbjct: 788 IRWTAPEAIA--YRKFTSASDVWSYGIVMWEVMSYGER---PYWDMSNQDVIKAIEEGYR 842 Query: 381 TAPVVDAVCPVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVIDMLE 241 P +D CP+A +H+L L C Q + DRP ++++ML+ Sbjct: 843 LPPPMD--CPIA-LHQLM-------LDCWQKERSDRPKFGQIVNMLD 879
>EPHA4_CHICK (Q07496) Ephrin type-A receptor 4 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor CEK8) Length = 986 Score = 36.2 bits (82), Expect = 0.073 Identities = 33/107 (30%), Positives = 55/107 (51%), Gaps = 1/107 (0%) Frame = -2 Query: 558 IGYIAPEMISRSFGAISSKSDVYSFGMLLLE-MAGGRRNADPNAANSSQSYYPSWVYDKL 382 I + APE I+ + +S SDV+S+G+++ E M+ G R P S+Q + Sbjct: 788 IRWTAPEAIA--YRKFTSASDVWSYGIVMWEVMSYGER---PYWDMSNQDVIKAIEEGYR 842 Query: 381 TAPVVDAVCPVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVIDMLE 241 P +D CP+A +H+L L C Q + DRP ++++ML+ Sbjct: 843 LPPPMD--CPIA-LHQLM-------LDCWQKERSDRPKFGQIVNMLD 879
>M3K11_HUMAN (Q16584) Mitogen-activated protein kinase kinase kinase 11 (EC| 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline-rich kinase) Length = 847 Score = 36.2 bits (82), Expect = 0.073 Identities = 31/108 (28%), Positives = 45/108 (41%) Frame = -2 Query: 564 GTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAANSSQSYYPSWVYDK 385 GT ++APE+I S S SDV+SFG+LL E+ G P + +K Sbjct: 284 GTYAWMAPEVIKAS--TFSKGSDVWSFGVLLWELLTGE---VPYRGIDCLAVAYGVAVNK 338 Query: 384 LTAPVVDAVCPVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVIDMLE 241 LT P + + CP + C H RP + ++ LE Sbjct: 339 LTLP-IPSTCPEPFAQLMAD--------CWAQDPHRRPDFASILQQLE 377
>EPA4A_BRARE (O13148) Ephrin type-A receptor 4a (EC 2.7.10.1) (Tyrosine-protein| kinase receptor ZEK2) (EPH-like kinase 2) (Fragment) Length = 292 Score = 36.2 bits (82), Expect = 0.073 Identities = 34/107 (31%), Positives = 56/107 (52%), Gaps = 1/107 (0%) Frame = -2 Query: 558 IGYIAPEMISRSFGAISSKSDVYSFGMLLLE-MAGGRRNADPNAANSSQSYYPSWVYDKL 382 I + APE I+ + +S SDV+S+G+++ E M+ G R P S+Q + Sbjct: 171 IRWTAPEAIT--YRKFTSASDVWSYGIVMWEVMSYGER---PYWDMSNQDVIKAIEEGYR 225 Query: 381 TAPVVDAVCPVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVIDMLE 241 P +D CPV S+H+L L C Q + +RP S++++ML+ Sbjct: 226 LPPPMD--CPV-SLHQLM-------LDCWQKERAERPKFSQIVNMLD 262
>YES_CHICK (P09324) Tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes)| Length = 540 Score = 35.8 bits (81), Expect = 0.095 Identities = 35/118 (29%), Positives = 50/118 (42%) Frame = -2 Query: 558 IGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAANSSQSYYPSWVYDKLT 379 I + APE + +G + KSDV+SFG+LL E+ R P N Y ++ Sbjct: 433 IKWTAPE--AALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMVNREVLEQVERGY-RMP 489 Query: 378 APVVDAVCPVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVIDMLEGGFDGLQMPSRP 205 P CP S+HEL K C + +RPT + LE F + +P Sbjct: 490 CP---QGCP-ESLHELMK-------LCWKKDPDERPTFEYIQSFLEDYFTATEPQYQP 536
>PK1_STRTO (Q9KIG4) Serine/threonine-protein kinase PK-1 (EC 2.7.11.1)| (stoPK-1) Length = 641 Score = 35.8 bits (81), Expect = 0.095 Identities = 18/42 (42%), Positives = 24/42 (57%) Frame = -2 Query: 564 GTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNAD 439 GT+ Y+APE I G + DVY+ G+LL EM G + D Sbjct: 178 GTVSYLAPEQIEH--GTADPRVDVYACGILLYEMLTGEKPHD 217
>M3K8_RAT (Q63562) Mitogen-activated protein kinase kinase kinase 8 (EC| 2.7.11.25) (Tumor progression locus 2) (TPL-2) Length = 467 Score = 35.8 bits (81), Expect = 0.095 Identities = 23/60 (38%), Positives = 33/60 (55%) Frame = -2 Query: 570 LRGTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAANSSQSYYPSWVY 391 LRGT Y++PE+I S+K+D+YS G L+ M G P +S YPS++Y Sbjct: 287 LRGTEIYMSPEVILCR--GHSTKADIYSLGATLIHMQTG---TPPWVKRYPRSAYPSYLY 341
>M3K8_MOUSE (Q07174) Mitogen-activated protein kinase kinase kinase 8 (EC| 2.7.11.25) (COT proto-oncogene serine/threonine-protein kinase) (C-COT) (Cancer Osaka thyroid oncogene) Length = 467 Score = 35.8 bits (81), Expect = 0.095 Identities = 23/60 (38%), Positives = 33/60 (55%) Frame = -2 Query: 570 LRGTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAANSSQSYYPSWVY 391 LRGT Y++PE+I S+K+D+YS G L+ M G P +S YPS++Y Sbjct: 287 LRGTEIYMSPEVILCR--GHSTKADIYSLGATLIHMQTG---TPPWVKRYPRSAYPSYLY 341
>M3K8_HUMAN (P41279) Mitogen-activated protein kinase kinase kinase 8 (EC| 2.7.11.25) (COT proto-oncogene serine/threonine-protein kinase) (C-COT) (Cancer Osaka thyroid oncogene) Length = 467 Score = 35.8 bits (81), Expect = 0.095 Identities = 23/60 (38%), Positives = 33/60 (55%) Frame = -2 Query: 570 LRGTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAANSSQSYYPSWVY 391 LRGT Y++PE+I S+K+D+YS G L+ M G P +S YPS++Y Sbjct: 287 LRGTEIYMSPEVILCR--GHSTKADIYSLGATLIHMQTG---TPPWVKRYPRSAYPSYLY 341
>YES_XIPHE (P27447) Tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes)| Length = 543 Score = 35.8 bits (81), Expect = 0.095 Identities = 33/118 (27%), Positives = 52/118 (44%) Frame = -2 Query: 558 IGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAANSSQSYYPSWVYDKLT 379 I + APE + +G + KSDV+SFG+LL E+ R P N Y ++ Sbjct: 436 IKWTAPE--AALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMVNREVLEQVDRGY-RMP 492 Query: 378 APVVDAVCPVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVIDMLEGGFDGLQMPSRP 205 P CP S+HE+ ++ C + + +RPT + LE F + +P Sbjct: 493 CP---QGCP-ESLHEMMRQ-------CWKKEPDERPTFEYIQSFLEDYFTATEPQYQP 539
>EPA4A_XENLA (Q91845) Ephrin type-A receptor 4-A precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor SEK-1) (xSEK-1) Length = 986 Score = 35.8 bits (81), Expect = 0.095 Identities = 33/107 (30%), Positives = 54/107 (50%), Gaps = 1/107 (0%) Frame = -2 Query: 558 IGYIAPEMISRSFGAISSKSDVYSFGMLLLE-MAGGRRNADPNAANSSQSYYPSWVYDKL 382 I + APE I+ + +S SDV+S+G+++ E M+ G R P S+Q + Sbjct: 787 IRWTAPEAIA--YRKFTSASDVWSYGIVMWEVMSYGER---PYWDMSNQDVIKAIEEGYR 841 Query: 381 TAPVVDAVCPVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVIDMLE 241 P +D CP+A +H+L L C Q + DRP +++ ML+ Sbjct: 842 LPPPMD--CPIA-LHQLM-------LDCWQKERSDRPKFGQIVSMLD 878
>LYN_MOUSE (P25911) Tyrosine-protein kinase Lyn (EC 2.7.10.2)| Length = 511 Score = 35.8 bits (81), Expect = 0.095 Identities = 26/57 (45%), Positives = 33/57 (57%), Gaps = 7/57 (12%) Frame = -2 Query: 558 IGYIAPEMISRSFGAISSKSDVYSFGMLLLEMA-------GGRRNADPNAANSSQSY 409 I + APE I+ FG + KSDV+SFG+LL E+ GR NAD +A SQ Y Sbjct: 406 IKWTAPEAIN--FGCFTIKSDVWSFGILLYEIVTYGKIPYPGRTNADVMSA-LSQGY 459
>LYN_HUMAN (P07948) Tyrosine-protein kinase Lyn (EC 2.7.10.2)| Length = 511 Score = 35.8 bits (81), Expect = 0.095 Identities = 36/113 (31%), Positives = 53/113 (46%), Gaps = 7/113 (6%) Frame = -2 Query: 558 IGYIAPEMISRSFGAISSKSDVYSFGMLLLEMA-------GGRRNADPNAANSSQSYYPS 400 I + APE I+ FG + KSDV+SFG+LL E+ GR NAD A SQ Y Sbjct: 406 IKWTAPEAIN--FGCFTIKSDVWSFGILLYEIVTYGKIPYPGRTNADVMTA-LSQGYRMP 462 Query: 399 WVYDKLTAPVVDAVCPVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVIDMLE 241 V + CP ++++ K C + K+ +RPT + +L+ Sbjct: 463 RVEN----------CP-DELYDIMK-------MCWKEKAEERPTFDYLQSVLD 497
>KSG1_SCHPO (Q12701) Serine/threonine-protein kinase ksg1 (EC 2.7.11.1)| Length = 592 Score = 35.8 bits (81), Expect = 0.095 Identities = 30/108 (27%), Positives = 54/108 (50%) Frame = -2 Query: 579 SRALRGTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAANSSQSYYPS 400 SR+ GT Y++PE++S +S D+++FG +L +M G+ P A + + S Sbjct: 269 SRSFVGTARYVSPEVLSDKIAGTAS--DIWAFGCILFQMLAGK---PPFVAGNEYLTFQS 323 Query: 399 WVYDKLTAPVVDAVCPVASMHELEKKLCIVGLWCIQMKSHDRPTMSEV 256 ++ L+ + + VAS +L KKL + + DR T+ E+ Sbjct: 324 ILH--LSYEIPPDISDVAS--DLIKKLLV-------LDPKDRLTVDEI 360
>HCK_MOUSE (P08103) Tyrosine-protein kinase HCK (EC 2.7.10.2)| (p56-HCK/p59-HCK) (Hemopoietic cell kinase) (B-cell/myeloid kinase) (BMK) Length = 523 Score = 35.4 bits (80), Expect = 0.12 Identities = 20/45 (44%), Positives = 29/45 (64%) Frame = -2 Query: 558 IGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAAN 424 I + APE I+ FG+ + KSDV+SFG+LL+E+ R P +N Sbjct: 418 IKWTAPEAIN--FGSFTIKSDVWSFGILLMEIVTYGRIPYPGMSN 460
>SPKA_SYNY3 (Q9FAB3) Serine/threonine-protein kinase A (EC 2.7.11.1)| Length = 521 Score = 35.4 bits (80), Expect = 0.12 Identities = 26/109 (23%), Positives = 51/109 (46%) Frame = -2 Query: 579 SRALRGTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAANSSQSYYPS 400 ++A GT+ Y +PE + + S+SD+YS G+++ EM G P+ +S +Y + Sbjct: 185 TQAFMGTLAYCSPEQMEGK--ELDSRSDIYSLGVMMYEMLTGEMPLFPD-NSSFGGWYEA 241 Query: 399 WVYDKLTAPVVDAVCPVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVI 253 + K P ++ +++ L + + C+ RP +VI Sbjct: 242 HHHTK--------PHPFSARYKIPASLEALVMNCLAKSPKGRPQSVDVI 282
>FGFR1_DROME (Q07407) Fibroblast growth factor receptor homolog 1 precursor (EC| 2.7.10.1) (Protein heartless) Length = 729 Score = 35.4 bits (80), Expect = 0.12 Identities = 26/106 (24%), Positives = 49/106 (46%) Frame = -2 Query: 558 IGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAANSSQSYYPSWVYDKLT 379 I ++APE + F SKSDV+S+G+LL E+ + P ++ + Y ++ Sbjct: 597 IKWMAPESLQEKF--YDSKSDVWSYGILLWEIMTYGQQPYPTIMSAEELYTYLMSGQRME 654 Query: 378 APVVDAVCPVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVIDMLE 241 P A C + + I+ C + DRP +E+++ ++ Sbjct: 655 KP---AKCSM--------NIYILMRQCWHFNADDRPPFTEIVEYMD 689
>M3KSL_DROME (Q95UN8) Mitogen-activated protein kinase kinase kinase (EC| 2.7.11.25) (Mixed lineage kinase) (dMLK) (Protein slipper) Length = 1161 Score = 35.4 bits (80), Expect = 0.12 Identities = 34/108 (31%), Positives = 46/108 (42%) Frame = -2 Query: 564 GTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAANSSQSYYPSWVYDK 385 GT ++ PE+IS S S SDV+S+G+LL E+ G P S + Sbjct: 307 GTYAWMPPEVISVS--TYSKFSDVWSYGVLLWELITGE---TPYKGFDPLSVAYGVAVNT 361 Query: 384 LTAPVVDAVCPVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVIDMLE 241 LT P + CP + L K C Q H RP E++ LE Sbjct: 362 LTLP-IPKTCP-ETWGALMKS-------CWQTDPHKRPGFKEILKQLE 400
>LYN_RAT (Q07014) Tyrosine-protein kinase Lyn (EC 2.7.10.2)| Length = 511 Score = 35.4 bits (80), Expect = 0.12 Identities = 26/57 (45%), Positives = 32/57 (56%), Gaps = 7/57 (12%) Frame = -2 Query: 558 IGYIAPEMISRSFGAISSKSDVYSFGMLLLEMA-------GGRRNADPNAANSSQSY 409 I + APE I+ FG + KSDV+SFG+LL E+ GR NAD A SQ Y Sbjct: 406 IKWTAPEAIN--FGCFTIKSDVWSFGILLYEIVTYGKIPYPGRTNADVMTA-LSQGY 459
>JIL1_DROME (Q9V3I5) Chromosomal serine/threonine-protein kinase JIL-1 (EC| 2.7.11.1) Length = 1207 Score = 35.4 bits (80), Expect = 0.12 Identities = 29/109 (26%), Positives = 44/109 (40%), Gaps = 3/109 (2%) Frame = -2 Query: 567 RGTIGYIAPEMIS-RSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAANSSQSYYPSWVY 391 R T+ Y PEM++ + S D+Y G L M G R P N + + + Sbjct: 777 RYTLDYAPPEMLADANLVTYSPAVDIYGLGATLYTMLVGHR---PYRQNEDDVDHSAAAH 833 Query: 390 DKLTAPVVDAVCPVASMHELEKKLCIVGL--WCIQMKSHDRPTMSEVID 250 +L + SM L WC+Q DRPT+S+++D Sbjct: 834 HELRKRMRRGTFNQRSMRWESASPAFRHLVSWCLQRDPADRPTLSDILD 882
>HCK_HUMAN (P08631) Tyrosine-protein kinase HCK (EC 2.7.10.2)| (p59-HCK/p60-HCK) (Hemopoietic cell kinase) Length = 525 Score = 35.4 bits (80), Expect = 0.12 Identities = 20/45 (44%), Positives = 29/45 (64%) Frame = -2 Query: 558 IGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAAN 424 I + APE I+ FG+ + KSDV+SFG+LL+E+ R P +N Sbjct: 420 IKWTAPEAIN--FGSFTIKSDVWSFGILLMEIVTYGRIPYPGMSN 462
>FYN_XIPHE (P27446) Proto-oncogene tyrosine-protein kinase FYN (EC 2.7.10.2)| (P59-FYN) Length = 536 Score = 35.4 bits (80), Expect = 0.12 Identities = 36/118 (30%), Positives = 51/118 (43%) Frame = -2 Query: 558 IGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAANSSQSYYPSWVYDKLT 379 I + APE + +G + KSDV+SFG+LL E+ R P N Y ++ Sbjct: 429 IKWTAPE--AALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGY-RMP 485 Query: 378 APVVDAVCPVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVIDMLEGGFDGLQMPSRP 205 P CP AS+HEL L C + +RPT + LE F + +P Sbjct: 486 CP---QDCP-ASLHELM-------LQCWKKDPEERPTFEYLQAFLEDYFTATEPQYQP 532
>CTR1_ARATH (Q05609) Serine/threonine-protein kinase CTR1 (EC 2.7.11.1)| Length = 821 Score = 35.4 bits (80), Expect = 0.12 Identities = 18/44 (40%), Positives = 30/44 (68%) Frame = -2 Query: 591 SFVPSRALRGTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMA 460 +F+ S++ GT ++APE++ + KSDVYSFG++L E+A Sbjct: 704 TFLSSKSAAGTPEWMAPEVLRDE--PSNEKSDVYSFGVILWELA 745
>HCK_RAT (P50545) Tyrosine-protein kinase HCK (EC 2.7.10.2) (p56-HCK)| (Hemopoietic cell kinase) Length = 502 Score = 35.4 bits (80), Expect = 0.12 Identities = 20/45 (44%), Positives = 29/45 (64%) Frame = -2 Query: 558 IGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAAN 424 I + APE I+ FG+ + KSDV+SFG+LL+E+ R P +N Sbjct: 397 IKWTAPEAIN--FGSFTIKSDVWSFGILLMEIVTYGRIPYPGMSN 439
>SCK2_SCHPO (Q10364) Serine/threonine-protein kinase sck2 (EC 2.7.11.1)| Length = 646 Score = 35.0 bits (79), Expect = 0.16 Identities = 24/69 (34%), Positives = 35/69 (50%) Frame = -2 Query: 579 SRALRGTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAANSSQSYYPS 400 +R GT Y+APE+I G D +S G+LL EM G P A+++Q Y + Sbjct: 424 TRTFCGTTDYLAPEVILDEAG-YDMMVDFWSLGVLLYEMTCG---WSPFYADNTQQLYKN 479 Query: 399 WVYDKLTAP 373 V+ K+ P Sbjct: 480 IVFGKVRFP 488
>LCK_AOTNA (Q5PXS1) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) Length = 508 Score = 35.0 bits (79), Expect = 0.16 Identities = 33/118 (27%), Positives = 50/118 (42%) Frame = -2 Query: 558 IGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAANSSQSYYPSWVYDKLT 379 I + APE I+ +G + KSDV+SFG+LL E+ R P N Y ++ Sbjct: 403 IKWTAPEAIN--YGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGY-RMV 459 Query: 378 APVVDAVCPVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVIDMLEGGFDGLQMPSRP 205 P CP H + + C + + DRPT + +LE F + +P Sbjct: 460 RP---DNCPEELYHLM--------MLCWKERPEDRPTFDYLRSVLEDFFTATEGQYQP 506
>GPRK2_DROME (P32866) G protein-coupled receptor kinase 2 (EC 2.7.11.16)| Length = 714 Score = 35.0 bits (79), Expect = 0.16 Identities = 19/38 (50%), Positives = 24/38 (63%) Frame = -2 Query: 564 GTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGR 451 GT+GY+APE+I A S D +SFG LL EM G+ Sbjct: 471 GTVGYMAPEVIDNEKYAFS--PDWFSFGCLLYEMIEGQ 506
>PKPA_PHYBL (Q01577) Serine/threonine-protein kinase pkpA (EC 2.7.11.1)| Length = 613 Score = 35.0 bits (79), Expect = 0.16 Identities = 18/37 (48%), Positives = 23/37 (62%) Frame = -2 Query: 564 GTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGG 454 GT ++APEM + K D+Y+FGM LLEMA G Sbjct: 175 GTPEFMAPEMYEEQ--GYNEKVDIYAFGMCLLEMATG 209
>M3K6_HUMAN (O95382) Mitogen-activated protein kinase kinase kinase 6 (EC| 2.7.11.25) Length = 1011 Score = 35.0 bits (79), Expect = 0.16 Identities = 15/38 (39%), Positives = 24/38 (63%) Frame = -2 Query: 564 GTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGR 451 GT+ Y+APE+I + +D++S G ++EMA GR Sbjct: 532 GTLQYMAPEIIDQGPRGYGKAADIWSLGCTVIEMATGR 569
>M3K4_MOUSE (O08648) Mitogen-activated protein kinase kinase kinase 4 (EC| 2.7.11.25) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4) Length = 1597 Score = 35.0 bits (79), Expect = 0.16 Identities = 16/40 (40%), Positives = 28/40 (70%), Gaps = 1/40 (2%) Frame = -2 Query: 564 GTIGYIAPEMISRSFGAISSK-SDVYSFGMLLLEMAGGRR 448 GT Y+APE+I+R+ G + +D++S G +++EM G+R Sbjct: 1493 GTAAYMAPEVITRAKGEGHGRAADIWSLGCVVIEMVTGKR 1532
>EPHB1_CHICK (Q07494) Ephrin type-B receptor 1 (EC 2.7.10.1) (Tyrosine-protein| kinase receptor EPH-2) (Tyrosine kinase CEK6 receptor) (Fragment) Length = 984 Score = 35.0 bits (79), Expect = 0.16 Identities = 32/107 (29%), Positives = 56/107 (52%), Gaps = 1/107 (0%) Frame = -2 Query: 558 IGYIAPEMISRSFGAISSKSDVYSFGMLLLE-MAGGRRNADPNAANSSQSYYPSWVYDKL 382 + + APE I+ + +S SDV+S+G+++ E M+ G R P S+Q + D Sbjct: 788 VRWTAPEAIA--YRKFTSASDVWSYGIVMWEVMSFGER---PYWDMSNQDVINAIEQDYR 842 Query: 381 TAPVVDAVCPVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVIDMLE 241 P +D CP A++H+L L C Q + RP ++E+++ L+ Sbjct: 843 LPPPMD--CP-AALHQLM-------LDCWQKDRNTRPRLAEIVNTLD 879
>FGR_MOUSE (P14234) Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2)| (P55-FGR) (C-FGR) Length = 517 Score = 35.0 bits (79), Expect = 0.16 Identities = 35/126 (27%), Positives = 54/126 (42%) Frame = -2 Query: 582 PSRALRGTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAANSSQSYYP 403 P + + I + APE + FG + KSDV+SFG+LL E+ R P N Sbjct: 402 PQQGTKFPIKWTAPE--AALFGRFTVKSDVWSFGILLTELITKGRVPYPGMNNREVLEQV 459 Query: 402 SWVYDKLTAPVVDAVCPVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVIDMLEGGFDGL 223 Y P CP AS++E+ ++ W ++ +RPT + LE F Sbjct: 460 EHGYHMPCPP----GCP-ASLYEVMEQ-----AW--RLDPEERPTFEYLQSFLEDYFTST 507 Query: 222 QMPSRP 205 + +P Sbjct: 508 EPQYQP 513
>EPA4B_XENLA (Q91694) Ephrin type-A receptor 4-B precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor PAG) (Pagliaccio) Length = 985 Score = 35.0 bits (79), Expect = 0.16 Identities = 33/107 (30%), Positives = 53/107 (49%), Gaps = 1/107 (0%) Frame = -2 Query: 558 IGYIAPEMISRSFGAISSKSDVYSFGMLLLE-MAGGRRNADPNAANSSQSYYPSWVYDKL 382 I + APE I+ + +S SDV+S+G+++ E M+ G R P S+Q + Sbjct: 787 IRWTAPEAIA--YRKFTSASDVWSYGIVMWEVMSYGER---PYWDMSNQDVIKAIEEGYR 841 Query: 381 TAPVVDAVCPVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVIDMLE 241 P +D CP+A +H+L L C Q DRP +++ ML+ Sbjct: 842 LPPPMD--CPIA-LHQLM-------LDCWQKDRSDRPKFGQIVSMLD 878
>M3K4_HUMAN (Q9Y6R4) Mitogen-activated protein kinase kinase kinase 4 (EC| 2.7.11.25) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4) (MAP three kinase 1) Length = 1607 Score = 35.0 bits (79), Expect = 0.16 Identities = 16/40 (40%), Positives = 28/40 (70%), Gaps = 1/40 (2%) Frame = -2 Query: 564 GTIGYIAPEMISRSFGAISSK-SDVYSFGMLLLEMAGGRR 448 GT Y+APE+I+R+ G + +D++S G +++EM G+R Sbjct: 1503 GTAAYMAPEVITRAKGEGHGRAADIWSLGCVVIEMVTGKR 1542
>GCN2_SCHPO (Q9HGN1) Serine/threonine-protein kinase gcn2 (EC 2.7.11.1)| Length = 1576 Score = 35.0 bits (79), Expect = 0.16 Identities = 17/35 (48%), Positives = 24/35 (68%), Gaps = 1/35 (2%) Frame = -2 Query: 564 GTIGYIAPEMISRSFGA-ISSKSDVYSFGMLLLEM 463 GT Y+APE++SR G +K D+YS G++L EM Sbjct: 822 GTALYVAPELLSRRNGVRYDAKVDMYSLGIILFEM 856 Score = 34.3 bits (77), Expect = 0.28 Identities = 15/34 (44%), Positives = 22/34 (64%) Frame = -2 Query: 555 GYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGG 454 G PE+ SF A S K+D++ FG+L+L+M G Sbjct: 425 GLYPPEVSESSFAAASRKTDIWCFGLLVLQMLCG 458
>FYN_HUMAN (P06241) Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2)| (p59-Fyn) (Protooncogene Syn) (SLK) Length = 536 Score = 35.0 bits (79), Expect = 0.16 Identities = 34/118 (28%), Positives = 51/118 (43%) Frame = -2 Query: 558 IGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAANSSQSYYPSWVYDKLT 379 I + APE + +G + KSDV+SFG+LL E+ R P N Y ++ Sbjct: 429 IKWTAPE--AALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGY-RMP 485 Query: 378 APVVDAVCPVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVIDMLEGGFDGLQMPSRP 205 P CP+ S+HEL + C + +RPT + LE F + +P Sbjct: 486 CP---QDCPI-SLHELM-------IHCWKKDPEERPTFEYLQSFLEDYFTATEPQYQP 532
>YES_AVISY (P00527) Tyrosine-protein kinase transforming protein YES (EC| 2.7.10.2) (Fragment) Length = 528 Score = 34.7 bits (78), Expect = 0.21 Identities = 34/109 (31%), Positives = 47/109 (43%) Frame = -2 Query: 558 IGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAANSSQSYYPSWVYDKLT 379 I + APE + +G + KSDV+SFG+LL E+ R P N Y ++ Sbjct: 426 IKWTAPE--AALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMVNREVLEQVERGY-RMP 482 Query: 378 APVVDAVCPVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVIDMLEGGF 232 P CP S+HEL K C + +RPT + LE F Sbjct: 483 CP---QGCP-ESLHELMK-------LCWKKDPDERPTFEYIQSFLEDYF 520
>FYN_MOUSE (P39688) Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2)| (p59-Fyn) Length = 533 Score = 34.7 bits (78), Expect = 0.21 Identities = 34/118 (28%), Positives = 51/118 (43%) Frame = -2 Query: 558 IGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAANSSQSYYPSWVYDKLT 379 I + APE + +G + KSDV+SFG+LL E+ R P N Y ++ Sbjct: 426 IKWTAPE--AALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGY-RMP 482 Query: 378 APVVDAVCPVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVIDMLEGGFDGLQMPSRP 205 P CP+ S+HEL + C + +RPT + LE F + +P Sbjct: 483 CP---QDCPI-SLHELM-------IHCWKKDPEERPTFEYLQGFLEDYFTATEPQYQP 529
>FYN_CHICK (Q05876) Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2)| (p59-Fyn) Length = 533 Score = 34.7 bits (78), Expect = 0.21 Identities = 34/118 (28%), Positives = 51/118 (43%) Frame = -2 Query: 558 IGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAANSSQSYYPSWVYDKLT 379 I + APE + +G + KSDV+SFG+LL E+ R P N Y ++ Sbjct: 426 IKWTAPE--AALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGY-RMP 482 Query: 378 APVVDAVCPVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVIDMLEGGFDGLQMPSRP 205 P CP+ S+HEL + C + +RPT + LE F + +P Sbjct: 483 CP---QDCPI-SLHELM-------IHCWKKDPEERPTFEYLQGFLEDYFTATEPQYQP 529
>M3K5_MOUSE (O35099) Mitogen-activated protein kinase kinase kinase 5 (EC| 2.7.11.25) (MAPK/ERK kinase kinase 5) (MEK kinase 5) (MEKK 5) (Apoptosis signal-regulating kinase 1) (ASK-1) Length = 1380 Score = 34.7 bits (78), Expect = 0.21 Identities = 14/38 (36%), Positives = 24/38 (63%) Frame = -2 Query: 564 GTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGR 451 GT+ Y+APE+I + +D++S G ++EMA G+ Sbjct: 848 GTLQYMAPEIIDKGPRGYGKAADIWSLGCTIIEMATGK 885
>M3K5_HUMAN (Q99683) Mitogen-activated protein kinase kinase kinase 5 (EC| 2.7.11.25) (MAPK/ERK kinase kinase 5) (MEK kinase 5) (MEKK 5) (Apoptosis signal-regulating kinase 1) (ASK-1) Length = 1374 Score = 34.7 bits (78), Expect = 0.21 Identities = 14/38 (36%), Positives = 24/38 (63%) Frame = -2 Query: 564 GTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGR 451 GT+ Y+APE+I + +D++S G ++EMA G+ Sbjct: 841 GTLQYMAPEIIDKGPRGYGKAADIWSLGCTIIEMATGK 878
>KIN31_CAEEL (P34265) Probable tyrosine-protein kinase kin-31 (EC 2.7.10.2)| Length = 437 Score = 34.7 bits (78), Expect = 0.21 Identities = 31/112 (27%), Positives = 49/112 (43%), Gaps = 3/112 (2%) Frame = -2 Query: 567 RGTIGYIAPEMIS--RSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAANSSQSYYPSWV 394 RGTI + PE S R S K+DV+++G+L E+ N+ YP Sbjct: 279 RGTIYQLHPETKSPIRWLAVCSQKTDVWAYGILCWEIF-----------NNGAEPYPGLT 327 Query: 393 YDKLTAPVVDAV-CPVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVIDMLE 241 +++ V D P + E + + C +DRPTMS+V +L+ Sbjct: 328 ANEVAKQVTDGYRMPPHQLAAPEVQALMTR--CCAENPNDRPTMSDVAQILQ 377
>PAK6_HUMAN (Q9NQU5) Serine/threonine-protein kinase PAK 6 (EC 2.7.11.1)| (p21-activated kinase 6) (PAK-6) (PAK-5) Length = 681 Score = 34.7 bits (78), Expect = 0.21 Identities = 20/45 (44%), Positives = 32/45 (71%), Gaps = 1/45 (2%) Frame = -2 Query: 585 VPSR-ALRGTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGG 454 VP R +L GT ++APE+ISRS A ++ D++S G++++EM G Sbjct: 555 VPKRKSLVGTPYWMAPEVISRSLYA--TEVDIWSLGIMVIEMVDG 597
>HCK_MACFA (Q95M30) Tyrosine-protein kinase HCK (EC 2.7.10.2) (p56-HCK)| (Hemopoietic cell kinase) Length = 503 Score = 34.7 bits (78), Expect = 0.21 Identities = 20/45 (44%), Positives = 29/45 (64%) Frame = -2 Query: 558 IGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAAN 424 I + APE I+ FG+ + KSDV+SFG+LL+E+ R P +N Sbjct: 398 IKWTAPEAIN--FGSSTIKSDVWSFGILLMEIVTYGRIPYPGMSN 440
>EPHB1_RAT (P09759) Ephrin type-B receptor 1 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EPH-2) (ELK) Length = 984 Score = 34.7 bits (78), Expect = 0.21 Identities = 32/107 (29%), Positives = 55/107 (51%), Gaps = 1/107 (0%) Frame = -2 Query: 558 IGYIAPEMISRSFGAISSKSDVYSFGMLLLE-MAGGRRNADPNAANSSQSYYPSWVYDKL 382 + + APE I+ + +S SDV+S+G+++ E M+ G R P S+Q + D Sbjct: 788 VRWTAPEAIA--YRKFTSASDVWSYGIVMWEVMSFGER---PYWDMSNQDVINAIEQDYR 842 Query: 381 TAPVVDAVCPVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVIDMLE 241 P +D CP A++H+L L C Q + RP +E+++ L+ Sbjct: 843 LPPPMD--CP-AALHQLM-------LDCWQKDRNSRPRFAEIVNTLD 879
>EPHB1_HUMAN (P54762) Ephrin type-B receptor 1 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EPH-2) (NET) (HEK6) (ELK) Length = 984 Score = 34.7 bits (78), Expect = 0.21 Identities = 32/107 (29%), Positives = 55/107 (51%), Gaps = 1/107 (0%) Frame = -2 Query: 558 IGYIAPEMISRSFGAISSKSDVYSFGMLLLE-MAGGRRNADPNAANSSQSYYPSWVYDKL 382 + + APE I+ + +S SDV+S+G+++ E M+ G R P S+Q + D Sbjct: 788 VRWTAPEAIA--YRKFTSASDVWSYGIVMWEVMSFGER---PYWDMSNQDVINAIEQDYR 842 Query: 381 TAPVVDAVCPVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVIDMLE 241 P +D CP A++H+L L C Q + RP +E+++ L+ Sbjct: 843 LPPPMD--CP-AALHQLM-------LDCWQKDRNSRPRFAEIVNTLD 879
>LIMK1_RAT (P53669) LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1)| Length = 647 Score = 34.7 bits (78), Expect = 0.21 Identities = 25/55 (45%), Positives = 35/55 (63%), Gaps = 5/55 (9%) Frame = -2 Query: 582 PSRALRGTIG----YIAPEMIS-RSFGAISSKSDVYSFGMLLLEMAGGRRNADPN 433 P R R T+ ++APEMI+ RS+ K DV+SFG++L E+ GR NADP+ Sbjct: 501 PDRKKRYTVVGNPYWMAPEMINGRSY---DEKVDVFSFGIVLCEII-GRVNADPD 551
>LIMK1_MOUSE (P53668) LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1) (KIZ-1)| Length = 647 Score = 34.7 bits (78), Expect = 0.21 Identities = 25/55 (45%), Positives = 35/55 (63%), Gaps = 5/55 (9%) Frame = -2 Query: 582 PSRALRGTIG----YIAPEMIS-RSFGAISSKSDVYSFGMLLLEMAGGRRNADPN 433 P R R T+ ++APEMI+ RS+ K DV+SFG++L E+ GR NADP+ Sbjct: 501 PDRKKRYTVVGNPYWMAPEMINGRSY---DEKVDVFSFGIVLCEII-GRVNADPD 551
>LIMK1_HUMAN (P53667) LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1)| Length = 647 Score = 34.7 bits (78), Expect = 0.21 Identities = 25/55 (45%), Positives = 35/55 (63%), Gaps = 5/55 (9%) Frame = -2 Query: 582 PSRALRGTIG----YIAPEMIS-RSFGAISSKSDVYSFGMLLLEMAGGRRNADPN 433 P R R T+ ++APEMI+ RS+ K DV+SFG++L E+ GR NADP+ Sbjct: 501 PDRKKRYTVVGNPYWMAPEMINGRSY---DEKVDVFSFGIVLCEII-GRVNADPD 551
>WNK2_HUMAN (Q9Y3S1) Serine/threonine-protein kinase WNK2 (EC 2.7.11.1)| (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2) Length = 2297 Score = 34.7 bits (78), Expect = 0.21 Identities = 36/132 (27%), Positives = 59/132 (44%) Frame = -2 Query: 579 SRALRGTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAANSSQSYYPS 400 ++++ GT ++APEM + DVY+FGM +LEMA + S+ + Sbjct: 354 AKSVIGTPEFMAPEMYEEHY---DESVDVYAFGMCMLEMA-------TSEYPYSECQNAA 403 Query: 399 WVYDKLTAPVVDAVCPVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVIDMLEGGFDGLQ 220 +Y K+T + A +H+ E K I+G CI +R E+ D+L F Sbjct: 404 QIYRKVTCGIKPA--SFEKVHDPEIKE-IIG-ECICKNKEER---YEIKDLLSHAFFAED 456 Query: 219 MPSRPFFCDDDH 184 R ++DH Sbjct: 457 TGVRVELAEEDH 468
>FYN_XENLA (P13406) Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2)| (p59-Fyn) Length = 536 Score = 34.7 bits (78), Expect = 0.21 Identities = 35/118 (29%), Positives = 51/118 (43%) Frame = -2 Query: 558 IGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAANSSQSYYPSWVYDKLT 379 I + APE + +G + KSDV+SFG+LL E+ R P N Y ++ Sbjct: 429 IKWTAPE--AALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGY-RMP 485 Query: 378 APVVDAVCPVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVIDMLEGGFDGLQMPSRP 205 P CP+ S+HEL L C + +RPT + LE F + +P Sbjct: 486 CP---QDCPI-SLHELM-------LNCWKKDPEERPTFEYLQGFLEDYFTATEPQYQP 532
>CPK11_ARATH (O22932) CBL-interacting serine/threonine-protein kinase 11 (EC| 2.7.11.1) (SOS2-like protein kinase PKS5) (SOS-interacting protein 4) (SNF1-related kinase 3.22) Length = 435 Score = 34.7 bits (78), Expect = 0.21 Identities = 24/66 (36%), Positives = 35/66 (53%), Gaps = 7/66 (10%) Frame = -2 Query: 570 LRGTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEM-AGGRRNADPNAANSSQSYY---- 406 L GT Y+APE++S+ G +K DV+S G++L + AG DPN N + Y Sbjct: 182 LCGTPAYVAPEILSKK-GYEGAKVDVWSCGIVLFVLVAGYLPFNDPNVMNMYKKIYKGEY 240 Query: 405 --PSWV 394 P W+ Sbjct: 241 RFPRWM 246
>SRC64_DROME (P00528) Tyrosine-protein kinase Src64B (EC 2.7.10.2) (Dsrc64)| Length = 552 Score = 34.3 bits (77), Expect = 0.28 Identities = 17/42 (40%), Positives = 27/42 (64%) Frame = -2 Query: 588 FVPSRALRGTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEM 463 + P + R + + APE I +G S KSDV+S+G+LL+E+ Sbjct: 434 YCPKQGSRFPVKWTAPEAII--YGKFSIKSDVWSYGILLMEL 473
>IRAK1_HUMAN (P51617) Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1)| (IRAK-1) Length = 712 Score = 34.3 bits (77), Expect = 0.28 Identities = 16/53 (30%), Positives = 31/53 (58%) Frame = -2 Query: 579 SRALRGTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAANS 421 ++ +RGT+ Y+ E I G ++ +D +SFG+++LE G+R + A + Sbjct: 381 TQTVRGTLAYLPEEYIKT--GRLAVDTDTFSFGVVVLETLAGQRAVKTHGART 431
>M3K2_ARATH (Q9FZ36) Mitogen-activated protein kinase kinase kinase 2 (EC| 2.7.11.25) (Arabidospsis NPK1-related protein kinase 2) Length = 651 Score = 34.3 bits (77), Expect = 0.28 Identities = 46/186 (24%), Positives = 81/186 (43%), Gaps = 12/186 (6%) Frame = -2 Query: 579 SRALRGTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAANSSQSYYPS 400 +++++GT ++APE+I ++ + S+ D++S G ++EM G+ + ++ Sbjct: 230 AKSMKGTPYWMAPEVILQTGHSFSA--DIWSVGCTVIEMVTGKAPWSQQYKEIAAIFHIG 287 Query: 399 WVYDKLTAPVVDAVCPVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVIDMLEGGFDGLQ 220 K P+ D + A+ L+ C+Q + + RPT SE++ G Q Sbjct: 288 TT--KSHPPIPDNISSDANDFLLK---------CLQQEPNLRPTASELLK--HPFVTGKQ 334 Query: 219 MPSRPFFCDDDHTAVPDS--YPLLSELTEI-----SEEDDE*HMC-----VCVCDLMSQV 76 S D T+ D+ PL SELT I S DD +C C + Sbjct: 335 KES----ASKDLTSFMDNSCSPLPSELTNITSYQTSTSDDVGDICNLGSLTCTLAFPEKS 390 Query: 75 LRNNLL 58 ++NN L Sbjct: 391 IQNNSL 396
>M3K1_HUMAN (Q13233) Mitogen-activated protein kinase kinase kinase 1 (EC| 2.7.11.25) (MAPK/ERK kinase kinase 1) (MEK kinase 1) (MEKK 1) (Fragment) Length = 1495 Score = 33.9 bits (76), Expect = 0.36 Identities = 29/109 (26%), Positives = 54/109 (49%), Gaps = 3/109 (2%) Frame = -2 Query: 570 LRGTIGYIAPEMI-SRSFGAISSKSDVYSFGMLLLEMAGGRR--NADPNAANSSQSYYPS 400 L GTI ++APE++ + +G DV+S G ++EMA + NA+ ++ + + + Sbjct: 1392 LLGTIAFMAPEVLRGQQYGR---SCDVWSVGCAIIEMACAKPPWNAEKHSNHLALIFK-- 1446 Query: 399 WVYDKLTAPVVDAVCPVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVI 253 + TAP + + L L V L C++++ DRP E++ Sbjct: 1447 -IASATTAPSIPS--------HLSPGLRDVALRCLELQPQDRPPSRELL 1486
>LRRK1_MOUSE (Q3UHC2) Leucine-rich repeat serine/threonine-protein kinase 1 (EC| 2.7.11.1) Length = 2014 Score = 33.9 bits (76), Expect = 0.36 Identities = 18/43 (41%), Positives = 26/43 (60%) Frame = -2 Query: 570 LRGTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNA 442 + GT GY APE+ R K D++S+GM+L E+ G+R A Sbjct: 1424 VEGTPGYQAPEIRPRI--VYDEKVDMFSYGMVLYELLSGQRPA 1464
>MEK2_CAEEL (Q10664) Dual specificity mitogen-activated protein kinase kinase| mek-2 (EC 2.7.12.2) (MAP kinase kinase mek-2) Length = 387 Score = 33.9 bits (76), Expect = 0.36 Identities = 18/38 (47%), Positives = 26/38 (68%) Frame = -2 Query: 564 GTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGR 451 GT Y+APE ++ S ISS D++SFG+ L+E+ GR Sbjct: 230 GTRSYMAPERLTGSHYTISS--DIWSFGLSLVELLIGR 265
>M3K1_RAT (Q62925) Mitogen-activated protein kinase kinase kinase 1 (EC| 2.7.11.25) (MAPK/ERK kinase kinase 1) (MEK kinase 1) (MEKK 1) Length = 1493 Score = 33.9 bits (76), Expect = 0.36 Identities = 29/109 (26%), Positives = 54/109 (49%), Gaps = 3/109 (2%) Frame = -2 Query: 570 LRGTIGYIAPEMI-SRSFGAISSKSDVYSFGMLLLEMAGGRR--NADPNAANSSQSYYPS 400 L GTI ++APE++ + +G DV+S G ++EMA + NA+ ++ + + + Sbjct: 1390 LLGTIAFMAPEVLRGQQYGR---SCDVWSVGCAIIEMACAKPPWNAEKHSNHLALIFK-- 1444 Query: 399 WVYDKLTAPVVDAVCPVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVI 253 + TAP + + L L V L C++++ DRP E++ Sbjct: 1445 -IASATTAPSIPS--------HLSPGLRDVALRCLELQPQDRPPSRELL 1484
>FGFR2_DROME (Q09147) Fibroblast growth factor receptor homolog 2 precursor (EC| 2.7.10.1) (Protein breathless) (dFGF-R1) Length = 1052 Score = 33.9 bits (76), Expect = 0.36 Identities = 37/148 (25%), Positives = 64/148 (43%), Gaps = 2/148 (1%) Frame = -2 Query: 558 IGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAANSSQSYYPSWVYDKLT 379 I ++APE + S+SDV+S+G+LL E+ P+ ++ + Y ++ Sbjct: 905 IKWMAPESLQEK--KYDSQSDVWSYGVLLWEIMTYGDQPYPHILSAEELYSYLITGQRME 962 Query: 378 APVVDAVCPVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVIDMLEGGFDGL--QMPSRP 205 P A C + + +V C +S RPT +E+++ FDG+ Q S P Sbjct: 963 KP---AKCSL--------NIYVVMRQCWHFESCARPTFAELVE----SFDGILQQASSNP 1007 Query: 204 FFCDDDHTAVPDSYPLLSELTEISEEDD 121 + + S P+L +EDD Sbjct: 1008 -----NDAYLDLSMPMLETPPSSGDEDD 1030
>LRRK1_HUMAN (Q38SD2) Leucine-rich repeat serine/threonine-protein kinase 1 (EC| 2.7.11.1) Length = 2038 Score = 33.9 bits (76), Expect = 0.36 Identities = 18/43 (41%), Positives = 26/43 (60%) Frame = -2 Query: 570 LRGTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNA 442 + GT GY APE+ R K D++S+GM+L E+ G+R A Sbjct: 1447 VEGTPGYQAPEIRPRI--VYDEKVDMFSYGMVLYELLSGQRPA 1487
>VAB1_CAEEL (O61460) Ephrin receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein| kinase Eph receptor) (Variable abnormal protein 1) Length = 1122 Score = 33.9 bits (76), Expect = 0.36 Identities = 24/102 (23%), Positives = 47/102 (46%) Frame = -2 Query: 558 IGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAANSSQSYYPSWVYDKLT 379 + + APE I+ + SDV+SFG+++ E+ + + Y W K+ Sbjct: 894 VRWTAPEAITHR--KFTPSSDVWSFGVVIWEVC-----------SFGERPYWDWTNQKVI 940 Query: 378 APVVDAVCPVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVI 253 + V+ M + L + WC +M+ H+RPT ++++ Sbjct: 941 SEVMIGYRLPPPM-DCPMGLYRIAQWCWKMERHERPTFTQLL 981
>LCK_MOUSE (P06240) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK) Length = 508 Score = 33.9 bits (76), Expect = 0.36 Identities = 32/118 (27%), Positives = 50/118 (42%) Frame = -2 Query: 558 IGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAANSSQSYYPSWVYDKLT 379 I + APE I+ +G + KSDV+SFG+LL E+ R P N Y ++ Sbjct: 403 IKWTAPEAIN--YGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGY-RMV 459 Query: 378 APVVDAVCPVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVIDMLEGGFDGLQMPSRP 205 P CP H + + C + + DRPT + +L+ F + +P Sbjct: 460 RP---DNCPEELYHLM--------MLCWKERPEDRPTFDYLRSVLDDFFTATEGQYQP 506
>PTK6_HUMAN (Q13882) Tyrosine-protein kinase 6 (EC 2.7.10.2) (Breast tumor| kinase) (Tyrosine-protein kinase BRK) Length = 451 Score = 33.9 bits (76), Expect = 0.36 Identities = 20/43 (46%), Positives = 27/43 (62%) Frame = -2 Query: 552 YIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAAN 424 + APE +SR G S+KSDV+SFG+LL EM + P +N Sbjct: 353 WTAPEALSR--GHYSTKSDVWSFGILLHEMFSRGQVPYPGMSN 393
>SSK22_YEAST (P25390) Serine/threonine-protein kinase SSK22 (EC 2.7.11.1) (MAP| kinase kinase kinase SSK22) (Suppressor of sensor kinase 22) Length = 1331 Score = 33.9 bits (76), Expect = 0.36 Identities = 21/44 (47%), Positives = 28/44 (63%), Gaps = 3/44 (6%) Frame = -2 Query: 570 LRGTIGYIAPEMISRSFGAISSK---SDVYSFGMLLLEMAGGRR 448 + GT Y+APE IS S A+ K DV++ G ++LEMA GRR Sbjct: 1209 MMGTPMYMAPETISGS--AVKGKLGADDVWALGCVVLEMATGRR 1250
>ITK_MOUSE (Q03526) Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2)| (T-cell-specific kinase) (IL-2-inducible T-cell kinase) (Kinase EMT) (Kinase TLK) Length = 625 Score = 33.9 bits (76), Expect = 0.36 Identities = 30/115 (26%), Positives = 52/115 (45%) Frame = -2 Query: 588 FVPSRALRGTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAANSSQSY 409 + S + + + +PE+ S F SSKSDV+SFG+L+ E+ + N +NS Sbjct: 517 YTSSTGTKFPVKWASPEVFS--FSRYSSKSDVWSFGVLMWEVFSEGKIPYENRSNSE--- 571 Query: 408 YPSWVYDKLTAPVVDAVCPVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVIDML 244 V + ++ +AS H + + C + K DRP S+++ L Sbjct: 572 ----VVEDISTGFRLYKPRLASCHVYQ-----IMNHCWKEKPEDRPPFSQLLSQL 617
>YRK_CHICK (Q02977) Proto-oncogene tyrosine-protein kinase Yrk (EC 2.7.10.2)| (p60-Yrk) (Yes-related kinase) Length = 535 Score = 33.9 bits (76), Expect = 0.36 Identities = 34/118 (28%), Positives = 51/118 (43%) Frame = -2 Query: 558 IGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAANSSQSYYPSWVYDKLT 379 I + APE + FG + KSDV+SFG+LL E+ R P N Y ++ Sbjct: 428 IKWTAPE--AALFGKFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGY-RMQ 484 Query: 378 APVVDAVCPVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVIDMLEGGFDGLQMPSRP 205 P CP S+H+ V + C + + +RPT + LE F + +P Sbjct: 485 CP---GGCP-PSLHD-------VMVQCWKREPEERPTFEYLQSFLEDYFTATEPQYQP 531
>SRC_RAT (Q9WUD9) Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2)| (p60-Src) (c-Src) (pp60c-src) Length = 535 Score = 33.9 bits (76), Expect = 0.36 Identities = 32/118 (27%), Positives = 48/118 (40%) Frame = -2 Query: 558 IGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAANSSQSYYPSWVYDKLT 379 I + APE + +G + KSDV+SFG+LL E+ R P N V D++ Sbjct: 428 IKWTAPE--AALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNRE-------VLDQVE 478 Query: 378 APVVDAVCPVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVIDMLEGGFDGLQMPSRP 205 CP L +C C + + +RPT + LE F + +P Sbjct: 479 RG-YRMPCPPECPESLHDLMC----QCWRKEPEERPTFEYLQAFLEDYFTSTERQYQP 531
>WNK1_HUMAN (Q9H4A3) Serine/threonine-protein kinase WNK1 (EC 2.7.11.1)| (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1) (Kinase deficient protein) Length = 2382 Score = 33.5 bits (75), Expect = 0.47 Identities = 28/110 (25%), Positives = 55/110 (50%) Frame = -2 Query: 579 SRALRGTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAANSSQSYYPS 400 ++++ GT ++APEM + DVY+FGM +LEMA + S+ + Sbjct: 380 AKSVIGTPEFMAPEMYEEKY---DESVDVYAFGMCMLEMA-------TSEYPYSECQNAA 429 Query: 399 WVYDKLTAPVVDAVCPVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVID 250 +Y ++T+ V A ++ E+ K I G CI+ +R ++ ++++ Sbjct: 430 QIYRRVTSGVKPASFDKVAIPEV--KEIIEG--CIRQNKDERYSIKDLLN 475
>GCY3E_DROME (Q07553) Guanylate cyclase 32E precursor (EC 4.6.1.2)| Length = 1163 Score = 33.5 bits (75), Expect = 0.47 Identities = 17/33 (51%), Positives = 23/33 (69%), Gaps = 2/33 (6%) Frame = -2 Query: 549 IAPEMISRSF--GAISSKSDVYSFGMLLLEMAG 457 +APE++ ++ G S K DVYSFG+LL EM G Sbjct: 696 MAPELLRDAYRPGRGSQKGDVYSFGILLYEMIG 728
>HT1_ARATH (Q2MHE4) Serine/threonine-protein kinase HT1 (EC 2.7.11.1) (High| leaf temperature protein 1) Length = 390 Score = 33.5 bits (75), Expect = 0.47 Identities = 32/112 (28%), Positives = 46/112 (41%), Gaps = 4/112 (3%) Frame = -2 Query: 564 GTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAANSSQSYYPSW---- 397 GT ++APEMI + K DVYSFG++L E+ A Q P Sbjct: 248 GTYRWMAPEMIKEK--PYTRKVDVYSFGIVLWELT--------TALLPFQGMTPVQAAFA 297 Query: 396 VYDKLTAPVVDAVCPVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVIDMLE 241 V +K P + A C A H +++ C RP S ++ +LE Sbjct: 298 VAEKNERPPLPASCQPALAHLIKR--------CWSENPSKRPDFSNIVAVLE 341
>SRC_MOUSE (P05480) Neuronal proto-oncogene tyrosine-protein kinase Src (EC| 2.7.10.2) (p60-Src) (c-Src) (pp60c-src) Length = 540 Score = 33.5 bits (75), Expect = 0.47 Identities = 32/118 (27%), Positives = 48/118 (40%) Frame = -2 Query: 558 IGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAANSSQSYYPSWVYDKLT 379 I + APE + +G + KSDV+SFG+LL E+ R P N V D++ Sbjct: 433 IKWTAPE--AALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNRE-------VLDQVE 483 Query: 378 APVVDAVCPVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVIDMLEGGFDGLQMPSRP 205 CP L +C C + + +RPT + LE F + +P Sbjct: 484 RG-YRMPCPPECPESLHDLMC----QCWRKEPEERPTFEYLQAFLEDYFTSTEPQYQP 536
>KYK1_DICDI (P18160) Non-receptor tyrosine kinase spore lysis A (EC 2.7.10.2)| (Tyrosine-protein kinase 1) Length = 1584 Score = 33.5 bits (75), Expect = 0.47 Identities = 17/34 (50%), Positives = 22/34 (64%) Frame = -2 Query: 564 GTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEM 463 G I Y+APE+ S KSDVYS+GM+L E+ Sbjct: 1467 GCIPYMAPEVFKGDSN--SEKSDVYSYGMVLFEL 1498
>LCK_SAISC (Q95KR7) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) Length = 508 Score = 33.5 bits (75), Expect = 0.47 Identities = 34/118 (28%), Positives = 52/118 (44%) Frame = -2 Query: 558 IGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAANSSQSYYPSWVYDKLT 379 I + APE I+ +G + KSDV+SFG+L+ E+ R P N Y ++ Sbjct: 403 IKWTAPEAIN--YGTFTIKSDVWSFGILMTEIVTHGRIPYPGMTNPEVIQNLERGY-RMP 459 Query: 378 APVVDAVCPVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVIDMLEGGFDGLQMPSRP 205 P CP EL K + + C + + DRPT + +LE F + +P Sbjct: 460 RP---DNCP----EELYKLM----MQCWRERPDDRPTFDYLRSVLEDFFTATEGQYQP 506
>FES_HUMAN (P07332) Proto-oncogene tyrosine-protein kinase Fes/Fps (EC| 2.7.10.2) (C-Fes) Length = 822 Score = 33.5 bits (75), Expect = 0.47 Identities = 29/106 (27%), Positives = 48/106 (45%) Frame = -2 Query: 558 IGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAANSSQSYYPSWVYDKLT 379 + + APE ++ +G SS+SDV+SFG+LL E + PN +N + +L Sbjct: 724 VKWTAPEALN--YGRYSSESDVWSFGILLWETFSLGASPYPNLSNQQTREFVE-KGGRLP 780 Query: 378 APVVDAVCPVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVIDMLE 241 P +CP A +E+ C + RP+ S + L+ Sbjct: 781 CP---ELCPDAVFRLMEQ--------CWAYEPGQRPSFSTIYQELQ 815
>EPB1B_XENLA (Q91736) Ephrin type-B receptor 1-B (EC 2.7.10.1) (Tyrosine-protein| kinase receptor XELK) (Fragment) Length = 902 Score = 33.5 bits (75), Expect = 0.47 Identities = 32/107 (29%), Positives = 53/107 (49%), Gaps = 1/107 (0%) Frame = -2 Query: 558 IGYIAPEMISRSFGAISSKSDVYSFGMLLLE-MAGGRRNADPNAANSSQSYYPSWVYDKL 382 + + APE I + +S SDV+S+G+++ E M+ G R P S+Q + D Sbjct: 706 VRWTAPEAIR--YRKFTSASDVWSYGIVMWEVMSYGER---PYWDMSNQDVINAIEQDYR 760 Query: 381 TAPVVDAVCPVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVIDMLE 241 P +D CP A++H+L L C Q + RP E+++ L+ Sbjct: 761 LPPPMD--CP-AALHQLM-------LDCWQKDRNSRPRFGEIVNTLD 797
>RIPK1_MOUSE (Q60855) Receptor-interacting serine/threonine-protein kinase 1 (EC| 2.7.11.1) (Serine/threonine-protein kinase RIP) (Cell death protein RIP) (Receptor-interacting protein) Length = 656 Score = 33.5 bits (75), Expect = 0.47 Identities = 34/142 (23%), Positives = 58/142 (40%), Gaps = 7/142 (4%) Frame = -2 Query: 564 GTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAANSSQSYYPSWVYDK 385 GT+ Y+APE ++ + KSDVYSFG++L + ++ N + Q ++ Sbjct: 189 GTLYYMAPEHLNDINAKPTEKSDVYSFGIVLWAIF-AKKEPYENVICTEQFVICIKSGNR 247 Query: 384 LTAPVVDAVCPVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVIDMLEGGFDGLQMPSRP 205 + CP + +E+ C Q DRPT F G++ RP Sbjct: 248 PNVEEILEYCPREIISLMER--------CWQAIPEDRPT-----------FLGIEEEFRP 288 Query: 204 F-------FCDDDHTAVPDSYP 160 F + ++D ++ YP Sbjct: 289 FYLSHFEEYVEEDVASLKKEYP 310
>FES_FELCA (P14238) Proto-oncogene tyrosine-protein kinase FES/FPS (EC| 2.7.10.2) (C-FES) Length = 820 Score = 33.5 bits (75), Expect = 0.47 Identities = 29/106 (27%), Positives = 48/106 (45%) Frame = -2 Query: 558 IGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAANSSQSYYPSWVYDKLT 379 + + APE ++ +G SS+SDV+SFG+LL E + PN +N + +L Sbjct: 722 VKWTAPEALN--YGRYSSESDVWSFGILLWETFSLGASPYPNLSNQQTREFVE-KGGRLP 778 Query: 378 APVVDAVCPVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVIDMLE 241 P +CP A +E+ C + RP+ S + L+ Sbjct: 779 CP---ELCPDAVFRLMEQ--------CWAYEPGQRPSFSAIYQELQ 813
>WNK1_RAT (Q9JIH7) Serine/threonine-protein kinase WNK1 (EC 2.7.11.1)| (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1) Length = 2126 Score = 33.5 bits (75), Expect = 0.47 Identities = 28/110 (25%), Positives = 55/110 (50%) Frame = -2 Query: 579 SRALRGTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAANSSQSYYPS 400 ++++ GT ++APEM + DVY+FGM +LEMA + S+ + Sbjct: 380 AKSVIGTPEFMAPEMYEEKY---DESVDVYAFGMCMLEMA-------TSEYPYSECQNAA 429 Query: 399 WVYDKLTAPVVDAVCPVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVID 250 +Y ++T+ V A ++ E+ K I G CI+ +R ++ ++++ Sbjct: 430 QIYRRVTSGVKPASFDKVAIPEV--KEIIEG--CIRQNKDERYSIKDLLN 475
>SRC_AVIS2 (P15054) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 586 Score = 33.5 bits (75), Expect = 0.47 Identities = 32/115 (27%), Positives = 46/115 (40%) Frame = -2 Query: 558 IGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAANSSQSYYPSWVYDKLT 379 I + APE + +G + KSDV+SFG+LL E+ R P N V D++ Sbjct: 425 IKWTAPE--AALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNRE-------VLDQVE 475 Query: 378 APVVDAVCPVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVIDMLEGGFDGLQMP 214 CP L +C C + +RPT + LE F + P Sbjct: 476 RG-YRMPCPPECPESLHDLMC----QCWRKDPEERPTFEYLQAFLEDYFTSTEPP 525
>SRC_HUMAN (P12931) Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2)| (p60-Src) (c-Src) (pp60c-src) Length = 535 Score = 33.5 bits (75), Expect = 0.47 Identities = 32/118 (27%), Positives = 48/118 (40%) Frame = -2 Query: 558 IGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAANSSQSYYPSWVYDKLT 379 I + APE + +G + KSDV+SFG+LL E+ R P N V D++ Sbjct: 428 IKWTAPE--AALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNRE-------VLDQVE 478 Query: 378 APVVDAVCPVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVIDMLEGGFDGLQMPSRP 205 CP L +C C + + +RPT + LE F + +P Sbjct: 479 RG-YRMPCPPECPESLHDLMC----QCWRKEPEERPTFEYLQAFLEDYFTSTEPQYQP 531
>FES_FSVGA (P00542) Tyrosine-protein kinase transforming protein Fes (EC| 2.7.10.2) Length = 609 Score = 33.5 bits (75), Expect = 0.47 Identities = 29/106 (27%), Positives = 48/106 (45%) Frame = -2 Query: 558 IGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAANSSQSYYPSWVYDKLT 379 + + APE ++ +G SS+SDV+SFG+LL E + PN +N + +L Sbjct: 511 VKWTAPEALN--YGRYSSESDVWSFGILLWETFSLGASPYPNLSNQQTREFVE-KGGRLP 567 Query: 378 APVVDAVCPVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVIDMLE 241 P +CP A +E+ C + RP+ S + L+ Sbjct: 568 CP---ELCPDAVFRLMEQ--------CWAYEPGQRPSFSAIYQELQ 602
>CHK1_DROME (O61661) Serine/threonine-protein kinase grp (EC 2.7.11.1) (Protein| grapes) (Chk1 homolog) Length = 512 Score = 33.5 bits (75), Expect = 0.47 Identities = 16/56 (28%), Positives = 34/56 (60%) Frame = -2 Query: 564 GTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAANSSQSYYPSW 397 GT+ Y+APE++ +++ A +D++S G++L+ M G D + N ++ + +W Sbjct: 182 GTLPYVAPEVLQKAYHA--QPADLWSCGVILVTMLAGELPWDQPSTNCTE--FTNW 233
>WNK3_HUMAN (Q9BYP7) Serine/threonine-protein kinase WNK3 (EC 2.7.11.1)| (Protein kinase with no lysine 3) (Protein kinase, lysine-deficient 3) Length = 1743 Score = 33.5 bits (75), Expect = 0.47 Identities = 37/153 (24%), Positives = 66/153 (43%) Frame = -2 Query: 579 SRALRGTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAANSSQSYYPS 400 ++++ GT ++APEM + DVY+FGM +LEMA + S+ + Sbjct: 306 AKSVIGTPEFMAPEMYEEHY---DESVDVYAFGMCMLEMA-------TSEYPYSECQNAA 355 Query: 399 WVYDKLTAPVVDAVCPVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVIDMLEGGFDGLQ 220 +Y K+T+ + A + + E K I G CI+ +R ++ +++ Sbjct: 356 QIYRKVTSGIKPA--SFNKVTDPEVKEIIEG--CIRQNKSERLSIRDLL----------- 400 Query: 219 MPSRPFFCDDDHTAVPDSYPLLSELTEISEEDD 121 + FF +D V E++EEDD Sbjct: 401 --NHAFFAEDTGLRV-----------ELAEEDD 420
>WNK1_MOUSE (P83741) Serine/threonine-protein kinase WNK1 (EC 2.7.11.1)| (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1) Length = 2377 Score = 33.5 bits (75), Expect = 0.47 Identities = 28/110 (25%), Positives = 55/110 (50%) Frame = -2 Query: 579 SRALRGTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAANSSQSYYPS 400 ++++ GT ++APEM + DVY+FGM +LEMA + S+ + Sbjct: 380 AKSVIGTPEFMAPEMYEEKY---DESVDVYAFGMCMLEMA-------TSEYPYSECQNAA 429 Query: 399 WVYDKLTAPVVDAVCPVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVID 250 +Y ++T+ V A ++ E+ K I G CI+ +R ++ ++++ Sbjct: 430 QIYRRVTSGVKPASFDKVAIPEV--KEIIEG--CIRQNKDERYSIKDLLN 475
>UFO_HUMAN (P30530) Tyrosine-protein kinase receptor UFO precursor (EC| 2.7.10.1) (AXL oncogene) Length = 887 Score = 33.1 bits (74), Expect = 0.62 Identities = 29/108 (26%), Positives = 47/108 (43%), Gaps = 6/108 (5%) Frame = -2 Query: 510 SSKSDVYSFGMLLLEMAGGRRNADPNAANSSQSYYPSWVYDKLTAPVVDAVCPVASMHEL 331 +SKSDV+SFG+ + E+A + P NS +YD L + L Sbjct: 720 TSKSDVWSFGVTMWEIATRGQTPYPGVENSE-------IYDYL-----------RQGNRL 761 Query: 330 EKKL-CIVGLW-----CIQMKSHDRPTMSEVIDMLEGGFDGLQMPSRP 205 ++ C+ GL+ C ++ DRP+ +E+ + LE L P Sbjct: 762 KQPADCLDGLYALMSRCWELNPQDRPSFTELREDLENTLKALPPAQEP 809
>RMIL_AVII1 (P10533) Serine/threonine-protein kinase transforming protein Rmil| (EC 2.7.11.1) Length = 367 Score = 33.1 bits (74), Expect = 0.62 Identities = 31/114 (27%), Positives = 54/114 (47%), Gaps = 4/114 (3%) Frame = -2 Query: 570 LRGTIGYIAPEMIS-RSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAANSSQSYYPSWV 394 L G+I ++APE+I + S +SDVY+FG++L E+ G+ N N Q + V Sbjct: 223 LSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYS-NINNRDQIIF--MV 279 Query: 393 YDKLTAPVVDAV---CPVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVIDMLE 241 +P + V CP A + + C++ K +RP +++ +E Sbjct: 280 GRGYLSPDLSKVRSNCPKAMKRLMAE--------CLKKKRDERPLFPQILASIE 325
>RMIL_AVEVR (P27966) Serine/threonine-protein kinase transforming protein Rmil| (EC 2.7.11.1) Length = 450 Score = 33.1 bits (74), Expect = 0.62 Identities = 31/114 (27%), Positives = 54/114 (47%), Gaps = 4/114 (3%) Frame = -2 Query: 570 LRGTIGYIAPEMIS-RSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAANSSQSYYPSWV 394 L G+I ++APE+I + S +SDVY+FG++L E+ G+ N N Q + V Sbjct: 239 LSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYS-NINNRDQIIF--MV 295 Query: 393 YDKLTAPVVDAV---CPVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVIDMLE 241 +P + V CP A + + C++ K +RP +++ +E Sbjct: 296 GRGYLSPDLSKVRSNCPKAMKRLMAE--------CLKKKRDERPLFPQILASIE 341
>CPK15_ARATH (P92937) CBL-interacting serine/threonine-protein kinase 15 (EC| 2.7.11.1) (Serine/threonine-protein kinase ATPK10) (SOS2-like protein kinase PKS3) (SOS-interacting protein 2) (SNF1-related kinase 3.1) Length = 421 Score = 33.1 bits (74), Expect = 0.62 Identities = 17/37 (45%), Positives = 25/37 (67%) Frame = -2 Query: 564 GTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGG 454 GT Y+APE+ISR+ G K+DV+S G++L + G Sbjct: 173 GTPAYVAPEVISRN-GYDGFKADVWSCGVILFVLLAG 208
>BRAF1_COTJA (P34908) B-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (RMIL serine/threonine-protein kinase) (c-RMIL) Length = 807 Score = 33.1 bits (74), Expect = 0.62 Identities = 31/114 (27%), Positives = 54/114 (47%), Gaps = 4/114 (3%) Frame = -2 Query: 570 LRGTIGYIAPEMIS-RSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAANSSQSYYPSWV 394 L G+I ++APE+I + S +SDVY+FG++L E+ G+ N N Q + V Sbjct: 653 LSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYS-NINNRDQIIF--MV 709 Query: 393 YDKLTAPVVDAV---CPVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVIDMLE 241 +P + V CP A + + C++ K +RP +++ +E Sbjct: 710 GRGYLSPDLSKVRSNCPKAMKRLMAE--------CLKKKRDERPLFPQILASIE 755
>BLK_HUMAN (P51451) Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte| kinase) (p55-BLK) Length = 504 Score = 33.1 bits (74), Expect = 0.62 Identities = 19/45 (42%), Positives = 27/45 (60%) Frame = -2 Query: 558 IGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAAN 424 I + APE I FG + K+DV+SFG+LL+E+ R P +N Sbjct: 398 IKWTAPEAIH--FGVFTIKADVWSFGVLLMEVVTYGRVPYPGMSN 440
>LCK_HUMAN (P06239) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK) (T cell-specific protein-tyrosine kinase) Length = 508 Score = 33.1 bits (74), Expect = 0.62 Identities = 33/118 (27%), Positives = 52/118 (44%) Frame = -2 Query: 558 IGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAANSSQSYYPSWVYDKLT 379 I + APE I+ +G + KSDV+SFG+LL E+ R P N Y ++ Sbjct: 403 IKWTAPEAIN--YGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGY-RMV 459 Query: 378 APVVDAVCPVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVIDMLEGGFDGLQMPSRP 205 P CP +++L + C + + DRPT + +LE F + +P Sbjct: 460 RP---DNCP-EELYQLMR-------LCWKERPEDRPTFDYLRSVLEDFFTATEGQYQP 506
>NEK7_MOUSE (Q9ES74) Serine/threonine-protein kinase Nek7 (EC 2.7.11.1)| (NimA-related protein kinase 7) Length = 302 Score = 33.1 bits (74), Expect = 0.62 Identities = 33/118 (27%), Positives = 49/118 (41%), Gaps = 7/118 (5%) Frame = -2 Query: 579 SRALRGTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMA-------GGRRNADPNAANS 421 + +L GT Y++PE I + + KSD++S G LL EMA G + N Sbjct: 193 AHSLVGTPYYMSPERIHEN--GYNFKSDIWSLGCLLYEMAALQSPFYGDKMNLYSLCKKI 250 Query: 420 SQSYYPSWVYDKLTAPVVDAVCPVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVIDM 247 Q YP P+ S H E+ +V + CI RP ++ V D+ Sbjct: 251 EQCDYP----------------PLPSDHYSEELRQLVNI-CINPDPEKRPDIAYVYDV 291
>NEK7_HUMAN (Q8TDX7) Serine/threonine-protein kinase Nek7 (EC 2.7.11.1)| (NimA-related protein kinase 7) Length = 302 Score = 33.1 bits (74), Expect = 0.62 Identities = 33/118 (27%), Positives = 49/118 (41%), Gaps = 7/118 (5%) Frame = -2 Query: 579 SRALRGTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMA-------GGRRNADPNAANS 421 + +L GT Y++PE I + + KSD++S G LL EMA G + N Sbjct: 193 AHSLVGTPYYMSPERIHEN--GYNFKSDIWSLGCLLYEMAALQSPFYGDKMNLYSLCKKI 250 Query: 420 SQSYYPSWVYDKLTAPVVDAVCPVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVIDM 247 Q YP P+ S H E+ +V + CI RP ++ V D+ Sbjct: 251 EQCDYP----------------PLPSDHYSEELRQLVNM-CINPDPEKRPDVTYVYDV 291
>MKK2_YEAST (P32491) MAP kinase kinase MKK2/SSP33 (EC 2.7.12.2)| Length = 506 Score = 33.1 bits (74), Expect = 0.62 Identities = 19/38 (50%), Positives = 23/38 (60%) Frame = -2 Query: 564 GTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGR 451 GT Y+APE I S DV+S G+ LLE+AGGR Sbjct: 377 GTSFYMAPERIQGQ--PYSVTCDVWSLGLTLLEVAGGR 412
>BRAF1_CHICK (Q04982) B-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (Rmil serine/threonine-protein kinase) (c-Rmil) Length = 806 Score = 33.1 bits (74), Expect = 0.62 Identities = 31/114 (27%), Positives = 54/114 (47%), Gaps = 4/114 (3%) Frame = -2 Query: 570 LRGTIGYIAPEMIS-RSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAANSSQSYYPSWV 394 L G+I ++APE+I + S +SDVY+FG++L E+ G+ N N Q + V Sbjct: 653 LSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYS-NINNRDQIIF--MV 709 Query: 393 YDKLTAPVVDAV---CPVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVIDMLE 241 +P + V CP A + + C++ K +RP +++ +E Sbjct: 710 GRGYLSPDLSKVRSNCPKAMKRLMAE--------CLKKKRDERPLFPQILASIE 755
>BRAF1_MOUSE (P28028) B-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (Fragment) Length = 328 Score = 33.1 bits (74), Expect = 0.62 Identities = 31/114 (27%), Positives = 54/114 (47%), Gaps = 4/114 (3%) Frame = -2 Query: 570 LRGTIGYIAPEMIS-RSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAANSSQSYYPSWV 394 L G+I ++APE+I + S +SDVY+FG++L E+ G+ N N Q + V Sbjct: 175 LSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYS-NINNRDQIIF--MV 231 Query: 393 YDKLTAPVVDAV---CPVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVIDMLE 241 +P + V CP A + + C++ K +RP +++ +E Sbjct: 232 GRGYLSPDLSKVRSNCPKAMKRLMAE--------CLKKKRDERPLFPQILASIE 277
>BRAF1_HUMAN (P15056) B-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (p94) (v-Raf murine sarcoma viral oncogene homolog B1) Length = 766 Score = 33.1 bits (74), Expect = 0.62 Identities = 31/114 (27%), Positives = 54/114 (47%), Gaps = 4/114 (3%) Frame = -2 Query: 570 LRGTIGYIAPEMIS-RSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAANSSQSYYPSWV 394 L G+I ++APE+I + S +SDVY+FG++L E+ G+ N N Q + V Sbjct: 613 LSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYS-NINNRDQIIF--MV 669 Query: 393 YDKLTAPVVDAV---CPVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVIDMLE 241 +P + V CP A + + C++ K +RP +++ +E Sbjct: 670 GRGYLSPDLSKVRSNCPKAMKRLMAE--------CLKKKRDERPLFPQILASIE 715
>MLTK_HUMAN (Q9NYL2) Mitogen-activated protein kinase kinase kinase MLT (EC| 2.7.11.25) (MLK-like mitogen-activated protein triple kinase) (Leucine zipper-and sterile alpha motif-containing kinase) (Sterile alpha motif- and leucine zipper-containing kinase Length = 800 Score = 32.7 bits (73), Expect = 0.81 Identities = 30/123 (24%), Positives = 53/123 (43%), Gaps = 1/123 (0%) Frame = -2 Query: 573 ALRGTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAANSSQSYYPSW- 397 +L GT ++APE+I +S D YS+G++L EM R Q +W Sbjct: 165 SLVGTFPWMAPEVIQSL--PVSETCDTYSYGVVLWEML--TREVPFKGLEGLQ---VAWL 217 Query: 396 VYDKLTAPVVDAVCPVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVIDMLEGGFDGLQM 217 V +K + + CP + L + C + + RP+ ++I +LE + + Sbjct: 218 VVEKNERLTIPSSCPRSFAELLHQ--------CWEADAKKRPSFKQIISILESMSNDTSL 269 Query: 216 PSR 208 P + Sbjct: 270 PDK 272
>KS6A2_MOUSE (Q9WUT3) Ribosomal protein S6 kinase alpha-2 (EC 2.7.11.1)| (S6K-alpha 2) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3) (Protein-tyrosine kinase Mpk-9) (MAP kinase-activated protein kinase 1c) (M Length = 733 Score = 32.7 bits (73), Expect = 0.81 Identities = 16/37 (43%), Positives = 25/37 (67%) Frame = -2 Query: 564 GTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGG 454 GTI Y+APE+++R + +D +SFG+L+ EM G Sbjct: 221 GTIEYMAPEVVNRR--GHTQSADWWSFGVLMFEMLTG 255
>KS6A2_HUMAN (Q15349) Ribosomal protein S6 kinase alpha-2 (EC 2.7.11.1)| (S6K-alpha 2) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3) (MAP kinase-activated protein kinase 1c) (MAPKAPK1C) Length = 733 Score = 32.7 bits (73), Expect = 0.81 Identities = 16/37 (43%), Positives = 25/37 (67%) Frame = -2 Query: 564 GTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGG 454 GTI Y+APE+++R + +D +SFG+L+ EM G Sbjct: 221 GTIEYMAPEVVNRR--GHTQSADWWSFGVLMFEMLTG 255
>ITK_HUMAN (Q08881) Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2)| (T-cell-specific kinase) (Tyrosine-protein kinase Lyk) (Kinase EMT) Length = 620 Score = 32.7 bits (73), Expect = 0.81 Identities = 19/56 (33%), Positives = 31/56 (55%) Frame = -2 Query: 588 FVPSRALRGTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAANS 421 + S + + + +PE+ S F SSKSDV+SFG+L+ E+ + N +NS Sbjct: 512 YTSSTGTKFPVKWASPEVFS--FSRYSSKSDVWSFGVLMWEVFSEGKIPYENRSNS 565
>STE20_CANAL (Q92212) Serine/threonine-protein kinase STE20 homolog (EC 2.7.11.1)| Length = 1230 Score = 32.7 bits (73), Expect = 0.81 Identities = 27/104 (25%), Positives = 49/104 (47%) Frame = -2 Query: 564 GTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAANSSQSYYPSWVYDK 385 GT ++APE++SR K DV+S G++++EM G +P N + + Sbjct: 1110 GTPYWMAPEIVSRK--EYGPKVDVWSLGIMIIEMLEG----EPPYLNETPLRALYLIATN 1163 Query: 384 LTAPVVDAVCPVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVI 253 T + D P + +++ K L WC+Q+ + R E++ Sbjct: 1164 GTPKLKD---PESLSYDIRKFLA----WCLQVDFNKRADADELL 1200
>KPC2_DROME (P13677) Protein kinase C, eye isozyme (EC 2.7.11.13) (PKC)| (dPKC53E(EY)) (Protein INAC) (Inactivation no after-potential C protein) (Photoreceptor-specific PKC) (Eye-PKC) Length = 700 Score = 32.7 bits (73), Expect = 0.81 Identities = 17/43 (39%), Positives = 26/43 (60%) Frame = -2 Query: 579 SRALRGTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGR 451 +R GT Y+APE++ S+ S +D +SFG+LL E G+ Sbjct: 527 TRTFCGTPNYMAPEIV--SYDPYSIAADWWSFGVLLFEFMAGQ 567
>YSK4_HUMAN (Q56UN5) SPS1/STE20-related protein kinase YSK4 (EC 2.7.11.1)| (Regulated in COPD, protein kinase) Length = 1328 Score = 32.7 bits (73), Expect = 0.81 Identities = 16/42 (38%), Positives = 27/42 (64%) Frame = -2 Query: 576 RALRGTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGR 451 +++ GT ++APE+I+ S KSD++S G + EMA G+ Sbjct: 1225 KSMHGTPYWMAPEVINES--GYGRKSDIWSIGCTVFEMATGK 1264
>SRC_CHICK (P00523) Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2)| (p60-Src) (c-Src) (pp60c-src) Length = 532 Score = 32.7 bits (73), Expect = 0.81 Identities = 32/118 (27%), Positives = 47/118 (39%) Frame = -2 Query: 558 IGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAANSSQSYYPSWVYDKLT 379 I + APE + +G + KSDV+SFG+LL E+ R P N V D++ Sbjct: 425 IKWTAPE--AALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNRE-------VLDQVE 475 Query: 378 APVVDAVCPVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVIDMLEGGFDGLQMPSRP 205 CP L +C C + +RPT + LE F + +P Sbjct: 476 RG-YRMPCPPECPESLHDLMC----QCWRKDPEERPTFEYLQAFLEDYFTSTEPQYQP 528
>PKN2_CLOAB (Q97IC2) Probable serine/threonine protein kinase CAC1728 (EC| 2.7.11.1) Length = 657 Score = 32.7 bits (73), Expect = 0.81 Identities = 31/112 (27%), Positives = 52/112 (46%), Gaps = 5/112 (4%) Frame = -2 Query: 564 GTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAANSSQSYYPSWVYDK 385 G+ Y++PE + ++D+YSFG++L EMA G+ P A++ S + D Sbjct: 171 GSAHYLSPEQAQGI--PVDCRTDIYSFGIVLYEMATGK---VPYDADTPVSIALKHIQDA 225 Query: 384 LTAPVVDAVCPVASMHELEKKLCI----VGLWCIQMKSHDR-PTMSEVIDML 244 P +EL K + I + L CI+ K +R +E++D L Sbjct: 226 AVPP-----------NELNKDIPIALNKMILRCIEKKPENRYQNANEILDEL 266
>PKNA2_BIFLO (Q8G4G1) Probable serine/threonine-protein kinase pknA2 (EC| 2.7.11.1) Length = 757 Score = 32.7 bits (73), Expect = 0.81 Identities = 16/40 (40%), Positives = 25/40 (62%) Frame = -2 Query: 570 LRGTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGR 451 L GT Y+APEMI + +++ D+YS G++ EM G+ Sbjct: 176 LLGTAAYLAPEMIENN--QATAQGDLYSVGIMAWEMLTGK 213
>NEK6_HUMAN (Q9HC98) Serine/threonine-protein kinase Nek6 (EC 2.7.11.1)| (NimA-related protein kinase 6) (Protein kinase SID6-1512) Length = 313 Score = 32.7 bits (73), Expect = 0.81 Identities = 33/115 (28%), Positives = 46/115 (40%), Gaps = 7/115 (6%) Frame = -2 Query: 579 SRALRGTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMA-------GGRRNADPNAANS 421 + +L GT Y++PE I + + KSD++S G LL EMA G + N Sbjct: 204 AHSLVGTPYYMSPERIHEN--GYNFKSDIWSLGCLLYEMAALQSPFYGDKMNLFSLCQKI 261 Query: 420 SQSYYPSWVYDKLTAPVVDAVCPVASMHELEKKLCIVGLWCIQMKSHDRPTMSEV 256 Q YP P+ H EK +V + CI H RP + V Sbjct: 262 EQCDYP----------------PLPGEHYSEKLRELVSM-CICPDPHQRPDIGYV 299
>FES_FSVST (P00543) Tyrosine-protein kinase transforming protein Fes (EC| 2.7.10.2) Length = 477 Score = 32.7 bits (73), Expect = 0.81 Identities = 18/45 (40%), Positives = 28/45 (62%) Frame = -2 Query: 558 IGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAAN 424 + + APE ++ +G SS+SDV+SFG+LL E + PN +N Sbjct: 379 VKWTAPEALN--YGRYSSESDVWSFGILLWETFSLGASPYPNLSN 421
>KS6AA_XENLA (P10665) Ribosomal protein S6 kinase 2 alpha (EC 2.7.11.1)| (Ribosomal protein S6 kinase II alpha) (S6KII-alpha) (P90-RSK) (MAP kinase-activated protein kinase 1) (MAPK-activated protein kinase 1) (MAPKAP kinase 1) (MAPKAPK-1) Length = 733 Score = 32.3 bits (72), Expect = 1.1 Identities = 15/37 (40%), Positives = 25/37 (67%) Frame = -2 Query: 564 GTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGG 454 GT+ Y+APE+++R S +D +S+G+L+ EM G Sbjct: 224 GTVEYMAPEVVNRQ--GHSHSADWWSYGVLMFEMLTG 258
>KPCG_BOVIN (P05128) Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma)| (Fragment) Length = 682 Score = 32.3 bits (72), Expect = 1.1 Identities = 18/43 (41%), Positives = 25/43 (58%) Frame = -2 Query: 579 SRALRGTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGR 451 +R GT YIAPE+I ++ D +SFG+LL EM G+ Sbjct: 497 TRTFCGTPDYIAPEII--AYQPYGKSVDWWSFGVLLYEMLAGQ 537
>KAND_SCHPO (Q10078) Putative serine/threonine-protein kinase C3H1.13 (EC| 2.7.11.1) Length = 344 Score = 32.3 bits (72), Expect = 1.1 Identities = 27/108 (25%), Positives = 47/108 (43%), Gaps = 1/108 (0%) Frame = -2 Query: 561 TIGYIAPEMISRSFGA-ISSKSDVYSFGMLLLEMAGGRRNADPNAANSSQSYYPSWVYDK 385 T+ + APE+ G+ I+ K+D++SFG L + +A P SQ Sbjct: 242 TMPFRAPELFHVKAGSTITEKADIWSFGCTLYTIMF---HASPFEREVSQG-------GS 291 Query: 384 LTAPVVDAVCPVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVIDMLE 241 L V +A H LC + C+Q + + RP+ E++ ++ Sbjct: 292 LALAVCNAQYSFPRKHPYSTLLCEIVEACLQREPNKRPSARELLSKID 339
>KS6A6_HUMAN (Q9UK32) Ribosomal protein S6 kinase alpha-6 (EC 2.7.11.1)| (S6K-alpha 6) (90 kDa ribosomal protein S6 kinase 6) (p90-RSK 6) (Ribosomal S6 kinase 4) (RSK-4) (pp90RSK4) Length = 745 Score = 32.3 bits (72), Expect = 1.1 Identities = 15/37 (40%), Positives = 25/37 (67%) Frame = -2 Query: 564 GTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGG 454 GT+ Y+APE+++R S +D +S+G+L+ EM G Sbjct: 235 GTVEYMAPEVVNRR--GHSQSADWWSYGVLMFEMLTG 269
>KS6A3_MOUSE (P18654) Ribosomal protein S6 kinase alpha-3 (EC 2.7.11.1)| (S6K-alpha 3) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2) (MAP kinase-activated protein kinase 1b) (MAPKAPK1B) Length = 740 Score = 32.3 bits (72), Expect = 1.1 Identities = 15/37 (40%), Positives = 25/37 (67%) Frame = -2 Query: 564 GTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGG 454 GT+ Y+APE+++R + +D +SFG+L+ EM G Sbjct: 230 GTVEYMAPEVVNRR--GHTQSADWWSFGVLMFEMLTG 264
>KS6A3_HUMAN (P51812) Ribosomal protein S6 kinase alpha-3 (EC 2.7.11.1)| (S6K-alpha 3) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2) (Insulin-stimulated protein kinase 1) (ISPK-1) (MAP kinase-activated protei Length = 740 Score = 32.3 bits (72), Expect = 1.1 Identities = 15/37 (40%), Positives = 25/37 (67%) Frame = -2 Query: 564 GTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGG 454 GT+ Y+APE+++R + +D +SFG+L+ EM G Sbjct: 230 GTVEYMAPEVVNRR--GHTQSADWWSFGVLMFEMLTG 264
>WNK4_RAT (Q7TPK6) Serine/threonine-protein kinase WNK4 (EC 2.7.11.1)| (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4) Length = 1222 Score = 32.3 bits (72), Expect = 1.1 Identities = 16/40 (40%), Positives = 25/40 (62%) Frame = -2 Query: 579 SRALRGTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMA 460 ++++ GT ++APEM + DVY+FGM +LEMA Sbjct: 330 AKSVIGTPEFMAPEMYEEKY---DEAVDVYAFGMCMLEMA 366
>WNK4_MOUSE (Q80UE6) Serine/threonine-protein kinase WNK4 (EC 2.7.11.1)| (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4) Length = 1222 Score = 32.3 bits (72), Expect = 1.1 Identities = 16/40 (40%), Positives = 25/40 (62%) Frame = -2 Query: 579 SRALRGTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMA 460 ++++ GT ++APEM + DVY+FGM +LEMA Sbjct: 330 AKSVIGTPEFMAPEMYEEKY---DEAVDVYAFGMCMLEMA 366
>LIMK1_CHICK (Q8QFP8) LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1) (chLIMK1)| Length = 662 Score = 32.3 bits (72), Expect = 1.1 Identities = 23/55 (41%), Positives = 35/55 (63%), Gaps = 5/55 (9%) Frame = -2 Query: 582 PSRALRGTIG----YIAPEMIS-RSFGAISSKSDVYSFGMLLLEMAGGRRNADPN 433 P R R T+ ++APEMI+ RS+ K D++SFG++L E+ GR +ADP+ Sbjct: 508 PDRKKRYTVVGNPYWMAPEMINGRSY---DEKVDIFSFGIVLCEII-GRVSADPD 558
>WNK4_HUMAN (Q96J92) Serine/threonine-protein kinase WNK4 (EC 2.7.11.1)| (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4) Length = 1243 Score = 32.3 bits (72), Expect = 1.1 Identities = 16/40 (40%), Positives = 25/40 (62%) Frame = -2 Query: 579 SRALRGTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMA 460 ++++ GT ++APEM + DVY+FGM +LEMA Sbjct: 333 AKSVIGTPEFMAPEMYEEKY---DEAVDVYAFGMCMLEMA 369
>KPCG_RAT (P63319) Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma)| Length = 697 Score = 32.3 bits (72), Expect = 1.1 Identities = 18/43 (41%), Positives = 25/43 (58%) Frame = -2 Query: 579 SRALRGTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGR 451 +R GT YIAPE+I ++ D +SFG+LL EM G+ Sbjct: 512 TRTFCGTPDYIAPEII--AYQPYGKSVDWWSFGVLLYEMLAGQ 552
>KPCG_RABIT (P10829) Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma)| (PKC-delta) Length = 697 Score = 32.3 bits (72), Expect = 1.1 Identities = 18/43 (41%), Positives = 25/43 (58%) Frame = -2 Query: 579 SRALRGTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGR 451 +R GT YIAPE+I ++ D +SFG+LL EM G+ Sbjct: 512 TRTFCGTPDYIAPEII--AYQPYGKSVDWWSFGVLLYEMLAGQ 552
>KPCG_MOUSE (P63318) Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma)| Length = 697 Score = 32.3 bits (72), Expect = 1.1 Identities = 18/43 (41%), Positives = 25/43 (58%) Frame = -2 Query: 579 SRALRGTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGR 451 +R GT YIAPE+I ++ D +SFG+LL EM G+ Sbjct: 512 TRTFCGTPDYIAPEII--AYQPYGKSVDWWSFGVLLYEMLAGQ 552
>KPCG_HUMAN (P05129) Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma)| Length = 697 Score = 32.3 bits (72), Expect = 1.1 Identities = 18/43 (41%), Positives = 25/43 (58%) Frame = -2 Query: 579 SRALRGTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGR 451 +R GT YIAPE+I ++ D +SFG+LL EM G+ Sbjct: 512 TRTFCGTPDYIAPEII--AYQPYGKSVDWWSFGVLLYEMLAGQ 552
>MLTK_MOUSE (Q9ESL4) Mitogen-activated protein kinase kinase kinase MLT (EC| 2.7.11.25) (MLK-like mitogen-activated protein triple kinase) (Leucine zipper-and sterile alpha motif kinase ZAK) (Sterile alpha motif- and leucine zipper-containing kinase AZK) ( Length = 802 Score = 32.3 bits (72), Expect = 1.1 Identities = 30/123 (24%), Positives = 53/123 (43%), Gaps = 1/123 (0%) Frame = -2 Query: 573 ALRGTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAANSSQSYYPSW- 397 +L GT ++APE+I +S D YS+G++L EM R Q +W Sbjct: 165 SLVGTFPWMAPEVIQSL--PVSETCDTYSYGVVLWEML--TREVPFKGLEGLQ---VAWL 217 Query: 396 VYDKLTAPVVDAVCPVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVIDMLEGGFDGLQM 217 V +K + + CP + L + C + + RP+ ++I +LE + + Sbjct: 218 VVEKNERLTIPSSCPRSFAELLHQ--------CWEADAKKRPSFKQIISILESMSNDTNL 269 Query: 216 PSR 208 P + Sbjct: 270 PDQ 272
>LCK_CHICK (P42683) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (Protein-tyrosine kinase C-TKL) (p56tk1) Length = 507 Score = 32.3 bits (72), Expect = 1.1 Identities = 19/45 (42%), Positives = 26/45 (57%) Frame = -2 Query: 558 IGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAAN 424 I + APE I+ +G + KSDV+SFG+LL E+ R P N Sbjct: 402 IKWTAPEAIN--YGTFTIKSDVWSFGILLTEIVTYGRIPYPGMTN 444
>KS6A1_HUMAN (Q15418) Ribosomal protein S6 kinase alpha-1 (EC 2.7.11.1)| (S6K-alpha 1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (Ribosomal S6 kinase 1) (RSK-1) (pp90RSK1) (MAP kinase-activated protein kinase 1a) (MAPKAPK1A) Length = 735 Score = 32.3 bits (72), Expect = 1.1 Identities = 15/37 (40%), Positives = 25/37 (67%) Frame = -2 Query: 564 GTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGG 454 GT+ Y+APE+++R S +D +S+G+L+ EM G Sbjct: 224 GTVEYMAPEVVNRQ--GHSHSADWWSYGVLMFEMLTG 258
>KS6AA_CHICK (P18652) Ribosomal protein S6 kinase 2 alpha (EC 2.7.11.1)| (Ribosomal protein S6 kinase II alpha) (S6KII-alpha) (P90-RSK) (MAP kinase-activated protein kinase 1) (MAPK-activated protein kinase 1) (MAPKAP kinase 1) (MAPKAPK-1) Length = 752 Score = 32.3 bits (72), Expect = 1.1 Identities = 15/37 (40%), Positives = 25/37 (67%) Frame = -2 Query: 564 GTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGG 454 GT+ Y+APE+++R S +D +S+G+L+ EM G Sbjct: 242 GTVEYMAPEVVNRQ--GHSHSADWWSYGVLMFEMLTG 276
>FES_MOUSE (P16879) Proto-oncogene tyrosine-protein kinase Fes/Fps (EC| 2.7.10.2) (C-Fes) Length = 820 Score = 32.3 bits (72), Expect = 1.1 Identities = 18/45 (40%), Positives = 27/45 (60%) Frame = -2 Query: 558 IGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAAN 424 + + APE ++ +G SS+SDV+SFG+LL E + PN N Sbjct: 722 VKWTAPEALN--YGRYSSESDVWSFGILLWETFSLGASPYPNLTN 764
>EPB1A_XENLA (Q91571) Ephrin type-B receptor 1-A precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor XEK) Length = 985 Score = 32.3 bits (72), Expect = 1.1 Identities = 28/95 (29%), Positives = 49/95 (51%), Gaps = 1/95 (1%) Frame = -2 Query: 525 SFGAISSKSDVYSFGMLLLE-MAGGRRNADPNAANSSQSYYPSWVYDKLTAPVVDAVCPV 349 ++ +S SDV+S+G+++ E M+ G R P S+Q + D P +D CP Sbjct: 798 AYRKFTSASDVWSYGIVMWEVMSYGER---PYWTMSNQDVINAIEQDYRLPPPMD--CP- 851 Query: 348 ASMHELEKKLCIVGLWCIQMKSHDRPTMSEVIDML 244 A++H+L L C Q + RP ++E+++ L Sbjct: 852 AALHQLM-------LDCWQKDRNSRPRLAEIVNTL 879
>ABL1_CAEEL (P03949) Tyrosine-protein kinase abl-1 (EC 2.7.10.2)| Length = 1224 Score = 32.0 bits (71), Expect = 1.4 Identities = 17/33 (51%), Positives = 24/33 (72%) Frame = -2 Query: 558 IGYIAPEMISRSFGAISSKSDVYSFGMLLLEMA 460 I + APE ++ F SSKSDV++FG+LL E+A Sbjct: 472 IKWTAPEGLA--FNTFSSKSDVWAFGVLLWEIA 502
>PKN6_MYXXA (P54738) Serine/threonine-protein kinase pkn6 (EC 2.7.11.1)| Length = 710 Score = 32.0 bits (71), Expect = 1.4 Identities = 23/86 (26%), Positives = 42/86 (48%), Gaps = 2/86 (2%) Frame = -2 Query: 570 LRGTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRR--NADPNAANSSQSYYPSW 397 ++G + Y+ PE + A+ + DVY+ G++L E+ G+R +A + + + S+ Sbjct: 179 VKGKVAYMPPEQLQAK--AMDRRVDVYALGVVLYELLTGKRPFDATTDVSVMQAILFESF 236 Query: 396 VYDKLTAPVVDAVCPVASMHELEKKL 319 + P V PVA L+K L Sbjct: 237 IPVSARRPDV----PVALQQVLDKAL 258
>PKN2_CORGL (Q8NU97) Serine/threonine protein kinases pknA (EC 2.7.11.1)| Length = 469 Score = 32.0 bits (71), Expect = 1.4 Identities = 19/51 (37%), Positives = 28/51 (54%) Frame = -2 Query: 564 GTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAANSSQS 412 GT Y++PE +++ SD+YS G++ EM GRR P +SS S Sbjct: 186 GTAQYVSPEQAQGK--EVTAASDIYSLGVVGYEMMAGRR---PFTGDSSVS 231
>EPHA8_RAT (P29321) Ephrin type-A receptor 8 (EC 2.7.10.1) (Tyrosine-protein| kinase receptor EEK) (EPH- and ELK-related kinase) (Fragment) Length = 372 Score = 32.0 bits (71), Expect = 1.4 Identities = 36/111 (32%), Positives = 53/111 (47%), Gaps = 5/111 (4%) Frame = -2 Query: 558 IGYIAPEMISRSFGAISSKSDVYSFGMLLLE-MAGGRR----NADPNAANSSQSYYPSWV 394 I + APE I+ F SS SDV+SFG+++ E +A G R + + +S + Y Sbjct: 169 IRWTAPEAIA--FRTFSSASDVWSFGVVMWEVLAYGERPYWNMTNQDVISSVEEGY---- 222 Query: 393 YDKLTAPVVDAVCPVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVIDMLE 241 +L AP+ CP A +H+L L C RP S V+ +LE Sbjct: 223 --RLPAPM---GCPRA-LHQLM-------LDCWHKDRAQRPRFSHVVSVLE 260
>HTK16_HYDAT (P53356) Tyrosine-protein kinase HTK16 (EC 2.7.10.2)| Length = 757 Score = 32.0 bits (71), Expect = 1.4 Identities = 16/35 (45%), Positives = 24/35 (68%) Frame = -2 Query: 567 RGTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEM 463 R + + APE I+ +G S+KSDV+S+G+ L EM Sbjct: 647 RWPVRWYAPESIN--YGTFSTKSDVWSYGITLWEM 679
>BMR1A_HUMAN (P36894) Bone morphogenetic protein receptor type IA precursor (EC| 2.7.11.30) (Serine/threonine-protein kinase receptor R5) (SKR5) (Activin receptor-like kinase 3) (ALK-3) (CD292 antigen) Length = 532 Score = 32.0 bits (71), Expect = 1.4 Identities = 17/46 (36%), Positives = 26/46 (56%), Gaps = 4/46 (8%) Frame = -2 Query: 585 VPSRALRGTIGYIAPEMISRSFGAISSK----SDVYSFGMLLLEMA 460 VP GT Y+APE++ S + +D+YSFG+++ EMA Sbjct: 396 VPLNTRVGTKRYMAPEVLDESLNKNHFQPYIMADIYSFGLIIWEMA 441
>EPHA6_RAT (P54758) Ephrin type-A receptor 6 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2) Length = 1035 Score = 32.0 bits (71), Expect = 1.4 Identities = 42/142 (29%), Positives = 68/142 (47%), Gaps = 8/142 (5%) Frame = -2 Query: 558 IGYIAPEMISRSFGAISSKSDVYSFGMLLLE-MAGGRRNADPNAANSSQSYYPSWVYD-K 385 I + APE I+ + SS SDV+S+G+++ E M+ G R P S+Q S + Sbjct: 839 IRWTAPEAIA--YRKFSSASDVWSYGIVMWEVMSYGER---PYWEMSNQDVILSIEEGYR 893 Query: 384 LTAPVVDAVCPVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVIDMLEGGFDGLQMPSRP 205 L AP+ CP S+H+L L C Q + + RP ++++ L+ ++ PS Sbjct: 894 LPAPM---GCP-PSLHQLM-------LHCWQKERNHRPKFTDIVSFLD---KLIRNPSAL 939 Query: 204 FFCDDDHTAVPDS------YPL 157 +D +P+S YPL Sbjct: 940 HTLVEDILVMPESPGDVPEYPL 961
>UFO_MOUSE (Q00993) Tyrosine-protein kinase receptor UFO precursor (EC| 2.7.10.1) (Adhesion-related kinase) Length = 888 Score = 31.6 bits (70), Expect = 1.8 Identities = 29/110 (26%), Positives = 46/110 (41%), Gaps = 8/110 (7%) Frame = -2 Query: 510 SSKSDVYSFGMLLLEMAGGRRNADPNAANSSQSYYPSWVYD------KLTAPV--VDAVC 355 +SKSDV+SFG+ + E+A + P NS +YD +L PV +D + Sbjct: 721 TSKSDVWSFGVTMWEIATRGQTPYPGVENSE-------IYDYLRQGNRLKQPVDFLDGLY 773 Query: 354 PVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVIDMLEGGFDGLQMPSRP 205 + S C ++ DRP+ +E+ + LE L P Sbjct: 774 SLMSR-------------CWELNPRDRPSFAELREDLENTLKALPPAQEP 810
>SRC_AVISS (P14084) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 567 Score = 31.6 bits (70), Expect = 1.8 Identities = 31/109 (28%), Positives = 44/109 (40%) Frame = -2 Query: 558 IGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAANSSQSYYPSWVYDKLT 379 I + APE + +G + KSDV+SFG+LL E+ R P N V D++ Sbjct: 425 IKWTAPE--AALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNRE-------VLDQVE 475 Query: 378 APVVDAVCPVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVIDMLEGGF 232 CP L +C C + +RPT + LE F Sbjct: 476 RG-YRMPCPPECPESLHDLMC----QCWRKDPEERPTFEYLQAFLEDYF 519
>YES_MOUSE (Q04736) Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2)| (p61-Yes) (c-Yes) Length = 540 Score = 31.6 bits (70), Expect = 1.8 Identities = 33/118 (27%), Positives = 48/118 (40%) Frame = -2 Query: 558 IGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAANSSQSYYPSWVYDKLT 379 I + APE + +G + KSDV+SFG+L E+ R P N Y ++ Sbjct: 433 IKWTAPE--AALYGRFTIKSDVWSFGILQTELVTKGRVPYPGMVNREVLEQVERGY-RMP 489 Query: 378 APVVDAVCPVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVIDMLEGGFDGLQMPSRP 205 P CP S+HEL C + +RPT + LE F + +P Sbjct: 490 CP---QGCP-ESLHELMN-------LCWKKDPDERPTFEYIQSFLEDYFTATEPQYQP 536
>SKH1_SCHPO (Q9Y884) MAP kinase kinase skh1/pek1 (EC 2.7.12.2)| Length = 363 Score = 31.6 bits (70), Expect = 1.8 Identities = 17/38 (44%), Positives = 25/38 (65%) Frame = -2 Query: 564 GTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGR 451 GT Y+APE IS G+ + SD++S G+ L+E+A R Sbjct: 241 GTSYYMAPERISG--GSYTISSDIWSLGLTLMEVALNR 276
>MP2K1_CRIGR (Q63980) Dual specificity mitogen-activated protein kinase kinase 1| (EC 2.7.12.2) (MAP kinase kinase 1) (MAPKK 1) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK1) Length = 393 Score = 31.6 bits (70), Expect = 1.8 Identities = 16/43 (37%), Positives = 27/43 (62%) Frame = -2 Query: 564 GTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADP 436 GT Y++PE + + ++ +SD++S G+ L+EMA GR P Sbjct: 225 GTRSYMSPERLQGTHYSV--QSDIWSMGLSLVEMAVGRYPIPP 265
>SRK3_SPOLA (P42689) Tyrosine-protein kinase SRK3 (EC 2.7.10.2) (Fragment)| Length = 334 Score = 31.6 bits (70), Expect = 1.8 Identities = 32/121 (26%), Positives = 49/121 (40%), Gaps = 7/121 (5%) Frame = -2 Query: 582 PSRALRGTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAANSSQSYYP 403 P + I + APE + + + KSDV+SFG+L+ E+ R P N Sbjct: 218 PREGTKFPIKWTAPE--AALYNRFTIKSDVWSFGVLISEIVTHGRMPYPGMTNRQ----- 270 Query: 402 SWVYDKLTAPVVDAV-------CPVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVIDML 244 V++AV CP L K + L C + + DRPT + ++L Sbjct: 271 ----------VLEAVDRGYRMPCPEGCPDPLYK----IMLSCWKHEPDDRPTFESLKNLL 316 Query: 243 E 241 E Sbjct: 317 E 317
>SRC2_XENLA (P13116) Tyrosine-protein kinase Src-2 (EC 2.7.10.2) (p60-Src-2)| Length = 531 Score = 31.6 bits (70), Expect = 1.8 Identities = 33/118 (27%), Positives = 47/118 (39%) Frame = -2 Query: 558 IGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAANSSQSYYPSWVYDKLT 379 I + APE + +G + KSDV+SFG+LL E+ R P N Y Sbjct: 424 IKWTAPE--AALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPC 481 Query: 378 APVVDAVCPVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVIDMLEGGFDGLQMPSRP 205 P CP S+H+L C + +RPT + LE F + +P Sbjct: 482 PP----DCP-ESLHDLM-------FQCWRKDPEERPTFEYLQAFLEDYFTATEPQYQP 527
>SRC1_XENLA (P13115) Tyrosine-protein kinase Src-1 (EC 2.7.10.2) (p60-Src-1)| Length = 531 Score = 31.6 bits (70), Expect = 1.8 Identities = 33/118 (27%), Positives = 47/118 (39%) Frame = -2 Query: 558 IGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAANSSQSYYPSWVYDKLT 379 I + APE + +G + KSDV+SFG+LL E+ R P N Y Sbjct: 424 IKWTAPE--AALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPC 481 Query: 378 APVVDAVCPVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVIDMLEGGFDGLQMPSRP 205 P CP S+H+L C + +RPT + LE F + +P Sbjct: 482 PP----DCP-ESLHDLM-------FQCWRKDPEERPTFEYLQAFLEDYFTATEPQYQP 527
>PKNL_MYCTU (O53510) Probable serine/threonine-protein kinase pknL (EC| 2.7.11.1) Length = 399 Score = 31.6 bits (70), Expect = 1.8 Identities = 16/46 (34%), Positives = 25/46 (54%) Frame = -2 Query: 591 SFVPSRALRGTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGG 454 S + + GT Y++PE + G +SDVYS G+L+ E+ G Sbjct: 171 SITSTGVILGTAAYLSPEQVRD--GNADPRSDVYSVGVLVYELLTG 214
>PKNL_MYCBO (Q7TYY6) Probable serine/threonine-protein kinase pknL (EC| 2.7.11.1) Length = 399 Score = 31.6 bits (70), Expect = 1.8 Identities = 16/46 (34%), Positives = 25/46 (54%) Frame = -2 Query: 591 SFVPSRALRGTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGG 454 S + + GT Y++PE + G +SDVYS G+L+ E+ G Sbjct: 171 SITSTGVILGTAAYLSPEQVRD--GNADPRSDVYSVGVLVYELLTG 214
>KS6AB_XENLA (P10666) Ribosomal protein S6 kinase 2 beta (EC 2.7.11.1)| (Ribosomal protein S6 kinase II beta) (S6KII-beta) (P90-RSK) Length = 629 Score = 31.6 bits (70), Expect = 1.8 Identities = 15/37 (40%), Positives = 25/37 (67%) Frame = -2 Query: 564 GTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGG 454 GT+ Y+APE+++R S +D +S+G+L+ EM G Sbjct: 224 GTVEYMAPEVVNRQ--GHSHGADWWSYGVLMFEMLTG 258
>MP2K1_RAT (Q01986) Dual specificity mitogen-activated protein kinase kinase 1| (EC 2.7.12.2) (MAP kinase kinase 1) (MAPKK 1) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK1) Length = 392 Score = 31.6 bits (70), Expect = 1.8 Identities = 16/43 (37%), Positives = 27/43 (62%) Frame = -2 Query: 564 GTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADP 436 GT Y++PE + + ++ +SD++S G+ L+EMA GR P Sbjct: 224 GTRSYMSPERLQGTHYSV--QSDIWSMGLSLVEMAVGRYPIPP 264
>MP2K1_RABIT (P29678) Dual specificity mitogen-activated protein kinase kinase 1| (EC 2.7.12.2) (MAP kinase kinase 1) (MAPKK 1) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK1) Length = 392 Score = 31.6 bits (70), Expect = 1.8 Identities = 16/43 (37%), Positives = 27/43 (62%) Frame = -2 Query: 564 GTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADP 436 GT Y++PE + + ++ +SD++S G+ L+EMA GR P Sbjct: 224 GTRSYMSPERLQGTHYSV--QSDIWSMGLSLVEMAVGRYPIPP 264
>MP2K1_MOUSE (P31938) Dual specificity mitogen-activated protein kinase kinase 1| (EC 2.7.12.2) (MAP kinase kinase 1) (MAPKK 1) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK1) Length = 392 Score = 31.6 bits (70), Expect = 1.8 Identities = 16/43 (37%), Positives = 27/43 (62%) Frame = -2 Query: 564 GTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADP 436 GT Y++PE + + ++ +SD++S G+ L+EMA GR P Sbjct: 224 GTRSYMSPERLQGTHYSV--QSDIWSMGLSLVEMAVGRYPIPP 264
>MP2K1_HUMAN (Q02750) Dual specificity mitogen-activated protein kinase kinase 1| (EC 2.7.12.2) (MAP kinase kinase 1) (MAPKK 1) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK1) Length = 392 Score = 31.6 bits (70), Expect = 1.8 Identities = 16/43 (37%), Positives = 27/43 (62%) Frame = -2 Query: 564 GTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADP 436 GT Y++PE + + ++ +SD++S G+ L+EMA GR P Sbjct: 224 GTRSYMSPERLQGTHYSV--QSDIWSMGLSLVEMAVGRYPIPP 264
>KS6A_CAEEL (Q21734) Putative ribosomal protein S6 kinase alpha (EC 2.7.11.1)| Length = 784 Score = 31.6 bits (70), Expect = 1.8 Identities = 16/37 (43%), Positives = 24/37 (64%) Frame = -2 Query: 564 GTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGG 454 GT+ Y+APE+I+R S +D +S G+L+ EM G Sbjct: 266 GTVEYMAPEVINRR--GHSMAADFWSLGVLMFEMLTG 300
>YES_HUMAN (P07947) Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2)| (p61-Yes) (c-Yes) Length = 542 Score = 31.6 bits (70), Expect = 1.8 Identities = 33/118 (27%), Positives = 48/118 (40%) Frame = -2 Query: 558 IGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAANSSQSYYPSWVYDKLT 379 I + APE + +G + KSDV+SFG+L E+ R P N Y ++ Sbjct: 435 IKWTAPE--AALYGRFTIKSDVWSFGILQTELVTKGRVPYPGMVNREVLEQVERGY-RMP 491 Query: 378 APVVDAVCPVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVIDMLEGGFDGLQMPSRP 205 P CP S+HEL C + +RPT + LE F + +P Sbjct: 492 CP---QGCP-ESLHELMN-------LCWKKDPDERPTFEYIQSFLEDYFTATEPQYQP 538
>RAF1_XENLA (P09560) RAF proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (C-RAF) Length = 638 Score = 31.6 bits (70), Expect = 1.8 Identities = 17/40 (42%), Positives = 27/40 (67%), Gaps = 1/40 (2%) Frame = -2 Query: 570 LRGTIGYIAPEMIS-RSFGAISSKSDVYSFGMLLLEMAGG 454 L G+I ++APE+I + S +SDVYS+G++L E+ G Sbjct: 496 LTGSILWMAPEVIRMQDNNPFSFQSDVYSYGIVLYELMTG 535
>INSR_AEDAE (Q93105) Insulin-like receptor precursor (EC 2.7.10.1) (MIR)| [Contains: Insulin-like receptor alpha chain; Insulin-like receptor beta chain] Length = 1390 Score = 31.6 bits (70), Expect = 1.8 Identities = 33/120 (27%), Positives = 52/120 (43%), Gaps = 12/120 (10%) Frame = -2 Query: 567 RGTIGYI-----APEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAANSSQSYYP 403 +GT G++ APE + G SS SDV+S+G++L EM A + Y Sbjct: 1195 KGTKGFLPVRWMAPESLKD--GIFSSSSDVFSYGVVLWEM-----------ATLASQPYQ 1241 Query: 402 SWVYDKLTAPVVDA-------VCPVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVIDML 244 D++ V+D CP +++ L ++ C Q + RPT E+I L Sbjct: 1242 GLTNDQVLRYVIDGGVMERPENCP-DNLYNLMRR-------CWQHRPTARPTFMEIISEL 1293
>BMR1A_MOUSE (P36895) Bone morphogenetic protein receptor type IA precursor (EC| 2.7.11.30) (Serine/threonine-protein kinase receptor R5) (SKR5) (Activin receptor-like kinase 3) (ALK-3) (BMP-2/BMP-4 receptor) Length = 532 Score = 31.6 bits (70), Expect = 1.8 Identities = 16/46 (34%), Positives = 26/46 (56%), Gaps = 4/46 (8%) Frame = -2 Query: 585 VPSRALRGTIGYIAPEMISRSFGAISSK----SDVYSFGMLLLEMA 460 +P GT Y+APE++ S + +D+YSFG+++ EMA Sbjct: 396 IPLNTRVGTKRYMAPEVLDESLNKNHFQPYIMADIYSFGLIIWEMA 441
>YES_CANFA (Q28923) Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2)| (p61-Yes) (c-Yes) Length = 538 Score = 31.6 bits (70), Expect = 1.8 Identities = 33/118 (27%), Positives = 48/118 (40%) Frame = -2 Query: 558 IGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAANSSQSYYPSWVYDKLT 379 I + APE + +G + KSDV+SFG+L E+ R P N Y ++ Sbjct: 431 IKWTAPE--AALYGRFTIKSDVWSFGILQTELTTKGRVPYPGMVNREVLEQVERGY-RMP 487 Query: 378 APVVDAVCPVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVIDMLEGGFDGLQMPSRP 205 P CP S+HEL C + +RPT + LE F + +P Sbjct: 488 CP---QGCP-ESLHELMN-------LCWKKDPDERPTFEYIQSFLEDYFTAAEPQYQP 534
>PTK6_MOUSE (Q64434) Tyrosine-protein kinase 6 (EC 2.7.10.2) (SRC-related| intestinal kinase) Length = 451 Score = 31.6 bits (70), Expect = 1.8 Identities = 19/43 (44%), Positives = 26/43 (60%) Frame = -2 Query: 552 YIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAAN 424 + APE +SR G S KSDV+SFG+LL E+ + P +N Sbjct: 353 WTAPEALSR--GHYSIKSDVWSFGVLLHEIFSRGQMPYPGMSN 393
>KOIA_SCHPO (Q9Y7J6) Putative serine/threonine-protein kinase C1778.10c (EC| 2.7.11.1) Length = 550 Score = 31.6 bits (70), Expect = 1.8 Identities = 14/37 (37%), Positives = 24/37 (64%) Frame = -2 Query: 564 GTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGG 454 GT Y+APE++SR +S SD+++F ++ +M G Sbjct: 222 GTAEYVAPELLSRQ--VVSKSSDLWAFACVVYQMIVG 256
>MP2K1_XENLA (Q05116) Dual specificity mitogen-activated protein kinase kinase 1| (EC 2.7.12.2) (MAP kinase kinase 1) (MAPKK 1) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK1) Length = 394 Score = 31.2 bits (69), Expect = 2.3 Identities = 16/43 (37%), Positives = 27/43 (62%) Frame = -2 Query: 564 GTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADP 436 GT Y++PE + + ++ +SD++S G+ L+EMA GR P Sbjct: 224 GTRSYMSPERLQGTHYSV--QSDIWSMGLSLVEMAIGRYPIPP 264
>STE11_YEAST (P23561) Serine/threonine-protein kinase STE11 (EC 2.7.11.1)| Length = 738 Score = 31.2 bits (69), Expect = 2.3 Identities = 12/41 (29%), Positives = 32/41 (78%) Frame = -2 Query: 573 ALRGTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGR 451 +L+G++ +++PE++ ++ A ++K+D++S G +++EM G+ Sbjct: 637 SLQGSVFWMSPEVVKQT--ATTAKADIWSTGCVVIEMFTGK 675
>MATK_MOUSE (P41242) Megakaryocyte-associated tyrosine-protein kinase (EC| 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase NTK) Length = 505 Score = 31.2 bits (69), Expect = 2.3 Identities = 16/32 (50%), Positives = 22/32 (68%) Frame = -2 Query: 558 IGYIAPEMISRSFGAISSKSDVYSFGMLLLEM 463 + + APE + G SSKSDV+SFG+LL E+ Sbjct: 386 VKWTAPEALKN--GRFSSKSDVWSFGVLLWEV 415
>KPCA_RAT (P05696) Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha)| (PKC-A) Length = 671 Score = 31.2 bits (69), Expect = 2.3 Identities = 17/45 (37%), Positives = 26/45 (57%) Frame = -2 Query: 585 VPSRALRGTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGR 451 V +R GT YIAPE+I ++ D +++G+LL EM G+ Sbjct: 492 VTTRTFCGTPDYIAPEII--AYQPYGKSVDWWAYGVLLYEMLAGQ 534
>KPCA_RABIT (P10102) Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha)| (PKC-A) Length = 671 Score = 31.2 bits (69), Expect = 2.3 Identities = 17/45 (37%), Positives = 26/45 (57%) Frame = -2 Query: 585 VPSRALRGTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGR 451 V +R GT YIAPE+I ++ D +++G+LL EM G+ Sbjct: 492 VTTRTFCGTPDYIAPEII--AYQPYGKSVDWWAYGVLLYEMLAGQ 534
>KPCA_MOUSE (P20444) Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha)| (PKC-A) Length = 671 Score = 31.2 bits (69), Expect = 2.3 Identities = 17/45 (37%), Positives = 26/45 (57%) Frame = -2 Query: 585 VPSRALRGTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGR 451 V +R GT YIAPE+I ++ D +++G+LL EM G+ Sbjct: 492 VTTRTFCGTPDYIAPEII--AYQPYGKSVDWWAYGVLLYEMLAGQ 534
>KPCA_HUMAN (P17252) Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha)| (PKC-A) Length = 671 Score = 31.2 bits (69), Expect = 2.3 Identities = 17/45 (37%), Positives = 26/45 (57%) Frame = -2 Query: 585 VPSRALRGTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGR 451 V +R GT YIAPE+I ++ D +++G+LL EM G+ Sbjct: 492 VTTRTFCGTPDYIAPEII--AYQPYGKSVDWWAYGVLLYEMLAGQ 534
>KPCA_BOVIN (P04409) Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha)| (PKC-A) Length = 671 Score = 31.2 bits (69), Expect = 2.3 Identities = 17/45 (37%), Positives = 26/45 (57%) Frame = -2 Query: 585 VPSRALRGTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGR 451 V +R GT YIAPE+I ++ D +++G+LL EM G+ Sbjct: 492 VTTRTFCGTPDYIAPEII--AYQPYGKSVDWWAYGVLLYEMLAGQ 534
>CHK1_YEAST (P38147) Serine/threonine-protein kinase CHK1 (EC 2.7.11.1)| (Checkpoint kinase 1) Length = 527 Score = 31.2 bits (69), Expect = 2.3 Identities = 13/39 (33%), Positives = 25/39 (64%) Frame = -2 Query: 567 RGTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGR 451 RG+ Y+APE++ G + ++D++S G+LL + G+ Sbjct: 181 RGSPPYMAPEVLYSEEGYYADRTDIWSIGILLFVLLTGQ 219
>RIPK4_HUMAN (P57078) Receptor-interacting serine/threonine-protein kinase 4 (EC| 2.7.11.1) (Ankyrin repeat domain protein 3) (PKC-delta-interacting protein kinase) Length = 832 Score = 31.2 bits (69), Expect = 2.3 Identities = 14/33 (42%), Positives = 19/33 (57%) Frame = -2 Query: 570 LRGTIGYIAPEMISRSFGAISSKSDVYSFGMLL 472 L GTI Y+ PE I +K DVYSF +++ Sbjct: 181 LFGTIAYLPPERIREKSRLFDTKHDVYSFAIVI 213
>PHOT2_ARATH (P93025) Phototropin-2 (EC 2.7.11.1) (Defective in chloroplast| avoidance protein 1) (Non phototropic hypocotyl 1-like protein 1) (NPH1-like 1) (AtKin7) Length = 915 Score = 31.2 bits (69), Expect = 2.3 Identities = 23/69 (33%), Positives = 36/69 (52%) Frame = -2 Query: 579 SRALRGTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAANSSQSYYPS 400 S + GT YIAPE+I+ + +S D ++ G+LL EM GR P + Q + + Sbjct: 761 SNSFVGTEEYIAPEIITGA--GHTSAIDWWALGILLYEMLYGR---TPFRGKNRQKTFAN 815 Query: 399 WVYDKLTAP 373 ++ LT P Sbjct: 816 ILHKDLTFP 824
>MATK_RAT (P41243) Megakaryocyte-associated tyrosine-protein kinase (EC| 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase BATK) Length = 467 Score = 31.2 bits (69), Expect = 2.3 Identities = 16/32 (50%), Positives = 22/32 (68%) Frame = -2 Query: 558 IGYIAPEMISRSFGAISSKSDVYSFGMLLLEM 463 + + APE + G SSKSDV+SFG+LL E+ Sbjct: 348 VKWTAPEALKN--GRFSSKSDVWSFGVLLWEV 377
>FGR_HUMAN (P09769) Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2)| (P55-FGR) (C-FGR) Length = 529 Score = 31.2 bits (69), Expect = 2.3 Identities = 17/40 (42%), Positives = 25/40 (62%) Frame = -2 Query: 582 PSRALRGTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEM 463 P + + I + APE + FG + KSDV+SFG+LL E+ Sbjct: 414 PCQGSKFPIKWTAPE--AALFGRFTIKSDVWSFGILLTEL 451
>ST32A_HUMAN (Q8WU08) Serine/threonine-protein kinase 32A (EC 2.7.11.1) (YANK1)| Length = 396 Score = 31.2 bits (69), Expect = 2.3 Identities = 22/67 (32%), Positives = 33/67 (49%), Gaps = 1/67 (1%) Frame = -2 Query: 570 LRGTIGYIAPEMISRSFGA-ISSKSDVYSFGMLLLEMAGGRRNADPNAANSSQSYYPSWV 394 + GT Y+APEM S GA S D +S G+ E+ GRR ++ SS+ ++ Sbjct: 180 MAGTKPYMAPEMFSSRKGAGYSFAVDWWSLGVTAYELLRGRRPYHIRSSTSSKEIVHTFE 239 Query: 393 YDKLTAP 373 +T P Sbjct: 240 TTVVTYP 246
>KPCB_MOUSE (P68404) Protein kinase C beta type (EC 2.7.11.13) (PKC-beta)| (PKC-B) Length = 672 Score = 31.2 bits (69), Expect = 2.3 Identities = 17/45 (37%), Positives = 26/45 (57%) Frame = -2 Query: 585 VPSRALRGTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGR 451 V ++ GT YIAPE+I ++ D ++FG+LL EM G+ Sbjct: 495 VTTKTFCGTPDYIAPEII--AYQPYGKSVDWWAFGVLLYEMLAGQ 537
>KPCB_BOVIN (P05126) Protein kinase C beta type (EC 2.7.11.13) (PKC-beta)| (PKC-B) Length = 672 Score = 31.2 bits (69), Expect = 2.3 Identities = 17/45 (37%), Positives = 26/45 (57%) Frame = -2 Query: 585 VPSRALRGTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGR 451 V ++ GT YIAPE+I ++ D ++FG+LL EM G+ Sbjct: 495 VTTKTFCGTPDYIAPEII--AYQPYGKSVDWWAFGVLLYEMLAGQ 537
>ILPR_BRALA (O02466) Insulin-like peptide receptor precursor (EC 2.7.10.1) (ILP| receptor) [Contains: Insulin-like peptide receptor alpha chain; Insulin-like peptide receptor beta chain] Length = 1363 Score = 31.2 bits (69), Expect = 2.3 Identities = 30/108 (27%), Positives = 50/108 (46%), Gaps = 3/108 (2%) Frame = -2 Query: 558 IGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAANSSQSYYPSWVYDKLT 379 + +++PE S G +S+SDV+S+G++L EM A +SQ Y K Sbjct: 1189 VRWMSPE--SLKVGVFTSQSDVWSYGVVLWEM----------ATLASQPY-----QGKSN 1231 Query: 378 APVVDAVCPVASMHELE---KKLCIVGLWCIQMKSHDRPTMSEVIDML 244 V+ V + + E KL + C Q + RPT E++++L Sbjct: 1232 EEVLKFVIDGGMLEKPEGCPNKLYDLMKLCWQYRQSMRPTFLEIVEIL 1279
>MP2K1_SERCA (Q91447) Dual specificity mitogen-activated protein kinase kinase 1| (EC 2.7.12.2) (MAP kinase kinase 1) (MAPKK 1) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK1) (Fragment) Length = 388 Score = 31.2 bits (69), Expect = 2.3 Identities = 16/43 (37%), Positives = 27/43 (62%) Frame = -2 Query: 564 GTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADP 436 GT Y++PE + + ++ +SD++S G+ L+EMA GR P Sbjct: 218 GTRSYMSPERLQGTHYSV--QSDIWSMGLSLVEMAIGRYPIPP 258
>KPCB_RAT (P68403) Protein kinase C beta type (EC 2.7.11.13) (PKC-beta)| (PKC-B) Length = 670 Score = 31.2 bits (69), Expect = 2.3 Identities = 17/45 (37%), Positives = 26/45 (57%) Frame = -2 Query: 585 VPSRALRGTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGR 451 V ++ GT YIAPE+I ++ D ++FG+LL EM G+ Sbjct: 495 VTTKTFCGTPDYIAPEII--AYQPYGKSVDWWAFGVLLYEMLAGQ 537
>KPCB_RABIT (P05772) Protein kinase C beta type (EC 2.7.11.13) (PKC-beta)| (PKC-B) Length = 670 Score = 31.2 bits (69), Expect = 2.3 Identities = 17/45 (37%), Positives = 26/45 (57%) Frame = -2 Query: 585 VPSRALRGTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGR 451 V ++ GT YIAPE+I ++ D ++FG+LL EM G+ Sbjct: 495 VTTKTFCGTPDYIAPEII--AYQPYGKSVDWWAFGVLLYEMLAGQ 537
>KPCB_HUMAN (P05771) Protein kinase C beta type (EC 2.7.11.13) (PKC-beta)| (PKC-B) Length = 670 Score = 31.2 bits (69), Expect = 2.3 Identities = 17/45 (37%), Positives = 26/45 (57%) Frame = -2 Query: 585 VPSRALRGTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGR 451 V ++ GT YIAPE+I ++ D ++FG+LL EM G+ Sbjct: 495 VTTKTFCGTPDYIAPEII--AYQPYGKSVDWWAFGVLLYEMLAGQ 537
>PMYT1_XENLA (Q91618) Membrane-associated tyrosine- and threonine-specific| cdc2-inhibitory kinase (EC 2.7.11.1) (Myt1 kinase) Length = 548 Score = 31.2 bits (69), Expect = 2.3 Identities = 17/38 (44%), Positives = 23/38 (60%) Frame = -2 Query: 573 ALRGTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMA 460 A G Y+APE++ G S +DV+S GM LLE+A Sbjct: 260 AQEGDPRYMAPELLD---GIFSKAADVFSLGMSLLEVA 294
>KS6A1_RAT (Q63531) Ribosomal protein S6 kinase alpha-1 (EC 2.7.11.1)| (S6K-alpha 1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (Ribosomal S6 kinase 1) (RSK-1) (pp90RSK1) (MAP kinase-activated protein kinase 1a) (MAPKAPK1A) Length = 735 Score = 31.2 bits (69), Expect = 2.3 Identities = 14/37 (37%), Positives = 25/37 (67%) Frame = -2 Query: 564 GTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGG 454 GT+ Y+APE+++R + +D +S+G+L+ EM G Sbjct: 224 GTVEYMAPEVVNRQ--GHTHSADWWSYGVLMFEMLTG 258
>SRK2_SPOLA (P42688) Tyrosine-protein kinase SRK2 (EC 2.7.10.2) (Fragment)| Length = 362 Score = 31.2 bits (69), Expect = 2.3 Identities = 33/109 (30%), Positives = 46/109 (42%) Frame = -2 Query: 558 IGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAANSSQSYYPSWVYDKLT 379 I + APE + F S KSDV+SFG+L+ E+ R P +N+ V L Sbjct: 254 IKWTAPE--AALFNRFSIKSDVWSFGILITELVTYGRIPYPGMSNAE-------VLQNLD 304 Query: 378 APVVDAVCPVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVIDMLEGGF 232 CPV + L + + L C + DRPT + LE F Sbjct: 305 KG-YRMPCPVTTPESLYQ----IMLDCWKRNPADRPTFEALQWRLEDFF 348
>PKN2_COREF (Q8FUI4) Serine/threonine protein kinases drp72 (EC 2.7.11.1)| Length = 520 Score = 31.2 bits (69), Expect = 2.3 Identities = 20/51 (39%), Positives = 27/51 (52%) Frame = -2 Query: 564 GTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAANSSQS 412 GT Y++PE ++ SDVYS G++ EM GRR P +SS S Sbjct: 186 GTAQYVSPEQAQGH--QVTPASDVYSLGVVGYEMLSGRR---PFTGDSSVS 231
>CDC5_YEAST (P32562) Cell cycle serine/threonine-protein kinase CDC5/MSD2 (EC| 2.7.11.21) Length = 705 Score = 31.2 bits (69), Expect = 2.3 Identities = 29/120 (24%), Positives = 54/120 (45%) Frame = -2 Query: 564 GTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAANSSQSYYPSWVYDK 385 GT YIAPE++ S + D++S G++L + G+ N+ +Y++ Sbjct: 241 GTPNYIAPEVLMGKHSGHSFEVDIWSLGVMLYALLIGKPPFQARDVNT--------IYER 292 Query: 384 LTAPVVDAVCPVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVIDMLEGGFDGLQMPSRP 205 + D P E K+ I + + + +RP+++E++D + F G PS P Sbjct: 293 IKCR--DFSFPRDKPISDEGKILIRDI--LSLDPIERPSLTEIMDYV--WFRGTFPPSIP 346
>SRC_AVIST (P14085) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 556 Score = 30.8 bits (68), Expect = 3.1 Identities = 30/106 (28%), Positives = 43/106 (40%) Frame = -2 Query: 558 IGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAANSSQSYYPSWVYDKLT 379 I + APE + +G + KSDV+SFG+LL E+ R P N V D++ Sbjct: 425 IKWTAPE--AALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNRE-------VLDQVE 475 Query: 378 APVVDAVCPVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVIDMLE 241 CP L +C C + +RPT + LE Sbjct: 476 RG-YRMPCPPECPESLHDLMC----QCWRKDPEERPTFEYLQAFLE 516
>RAF_MSV36 (P00532) Serine/threonine-protein kinase transforming protein raf| (EC 2.7.11.1) Length = 323 Score = 30.8 bits (68), Expect = 3.1 Identities = 15/38 (39%), Positives = 26/38 (68%), Gaps = 1/38 (2%) Frame = -2 Query: 564 GTIGYIAPEMIS-RSFGAISSKSDVYSFGMLLLEMAGG 454 G++ ++APE+I + S +SDVYS+G++L E+ G Sbjct: 182 GSVLWMAPEVIRMQDDNPFSFQSDVYSYGIVLYELMAG 219
>PAK7_MOUSE (Q8C015) Serine/threonine-protein kinase PAK 7 (EC 2.7.11.1)| (p21-activated kinase 7) (PAK-7) (p21-activated kinase 5) Length = 719 Score = 30.8 bits (68), Expect = 3.1 Identities = 18/45 (40%), Positives = 30/45 (66%), Gaps = 1/45 (2%) Frame = -2 Query: 585 VPSR-ALRGTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGG 454 VP R +L GT ++APE+ISR ++ D++S G++++EM G Sbjct: 597 VPKRKSLVGTPYWMAPEVISRL--PYGTEVDIWSLGIMVIEMIDG 639
>PAK7_HUMAN (Q9P286) Serine/threonine-protein kinase PAK 7 (EC 2.7.11.1)| (p21-activated kinase 7) (PAK-7) (PAK-5) Length = 719 Score = 30.8 bits (68), Expect = 3.1 Identities = 18/45 (40%), Positives = 30/45 (66%), Gaps = 1/45 (2%) Frame = -2 Query: 585 VPSR-ALRGTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGG 454 VP R +L GT ++APE+ISR ++ D++S G++++EM G Sbjct: 597 VPKRKSLVGTPYWMAPEVISRL--PYGTEVDIWSLGIMVIEMIDG 639
>MIL_AVIMH (P00531) Serine/threonine-protein kinase transforming protein mil| (EC 2.7.11.1) Length = 380 Score = 30.8 bits (68), Expect = 3.1 Identities = 16/38 (42%), Positives = 26/38 (68%), Gaps = 1/38 (2%) Frame = -2 Query: 564 GTIGYIAPEMIS-RSFGAISSKSDVYSFGMLLLEMAGG 454 G+I ++APE+I + S +SDVYS+G++L E+ G Sbjct: 240 GSILWMAPEVIRMQDSNPFSFQSDVYSYGIVLYELMTG 277
>FLK_RAT (P09760) Tyrosine-protein kinase FLK (EC 2.7.10.2) (Fragment)| Length = 323 Score = 30.8 bits (68), Expect = 3.1 Identities = 16/31 (51%), Positives = 23/31 (74%) Frame = -2 Query: 558 IGYIAPEMISRSFGAISSKSDVYSFGMLLLE 466 I + APE ++ +G SS+SDV+SFG+LL E Sbjct: 225 IKWTAPEALN--YGRYSSESDVWSFGILLWE 253
>RIPK1_HUMAN (Q13546) Receptor-interacting serine/threonine-protein kinase 1 (EC| 2.7.11.1) (Serine/threonine-protein kinase RIP) (Cell death protein RIP) (Receptor-interacting protein) Length = 671 Score = 30.8 bits (68), Expect = 3.1 Identities = 35/147 (23%), Positives = 57/147 (38%) Frame = -2 Query: 564 GTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAANSSQSYYPSWVYDK 385 GT+ Y+APE ++ + KSDVYSF ++L + + + NA Q ++ Sbjct: 188 GTLYYMAPEHLNDVNAKPTEKSDVYSFAVVLWAIFANKEPYE-NAICEQQLIMCIKSGNR 246 Query: 384 LTAPVVDAVCPVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVIDMLEGGFDGLQMPSRP 205 + CP +++ + C + RPT F G++ RP Sbjct: 247 PDVDDITEYCP--------REIISLMKLCWEANPEARPT-----------FPGIEEKFRP 287 Query: 204 FFCDDDHTAVPDSYPLLSELTEISEED 124 F+ LS+L E EED Sbjct: 288 FY--------------LSQLEESVEED 300
>KAPA_YEAST (P06244) cAMP-dependent protein kinase type 1 (EC 2.7.11.11) (PKA| 1) (CDC25-suppressing protein kinase) (PK-25) Length = 397 Score = 30.8 bits (68), Expect = 3.1 Identities = 17/39 (43%), Positives = 23/39 (58%) Frame = -2 Query: 570 LRGTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGG 454 L GT YIAPE++S + D +SFG+L+ EM G Sbjct: 242 LCGTPDYIAPEVVSTK--PYNKSIDWWSFGILIYEMLAG 278
>EPHA8_HUMAN (P29322) Ephrin type-A receptor 8 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EEK) (EPH- and ELK-related kinase) (HEK3) Length = 1005 Score = 30.8 bits (68), Expect = 3.1 Identities = 34/111 (30%), Positives = 54/111 (48%), Gaps = 5/111 (4%) Frame = -2 Query: 558 IGYIAPEMISRSFGAISSKSDVYSFGMLLLE-MAGGRR----NADPNAANSSQSYYPSWV 394 I + APE I+ F SS SDV+SFG+++ E +A G R + + +S + Y Sbjct: 802 IRWTAPEAIA--FRTFSSASDVWSFGVVMWEVLAYGERPYWNMTNRDVISSVEEGY---- 855 Query: 393 YDKLTAPVVDAVCPVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVIDMLE 241 +L AP+ CP A +H+L L C RP S+++ +L+ Sbjct: 856 --RLPAPM---GCPHA-LHQLM-------LDCWHKDRAQRPRFSQIVSVLD 893
>ABL_DROME (P00522) Tyrosine-protein kinase Abl (EC 2.7.10.2) (Abelson| protein) (D-ash) Length = 1620 Score = 30.8 bits (68), Expect = 3.1 Identities = 32/109 (29%), Positives = 52/109 (47%) Frame = -2 Query: 558 IGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGGRRNADPNAANSSQSYYPSWVYDKLT 379 I + APE ++ + S+KSDV++FG+LL E+A + P A + + Y+ DK Sbjct: 532 IKWTAPEGLA--YNKFSTKSDVWAFGVLLWEIATYGMSPYP-AIDLTDVYHK---LDKGY 585 Query: 378 APVVDAVCPVASMHELEKKLCIVGLWCIQMKSHDRPTMSEVIDMLEGGF 232 CP +++L ++ C Q + DRPT + LE F Sbjct: 586 RMERPPGCP-PEVYDLMRQ-------CWQWDATDRPTFKSIHHALEHMF 626
>SRMS_MOUSE (Q62270) Tyrosine-protein kinase Srms (EC 2.7.10.2) (PTK70)| Length = 496 Score = 30.8 bits (68), Expect = 3.1 Identities = 16/42 (38%), Positives = 26/42 (61%) Frame = -2 Query: 588 FVPSRALRGTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEM 463 + PS + + + APE + ++ S KSDV+SFG+LL E+ Sbjct: 384 YSPSSGSKIPVKWTAPE--AANYRVFSQKSDVWSFGILLYEV 423
>KAPC_YEAST (P05986) cAMP-dependent protein kinase type 3 (EC 2.7.11.11) (PKA| 3) Length = 398 Score = 30.8 bits (68), Expect = 3.1 Identities = 17/39 (43%), Positives = 23/39 (58%) Frame = -2 Query: 570 LRGTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMAGG 454 L GT YIAPE++S + D +SFG+L+ EM G Sbjct: 243 LCGTPDYIAPEVVSTK--PYNKSVDWWSFGVLIYEMLAG 279
>RAF1_MOUSE (Q99N57) RAF proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (Raf-1) (C-RAF) (cRaf) Length = 648 Score = 30.8 bits (68), Expect = 3.1 Identities = 15/38 (39%), Positives = 26/38 (68%), Gaps = 1/38 (2%) Frame = -2 Query: 564 GTIGYIAPEMIS-RSFGAISSKSDVYSFGMLLLEMAGG 454 G++ ++APE+I + S +SDVYS+G++L E+ G Sbjct: 507 GSVLWMAPEVIRMQDDNPFSFQSDVYSYGIVLYELMAG 544
>PMYT1_MOUSE (Q9ESG9) Membrane-associated tyrosine- and threonine-specific| cdc2-inhibitory kinase (EC 2.7.11.1) (Myt1 kinase) Length = 490 Score = 30.8 bits (68), Expect = 3.1 Identities = 15/38 (39%), Positives = 25/38 (65%) Frame = -2 Query: 573 ALRGTIGYIAPEMISRSFGAISSKSDVYSFGMLLLEMA 460 A G Y+APE++ S+G + +DV+S G+ +LE+A Sbjct: 257 AQEGDPRYMAPELLQGSYG---TAADVFSLGLTILEVA 291 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 89,397,894 Number of Sequences: 219361 Number of extensions: 1880209 Number of successful extensions: 5562 Number of sequences better than 10.0: 369 Number of HSP's better than 10.0 without gapping: 5326 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 5527 length of database: 80,573,946 effective HSP length: 106 effective length of database: 57,321,680 effective search space used: 5158951200 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
