ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | rbah61f10 |
|---|---|
| Clone Library Name | barley_pub |
>PM34_HUMAN (O43808) Peroxisomal membrane protein PMP34 (34 kDa peroxisomal| membrane protein) (Solute carrier family 25 member 17) Length = 307 Score = 108 bits (269), Expect = 2e-23 Identities = 63/167 (37%), Positives = 98/167 (58%), Gaps = 7/167 (4%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGLIPTLIMVCNPSIQFMIYETLSKRLQSKRSGKRFPKKNI 421 G I A ++ R+ GIS W G P+L++V NP+IQFM YE L ++L KR + Sbjct: 148 GIIDAFHQIIRDEGISALWNGTFPSLLLVFNPAIQFMFYEGLKRQLLKKR-------MKL 200 Query: 420 TAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGR---NAASRYTGTLDAIL----K 262 ++++VF++GA+AK AT VTYPL V+S L+ GR N +R G+L IL + Sbjct: 201 SSLDVFIIGAVAKAIATTVTYPLQTVQSILR----FGRHRLNPENRTLGSLRNILYLLHQ 256 Query: 261 MIRYEGLHGFYKGMGTKIVQSVFAASVLFMVKEELVKFVILLVARSR 121 +R G+ G YKG+ K++Q+V A+++F+V E+L ++ R Sbjct: 257 RVRRFGIMGLYKGLEAKLLQTVLTAALMFLVYEKLTAATFTVMGLKR 303 Score = 44.3 bits (103), Expect = 3e-04 Identities = 37/150 (24%), Positives = 69/150 (46%), Gaps = 3/150 (2%) Frame = -3 Query: 597 TIQAIREVYRESGISGFWKGLIPTLIMVCNPSIQFMIYETLSKRLQSKRSGKRFPKKNIT 418 T + E+ +E G+ ++G P + +C + + K L K ++ T Sbjct: 48 THMVLLEIIKEEGLLAPYRGWFPVISSLCCSNFVYFYTFNSLKALWVKG-------QHST 100 Query: 417 AMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRN---AASRYTGTLDAILKMIRYE 247 + ++G +A + ++T PL VV +RL+ + RN + Y G +DA ++IR E Sbjct: 101 TGKDLVVGFVAGVVNVLLTTPLWVVNTRLKLQGAKFRNEDIVPTNYKGIIDAFHQIIRDE 160 Query: 246 GLHGFYKGMGTKIVQSVFAASVLFMVKEEL 157 G+ + G ++ VF ++ FM E L Sbjct: 161 GISALWNGTFPSLL-LVFNPAIQFMFYEGL 189
>PM34_MOUSE (O70579) Peroxisomal membrane protein PMP34 (34 kDa peroxisomal| membrane protein) (Solute carrier family 25 member 17) Length = 307 Score = 104 bits (260), Expect = 2e-22 Identities = 59/155 (38%), Positives = 93/155 (60%), Gaps = 7/155 (4%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGLIPTLIMVCNPSIQFMIYETLSKRLQSKRSGKRFPKKNI 421 G I A ++ R+ GI W G P+L++V NP+IQFM YE L ++L KR + Sbjct: 148 GIIDAFHQIIRDEGILALWNGTFPSLLLVFNPAIQFMFYEGLKRQLLKKR-------MKL 200 Query: 420 TAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGR---NAASRYTGTLDAILKMIRY 250 ++++VF++GAIAK AT VTYP+ V+S L+ GR N +R G+L +L ++ Sbjct: 201 SSLDVFIIGAIAKAIATTVTYPMQTVQSILR----FGRHRLNPENRTLGSLRNVLSLLHQ 256 Query: 249 E----GLHGFYKGMGTKIVQSVFAASVLFMVKEEL 157 G+ G YKG+ K++Q+V A+++F+V E+L Sbjct: 257 RVKRFGIMGLYKGLEAKLLQTVLTAALMFLVYEKL 291 Score = 42.0 bits (97), Expect = 0.001 Identities = 38/150 (25%), Positives = 73/150 (48%), Gaps = 3/150 (2%) Frame = -3 Query: 597 TIQAIREVYRESGISGFWKGLIPTLIMVCNPSIQFMIYETLSKRLQSKRSGKRFPKKNIT 418 T + E+ +E G+ ++G P + +C + F+ + T + G+R + T Sbjct: 48 THAVLLEIIKEEGLLAPYRGWFPVISSLCCSN--FVYFYTFNSLKAVWVKGQR----SST 101 Query: 417 AMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNA---ASRYTGTLDAILKMIRYE 247 ++ ++G +A + ++T PL VV +RL+ + RN + Y G +DA ++IR E Sbjct: 102 GKDL-VVGFVAGVVNVLLTTPLWVVNTRLKLQGAKFRNEDIIPTNYKGIIDAFHQIIRDE 160 Query: 246 GLHGFYKGMGTKIVQSVFAASVLFMVKEEL 157 G+ + G ++ VF ++ FM E L Sbjct: 161 GILALWNGTFPSLL-LVFNPAIQFMFYEGL 189
>MFTC_MACFA (Q95J75) Mitochondrial folate transporter/carrier (Solute carrier| family 25 member 32) Length = 315 Score = 89.4 bits (220), Expect = 8e-18 Identities = 47/153 (30%), Positives = 83/153 (54%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGLIPTLIMVCNPSIQFMIYETLSKRLQSKRSGKRFPKKNI 421 G + ++Y+ G+ G +KG +P L + ++QFM YE L +L+ + R P+ + Sbjct: 165 GMFDTLVKIYKYEGVRGLYKGFVPGLFGTSHGALQFMAYELL--KLKYNQHINRLPEAQL 222 Query: 420 TAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGL 241 + +E + A++K+ A TYP VV++RLQ + Y+G +D I K R EG+ Sbjct: 223 STVEYISVAALSKIFAVAATYPYQVVRARLQDQHMF-------YSGVIDVITKTWRKEGI 275 Query: 240 HGFYKGMGTKIVQSVFAASVLFMVKEELVKFVI 142 GFYKG+ +++ A + F+V E + F++ Sbjct: 276 GGFYKGIAPNLIRVTPACCITFVVYENVSHFLL 308 Score = 52.4 bits (124), Expect = 1e-06 Identities = 33/127 (25%), Positives = 62/127 (48%), Gaps = 1/127 (0%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGLIPTLIMVCNPSIQFMIYETLSKRLQSKRSGKRFPKKNI 421 G + + +++ G+ G ++G+ P V + + +Y ++S ++ R + + Sbjct: 64 GILHCLTTIWKLDGLRGLYQGVTPN---VWGAGLSWGLYFFFYNAIKSYKTEGR--AERL 118 Query: 420 TAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASR-YTGTLDAILKMIRYEG 244 A E + A A +T PL V K+RL + + N+ R Y G D ++K+ +YEG Sbjct: 119 EATEYLVSAAEAGAMTLCITNPLWVTKTRLMLQYDAVINSPHRQYKGMFDTLVKIYKYEG 178 Query: 243 LHGFYKG 223 + G YKG Sbjct: 179 VRGLYKG 185
>MFTC_HUMAN (Q9H2D1) Mitochondrial folate transporter/carrier (Solute carrier| family 25 member 32) Length = 315 Score = 89.0 bits (219), Expect = 1e-17 Identities = 47/153 (30%), Positives = 83/153 (54%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGLIPTLIMVCNPSIQFMIYETLSKRLQSKRSGKRFPKKNI 421 G + ++Y+ G+ G +KG +P L + ++QFM YE L +L+ + R P+ + Sbjct: 165 GMFDTLVKIYKYEGVRGLYKGFVPGLFGTSHGALQFMAYELL--KLKYNQHINRLPEAQL 222 Query: 420 TAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGL 241 + +E + A++K+ A TYP VV++RLQ + Y+G +D I K R EG+ Sbjct: 223 STVEYISVAALSKIFAVAATYPYQVVRARLQDQHMF-------YSGVIDVITKTWRKEGV 275 Query: 240 HGFYKGMGTKIVQSVFAASVLFMVKEELVKFVI 142 GFYKG+ +++ A + F+V E + F++ Sbjct: 276 GGFYKGIAPNLIRVTPACCITFVVYENVSHFLL 308 Score = 52.0 bits (123), Expect = 1e-06 Identities = 32/127 (25%), Positives = 62/127 (48%), Gaps = 1/127 (0%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGLIPTLIMVCNPSIQFMIYETLSKRLQSKRSGKRFPKKNI 421 G + + +++ G+ G ++G+ P + + + +Y ++S ++ R + + Sbjct: 64 GILHCLTTIWKLDGLRGLYQGVTPN---IWGAGLSWGLYFFFYNAIKSYKTEGR--AERL 118 Query: 420 TAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASR-YTGTLDAILKMIRYEG 244 A E + A A +T PL V K+RL + + N+ R Y G D ++K+ +YEG Sbjct: 119 EATEYLVSAAEAGAMTLCITNPLWVTKTRLMLQYDAVVNSPHRQYKGMFDTLVKIYKYEG 178 Query: 243 LHGFYKG 223 + G YKG Sbjct: 179 VRGLYKG 185
>PM47B_CANBO (Q00319) Peroxisomal membrane protein PMP47B| Length = 419 Score = 87.8 bits (216), Expect = 2e-17 Identities = 55/187 (29%), Positives = 88/187 (47%), Gaps = 39/187 (20%) Frame = -3 Query: 597 TIQAIREVYRESGISGFWKGLIPTLIMVCNPSIQFMIYETLSKRLQSKRSGKRFPKKNIT 418 TI+AI + + G + G++P L +V NP IQ+ I+E L + + K+N+T Sbjct: 187 TIEAIIYILKNEGWQKLFTGIVPALFLVLNPIIQYTIFEQLKSFIV------KIKKRNVT 240 Query: 417 AMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASR------------------ 292 ++ LLGA KL AT++TYP + ++SR+ K N S Sbjct: 241 PVDALLLGAFGKLIATIITYPYITLRSRMHVKSMTENNEDSEKERTDSVQSLPEDGSDED 300 Query: 291 ------YTGTLDAIL---------------KMIRYEGLHGFYKGMGTKIVQSVFAASVLF 175 Y T++ I+ KM + EG+ FY+G+ K++QS+ A+ LF Sbjct: 301 NSKENPYAETINKIISKLPSPIVSMFIIGYKMYKEEGVSSFYRGLSVKLLQSILNAAFLF 360 Query: 174 MVKEELV 154 KEEL+ Sbjct: 361 YFKEELL 367
>MFTC_MOUSE (Q8BMG8) Mitochondrial folate transporter/carrier (Solute carrier| family 25 member 32) Length = 316 Score = 87.0 bits (214), Expect = 4e-17 Identities = 48/152 (31%), Positives = 80/152 (52%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGLIPTLIMVCNPSIQFMIYETLSKRLQSKRSGKRFPKKNI 421 G A+ ++Y+ G+ G +KG +P L + ++QFM YE L +L+ + R P+ + Sbjct: 165 GMFDALVKIYKYEGVRGLYKGFVPGLFGTSHGALQFMAYELL--KLKYNKHINRLPEAQL 222 Query: 420 TAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGL 241 + E + A++K+ A TYP VV++RLQ + Y G D I K R EG+ Sbjct: 223 STAEYISVAALSKIFAVAATYPYQVVRARLQDQHV-------SYGGVTDVITKTWRKEGI 275 Query: 240 HGFYKGMGTKIVQSVFAASVLFMVKEELVKFV 145 GFYKG+ +++ A + F+V E + F+ Sbjct: 276 GGFYKGIAPNLIRVTPACCITFVVYENVSHFL 307 Score = 50.8 bits (120), Expect = 3e-06 Identities = 31/127 (24%), Positives = 62/127 (48%), Gaps = 1/127 (0%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGLIPTLIMVCNPSIQFMIYETLSKRLQSKRSGKRFPKKNI 421 G + + +++ G+ G ++G+ P V + + +Y ++S ++ R + + Sbjct: 64 GILHCLATIWKVDGLRGLYQGVTPN---VWGAGLSWGLYFFFYNAIKSYKTEGR--AEQL 118 Query: 420 TAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQE-IGRNAASRYTGTLDAILKMIRYEG 244 +E + A A +T PL V K+RL + + + +Y G DA++K+ +YEG Sbjct: 119 EPLEYLVSAAEAGAMTLCITNPLWVTKTRLMLQYGGVASPSQRQYKGMFDALVKIYKYEG 178 Query: 243 LHGFYKG 223 + G YKG Sbjct: 179 VRGLYKG 185
>PM47A_CANBO (P21245) Peroxisomal membrane protein PMP47A| Length = 423 Score = 84.7 bits (208), Expect = 2e-16 Identities = 57/191 (29%), Positives = 89/191 (46%), Gaps = 43/191 (22%) Frame = -3 Query: 597 TIQAIREVYRESGISGFWKGLIPTLIMVCNPSIQFMIYETLSKRLQSKRSGKRFPKKNIT 418 TI+AI + + G + G++P L +V NP IQ+ I+E L + + K+NIT Sbjct: 187 TIEAIIYILKNEGWQKLFTGIVPALFLVLNPIIQYTIFEQLKSFIV------KIKKRNIT 240 Query: 417 AMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQ--EIGRN-------------------- 304 ++ LLGA KL AT++TYP + ++SR+ K EI + Sbjct: 241 PVDALLLGAFGKLIATIITYPYITLRSRMHVKSMTEISEDVEKERTDSVQSLPEDGSDED 300 Query: 303 ------AASRYTGTLDAILK---------------MIRYEGLHGFYKGMGTKIVQSVFAA 187 A S Y T+ I+ M + EG+ FY+G+ K++QS+ A Sbjct: 301 NLKENSAKSPYAETITKIISKLPSPIVSMFTLGYGMYKEEGVSSFYRGLSVKLLQSILNA 360 Query: 186 SVLFMVKEELV 154 + LF KEEL+ Sbjct: 361 AFLFYFKEELL 371
>ANT1_YEAST (Q06497) Peroxisomal adenine nucleotide transporter 1| Length = 328 Score = 81.6 bits (200), Expect = 2e-15 Identities = 50/167 (29%), Positives = 92/167 (55%), Gaps = 2/167 (1%) Frame = -3 Query: 585 IREVYRESG--ISGFWKGLIPTLIMVCNPSIQFMIYETLSKRLQSKRSGKRFPKKNITAM 412 I+++YRE+ I+ FWKGL L + NPSI + ++ L + S +++A+ Sbjct: 167 IKDIYRENNGDITAFWKGLRTGLALTINPSITYASFQRLKEVFFHDHSNDA---GSLSAV 223 Query: 411 EVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGF 232 + F+LG ++K+ +T+VT PL+V K+ LQ+ A S++T +A+L + + EGL Sbjct: 224 QNFILGVLSKMISTLVTQPLIVAKAMLQS-------AGSKFTTFQEALLYLYKNEGLKSL 276 Query: 231 YKGMGTKIVQSVFAASVLFMVKEELVKFVILLVARSRTLLLTRSNKR 91 +KG+ ++ + V +LF + EL K + L+ + L + +R Sbjct: 277 WKGVLPQLTKGVIVQGLLFAFRGELTKSLKRLIFLYSSFFLKHNGQR 323 Score = 36.2 bits (82), Expect = 0.077 Identities = 23/89 (25%), Positives = 41/89 (46%), Gaps = 9/89 (10%) Frame = -3 Query: 414 MEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAAS---------RYTGTLDAILK 262 +E L GA+A A + YPL + K+ +Q++ + S RY +D ++ Sbjct: 4 LESALTGAVASAMANIAVYPLDLSKTIIQSQVSPSSSEDSNEGKVLPNRRYKNVVDCMIN 63 Query: 261 MIRYEGLHGFYKGMGTKIVQSVFAASVLF 175 + + +G+ G Y+GM V + V F Sbjct: 64 IFKEKGILGLYQGMTVTTVATFVQNFVYF 92
>ANT1_ASHGO (Q75A82) Peroxisomal adenine nucleotide transporter 1| Length = 340 Score = 75.5 bits (184), Expect = 1e-13 Identities = 51/167 (30%), Positives = 85/167 (50%), Gaps = 3/167 (1%) Frame = -3 Query: 582 REVYRESGISGFWKGLIPTLIMVCNPSIQFMIYETLSKRLQSKRSGKRFPKKNITAM--- 412 REV+ E+G GFW GL +L++ NPSI + YE L + L + + + Sbjct: 180 REVHAENGWRGFWAGLKVSLVLTVNPSITYATYERLREALFPTPAAASHLVDSAALLSPG 239 Query: 411 EVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGF 232 + F++G ++K+ +TV+T PL++ K+ LQ + S + + + EG Sbjct: 240 QNFVMGVLSKIVSTVLTQPLIIAKASLQ-------RSGSCFQDFHQVLHHLYSTEGPLSL 292 Query: 231 YKGMGTKIVQSVFAASVLFMVKEELVKFVILLVARSRTLLLTRSNKR 91 +KG+G +I + V +LFM K EL K + L+ L L RS++R Sbjct: 293 WKGLGPQITKGVLVQGLLFMFKGELTKMLRKLMF---YLALLRSSRR 336 Score = 36.6 bits (83), Expect = 0.059 Identities = 27/99 (27%), Positives = 43/99 (43%), Gaps = 28/99 (28%) Frame = -3 Query: 417 AMEVFLLGAIAKLGATVVTYPLLVVKSRLQ---------AKQEIGRN------------- 304 + E ++GA A A + YPL + K+ +Q A +E G Sbjct: 2 SFENAVIGATASSLANIAVYPLDLAKTLVQTQLKDEFVEAGEEAGEERAGSRRQNRIKPI 61 Query: 303 ------AASRYTGTLDAILKMIRYEGLHGFYKGMGTKIV 205 AA +Y G LDA+ ++ EG+ G Y+G+G+ V Sbjct: 62 ALRSPQAAEQYKGALDALQRIYGAEGVAGLYRGLGSSTV 100
>YEA6_YEAST (P39953) Putative mitochondrial carrier YEL006W| Length = 335 Score = 73.9 bits (180), Expect = 3e-13 Identities = 47/153 (30%), Positives = 80/153 (52%), Gaps = 1/153 (0%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGLIPTLIMVCNPSIQFMIYETLSKRL-QSKRSGKRFPKKN 424 GTI R++ ++ G + GL+P L+ + N +IQF +YE L R S+ + + Sbjct: 181 GTIDTFRKIIQQEGAKALYAGLVPALLGMLNVAIQFPLYENLKIRFGYSESTDVSTDVTS 240 Query: 423 ITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEG 244 ++ L ++K+ A+ VTYP ++++R+Q K ++ N R+ L I R EG Sbjct: 241 SNFQKLILASMLSKMVASTVTYPHEILRTRMQLKSDL-PNTVQRH--LLPLIKITYRQEG 297 Query: 243 LHGFYKGMGTKIVQSVFAASVLFMVKEELVKFV 145 GFY G T +V++V AA V + E K++ Sbjct: 298 FAGFYSGFATNLVRTVPAAVVTLVSFEYSKKYL 330 Score = 53.5 bits (127), Expect = 5e-07 Identities = 39/122 (31%), Positives = 61/122 (50%), Gaps = 3/122 (2%) Frame = -3 Query: 576 VYRESGISGFWKGLIPTLI-MVCNPSIQFMIYETLSKRLQSKRSGKRFPKKNI--TAMEV 406 ++++ G +G +KGL PT++ + I F +Y+ K S FP A Sbjct: 91 IFKDEGAAGLYKGLQPTVLGYIPTLMIYFSVYDFCRKY-----SVDIFPHSPFLSNASSA 145 Query: 405 FLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFYK 226 GAI+ TV T P+ VVK+RL + IG+ + + Y GT+D K+I+ EG Y Sbjct: 146 ITAGAIS----TVATNPIWVVKTRLMLQTGIGKYS-THYKGTIDTFRKIIQQEGAKALYA 200 Query: 225 GM 220 G+ Sbjct: 201 GL 202 Score = 33.9 bits (76), Expect = 0.38 Identities = 23/98 (23%), Positives = 44/98 (44%), Gaps = 1/98 (1%) Frame = -3 Query: 432 KKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQ-EIGRNAASRYTGTLDAILKMI 256 KKN + GA++ + ++ P V K+RLQA+ + + + Y G + Sbjct: 33 KKNADPRVAAISGALSGALSAMLVCPFDVAKTRLQAQGLQNMTHQSQHYKGFFGTFATIF 92 Query: 255 RYEGLHGFYKGMGTKIVQSVFAASVLFMVKEELVKFVI 142 + EG G YKG+ ++ + + F V + K+ + Sbjct: 93 KDEGAAGLYKGLQPTVLGYIPTLMIYFSVYDFCRKYSV 130
>BT1_MAIZE (P29518) Protein brittle-1, chloroplast precursor| Length = 436 Score = 71.2 bits (173), Expect = 2e-12 Identities = 48/150 (32%), Positives = 80/150 (53%), Gaps = 1/150 (0%) Frame = -3 Query: 588 AIREVYRESGISGFWKGLIPTLI-MVCNPSIQFMIYETLSKRLQSKRSGKRFPKKNITAM 412 A ++ R+ G S ++GL P+LI +V + F YETL KRL + +G+R P ++ + Sbjct: 270 AFVKILRDEGPSELYRGLTPSLIGVVPYAACNFYAYETL-KRLYRRATGRR-PGADVGPV 327 Query: 411 EVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGF 232 L+G+ A A+ T+PL V + ++Q GR Y L AI +++ EG G Sbjct: 328 ATLLIGSAAGAIASSATFPLEVARKQMQVGAVGGRQV---YQNVLHAIYCILKKEGAGGL 384 Query: 231 YKGMGTKIVQSVFAASVLFMVKEELVKFVI 142 Y+G+G ++ + AA + FM E K ++ Sbjct: 385 YRGLGPSCIKLMPAAGIAFMCYEACKKILV 414 Score = 47.4 bits (111), Expect = 3e-05 Identities = 36/141 (25%), Positives = 68/141 (48%), Gaps = 1/141 (0%) Frame = -3 Query: 576 VYRESGISGFWKGLIPTLIMVC-NPSIQFMIYETLSKRLQSKRSGKRFPKKNITAMEVFL 400 + + G +G ++G ++ V + +I+ Y+T K L K G PK I + Sbjct: 179 IMQNEGWTGLFRGNAVNVLRVAPSKAIEHFTYDTAKKFLTPK--GDEPPK--IPIPTPLV 234 Query: 399 LGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFYKGM 220 GA+A +T+ TYP+ ++K+R+ ++++ Y A +K++R EG Y+G+ Sbjct: 235 AGALAGFASTLCTYPMELIKTRVTIEKDV-------YDNVAHAFVKILRDEGPSELYRGL 287 Query: 219 GTKIVQSVFAASVLFMVKEEL 157 ++ V A+ F E L Sbjct: 288 TPSLIGVVPYAACNFYAYETL 308
>TXTP_BOVIN (P79110) Tricarboxylate transport protein, mitochondrial precursor| (Citrate transport protein) (CTP) (Tricarboxylate carrier protein) (Solute carrier family 25 member 1) Length = 311 Score = 70.5 bits (171), Expect = 4e-12 Identities = 44/153 (28%), Positives = 78/153 (50%), Gaps = 1/153 (0%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGLIPTLIMV-CNPSIQFMIYETLSKRLQSKRSGKRFPKKN 424 G +RE+ RE G+ G ++GL T++ N I+F + +L + P K Sbjct: 163 GFFHGVREIVREQGLKGTYQGLTATVLKQGSNQGIRFFVMTSLRNWYRGDN-----PNKP 217 Query: 423 ITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEG 244 + + + GAIA + PL V+K+R+Q + A +Y TLD L+++R EG Sbjct: 218 MNPLITGVFGAIAGAASVFGNTPLDVIKTRMQGLE------AHKYRNTLDCGLQILRNEG 271 Query: 243 LHGFYKGMGTKIVQSVFAASVLFMVKEELVKFV 145 L FYKG ++ + +++F++ +E+VK + Sbjct: 272 LKAFYKGTVPRLGRVCLDVAIVFIIYDEVVKLL 304 Score = 40.4 bits (93), Expect = 0.004 Identities = 33/150 (22%), Positives = 66/150 (44%), Gaps = 2/150 (1%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGLIPTLI-MVCNPSIQFMIYETLSKRLQSKRSGKRFPKKN 424 G +R+ R G+ G ++GL L + +++F +E LS ++ + Sbjct: 66 GIGDCVRQTVRSHGLLGLYRGLSSLLYGSIPKAAVRFGTFEFLSNHMRDAQG-------R 118 Query: 423 ITAMEVFLLGAIAKLG-ATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYE 247 + + L G A + A VV P+ +K + Q +A+ +Y G + +++R + Sbjct: 119 LDSTRGLLCGLGAGVPEAVVVVCPMETIKVKFIHDQT---SASPKYRGFFHGVREIVREQ 175 Query: 246 GLHGFYKGMGTKIVQSVFAASVLFMVKEEL 157 GL G Y+G+ +++ + F V L Sbjct: 176 GLKGTYQGLTATVLKQGSNQGIRFFVMTSL 205 Score = 40.0 bits (92), Expect = 0.005 Identities = 24/79 (30%), Positives = 41/79 (51%) Frame = -3 Query: 411 EVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGF 232 + L G +A +T+P VK++LQ + R+ RY G D + + +R GL G Sbjct: 27 KAILAGGLAGGIEICITFPTEYVKTQLQLDE---RSHPPRYRGIGDCVRQTVRSHGLLGL 83 Query: 231 YKGMGTKIVQSVFAASVLF 175 Y+G+ + + S+ A+V F Sbjct: 84 YRGLSSLLYGSIPKAAVRF 102
>YIA6_YEAST (P40556) Putative mitochondrial carrier YIL006W| Length = 373 Score = 69.7 bits (169), Expect = 6e-12 Identities = 39/140 (27%), Positives = 74/140 (52%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGLIPTLIMVCNPSIQFMIYETLSKRLQSKRSGKRFPKKNI 421 GT A R+++ + G + GL+P+L+ + + +I F IYE L R + +I Sbjct: 219 GTFDAFRKLFYQEGFKALYAGLVPSLLGLFHVAIHFPIYEDLKVRFHC--YSRENNTNSI 276 Query: 420 TAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGL 241 + + +++K+ A+ VTYP ++++R+Q K +I + R + A EGL Sbjct: 277 NLQRLIMASSVSKMIASAVTYPHEILRTRMQLKSDIPDSIQRRLFPLIKATYAQ---EGL 333 Query: 240 HGFYKGMGTKIVQSVFAASV 181 GFY G T +V+++ A+++ Sbjct: 334 KGFYSGFTTNLVRTIPASAI 353 Score = 56.6 bits (135), Expect = 6e-08 Identities = 44/154 (28%), Positives = 75/154 (48%), Gaps = 4/154 (2%) Frame = -3 Query: 606 PY--GTIQAIREVYRESGISGFWKGLIPTLIMVCNPS--IQFMIYETLSKRLQSKRSGKR 439 PY G + + + R+ G G +KGL+P +++ P+ I F +YE K Sbjct: 117 PYYRGIMGTLSTIVRDEGPRGLYKGLVP-IVLGYFPTWMIYFSVYEFSKKFFHGI----- 170 Query: 438 FPKKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKM 259 FP+ + A + A A +T +T P+ VVK+RL + +G + + Y GT DA K+ Sbjct: 171 FPQFDFVAQSCAAITAGA--ASTTLTNPIWVVKTRLMLQSNLGEHP-THYKGTFDAFRKL 227 Query: 258 IRYEGLHGFYKGMGTKIVQSVFAASVLFMVKEEL 157 EG Y G+ ++ +F ++ F + E+L Sbjct: 228 FYQEGFKALYAGLVPSLL-GLFHVAIHFPIYEDL 260 Score = 37.7 bits (86), Expect = 0.027 Identities = 28/84 (33%), Positives = 39/84 (46%) Frame = -3 Query: 402 LLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFYKG 223 L GA A + V PL V K+RLQA+ R Y G + + ++R EG G YKG Sbjct: 82 LSGAFAGFLSGVAVCPLDVAKTRLQAQGLQTRFENPYYRGIMGTLSTIVRDEGPRGLYKG 141 Query: 222 MGTKIVQSVFAASVLFMVKEELVK 151 + IV F +++ E K Sbjct: 142 L-VPIVLGYFPTWMIYFSVYEFSK 164
>FLX1_YEAST (P40464) Mitochondrial FAD carrier protein FLX1| Length = 311 Score = 68.2 bits (165), Expect = 2e-11 Identities = 39/144 (27%), Positives = 77/144 (53%), Gaps = 1/144 (0%) Frame = -3 Query: 585 IREVYRESGISGFWKGLIPTLIMVCNPSIQFMIYETLSKRLQSKRSGKRFPKKNITAMEV 406 ++++ R G G WKGL+P L V ++ F +Y+TL +R + +R + ++T +E Sbjct: 171 VQQLLRTDGFQGLWKGLVPALFGVSQGALYFAVYDTLKQR-KLRRKRENGLDIHLTNLET 229 Query: 405 FLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKM-IRYEGLHGFY 229 + ++ K+ + + YP ++KS LQ+ + A+ L ++K+ I +G G Y Sbjct: 230 IEITSLGKMVSVTLVYPFQLLKSNLQSFR------ANEQKFRLFPLIKLIIANDGFVGLY 283 Query: 228 KGMGTKIVQSVFAASVLFMVKEEL 157 KG+ +V+++ + + F V E L Sbjct: 284 KGLSANLVRAIPSTCITFCVYENL 307 Score = 42.0 bits (97), Expect = 0.001 Identities = 41/184 (22%), Positives = 78/184 (42%), Gaps = 15/184 (8%) Frame = -3 Query: 603 YGTIQAIREVYRESGISG------FWKGLIPTLI-MVCNPSIQF--------MIYETLSK 469 YG I+E+ R S SG ++GL L + F +IY++++K Sbjct: 49 YGPFMVIKEIIRSSANSGRSVTNELYRGLSINLFGNAIAWGVYFGLYGVTKELIYKSVAK 108 Query: 468 RLQSKRSGKRFPKKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRY 289 +++ G K + ++ GA + L ++T P+ V+K+R+ + + A Y Sbjct: 109 PGETQLKGVGNDHK-MNSLIYLSAGASSGLMTAILTNPIWVIKTRIMS---TSKGAQGAY 164 Query: 288 TGTLDAILKMIRYEGLHGFYKGMGTKIVQSVFAASVLFMVKEELVKFVILLVARSRTLLL 109 T + + +++R +G G +KG+ LF V + + F + + R L Sbjct: 165 TSMYNGVQQLLRTDGFQGLWKGL----------VPALFGVSQGALYFAVYDTLKQRKLRR 214 Query: 108 TRSN 97 R N Sbjct: 215 KREN 218
>TXTP_HUMAN (P53007) Tricarboxylate transport protein, mitochondrial precursor| (Citrate transport protein) (CTP) (Tricarboxylate carrier protein) (Solute carrier family 25 member 1) Length = 311 Score = 67.4 bits (163), Expect = 3e-11 Identities = 42/153 (27%), Positives = 78/153 (50%), Gaps = 1/153 (0%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGLIPTLIMV-CNPSIQFMIYETLSKRLQSKRSGKRFPKKN 424 G +RE+ RE G+ G ++GL T++ N +I+F + +L + P K Sbjct: 163 GFFHGVREIVREQGLKGTYQGLTATVLKQGSNQAIRFFVMTSLRNWYRGDN-----PNKP 217 Query: 423 ITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEG 244 + + + GAIA + PL V+K+R+Q + A +Y T D L++++ EG Sbjct: 218 MNPLITGVFGAIAGAASVFGNTPLDVIKTRMQGLE------AHKYRNTWDCGLQILKKEG 271 Query: 243 LHGFYKGMGTKIVQSVFAASVLFMVKEELVKFV 145 L FYKG ++ + +++F++ +E+VK + Sbjct: 272 LKAFYKGTVPRLGRVCLDVAIVFVIYDEVVKLL 304 Score = 39.7 bits (91), Expect = 0.007 Identities = 32/150 (21%), Positives = 66/150 (44%), Gaps = 2/150 (1%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGLIPTLI-MVCNPSIQFMIYETLSKRLQSKRSGKRFPKKN 424 G +R+ R G+ G ++GL L + +++F ++E LS ++ + Sbjct: 66 GIGDCVRQTVRSHGVLGLYRGLSSLLYGSIPKAAVRFGMFEFLSNHMRDAQG-------R 118 Query: 423 ITAMEVFLLGAIAKLG-ATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYE 247 + + L G A + A VV P+ +K + Q + +Y G + +++R + Sbjct: 119 LDSTRGLLCGLGAGVAEAVVVVCPMETIKVKFIHDQT---SPNPKYRGFFHGVREIVREQ 175 Query: 246 GLHGFYKGMGTKIVQSVFAASVLFMVKEEL 157 GL G Y+G+ +++ ++ F V L Sbjct: 176 GLKGTYQGLTATVLKQGSNQAIRFFVMTSL 205 Score = 39.3 bits (90), Expect = 0.009 Identities = 25/85 (29%), Positives = 44/85 (51%) Frame = -3 Query: 411 EVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGF 232 + L G +A +T+P VK++LQ + R+ RY G D + + +R G+ G Sbjct: 27 KAILAGGLAGGIEICITFPTEYVKTQLQLDE---RSHPPRYRGIGDCVRQTVRSHGVLGL 83 Query: 231 YKGMGTKIVQSVFAASVLFMVKEEL 157 Y+G+ + + S+ A+V F + E L Sbjct: 84 YRGLSSLLYGSIPKAAVRFGMFEFL 108
>TXTP_RAT (P32089) Tricarboxylate transport protein, mitochondrial precursor| (Citrate transport protein) (CTP) (Tricarboxylate carrier protein) (Solute carrier family 25 member 1) Length = 311 Score = 67.0 bits (162), Expect = 4e-11 Identities = 41/153 (26%), Positives = 78/153 (50%), Gaps = 1/153 (0%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGLIPTLIMV-CNPSIQFMIYETLSKRLQSKRSGKRFPKKN 424 G +RE+ RE G+ G ++GL T++ N +I+F + +L Q P K Sbjct: 163 GFFHGVREIVREQGLKGTYQGLTATVLKQGSNQAIRFFVMTSLRNWYQGDN-----PNKP 217 Query: 423 ITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEG 244 + + + GA+A + PL V+K+R+Q + A +Y TLD +++++ EG Sbjct: 218 MNPLITGVFGAVAGAASVFGNTPLDVIKTRMQGLE------AHKYRNTLDCGVQILKNEG 271 Query: 243 LHGFYKGMGTKIVQSVFAASVLFMVKEELVKFV 145 FYKG ++ + +++F++ +E+VK + Sbjct: 272 PKAFYKGTVPRLGRVCLDVAIVFVIYDEVVKLL 304 Score = 40.8 bits (94), Expect = 0.003 Identities = 33/150 (22%), Positives = 67/150 (44%), Gaps = 2/150 (1%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGLIPTLI-MVCNPSIQFMIYETLSKRLQSKRSGKRFPKKN 424 G +R+ R G+ G ++GL L + +++F ++E LS ++ + Sbjct: 66 GIGDCVRQTVRSHGVLGLYRGLSSLLYGSIPKAAVRFGMFEFLSNHMRDAQG-------R 118 Query: 423 ITAMEVFLLGAIAKLG-ATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYE 247 + + L G A + A VV P+ VK + Q ++ +Y G + +++R + Sbjct: 119 LDSRRGLLCGLGAGVAEAVVVVCPMETVKVKFIHDQT---SSNPKYRGFFHGVREIVREQ 175 Query: 246 GLHGFYKGMGTKIVQSVFAASVLFMVKEEL 157 GL G Y+G+ +++ ++ F V L Sbjct: 176 GLKGTYQGLTATVLKQGSNQAIRFFVMTSL 205 Score = 38.1 bits (87), Expect = 0.020 Identities = 25/85 (29%), Positives = 43/85 (50%) Frame = -3 Query: 411 EVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGF 232 + L G +A +T+P VK++LQ + R RY G D + + +R G+ G Sbjct: 27 KAILAGGLAGGIEICITFPTEYVKTQLQLDE---RANPPRYRGIGDCVRQTVRSHGVLGL 83 Query: 231 YKGMGTKIVQSVFAASVLFMVKEEL 157 Y+G+ + + S+ A+V F + E L Sbjct: 84 YRGLSSLLYGSIPKAAVRFGMFEFL 108
>MCAT_RAT (P97521) Mitochondrial carnitine/acylcarnitine carrier protein| (Carnitine/acylcarnitine translocase) (CAC) (Solute carrier family 25 member 20) Length = 301 Score = 66.6 bits (161), Expect = 5e-11 Identities = 45/148 (30%), Positives = 72/148 (48%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGLIPTLIMVCNPSIQFMIYETLSKRLQSKRSGKRFPKKNI 421 GTI R+ GI+G ++G+ +I V L KRLQ K P+ + Sbjct: 54 GTIDCFRKTLFREGITGLYRGMAAPIIGVTPMFAVCFFGFGLGKRLQQKS-----PEDEL 108 Query: 420 TAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGL 241 T ++F G ++ + T + P +K LQ + G+N +Y+GTLD K+ + G+ Sbjct: 109 TYPQLFTAGMLSGVFTTGIMTPGERIKCLLQIQASSGKN---KYSGTLDCAKKLYQEFGI 165 Query: 240 HGFYKGMGTKIVQSVFAASVLFMVKEEL 157 GFYKG +++ V A+ + FM E L Sbjct: 166 RGFYKGTALTLMRDVPASGMYFMTYEWL 193 Score = 51.2 bits (121), Expect = 2e-06 Identities = 42/145 (28%), Positives = 68/145 (46%), Gaps = 2/145 (1%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGLIPTLIM-VCNPSIQFMIYETLSKRLQSKRSGKRFPKKN 424 GT+ +++Y+E GI GF+KG TL+ V + FM YE L + GK + Sbjct: 151 GTLDCAKKLYQEFGIRGFYKGTALTLMRDVPASGMYFMTYEWLKNLFTPQ--GKSV--HD 206 Query: 423 ITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRY-TGTLDAILKMIRYE 247 ++ V + G + VV P V+KSR Q +Y G D + ++IR E Sbjct: 207 LSVPRVLVAGGFRGIFNWVVAIPPDVLKSRFQTAPP------GKYPNGFRDVLRELIREE 260 Query: 246 GLHGFYKGMGTKIVQSVFAASVLFM 172 G+ YKG ++++ A + F+ Sbjct: 261 GVTSLYKGFNAVMIRAFPANAACFL 285 Score = 42.4 bits (98), Expect = 0.001 Identities = 24/75 (32%), Positives = 36/75 (48%) Frame = -3 Query: 429 KNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRY 250 K I+ ++ L G + V +PL VK RLQ + Y+GT+D K + Sbjct: 6 KPISPLKNLLAGGFGGVCLVFVGHPLDTVKVRLQTQPPSLPGQPPMYSGTIDCFRKTLFR 65 Query: 249 EGLHGFYKGMGTKIV 205 EG+ G Y+GM I+ Sbjct: 66 EGITGLYRGMAAPII 80
>ADT2_YEAST (P18239) ADP,ATP carrier protein 2 (ADP/ATP translocase 2) (Adenine| nucleotide translocator 2) (ANT 2) Length = 318 Score = 62.8 bits (151), Expect = 8e-10 Identities = 38/144 (26%), Positives = 70/144 (48%), Gaps = 1/144 (0%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGLIPTLI-MVCNPSIQFMIYETLSKRLQSKRSGKRFPKKN 424 G I ++ + G++G ++G +P+++ +V + F +Y++L L + F Sbjct: 172 GLIDVYKKTLKSDGVAGLYRGFLPSVVGIVVYRGLYFGMYDSLKPLLLTGSLEGSF---- 227 Query: 423 ITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEG 244 + FLLG + GA+ +YPL V+ R+ A +Y G D + K++ EG Sbjct: 228 ---LASFLLGWVVTTGASTCSYPLDTVRRRMMMTS----GQAVKYDGAFDCLRKIVAAEG 280 Query: 243 LHGFYKGMGTKIVQSVFAASVLFM 172 + +KG G I++ V A V+ M Sbjct: 281 VGSLFKGCGANILRGVAGAGVISM 304 Score = 37.0 bits (84), Expect = 0.045 Identities = 22/95 (23%), Positives = 44/95 (46%), Gaps = 2/95 (2%) Frame = -3 Query: 435 PKKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAA--SRYTGTLDAILK 262 PKK + FL+G ++ A P+ VK +Q + E+ + +Y G LD + Sbjct: 17 PKKESNFLIDFLMGGVSAAVAKTAASPIERVKLLIQNQDEMLKQGTLDRKYAGILDCFKR 76 Query: 261 MIRYEGLHGFYKGMGTKIVQSVFAASVLFMVKEEL 157 EG+ F++G +++ ++ F K+++ Sbjct: 77 TATQEGVISFWRGNTANVIRYFPTQALNFAFKDKI 111
>ADT_KLULA (P49382) ADP,ATP carrier protein (ADP/ATP translocase) (Adenine| nucleotide translocator) (ANT) Length = 305 Score = 62.8 bits (151), Expect = 8e-10 Identities = 38/144 (26%), Positives = 68/144 (47%), Gaps = 1/144 (0%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGLIPTLI-MVCNPSIQFMIYETLSKRLQSKRSGKRFPKKN 424 G + ++ G++G ++G +P+++ +V + F +Y++L L + F Sbjct: 159 GLVDVYKKTLASDGVAGLYRGFLPSVVGIVVYRGLYFGLYDSLKPLLLTGSLENSF---- 214 Query: 423 ITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEG 244 + FLLG GA+ +YPL V+ R+ A +Y G DA K++ EG Sbjct: 215 ---LASFLLGWAVTTGASTASYPLDTVRRRMMMTS----GQAVKYDGAFDAFRKIVAAEG 267 Query: 243 LHGFYKGMGTKIVQSVFAASVLFM 172 + +KG G I++ V A V+ M Sbjct: 268 IKSLFKGCGANILRGVAGAGVISM 291 Score = 32.7 bits (73), Expect = 0.86 Identities = 18/85 (21%), Positives = 42/85 (49%), Gaps = 2/85 (2%) Frame = -3 Query: 405 FLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAA--SRYTGTLDAILKMIRYEGLHGF 232 FL+G ++ + P+ VK +Q + E+ + + RYTG ++ + EG+ F Sbjct: 14 FLMGGVSAAVSKTAAAPIERVKLLIQNQDEMIKQGSLDRRYTGIVECFKRTAADEGVASF 73 Query: 231 YKGMGTKIVQSVFAASVLFMVKEEL 157 ++G +++ ++ F K+++ Sbjct: 74 WRGNTANVIRYFPTQALNFAFKDKI 98
>MCAT_MOUSE (Q9Z2Z6) Mitochondrial carnitine/acylcarnitine carrier protein| (Carnitine/acylcarnitine translocase) (CAC) (mCAC) (Solute carrier family 25 member 20) Length = 301 Score = 62.0 bits (149), Expect = 1e-09 Identities = 42/148 (28%), Positives = 71/148 (47%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGLIPTLIMVCNPSIQFMIYETLSKRLQSKRSGKRFPKKNI 421 GT+ R+ GI+G ++G+ +I V L K+LQ K P+ + Sbjct: 54 GTLDCFRKTLMREGITGLYRGMAAPIIGVTPMFAVCFFGFGLGKKLQQKS-----PEDEL 108 Query: 420 TAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGL 241 + ++F G ++ + T + P +K LQ + G N +Y+GTLD K+ + G+ Sbjct: 109 SYPQLFTAGMLSGVFTTGIMTPGERIKCLLQIQASSGEN---KYSGTLDCAKKLYQEFGI 165 Query: 240 HGFYKGMGTKIVQSVFAASVLFMVKEEL 157 GFYKG +++ V A+ + FM E L Sbjct: 166 RGFYKGTVLTLMRDVPASGMYFMTYEWL 193 Score = 56.2 bits (134), Expect = 7e-08 Identities = 44/154 (28%), Positives = 74/154 (48%), Gaps = 2/154 (1%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGLIPTLIM-VCNPSIQFMIYETLSKRLQSKRSGKRFPKKN 424 GT+ +++Y+E GI GF+KG + TL+ V + FM YE L + GK + Sbjct: 151 GTLDCAKKLYQEFGIRGFYKGTVLTLMRDVPASGMYFMTYEWLKNLFTPE--GKSV--SD 206 Query: 423 ITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRY-TGTLDAILKMIRYE 247 ++ + + G A + V P V+KSR Q +Y G D + ++IR E Sbjct: 207 LSVPRILVAGGFAGIFNWAVAIPPDVLKSRFQTAPP------GKYPNGFRDVLRELIREE 260 Query: 246 GLHGFYKGMGTKIVQSVFAASVLFMVKEELVKFV 145 G+ YKG ++++ A + F+ E +KF+ Sbjct: 261 GVTSLYKGFNAVMIRAFPANAACFLGFEIAMKFL 294 Score = 43.9 bits (102), Expect = 4e-04 Identities = 25/75 (33%), Positives = 35/75 (46%) Frame = -3 Query: 429 KNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRY 250 K I+ + L G + V +PL VK RLQ + Y+GTLD K + Sbjct: 6 KPISPFKNLLAGGFGGMCLVFVGHPLDTVKVRLQTQPPSLSGQPPMYSGTLDCFRKTLMR 65 Query: 249 EGLHGFYKGMGTKIV 205 EG+ G Y+GM I+ Sbjct: 66 EGITGLYRGMAAPII 80
>MCATL_HUMAN (Q8N8R3) Mitchondrial carnitine/acylcarnitine carrier protein CACL| (CACT-like) (Solute carrier family 25 member 29) Length = 303 Score = 61.6 bits (148), Expect = 2e-09 Identities = 39/136 (28%), Positives = 72/136 (52%), Gaps = 2/136 (1%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGLIPTLIMVCNPS--IQFMIYETLSKRLQSKRSGKRFPKK 427 G++ + ++Y G+ G +G++ TL+ PS + F+ Y+ L++ L + P Sbjct: 133 GSLDCLAQIYGHEGLRGVNRGMVSTLLRE-TPSFGVYFLTYDALTRALGCE------PGD 185 Query: 426 NITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYE 247 + ++ L G + + + + TYP+ VVKSRLQA G A RY G LD + + R E Sbjct: 186 RLLVPKLLLAGGTSGIVSWLSTYPVDVVKSRLQAD---GLRGAPRYRGILDCVHQSYRAE 242 Query: 246 GLHGFYKGMGTKIVQS 199 G F +G+ + ++++ Sbjct: 243 GWRVFTRGLASTLLRA 258 Score = 47.8 bits (112), Expect = 3e-05 Identities = 38/150 (25%), Positives = 72/150 (48%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGLIPTLIMVCNPSIQFMIYETLSKRLQSKRSGKRFPKKNI 421 GT+ + + ++ + G +KGL L+ + I +++ L++ G P Sbjct: 41 GTLHCFKSIIKQESVLGLYKGLGSPLMGLT--FINALVFGVQGNTLRAL--GHDSP---- 92 Query: 420 TAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGL 241 + FL GA A V+ P+ + K+RLQ Q+ G A Y G+LD + ++ +EGL Sbjct: 93 --LNQFLAGAAAGAIQCVICCPMELAKTRLQL-QDAG--PARTYKGSLDCLAQIYGHEGL 147 Query: 240 HGFYKGMGTKIVQSVFAASVLFMVKEELVK 151 G +GM + +++ + V F+ + L + Sbjct: 148 RGVNRGMVSTLLRETPSFGVYFLTYDALTR 177 Score = 41.6 bits (96), Expect = 0.002 Identities = 24/80 (30%), Positives = 40/80 (50%) Frame = -3 Query: 405 FLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFYK 226 FL G + +V +P VK RLQ + +Y GTL +I+ E + G YK Sbjct: 5 FLAGCAGGVAGVLVGHPFDTVKVRLQVQSV----EKPQYRGTLHCFKSIIKQESVLGLYK 60 Query: 225 GMGTKIVQSVFAASVLFMVK 166 G+G+ ++ F +++F V+ Sbjct: 61 GLGSPLMGLTFINALVFGVQ 80
>MCAT_ARATH (Q93XM7) Mitochondrial carnitine/acylcarnitine carrier-like protein| (Protein A BOUT DE SOUFFLE) (Carnitine/acylcarnitine translocase-like protein) (CAC-like protein) Length = 300 Score = 61.6 bits (148), Expect = 2e-09 Identities = 46/148 (31%), Positives = 67/148 (45%), Gaps = 2/148 (1%) Frame = -3 Query: 600 GTIQAIREVYR-ESGISGFWKGLIPTLIM-VCNPSIQFMIYETLSKRLQSKRSGKRFPKK 427 G + R V R E G G +KGL PT V + F YE + L + Sbjct: 155 GPMDVARHVLRSEGGARGLFKGLFPTFAREVPGNATMFAAYEAFKRFLAGGSDTSSLGQG 214 Query: 426 NITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYE 247 ++ + G +A + YP VVKS LQ + RYTG++DA K+++ E Sbjct: 215 SL-----IMAGGVAGASFWGIVYPTDVVKSVLQ----VDDYKNPRYTGSMDAFRKILKSE 265 Query: 246 GLHGFYKGMGTKIVQSVFAASVLFMVKE 163 G+ G YKG G + +SV A + F+ E Sbjct: 266 GVKGLYKGFGPAMARSVPANAACFLAYE 293 Score = 50.1 bits (118), Expect = 5e-06 Identities = 25/80 (31%), Positives = 40/80 (50%) Frame = -3 Query: 396 GAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFYKGMG 217 G + VV +P +K +LQ++ RYTG +DA+ + + EG G YKGMG Sbjct: 11 GTVGGAAQLVVGHPFDTIKVKLQSQPTPAPGQLPRYTGAIDAVKQTVASEGTKGLYKGMG 70 Query: 216 TKIVQSVFAASVLFMVKEEL 157 + +VLF V+ ++ Sbjct: 71 APLATVAAFNAVLFTVRGQM 90
>ADT3_YEAST (P18238) ADP,ATP carrier protein 3 (ADP/ATP translocase 3) (Adenine| nucleotide translocator 3) (ANT 3) Length = 307 Score = 61.2 bits (147), Expect = 2e-09 Identities = 37/144 (25%), Positives = 71/144 (49%), Gaps = 1/144 (0%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGLIPTLI-MVCNPSIQFMIYETLSKRLQSKRSGKRFPKKN 424 G ++ + GI+G ++G +P+++ +V + F ++++L + + F Sbjct: 161 GLTDVYKKTLKSDGIAGLYRGFMPSVVGIVVYRGLYFGMFDSLKPLVLTGSLDGSF---- 216 Query: 423 ITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEG 244 + FLLG + GA+ +YPL V+ R+ A +Y G +D + K++ EG Sbjct: 217 ---LASFLLGWVVTTGASTCSYPLDTVRRRMMMTS----GQAVKYNGAIDCLKKIVASEG 269 Query: 243 LHGFYKGMGTKIVQSVFAASVLFM 172 + +KG G I++SV A V+ M Sbjct: 270 VGSLFKGCGANILRSVAGAGVISM 293 Score = 35.0 bits (79), Expect = 0.17 Identities = 19/85 (22%), Positives = 42/85 (49%), Gaps = 2/85 (2%) Frame = -3 Query: 405 FLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAA--SRYTGTLDAILKMIRYEGLHGF 232 FL+G ++ A P+ VK +Q + E+ + +Y+G +D + + EGL F Sbjct: 16 FLMGGVSAAIAKTAASPIERVKILIQNQDEMIKQGTLDKKYSGIVDCFKRTAKQEGLISF 75 Query: 231 YKGMGTKIVQSVFAASVLFMVKEEL 157 ++G +++ ++ F K+++ Sbjct: 76 WRGNTANVIRYFPTQALNFAFKDKI 100
>ADT1_YEAST (P04710) ADP,ATP carrier protein 1 (ADP/ATP translocase 1) (Adenine| nucleotide translocator 1) (ANT 1) Length = 309 Score = 60.8 bits (146), Expect = 3e-09 Identities = 37/153 (24%), Positives = 75/153 (49%), Gaps = 2/153 (1%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGLIPTLI-MVCNPSIQFMIYETLSKRLQSKRSGKRFPKKN 424 G + ++ + G+ G ++G +P+++ ++ + F +Y++ L + F Sbjct: 163 GLLDVYKKTLKTDGLLGLYRGFVPSVLGIIVYRGLYFGLYDSFKPVLLTGALEGSF---- 218 Query: 423 ITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEG 244 + FLLG + +GA+ +YPL V+ R+ +Y G LD + K+++ EG Sbjct: 219 ---VASFLLGWVITMGASTASYPLDTVRRRMMMTS----GQTIKYDGALDCLRKIVQKEG 271 Query: 243 LHGFYKGMGTKIVQSVFAASVLFMVKE-ELVKF 148 + +KG G I + V AA V+ + + +L+ F Sbjct: 272 AYSLFKGCGANIFRGVAAAGVISLYDQLQLIMF 304 Score = 36.2 bits (82), Expect = 0.077 Identities = 32/144 (22%), Positives = 57/144 (39%), Gaps = 2/144 (1%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGLIPTLIMVC-NPSIQFMIYETLSKRLQSKRSGKRFPKKN 424 G + + GI FW+G ++ ++ F + + L R + K Sbjct: 59 GILDCFKRTATHEGIVSFWRGNTANVLRYFPTQALNFAFKDKIKSLLSYDRERDGYAKW- 117 Query: 423 ITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASR-YTGTLDAILKMIRYE 247 A +F GA L V Y L ++RL A ++ + R + G LD K ++ + Sbjct: 118 -FAGNLFSGGAAGGLSLLFV-YSLDYARTRLAADARGSKSTSQRQFNGLLDVYKKTLKTD 175 Query: 246 GLHGFYKGMGTKIVQSVFAASVLF 175 GL G Y+G ++ + + F Sbjct: 176 GLLGLYRGFVPSVLGIIVYRGLYF 199 Score = 35.4 bits (80), Expect = 0.13 Identities = 20/85 (23%), Positives = 44/85 (51%), Gaps = 2/85 (2%) Frame = -3 Query: 405 FLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAA--SRYTGTLDAILKMIRYEGLHGF 232 FL+G ++ A P+ VK +Q ++E+ + + +RY G LD + +EG+ F Sbjct: 17 FLMGGVSAAIAKTGAAPIERVKLLMQNQEEMLKQGSLDTRYKGILDCFKRTATHEGIVSF 76 Query: 231 YKGMGTKIVQSVFAASVLFMVKEEL 157 ++G +++ ++ F K+++ Sbjct: 77 WRGNTANVLRYFPTQALNFAFKDKI 101
>DNC_MACFA (Q5IS35) Mitochondrial deoxynucleotide carrier (Solute carrier| family 25 member 19) Length = 320 Score = 60.5 bits (145), Expect = 4e-09 Identities = 43/151 (28%), Positives = 76/151 (50%), Gaps = 8/151 (5%) Frame = -3 Query: 603 YGTIQ-AIREVYRESGISGFWKGLIPTLIMVCN-PSIQFMIYETLSKRLQSKRSGKRFPK 430 Y T++ A+ +YR G F+KGL PTLI + +QF Y +L + + Sbjct: 155 YNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQFSCYSSLKHLYKWAMPAEGKKN 214 Query: 429 KNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQ------AKQEIGRNAASRYTGTLDAI 268 +N+ + L G+ A + + +TYPL + K RLQ A+ G+ RY G +D Sbjct: 215 ENLQNL---LCGSGAGVISKTLTYPLDLFKKRLQVGGFEHARAAFGQ--VRRYKGLMDCA 269 Query: 267 LKMIRYEGLHGFYKGMGTKIVQSVFAASVLF 175 ++++ EG GF+KG+ ++++ + +F Sbjct: 270 KQVLQKEGALGFFKGLSPSLLKAALSTGFMF 300 Score = 40.8 bits (94), Expect = 0.003 Identities = 27/97 (27%), Positives = 50/97 (51%), Gaps = 2/97 (2%) Frame = -3 Query: 429 KNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQE--IGRNAASRYTGTLDAILKMI 256 +N T ++V + G+++ L + P V+K R Q + E R+ ++Y G A +++ Sbjct: 11 RNNTKLQVAVAGSVSGLVTRALISPFDVIKIRFQLQHERLSRRDPNAKYHGIFQASRQIL 70 Query: 255 RYEGLHGFYKGMGTKIVQSVFAASVLFMVKEELVKFV 145 + EGL F+KG + S+ +V F+ E L + V Sbjct: 71 QEEGLTAFWKGHIPAQILSIGYGAVQFLSFEMLTELV 107
>DNC_HUMAN (Q9HC21) Mitochondrial deoxynucleotide carrier (Solute carrier| family 25 member 19) (Mitochondrial uncoupling protein 1) Length = 320 Score = 60.1 bits (144), Expect = 5e-09 Identities = 44/155 (28%), Positives = 77/155 (49%), Gaps = 8/155 (5%) Frame = -3 Query: 603 YGTIQ-AIREVYRESGISGFWKGLIPTLIMVCN-PSIQFMIYETLSKRLQSKRSGKRFPK 430 Y T++ A+ +YR G F+KGL PTLI + +QF Y +L + + Sbjct: 155 YNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQFSCYSSLKHLYKWAIPAEGKKN 214 Query: 429 KNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQ------AKQEIGRNAASRYTGTLDAI 268 +N+ + L G+ A + + +TYPL + K RLQ A+ G+ RY G +D Sbjct: 215 ENLQNL---LCGSGAGVISKTLTYPLDLFKKRLQVGGFEHARAAFGQ--VRRYKGLMDCA 269 Query: 267 LKMIRYEGLHGFYKGMGTKIVQSVFAASVLFMVKE 163 ++++ EG GF+KG+ ++++ + +F E Sbjct: 270 KQVLQKEGALGFFKGLSPSLLKAALSTGFMFFSYE 304
>TXTP_CAEEL (P34519) Putative tricarboxylate transport protein, mitochondrial| precursor (Citrate transport protein) (CTP) Length = 312 Score = 60.1 bits (144), Expect = 5e-09 Identities = 40/153 (26%), Positives = 75/153 (49%), Gaps = 1/153 (0%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGLIPTLIMV-CNPSIQFMIYETLSKRLQSKRSGKRFPKKN 424 G + + + + G+ G +KG+ T+ N +I+F + ETL R G + Sbjct: 163 GFVHGVGCIVKAEGLGGIYKGVTATMAKQGSNQAIRFFVMETLKDWY---RGGDN--TQP 217 Query: 423 ITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEG 244 I+ V L+GA+A + P+ VVK+R+Q + A +Y TLD +++ + EG Sbjct: 218 ISKPIVGLMGAVAGAASVYGNTPIDVVKTRMQGLE------AKKYKNTLDCAMQIWKKEG 271 Query: 243 LHGFYKGMGTKIVQSVFAASVLFMVKEELVKFV 145 FYKG ++ + + FM+ + +++F+ Sbjct: 272 FFAFYKGTVPRLSRVCLDVGITFMIYDSIIEFL 304 Score = 38.9 bits (89), Expect = 0.012 Identities = 36/150 (24%), Positives = 63/150 (42%), Gaps = 2/150 (1%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGLIPTLI-MVCNPSIQFMIYETLSKRLQSKRSGKRFPKKN 424 G I +++ G G ++GL L + S +F +E L + +R N Sbjct: 66 GPIDCVKQTVNGHGFFGLYRGLSVLLYGSIPKSSFRFGTFEYLKSQAADERG-------N 118 Query: 423 ITAMEVFLLGAIAKLGATVVTY-PLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYE 247 ++ + L G A L V P+ VK + Q + A +Y G + + +++ E Sbjct: 119 LSPVMRLLCGLGAGLSEAVFAVTPMETVKVKFIHDQGL---AQPKYKGFVHGVGCIVKAE 175 Query: 246 GLHGFYKGMGTKIVQSVFAASVLFMVKEEL 157 GL G YKG+ + + ++ F V E L Sbjct: 176 GLGGIYKGVTATMAKQGSNQAIRFFVMETL 205
>CMC2_CAEEL (Q20799) Probable calcium-binding mitochondrial carrier F55A11.4| Length = 588 Score = 59.7 bits (143), Expect = 7e-09 Identities = 46/156 (29%), Positives = 79/156 (50%), Gaps = 8/156 (5%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGLIPTLI-MVCNPSIQFMIYETLSKRLQSKRSGKRFPKKN 424 G I ++Y + GI F+KG +P LI ++ I IYETL KR+ R+ + N Sbjct: 383 GIIHFAHKMYTKEGIRCFYKGYLPNLIGIIPYAGIDLAIYETL------KRTYVRYYETN 436 Query: 423 ITAMEVFLLGAIAKLGAT---VVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIR 253 + V L A +T + +YP +V++RLQA + +RY+ D + + Sbjct: 437 SSEPGVLALLACGTCSSTCGQLSSYPFALVRTRLQAL------SITRYSPQPDTMFGQFK 490 Query: 252 Y----EGLHGFYKGMGTKIVQSVFAASVLFMVKEEL 157 Y EG+ GFY+G+ ++ + A S+ ++V E++ Sbjct: 491 YILQNEGVTGFYRGITPNFLKVIPAVSISYVVYEKV 526
>DNC_PONPY (Q5NVC1) Mitochondrial deoxynucleotide carrier (Solute carrier| family 25 member 19) Length = 320 Score = 59.3 bits (142), Expect = 9e-09 Identities = 43/151 (28%), Positives = 75/151 (49%), Gaps = 8/151 (5%) Frame = -3 Query: 603 YGTI-QAIREVYRESGISGFWKGLIPTLIMVCN-PSIQFMIYETLSKRLQSKRSGKRFPK 430 Y T+ A+ +YR G F+KGL PTLI + +QF Y +L + + Sbjct: 155 YNTLCHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQFSCYSSLKHLYKWAIPAEGKKN 214 Query: 429 KNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQ------AKQEIGRNAASRYTGTLDAI 268 +N+ + L G+ A + + +TYPL + K RLQ A+ G+ RY G +D Sbjct: 215 ENLQNL---LCGSGAGVISKTLTYPLDLFKKRLQVGGFEHARAAFGQ--VRRYKGLMDCA 269 Query: 267 LKMIRYEGLHGFYKGMGTKIVQSVFAASVLF 175 ++++ EG GF+KG+ ++++ + +F Sbjct: 270 KQVLQKEGALGFFKGLSPSLLKAALSTGFMF 300
>TXTP_YEAST (P38152) Tricarboxylate transport protein (Citrate transport| protein) (CTP) Length = 299 Score = 58.5 bits (140), Expect = 1e-08 Identities = 33/150 (22%), Positives = 77/150 (51%), Gaps = 1/150 (0%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGLIP-TLIMVCNPSIQFMIYETLSKRLQSKRSGKRFPKKN 424 G ++ + R+ G SG ++G++P ++ N +++ Y + +Q + K Sbjct: 154 GVVRNYSSLVRDKGFSGLYRGVLPVSMRQAANQAVRLGCYNKIKTLIQDYTDSPK--DKP 211 Query: 423 ITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEG 244 +++ FL+GA + + T PL VK+R+Q+ +++Y+ T++ + + EG Sbjct: 212 LSSGLTFLVGAFSGIVTVYSTMPLDTVKTRMQSLD------STKYSSTMNCFATIFKEEG 265 Query: 243 LHGFYKGMGTKIVQSVFAASVLFMVKEELV 154 L F+KG ++ + V + ++F + E+++ Sbjct: 266 LKTFWKGATPRLGRLVLSGGIVFTIYEKVL 295 Score = 35.8 bits (81), Expect = 0.10 Identities = 24/87 (27%), Positives = 40/87 (45%) Frame = -3 Query: 432 KKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIR 253 K ++ + FL G++A +TYP K+RLQ + + ASR L I K + Sbjct: 7 KSDVDPLHSFLAGSLAGAAEACITYPFEFAKTRLQLIDKASK--ASR--NPLVLIYKTAK 62 Query: 252 YEGLHGFYKGMGTKIVQSVFAASVLFM 172 +G+ Y G I+ + A + F+ Sbjct: 63 TQGIGSIYVGCPAFIIGNTAKAGIRFL 89
>MCATL_MOUSE (Q8BL03) Mitchondrial carnitine/acylcarnitine carrier protein CACL| (CACT-like) (Solute carrier family 25 member 29) Length = 306 Score = 58.5 bits (140), Expect = 1e-08 Identities = 35/136 (25%), Positives = 72/136 (52%), Gaps = 2/136 (1%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGLIPTLIMVCNPS--IQFMIYETLSKRLQSKRSGKRFPKK 427 G++ + ++YR G+ G +G++ TL+ PS + F+ Y+ +++ + + P Sbjct: 133 GSLDCLVQIYRHEGLRGINRGMVSTLLRE-TPSFGVYFLTYDVMTRAMGCE------PGD 185 Query: 426 NITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYE 247 + ++ L G + + + + TYP+ VVKSRLQA G RY G +D + + + E Sbjct: 186 RLLVPKLLLAGGTSGITSWLSTYPMDVVKSRLQAD---GLQGTPRYRGIVDCMRQSYQAE 242 Query: 246 GLHGFYKGMGTKIVQS 199 G F +G+ + ++++ Sbjct: 243 GWQVFTRGLASTLLRA 258 Score = 51.2 bits (121), Expect = 2e-06 Identities = 38/150 (25%), Positives = 75/150 (50%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGLIPTLIMVCNPSIQFMIYETLSKRLQSKRSGKRFPKKNI 421 GT+ + + ++ + G +KGL L+ + I +++ L++ G+ P Sbjct: 41 GTLHCFQSIIKQESVLGLYKGLGSPLMGLT--FINALVFGVQGNTLRAL--GQDSP---- 92 Query: 420 TAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGL 241 + FL GA A V+ P+ + K+RLQ Q +G A Y G+LD ++++ R+EGL Sbjct: 93 --LNQFLAGAAAGAIQCVICCPMELAKTRLQL-QAVG--PARTYKGSLDCLVQIYRHEGL 147 Query: 240 HGFYKGMGTKIVQSVFAASVLFMVKEELVK 151 G +GM + +++ + V F+ + + + Sbjct: 148 RGINRGMVSTLLRETPSFGVYFLTYDVMTR 177 Score = 44.3 bits (103), Expect = 3e-04 Identities = 24/80 (30%), Positives = 41/80 (51%) Frame = -3 Query: 405 FLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFYK 226 FL G + +V +P +VK RLQ + +Y GTL +I+ E + G YK Sbjct: 5 FLAGCAGGVAGVIVGHPFDIVKVRLQVQS----TEKPQYRGTLHCFQSIIKQESVLGLYK 60 Query: 225 GMGTKIVQSVFAASVLFMVK 166 G+G+ ++ F +++F V+ Sbjct: 61 GLGSPLMGLTFINALVFGVQ 80
>MCAT_HUMAN (O43772) Mitochondrial carnitine/acylcarnitine carrier protein| (Carnitine/acylcarnitine translocase) (CAC) (Solute carrier family 25 member 20) Length = 301 Score = 58.5 bits (140), Expect = 1e-08 Identities = 46/154 (29%), Positives = 76/154 (49%), Gaps = 2/154 (1%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGLIPTLIM-VCNPSIQFMIYETLSKRLQSKRSGKRFPKKN 424 GT+ +++Y+E GI G +KG + TL+ V + FM YE L + GKR + Sbjct: 151 GTLDCAKKLYQEFGIRGIYKGTVLTLMRDVPASGMYFMTYEWLKNIFTPE--GKRVSE-- 206 Query: 423 ITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRY-TGTLDAILKMIRYE 247 ++A + + G IA + V P V+KSR Q +Y G D + ++IR E Sbjct: 207 LSAPRILVAGGIAGIFNWAVAIPPDVLKSRFQTAPP------GKYPNGFRDVLRELIRDE 260 Query: 246 GLHGFYKGMGTKIVQSVFAASVLFMVKEELVKFV 145 G+ YKG ++++ A + F+ E +KF+ Sbjct: 261 GVTSLYKGFNAVMIRAFPANAACFLGFEVAMKFL 294 Score = 58.2 bits (139), Expect = 2e-08 Identities = 42/148 (28%), Positives = 69/148 (46%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGLIPTLIMVCNPSIQFMIYETLSKRLQSKRSGKRFPKKNI 421 GT R+ GI+G ++G+ +I V L K+LQ K P+ + Sbjct: 54 GTFDCFRKTLFREGITGLYRGMAAPIIGVTPMFAVCFFGFGLGKKLQQKH-----PEDVL 108 Query: 420 TAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGL 241 + ++F G ++ + T + P +K LQ + G S+YTGTLD K+ + G+ Sbjct: 109 SYPQLFAAGMLSGVFTTGIMTPGERIKCLLQIQASSGE---SKYTGTLDCAKKLYQEFGI 165 Query: 240 HGFYKGMGTKIVQSVFAASVLFMVKEEL 157 G YKG +++ V A+ + FM E L Sbjct: 166 RGIYKGTVLTLMRDVPASGMYFMTYEWL 193 Score = 41.6 bits (96), Expect = 0.002 Identities = 24/75 (32%), Positives = 35/75 (46%) Frame = -3 Query: 429 KNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRY 250 K I+ ++ L G + V +PL VK RLQ + Y+GT D K + Sbjct: 6 KPISPLKNLLAGGFGGVCLVFVGHPLDTVKVRLQTQPPSLPGQPPMYSGTFDCFRKTLFR 65 Query: 249 EGLHGFYKGMGTKIV 205 EG+ G Y+GM I+ Sbjct: 66 EGITGLYRGMAAPII 80
>YG2O_YEAST (P53257) Putative mitochondrial carrier YGR096W| Length = 314 Score = 58.5 bits (140), Expect = 1e-08 Identities = 41/154 (26%), Positives = 75/154 (48%), Gaps = 3/154 (1%) Frame = -3 Query: 609 RPYGT--IQAIREVYRESGISGFWKGLIP-TLIMVCNPSIQFMIYETLSKRLQSKRSGKR 439 +P+G+ ++ R + + GI FWKG IP +L+ V S QF Y ++ L Sbjct: 53 KPFGSQVMEVARSMIKNEGIRSFWKGNIPGSLLYVTYGSAQFSSYSLFNRYLT------- 105 Query: 438 FPKKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKM 259 P + ++GA A + +++V+YP V+++RL A ++ + +R + + Sbjct: 106 -PFGLEARLHSLVVGAFAGITSSIVSYPFDVLRTRLVANNQMHSMSITR------EVRDI 158 Query: 258 IRYEGLHGFYKGMGTKIVQSVFAASVLFMVKEEL 157 + EGL GF+KG + AS++F E + Sbjct: 159 WKLEGLPGFFKGSIASMTTITLTASIMFGTYETI 192 Score = 47.8 bits (112), Expect = 3e-05 Identities = 43/163 (26%), Positives = 72/163 (44%), Gaps = 3/163 (1%) Frame = -3 Query: 585 IREVYRESGISGFWKGLIPTLIMVC-NPSIQFMIYETLSKRLQSKRSGKRFPKKNITAME 409 +R++++ G+ GF+KG I ++ + SI F YET+ KK A Sbjct: 155 VRDIWKLEGLPGFFKGSIASMTTITLTASIMFGTYETIRIYCDENEKTTAAHKKWELATL 214 Query: 408 VFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFY 229 G I + A ++T+PL ++ R+Q + K R+ ++G Y Sbjct: 215 NHSAGTIGGVIAKIITFPLETIRRRMQFMNS-------------KHLEKFSRHSSVYGSY 261 Query: 228 KGMGTKIVQSVFAASVLFMVKEELVKFVI--LLVARSRTLLLT 106 KG G FA L ++K+E V + +LVA S+T+ T Sbjct: 262 KGYG-------FARIGLQILKQEGVSSLYRGILVALSKTIPTT 297 Score = 36.6 bits (83), Expect = 0.059 Identities = 21/69 (30%), Positives = 35/69 (50%) Frame = -3 Query: 429 KNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRY 250 +N+ A + L GA++ L A +T P+ +K RLQ G + ++ MI+ Sbjct: 12 QNVAAWKTLLAGAVSGLLARSITAPMDTIKIRLQLTPANGLKPFG--SQVMEVARSMIKN 69 Query: 249 EGLHGFYKG 223 EG+ F+KG Sbjct: 70 EGIRSFWKG 78
>UCP3_CANFA (Q9N2I9) Mitochondrial uncoupling protein 3 (UCP 3)| Length = 311 Score = 58.5 bits (140), Expect = 1e-08 Identities = 47/152 (30%), Positives = 68/152 (44%), Gaps = 4/152 (2%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGLIPTL----IMVCNPSIQFMIYETLSKRLQSKRSGKRFP 433 GT+ A R + RE G+ G WKG +P + I+ C + + I + K L FP Sbjct: 160 GTMDAYRTIAREEGVRGLWKGTLPNITRNAIVNCAEMVTYDIIK--EKLLDYHLLTDNFP 217 Query: 432 KKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIR 253 I+A A ATVV P+ VVK+R + +Y LD +LKM+ Sbjct: 218 CHLISAFG-------AGFCATVVASPVDVVKTRYM------NSPPGQYCSPLDCMLKMVT 264 Query: 252 YEGLHGFYKGMGTKIVQSVFAASVLFMVKEEL 157 EG FYKG ++ V+F+ E+L Sbjct: 265 QEGPTAFYKGFTPSFLRLGTWNVVMFVTYEQL 296 Score = 45.8 bits (107), Expect = 1e-04 Identities = 43/159 (27%), Positives = 72/159 (45%), Gaps = 5/159 (3%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGLIPTLIMVCN-PSIQFMIYETLSKRLQSKRSGKRFPKKN 424 G + I + R G + GL+ L + SI+ +Y+++ + K S + Sbjct: 60 GVLGTILTMVRTEGPRSPYNGLVAGLQRQMSFASIRIGLYDSVKQFYTPKGSDH----SS 115 Query: 423 ITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEG 244 IT L G A P VVK R QA +G + +Y+GT+DA + R EG Sbjct: 116 ITTR--ILAGCTTGAMAVSCAQPTDVVKVRFQASIHLGAGSNRKYSGTMDAYRTIAREEG 173 Query: 243 LHGFYKGMGTKIVQSVF---AASVLF-MVKEELVKFVIL 139 + G +KG I ++ A V + ++KE+L+ + +L Sbjct: 174 VRGLWKGTLPNITRNAIVNCAEMVTYDIIKEKLLDYHLL 212 Score = 39.7 bits (91), Expect = 0.007 Identities = 28/89 (31%), Positives = 43/89 (48%), Gaps = 3/89 (3%) Frame = -3 Query: 405 FLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASR---YTGTLDAILKMIRYEGLHG 235 FL A A ++T+PL K RLQ + E A+R Y G L IL M+R EG Sbjct: 17 FLGAGTAACFADLLTFPLDTAKVRLQIQGENQATQAARRIQYRGVLGTILTMVRTEGPRS 76 Query: 234 FYKGMGTKIVQSVFAASVLFMVKEELVKF 148 Y G+ + + + AS+ + + + +F Sbjct: 77 PYNGLVAGLQRQMSFASIRIGLYDSVKQF 105
>RIM2_YEAST (P38127) Mitochondrial carrier protein RIM2| Length = 377 Score = 58.5 bits (140), Expect = 1e-08 Identities = 41/157 (26%), Positives = 81/157 (51%), Gaps = 10/157 (6%) Frame = -3 Query: 585 IREVYRESGISGFWKGLIPTLIMVCNPSIQFMIYETLSKRLQSKRSGKRF------PKKN 424 ++ V R G +G +KGL + + +Q+++YE + KRL +RS ++F K Sbjct: 223 LKSVIRNEGFTGLYKGLSASYLGSVEGILQWLLYEQM-KRLIKERSIEKFGYQAEGTKST 281 Query: 423 ITAMEVFLL----GAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMI 256 ++ + +AK A++ TYP VV++RL +Q N +YTG + + +I Sbjct: 282 SEKVKEWCQRSGSAGLAKFVASIATYPHEVVRTRL--RQTPKENGKRKYTGLVQSFKVII 339 Query: 255 RYEGLHGFYKGMGTKIVQSVFAASVLFMVKEELVKFV 145 + EGL Y G+ ++++V + ++F E +++ + Sbjct: 340 KEEGLFSMYSGLTPHLMRTVPNSIIMFGTWEIVIRLL 376 Score = 57.4 bits (137), Expect = 3e-08 Identities = 40/135 (29%), Positives = 60/135 (44%), Gaps = 1/135 (0%) Frame = -3 Query: 597 TIQAIREVYRESGISGFWKGLIPTLIMVCNP-SIQFMIYETLSKRLQSKRSGKRFPKKNI 421 T+ I VY++ G +KGL P L+ V SI F Y T K F Sbjct: 119 TLGIIGNVYKQEGFRSLFKGLGPNLVGVIPARSINFFTYGTTKDMY-----AKAFNNGQE 173 Query: 420 TAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGL 241 T M + A A T P+ ++K+R+Q + G+ + +Y + D + +IR EG Sbjct: 174 TPMIHLMAAATAGWATATATNPIWLIKTRVQL-DKAGKTSVRQYKNSWDCLKSVIRNEGF 232 Query: 240 HGFYKGMGTKIVQSV 196 G YKG+ + SV Sbjct: 233 TGLYKGLSASYLGSV 247 Score = 33.9 bits (76), Expect = 0.38 Identities = 26/99 (26%), Positives = 42/99 (42%), Gaps = 22/99 (22%) Frame = -3 Query: 405 FLLGAIAKLGATVVTYPLLVVKSRLQA--------KQEIGRN--------------AASR 292 F+ G I + VVT P +VK+RLQ+ Q + + A + Sbjct: 56 FVAGGIGGMAGAVVTCPFDLVKTRLQSDIFLKAYKSQAVNISKGSTRPKSINYVIQAGTH 115 Query: 291 YTGTLDAILKMIRYEGLHGFYKGMGTKIVQSVFAASVLF 175 + TL I + + EG +KG+G +V + A S+ F Sbjct: 116 FKETLGIIGNVYKQEGFRSLFKGLGPNLVGVIPARSINF 154
>DNC_MOUSE (Q9DAM5) Mitochondrial deoxynucleotide carrier (Solute carrier| family 25 member 19) Length = 318 Score = 57.4 bits (137), Expect = 3e-08 Identities = 44/150 (29%), Positives = 75/150 (50%), Gaps = 11/150 (7%) Frame = -3 Query: 591 QAIREVYRESGISGFWKGLIPTLIMVCN-PSIQFMIYETLSKRLQ------SKRSGKRFP 433 +AIR +Y+ G F+KGL PT+I + +QF Y +L + K++G Sbjct: 160 EAIRTMYKTEGPFVFYKGLTPTVIAIFPYAGLQFSCYRSLKRAYDWLIPPDGKQTGNL-- 217 Query: 432 KKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQ-EIGRNAASR---YTGTLDAIL 265 KN+ L G + + + TYPL ++K RLQ E R+A + Y G LD Sbjct: 218 -KNL------LCGCGSGVISKTFTYPLDLIKKRLQVGGFEHARSAFGQVRSYRGLLDLTQ 270 Query: 264 KMIRYEGLHGFYKGMGTKIVQSVFAASVLF 175 ++++ EG GF+KG+ ++++ + +F Sbjct: 271 QVLQEEGTRGFFKGLSPSLMKAALSTGFMF 300 Score = 36.6 bits (83), Expect = 0.059 Identities = 24/92 (26%), Positives = 46/92 (50%), Gaps = 2/92 (2%) Frame = -3 Query: 414 MEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQE--IGRNAASRYTGTLDAILKMIRYEGL 241 +EV + G+++ + PL V+K R Q + E + ++Y G A ++++ EG Sbjct: 16 LEVAVAGSVSGFVTRALISPLDVIKIRFQLQIERLCPSDPNAKYHGIFQAAKQILQEEGP 75 Query: 240 HGFYKGMGTKIVQSVFAASVLFMVKEELVKFV 145 F+KG + S+ +V F+ EEL + + Sbjct: 76 RAFWKGHVPAQILSIGYGAVQFLAFEELTELL 107
>MCAT_MACFA (Q8HXY2) Mitochondrial carnitine/acylcarnitine carrier protein| (Carnitine/acylcarnitine translocase) (CAC) (Solute carrier family 25 member 20) Length = 301 Score = 56.6 bits (135), Expect = 6e-08 Identities = 40/146 (27%), Positives = 67/146 (45%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGLIPTLIMVCNPSIQFMIYETLSKRLQSKRSGKRFPKKNI 421 GT R+ GI G ++G+ +I V L K+LQ K P+ + Sbjct: 54 GTFDCFRKTLFREGIRGLYRGMAAPIIGVTPMFAVCFFGFGLGKKLQQKH-----PEDVL 108 Query: 420 TAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGL 241 + ++F G ++ + T + P +K LQ + G ++YTGTLD K+ + G+ Sbjct: 109 SYPQLFAAGMLSGIFTTGIMTPGERIKCLLQIQASSGE---TKYTGTLDCAKKLYQEFGI 165 Query: 240 HGFYKGMGTKIVQSVFAASVLFMVKE 163 G YKG +++ V A+ + FM E Sbjct: 166 RGIYKGTVVTLMRDVPASGMYFMTYE 191 Score = 53.9 bits (128), Expect = 4e-07 Identities = 44/154 (28%), Positives = 74/154 (48%), Gaps = 2/154 (1%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGLIPTLIM-VCNPSIQFMIYETLSKRLQSKRSGKRFPKKN 424 GT+ +++Y+E GI G +KG + TL+ V + FM YE + + GKR + + Sbjct: 151 GTLDCAKKLYQEFGIRGIYKGTVVTLMRDVPASGMYFMTYEWVKNIFTPE--GKRVSELS 208 Query: 423 ITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRY-TGTLDAILKMIRYE 247 + V + G IA + V P V+KSR Q +Y G D + ++I E Sbjct: 209 VP--RVLVAGGIAGIFNWAVAIPPDVLKSRFQTAPP------GKYPNGFRDVLRELIPDE 260 Query: 246 GLHGFYKGMGTKIVQSVFAASVLFMVKEELVKFV 145 G+ YKG ++++ A + F+ E +KF+ Sbjct: 261 GVTSLYKGFNAVMIRAFPANAACFLGFEVAMKFL 294 Score = 42.4 bits (98), Expect = 0.001 Identities = 24/75 (32%), Positives = 35/75 (46%) Frame = -3 Query: 429 KNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRY 250 K I+ ++ L G + V +PL VK RLQ + Y+GT D K + Sbjct: 6 KPISPLKNLLAGGFGGVCLVFVGHPLDTVKVRLQTQPPSLPGQPPMYSGTFDCFRKTLFR 65 Query: 249 EGLHGFYKGMGTKIV 205 EG+ G Y+GM I+ Sbjct: 66 EGIRGLYRGMAAPII 80
>UCP3_HUMAN (P55916) Mitochondrial uncoupling protein 3 (UCP 3)| Length = 312 Score = 56.6 bits (135), Expect = 6e-08 Identities = 45/152 (29%), Positives = 68/152 (44%), Gaps = 4/152 (2%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGLIPTL----IMVCNPSIQFMIYETLSKRLQSKRSGKRFP 433 GT+ A R + RE G+ G WKG +P + I+ C + + I + K L FP Sbjct: 161 GTMDAYRTIAREEGVRGLWKGTLPNIMRNAIVNCAEVVTYDILK--EKLLDYHLLTDNFP 218 Query: 432 KKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIR 253 ++A A ATVV P+ VVK+R + +Y LD ++KM+ Sbjct: 219 CHFVSAFG-------AGFCATVVASPVDVVKTRYM------NSPPGQYFSPLDCMIKMVA 265 Query: 252 YEGLHGFYKGMGTKIVQSVFAASVLFMVKEEL 157 EG FYKG ++ V+F+ E+L Sbjct: 266 QEGPTAFYKGFTPSFLRLGSWNVVMFVTYEQL 297 Score = 43.1 bits (100), Expect = 6e-04 Identities = 43/160 (26%), Positives = 74/160 (46%), Gaps = 6/160 (3%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGLIPTLIMVCN-PSIQFMIYETLSKRLQSKRSGKRFPKKN 424 G + I + R G + GL+ L + SI+ +Y+++ + K + N Sbjct: 60 GVLGTILTMVRTEGPCSPYNGLVAGLQRQMSFASIRIGLYDSVKQVYTPKGAD------N 113 Query: 423 ITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASR-YTGTLDAILKMIRYE 247 + L G A P VVK R QA +G + + R Y+GT+DA + R E Sbjct: 114 SSLTTRILAGCTTGAMAVTCAQPTDVVKVRFQASIHLGPSRSDRKYSGTMDAYRTIAREE 173 Query: 246 GLHGFYKGMGTKIVQS--VFAASVLF--MVKEELVKFVIL 139 G+ G +KG I+++ V A V+ ++KE+L+ + +L Sbjct: 174 GVRGLWKGTLPNIMRNAIVNCAEVVTYDILKEKLLDYHLL 213 Score = 36.6 bits (83), Expect = 0.059 Identities = 30/82 (36%), Positives = 40/82 (48%), Gaps = 4/82 (4%) Frame = -3 Query: 414 MEVFLLGA-IAKLGATVVTYPLLVVKSRLQAKQEIGRNAASR---YTGTLDAILKMIRYE 247 M V LGA A A +VT+PL K RLQ + E +R Y G L IL M+R E Sbjct: 13 MAVKFLGAGTAACFADLVTFPLDTAKVRLQIQGENQAVQTARLVQYRGVLGTILTMVRTE 72 Query: 246 GLHGFYKGMGTKIVQSVFAASV 181 G Y G+ + + + AS+ Sbjct: 73 GPCSPYNGLVAGLQRQMSFASI 94
>UCP3_PIG (O97649) Mitochondrial uncoupling protein 3 (UCP 3)| Length = 308 Score = 56.2 bits (134), Expect = 7e-08 Identities = 44/152 (28%), Positives = 68/152 (44%), Gaps = 4/152 (2%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGLIPTL----IMVCNPSIQFMIYETLSKRLQSKRSGKRFP 433 GT+ A R + RE G+ G WKG++P + I+ C + + + ++ K Sbjct: 157 GTMDAYRTIAREEGVRGLWKGILPNITRNAIVNCAEMVTYDV-------IKEKVLDYHLL 209 Query: 432 KKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIR 253 N+ V GA ATVV P+ VVK+R + +Y LD +LKM+ Sbjct: 210 TDNLPCHFVSAFGA--GFCATVVASPVDVVKTRYM------NSPPGQYQNPLDCMLKMVT 261 Query: 252 YEGLHGFYKGMGTKIVQSVFAASVLFMVKEEL 157 EG FYKG ++ V+F+ E+L Sbjct: 262 QEGPTAFYKGFTPSFLRLGSWNVVMFVSYEQL 293 Score = 45.4 bits (106), Expect = 1e-04 Identities = 42/159 (26%), Positives = 72/159 (45%), Gaps = 5/159 (3%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGLIPTLIMVCN-PSIQFMIYETLSKRLQSKRSGKRFPKKN 424 G + I + R G + GL+ L + SI+ +Y+++ + K S + Sbjct: 57 GVLGTILTMVRNEGPRSPYNGLVAGLQRQMSFASIRIGLYDSVKQLYTPKGSDH----SS 112 Query: 423 ITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEG 244 IT L G A P VVK R QA G + +Y+GT+DA + R EG Sbjct: 113 ITTR--ILAGCTTGAMAVTCAQPTDVVKVRFQASIHAGPRSNRKYSGTMDAYRTIAREEG 170 Query: 243 LHGFYKGMGTKIVQSVF---AASVLF-MVKEELVKFVIL 139 + G +KG+ I ++ A V + ++KE+++ + +L Sbjct: 171 VRGLWKGILPNITRNAIVNCAEMVTYDVIKEKVLDYHLL 209 Score = 41.2 bits (95), Expect = 0.002 Identities = 28/77 (36%), Positives = 41/77 (53%), Gaps = 1/77 (1%) Frame = -3 Query: 408 VFLLGA-IAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGF 232 V LLGA A A ++T+PL K RLQ + E +++Y G L IL M+R EG Sbjct: 15 VKLLGAGTAACFADLLTFPLDTAKVRLQIQGENQAARSAQYRGVLGTILTMVRNEGPRSP 74 Query: 231 YKGMGTKIVQSVFAASV 181 Y G+ + + + AS+ Sbjct: 75 YNGLVAGLQRQMSFASI 91
>UCP3_MOUSE (P56501) Mitochondrial uncoupling protein 3 (UCP 3)| Length = 308 Score = 56.2 bits (134), Expect = 7e-08 Identities = 51/161 (31%), Positives = 74/161 (45%), Gaps = 5/161 (3%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGLIPTL----IMVCNPSIQFMIYETLSKRLQSKRSGKRFP 433 GT+ A R + RE G+ G WKG P + I+ C + + I + K L+S FP Sbjct: 157 GTMDAYRTIAREEGVRGLWKGTWPNITRNAIVNCAEMVTYDIIK--EKLLESHLFTDNFP 214 Query: 432 KKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAA-SRYTGTLDAILKMI 256 ++A A ATVV P+ VVK+R NA RY L +LKM+ Sbjct: 215 CHFVSAFG-------AGFCATVVASPVDVVKTRYM-------NAPLGRYRSPLHCMLKMV 260 Query: 255 RYEGLHGFYKGMGTKIVQSVFAASVLFMVKEELVKFVILLV 133 EG FYKG ++ + A +V+ V E +K ++ V Sbjct: 261 AQEGPTAFYKGFVPSFLR-LGAWNVMMFVTYEQLKRALMKV 300 Score = 42.7 bits (99), Expect = 8e-04 Identities = 40/155 (25%), Positives = 69/155 (44%), Gaps = 5/155 (3%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGLIPTLIMVCN-PSIQFMIYETLSKRLQSKRSGKRFPKKN 424 G + I + R G + GL+ L + SI+ +Y+++ + K + + Sbjct: 57 GVLGTILTMVRTEGPRSPYSGLVAGLHRQMSFASIRIGLYDSVKQFYTPKGADH-----S 111 Query: 423 ITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEG 244 A+ + L G A P VVK R QA +G +Y GT+DA + R EG Sbjct: 112 SVAIRI-LAGCTTGAMAVTCAQPTDVVKVRFQAMIRLGTGGERKYRGTMDAYRTIAREEG 170 Query: 243 LHGFYKGMGTKIVQSVF---AASVLF-MVKEELVK 151 + G +KG I ++ A V + ++KE+L++ Sbjct: 171 VRGLWKGTWPNITRNAIVNCAEMVTYDIIKEKLLE 205 Score = 40.4 bits (93), Expect = 0.004 Identities = 27/91 (29%), Positives = 44/91 (48%) Frame = -3 Query: 420 TAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGL 241 T + FL A A ++T+PL K RLQ + E + +Y G L IL M+R EG Sbjct: 12 TTVVKFLGAGTAACFADLLTFPLDTAKVRLQIQGENPGAQSVQYRGVLGTILTMVRTEGP 71 Query: 240 HGFYKGMGTKIVQSVFAASVLFMVKEELVKF 148 Y G+ + + + AS+ + + + +F Sbjct: 72 RSPYSGLVAGLHRQMSFASIRIGLYDSVKQF 102
>UCP3_BOVIN (O77792) Mitochondrial uncoupling protein 3 (UCP 3)| Length = 311 Score = 56.2 bits (134), Expect = 7e-08 Identities = 43/152 (28%), Positives = 68/152 (44%), Gaps = 4/152 (2%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGLIPTL----IMVCNPSIQFMIYETLSKRLQSKRSGKRFP 433 GT+ A R + RE G+ G WKG++P + I+ C + + I + K L FP Sbjct: 160 GTMDAYRTIAREEGVRGLWKGILPNITRNAIVNCGEMVTYDIIK--EKLLDYHLLTDNFP 217 Query: 432 KKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIR 253 ++A A AT+V P+ VVK+R + +Y D +LKM+ Sbjct: 218 CHFVSAFG-------AGFCATLVASPVDVVKTRYM------NSPPGQYHSPFDCMLKMVT 264 Query: 252 YEGLHGFYKGMGTKIVQSVFAASVLFMVKEEL 157 EG FYKG ++ V+F+ E++ Sbjct: 265 QEGPTAFYKGFTPSFLRLGSWNVVMFVTYEQM 296 Score = 46.2 bits (108), Expect = 7e-05 Identities = 39/159 (24%), Positives = 68/159 (42%), Gaps = 5/159 (3%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGLIPTLIMVCN-PSIQFMIYETLSKRLQSKRSGKRFPKKN 424 G + I + R G + GL+ L + SI+ +Y+++ + K S + Sbjct: 60 GVLGTILTMVRTEGPRSLYSGLVAGLQRQMSFASIRIGLYDSVKQFYTPKGSD------H 113 Query: 423 ITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEG 244 + + L G A P VVK R QA G +Y+GT+DA + R EG Sbjct: 114 SSIITRILAGCTTGAMAVTCAQPTDVVKIRFQASMHTGLGGNRKYSGTMDAYRTIAREEG 173 Query: 243 LHGFYKGMGTKIVQSVFA----ASVLFMVKEELVKFVIL 139 + G +KG+ I ++ ++KE+L+ + +L Sbjct: 174 VRGLWKGILPNITRNAIVNCGEMVTYDIIKEKLLDYHLL 212 Score = 41.6 bits (96), Expect = 0.002 Identities = 28/89 (31%), Positives = 43/89 (48%), Gaps = 3/89 (3%) Frame = -3 Query: 405 FLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASR---YTGTLDAILKMIRYEGLHG 235 FL A A ++T+PL K RLQ + E A+R Y G L IL M+R EG Sbjct: 17 FLAAGTAACFADLLTFPLDTAKVRLQIQGENQAALAARSAQYRGVLGTILTMVRTEGPRS 76 Query: 234 FYKGMGTKIVQSVFAASVLFMVKEELVKF 148 Y G+ + + + AS+ + + + +F Sbjct: 77 LYSGLVAGLQRQMSFASIRIGLYDSVKQF 105
>MFRN1_RAT (Q66H23) Mitoferrin-1 (Mitochondrial iron transporter 1) (Solute| carrier family 25 member 37) Length = 338 Score = 55.8 bits (133), Expect = 9e-08 Identities = 39/164 (23%), Positives = 76/164 (46%), Gaps = 4/164 (2%) Frame = -3 Query: 594 IQAIREVYRESGISGFWKGLIPTLIM-VCNPSIQFMIYETLSKRLQSKRSGKRFPKKNIT 418 + IR V+R G+ F++ L M + SI F+ YE L +++ P+++ Sbjct: 182 LSCIRTVWRTEGLGAFYRSYTTQLTMNIPFQSIHFITYEFLQEQVN--------PRRDYN 233 Query: 417 AMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIG---RNAASRYTGTLDAILKMIRYE 247 + G +A A T PL V K+ L ++ + N + R +G +A + + Sbjct: 234 PQSHIISGGLAGALAAAATTPLDVCKTLLNTQENMALSLANVSGRLSGMANAFRTVYQLN 293 Query: 246 GLHGFYKGMGTKIVQSVFAASVLFMVKEELVKFVILLVARSRTL 115 GL G++KG+ +++ + + ++ + V E F+ +RTL Sbjct: 294 GLAGYFKGIQARVIYQMPSTAISWSVYEFFKYFLTKRQLENRTL 337 Score = 40.0 bits (92), Expect = 0.005 Identities = 39/153 (25%), Positives = 65/153 (42%), Gaps = 4/153 (2%) Frame = -3 Query: 603 YGTIQAIREVYRESGISGFWKGL--IPTLIMVCNPS--IQFMIYETLSKRLQSKRSGKRF 436 YG ++ I GFW+ L + ++M P+ + F YE + + L F Sbjct: 88 YGALKRIMHT------EGFWRPLRGLNVMMMGAGPAHAMYFACYENMKRTLNDV-----F 136 Query: 435 PKKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMI 256 + + + + G++A L V P VVK RLQ S++ L I + Sbjct: 137 SHQGNSHLANGIAGSMATLLHDAVMNPAEVVKQRLQMYN-------SQHQSALSCIRTVW 189 Query: 255 RYEGLHGFYKGMGTKIVQSVFAASVLFMVKEEL 157 R EGL FY+ T++ ++ S+ F+ E L Sbjct: 190 RTEGLGAFYRSYTTQLTMNIPFQSIHFITYEFL 222
>ADT_SCHPO (Q09188) ADP,ATP carrier protein (ADP/ATP translocase) (Adenine| nucleotide translocator) (ANT) Length = 322 Score = 55.8 bits (133), Expect = 9e-08 Identities = 37/142 (26%), Positives = 67/142 (47%), Gaps = 1/142 (0%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGLIPTLI-MVCNPSIQFMIYETLSKRLQSKRSGKRFPKKN 424 G + R+ YR G+ G ++G P+++ +V + F +Y+TL + F Sbjct: 177 GLVDVYRKTYRSDGLRGLYRGFGPSVVGIVVYRGLYFGMYDTLKPVVLVGPLEGNF---- 232 Query: 423 ITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEG 244 + FLLG G+ V +YPL ++ R+ + A +Y+ + + +++ EG Sbjct: 233 ---LASFLLGWAVTTGSGVASYPLDTIRRRMM----MTSGEAVKYSSSFECGRQILAKEG 285 Query: 243 LHGFYKGMGTKIVQSVFAASVL 178 F+KG G I++ V A VL Sbjct: 286 ARSFFKGAGANILRGVAGAGVL 307 Score = 38.1 bits (87), Expect = 0.020 Identities = 32/159 (20%), Positives = 61/159 (38%), Gaps = 5/159 (3%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGLIPTLIMVC-NPSIQFMIYETLSKRLQSKRSGKRFPK-- 430 G + + E G+ W+G ++ ++ F + K K+ + K Sbjct: 73 GIGECFKRTAAEEGVISLWRGNTANVLRYFPTQALNFAFKDKFKKMFGYKKERDGYAKWF 132 Query: 429 -KNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASR-YTGTLDAILKMI 256 N+ + G A + + Y L ++RL + + R + G +D K Sbjct: 133 AGNLAS------GGAAGAASLLFVYSLDYARTRLANDAKSAKKGGERQFNGLVDVYRKTY 186 Query: 255 RYEGLHGFYKGMGTKIVQSVFAASVLFMVKEELVKFVIL 139 R +GL G Y+G G +V V + F + + L V++ Sbjct: 187 RSDGLRGLYRGFGPSVVGIVVYRGLYFGMYDTLKPVVLV 225
>GHC1_PONPY (Q5RD81) Mitochondrial glutamate carrier 1 (GC-1) (Glutamate/H(+)| symporter 1) (Solute carrier family 25 member 22) Length = 323 Score = 55.5 bits (132), Expect = 1e-07 Identities = 44/124 (35%), Positives = 63/124 (50%) Frame = -3 Query: 594 IQAIREVYRESGISGFWKGLIPTLIMVCNPSIQFMIYETLSKRLQSKRSGKRFPKKNITA 415 IQ R++ R GI+G +KGL TL+ S+ +Y L L + G+ ++ Sbjct: 171 IQLTRDLLRSRGIAGLYKGLGATLLRDVPLSV---VYFPLFANLN--QLGRPASEEKSPF 225 Query: 414 MEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHG 235 FL G +A A V P VVK+RLQ+ Q G N + Y+G LD K++R+EG Sbjct: 226 YVSFLAGCVAGSAAAVAVNPCDVVKTRLQSLQR-GVNEDT-YSGILDCARKILRHEGPSA 283 Query: 234 FYKG 223 F KG Sbjct: 284 FLKG 287 Score = 41.6 bits (96), Expect = 0.002 Identities = 24/74 (32%), Positives = 35/74 (47%) Frame = -3 Query: 429 KNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRY 250 K I+ + G IA L +P+ + K+RLQ +Q N YT D ++K IR Sbjct: 4 KQISLPAKLINGGIAGLIGVTCVFPIDLAKTRLQNQQ----NGQRMYTSMSDCLIKTIRS 59 Query: 249 EGLHGFYKGMGTKI 208 EG G Y+G + Sbjct: 60 EGYFGMYRGAAVNL 73 Score = 32.0 bits (71), Expect = 1.5 Identities = 38/157 (24%), Positives = 62/157 (39%), Gaps = 25/157 (15%) Frame = -3 Query: 570 RESGISGFWKGLIPTLIMVCNPSIQFMIYETLSKRLQSKRSGKRFPKKNITAMEVFLLGA 391 R G G ++G L +V P + R Q + G++ +T ++ L G Sbjct: 58 RSEGYFGMYRGAAVNLTLV-TPEKAIKLAANDFFRHQLSKDGQK-----LTLLKEMLAGC 111 Query: 390 IAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYT----GTLDA---------------- 271 A +VT P+ ++K +LQ + GR AA R G L A Sbjct: 112 GAGTCQVIVTTPMEMLKIQLQ---DAGRIAAQRKILAAQGQLSAQGGAQPSVEAPAAPRP 168 Query: 270 -----ILKMIRYEGLHGFYKGMGTKIVQSVFAASVLF 175 ++R G+ G YKG+G +++ V + V F Sbjct: 169 TAIQLTRDLLRSRGIAGLYKGLGATLLRDVPLSVVYF 205
>AGC1_YEAST (Q12482) Mitochondrial aspartate-glutamate transporter AGC1| (Aspartate-glutamate carrier 1) Length = 902 Score = 55.1 bits (131), Expect = 2e-07 Identities = 35/128 (27%), Positives = 62/128 (48%), Gaps = 1/128 (0%) Frame = -3 Query: 579 EVYRESGISGFWKGLIPTLIM-VCNPSIQFMIYETLSKRLQSKRSGKRFPKKNITAMEVF 403 ++ ++ G+ G + G+ L+ V +I F Y L K L + + + E+ Sbjct: 672 QIVKKLGLRGLYNGVAACLMRDVPFSAIYFPTYAHLKKDLFDFDPNDKTKRNRLKTWELL 731 Query: 402 LLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFYKG 223 GAIA + A +T P V+K+RLQ R ++Y G AI +++ E F+KG Sbjct: 732 TAGAIAGMPAAFLTTPFDVIKTRLQIDP---RKGETKYNGIFHAIRTILKEESFRSFFKG 788 Query: 222 MGTKIVQS 199 G ++++S Sbjct: 789 GGARVLRS 796 Score = 50.8 bits (120), Expect = 3e-06 Identities = 27/68 (39%), Positives = 47/68 (69%), Gaps = 1/68 (1%) Frame = -3 Query: 405 FLLGAIAK-LGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFY 229 F LG+IA +GATVV YP+ +K+R+QA++ + ++Y ++D +LK+I EG+ G Y Sbjct: 534 FSLGSIAGCIGATVV-YPIDFIKTRMQAQRSL-----AQYKNSIDCLLKIISREGIKGLY 587 Query: 228 KGMGTKIV 205 G+G +++ Sbjct: 588 SGLGPQLI 595 Score = 46.2 bits (108), Expect = 7e-05 Identities = 39/150 (26%), Positives = 67/150 (44%), Gaps = 1/150 (0%) Frame = -3 Query: 597 TIQAIREVYRESGISGFWKGLIPTLIMVC-NPSIQFMIYETLSKRLQSKRSGKRFPKKNI 421 +I + ++ GI G + GL P LI V +I+ + + + RL K +GK + Sbjct: 570 SIDCLLKIISREGIKGLYSGLGPQLIGVAPEKAIKLTVNDFMRNRLTDK-NGK------L 622 Query: 420 TAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGL 241 + + GA A + T PL +VK RLQ + + + T I+K + GL Sbjct: 623 SLFPEIISGASAGACQVIFTNPLEIVKIRLQVQSDYVGENIQQANETATQIVKKL---GL 679 Query: 240 HGFYKGMGTKIVQSVFAASVLFMVKEELVK 151 G Y G+ +++ V +++ F L K Sbjct: 680 RGLYNGVAACLMRDVPFSAIYFPTYAHLKK 709
>AGC1_ASHGO (Q75AH6) Mitochondrial aspartate-glutamate transporter AGC1| (Aspartate-glutamate carrier 1) Length = 911 Score = 54.7 bits (130), Expect = 2e-07 Identities = 29/109 (26%), Positives = 65/109 (59%), Gaps = 2/109 (1%) Frame = -3 Query: 525 LIMVCNPS-IQFMIYETLSKRLQSK-RSGKRFPKKNITAMEVFLLGAIAKLGATVVTYPL 352 ++ + NP+ + +++ +R++S+ RS + ++ F LG++A +V YP+ Sbjct: 485 IMKIVNPNYLNDLVHHMELRRIESESRSSNLYFYPIFDSIYNFTLGSVAGCIGAMVVYPI 544 Query: 351 LVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFYKGMGTKIV 205 +VK+R+QA+++ S+Y ++D +LK++ EG+ G Y G+G +++ Sbjct: 545 DMVKTRMQAQRDF-----SKYKNSIDCLLKILSKEGVRGLYSGLGPQLI 588 Score = 46.2 bits (108), Expect = 7e-05 Identities = 36/142 (25%), Positives = 64/142 (45%), Gaps = 1/142 (0%) Frame = -3 Query: 597 TIQAIREVYRESGISGFWKGLIPTLIMVC-NPSIQFMIYETLSKRLQSKRSGKRFPKKNI 421 +I + ++ + G+ G + GL P LI V +I+ + + + L + P + I Sbjct: 563 SIDCLLKILSKEGVRGLYSGLGPQLIGVAPEKAIKLTVNDHMRATLAGRDGKLSLPCEII 622 Query: 420 TAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGL 241 + GA A V T PL +VK RLQ K + +AA + I + GL Sbjct: 623 S-------GATAGACQVVFTNPLEIVKIRLQVKSDYVADAARNSVNAISVIKNL----GL 671 Query: 240 HGFYKGMGTKIVQSVFAASVLF 175 G Y+G G +++ + +++ F Sbjct: 672 IGLYRGAGACLLRDIPFSAIYF 693 Score = 44.3 bits (103), Expect = 3e-04 Identities = 33/130 (25%), Positives = 62/130 (47%), Gaps = 4/130 (3%) Frame = -3 Query: 576 VYRESGISGFWKGLIPTLIM-VCNPSIQFMIYETLSKRL---QSKRSGKRFPKKNITAME 409 V + G+ G ++G L+ + +I F Y + + K S KR + + Sbjct: 665 VIKNLGLIGLYRGAGACLLRDIPFSAIYFPTYAHIKSNVFNFDPKDSDKR---NKLNTWQ 721 Query: 408 VFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFY 229 + + G +A + A +T P V+K+RLQ + G + Y G DA +++ EG+ F+ Sbjct: 722 LLVSGGLAGMPAAFLTTPFDVIKTRLQIDPKKGESV---YNGIWDAARTILKEEGIKSFF 778 Query: 228 KGMGTKIVQS 199 KG ++++S Sbjct: 779 KGGPARVLRS 788
>GHC1_HUMAN (Q9H936) Mitochondrial glutamate carrier 1 (GC-1) (Glutamate/H(+)| symporter 1) (Solute carrier family 25 member 22) Length = 323 Score = 54.7 bits (130), Expect = 2e-07 Identities = 46/129 (35%), Positives = 65/129 (50%) Frame = -3 Query: 609 RPYGTIQAIREVYRESGISGFWKGLIPTLIMVCNPSIQFMIYETLSKRLQSKRSGKRFPK 430 RP T Q R++ R GI+G +KGL TL+ S+ +Y L L + G+ + Sbjct: 167 RPTAT-QLTRDLLRSRGIAGLYKGLGATLLRDVPFSV---VYFPLFANLN--QLGRPASE 220 Query: 429 KNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRY 250 + FL G +A A V P VVK+RLQ+ Q G N + Y+G LD K++R+ Sbjct: 221 EKSPFYVSFLAGCVAGSAAAVAVNPCDVVKTRLQSLQR-GVNEDT-YSGILDCARKILRH 278 Query: 249 EGLHGFYKG 223 EG F KG Sbjct: 279 EGPSAFLKG 287 Score = 40.4 bits (93), Expect = 0.004 Identities = 23/74 (31%), Positives = 35/74 (47%) Frame = -3 Query: 429 KNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRY 250 K I+ + G IA L +P+ + K+RLQ +Q N YT D ++K +R Sbjct: 4 KQISLPAKLINGGIAGLIGVTCVFPIDLAKTRLQNQQ----NGQRVYTSMSDCLIKTVRS 59 Query: 249 EGLHGFYKGMGTKI 208 EG G Y+G + Sbjct: 60 EGYFGMYRGAAVNL 73 Score = 32.7 bits (73), Expect = 0.86 Identities = 36/155 (23%), Positives = 61/155 (39%), Gaps = 23/155 (14%) Frame = -3 Query: 570 RESGISGFWKGLIPTLIMVCNPSIQFMIYETLSKRLQSKRSGKRFPKKNITAMEVFLLGA 391 R G G ++G L +V P + R Q + G++ +T ++ L G Sbjct: 58 RSEGYFGMYRGAAVNLTLV-TPEKAIKLAANDFFRHQLSKDGQK-----LTLLKEMLAGC 111 Query: 390 IAKLGATVVTYPLLVVKSRLQ-----------------------AKQEIGRNAASRYTGT 280 A +VT P+ ++K +LQ A+ + AA R T T Sbjct: 112 GAGTCQVIVTTPMEMLKIQLQDAGRIAAQRKILAAQGQLSAQGGAQPSVEAPAAPRPTAT 171 Query: 279 LDAILKMIRYEGLHGFYKGMGTKIVQSVFAASVLF 175 ++R G+ G YKG+G +++ V + V F Sbjct: 172 -QLTRDLLRSRGIAGLYKGLGATLLRDVPFSVVYF 205
>CMC1_YEAST (P48233) Calcium-binding mitochondrial carrier SAL1 (Suppressor of| AAC2 lethality) Length = 545 Score = 54.3 bits (129), Expect = 3e-07 Identities = 38/155 (24%), Positives = 76/155 (49%), Gaps = 4/155 (2%) Frame = -3 Query: 591 QAIREVYRESGISGFWKGLIPTLIMVCN-PSIQFMIYETLSKRLQSKRSGK-RFPKKNIT 418 Q ++++RE G+ F++G+ ++ + ++ + L K +K++ P+ +T Sbjct: 392 QTAKDMFREGGLRLFYRGVTVGIVGIFPYAALDLGTFSALKKWYIAKQAKTLNLPQDQVT 451 Query: 417 AMEVFLL--GAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEG 244 + +L GA + V YP+ ++++RLQA+ Y G D +LK + EG Sbjct: 452 LSNLVVLPMGAFSGTVGASVVYPINLLRTRLQAQGTYAHPYV--YNGFKDVLLKTLEREG 509 Query: 243 LHGFYKGMGTKIVQSVFAASVLFMVKEELVKFVIL 139 G +KG+ + + A S+ ++ E L KF+ L Sbjct: 510 YQGLFKGLVPTLAKVCPAVSISYLCYENLKKFMNL 544 Score = 33.9 bits (76), Expect = 0.38 Identities = 17/45 (37%), Positives = 23/45 (51%), Gaps = 1/45 (2%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGLIPTLIMVCNP-SIQFMIYETLSK 469 G + + G G +KGL+PTL VC SI ++ YE L K Sbjct: 496 GFKDVLLKTLEREGYQGLFKGLVPTLAKVCPAVSISYLCYENLKK 540
>SFC1_YEAST (P33303) Succinate/fumarate mitochondrial transporter (Regulator of| acetyl-CoA synthetase activity) Length = 322 Score = 53.9 bits (128), Expect = 4e-07 Identities = 43/159 (27%), Positives = 74/159 (46%), Gaps = 4/159 (2%) Frame = -3 Query: 609 RPYGTIQAIREVYRESGISGFWKGLIPTLI-MVCNPSIQFMIYETLSKRLQSKRSGKRFP 433 +P G I+ R +Y++ G +KGL +I ++ +I+F YE L +K SG Sbjct: 51 KPPGFIKTGRTIYQKEGFLALYKGLGAVVIGIIPKMAIRFSSYEFYRTLLVNKESGI--- 107 Query: 432 KKNITAMEVFLLGAIAKLG-ATVVTYPLLVVKSRLQAKQEIGR--NAASRYTGTLDAILK 262 ++ F+ G A + A +V P+ VVK RLQA+ NA +Y + A Sbjct: 108 ---VSTGNTFVAGVGAGITEAVLVVNPMEVVKIRLQAQHLTPSEPNAGPKYNNAIHAAYT 164 Query: 261 MIRYEGLHGFYKGMGTKIVQSVFAASVLFMVKEELVKFV 145 +++ EG+ Y+G+ + F V +L +F+ Sbjct: 165 IVKEEGVSALYRGVSLTAARQATNQGANFTVYSKLKEFL 203 Score = 44.7 bits (104), Expect = 2e-04 Identities = 34/145 (23%), Positives = 60/145 (41%), Gaps = 1/145 (0%) Frame = -3 Query: 594 IQAIREVYRESGISGFWKGLIPTLI-MVCNPSIQFMIYETLSKRLQSKRSGKRFPKKNIT 418 I A + +E G+S ++G+ T N F +Y L + LQ+ P Sbjct: 159 IHAAYTIVKEEGVSALYRGVSLTAARQATNQGANFTVYSKLKEFLQNYHQMDVLP----- 213 Query: 417 AMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLH 238 + E +G I+ PL +K+RLQ + I S + ++++ EG Sbjct: 214 SWETSCIGLISGAIGPFSNAPLDTIKTRLQKDKSISLEKQSGMKKIITIGAQLLKEEGFR 273 Query: 237 GFYKGMGTKIVQSVFAASVLFMVKE 163 YKG+ ++++ +V F V E Sbjct: 274 ALYKGITPRVMRVAPGQAVTFTVYE 298
>UCP3_RAT (P56499) Mitochondrial uncoupling protein 3 (UCP 3)| Length = 308 Score = 53.5 bits (127), Expect = 5e-07 Identities = 47/153 (30%), Positives = 68/153 (44%), Gaps = 5/153 (3%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGLIPTL----IMVCNPSIQFMIYETLSKRLQSKRSGKRFP 433 GT+ A R + RE G+ G WKG P + I+ C + + I + K L S FP Sbjct: 157 GTMDAYRTIAREEGVRGLWKGTWPNITRNAIVNCAEMVTYDIIK--EKLLDSHLFTDNFP 214 Query: 432 KKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAA-SRYTGTLDAILKMI 256 ++A A ATVV P+ VVK+R NA RY L +L+M+ Sbjct: 215 CHFVSAFG-------AGFCATVVASPVDVVKTRYM-------NAPPGRYRSPLHCMLRMV 260 Query: 255 RYEGLHGFYKGMGTKIVQSVFAASVLFMVKEEL 157 EG FYKG ++ ++F+ E+L Sbjct: 261 AQEGPTAFYKGFMPSFLRLGSWNVMMFVTYEQL 293 Score = 42.7 bits (99), Expect = 8e-04 Identities = 39/155 (25%), Positives = 67/155 (43%), Gaps = 1/155 (0%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGLIPTLIMVCN-PSIQFMIYETLSKRLQSKRSGKRFPKKN 424 G + I + R G + GL+ L + SI+ +Y+++ + K + + Sbjct: 57 GVLGTILTMVRTEGPRSPYSGLVAGLHRQMSFASIRIGLYDSVKQFYTPKGTDH-----S 111 Query: 423 ITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEG 244 A+ + L G A P VVK R QA +G +Y GT+DA + R EG Sbjct: 112 SVAIRI-LAGCTTGAMAVTCAQPTDVVKVRFQAMIRLGTGGERKYRGTMDAYRTIAREEG 170 Query: 243 LHGFYKGMGTKIVQSVFAASVLFMVKEELVKFVIL 139 + G +KG I ++ + MV +++K +L Sbjct: 171 VRGLWKGTWPNITRNAI-VNCAEMVTYDIIKEKLL 204 Score = 40.0 bits (92), Expect = 0.005 Identities = 27/91 (29%), Positives = 44/91 (48%) Frame = -3 Query: 420 TAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGL 241 T + FL A A ++T+PL K RLQ + E + +Y G L IL M+R EG Sbjct: 12 TTVVKFLGAGTAACFADLLTFPLDTAKVRLQIQGENPGVQSVQYRGVLGTILTMVRTEGP 71 Query: 240 HGFYKGMGTKIVQSVFAASVLFMVKEELVKF 148 Y G+ + + + AS+ + + + +F Sbjct: 72 RSPYSGLVAGLHRQMSFASIRIGLYDSVKQF 102
>COLT_DROME (Q9VQG4) Congested-like trachea protein| Length = 306 Score = 53.1 bits (126), Expect = 6e-07 Identities = 37/148 (25%), Positives = 67/148 (45%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGLIPTLIMVCNPSIQFMIYETLSKRLQSKRSGKRFPKKNI 421 GT + + G+ G +KG+ L V L KRLQ + + + Sbjct: 59 GTFDCAAKTIKNEGVRGLYKGMSAPLTGVAPIFAMCFAGYALGKRLQQRGEDAK-----L 113 Query: 420 TAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGL 241 T ++F+ G+ + L +T++ P +K LQ +Q G+ +Y G +D K+ + GL Sbjct: 114 TYPQIFVAGSFSGLFSTLIMAPGERIKVLLQTQQ--GQGGERKYNGMIDCAGKLYKEGGL 171 Query: 240 HGFYKGMGTKIVQSVFAASVLFMVKEEL 157 +KG +++ + A + F+V E L Sbjct: 172 RSVFKGSCATMLRDLPANGLYFLVYEAL 199 Score = 42.4 bits (98), Expect = 0.001 Identities = 25/83 (30%), Positives = 37/83 (44%), Gaps = 2/83 (2%) Frame = -3 Query: 432 KKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIR 253 ++ ++ FL G + + +PL +K RLQ Y GT D K I+ Sbjct: 10 ERKANPVKSFLTGGFGGICNVLSGHPLDTIKVRLQTMPRPAPGEQPLYRGTFDCAAKTIK 69 Query: 252 YEGLHGFYKGMGTKI--VQSVFA 190 EG+ G YKGM + V +FA Sbjct: 70 NEGVRGLYKGMSAPLTGVAPIFA 92
>ARG13_NEUCR (Q01356) Amino acid transporter arg-13| Length = 363 Score = 53.1 bits (126), Expect = 6e-07 Identities = 46/172 (26%), Positives = 77/172 (44%), Gaps = 23/172 (13%) Frame = -3 Query: 594 IQAIREVYRESGISGFWKGLIPTLIMVCNP-SIQFMIYETLSKRLQSKRSGKRFPKKNIT 418 I I+E++R G+ GFW G + TLI + F ET SK + R+ + K+ + Sbjct: 190 IPVIKEIFRHEGLRGFWHGQLGTLIREAGGCAAWFGSKETTSKWFRG-RNERALLKRGAS 248 Query: 417 AMEVF-------------LLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTL 277 EV + GA A + + +P VKSR+Q IG + G Sbjct: 249 QEEVVASRERPLPLWQQAIAGASAGMSYNFLFFPADTVKSRMQT-SPIGGGGDNGGKGAA 307 Query: 276 DAILK---------MIRYEGLHGFYKGMGTKIVQSVFAASVLFMVKEELVKF 148 + K + + G+ GFY+G G +++S +++ +FMV + L K+ Sbjct: 308 TMMPKKSFGEEARALWKQAGIKGFYRGCGITVLRSAPSSAFIFMVYDGLKKY 359 Score = 46.6 bits (109), Expect = 6e-05 Identities = 27/81 (33%), Positives = 42/81 (51%) Frame = -3 Query: 417 AMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLH 238 A+E + G+ A + + YP VK RLQ++ + + RYTG LD + IR +G Sbjct: 42 ALEDIVYGSAAGIVGKYIEYPFDTVKVRLQSQPD---HLPLRYTGPLDCFRQSIRADGFL 98 Query: 237 GFYKGMGTKIVQSVFAASVLF 175 G Y+G+ +V + S LF Sbjct: 99 GLYRGISAPLVGAALENSSLF 119 Score = 45.8 bits (107), Expect = 1e-04 Identities = 32/152 (21%), Positives = 64/152 (42%), Gaps = 1/152 (0%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGLIPTLIMVCNPSIQFMIYETLSKRLQSKRSGKRFPKKNI 421 G + R+ R G G ++G+ L+ + +E + + L SG + Sbjct: 83 GPLDCFRQSIRADGFLGLYRGISAPLVGAALENSSLFFFERIGRSLLYS-SGFAPRDSEL 141 Query: 420 TAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIG-RNAASRYTGTLDAILKMIRYEG 244 + ++ G + +++ P+ +VK ++Q E G A R + I ++ R+EG Sbjct: 142 SLSALWFTGGFSGAFTSLILTPVELVKCKIQVPDEPGGAGARQRQLKPIPVIKEIFRHEG 201 Query: 243 LHGFYKGMGTKIVQSVFAASVLFMVKEELVKF 148 L GF+ G +++ + F KE K+ Sbjct: 202 LRGFWHGQLGTLIREAGGCAAWFGSKETTSKW 233
>MFRN1_MOUSE (Q920G8) Mitoferrin-1 (Mitochondrial iron transporter 1) (Solute| carrier family 25 member 37) (Mitochondria solute carrier protein) Length = 338 Score = 52.8 bits (125), Expect = 8e-07 Identities = 38/161 (23%), Positives = 74/161 (45%), Gaps = 4/161 (2%) Frame = -3 Query: 585 IREVYRESGISGFWKGLIPTLIM-VCNPSIQFMIYETLSKRLQSKRSGKRFPKKNITAME 409 IR V+R G+ F++ L M + SI F+ YE L +++ P+++ Sbjct: 185 IRTVWRTEGLGAFYRSYTTQLTMNIPFQSIHFITYEFLQEQVN--------PRRDYNPQS 236 Query: 408 VFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIG---RNAASRYTGTLDAILKMIRYEGLH 238 + G +A A T PL V K+ L ++ + N + R +G +A + + GL Sbjct: 237 HIISGGLAGALAAAATTPLDVCKTLLNTQENMALSLANVSGRLSGMANAFRTVYQLNGLA 296 Query: 237 GFYKGMGTKIVQSVFAASVLFMVKEELVKFVILLVARSRTL 115 G++KG+ +++ + + ++ + V E + +RTL Sbjct: 297 GYFKGIQARVIYQMPSTAISWSVYEFFKYILTKRQLENRTL 337 Score = 38.1 bits (87), Expect = 0.020 Identities = 38/153 (24%), Positives = 64/153 (41%), Gaps = 4/153 (2%) Frame = -3 Query: 603 YGTIQAIREVYRESGISGFWKGL--IPTLIMVCNPS--IQFMIYETLSKRLQSKRSGKRF 436 YG ++ I GFW+ L + ++M P+ + F YE + + L F Sbjct: 88 YGALKRIMHT------EGFWRPLRGLNVMMMGAGPAHAMYFACYENMKRTLNDV-----F 136 Query: 435 PKKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMI 256 + + + + G++A L V P VVK RLQ S++ I + Sbjct: 137 SHQGNSHLANGVAGSMATLLHDAVMNPAEVVKQRLQMYN-------SQHQSAFSCIRTVW 189 Query: 255 RYEGLHGFYKGMGTKIVQSVFAASVLFMVKEEL 157 R EGL FY+ T++ ++ S+ F+ E L Sbjct: 190 RTEGLGAFYRSYTTQLTMNIPFQSIHFITYEFL 222
>UCP5_MOUSE (Q9Z2B2) Brain mitochondrial carrier protein 1 (BMCP-1)| (Mitochondrial uncoupling protein 5) (UCP 5) (Solute carrier family 25 member 14) Length = 325 Score = 52.4 bits (124), Expect = 1e-06 Identities = 41/151 (27%), Positives = 73/151 (48%), Gaps = 5/151 (3%) Frame = -3 Query: 579 EVYRESGISGFWKGLIPTL----IMVCNPSIQFMIYETLSKRL-QSKRSGKRFPKKNITA 415 ++Y++ G G W+G++PT I+V ++ +Y+ K L S G +++ Sbjct: 186 DIYQQEGTRGLWRGVVPTAQRAAIVV---GVELPVYDITKKHLIVSGMLGDTILTHFVSS 242 Query: 414 MEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHG 235 L GA+A + P+ VV++R+ ++ I + Y GTLD ILKM ++EG Sbjct: 243 FTCGLAGALA-------SNPVDVVRTRMMNQRAIVGHV-DLYKGTLDGILKMWKHEGFFA 294 Query: 234 FYKGMGTKIVQSVFAASVLFMVKEELVKFVI 142 YKG ++ + F+ E+L + I Sbjct: 295 LYKGFWPNWLRLGPWNIIFFITYEQLKRLQI 325 Score = 36.2 bits (82), Expect = 0.077 Identities = 21/90 (23%), Positives = 45/90 (50%), Gaps = 2/90 (2%) Frame = -3 Query: 405 FLLGAIAKLGATVVTYPLLVVKSRLQAK-QEIG-RNAASRYTGTLDAILKMIRYEGLHGF 232 F+ G +A + A T+P+ + K+RLQ + Q I R +Y G A+ ++ + EG+ Sbjct: 44 FVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDVRFKEIKYRGMFHALFRIYKEEGILAL 103 Query: 231 YKGMGTKIVQSVFAASVLFMVKEELVKFVI 142 Y G+ +++ ++ + + L + + Sbjct: 104 YSGIAPALLRQASYGTIKIGIYQSLKRLFV 133
>ADT1_GOSHI (O22342) ADP,ATP carrier protein 1, mitochondrial precursor| (ADP/ATP translocase 1) (Adenine nucleotide translocator 1) (ANT 1) Length = 386 Score = 52.4 bits (124), Expect = 1e-06 Identities = 35/142 (24%), Positives = 68/142 (47%), Gaps = 1/142 (0%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGL-IPTLIMVCNPSIQFMIYETLSKRLQSKRSGKRFPKKN 424 G + R+ + GI+G ++G I + ++ + F +Y++L L + F Sbjct: 236 GLVDVYRKTLKSDGIAGLYRGFNISCVGIIVYRGLYFGMYDSLKPVLLTGSMQDSF---- 291 Query: 423 ITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEG 244 F+LG + GA + +YP+ V+ R+ A +Y +LDA ++++ EG Sbjct: 292 ---FASFVLGWLITNGAALASYPIDTVRRRMMMTS----GKAVKYKSSLDAFSQILKNEG 344 Query: 243 LHGFYKGMGTKIVQSVFAASVL 178 +KG G+ I++++ A VL Sbjct: 345 GKSLFKGAGSNILRAIAGAGVL 366
>YFL5_YEAST (P43617) Putative mitochondrial carrier YFR045W| Length = 285 Score = 52.0 bits (123), Expect = 1e-06 Identities = 37/147 (25%), Positives = 70/147 (47%), Gaps = 1/147 (0%) Frame = -3 Query: 594 IQAIREVYRESGISGFWKGLIPTLI-MVCNPSIQFMIYETLSKRLQSKRSGKRFPKKNIT 418 + A++ +Y+ G + F +G T+ + N SIQF Y + LQ++ N Sbjct: 144 LPAVKHMYQTRGPAAFVQGTTATIFRQIANTSIQFTAYTAFKRLLQAR---------NDK 194 Query: 417 AMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLH 238 A V + G +T P+ VVK+R+ ++ NA + Y TL+ + ++ EG+ Sbjct: 195 ASSV-ITGLATSFTLVAMTQPIDVVKTRMMSQ-----NAKTEYKNTLNCMYRIFVQEGMA 248 Query: 237 GFYKGMGTKIVQSVFAASVLFMVKEEL 157 F+KG + ++ + + F V E++ Sbjct: 249 TFWKGSIFRFMKVGISGGLTFTVYEQV 275
>DIF1_CAEEL (Q27257) Protein dif-1| Length = 312 Score = 52.0 bits (123), Expect = 1e-06 Identities = 36/150 (24%), Positives = 65/150 (43%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGLIPTLIMVCNPSIQFMIYETLSKRLQSKRSGKRFPKKNI 421 G + ++ + G +KG+ L+ V F + K LQ P + + Sbjct: 48 GALDCVKRTVSKEGFFALYKGMAAPLVGVSPLFAVFFGGCAVGKWLQQTD-----PSQEM 102 Query: 420 TAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGL 241 T ++ GA+A + T+V P +K LQ +Q + Y G LD + K+ + G+ Sbjct: 103 TFIQNANAGALAGVFTTIVMVPGERIKCLLQVQQAGSAGSGVHYDGPLDVVKKLYKQGGI 162 Query: 240 HGFYKGMGTKIVQSVFAASVLFMVKEELVK 151 Y+G G +++ + A++ V E L K Sbjct: 163 SSIYRGTGATLLRDIPASAAYLSVYEYLKK 192 Score = 38.9 bits (89), Expect = 0.012 Identities = 19/67 (28%), Positives = 30/67 (44%) Frame = -3 Query: 405 FLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFYK 226 F+ G + +V +P VK R+Q ++TG LD + + + EG YK Sbjct: 8 FIAGGVGGSCTVIVGHPFDTVKVRIQTMPMPKPGEKPQFTGALDCVKRTVSKEGFFALYK 67 Query: 225 GMGTKIV 205 GM +V Sbjct: 68 GMAAPLV 74
>UCP5_HUMAN (O95258) Brain mitochondrial carrier protein 1 (BMCP-1)| (Mitochondrial uncoupling protein 5) (UCP 5) (Solute carrier family 25 member 14) Length = 325 Score = 51.6 bits (122), Expect = 2e-06 Identities = 40/151 (26%), Positives = 73/151 (48%), Gaps = 5/151 (3%) Frame = -3 Query: 579 EVYRESGISGFWKGLIPTL----IMVCNPSIQFMIYETLSKRL-QSKRSGKRFPKKNITA 415 ++Y++ G G W+G++PT I+V ++ +Y+ K L S G +++ Sbjct: 186 DIYQQEGTRGLWRGVVPTAQRAAIVV---GVELPVYDITKKHLILSGMMGDTILTHFVSS 242 Query: 414 MEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHG 235 L GA+A + P+ VV++R+ ++ I + Y GT+D ILKM ++EG Sbjct: 243 FTCGLAGALA-------SNPVDVVRTRMMNQRAIVGHV-DLYKGTVDGILKMWKHEGFFA 294 Query: 234 FYKGMGTKIVQSVFAASVLFMVKEELVKFVI 142 YKG ++ + F+ E+L + I Sbjct: 295 LYKGFWPNWLRLGPWNIIFFITYEQLKRLQI 325 Score = 36.2 bits (82), Expect = 0.077 Identities = 19/90 (21%), Positives = 44/90 (48%), Gaps = 2/90 (2%) Frame = -3 Query: 405 FLLGAIAKLGATVVTYPLLVVKSRLQAKQEI--GRNAASRYTGTLDAILKMIRYEGLHGF 232 F+ G +A + A T+P+ + K+RLQ + + R +Y G A+ ++ + EG+ Sbjct: 44 FVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGVLAL 103 Query: 231 YKGMGTKIVQSVFAASVLFMVKEELVKFVI 142 Y G+ +++ ++ + + L + + Sbjct: 104 YSGIAPALLRQASYGTIKIGIYQSLKRLFV 133
>ORT1_YEAST (Q12375) Mitochondrial ornithine carrier protein| Length = 292 Score = 51.6 bits (122), Expect = 2e-06 Identities = 38/147 (25%), Positives = 63/147 (42%), Gaps = 1/147 (0%) Frame = -3 Query: 594 IQAIREVYRESGISGFWKGLIPTLIMVCNPSIQ-FMIYETLSKRLQSKRSGKRFPKKNIT 418 + I+ + E G++G W+G T I + F YE + K L+ + S + Sbjct: 153 LPTIKAIITERGLAGLWQGQSGTFIRESFGGVAWFATYEIVKKSLKDRHSLDDPKRDESK 212 Query: 417 AMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLH 238 E+ + G A L +P VKS +Q + NA + G GL Sbjct: 213 IWELLISGGSAGLAFNASIFPADTVKSVMQTEHISLTNAVKKIFGKF----------GLK 262 Query: 237 GFYKGMGTKIVQSVFAASVLFMVKEEL 157 GFY+G+G + ++V A + +F + E L Sbjct: 263 GFYRGLGITLFRAVPANAAVFYIFETL 289 Score = 32.0 bits (71), Expect = 1.5 Identities = 23/85 (27%), Positives = 42/85 (49%), Gaps = 1/85 (1%) Frame = -3 Query: 396 GAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGL-HGFYKGM 220 G+IA V+ +P VK RLQ + A++ + T I + EG+ GF++G+ Sbjct: 20 GSIAGACGKVIEFPFDTVKVRLQTQ------ASNVFPTTWSCIKFTYQNEGIARGFFQGI 73 Query: 219 GTKIVQSVFAASVLFMVKEELVKFV 145 + +V + + LF+ + KF+ Sbjct: 74 ASPLVGACLENATLFVSYNQCSKFL 98
>ODC2_YEAST (Q99297) Mitochondrial 2-oxodicarboxylate carrier 2| Length = 307 Score = 51.6 bits (122), Expect = 2e-06 Identities = 37/153 (24%), Positives = 70/153 (45%), Gaps = 2/153 (1%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGLIPTLIM--VCNPSIQFMIYETLSKRLQSKRSGKRFPKK 427 G + +++ + GI G +KG+ T+ + N +IY+ + +K G++ Sbjct: 155 GPMDCLKKTIKNEGIMGLYKGIESTMWRNALWNGGYFGVIYQVRNSMPVAKTKGQK---- 210 Query: 426 NITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYE 247 + GAI T++ P VVKSR+Q+ + +A +Y L ++L + R E Sbjct: 211 ---TRNDLIAGAIGGTVGTMLNTPFDVVKSRIQSVDAVS-SAVKKYNWCLPSLLVIYREE 266 Query: 246 GLHGFYKGMGTKIVQSVFAASVLFMVKEELVKF 148 G YKG K+ + S++ +V ++ F Sbjct: 267 GFRALYKGFVPKVCRLAPGGSLMLVVFTGMMNF 299 Score = 46.6 bits (109), Expect = 6e-05 Identities = 26/90 (28%), Positives = 44/90 (48%), Gaps = 5/90 (5%) Frame = -3 Query: 405 FLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAA-----SRYTGTLDAILKMIRYEGL 241 F+ GA+A + V YPL VVK+R Q + AA RY G +D + K+++ EG Sbjct: 16 FISGAVAGISELTVMYPLDVVKTRFQLEVTTPTAAAVGKQVERYNGVIDCLKKIVKKEGF 75 Query: 240 HGFYKGMGTKIVQSVFAASVLFMVKEELVK 151 Y+G+ + ++ + F ++ K Sbjct: 76 SRLYRGISSPMLMEAPKRATKFACNDQYQK 105 Score = 43.5 bits (101), Expect = 5e-04 Identities = 33/136 (24%), Positives = 56/136 (41%), Gaps = 9/136 (6%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGLIPTLIM---------VCNPSIQFMIYETLSKRLQSKRS 448 G I ++++ ++ G S ++G+ ++M CN Y+ + K L Sbjct: 61 GVIDCLKKIVKKEGFSRLYRGISSPMLMEAPKRATKFACNDQ-----YQKIFKNL----- 110 Query: 447 GKRFPKKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAI 268 F T GA A + V P ++K R+Q + S Y G +D + Sbjct: 111 ---FNTNETTQKISIAAGASAGMTEAAVIVPFELIKIRMQ-------DVKSSYLGPMDCL 160 Query: 267 LKMIRYEGLHGFYKGM 220 K I+ EG+ G YKG+ Sbjct: 161 KKTIKNEGIMGLYKGI 176
>CMC3_CAEEL (Q19529) Probable calcium-binding mitochondrial carrier F17E5.2| Length = 531 Score = 51.6 bits (122), Expect = 2e-06 Identities = 35/151 (23%), Positives = 71/151 (47%), Gaps = 1/151 (0%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGLIPTLI-MVCNPSIQFMIYETLSKRLQSKRSGKRFPKKN 424 G ++Y + GI F+KG +P L+ ++ I +YE+L + P Sbjct: 379 GMFHFAHKMYTKEGIKCFYKGYLPNLLGIIPYAGIDLTVYESLKSMYTKYYTEHTEPG-- 436 Query: 423 ITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEG 244 + + G + + +YPL +V++RLQA+ +N+ T + +++ EG Sbjct: 437 --VLALLACGTCSSTCGQLASYPLALVRTRLQARAISPKNSTQPDT-MVGQFKHILQTEG 493 Query: 243 LHGFYKGMGTKIVQSVFAASVLFMVKEELVK 151 G Y+G+ ++ + A S+ ++V E++ K Sbjct: 494 FTGLYRGITPNFMKVIPAVSISYVVYEKVRK 524
>CMC1_DROME (Q9VA73) Calcium-binding mitochondrial carrier Aralar1| Length = 695 Score = 51.6 bits (122), Expect = 2e-06 Identities = 40/127 (31%), Positives = 62/127 (48%), Gaps = 1/127 (0%) Frame = -3 Query: 576 VYRESGISGFWKGLIPTLIM-VCNPSIQFMIYETLSKRLQSKRSGKRFPKKNITAMEVFL 400 V RE G+ G +KG L+ V +I F Y +K + + + G P + A Sbjct: 486 VVRELGLFGLYKGARACLLRDVPFSAIYFPTYAH-TKAMMADKDGYNHPLTLLAA----- 539 Query: 399 LGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFYKGM 220 GAIA + A + P V+K+RLQ + R+ + YTG DA K++ EG F+KG Sbjct: 540 -GAIAGVPAASLVTPADVIKTRLQV---VARSGQTTYTGVWDATKKIMAEEGPRAFWKGT 595 Query: 219 GTKIVQS 199 ++ +S Sbjct: 596 AARVFRS 602 Score = 50.1 bits (118), Expect = 5e-06 Identities = 39/137 (28%), Positives = 62/137 (45%), Gaps = 1/137 (0%) Frame = -3 Query: 582 REVYRESGISGFWKGLIPTLIMVC-NPSIQFMIYETLSKRLQSKRSGKRFPKKNITAMEV 406 ++V R G G ++GL+P L+ V +I+ + + + +L K K NI Sbjct: 392 KKVVRHEGFMGLYRGLLPQLMGVAPEKAIKLTVNDLVRDKLTDK-------KGNIPTWAE 444 Query: 405 FLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFYK 226 L G A V T PL +VK RLQ EI +G+ ++R GL G YK Sbjct: 445 VLAGGCAGASQVVFTNPLEIVKIRLQVAGEIA-------SGSKIRAWSVVRELGLFGLYK 497 Query: 225 GMGTKIVQSVFAASVLF 175 G +++ V +++ F Sbjct: 498 GARACLLRDVPFSAIYF 514 Score = 42.0 bits (97), Expect = 0.001 Identities = 24/63 (38%), Positives = 38/63 (60%), Gaps = 1/63 (1%) Frame = -3 Query: 405 FLLGAIA-KLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFY 229 F LG+ A +GATVV YP+ +VK+R+Q ++ Y + D K++R+EG G Y Sbjct: 346 FTLGSFAGAVGATVV-YPIDLVKTRMQNQRAGSYIGEVAYRNSWDCFKKVVRHEGFMGLY 404 Query: 228 KGM 220 +G+ Sbjct: 405 RGL 407
>GHC1_MOUSE (Q9D6M3) Mitochondrial glutamate carrier 1 (GC-1) (Glutamate/H(+)| symporter 1) (Solute carrier family 25 member 22) Length = 323 Score = 51.6 bits (122), Expect = 2e-06 Identities = 47/129 (36%), Positives = 63/129 (48%) Frame = -3 Query: 609 RPYGTIQAIREVYRESGISGFWKGLIPTLIMVCNPSIQFMIYETLSKRLQSKRSGKRFPK 430 RP T Q R++ R GI+G +KGL TL+ SI +Y L L + G+ + Sbjct: 167 RPTAT-QLTRDLLRNHGIAGLYKGLGATLLRDVPFSI---VYFPLFANLN--QLGRPSSE 220 Query: 429 KNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRY 250 + FL G +A A V P VVK+RLQ+ E G N Y+G LD K+ R+ Sbjct: 221 EKSPFYVSFLAGCVAGSAAAVAVNPCDVVKTRLQS-LERGVN-EDTYSGFLDCARKIWRH 278 Query: 249 EGLHGFYKG 223 EG F KG Sbjct: 279 EGPSAFLKG 287 Score = 39.7 bits (91), Expect = 0.007 Identities = 23/74 (31%), Positives = 34/74 (45%) Frame = -3 Query: 429 KNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRY 250 K I+ + G IA L +P+ + K+RLQ +Q N Y D ++K IR Sbjct: 4 KQISLPAKLINGGIAGLIGVTCVFPIDLAKTRLQNQQ----NGQRMYASMSDCLIKTIRS 59 Query: 249 EGLHGFYKGMGTKI 208 EG G Y+G + Sbjct: 60 EGYFGMYRGAAVNL 73 Score = 30.8 bits (68), Expect = 3.3 Identities = 37/157 (23%), Positives = 60/157 (38%), Gaps = 25/157 (15%) Frame = -3 Query: 570 RESGISGFWKGLIPTLIMVCNPSIQFMIYETLSKRLQSKRSGKRFPKKNITAMEVFLLGA 391 R G G ++G L +V P + R Q + G++ +T + L G Sbjct: 58 RSEGYFGMYRGAAVNLTLV-TPEKAIKLAANDFFRHQLSKDGQK-----LTLPKEMLAGC 111 Query: 390 IAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILK----------------- 262 A +VT P+ ++K +LQ + GR AA R A L Sbjct: 112 GAGTCQVIVTTPMEMLKIQLQ---DAGRIAAQRKILAAQAQLSAQGGAQPSVEAPAPPRP 168 Query: 261 --------MIRYEGLHGFYKGMGTKIVQSVFAASVLF 175 ++R G+ G YKG+G +++ V + V F Sbjct: 169 TATQLTRDLLRNHGIAGLYKGLGATLLRDVPFSIVYF 205
>ORNT2_HUMAN (Q9BXI2) Mitochondrial ornithine transporter 2 (Solute carrier| family 25 member 2) Length = 301 Score = 51.2 bits (121), Expect = 2e-06 Identities = 36/143 (25%), Positives = 67/143 (46%), Gaps = 2/143 (1%) Frame = -3 Query: 585 IREVYRESGISGFWKGLIPTLIMVCNPSIQFMI--YETLSKRLQSKRSGKRFPKKNITAM 412 ++ + ++ G GF+ GL TL+ P F YE S RS K + + Sbjct: 157 VKGILKKDGPLGFYHGLSSTLLQE-GPGYFFFFGGYELSRSFFASGRS-----KDELGPV 210 Query: 411 EVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGF 232 + L G +A + ++ +P+ +KSR+Q G+ A G + +L ++R EG+ Sbjct: 211 HLMLSGGVAGICLWLIVFPVDCIKSRIQVLSMYGKQA-----GFIGTLLSVVRNEGIVAL 265 Query: 231 YKGMGTKIVQSVFAASVLFMVKE 163 Y G+ +++++ A LF+ E Sbjct: 266 YSGLKATMIRAIPANGALFVAYE 288 Score = 38.5 bits (88), Expect = 0.016 Identities = 24/75 (32%), Positives = 32/75 (42%) Frame = -3 Query: 396 GAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFYKGMG 217 GA + P +K ++Q ++ Y G D LK GL GFYKG G Sbjct: 16 GAAGGTACVLTGQPFDTIKVKMQTFPDL-------YKGLTDCFLKTYAQVGLRGFYKGTG 68 Query: 216 TKIVQSVFAASVLFM 172 ++ V SVLFM Sbjct: 69 PALMAYVAENSVLFM 83
>ADT1_BOVIN (P02722) ADP/ATP translocase 1 (Adenine nucleotide translocator 1)| (ANT 1) (ADP,ATP carrier protein 1) (Solute carrier family 25 member 4) (ADP,ATP carrier protein, heart isoform T1) Length = 297 Score = 51.2 bits (121), Expect = 2e-06 Identities = 40/154 (25%), Positives = 73/154 (47%), Gaps = 2/154 (1%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGLIPTLIMVCNPSIQ-FMIYETLSKRLQSKRSGKRFPKKN 424 G I ++++ G+ G ++G N S+Q +IY + G KN Sbjct: 155 GLGNCITKIFKSDGLRGLYQGF--------NVSVQGIIIYRAAYFGVYDTAKGMLPDPKN 206 Query: 423 ITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAAS-RYTGTLDAILKMIRYE 247 + + +++ A +V+YP V+ R+ + GR A YTGT+D K+ + E Sbjct: 207 VHIIVSWMIAQTVTAVAGLVSYPFDTVRRRMMMQS--GRKGADIMYTGTVDCWRKIAKDE 264 Query: 246 GLHGFYKGMGTKIVQSVFAASVLFMVKEELVKFV 145 G F+KG + +++ + A VL ++ +E+ KFV Sbjct: 265 GPKAFFKGAWSNVLRGMGGAFVL-VLYDEIKKFV 297 Score = 43.1 bits (100), Expect = 6e-04 Identities = 38/152 (25%), Positives = 65/152 (42%), Gaps = 8/152 (5%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGLIPTLIMVCNPSIQFMIYETLSKR--LQSKRSGKRFPKK 427 G I + + +E G FW+G + +I ++ K+ L K+F + Sbjct: 52 GIIDCVVRIPKEQGFLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDRHKQFWR- 110 Query: 426 NITAMEVFLLGAIAKLGATVVT-----YPLLVVKSRLQAKQEIGRNAASR-YTGTLDAIL 265 + G +A GA T YPL ++RL A ++G+ AA R +TG + I Sbjct: 111 -------YFAGNLASGGAAGATSLCFVYPLDFARTRLAA--DVGKGAAQREFTGLGNCIT 161 Query: 264 KMIRYEGLHGFYKGMGTKIVQSVFAASVLFMV 169 K+ + +GL G Y+G + + + F V Sbjct: 162 KIFKSDGLRGLYQGFNVSVQGIIIYRAAYFGV 193
>ADT1_WHEAT (Q41629) ADP,ATP carrier protein 1, mitochondrial precursor| (ADP/ATP translocase 1) (Adenine nucleotide translocator 1) (ANT 1) Length = 331 Score = 50.8 bits (120), Expect = 3e-06 Identities = 34/142 (23%), Positives = 66/142 (46%), Gaps = 1/142 (0%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGL-IPTLIMVCNPSIQFMIYETLSKRLQSKRSGKRFPKKN 424 G + R+ + GI+G ++G I + ++ + F +Y++L L + Sbjct: 181 GLVDVYRKTLKSDGIAGLYRGFNISCVGIIVYRGLYFGLYDSLKPVLLTGTL-------Q 233 Query: 423 ITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEG 244 + F LG + GA + +YP+ V+ R+ A +Y +LDA ++++ EG Sbjct: 234 VCFFASFALGWLITNGAGLASYPIDTVRRRMMMTS----GEAVKYKSSLDAFQQILKKEG 289 Query: 243 LHGFYKGMGTKIVQSVFAASVL 178 +KG G I++++ A VL Sbjct: 290 AKSLFKGAGANILRAIAGAGVL 311
>ADT_CHLKE (P31692) ADP,ATP carrier protein (ADP/ATP translocase) (Adenine| nucleotide translocator) (ANT) Length = 339 Score = 50.8 bits (120), Expect = 3e-06 Identities = 33/135 (24%), Positives = 61/135 (45%), Gaps = 4/135 (2%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGLIPTLIMVCNPSIQFMIYETLSKRLQSKRSGK----RFP 433 G + V E G++ FW+G + ++ ++ K L K S K RF Sbjct: 88 GIVNCFVRVSSEQGVASFWRGNLANVVRYFPTQAFNFAFKDTIKGLFPKYSPKTDFWRFF 147 Query: 432 KKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIR 253 N+ + G +A G+ ++ YPL ++RL A ++G + +TG +D + K+++ Sbjct: 148 VVNLAS------GGLAGAGSLLIVYPLDFARTRLAA--DVGSGKSREFTGLVDCLSKVVK 199 Query: 252 YEGLHGFYKGMGTKI 208 G Y+G G + Sbjct: 200 RGGPMALYQGFGVSV 214 Score = 44.7 bits (104), Expect = 2e-04 Identities = 35/154 (22%), Positives = 70/154 (45%), Gaps = 2/154 (1%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGL-IPTLIMVCNPSIQFMIYETLSKRL-QSKRSGKRFPKK 427 G + + +V + G ++G + ++ F +Y+T L + +R+ F K Sbjct: 189 GLVDCLSKVVKRGGPMALYQGFGVSVQGIIVYRGAYFGLYDTAKGVLFKDERTANFFAK- 247 Query: 426 NITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYE 247 + + GA V++YP V+ RL + +Y GT+D K+ + E Sbjct: 248 -------WAVAQAVTAGAGVLSYPFDTVRRRLMMQS----GGERQYNGTIDCWRKVAQQE 296 Query: 246 GLHGFYKGMGTKIVQSVFAASVLFMVKEELVKFV 145 G+ F+KG + +++ A VL ++ +E+ KF+ Sbjct: 297 GMKAFFKGAWSNVLRGAGGAFVL-VLYDEIKKFI 329
>ADT1_MOUSE (P48962) ADP/ATP translocase 1 (Adenine nucleotide translocator 1)| (ANT 1) (ADP,ATP carrier protein 1) (Solute carrier family 25 member 4) (ADP,ATP carrier protein, heart/skeletal muscle isoform T1) (mANC1) Length = 297 Score = 50.8 bits (120), Expect = 3e-06 Identities = 37/154 (24%), Positives = 75/154 (48%), Gaps = 2/154 (1%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGL-IPTLIMVCNPSIQFMIYETLSKRLQSKRSGKRFPKKN 424 G + ++++ G+ G ++G + ++ + F +Y+T L KN Sbjct: 155 GLGDCLTKIFKSDGLKGLYQGFSVSVQGIIIYRAAYFGVYDTAKGMLPDP--------KN 206 Query: 423 ITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAAS-RYTGTLDAILKMIRYE 247 + + +++ A +V+YP V+ R+ + GR A YTGTLD K+ + E Sbjct: 207 VHIIVSWMIAQSVTAVAGLVSYPFDTVRRRMMMQS--GRKGADIMYTGTLDCWRKIAKDE 264 Query: 246 GLHGFYKGMGTKIVQSVFAASVLFMVKEELVKFV 145 G + F+KG + +++ + A VL ++ +E+ K+V Sbjct: 265 GANAFFKGAWSNVLRGMGGAFVL-VLYDEIKKYV 297 Score = 39.7 bits (91), Expect = 0.007 Identities = 35/152 (23%), Positives = 64/152 (42%), Gaps = 8/152 (5%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGLIPTLIMVCNPSIQFMIYETLSKR--LQSKRSGKRFPKK 427 G I + + +E G FW+G + +I ++ K+ L K+F + Sbjct: 52 GIIDCVVRIPKEQGFLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDRHKQFWR- 110 Query: 426 NITAMEVFLLGAIAKLGATVVT-----YPLLVVKSRLQAKQEIGRNAASR-YTGTLDAIL 265 + G +A GA T YPL ++RL A ++G+ ++ R + G D + Sbjct: 111 -------YFAGNLASGGAAGATSLCFVYPLDFARTRLAA--DVGKGSSQREFNGLGDCLT 161 Query: 264 KMIRYEGLHGFYKGMGTKIVQSVFAASVLFMV 169 K+ + +GL G Y+G + + + F V Sbjct: 162 KIFKSDGLKGLYQGFSVSVQGIIIYRAAYFGV 193
>YQ51_CAEEL (Q09461) Putative mitochondrial carrier C16C10.1| Length = 360 Score = 50.4 bits (119), Expect = 4e-06 Identities = 38/139 (27%), Positives = 68/139 (48%), Gaps = 18/139 (12%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGLIPTLIMVCNPSI-QFMIYETLSKRLQSKRSGKR-FPKK 427 GT AI ++ R GI W GL PT++M ++ F Y+ LS L+ K +R F + Sbjct: 108 GTADAIVKIARHEGIRSLWSGLSPTMVMALPATVFYFTTYDNLSVWLKKKMCCRRAFSPE 167 Query: 426 NITAME---VFLLGAIAKLGATVVTYPLLVVKSRLQAKQ----EIG---------RNAAS 295 T + + G +A+ A V P+ ++++++Q+K+ EIG + +S Sbjct: 168 KWTPPDWSAAAVAGIVARTIAVTVVSPIEMIRTKMQSKRLTYHEIGHLVRSSMATKGISS 227 Query: 294 RYTGTLDAILKMIRYEGLH 238 Y G +L+ I + G++ Sbjct: 228 FYLGWTPTMLRDIPFSGIY 246 Score = 37.0 bits (84), Expect = 0.045 Identities = 31/129 (24%), Positives = 55/129 (42%), Gaps = 1/129 (0%) Frame = -3 Query: 585 IREVYRESGISGFWKGLIPTLIM-VCNPSIQFMIYETLSKRLQSKRSGKRFPKKNITAME 409 +R GIS F+ G PT++ + I + Y+ LQ ++ P + Sbjct: 216 VRSSMATKGISSFYLGWTPTMLRDIPFSGIYWAGYDLFKTNLQRRQGPDHNP-----FVV 270 Query: 408 VFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFY 229 F+ GA A + A++ T+P V+K+ Q + IG + I M G+ F Sbjct: 271 SFVSGAAAGVVASIFTHPFDVIKTNCQIR--IGGSIDDMNKSITTVIKDMYHSRGISAFS 328 Query: 228 KGMGTKIVQ 202 G+ ++V+ Sbjct: 329 SGLVPRLVK 337 Score = 32.3 bits (72), Expect = 1.1 Identities = 14/45 (31%), Positives = 25/45 (55%) Frame = -3 Query: 291 YTGTLDAILKMIRYEGLHGFYKGMGTKIVQSVFAASVLFMVKEEL 157 + GT DAI+K+ R+EG+ + G+ +V ++ A F + L Sbjct: 106 FRGTADAIVKIARHEGIRSLWSGLSPTMVMALPATVFYFTTYDNL 150 Score = 30.8 bits (68), Expect = 3.3 Identities = 15/33 (45%), Positives = 21/33 (63%) Frame = -3 Query: 585 IREVYRESGISGFWKGLIPTLIMVCNPSIQFMI 487 I+++Y GIS F GL+P L+ V +PS MI Sbjct: 315 IKDMYHSRGISAFSSGLVPRLVKV-SPSCAIMI 346
>MFRN_CAEEL (Q23125) Mitoferrin| Length = 312 Score = 50.4 bits (119), Expect = 4e-06 Identities = 48/166 (28%), Positives = 77/166 (46%), Gaps = 11/166 (6%) Frame = -3 Query: 606 PYGT-IQAIREVYRESGISGFWKGLIPTLIM-VCNPSIQFMIYETLSKRLQSKRSGKRFP 433 PYG+ ++ R VY G++ F++ L M V +I FM YE L + K P Sbjct: 148 PYGSSLECARCVYNREGVAAFYRSYTTQLAMNVPFQAIHFMSYEFWQHVLNPEH--KYDP 205 Query: 432 KKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASR---------YTGT 280 K ++ A G +A A +T P+ VK+ L +Q + A+R Y G Sbjct: 206 KSHLIA------GGLAGGLAAALTTPMDCVKTVLNTQQAAEADPANRRIFLQARYRYRGI 259 Query: 279 LDAILKMIRYEGLHGFYKGMGTKIVQSVFAASVLFMVKEELVKFVI 142 DA+ + GL GF G+ +++ V A ++ + V EL KF++ Sbjct: 260 SDAVRTIYSQRGLSGFSCGLQARVIFQVPATALSWSV-YELFKFML 304 Score = 32.0 bits (71), Expect = 1.5 Identities = 27/114 (23%), Positives = 47/114 (41%) Frame = -3 Query: 504 SIQFMIYETLSKRLQSKRSGKRFPKKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQA 325 ++ F +YE + L +G + + G +A L + P VVK R+Q Sbjct: 91 ALYFTVYEKMKGYLTGNSAG------HSNTLAYGASGVVATLIHDAIMNPAEVVKQRMQM 144 Query: 324 KQEIGRNAASRYTGTLDAILKMIRYEGLHGFYKGMGTKIVQSVFAASVLFMVKE 163 A S Y +L+ + EG+ FY+ T++ +V ++ FM E Sbjct: 145 -------AFSPYGSSLECARCVYNREGVAAFYRSYTTQLAMNVPFQAIHFMSYE 191
>OAC1_YEAST (P32332) Mitochondrial oxaloacetate transport protein| (Mitochondrial carrier protein PMT) Length = 324 Score = 50.4 bits (119), Expect = 4e-06 Identities = 36/159 (22%), Positives = 68/159 (42%), Gaps = 1/159 (0%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGLIPTLIMV-CNPSIQFMIYETLSKRLQSKRSGKRFPKKN 424 G + +++ G+ G ++G+ ++ S+Q IY T L K P + Sbjct: 173 GVWNGLVTIFKTEGVKGLFRGIDAAILRTGAGSSVQLPIYNTAKNILVKNDLMKDGPALH 232 Query: 423 ITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEG 244 +TA I+ LG VV P V+ +R+ ++ Y G +D ++K +R EG Sbjct: 233 LTA------STISGLGVAVVMNPWDVILTRIYNQK------GDLYKGPIDCLVKTVRIEG 280 Query: 243 LHGFYKGMGTKIVQSVFAASVLFMVKEELVKFVILLVAR 127 + YKG ++ + + E+ +K V + +R Sbjct: 281 VTALYKGFAAQVFRIAPHTIMCLTFMEQTMKLVYSIESR 319 Score = 48.5 bits (114), Expect = 2e-05 Identities = 40/159 (25%), Positives = 72/159 (45%), Gaps = 11/159 (6%) Frame = -3 Query: 594 IQAIREVYRESGISGFWKGLIPTLI-MVCNPSIQFMIYETLSKRLQSKRSGKRFPKKNIT 418 IQ + +++ GI G KGL I + + YE + L + P K + Sbjct: 68 IQGMAVIFKNEGIKGLQKGLNAAYIYQIGLNGSRLGFYEPIRSSLNQLFFPDQEPHKVQS 127 Query: 417 AMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQE-IGRNAASRYTGTLDAILKMIRYEGL 241 GA + + V+ PL +VK+RLQ+ E I + YTG + ++ + + EG+ Sbjct: 128 VGVNVFSGAASGIIGAVIGSPLFLVKTRLQSYSEFIKIGEQTHYTGVWNGLVTIFKTEGV 187 Query: 240 HGFYKGMGTKIVQSVFAASVL---------FMVKEELVK 151 G ++G+ I+++ +SV +VK +L+K Sbjct: 188 KGLFRGIDAAILRTGAGSSVQLPIYNTAKNILVKNDLMK 226 Score = 42.4 bits (98), Expect = 0.001 Identities = 24/89 (26%), Positives = 44/89 (49%) Frame = -3 Query: 462 QSKRSGKRFPKKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTG 283 Q K+ K +K I+ F+ G +A A VT P+ ++K R+Q + E+ +AA Y Sbjct: 8 QDKQIEKTAAQK-ISKFGSFVAGGLAACIAVTVTNPIELIKIRMQLQGEMSASAAKVYKN 66 Query: 282 TLDAILKMIRYEGLHGFYKGMGTKIVQSV 196 + + + + EG+ G KG+ + + Sbjct: 67 PIQGMAVIFKNEGIKGLQKGLNAAYIYQI 95
>ADT1_ARATH (P31167) ADP,ATP carrier protein 1, mitochondrial precursor| (ADP/ATP translocase 1) (Adenine nucleotide translocator 1) (ANT 1) Length = 381 Score = 50.4 bits (119), Expect = 4e-06 Identities = 35/142 (24%), Positives = 66/142 (46%), Gaps = 1/142 (0%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGL-IPTLIMVCNPSIQFMIYETLSKRLQSKRSGKRFPKKN 424 G + R+ + GI+G ++G I + ++ + F +Y+++ L + F Sbjct: 231 GLVDVYRKTLKTDGIAGLYRGFNISCVGIIVYRGLYFGLYDSVKPVLLTGDLQDSF---- 286 Query: 423 ITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEG 244 F LG + GA + +YP+ V+ R+ A +Y +LDA ++++ EG Sbjct: 287 ---FASFALGWVITNGAGLASYPIDTVRRRMMMTS----GEAVKYKSSLDAFKQILKNEG 339 Query: 243 LHGFYKGMGTKIVQSVFAASVL 178 +KG G I+++V A VL Sbjct: 340 AKSLFKGAGANILRAVAGAGVL 361
>ORNT1_MOUSE (Q9WVD5) Mitochondrial ornithine transporter 1 (Solute carrier| family 25 member 15) Length = 301 Score = 50.1 bits (118), Expect = 5e-06 Identities = 37/143 (25%), Positives = 64/143 (44%), Gaps = 2/143 (1%) Frame = -3 Query: 585 IREVYRESGISGFWKGLIPTLIMVCNPSIQFMI--YETLSKRLQSKRSGKRFPKKNITAM 412 ++E++R+ G GF+ GL TL+ P F YE S RS K + + Sbjct: 157 VKEIFRKDGPLGFYHGLSSTLLREV-PGYFFFFGGYELSRSFFASGRS-----KDELGPV 210 Query: 411 EVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGF 232 + L G + + YP+ +KSR+Q G+ TG + L +++ EG+ Sbjct: 211 PLMLSGGFGGICLWLAVYPVDCIKSRIQVLSMTGKQ-----TGLVRTFLSIVKNEGITAL 265 Query: 231 YKGMGTKIVQSVFAASVLFMVKE 163 Y G+ ++++ A LF+ E Sbjct: 266 YSGLKPTMIRAFPANGALFLAYE 288 Score = 35.0 bits (79), Expect = 0.17 Identities = 21/75 (28%), Positives = 31/75 (41%) Frame = -3 Query: 396 GAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFYKGMG 217 GA + P +K ++Q ++ Y G D LK G GFYKG Sbjct: 16 GAAGGTACVLTGQPFDTMKVKMQTFPDL-------YRGLTDCCLKTYSQVGFRGFYKGTS 68 Query: 216 TKIVQSVFAASVLFM 172 ++ ++ SVLFM Sbjct: 69 PALIANIAENSVLFM 83
>ADT1_RABIT (O46373) ADP/ATP translocase 1 (Adenine nucleotide translocator 1)| (ANT 1) (ADP,ATP carrier protein 1) (Solute carrier family 25 member 4) (30 kDa calsequestrin-binding protein) (CSQ-binding 30 kDa protein) Length = 297 Score = 50.1 bits (118), Expect = 5e-06 Identities = 38/154 (24%), Positives = 73/154 (47%), Gaps = 2/154 (1%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGLIPTLIMVCNPSIQ-FMIYETLSKRLQSKRSGKRFPKKN 424 G + ++++ G+ G ++G N S+Q +IY + G KN Sbjct: 155 GLGNCLTKIFKSDGLRGLYQGF--------NVSVQGIIIYRAAYFGVYDTAKGMLPDPKN 206 Query: 423 ITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAAS-RYTGTLDAILKMIRYE 247 + + +++ A +V+YP V+ R+ + GR A YTGT+D K+ + E Sbjct: 207 VHIIVSWMIAQTVTAVAGLVSYPFDTVRRRMMMQS--GRKGADIMYTGTVDCWKKIAKDE 264 Query: 246 GLHGFYKGMGTKIVQSVFAASVLFMVKEELVKFV 145 G F+KG + +++ + A VL ++ +E+ K+V Sbjct: 265 GAKAFFKGAWSNVLRGMGGAFVL-VLYDEIKKYV 297 Score = 40.8 bits (94), Expect = 0.003 Identities = 36/152 (23%), Positives = 65/152 (42%), Gaps = 8/152 (5%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGLIPTLIMVCNPSIQFMIYETLSKR--LQSKRSGKRFPKK 427 G I + + +E G FW+G + +I ++ K+ L K+F + Sbjct: 52 GIIDCVVRIPKEQGFLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDRHKQFWR- 110 Query: 426 NITAMEVFLLGAIAKLGATVVT-----YPLLVVKSRLQAKQEIGRNAASR-YTGTLDAIL 265 + G +A GA T YPL ++RL A ++G+ AA R ++G + + Sbjct: 111 -------YFAGNLASGGAAGATSLCFVYPLDFARTRLAA--DVGKGAAQREFSGLGNCLT 161 Query: 264 KMIRYEGLHGFYKGMGTKIVQSVFAASVLFMV 169 K+ + +GL G Y+G + + + F V Sbjct: 162 KIFKSDGLRGLYQGFNVSVQGIIIYRAAYFGV 193
>ADT1_HUMAN (P12235) ADP/ATP translocase 1 (Adenine nucleotide translocator 1)| (ANT 1) (ADP,ATP carrier protein 1) (Solute carrier family 25 member 4) (ADP,ATP carrier protein, heart/skeletal muscle isoform T1) Length = 297 Score = 50.1 bits (118), Expect = 5e-06 Identities = 39/155 (25%), Positives = 73/155 (47%), Gaps = 2/155 (1%) Frame = -3 Query: 603 YGTIQAIREVYRESGISGFWKGLIPTLIMVCNPSIQ-FMIYETLSKRLQSKRSGKRFPKK 427 +G I ++++ G+ G ++G N S+Q +IY + G K Sbjct: 154 HGLGDCIIKIFKSDGLRGLYQGF--------NVSVQGIIIYRAAYFGVYDTAKGMLPDPK 205 Query: 426 NITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAAS-RYTGTLDAILKMIRY 250 N+ +++ A +V+YP V+ R+ + GR A YTGT+D K+ + Sbjct: 206 NVHIFVSWMIAQSVTAVAGLVSYPFDTVRRRMMMQS--GRKGADIMYTGTVDCWRKIAKD 263 Query: 249 EGLHGFYKGMGTKIVQSVFAASVLFMVKEELVKFV 145 EG F+KG + +++ + A VL ++ +E+ K+V Sbjct: 264 EGAKAFFKGAWSNVLRGMGGAFVL-VLYDEIKKYV 297 Score = 43.5 bits (101), Expect = 5e-04 Identities = 35/150 (23%), Positives = 63/150 (42%), Gaps = 6/150 (4%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGLIPTLIMVCNPSIQFMIYETLSKRL-----QSKRSGKRF 436 G I + + +E G FW+G + +I ++ K+L + R+ Sbjct: 52 GIIDCVVRIPKEQGFLSFWRGNLANVIRYFPTQALNFAFKDKYKQLFLGGVDRHKQFWRY 111 Query: 435 PKKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASR-YTGTLDAILKM 259 N+ + G A + YPL ++RL A ++G+ AA R + G D I+K+ Sbjct: 112 FAGNLAS------GGAAGATSLCFVYPLDFARTRLAA--DVGKGAAQREFHGLGDCIIKI 163 Query: 258 IRYEGLHGFYKGMGTKIVQSVFAASVLFMV 169 + +GL G Y+G + + + F V Sbjct: 164 FKSDGLRGLYQGFNVSVQGIIIYRAAYFGV 193
>ADT1_MAIZE (P04709) ADP,ATP carrier protein 1, mitochondrial precursor| (ADP/ATP translocase 1) (Adenine nucleotide translocator 1) (ANT 1) Length = 387 Score = 49.7 bits (117), Expect = 7e-06 Identities = 33/142 (23%), Positives = 66/142 (46%), Gaps = 1/142 (0%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGL-IPTLIMVCNPSIQFMIYETLSKRLQSKRSGKRFPKKN 424 G + R+ + GI+G ++G I + ++ + F +Y+++ + + F Sbjct: 237 GLVDVYRKTLKSDGIAGLYRGFNISCVGIIVYRGLYFGLYDSIKPVVLTGNLQDNF---- 292 Query: 423 ITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEG 244 F LG + GA + +YP+ V+ R+ A +Y +LDA ++++ EG Sbjct: 293 ---FASFALGWLITNGAGLASYPIDTVRRRMMMTS----GEAVKYKSSLDAFQQILKKEG 345 Query: 243 LHGFYKGMGTKIVQSVFAASVL 178 +KG G I++++ A VL Sbjct: 346 PKSLFKGAGANILRAIAGAGVL 367 Score = 35.0 bits (79), Expect = 0.17 Identities = 32/162 (19%), Positives = 61/162 (37%), Gaps = 7/162 (4%) Frame = -3 Query: 606 PY-GTIQAIREVYRESGISGFWKGLIPTLIMVCNPSIQFMIYETLSKRLQSKRSGKRFPK 430 PY G + + ++ G S W+G +I ++ KRL + K Sbjct: 130 PYKGIVDCFKRTIKDEGFSSLWRGNTANVIRYFPTQALNFAFKDYFKRLFNF-------K 182 Query: 429 KNITAMEVFLLGAIAKLGAT-----VVTYPLLVVKSRLQAKQEIGRNAASR-YTGTLDAI 268 K+ + G +A GA Y L ++RL + + R + G +D Sbjct: 183 KDRDGYWKWFAGNLASGGAAGASSLFFVYSLDYARTRLANDAKAAKGGGERQFNGLVDVY 242 Query: 267 LKMIRYEGLHGFYKGMGTKIVQSVFAASVLFMVKEELVKFVI 142 K ++ +G+ G Y+G V + + F + + + V+ Sbjct: 243 RKTLKSDGIAGLYRGFNISCVGIIVYRGLYFGLYDSIKPVVL 284
>ADT_ORYSA (P31691) ADP,ATP carrier protein, mitochondrial precursor (ADP/ATP| translocase) (Adenine nucleotide translocator) (ANT) Length = 382 Score = 49.7 bits (117), Expect = 7e-06 Identities = 33/142 (23%), Positives = 66/142 (46%), Gaps = 1/142 (0%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGL-IPTLIMVCNPSIQFMIYETLSKRLQSKRSGKRFPKKN 424 G + R+ + GI+G ++G I + ++ + F +Y++L + + F Sbjct: 232 GLVDVYRKTLKSDGIAGLYRGFNISCVGIIVYRGLYFGMYDSLKPVVLTGSLQDNF---- 287 Query: 423 ITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEG 244 F LG + GA + +YP+ V+ R+ A +Y ++DA ++++ EG Sbjct: 288 ---FASFALGWLITNGAGLASYPIDTVRRRMMMTS----GEAVKYKSSMDAFSQILKNEG 340 Query: 243 LHGFYKGMGTKIVQSVFAASVL 178 +KG G I++++ A VL Sbjct: 341 AKSLFKGAGANILRAIAGAGVL 362
>ADT2_MAIZE (P12857) ADP,ATP carrier protein 2, mitochondrial precursor| (ADP/ATP translocase 2) (Adenine nucleotide translocator 2) (ANT 2) Length = 387 Score = 49.3 bits (116), Expect = 9e-06 Identities = 33/142 (23%), Positives = 66/142 (46%), Gaps = 1/142 (0%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGL-IPTLIMVCNPSIQFMIYETLSKRLQSKRSGKRFPKKN 424 G + R+ + GI+G ++G I + ++ + F +Y+++ + + F Sbjct: 237 GLVDVYRKTLKSDGIAGLYRGFNISCVGIIVYRGLYFGLYDSIKPVVLTGSLQDNF---- 292 Query: 423 ITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEG 244 F LG + GA + +YP+ V+ R+ A +Y +LDA ++++ EG Sbjct: 293 ---FASFALGWLITNGAGLASYPIDTVRRRMMMTS----GEAVKYKSSLDAFQQILKKEG 345 Query: 243 LHGFYKGMGTKIVQSVFAASVL 178 +KG G I++++ A VL Sbjct: 346 PKSLFKGAGANILRAIAGAGVL 367
>YD1K_SCHPO (Q10248) Putative mitochondrial carrier C4G9.20c| Length = 302 Score = 49.3 bits (116), Expect = 9e-06 Identities = 38/154 (24%), Positives = 68/154 (44%), Gaps = 1/154 (0%) Frame = -3 Query: 603 YGTIQAIREVYRESGISGFWKGLIPTLIMVCNP-SIQFMIYETLSKRLQSKRSGKRFPKK 427 +G I+++ + G+SG KG PT + + F+ YE L K +K + Sbjct: 151 HGPWDCIKKISSQYGLSGIMKGYNPTAAREAHGLGMYFLAYEALVKNTMAKHH--LTDRS 208 Query: 426 NITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYE 247 ++ + GA A + YP +VKS++Q G + + Y + + Sbjct: 209 QTPGWKLCVFGAGAGYAMWLAAYPFDIVKSKIQTD---GFLSKATYKNSWQCAKGIYTKA 265 Query: 246 GLHGFYKGMGTKIVQSVFAASVLFMVKEELVKFV 145 GL GFY+G +V++ A +V F V E + + + Sbjct: 266 GLRGFYRGFVPVLVRAAPANAVTFYVYETVSQHI 299 Score = 49.3 bits (116), Expect = 9e-06 Identities = 41/152 (26%), Positives = 71/152 (46%), Gaps = 4/152 (2%) Frame = -3 Query: 594 IQAIREVYRESGISGFWKG-LIPTLIMVCNPSIQFMIYETLSKRLQSKRSGKRFPKKN-- 424 + ++++ + G++ F+KG ++P L + SIQF +E KRF ++ Sbjct: 59 LDCVKKISKNEGLAAFYKGTVLPLLGIGFCVSIQFTTFEYC----------KRFFSRDGT 108 Query: 423 -ITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYE 247 +T + ++ GAI+ L + + P+ V+ RLQ + G+N Y G D I K+ Sbjct: 109 PVTMPQYYVSGAISGLANSFLVGPVEHVRIRLQI--QTGKNVL--YHGPWDCIKKISSQY 164 Query: 246 GLHGFYKGMGTKIVQSVFAASVLFMVKEELVK 151 GL G KG + + F+ E LVK Sbjct: 165 GLSGIMKGYNPTAAREAHGLGMYFLAYEALVK 196 Score = 42.0 bits (97), Expect = 0.001 Identities = 31/100 (31%), Positives = 45/100 (45%), Gaps = 6/100 (6%) Frame = -3 Query: 429 KNITAMEVF------LLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAI 268 KN+ A+ VF L G + +V P VK RLQ++ N + Y LD + Sbjct: 7 KNLLAILVFSFTKDFLAGVSGGVAQVLVGQPFDCVKVRLQSQS----NVSPIYNNALDCV 62 Query: 267 LKMIRYEGLHGFYKGMGTKIVQSVFAASVLFMVKEELVKF 148 K+ + EGL FYKG ++ F S+ F E +F Sbjct: 63 KKISKNEGLAAFYKGTVLPLLGIGFCVSIQFTTFEYCKRF 102
>ADT_CHLRE (P27080) ADP,ATP carrier protein (ADP/ATP translocase) (Adenine| nucleotide translocator) (ANT) Length = 308 Score = 49.3 bits (116), Expect = 9e-06 Identities = 33/142 (23%), Positives = 65/142 (45%), Gaps = 1/142 (0%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGL-IPTLIMVCNPSIQFMIYETLSKRLQSKRSGKRFPKKN 424 G + R+ GI+G ++G I + +V + F +Y++L + F Sbjct: 158 GLVDVYRKTIASDGIAGLYRGFNISCVGIVVYRGLYFGMYDSLKPVVLVGPLANNF---- 213 Query: 423 ITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEG 244 + FLLG +GA + +YP+ ++ R+ +A +Y + ++++ EG Sbjct: 214 ---LAAFLLGWGITIGAGLASYPIDTIRRRMMMTS----GSAVKYNSSFHCFQEIVKNEG 266 Query: 243 LHGFYKGMGTKIVQSVFAASVL 178 + +KG G I+++V A VL Sbjct: 267 MKSLFKGAGANILRAVAGAGVL 288
>MFRN_CAEBR (Q620A6) Mitoferrin| Length = 311 Score = 49.3 bits (116), Expect = 9e-06 Identities = 49/166 (29%), Positives = 76/166 (45%), Gaps = 11/166 (6%) Frame = -3 Query: 606 PYGT-IQAIREVYRESGISGFWKGLIPTLIM-VCNPSIQFMIYETLSKRLQSKRSGKRFP 433 PYG+ ++ R VY G + F++ L M V +I FM YE + L + K P Sbjct: 147 PYGSSLECARCVYNREGFAAFYRSYTTQLAMNVPFQAIHFMGYEFWQQVLNPEH--KYDP 204 Query: 432 KKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQ---------EIGRNAASRYTGT 280 K ++ A G +A A VT P+ VK+ L +Q I A RY G Sbjct: 205 KSHLIA------GGLAGGLAAAVTTPMDCVKTVLNTQQAAEADPSNRRIFLKARYRYRGI 258 Query: 279 LDAILKMIRYEGLHGFYKGMGTKIVQSVFAASVLFMVKEELVKFVI 142 DA+ + G+ GF G+ +++ V A ++ + V EL KF++ Sbjct: 259 SDAVRTIYSQRGMAGFSCGLQARVIFQVPATALSWSV-YELFKFML 303
>ADT1_SOLTU (P25083) ADP,ATP carrier protein, mitochondrial precursor (ADP/ATP| translocase) (Adenine nucleotide translocator) (ANT) Length = 386 Score = 49.3 bits (116), Expect = 9e-06 Identities = 35/142 (24%), Positives = 66/142 (46%), Gaps = 1/142 (0%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGL-IPTLIMVCNPSIQFMIYETLSKRLQSKRSGKRFPKKN 424 G + ++ + GI+G ++G I + ++ + F +Y++L L + F Sbjct: 236 GLVDVYKKTLKSDGIAGLYRGFNISCVGIIVYRGLYFGMYDSLKPVLLTGNLQDSF---- 291 Query: 423 ITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEG 244 F LG + GA + +YP+ V+ R+ A +Y +LDA ++++ EG Sbjct: 292 ---FASFGLGWLITNGAGLASYPIDTVRRRMMMTS----GEAVKYKSSLDAFSQIVKNEG 344 Query: 243 LHGFYKGMGTKIVQSVFAASVL 178 +KG G I+++V A VL Sbjct: 345 PKSLFKGAGANILRAVAGAGVL 366
>ADT_NEUCR (P02723) ADP,ATP carrier protein (ADP/ATP translocase) (Adenine| nucleotide translocator) (ANT) Length = 313 Score = 48.9 bits (115), Expect = 1e-05 Identities = 34/142 (23%), Positives = 62/142 (43%), Gaps = 1/142 (0%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGLIPTLI-MVCNPSIQFMIYETLSKRLQSKRSGKRFPKKN 424 G + R+ GI+G ++G P++ +V + F +Y+++ L F Sbjct: 163 GLVDVYRKTIASDGIAGLYRGFGPSVAGIVVYRGLYFGLYDSIKPVLLVGDLKNNF---- 218 Query: 423 ITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEG 244 + F LG A + +YPL ++ R+ A +Y + DA +++ EG Sbjct: 219 ---LASFALGWCVTTAAGIASYPLDTIRRRMMMTS----GEAVKYKSSFDAASQIVAKEG 271 Query: 243 LHGFYKGMGTKIVQSVFAASVL 178 + +KG G I++ V A VL Sbjct: 272 VKSLFKGAGANILRGVAGAGVL 293 Score = 38.1 bits (87), Expect = 0.020 Identities = 36/162 (22%), Positives = 67/162 (41%), Gaps = 7/162 (4%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGLIPTLIMVCNPSIQFMIYETLSKRLQSKRSGKRFPKKNI 421 G I + + G+ W+G +I ++ + L+ + K KK++ Sbjct: 59 GIIDCFKRTTADEGVMALWRGNTANVI-------RYFPTQALNFAFRDKFKKMFGYKKDV 111 Query: 420 TAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAAS-------RYTGTLDAILK 262 ++ G +A GA T LL V S A+ + +A S ++ G +D K Sbjct: 112 DGYWKWMAGNLASGGAAGAT-SLLFVYSLDYARTRLANDAKSAKKGGERQFNGLVDVYRK 170 Query: 261 MIRYEGLHGFYKGMGTKIVQSVFAASVLFMVKEELVKFVILL 136 I +G+ G Y+G G + V + F + + +K V+L+ Sbjct: 171 TIASDGIAGLYRGFGPSVAGIVVYRGLYFGLYDS-IKPVLLV 211
>ADT2_WHEAT (Q41630) ADP,ATP carrier protein 2, mitochondrial precursor| (ADP/ATP translocase 2) (Adenine nucleotide translocator 2) (ANT 2) Length = 331 Score = 48.9 bits (115), Expect = 1e-05 Identities = 34/142 (23%), Positives = 65/142 (45%), Gaps = 1/142 (0%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGL-IPTLIMVCNPSIQFMIYETLSKRLQSKRSGKRFPKKN 424 G + R+ + GI+G ++G I + ++ + F +Y++L L + Sbjct: 181 GLVDVYRKTLKSDGIAGLYRGFNISCVGIIVYRGLYFGLYDSLKPVLLTGTL-------Q 233 Query: 423 ITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEG 244 + + F LG + GA + +YP+ V+ R+ A +Y +LDA ++ EG Sbjct: 234 VCSFASFALGWLITNGAGLASYPIDTVRRRMMMTS----GEAVKYKSSLDAFQQIPAKEG 289 Query: 243 LHGFYKGMGTKIVQSVFAASVL 178 +KG G I++++ A VL Sbjct: 290 AKSLFKGAGANILRAIAGAGVL 311
>CG69_MOUSE (Q9D8K8) Mitochondrial carrier protein CGI-69 homolog| Length = 359 Score = 48.9 bits (115), Expect = 1e-05 Identities = 45/153 (29%), Positives = 67/153 (43%), Gaps = 3/153 (1%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGLIPTLIM-VCNPSIQFMIYETLSKRL--QSKRSGKRFPK 430 GT+ A ++ R G W GL TL+M V +I F Y+ L L QS S P Sbjct: 106 GTLDAFVKIVRHEGTRTLWSGLPATLVMTVPATAIYFTAYDQLKAFLCGQSLTSDLYAP- 164 Query: 429 KNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRY 250 + GA+A++G V PL +V+++LQA+ R AS ++ + Sbjct: 165 --------MVAGALARMGTVTVVSPLELVRTKLQAQHVSYRELAS-------SVQAAVTQ 209 Query: 249 EGLHGFYKGMGTKIVQSVFAASVLFMVKEELVK 151 G + G G ++ V S L+ ELVK Sbjct: 210 GGWRSLWLGWGPTALRDV-PFSALYWFNYELVK 241 Score = 43.1 bits (100), Expect = 6e-04 Identities = 18/51 (35%), Positives = 33/51 (64%) Frame = -3 Query: 297 SRYTGTLDAILKMIRYEGLHGFYKGMGTKIVQSVFAASVLFMVKEELVKFV 145 +R+TGTLDA +K++R+EG + G+ +V +V A ++ F ++L F+ Sbjct: 102 TRFTGTLDAFVKIVRHEGTRTLWSGLPATLVMTVPATAIYFTAYDQLKAFL 152
>CRC1_YEAST (Q12289) Mitochondrial carnitine carrier| Length = 327 Score = 48.9 bits (115), Expect = 1e-05 Identities = 36/144 (25%), Positives = 70/144 (48%), Gaps = 3/144 (2%) Frame = -3 Query: 594 IQAIREVYRESGISGFWKGLIPTLIMVCNPSIQFMIYETLSKRLQSKRSGKRFPKKN--I 421 IQA + + +E GI+ +KG + TL S + +SK + R ++ K+ + Sbjct: 178 IQAAKTIVKEGGIASLFKGSLATLARDGPGSALYFASYEISKNYLNSRQPRQDAGKDEPV 237 Query: 420 TAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKM-IRYEG 244 + V L G IA + + +P+ +K++LQ A+S L A ++ ++ G Sbjct: 238 NILNVCLAGGIAGMSMWLAVFPIDTIKTKLQ--------ASSTRQNMLSATKEIYLQRGG 289 Query: 243 LHGFYKGMGTKIVQSVFAASVLFM 172 + GF+ G+G +++S A + F+ Sbjct: 290 IKGFFPGLGPALLRSFPANAATFL 313 Score = 30.8 bits (68), Expect = 3.3 Identities = 29/107 (27%), Positives = 52/107 (48%), Gaps = 13/107 (12%) Frame = -3 Query: 597 TIQAIREVYRES-----------GISGFWKGLIPTLIMVCNP--SIQFMIYETLSKRLQS 457 T+ AI + +E+ + GF+KG+IP L+ V P ++ F Y+ + K+L + Sbjct: 71 TVHAITNIIKEAKTQVKGTLFTNSVKGFYKGVIPPLLGV-TPIFAVSFWGYD-VGKKLVT 128 Query: 456 KRSGKRFPKKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQE 316 + K+ +T ++ G I+ + T+VT P VK LQ + Sbjct: 129 -FNNKQGGSNELTMGQMAAAGFISAIPTTLVTAPTERVKVVLQTSSK 174
>YMC2_YEAST (P38087) Carrier protein YMC2, mitochondrial precursor| Length = 329 Score = 48.5 bits (114), Expect = 2e-05 Identities = 38/138 (27%), Positives = 65/138 (47%), Gaps = 2/138 (1%) Frame = -3 Query: 552 GFWKGLIPTLIMVCNP-SIQFMIYETLSKRLQSKRSGKRFPKKNITAMEVFLLGAIAKLG 376 G +GL PT+I + F++YE L R G + I ++ L GA + Sbjct: 197 GLMRGLFPTMIRAGHGLGTYFLVYEALVAR----EIGTGLTRNEIPPWKLCLFGAFSGTM 252 Query: 375 ATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMI-RYEGLHGFYKGMGTKIVQS 199 + YPL VVKS +Q ++ + +Y ++ + K I EG+ F+KG G +V+S Sbjct: 253 LWLTVYPLDVVKSIIQ-NDDLRK---PKYKNSISYVAKTIYAKEGIRAFFKGFGPTMVRS 308 Query: 198 VFAASVLFMVKEELVKFV 145 F+ E +++F+ Sbjct: 309 APVNGATFLTFELVMRFL 326 Score = 39.7 bits (91), Expect = 0.007 Identities = 29/99 (29%), Positives = 44/99 (44%) Frame = -3 Query: 444 KRFPKKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAIL 265 KR N ++F G I + +V P K RLQ A+ T TL+ + Sbjct: 26 KRELSSNRVLKDIFA-GTIGGIAQVLVGQPFDTTKVRLQT--------ATTRTTTLEVLR 76 Query: 264 KMIRYEGLHGFYKGMGTKIVQSVFAASVLFMVKEELVKF 148 +++ EG+ FYKG T ++ SV F V E + +F Sbjct: 77 NLVKNEGVFAFYKGALTPLLGVGICVSVQFGVNEAMKRF 115
>M2OM_MOUSE (Q9CR62) Mitochondrial 2-oxoglutarate/malate carrier protein (OGCP)| (Solute carrier family 25 member 11) Length = 313 Score = 48.5 bits (114), Expect = 2e-05 Identities = 38/126 (30%), Positives = 60/126 (47%), Gaps = 4/126 (3%) Frame = -3 Query: 588 AIREVYRESGISGFWKGLIPTLI--MVCNPSIQFMIYETLSKRLQSKRS--GKRFPKKNI 421 A+ + RE G+ W+G IPT+ +V N + L+ QSK+ + NI Sbjct: 166 ALVRIAREEGVPTLWRGCIPTMARAVVVNAA-------QLASYSQSKQFLLDSGYFSDNI 218 Query: 420 TAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGL 241 F I+ L T + P+ +VK+R+Q + I + Y LD +LK++RYEG Sbjct: 219 LCH--FCASMISGLVTTAASMPVDIVKTRIQNMRMI--DGKPEYKNGLDVLLKVVRYEGF 274 Query: 240 HGFYKG 223 +KG Sbjct: 275 FSLWKG 280 Score = 45.1 bits (105), Expect = 2e-04 Identities = 25/69 (36%), Positives = 40/69 (57%), Gaps = 1/69 (1%) Frame = -3 Query: 405 FLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASR-YTGTLDAILKMIRYEGLHGFY 229 FL G +A +GATV PL +VK+R+Q G A +R Y + A+ +++ EGL G Y Sbjct: 24 FLFGGLAGMGATVFVQPLDLVKNRMQLS---GEGAKTREYKTSFHALTSILKTEGLKGIY 80 Query: 228 KGMGTKIVQ 202 G+ +++ Sbjct: 81 TGLSAGLLR 89
>ADT1_RAT (Q05962) ADP/ATP translocase 1 (Adenine nucleotide translocator 1)| (ANT 1) (ADP,ATP carrier protein 1) (Solute carrier family 25 member 4) Length = 297 Score = 48.5 bits (114), Expect = 2e-05 Identities = 36/154 (23%), Positives = 74/154 (48%), Gaps = 2/154 (1%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGL-IPTLIMVCNPSIQFMIYETLSKRLQSKRSGKRFPKKN 424 G + ++++ G+ G ++G + ++ + F +Y+T L KN Sbjct: 155 GLGDCLTKIFKSDGLKGLYQGFSVSVQGIIIYRAAYFGVYDTAKGMLPDP--------KN 206 Query: 423 ITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAAS-RYTGTLDAILKMIRYE 247 + + +++ A +V+YP V+ R+ + GR A YTGT+D K+ + E Sbjct: 207 VHIIVSWMIAQSVTAVAGLVSYPFDTVRRRMMMQS--GRKGADIMYTGTVDCWRKIAKDE 264 Query: 246 GLHGFYKGMGTKIVQSVFAASVLFMVKEELVKFV 145 G F+KG + +++ + A VL ++ +E+ K+V Sbjct: 265 GRKAFFKGAWSNVLRGMGGAFVL-VLYDEIKKYV 297 Score = 39.7 bits (91), Expect = 0.007 Identities = 35/152 (23%), Positives = 64/152 (42%), Gaps = 8/152 (5%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGLIPTLIMVCNPSIQFMIYETLSKR--LQSKRSGKRFPKK 427 G I + + +E G FW+G + +I ++ K+ L K+F + Sbjct: 52 GIIDCVVRIPKEQGFLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDRHKQFWR- 110 Query: 426 NITAMEVFLLGAIAKLGATVVT-----YPLLVVKSRLQAKQEIGRNAASR-YTGTLDAIL 265 + G +A GA T YPL ++RL A ++G+ ++ R + G D + Sbjct: 111 -------YFAGNLASGGAAGATSLCFVYPLDFARTRLAA--DVGKGSSQREFNGLGDCLT 161 Query: 264 KMIRYEGLHGFYKGMGTKIVQSVFAASVLFMV 169 K+ + +GL G Y+G + + + F V Sbjct: 162 KIFKSDGLKGLYQGFSVSVQGIIIYRAAYFGV 193
>ADT2_BOVIN (Q8SQH5) ADP/ATP translocase 2 (Adenine nucleotide translocator 2)| (ANT 2) (ADP,ATP carrier protein 2) (Solute carrier family 25 member 5) Length = 297 Score = 48.1 bits (113), Expect = 2e-05 Identities = 39/146 (26%), Positives = 66/146 (45%), Gaps = 2/146 (1%) Frame = -3 Query: 579 EVYRESGISGFWKGLIPTLIMVCNPSIQ-FMIYETLSKRLQSKRSGKRFPKKNITAMEVF 403 ++Y+ GI G ++G N S+Q +IY + G KN + Sbjct: 162 KIYKSDGIRGLYQGF--------NVSVQGIIIYRAAYFGIYDTAKGMLPDPKNTHIFISW 213 Query: 402 LLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAAS-RYTGTLDAILKMIRYEGLHGFYK 226 ++ A + +YP V+ R+ + GR YTGTLD K+ R EG F+K Sbjct: 214 MIAQSVTAVAGLTSYPFDTVRRRMMMQS--GRKGTDIMYTGTLDCWRKIARDEGAKAFFK 271 Query: 225 GMGTKIVQSVFAASVLFMVKEELVKF 148 G + +++ + A VL ++ +E+ KF Sbjct: 272 GAWSNVLRGMGGAFVL-VLYDEIKKF 296
>ODC1_YEAST (Q03028) Mitochondrial 2-oxodicarboxylate carrier 1| Length = 310 Score = 47.8 bits (112), Expect = 3e-05 Identities = 27/85 (31%), Positives = 43/85 (50%), Gaps = 8/85 (9%) Frame = -3 Query: 405 FLLGAIAKLGATVVTYPLLVVKSRLQAKQEI--------GRNAASRYTGTLDAILKMIRY 250 F GAIA + +V YPL VVK+R+Q + + A YTG +D + K+++ Sbjct: 15 FTAGAIAGVSELLVMYPLDVVKTRMQLQVTTKGHPAVVAAKAAVDHYTGVMDCLTKIVKK 74 Query: 249 EGLHGFYKGMGTKIVQSVFAASVLF 175 EG YKG+ + I+ ++ F Sbjct: 75 EGFSHLYKGITSPILMEAPKRAIKF 99
>M2OM_BOVIN (P22292) Mitochondrial 2-oxoglutarate/malate carrier protein (OGCP)| (Solute carrier family 25 member 11) Length = 313 Score = 47.8 bits (112), Expect = 3e-05 Identities = 26/69 (37%), Positives = 41/69 (59%), Gaps = 1/69 (1%) Frame = -3 Query: 405 FLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASR-YTGTLDAILKMIRYEGLHGFY 229 FL G +A +GATV PL +VK+R+Q G A +R Y + A++ ++R EGL G Y Sbjct: 24 FLFGGLAGMGATVFVQPLDLVKNRMQLS---GEGAKTREYKTSFHALISILRAEGLRGIY 80 Query: 228 KGMGTKIVQ 202 G+ +++ Sbjct: 81 TGLSAGLLR 89 Score = 46.2 bits (108), Expect = 7e-05 Identities = 36/126 (28%), Positives = 60/126 (47%), Gaps = 4/126 (3%) Frame = -3 Query: 588 AIREVYRESGISGFWKGLIPTLI--MVCNPSIQFMIYETLSKRLQSKRS--GKRFPKKNI 421 A+ + +E G+ W+G IPT+ +V N + L+ QSK+ + NI Sbjct: 166 ALFRIVQEEGVPTLWRGCIPTMARAVVVNAA-------QLASYSQSKQFLLDSGYFSDNI 218 Query: 420 TAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGL 241 F I+ L T + P+ +VK+R+Q + I + Y LD ++K++RYEG Sbjct: 219 LCH--FCASMISGLVTTAASMPVDIVKTRIQNMRMI--DGKPEYKNGLDVLVKVVRYEGF 274 Query: 240 HGFYKG 223 +KG Sbjct: 275 FSLWKG 280
>CMC1_CAEEL (Q21153) Probable calcium-binding mitochondrial carrier K02F3.2| Length = 707 Score = 47.4 bits (111), Expect = 3e-05 Identities = 24/68 (35%), Positives = 40/68 (58%), Gaps = 1/68 (1%) Frame = -3 Query: 405 FLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAAS-RYTGTLDAILKMIRYEGLHGFY 229 FLLG++A YP+ +VK+R+Q ++ G Y +LD K++++EGL G Y Sbjct: 373 FLLGSVAGACGATAVYPIDLVKTRMQNQRTSGSFVGEVMYKNSLDCFKKVVKFEGLLGLY 432 Query: 228 KGMGTKIV 205 +G+ +IV Sbjct: 433 RGLLPQIV 440 Score = 39.3 bits (90), Expect = 0.009 Identities = 37/152 (24%), Positives = 60/152 (39%) Frame = -3 Query: 576 VYRESGISGFWKGLIPTLIMVCNPSIQFMIYETLSKRLQSKRSGKRFPKKNITAMEVFLL 397 V +E G G +KG + S + +K + G P +F Sbjct: 514 VLKELGFLGLYKGSRACFLRDIPFSAIYFPAYAHAKLASADEDGMNSPGT------LFAS 567 Query: 396 GAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFYKGMG 217 IA + A + P V+K+RLQ G+ Y G +D K+I+ EG +KG Sbjct: 568 AFIAGVPAAGLVTPADVIKTRLQVAARAGQTT---YNGVIDCARKLIKEEGPMSLWKGTA 624 Query: 216 TKIVQSVFAASVLFMVKEELVKFVILLVARSR 121 ++ +S +V + E L + + A SR Sbjct: 625 ARVCRSSPQFAVTLLTYEVLQRLFYVDFAGSR 656 Score = 36.2 bits (82), Expect = 0.077 Identities = 31/143 (21%), Positives = 62/143 (43%), Gaps = 2/143 (1%) Frame = -3 Query: 597 TIQAIREVYRESGISGFWKGLIPTLIMVCNPSIQFMIYETLSKRLQSK--RSGKRFPKKN 424 ++ ++V + G+ G ++GL+P ++ V I T++ ++ K + GK Sbjct: 415 SLDCFKKVVKFEGLLGLYRGLLPQIVGVAPEKA---IKLTMNDYMRDKFTKDGK------ 465 Query: 423 ITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEG 244 I + G + V T PL +VK RLQ E+ + G + +++ G Sbjct: 466 IPLYGEIIAGGTGGMCQVVFTNPLEIVKIRLQTAGEV------QQAGKKIGVFTVLKELG 519 Query: 243 LHGFYKGMGTKIVQSVFAASVLF 175 G YKG ++ + +++ F Sbjct: 520 FLGLYKGSRACFLRDIPFSAIYF 542
>CMC1_PONPY (Q5RBC8) Calcium-binding mitochondrial carrier protein Aralar1| (Mitochondrial aspartate glutamate carrier 1) (Solute carrier family 25 member 12) Length = 678 Score = 47.4 bits (111), Expect = 3e-05 Identities = 35/127 (27%), Positives = 61/127 (48%), Gaps = 1/127 (0%) Frame = -3 Query: 576 VYRESGISGFWKGLIPTLIM-VCNPSIQFMIYETLSKRLQSKRSGKRFPKKNITAMEVFL 400 V R+ GI G +KG + + +I F +Y K L + +G ++ + + Sbjct: 471 VLRDLGIFGLYKGAKACFLRDIPFSAIYFPVYAHC-KLLLADENG------HVGGLNLLA 523 Query: 399 LGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFYKGM 220 GA+A + A + P V+K+RLQ G+ Y+G +D K++R EG F+KG Sbjct: 524 AGAMAGVPAASLVTPADVIKTRLQVAARAGQTT---YSGVIDCFRKILREEGPSAFWKGT 580 Query: 219 GTKIVQS 199 ++ +S Sbjct: 581 AARVFRS 587 Score = 44.7 bits (104), Expect = 2e-04 Identities = 37/144 (25%), Positives = 62/144 (43%), Gaps = 1/144 (0%) Frame = -3 Query: 597 TIQAIREVYRESGISGFWKGLIPTLIMVC-NPSIQFMIYETLSKRLQSKRSGKRFPKKNI 421 + ++V R G G ++GLIP LI V +I+ + + + + + P + Sbjct: 372 SFDCFKKVLRYEGFFGLYRGLIPQLIGVAPEKAIKLTVNDFVRDKFTRRDGSVPLPAE-- 429 Query: 420 TAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGL 241 L G A + T PL +VK RLQ EI TG + L ++R G+ Sbjct: 430 -----VLAGGCAGGSQVIFTNPLEIVKIRLQVAGEI-------TTGPRVSALNVLRDLGI 477 Query: 240 HGFYKGMGTKIVQSVFAASVLFMV 169 G YKG ++ + +++ F V Sbjct: 478 FGLYKGAKACFLRDIPFSAIYFPV 501 Score = 44.3 bits (103), Expect = 3e-04 Identities = 25/69 (36%), Positives = 42/69 (60%), Gaps = 2/69 (2%) Frame = -3 Query: 405 FLLGAIA-KLGATVVTYPLLVVKSRLQAKQEIGRNAAS-RYTGTLDAILKMIRYEGLHGF 232 F LG++A +GAT V YP+ +VK+R+Q ++ G Y + D K++RYEG G Sbjct: 330 FTLGSVAGAVGATAV-YPIDLVKTRMQNQRGSGSVVGELMYKNSFDCFKKVLRYEGFFGL 388 Query: 231 YKGMGTKIV 205 Y+G+ +++ Sbjct: 389 YRGLIPQLI 397
>CMC1_HUMAN (O75746) Calcium-binding mitochondrial carrier protein Aralar1| (Mitochondrial aspartate glutamate carrier 1) (Solute carrier family 25 member 12) Length = 678 Score = 47.4 bits (111), Expect = 3e-05 Identities = 35/127 (27%), Positives = 61/127 (48%), Gaps = 1/127 (0%) Frame = -3 Query: 576 VYRESGISGFWKGLIPTLIM-VCNPSIQFMIYETLSKRLQSKRSGKRFPKKNITAMEVFL 400 V R+ GI G +KG + + +I F +Y K L + +G ++ + + Sbjct: 471 VLRDLGIFGLYKGAKACFLRDIPFSAIYFPVYAHC-KLLLADENG------HVGGLNLLA 523 Query: 399 LGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFYKGM 220 GA+A + A + P V+K+RLQ G+ Y+G +D K++R EG F+KG Sbjct: 524 AGAMAGVPAASLVTPADVIKTRLQVAARAGQTT---YSGVIDCFRKILREEGPSAFWKGT 580 Query: 219 GTKIVQS 199 ++ +S Sbjct: 581 AARVFRS 587 Score = 44.7 bits (104), Expect = 2e-04 Identities = 37/144 (25%), Positives = 62/144 (43%), Gaps = 1/144 (0%) Frame = -3 Query: 597 TIQAIREVYRESGISGFWKGLIPTLIMVC-NPSIQFMIYETLSKRLQSKRSGKRFPKKNI 421 + ++V R G G ++GLIP LI V +I+ + + + + + P + Sbjct: 372 SFDCFKKVLRYEGFFGLYRGLIPQLIGVAPEKAIKLTVNDFVRDKFTRRDGSVPLPAE-- 429 Query: 420 TAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGL 241 L G A + T PL +VK RLQ EI TG + L ++R G+ Sbjct: 430 -----VLAGGCAGGSQVIFTNPLEIVKIRLQVAGEI-------TTGPRVSALNVLRDLGI 477 Query: 240 HGFYKGMGTKIVQSVFAASVLFMV 169 G YKG ++ + +++ F V Sbjct: 478 FGLYKGAKACFLRDIPFSAIYFPV 501 Score = 44.3 bits (103), Expect = 3e-04 Identities = 25/69 (36%), Positives = 42/69 (60%), Gaps = 2/69 (2%) Frame = -3 Query: 405 FLLGAIA-KLGATVVTYPLLVVKSRLQAKQEIGRNAAS-RYTGTLDAILKMIRYEGLHGF 232 F LG++A +GAT V YP+ +VK+R+Q ++ G Y + D K++RYEG G Sbjct: 330 FTLGSVAGAVGATAV-YPIDLVKTRMQNQRGSGSVVGELMYKNSFDCFKKVLRYEGFFGL 388 Query: 231 YKGMGTKIV 205 Y+G+ +++ Sbjct: 389 YRGLIPQLI 397
>ADT2_MOUSE (P51881) ADP/ATP translocase 2 (Adenine nucleotide translocator 2)| (ANT 2) (ADP,ATP carrier protein 2) (Solute carrier family 25 member 5) Length = 297 Score = 47.4 bits (111), Expect = 3e-05 Identities = 37/141 (26%), Positives = 61/141 (43%), Gaps = 2/141 (1%) Frame = -3 Query: 579 EVYRESGISGFWKGLIPTLIMVCNPSIQ-FMIYETLSKRLQSKRSGKRFPKKNITAMEVF 403 ++Y+ GI G ++G N S+Q +IY + G KN + Sbjct: 162 KIYKSDGIKGLYQGF--------NVSVQGIIIYRAAYFGIYDTAKGMLPDPKNTHIFISW 213 Query: 402 LLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAAS-RYTGTLDAILKMIRYEGLHGFYK 226 ++ A + +YP V+ R+ + GR YTGTLD K+ R EG F+K Sbjct: 214 MIAQSVTAVAGLTSYPFDTVRRRMMMQS--GRKGTDIMYTGTLDCWRKIARDEGSKAFFK 271 Query: 225 GMGTKIVQSVFAASVLFMVKE 163 G + +++ + A VL + E Sbjct: 272 GAWSNVLRGMGGAFVLVLYDE 292
>ADT2_HUMAN (P05141) ADP/ATP translocase 2 (Adenine nucleotide translocator 2)| (ANT 2) (ADP,ATP carrier protein 2) (Solute carrier family 25 member 5) (ADP,ATP carrier protein, fibroblast isoform) Length = 297 Score = 47.4 bits (111), Expect = 3e-05 Identities = 37/141 (26%), Positives = 62/141 (43%), Gaps = 2/141 (1%) Frame = -3 Query: 579 EVYRESGISGFWKGLIPTLIMVCNPSIQ-FMIYETLSKRLQSKRSGKRFPKKNITAMEVF 403 ++Y+ GI G ++G N S+Q +IY + G KN + + Sbjct: 162 KIYKSDGIKGLYQGF--------NVSVQGIIIYRAAYFGIYDTAKGMLPDPKNTHIVISW 213 Query: 402 LLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAAS-RYTGTLDAILKMIRYEGLHGFYK 226 ++ A + +YP V+ R+ + GR YTGTLD K+ R EG F+K Sbjct: 214 MIAQTVTAVAGLTSYPFDTVRRRMMMQS--GRKGTDIMYTGTLDCWRKIARDEGGKAFFK 271 Query: 225 GMGTKIVQSVFAASVLFMVKE 163 G + +++ + A VL + E Sbjct: 272 GAWSNVLRGMGGAFVLVLYDE 292
>MFRN_DROME (Q9VAY3) Mitoferrin| Length = 379 Score = 47.0 bits (110), Expect = 4e-05 Identities = 40/150 (26%), Positives = 69/150 (46%), Gaps = 2/150 (1%) Frame = -3 Query: 606 PY-GTIQAIREVYRESGISGFWKGLIPTLIM-VCNPSIQFMIYETLSKRLQSKRSGKRFP 433 PY + +R++Y+ G F++ L+M + +I F YE ++ +R K P Sbjct: 141 PYTSVVSCVRDIYKREGFKAFYRAYGTQLVMNLPYQTIHFTTYEFFQNKMNLER--KYNP 198 Query: 432 KKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIR 253 ++ A GA A A VT PL V+K+ L QE G G ++A K+ Sbjct: 199 PVHMAA------GAAAGACAAAVTTPLDVIKTLLNT-QETGLT-----RGMIEASRKIYH 246 Query: 252 YEGLHGFYKGMGTKIVQSVFAASVLFMVKE 163 G GF++G +++ S+ A ++ + E Sbjct: 247 MAGPLGFFRGTTARVLYSMPATAICWSTYE 276 Score = 38.5 bits (88), Expect = 0.016 Identities = 29/114 (25%), Positives = 52/114 (45%) Frame = -3 Query: 504 SIQFMIYETLSKRLQSKRSGKRFPKKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQA 325 S+ F YE ++K L +K + R + + GA+A L ++ P V+K R+Q Sbjct: 86 SLYFAAYE-MTKELTAKFTSVR-------NLNYVISGAVATLIHDAISSPTDVIKQRMQM 137 Query: 324 KQEIGRNAASRYTGTLDAILKMIRYEGLHGFYKGMGTKIVQSVFAASVLFMVKE 163 S YT + + + + EG FY+ GT++V ++ ++ F E Sbjct: 138 YN-------SPYTSVVSCVRDIYKREGFKAFYRAYGTQLVMNLPYQTIHFTTYE 184 Score = 29.6 bits (65), Expect = 7.2 Identities = 28/87 (32%), Positives = 40/87 (45%), Gaps = 4/87 (4%) Frame = -3 Query: 396 GAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFYKGMG 217 GAIA + VV YPL VK+R+Q+ +N + + MI EGL +G Sbjct: 21 GAIAGVLEHVVMYPLDSVKTRMQSLSPPTKN-----MNIVSTLRTMITREGLLRPIRGAS 75 Query: 216 TKIVQSVFAASVLF----MVKEELVKF 148 ++ + A S+ F M KE KF Sbjct: 76 AVVLGAGPAHSLYFAAYEMTKELTAKF 102
>ORNT1_HUMAN (Q9Y619) Mitochondrial ornithine transporter 1 (Solute carrier| family 25 member 15) Length = 301 Score = 46.6 bits (109), Expect = 6e-05 Identities = 36/143 (25%), Positives = 63/143 (44%), Gaps = 2/143 (1%) Frame = -3 Query: 585 IREVYRESGISGFWKGLIPTLIMVCNPSIQFMI--YETLSKRLQSKRSGKRFPKKNITAM 412 I+ + R+ G GF+ GL TL+ P F YE S RS K + + Sbjct: 157 IKSILRKDGPLGFYHGLSSTLLREV-PGYFFFFGGYELSRSFFASGRS-----KDELGPV 210 Query: 411 EVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGF 232 + L G + + + YP+ +KSR+Q G+ A G + + +++ EG+ Sbjct: 211 PLMLSGGVGGICLWLAVYPVDCIKSRIQVLSMSGKQA-----GFIRTFINVVKNEGITAL 265 Query: 231 YKGMGTKIVQSVFAASVLFMVKE 163 Y G+ ++++ A LF+ E Sbjct: 266 YSGLKPTMIRAFPANGALFLAYE 288 Score = 35.0 bits (79), Expect = 0.17 Identities = 21/75 (28%), Positives = 31/75 (41%) Frame = -3 Query: 396 GAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFYKGMG 217 GA + P +K ++Q ++ Y G D LK G GFYKG Sbjct: 16 GAAGGTACVLTGQPFDTMKVKMQTFPDL-------YRGLTDCCLKTYSQVGFRGFYKGTS 68 Query: 216 TKIVQSVFAASVLFM 172 ++ ++ SVLFM Sbjct: 69 PALIANIAENSVLFM 83
>M2OM_RAT (P97700) Mitochondrial 2-oxoglutarate/malate carrier protein (OGCP)| (Solute carrier family 25 member 11) Length = 313 Score = 46.6 bits (109), Expect = 6e-05 Identities = 38/126 (30%), Positives = 59/126 (46%), Gaps = 4/126 (3%) Frame = -3 Query: 588 AIREVYRESGISGFWKGLIPTLI--MVCNPSIQFMIYETLSKRLQSKRS--GKRFPKKNI 421 A+ + RE G+ W+G IPT+ +V N + L+ QSK+ + NI Sbjct: 166 ALIRIAREEGVPTLWRGCIPTMARAVVVNAA-------QLASYSQSKQFLLDSGYFSDNI 218 Query: 420 TAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGL 241 F I+ L T + P+ +VK+R+Q + I Y LD +LK++RYEG Sbjct: 219 LCH--FCAIMISGLVTTAASMPVDIVKTRIQNMRMIDEKP--EYKNGLDVLLKVVRYEGF 274 Query: 240 HGFYKG 223 +KG Sbjct: 275 FSLWKG 280 Score = 43.1 bits (100), Expect = 6e-04 Identities = 24/69 (34%), Positives = 39/69 (56%), Gaps = 1/69 (1%) Frame = -3 Query: 405 FLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASR-YTGTLDAILKMIRYEGLHGFY 229 FL G +A +GATV PL +V +R+Q G A +R Y + A+ +++ EGL G Y Sbjct: 24 FLFGGLAGMGATVFVQPLDLVXNRMQLS---GEGAKTREYKTSFHALTSILKAEGLRGIY 80 Query: 228 KGMGTKIVQ 202 G+ +++ Sbjct: 81 TGLSAGLLR 89
>ADT2_RAT (Q09073) ADP/ATP translocase 2 (Adenine nucleotide translocator 2)| (ANT 2) (ADP,ATP carrier protein 2) (Solute carrier family 25 member 5) Length = 297 Score = 46.6 bits (109), Expect = 6e-05 Identities = 37/141 (26%), Positives = 61/141 (43%), Gaps = 2/141 (1%) Frame = -3 Query: 579 EVYRESGISGFWKGLIPTLIMVCNPSIQ-FMIYETLSKRLQSKRSGKRFPKKNITAMEVF 403 ++Y+ GI G ++G N S+Q +IY + G KN + Sbjct: 162 KIYKSDGIKGLYQGF--------NVSVQGIIIYRAAYFGIYDTAKGMLPDPKNTHIFISW 213 Query: 402 LLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAAS-RYTGTLDAILKMIRYEGLHGFYK 226 ++ A + +YP V+ R+ + GR YTGTLD K+ R EG F+K Sbjct: 214 MIAQSVTAVAGLTSYPFDTVRRRMMMQS--GRKGTDIMYTGTLDCWRKIARDEGGKAFFK 271 Query: 225 GMGTKIVQSVFAASVLFMVKE 163 G + +++ + A VL + E Sbjct: 272 GAWSNVLRGMGGAFVLVLYDE 292
>UCP2_CYPCA (Q9W725) Mitochondrial uncoupling protein 2 (UCP 2)| Length = 310 Score = 46.2 bits (108), Expect = 7e-05 Identities = 40/155 (25%), Positives = 69/155 (44%), Gaps = 1/155 (0%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGLIPTLIMVCN-PSIQFMIYETLSKRLQSKRSGKRFPKKN 424 G I + R G + GL+ L + S++ +Y+++ K+ +K S ++ Sbjct: 62 GVFGTISTMVRVEGPRSLYSGLVAGLQRQMSFASVRIGLYDSV-KQFYTKGS------EH 114 Query: 423 ITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEG 244 + + G A + P VVK R QA+ G N RY GT+DA + + EG Sbjct: 115 VGIGSRLMAGCTTGAMAVALAQPTDVVKVRFQAQNSAGAN--KRYHGTMDAYRTIAKEEG 172 Query: 243 LHGFYKGMGTKIVQSVFAASVLFMVKEELVKFVIL 139 G +KG G I ++ + +V +L+K +L Sbjct: 173 FRGLWKGTGPNITRNAI-VNCTELVTYDLIKDALL 206 Score = 45.1 bits (105), Expect = 2e-04 Identities = 42/156 (26%), Positives = 67/156 (42%), Gaps = 5/156 (3%) Frame = -3 Query: 609 RPYGTIQAIREVYRESGISGFWKGLIPTL----IMVCNPSIQF-MIYETLSKRLQSKRSG 445 R +GT+ A R + +E G G WKG P + I+ C + + +I + L L+S Sbjct: 156 RYHGTMDAYRTIAKEEGFRGLWKGTGPNITRNAIVNCTELVTYDLIKDAL---LKSSLMT 212 Query: 444 KRFPKKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAIL 265 P +A A TV+ P+ VVK+R +A +Y L+ + Sbjct: 213 DDLPCHFTSAFG-------AGFCTTVIASPVDVVKTRYM------NSAPGQYCSALNCAV 259 Query: 264 KMIRYEGLHGFYKGMGTKIVQSVFAASVLFMVKEEL 157 M+ EG FYKG ++ V+F+ E+L Sbjct: 260 AMLTKEGPKAFYKGFMPSFLRLGSWNVVMFVTYEQL 295 Score = 33.9 bits (76), Expect = 0.38 Identities = 28/96 (29%), Positives = 42/96 (43%), Gaps = 5/96 (5%) Frame = -3 Query: 420 TAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQE--IGRNAAS---RYTGTLDAILKMI 256 TA F+ A A + T+PL K RLQ + E I N +Y G I M+ Sbjct: 12 TATVKFIGAGTAACIADLFTFPLDTAKVRLQIQGESKIPVNTGHGPVKYRGVFGTISTMV 71 Query: 255 RYEGLHGFYKGMGTKIVQSVFAASVLFMVKEELVKF 148 R EG Y G+ + + + ASV + + + +F Sbjct: 72 RVEGPRSLYSGLVAGLQRQMSFASVRIGLYDSVKQF 107
>YMC1_YEAST (P32331) Carrier protein YMC1, mitochondrial precursor| Length = 307 Score = 45.8 bits (107), Expect = 1e-04 Identities = 40/151 (26%), Positives = 72/151 (47%), Gaps = 5/151 (3%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGLIPTLIMVCNP-SIQFMIYETLSKRLQSKRSGKRFPKKN 424 G ++ I+++ + +GL PT++ + F++YE L +KR G +K+ Sbjct: 162 GPLECIKKLRHNKALL---RGLTPTILREGHGCGTYFLVYEALIANQMNKRRG--LERKD 216 Query: 423 ITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQA----KQEIGRNAASRYTGTLDAILKMI 256 I A ++ + GA++ ++ YPL V+KS +Q K + G N+ S TL A Sbjct: 217 IPAWKLCIFGALSGTALWLMVYPLDVIKSVMQTDNLQKPKFG-NSISSVAKTLYA----- 270 Query: 255 RYEGLHGFYKGMGTKIVQSVFAASVLFMVKE 163 G+ F+KG G ++++ A F E Sbjct: 271 -NGGIGAFFKGFGPTMLRAAPANGATFATFE 300 Score = 36.6 bits (83), Expect = 0.059 Identities = 25/93 (26%), Positives = 40/93 (43%) Frame = -3 Query: 426 NITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYE 247 N ++ L G + +V P K RLQ +S T ++ + K++ E Sbjct: 22 NARVVKDLLAGTAGGIAQVLVGQPFDTTKVRLQT--------SSTPTTAMEVVRKLLANE 73 Query: 246 GLHGFYKGMGTKIVQSVFAASVLFMVKEELVKF 148 G GFYKG T ++ S+ F V E + +F Sbjct: 74 GPRGFYKGTLTPLIGVGACVSLQFGVNEAMKRF 106
>CMC2_HUMAN (Q9UJS0) Calcium-binding mitochondrial carrier protein Aralar2| (Mitochondrial aspartate glutamate carrier 2) (Solute carrier family 25 member 13) (Citrin) Length = 675 Score = 45.8 bits (107), Expect = 1e-04 Identities = 36/144 (25%), Positives = 63/144 (43%), Gaps = 1/144 (0%) Frame = -3 Query: 576 VYRESGISGFWKGLIPTLIM-VCNPSIQFMIYETLSKRLQSKRSGKRFPKKNITAMEVFL 400 V R+ G G +KG + + +I F Y + ++ ++ + L Sbjct: 473 VVRDLGFFGIYKGAKACFLRDIPFSAIYFPCYAHVKASFANEDG-------QVSPGSLLL 525 Query: 399 LGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFYKGM 220 GAIA + A + P V+K+RLQ G+ Y+G +D K++R EG +KG Sbjct: 526 AGAIAGMPAASLVTPADVIKTRLQVAARAGQTT---YSGVIDCFRKILREEGPKALWKGA 582 Query: 219 GTKIVQSVFAASVLFMVKEELVKF 148 G ++ +S V + E L ++ Sbjct: 583 GARVFRSSPQFGVTLLTYELLQRW 606 Score = 43.9 bits (102), Expect = 4e-04 Identities = 25/64 (39%), Positives = 39/64 (60%), Gaps = 2/64 (3%) Frame = -3 Query: 405 FLLGAIA-KLGATVVTYPLLVVKSRLQAKQEIGRNAAS-RYTGTLDAILKMIRYEGLHGF 232 F LG++A +GAT V YP+ +VK+R+Q ++ G Y + D K++RYEG G Sbjct: 332 FGLGSVAGAVGATAV-YPIDLVKTRMQNQRSTGSFVGELMYKNSFDCFKKVLRYEGFFGL 390 Query: 231 YKGM 220 Y+G+ Sbjct: 391 YRGL 394 Score = 42.0 bits (97), Expect = 0.001 Identities = 34/142 (23%), Positives = 60/142 (42%), Gaps = 1/142 (0%) Frame = -3 Query: 597 TIQAIREVYRESGISGFWKGLIPTLIMVC-NPSIQFMIYETLSKRLQSKRSGKRFPKKNI 421 + ++V R G G ++GL+P L+ V +I+ + + + + K ++ Sbjct: 374 SFDCFKKVLRYEGFFGLYRGLLPQLLGVAPEKAIKLTVNDFVRDKFMHKDG-------SV 426 Query: 420 TAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGL 241 L G A + T PL +VK RLQ EI TG + L ++R G Sbjct: 427 PLAAEILAGGCAGGSQVIFTNPLEIVKIRLQVAGEI-------TTGPRVSALSVVRDLGF 479 Query: 240 HGFYKGMGTKIVQSVFAASVLF 175 G YKG ++ + +++ F Sbjct: 480 FGIYKGAKACFLRDIPFSAIYF 501
>ADT3_HUMAN (P12236) ADP/ATP translocase 3 (Adenine nucleotide translocator 2)| (ANT 3) (ADP,ATP carrier protein 3) (Solute carrier family 25 member 6) (ADP,ATP carrier protein, isoform T2) Length = 297 Score = 45.8 bits (107), Expect = 1e-04 Identities = 36/141 (25%), Positives = 64/141 (45%), Gaps = 2/141 (1%) Frame = -3 Query: 579 EVYRESGISGFWKGL-IPTLIMVCNPSIQFMIYETLSKRLQSKRSGKRFPKKNITAMEVF 403 ++ + GI G ++G + ++ + F +Y+T L KN + + Sbjct: 162 KITKSDGIRGLYQGFSVSVQGIIIYRAAYFGVYDTAKGMLPDP--------KNTHIVVSW 213 Query: 402 LLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAAS-RYTGTLDAILKMIRYEGLHGFYK 226 ++ A VV+YP V+ R+ + GR A YTGT+D K+ R EG F+K Sbjct: 214 MIAQTVTAVAGVVSYPFDTVRRRMMMQS--GRKGADIMYTGTVDCWRKIFRDEGGKAFFK 271 Query: 225 GMGTKIVQSVFAASVLFMVKE 163 G + +++ + A VL + E Sbjct: 272 GAWSNVLRGMGGAFVLVLYDE 292
>ADT2_PONPY (Q5R5A1) ADP/ATP translocase 2 (Adenine nucleotide translocator 2)| (ANT 2) (ADP,ATP carrier protein 2) (Solute carrier family 25 member 5) Length = 297 Score = 45.8 bits (107), Expect = 1e-04 Identities = 36/141 (25%), Positives = 61/141 (43%), Gaps = 2/141 (1%) Frame = -3 Query: 579 EVYRESGISGFWKGLIPTLIMVCNPSIQ-FMIYETLSKRLQSKRSGKRFPKKNITAMEVF 403 ++Y+ GI G ++G N S+Q +IY + G KN + + Sbjct: 162 KIYKSDGIKGLYQGF--------NVSVQGIIIYRAAYFGIYDTAKGMLPDPKNTHIVISW 213 Query: 402 LLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAAS-RYTGTLDAILKMIRYEGLHGFYK 226 ++ A + +YP V+ R+ + GR YTGTLD K+ R EG F+K Sbjct: 214 MIAQTVTAVAGLTSYPFDTVRRRMMMQS--GRKGTDIMYTGTLDCWRKIARDEGGKAFFK 271 Query: 225 GMGTKIVQSVFAASVLFMVKE 163 G + +++ + A L + E Sbjct: 272 GAWSNVLRGMGGAFALVLYDE 292
>M2OM_HUMAN (Q02978) Mitochondrial 2-oxoglutarate/malate carrier protein (OGCP)| (Solute carrier family 25 member 11) Length = 313 Score = 45.4 bits (106), Expect = 1e-04 Identities = 25/69 (36%), Positives = 40/69 (57%), Gaps = 1/69 (1%) Frame = -3 Query: 405 FLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASR-YTGTLDAILKMIRYEGLHGFY 229 FL G +A +GATV PL +VK+R+Q G A +R Y + A+ +++ EGL G Y Sbjct: 24 FLFGGLAGMGATVFVQPLDLVKNRMQLS---GEGAKTREYKTSFHALTSILKAEGLRGIY 80 Query: 228 KGMGTKIVQ 202 G+ +++ Sbjct: 81 TGLSAGLLR 89 Score = 45.1 bits (105), Expect = 2e-04 Identities = 36/126 (28%), Positives = 58/126 (46%), Gaps = 4/126 (3%) Frame = -3 Query: 588 AIREVYRESGISGFWKGLIPTLI--MVCNPSIQFMIYETLSKRLQSKRS--GKRFPKKNI 421 A+ + RE G+ W+G IPT+ +V N + L+ QSK+ + NI Sbjct: 166 ALIRITREEGVLTLWRGCIPTMARAVVVNAA-------QLASYSQSKQFLLDSGYFSDNI 218 Query: 420 TAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGL 241 F I+ L T + P+ + K+R+Q + I + Y LD + K++RYEG Sbjct: 219 LCH--FCASMISGLVTTAASMPVDIAKTRIQNMRMI--DGKPEYKNGLDVLFKVVRYEGF 274 Query: 240 HGFYKG 223 +KG Sbjct: 275 FSLWKG 280
>CMC1_MOUSE (Q8BH59) Calcium-binding mitochondrial carrier protein Aralar1| (Mitochondrial aspartate glutamate carrier 1) (Solute carrier family 25 member 12) Length = 677 Score = 45.4 bits (106), Expect = 1e-04 Identities = 39/143 (27%), Positives = 60/143 (41%) Frame = -3 Query: 597 TIQAIREVYRESGISGFWKGLIPTLIMVCNPSIQFMIYETLSKRLQSKRSGKRFPKKNIT 418 + ++V R G G ++GLIP LI V + + +KR G +I Sbjct: 372 SFDCFKKVLRYEGFFGLYRGLIPQLIGVAPEKAIKLTVNDFVRDKFTKRDG------SIP 425 Query: 417 AMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLH 238 L G A + T PL +VK RLQ EI TG + L +++ GL Sbjct: 426 LPAEILAGGCAGGSQVIFTNPLEIVKIRLQVAGEI-------TTGPRVSALNVLQDLGLF 478 Query: 237 GFYKGMGTKIVQSVFAASVLFMV 169 G YKG ++ + +++ F V Sbjct: 479 GLYKGAKACFLRDIPFSAIYFPV 501 Score = 45.1 bits (105), Expect = 2e-04 Identities = 33/127 (25%), Positives = 61/127 (48%), Gaps = 1/127 (0%) Frame = -3 Query: 576 VYRESGISGFWKGLIPTLIM-VCNPSIQFMIYETLSKRLQSKRSGKRFPKKNITAMEVFL 400 V ++ G+ G +KG + + +I F +Y K L + +G+ + + + Sbjct: 471 VLQDLGLFGLYKGAKACFLRDIPFSAIYFPVYAHC-KLLLADENGR------VGGINLLT 523 Query: 399 LGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFYKGM 220 GA+A + A + P V+K+RLQ G+ Y+G +D K++R EG F+KG Sbjct: 524 AGALAGVPAASLVTPADVIKTRLQVAARAGQTT---YSGVVDCFRKILREEGPSAFWKGT 580 Query: 219 GTKIVQS 199 ++ +S Sbjct: 581 AARVFRS 587 Score = 44.7 bits (104), Expect = 2e-04 Identities = 25/69 (36%), Positives = 42/69 (60%), Gaps = 2/69 (2%) Frame = -3 Query: 405 FLLGAIA-KLGATVVTYPLLVVKSRLQAKQEIGRNAAS-RYTGTLDAILKMIRYEGLHGF 232 F LG++A +GAT V YP+ +VK+R+Q ++ G Y + D K++RYEG G Sbjct: 330 FTLGSVAGAVGATAV-YPIDLVKTRMQNQRGTGSVVGELMYKNSFDCFKKVLRYEGFFGL 388 Query: 231 YKGMGTKIV 205 Y+G+ +++ Sbjct: 389 YRGLIPQLI 397
>UCP2_RAT (P56500) Mitochondrial uncoupling protein 2 (UCP 2)| Length = 309 Score = 45.4 bits (106), Expect = 1e-04 Identities = 43/159 (27%), Positives = 67/159 (42%), Gaps = 8/159 (5%) Frame = -3 Query: 609 RPYGTIQAIREVYRESGISGFWKGLIPTL----IMVCNPSIQF-MIYETLSKRLQSKRSG 445 R T++A + + RE GI G WKG P + I+ C + + +I +TL K Sbjct: 155 RYQSTVEAYKTIAREEGIRGLWKGTSPNVARNAIVNCTELVTYDLIKDTLLKA------- 207 Query: 444 KRFPKKNITAMEV---FLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLD 274 N+ ++ F A TV+ P+ VVK+R +A +Y Sbjct: 208 ------NLMTDDLPCHFTSAFGAGFCTTVIASPVDVVKTRYM------NSALGQYHSAGH 255 Query: 273 AILKMIRYEGLHGFYKGMGTKIVQSVFAASVLFMVKEEL 157 L M+R EG FYKG ++ V+F+ E+L Sbjct: 256 CALTMLRKEGPRAFYKGFMPSFLRLGSWNVVMFVTYEQL 294 Score = 45.4 bits (106), Expect = 1e-04 Identities = 33/95 (34%), Positives = 48/95 (50%), Gaps = 4/95 (4%) Frame = -3 Query: 420 TAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQE---IGRNAAS-RYTGTLDAILKMIR 253 TA FL A A ++T+PL K RLQ + E + R AAS +Y G L IL M+R Sbjct: 12 TATVKFLGAGTAACIADLITFPLDTAKVRLQIQGESQGLARTAASAQYRGVLGTILTMVR 71 Query: 252 YEGLHGFYKGMGTKIVQSVFAASVLFMVKEELVKF 148 EG Y G+ + + + ASV + + + +F Sbjct: 72 TEGPRSLYNGLVAGLQRQMSFASVRIGLYDSVKQF 106 Score = 40.0 bits (92), Expect = 0.005 Identities = 38/155 (24%), Positives = 68/155 (43%), Gaps = 1/155 (0%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGLIPTLIMVCN-PSIQFMIYETLSKRLQSKRSGKRFPKKN 424 G + I + R G + GL+ L + S++ +Y+++ K+ +K S ++ Sbjct: 61 GVLGTILTMVRTEGPRSLYNGLVAGLQRQMSFASVRIGLYDSV-KQFYTKGS------EH 113 Query: 423 ITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEG 244 L G+ A V P VVK R QA+ G RY T++A + R EG Sbjct: 114 AGIGSRLLAGSTTGALAVAVAQPTDVVKVRFQAQARAG--GGRRYQSTVEAYKTIAREEG 171 Query: 243 LHGFYKGMGTKIVQSVFAASVLFMVKEELVKFVIL 139 + G +KG + ++ + +V +L+K +L Sbjct: 172 IRGLWKGTSPNVARNAI-VNCTELVTYDLIKDTLL 205
>UCP2_MOUSE (P70406) Mitochondrial uncoupling protein 2 (UCP 2) (UCPH)| Length = 309 Score = 45.1 bits (105), Expect = 2e-04 Identities = 46/171 (26%), Positives = 73/171 (42%), Gaps = 8/171 (4%) Frame = -3 Query: 609 RPYGTIQAIREVYRESGISGFWKGLIPTL----IMVCNPSIQF-MIYETLSKRLQSKRSG 445 R T++A + + RE GI G WKG P + I+ C + + +I +TL K Sbjct: 155 RYQSTVEAYKTIAREEGIRGLWKGTSPNVARNAIVNCAELVTYDLIKDTLLKA------- 207 Query: 444 KRFPKKNITAMEV---FLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLD 274 N+ ++ F A TV+ P+ VVK+R +A +Y Sbjct: 208 ------NLMTDDLPCHFTSAFGAGFCTTVIASPVDVVKTRYM------NSALGQYHSAGH 255 Query: 273 AILKMIRYEGLHGFYKGMGTKIVQSVFAASVLFMVKEELVKFVILLVARSR 121 L M+R EG FYKG ++ V+F+ E+L K ++ +SR Sbjct: 256 CALTMLRKEGPRAFYKGFMPSFLRLGSWNVVMFVTYEQL-KRALMAAYQSR 305 Score = 44.3 bits (103), Expect = 3e-04 Identities = 33/95 (34%), Positives = 48/95 (50%), Gaps = 4/95 (4%) Frame = -3 Query: 420 TAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQE---IGRNAAS-RYTGTLDAILKMIR 253 TA FL A A ++T+PL K RLQ + E + R AAS +Y G L IL M+R Sbjct: 12 TATVKFLGAGTAACIADLITFPLDTAKVRLQIQGESQGLVRTAASAQYRGVLGTILTMVR 71 Query: 252 YEGLHGFYKGMGTKIVQSVFAASVLFMVKEELVKF 148 EG Y G+ + + + ASV + + + +F Sbjct: 72 TEGPRSLYNGLVAGLQRQMSFASVRIGLYDSVKQF 106 Score = 40.0 bits (92), Expect = 0.005 Identities = 38/155 (24%), Positives = 68/155 (43%), Gaps = 1/155 (0%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGLIPTLIMVCN-PSIQFMIYETLSKRLQSKRSGKRFPKKN 424 G + I + R G + GL+ L + S++ +Y+++ K+ +K S ++ Sbjct: 61 GVLGTILTMVRTEGPRSLYNGLVAGLQRQMSFASVRIGLYDSV-KQFYTKGS------EH 113 Query: 423 ITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEG 244 L G+ A V P VVK R QA+ G RY T++A + R EG Sbjct: 114 AGIGSRLLAGSTTGALAVAVAQPTDVVKVRFQAQARAG--GGRRYQSTVEAYKTIAREEG 171 Query: 243 LHGFYKGMGTKIVQSVFAASVLFMVKEELVKFVIL 139 + G +KG + ++ + +V +L+K +L Sbjct: 172 IRGLWKGTSPNVARNAI-VNCAELVTYDLIKDTLL 205
>CG69_HUMAN (Q9BZJ4) Mitochondrial carrier protein CGI-69| Length = 359 Score = 44.7 bits (104), Expect = 2e-04 Identities = 39/150 (26%), Positives = 64/150 (42%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGLIPTLIMVCNPSIQFMIYETLSKRLQSKRSGKRFPKKNI 421 GT+ A ++ R G W GL TL+M + IY T +L++ G+ Sbjct: 106 GTMDAFVKIVRHEGTRTLWSGLPATLVMTVPATA---IYFTAYDQLKAFLCGRALTSDLY 162 Query: 420 TAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGL 241 M + GA+A+LG V PL +++++LQA+ R + + + G Sbjct: 163 APM---VAGALARLGTVTVISPLELMRTKLQAQHVSYRELGA-------CVRTAVAQGGW 212 Query: 240 HGFYKGMGTKIVQSVFAASVLFMVKEELVK 151 + G G ++ V S L+ ELVK Sbjct: 213 RSLWLGWGPTALRDV-PFSALYWFNYELVK 241 Score = 42.4 bits (98), Expect = 0.001 Identities = 17/51 (33%), Positives = 33/51 (64%) Frame = -3 Query: 297 SRYTGTLDAILKMIRYEGLHGFYKGMGTKIVQSVFAASVLFMVKEELVKFV 145 +R+TGT+DA +K++R+EG + G+ +V +V A ++ F ++L F+ Sbjct: 102 TRFTGTMDAFVKIVRHEGTRTLWSGLPATLVMTVPATAIYFTAYDQLKAFL 152
>ADT2_ANOGA (Q7PQV7) ADP,ATP carrier protein 2 (ADP/ATP translocase 2) (Adenine| nucleotide translocator 2) (ANT 2) Length = 300 Score = 44.7 bits (104), Expect = 2e-04 Identities = 35/137 (25%), Positives = 59/137 (43%), Gaps = 6/137 (4%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGLIPTLIMVCNPSIQFMIYETLSKRLQSKRSGKRFPKKNI 421 G + + RE G S FW+G + +I ++ K++ K Sbjct: 55 GMVDCFVRIPREQGFSAFWRGNLANVIRYFPTQALNFAFKDKYKQVFLGGVDKN------ 108 Query: 420 TAMEVFLLGAIAKLGATVVT-----YPLLVVKSRLQAKQEIGRNAASR-YTGTLDAILKM 259 T + +G +A G T YPL ++RL A ++G+ A +R + G D I K+ Sbjct: 109 TQFTRYFIGNLASGGMAGATSLCFVYPLDFARTRLAA--DVGKGAEAREFKGLGDCISKI 166 Query: 258 IRYEGLHGFYKGMGTKI 208 + +GL G Y+G G + Sbjct: 167 FKTDGLVGLYRGFGVSV 183 Score = 35.0 bits (79), Expect = 0.17 Identities = 33/152 (21%), Positives = 63/152 (41%), Gaps = 6/152 (3%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGL-IPTLIMVCNPSIQFMIYETLSKRLQSKRSGKRFPKKN 424 G I ++++ G+ G ++G + ++ + F Y+T L + ++ + Sbjct: 158 GLGDCISKIFKTDGLVGLYRGFGVSVQGIIIYRAAYFGFYDTARGMLPNPKTTPWYVSWA 217 Query: 423 ITAMEVFLLGAIAKLGATVVTYPLLVVKSRL-----QAKQEIGRNAASRYTGTLDAILKM 259 I + G +V+YP V+ R+ +AK EI Y GTL + Sbjct: 218 IAQCVTTVAG--------IVSYPFDTVRRRMMMQSGRAKSEIV------YKGTLHCWATI 263 Query: 258 IRYEGLHGFYKGMGTKIVQSVFAASVLFMVKE 163 + EG F+KG + +++ A VL + E Sbjct: 264 AKQEGTGAFFKGAFSNVLRGTGGAFVLVLYDE 295
>ADT3_BOVIN (P32007) ADP/ATP translocase 3 (Adenine nucleotide translocator 2)| (ANT 3) (ADP,ATP carrier protein 3) (Solute carrier family 25 member 6) (ADP,ATP carrier protein, isoform T2) (ANT 2) Length = 297 Score = 44.7 bits (104), Expect = 2e-04 Identities = 36/141 (25%), Positives = 63/141 (44%), Gaps = 2/141 (1%) Frame = -3 Query: 579 EVYRESGISGFWKGLIPTLIMVCNPSIQ-FMIYETLSKRLQSKRSGKRFPKKNITAMEVF 403 ++ + GI G ++G N S+Q +IY + G KN + + Sbjct: 162 KITKSDGIRGLYQGF--------NVSVQGIIIYRAAYFGIYDTAKGMLPDPKNTHIVVSW 213 Query: 402 LLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAAS-RYTGTLDAILKMIRYEGLHGFYK 226 ++ A VV+YP V+ R+ + GR A Y GT+D K+++ EG F+K Sbjct: 214 MIAQTVTAVAGVVSYPFDTVRRRMMMQS--GRKGADIMYKGTVDCWRKILKDEGGKAFFK 271 Query: 225 GMGTKIVQSVFAASVLFMVKE 163 G + +++ + A VL + E Sbjct: 272 GAWSNVLRGMGGAFVLVLYDE 292
>CMC2_MOUSE (Q9QXX4) Calcium-binding mitochondrial carrier protein Aralar2| (Mitochondrial aspartate glutamate carrier 2) (Solute carrier family 25 member 13) (Citrin) Length = 676 Score = 44.3 bits (103), Expect = 3e-04 Identities = 26/64 (40%), Positives = 39/64 (60%), Gaps = 2/64 (3%) Frame = -3 Query: 405 FLLGAIA-KLGATVVTYPLLVVKSRLQAKQEIGRNAAS-RYTGTLDAILKMIRYEGLHGF 232 F LG+IA +GAT V YP+ +VK+R+Q ++ G Y + D K++RYEG G Sbjct: 333 FGLGSIAGAVGATAV-YPIDLVKTRMQNQRSTGSFVGELMYKNSFDCFKKVLRYEGFFGL 391 Query: 231 YKGM 220 Y+G+ Sbjct: 392 YRGL 395 Score = 42.7 bits (99), Expect = 8e-04 Identities = 35/144 (24%), Positives = 61/144 (42%), Gaps = 1/144 (0%) Frame = -3 Query: 576 VYRESGISGFWKGLIPTLIM-VCNPSIQFMIYETLSKRLQSKRSGKRFPKKNITAMEVFL 400 V R+ G G +KG + + +I F Y + ++ ++ + L Sbjct: 474 VVRDLGFFGIYKGAKACFLRDIPFSAIYFPCYAHVKASFANEDG-------QVSPGSLLL 526 Query: 399 LGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFYKGM 220 GAIA + A + P V+K+RLQ G+ Y G D K++R EG +KG+ Sbjct: 527 AGAIAGMPAASLVTPADVIKTRLQVAARAGQTT---YNGVTDCFRKILREEGPKALWKGV 583 Query: 219 GTKIVQSVFAASVLFMVKEELVKF 148 ++ +S V + E L ++ Sbjct: 584 AARVFRSSPQFGVTLLTYELLQRW 607 Score = 41.6 bits (96), Expect = 0.002 Identities = 33/142 (23%), Positives = 60/142 (42%), Gaps = 1/142 (0%) Frame = -3 Query: 597 TIQAIREVYRESGISGFWKGLIPTLIMVC-NPSIQFMIYETLSKRLQSKRSGKRFPKKNI 421 + ++V R G G ++GL+P L+ V +I+ + + + + K ++ Sbjct: 375 SFDCFKKVLRYEGFFGLYRGLLPQLLGVAPEKAIKLTVNDFVRDKFMHKDG-------SV 427 Query: 420 TAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGL 241 + G A + T PL +VK RLQ EI TG + L ++R G Sbjct: 428 PLLAEIFAGGCAGGSQVIFTNPLEIVKIRLQVAGEI-------TTGPRVSALSVVRDLGF 480 Query: 240 HGFYKGMGTKIVQSVFAASVLF 175 G YKG ++ + +++ F Sbjct: 481 FGIYKGAKACFLRDIPFSAIYF 502
>UCP2_HUMAN (P55851) Mitochondrial uncoupling protein 2 (UCP 2) (UCPH)| Length = 309 Score = 43.9 bits (102), Expect = 4e-04 Identities = 29/95 (30%), Positives = 47/95 (49%), Gaps = 4/95 (4%) Frame = -3 Query: 420 TAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQE----IGRNAASRYTGTLDAILKMIR 253 TA FL A A ++T+PL K RLQ + E + A+++Y G + IL M+R Sbjct: 12 TATVKFLGAGTAACIADLITFPLDTAKVRLQIQGESQGPVRATASAQYRGVMGTILTMVR 71 Query: 252 YEGLHGFYKGMGTKIVQSVFAASVLFMVKEELVKF 148 EG Y G+ + + + ASV + + + +F Sbjct: 72 TEGPRSLYNGLVAGLQRQMSFASVRIGLYDSVKQF 106
>DIC_HUMAN (Q9UBX3) Mitochondrial dicarboxylate carrier (Solute carrier family| 25 member 10) Length = 287 Score = 43.9 bits (102), Expect = 4e-04 Identities = 33/119 (27%), Positives = 52/119 (43%), Gaps = 1/119 (0%) Frame = -3 Query: 576 VYRESGISGFWKGLIPTLIMVCNPSI-QFMIYETLSKRLQSKRSGKRFPKKNITAMEVFL 400 V R GI + GL +L S+ +F IYET+ R+ G + E L Sbjct: 51 VVRTDGILALYSGLSASLCRQMTYSLTRFAIYETVRDRVAKGSQGP------LPFHEKVL 104 Query: 399 LGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFYKG 223 LG+++ L V P +V R+Q ++ + Y LD + ++ R EGL + G Sbjct: 105 LGSVSGLAGGFVGTPADLVNVRMQNDVKLPQGQRRNYAHALDGLYRVAREEGLRRLFSG 163 Score = 37.0 bits (84), Expect = 0.045 Identities = 22/78 (28%), Positives = 39/78 (50%) Frame = -3 Query: 396 GAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFYKGMG 217 G +A GA T+PL ++K LQ +QE+ R TG L+++R +G+ Y G+ Sbjct: 13 GGLASCGAACCTHPLDLLKVHLQTQQEV----KLRMTG---MALRVVRTDGILALYSGLS 65 Query: 216 TKIVQSVFAASVLFMVKE 163 + + + + F + E Sbjct: 66 ASLCRQMTYSLTRFAIYE 83
>CMC2_MACFA (Q8HXW2) Calcium-binding mitochondrial carrier protein Aralar2| (Mitochondrial aspartate glutamate carrier 2) (Solute carrier family 25 member 13) (Citrin) Length = 674 Score = 43.9 bits (102), Expect = 4e-04 Identities = 25/64 (39%), Positives = 39/64 (60%), Gaps = 2/64 (3%) Frame = -3 Query: 405 FLLGAIA-KLGATVVTYPLLVVKSRLQAKQEIGRNAAS-RYTGTLDAILKMIRYEGLHGF 232 F LG++A +GAT V YP+ +VK+R+Q ++ G Y + D K++RYEG G Sbjct: 332 FGLGSVAGAVGATAV-YPIDLVKTRMQNQRSTGSFVGELMYKNSFDCFKKVLRYEGFFGL 390 Query: 231 YKGM 220 Y+G+ Sbjct: 391 YRGL 394 Score = 42.0 bits (97), Expect = 0.001 Identities = 34/142 (23%), Positives = 60/142 (42%), Gaps = 1/142 (0%) Frame = -3 Query: 597 TIQAIREVYRESGISGFWKGLIPTLIMVC-NPSIQFMIYETLSKRLQSKRSGKRFPKKNI 421 + ++V R G G ++GL+P L+ V +I+ + + + + K ++ Sbjct: 374 SFDCFKKVLRYEGFFGLYRGLLPQLLGVAPEKAIKLTVNDFVRDKFMHKDG-------SV 426 Query: 420 TAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGL 241 L G A + T PL +VK RLQ EI TG + L ++R G Sbjct: 427 PLAAEILAGGCAGGSQVIFTNPLEIVKIRLQVAGEI-------TTGPRVSALSVVRDLGF 479 Query: 240 HGFYKGMGTKIVQSVFAASVLF 175 G YKG ++ + +++ F Sbjct: 480 FGIYKGAKACFLRDIPFSAIYF 501 Score = 39.7 bits (91), Expect = 0.007 Identities = 22/62 (35%), Positives = 34/62 (54%) Frame = -3 Query: 408 VFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFY 229 + L GAIA + A + P V+K+RLQ G+ + Y+G +D K++R EG + Sbjct: 523 LLLAGAIAGMPAASLVTPADVIKTRLQVAARAGQ---TTYSGVIDCFKKILREEGPKALW 579 Query: 228 KG 223 KG Sbjct: 580 KG 581
>UCP1_HUMAN (P25874) Mitochondrial brown fat uncoupling protein 1 (UCP 1)| (Thermogenin) Length = 307 Score = 43.9 bits (102), Expect = 4e-04 Identities = 26/90 (28%), Positives = 48/90 (53%) Frame = -3 Query: 414 MEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHG 235 +++F G A L A V+T+PL K RLQ + E ++ RY G L I +++ EG Sbjct: 15 VQLFSAGIAACL-ADVITFPLDTAKVRLQVQGECPTSSVIRYKGVLGTITAVVKTEGRMK 73 Query: 234 FYKGMGTKIVQSVFAASVLFMVKEELVKFV 145 Y G+ + + + +AS+ + + + +F+ Sbjct: 74 LYSGLPAGLQRQISSASLRIGLYDTVQEFL 103 Score = 42.0 bits (97), Expect = 0.001 Identities = 43/160 (26%), Positives = 71/160 (44%), Gaps = 6/160 (3%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGLIPTLI-MVCNPSIQFMIYETLSKRLQSKRSGKRFPKKN 424 G + I V + G + GL L + + S++ +Y+T+ + L + K+ Sbjct: 57 GVLGTITAVVKTEGRMKLYSGLPAGLQRQISSASLRIGLYDTVQEFLTAG-------KET 109 Query: 423 ITAMEVFLLGAIAKLGATV-VTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYE 247 ++ +L + G V + P VVK RLQA+ + RYTGT +A + E Sbjct: 110 APSLGSKILAGLTTGGVAVFIGQPTEVVKVRLQAQSHL-HGIKPRYTGTYNAYRIIATTE 168 Query: 246 GLHGFYKGMGTKIVQSVFAASVLF----MVKEELVKFVIL 139 GL G +KG +++SV ++KE VK IL Sbjct: 169 GLTGLWKGTTPNLMRSVIINCTELVTYDLMKEAFVKNNIL 208
>MTCH2_PONPY (Q5R5M0) Mitochondrial carrier homolog 2| Length = 303 Score = 43.5 bits (101), Expect = 5e-04 Identities = 33/133 (24%), Positives = 62/133 (46%), Gaps = 9/133 (6%) Frame = -3 Query: 561 GISGFWKGLIPTLIMVCNPSIQFMIYETLSKRLQSKRSGKRFPKKNIT---------AME 409 G G + GL P L C+ + +++ + + Q G+ N+ ++ Sbjct: 66 GRRGLFTGLTPRL---CSGVLGTVVHGKVLQHYQESDKGEELGPGNVQKEVSSSFDHVIK 122 Query: 408 VFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFY 229 IA+ AT++T+P V+ R Q IGR S+Y G D+I+ + R EG+ GF+ Sbjct: 123 ETTREMIARSAATLITHPFHVITLRSMV-QFIGRE--SKYCGLCDSIITIYREEGILGFF 179 Query: 228 KGMGTKIVQSVFA 190 G+ +++ + + Sbjct: 180 AGLVPRLLGDILS 192 Score = 34.7 bits (78), Expect = 0.23 Identities = 27/103 (26%), Positives = 44/103 (42%), Gaps = 6/103 (5%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGLIPTL------IMVCNPSIQFMIYETLSKRLQSKRSGKR 439 G +I +YRE GI GF+ GL+P L + +CN + L + + K Sbjct: 161 GLCDSIITIYREEGILGFFAGLVPRLLGDILSLWLCNSLAYLVNTYALDSGVSTMNEMKS 220 Query: 438 FPKKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIG 310 + + A+ A+++TYP ++V S L A G Sbjct: 221 YSQ------------AVTGFFASMLTYPFVLV-SNLMAVNNCG 250
>MTCH2_HUMAN (Q9Y6C9) Mitochondrial carrier homolog 2 (Met-induced mitochondrial| protein) Length = 303 Score = 43.5 bits (101), Expect = 5e-04 Identities = 33/133 (24%), Positives = 62/133 (46%), Gaps = 9/133 (6%) Frame = -3 Query: 561 GISGFWKGLIPTLIMVCNPSIQFMIYETLSKRLQSKRSGKRFPKKNIT---------AME 409 G G + GL P L C+ + +++ + + Q G+ N+ ++ Sbjct: 66 GRRGLFTGLTPRL---CSGVLGTVVHGKVLQHYQESDKGEELGPGNVQKEVSSSFDHVIK 122 Query: 408 VFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFY 229 IA+ AT++T+P V+ R Q IGR S+Y G D+I+ + R EG+ GF+ Sbjct: 123 ETTREMIARSAATLITHPFHVITLRSMV-QFIGRE--SKYCGLCDSIITIYREEGILGFF 179 Query: 228 KGMGTKIVQSVFA 190 G+ +++ + + Sbjct: 180 AGLVPRLLGDILS 192 Score = 34.7 bits (78), Expect = 0.23 Identities = 27/103 (26%), Positives = 44/103 (42%), Gaps = 6/103 (5%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGLIPTL------IMVCNPSIQFMIYETLSKRLQSKRSGKR 439 G +I +YRE GI GF+ GL+P L + +CN + L + + K Sbjct: 161 GLCDSIITIYREEGILGFFAGLVPRLLGDILSLWLCNSLAYLVNTYALDSGVSTMNEMKS 220 Query: 438 FPKKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIG 310 + + A+ A+++TYP ++V S L A G Sbjct: 221 YSQ------------AVTGFFASMLTYPFVLV-SNLMAVNNCG 250
>UCP2_PIG (O97562) Mitochondrial uncoupling protein 2 (UCP 2)| Length = 309 Score = 43.1 bits (100), Expect = 6e-04 Identities = 43/163 (26%), Positives = 72/163 (44%), Gaps = 5/163 (3%) Frame = -3 Query: 597 TIQAIREVYRESGISGFWKGLIPTL----IMVCNPSIQF-MIYETLSKRLQSKRSGKRFP 433 T+ A + + RE G+ G WKG P + I+ C + + +I +TL L++ P Sbjct: 159 TVDAYKTIAREEGLRGLWKGTSPNVARNAIVNCAELVTYDLIKDTL---LKADLMTDDLP 215 Query: 432 KKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIR 253 +A A TV+ P+ VVK+R +A +Y+ L M++ Sbjct: 216 CHFTSAFG-------AGFCTTVIASPVDVVKTRYM------NSAPGQYSSAGHCALTMLQ 262 Query: 252 YEGLHGFYKGMGTKIVQSVFAASVLFMVKEELVKFVILLVARS 124 EG FYKG ++ V+F+ E+L + L+ AR+ Sbjct: 263 KEGPRAFYKGFTPSFLRLGSWNVVMFVTYEQLKR--ALMAARA 303 Score = 43.1 bits (100), Expect = 6e-04 Identities = 29/84 (34%), Positives = 42/84 (50%), Gaps = 4/84 (4%) Frame = -3 Query: 420 TAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQE----IGRNAASRYTGTLDAILKMIR 253 TA FL A A ++T+PL K RLQ + E + A+++Y G L IL M+R Sbjct: 12 TATVKFLGAGTAACIADLITFPLDTAKVRLQIQGERRGPVQAAASAQYRGVLGTILTMVR 71 Query: 252 YEGLHGFYKGMGTKIVQSVFAASV 181 EG Y G+ + + + ASV Sbjct: 72 NEGPRSLYNGLVAGLQRQMSFASV 95 Score = 42.4 bits (98), Expect = 0.001 Identities = 40/155 (25%), Positives = 67/155 (43%), Gaps = 1/155 (0%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGLIPTLIMVCN-PSIQFMIYETLSKRLQSKRSGKRFPKKN 424 G + I + R G + GL+ L + S++ +Y+++ K +K S ++ Sbjct: 61 GVLGTILTMVRNEGPRSLYNGLVAGLQRQMSFASVRIGLYDSV-KHFYTKGS------EH 113 Query: 423 ITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEG 244 L G+ A V P VVK R QA+ G RY T+DA + R EG Sbjct: 114 AGIGSRLLAGSTTGALAVAVAQPTDVVKVRFQAQARAG--GGRRYRSTVDAYKTIAREEG 171 Query: 243 LHGFYKGMGTKIVQSVFAASVLFMVKEELVKFVIL 139 L G +KG + ++ + +V +L+K +L Sbjct: 172 LRGLWKGTSPNVARNAI-VNCAELVTYDLIKDTLL 205
>UCP2_CANFA (Q9N2J1) Mitochondrial uncoupling protein 2 (UCP 2)| Length = 309 Score = 43.1 bits (100), Expect = 6e-04 Identities = 30/95 (31%), Positives = 47/95 (49%), Gaps = 4/95 (4%) Frame = -3 Query: 420 TAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQE----IGRNAASRYTGTLDAILKMIR 253 TA FL A A ++T+PL K RLQ + E + A+++Y G L IL M+R Sbjct: 12 TATVKFLGAGTAACIADLITFPLDTAKVRLQIQGERQGPVRAAASAQYRGVLCTILTMVR 71 Query: 252 YEGLHGFYKGMGTKIVQSVFAASVLFMVKEELVKF 148 EG Y G+ + + + ASV + + + +F Sbjct: 72 TEGPRSLYSGLVAGLQRQMSFASVRIGLYDSVKQF 106 Score = 40.8 bits (94), Expect = 0.003 Identities = 39/155 (25%), Positives = 68/155 (43%), Gaps = 1/155 (0%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGLIPTLIMVCN-PSIQFMIYETLSKRLQSKRSGKRFPKKN 424 G + I + R G + GL+ L + S++ +Y+++ K+ +K S ++ Sbjct: 61 GVLCTILTMVRTEGPRSLYSGLVAGLQRQMSFASVRIGLYDSV-KQFYTKGS------EH 113 Query: 423 ITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEG 244 L G+ A V P VVK R QA+ G + RY T+DA + R EG Sbjct: 114 AGIGSRLLAGSTTGALAVAVAQPTDVVKVRFQAQARAG--SGRRYQSTVDAYKTIAREEG 171 Query: 243 LHGFYKGMGTKIVQSVFAASVLFMVKEELVKFVIL 139 G +KG + ++ + +V +L+K +L Sbjct: 172 FRGLWKGTSPNVARNAI-VNCAELVTYDLIKDALL 205
>UCP1_CANFA (Q9GMZ1) Mitochondrial brown fat uncoupling protein 1 (UCP 1)| (Thermogenin) Length = 309 Score = 43.1 bits (100), Expect = 6e-04 Identities = 37/152 (24%), Positives = 67/152 (44%), Gaps = 4/152 (2%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGLIPTLIM-VCNPSIQFMIYETLSKRLQSKRSGKRFPKKN 424 GT A R + G++G WKG P L+ V + + Y+ + + L K + Sbjct: 158 GTYNAYRIIATTEGLTGLWKGTTPNLMRNVIINCTELVTYDLMKEALV---------KNH 208 Query: 423 ITAMEV---FLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIR 253 + A ++ FL +A TV++ P+ VVK+R + +YT + + M+ Sbjct: 209 LLADDLPCHFLSALVAGFCTTVLSSPVDVVKTRFV------NSVPEQYTSVPNCAMTMLT 262 Query: 252 YEGLHGFYKGMGTKIVQSVFAASVLFMVKEEL 157 EG F+KG ++ ++F+ E+L Sbjct: 263 KEGPLAFFKGFVPSFLRLGSWNVIMFVCFEQL 294 Score = 40.8 bits (94), Expect = 0.003 Identities = 40/155 (25%), Positives = 67/155 (43%), Gaps = 5/155 (3%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGLIPTLI-MVCNPSIQFMIYETLSKRLQSKRSGKRFPKKN 424 G + + + R G+ + GL L V S++ +Y+++ + L + Sbjct: 59 GVLGTVATLARTEGLQKLYSGLPAGLQRQVGFASLRIGLYDSVREWLSPGQGAAASLGSR 118 Query: 423 ITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEG 244 I+A G + A + P VVK RLQA+ + RYTGT +A + EG Sbjct: 119 ISA------GVMTGGAAVFIGQPTEVVKVRLQAQSHL-HGRKPRYTGTYNAYRIIATTEG 171 Query: 243 LHGFYKGMGTKIVQSVFAASVLF----MVKEELVK 151 L G +KG ++++V ++KE LVK Sbjct: 172 LTGLWKGTTPNLMRNVIINCTELVTYDLMKEALVK 206 Score = 36.6 bits (83), Expect = 0.059 Identities = 24/68 (35%), Positives = 35/68 (51%), Gaps = 3/68 (4%) Frame = -3 Query: 375 ATVVTYPLLVVKSRLQAKQEIGRNA---ASRYTGTLDAILKMIRYEGLHGFYKGMGTKIV 205 A ++T+PL K RLQ + E G+ A RY G L + + R EGL Y G+ + Sbjct: 27 ADMITFPLDTAKVRLQIQGE-GQGQPPRAPRYRGVLGTVATLARTEGLQKLYSGLPAGLQ 85 Query: 204 QSVFAASV 181 + V AS+ Sbjct: 86 RQVGFASL 93
>UCP1_BOVIN (P10861) Mitochondrial brown fat uncoupling protein 1 (UCP 1)| (Thermogenin) (Fragment) Length = 288 Score = 43.1 bits (100), Expect = 6e-04 Identities = 44/154 (28%), Positives = 67/154 (43%), Gaps = 18/154 (11%) Frame = -3 Query: 546 WKGLIPTLIMVCNPSIQFMIYETLSKRLQSKRS--GKRFPKKNITAMEVFLLGAIAKLGA 373 +KG++ T+I + +Y L LQ + S R + T E F G A LG+ Sbjct: 39 YKGVLGTIITLAKTEGPVKLYSGLPAGLQRQISLASLRIGLYD-TVQEFFTTGKEASLGS 97 Query: 372 TV------------VTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFY 229 + + P VVK RLQA+ + RYTGT +A + EGL G + Sbjct: 98 KISAGLMTGGVAVFIGQPTEVVKVRLQAQSHL-HGPKPRYTGTYNAYRIIATTEGLTGLW 156 Query: 228 KG----MGTKIVQSVFAASVLFMVKEELVKFVIL 139 KG + T ++ + ++KE LVK +L Sbjct: 157 KGTSPNLTTNVIINCTELVTYDLMKEALVKNKLL 190 Score = 40.4 bits (93), Expect = 0.004 Identities = 23/81 (28%), Positives = 42/81 (51%) Frame = -3 Query: 390 IAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFYKGMGTK 211 +A A ++T+PL K RLQ + E ++A RY G L I+ + + EG Y G+ Sbjct: 6 VAACVADIITFPLDTAKVRLQIQGECLISSAIRYKGVLGTIITLAKTEGPVKLYSGLPAG 65 Query: 210 IVQSVFAASVLFMVKEELVKF 148 + + + AS+ + + + +F Sbjct: 66 LQRQISLASLRIGLYDTVQEF 86
>UCP1_PHOSU (Q9ER18) Mitochondrial brown fat uncoupling protein 1 (UCP 1)| (Thermogenin) Length = 307 Score = 42.7 bits (99), Expect = 8e-04 Identities = 26/78 (33%), Positives = 41/78 (52%) Frame = -3 Query: 414 MEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHG 235 +++F G A L A ++T+PL K RLQ + E ++ RY G L I + + EGL Sbjct: 15 VKIFSAGVAACL-ADIITFPLDTAKVRLQIQGEGQTSSTIRYKGVLGTITTLAKTEGLPK 73 Query: 234 FYKGMGTKIVQSVFAASV 181 Y G+ I + + AS+ Sbjct: 74 LYSGLPAGIQRQISFASL 91 Score = 37.0 bits (84), Expect = 0.045 Identities = 36/138 (26%), Positives = 62/138 (44%), Gaps = 3/138 (2%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGLIPTLIM--VCNPSIQFMIYETLSKRLQSKRSGKRFPKK 427 G + I + + G+ + GL P I + S++ +Y+T+ + S GK P Sbjct: 57 GVLGTITTLAKTEGLPKLYSGL-PAGIQRQISFASLRIGLYDTVQEYFSS---GKETPPT 112 Query: 426 NITAMEVFLL-GAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRY 250 + + L+ G +A + P VVK RLQA+ + RYTGT +A + Sbjct: 113 LVNRISAGLMTGGVA----VFIGQPTEVVKVRLQAQSHL-HGIKPRYTGTYNAYRIIATT 167 Query: 249 EGLHGFYKGMGTKIVQSV 196 E L +KG ++++V Sbjct: 168 ESLSTLWKGTTPNLLRNV 185
>GDC_HUMAN (P16260) Grave disease carrier protein (GDC) (Grave disease| autoantigen) (GDA) (Mitochondrial solute carrier protein homolog) (Solute carrier family 25 member 16) Length = 332 Score = 42.7 bits (99), Expect = 8e-04 Identities = 39/163 (23%), Positives = 69/163 (42%), Gaps = 12/163 (7%) Frame = -3 Query: 600 GTIQAIREVY-RESGISGFWKGLIPTLI-MVCNPSIQFMIYETLS----KRLQSKRSGKR 439 G I A + +Y +E G GF++GL+PT++ M + F + TL + Sbjct: 170 GIIHAFKTIYAKEGGFFGFYRGLMPTILGMAPYAGVSFFTFGTLKSVGLSHAPTLLGSPS 229 Query: 438 FPKKNITAMEV---FLLGAIAKLGATVVTYPLLVVKSRLQ---AKQEIGRNAASRYTGTL 277 N+ ++ L G +A+ A ++YP V + R+Q E + R T Sbjct: 230 SDNPNVLVLKTHVNLLCGGVARAIAQTISYPFDVTRRRMQLGTVLPEFEKCLTMRDTMKY 289 Query: 276 DAILKMIRYEGLHGFYKGMGTKIVQSVFAASVLFMVKEELVKF 148 D IR G Y+G+ ++ + + +V F E + +F Sbjct: 290 DYGHHGIR----KGLYRGLSLNYIRCIPSQAVAFTTYELMKQF 328
>UCP1_RAT (P04633) Mitochondrial brown fat uncoupling protein 1 (UCP 1)| (Thermogenin) Length = 306 Score = 42.4 bits (98), Expect = 0.001 Identities = 26/78 (33%), Positives = 41/78 (52%) Frame = -3 Query: 414 MEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHG 235 +++F G A L A ++T+PL K RLQ + E ++ RY G L I + + EGL Sbjct: 14 VKIFSAGVSACL-ADIITFPLDTAKVRLQIQGEGQASSTIRYKGVLGTITTLAKTEGLPK 72 Query: 234 FYKGMGTKIVQSVFAASV 181 Y G+ I + + AS+ Sbjct: 73 LYSGLPAGIQRQISFASL 90 Score = 35.0 bits (79), Expect = 0.17 Identities = 34/137 (24%), Positives = 59/137 (43%), Gaps = 2/137 (1%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGLIPTLIM--VCNPSIQFMIYETLSKRLQSKRSGKRFPKK 427 G + I + + G+ + GL P I + S++ +Y+T+ + S R Sbjct: 56 GVLGTITTLAKTEGLPKLYSGL-PAGIQRQISFASLRIGLYDTVQEYFSSGRETPASLGS 114 Query: 426 NITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYE 247 I+A G + A + P VVK R+QA+ + RYTGT +A + E Sbjct: 115 KISA------GLMTGGVAVFIGQPTEVVKVRMQAQSHL-HGIKPRYTGTYNAYRVIATTE 167 Query: 246 GLHGFYKGMGTKIVQSV 196 L +KG ++++V Sbjct: 168 SLSTLWKGTTPNLMRNV 184
>UCP1_MOUSE (P12242) Mitochondrial brown fat uncoupling protein 1 (UCP 1)| (Thermogenin) Length = 306 Score = 42.4 bits (98), Expect = 0.001 Identities = 26/78 (33%), Positives = 41/78 (52%) Frame = -3 Query: 414 MEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHG 235 +++F G A L A ++T+PL K RLQ + E ++ RY G L I + + EGL Sbjct: 14 VKIFSAGVSACL-ADIITFPLDTAKVRLQIQGEGQASSTIRYKGVLGTITTLAKTEGLPK 72 Query: 234 FYKGMGTKIVQSVFAASV 181 Y G+ I + + AS+ Sbjct: 73 LYSGLPAGIQRQISFASL 90 Score = 33.5 bits (75), Expect = 0.50 Identities = 33/137 (24%), Positives = 59/137 (43%), Gaps = 2/137 (1%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGLIPTLIM--VCNPSIQFMIYETLSKRLQSKRSGKRFPKK 427 G + I + + G+ + GL P I + S++ +Y+++ + S R Sbjct: 56 GVLGTITTLAKTEGLPKLYSGL-PAGIQRQISFASLRIGLYDSVQEYFSSGRETPASLGN 114 Query: 426 NITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYE 247 I+A G + A + P VVK R+QA+ + RYTGT +A + E Sbjct: 115 KISA------GLMTGGVAVFIGQPTEVVKVRMQAQSHL-HGIKPRYTGTYNAYRVIATTE 167 Query: 246 GLHGFYKGMGTKIVQSV 196 L +KG ++++V Sbjct: 168 SLSTLWKGTTPNLMRNV 184
>UCP1_MESAU (P04575) Mitochondrial brown fat uncoupling protein 1 (UCP 1)| (Thermogenin) Length = 306 Score = 42.0 bits (97), Expect = 0.001 Identities = 26/78 (33%), Positives = 41/78 (52%) Frame = -3 Query: 414 MEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHG 235 +++F G A L A ++T+PL K RLQ + E ++ RY G L I + + EGL Sbjct: 14 VKIFSAGVAACL-ADIITFPLDTAKVRLQIQGEGQISSTIRYKGVLGTITTLAKTEGLPK 72 Query: 234 FYKGMGTKIVQSVFAASV 181 Y G+ I + + AS+ Sbjct: 73 LYSGLPAGIQRQISFASL 90 Score = 33.1 bits (74), Expect = 0.66 Identities = 35/137 (25%), Positives = 58/137 (42%), Gaps = 2/137 (1%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGLIPTLIM--VCNPSIQFMIYETLSKRLQSKRSGKRFPKK 427 G + I + + G+ + GL P I + S++ +Y+T+ + S GK P Sbjct: 56 GVLGTITTLAKTEGLPKLYSGL-PAGIQRQISFASLRIGLYDTVQEYFSS---GKETPP- 110 Query: 426 NITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYE 247 T G + A + P VVK RLQA+ + RYTGT +A + E Sbjct: 111 --TLGNRISAGLMTGGVAVFIGQPTEVVKVRLQAQSHL-HGIKPRYTGTYNAYRIIATTE 167 Query: 246 GLHGFYKGMGTKIVQSV 196 +KG ++++V Sbjct: 168 SFSTLWKGTTPNLLRNV 184
>ADT1_ANOGA (Q27238) ADP,ATP carrier protein 1 (ADP/ATP translocase 1) (Adenine| nucleotide translocator 1) (ANT 1) Length = 301 Score = 42.0 bits (97), Expect = 0.001 Identities = 31/147 (21%), Positives = 61/147 (41%), Gaps = 1/147 (0%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGLIPTLIMVCNPSIQ-FMIYETLSKRLQSKRSGKRFPKKN 424 G + +++ + GI G ++G N S+Q +IY G KN Sbjct: 158 GLLDCLKKTVKSDGIIGLYRGF--------NVSVQGIIIYRAAYFGCFDTAKGMLPDPKN 209 Query: 423 ITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEG 244 + + + + + +++YP V+ R+ + ++ Y TLD +K+ + EG Sbjct: 210 TSIFVSWAIAQVVTTASGIISYPFDTVRRRMMMQSGRAKSEVM-YKNTLDCWVKIGKQEG 268 Query: 243 LHGFYKGMGTKIVQSVFAASVLFMVKE 163 F+KG + +++ A VL E Sbjct: 269 SGAFFKGAFSNVLRGTGGALVLVFYDE 295
>UCP2_BRARE (Q9W720) Mitochondrial uncoupling protein 2 (UCP 2)| Length = 310 Score = 42.0 bits (97), Expect = 0.001 Identities = 40/155 (25%), Positives = 67/155 (43%), Gaps = 1/155 (0%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGLIPTLIMVCN-PSIQFMIYETLSKRLQSKRSGKRFPKKN 424 G I + R G + GL+ L + S++ +Y+++ K+ +K S Sbjct: 62 GVFGTISTMVRVEGPRSLYSGLVAGLQRQMSFASVRIGLYDSV-KQFYTKGSDHAGIGSR 120 Query: 423 ITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEG 244 + A G A V P V+K R QA+ G A+ RY T+DA + + EG Sbjct: 121 LMA------GCTTGAMAVAVAQPTDVLKVRFQAQVSAG--ASKRYHSTMDAYRTIAKEEG 172 Query: 243 LHGFYKGMGTKIVQSVFAASVLFMVKEELVKFVIL 139 G +KG G I ++ + +V +L+K +L Sbjct: 173 FRGLWKGTGPNITRNAI-VNCTELVTYDLIKDALL 206 Score = 36.2 bits (82), Expect = 0.077 Identities = 29/99 (29%), Positives = 43/99 (43%), Gaps = 8/99 (8%) Frame = -3 Query: 420 TAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAAS--------RYTGTLDAIL 265 TA F+ A A + T+PL K RLQ + G N AS +Y G I Sbjct: 12 TATVKFIGAGTAACIADLFTFPLDTAKVRLQIQ---GENKASTNMGRGPVKYRGVFGTIS 68 Query: 264 KMIRYEGLHGFYKGMGTKIVQSVFAASVLFMVKEELVKF 148 M+R EG Y G+ + + + ASV + + + +F Sbjct: 69 TMVRVEGPRSLYSGLVAGLQRQMSFASVRIGLYDSVKQF 107
>ADT3_PIG (Q6QRN9) ADP/ATP translocase 3 (Adenine nucleotide translocator 2)| (ANT 3) (ADP,ATP carrier protein 3) (Solute carrier family 25 member 6) Length = 297 Score = 41.6 bits (96), Expect = 0.002 Identities = 35/141 (24%), Positives = 61/141 (43%), Gaps = 2/141 (1%) Frame = -3 Query: 579 EVYRESGISGFWKGLIPTLIMVCNPSIQ-FMIYETLSKRLQSKRSGKRFPKKNITAMEVF 403 ++ + GI G ++G N S+Q +IY + G +N + + Sbjct: 162 KITKSDGIRGLYQGF--------NVSVQGIIIYRAAYFGVYGTAKGMLPDPRNTHIVVSW 213 Query: 402 LLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAAS-RYTGTLDAILKMIRYEGLHGFYK 226 ++ A V +YP V+ R+ + GR A Y GTLD K+ + EG F+K Sbjct: 214 MIAQTVTAVAGVFSYPFDTVRRRMMMQS--GRKGADIMYKGTLDCWRKIFKDEGGKAFFK 271 Query: 225 GMGTKIVQSVFAASVLFMVKE 163 G + +++ + A VL + E Sbjct: 272 GAWSNVLRGMGGAFVLVLYDE 292
>ADT_DROME (Q26365) ADP,ATP carrier protein (ADP/ATP translocase) (Adenine| nucleotide translocator) (ANT) (Stress sensitive B protein) Length = 312 Score = 41.6 bits (96), Expect = 0.002 Identities = 31/136 (22%), Positives = 56/136 (41%), Gaps = 5/136 (3%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGLIPTLIMVCNPSIQFMIYETLSKRLQSKRSGKRFPKKNI 421 G + + +E G S FW+G + +I ++ K++ K Sbjct: 68 GMVDCFIRIPKEQGFSSFWRGNLANVIRYFPTQALNFAFKDKYKQVFLGGVDKN------ 121 Query: 420 TAMEVFLLGAIAKLGATVVT-----YPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMI 256 T + G +A GA T YPL ++RL A + G+ +TG + + K+ Sbjct: 122 TQFWRYFAGNLASGGAAGATSLCFVYPLDFARTRLAA--DTGKGGQREFTGLGNCLTKIF 179 Query: 255 RYEGLHGFYKGMGTKI 208 + +G+ G Y+G G + Sbjct: 180 KSDGIVGLYRGFGVSV 195
>MFN2B_XENLA (Q68F18) Mitoferrin-2B (Mitochondrial iron transporter 2-B) (Solute| carrier family 25 member 28-B) Length = 186 Score = 41.6 bits (96), Expect = 0.002 Identities = 29/92 (31%), Positives = 49/92 (53%) Frame = -3 Query: 426 NITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYE 247 N+TA L GA+A + + YP+ VK+R+Q+ Q + A+RY +DA+ K++R E Sbjct: 76 NVTAH--MLAGAVAGVMEHCLMYPVDCVKTRMQSLQP---DPAARYRNVMDALSKIVRTE 130 Query: 246 GLHGFYKGMGTKIVQSVFAASVLFMVKEELVK 151 G +G+ + A ++ F E+L K Sbjct: 131 GFWRPLRGLNVTATGAGPAHALYFACYEKLKK 162
>MFN2A_XENLA (Q6GLJ0) Mitoferrin-2A (Mitochondrial iron transporter 2-A) (Solute| carrier family 25 member 28-A) Length = 186 Score = 41.6 bits (96), Expect = 0.002 Identities = 36/139 (25%), Positives = 64/139 (46%), Gaps = 7/139 (5%) Frame = -3 Query: 546 WKGLIPTLIMVCNPSIQFMIYETLSKRLQSKRSGKRFPK-------KNITAMEVFLLGAI 388 W P+++ S + +E+ S R+ S P+ N+T L GA+ Sbjct: 29 WSAAGPSVLESEGGSGGPLAFESTSSRILELASKDNEPEYEALPDGSNVTTH--MLAGAV 86 Query: 387 AKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFYKGMGTKI 208 A + + YP+ VK+R+Q+ Q + A+RY +DA+ K++R EG +G+ Sbjct: 87 AGVMEHCLMYPVDCVKTRMQSLQP---DPAARYRNVMDALSKIVRTEGFWRPLRGLNVTA 143 Query: 207 VQSVFAASVLFMVKEELVK 151 + A ++ F E+L K Sbjct: 144 TGAGPAHALYFACYEKLKK 162
>MTCH2_MOUSE (Q791V5) Mitochondrial carrier homolog 2| Length = 303 Score = 41.2 bits (95), Expect = 0.002 Identities = 23/67 (34%), Positives = 40/67 (59%) Frame = -3 Query: 390 IAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFYKGMGTK 211 IA+ AT++T+P V+ R Q IGR S+Y G D+I+ + R EG+ GF+ G+ + Sbjct: 129 IARSAATLITHPFHVITLRSMV-QFIGRE--SKYCGLCDSIVTIYREEGIVGFFAGLIPR 185 Query: 210 IVQSVFA 190 ++ + + Sbjct: 186 LLGDIIS 192 Score = 35.0 bits (79), Expect = 0.17 Identities = 28/103 (27%), Positives = 44/103 (42%), Gaps = 6/103 (5%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGLIPTL------IMVCNPSIQFMIYETLSKRLQSKRSGKR 439 G +I +YRE GI GF+ GLIP L + +CN + L + + K Sbjct: 161 GLCDSIVTIYREEGIVGFFAGLIPRLLGDIISLWLCNSLAYLINTYALDSGVSTMNEMKS 220 Query: 438 FPKKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIG 310 + + A+ A+++TYP ++V S L A G Sbjct: 221 YSQ------------AVTGFFASMLTYPFVLV-SNLMAVNNCG 250
>YM39_YEAST (Q03829) Putative mitochondrial carrier YMR166C| Length = 368 Score = 40.8 bits (94), Expect = 0.003 Identities = 41/157 (26%), Positives = 73/157 (46%), Gaps = 17/157 (10%) Frame = -3 Query: 588 AIREVYRESGISGFWKGLIPTLIM-VCNPSIQFMIYETLSKRLQSKRSGKRFPKKNITAM 412 AI+ V +E G + G TL + ++QF YE ++L K K ++ Sbjct: 199 AIKTVIKEEGFRSLFFGYKATLARDLPFSALQFAFYEKF-RQLAFKIEQKDGRDGELSIP 257 Query: 411 EVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEI----------------GRNAASRYTGT 280 L GA A A ++T P+ VVK+R+Q +Q GR AA + + Sbjct: 258 NEILTGACAGGLAGIITTPMDVVKTRVQTQQPPSQSNKSYSVTHPHVTNGRPAALSNSIS 317 Query: 279 LDAILKMIRYEGLHGFYKGMGTKIVQSVFAASVLFMV 169 L ++ + + EG+ GF+ G+G + V + +S++ ++ Sbjct: 318 L-SLRTVYQSEGVLGFFSGVGPRFVWTSVQSSIMLLL 353
>MFRN2_HUMAN (Q96A46) Mitoferrin-2 (Mitochondrial iron transporter 2) (Solute| carrier family 25 member 28) (Mitochondrial RNA splicing protein 3/4 homolog) (MRS3/4) (hMRS3/4) Length = 364 Score = 40.8 bits (94), Expect = 0.003 Identities = 27/82 (32%), Positives = 45/82 (54%) Frame = -3 Query: 396 GAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFYKGMG 217 GA+A + V YP+ VK+R+Q+ Q + A+RY L+A+ ++IR EGL +G+ Sbjct: 79 GAVAGILEHCVMYPIDCVKTRMQSLQP---DPAARYRNVLEALWRIIRTEGLWRPMRGLN 135 Query: 216 TKIVQSVFAASVLFMVKEELVK 151 + A ++ F E+L K Sbjct: 136 VTATGAGPAHALYFACYEKLKK 157
>MPCP_RAT (P16036) Phosphate carrier protein, mitochondrial precursor (PTP)| (Solute carrier family 25 member 3) Length = 356 Score = 40.8 bits (94), Expect = 0.003 Identities = 43/149 (28%), Positives = 66/149 (44%), Gaps = 6/149 (4%) Frame = -3 Query: 570 RESGISGFWKGLIPTLIMVCNPSI-QFMIYETLSKRLQSKRSGKRFPKKNITAMEVFLLG 394 +E G+ G KG PTLI + +F YE K L S G+ T++ + Sbjct: 106 KEDGVRGLAKGWAPTLIGYSMQGLCKFGFYEVF-KALYSNILGEENTYLWRTSLYL-AAS 163 Query: 393 AIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTL-DAILKMIRYEGLHGFYKGMG 217 A A+ A + P+ K R+Q + Y TL +A+ KM + EGL+ FYKG+ Sbjct: 164 ASAEFFADIALAPMEAAKVRIQTQPG--------YANTLREAVPKMYKEEGLNAFYKGVA 215 Query: 216 ----TKIVQSVFAASVLFMVKEELVKFVI 142 +I ++ + E L KFV+ Sbjct: 216 PVWMRQIPYTMMKFACFERTVEALYKFVV 244 Score = 34.7 bits (78), Expect = 0.23 Identities = 32/134 (23%), Positives = 63/134 (47%), Gaps = 5/134 (3%) Frame = -3 Query: 591 QAIREVYRESGISGFWKGLIPT-LIMVCNPSIQFMIYETLSKRLQSKRSGKRFPKKNITA 415 +A+ ++Y+E G++ F+KG+ P + + ++F +E + L K P+ T Sbjct: 196 EAVPKMYKEEGLNAFYKGVAPVWMRQIPYTMMKFACFERTVEALYKFVVPK--PRSECTK 253 Query: 414 ME----VFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYE 247 E F+ G IA + +V++P V S L +E G A+ ++++ Sbjct: 254 AEQLVVTFVAGYIAGVFCAIVSHPADSVVSVL--NKEKGSTAS-----------QVLQRL 300 Query: 246 GLHGFYKGMGTKIV 205 G G +KG+ +I+ Sbjct: 301 GFRGVWKGLFARII 314
>GDC_RAT (P16261) Grave disease carrier protein (GDC) (Mitochondrial solute| carrier protein homolog) (Solute carrier family 25 member 16) (Fragment) Length = 322 Score = 40.4 bits (93), Expect = 0.004 Identities = 36/152 (23%), Positives = 68/152 (44%), Gaps = 10/152 (6%) Frame = -3 Query: 600 GTIQAIREVY-RESGISGFWKGLIPTLI-MVCNPSIQFMIYETLSKRLQS------KRSG 445 G I A + +Y +E G GF++GL+PT++ M S+ F + TL S R Sbjct: 173 GIIHAFKTIYAKEGGFLGFYRGLMPTILGMAPYASVSFFTFGTLKSVGLSYAPTLLGRPS 232 Query: 444 KRFPKKNITAMEVFLL-GAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAI 268 P + + LL G +A+ A ++YP V + R+Q + + + + Sbjct: 233 SDNPNVLVLKTHINLLCGGVARAIAQTISYPFDVTRRRMQLGAVLPE--FEKCLTMRETM 290 Query: 267 LKMIRYEGL-HGFYKGMGTKIVQSVFAASVLF 175 + + G+ G Y+G+ ++ + + +V F Sbjct: 291 KYVYGHHGIRRGLYRGLSLNYIRCIPSQAVAF 322
>MPCP_MOUSE (Q8VEM8) Phosphate carrier protein, mitochondrial precursor (PTP)| (Solute carrier family 25 member 3) Length = 357 Score = 40.4 bits (93), Expect = 0.004 Identities = 43/149 (28%), Positives = 66/149 (44%), Gaps = 6/149 (4%) Frame = -3 Query: 570 RESGISGFWKGLIPTLIMVCNPSI-QFMIYETLSKRLQSKRSGKRFPKKNITAMEVFLLG 394 +E G+ G KG PTLI + +F YE K L S G+ T++ + Sbjct: 107 KEDGVRGLAKGWAPTLIGYSMQGLCKFGFYEVF-KALYSNILGEENTYLWRTSLYL-ASS 164 Query: 393 AIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTL-DAILKMIRYEGLHGFYKGMG 217 A A+ A + P+ K R+Q + Y TL +A+ KM + EGL+ FYKG+ Sbjct: 165 ASAEFFADIALAPMEAAKVRIQTQPG--------YANTLREAVPKMYKEEGLNAFYKGVA 216 Query: 216 ----TKIVQSVFAASVLFMVKEELVKFVI 142 +I ++ + E L KFV+ Sbjct: 217 PLWMRQIPYTMMKFACFERTVEALYKFVV 245 Score = 34.3 bits (77), Expect = 0.29 Identities = 32/134 (23%), Positives = 63/134 (47%), Gaps = 5/134 (3%) Frame = -3 Query: 591 QAIREVYRESGISGFWKGLIPT-LIMVCNPSIQFMIYETLSKRLQSKRSGKRFPKKNITA 415 +A+ ++Y+E G++ F+KG+ P + + ++F +E + L K P+ T Sbjct: 197 EAVPKMYKEEGLNAFYKGVAPLWMRQIPYTMMKFACFERTVEALYKFVVPK--PRSECTK 254 Query: 414 ME----VFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYE 247 E F+ G IA + +V++P V S L +E G A+ ++++ Sbjct: 255 AEQLVVTFVAGYIAGVFCAIVSHPADSVVSVL--NKEKGSTAS-----------QVLQRL 301 Query: 246 GLHGFYKGMGTKIV 205 G G +KG+ +I+ Sbjct: 302 GFRGVWKGLFARII 315
>MFRN1_HUMAN (Q9NYZ2) Mitoferrin-1 (Mitochondrial iron transporter 1) (Solute| carrier family 25 member 37) (Mitochondria solute carrier protein) Length = 347 Score = 40.4 bits (93), Expect = 0.004 Identities = 40/148 (27%), Positives = 66/148 (44%), Gaps = 4/148 (2%) Frame = -3 Query: 588 AIREVYRESGISGFWKGL--IPTLIMVCNPS--IQFMIYETLSKRLQSKRSGKRFPKKNI 421 A++++ R G FW+ L + +IM P+ + F YE + + L F + Sbjct: 90 ALKKIMRTEG---FWRPLRGVNVMIMGAGPAHAMYFACYENMKRTLNDV-----FHHQGN 141 Query: 420 TAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGL 241 + + + G++A L V P VVK RLQ R+A S I + R EGL Sbjct: 142 SHLANGIAGSMATLLHDAVMNPAEVVKQRLQMYNSQHRSAIS-------CIRTVWRTEGL 194 Query: 240 HGFYKGMGTKIVQSVFAASVLFMVKEEL 157 FY+ T++ ++ S+ F+ E L Sbjct: 195 GAFYRSYTTQLTMNIPFQSIHFITYEFL 222 Score = 31.6 bits (70), Expect = 1.9 Identities = 22/80 (27%), Positives = 42/80 (52%) Frame = -3 Query: 396 GAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFYKGMG 217 GA+A + V YP+ VK+R+Q+ + + ++YT A+ K++R EG +G+ Sbjct: 52 GAMAGILEHSVMYPVDSVKTRMQS---LSPDPKAQYTSIYGALKKIMRTEGFWRPLRGVN 108 Query: 216 TKIVQSVFAASVLFMVKEEL 157 I+ + A ++ F E + Sbjct: 109 VMIMGAGPAHAMYFACYENM 128
>MRS4_YEAST (P23500) Mitochondrial RNA-splicing protein MRS4| Length = 304 Score = 40.4 bits (93), Expect = 0.004 Identities = 38/153 (24%), Positives = 60/153 (39%), Gaps = 2/153 (1%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGLIPTLIMVCNPS--IQFMIYETLSKRLQSKRSGKRFPKK 427 G I I ++ G WKG + ++I+ P+ + F YE RL S + Sbjct: 63 GMISQISKISTMEGSMALWKG-VQSVILGAGPAHAVYFGTYEFCKARLISPED-----MQ 116 Query: 426 NITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYE 247 M+ L G IA + A + P VK RLQ + + ++ + E Sbjct: 117 THQPMKTALSGTIATIAADALMNPFDTVKQRLQLDTNLR---------VWNVTKQIYQNE 167 Query: 246 GLHGFYKGMGTKIVQSVFAASVLFMVKEELVKF 148 G FY T + ++ A+ FM+ E KF Sbjct: 168 GFAAFYYSYPTTLAMNIPFAAFNFMIYESASKF 200
>ODC_HUMAN (Q9BQT8) Mitochondrial 2-oxodicarboxylate carrier (Solute carrier| family 25 member 21) Length = 299 Score = 40.0 bits (92), Expect = 0.005 Identities = 35/132 (26%), Positives = 60/132 (45%), Gaps = 7/132 (5%) Frame = -3 Query: 594 IQAIREVYRESGISGFWKGLIPTLIM-VCNPSIQFMIYETLSKRLQSKRSGKRFPKKNIT 418 + + R +++ G+ GF+KG++P ++ +++F +E K L Sbjct: 57 VDSFRMIFQMEGLFGFYKGILPPILAETPKRAVKFFTFEQYKKLL------------GYV 104 Query: 417 AMEVFLLGAIAKLGA----TVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRY 250 ++ L AIA LG+ +V P VVK LQA RN + T+ ++I+ Sbjct: 105 SLSPALTFAIAGLGSGLTEAIVVNPFEVVKVGLQA----NRNTFAEQPSTVGYARQIIKK 160 Query: 249 E--GLHGFYKGM 220 E GL G KG+ Sbjct: 161 EGWGLQGLNKGL 172 Score = 36.6 bits (83), Expect = 0.059 Identities = 26/91 (28%), Positives = 42/91 (46%) Frame = -3 Query: 417 AMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLH 238 A + G A L + +PL VVK+R Q ++ + Y +D+ + + EGL Sbjct: 13 ASRQIVAGGSAGLVEICLMHPLDVVKTRFQIQR--CATDPNSYKSLVDSFRMIFQMEGLF 70 Query: 237 GFYKGMGTKIVQSVFAASVLFMVKEELVKFV 145 GFYKG+ I+ +V F E+ K + Sbjct: 71 GFYKGILPPILAETPKRAVKFFTFEQYKKLL 101 Score = 34.3 bits (77), Expect = 0.29 Identities = 22/81 (27%), Positives = 40/81 (49%) Frame = -3 Query: 405 FLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFYK 226 F +G ++ A+V+ P V KSR+Q Q + +Y + + + EG+ YK Sbjct: 211 FGIGLLSGTIASVINIPFDVAKSRIQGPQPVPGEI--KYRTCFKTMATVYQEEGILALYK 268 Query: 225 GMGTKIVQSVFAASVLFMVKE 163 G+ KI++ +V+ +V E Sbjct: 269 GLLPKIMRLGPGGAVMLLVYE 289
>GDC_BOVIN (Q01888) Grave disease carrier protein (GDC) (Mitochondrial solute| carrier protein homolog) (Solute carrier family 25 member 16) Length = 330 Score = 40.0 bits (92), Expect = 0.005 Identities = 38/161 (23%), Positives = 70/161 (43%), Gaps = 10/161 (6%) Frame = -3 Query: 600 GTIQAIREVY-RESGISGFWKGLIPTLI-MVCNPSIQFMIYETLSKRLQS------KRSG 445 G I A + +Y +E G GF++GL+PT++ M + F + TL S R Sbjct: 168 GIIHAFKTIYAKEGGFLGFYRGLMPTILGMAPYAGVSFFTFGTLKSVGLSYAPTLLGRPS 227 Query: 444 KRFPKKNITAMEVFLL-GAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAI 268 P + + LL G +A A ++YP V + R+Q + + + + Sbjct: 228 SDNPNVLVLKTHINLLCGGVAGAIAQTISYPFDVTRRRMQLGAVLPE--FEKCLTMRETM 285 Query: 267 LKMIRYEGLH-GFYKGMGTKIVQSVFAASVLFMVKEELVKF 148 + + G+ G Y+G+ ++ V + +V F E + +F Sbjct: 286 KYVYGHHGIRKGLYRGLSLNYIRCVPSQAVAFTTYELMKQF 326
>YE08_SCHPO (O13805) Putative mitochondrial carrier C17H9.08| Length = 326 Score = 40.0 bits (92), Expect = 0.005 Identities = 36/120 (30%), Positives = 56/120 (46%), Gaps = 1/120 (0%) Frame = -3 Query: 603 YGTIQAIREVYRESGISGFWKGLIPTLIMVCN-PSIQFMIYETLSKRLQSKRSGKRFPKK 427 +G +AI+ +Y G+ G ++G TL V I+F+ YE Q +R R P+ Sbjct: 60 HGLYKAIKHIYHVYGLHGLYQGHTATLYRVFPYAGIKFVAYE------QVRRVLIRDPEH 113 Query: 426 NITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYE 247 A FL G++A + TYPL +++ RL G+N TL + K I +E Sbjct: 114 ETHARR-FLSGSLAGTCSVFFTYPLELIRVRLAYITNTGKNP------TLTQVTKDIFHE 166 Score = 30.0 bits (66), Expect = 5.6 Identities = 24/87 (27%), Positives = 35/87 (40%) Frame = -3 Query: 402 LLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFYKG 223 + G A A V PL VK Q R A G AI + GLHG Y+G Sbjct: 22 IAGGTAGCVAKSVVAPLDRVKILYQTNHASYRGYAYSRHGLYKAIKHIYHVYGLHGLYQG 81 Query: 222 MGTKIVQSVFAASVLFMVKEELVKFVI 142 + + A + F+ E++ + +I Sbjct: 82 HTATLYRVFPYAGIKFVAYEQVRRVLI 108
>MFRN2_MOUSE (Q8R0Z5) Mitoferrin-2 (Mitochondrial iron transporter 2) (Solute| carrier family 25 member 28) (Mitochondrial RNA splicing protein 3/4 homolog) (MRS3/4) Length = 364 Score = 39.7 bits (91), Expect = 0.007 Identities = 26/82 (31%), Positives = 45/82 (54%) Frame = -3 Query: 396 GAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFYKGMG 217 GA+A + V YP+ VK+R+Q+ Q + A+RY L+A+ +++R EGL +G+ Sbjct: 79 GAVAGILEHCVMYPIDCVKTRMQSLQP---DPAARYRNVLEALWRIMRTEGLWRPMRGLN 135 Query: 216 TKIVQSVFAASVLFMVKEELVK 151 + A ++ F E+L K Sbjct: 136 VTATGAGPAHALYFACYEKLKK 157
>MTCH2_BOVIN (Q9N285) Mitochondrial carrier homolog 2| Length = 303 Score = 39.7 bits (91), Expect = 0.007 Identities = 33/133 (24%), Positives = 66/133 (49%), Gaps = 9/133 (6%) Frame = -3 Query: 561 GISGFWKGLIPTLIMVCNPSIQFMIYETLSKRLQ----SKRSGKRFPKKNITA-----ME 409 G G + GL P L C+ + +++ + + Q ++ SG +K +++ ++ Sbjct: 66 GKRGLFTGLTPRL---CSGILGTVVHGKVLQHYQECDKAEESGSGNVQKEVSSSFDRVIK 122 Query: 408 VFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFY 229 +A+ AT++T+P V+ R Q IGR S+Y G D+I + R EG+ GF+ Sbjct: 123 ETTREMMARSAATLITHPFHVITLRSMV-QFIGRE--SKYCGLCDSIATIYREEGILGFF 179 Query: 228 KGMGTKIVQSVFA 190 G+ +++ + + Sbjct: 180 AGLIPRLLGDIIS 192 Score = 35.8 bits (81), Expect = 0.10 Identities = 28/103 (27%), Positives = 44/103 (42%), Gaps = 6/103 (5%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGLIPTL------IMVCNPSIQFMIYETLSKRLQSKRSGKR 439 G +I +YRE GI GF+ GLIP L + +CN + L + + K Sbjct: 161 GLCDSIATIYREEGILGFFAGLIPRLLGDIISLWLCNSLAYLVNTYALDSGVSTMNEMKS 220 Query: 438 FPKKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIG 310 + + A+ A+++TYP ++V S L A G Sbjct: 221 YSQ------------AVTGFFASMLTYPFVLV-SNLMAVNNCG 250
>GDC_MOUSE (Q8C0K5) Grave disease carrier protein homolog (GDC) (Mitochondrial| solute carrier protein homolog) (Solute carrier family 25 member 16) Length = 332 Score = 39.3 bits (90), Expect = 0.009 Identities = 40/164 (24%), Positives = 68/164 (41%), Gaps = 13/164 (7%) Frame = -3 Query: 600 GTIQAIREVY-RESGISGFWKGLIPTLI-MVCNPSIQFMIYETLSKRLQS------KRSG 445 G I A + +Y +E G GF++GL+PT++ M + F + TL S R Sbjct: 170 GIIHAFKTIYAKEGGFLGFYRGLMPTILGMAPYAGVSFFTFGTLKSVGLSYAPALLGRPS 229 Query: 444 KRFPKKNITAMEVFLL-GAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAI 268 P + + LL G +A A ++YP V + R+Q + + L Sbjct: 230 SDNPNVLVLKTHINLLCGGVAGAIAQTISYPFDVTRRRMQLGAVL-----PEFEKCLTMR 284 Query: 267 LKMIRYEGLH----GFYKGMGTKIVQSVFAASVLFMVKEELVKF 148 M G H G Y+G+ ++ + + +V F E + +F Sbjct: 285 ETMKYVYGQHGIRRGLYRGLSLNYIRCIPSQAVAFTTYELMKQF 328
>ODC_RAT (Q99JD3) Mitochondrial 2-oxodicarboxylate carrier (Solute carrier| family 25 member 21) Length = 298 Score = 38.9 bits (89), Expect = 0.012 Identities = 27/84 (32%), Positives = 39/84 (46%) Frame = -3 Query: 396 GAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFYKGMG 217 G A L + +PL VVK+R Q ++ + Y D+ + R EGL GFYKG+ Sbjct: 19 GGCAGLVEICLMHPLDVVKTRFQVQRSV--TDPQSYKSLRDSFQVIFRTEGLFGFYKGII 76 Query: 216 TKIVQSVFAASVLFMVKEELVKFV 145 I+ +V F E KF+ Sbjct: 77 PPILAETPKRAVKFSTFELYKKFL 100 Score = 37.0 bits (84), Expect = 0.045 Identities = 35/123 (28%), Positives = 53/123 (43%), Gaps = 5/123 (4%) Frame = -3 Query: 576 VYRESGISGFWKGLIPTLIM-VCNPSIQFMIYETLSKRL--QSKRSGKRFPKKNITAMEV 406 ++R G+ GF+KG+IP ++ +++F +E K L S G FP Sbjct: 62 IFRTEGLFGFYKGIIPPILAETPKRAVKFSTFELYKKFLGYMSLSPGLTFP--------- 112 Query: 405 FLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYE--GLHGF 232 + G + L VV P VVK LQ + RN + T ++I+ E G G Sbjct: 113 -IAGLGSGLTEAVVVNPFEVVKVGLQ----VNRNMFTEQPSTFAYARQIIKKEGWGFQGL 167 Query: 231 YKG 223 KG Sbjct: 168 NKG 170 Score = 34.7 bits (78), Expect = 0.23 Identities = 22/81 (27%), Positives = 38/81 (46%) Frame = -3 Query: 405 FLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFYK 226 F +G ++ +V P V KSR+Q Q + +Y G + + R EG+ YK Sbjct: 210 FGIGFVSGTVGSVFNIPFDVAKSRIQGPQPVPGEI--KYRGCFKTMETVYREEGILALYK 267 Query: 225 GMGTKIVQSVFAASVLFMVKE 163 G+ K+++ V+ +V E Sbjct: 268 GLLPKVMRLGPGGGVMLLVYE 288 Score = 30.0 bits (66), Expect = 5.6 Identities = 15/42 (35%), Positives = 23/42 (54%), Gaps = 2/42 (4%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGLIPTLIMVCNP--SIQFMIYE 481 G + + VYRE GI +KGL+P +M P + ++YE Sbjct: 248 GCFKTMETVYREEGILALYKGLLPK-VMRLGPGGGVMLLVYE 288
>MFRN2_BRARE (Q7T292) Mitoferrin-2 (Mitochondrial iron transporter 2) (Solute| carrier family 25 member 28) Length = 376 Score = 38.9 bits (89), Expect = 0.012 Identities = 25/84 (29%), Positives = 45/84 (53%) Frame = -3 Query: 402 LLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFYKG 223 L GA+A + + +P+ VK+R+Q+ Q A+RY +DA+ +++R EG+ +G Sbjct: 82 LAGAVAGIMEHCLMFPIDCVKTRMQSLQP---EPAARYRNVMDALWRIMRTEGIWRPIRG 138 Query: 222 MGTKIVQSVFAASVLFMVKEELVK 151 + V + A ++ F E L K Sbjct: 139 LNITAVGAGPAHALYFACYERLKK 162
>UCP1_DICGR (Q8K404) Mitochondrial brown fat uncoupling protein 1 (UCP 1)| (Thermogenin) Length = 307 Score = 38.5 bits (88), Expect = 0.016 Identities = 25/78 (32%), Positives = 39/78 (50%) Frame = -3 Query: 414 MEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHG 235 ++ F G A L A ++T+PL K RLQ + E ++ RY G L I + + EG Sbjct: 15 VKTFSAGISACL-ADIITFPLDTAKVRLQIQGEGQTSSTIRYKGVLGTITTLAKTEGWPK 73 Query: 234 FYKGMGTKIVQSVFAASV 181 Y G+ I + + AS+ Sbjct: 74 LYSGLPAGIQRQISFASL 91 Score = 31.2 bits (69), Expect = 2.5 Identities = 28/103 (27%), Positives = 45/103 (43%) Frame = -3 Query: 504 SIQFMIYETLSKRLQSKRSGKRFPKKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQA 325 S++ +Y+T+ + S GK P T G + A + P VVK RLQA Sbjct: 90 SLRIGLYDTVQEYFSS---GKETPP---TLGNRISAGLMTGGVAVFIGQPTEVVKVRLQA 143 Query: 324 KQEIGRNAASRYTGTLDAILKMIRYEGLHGFYKGMGTKIVQSV 196 + + RYTGT +A + E +KG ++++V Sbjct: 144 QSHL-HGIKPRYTGTYNAYRIIATTESFSTLWKGTTPNLMRNV 185
>YDE9_SCHPO (Q10442) Putative mitochondrial carrier C12B10.09| Length = 345 Score = 38.1 bits (87), Expect = 0.020 Identities = 30/96 (31%), Positives = 43/96 (44%), Gaps = 3/96 (3%) Frame = -3 Query: 435 PKKNITAMEVF-LLGA--IAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAIL 265 P K +AM F LGA A L + +P+ +K+RLQAK +N Sbjct: 73 PSKRHSAMSFFEALGAGICAGLAVDLSLFPIDTLKTRLQAKGGFVKNG------------ 120 Query: 264 KMIRYEGLHGFYKGMGTKIVQSVFAASVLFMVKEEL 157 G HG Y+G+G+ +V S AS+ F E + Sbjct: 121 ------GFHGVYRGLGSILVGSAPGASLFFTTYENM 150
>MPCP_HUMAN (Q00325) Phosphate carrier protein, mitochondrial precursor (PTP)| (Solute carrier family 25 member 3) Length = 362 Score = 38.1 bits (87), Expect = 0.020 Identities = 43/159 (27%), Positives = 64/159 (40%), Gaps = 6/159 (3%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGLIPTLIMVCNPSI-QFMIYETLSKRLQSKRSGKRFPKKN 424 G +E G+ G KG PT + + +F YE K L S G+ Sbjct: 102 GIFNGFSVTLKEDGVRGLAKGWAPTFLGYSMQGLCKFGFYEVF-KVLYSNMLGEENTYLW 160 Query: 423 ITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTL-DAILKMIRYE 247 T++ + A A+ A + P+ K R+Q + Y TL DA KM + E Sbjct: 161 RTSLYL-AASASAEFFADIALAPMEAAKVRIQTQPG--------YANTLRDAAPKMYKEE 211 Query: 246 GLHGFYKGMG----TKIVQSVFAASVLFMVKEELVKFVI 142 GL FYKG+ +I ++ + E L KFV+ Sbjct: 212 GLKAFYKGVAPLWMRQIPYTMMKFACFERTVEALYKFVV 250
>GHC2_HUMAN (Q9H1K4) Mitochondrial glutamate carrier 2 (GC-2) (Glutamate/H(+)| symporter 2) (Solute carrier family 25 member 18) Length = 315 Score = 37.7 bits (86), Expect = 0.027 Identities = 18/63 (28%), Positives = 31/63 (49%) Frame = -3 Query: 396 GAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFYKGMG 217 G +A L +P+ + K+RLQ ++ + Y G +D ++K R EG G Y+G Sbjct: 15 GGVAGLVGVTCVFPIDLAKTRLQ-----NQHGKAMYKGMIDCLMKTARAEGFFGMYRGAA 69 Query: 216 TKI 208 + Sbjct: 70 VNL 72 Score = 31.6 bits (70), Expect = 1.9 Identities = 36/162 (22%), Positives = 67/162 (41%), Gaps = 20/162 (12%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGLIPTLIMVCNPSIQFMIYETLSKRLQSKRSGKRFPKKNI 421 G I + + R G G ++G L +V + +RL + +R K + Sbjct: 47 GMIDCLMKTARAEGFFGMYRGAAVNLTLVTPEKAIKLAANDFFRRLLMEDGMQRNLKMEM 106 Query: 420 TAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIG---RNAAS--------------- 295 A G A + VVT P+ ++K +LQ + + +AS Sbjct: 107 LA------GCGAGMCQVVVTCPMEMLKIQLQDAGRLAVHHQGSASAPSTSRSYTTGSAST 160 Query: 294 --RYTGTLDAILKMIRYEGLHGFYKGMGTKIVQSVFAASVLF 175 R + TL A +++R +GL G Y+G+G +++ + + + F Sbjct: 161 HRRPSATLIA-WELLRTQGLAGLYRGLGATLLRDIPFSIIYF 201
>UCP1_RABIT (P14271) Mitochondrial brown fat uncoupling protein 1 (UCP 1)| (Thermogenin) Length = 306 Score = 37.7 bits (86), Expect = 0.027 Identities = 25/89 (28%), Positives = 43/89 (48%) Frame = -3 Query: 414 MEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHG 235 +++F G A L A V+T+PL K R Q + E + RY G L I + + EG Sbjct: 15 VKIFSAGVAACL-ADVITFPLDTAKVRQQIQGEFPITSGIRYKGVLGTITTLAKTEGPLK 73 Query: 234 FYKGMGTKIVQSVFAASVLFMVKEELVKF 148 Y G+ + + + AS+ + + + +F Sbjct: 74 LYSGLPAGLQRQISFASLRIGLYDTVQEF 102 Score = 32.3 bits (72), Expect = 1.1 Identities = 27/103 (26%), Positives = 45/103 (43%) Frame = -3 Query: 504 SIQFMIYETLSKRLQSKRSGKRFPKKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQA 325 S++ +Y+T+ + S G+ P G +A + P VVK RLQA Sbjct: 90 SLRIGLYDTVQEFFTS---GEETPSLGSKISAGLTTGGVA----VFIGQPTEVVKVRLQA 142 Query: 324 KQEIGRNAASRYTGTLDAILKMIRYEGLHGFYKGMGTKIVQSV 196 + + RYTGT +A + E L +KG ++++V Sbjct: 143 QSHL-HGLKPRYTGTYNAYRIIATTESLTSLWKGTTPNLLRNV 184
>DIC_MOUSE (Q9QZD8) Mitochondrial dicarboxylate carrier (Solute carrier family| 25 member 10) Length = 287 Score = 37.4 bits (85), Expect = 0.035 Identities = 30/120 (25%), Positives = 49/120 (40%), Gaps = 1/120 (0%) Frame = -3 Query: 579 EVYRESGISGFWKGLIPTLIMVCNPSI-QFMIYETLSKRLQSKRSGKRFPKKNITAMEVF 403 +V R G + GL +L S+ +F IYET+ + G + Sbjct: 49 QVVRTDGFLALYNGLSASLCRQMTYSLTRFAIYETMRDYMTKDSQGP------LPFYNKV 102 Query: 402 LLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFYKG 223 LLG I+ L V P +V R+Q ++ + Y+ LD + ++ R E L + G Sbjct: 103 LLGGISGLTGGFVGTPADLVNVRMQNDMKLPPSQRRNYSHALDGLYRVAREESLRKLFSG 162 Score = 36.2 bits (82), Expect = 0.077 Identities = 22/80 (27%), Positives = 39/80 (48%) Frame = -3 Query: 396 GAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFYKGMG 217 G +A GA T+PL ++K LQ +QE+ R TG L+++R +G Y G+ Sbjct: 12 GGLASCGAACCTHPLDLLKVHLQTQQEV----KLRMTG---MALQVVRTDGFLALYNGLS 64 Query: 216 TKIVQSVFAASVLFMVKEEL 157 + + + + F + E + Sbjct: 65 ASLCRQMTYSLTRFAIYETM 84
>MPCP_BOVIN (P12234) Phosphate carrier protein, mitochondrial precursor (PTP)| (Solute carrier family 25 member 3) Length = 362 Score = 37.0 bits (84), Expect = 0.045 Identities = 43/149 (28%), Positives = 62/149 (41%), Gaps = 6/149 (4%) Frame = -3 Query: 570 RESGISGFWKGLIPTLIMVCNPSI-QFMIYETLSKRLQSKRSGKRFPKKNITAMEVFLLG 394 +E G G KG PT I + +F YE K L S G+ T++ + Sbjct: 112 KEDGFRGLAKGWAPTFIGYSLQGLCKFGFYEVF-KVLYSNMLGEENAYLWRTSLYL-AAS 169 Query: 393 AIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTL-DAILKMIRYEGLHGFYKGMG 217 A A+ A + P+ K R+Q + Y TL DA KM + EGL FYKG+ Sbjct: 170 ASAEFFADIALAPMEAAKVRIQTQPG--------YANTLRDAAPKMYKEEGLKAFYKGVA 221 Query: 216 ----TKIVQSVFAASVLFMVKEELVKFVI 142 +I ++ + E L KFV+ Sbjct: 222 PLWMRQIPYTMMKFACFERTVEALYKFVV 250 Score = 30.8 bits (68), Expect = 3.3 Identities = 33/134 (24%), Positives = 62/134 (46%), Gaps = 6/134 (4%) Frame = -3 Query: 588 AIREVYRESGISGFWKGLIPT-LIMVCNPSIQFMIYETLSKRL-----QSKRSGKRFPKK 427 A ++Y+E G+ F+KG+ P + + ++F +E + L RS P++ Sbjct: 203 AAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFERTVEALYKFVVPKPRSECSKPEQ 262 Query: 426 NITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYE 247 + F+ G IA + +V++P V S L +E G +A+ +LK + Sbjct: 263 LVV---TFVAGYIAGVFCAIVSHPADSVVSVL--NKEKGSSASE--------VLKRL--- 306 Query: 246 GLHGFYKGMGTKIV 205 G G +KG+ +I+ Sbjct: 307 GFRGVWKGLFARII 320 Score = 29.3 bits (64), Expect = 9.5 Identities = 13/36 (36%), Positives = 22/36 (61%), Gaps = 1/36 (2%) Frame = -3 Query: 579 EVYRESGISGFWKGLIPTLIMVCN-PSIQFMIYETL 475 EV + G G WKGL +IM+ ++Q+ IY+++ Sbjct: 301 EVLKRLGFRGVWKGLFARIIMIGTLTALQWFIYDSV 336
>ODC_MOUSE (Q8BZ09) Mitochondrial 2-oxodicarboxylate carrier (Solute carrier| family 25 member 21) Length = 298 Score = 37.0 bits (84), Expect = 0.045 Identities = 37/134 (27%), Positives = 59/134 (44%), Gaps = 6/134 (4%) Frame = -3 Query: 603 YGTIQ-AIREVYRESGISGFWKGLIPTLIM-VCNPSIQFMIYETLSKRL--QSKRSGKRF 436 Y T++ + + ++R G+ GF+KG+IP ++ +++F +E K L S G F Sbjct: 52 YRTVRGSFQMIFRTEGLFGFYKGIIPPILAETPKRAVKFSTFELYKKFLGYMSLSPGLTF 111 Query: 435 PKKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMI 256 + G + L VV P VVK LQ + RN T ++I Sbjct: 112 ----------LIAGLGSGLTEAVVVNPFEVVKVGLQ----VNRNLFKEQPSTFAYARQII 157 Query: 255 RYEGL--HGFYKGM 220 + EGL G KG+ Sbjct: 158 KKEGLGFQGLNKGL 171 Score = 35.8 bits (81), Expect = 0.10 Identities = 29/85 (34%), Positives = 42/85 (49%), Gaps = 1/85 (1%) Frame = -3 Query: 396 GAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMI-RYEGLHGFYKGM 220 G A L + +PL VVK+R Q ++ + + R T+ +MI R EGL GFYKG+ Sbjct: 19 GGSAGLVEICLMHPLDVVKTRFQVQRSVTDPQSYR---TVRGSFQMIFRTEGLFGFYKGI 75 Query: 219 GTKIVQSVFAASVLFMVKEELVKFV 145 I+ +V F E KF+ Sbjct: 76 IPPILAETPKRAVKFSTFELYKKFL 100 Score = 35.0 bits (79), Expect = 0.17 Identities = 34/149 (22%), Positives = 62/149 (41%), Gaps = 4/149 (2%) Frame = -3 Query: 597 TIQAIREVYRESGIS--GFWKGLIPTLIM--VCNPSIQFMIYETLSKRLQSKRSGKRFPK 430 T R++ ++ G+ G KGL TL + N + F Y + + S + Sbjct: 149 TFAYARQIIKKEGLGFQGLNKGLTATLGRHGIFN-MVYFGFYHNVKNIIPSSKD------ 201 Query: 429 KNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRY 250 + + F +G ++ +V P V KSR+Q Q + +Y + + R Sbjct: 202 PTLEFLRKFGIGFVSGTMGSVFNIPFDVAKSRIQGPQPVPGEI--KYRSCFKTMEMIYRE 259 Query: 249 EGLHGFYKGMGTKIVQSVFAASVLFMVKE 163 EG+ YKG+ K+++ V+ +V E Sbjct: 260 EGILALYKGLVPKVMRLGPGGGVMLLVYE 288
>ODC_PONPY (Q5RFB7) Mitochondrial 2-oxodicarboxylate carrier (Solute carrier| family 25 member 21) Length = 299 Score = 36.6 bits (83), Expect = 0.059 Identities = 33/132 (25%), Positives = 59/132 (44%), Gaps = 7/132 (5%) Frame = -3 Query: 594 IQAIREVYRESGISGFWKGLIPTLIM-VCNPSIQFMIYETLSKRLQSKRSGKRFPKKNIT 418 + + R +++ + GF+KG++P ++ +++F +E K L Sbjct: 57 VDSFRMIFQTERLFGFYKGILPPILAETPKRAVKFFTFEQYKKLL------------GYV 104 Query: 417 AMEVFLLGAIAKLGA----TVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRY 250 ++ L IA LG+ +V P VVK LQA RN ++ T+ ++I+ Sbjct: 105 SLSPALTFTIAGLGSGLTEAIVVNPFEVVKVGLQA----NRNTFAKQPSTVGYARQIIKK 160 Query: 249 E--GLHGFYKGM 220 E GL G KG+ Sbjct: 161 EGWGLQGLNKGL 172 Score = 36.2 bits (82), Expect = 0.077 Identities = 34/147 (23%), Positives = 66/147 (44%), Gaps = 2/147 (1%) Frame = -3 Query: 597 TIQAIREVYRESG--ISGFWKGLIPTLIMVCNPSIQFMIYETLSKRLQSKRSGKRFPKKN 424 T+ R++ ++ G + G KGL TL + M+Y +++ + P Sbjct: 150 TVGYARQIIKKEGWGLQGLNKGLTATL---GRHGVFNMVYFGFYYNVKNMIPVNKDP--T 204 Query: 423 ITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEG 244 + + F +G ++ A+V+ P V KSR+Q Q + +Y + + + EG Sbjct: 205 LEFLRKFGIGLLSGTIASVINIPFDVAKSRIQGPQPVPGEI--KYRTCFKTMATVYQEEG 262 Query: 243 LHGFYKGMGTKIVQSVFAASVLFMVKE 163 + YKG+ KI++ +V+ +V E Sbjct: 263 ILALYKGLLPKIMRLGPGGAVMLLVYE 289 Score = 33.1 bits (74), Expect = 0.66 Identities = 25/91 (27%), Positives = 41/91 (45%) Frame = -3 Query: 417 AMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLH 238 A + G A L + +PL VVK+R Q ++ + Y +D+ + + E L Sbjct: 13 ASRQIVAGGSAGLVEICLMHPLDVVKTRFQIQR--CATDPNSYKSLVDSFRMIFQTERLF 70 Query: 237 GFYKGMGTKIVQSVFAASVLFMVKEELVKFV 145 GFYKG+ I+ +V F E+ K + Sbjct: 71 GFYKGILPPILAETPKRAVKFFTFEQYKKLL 101
>UCP4_HUMAN (O95847) Mitochondrial uncoupling protein 4 (UCP 4) (Solute carrier| family 25 member 27) Length = 323 Score = 36.6 bits (83), Expect = 0.059 Identities = 30/127 (23%), Positives = 53/127 (41%), Gaps = 1/127 (0%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGLIPTLIMVCNPSI-QFMIYETLSKRLQSKRSGKRFPKKN 424 G A ++ E GI G W G +P + ++ Y+T+ L + N Sbjct: 172 GVHHAFAKILAEGGIRGLWAGWVPNIQRAALVNMGDLTTYDTVKHYLVLNTP----LEDN 227 Query: 423 ITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEG 244 I M L + L A+++ P V+KSR+ + + Y + D +++ ++ EG Sbjct: 228 I--MTHGLSSLCSGLVASILGTPADVIKSRIMNQPRDKQGRGLLYKSSTDCLIQAVQGEG 285 Query: 243 LHGFYKG 223 YKG Sbjct: 286 FMSLYKG 292 Score = 33.5 bits (75), Expect = 0.50 Identities = 26/94 (27%), Positives = 42/94 (44%), Gaps = 7/94 (7%) Frame = -3 Query: 405 FLLGAIAKLGATVVTYPLLVVKSRLQAKQEI-------GRNAASRYTGTLDAILKMIRYE 247 FLL A A + T+PL + K+RLQ + E G ++ Y G + L +I E Sbjct: 23 FLLSGCAATVAELATFPLDLTKTRLQMQGEAALARLGDGARESAPYRGMVRTALGIIEEE 82 Query: 246 GLHGFYKGMGTKIVQSVFAASVLFMVKEELVKFV 145 G ++G+ I + V + + E L + V Sbjct: 83 GFLKLWQGVTPAIYRHVVYSGGRMVTYEHLREVV 116
>GHC2_MOUSE (Q9DB41) Mitochondrial glutamate carrier 2 (GC-2) (Glutamate/H(+)| symporter 2) (Solute carrier family 25 member 18) (Fragment) Length = 312 Score = 36.6 bits (83), Expect = 0.059 Identities = 21/63 (33%), Positives = 32/63 (50%) Frame = -3 Query: 396 GAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFYKGMG 217 G IA L +P+ + K+RLQ +Q G++ Y G D ++K R EG G Y+G Sbjct: 12 GGIAGLVGVTCVFPIDLAKTRLQNQQ--GKDV---YRGMTDCLMKTARAEGFLGMYRGAA 66 Query: 216 TKI 208 + Sbjct: 67 VNL 69
>MFRN1_BRARE (Q287T7) Mitoferrin-1 (Mitochondrial iron transporter 1) (Solute| carrier family 25 member 37) (Protein frascati) Length = 332 Score = 36.6 bits (83), Expect = 0.059 Identities = 37/145 (25%), Positives = 63/145 (43%), Gaps = 3/145 (2%) Frame = -3 Query: 588 AIREVYRESGISGFWKGLIPTLIMVCNPS--IQFMIYETLSKRLQSK-RSGKRFPKKNIT 418 A++ + R G+ +GL T ++ P+ + F YE + + L ++G N Sbjct: 78 ALKRIVRTEGLLRPLRGLNIT-VLGAGPAHALYFACYERIKRSLSDVIQNGGNSHIANGV 136 Query: 417 AMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLH 238 A G++A + V P VVK R+Q S Y D +L + R EGL Sbjct: 137 A------GSVATVLHDAVMNPAEVVKQRMQMYN-------SPYRSLYDCVLMVSRKEGLA 183 Query: 237 GFYKGMGTKIVQSVFAASVLFMVKE 163 FY+ T++ ++ +V F+ E Sbjct: 184 AFYRSYSTQLTMNIPFQAVHFITYE 208 Score = 32.3 bits (72), Expect = 1.1 Identities = 21/80 (26%), Positives = 42/80 (52%) Frame = -3 Query: 396 GAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFYKGMG 217 GA+A + V YP+ VK+R+Q+ Q + ++Y A+ +++R EGL +G+ Sbjct: 40 GAVAGILEHTVMYPVDSVKTRMQSLQP---DPKAQYRSVYGALKRIVRTEGLLRPLRGLN 96 Query: 216 TKIVQSVFAASVLFMVKEEL 157 ++ + A ++ F E + Sbjct: 97 ITVLGAGPAHALYFACYERI 116 Score = 29.3 bits (64), Expect = 9.5 Identities = 14/41 (34%), Positives = 25/41 (60%), Gaps = 1/41 (2%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGLIPTLI-MVCNPSIQFMIYE 481 G + A+R VYR G+ F+KG+ +I + + +I + +YE Sbjct: 269 GMVNALRTVYRLGGVPAFFKGIQARVIYQMPSTAIAWSVYE 309
>YAD8_SCHPO (Q09834) Putative mitochondrial carrier C4G8.08| Length = 271 Score = 36.2 bits (82), Expect = 0.077 Identities = 32/124 (25%), Positives = 59/124 (47%), Gaps = 2/124 (1%) Frame = -3 Query: 573 YRESGISGFWKGLIPTLIMVCNPSIQFMIYETLSKRLQSKRSGKRFPKKNITAMEVFLLG 394 ++ + +++GL +L ++ + + LS +++KR K P A+ + G Sbjct: 38 FKTMPLKAYYRGLPISLTLITPATCLY-----LSTYVEAKRRFK--PSVGEGAILYSICG 90 Query: 393 AIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFYKG--M 220 A++ ++ V PL V+K+R Q Q+ ++ I + R EGL GFY+G M Sbjct: 91 MTAEVVSSFVWTPLEVIKARTQISQK---------GSVINTISTLARSEGLKGFYRGYWM 141 Query: 219 GTKI 208 G I Sbjct: 142 GVAI 145
>PET8_ASHGO (O60029) Putative mitochondrial carrier protein PET8| Length = 271 Score = 36.2 bits (82), Expect = 0.077 Identities = 24/88 (27%), Positives = 38/88 (43%) Frame = -3 Query: 420 TAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGL 241 T + + GA A VV +P+ +K+RLQAK N G Sbjct: 4 TFLASLVSGAAAGTSTDVVFFPIDTLKTRLQAKGGFFHNG------------------GY 45 Query: 240 HGFYKGMGTKIVQSVFAASVLFMVKEEL 157 G Y+G+G+ +V S AS+ F+ + + Sbjct: 46 RGIYRGLGSAVVASAPGASLFFVTYDSM 73
>GHC2_RAT (Q505J6) Mitochondrial glutamate carrier 2 (GC-2) (Glutamate/H(+)| symporter 2) (Solute carrier family 25 member 18) Length = 315 Score = 36.2 bits (82), Expect = 0.077 Identities = 21/63 (33%), Positives = 32/63 (50%) Frame = -3 Query: 396 GAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFYKGMG 217 G IA L +P+ + K+RLQ +Q G++ Y G D ++K R EG G Y+G Sbjct: 15 GGIAGLVGVTCVFPIDLAKTRLQNQQ--GKDV---YKGMTDCLVKTARAEGFLGMYRGAA 69 Query: 216 TKI 208 + Sbjct: 70 VNL 72
>YG5F_YEAST (P53320) Putative mitochondrial carrier YGR257C| Length = 366 Score = 35.4 bits (80), Expect = 0.13 Identities = 26/93 (27%), Positives = 44/93 (47%), Gaps = 1/93 (1%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGLIPTLIMVCNPS-IQFMIYETLSKRLQSKRSGKRFPKKN 424 GT++A ++ GI+ W+G+ TL+M + + F YE + +P N Sbjct: 104 GTLEAFTKIASVEGITSLWRGISLTLLMAIPANMVYFSGYEYIR---DVSPIASTYPTLN 160 Query: 423 ITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQA 325 GAIA++ A PL +VK++LQ+ Sbjct: 161 -----PLFCGAIARVFAATSIAPLELVKTKLQS 188 Score = 31.2 bits (69), Expect = 2.5 Identities = 12/45 (26%), Positives = 27/45 (60%) Frame = -3 Query: 309 RNAASRYTGTLDAILKMIRYEGLHGFYKGMGTKIVQSVFAASVLF 175 +N++ ++ GTL+A K+ EG+ ++G+ ++ ++ A V F Sbjct: 96 KNSSLKFNGTLEAFTKIASVEGITSLWRGISLTLLMAIPANMVYF 140
>DIC1_YEAST (Q06143) Mitochondrial dicarboxylate transporter (Dicarboxylate| carrier 1) (DTP) Length = 298 Score = 35.4 bits (80), Expect = 0.13 Identities = 30/137 (21%), Positives = 54/137 (39%), Gaps = 7/137 (5%) Frame = -3 Query: 585 IREVYRESGISGFWKGLIPTLIMVCN-PSIQFMIYETLSKRLQSKRSGKRFPKKNITAME 409 + + G+ G + GL ++ C +++F Y+ L + + P++ +T M Sbjct: 55 LESILANEGVVGLYSGLSAAVLRQCTYTTVRFGAYDLLKENV--------IPREQLTNMA 106 Query: 408 VFL-----LGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYE- 247 L GAI L VV R+Q + Y +D + K+ RYE Sbjct: 107 YLLPCSMFSGAIGGLAGNFAD----VVNIRMQNDSALEAAKRRNYKNAIDGVYKIYRYEG 162 Query: 246 GLHGFYKGMGTKIVQSV 196 GL + G +V+ + Sbjct: 163 GLKTLFTGWKPNMVRGI 179 Score = 32.3 bits (72), Expect = 1.1 Identities = 26/86 (30%), Positives = 44/86 (51%), Gaps = 5/86 (5%) Frame = -3 Query: 396 GAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILK-MIRYEGLHGFYKGM 220 G A + AT+VT+PL + K RLQ AA TL +L+ ++ EG+ G Y G+ Sbjct: 20 GGAAGIFATMVTHPLDLAKVRLQ--------AAPMPKPTLFRMLESILANEGVVGLYSGL 71 Query: 219 GTKIVQSVFAASVLF----MVKEELV 154 +++ +V F ++KE ++ Sbjct: 72 SAAVLRQCTYTTVRFGAYDLLKENVI 97
>MTCH1_MOUSE (Q791T5) Mitochondrial carrier homolog 1 (Mitochondrial| carrier-like protein 1) Length = 389 Score = 35.4 bits (80), Expect = 0.13 Identities = 33/126 (26%), Positives = 63/126 (50%), Gaps = 7/126 (5%) Frame = -3 Query: 576 VYRESGISGFWKGLIPTLIM-----VCNPSIQFMIYETLSKRLQSKRSGKRFPKKNI--T 418 + + G G ++GL P L+ V S++ + +++ +K K KK + T Sbjct: 139 IVQVDGKIGLFRGLSPRLMSNALSTVTRGSMKKVFPPDEMEQVSNKDDMKTSLKKVVKET 198 Query: 417 AMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLH 238 + E+ + + + ++ +PL V+ R Q +GR A +Y+G L +I K+ + EGL Sbjct: 199 SYEMMM-----QCVSRMLAHPLHVISMRCMV-QFVGREA--KYSGVLSSIGKIFKEEGLL 250 Query: 237 GFYKGM 220 GF+ G+ Sbjct: 251 GFFVGL 256 Score = 32.0 bits (71), Expect = 1.5 Identities = 25/101 (24%), Positives = 48/101 (47%), Gaps = 15/101 (14%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGLIPTL------IMVCNPSIQFM--------IYETLSKRL 463 G + +I ++++E G+ GF+ GLIP L + CN F+ + +T Sbjct: 235 GVLSSIGKIFKEEGLLGFFVGLIPHLLGDVVFLWGCNLLAHFINAYLVDDSVSDTPGGLG 294 Query: 462 QSKRSGKRFPKK-NITAMEVFLLGAIAKLGATVVTYPLLVV 343 + G +F + I + F++G + +++TYP L+V Sbjct: 295 NDQNPGSQFSQALAIRSYTKFVMG----IAVSMLTYPFLLV 331
>MTCH1_HUMAN (Q9NZJ7) Mitochondrial carrier homolog 1 (Presenilin-associated| protein) Length = 389 Score = 35.4 bits (80), Expect = 0.13 Identities = 35/128 (27%), Positives = 64/128 (50%), Gaps = 9/128 (7%) Frame = -3 Query: 576 VYRESGISGFWKGLIPTLIM-----VCNPSIQFMI----YETLSKRLQSKRSGKRFPKKN 424 + + G G ++GL P L+ V S++ + E +S + K S K+ K+ Sbjct: 139 IVQVDGKIGLFRGLSPRLMSNALSTVTRGSMKKVFPPDEIEQVSNKDDMKTSLKKVVKE- 197 Query: 423 ITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEG 244 T+ E+ + + + ++ +PL V+ R Q +GR A +Y+G L +I K+ + EG Sbjct: 198 -TSYEMMM-----QCVSRMLAHPLHVISMRCMV-QFVGREA--KYSGVLSSIGKIFKEEG 248 Query: 243 LHGFYKGM 220 L GF+ G+ Sbjct: 249 LLGFFVGL 256 Score = 32.0 bits (71), Expect = 1.5 Identities = 25/101 (24%), Positives = 48/101 (47%), Gaps = 15/101 (14%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFWKGLIPTL------IMVCNPSIQFM--------IYETLSKRL 463 G + +I ++++E G+ GF+ GLIP L + CN F+ + +T Sbjct: 235 GVLSSIGKIFKEEGLLGFFVGLIPHLLGDVVFLWGCNLLAHFINAYLVDDSVSDTPGGLG 294 Query: 462 QSKRSGKRFPKK-NITAMEVFLLGAIAKLGATVVTYPLLVV 343 + G +F + I + F++G + +++TYP L+V Sbjct: 295 NDQNPGSQFSQALAIRSYTKFVMG----IAVSMLTYPFLLV 331
>MRS3_YEAST (P10566) Mitochondrial RNA-splicing protein MRS3| Length = 314 Score = 35.4 bits (80), Expect = 0.13 Identities = 37/153 (24%), Positives = 63/153 (41%), Gaps = 3/153 (1%) Frame = -3 Query: 594 IQAIREVYRESGISGFWKGLIPTLIMVCNPS--IQFMIYETLSKRL-QSKRSGKRFPKKN 424 + I + G WKG + ++I+ P+ + F YE K L S + P K Sbjct: 75 LSQISHISTSEGTLALWKG-VQSVILGAGPAHAVYFGTYEFCKKNLIDSSDTQTHHPFKT 133 Query: 423 ITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEG 244 + GA A + + P +K R+Q +AS + T ++ + EG Sbjct: 134 AIS------GACATTASDALMNPFDTIKQRIQLN-----TSASVWQTTK----QIYQSEG 178 Query: 243 LHGFYKGMGTKIVQSVFAASVLFMVKEELVKFV 145 L FY T +V ++ A+ F++ E KF+ Sbjct: 179 LAAFYYSYPTTLVMNIPFAAFNFVIYESSTKFL 211
>PET8_YEAST (P38921) Putative mitochondrial carrier protein PET8| Length = 284 Score = 34.7 bits (78), Expect = 0.23 Identities = 23/77 (29%), Positives = 34/77 (44%) Frame = -3 Query: 402 LLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFYKG 223 L GA A +V +P+ +K+RLQAK N G G Y+G Sbjct: 9 LSGAAAGTSTDLVFFPIDTIKTRLQAKGGFFANG------------------GYKGIYRG 50 Query: 222 MGTKIVQSVFAASVLFM 172 +G+ +V S AS+ F+ Sbjct: 51 LGSAVVASAPGASLFFI 67
>MPCP_CAEEL (P40614) Phosphate carrier protein, mitochondrial precursor (PTP)| Length = 340 Score = 33.9 bits (76), Expect = 0.38 Identities = 32/129 (24%), Positives = 57/129 (44%), Gaps = 5/129 (3%) Frame = -3 Query: 576 VYRESGISGFWKGLIPT-LIMVCNPSIQFMIYETLSKRLQSKRSGKRFPKKNITAME--- 409 +Y+ G++GF+KGL P + + ++F +E + L K P+ + E Sbjct: 185 IYKAEGLTGFYKGLPPLWMRQIPYTMMKFACFEKTVEALYQYVVPK--PRAECSKAEQLV 242 Query: 408 -VFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGF 232 F+ G IA + +V++P V S+L + T ILK + G G Sbjct: 243 VTFVAGYIAGVFCAIVSHPADTVVSKLNQDSQ----------ATAGGILKKL---GFAGV 289 Query: 231 YKGMGTKIV 205 +KG+ +I+ Sbjct: 290 WKGLVPRII 298 Score = 33.5 bits (75), Expect = 0.50 Identities = 14/43 (32%), Positives = 27/43 (62%), Gaps = 1/43 (2%) Frame = -3 Query: 576 VYRESGISGFWKGLIPTLIMVCN-PSIQFMIYETLSKRLQSKR 451 + ++ G +G WKGL+P +IM+ ++Q+ IY+++ L R Sbjct: 280 ILKKLGFAGVWKGLVPRIIMIGTLTALQWFIYDSVKVALNLPR 322
>GLR27_ARATH (Q8LGN0) Glutamate receptor 2.7 precursor (Ligand-gated ion channel| 2.7) Length = 949 Score = 33.5 bits (75), Expect = 0.50 Identities = 32/118 (27%), Positives = 52/118 (44%), Gaps = 11/118 (9%) Frame = -3 Query: 474 SKRLQSKRSG--KRFPKK-NITAMEVFLLGAIAKLGATVVTYPLLVVKSRL--------Q 328 SK+L++ R K FPKK N M +F L A + A + +KS Sbjct: 292 SKKLKNFRLRWEKMFPKKGNDEEMNIFALRAYDSITALAMAVEKTNIKSLRYDHPIASGN 351 Query: 327 AKQEIGRNAASRYTGTLDAILKMIRYEGLHGFYKGMGTKIVQSVFAASVLFMVKEELV 154 K +G SRY +L L +R+ GL G ++ + ++ SVF + +E ++ Sbjct: 352 NKTNLGTLGVSRYGPSLLKALSNVRFNGLAGEFELINGQLESSVFDVINIIGSEERII 409
>YHM2_YEAST (Q04013) Mitochondrial DNA replication protein YHM2| Length = 314 Score = 32.3 bits (72), Expect = 1.1 Identities = 35/153 (22%), Positives = 63/153 (41%), Gaps = 5/153 (3%) Frame = -3 Query: 606 PYGTIQAIREVYRESGISGFWKGLIPTLI-MVCNPSIQFMIYETLSKRLQSKRSGKRFPK 430 P + + +Y++ GI G KG+ I + N +F + + ++ K +GK Sbjct: 152 PQSSWSVFKNIYKKEGIRGINKGVNAVAIRQMTNWGSRFGLSRLVEDGIR-KITGKTNKD 210 Query: 429 KNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRY 250 + E A+ G + P+ V++ +Q+K+E + G + + Sbjct: 211 DKLNPFEKIGASALGG-GLSAWNQPIEVIRVEMQSKKEDPNRPKNLTVG--KTFKYIYQS 267 Query: 249 EGLHGFYKG----MGTKIVQSVFAASVLFMVKE 163 GL G Y+G +G I Q+VF M KE Sbjct: 268 NGLKGLYRGVTPRIGLGIWQTVFMVGFGDMAKE 300
>GLR21_ARATH (O04660) Glutamate receptor 2.1 precursor (Ligand-gated ion channel| 2.1) (AtGLR3) Length = 901 Score = 32.3 bits (72), Expect = 1.1 Identities = 29/107 (27%), Positives = 51/107 (47%), Gaps = 9/107 (8%) Frame = -3 Query: 486 YETLSKRLQSKRSG--KRFPKKNITAMEVF-------LLGAIAKLGATVVTYPLLVVKSR 334 Y SK L++ RS KRFP ++ ++ L AI + G + +T+ + K Sbjct: 283 YVPRSKELENFRSRWTKRFPISDLNVYGLWAYDATTALALAIEEAGTSNLTFVKMDAKRN 342 Query: 333 LQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFYKGMGTKIVQSVF 193 + Q +G S+Y L L +R++GL G ++ + ++ SVF Sbjct: 343 VSELQGLG---VSQYGPKLLQTLSRVRFQGLAGDFQFINGELQPSVF 386
>MFRN1_BOVIN (Q3ZBJ8) Mitoferrin-1 (Mitochondrial iron transporter 1) (Solute| carrier family 25 member 37) Length = 171 Score = 32.0 bits (71), Expect = 1.5 Identities = 22/80 (27%), Positives = 41/80 (51%) Frame = -3 Query: 396 GAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFYKGMG 217 GA+A + V YP+ VK+R+Q+ + + + YT A+ K+IR EG +G+ Sbjct: 52 GAMAGILEHSVMYPVDSVKTRMQS---LNPDPKAHYTSVYGALKKIIRTEGFWRPLRGLN 108 Query: 216 TKIVQSVFAASVLFMVKEEL 157 ++ + A ++ F E + Sbjct: 109 VMMMGAGPAHAMYFACYENM 128
>LEU5_YEAST (P38702) Mitochondrial carrier protein LEU5| Length = 357 Score = 31.6 bits (70), Expect = 1.9 Identities = 28/149 (18%), Positives = 60/149 (40%), Gaps = 18/149 (12%) Frame = -3 Query: 549 FWKGLIPTLI-MVCNPSIQFMIYETLSKRLQSKRSG-------------KRFPKKNITAM 412 F++G +PT++ M+ + F ++ L L+S +R KK + Sbjct: 203 FYRGYVPTVLGMIPYAGVSFFAHDLLHDVLKSPFFAPYSVLELSEDDELERVQKKQRRPL 262 Query: 411 EVF---LLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMI-RYEG 244 + + G +A + + YP +++ RLQ + ++ I +I + G Sbjct: 263 RTWAELISGGLAGMASQTAAYPFEIIRRRLQVSALSPKTMYDHKFQSISEIAHIIFKERG 322 Query: 243 LHGFYKGMGTKIVQSVFAASVLFMVKEEL 157 + GF+ G+ ++ + F V E + Sbjct: 323 VRGFFVGLSIGYIKVTPMVACSFFVYERM 351
>MOEA1_MYCTU (O05577) Molybdopterin biosynthesis protein moeA 1| Length = 426 Score = 30.8 bits (68), Expect = 3.3 Identities = 15/65 (23%), Positives = 30/65 (46%), Gaps = 3/65 (4%) Frame = -3 Query: 600 GTIQAIREVYRESGISGFW---KGLIPTLIMVCNPSIQFMIYETLSKRLQSKRSGKRFPK 430 G ++ +R + GF + +PT ++ NP +++E + + L GKR P Sbjct: 282 GEMEVVRVAMHPGSVQGFGQLGRDGVPTFLLPANPVSALVVFEVMVRPLIRLSLGKRHPM 341 Query: 429 KNITA 415 + I + Sbjct: 342 RRIVS 346
>YHM1_YEAST (P38988) Putative mitochondrial carrier protein YHM1/SHM1| Length = 300 Score = 30.4 bits (67), Expect = 4.2 Identities = 18/67 (26%), Positives = 36/67 (53%) Frame = -3 Query: 405 FLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFYK 226 F+ + + +V+ PL V+K+R+Q RN + +G L + ++ EG+ F+K Sbjct: 214 FISSIVGACSSLIVSAPLDVIKTRIQ-----NRNFDNPESG-LRIVKNTLKNEGVTAFFK 267 Query: 225 GMGTKIV 205 G+ K++ Sbjct: 268 GLTPKLL 274
>MNCP_OXYFA (P15798) Macronuclear solute carrier homolog CR-MSC| Length = 371 Score = 30.0 bits (66), Expect = 5.6 Identities = 16/49 (32%), Positives = 27/49 (55%) Frame = -3 Query: 393 AIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYE 247 A+A TVV+ P ++++RL + + N Y G +D K+I+YE Sbjct: 225 AVAVAIGTVVSMPFDMIRTRLHTMRPLP-NGQMPYNGMIDCFNKIIKYE 272
>MIAA_BARQU (Q6FZ96) tRNA delta(2)-isopentenylpyrophosphate transferase (EC| 2.5.1.8) (IPP transferase) (Isopentenyl-diphosphate:tRNA isopentenyltransferase) (IPTase) (IPPT) Length = 295 Score = 30.0 bits (66), Expect = 5.6 Identities = 15/46 (32%), Positives = 23/46 (50%) Frame = -2 Query: 496 VYDI*NAVKASPVEAVWKAIPQEEHHCYGGIFIRCNSKAGSYCCDL 359 VYD+ N + A P EA +P H+ YG + + G + CD+ Sbjct: 40 VYDVLNILTARPTEADTAIVP---HYLYGYVSPALHYSVGQWLCDV 82
>PIC2_YEAST (P40035) Mitochondrial phosphate carrier protein 2 (Phosphate| transport protein 2) (PTP 2) (mPic 2) (Pi carrier isoform 2) Length = 300 Score = 29.6 bits (65), Expect = 7.2 Identities = 23/66 (34%), Positives = 28/66 (42%), Gaps = 1/66 (1%) Frame = -3 Query: 399 LGAIAKLGATVVTY-PLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFYKG 223 LG I G T + PL +VK RLQ ++ YT L K+I EG Y G Sbjct: 23 LGGIIACGPTHSSITPLDLVKCRLQVNPKL-------YTSNLQGFRKIIANEGWKKVYTG 75 Query: 222 MGTKIV 205 G V Sbjct: 76 FGATFV 81
>MNCP_OXYTR (Q27151) Macronuclear solute carrier homolog CR-MSC| Length = 371 Score = 29.3 bits (64), Expect = 9.5 Identities = 16/49 (32%), Positives = 26/49 (53%) Frame = -3 Query: 393 AIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYE 247 A+A TVV+ P ++++RL + + N Y G D K+I+YE Sbjct: 225 AVAVAIGTVVSMPFDMIRTRLHTMRPLP-NGQMPYNGMFDCFNKIIKYE 272
>MPCP_CHOFU (O61703) Phosphate carrier protein, mitochondrial precursor| (Phosphate transport protein) (PTP) Length = 349 Score = 29.3 bits (64), Expect = 9.5 Identities = 14/38 (36%), Positives = 23/38 (60%), Gaps = 1/38 (2%) Frame = -3 Query: 561 GISGFWKGLIPTLIMVCN-PSIQFMIYETLSKRLQSKR 451 G +G WKGL P +IM+ ++Q+ IY+ + L+ R Sbjct: 292 GFAGVWKGLGPRIIMIGTLTALQWFIYDAVKVWLRMPR 329
>MIAA_STAAS (Q6G9R0) tRNA delta(2)-isopentenylpyrophosphate transferase (EC| 2.5.1.8) (IPP transferase) (Isopentenyl-diphosphate:tRNA isopentenyltransferase) (IPTase) (IPPT) Length = 311 Score = 29.3 bits (64), Expect = 9.5 Identities = 23/100 (23%), Positives = 42/100 (42%), Gaps = 6/100 (6%) Frame = -3 Query: 372 TVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFYKGMGTKIVQSVF 193 TV L +VK +L A + + Y DA + E +H + G + ++ Sbjct: 121 TVTPAQLSIVKQKLSALEHLDNQQLHDYLAQFDA----VSAENIHPNNRQRGLRAIEYYL 176 Query: 192 AASVLFMVKEELVKF------VILLVARSRTLLLTRSNKR 91 L ++++ +F ++L + SR L +R NKR Sbjct: 177 KTKKLLSNRKKVQQFTENYDTLLLGIEMSRKTLYSRINKR 216 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 82,024,701 Number of Sequences: 219361 Number of extensions: 1562520 Number of successful extensions: 4296 Number of sequences better than 10.0: 186 Number of HSP's better than 10.0 without gapping: 3830 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 4116 length of database: 80,573,946 effective HSP length: 107 effective length of database: 57,102,319 effective search space used: 5481822624 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
