ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | FLbaf98k19 |
|---|---|
| Clone Library Name | barley_pub |
>P54873:HMCS_ARATH Hydroxymethylglutaryl-CoA synthase - Arabidopsis thaliana (Mouse-ear| cress) Length = 461 Score = 723 bits (1867), Expect = 0.0 Identities = 352/468 (75%), Positives = 407/468 (86%), Gaps = 2/468 (0%) Frame = +3 Query: 129 KDVGILAMDMYFPPTCVQQEALEVHDGASKGKYTIGLGQDCMAFCSEVEDVISMSLTVVK 308 K+VGILAMD+YFPPTCVQQEALE HDGASKGKYTIGLGQDC+AFC+E+EDVISMS V Sbjct: 3 KNVGILAMDIYFPPTCVQQEALEAHDGASKGKYTIGLGQDCLAFCTELEDVISMSFNAVT 62 Query: 309 SLLEKYHIDPKLIGRLEVGSETVIDKSKSIKTWLMQIFEESGNTDIEGVDSSNACYGGTA 488 SL EKY IDP IGRLEVGSETVIDKSKSIKT+LMQ+FE+ GNTD+EGVDS+NACYGGTA Sbjct: 63 SLFEKYKIDPNQIGRLEVGSETVIDKSKSIKTFLMQLFEKCGNTDVEGVDSTNACYGGTA 122 Query: 489 ALLNCVNWVESRCWDGRYGLVVCTDSAVYAEGPARPTGGAAAIAMLIGPNAPISFESKYR 668 ALLNCVNWVES WDGRYGLV+CTDSAVYAEGPARPTGGAAAIAMLIGP+API FESK R Sbjct: 123 ALLNCVNWVESNSWDGRYGLVICTDSAVYAEGPARPTGGAAAIAMLIGPDAPIVFESKLR 182 Query: 669 ASHMAHVYDFYKPDLASEYPVVDGKLSQTCYLMALDSCYRQYCAKYEKLVGEQFSISDAD 848 ASHMAHVYDFYKP+LASEYPVVDGKLSQTCYLMALDSCY+ C K+EK+ G++FSI+DAD Sbjct: 183 ASHMAHVYDFYKPNLASEYPVVDGKLSQTCYLMALDSCYKHLCNKFEKIEGKEFSINDAD 242 Query: 849 YCVFHSPYNKLVQKSFARLYFNDFMRNCSSVDNDAKEKLQPFANLTSEESYQSRDLEKGS 1028 Y VFHSPYNKLVQKSFARL +NDF+RN SS+D AKEK P+++LT +ESYQSRDLEK S Sbjct: 243 YIVFHSPYNKLVQKSFARLLYNDFLRNASSIDEAAKEKFTPYSSLTLDESYQSRDLEKVS 302 Query: 1029 QQLAKHLYDIKVQPSTLLPKQIGNMYTASLYAALASVIYNKHASLNGQRIVMFSYGSGLT 1208 QQ+AK YD KVQP+TL+PK++GNMYTASLYAA AS+I+ KH L G+R+VMFSYGSG T Sbjct: 303 QQIAKPFYDAKVQPTTLIPKEVGNMYTASLYAAFASLIHKKHNDLAGKRVVMFSYGSGST 362 Query: 1209 STMFSFKLNEGQHPFSLTNIASVLDVAAKLESRHVTSPEKFIDTLKLMEHRYGAKDFETS 1388 +TMFS +LN+ + PFS++NIASV+DV KL++RH +PEKF++T+KLMEHRYGAKDF T+ Sbjct: 363 ATMFSLRLNDNKPPFSISNIASVMDVGGKLKARHEYAPEKFVETMKLMEHRYGAKDFVTT 422 Query: 1389 KD--ISLLPPGTFYLTKVDSMYRRFYEKKTDGIVDGKIKCSNGIANGH 1526 K+ I LL PGT+YL +VDS+YRRFY KK + DG +ANGH Sbjct: 423 KEGIIDLLAPGTYYLKEVDSLYRRFYGKKGE---DG------SVANGH 461
>P54961:HMCS1_BLAGE Hydroxymethylglutaryl-CoA synthase 1 - Blattella germanica (German| cockroach) Length = 453 Score = 452 bits (1163), Expect = e-126 Identities = 230/448 (51%), Positives = 307/448 (68%), Gaps = 3/448 (0%) Frame = +3 Query: 132 DVGILAMDMYFPPTCVQQEALEVHDGASKGKYTIGLGQDCMAFCSEVEDVISMSLTVVKS 311 DVGI+A+++ FP V Q LEV+D S GKYT+GLGQ M FC++ ED+ S+ LTVV Sbjct: 5 DVGIVALELIFPSQYVDQVDLEVYDNVSAGKYTVGLGQARMGFCTDREDINSLCLTVVSR 64 Query: 312 LLEKYHIDPKLIGRLEVGSETVIDKSKSIKTWLMQIFEESGNTDIEGVDSSNACYGGTAA 491 L+E++ I IGRLEVG+ET++DKSKS+KT LMQ+F++ NTDIEGVD+ NACYGGT+A Sbjct: 65 LMERWSIPYSQIGRLEVGTETLLDKSKSVKTVLMQLFKD--NTDIEGVDTVNACYGGTSA 122 Query: 492 LLNCVNWVESRCWDGRYGLVVCTDSAVYAEGPARPTGGAAAIAMLIGPNAPISFESKYRA 671 L N ++WVES WDGRY LVV D AVYA+G ARPTGGA A+AML+G NAP+ F+ R+ Sbjct: 123 LFNAISWVESSSWDGRYALVVAGDIAVYAKGSARPTGGAGAVAMLVGANAPLVFDRGVRS 182 Query: 672 SHMAHVYDFYKPDLASEYPVVDGKLSQTCYLMALDSCYRQYCAKYEKLVGEQFSISDADY 851 SHM H YDFYKPDL+S YP VDGKLS CYL ALD CY+ YC+K +K +GE+F I D Sbjct: 183 SHMQHAYDFYKPDLSSLYPTVDGKLSIQCYLSALDHCYQLYCSKIQKQLGEKFDIERLDA 242 Query: 852 CVFHSPYNKLVQKSFARLYFNDFMRNCSSVDNDAKEKLQPFANLTSEESYQSRDLEKGSQ 1031 +FH+PY KLVQKS ARL NDF+R L+ + E++Y R++EK Sbjct: 243 VLFHAPYCKLVQKSLARLVLNDFVRASEEERTTKYSSLEALKGVKLEDTYFDREVEKAVM 302 Query: 1032 QLAKHLYDIKVQPSTLLPKQIGNMYTASLYAALASVIYNKHA-SLNGQRIVMFSYGSGLT 1208 +K++++ K +PS LL Q+GNMYT SLY L S++ +K A L G+R+ +FSYGSGL Sbjct: 303 TYSKNMFEEKTKPSLLLANQVGNMYTPSLYGGLVSLLVSKSAQELAGKRVALFSYGSGLA 362 Query: 1209 STMFSFKL-NEGQHPFSLTNIASVLD-VAAKLESRHVTSPEKFIDTLKLMEHRYGAKDFE 1382 S+MFS ++ ++ SL + S L + +L+ RH SPE+F T++ EH + + Sbjct: 363 SSMFSLRISSDASAKSSLQRLVSNLSHIKPQLDLRHKVSPEEFAQTMETREHNHHKAPYT 422 Query: 1383 TSKDISLLPPGTFYLTKVDSMYRRFYEK 1466 I +L PGT+YL VDS+YRR Y++ Sbjct: 423 PEGSIDVLFPGTWYLESVDSLYRRSYKQ 450
>Q5R7Z9:HMCS1_PONPY Hydroxymethylglutaryl-CoA synthase, cytoplasmic - Pongo pygmaeus| (Orangutan) Length = 520 Score = 446 bits (1146), Expect = e-124 Identities = 227/455 (49%), Positives = 313/455 (68%), Gaps = 8/455 (1%) Frame = +3 Query: 129 KDVGILAMDMYFPPTCVQQEALEVHDGASKGKYTIGLGQDCMAFCSEVEDVISMSLTVVK 308 KDVGI+A+++YFP V Q LE +DG + GKYTIGLGQ M FC++ ED+ S+ +TVV+ Sbjct: 15 KDVGIVALEIYFPSQYVDQAELEKYDGVAAGKYTIGLGQAKMGFCTDREDINSLCMTVVQ 74 Query: 309 SLLEKYHIDPKLIGRLEVGSETVIDKSKSIKTWLMQIFEESGNTDIEGVDSSNACYGGTA 488 +L+E+ ++ IGRLEVG+ET+IDKSKS+KT LMQ+FEESGNTDIEG+D++NACYGGTA Sbjct: 75 NLMERNNLSYDCIGRLEVGTETIIDKSKSVKTNLMQLFEESGNTDIEGIDTTNACYGGTA 134 Query: 489 ALLNCVNWVESRCWDGRYGLVVCTDSAVYAEGPARPTGGAAAIAMLIGPNAPISFESKYR 668 A+ N VNW+ES WDGRY LVV D AVYA G ARPTGG A+A+LIGPNAP+ FE R Sbjct: 135 AVFNAVNWIESSSWDGRYALVVAGDIAVYATGNARPTGGVGAVALLIGPNAPLIFERGLR 194 Query: 669 ASHMAHVYDFYKPDLASEYPVVDGKLSQTCYLMALDSCYRQYC----AKYEKLVGEQ-FS 833 +HM H YDFYKPD+ SEYP+VDGKLS CYL ALD CY YC A+++K ++ F+ Sbjct: 195 GTHMQHAYDFYKPDMLSEYPIVDGKLSIQCYLSALDRCYSVYCKKIRAQWQKEGNDKDFT 254 Query: 834 ISDADYCVFHSPYNKLVQKSFARLYFNDFMRNCSSVDNDAKEKLQPFANLTSEESYQSRD 1013 ++D + +FHSPY KLVQKS AR+ NDF+ + + N L+ F ++ E++Y RD Sbjct: 255 LNDFGFMIFHSPYCKLVQKSLARMLLNDFLNDQNRDKNSIYSGLEAFGDVKLEDTYFDRD 314 Query: 1014 LEKGSQQLAKHLYDIKVQPSTLLPKQIGNMYTASLYAALASVIYN-KHASLNGQRIVMFS 1190 +EK + + L+ K + S L+ Q GNMYT+S+Y +LASV+ L G+RI +FS Sbjct: 315 VEKAFMKASSELFSQKTKASLLVSNQNGNMYTSSVYGSLASVLAQYSPQQLAGKRIGVFS 374 Query: 1191 YGSGLTSTMFSFKLNEGQHPFSLTN--IASVLDVAAKLESRHVTSPEKFIDTLKLMEHRY 1364 YGSGL +T++S K+ + P S + AS+ D+ ++L+SR +P+ F + +KL E + Sbjct: 375 YGSGLAATLYSLKVTQDATPGSALDKITASLCDLKSRLDSRTGVAPDVFAENMKLREDTH 434 Query: 1365 GAKDFETSKDISLLPPGTFYLTKVDSMYRRFYEKK 1469 ++ I L GT+YL +VD +RR Y ++ Sbjct: 435 HLVNYIPQGSIDSLFEGTWYLVRVDEKHRRTYARR 469
>Q01581:HMCS1_HUMAN Hydroxymethylglutaryl-CoA synthase, cytoplasmic - Homo sapiens| (Human) Length = 520 Score = 445 bits (1145), Expect = e-124 Identities = 227/455 (49%), Positives = 312/455 (68%), Gaps = 8/455 (1%) Frame = +3 Query: 129 KDVGILAMDMYFPPTCVQQEALEVHDGASKGKYTIGLGQDCMAFCSEVEDVISMSLTVVK 308 KDVGI+A+++YFP V Q LE +DG GKYTIGLGQ M FC++ ED+ S+ +TVV+ Sbjct: 15 KDVGIVALEIYFPSQYVDQAELEKYDGVDAGKYTIGLGQAKMGFCTDREDINSLCMTVVQ 74 Query: 309 SLLEKYHIDPKLIGRLEVGSETVIDKSKSIKTWLMQIFEESGNTDIEGVDSSNACYGGTA 488 +L+E+ ++ IGRLEVG+ET+IDKSKS+KT LMQ+FEESGNTDIEG+D++NACYGGTA Sbjct: 75 NLMERNNLSYDCIGRLEVGTETIIDKSKSVKTNLMQLFEESGNTDIEGIDTTNACYGGTA 134 Query: 489 ALLNCVNWVESRCWDGRYGLVVCTDSAVYAEGPARPTGGAAAIAMLIGPNAPISFESKYR 668 A+ N VNW+ES WDGRY LVV D AVYA G ARPTGG A+A+LIGPNAP+ FE R Sbjct: 135 AVFNAVNWIESSSWDGRYALVVAGDIAVYATGNARPTGGVGAVALLIGPNAPLIFERGLR 194 Query: 669 ASHMAHVYDFYKPDLASEYPVVDGKLSQTCYLMALDSCYRQYC----AKYEKLVGEQ-FS 833 +HM H YDFYKPD+ SEYP+VDGKLS CYL ALD CY YC A+++K ++ F+ Sbjct: 195 GTHMQHAYDFYKPDMLSEYPIVDGKLSIQCYLSALDRCYSVYCKKIHAQWQKEGNDKDFT 254 Query: 834 ISDADYCVFHSPYNKLVQKSFARLYFNDFMRNCSSVDNDAKEKLQPFANLTSEESYQSRD 1013 ++D + +FHSPY KLVQKS AR+ NDF+ + + N L+ F ++ E++Y RD Sbjct: 255 LNDFGFMIFHSPYCKLVQKSLARMLLNDFLNDQNRDKNSIYSGLEAFGDVKLEDTYFDRD 314 Query: 1014 LEKGSQQLAKHLYDIKVQPSTLLPKQIGNMYTASLYAALASVIYN-KHASLNGQRIVMFS 1190 +EK + + L+ K + S L+ Q GNMYT+S+Y +LASV+ L G+RI +FS Sbjct: 315 VEKAFMKASSELFSQKTKASLLVSNQNGNMYTSSVYGSLASVLAQYSPQQLAGKRIGVFS 374 Query: 1191 YGSGLTSTMFSFKLNEGQHPFSLTN--IASVLDVAAKLESRHVTSPEKFIDTLKLMEHRY 1364 YGSGL +T++S K+ + P S + AS+ D+ ++L+SR +P+ F + +KL E + Sbjct: 375 YGSGLAATLYSLKVTQDATPGSALDKITASLCDLKSRLDSRTGVAPDVFAENMKLREDTH 434 Query: 1365 GAKDFETSKDISLLPPGTFYLTKVDSMYRRFYEKK 1469 ++ I L GT+YL +VD +RR Y ++ Sbjct: 435 HLVNYIPQGSIDSLFEGTWYLVRVDEKHRRTYARR 469
>Q8JZK9:HMCS1_MOUSE Hydroxymethylglutaryl-CoA synthase, cytoplasmic - Mus musculus| (Mouse) Length = 520 Score = 441 bits (1135), Expect = e-123 Identities = 224/455 (49%), Positives = 309/455 (67%), Gaps = 8/455 (1%) Frame = +3 Query: 129 KDVGILAMDMYFPPTCVQQEALEVHDGASKGKYTIGLGQDCMAFCSEVEDVISMSLTVVK 308 KDVGI+A+++YFP V Q LE +DG GKYTIGLGQ M FC++ ED+ S+ LTVV+ Sbjct: 15 KDVGIVALEIYFPSQYVDQAELEKYDGVDAGKYTIGLGQARMGFCTDREDINSLCLTVVQ 74 Query: 309 SLLEKYHIDPKLIGRLEVGSETVIDKSKSIKTWLMQIFEESGNTDIEGVDSSNACYGGTA 488 L+E++ + IGRLEVG+ET+IDKSKS+K+ LMQ+FEESGNTDIEG+D++NACYGGTA Sbjct: 75 KLMERHSLSYDCIGRLEVGTETIIDKSKSVKSNLMQLFEESGNTDIEGIDTTNACYGGTA 134 Query: 489 ALLNCVNWVESRCWDGRYGLVVCTDSAVYAEGPARPTGGAAAIAMLIGPNAPISFESKYR 668 A+ N VNWVES WDGRY LVV D A+YA G ARPTGG A+A+LIGPNAP+ F+ R Sbjct: 135 AVFNAVNWVESSSWDGRYALVVAGDIAIYATGNARPTGGVGAVALLIGPNAPLIFDRGLR 194 Query: 669 ASHMAHVYDFYKPDLASEYPVVDGKLSQTCYLMALDSCYRQYCAK-----YEKLVGEQFS 833 +HM H YDFYKPD+ SEYPVVDGKLS CYL ALD CY Y K ++ + F+ Sbjct: 195 GTHMQHAYDFYKPDMLSEYPVVDGKLSIQCYLSALDRCYSVYRKKIRAQWQKEGKDKDFT 254 Query: 834 ISDADYCVFHSPYNKLVQKSFARLYFNDFMRNCSSVDNDAKEKLQPFANLTSEESYQSRD 1013 ++D + +FHSPY KLVQKS AR++ NDF+ + + N L+ F ++ E++Y RD Sbjct: 255 LNDFGFMIFHSPYCKLVQKSLARMFLNDFLNDQNRDKNSIYSGLEAFGDVKLEDTYFDRD 314 Query: 1014 LEKGSQQLAKHLYDIKVQPSTLLPKQIGNMYTASLYAALASVIYN-KHASLNGQRIVMFS 1190 +EK + + L++ K + S L+ Q GNMYT+S+Y +LASV+ L G+R+ +FS Sbjct: 315 VEKAFMKASSELFNQKTKASLLVSNQNGNMYTSSVYGSLASVLAQYSPQQLAGKRVGVFS 374 Query: 1191 YGSGLTSTMFSFKLNEGQHPFSLTN--IASVLDVAAKLESRHVTSPEKFIDTLKLMEHRY 1364 YGSGL +T++S K+ + P S + AS+ D+ ++L+SR +P+ F + +KL E + Sbjct: 375 YGSGLAATLYSLKVTQDATPGSALDKITASLCDLKSRLDSRTCVAPDVFAENMKLREDTH 434 Query: 1365 GAKDFETSKDISLLPPGTFYLTKVDSMYRRFYEKK 1469 ++ I L GT+YL +VD +RR Y ++ Sbjct: 435 HLANYIPQCSIDSLFEGTWYLVRVDEKHRRTYARR 469
>P17425:HMCS1_RAT Hydroxymethylglutaryl-CoA synthase, cytoplasmic - Rattus norvegicus| (Rat) Length = 520 Score = 440 bits (1132), Expect = e-123 Identities = 224/455 (49%), Positives = 308/455 (67%), Gaps = 8/455 (1%) Frame = +3 Query: 129 KDVGILAMDMYFPPTCVQQEALEVHDGASKGKYTIGLGQDCMAFCSEVEDVISMSLTVVK 308 KDVGI+A+++YFP V Q LE +DG GKYTIGLGQ M FC++ ED+ S+ LTVV+ Sbjct: 15 KDVGIVALEIYFPSQYVDQAELEKYDGVDAGKYTIGLGQARMGFCTDREDINSLCLTVVQ 74 Query: 309 SLLEKYHIDPKLIGRLEVGSETVIDKSKSIKTWLMQIFEESGNTDIEGVDSSNACYGGTA 488 L+E+ + IGRLEVG+ET+IDKSKS+K+ LMQ+FEESGNTDIEG+D++NACYGGTA Sbjct: 75 KLMERNSLSYDCIGRLEVGTETIIDKSKSVKSNLMQLFEESGNTDIEGIDTTNACYGGTA 134 Query: 489 ALLNCVNWVESRCWDGRYGLVVCTDSAVYAEGPARPTGGAAAIAMLIGPNAPISFESKYR 668 A+ N VNW+ES WDGRY LVV D A+YA G ARPTGG A+A+LIGPNAP+ F+ R Sbjct: 135 AVFNAVNWIESSSWDGRYALVVAGDIAIYASGNARPTGGVGAVALLIGPNAPVIFDRGLR 194 Query: 669 ASHMAHVYDFYKPDLASEYPVVDGKLSQTCYLMALDSCYRQYCAK-----YEKLVGEQFS 833 +HM H YDFYKPD+ SEYPVVDGKLS CYL ALD CY Y K ++ + F+ Sbjct: 195 GTHMQHAYDFYKPDMLSEYPVVDGKLSIQCYLSALDRCYSVYRKKIRAQWQKEGKDKDFT 254 Query: 834 ISDADYCVFHSPYNKLVQKSFARLYFNDFMRNCSSVDNDAKEKLQPFANLTSEESYQSRD 1013 ++D + +FHSPY KLVQKS AR++ NDF+ + + N L+ F ++ E++Y RD Sbjct: 255 LNDFGFMIFHSPYCKLVQKSLARMFLNDFLNDQNRDKNSIYSGLEAFGDVKLEDTYFDRD 314 Query: 1014 LEKGSQQLAKHLYDIKVQPSTLLPKQIGNMYTASLYAALASVIYN-KHASLNGQRIVMFS 1190 +EK + + L++ K + S L+ Q GNMYT+S+Y +LASV+ L G+RI +FS Sbjct: 315 VEKAFMKASAELFNQKTKASLLVSNQNGNMYTSSVYGSLASVLAQYSPQQLAGKRIGVFS 374 Query: 1191 YGSGLTSTMFSFKLNEGQHPFSLTN--IASVLDVAAKLESRHVTSPEKFIDTLKLMEHRY 1364 YGSGL +T++S K+ + P S + AS+ D+ ++L+SR +P+ F + +KL E + Sbjct: 375 YGSGLAATLYSLKVTQDATPGSALDKITASLCDLKSRLDSRTCVAPDVFAENMKLREDTH 434 Query: 1365 GAKDFETSKDISLLPPGTFYLTKVDSMYRRFYEKK 1469 ++ I L GT+YL +VD +RR Y ++ Sbjct: 435 HLANYIPQCSIDSLFEGTWYLVRVDEKHRRTYARR 469
>P13704:HMCS1_CRIGR Hydroxymethylglutaryl-CoA synthase, cytoplasmic - Cricetulus griseus| (Chinese hamster) Length = 520 Score = 437 bits (1123), Expect = e-122 Identities = 223/455 (49%), Positives = 310/455 (68%), Gaps = 8/455 (1%) Frame = +3 Query: 129 KDVGILAMDMYFPPTCVQQEALEVHDGASKGKYTIGLGQDCMAFCSEVEDVISMSLTVVK 308 KDVGI+A+++YFP V Q LE +DG GKYTIGLGQ M FC++ ED+ S+ LTVV+ Sbjct: 15 KDVGIVALEIYFPSQYVDQAELEKYDGVDAGKYTIGLGQARMGFCTDREDINSLCLTVVQ 74 Query: 309 SLLEKYHIDPKLIGRLEVGSETVIDKSKSIKTWLMQIFEESGNTDIEGVDSSNACYGGTA 488 +L+E+ + IGRLEVG+ET+IDKSKS+K+ LMQ+FEESGNTDIEG+D++NACYGGTA Sbjct: 75 NLMERNSLSYDCIGRLEVGTETIIDKSKSVKSNLMQLFEESGNTDIEGIDTTNACYGGTA 134 Query: 489 ALLNCVNWVESRCWDGRYGLVVCTDSAVYAEGPARPTGGAAAIAMLIGPNAPISFESKYR 668 A+ N VNW+ES WDGRY LVV D A+YA G ARPTGG A+A+LIGPNAP+ F+ R Sbjct: 135 AVFNAVNWIESSSWDGRYALVVAGDIAIYATGNARPTGGVGAVALLIGPNAPLIFDRGLR 194 Query: 669 ASHMAHVYDFYKPDLASEYPVVDGKLSQTCYLMALDSCYRQY----CAKYEKLVGE-QFS 833 +HM H YDFYKPD+ SEYP+VDGKLS CYL ALD CY Y A+++K + F+ Sbjct: 195 GTHMQHAYDFYKPDMLSEYPIVDGKLSIQCYLSALDRCYSVYRKKIRAQWQKEGNDNDFT 254 Query: 834 ISDADYCVFHSPYNKLVQKSFARLYFNDFMRNCSSVDNDAKEKLQPFANLTSEESYQSRD 1013 ++D + + HSPY KLVQKS AR++ NDF+ + + N L+ F ++ E++Y RD Sbjct: 255 LNDFGFMISHSPYCKLVQKSLARMFLNDFLNDQNRDKNSIYSGLEAFGDVKLEDTYFDRD 314 Query: 1014 LEKGSQQLAKHLYDIKVQPSTLLPKQIGNMYTASLYAALASVIYN-KHASLNGQRIVMFS 1190 +EK + + L++ K + S L+ Q GNMYT+S+Y +LASV+ L G+RI +FS Sbjct: 315 VEKAFMKASSELFNQKTKASLLVSNQNGNMYTSSVYGSLASVLAQYSPQQLAGKRIGVFS 374 Query: 1191 YGSGLTSTMFSFKLNEGQHPFSLTN--IASVLDVAAKLESRHVTSPEKFIDTLKLMEHRY 1364 YGSGL +T++S K+ + P S + AS+ D+ ++L+SR +P+ F + +KL E + Sbjct: 375 YGSGLAATLYSLKVTQDATPGSALDKVTASLCDLKSRLDSRTCVAPDVFAENMKLREDTH 434 Query: 1365 GAKDFETSKDISLLPPGTFYLTKVDSMYRRFYEKK 1469 ++ I L GT+YL +VD +RR Y ++ Sbjct: 435 HLANYIPQCSIDSLFEGTWYLVRVDEKHRRTYARR 469
>P54868:HMCS2_HUMAN Hydroxymethylglutaryl-CoA synthase, mitochondrial precursor - Homo| sapiens (Human) Length = 508 Score = 436 bits (1122), Expect = e-121 Identities = 223/455 (49%), Positives = 303/455 (66%), Gaps = 8/455 (1%) Frame = +3 Query: 129 KDVGILAMDMYFPPTCVQQEALEVHDGASKGKYTIGLGQDCMAFCSEVEDVISMSLTVVK 308 KDVGILA+++YFP V Q LE ++ GKYT+GLGQ M FCS ED+ S+ LTVV+ Sbjct: 52 KDVGILALEVYFPAQYVDQTDLEKYNNVEAGKYTVGLGQTRMGFCSVQEDINSLCLTVVQ 111 Query: 309 SLLEKYHIDPKLIGRLEVGSETVIDKSKSIKTWLMQIFEESGNTDIEGVDSSNACYGGTA 488 L+E+ + +GRLEVG+ET+IDKSK++KT LM++F++SGNTDIEG+D++NACYGGTA Sbjct: 112 RLMERIQLPWDSVGRLEVGTETIIDKSKAVKTVLMELFQDSGNTDIEGIDTTNACYGGTA 171 Query: 489 ALLNCVNWVESRCWDGRYGLVVCTDSAVYAEGPARPTGGAAAIAMLIGPNAPISFESKYR 668 +L N NW+ES WDGRY +VVC D AVY G ARPTGGA A+AMLIGP AP++ E R Sbjct: 172 SLFNAANWMESSSWDGRYAMVVCGDIAVYPSGNARPTGGAGAVAMLIGPKAPLALERGLR 231 Query: 669 ASHMAHVYDFYKPDLASEYPVVDGKLSQTCYLMALDSCYRQYCAKYE---KLVGEQ--FS 833 +HM +VYDFYKP+LASEYP+VDGKLS CYL ALD CY Y K + K G F+ Sbjct: 232 GTHMENVYDFYKPNLASEYPIVDGKLSIQCYLRALDRCYTSYRKKIQNQWKQAGSDRPFT 291 Query: 834 ISDADYCVFHSPYNKLVQKSFARLYFNDFMRNCSSVDNDAKEKLQPFANLTSEESYQSRD 1013 + D Y +FH+P+ K+VQKS ARL FNDF+ S + L+ F L E++Y ++D Sbjct: 292 LDDLQYMIFHTPFCKMVQKSLARLMFNDFLSASSDTQTSLYKGLEAFGGLKLEDTYTNKD 351 Query: 1014 LEKGSQQLAKHLYDIKVQPSTLLPKQIGNMYTASLYAALASVIYNKHA-SLNGQRIVMFS 1190 L+K + ++ ++D K + S L GNMYT+SLY LAS++ + A L G RI FS Sbjct: 352 LDKALLKASQDMFDKKTKASLYLSTHNGNMYTSSLYGCLASLLSHHSAQELAGSRIGAFS 411 Query: 1191 YGSGLTSTMFSFKLNEGQHPFSLTN--IASVLDVAAKLESRHVTSPEKFIDTLKLMEHRY 1364 YGSGL ++ FSF++++ P S + ++S D+ +L SR SPE+F + + E Y Sbjct: 412 YGSGLAASFFSFRVSQDAAPGSPLDKLVSSTSDLPKRLASRKCVSPEEFTEIMNQREQFY 471 Query: 1365 GAKDFETSKDISLLPPGTFYLTKVDSMYRRFYEKK 1469 +F D + L PGT+YL +VD +RR Y ++ Sbjct: 472 HKVNFSPPGDTNSLFPGTWYLERVDEQHRRKYARR 506
>P54869:HMCS2_MOUSE Hydroxymethylglutaryl-CoA synthase, mitochondrial precursor - Mus| musculus (Mouse) Length = 508 Score = 436 bits (1120), Expect = e-121 Identities = 226/454 (49%), Positives = 304/454 (66%), Gaps = 8/454 (1%) Frame = +3 Query: 129 KDVGILAMDMYFPPTCVQQEALEVHDGASKGKYTIGLGQDCMAFCSEVEDVISMSLTVVK 308 KDVGILA+++YFP V Q LE + GKYT+GLGQ M FCS ED+ S+ LTVV+ Sbjct: 52 KDVGILALEVYFPAQYVDQTDLEKFNNVEAGKYTVGLGQTRMGFCSVQEDINSLCLTVVQ 111 Query: 309 SLLEKYHIDPKLIGRLEVGSETVIDKSKSIKTWLMQIFEESGNTDIEGVDSSNACYGGTA 488 L+E+ + +GRLEVG+ET+IDKSK++KT LM++F++SGNTDIEG+D++NACYGGTA Sbjct: 112 RLMERTKLPWDAVGRLEVGTETIIDKSKAVKTVLMELFQDSGNTDIEGIDTTNACYGGTA 171 Query: 489 ALLNCVNWVESRCWDGRYGLVVCTDSAVYAEGPARPTGGAAAIAMLIGPNAPISFESKYR 668 +L N NW+ES WDGRY LVVC D AVY G ARPTGGA A+AMLIGP AP+ E R Sbjct: 172 SLFNAANWMESSYWDGRYALVVCGDIAVYPSGNARPTGGAGAVAMLIGPKAPLVLEQGLR 231 Query: 669 ASHMAHVYDFYKPDLASEYPVVDGKLSQTCYLMALDSCYRQYCAKYE---KLVG--EQFS 833 +HM + YDFYKP+LASEYP+VDGKLS CYL ALD CY Y K + K G + F+ Sbjct: 232 GTHMENAYDFYKPNLASEYPLVDGKLSIQCYLRALDRCYAAYRKKIQNQWKQAGNNQPFT 291 Query: 834 ISDADYCVFHSPYNKLVQKSFARLYFNDFMRNCSSVDNDAKEKLQPFANLTSEESYQSRD 1013 + D Y +FH+P+ K+VQKS ARL FNDF+ + S N+ + L+ F L EE+Y ++D Sbjct: 292 LDDVQYMIFHTPFCKMVQKSLARLMFNDFLSSSSDKQNNLYKGLEAFRGLKLEETYTNKD 351 Query: 1014 LEKGSQQLAKHLYDIKVQPSTLLPKQIGNMYTASLYAALASVIYNKHA-SLNGQRIVMFS 1190 ++K + + +++ K + S L GNMYT+SLY LAS++ + A L G RI FS Sbjct: 352 VDKALLKASLDMFNQKTKASLYLSTNNGNMYTSSLYGCLASLLSHHSAQELAGSRIGAFS 411 Query: 1191 YGSGLTSTMFSFKLNEGQHPFSLTN--IASVLDVAAKLESRHVTSPEKFIDTLKLMEHRY 1364 YGSGL ++ FSF++++ P S ++SV D+ +L+SR SPE+F + + E Y Sbjct: 412 YGSGLAASFFSFRVSKDASPGSPLEKLVSSVSDLPKRLDSRRRMSPEEFTEIMNQREQFY 471 Query: 1365 GAKDFETSKDISLLPPGTFYLTKVDSMYRRFYEK 1466 +F D S L PGT+YL +VD M+RR Y + Sbjct: 472 HKVNFSPPGDTSNLFPGTWYLERVDEMHRRKYAR 505
>P22791:HMCS2_RAT Hydroxymethylglutaryl-CoA synthase, mitochondrial precursor - Rattus| norvegicus (Rat) Length = 508 Score = 434 bits (1117), Expect = e-121 Identities = 225/455 (49%), Positives = 304/455 (66%), Gaps = 8/455 (1%) Frame = +3 Query: 129 KDVGILAMDMYFPPTCVQQEALEVHDGASKGKYTIGLGQDCMAFCSEVEDVISMSLTVVK 308 KDVGILA+++YFP V Q LE + GKYT+GLGQ M FCS ED+ S+ LTVV+ Sbjct: 52 KDVGILALEVYFPAQYVDQTDLEKFNNVEAGKYTVGLGQTRMGFCSVQEDINSLCLTVVQ 111 Query: 309 SLLEKYHIDPKLIGRLEVGSETVIDKSKSIKTWLMQIFEESGNTDIEGVDSSNACYGGTA 488 L+E+ + +GRLEVG+ET+IDKSK++KT LM++F++SGNTDIEG+D++NACYGGTA Sbjct: 112 RLMERTKLPWDAVGRLEVGTETIIDKSKAVKTVLMELFQDSGNTDIEGIDTTNACYGGTA 171 Query: 489 ALLNCVNWVESRCWDGRYGLVVCTDSAVYAEGPARPTGGAAAIAMLIGPNAPISFESKYR 668 +L N NW+ES WDGRY LVVC D AVY G RPTGGA A+AMLIGP AP+ E R Sbjct: 172 SLFNAANWMESSYWDGRYALVVCGDIAVYPSGNPRPTGGAGAVAMLIGPKAPLVLEQGLR 231 Query: 669 ASHMAHVYDFYKPDLASEYPVVDGKLSQTCYLMALDSCYRQYCAKYE---KLVG--EQFS 833 +HM + YDFYKP+LASEYP+VDGKLS CYL ALD CY Y K + K G + F+ Sbjct: 232 GTHMENAYDFYKPNLASEYPLVDGKLSIQCYLRALDRCYAAYRRKIQNQWKQAGNNQPFT 291 Query: 834 ISDADYCVFHSPYNKLVQKSFARLYFNDFMRNCSSVDNDAKEKLQPFANLTSEESYQSRD 1013 + D Y +FH+P+ K+VQKS ARL FNDF+ + S N+ + L+ F L EE+Y ++D Sbjct: 292 LDDVQYMIFHTPFCKMVQKSLARLMFNDFLSSSSDKQNNLYKGLEAFKGLKLEETYTNKD 351 Query: 1014 LEKGSQQLAKHLYDIKVQPSTLLPKQIGNMYTASLYAALASVIYNKHA-SLNGQRIVMFS 1190 ++K + + +++ K + S L GNMYT+SLY LAS++ + A L G RI FS Sbjct: 352 VDKALLKASLDMFNKKTKASLYLSTNNGNMYTSSLYGCLASLLSHHSAQELAGSRIGAFS 411 Query: 1191 YGSGLTSTMFSFKLNEGQHPFSLTN--IASVLDVAAKLESRHVTSPEKFIDTLKLMEHRY 1364 YGSGL ++ FSF++++ P S ++SV D+ +L+SR SPE+F + + E Y Sbjct: 412 YGSGLAASFFSFRVSKDASPGSPLEKLVSSVSDLPKRLDSRRRMSPEEFTEIMNQREQFY 471 Query: 1365 GAKDFETSKDISLLPPGTFYLTKVDSMYRRFYEKK 1469 +F D S L PGT+YL +VD M+RR Y ++ Sbjct: 472 HKVNFSPPGDTSNLFPGTWYLERVDEMHRRKYARR 506
>P23228:HMCS1_CHICK Hydroxymethylglutaryl-CoA synthase, cytoplasmic - Gallus gallus| (Chicken) Length = 522 Score = 433 bits (1114), Expect = e-120 Identities = 230/479 (48%), Positives = 318/479 (66%), Gaps = 13/479 (2%) Frame = +3 Query: 129 KDVGILAMDMYFPPTCVQQEALEVHDGASKGKYTIGLGQDCMAFCSEVEDVISMSLTVVK 308 KDVGI+A+++YFP V Q LE +DG GKYTIGLGQ M FCS+ ED+ S+ LTVV+ Sbjct: 15 KDVGIVALEIYFPSQYVDQTELEKYDGVDAGKYTIGLGQSKMGFCSDREDINSLCLTVVQ 74 Query: 309 SLLEKYHIDPKLIGRLEVGSETVIDKSKSIKTWLMQIFEESGNTDIEGVDSSNACYGGTA 488 L+E+ + IGRLEVG+ET+IDKSKS+KT LMQ+FEESGNTD+EG+D++NACYGGTA Sbjct: 75 KLMERNSLSYDCIGRLEVGTETIIDKSKSVKTVLMQLFEESGNTDVEGIDTTNACYGGTA 134 Query: 489 ALLNCVNWVESRCWDGRYGLVVCTDSAVYAEGPARPTGGAAAIAMLIGPNAPISFESKYR 668 AL N +NW+ES WDGRY LVV D AVYA G ARPTGGA A+AML+G NAP+ FE R Sbjct: 135 ALFNAINWIESSSWDGRYALVVAGDIAVYATGNARPTGGAGAVAMLVGSNAPLIFERGLR 194 Query: 669 ASHMAHVYDFYKPDLASEYPVVDGKLSQTCYLMALDSCYRQY----CAKYEKLVGEQ-FS 833 +HM H YDFYKPD+ SEYPVVDGKLS CYL ALD CY Y A+++K ++ F+ Sbjct: 195 GTHMQHAYDFYKPDMVSEYPVVDGKLSIQCYLSALDRCYSVYRNKIHAQWQKEGTDRGFT 254 Query: 834 ISDADYCVFHSPYNKLVQKSFARLYFNDFMRNCSS-VDNDAKEKLQPFANLTSEESYQSR 1010 ++D + +FHSPY KLVQKS ARL NDF+ + ++ N L+ F ++ E++Y R Sbjct: 255 LNDFGFMIFHSPYCKLVQKSVARLLLNDFLSDQNAETANGVFSGLEAFRDVKLEDTYFDR 314 Query: 1011 DLEKGSQQLAKHLYDIKVQPSTLLPKQIGNMYTASLYAALASVIYN-KHASLNGQRIVMF 1187 D+EK + + L++ K + S L+ Q GNMYT S+Y LAS++ L GQRI F Sbjct: 315 DVEKAFMKASAELFNQKTKASLLVSNQNGNMYTPSVYGCLASLLAQYSPEHLAGQRISEF 374 Query: 1188 SYGSGLTSTMFSFKLNEGQHPFSLTN--IASVLDVAAKLESRHVTSPEKFIDTLKLMEHR 1361 SYGSG +T++S ++ + P S + AS+ D+ A+L+SR +P+ F + +K+ + Sbjct: 375 SYGSGFAATLYSIRVTQDATPGSALDKITASLSDLKARLDSRKCIAPDVFAENMKIRQET 434 Query: 1362 YGAKDFETSKDISLLPPGTFYLTKVDSMYRRFYEKKT---DGIVDGKIKCSN-GIANGH 1526 + ++ + L GT+YL +VD +RR Y ++ DG ++ ++ + GI + H Sbjct: 435 HHLANYIPQCSVEDLFEGTWYLVRVDEKHRRTYARRPVMGDGPLEAGVEVVHPGIVHEH 493
>Q2KIE6:HMCS2_BOVIN Hydroxymethylglutaryl-CoA synthase, mitochondrial precursor - Bos| taurus (Bovine) Length = 508 Score = 432 bits (1110), Expect = e-120 Identities = 222/455 (48%), Positives = 299/455 (65%), Gaps = 8/455 (1%) Frame = +3 Query: 129 KDVGILAMDMYFPPTCVQQEALEVHDGASKGKYTIGLGQDCMAFCSEVEDVISMSLTVVK 308 KDVGILAM++YFP V Q LE + G+YT+GLGQ M FCS EDV S+ LTVV+ Sbjct: 52 KDVGILAMEVYFPAQYVDQTELEKFNKVEAGRYTVGLGQTQMGFCSVQEDVNSLCLTVVQ 111 Query: 309 SLLEKYHIDPKLIGRLEVGSETVIDKSKSIKTWLMQIFEESGNTDIEGVDSSNACYGGTA 488 L+E+ + +GRLEVG+ET+IDKSK++KT LM++F++SGNTDIEG+D++NACYGGTA Sbjct: 112 QLMERTQLPWDSVGRLEVGTETIIDKSKAVKTVLMELFQDSGNTDIEGIDTTNACYGGTA 171 Query: 489 ALLNCVNWVESRCWDGRYGLVVCTDSAVYAEGPARPTGGAAAIAMLIGPNAPISFESKYR 668 +L N NW+ES WDGRY LVVC D AVY G ARPTGGA A+AML+GP AP+ E R Sbjct: 172 SLFNAANWMESSSWDGRYALVVCGDIAVYPSGNARPTGGAGAVAMLVGPEAPLVLERGLR 231 Query: 669 ASHMAHVYDFYKPDLASEYPVVDGKLSQTCYLMALDSCYRQYCAKYEKL-----VGEQFS 833 +HM +VYDFYKPD+ SEYP+VDGKLS CYL ALD CY Y K EK + F+ Sbjct: 232 GTHMENVYDFYKPDVTSEYPLVDGKLSIQCYLRALDKCYAFYRQKIEKQWKQAGIDRPFT 291 Query: 834 ISDADYCVFHSPYNKLVQKSFARLYFNDFMRNCSSVDNDAKEKLQPFANLTSEESYQSRD 1013 + D Y +FH+P+ KLVQKS ARL FNDF+ + L+ F L E++Y ++D Sbjct: 292 LDDVQYMIFHTPFCKLVQKSLARLMFNDFLLASGDTQTGIYKGLEAFRGLKLEDTYTNKD 351 Query: 1014 LEKGSQQLAKHLYDIKVQPSTLLPKQIGNMYTASLYAALASVIYNKHA-SLNGQRIVMFS 1190 ++K + + ++++ K + S L GNMYT+SLY LAS++ + A L G RI FS Sbjct: 352 VDKAFLKASLNMFNKKTKNSLYLSTYNGNMYTSSLYGCLASLLAHHSAQDLAGSRIGAFS 411 Query: 1191 YGSGLTSTMFSFKLNEGQHPFSLTN--IASVLDVAAKLESRHVTSPEKFIDTLKLMEHRY 1364 YGSGL ++ FSF++++ P S ++S D+ +L SR SPE+F + + E Y Sbjct: 412 YGSGLAASFFSFRVSQDASPGSPLEKLVSSTSDLQKRLASRKRVSPEEFTEIMNQREQYY 471 Query: 1365 GAKDFETSKDISLLPPGTFYLTKVDSMYRRFYEKK 1469 +F D + L PGT+YL +VD +YRR Y ++ Sbjct: 472 HKMNFSPPGDKNSLFPGTWYLERVDELYRRKYARR 506
>O02734:HMCS2_PIG Hydroxymethylglutaryl-CoA synthase, mitochondrial precursor - Sus| scrofa (Pig) Length = 508 Score = 425 bits (1092), Expect = e-118 Identities = 219/454 (48%), Positives = 297/454 (65%), Gaps = 8/454 (1%) Frame = +3 Query: 129 KDVGILAMDMYFPPTCVQQEALEVHDGASKGKYTIGLGQDCMAFCSEVEDVISMSLTVVK 308 KDVGILA+++YFP V Q LE D G+YT+GLGQ M FCS ED+ S+ LTVV+ Sbjct: 52 KDVGILALEVYFPAQYVDQTDLEKFDNVEAGRYTVGLGQTHMGFCSVQEDINSLCLTVVQ 111 Query: 309 SLLEKYHIDPKLIGRLEVGSETVIDKSKSIKTWLMQIFEESGNTDIEGVDSSNACYGGTA 488 L+E+ + +G LEVG+ET+IDKSKS+KT LM++F++SGNTDIEG+D++NACYGGTA Sbjct: 112 RLMERTQLPWDSVGWLEVGTETIIDKSKSVKTVLMELFQDSGNTDIEGIDTTNACYGGTA 171 Query: 489 ALLNCVNWVESRCWDGRYGLVVCTDSAVYAEGPARPTGGAAAIAMLIGPNAPISFESKYR 668 +L N NWVES WDGRY +VVC D AVY G +RPTGGA A+AML+GP AP++ E R Sbjct: 172 SLFNAANWVESSAWDGRYAVVVCGDIAVYPRGNSRPTGGAGAVAMLVGPEAPLALERGLR 231 Query: 669 ASHMAHVYDFYKPDLASEYPVVDGKLSQTCYLMALDSCYRQYCAKYEKL-----VGEQFS 833 +HM + YDFYKP+ SEYP+VDGKLS CYL ALD CY Y K EK + F+ Sbjct: 232 GTHMENAYDFYKPNATSEYPLVDGKLSIQCYLRALDRCYTLYRQKIEKQWKQAGIERHFT 291 Query: 834 ISDADYCVFHSPYNKLVQKSFARLYFNDFMRNCSSVDNDAKEKLQPFANLTSEESYQSRD 1013 + D + +FH+P+ KLVQKS ARL F+DF+ S + + L+ F E++Y ++D Sbjct: 292 LDDLQFMIFHTPFCKLVQKSLARLMFSDFLLADSDTQSSLYKGLEAFRGQKLEDTYANKD 351 Query: 1014 LEKGSQQLAKHLYDIKVQPSTLLPKQIGNMYTASLYAALASVIYNKHA-SLNGQRIVMFS 1190 +EK Q+ + L++ K +PS L GNMYT+SLY LAS++ A L G RI FS Sbjct: 352 IEKAFQKASLDLFNKKTKPSLYLSLHNGNMYTSSLYGCLASLLSQCSAQDLAGSRIGAFS 411 Query: 1191 YGSGLTSTMFSFKLNEGQHPFSLTN--IASVLDVAAKLESRHVTSPEKFIDTLKLMEHRY 1364 YGSGL ++ +S ++++ P S ++SV D+ +L SR SPE+F + + E Y Sbjct: 412 YGSGLAASFYSLRVSQDASPGSPLEKLVSSVSDLPERLASRKRVSPEEFTEIMNQREQYY 471 Query: 1365 GAKDFETSKDISLLPPGTFYLTKVDSMYRRFYEK 1466 +F D + L PGT+YL +VD +YRR Y + Sbjct: 472 HKVNFTPPGDPNSLFPGTWYLERVDELYRRKYAR 505
>P54870:HMCS2_BLAGE Hydroxymethylglutaryl-CoA synthase 2 - Blattella germanica (German| cockroach) Length = 455 Score = 408 bits (1049), Expect = e-113 Identities = 218/455 (47%), Positives = 296/455 (65%), Gaps = 9/455 (1%) Frame = +3 Query: 129 KDVGILAMDMYFPPTCVQQEALEVHDGASKGKYTIGLGQDCMAFCSEVEDVISMSLTVVK 308 +DVGI+ ++M FP V Q LE +D S GKYT+GLGQD M C++ ED+ S+ LT V Sbjct: 6 EDVGIIGIEMIFPSLYVDQAELETYDEVSPGKYTMGLGQDKMGVCTDREDINSLCLTAVD 65 Query: 309 SLLEKYHIDPKLIGRLEVGSETVIDKSKSIKTWLMQIFEESGNTDIEGVDSSNACYGGTA 488 L+E+ +ID IG LEVG+ET++DK KS+KT LMQ+FEESGNTD+EG+D+ NACY GTA Sbjct: 66 KLMERNNIDYNDIGWLEVGTETILDKVKSVKTVLMQLFEESGNTDVEGIDTINACYRGTA 125 Query: 489 ALLNCVNWVESRCWDGRYGLVVCTDSAVYAEGPARPTGGAAAIAMLIGPNAPISFESKYR 668 AL N + W+ES WDGRY +VV D A+YA+ PTGGA A+ MLIG NAPI + R Sbjct: 126 ALFNALIWIESSSWDGRYAIVVAADIAIYAK-ECSPTGGAGALLMLIGANAPIVIDRGVR 184 Query: 669 ASHMAHVYDFYKPDLASEYPVVDGKLSQTCYLMALDSCYRQYCAKYEKLV---GEQFSIS 839 ASHM H YDFYKPDL SEYPVVDGKLS CYL ALD CY ++C+K EK + G++ + Sbjct: 185 ASHMKHAYDFYKPDLMSEYPVVDGKLSVQCYLSALDHCYPRFCSKTEKYLKRCGKENTKI 244 Query: 840 DADY---CVFHSPYNKLVQKSFARLYFNDFMRNCSSVDNDAKEKLQPFANLTSEESYQSR 1010 D DY VFHSPY KLVQKS ARL NDF++ + + LQ NL E++Y R Sbjct: 245 DLDYFDAFVFHSPYCKLVQKSVARLVLNDFIQY-----PEKYQDLQQLRNLKFEDTYFDR 299 Query: 1011 DLEKGSQQLAKHLYDIKVQPSTLLPKQIGNMYTASLYAALASVIYNKH-ASLNGQRIVMF 1187 D+EK +K L++ K +PS +L Q+GNMYT SLY L S++ ++ L G+ I MF Sbjct: 300 DIEKIFMDKSKQLFEKKTKPSLMLANQVGNMYTTSLYGGLVSLLISEDIGELAGKCICMF 359 Query: 1188 SYGSGLTSTMFSFKLNEGQHPFSLTN--IASVLDVAAKLESRHVTSPEKFIDTLKLMEHR 1361 SYGSG ++MFS ++ P S + + ++ + +++ R SP +F + +++ E Sbjct: 360 SYGSGFAASMFSLHISTDSSPGSTLSRLVTNLTHIKPQVQQRVKLSPGEFENIMEIREQN 419 Query: 1362 YGAKDFETSKDISLLPPGTFYLTKVDSMYRRFYEK 1466 + + + L PGT+YL +DSM+RR Y++ Sbjct: 420 HHKAPYTPVASPNTLFPGTWYLESIDSMHRRKYKR 454
>P54839:HMCS_YEAST Hydroxymethylglutaryl-CoA synthase - Saccharomyces cerevisiae| (Baker's yeast) Length = 491 Score = 385 bits (988), Expect = e-106 Identities = 215/457 (47%), Positives = 286/457 (62%), Gaps = 10/457 (2%) Frame = +3 Query: 129 KDVGILAMDMYFPPTCVQQEALEVHDGASKGKYTIGLGQDCMAFCSEVEDVISMSLTVVK 308 ++VGI + +Y P CV Q LE DG S+GKYTIGLGQ M+F ++ ED+ SMSLTV+ Sbjct: 47 QNVGIKGIQIYIPTQCVNQSELEKFDGVSQGKYTIGLGQTNMSFVNDREDIYSMSLTVLS 106 Query: 309 SLLEKYHIDPKLIGRLEVGSETVIDKSKSIKTWLMQIFEESGNTDIEGVDSSNACYGGTA 488 L++ Y+ID IGRLEVG+ET+IDKSKS+K+ LMQ+F E NTD+EG+D+ NACYGGT Sbjct: 107 KLIKSYNIDTNKIGRLEVGTETLIDKSKSVKSVLMQLFGE--NTDVEGIDTLNACYGGTN 164 Query: 489 ALLNCVNWVESRCWDGRYGLVVCTDSAVYAEGPARPTGGAAAIAMLIGPNAPISFESKYR 668 AL N +NW+ES WDGR +VVC D A+Y +G ARPTGGA +AM IGP+API F+S R Sbjct: 165 ALFNSLNWIESNAWDGRDAIVVCGDIAIYDKGAARPTGGAGTVAMWIGPDAPIVFDS-VR 223 Query: 669 ASHMAHVYDFYKPDLASEYPVVDGKLSQTCYLMALDSCYRQYCAK-YEKLVGEQFSISDA 845 AS+M H YDFYKPD SEYP VDG S TCY+ ALD Y+ Y K K + + SDA Sbjct: 224 ASYMEHAYDFYKPDFTSEYPYVDGHFSLTCYVKALDQVYKSYSKKAISKGLVSDPAGSDA 283 Query: 846 -------DYCVFHSPYNKLVQKSFARLYFNDFMRNCSSVDNDAKEKLQPFANLTSEESYQ 1004 DY VFH P KLV KS+ RL +NDF N E A +ES Sbjct: 284 LNVLKYFDYNVFHVPTCKLVTKSYGRLLYNDFRANPQLFPEVDAE----LATRDYDESLT 339 Query: 1005 SRDLEKGSQQLAKHLYDIKVQPSTLLPKQIGNMYTASLYAALASVI-YNKHASLNGQRIV 1181 +++EK +AK + +V S ++P GNMYTAS+YAA AS++ Y L G+R+ Sbjct: 340 DKNIEKTFVNVAKPFHKERVAQSLIVPTNTGNMYTASVYAAFASLLNYVGSDDLQGKRVG 399 Query: 1182 MFSYGSGLTSTMFSFKL-NEGQHPFSLTNIASVLDVAAKLESRHVTSPEKFIDTLKLMEH 1358 +FSYGSGL ++++S K+ + QH I LD+ KL R +P+ + ++L E+ Sbjct: 400 LFSYGSGLAASLYSCKIVGDVQH------IIKELDITNKLAKRITETPKDYEAAIELREN 453 Query: 1359 RYGAKDFETSKDISLLPPGTFYLTKVDSMYRRFYEKK 1469 + K+F+ I L G +YLT +D +RR Y+ K Sbjct: 454 AHLKKNFKPQGSIEHLQSGVYYLTNIDDKFRRSYDVK 490
>P54874:HMCS_SCHPO Hydroxymethylglutaryl-CoA synthase - Schizosaccharomyces pombe| (Fission yeast) Length = 447 Score = 379 bits (972), Expect = e-104 Identities = 201/454 (44%), Positives = 280/454 (61%), Gaps = 5/454 (1%) Frame = +3 Query: 123 DCKDVGILAMDMYFPPTCVQQEALEVHDGASKGKYTIGLGQDCMAFCSEVEDVISMSLTV 302 D KD+GI + +Y P V+Q ALE HDG S GKYTIGLG MAF + ED+ S LT Sbjct: 4 DRKDIGIKGLVLYTPNQYVEQAALEAHDGVSTGKYTIGLGLTKMAFVDDREDIYSFGLTA 63 Query: 303 VKSLLEKYHIDPKLIGRLEVGSETVIDKSKSIKTWLMQIFEESGNTDIEGVDSSNACYGG 482 + L+++Y ID IGRLEVG+ET+IDKSKS+K+ LMQ+F ++ N +EG+D NACYGG Sbjct: 64 LSQLIKRYQIDISKIGRLEVGTETIIDKSKSVKSVLMQLFGDNHN--VEGIDCVNACYGG 121 Query: 483 TAALLNCVNWVESRCWDGRYGLVVCTDSAVYAEGPARPTGGAAAIAMLIGPNAPISFESK 662 AL N ++W+ES WDGR G+VV D A+YA+G ARPTGGA +A+L+GPNAPI FE Sbjct: 122 VNALFNTIDWIESSAWDGRDGIVVAGDIALYAKGNARPTGGAGCVALLVGPNAPIVFEPG 181 Query: 663 YRASHMAHVYDFYKPDLASEYPVVDGKLSQTCYLMALDSCYRQY----CAKYEKLVGEQF 830 R ++M H YDFYKPDL SEYP VDG S CY+ ALD Y Y AK K G Sbjct: 182 LRGTYMQHAYDFYKPDLTSEYPYVDGHFSLECYVKALDGAYANYNVRDVAKNGKSQG--L 239 Query: 831 SISDADYCVFHSPYNKLVQKSFARLYFNDFMRNCSSVDNDAKEKLQPFANLTSEESYQSR 1010 + DYC+FH+P K VQK++ARL + D S+ + + +L + L +++S + Sbjct: 240 GLDRFDYCIFHAPTCKQVQKAYARLLYTDSAAEPSNPELEGVREL--LSTLDAKKSLTDK 297 Query: 1011 DLEKGSQQLAKHLYDIKVQPSTLLPKQIGNMYTASLYAALASVIYNKHA-SLNGQRIVMF 1187 LEKG + K ++ +V PS P GNMYTAS+++ L +++ A L G+R+ + Sbjct: 298 ALEKGLMAITKERFNKRVSPSVYAPTNCGNMYTASIFSCLTALLSRVPADELKGKRVGAY 357 Query: 1188 SYGSGLTSTMFSFKLNEGQHPFSLTNIASVLDVAAKLESRHVTSPEKFIDTLKLMEHRYG 1367 SYGSGL ++ FSF + ++ IA ++ L++RH +P ++ + ++L + Sbjct: 358 SYGSGLAASFFSFVVKG-----DVSEIAKKTNLVNDLDNRHCLTPTQYEEAIELRHQAHL 412 Query: 1368 AKDFETSKDISLLPPGTFYLTKVDSMYRRFYEKK 1469 K+F I L GT+YLT +D M+RR Y K Sbjct: 413 KKNFTPKGSIERLRSGTYYLTGIDDMFRRSYSVK 446
>P54871:HMCS_CAEEL Hydroxymethylglutaryl-CoA synthase - Caenorhabditis elegans| Length = 462 Score = 296 bits (757), Expect = 3e-79 Identities = 180/472 (38%), Positives = 266/472 (56%), Gaps = 4/472 (0%) Frame = +3 Query: 132 DVGILAMDMYFPPTCVQQEALEVHDGASKGKYTIGLGQDCMAFCSEVEDVISMSLTVVKS 311 DVGI A+++YFP V Q LE + S GKYTIGLGQ M FCS+ ED++S+SLTV + Sbjct: 13 DVGIGAIELYFPQNFVDQNDLEKFNNVSSGKYTIGLGQQQMGFCSDNEDIVSISLTVTRK 72 Query: 312 LLEKYHIDPKLIGRLEVGSETVIDKSKSIKTWLMQIFEESGNTDIEGVDSSNACYGGTAA 491 L+E Y I IG L VG+ET+IDKSKS+KT LM +F GN+DIEGVD NAC+GG A Sbjct: 73 LIETYKISTDSIGCLVVGTETMIDKSKSVKTALMDLF--PGNSDIEGVDIKNACFGGAQA 130 Query: 492 LLNCVNWVE-SRCWDGRYGLVVCTDSAVYAEGPARPTGGAAAIAMLIGPNAPISFESKYR 668 LL+ ++WV + D + +VV D A+Y EGPAR TGGA AIA LI P+A I + ++ Sbjct: 131 LLHAIDWVTVNHPLDKKNAIVVVADIAIYEEGPARCTGGAGAIAFLICPDASIPIDRQFS 190 Query: 669 ASHMAHVYDFYKP--DLASEYPVVDGKLSQTCYLMALDSCYRQYCAKYEKLVGEQFSISD 842 A HM + +DF+KP + SEYPVVDG LS + YL A+ Y + +K + ++ Sbjct: 191 ACHMKNTWDFFKPITPIPSEYPVVDGSLSLSSYLEAVRMTYTYFISKVNRHTTGIDGLNS 250 Query: 843 ADYCVFHSPYNKLVQKSFARLYFNDF-MRNCSSVDNDAKEKLQPFANLTSEESYQSRDLE 1019 D HSP+ K+VQK A + + D +R+ N KL ++ + ++ +E Sbjct: 251 FDGVFLHSPFTKMVQKGLAVMNYTDSQLRHKQLNGNGVDHKLD-----ENDRAGLAKMIE 305 Query: 1020 KGSQQLAKHLYDIKVQPSTLLPKQIGNMYTASLYAALASVIYNKHASLNGQRIVMFSYGS 1199 L+ ++ K P + ++IGNMYT SL+A L + + + I+ F+YGS Sbjct: 306 -----LSAQVWKEKTDPYLVFNRRIGNMYTPSLFAQLLAYLAADDCVTGEKSILFFAYGS 360 Query: 1200 GLTSTMFSFKLNEGQHPFSLTNIASVLDVAAKLESRHVTSPEKFIDTLKLMEHRYGAKDF 1379 GL S +F ++ + + + +A + +L+ R +PE+F +TL+ E +K+ Sbjct: 361 GLASAIFPGRVRQTSNLDKIRQVA--IRAIKRLDDRIQFTPEEFTETLQKREVFLRSKEI 418 Query: 1380 ETSKDISLLPPGTFYLTKVDSMYRRFYEKKTDGIVDGKIKCSNGIANGH*WH 1535 S + L P T++L +D +YRR Y + NG+ NG+ H Sbjct: 419 PKSPSETSLFPNTYFLDNMDKLYRRSYTLHEE---------PNGVQNGNGIH 461
>P54872:HMCS_DICDI Hydroxymethylglutaryl-CoA synthase - Dictyostelium discoideum (Slime| mold) Length = 163 Score = 95.5 bits (236), Expect = 7e-19 Identities = 52/139 (37%), Positives = 81/139 (58%) Frame = +3 Query: 1050 YDIKVQPSTLLPKQIGNMYTASLYAALASVIYNKHASLNGQRIVMFSYGSGLTSTMFSFK 1229 Y KV P+TLL KQ+GN Y S Y+ L S++ K L G+R++ FSYGSGL ++ FSFK Sbjct: 6 YATKVAPTTLLAKQLGNTYCGSTYSGLLSLLDEKSNDLVGKRVLTFSYGSGLAASAFSFK 65 Query: 1230 LNEGQHPFSLTNIASVLDVAAKLESRHVTSPEKFIDTLKLMEHRYGAKDFETSKDISLLP 1409 + + + +I +D+ +L R PE F + L L E R+ K++ S + + + Sbjct: 66 VEK-----PINHIVEKVDLKNRLAKRVRVEPEIFTEKLSLRETRHNLKNYVPSDETTNMF 120 Query: 1410 PGTFYLTKVDSMYRRFYEK 1466 PG+FYL+ VD R +++ Sbjct: 121 PGSFYLSSVDKAGIRKFDR 139
>Q8TVL0:Y1379_METKA UPF0219 protein MK1379 - Methanopyrus kandleri| Length = 350 Score = 80.9 bits (198), Expect = 2e-14 Identities = 91/371 (24%), Positives = 143/371 (38%), Gaps = 3/371 (0%) Frame = +3 Query: 135 VGILAMDMYFPPTCVQQEALEVHDGASKGKYTIGLGQDCMAFCSEVEDVISMSLTVVKSL 314 VGI+ Y P ++ E + G GL + + SE ED ++++ K+ Sbjct: 7 VGIVGYGAYVPRYRIKAEEIAAVWGDDVDSIKSGLMIEEKSVPSETEDSATIAVEAAKNA 66 Query: 315 LEKYHIDPKLIGRLEVGSETVIDKSKSIKTWLMQIFEESGNTDIEGVDSSNACYGGTAAL 494 + + IDPK IG + VGSE+ K T + D+ D AC GTAA+ Sbjct: 67 VARAEIDPKDIGAIYVGSESPPYAVKPTATIVAAAI--GATPDLTAADYEFACKAGTAAI 124 Query: 495 LNCVNWVESRCWDGRYGLVVCTDSAVYAEG-PARPTGGAAAIAMLIGPNAPISFESKYRA 671 C V S +YGL + D+A A G P T A A +IG ++ E + Sbjct: 125 QTCAGLVASGMI--KYGLAIGADTAQGAPGDPLEYTAAAGGAAFVIGRKKLVA-EMEGTY 181 Query: 672 SHMAHVYDFYKPDLASEYPVVDGKLSQTCYLMALDSCYRQYCAKYEKLVGEQFSIS--DA 845 S+ DF++ + YP G+ + Y ++ + + + E+ +S D Sbjct: 182 SYTTDTPDFWRRE-GQPYPRHGGRFTGA-------PAYFKHIIRAARGLMEELDLSPEDF 233 Query: 846 DYCVFHSPYNKLVQKSFARLYFNDFMRNCSSVDNDAKEKLQPFANLTSEESYQSRDLEKG 1025 DY VFH P K +K L F E+++P Sbjct: 234 DYAVFHQPNGKFPRKVARSLGFE-------------PEQVEP------------------ 262 Query: 1026 SQQLAKHLYDIKVQPSTLLPKQIGNMYTASLYAALASVIYNKHASLNGQRIVMFSYGSGL 1205 T++ ++GN Y+ S + + G RI++ SYGSG Sbjct: 263 ----------------TIVVDRVGNTYSGSSLLGFTAALDRAEP---GDRILVVSYGSGA 303 Query: 1206 TSTMFSFKLNE 1238 S FSF + E Sbjct: 304 GSDAFSFVVTE 314
>Q58941:Y1546_METJA UPF0219 protein MJ1546 - Methanococcus jannaschii| Length = 345 Score = 73.2 bits (178), Expect = 4e-12 Identities = 84/326 (25%), Positives = 127/326 (38%), Gaps = 4/326 (1%) Frame = +3 Query: 273 EDVISMSLTVVKSLLEKYHIDPKLIGRLEVGSETVIDKSKSIKTWLMQIFEESGNTDIEG 452 ED ++++ ++ L++ IDPK IG + VGSE+ K T + + + D+ Sbjct: 48 EDTATIAVEAARNALKRAEIDPKDIGAVYVGSESHPYAVKPTATIVAEAID--ATPDLTA 105 Query: 453 VDSSNACYGGTAALLNCVNWVESRCWDGRYGLVVCTDSAVYAEGPA-RPTGGAAAIAMLI 629 D AC GTA + C+ VES +YGL + D+A A G A T A A +I Sbjct: 106 ADLEFACKAGTAGIQMCMGLVESGLI--KYGLAIGADTAQGAPGDALEYTAAAGGAAYII 163 Query: 630 G-PNAPISFESKYRASHMAHVYDFYKPDLASEYPVVDGKLSQTCYLMALDSCYRQYCAKY 806 G N F Y S+ DF++ + YP G+ + + Y ++ Sbjct: 164 GKSNVIAEFNGTY--SYTTDTPDFWRRE-GKPYPRHGGRFTG-------EPAYFRHVINA 213 Query: 807 EKLVGEQFSI--SDADYCVFHSPYNKLVQKSFARLYFNDFMRNCSSVDNDAKEKLQPFAN 980 K + E+ D DYCVFH P K + L F Sbjct: 214 AKGLMEKMGTKPEDYDYCVFHQPNGKFYIRVAKILGF----------------------- 250 Query: 981 LTSEESYQSRDLEKGSQQLAKHLYDIKVQPSTLLPKQIGNMYTASLYAALASVIYNKHAS 1160 EE Y+ LL IGN Y+ ++ L++V+ N Sbjct: 251 --KEEQYK----------------------IGLLTPYIGNTYSGAVPLGLSNVLDNCE-- 284 Query: 1161 LNGQRIVMFSYGSGLTSTMFSFKLNE 1238 G+RI+ SYGSG S F + + Sbjct: 285 -GGERILAVSYGSGAGSDAFDITVTD 309
>O26883:Y792_METTH UPF0219 protein MTH_792 - Methanobacterium thermoautotrophicum| Length = 346 Score = 72.4 bits (176), Expect = 6e-12 Identities = 94/369 (25%), Positives = 141/369 (38%), Gaps = 2/369 (0%) Frame = +3 Query: 138 GILAMDMYFPPTCVQQEALEVHDGASKGKYTIGLGQDCMAFCSEVEDVISMSLTVVKSLL 317 GI+ +Y P ++ E + G + GL + + ED ++S+ ++ L Sbjct: 3 GIVGYGVYIPSYRIKVEEIARVWGDDPQAISRGLVVEEKSVPGPDEDTATISVEAARNAL 62 Query: 318 EKYHIDPKLIGRLEVGSETVIDKSKSIKTWLMQIFEESGNTDIEGVDSSNACYGGTAALL 497 + IDP IG + VGSE+ K T + + E ++ D AC GTA + Sbjct: 63 RRSQIDPSEIGAVYVGSESHPYAVKPTATIVAEAVE--ATPEMTAADLEFACKAGTAGIQ 120 Query: 498 NCVNWVESRCWDGRYGLVVCTDSAVYAEGPA-RPTGGAAAIAMLIGPNAPISFESKYRAS 674 C+ V+S +YGL V D+A A G A T A A +IG ++ + K S Sbjct: 121 ACMGLVDSGII--KYGLAVGADTAQGAPGDALEYTASAGGAAYVIGGKNCLA-DIKETYS 177 Query: 675 HMAHVYDFYKPDLASEYPVVDGKLS-QTCYLMALDSCYRQYCAKYEKLVGEQFSISDADY 851 DFY+ + YP G+ + + Y + R K S D DY Sbjct: 178 FTTDTPDFYRRE-GMPYPRHGGRFTGEPAYFKHVLGAARGMMEK------TGLSADDFDY 230 Query: 852 CVFHSPYNKLVQKSFARLYFNDFMRNCSSVDNDAKEKLQPFANLTSEESYQSRDLEKGSQ 1031 VFH P K K+ +L F ES Q Sbjct: 231 AVFHQPNGKFYLKAARKLGF---------------------------ESEQ--------- 254 Query: 1032 QLAKHLYDIKVQPSTLLPKQIGNMYTASLYAALASVIYNKHASLNGQRIVMFSYGSGLTS 1211 V+P L P IGN Y+ + LA+ + + G RI+ SYGSG S Sbjct: 255 ----------VKPGLLTP-VIGNTYSGATPVGLAATL---DVAEPGARILAVSYGSGAGS 300 Query: 1212 TMFSFKLNE 1238 F ++N+ Sbjct: 301 DAFIIEVND 309
>P40830:PKSG_BACSU Putative polyketide biosynthesis protein pksG - Bacillus subtilis| Length = 420 Score = 72.4 bits (176), Expect = 6e-12 Identities = 81/330 (24%), Positives = 134/330 (40%), Gaps = 13/330 (3%) Frame = +3 Query: 273 EDVISMSLTVVKSLLEKY-HIDPKLIGRLEVGSETVIDKSKSIKTWLMQIFEESGNTDIE 449 ED ++ + K +++ + I L SE+ ID KS+ T++ + + N + Sbjct: 49 EDPVTFGVNAAKPIIDALSEAEKDRIELLITCSESGIDFGKSLSTYIHEYLGLNRNCRLF 108 Query: 450 GVDSSNACYGGTAALLNCVNWVESRCWDGRYGLVVCTDSA--VYAEGP---------ARP 596 V ACY GTA VN++ S+ G LV+ +D + + AEG A P Sbjct: 109 EV--KQACYSGTAGFQMAVNFILSQTSPGAKALVIASDISRFLIAEGGDALSEDWSYAEP 166 Query: 597 TGGAAAIAMLIGPNAPI-SFESKYRASHMAHVYDFYKPDLASEYPVVDGKLSQTCYLMAL 773 + GA A+A+L+G N + + + V D +P SE D LS YL Sbjct: 167 SAGAGAVAVLVGENPEVFQIDPGANGYYGYEVMDTCRPIPDSE--AGDSDLSLMSYL--- 221 Query: 774 DSCYRQYCAKYEKLVGEQFSISDADYCVFHSPYNKLVQKSFARLYFNDFMRNCSSVDNDA 953 C Q +Y+K V Y +H+P+ +V+ + + S ++ D Sbjct: 222 -DCCEQTFLEYQKRVPGANYQDTFQYLAYHTPFGGMVKGAHRTMMRKVAKVKTSGIETDF 280 Query: 954 KEKLQPFANLTSEESYQSRDLEKGSQQLAKHLYDIKVQPSTLLPKQIGNMYTASLYAALA 1133 +++P N +++GN+ A+L+ ALA Sbjct: 281 LTRVKPGLNYC---------------------------------QRVGNIMGAALFLALA 307 Query: 1134 SVIYNKHASLNGQRIVMFSYGSGLTSTMFS 1223 S I ++ +RI FSYGSG S +S Sbjct: 308 STI-DQGRFDTPKRIGCFSYGSGCCSEFYS 336
>O30256:Y2415_ARCFU UPF0219 protein AF_2415 - Archaeoglobus fulgidus| Length = 343 Score = 69.3 bits (168), Expect = 5e-11 Identities = 88/371 (23%), Positives = 145/371 (39%), Gaps = 3/371 (0%) Frame = +3 Query: 135 VGILAMDMYFPPTCVQQEALEVHDGASKGKYTIGLGQDCMAFCSEVEDVISMSLTVVKSL 314 +GI++ Y P ++ E + G K GLG + ED ++++ + Sbjct: 2 IGIVSYGSYVPKFRIRVEEIARVWGEDAKKIKDGLGVHEKSVPGMDEDAATIAVEAAREA 61 Query: 315 LEKYHIDPKLIGRLEVGSETVIDKSKSIKTWLMQIFEESG-NTDIEGVDSSNACYGGTAA 491 + + I+P+ IG + VGSE+ ++K + E G D D AC GTA Sbjct: 62 IRRAGINPEEIGAVFVGSES---HPYAVKPTATIVGEALGVGNDYFAADLEFACKAGTAG 118 Query: 492 LLNCVNWVESRCWDGRYGLVVCTDSAVYAEGPARPTGGAA-AIAMLIGPNAPISFESKYR 668 + C + V++ +YGL + D++ G A AA A +IG N E+ Y Sbjct: 119 MQICYSMVKAGMI--KYGLAIGADTSQARPGDALEYAAAAGGAAFIIGENPIAEVEATY- 175 Query: 669 ASHMAHVYDFYKPDLASEYPVVDGKLS-QTCYLMALDSCYRQYCAKYEKLVGEQFSISDA 845 S + DF++ DL YP G+ + Y + S + KY + + D Sbjct: 176 -SFTSDTPDFWRRDL-QPYPSHGGRFTGLPAYFRHVISAAKGLMEKY------GYKVEDF 227 Query: 846 DYCVFHSPYNKLVQKSFARLYFNDFMRNCSSVDNDAKEKLQPFANLTSEESYQSRDLEKG 1025 DY VFH P K ++ L F+ +E Sbjct: 228 DYAVFHMPNAKFPVRAAKMLGFS---------------------------------MEHI 254 Query: 1026 SQQLAKHLYDIKVQPSTLLPKQIGNMYTASLYAALASVIYNKHASLNGQRIVMFSYGSGL 1205 SQ L+ K IGN Y+ S LA+ + + +RI++ S+GSG Sbjct: 255 SQ--------------GLVVKAIGNTYSGSSLLGLAATL---DVAEPDERILLVSFGSGA 297 Query: 1206 TSTMFSFKLNE 1238 S F+ ++ + Sbjct: 298 GSDAFAIRVTD 308
>Q51798:Y972_PYRFU UPF0219 protein PF0972 - Pyrococcus furiosus| Length = 350 Score = 64.7 bits (156), Expect = 1e-09 Identities = 97/402 (24%), Positives = 152/402 (37%), Gaps = 11/402 (2%) Frame = +3 Query: 129 KDVGILAMDMYFPPTCVQQEALEVHDGAS----KGKYTIGLGQDCMAFCSEVEDVISMSL 296 KDVGI+ Y P ++ E + G S + K GL ED I++ + Sbjct: 9 KDVGIVGYGAYVPMYRIRNEEIGRVWGVSSFPIEEKAVPGLD----------EDAITIGI 58 Query: 297 TVVKSLLEKYHIDPKLIGRLEVGSETVIDKSKSIKTWLMQIFEESGNT-DIEGVDSSNAC 473 ++ L++ IDP+ I + G+E+ K ++K I E G T D+E D AC Sbjct: 59 EAARNALKRAKIDPQKIRAIWFGTES---KPYAVKPSATIIAEAIGATPDLEAADFEFAC 115 Query: 474 YGGTAALLNCVNWVESRCWDGRYGLVVCTDSAVYAEGP-ARPTGGAAAIAMLIGPNAPIS 650 GT AL + +V S Y + + D+A G T GA A ++G + S Sbjct: 116 KAGTEALQAAIGFVGSGM--AEYAMAIGADTAQGRPGDHLEFTAGAGGAAFIVGEKSNES 173 Query: 651 ---FESKYRASHMAHVYDFYKPDLASEYPVVDGKLSQTCYLMALDSCYRQYCAKYEKLVG 821 FE Y S++ DF++ YP + + + Y + K + Sbjct: 174 VAYFEGSY--SYVTDTPDFWRRQ-HEHYPRHGNRFTG-------EPAYFHHIINAAKTLM 223 Query: 822 EQFSI--SDADYCVFHSPYNKLVQKSFARLYFNDFMRNCSSVDNDAKEKLQPFANLTSEE 995 E+ + SD DY VFH P K F + + KEK+ P Sbjct: 224 EELGLKPSDFDYAVFHQPNVK-------------FPLTVAKILGIPKEKVLP-------- 262 Query: 996 SYQSRDLEKGSQQLAKHLYDIKVQPSTLLPKQIGNMYTASLYAALASVIYNKHASLNGQR 1175 LL +IGN Y+ + +++V+ + G R Sbjct: 263 --------------------------GLLTGRIGNTYSGATMVGVSAVL---DIAKPGDR 293 Query: 1176 IVMFSYGSGLTSTMFSFKLNEGQHPFSLTNIASVLDVAAKLE 1301 I+ S+GSG S FS + + I D+A K+E Sbjct: 294 ILWVSFGSGAGSNAFSIVVQDA--------IEEKRDLAPKVE 327
>Q6LXY3:Y1211_METMP UPF0219 protein MMP1211 - Methanococcus maripaludis| Length = 349 Score = 64.3 bits (155), Expect = 2e-09 Identities = 93/417 (22%), Positives = 161/417 (38%), Gaps = 6/417 (1%) Frame = +3 Query: 129 KDVGILAMDMYFPPTCVQQEALEVHDGASKGKYTIGLGQDCMAFCSEVEDVISMSLTVVK 308 K+VGI+ P ++ E + G GL + + ED ++++ + Sbjct: 2 KEVGIVGYGSDLPKYRIKAEDIAGAWGKDAQAIKRGLVVNEKSVPGPDEDTATIAVQSAR 61 Query: 309 SLLEKYHIDPKLIGRLEVGSETVIDKSKSIKTWLMQIFEESG-NTDIEGVDSSNACYGGT 485 L + I+PK IG + VGSE+ ++K + E G + D D AC GT Sbjct: 62 RALSRAGINPKDIGAVYVGSES---HPYAVKPTSGIVAEACGVSPDFTAADLEFACKAGT 118 Query: 486 AALLNCVNWVESRCWDGRYGLVVCTDSAVYAEGPARP-TGGAAAIAMLIGPNAPISFESK 662 A + C+ V S + Y + V D+A A G A T A A +IG F +K Sbjct: 119 AGIQMCMGLVGSEMME--YAMAVGADTAQGAPGDALEYTAAAGGAAFIIGAKKE-EFIAK 175 Query: 663 YRA--SHMAHVYDFYKPDLASEYPVVDGKLSQTCYLMALDSCYRQYCAKYEKLVGEQFSI 836 + S+ DF++ + YP G+ + + Y ++ K + E+ Sbjct: 176 FNGTYSYTTDTPDFWRRE-HEHYPKHGGRFTG-------EPAYFKHVLNGAKGMMEKMGT 227 Query: 837 S--DADYCVFHSPYNKLVQKSFARLYFNDFMRNCSSVDNDAKEKLQPFANLTSEESYQSR 1010 + D DYCVFH P K + +L F +EE Y+ Sbjct: 228 TSKDYDYCVFHQPNGKFYLTAAKKLGF-------------------------TEEQYK-- 260 Query: 1011 DLEKGSQQLAKHLYDIKVQPSTLLPKQIGNMYTASLYAALASVIYNKHASLNGQRIVMFS 1190 LL +GN Y+ ++ L++++ + A RI + S Sbjct: 261 --------------------YGLLTPYLGNTYSGAVPLGLSNILDHAKAD---DRIFVVS 297 Query: 1191 YGSGLTSTMFSFKLNEGQHPFSLTNIASVLDVAAKLESRHVTSPEKFIDTLKLMEHR 1361 YGSG S F + + I+ V+D ++ + + +K++D +++R Sbjct: 298 YGSGAGSDAFDITVTD--------RISEVVD--KEITTEKLLEQKKYVDYAVYLKYR 344
>Q8ZVP4:Y2185_PYRAE UPF0219 protein PAE2185 - Pyrobaculum aerophilum| Length = 350 Score = 63.2 bits (152), Expect = 4e-09 Identities = 78/325 (24%), Positives = 128/325 (39%), Gaps = 3/325 (0%) Frame = +3 Query: 273 EDVISMSLTVVKSLLEKYHIDPKLIGRLEVGSETVIDKSKSIKTWLMQIFEESGNTDIEG 452 ED +++++ + L++ I+PK IG + VG+E+ K I + L+ S N + Sbjct: 50 EDAVTIAVEAARRALKRAGINPKRIGAVYVGTESKPYAVKPISSILVDALGLSNN--VFA 107 Query: 453 VDSSNACYGGTAALLNCVNWVESRCWDGR--YGLVVCTDSAVYAEGPARPTGGAAAIAML 626 VD AC G+ L+ + VES GR YG+ V TD++ G ++ A L Sbjct: 108 VDMEFACKAGSEGLVAAIGLVES----GRIEYGMTVGTDTSQGEPGEHLEYSASSGGASL 163 Query: 627 IGPNAPISFESKYRASHMAHVYDFYKPDLASEYPV-VDGKLSQTCYLMALDSCYRQYCAK 803 I + E + S+++ DF++ + S YP+ +G + Y + R + Sbjct: 164 IVGRDGVVAELEAVYSYVSDTPDFWRRE-GSPYPMHGEGFTGEPAYFRHIIGAARGLMER 222 Query: 804 YEKLVGEQFSISDADYCVFHSPYNKLVQKSFARLYFNDFMRNCSSVDNDAKEKLQPFANL 983 Y + SD Y VFH P + F +S+ N EK++P + Sbjct: 223 Y------GYKPSDFAYVVFHQPNGR-------------FPVRAASMLNIPMEKVKPGIVV 263 Query: 984 TSEESYQSRDLEKGSQQLAKHLYDIKVQPSTLLPKQIGNMYTASLYAALASVIYNKHASL 1163 T IGN Y AS A V+ + Sbjct: 264 T----------------------------------HIGNTYNASALMGFAKVL---DIAK 286 Query: 1164 NGQRIVMFSYGSGLTSTMFSFKLNE 1238 G +I++ +GSG S F F + E Sbjct: 287 PGDKILLVPFGSGAGSNAFVFTVTE 311
>O58410:Y677_PYRHO UPF0219 protein PH0677 - Pyrococcus horikoshii| Length = 350 Score = 62.4 bits (150), Expect = 6e-09 Identities = 92/381 (24%), Positives = 146/381 (38%), Gaps = 11/381 (2%) Frame = +3 Query: 129 KDVGILAMDMYFPPTCVQQEALEVHDGAS----KGKYTIGLGQDCMAFCSEVEDVISMSL 296 KDVGI+ Y P ++ E + G S + K GL ED I++ + Sbjct: 9 KDVGIVGYGAYVPMYRIRNEEIGRVWGISNFPIEEKAVPGLD----------EDAITIGI 58 Query: 297 TVVKSLLEKYHIDPKLIGRLEVGSETVIDKSKSIKTWLMQIFEESGNT-DIEGVDSSNAC 473 ++ L++ IDPK I + GSE+ K ++K I E G T D+E D AC Sbjct: 59 EAARNALKRAKIDPKDIRAIWFGSES---KPYAVKPSSTVIAEAIGATPDLEAADFEFAC 115 Query: 474 YGGTAALLNCVNWVESRCWDGRYGLVVCTDSAVYAEGP-ARPTGGAAAIAMLIGPNAPIS 650 GT AL + +V S +Y + + D+A G T GA A +IG + + Sbjct: 116 KAGTEALQAAIGFVASGM--AKYAMAIGADTAQGRPGDHLEFTAGAGGAAFIIGEKSSET 173 Query: 651 ---FESKYRASHMAHVYDFYKPDLASEYPVVDGKLSQTCYLMALDSCYRQYCAKYEKLVG 821 FE Y S++ DF++ YP + + + Y + K + Sbjct: 174 VAYFEGSY--SYVTDTPDFWRRQ-HEHYPRHGNRFTG-------EPAYFHHVVTAAKTLM 223 Query: 822 EQFSIS--DADYCVFHSPYNKLVQKSFARLYFNDFMRNCSSVDNDAKEKLQPFANLTSEE 995 ++ ++ D DY VFH P K F + + KEK+ P Sbjct: 224 DELGLTPEDFDYAVFHQPNVK-------------FPLVAARMLGIPKEKVLP-------- 262 Query: 996 SYQSRDLEKGSQQLAKHLYDIKVQPSTLLPKQIGNMYTASLYAALASVIYNKHASLNGQR 1175 LL +IGN Y+ + +++V+ + G R Sbjct: 263 --------------------------GLLSGRIGNTYSGATMVGISAVL---DIAKPGDR 293 Query: 1176 IVMFSYGSGLTSTMFSFKLNE 1238 I+ S+GSG S FS + + Sbjct: 294 ILWVSFGSGAGSDAFSIVVQD 314
>Q9UYY8:Y1369_PYRAB UPF0219 protein PYRAB13690 - Pyrococcus abyssi| Length = 350 Score = 60.5 bits (145), Expect = 2e-08 Identities = 93/407 (22%), Positives = 154/407 (37%), Gaps = 16/407 (3%) Frame = +3 Query: 129 KDVGILAMDMYFPPTCVQQEALEVHDGAS----KGKYTIGLGQDCMAFCSEVEDVISMSL 296 K++GI+ Y P ++ E + G S + K GL ED +++ + Sbjct: 9 KEIGIVGYGAYVPMYRIRNEEIGRVWGVSNFPIEEKAVPGLD----------EDAVTIGI 58 Query: 297 TVVKSLLEKYHIDPKLIGRLEVGSETVIDKSKSIKTWLMQIFEESGNT-DIEGVDSSNAC 473 ++ L++ IDP+ I + GSE+ K ++K I E G T D+E D AC Sbjct: 59 EAARNALKRAKIDPREIRAIWFGSES---KPYAVKPSATIIAEAIGATPDLEAADFEFAC 115 Query: 474 YGGTAALLNCVNWVESRCWDGRYGLVVCTDSAVYAEGPARP------TGGAAAIAMLIGP 635 GT AL + +V S +Y + + D+A RP T GA A ++G Sbjct: 116 KAGTEALQAAIGFVASGM--AKYAMAIGADTA-----QGRPADHLEFTAGAGGAAFIVGE 168 Query: 636 NAPIS---FESKYRASHMAHVYDFYKPDLASEYPVVDGKLSQTCYLMALDSCYRQYCAKY 806 + + FE Y S++ DF++ YP + + + Y + Sbjct: 169 KSSETLAYFEGSY--SYVTDTPDFWRRQ-HEHYPRHGNRFTG-------EPAYFHHVITA 218 Query: 807 EKLVGEQFSI--SDADYCVFHSPYNKLVQKSFARLYFNDFMRNCSSVDNDAKEKLQPFAN 980 K + ++ + +D DY VFH P K F + + KEK+ P Sbjct: 219 AKTLMDELGLTPADFDYAVFHQPNVK-------------FPLTAAKILGIPKEKVLP--- 262 Query: 981 LTSEESYQSRDLEKGSQQLAKHLYDIKVQPSTLLPKQIGNMYTASLYAALASVIYNKHAS 1160 LL +IGN Y+ + +++V+ + Sbjct: 263 -------------------------------GLLTGKIGNTYSGATMVGISAVL---DIA 288 Query: 1161 LNGQRIVMFSYGSGLTSTMFSFKLNEGQHPFSLTNIASVLDVAAKLE 1301 G RI+ S+GSG S FS + + I D+A K+E Sbjct: 289 KPGDRILWVSFGSGAGSDAFSIVVQDA--------IEEKRDLAPKVE 327
>Q5JFL6:Y181_PYRKO UPF0219 protein TK0181 - Pyrococcus kodakaraensis (Thermococcus| kodakaraensis) Length = 350 Score = 59.3 bits (142), Expect = 5e-08 Identities = 97/422 (22%), Positives = 159/422 (37%), Gaps = 11/422 (2%) Frame = +3 Query: 129 KDVGILAMDMYFPPTCVQQEALEVHDGAS----KGKYTIGLGQDCMAFCSEVEDVISMSL 296 ++VGI+ Y P ++ E + G S + K GL ED I++ + Sbjct: 9 REVGIIGYGAYVPMYRIKAEEIGRVWGVSSFPIQEKSVPGLD----------EDTITIGI 58 Query: 297 TVVKSLLEKYHIDPKLIGRLEVGSETVIDKSKSIKTWLMQIFEESGNT-DIEGVDSSNAC 473 ++ L++ IDPKLI + +G+E+ K ++K I E G T D++ D AC Sbjct: 59 EAARNALKRAQIDPKLIRAIWLGTES---KPYAVKPSGTVIAEAIGATPDLDAADFEFAC 115 Query: 474 YGGTAALLNCVNWVESRCWDGRYGLVVCTDSAVYAEGP----ARPTGGAAAIAMLIGPNA 641 GT A+ + +V S D Y + + D++ G GGAA I Sbjct: 116 KAGTEAIQAAIGFVGSGMAD--YAMAIGADTSQGRPGDHLEFTAAAGGAAYILAPKSSET 173 Query: 642 PISFESKYRASHMAHVYDFYKPDLASEYPVVDGKLSQTCYLMALDSCYRQYCAKYEKLVG 821 FE+ Y S++ DF++ YP + + + Y K + Sbjct: 174 LAYFEASY--SYVTDTPDFWRRQ-HEHYPRHGNRFTG-------EPAYFHQIINAAKTLM 223 Query: 822 EQ--FSISDADYCVFHSPYNKLVQKSFARLYFNDFMRNCSSVDNDAKEKLQPFANLTSEE 995 E+ ++ +D DY VFH P K F + + KEK+ P Sbjct: 224 EELGYTPNDFDYAVFHQPNVK-------------FPLTAAKILGFPKEKVLP-------- 262 Query: 996 SYQSRDLEKGSQQLAKHLYDIKVQPSTLLPKQIGNMYTASLYAALASVIYNKHASLNGQR 1175 LL IGN Y+ + +++V+ + G R Sbjct: 263 --------------------------GLLSGIIGNTYSGATLVGVSAVL---DIAKPGDR 293 Query: 1176 IVMFSYGSGLTSTMFSFKLNEGQHPFSLTNIASVLDVAAKLESRHVTSPEKFIDTLKLME 1355 I+ S+GSG S FS + + I D+A K + + +K+ID + Sbjct: 294 ILWVSFGSGAGSDAFSLVVQDA--------IEEKRDLAPK--TMDYVNRKKYIDYALYAK 343 Query: 1356 HR 1361 HR Sbjct: 344 HR 345
>Q9HI87:Y1455_THEAC UPF0219 protein Ta1455 - Thermoplasma acidophilum| Length = 351 Score = 59.3 bits (142), Expect = 5e-08 Identities = 82/371 (22%), Positives = 140/371 (37%), Gaps = 4/371 (1%) Frame = +3 Query: 273 EDVISMSLTVVKSLLEKYHIDPKLIGRLEVGSETVIDKSKSIKTWLMQIFEESG-NTDIE 449 EDV ++S+ ++ L++ IDPK IG + VGSE+ ++K + G + + Sbjct: 48 EDVATISVEAARNALKRKKIDPKEIGAIYVGSES---HPYAVKPTATIVGSAIGVDFSLF 104 Query: 450 GVDSSNACYGGTAALLNCVNWVESRCWDGRYGLVVCTDSAVYAEGPA-RPTGGAAAIAML 626 D AC GTA + N V+S +YGL + D++ A G A + A A + Sbjct: 105 AADYEFACKAGTAGMQNVKAMVDSGMI--KYGLAIGADTSQGAPGDALEYSASAGGTAFI 162 Query: 627 IGPNAPISFESKYRASHMAHVYDFYKPDLASEYPVVDGKLSQTCYLMALDSCYRQYCAKY 806 IG + I+ E S + DF++ + YP + + + Y ++ Sbjct: 163 IGKDDTIA-EINSTLSVASDTPDFWRRE-GQPYPSHGERFTG-------EPAYFRHVITA 213 Query: 807 EKLVGEQFSI--SDADYCVFHSPYNKLVQKSFARLYFNDFMRNCSSVDNDAKEKLQPFAN 980 K++ E+ D DY VFH P K ++ L F + Sbjct: 214 AKMMMERMETQPKDYDYVVFHQPNGKFPTRAAKMLGFEE--------------------- 252 Query: 981 LTSEESYQSRDLEKGSQQLAKHLYDIKVQPSTLLPKQIGNMYTASLYAALASVIYNKHAS 1160 K LL IGN Y+ S+ L+S++ S Sbjct: 253 --------------------------KQYKDGLLTPYIGNTYSGSMMTGLSSIL---DVS 283 Query: 1161 LNGQRIVMFSYGSGLTSTMFSFKLNEGQHPFSLTNIASVLDVAAKLESRHVTSPEKFIDT 1340 G I+ S+GSG S F +V D +++ + +K ++ Sbjct: 284 KPGDHILAVSFGSGAGSDAFDI---------------TVTDRIEEMDRNRAPTIKKMLEN 328 Query: 1341 LKLMEHRYGAK 1373 +K +++ AK Sbjct: 329 VKWVDYAIYAK 339
>Q6L233:Y384_PICTO UPF0219 protein PTO0384 - Picrophilus torridus| Length = 351 Score = 57.8 bits (138), Expect = 2e-07 Identities = 85/369 (23%), Positives = 136/369 (36%), Gaps = 2/369 (0%) Frame = +3 Query: 138 GILAMDMYFPPTCVQQEALEVHDGASKGKYTIGLGQDCMAFCSEVEDVISMSLTVVKSLL 317 GI+ Y P ++ E + G K G+ + EDV ++S+ ++ L Sbjct: 3 GIVTYGSYIPRYRIRPEEIARVWGEDPEKMKNGIFILSKSVPGPDEDVATISVEAARNAL 62 Query: 318 EKYHIDPKLIGRLEVGSETVIDKSKSIKTWLMQIFEESGNTDIEGVDSSNACYGGTAALL 497 ++ +IDP IG + +GSE+ K T + T D AC GTAA+ Sbjct: 63 KRSNIDPNDIGAIYIGSESHPYAVKPTATIVAAAIGMPFRT--FAADYEFACKAGTAAMQ 120 Query: 498 NCVNWVESRCWDGRYGLVVCTDSAVYAEGPA-RPTGGAAAIAMLIGPNAPISFESKYRAS 674 N V+S +YG+ + +D++ A G A T A AM+IG + I+ E S Sbjct: 121 NIKAMVDSNMI--KYGMAIGSDTSQGAPGDALEYTASAGGTAMVIGRDNVIA-EINKTIS 177 Query: 675 HMAHVYDFYKPDLASEYPVVDGKLS-QTCYLMALDSCYRQYCAKYEKLVGEQFSISDADY 851 DF++ + YP + + + Y + R ++ D DY Sbjct: 178 VATDTPDFWRRE-GEPYPKHGERFTGEPGYFKHVIGAARDIMSELNT------KPDDYDY 230 Query: 852 CVFHSPYNKLVQKSFARLYFNDFMRNCSSVDNDAKEKLQPFANLTSEESYQSRDLEKGSQ 1031 VFH P K ++ L F EE Y+ Sbjct: 231 VVFHQPNGKFPTRAAKILGFR-------------------------EEQYR--------- 256 Query: 1032 QLAKHLYDIKVQPSTLLPKQIGNMYTASLYAALASVIYNKHASLNGQRIVMFSYGSGLTS 1211 L+ IGN Y+ S L++++ S G RI+ S+GSG S Sbjct: 257 -------------EGLITPYIGNTYSGSTMTGLSAIL---DVSRPGDRILAVSFGSGAGS 300 Query: 1212 TMFSFKLNE 1238 F + + Sbjct: 301 DAFDITVTD 309
>Q971K8:Y1349_SULTO UPF0219 protein ST1349 - Sulfolobus tokodaii| Length = 348 Score = 57.4 bits (137), Expect = 2e-07 Identities = 90/375 (24%), Positives = 137/375 (36%), Gaps = 5/375 (1%) Frame = +3 Query: 264 SEVEDVISMSLTVVKSLLEKYHIDPKLIGRLEVGSETVIDKSKSIKTWLMQIFEESGNTD 443 S ED +M+ ++ L + IDP I + GSE+ + K T ++ S T Sbjct: 45 SHDEDSTTMAWEAARNALMRAKIDPSEIKAVLFGSESKVYAVKPTSTIIIDSLGISHET- 103 Query: 444 IEGVDSSNACYGGTAALLNCVNWVESRCWDGRYGLVVCTDSAVYAEGPARPTGGAAA-IA 620 D AC + L VE+ +YGLV+ +D A G AAA +A Sbjct: 104 -LSADLEFACRAASVGLRLLSGMVEANRI--KYGLVIGSDVAQSNPGDVLELSSAAASVA 160 Query: 621 MLIGPNAPISFESKYRASHMAHVYDFYKPDLASEYPVV-DGKLSQTCYLMALDSCYRQYC 797 ++GP S +Y S+ + DF++ D YP+ + + Y + S + Sbjct: 161 YIVGPADESSAIIEYATSYTTDMPDFWRRD-GMPYPLHGEAFTGEPAYFAHIISAVQLL- 218 Query: 798 AKYEKLVGEQFSISDADYCVFHSPYNKLVQKSFARLYFNDFMRNCSSVDNDAKEKLQPFA 977 L +SISD DY VFH P K Sbjct: 219 -----LKEGGYSISDFDYFVFHQPNGKF-------------------------------- 241 Query: 978 NLTSEESYQSRDLEKGSQQLAKHL-YDIKVQPSTLLPKQIGNMYTASLYAALASVIYNKH 1154 Q+AK L ++ L+ IGN Y AS LA V+ Sbjct: 242 ----------------PLQVAKKLGVPLEKVKEGLVSPYIGNPYNASALLGLAKVL---D 282 Query: 1155 ASLNGQRIVMFSYGSGLTSTMFSFKLNEGQHPFSLTNIASVLDVAAKLESRHVTSP--EK 1328 + GQRI++ +GSG S FS + + K+E R +P E Sbjct: 283 IAKPGQRILVAPFGSGAGSDAFSILVTD------------------KIEERQKLAPRVED 324 Query: 1329 FIDTLKLMEHRYGAK 1373 +I+ K++ + AK Sbjct: 325 YINNKKVISYSVYAK 339
>Q97CG9:Y132_THEVO UPF0219 protein TV0132 - Thermoplasma volcanium| Length = 351 Score = 55.5 bits (132), Expect = 8e-07 Identities = 75/326 (23%), Positives = 126/326 (38%), Gaps = 4/326 (1%) Frame = +3 Query: 273 EDVISMSLTVVKSLLEKYHIDPKLIGRLEVGSETVIDKSKSIKTWLMQIFEESG-NTDIE 449 EDV ++S+ ++ L++ I+PK IG + VGSE+ ++K + G + + Sbjct: 48 EDVATISVEAARNALKRKKINPKEIGAIYVGSES---HPYAVKPTATIVGSAIGVDFSLF 104 Query: 450 GVDSSNACYGGTAALLNCVNWVESRCWDGRYGLVVCTDSAVYAEGPA-RPTGGAAAIAML 626 D AC GTA + N V++ +YGL + D++ A G A + A A + Sbjct: 105 AADYEFACKAGTAGMQNVKAMVDAGMI--KYGLAIGADTSQGAPGDALEYSASAGGSAFI 162 Query: 627 IGPNAPISFESKYRASHMAHVYDFYKPDLASEYPVVDGKLSQTCYLMALDSCYRQYCAKY 806 IG + I+ E S + DF++ + YP + + + Y ++ Sbjct: 163 IGKDDVIA-EINSTLSVASDTPDFWRRE-GQPYPSHGERFTG-------EPAYFRHVVNA 213 Query: 807 EKLVGEQFSI--SDADYCVFHSPYNKLVQKSFARLYFNDFMRNCSSVDNDAKEKLQPFAN 980 K++ E+ D DY VFH P K ++ A Sbjct: 214 AKMMMERMETQPKDYDYVVFHQPNGKFPTRA---------------------------AK 246 Query: 981 LTSEESYQSRDLEKGSQQLAKHLYDIKVQPSTLLPKQIGNMYTASLYAALASVIYNKHAS 1160 L E Q +D L+ IGN Y+ S+ L+S++ S Sbjct: 247 LLGFEEKQYKD--------------------GLITPYIGNTYSGSMMTGLSSIL---DVS 283 Query: 1161 LNGQRIVMFSYGSGLTSTMFSFKLNE 1238 G I+ S+GSG S F + + Sbjct: 284 KPGDHILAVSFGSGAGSDAFDITVTD 309
>Q9YAS0:Y1873_AERPE UPF0219 protein APE_1873.1 - Aeropyrum pernix| Length = 361 Score = 51.6 bits (122), Expect = 1e-05 Identities = 77/321 (23%), Positives = 122/321 (38%), Gaps = 4/321 (1%) Frame = +3 Query: 273 EDVISMSLTVVKSLLEKYHIDPKLIGRLEVGSETVIDKSKSIKTWLMQIFEESGNTDIE- 449 ED +M + ++ + + +DP IG + GSE+ K ++K I E G T + Sbjct: 60 EDSTTMGVEAARNAIARARVDPASIGAVFFGSES---KPYAVKPSATIIAEALGITPVTM 116 Query: 450 GVDSSNACYGGTAALLNCVNWVESRCWDGRYGLVVCTDSAVYAEGPARP-TGGAAAIAML 626 D AC + + + V S Y LVV +D+A + G + + A A + Sbjct: 117 ASDLEFACRAASEGMRASIGLVASGVVG--YTLVVGSDTAQASPGDVLEFSASSGAAAFV 174 Query: 627 IGPN--APISFESKYRASHMAHVYDFYKPDLASEYPVVDGKLSQTCYLMALDSCYRQYCA 800 IGP+ A FES + +++ DF++ L +G + Y ++S + Sbjct: 175 IGPSKGAAAVFESSF--TYVTDTPDFWRRGLKPYPSHGEGFTGEPAYFHHIESAVK---G 229 Query: 801 KYEKLVGEQFSISDADYCVFHSPYNKLVQKSFARLYFNDFMRNCSSVDNDAKEKLQPFAN 980 +EK S D DY +FH P K K +L F Sbjct: 230 LFEK---TGLSPGDFDYAIFHQPNGKFPVKVAKKLGF----------------------- 263 Query: 981 LTSEESYQSRDLEKGSQQLAKHLYDIKVQPSTLLPKQIGNMYTASLYAALASVIYNKHAS 1160 T E+ V+P + P IGN Y AS L V+ + Sbjct: 264 -TMEQ----------------------VKPGLVTP-FIGNTYNASALLGLVKVL---DVA 296 Query: 1161 LNGQRIVMFSYGSGLTSTMFS 1223 G RI++ +GSG S +S Sbjct: 297 KPGDRILVAPFGSGAGSDAYS 317
>Q8PYJ0:Y871_METMA UPF0219 protein MM_0871 - Methanosarcina mazei (Methanosarcina| frisia) Length = 349 Score = 51.2 bits (121), Expect = 1e-05 Identities = 75/328 (22%), Positives = 117/328 (35%), Gaps = 6/328 (1%) Frame = +3 Query: 273 EDVISMSLTVVKSLLEKYHIDPKLIGRLEVGSETVIDKSKSIKTWLMQIFEESGNTDIEG 452 ED ++++ ++ + + +DP IG + GSE+ K T + Q + Sbjct: 49 EDAATIAVEAARNAMIRSGVDPSRIGAVYTGSESHPYAVKPTSTIVAQAI--GATPQMTA 106 Query: 453 VDSSNACYGGTAALLNCVNWVESRCWDGRYGLVVCTDSAVYAEGPARP-TGGAAAIAMLI 629 D AC GTAA+ C+ V S D GL + D + A A T A +A LI Sbjct: 107 ADFEFACKAGTAAVQACMGLVGSGMVD--LGLAIGADVSQGAPSDALEYTAAAGGVACLI 164 Query: 630 GPNAP---ISFESKYRASHMAHVYDFYKPDLASEYPVVDGKLSQTCYLMALDSCYRQYCA 800 G N E Y S DF++ + YP G+ + + Y ++ Sbjct: 165 GRNESELAAIIEDTY--SFTTDTPDFWRRE-GMPYPEHGGRFTG-------EPGYFKHVT 214 Query: 801 KYEKLVGEQFSIS--DADYCVFHSPYNKLVQKSFARLYFNDFMRNCSSVDNDAKEKLQPF 974 K + E+ D DY VFH P K K+ L F Sbjct: 215 NGAKGLLEKLGAKPEDYDYAVFHQPNGKFPSKAAKMLGFT-------------------- 254 Query: 975 ANLTSEESYQSRDLEKGSQQLAKHLYDIKVQPSTLLPKQIGNMYTASLYAALASVIYNKH 1154 ++ P ++PK IGN Y+ S +A+ + Sbjct: 255 --------------------------KAQITPGLVVPK-IGNTYSGSCLMGIAATL---D 284 Query: 1155 ASLNGQRIVMFSYGSGLTSTMFSFKLNE 1238 + G RI ++GSG S FS + + Sbjct: 285 QAKPGDRIFATAFGSGAGSDAFSITVTD 312
>Q8TIV0:Y4041_METAC UPF0219 protein MA_4041 - Methanosarcina acetivorans| Length = 349 Score = 48.9 bits (115), Expect = 7e-05 Identities = 74/328 (22%), Positives = 116/328 (35%), Gaps = 6/328 (1%) Frame = +3 Query: 273 EDVISMSLTVVKSLLEKYHIDPKLIGRLEVGSETVIDKSKSIKTWLMQIFEESGNTDIEG 452 ED ++++ + + + +DP IG + GSE+ K T + Q ++ Sbjct: 49 EDAATIAVEAARYAMARSGVDPSRIGAVYTGSESHPYAVKPTSTIVAQAI--GATPEMTA 106 Query: 453 VDSSNACYGGTAALLNCVNWVESRCWDGRYGLVVCTDSAVYAEGPARP-TGGAAAIAMLI 629 D AC GTAA+ C+ V S D GL + D + A A T A +A LI Sbjct: 107 ADFEFACKAGTAAVQACMGLVGSGMID--LGLAIGADVSQGAPSDALEYTAAAGGVACLI 164 Query: 630 G---PNAPISFESKYRASHMAHVYDFYKPDLASEYPVVDGKLSQTCYLMALDSCYRQYCA 800 G E Y S DF++ + YP G+ + + Y ++ Sbjct: 165 GRKESELAAIIEDTY--SFTTDTPDFWRRE-GMPYPEHGGRFTG-------EPGYFKHVT 214 Query: 801 KYEKLVGEQFSIS--DADYCVFHSPYNKLVQKSFARLYFNDFMRNCSSVDNDAKEKLQPF 974 K + E+ D DY VFH P K K+ L F Sbjct: 215 NGAKGLLEKLGTKPEDYDYAVFHQPNGKFPSKAAKILGFT-------------------- 254 Query: 975 ANLTSEESYQSRDLEKGSQQLAKHLYDIKVQPSTLLPKQIGNMYTASLYAALASVIYNKH 1154 ++ P ++PK IGN Y+ S +A+ + Sbjct: 255 --------------------------KAQITPGLVVPK-IGNTYSGSCLMGIAATL---D 284 Query: 1155 ASLNGQRIVMFSYGSGLTSTMFSFKLNE 1238 + G RI ++GSG S FS + + Sbjct: 285 QAKPGDRIFATAFGSGAGSDAFSITVTD 312
>Q9UWU0:Y535_SULSO UPF0219 protein SSO0535 - Sulfolobus solfataricus| Length = 350 Score = 46.2 bits (108), Expect = 5e-04 Identities = 87/373 (23%), Positives = 138/373 (36%), Gaps = 5/373 (1%) Frame = +3 Query: 138 GILAMDMYFPPTCVQQEALEVHDGASKGKY-TIGLGQDCMAFCSEVEDVISMSLTVVKSL 314 GIL Y P ++ E + G + ++GL + + E I+ ++ + Sbjct: 4 GILGWGAYIPRYRIKVEDIAKMWGYDEAVVKSLGLTEKSVPGHDEDSTTIAWESSI--NA 61 Query: 315 LEKYHIDPKLIGRLEVGSETVIDKSKSIKTWLMQIFEESGNTDIEGVDSSNACYGGTAAL 494 +++ +D I + GSE+ + K T L+ N D AC + L Sbjct: 62 IKRAQVDTSKIRLVLFGSESKVYAVKPTSTILIDAL--GINNYSATADMEFACRAASVGL 119 Query: 495 LNCVNWVESRCWDGRYGLVVCTDSAVYAEGPARPTGGAAA-IAMLIGPNAPISFES--KY 665 ++V + Y LV+ D+A G AAA +A ++G + +Y Sbjct: 120 RLASSFVLHN--NDSYALVIGADTAQSNPGDVLELSSAAAGVAFVVGKTDEKHSAAVIEY 177 Query: 666 RASHMAHVYDFYKPDLASEYPVV-DGKLSQTCYLMALDSCYRQYCAKYEKLVGEQFSISD 842 +S+ + DF++ D + YPV +G + Y + S A + L ISD Sbjct: 178 SSSYTSDTPDFWRRD-GTPYPVHGEGFTGEPAYFHHIIS------AVNDLLQNSGLKISD 230 Query: 843 ADYCVFHSPYNKLVQKSFARLYFNDFMRNCSSVDNDAKEKLQPFANLTSEESYQSRDLEK 1022 DY VFH P K + +L LEK Sbjct: 231 FDYFVFHQPNGKFPIQVAKKL---------------------------------GVPLEK 257 Query: 1023 GSQQLAKHLYDIKVQPSTLLPKQIGNMYTASLYAALASVIYNKHASLNGQRIVMFSYGSG 1202 Q L V P IGN Y AS LA V+ + G+RI++ +GSG Sbjct: 258 VKQGL--------VSP------YIGNPYNASALLGLAKVL---DIAKPGERILVAPFGSG 300 Query: 1203 LTSTMFSFKLNEG 1241 S FS ++EG Sbjct: 301 AGSDAFSILVSEG 313
>P44809:HGP2_HAEIN Probable hemoglobin and hemoglobin-haptoglobin-binding protein 2| precursor - Haemophilus influenzae Length = 999 Score = 32.7 bits (73), Expect = 5.3 Identities = 43/169 (25%), Positives = 68/169 (40%), Gaps = 8/169 (4%) Frame = +3 Query: 555 CTDSAVYAEGPARPTGGAAAIAMLIGPN-APISFESKYRASHMAH-VYDFYKPDLASEYP 728 C + EG PTG + + + + FE K + + YDF K + ++ Sbjct: 379 CDAGVRHCEGTDNPTGLKVTNGKITRRDGSDLQFEEKNNTAKSSDKTYDF-KKFIDTDKR 437 Query: 729 VVDGKL-----SQTCYLMALDSCYRQYCAKYEKLVGEQFSISDADYCVFHSPYNKLVQKS 893 V+D KL S T Y ++ +C AK + G + D + +L K Sbjct: 438 VIDDKLVLNNPSDTWYDCSIFNCENN--AKIKVFKGNNYYGYDGKWKEVDLEIKELNGKK 495 Query: 894 FARLYFNDFMRNCSSVDNDAKEK-LQPFANLTSEESYQSRDLEKGSQQL 1037 FA++ DND K K + P + E +Q RDL+ +QQL Sbjct: 496 FAKIK-----------DNDRKIKSILPSSPGYLERLWQERDLDTNTQQL 533
>P54576:MCPC_BACSU Methyl-accepting chemotaxis protein mcpC - Bacillus subtilis| Length = 654 Score = 32.3 bits (72), Expect = 6.9 Identities = 17/42 (40%), Positives = 24/42 (57%) Frame = +3 Query: 369 ETVIDKSKSIKTWLMQIFEESGNTDIEGVDSSNACYGGTAAL 494 ET+ +KS+S+ T + QI EE+G S +A Y G AL Sbjct: 398 ETINEKSESLSTKIRQIAEEAGGIKERSKSSEDASYKGLHAL 439
>P83626:TNR26_MOUSE Tumor necrosis factor receptor superfamily member 26 precursor -| Mus musculus (Mouse) Length = 204 Score = 32.0 bits (71), Expect = 9.0 Identities = 29/128 (22%), Positives = 53/128 (41%), Gaps = 7/128 (5%) Frame = -3 Query: 812 LLILGTILSIARIQSHKVARLR*FPINNRVFTCKIRLIEIVNMSHVRSSIFTFKRNRCIW 633 LL+LG +L +A N + CKI + N+ ++ S T+ RN C Sbjct: 7 LLLLGLLLRVAVCSV------------NTITLCKIGEFKHENLCCLQCSAGTYLRNPCQE 54 Query: 632 TNKHSNCSSS------TRRPSWSLCINRAICADHKAVASIPASTFDPIHTVQQGS-CPTI 474 + S C+ + S C ++C D + + + T D + +QG+ C + Sbjct: 55 NHNKSECAPCDSEHFIDHKNRESECFPCSVCRDDQEEVAKCSRTADRVCQCKQGTYCDSE 114 Query: 473 TCVTRVNS 450 C+ R ++ Sbjct: 115 NCLERCHT 122 Database: uniprot_sprot.fasta.out Posted date: Jul 19, 2007 5:58 PM Number of letters in database: 100,686,439 Number of sequences in database: 274,295 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 274295 Number of Hits to DB: 313,715,946 Number of extensions: 6802096 Number of successful extensions: 17838 Number of sequences better than 10.0: 40 Number of HSP's gapped: 17754 Number of HSP's successfully gapped: 45 Length of query: 615 Length of database: 100,686,439 Length adjustment: 119 Effective length of query: 496 Effective length of database: 68,045,334 Effective search space: 33750485664 Effective search space used: 33750485664 Neighboring words threshold: 12 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
