Clone Name | FLbaf95m06 |
---|---|
Clone Library Name | barley_pub |
>P13443:DHGY_CUCSA Glycerate dehydrogenase - Cucumis sativus (Cucumber)| Length = 382 Score = 650 bits (1677), Expect = 0.0 Identities = 316/380 (83%), Positives = 342/380 (90%) Frame = +2 Query: 170 MAKPISIEVWNPSGKYRVVSTKSMPGTRWIKLLTDNDCRLEICTEKKTILSVDDILALIG 349 MAKP+ IEVWNP+GKYRVVSTK MPGTRWI LL + DCR+EICTEKKTILSV+DILALIG Sbjct: 1 MAKPVQIEVWNPNGKYRVVSTKPMPGTRWINLLIEQDCRVEICTEKKTILSVEDILALIG 60 Query: 350 DHCHGVIGQLTEDWGEVLFSALKRAGGTAFSNMAVGYNNVDVDAANKNGIAIGNTPGVLT 529 D C GVIGQLTEDWGEVLFSAL RAGG AFSNMAVGYNNVDV+AANK G+A+GNTPGVLT Sbjct: 61 DKCDGVIGQLTEDWGEVLFSALSRAGGKAFSNMAVGYNNVDVNAANKYGVAVGNTPGVLT 120 Query: 530 ETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAY 709 ETT RRIVEAD+FMRAG YDGWLP+LFVGNLLKGQTVGVIGAGRIGSAY Sbjct: 121 ETTAELAASLSLAAARRIVEADEFMRAGRYDGWLPNLFVGNLLKGQTVGVIGAGRIGSAY 180 Query: 710 ARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADVI 889 ARMM+EGFKMNLIYFDLYQSTRLEKFVTAYG+FLKANGE PVTW+RASSM+EVLREADVI Sbjct: 181 ARMMVEGFKMNLIYFDLYQSTRLEKFVTAYGEFLKANGEAPVTWRRASSMDEVLREADVI 240 Query: 890 SLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFE 1069 SLHPVLDKTT+HL+N E L MKK+A+L+N SRGPVIDE ALV+HL+ NPMFRVGLDVFE Sbjct: 241 SLHPVLDKTTFHLVNKESLKAMKKDAILINCSRGPVIDEAALVDHLRDNPMFRVGLDVFE 300 Query: 1070 DEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKGYPVWGNPNAVEPFL 1249 DEPYMKPGLA+MKNA++VPHIASASKWTREGMATLAALNVLGKIKGYPVW +PN VEPFL Sbjct: 301 DEPYMKPGLADMKNAIIVPHIASASKWTREGMATLAALNVLGKIKGYPVWSDPNRVEPFL 360 Query: 1250 DEEATPPPACPSIVNAKQLG 1309 DE +PP A PSIVNAK LG Sbjct: 361 DENVSPPAASPSIVNAKALG 380
>Q9C4M5:GYAR_THELI Glyoxylate reductase - Thermococcus litoralis| Length = 331 Score = 192 bits (489), Expect = 3e-48 Identities = 111/258 (43%), Positives = 152/258 (58%), Gaps = 5/258 (1%) Frame = +2 Query: 449 AVGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYD-- 622 AVGY+N+D++ A K GI + NTPGVLT+ T RRIVEAD F+R+G + Sbjct: 75 AVGYDNIDIEEATKRGIYVTNTPGVLTDATADLAFALLLAVARRIVEADAFVRSGEWKKS 134 Query: 623 --GWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTA 796 GW P +F+G LKG+T+G++G GRIG A A+ +GF M +IY+ + E+ + A Sbjct: 135 EVGWHPLMFLGYGLKGKTLGIVGFGRIGQALAKRA-KGFGMKIIYYSRTRKPEAEEEIGA 193 Query: 797 -YGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVL 973 Y F E +L+E+D ISLH L K TYH+I + L +MK A+L Sbjct: 194 EYVDF-----------------ETLLKESDFISLHVPLTKETYHMIGEKELKLMKPNAIL 236 Query: 974 VNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWT 1153 +N SRG V+D AL++ LK + GLDVFE+EPY L ++KN V+ PHI SA+ Sbjct: 237 INTSRGAVVDTNALIKALKEGWIAGAGLDVFEEEPYYNEELFKLKNVVLAPHIGSATHEA 296 Query: 1154 REGMATLAALNVLGKIKG 1207 REGMA L A N++ KG Sbjct: 297 REGMAELVAKNLIAFAKG 314
>O58320:GYAR_PYRHO Glyoxylate reductase - Pyrococcus horikoshii| Length = 334 Score = 183 bits (465), Expect = 2e-45 Identities = 120/336 (35%), Positives = 182/336 (54%), Gaps = 4/336 (1%) Frame = +2 Query: 212 KYRVVSTKSMPGTRWIKLLTDNDCRLEICTEKKTILSVDDILALIGDHCHGVIGQLTEDW 391 K +V T+ +P IK+L D + +E+ ++K I +IL ++ L+E Sbjct: 2 KPKVFITREIPEVG-IKMLED-EFEVEVWGDEKEIPR--EILLKKVKEVDALVTMLSERI 57 Query: 392 GEVLFSALKRAGGTAFSNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXX 571 + +F + A N AVGY+N+D++ A K GI + NTP VLT+ T Sbjct: 58 DKEVFENAPKLRIVA--NYAVGYDNIDIEEATKRGIYVTNTPDVLTDATADLAFALLLAT 115 Query: 572 XRRIVEADQFMRAGLYD----GWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKM 739 R +V+ D+F+R+G + W P F+G + G+T+G+IG GRIG A A+ +GF M Sbjct: 116 ARHVVKGDRFVRSGEWKKRGVAWHPKWFLGYDVYGKTIGIIGLGRIGQAIAKRA-KGFNM 174 Query: 740 NLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTT 919 ++Y+ + +E+ + A +E++LRE+D + L L + T Sbjct: 175 RILYYSRTRKEEVERELNA----------------EFKPLEDLLRESDFVVLAVPLTRET 218 Query: 920 YHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGLA 1099 YHLIN ERL +MKK A+L+N +RG V+D ALV+ LK + GLDVFE+EPY L Sbjct: 219 YHLINEERLKLMKKTAILINIARGKVVDTNALVKALKEGWIAGAGLDVFEEEPYYNEELF 278 Query: 1100 EMKNAVVVPHIASASKWTREGMATLAALNVLGKIKG 1207 ++ N V+ PHI SAS REGMA L A N++ +G Sbjct: 279 KLDNVVLTPHIGSASFGAREGMAELVAKNLIAFKRG 314
>Q9UYR1:GYAR_PYRAB Glyoxylate reductase - Pyrococcus abyssi| Length = 335 Score = 183 bits (465), Expect = 2e-45 Identities = 104/260 (40%), Positives = 149/260 (57%), Gaps = 4/260 (1%) Frame = +2 Query: 440 SNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLY 619 +N AVGY+N+DV+ A K GI + NTPGVLT+ T R +V+ D+F R+G + Sbjct: 73 ANYAVGYDNIDVEEATKRGIYVTNTPGVLTDATADLAFALLLATARHLVKGDKFTRSGEW 132 Query: 620 D----GWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKF 787 W P F+G + G+T+G+IG GRIG A A+ GF M ++Y+ + +EK Sbjct: 133 KKRGVAWHPKWFLGYDVYGKTIGIIGFGRIGQAIAKRA-RGFDMRILYYSRTRKPEVEKE 191 Query: 788 VTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEA 967 + A ++E+LRE+D + L L+K TYH+IN ERL MMK+ A Sbjct: 192 LNA----------------EFKPLDELLRESDFVVLAVPLNKETYHMINEERLKMMKRTA 235 Query: 968 VLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASK 1147 +L+N +RG VID AL++ LK + GLDV+E+EPY L + N V+ PHI SA+ Sbjct: 236 ILINVARGKVIDTKALIKALKEGWIAGAGLDVYEEEPYYNEELFSLDNVVLTPHIGSATF 295 Query: 1148 WTREGMATLAALNVLGKIKG 1207 REGMA L A N++ +G Sbjct: 296 GAREGMAKLVAENLIAFKRG 315
>Q5JEZ2:GYAR_PYRKO Glyoxylate reductase - Pyrococcus kodakaraensis (Thermococcus| kodakaraensis) Length = 333 Score = 180 bits (456), Expect = 2e-44 Identities = 109/280 (38%), Positives = 155/280 (55%), Gaps = 4/280 (1%) Frame = +2 Query: 365 VIGQLTEDWGEVLFSALKRAGGTAFSNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTXX 544 ++ L+E +F A R A N AVGY+N+DV+ A + GI + NTP VLT+ T Sbjct: 49 LVTMLSERIDSEVFDAAPRLRIVA--NYAVGYDNIDVEEATRRGIYVTNTPDVLTDATAD 106 Query: 545 XXXXXXXXXXRRIVEADQFMRAGLYD----GWLPHLFVGNLLKGQTVGVIGAGRIGSAYA 712 RR++EAD F R+G + W P F+G + G+T+G++G GRIG A A Sbjct: 107 FAWTLLLATARRLIEADHFTRSGEWKRRGIAWHPRWFLGYDVYGKTIGIVGFGRIGQAVA 166 Query: 713 RMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADVIS 892 R GF M ++Y+ + EK + A S+E++LRE+D + Sbjct: 167 RRA-RGFGMRILYYSRSRKPEAEKELGA----------------EFRSLEDLLRESDFVV 209 Query: 893 LHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFED 1072 L L K T ++IN ERL +MKK A+LVN +RG V+D AL++ LK + GLDV+E+ Sbjct: 210 LAVPLTKETQYMINEERLRLMKKTAILVNIARGKVVDTKALMKALKEGWIAGAGLDVYEE 269 Query: 1073 EPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVL 1192 EPY L +KN V+ PHI SA+ REGMA L A N++ Sbjct: 270 EPYYNEELFSLKNVVLAPHIGSATYGAREGMAELVARNLI 309
>Q8U3Y2:GYAR_PYRFU Glyoxylate reductase - Pyrococcus furiosus| Length = 336 Score = 174 bits (440), Expect = 1e-42 Identities = 117/336 (34%), Positives = 180/336 (53%), Gaps = 4/336 (1%) Frame = +2 Query: 212 KYRVVSTKSMPGTRWIKLLTDNDCRLEICTEKKTILSVDDILALIGDHCHGVIGQLTEDW 391 K +V T+++P I +L + + +E+ E++ I + +L + D ++ L+E Sbjct: 2 KPKVFITRAIP-ENGINML-EEEFEVEVWEEEREIPR-EKLLEKVKD-VDALVTMLSERI 57 Query: 392 GEVLFSALKRAGGTAFSNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXX 571 + +F R A N AVGY+N+DV+ A + GI + NTP VLT T Sbjct: 58 DQEVFENAPRLRIVA--NYAVGYDNIDVEEATRRGIYVTNTPDVLTNATADHAFALLLAT 115 Query: 572 XRRIVEADQFMRAGLYD----GWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKM 739 R +V+ D+F+R+G + W P F+G L G+T+G++G GRIG A AR +GF M Sbjct: 116 ARHVVKGDKFVRSGEWKRKGIAWHPKWFLGYELYGKTIGIVGFGRIGQAIARRA-KGFNM 174 Query: 740 NLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTT 919 ++Y+ + ++ EK + A +EEVL+E+D + L L K T Sbjct: 175 RILYYSRTRKSQAEKELGA----------------EYRPLEEVLKESDFVILAVPLTKET 218 Query: 920 YHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGLA 1099 ++IN ERL +MK A+LVN +RG V+D AL++ LK + GLDVFE+EPY L Sbjct: 219 MYMINEERLKLMKPTAILVNIARGKVVDTKALIKALKEGWIAGAGLDVFEEEPYYNEELF 278 Query: 1100 EMKNAVVVPHIASASKWTREGMATLAALNVLGKIKG 1207 + N V+ PHI SA+ RE MA L A N++ +G Sbjct: 279 SLDNVVLTPHIGSATFEAREAMAELVARNLIAFKRG 314
>Q9YAW4:GYAR_AERPE Glyoxylate reductase - Aeropyrum pernix| Length = 335 Score = 170 bits (430), Expect = 2e-41 Identities = 104/262 (39%), Positives = 149/262 (56%), Gaps = 6/262 (2%) Frame = +2 Query: 440 SNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAG-- 613 + MAVG++N+DV+ A + GI + NTPGVLTE T RR+VEAD F+R G Sbjct: 73 AQMAVGFDNIDVECATRLGIYVTNTPGVLTEATAEFTWALILAAARRVVEADHFVRWGEW 132 Query: 614 --LYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKF 787 L GW P + +G L+G+T+G++G GRIGS A + + F M +IY + +EK Sbjct: 133 WRLRTGWHPMMMLGVELRGKTLGILGMGRIGSRVAEIG-KAFGMRIIYHSRSRKREIEKE 191 Query: 788 VTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEA 967 + A S+E++LRE+D++S+H L T HLI L +MKK A Sbjct: 192 LGA----------------EYRSLEDLLRESDILSIHLPLTDETRHLIGESELKLMKKTA 235 Query: 968 VLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPG--LAEMKNAVVVPHIASA 1141 +LVN RG ++D ALV+ L+ + LDVFE+EP + P L KN V+ PH ASA Sbjct: 236 ILVNTGRGAIVDTGALVKALREGWIAAAALDVFEEEP-LNPNHPLTAFKNVVLAPHAASA 294 Query: 1142 SKWTREGMATLAALNVLGKIKG 1207 ++ TR MA +AA N++ +G Sbjct: 295 TRETRLRMAMMAAENLVAFAQG 316
>P37666:TKRA_ECOLI 2-ketogluconate reductase - Escherichia coli| Length = 324 Score = 143 bits (360), Expect = 2e-33 Identities = 91/259 (35%), Positives = 132/259 (50%), Gaps = 1/259 (0%) Frame = +2 Query: 434 AFSNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAG 613 A S ++VGY+N DVDA I + +TP VLTET RR+VE + ++AG Sbjct: 69 ATSTISVGYDNFDVDALTARKILLMHTPTVLTETVADTLMALVLSTARRVVEVAERVKAG 128 Query: 614 LYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVT 793 + + + G + +T+G++G GRIG A A+ GF M ++Y E+ Sbjct: 129 EWTASIGPDWYGTDVHHKTLGIVGMGRIGMALAQRAHFGFNMPILYNARRHHKEAEERFN 188 Query: 794 AYGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVL 973 A R ++ +L+E+D + L L T+HL E+ A MK A+ Sbjct: 189 A----------------RYCDLDTLLQESDFVCLILPLTDETHHLFGAEQFAKMKSSAIF 232 Query: 974 VNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEPY-MKPGLAEMKNAVVVPHIASASKW 1150 +NA RGPV+DE AL+ L+ + GLDVFE EP + L M N V VPHI SA+ Sbjct: 233 INAGRGPVVDENALIAALQKGEIHAAGLDVFEQEPLSVDSPLLSMANVVAVPHIGSATHE 292 Query: 1151 TREGMATLAALNVLGKIKG 1207 TR GMA A N++ ++G Sbjct: 293 TRYGMAACAVDNLIDALQG 311
>P58220:TKRA_ECO57 2-ketogluconate reductase - Escherichia coli O157:H7| Length = 324 Score = 143 bits (360), Expect = 2e-33 Identities = 91/259 (35%), Positives = 132/259 (50%), Gaps = 1/259 (0%) Frame = +2 Query: 434 AFSNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAG 613 A S ++VGY+N DVDA I + +TP VLTET RR+VE + ++AG Sbjct: 69 ATSTISVGYDNFDVDALTARKILLMHTPTVLTETVADTLMALVLSTARRVVEVAERVKAG 128 Query: 614 LYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVT 793 + + + G + +T+G++G GRIG A A+ GF M ++Y E+ Sbjct: 129 EWTASIGPDWYGTDVHHKTLGIVGMGRIGMALAQRAHFGFNMPILYNARRHHKEAEERFN 188 Query: 794 AYGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVL 973 A R ++ +L+E+D + L L T+HL E+ A MK A+ Sbjct: 189 A----------------RYCDLDTLLQESDFVCLILPLTDETHHLFGAEQFAKMKSSAIF 232 Query: 974 VNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEPY-MKPGLAEMKNAVVVPHIASASKW 1150 +NA RGPV+DE AL+ L+ + GLDVFE EP + L M N V VPHI SA+ Sbjct: 233 INAGRGPVVDENALIAALQKGEIHAAGLDVFEQEPLSVDSPLLSMANVVAVPHIGSATHE 292 Query: 1151 TREGMATLAALNVLGKIKG 1207 TR GMA A N++ ++G Sbjct: 293 TRYGMAACAVDNLIDALQG 311
>P58000:TKRA_ENTAG 2-ketogluconate reductase - Enterobacter agglomerans (Erwinia| herbicola) (Pantoea agglomerans) Length = 323 Score = 142 bits (359), Expect = 3e-33 Identities = 91/259 (35%), Positives = 136/259 (52%), Gaps = 1/259 (0%) Frame = +2 Query: 434 AFSNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAG 613 A S ++VGY+N DV+A N+ GI + +TP VLTET RR+VE + ++AG Sbjct: 68 AASTISVGYDNFDVEALNQRGIVLIDTPTVLTETVADTMMALVLSSARRVVEVAERVKAG 127 Query: 614 LYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVT 793 + + + G + + +G++G GRIG A A+ GF M ++Y E Sbjct: 128 EWRRSIGPDWFGIDVHHKKMGILGMGRIGLALAQRAHHGFGMPILYNARKHHEEAESRFN 187 Query: 794 AYGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVL 973 A + ++ +LRE+D + + L + T+H+I E+LA MK A+L Sbjct: 188 A----------------QYCDLDTLLRESDFLCISLPLTEQTHHMIGREQLAKMKPSAIL 231 Query: 974 VNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEPY-MKPGLAEMKNAVVVPHIASASKW 1150 +NA RGPV+DE AL+ LK + GLDVFE EP + L + N V +PHI SA+ Sbjct: 232 INAGRGPVVDEQALIAALKDKTIHAAGLDVFEQEPLPVDSELLTLPNVVALPHIGSATHE 291 Query: 1151 TREGMATLAALNVLGKIKG 1207 TR GMA A N++ + G Sbjct: 292 TRYGMARDAVDNLIAALAG 310
>O32264:TKRA_BACSU Probable 2-ketogluconate reductase - Bacillus subtilis| Length = 325 Score = 142 bits (357), Expect = 5e-33 Identities = 96/317 (30%), Positives = 145/317 (45%), Gaps = 23/317 (7%) Frame = +2 Query: 326 DDILALIGDHCHGVIGQLTEDWGEVLFSALKRAGGT----------------------AF 439 ++I A IG+HC + Q +VLF LK A G Sbjct: 14 EEIEAFIGEHCRYEVWQEDTLPSDVLFEKLKEAEGLLTSGTSGPSINRELLEHAPKLKVV 73 Query: 440 SNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLY 619 SN +VGY+N D++A + G+ +TP L +T RR+ E D+F+RAG + Sbjct: 74 SNQSVGYDNFDIEAMKERGVVGTHTPYTLDDTVADLAFSLILSSARRVAELDRFVRAGKW 133 Query: 620 DGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAY 799 G + QT+G+IG GRIG AR GF M ++Y + ++ E + Sbjct: 134 GTVEEEALFGIDVHHQTLGIIGMGRIGEQAARRAKFGFDMEVLYHNRHRKQETEDSIGV- 192 Query: 800 GQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVN 979 + + ++ +L ++D I L L TYH+I +MK A+ VN Sbjct: 193 ---------------KYAELDTLLEQSDFILLITPLTDETYHMIGEREFKLMKNSAIFVN 237 Query: 980 ASRGPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPG-LAEMKNAVVVPHIASASKWTR 1156 SRG +DE AL+ L+ + GLDV+E EP + L ++ N ++PHI SA+ R Sbjct: 238 ISRGKTVDEKALIRALQEGWIRGAGLDVYEKEPVTQDNPLLQLDNVTLLPHIGSATAKVR 297 Query: 1157 EGMATLAALNVLGKIKG 1207 M AA N+L I+G Sbjct: 298 FNMCKQAAENMLAAIQG 314
>O27051:SERA_METTH D-3-phosphoglycerate dehydrogenase - Methanobacterium| thermoautotrophicum Length = 525 Score = 129 bits (324), Expect = 3e-29 Identities = 109/336 (32%), Positives = 166/336 (49%), Gaps = 3/336 (0%) Frame = +2 Query: 311 TILSVDDILALIGDHCHGVIGQLTEDWGEVLFSALKRAGGTAFSNMAVGYNNVDVDAANK 490 T ++ +++L I D V+ T+ EV+ +A + + VG +NVDV AA Sbjct: 30 TTITPEELLDAIKDFDAIVVRSRTKVTREVIEAAPRLK---IIARAGVGVDNVDVKAATD 86 Query: 491 NGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLPHLFVGNLLKGQT 670 GI + N P + T R+I AD+ ++ G W + F+G L G+T Sbjct: 87 RGIMVINAPESTSITVAEHSIGLMLALARKIAIADRSVKEGK---WEKNRFMGIELNGKT 143 Query: 671 VGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRA 850 +G+IG GRIGS + + F M+++ +D Y S +A E VT Sbjct: 144 LGIIGMGRIGSQVV-VRTKAFGMDIMVYDPYISK-------------EAAEEMGVT---V 186 Query: 851 SSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLK 1030 + +E +LRE+D++++H L T HLI+ + +MK A +VN +RG +IDE AL LK Sbjct: 187 TDLETLLRESDIVTIHVPLTPETRHLISEDEFKLMKDTAFIVNCARGGIIDEDALYRALK 246 Query: 1031 ANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHI-ASASKWTREGMATLAALNVLGKIKG 1207 + LDVFE+EP L E++N V+ PHI AS S+ R+ AA+ V +IK Sbjct: 247 DGEIAGAALDVFEEEPPEGSPLLELENVVLTPHIGASTSEAQRD-----AAIIVANEIKT 301 Query: 1208 YPVWGNPNAV--EPFLDEEATPPPACPSIVNAKQLG 1309 G P V P +D E T P I A+++G Sbjct: 302 VFQGGAPRNVLNMPVMDSE-TYKSLKPYIELAEKMG 336
>Q9UBQ7:GRHPR_HUMAN Glyoxylate reductase/hydroxypyruvate reductase - Homo sapiens (Human)| Length = 328 Score = 125 bits (313), Expect = 7e-28 Identities = 99/334 (29%), Positives = 155/334 (46%), Gaps = 1/334 (0%) Frame = +2 Query: 218 RVVSTKSMPGTRWIKLLTDNDCRLEICTEKKTILSVDDILALIGDHCHGVIGQLTEDWGE 397 +V T+ +P + L DC +E + I + + + G HG++ L++ + Sbjct: 8 KVFVTRRIPAEGRVALARAADCEVEQWDSDEPIPAKELERGVAG--AHGLLCLLSDHVDK 65 Query: 398 VLFSALKRAGGTAFSNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXR 577 + A A S M+VG +++ +D K GI +G TP VLT+TT R Sbjct: 66 RILDAAG-ANLKVISTMSVGIDHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLLTTCR 124 Query: 578 RIVEADQFMRAGLYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFD 757 R+ EA + ++ G + W P G L TVG+IG GRIG A AR + +Y Sbjct: 125 RLPEAIEEVKNGGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTG 184 Query: 758 LYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINP 937 + R E+ +F+ S E+ ++D I + L T L N Sbjct: 185 --RQPRPEEAAEFQAEFV--------------STPELAAQSDFIVVACSLTPATEGLCNK 228 Query: 938 ERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEPY-MKPGLAEMKNA 1114 + MK+ AV +N SRG V+++ L + L + + GLDV EP L +KN Sbjct: 229 DFFQKMKETAVFINISRGDVVNQDDLYQALASGKIAAAGLDVTSPEPLPTNHPLLTLKNC 288 Query: 1115 VVVPHIASASKWTREGMATLAALNVLGKIKGYPV 1216 V++PHI SA+ TR M+ LAA N+L ++G P+ Sbjct: 289 VILPHIGSATHRTRNTMSLLAANNLLAGLRGEPM 322
>O29445:SERA_ARCFU D-3-phosphoglycerate dehydrogenase - Archaeoglobus fulgidus| Length = 527 Score = 122 bits (307), Expect = 3e-27 Identities = 95/319 (29%), Positives = 158/319 (49%), Gaps = 5/319 (1%) Frame = +2 Query: 302 EKKTILSVDDILALIGDHCHGVIGQLTEDWGEVLFSA--LKRAGGTAFSNMAVGYNNVDV 475 E KT +S ++++ + + V+ T+ EV+ +A LK G VG +N+D+ Sbjct: 25 EVKTGMSREELIREVPKYEAIVVRSQTKVDAEVIQAAKNLKIIG-----RAGVGVDNIDI 79 Query: 476 DAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLPHLFVGNL 655 +AA + GI + N PG T +T R+I +AD+ ++ G W F+G Sbjct: 80 NAATQRGIVVVNAPGGNTISTAEHAIALMLAAARKIPQADRSVKEGK---WERKKFMGIE 136 Query: 656 LKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPV 835 L+G+T GVIG GR+G A+ + +MN++ +D + S K EQ Sbjct: 137 LRGKTAGVIGLGRVGFEVAKRC-KALEMNVLAYDPFVS--------------KERAEQ-- 179 Query: 836 TWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVAL 1015 + + +L +DVI++H K T LI + MK ++VNA+RG ++DE AL Sbjct: 180 IGVKLVDFDTLLASSDVITVHVPRTKETIGLIGKGQFEKMKDGVIVVNAARGGIVDEAAL 239 Query: 1016 VEHLKANPMFRVGLDVFEDEPYMKPG-LAEMKNAVVVPHIASASKWTREGMATLAALNVL 1192 E +KA + LDV+E EP L ++ N V PHIA++++ + + + A +++ Sbjct: 240 YEAIKAGKVAAAALDVYEKEPPSPDNPLLKLDNVVTTPHIAASTREAQLNVGMIIAEDIV 299 Query: 1193 GKIKGYPVWGNPN--AVEP 1243 KG PV N ++EP Sbjct: 300 NMAKGLPVRNAVNLPSIEP 318
>O04130:SERA_ARATH D-3-phosphoglycerate dehydrogenase, chloroplast precursor -| Arabidopsis thaliana (Mouse-ear cress) Length = 624 Score = 121 bits (304), Expect = 7e-27 Identities = 115/379 (30%), Positives = 173/379 (45%), Gaps = 8/379 (2%) Frame = +2 Query: 197 WNPS-GKYRVVSTKSM--PGTRWIKLLTDNDCRLEICTE--KKTILSVDDILALIGDHCH 361 +NP+ K R++ T+ + G ++ D DC ++ E KK + D ++ G Sbjct: 76 YNPTLPKPRILVTEKLGEAGVNLLREFGDVDCSYDLSPEDLKKKVAESDALIVRSGT--- 132 Query: 362 GVIGQLTEDWGEVLFSALKRAGGTAFSNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTX 541 ++T + E LK G VG +NVD+ AA ++G + N P T Sbjct: 133 ----KVTREVFEAAKGRLKVVG-----RAGVGIDNVDLQAATEHGCLVVNAPTANTVAAA 183 Query: 542 XXXXXXXXXXXRRIVEADQFMRAGLYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMM 721 R + +AD ++AG W +VG L G+T+ V+G G++G+ AR Sbjct: 184 EHGIALLASMARNVAQADASIKAGK---WERSKYVGVSLVGKTLAVMGFGKVGTEVARRA 240 Query: 722 IEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLHP 901 +G M +I D Y A +A G V S ++ + AD +SLH Sbjct: 241 -KGLGMTVISHDPY----------APADRARALGVDLV------SFDQAISTADFVSLHM 283 Query: 902 VLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEPY 1081 L T + N E + MKK L+N +RG VIDE ALV L A + + LDVF +EP Sbjct: 284 PLTPATKKVFNDETFSKMKKGVRLINVARGGVIDEDALVRALDAGIVAQAALDVFCEEPP 343 Query: 1082 MKPG-LAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKGYPVWGNPNA--VEPFLD 1252 K L + +N V PH+ +++K +EG+A A V G +KG NA V P + Sbjct: 344 SKDSRLIQHENVTVTPHLGASTKEAQEGVAIEIAEAVAGALKGELSATAVNAPMVAPEVL 403 Query: 1253 EEATPPPACPSIVNAKQLG 1309 E T P IV A++LG Sbjct: 404 SELT-----PYIVLAEKLG 417
>Q91Z53:GRHPR_MOUSE Glyoxylate reductase/hydroxypyruvate reductase - Mus musculus (Mouse)| Length = 328 Score = 120 bits (302), Expect = 1e-26 Identities = 102/343 (29%), Positives = 153/343 (44%), Gaps = 8/343 (2%) Frame = +2 Query: 203 PSGKYRVVSTKSMPGTRWIKLLTDNDCRLEICTEKKTILSVDDILALIGDHCHGVIGQLT 382 P+ +V T +P L DC +E I D ++G HG++ +L+ Sbjct: 3 PARLMKVFVTGPLPAEGRAALAQAADCEVEQWNSDDPIPRKDLEQGVVG--AHGLLCRLS 60 Query: 383 EDWGEVLFSALKRAGGTAFSNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXX 562 + + L A A S ++VG +++ +D K GI +G TPGVLT+ T Sbjct: 61 DRVDKKLLDAAG-ANLRVISTLSVGVDHLALDEIKKRGIRVGYTPGVLTDATAELAVSLL 119 Query: 563 XXXXRRIVEADQFMRAGLYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMN 742 RR+ EA + ++ G + W P G L TVG++G GRIG A AR Sbjct: 120 LTTCRRLPEAIEEVKNGGWSSWSPLWMCGYGLSQSTVGIVGLGRIGQAIAR--------- 170 Query: 743 LIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEE------VLREADVISLHPV 904 RL+ F Q G QP + A E + E+D I + Sbjct: 171 ----------RLKPFGV---QRFLYTGRQPRPQEAAEFQAEFVPIAQLAAESDFIVVSCS 217 Query: 905 LDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEPYM 1084 L T L + + MK A+ +N SRG V+++ L + L + + GLDV EP + Sbjct: 218 LTPDTMGLCSKDFFQKMKNTAIFINISRGDVVNQEDLYQALASGQIAAAGLDVTTPEP-L 276 Query: 1085 KPG--LAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKG 1207 P L +KN V++PHI SA+ TR M+ LAA N+L ++G Sbjct: 277 PPSHPLLTLKNCVILPHIGSATYKTRNTMSLLAANNLLAGLRG 319
>P35136:SERA_BACSU D-3-phosphoglycerate dehydrogenase - Bacillus subtilis| Length = 525 Score = 119 bits (299), Expect = 3e-26 Identities = 85/274 (31%), Positives = 131/274 (47%) Frame = +2 Query: 452 VGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWL 631 VG +N+D+D A K+G+ + N P T +T R I +A+ +++ W Sbjct: 71 VGVDNIDIDEATKHGVIVINAPNGNTISTAEHTFAMISSLMRHIPQANISVKSR---EWN 127 Query: 632 PHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFL 811 +VG+ L G+T+G++G GRIGS A+ F M + FD + + K + Sbjct: 128 RTAYVGSELYGKTLGIVGLGRIGSEIAQRR-GAFGMTVHVFDPFLTEERAKKIGV----- 181 Query: 812 KANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRG 991 + + EEVL AD+I++H L K T L+N E +A KK L+N +RG Sbjct: 182 -----------NSRTFEEVLESADIITVHTPLTKETKGLLNKETIAKTKKGVRLINCARG 230 Query: 992 PVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMAT 1171 +IDE AL+E L+ + LDVFE EP + L + + PH+ +++K + +A Sbjct: 231 GIIDEAALLEALENGHVAGAALDVFEVEPPVDNKLVDHPLVIATPHLGASTKEAQLNVAA 290 Query: 1172 LAALNVLGKIKGYPVWGNPNAVEPFLDEEATPPP 1273 + VL KG PV N DE A P Sbjct: 291 QVSEEVLQFAKGLPVMSAINLPAMTKDEFAKIKP 324
>Q58424:SERA_METJA D-3-phosphoglycerate dehydrogenase - Methanococcus jannaschii| Length = 524 Score = 118 bits (295), Expect = 8e-26 Identities = 88/302 (29%), Positives = 143/302 (47%) Frame = +2 Query: 302 EKKTILSVDDILALIGDHCHGVIGQLTEDWGEVLFSALKRAGGTAFSNMAVGYNNVDVDA 481 E T L+ +++L I D V+ T+ +V+ A K VG +N+DV+A Sbjct: 25 EVATGLTKEELLEKIKDADVLVVRSGTKVTRDVIEKAEKLK---VIGRAGVGVDNIDVEA 81 Query: 482 ANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLPHLFVGNLLK 661 A + GI + N P + + R I +A ++ G +D F G L Sbjct: 82 ATEKGIIVVNAPDASSISVAELTMGLMLAAARNIPQATASLKRGEWDR---KRFKGIELY 138 Query: 662 GQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTW 841 G+T+GVIG GRIG + + F MN+I +D Y + + + Sbjct: 139 GKTLGVIGLGRIGQQVVKRA-KAFGMNIIGYDPYIPKEVAESMGV--------------- 182 Query: 842 KRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVE 1021 + + E+ + AD I+LH L T H+I E++A+MKK A++VN +RG +IDE AL E Sbjct: 183 ELVDDINELCKRADFITLHVPLTPKTRHIIGREQIALMKKNAIIVNCARGGLIDEKALYE 242 Query: 1022 HLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKI 1201 LK + LDVFE+EP L + N + PH ++++ ++ T+ A + + Sbjct: 243 ALKEGKIRAAALDVFEEEPPKDNPLLTLDNVIGTPHQGASTEEAQKAAGTIVAEQIKKVL 302 Query: 1202 KG 1207 +G Sbjct: 303 RG 304
>P36234:DHGY_HYPME Glycerate dehydrogenase - Hyphomicrobium methylovorum| Length = 322 Score = 117 bits (293), Expect = 1e-25 Identities = 80/299 (26%), Positives = 138/299 (46%), Gaps = 1/299 (0%) Frame = +2 Query: 275 NDCRLEICTEKKTILSVDDILALIGDHCHG-VIGQLTEDWGEVLFSALKRAGGTAFSNMA 451 +D ++ I +T SVD +L + + C VI ++ E+ S + Sbjct: 31 DDPKITIDEMIETAKSVDALLITLNEKCRKEVIDRIPENI-------------KCISTYS 77 Query: 452 VGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWL 631 +G++++D+DA GI +GN P +T T RR E ++ +R + GW Sbjct: 78 IGFDHIDLDACKARGIKVGNAPHGVTVATAEIAMLLLLGSARRAGEGEKMIRTRSWPGWE 137 Query: 632 PHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFL 811 P VG L +T+G+ G G IG A A+ +GF M++ YFD ++++ Sbjct: 138 PLELVGEKLDNKTLGIYGFGSIGQALAK-RAQGFDMDIDYFDTHRAS------------- 183 Query: 812 KANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRG 991 ++ E S++ +L + SL+ T + N + + + A++VN +RG Sbjct: 184 -SSDEASYQATFHDSLDSLLSVSQFFSLNAPSTPETRYFFNKATIKSLPQGAIVVNTARG 242 Query: 992 PVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA 1168 ++D +V L+A + G DVF EP + G ++ N + PHI SA+ RE MA Sbjct: 243 DLVDNELVVAALEAGRLAYAGFDVFAGEPNINEGYYDLPNTFLFPHIGSAATQAREDMA 301
>O33116:SERA_MYCLE D-3-phosphoglycerate dehydrogenase - Mycobacterium leprae| Length = 528 Score = 112 bits (280), Expect = 4e-24 Identities = 85/272 (31%), Positives = 124/272 (45%) Frame = +2 Query: 452 VGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWL 631 VG +NVDVDAA G+ + N P + R+I EAD +RA + W Sbjct: 74 VGLDNVDVDAATARGVLVVNAPTSNIHSAAEHALALLLAASRQIAEADASLRAHI---WK 130 Query: 632 PHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFL 811 F G + G+TVGV+G GRIG A I F ++I +D Y Sbjct: 131 RSSFSGTEIFGKTVGVVGLGRIGQLVAAR-IAAFGAHVIAYDPYV--------------- 174 Query: 812 KANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRG 991 A S +++L AD IS+H T LI+ E LA K ++VNA+RG Sbjct: 175 -APARAAQLGIELMSFDDLLARADFISVHLPKTPETAGLIDKEALAKTKPGVIIVNAARG 233 Query: 992 PVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMAT 1171 ++DEVAL + +++ + GLDVF EP L E+ VV PH+ +++ ++ T Sbjct: 234 GLVDEVALADAVRSGHVRAAGLDVFATEPCTDSPLFELSQVVVTPHLGASTAEAQDRAGT 293 Query: 1172 LAALNVLGKIKGYPVWGNPNAVEPFLDEEATP 1267 A +V + G V N ++EE P Sbjct: 294 DVAESVRLALAGEFVPDAVNVDGGVVNEEVAP 325
>O69054:PTXD_PSEST Phosphonate dehydrogenase - Pseudomonas stutzeri (Pseudomonas| perfectomarina) Length = 336 Score = 107 bits (267), Expect = 1e-22 Identities = 79/259 (30%), Positives = 120/259 (46%), Gaps = 8/259 (3%) Frame = +2 Query: 455 GYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLP 634 G++N DVDA G+ + P +LT T R + AD F+R+G + GW P Sbjct: 77 GFDNFDVDACTARGVWLTFVPDLLTVPTAELAIGLAVGLGRHLRAADAFVRSGEFQGWQP 136 Query: 635 HLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLK 814 F G L TVG++G G IG A A + +G+ L Y + + L Sbjct: 137 Q-FYGTGLDNATVGILGMGAIGLAMADRL-QGWGATLQYHE--------------AKALD 180 Query: 815 ANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGP 994 EQ + ++ + E+ +D I L L+ T HL+N E LA+++ A+LVN RG Sbjct: 181 TQTEQRLGLRQVAC-SELFASSDFILLALPLNADTQHLVNAELLALVRPGALLVNPCRGS 239 Query: 995 VIDEVALVEHLKANPMFRVGLDVFEDEPYMK--------PGLAEMKNAVVVPHIASASKW 1150 V+DE A++ L+ + DVFE E + + P L N + PHI SA + Sbjct: 240 VVDEAAVLAALERGQLGGYAADVFEMEDWARADRPRLIDPALLAHPNTLFTPHIGSAVRA 299 Query: 1151 TREGMATLAALNVLGKIKG 1207 R + AA N++ + G Sbjct: 300 VRLEIERCAAQNIIQVLAG 318
>P53839:YN14_YEAST Putative 2-hydroxyacid dehydrogenase YNL274C - Saccharomyces| cerevisiae (Baker's yeast) Length = 350 Score = 105 bits (263), Expect = 4e-22 Identities = 83/288 (28%), Positives = 130/288 (45%), Gaps = 3/288 (1%) Frame = +2 Query: 434 AFSNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAG 613 A + GY+ +DV+ K I + N P +++ T R ++ + G Sbjct: 85 AVCHTGAGYDQIDVEPFKKRHIQVANVPDLVSNATADTHVFLLLGALRNFGIGNRRLIEG 144 Query: 614 LYDGWLPHLF--VGNLLKGQTVGVIGAGRIGSAYA-RMMIEGFKMNLIYFDLYQSTRLEK 784 + P G +G+TVG++G GRIG R+ GF+ N IY + +Q E+ Sbjct: 145 NWPEAGPACGSPFGYDPEGKTVGILGLGRIGRCILERLKPFGFE-NFIYHNRHQLPSEEE 203 Query: 785 FVTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKE 964 Y F EE L+ +D++S++ L+ T+HLIN E + MK Sbjct: 204 HGCEYVGF-----------------EEFLKRSDIVSVNVPLNHNTHHLINAETIEKMKDG 246 Query: 965 AVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASAS 1144 V+VN +RG VIDE A+ + L++ + GLDVFE EP + L M + +PH+ + S Sbjct: 247 VVIVNTARGAVIDEQAMTDALRSGKIRSAGLDVFEYEPKISKELLSMSQVLGLPHMGTHS 306 Query: 1145 KWTREGMATLAALNVLGKIKGYPVWGNPNAVEPFLDEEATPPPACPSI 1288 TR+ M L N K + G + P L E P + P + Sbjct: 307 VETRKKMEELVVENA----KNVILTGKVLTIVPELQNEDWPNESKPLV 350
>O43175:SERA_HUMAN D-3-phosphoglycerate dehydrogenase - Homo sapiens (Human)| Length = 533 Score = 105 bits (263), Expect = 4e-22 Identities = 86/311 (27%), Positives = 144/311 (46%), Gaps = 1/311 (0%) Frame = +2 Query: 305 KKTILSVDDILALIGDHCHG-VIGQLTEDWGEVLFSALKRAGGTAFSNMAVGYNNVDVDA 481 +K LS ++++A + D C G ++ T+ +V+ +A K G +NVD++A Sbjct: 32 EKQNLSKEELIAELQD-CEGLIVRSATKVTADVINAAEKLQ---VVGRAGTGVDNVDLEA 87 Query: 482 ANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLPHLFVGNLLK 661 A + GI + NTP + + R+I +A M+ G W F+G L Sbjct: 88 ATRKGILVMNTPNGNSLSAAELTCGMIMCLARQIPQATASMKDGK---WERKKFMGTELN 144 Query: 662 GQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTW 841 G+T+G++G GRIG A M + F M I +D S + + G Q + Sbjct: 145 GKTLGILGLGRIGREVATRM-QSFGMKTIGYDPIISPEVSA----------SFGVQQLP- 192 Query: 842 KRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVE 1021 +EE+ D I++H L +T L+N A KK +VN +RG ++DE AL+ Sbjct: 193 -----LEEIWPLCDFITVHTPLLPSTTGLLNDNTFAQCKKGVRVVNCARGGIVDEGALLR 247 Query: 1022 HLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKI 1201 L++ LDVF +EP L + +N + PH+ +++K + A+ + + Sbjct: 248 ALQSGQCAGAALDVFTEEPPRDRALVDHENVISCPHLGASTKEAQSRCGEEIAVQFVDMV 307 Query: 1202 KGYPVWGNPNA 1234 KG + G NA Sbjct: 308 KGKSLTGVVNA 318
>Q61753:SERA_MOUSE D-3-phosphoglycerate dehydrogenase - Mus musculus (Mouse)| Length = 533 Score = 105 bits (262), Expect = 5e-22 Identities = 84/311 (27%), Positives = 145/311 (46%), Gaps = 1/311 (0%) Frame = +2 Query: 305 KKTILSVDDILALIGDHCHG-VIGQLTEDWGEVLFSALKRAGGTAFSNMAVGYNNVDVDA 481 +K LS ++++A + D C G ++ T+ +V+ +A K G +NVD++A Sbjct: 32 EKQNLSKEELIAELQD-CEGLIVRSATKVTADVINAAEKLQ---VVGRAGTGVDNVDLEA 87 Query: 482 ANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLPHLFVGNLLK 661 A + GI + NTP + + R+I +A M+ G +D F+G L Sbjct: 88 ATRKGILVMNTPNGNSLSAAELTCGMIMCLARQIPQATASMKDGKWDR---KKFMGTELN 144 Query: 662 GQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTW 841 G+T+G++G GRIG A M + F M + +D S + ++G Sbjct: 145 GKTLGILGLGRIGREVATRM-QSFGMKTVGYDPIISPEV---AASFGV------------ 188 Query: 842 KRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVE 1021 + +EE+ D I++H L +T L+N A KK +VN +RG ++DE AL+ Sbjct: 189 -QQLPLEEIWPLCDFITVHTPLLPSTTGLLNDSTFAQCKKGVRVVNCARGGIVDEGALLR 247 Query: 1022 HLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKI 1201 L++ LDVF +EP L + +N + PH+ +++K + A+ + + Sbjct: 248 ALQSGQCAGAALDVFTEEPPRDRALVDHENVISCPHLGASTKEAQSRCGEEIAVQFVDMV 307 Query: 1202 KGYPVWGNPNA 1234 KG + G NA Sbjct: 308 KGKSLTGVVNA 318
>Q9W758:CTBP2_XENLA C-terminal-binding protein 2 - Xenopus laevis (African clawed frog)| Length = 437 Score = 105 bits (262), Expect = 5e-22 Identities = 87/313 (27%), Positives = 145/313 (46%), Gaps = 14/313 (4%) Frame = +2 Query: 239 MPGTRWIKLLTDNDCRLEICTEKKTILSVDDILALIGDHCHGVIGQLTEDWGEVLFSA-- 412 MP + LL DC +E+ K + +V A H + L+E G +++ Sbjct: 27 MPVRPLVALLDGRDCTIEMPI-LKDVATVAFCDAQSTQEIHEKV--LSEAVGALMYHTIT 83 Query: 413 LKRAGGTAFSNMAV------GYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXX 574 L R F + + GY+N+D+ +A + GIA+ N P E T Sbjct: 84 LSREDLEKFKALRIIIKIGSGYDNIDIKSAAELGIAVCNIPSASVEETADSTLCHILNLY 143 Query: 575 RRIVEADQFMRAGLYDGWLPHL--FVGNL--LKGQTVGVIGAGRIGSAYARMMIEGFKMN 742 RR+ Q MR G + + G ++G+T+G+IG GRIG A A + + F Sbjct: 144 RRVTWLHQAMREGNRPASVEQIREVAGGAARIRGETLGIIGLGRIGQAVA-LRAKAFNFT 202 Query: 743 LIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTY 922 +I++D Y + +E+ + +R ++++E+L +D I+LH L++ + Sbjct: 203 VIFYDPYLADGVERSLGL---------------QRMATLQELLMHSDCITLHCNLNEHNH 247 Query: 923 HLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEP--YMKPGL 1096 HLIN + M++ LVN +RG ++DE AL + LK + LDV E EP + + L Sbjct: 248 HLINDFTIKQMRQGCFLVNTARGGLVDEKALAQALKDGRIRGAALDVHESEPFSFSQGPL 307 Query: 1097 AEMKNAVVVPHIA 1135 + N + PH A Sbjct: 308 KDAPNLICTPHTA 320
>O08651:SERA_RAT D-3-phosphoglycerate dehydrogenase - Rattus norvegicus (Rat)| Length = 533 Score = 105 bits (261), Expect = 7e-22 Identities = 83/311 (26%), Positives = 145/311 (46%), Gaps = 1/311 (0%) Frame = +2 Query: 305 KKTILSVDDILALIGDHCHG-VIGQLTEDWGEVLFSALKRAGGTAFSNMAVGYNNVDVDA 481 +K LS ++++A + D C G ++ T+ +V+ +A K G +NVD++A Sbjct: 32 EKQNLSKEELIAELQD-CEGLIVRSATKVTADVINAAEKLQ---VVGRAGTGVDNVDLEA 87 Query: 482 ANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLPHLFVGNLLK 661 A + G+ + NTP + + R+I +A M+ G +D F+G L Sbjct: 88 ATRKGVLVMNTPNGNSLSAAELTCGMLMCLARQIPQATASMKDGKWDR---KKFMGTELN 144 Query: 662 GQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTW 841 G+T+G++G GRIG A M + F M + +D S + ++G Sbjct: 145 GKTLGILGLGRIGREVAARM-QAFGMKTVGYDPIISPEV---AASFGV------------ 188 Query: 842 KRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVE 1021 + +EE+ D I++H L +T L+N A KK +VN +RG ++DE AL+ Sbjct: 189 -QQLPLEEIWPLCDFITVHTPLLPSTTGLLNDSTFAQCKKGVRVVNCARGGIVDEGALLR 247 Query: 1022 HLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKI 1201 L++ LDVF +EP L + +N + PH+ +++K + A+ + + Sbjct: 248 ALQSGQCAGAALDVFTEEPPRDRALVDHENVISCPHLGASTKEAQSRCGEEIAVQFVDMV 307 Query: 1202 KGYPVWGNPNA 1234 KG + G NA Sbjct: 308 KGKSLTGVVNA 318
>Q60HD7:SERA_MACFA D-3-phosphoglycerate dehydrogenase - Macaca fascicularis (Crab eating| macaque) (Cynomolgus monkey) Length = 533 Score = 105 bits (261), Expect = 7e-22 Identities = 85/311 (27%), Positives = 144/311 (46%), Gaps = 1/311 (0%) Frame = +2 Query: 305 KKTILSVDDILALIGDHCHG-VIGQLTEDWGEVLFSALKRAGGTAFSNMAVGYNNVDVDA 481 +K LS ++++A + D C G ++ T+ +V+ +A K G +NVD++A Sbjct: 32 EKQNLSKEELIAELQD-CEGLIVRSATKVTADVINAAEKLQ---VVGRAGTGVDNVDLEA 87 Query: 482 ANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLPHLFVGNLLK 661 A + G+ + NTP + + R+I +A M+ G W F+G L Sbjct: 88 ATRKGVLVMNTPNGNSLSAAELTCGMIMCLARQIPQATASMKDGK---WERKKFMGTELN 144 Query: 662 GQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTW 841 G+T+G++G GRIG A M + F M I +D S + + G Q + Sbjct: 145 GKTLGILGLGRIGREVATRM-QSFGMKTIGYDPIISPEVSA----------SFGVQQLP- 192 Query: 842 KRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVE 1021 +EE+ D I++H L +T L+N A KK +VN +RG ++DE AL+ Sbjct: 193 -----LEEIWPLCDFITVHTPLLPSTTGLLNDNTFAQCKKGVRVVNCARGGIVDEGALLR 247 Query: 1022 HLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKI 1201 L++ LDVF +EP L + +N + PH+ +++K + A+ + + Sbjct: 248 ALQSGQCAGAALDVFTEEPPRDRALVDHENVISCPHLGASTKEAQSRCGEEIAVQFVDMV 307 Query: 1202 KGYPVWGNPNA 1234 KG + G NA Sbjct: 308 KGKSLAGVVNA 318
>P56545:CTBP2_HUMAN C-terminal-binding protein 2 - Homo sapiens (Human)| Length = 445 Score = 105 bits (261), Expect = 7e-22 Identities = 91/315 (28%), Positives = 145/315 (46%), Gaps = 26/315 (8%) Frame = +2 Query: 455 GYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLP 634 GY+NVD+ AA + GIA+ N P E T RR Q +R G + Sbjct: 107 GYDNVDIKAAGELGIAVCNIPSAAVEETADSTICHILNLYRRNTWLYQALREGTRVQSVE 166 Query: 635 HLFV----GNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYG 802 + ++G+T+G+IG GR G A A + + F ++I++D Y +E+ + Sbjct: 167 QIREVASGAARIRGETLGLIGFGRTGQAVA-VRAKAFGFSVIFYDPYLQDGIERSLGV-- 223 Query: 803 QFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNA 982 +R +++++L ++D +SLH L++ +HLIN + M++ A LVNA Sbjct: 224 -------------QRVYTLQDLLYQSDCVSLHCNLNEHNHHLINDFTIKQMRQGAFLVNA 270 Query: 983 SRGPVIDEVALVEHLKANPMFRVGLDVFEDEP--YMKPGLAEMKNAVVVPHIA----SAS 1144 +RG ++DE AL + LK + LDV E EP + + L + N + PH A AS Sbjct: 271 ARGGLVDEKALAQALKEGRIRGAALDVHESEPFSFAQGPLKDAPNLICTPHTAWYSEQAS 330 Query: 1145 KWTREGMATLAALNVLGKI---------KGYPVWGNPNAVEPFLDEEATPPPA------- 1276 RE AT + G+I K + V P +V +D++A P Sbjct: 331 LEMREAAATEIRRAITGRIPESLRNCVNKEFFVTSAPWSV---IDQQAIHPELNGATYRY 387 Query: 1277 CPSIVNAKQLGLPSS 1321 P IV GLP++ Sbjct: 388 PPGIVGVAPGGLPAA 402
>O94574:YGDH_SCHPO Putative 2-hydroxyacid dehydrogenase C1773.17c - Schizosaccharomyces| pombe (Fission yeast) Length = 340 Score = 104 bits (260), Expect = 9e-22 Identities = 73/239 (30%), Positives = 114/239 (47%) Frame = +2 Query: 437 FSNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGL 616 F A GYNNVDVD A +NG+ + NTP TE T R EA+Q +R G Sbjct: 87 FVTGAAGYNNVDVDWATRNGVYVANTPNGPTEGTANMNLMLFMCTLRGAREAEQSLRLGK 146 Query: 617 YDGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTA 796 W +L + + G+ VG+IG G IG ++A+ ++ ++Y + RLE Sbjct: 147 ---WRQNLSLTDDPYGKRVGIIGMGAIGKSFAQKILP-LGCEIVY---HNRNRLEA---- 195 Query: 797 YGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLV 976 E+ S +E+L +DVIS++ L T+ LI+ + MK ++ Sbjct: 196 --------EEEKRLGASFVSFDELLSSSDVISINCPLTPATHDLISTKEFEKMKDGVYII 247 Query: 977 NASRGPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWT 1153 N +RG +I+E A ++ +K+ + R GLDVF +EP E + PH + +T Sbjct: 248 NTARGAIINEDAFIKAIKSGKVARAGLDVFLNEPTPNKFWLECDKVTIQPHCGVYTNFT 306
>O14075:YEAA_SCHPO Putative 2-hydroxyacid dehydrogenase UNK4.10 - Schizosaccharomyces| pombe (Fission yeast) Length = 334 Score = 104 bits (260), Expect = 9e-22 Identities = 71/253 (28%), Positives = 120/253 (47%), Gaps = 4/253 (1%) Frame = +2 Query: 443 NMAVGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYD 622 ++ GY VDV A GI + + P + + T R + G+++ Sbjct: 86 HLGAGYETVDVAACTARGIQVSHVPKAVDDATADVGIFLMLGALRGFNQ-------GIFE 138 Query: 623 ----GWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFV 790 W + + +G+T+G++G G IG A+ F M ++Y + T L + Sbjct: 139 LHKNNWNANCKPSHDPEGKTLGILGLGGIGKTMAKRA-RAFDMKIVY---HNRTPLPEEE 194 Query: 791 TAYGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAV 970 +F+ S +++L ++DV+SL+ L+ T H+I MK+ V Sbjct: 195 AEGAEFV--------------SFDDLLAKSDVLSLNLPLNAHTRHIIGKPEFQKMKRGIV 240 Query: 971 LVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKW 1150 +VN +RG V+DE ALVE L ++ GLDVFE+EP + PGL E + +++PH+ + S Sbjct: 241 IVNTARGAVMDEAALVEALDEGIVYSAGLDVFEEEPKIHPGLLENEKVILLPHLGTNSLE 300 Query: 1151 TREGMATLAALNV 1189 T+ M +NV Sbjct: 301 TQYKMECAVLMNV 313
>P0A544:SERA_MYCTU D-3-phosphoglycerate dehydrogenase - Mycobacterium tuberculosis| Length = 528 Score = 104 bits (260), Expect = 9e-22 Identities = 92/314 (29%), Positives = 137/314 (43%) Frame = +2 Query: 326 DDILALIGDHCHGVIGQLTEDWGEVLFSALKRAGGTAFSNMAVGYNNVDVDAANKNGIAI 505 D +LA + + ++ T EVL +A K + VG +NVDVDAA G+ + Sbjct: 35 DKLLAAVPEADALLVRSATTVDAEVLAAAPKLK---IVARAGVGLDNVDVDAATARGVLV 91 Query: 506 GNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLPHLFVGNLLKGQTVGVIG 685 N P + R+I AD +R W F G + G+TVGV+G Sbjct: 92 VNAPTSNIHSAAEHALALLLAASRQIPAADASLREHT---WKRSSFSGTEIFGKTVGVVG 148 Query: 686 AGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEE 865 GRIG A+ I F ++ +D Y S A Q S+++ Sbjct: 149 LGRIGQLVAQR-IAAFGAYVVAYDPYVSP--------------ARAAQ--LGIELLSLDD 191 Query: 866 VLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMF 1045 +L AD IS+H T LI+ E LA K ++VNA+RG ++DE AL + + + Sbjct: 192 LLARADFISVHLPKTPETAGLIDKEALAKTKPGVIIVNAARGGLVDEAALADAITGGHVR 251 Query: 1046 RVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKGYPVWGN 1225 GLDVF EP L E+ VV PH+ +++ ++ T A +V + G V Sbjct: 252 AAGLDVFATEPCTDSPLFELAQVVVTPHLGASTAEAQDRAGTDVAESVRLALAGEFVPDA 311 Query: 1226 PNAVEPFLDEEATP 1267 N ++EE P Sbjct: 312 VNVGGGVVNEEVAP 325
>P0A545:SERA_MYCBO D-3-phosphoglycerate dehydrogenase - Mycobacterium bovis| Length = 528 Score = 104 bits (260), Expect = 9e-22 Identities = 92/314 (29%), Positives = 137/314 (43%) Frame = +2 Query: 326 DDILALIGDHCHGVIGQLTEDWGEVLFSALKRAGGTAFSNMAVGYNNVDVDAANKNGIAI 505 D +LA + + ++ T EVL +A K + VG +NVDVDAA G+ + Sbjct: 35 DKLLAAVPEADALLVRSATTVDAEVLAAAPKLK---IVARAGVGLDNVDVDAATARGVLV 91 Query: 506 GNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLPHLFVGNLLKGQTVGVIG 685 N P + R+I AD +R W F G + G+TVGV+G Sbjct: 92 VNAPTSNIHSAAEHALALLLAASRQIPAADASLREHT---WKRSSFSGTEIFGKTVGVVG 148 Query: 686 AGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEE 865 GRIG A+ I F ++ +D Y S A Q S+++ Sbjct: 149 LGRIGQLVAQR-IAAFGAYVVAYDPYVSP--------------ARAAQ--LGIELLSLDD 191 Query: 866 VLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMF 1045 +L AD IS+H T LI+ E LA K ++VNA+RG ++DE AL + + + Sbjct: 192 LLARADFISVHLPKTPETAGLIDKEALAKTKPGVIIVNAARGGLVDEAALADAITGGHVR 251 Query: 1046 RVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKGYPVWGN 1225 GLDVF EP L E+ VV PH+ +++ ++ T A +V + G V Sbjct: 252 AAGLDVFATEPCTDSPLFELAQVVVTPHLGASTAEAQDRAGTDVAESVRLALAGEFVPDA 311 Query: 1226 PNAVEPFLDEEATP 1267 N ++EE P Sbjct: 312 VNVGGGVVNEEVAP 325
>P56546:CTBP2_MOUSE C-terminal-binding protein 2 - Mus musculus (Mouse)| Length = 445 Score = 104 bits (260), Expect = 9e-22 Identities = 78/259 (30%), Positives = 125/259 (48%), Gaps = 10/259 (3%) Frame = +2 Query: 455 GYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLP 634 GY+NVD+ AA + GIA+ N P E T RR Q +R G + Sbjct: 107 GYDNVDIKAAGELGIAVCNIPSAAVEETADSTVCHILNLYRRNTWLYQALREGTRVQSVE 166 Query: 635 HLFV----GNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYG 802 + ++G+T+G+IG GR G A A + + F ++I++D Y +E+ + Sbjct: 167 QIREVASGAARIRGETLGLIGFGRTGQAVA-VRAKAFGFSVIFYDPYLQDGIERSLGV-- 223 Query: 803 QFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNA 982 +R +++++L ++D +SLH L++ +HLIN + M++ A LVNA Sbjct: 224 -------------QRVYTLQDLLYQSDCVSLHCNLNEHNHHLINDFTIKQMRQGAFLVNA 270 Query: 983 SRGPVIDEVALVEHLKANPMFRVGLDVFEDEP--YMKPGLAEMKNAVVVPHIA----SAS 1144 +RG ++DE AL + LK + LDV E EP + + L + N + PH A AS Sbjct: 271 ARGGLVDEKALAQALKEGRIRGAALDVHESEPFSFAQGPLKDAPNLICTPHTAWYSEQAS 330 Query: 1145 KWTREGMATLAALNVLGKI 1201 RE AT + G+I Sbjct: 331 LEMREAAATEIRRAITGRI 349
>Q0VCQ1:CTBP2_BOVIN C-terminal-binding protein 2 - Bos taurus (Bovine)| Length = 445 Score = 104 bits (259), Expect = 1e-21 Identities = 78/259 (30%), Positives = 126/259 (48%), Gaps = 10/259 (3%) Frame = +2 Query: 455 GYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLP 634 GY+NVD+ AA + GIA+ N P E T RR Q +R G + Sbjct: 107 GYDNVDIKAAGELGIAVCNIPSAAVEETADSTICHILNLYRRNTWLYQALREGTRVQSVE 166 Query: 635 HLFV----GNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYG 802 + ++G+T+G+IG GR G A A + + F +++++D Y Sbjct: 167 QIREVASGAARIRGETLGLIGFGRTGQAVA-VRAKAFGFSVLFYDPY------------- 212 Query: 803 QFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNA 982 L+ E+ + +R +++++L ++D +SLH L++ +HLIN + M++ A LVNA Sbjct: 213 --LQDGTERSLGVQRVYTLQDLLYQSDCVSLHCNLNEHNHHLINDFTIKQMRQGAFLVNA 270 Query: 983 SRGPVIDEVALVEHLKANPMFRVGLDVFEDEP--YMKPGLAEMKNAVVVPHIA----SAS 1144 +RG ++DE AL + LK + LDV E EP + + L + N + PH A AS Sbjct: 271 ARGGLVDEKALAQALKEGRIRGAALDVHESEPFSFAQGPLKDAPNLICTPHTAWYSEQAS 330 Query: 1145 KWTREGMATLAALNVLGKI 1201 RE AT + G+I Sbjct: 331 LEMREAAATEIRRAITGRI 349
>Q9Z2F5:CTBP1_RAT C-terminal-binding protein 1 - Rattus norvegicus (Rat)| Length = 430 Score = 104 bits (259), Expect = 1e-21 Identities = 76/257 (29%), Positives = 124/257 (48%), Gaps = 6/257 (2%) Frame = +2 Query: 455 GYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLP 634 G++N+D+ +A GIA+ N P E T RR Q +R G + Sbjct: 90 GFDNIDIKSAGDLGIAVCNVPAASVEETADSTLCHILNLYRRTTWLHQALREGTRVQSVE 149 Query: 635 HLFV----GNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYG 802 + ++G+T+G+IG GR+G A A + + F N++++D Y S +E+ Sbjct: 150 QIREVASGAARIRGETLGIIGLGRVGQAVA-LRAKAFGFNVLFYDPYLSDGIER------ 202 Query: 803 QFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNA 982 A G Q R S+++++L +D ++LH L++ +HLIN + M++ A LVN Sbjct: 203 ----ALGLQ-----RVSTLQDLLFHSDCVTLHCGLNEHNHHLINDFTVKQMRQGAFLVNT 253 Query: 983 SRGPVIDEVALVEHLKANPMFRVGLDVFEDEP--YMKPGLAEMKNAVVVPHIASASKWTR 1156 +RG ++DE AL + LK + LDV E EP + + L + N + PH A S+ Sbjct: 254 ARGGLVDEKALAQALKEGRIRGAALDVHESEPFSFSQGPLKDAPNLICTPHAAWYSEQAS 313 Query: 1157 EGMATLAALNVLGKIKG 1207 M AA + I G Sbjct: 314 IEMREEAAREIRRAITG 330
>O88712:CTBP1_MOUSE C-terminal-binding protein 1 - Mus musculus (Mouse)| Length = 441 Score = 104 bits (259), Expect = 1e-21 Identities = 76/257 (29%), Positives = 124/257 (48%), Gaps = 6/257 (2%) Frame = +2 Query: 455 GYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLP 634 G++N+D+ +A GIA+ N P E T RR Q +R G + Sbjct: 101 GFDNIDIKSAGDLGIAVCNVPAASVEETADSTLCHILNLYRRTTWLHQALREGTRVQSVE 160 Query: 635 HLFV----GNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYG 802 + ++G+T+G+IG GR+G A A + + F N++++D Y S +E+ Sbjct: 161 QIREVASGAARIRGETLGIIGLGRVGQAVA-LRAKAFGFNVLFYDPYLSDGIER------ 213 Query: 803 QFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNA 982 A G Q R S+++++L +D ++LH L++ +HLIN + M++ A LVN Sbjct: 214 ----ALGLQ-----RVSTLQDLLFHSDCVTLHCGLNEHNHHLINDFTVKQMRQGAFLVNT 264 Query: 983 SRGPVIDEVALVEHLKANPMFRVGLDVFEDEP--YMKPGLAEMKNAVVVPHIASASKWTR 1156 +RG ++DE AL + LK + LDV E EP + + L + N + PH A S+ Sbjct: 265 ARGGLVDEKALAQALKEGRIRGAALDVHESEPFSFSQGPLKDAPNLICTPHAAWYSEQAS 324 Query: 1157 EGMATLAALNVLGKIKG 1207 M AA + I G Sbjct: 325 IEMREEAAREIRRAITG 341
>Q13363:CTBP1_HUMAN C-terminal-binding protein 1 - Homo sapiens (Human)| Length = 440 Score = 103 bits (258), Expect = 2e-21 Identities = 76/257 (29%), Positives = 124/257 (48%), Gaps = 6/257 (2%) Frame = +2 Query: 455 GYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLP 634 G++N+D+ +A GIA+ N P E T RR Q +R G + Sbjct: 101 GFDNIDIKSAGDLGIAVCNVPAASVEETADSTLCHILNLYRRATWLHQALREGTRVQSVE 160 Query: 635 HLFV----GNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYG 802 + ++G+T+G+IG GR+G A A + + F N++++D Y S +E+ Sbjct: 161 QIREVASGAARIRGETLGIIGLGRVGQAVA-LRAKAFGFNVLFYDPYLSDGVER------ 213 Query: 803 QFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNA 982 A G Q R S+++++L +D ++LH L++ +HLIN + M++ A LVN Sbjct: 214 ----ALGLQ-----RVSTLQDLLFHSDCVTLHCGLNEHNHHLINDFTVKQMRQGAFLVNT 264 Query: 983 SRGPVIDEVALVEHLKANPMFRVGLDVFEDEP--YMKPGLAEMKNAVVVPHIASASKWTR 1156 +RG ++DE AL + LK + LDV E EP + + L + N + PH A S+ Sbjct: 265 ARGGLVDEKALAQALKEGRIRGAALDVHESEPFSFSQGPLKDAPNLICTPHAAWYSEQAS 324 Query: 1157 EGMATLAALNVLGKIKG 1207 M AA + I G Sbjct: 325 IEMREEAAREIRRAITG 341
>P52643:LDHD_ECOLI D-lactate dehydrogenase - Escherichia coli| Length = 329 Score = 103 bits (257), Expect = 2e-21 Identities = 76/240 (31%), Positives = 108/240 (45%) Frame = +2 Query: 356 CHGVIGQLTEDWGEVLFSALKRAGGTAFSNMAVGYNNVDVDAANKNGIAIGNTPGVLTET 535 C V + +D + LK+ G + G+NNVD+DAA + G+ + P E Sbjct: 45 CEAVCIFVNDDGSRPVLEELKKHGVKYIALRCAGFNNVDLDAAKELGLKVVRVPAYDPEA 104 Query: 536 TXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAYAR 715 RRI A Q R + L L G + G+T GVIG G+IG A R Sbjct: 105 VAEHAIGMMMTLNRRIHRAYQRTRDANFS--LEGL-TGFTMYGKTAGVIGTGKIGVAMLR 161 Query: 716 MMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADVISL 895 ++ +GF M L+ FD Y S + Y + + E+DVISL Sbjct: 162 IL-KGFGMRLLAFDPYPSAAALELGVEY-----------------VDLPTLFSESDVISL 203 Query: 896 HPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDE 1075 H L YHL+N MK ++VN SRG +ID A +E LK + +G+DV+E+E Sbjct: 204 HCPLTPENYHLLNEAAFEQMKNGVMIVNTSRGALIDSQAAIEALKNQKIGSLGMDVYENE 263
>Q9YHU0:CTBP1_XENLA C-terminal-binding protein 1 - Xenopus laevis (African clawed frog)| Length = 440 Score = 103 bits (256), Expect = 3e-21 Identities = 76/257 (29%), Positives = 123/257 (47%), Gaps = 6/257 (2%) Frame = +2 Query: 455 GYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLP 634 G++N+D+ +A GIA+ N P E T RR Q +R G + Sbjct: 101 GFDNIDIKSAGDLGIAVCNVPAASVEETADSTMCHILNLYRRTTWLHQALREGTRVQSVE 160 Query: 635 HLFV----GNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYG 802 + ++G+T+G+IG GR+G A A + + F N+ ++D Y S +E+ Sbjct: 161 QIREVASGAARIRGETLGIIGLGRVGQAVA-LRAKTFGFNVFFYDPYLSDGIER------ 213 Query: 803 QFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNA 982 A G Q R S+++++L +D ++LH L++ +HLIN + M++ A LVN Sbjct: 214 ----ALGLQ-----RVSTLQDLLFHSDCVTLHCGLNEHNHHLINDFTIKQMRQGAFLVNT 264 Query: 983 SRGPVIDEVALVEHLKANPMFRVGLDVFEDEP--YMKPGLAEMKNAVVVPHIASASKWTR 1156 +RG ++DE AL + LK + LDV E EP + + L + N + PH A S+ Sbjct: 265 ARGGLVDEKALAQALKEGRIRGAALDVHESEPFSFTQGPLKDAPNLICTPHAAWYSEQAS 324 Query: 1157 EGMATLAALNVLGKIKG 1207 M AA + I G Sbjct: 325 IEMREEAAREIRRAITG 341
>Q5EAD2:SERA_BOVIN D-3-phosphoglycerate dehydrogenase - Bos taurus (Bovine)| Length = 533 Score = 102 bits (255), Expect = 3e-21 Identities = 84/311 (27%), Positives = 142/311 (45%), Gaps = 1/311 (0%) Frame = +2 Query: 305 KKTILSVDDILALIGDHCHG-VIGQLTEDWGEVLFSALKRAGGTAFSNMAVGYNNVDVDA 481 +K LS ++++A + D C G ++ T+ +++ +A K G +NVD++A Sbjct: 32 EKQNLSKEELIAELQD-CEGLIVRSATKVTSDIINAAEKLQ---VVGRAGTGVDNVDLEA 87 Query: 482 ANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLPHLFVGNLLK 661 A + GI + NTP + + R+I +A M+ G W F+G L Sbjct: 88 ATRKGILVMNTPNGNSLSAAELTCGMIMCLARQIPQAAASMKDGK---WERKKFMGTELN 144 Query: 662 GQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTW 841 G+ +G++G GRIG A M + F M I +D S + + G Q + Sbjct: 145 GKVLGILGLGRIGREVATRM-QSFGMKTIGYDPIISPEVSA----------SFGVQQLP- 192 Query: 842 KRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVE 1021 +E++ D I++H L +T L+N A KK +VN +RG ++DE AL+ Sbjct: 193 -----LEQIWPLCDFITVHTPLLPSTTGLLNDSTFAQCKKGVCVVNCARGGIVDEGALLR 247 Query: 1022 HLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKI 1201 L++ LDVF +EP L +N + PH+ +++K + AL + + Sbjct: 248 ALQSGQCAGAALDVFTEEPPRDRALVNHENVISCPHLGASTKEAQSRCGEEIALQFVDMV 307 Query: 1202 KGYPVWGNPNA 1234 KG + G NA Sbjct: 308 KGKALAGVVNA 318
>Q5R7M2:SERA_PONPY D-3-phosphoglycerate dehydrogenase - Pongo pygmaeus (Orangutan)| Length = 533 Score = 102 bits (254), Expect = 5e-21 Identities = 85/311 (27%), Positives = 143/311 (45%), Gaps = 1/311 (0%) Frame = +2 Query: 305 KKTILSVDDILALIGDHCHG-VIGQLTEDWGEVLFSALKRAGGTAFSNMAVGYNNVDVDA 481 +K LS ++++A + D C G ++ T+ +V+ +A K G +NVD++A Sbjct: 32 EKQNLSKEELIAELQD-CEGLIVRSATKVTADVINAAEKLQ---VVGRAGTGVDNVDLEA 87 Query: 482 ANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLPHLFVGNLLK 661 A + GI + NTP + + R+I +A M+ G W F+G L Sbjct: 88 ATRKGILVMNTPNGNSLSAAELTCGMIMCLARQIPQATASMKDGK---WERKKFMGTELN 144 Query: 662 GQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTW 841 G+T+G++G GRIG A M + M I +D S + + G Q + Sbjct: 145 GKTLGILGLGRIGREVAIRM-QSLGMKTIGYDPIISPEVSA----------SFGVQQLP- 192 Query: 842 KRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVE 1021 +EE+ D I++H L +T L+N A KK +VN +RG ++DE AL+ Sbjct: 193 -----LEEIWPLCDFITVHTPLLPSTTGLLNDNTFAQCKKGVRVVNCARGGIVDEGALLR 247 Query: 1022 HLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKI 1201 L++ LDVF +EP L + +N + PH+ +++K + A+ + + Sbjct: 248 ALQSGQCAGAALDVFTEEPPRGRALVDHENVISCPHLGASTKEAQSRCGEEIAVQFVDMV 307 Query: 1202 KGYPVWGNPNA 1234 KG + G NA Sbjct: 308 KGKSLTGVVNA 318
>P26297:LDHD_LACDA D-lactate dehydrogenase - Lactobacillus delbrueckii subsp. bulgaricus| (strain ATCC 11842 / DSM 20081) Length = 333 Score = 102 bits (254), Expect = 5e-21 Identities = 86/299 (28%), Positives = 137/299 (45%), Gaps = 17/299 (5%) Frame = +2 Query: 362 GVIGQLTEDWGEVLFSALKRAGGTAFSNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTX 541 GV+ D+ AL G T S VG +N+D+ A + G I N P + Sbjct: 49 GVVVYQQLDYTAETLQALADNGITKMSLRNVGVDNIDMAKAKELGFQITNVPVY----SP 104 Query: 542 XXXXXXXXXXXRRIVEADQFM--RAGLYD-GWLPHLFVGNLLKGQTVGVIGAGRIGSAYA 712 RI+ D+ M + +D W P +G ++ Q VGVIG G IG + Sbjct: 105 NAIAEHAAIQAARILRQDKAMDEKVARHDLRWAPT--IGREVRDQVVGVIGTGHIGQVFM 162 Query: 713 RMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADVIS 892 ++M EGF +I +D++++ LEK G ++ S++++ ++ADVIS Sbjct: 163 QIM-EGFGAKVIAYDIFRNPELEK----KGYYV-------------DSLDDLYKQADVIS 204 Query: 893 LHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFED 1072 LH H+IN E +A MK++ V+VN SRGP++D A++ L + +F +DV+E Sbjct: 205 LHVPDVPANVHMINDESIAKMKQDVVIVNVSRGPLVDTDAVIRGLDSGKIFGYAMDVYEG 264 Query: 1073 E-----------PYMKPGLAEM---KNAVVVPHIASASKWTREGMATLAALNVLGKIKG 1207 E + LA++ N +V PH A + M A N L ++G Sbjct: 265 EVGIFNEDWEGKEFPDARLADLIARPNVLVTPHTAFYTTHAVRNMVVKAFDNNLELVEG 323
>P44501:DDH_HAEIN 2-hydroxyacid dehydrogenase homolog - Haemophilus influenzae| Length = 331 Score = 102 bits (253), Expect = 6e-21 Identities = 73/244 (29%), Positives = 120/244 (49%) Frame = +2 Query: 344 IGDHCHGVIGQLTEDWGEVLFSALKRAGGTAFSNMAVGYNNVDVDAANKNGIAIGNTPGV 523 + +HC V + ++ + L G + G+NNVD+ AA + GI + P Sbjct: 41 LAEHCEVVCIFVNDNGSRKVLEKLAALGVKIVALRCAGFNNVDLKAAQELGIQVVRVPAY 100 Query: 524 LTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLPHLFVGNLLKGQTVGVIGAGRIGS 703 E RRI A Q R + L L +G + G+TVGVIG G+IG Sbjct: 101 SPEAVAEHTIGLMMTLNRRIHRAYQRTREANFS--LEGL-IGFNMYGRTVGVIGTGKIGI 157 Query: 704 AYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREAD 883 A R++ +GF MN++ +D +++ +E+ GQ+++ ++E+ ++ Sbjct: 158 AVMRIL-KGFGMNILAYDPFKNPVVEELG---GQYVE--------------LDELYAKSH 199 Query: 884 VISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDV 1063 VI+LH YHL+N E A MK ++VN SRG +ID A ++ LK + +G+DV Sbjct: 200 VITLHCPATPENYHLLNCEAFAKMKDGVMIVNTSRGSLIDTQAAIDALKQRKIGALGMDV 259 Query: 1064 FEDE 1075 +E+E Sbjct: 260 YENE 263
>P30901:LDHD_LACHE D-lactate dehydrogenase - Lactobacillus helveticus| Length = 337 Score = 101 bits (252), Expect = 8e-21 Identities = 86/296 (29%), Positives = 131/296 (44%), Gaps = 14/296 (4%) Frame = +2 Query: 362 GVIGQLTEDWGEVLFSALKRAGGTAFSNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTX 541 GV+ D+ AL AG T S VG +N+D+D A + G I N P Sbjct: 49 GVVVYQQLDYTADTLQALADAGVTKMSLRNVGVDNIDMDKAKELGFQITNVPVYSPNAIA 108 Query: 542 XXXXXXXXXXXRRIVEADQFMRAGLYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMM 721 R+ D+ M A W P +G ++ Q VGV+G G IG + R+M Sbjct: 109 EHAAIQAARVLRQDKRMDEKM-AKRDLRWAPT--IGREVRDQVVGVVGTGHIGQVFMRIM 165 Query: 722 IEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLHP 901 EGF +I +D++++ LEK G ++ S++++ ++ADVISLH Sbjct: 166 -EGFGAKVIAYDIFKNPELEK----KGYYV-------------DSLDDLYKQADVISLHV 207 Query: 902 VLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDE-- 1075 H+IN + +A MK V+VN SRG ++D A++ L + +F +D +EDE Sbjct: 208 PDVPANVHMINDKSIAEMKDGVVIVNCSRGRLVDTDAVIRGLDSGKIFGFVMDTYEDEVG 267 Query: 1076 ---------PYMKPGLAEM---KNAVVVPHIASASKWTREGMATLAALNVLGKIKG 1207 + LA++ N +V PH A + M A N L I G Sbjct: 268 VFNKDWEGKEFPDKRLADLIDRPNVLVTPHTAFYTTHAVRNMVVKAFNNNLKLING 323
>P30799:DDH_ZYMMO 2-hydroxyacid dehydrogenase homolog - Zymomonas mobilis| Length = 331 Score = 100 bits (248), Expect = 2e-20 Identities = 70/213 (32%), Positives = 100/213 (46%), Gaps = 6/213 (2%) Frame = +2 Query: 455 GYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRI------VEADQFMRAGL 616 GYNNVD+DAA K I + P + R+I V + F GL Sbjct: 78 GYNNVDLDAAKKLNIKVVRVPAYSPYSVAEYAVGMLLTLNRQISRGLKRVRENNFSLEGL 137 Query: 617 YDGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTA 796 +G + +TVG+IG G IGS +A +M GF N+I + + L K V Sbjct: 138 ---------IGLDVHDKTVGIIGVGHIGSVFAHIMTHGFGANVIAYKPHPDPELAKKVGF 188 Query: 797 YGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLV 976 R +S++EV+ +D+ISLH L +H+IN E LA KK LV Sbjct: 189 ----------------RFTSLDEVIETSDIISLHCPLTPENHHMINEETLARAKKGFYLV 232 Query: 977 NASRGPVIDEVALVEHLKANPMFRVGLDVFEDE 1075 N SRG ++D A+++ LKA + DV+E+E Sbjct: 233 NTSRGGLVDTKAVIKSLKAKHLGGYAADVYEEE 265
>O46036:CTBP_DROME C-terminal-binding protein - Drosophila melanogaster (Fruit fly)| Length = 476 Score = 100 bits (248), Expect = 2e-20 Identities = 83/297 (27%), Positives = 132/297 (44%), Gaps = 16/297 (5%) Frame = +2 Query: 455 GYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLP 634 G +N+DV AA + GIA+ N PG E RR +R G Sbjct: 101 GTDNIDVKAAGELGIAVCNVPGYGVEEVADTTMCLILNLYRRTYWLANMVREG------- 153 Query: 635 HLFVGN-----------LLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLE 781 F G ++G T+G++G GRIGSA A + + F N+I++D Y ++ Sbjct: 154 KKFTGPEQVREAAHGCARIRGDTLGLVGLGRIGSAVA-LRAKAFGFNVIFYDPYLPDGID 212 Query: 782 KFVTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKK 961 K + R +++++L ++D +SLH L++ +HLIN + M+ Sbjct: 213 KSLGL---------------TRVYTLQDLLFQSDCVSLHCTLNEHNHHLINEFTIKQMRP 257 Query: 962 EAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEPY--MKPGLAEMKNAVVVPHIA 1135 A LVN +RG ++D+ L LK + LDV E+EPY + L + N + PH A Sbjct: 258 GAFLVNTARGGLVDDETLALALKQGRIRAAALDVHENEPYNVFQGALKDAPNLICTPHAA 317 Query: 1136 SASKWTREGMATLAALNVLGKIKGYPVWGNPNAVEPFLDEE---ATPPPACPSIVNA 1297 S + + +AA + I G P+ + +++E TPP A V A Sbjct: 318 FFSDASATELREMAATEIRRAIVG----NIPDVLRNCVNKEYFMRTPPAAAAGGVAA 370
>P73821:SERA_SYNY3 D-3-phosphoglycerate dehydrogenase - Synechocystis sp. (strain PCC| 6803) Length = 554 Score = 99.0 bits (245), Expect = 5e-20 Identities = 72/254 (28%), Positives = 117/254 (46%) Frame = +2 Query: 452 VGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWL 631 VG +N+DV AA + GI + N+P T R I +A++ ++ W Sbjct: 100 VGVDNIDVPAATRQGIVVVNSPEGNTIAAAEHALAMMMALARHIPDANKSVKESK---WE 156 Query: 632 PHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFL 811 F+G + +T+GV+G G+IGS A + + M L+ +D + S + Sbjct: 157 RKQFIGTEVYKKTLGVVGLGKIGSHVAGVA-KAMGMKLLAYDPFISQERADQIGC----- 210 Query: 812 KANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRG 991 ++ + EAD I+LH T +LIN E LA MK A ++N SRG Sbjct: 211 -----------TLVDLDLLFSEADFITLHIPKTPETANLINAETLAKMKPTARIINCSRG 259 Query: 992 PVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMAT 1171 +IDE ALV ++ + LDVF EP + L E N ++ PH+ ++++ + +A Sbjct: 260 GIIDEEALVTAIETAQIGGAALDVFAQEPLGESRLREFSNVILTPHLGASTEEAQVNVAV 319 Query: 1172 LAALNVLGKIKGYP 1213 A + + G P Sbjct: 320 DVAEQIRDVLLGLP 333
>Q59642:LDHD_PEDAC D-lactate dehydrogenase - Pediococcus acidilactici| Length = 331 Score = 97.4 bits (241), Expect = 1e-19 Identities = 81/289 (28%), Positives = 129/289 (44%), Gaps = 14/289 (4%) Frame = +2 Query: 362 GVIGQLTEDWGEVLFSALKRAGGTAFSNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTX 541 GV+ + + LF + G AFS VG +NV DA KN I I N P Sbjct: 47 GVVAYQQKPYTADLFDKMHEFGIHAFSLRNVGLDNVPADALKKNDIKISNVPAYSPRAIA 106 Query: 542 XXXXXXXXXXXRRIVEADQFMRAGLYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMM 721 R+I E + M G Y W P +G L TVGVIG GRIG A A + Sbjct: 107 ELSVTQLLALLRKIPEFEYKMAHGDYR-WEPD--IGLELNQMTVGVIGTGRIGRA-AIDI 162 Query: 722 IEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLHP 901 + F +I +D++++ LEK G ++ ++EE+ ++A+VI+LH Sbjct: 163 FKPFGAKVIAYDVFRNPALEK----EGMYV-------------DTLEELYQQANVITLHV 205 Query: 902 VLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFE---- 1069 K YH+++ + M+ ++N +RG ++D AL++ L + + LD +E Sbjct: 206 PALKDNYHMLDEKAFGQMQDGTFILNFARGTLVDTPALLKALDSGKVAGAALDTYENEVG 265 Query: 1070 -------DEPYMKP---GLAEMKNAVVVPHIASASKWTREGMATLAALN 1186 D+P P L +N ++ PH A ++ + M +A N Sbjct: 266 IFDVDHGDQPIDDPVFNDLMSRRNVMITPHAAFYTRPAVKNMVQIALDN 314
>P43885:SERA_HAEIN D-3-phosphoglycerate dehydrogenase - Haemophilus influenzae| Length = 410 Score = 97.1 bits (240), Expect = 2e-19 Identities = 72/259 (27%), Positives = 121/259 (46%), Gaps = 6/259 (2%) Frame = +2 Query: 452 VGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWL 631 +G N VD++AA GI + N P T + R + +A+ + G+ W Sbjct: 85 IGTNQVDLNAAKARGIPVFNAPFSNTRSVAELVLGEILLLMRNVPQANAEVHRGV---WN 141 Query: 632 PHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFL 811 + ++G+ +G+IG G IGS + ++ E M++ ++D+ L Sbjct: 142 KSATGSHEVRGKKLGIIGYGHIGSQLS-IIAESLGMDVYFYDIENKLPLGNA-------- 192 Query: 812 KANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRG 991 K+ S+EE+L DV+SLH +T +L+N R+A +K+ A+L+NA+RG Sbjct: 193 ----------KQVRSLEELLSSCDVVSLHVPELPSTKNLMNVARIAQLKQGAILINAARG 242 Query: 992 PVIDEVALVEHLKANPMFRVGLDVFEDEP------YMKPGLAEMKNAVVVPHIASASKWT 1153 V+D AL + LK + +DVF EP ++ P L E N ++ PHI ++ Sbjct: 243 TVVDIDALAQALKDGKLQGAAIDVFPVEPASINEEFISP-LREFDNVILTPHIGGSTAEA 301 Query: 1154 REGMATLAALNVLGKIKGY 1210 +E + V GK Y Sbjct: 302 QENI----GFEVAGKFVKY 316
>P45250:Y1556_HAEIN Putative 2-hydroxyacid dehydrogenase HI1556 - Haemophilus influenzae| Length = 315 Score = 94.0 bits (232), Expect = 2e-18 Identities = 74/243 (30%), Positives = 109/243 (44%), Gaps = 11/243 (4%) Frame = +2 Query: 449 AVGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGW 628 A G NNVD+ AA + GIA+ N G + T + ++R W Sbjct: 72 ATGTNNVDLVAAEEMGIAVRNVTGYSSTTVPEHVIGLIFSLKHSLAG---WLRDQTEAKW 128 Query: 629 LPHL------FVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFV 790 + ++G T+GV G G +G+ R+ M ++Y + +T + Sbjct: 129 AESKQFCYFDYPITDVRGSTLGVFGKGCLGTEVGRLA-NAVGMKVLYAEHKDATVCREGY 187 Query: 791 TAYGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAV 970 T + +EVL++AD+++LH L +TT LIN E L+ MKK A Sbjct: 188 TPF--------------------DEVLKQADIVTLHCPLTETTKDLINAETLSKMKKGAF 227 Query: 971 LVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKP-----GLAEMKNAVVVPHIA 1135 L+N RGP+IDE+ALV+ LK + LDV EP K M N ++ PHIA Sbjct: 228 LINTGRGPLIDELALVDALKTGHLGGAALDVMVKEPPEKDNPLILAAKTMPNLIITPHIA 287 Query: 1136 SAS 1144 AS Sbjct: 288 WAS 290
>Q6GDS2:LDHD_STAAR D-lactate dehydrogenase - Staphylococcus aureus (strain MRSA252)| Length = 330 Score = 91.7 bits (226), Expect = 8e-18 Identities = 74/269 (27%), Positives = 123/269 (45%), Gaps = 14/269 (5%) Frame = +2 Query: 371 GQLTEDWGEVLFSALKRAGGTAFSNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTXXXX 550 G+L D ++ L+ G + G++ D+D A K+ I I N P ET Sbjct: 55 GKLEND----VYPKLESYGIKQIAQRTAGFDMYDLDLAKKHNIVISNVPSYSPETIAEYS 110 Query: 551 XXXXXXXXRRIVEADQFMRAGLYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEG 730 RR + ++ ++A + W + + +K TV +IG GRIG+A A++ G Sbjct: 111 VSIALQLVRRFPDIERRVQAHDFT-WQAEI-MSKPVKNMTVAIIGTGRIGAATAKIYA-G 167 Query: 731 FKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLD 910 F + +D Y + L+ FL T+K S++E +++AD+ISLH + Sbjct: 168 FGATITAYDAYPNKDLD--------FL--------TYK--DSVKEAIKDADIISLHVPAN 209 Query: 911 KTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKP 1090 K +YHL + +KK A+LVNA+RG VI+ L++ + + +D +E+E Sbjct: 210 KESYHLFDKTMFDHVKKGAILVNAARGAVINTPDLIDAVNDGTLLGAAIDTYENEAAYFT 269 Query: 1091 G--------------LAEMKNAVVVPHIA 1135 L E + +V PHIA Sbjct: 270 NDWTNKDIDDKTLLELIEHERILVTPHIA 298
>Q8NUT2:LDHD_STAAW D-lactate dehydrogenase - Staphylococcus aureus (strain MW2)| Length = 330 Score = 91.3 bits (225), Expect = 1e-17 Identities = 74/269 (27%), Positives = 123/269 (45%), Gaps = 14/269 (5%) Frame = +2 Query: 371 GQLTEDWGEVLFSALKRAGGTAFSNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTXXXX 550 G+L +D ++ L+ G + G++ D+D A K+ I I N P ET Sbjct: 55 GKLEDD----VYPKLESYGIKQIAQRTAGFDMYDLDLAKKHNIVISNVPSYSPETIAEYS 110 Query: 551 XXXXXXXXRRIVEADQFMRAGLYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEG 730 RR + ++ ++A + W + + +K TV +IG GRIG+A A++ G Sbjct: 111 VSIALQLVRRFPDIERRVQAHDFT-WQAEI-MSKPVKNMTVAIIGTGRIGAATAKIYA-G 167 Query: 731 FKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLD 910 F + +D Y + L+ FL T+K S++E +++AD+ISLH + Sbjct: 168 FGATITAYDAYPNKDLD--------FL--------TYK--DSVKEAIKDADIISLHVPAN 209 Query: 911 KTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKP 1090 K +YHL + +KK A+LVNA+RG VI+ L+ + + +D +E+E Sbjct: 210 KESYHLFDKAMFDHVKKGAILVNAARGAVINTPDLIAAVNDGTLLGAAIDTYENEAAYFT 269 Query: 1091 G--------------LAEMKNAVVVPHIA 1135 L E + +V PHIA Sbjct: 270 NDWTNKDIDDKTLLELIEHERILVTPHIA 298
>Q6G6F1:LDHD_STAAS D-lactate dehydrogenase - Staphylococcus aureus (strain MSSA476)| Length = 330 Score = 91.3 bits (225), Expect = 1e-17 Identities = 74/269 (27%), Positives = 123/269 (45%), Gaps = 14/269 (5%) Frame = +2 Query: 371 GQLTEDWGEVLFSALKRAGGTAFSNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTXXXX 550 G+L +D ++ L+ G + G++ D+D A K+ I I N P ET Sbjct: 55 GKLEDD----VYPKLESYGIKQIAQRTAGFDMYDLDLAKKHNIVISNVPSYSPETIAEYS 110 Query: 551 XXXXXXXXRRIVEADQFMRAGLYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEG 730 RR + ++ ++A + W + + +K TV +IG GRIG+A A++ G Sbjct: 111 VSIALQLVRRFPDIERRVQAHDFT-WQAEI-MSKPVKNMTVAIIGTGRIGAATAKIYA-G 167 Query: 731 FKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLD 910 F + +D Y + L+ FL T+K S++E +++AD+ISLH + Sbjct: 168 FGATITAYDAYPNKDLD--------FL--------TYK--DSVKEAIKDADIISLHVPAN 209 Query: 911 KTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKP 1090 K +YHL + +KK A+LVNA+RG VI+ L+ + + +D +E+E Sbjct: 210 KESYHLFDKAMFDHVKKGAILVNAARGAVINTPDLIAAVNDGTLLGAAIDTYENEAAYFT 269 Query: 1091 G--------------LAEMKNAVVVPHIA 1135 L E + +V PHIA Sbjct: 270 NDWTNKDIDDKTLLELIEHERILVTPHIA 298
>P72357:LDHD_STAAU D-lactate dehydrogenase - Staphylococcus aureus| Length = 330 Score = 90.5 bits (223), Expect = 2e-17 Identities = 74/269 (27%), Positives = 122/269 (45%), Gaps = 14/269 (5%) Frame = +2 Query: 371 GQLTEDWGEVLFSALKRAGGTAFSNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTXXXX 550 G+L D ++ L+ G + G++ D+D A K+ I I N P ET Sbjct: 55 GKLEND----VYPKLESYGIKQIAQRTAGFDMYDLDLAKKHNIVISNVPSYSPETIAEYS 110 Query: 551 XXXXXXXXRRIVEADQFMRAGLYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEG 730 RR + ++ ++A + W + + +K TV +IG GRIG+A A++ G Sbjct: 111 VSIALQLVRRFPDIERRVQAHDFT-WQAEI-MSKPVKNMTVAIIGTGRIGAATAKIYA-G 167 Query: 731 FKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLD 910 F + +D Y + L+ FL T+K S++E +++AD+ISLH + Sbjct: 168 FGATITAYDAYPNKDLD--------FL--------TYK--DSVKEAIKDADIISLHVPAN 209 Query: 911 KTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKP 1090 K +YHL + +KK A+LVNA+RG VI+ L+ + + +D +E+E Sbjct: 210 KESYHLFDKAMFDHVKKGAILVNAARGAVINTPDLIAAVNDGTLLGAAIDTYENEAAYFT 269 Query: 1091 G--------------LAEMKNAVVVPHIA 1135 L E + +V PHIA Sbjct: 270 NDWTNKDIDDKTLLELIEHERILVTPHIA 298
>Q5HD29:LDHD_STAAC D-lactate dehydrogenase - Staphylococcus aureus (strain COL)| Length = 330 Score = 90.5 bits (223), Expect = 2e-17 Identities = 74/269 (27%), Positives = 122/269 (45%), Gaps = 14/269 (5%) Frame = +2 Query: 371 GQLTEDWGEVLFSALKRAGGTAFSNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTXXXX 550 G+L D ++ L+ G + G++ D+D A K+ I I N P ET Sbjct: 55 GKLEND----VYPKLESYGIKQIAQRTAGFDMYDLDLAKKHNIVISNVPSYSPETIAEYS 110 Query: 551 XXXXXXXXRRIVEADQFMRAGLYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEG 730 RR + ++ ++A + W + + +K TV +IG GRIG+A A++ G Sbjct: 111 VSIALQLVRRFPDIERRVQAHDFT-WQAEI-MSKPVKNMTVAIIGTGRIGAATAKIYA-G 167 Query: 731 FKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLD 910 F + +D Y + L+ FL T+K S++E +++AD+ISLH + Sbjct: 168 FGATITAYDAYPNKDLD--------FL--------TYK--DSVKEAIKDADIISLHVPAN 209 Query: 911 KTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKP 1090 K +YHL + +KK A+LVNA+RG VI+ L+ + + +D +E+E Sbjct: 210 KESYHLFDKAMFDHVKKGAILVNAARGAVINTPDLIAAVNDGTLLGAAIDTYENEAAYFT 269 Query: 1091 G--------------LAEMKNAVVVPHIA 1135 L E + +V PHIA Sbjct: 270 NDWTNKDIDDKTLLELIEHERILVTPHIA 298
>P0A9T3:SERA_SHIFL D-3-phosphoglycerate dehydrogenase - Shigella flexneri| Length = 410 Score = 90.1 bits (222), Expect = 2e-17 Identities = 70/265 (26%), Positives = 121/265 (45%), Gaps = 6/265 (2%) Frame = +2 Query: 434 AFSNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAG 613 A +G N VD+DAA K GI + N P T + R + EA+ G Sbjct: 78 AIGCFCIGTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLLLRGVPEANAKAHRG 137 Query: 614 LYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVT 793 +++ F +G+ +G+IG G IG+ ++ E M + ++D+ L Sbjct: 138 VWNKLAAGSFEA---RGKKLGIIGYGHIGTQLG-ILAESLGMYVYFYDIENKLPL----- 188 Query: 794 AYGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVL 973 N Q + ++L +DV+SLH + +T +++ + +++MK ++L Sbjct: 189 -------GNATQ------VQHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLL 235 Query: 974 VNASRGPVIDEVALVEHLKANPMFRVGLDVFEDE------PYMKPGLAEMKNAVVVPHIA 1135 +NASRG V+D AL + L + + +DVF E P+ P L E N ++ PHI Sbjct: 236 INASRGTVVDIPALCDALASKHLAGAAIDVFPTEPATNSDPFTSP-LCEFDNVLLTPHIG 294 Query: 1136 SASKWTREGMATLAALNVLGKIKGY 1210 +++ +E + L V GK+ Y Sbjct: 295 GSTQEAQENI----GLEVAGKLIKY 315
>P0A9T0:SERA_ECOLI D-3-phosphoglycerate dehydrogenase - Escherichia coli| Length = 410 Score = 90.1 bits (222), Expect = 2e-17 Identities = 70/265 (26%), Positives = 121/265 (45%), Gaps = 6/265 (2%) Frame = +2 Query: 434 AFSNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAG 613 A +G N VD+DAA K GI + N P T + R + EA+ G Sbjct: 78 AIGCFCIGTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLLLRGVPEANAKAHRG 137 Query: 614 LYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVT 793 +++ F +G+ +G+IG G IG+ ++ E M + ++D+ L Sbjct: 138 VWNKLAAGSFEA---RGKKLGIIGYGHIGTQLG-ILAESLGMYVYFYDIENKLPL----- 188 Query: 794 AYGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVL 973 N Q + ++L +DV+SLH + +T +++ + +++MK ++L Sbjct: 189 -------GNATQ------VQHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLL 235 Query: 974 VNASRGPVIDEVALVEHLKANPMFRVGLDVFEDE------PYMKPGLAEMKNAVVVPHIA 1135 +NASRG V+D AL + L + + +DVF E P+ P L E N ++ PHI Sbjct: 236 INASRGTVVDIPALCDALASKHLAGAAIDVFPTEPATNSDPFTSP-LCEFDNVLLTPHIG 294 Query: 1136 SASKWTREGMATLAALNVLGKIKGY 1210 +++ +E + L V GK+ Y Sbjct: 295 GSTQEAQENI----GLEVAGKLIKY 315
>P0A9T1:SERA_ECOL6 D-3-phosphoglycerate dehydrogenase - Escherichia coli O6| Length = 410 Score = 90.1 bits (222), Expect = 2e-17 Identities = 70/265 (26%), Positives = 121/265 (45%), Gaps = 6/265 (2%) Frame = +2 Query: 434 AFSNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAG 613 A +G N VD+DAA K GI + N P T + R + EA+ G Sbjct: 78 AIGCFCIGTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLLLRGVPEANAKAHRG 137 Query: 614 LYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVT 793 +++ F +G+ +G+IG G IG+ ++ E M + ++D+ L Sbjct: 138 VWNKLAAGSFEA---RGKKLGIIGYGHIGTQLG-ILAESLGMYVYFYDIENKLPL----- 188 Query: 794 AYGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVL 973 N Q + ++L +DV+SLH + +T +++ + +++MK ++L Sbjct: 189 -------GNATQ------VQHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLL 235 Query: 974 VNASRGPVIDEVALVEHLKANPMFRVGLDVFEDE------PYMKPGLAEMKNAVVVPHIA 1135 +NASRG V+D AL + L + + +DVF E P+ P L E N ++ PHI Sbjct: 236 INASRGTVVDIPALCDALASKHLAGAAIDVFPTEPATNSDPFTSP-LCEFDNVLLTPHIG 294 Query: 1136 SASKWTREGMATLAALNVLGKIKGY 1210 +++ +E + L V GK+ Y Sbjct: 295 GSTQEAQENI----GLEVAGKLIKY 315
>P0A9T2:SERA_ECO57 D-3-phosphoglycerate dehydrogenase - Escherichia coli O157:H7| Length = 410 Score = 90.1 bits (222), Expect = 2e-17 Identities = 70/265 (26%), Positives = 121/265 (45%), Gaps = 6/265 (2%) Frame = +2 Query: 434 AFSNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAG 613 A +G N VD+DAA K GI + N P T + R + EA+ G Sbjct: 78 AIGCFCIGTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLLLRGVPEANAKAHRG 137 Query: 614 LYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVT 793 +++ F +G+ +G+IG G IG+ ++ E M + ++D+ L Sbjct: 138 VWNKLAAGSFEA---RGKKLGIIGYGHIGTQLG-ILAESLGMYVYFYDIENKLPL----- 188 Query: 794 AYGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVL 973 N Q + ++L +DV+SLH + +T +++ + +++MK ++L Sbjct: 189 -------GNATQ------VQHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLL 235 Query: 974 VNASRGPVIDEVALVEHLKANPMFRVGLDVFEDE------PYMKPGLAEMKNAVVVPHIA 1135 +NASRG V+D AL + L + + +DVF E P+ P L E N ++ PHI Sbjct: 236 INASRGTVVDIPALCDALASKHLAGAAIDVFPTEPATNSDPFTSP-LCEFDNVLLTPHIG 294 Query: 1136 SASKWTREGMATLAALNVLGKIKGY 1210 +++ +E + L V GK+ Y Sbjct: 295 GSTQEAQENI----GLEVAGKLIKY 315
>P99116:LDHD_STAAN D-lactate dehydrogenase - Staphylococcus aureus (strain N315)| Length = 330 Score = 90.1 bits (222), Expect = 2e-17 Identities = 74/269 (27%), Positives = 119/269 (44%), Gaps = 14/269 (5%) Frame = +2 Query: 371 GQLTEDWGEVLFSALKRAGGTAFSNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTXXXX 550 G+L D ++ L+ G + G++ D+D A K+ I I N P ET Sbjct: 55 GKLEND----VYPKLESYGIKQIAQRTAGFDMYDLDLAKKHNIVISNVPSYSPETIAEYS 110 Query: 551 XXXXXXXXRRIVEADQFMRAGLYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEG 730 RR + ++ R +D + +K TV +IG GRIG+A A++ G Sbjct: 111 VSIALQLVRRFPDIER--RVQTHDFTWQAEIMSKPVKNMTVAIIGTGRIGAATAKIYA-G 167 Query: 731 FKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLD 910 F + +D Y + L+ FL T+K S++E +++AD+ISLH + Sbjct: 168 FGATITAYDAYPNKDLD--------FL--------TYK--DSVKEAIKDADIISLHVPAN 209 Query: 911 KTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKP 1090 K +YHL + +KK A+LVNA+RG VI+ L+ + + +D +E+E Sbjct: 210 KESYHLFDKAMFDHVKKGAILVNAARGAVINTPDLIAAVNDGTLLGAAIDTYENEAAYFT 269 Query: 1091 G--------------LAEMKNAVVVPHIA 1135 L E + +V PHIA Sbjct: 270 NDWTNKDIDDKTLLELIEHERILVTPHIA 298
>P63940:LDHD_STAAM D-lactate dehydrogenase - Staphylococcus aureus (strain Mu50 / ATCC| 700699) Length = 330 Score = 90.1 bits (222), Expect = 2e-17 Identities = 74/269 (27%), Positives = 119/269 (44%), Gaps = 14/269 (5%) Frame = +2 Query: 371 GQLTEDWGEVLFSALKRAGGTAFSNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTXXXX 550 G+L D ++ L+ G + G++ D+D A K+ I I N P ET Sbjct: 55 GKLEND----VYPKLESYGIKQIAQRTAGFDMYDLDLAKKHNIVISNVPSYSPETIAEYS 110 Query: 551 XXXXXXXXRRIVEADQFMRAGLYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEG 730 RR + ++ R +D + +K TV +IG GRIG+A A++ G Sbjct: 111 VSIALQLVRRFPDIER--RVQTHDFTWQAEIMSKPVKNMTVAIIGTGRIGAATAKIYA-G 167 Query: 731 FKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLD 910 F + +D Y + L+ FL T+K S++E +++AD+ISLH + Sbjct: 168 FGATITAYDAYPNKDLD--------FL--------TYK--DSVKEAIKDADIISLHVPAN 209 Query: 911 KTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKP 1090 K +YHL + +KK A+LVNA+RG VI+ L+ + + +D +E+E Sbjct: 210 KESYHLFDKAMFDHVKKGAILVNAARGAVINTPDLIAAVNDGTLLGAAIDTYENEAAYFT 269 Query: 1091 G--------------LAEMKNAVVVPHIA 1135 L E + +V PHIA Sbjct: 270 NDWTNKDIDDKTLLELIEHERILVTPHIA 298
>Q59516:DHGY_METEX Glycerate dehydrogenase - Methylobacterium extorquens (Protomonas| extorquens) Length = 314 Score = 90.1 bits (222), Expect = 2e-17 Identities = 72/261 (27%), Positives = 113/261 (43%), Gaps = 6/261 (2%) Frame = +2 Query: 449 AVGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGW 628 A G + VD AA GI + N T R IV +R G ++ Sbjct: 73 ATGTDVVDKAAAKAQGITVVNIRNYAFNTVPEHVVGLMFALRRAIVPYANSVRRGDWNKS 132 Query: 629 LPHLFVGNLL---KGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAY 799 + + G T+G+IG G +G + A+ E M ++ FD++ L Sbjct: 133 KQFCYFDYPIYDIAGSTLGIIGYGALGKSIAKRA-EALGMKVLAFDVFPQDGLV------ 185 Query: 800 GQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVN 979 +E +L ++DVI+LH L T ++I E+L MK+ A+L+N Sbjct: 186 ------------------DLETILTQSDVITLHVPLTPDTKNMIGAEQLKKMKRSAILIN 227 Query: 980 ASRGPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGL---AEMKNAVVVPHIASASKW 1150 +RG ++DE AL++ LK + G DV EP + A++ N +V PH+A ASK Sbjct: 228 TARGGLVDEAALLQALKDGTIGGAGFDVVAQEPPKDGNILCDADLPNLIVTPHVAWASKE 287 Query: 1151 TREGMATLAALNVLGKIKGYP 1213 + +A NV + G P Sbjct: 288 AMQILADQLVDNVEAFVAGKP 308
>P87228:SERA_SCHPO Putative D-3-phosphoglycerate dehydrogenase - Schizosaccharomyces| pombe (Fission yeast) Length = 466 Score = 88.6 bits (218), Expect = 7e-17 Identities = 76/296 (25%), Positives = 132/296 (44%), Gaps = 16/296 (5%) Frame = +2 Query: 308 KTILSVDDILALI-GDHCHGVIGQ--LTEDWGEVLFSALKRAGGTAFSNMAVGYNNVDVD 478 KT +S DD++ I G H G+ + LT E S + +G N VD+D Sbjct: 83 KTSMSEDDLVEKIKGVHAIGIRSKTRLTRRVLEAADSLI------VIGCFCIGTNQVDLD 136 Query: 479 AANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLPHLFVGNLL 658 A + GIA+ N+P + + R++ + + G ++ + + Sbjct: 137 FAAERGIAVFNSPYANSRSVAELVIGYIISLARQVGDRSLELHRGEWNKVSSGCWE---I 193 Query: 659 KGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVT 838 +G+T+G+IG G IGS + ++ E ++++Y+D+ L Sbjct: 194 RGKTLGIIGYGHIGSQLS-VLAEAMGLHVVYYDILPIMPLGSA----------------- 235 Query: 839 WKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALV 1018 K+ SS+ E+L AD +SLH T ++I+ + A MK+ + L+NASRG V+D ALV Sbjct: 236 -KQLSSLPELLHRADFVSLHVPASPETKNMISSKEFAAMKEGSYLINASRGTVVDIPALV 294 Query: 1019 EHLKANPMFRVGLDVFEDEP-------------YMKPGLAEMKNAVVVPHIASASK 1147 + K+ + +DV+ EP L KN ++ PHI +++ Sbjct: 295 DASKSGKIAGAAIDVYPSEPAGNGKDKFVDSLNSWTSELTHCKNIILTPHIGGSTE 350
>P51011:LDHD_LEUMC D-lactate dehydrogenase - Leuconostoc mesenteroides subsp. cremoris| Length = 331 Score = 87.8 bits (216), Expect = 1e-16 Identities = 76/265 (28%), Positives = 120/265 (45%), Gaps = 15/265 (5%) Frame = +2 Query: 386 DWGEVLFSALKRAGGTAFSNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXX 565 D+ +AL G T S VG +N+D DAA + I N P Sbjct: 56 DYTRETLTALANVGVTNLSLRNVGTDNIDFDAAREFNFNISNVPVYSPNAIAEHSMLQLS 115 Query: 566 XXXRRIVEAD-QFMRAGLYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMN 742 RR D + + L W P G ++ QTVGVIG G IG A +++GF Sbjct: 116 RLLRRTKALDAKIAKRDLR--WAPT--TGREMRMQTVGVIGTGHIGRV-AINILKGFGAK 170 Query: 743 LIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTY 922 +I +D Y + L+ A G ++ +++E+ +AD ISL+ + Sbjct: 171 VIAYDKYPNAELQ----AEGLYV-------------DTLDELYAQADAISLYVPGVPENH 213 Query: 923 HLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEP--YMKPGL 1096 HLIN + +A MK V++NA+RG ++D A+++ L + + G+DV+E+E MK GL Sbjct: 214 HLINADAIAKMKDGVVIMNAARGNLMDIDAIIDGLNSGKISDFGMDVYENEVACSMKIGL 273 Query: 1097 AE------------MKNAVVVPHIA 1135 + +N ++ PH A Sbjct: 274 VKNSPDAKIADLIARENVMITPHTA 298
>P40054:SERA_YEAST D-3-phosphoglycerate dehydrogenase 1 - Saccharomyces cerevisiae| (Baker's yeast) Length = 469 Score = 87.4 bits (215), Expect = 2e-16 Identities = 62/246 (25%), Positives = 119/246 (48%), Gaps = 14/246 (5%) Frame = +2 Query: 452 VGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWL 631 +G N VD+D A GIA+ N+P + + R++ + + G ++ Sbjct: 131 IGTNQVDLDYATSRGIAVFNSPFSNSRSVAELVIAEIISLARQLGDRSIELHTGTWNKVA 190 Query: 632 PHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFL 811 + ++G+T+G+IG G IGS + ++ E ++++Y+D+ + A G Sbjct: 191 ARCWE---VRGKTLGIIGYGHIGSQLS-VLAEAMGLHVLYYDIVT-------IMALG--- 236 Query: 812 KANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRG 991 T ++ S+++E+L ++D ++LH T +++ + A MK A ++NASRG Sbjct: 237 --------TARQVSTLDELLNKSDFVTLHVPATPETEKMLSAPQFAAMKDGAYVINASRG 288 Query: 992 PVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPG--------------LAEMKNAVVVPH 1129 V+D +L++ +KAN + LDV+ EP K G L + N ++ PH Sbjct: 289 TVVDIPSLIQAVKANKIAGAALDVYPHEP-AKNGEGSFNDELNSWTSELVSLPNIILTPH 347 Query: 1130 IASASK 1147 I +++ Sbjct: 348 IGGSTE 353
>Q8CN22:LDHD_STAES D-lactate dehydrogenase - Staphylococcus epidermidis (strain ATCC| 12228) Length = 330 Score = 87.4 bits (215), Expect = 2e-16 Identities = 76/297 (25%), Positives = 130/297 (43%), Gaps = 18/297 (6%) Frame = +2 Query: 299 TEKKTILSVDDILALIGDHCHGVIGQLTEDWGEV---LFSALKRAGGTAFSNMAVGYNNV 469 T +LSVD + D G T +G++ ++ L+ G + G++ Sbjct: 29 TTSTELLSVDTV-----DQLKDYDGVTTMQFGKLEPEVYPKLESYGIKQIAQRTAGFDMY 83 Query: 470 DVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLPHLFVG 649 D++ A K+ I I N P ET R+ ++ ++A + P + Sbjct: 84 DLELAKKHEIIISNIPSYSPETIAEYSVSIALQLVRKFPTIEKRVQAHNFTWASP--IMS 141 Query: 650 NLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQ 829 +K TV +IG GRIG+A ++ GF ++ +D Y + L FL+ Sbjct: 142 RPVKNMTVAIIGTGRIGAATGKIYA-GFGARVVGYDAYPNHSLS--------FLEYK--- 189 Query: 830 PVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEV 1009 ++E+ +++AD+ISLH +K ++HL + +KK AVLVNA+RG VI+ Sbjct: 190 -------ETVEDAIKDADIISLHVPANKDSFHLFDNNMFKNVKKGAVLVNAARGAVINTP 242 Query: 1010 ALVEHLKANPMFRVGLDVFE---------------DEPYMKPGLAEMKNAVVVPHIA 1135 L+E + + +D +E D+P + L +N +V PHIA Sbjct: 243 DLIEAVNNGTLSGAAIDTYENEANYFTFDCSNQTIDDPILL-DLIRNENILVTPHIA 298
>Q5HLA0:LDHD_STAEQ D-lactate dehydrogenase - Staphylococcus epidermidis (strain ATCC| 35984 / RP62A) Length = 330 Score = 87.4 bits (215), Expect = 2e-16 Identities = 76/297 (25%), Positives = 130/297 (43%), Gaps = 18/297 (6%) Frame = +2 Query: 299 TEKKTILSVDDILALIGDHCHGVIGQLTEDWGEV---LFSALKRAGGTAFSNMAVGYNNV 469 T +LSVD + D G T +G++ ++ L+ G + G++ Sbjct: 29 TTSTELLSVDTV-----DQLKDYDGVTTMQFGKLEPEVYPKLESYGIKQIAQRTAGFDMY 83 Query: 470 DVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLPHLFVG 649 D++ A K+ I I N P ET R+ ++ ++A + P + Sbjct: 84 DLELAKKHEIIISNIPSYSPETIAEYSVSIALQLVRKFPTIEKRVQAHNFTWASP--IMS 141 Query: 650 NLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQ 829 +K TV +IG GRIG+A ++ GF ++ +D Y + L FL+ Sbjct: 142 RPVKNMTVAIIGTGRIGAATGKIYA-GFGARVVGYDAYPNHSLS--------FLEYK--- 189 Query: 830 PVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEV 1009 ++E+ +++AD+ISLH +K ++HL + +KK AVLVNA+RG VI+ Sbjct: 190 -------ETVEDAIKDADIISLHVPANKDSFHLFDNNMFKNVKKGAVLVNAARGAVINTP 242 Query: 1010 ALVEHLKANPMFRVGLDVFE---------------DEPYMKPGLAEMKNAVVVPHIA 1135 L+E + + +D +E D+P + L +N +V PHIA Sbjct: 243 DLIEAVNNGTLSGAAIDTYENEANYFTFDCSNQTIDDPILL-DLIRNENILVTPHIA 298
>O83080:LDHD_TREPA D-lactate dehydrogenase - Treponema pallidum| Length = 331 Score = 85.5 bits (210), Expect = 6e-16 Identities = 71/256 (27%), Positives = 108/256 (42%), Gaps = 14/256 (5%) Frame = +2 Query: 440 SNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLY 619 S G++ + K+GI + N P R E + F+R + Sbjct: 74 STRTAGFDMYNATLLKKHGIRLTNVPSYSPNAIGEYALAAALQLTRHAREIETFVRKRDF 133 Query: 620 DGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAY 799 P L L+ VG++G GRIG A AR+ +G ++ FD Y + ++++T Sbjct: 134 RWQKPIL--SKELRCSRVGILGTGRIGQAAARLF-KGVGAQVVGFDPYPNDAAKEWLTYV 190 Query: 800 GQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVN 979 SM+E+L +DVISLH K ++HLIN + +A MK LVN Sbjct: 191 ------------------SMDELLSTSDVISLHMPATKDSHHLINAKTIAQMKDGVYLVN 232 Query: 980 ASRGPVIDEVALVEHLKANPMFRVGLDVFEDE-PYMKPG-------------LAEMKNAV 1117 +RG VID AL++ L + LD +E E PY+ L + + Sbjct: 233 TARGAVIDSQALLDSLDKGKIAGAALDAYEFEGPYIPKDNGNNPITDTVYARLVAHERII 292 Query: 1118 VVPHIASASKWTREGM 1165 PHIA ++ E M Sbjct: 293 YTPHIAFYTETAIENM 308
>Q8DB36:PDXB_VIBVU Erythronate-4-phosphate dehydrogenase - Vibrio vulnificus| Length = 377 Score = 85.1 bits (209), Expect = 7e-16 Identities = 55/161 (34%), Positives = 88/161 (54%), Gaps = 4/161 (2%) Frame = +2 Query: 665 QTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWK 844 QTVG+IGAG++GS Y + ++G + ++ D F + G++ + Sbjct: 118 QTVGIIGAGQVGS-YLQQCLQGIGIKVLIND---------------PFKQEEGDE----R 157 Query: 845 RASSMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVA 1012 +S++ +L+EADVI+LH + + T+HLIN E L ++ + +L+NA+RGPV+D A Sbjct: 158 EFTSLDRLLQEADVITLHTPITRDGKYPTHHLINEEILNSLRADQILINAARGPVVDNQA 217 Query: 1013 LVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIA 1135 L L+ F LDVFE EP + L + A PH+A Sbjct: 218 LKRRLQQADGFMAALDVFEFEPEVDMELLPLL-AFATPHVA 257
>Q47748:VANH_ENTFA D-specific alpha-keto acid dehydrogenase - Enterococcus faecalis| (Streptococcus faecalis) Length = 323 Score = 84.7 bits (208), Expect = 1e-15 Identities = 75/288 (26%), Positives = 119/288 (41%), Gaps = 15/288 (5%) Frame = +2 Query: 317 LSVDDILALIGDHCHGVIGQLTEDWGEVLFSALKRAGGTAFSNMAVGYNNVDVDAANKNG 496 +S D+ G+ C V G +E E AL++ G S ++G N++D AA + G Sbjct: 38 ISADNAKLAAGNQCISV-GHKSEV-SEATILALRKVGVKYISTRSIGCNHIDTTAAERMG 95 Query: 497 IAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLPHLFVGNLLKGQTVG 676 I++G + + I A + A + G L+ TVG Sbjct: 96 ISVGT----VAYSPDSVADYALMLMLMAIRGAKSTIHAVAQQNFRLDCVRGKELRDMTVG 151 Query: 677 VIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASS 856 VIG G IG A + + GF ++ +D K Y Q Sbjct: 152 VIGTGHIGQAVVKRL-RGFGCRVLAYD-----NSRKIEADYVQ----------------- 188 Query: 857 MEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKAN 1036 ++E+L+ +D+++LH L T HLI ++ MK+ A L+N RG ++D +LVE L + Sbjct: 189 LDELLKNSDIVTLHVPLCADTRHLIGQRQIGEMKQGAFLINTGRGALVDTGSLVEALGSG 248 Query: 1037 PMFRVGLDVFE---------------DEPYMKPGLAEMKNAVVVPHIA 1135 + LDV E D P++ L M N ++ PH A Sbjct: 249 KLGGAALDVLEGEDQFVYTDCSQKVLDHPFLSQ-LLRMPNVIITPHTA 295
>Q7MIT6:PDXB_VIBVY Erythronate-4-phosphate dehydrogenase - Vibrio vulnificus (strain| YJ016) Length = 377 Score = 84.7 bits (208), Expect = 1e-15 Identities = 54/161 (33%), Positives = 88/161 (54%), Gaps = 4/161 (2%) Frame = +2 Query: 665 QTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWK 844 QTVG++GAG++GS Y + ++G + ++ D F + G++ + Sbjct: 118 QTVGIVGAGQVGS-YLQQCLQGIGIKVLIND---------------PFKQEEGDE----R 157 Query: 845 RASSMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVA 1012 +S++ +L+EADVI+LH + + T+HLIN E L ++ + +L+NA+RGPV+D A Sbjct: 158 EFTSLDRLLQEADVITLHTPITRDGKYPTHHLINKEILNSLRADQILINAARGPVVDNQA 217 Query: 1013 LVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIA 1135 L L+ F LDVFE EP + L + A PH+A Sbjct: 218 LKHRLQQADGFTAALDVFEFEPEVDMELLPLL-AFATPHVA 257
>Q8E0N5:LDHD_STRA5 D-lactate dehydrogenase - Streptococcus agalactiae serotype V| Length = 330 Score = 84.7 bits (208), Expect = 1e-15 Identities = 62/242 (25%), Positives = 108/242 (44%), Gaps = 1/242 (0%) Frame = +2 Query: 362 GVIGQLTEDWGEVLFSALKRAGGTAFSNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTX 541 G+ E + ++ LK G + + G + +++ A ++GI I N P E+ Sbjct: 47 GIANAQIEPLDDAIYPLLKEMGIKQIAQRSAGVDMYNLELAKQHGIIISNVPSYSPESIA 106 Query: 542 XXXXXXXXXXXRRIVEADQFMRAGLYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMM 721 R++ +R + LP G +L TV +IG GRIG A A++ Sbjct: 107 EFTVTIALNLIRKVELIRANVREQNFSWTLP--IRGRVLGNMTVAIIGTGRIGLATAKIF 164 Query: 722 IEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLHP 901 +GF +I +D+Y + + + + +S+EE + EAD++SLH Sbjct: 165 -KGFGCRVIGYDIYHNPMADGIL-----------------EYVNSVEEAVEEADLVSLHM 206 Query: 902 VLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDE-P 1078 HL N + KK A+L+N +RG +++ L+E L + G+D +E E P Sbjct: 207 PPTAENTHLFNLDMFKQFKKGAILMNMARGALVETKDLLEALDQGLLEGAGIDTYEFEGP 266 Query: 1079 YM 1084 Y+ Sbjct: 267 YI 268
>P40510:SER33_YEAST D-3-phosphoglycerate dehydrogenase 2 - Saccharomyces cerevisiae| (Baker's yeast) Length = 469 Score = 84.3 bits (207), Expect = 1e-15 Identities = 77/315 (24%), Positives = 144/315 (45%), Gaps = 18/315 (5%) Frame = +2 Query: 257 IKLLTDNDCRLEICTEKKTILSVDDILALIGD-HCHGVIGQ--LTEDWGEVLFSALKRAG 427 IK+ D ++E K+ L D+++ I D H G+ + LTE L+ A Sbjct: 72 IKIFKDQGYQVEF---HKSSLPEDELIEKIKDVHAIGIRSKTRLTE-------KILQHAR 121 Query: 428 G-TAFSNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFM 604 +G N VD+ A GIA+ N+P + + R++ + + Sbjct: 122 NLVCIGCFCIGTNQVDLKYAASKGIAVFNSPFSNSRSVAELVIGEIISLARQLGDRSIEL 181 Query: 605 RAGLYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEK 784 G ++ + ++G+T+G+IG G IGS + ++ E ++++Y+D+ Sbjct: 182 HTGTWNKVAARCWE---VRGKTLGIIGYGHIGSQLS-VLAEAMGLHVLYYDIVT------ 231 Query: 785 FVTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKE 964 + A G T ++ S+++E+L ++D ++LH T +++ + A MK Sbjct: 232 -IMALG-----------TARQVSTLDELLNKSDFVTLHVPATPETEKMLSAPQFAAMKDG 279 Query: 965 AVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPG--------------LAE 1102 A ++NASRG V+D +L++ +KAN + LDV+ EP K G L Sbjct: 280 AYVINASRGTVVDIPSLIQAVKANKIAGAALDVYPHEP-AKNGEGSFNDELNSWTSELVS 338 Query: 1103 MKNAVVVPHIASASK 1147 + N ++ PHI +++ Sbjct: 339 LPNIILTPHIGGSTE 353
>P17584:DHD2_LACPA D-2-hydroxyisocaproate dehydrogenase - Lactobacillus paracasei| Length = 333 Score = 84.3 bits (207), Expect = 1e-15 Identities = 73/273 (26%), Positives = 120/273 (43%), Gaps = 15/273 (5%) Frame = +2 Query: 362 GVIGQLTEDWGEVLFSALKRAGGTAFSNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTX 541 G+ T + +F + G + VG +N+D+ A + GI + N P Sbjct: 47 GINSLQTTPYAAGVFEKMHAYGIKFLTIRNVGTDNIDMTAMKQYGIRLSNVPAYSPAAIA 106 Query: 542 XXXXXXXXXXXRRIVEADQFMRAGLYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMM 721 R + + ++AG Y+ F+G L QTVGV+G G IG A + Sbjct: 107 EFALTDTLYLLRNMGKVQAQLQAGDYEK--AGTFIGKELGQQTVGVMGTGHIGQV-AIKL 163 Query: 722 IEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLH- 898 +GF +I +D Y G+ P S+E++ +++DVI LH Sbjct: 164 FKGFGAKVIAYDPYPM----------------KGDHPDF--DYVSLEDLFKQSDVIDLHV 205 Query: 899 PVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEP 1078 P +++ T H+IN +MK A+++N +R +ID A++ +LK+ + VG+D +E E Sbjct: 206 PGIEQNT-HIINEAAFNLMKPGAIVINTARPNLIDTQAMLSNLKSGKLAGVGIDTYEYET 264 Query: 1079 YMKPGLAE--------------MKNAVVVPHIA 1135 LA+ M N V+ PHIA Sbjct: 265 EDLLNLAKHGSFKDPLWDELLGMPNVVLSPHIA 297
>Q99ZM2:LDHD_STRP1 D-lactate dehydrogenase - Streptococcus pyogenes serotype M1| Length = 330 Score = 83.6 bits (205), Expect = 2e-15 Identities = 64/231 (27%), Positives = 106/231 (45%), Gaps = 1/231 (0%) Frame = +2 Query: 395 EVLFSALKRAGGTAFSNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXX 574 + ++ LK G + + + ++D A +N I I N P E+ Sbjct: 58 DAIYPLLKEMGIKQIAQHSASVDMYNLDLATENDIIITNVPSYSPESIAEFTVTIVLNLI 117 Query: 575 RRIVEADQFMRAGLYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYF 754 R + + ++ + LP G +L TV +IG GRIG A A++ +GF ++ + Sbjct: 118 RHVELIRENVKKQNFTWGLP--IRGRVLGDMTVAIIGTGRIGLATAKIF-KGFGCKVVGY 174 Query: 755 DLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLIN 934 D+YQS K V Y + S+EE +++AD++SLH HL N Sbjct: 175 DIYQSDAA-KAVLDYKE----------------SVEEAIKDADLVSLHMPPTAENTHLFN 217 Query: 935 PERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDE-PYM 1084 + KK A+L+N +RG VI+ L++ L A + G+D +E E PY+ Sbjct: 218 SDLFKSFKKGAILMNMARGAVIETQDLLDALDAGLLSGAGIDTYEFEGPYI 268
>Q05709:VANH_ENTFC D-specific alpha-keto acid dehydrogenase - Enterococcus faecium| (Streptococcus faecium) Length = 322 Score = 82.4 bits (202), Expect = 5e-15 Identities = 74/275 (26%), Positives = 118/275 (42%), Gaps = 19/275 (6%) Frame = +2 Query: 368 IGQLTEDWGEVLFSALKRAGGTAFSNMAVGYNNVDVDAANKNGIAIGN---TPGVLTETT 538 +G +E +L ALKRAG S ++G N++D AA + GI + N +P + + T Sbjct: 53 VGHKSEISASILL-ALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAYSPDSVADYT 111 Query: 539 XXXXXXXXXXXXR--RIVEADQFMRAGLYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAYA 712 R VE F G +L TVGV+G G+IG A Sbjct: 112 MMLILMAVRNVKSIVRSVEKHDFRLDS---------DRGKVLSDMTVGVVGTGQIGKAVI 162 Query: 713 RMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADVIS 892 + GF ++ + +S + Y F +E+L+ +D+++ Sbjct: 163 E-RLRGFGCKVLAYSRSRSIEVN-----YVPF-----------------DELLQNSDIVT 199 Query: 893 LHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFED 1072 LH L+ T+++I+ E++ MK+ A L+N RGP++D LV+ L+ + LDV E Sbjct: 200 LHVPLNTDTHYIISHEQIQRMKQGAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEG 259 Query: 1073 EP-------YMKP-------GLAEMKNAVVVPHIA 1135 E KP L M N ++ PH A Sbjct: 260 EEEFFYSDCTQKPIDNQFLLKLQRMPNVIITPHTA 294
>Q7N2B2:PDXB_PHOLL Erythronate-4-phosphate dehydrogenase - Photorhabdus luminescens| subsp. laumondii Length = 375 Score = 81.3 bits (199), Expect = 1e-14 Identities = 59/176 (33%), Positives = 94/176 (53%), Gaps = 5/176 (2%) Frame = +2 Query: 656 LKGQTVGVIGAGRIGSAYA-RMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQP 832 LK + VG++G G +GS A R+ + G + L R ++ G+ Sbjct: 114 LKDKVVGIVGVGNVGSRLAERLAVLGIRTLLC-----DPPRADR------------GDAG 156 Query: 833 VTWKRASSMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVI 1000 W S+E++++EAD+++ H L+K+ T+HL++ E L+++ +L+NASRG VI Sbjct: 157 EFW----SLEKLVKEADILTFHTPLNKSGPYKTHHLVDVELLSVLPDNRILINASRGEVI 212 Query: 1001 DEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA 1168 D AL+ LK RV LDV+E EP + L E+ + + PHIA +T EG A Sbjct: 213 DNQALLTALKCGKKLRVVLDVWEPEPDLSLPLLELVD-IGTPHIAG---YTLEGKA 264
>Q8E6A9:LDHD_STRA3 D-lactate dehydrogenase - Streptococcus agalactiae serotype III| Length = 330 Score = 81.3 bits (199), Expect = 1e-14 Identities = 59/231 (25%), Positives = 105/231 (45%), Gaps = 1/231 (0%) Frame = +2 Query: 395 EVLFSALKRAGGTAFSNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXX 574 + ++ LK G + + G + +++ A ++GI I N P E+ Sbjct: 58 DAIYPLLKEMGIKQIAQRSAGVDMYNLELAKQHGIIISNVPSYSPESIAEFTVTIALNLI 117 Query: 575 RRIVEADQFMRAGLYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYF 754 R++ +R + LP G +L TV +IG GRIG A A++ +GF +I + Sbjct: 118 RKVELIRANVREQNFSWTLP--IRGRVLGNMTVAIIGTGRIGLATAKIF-KGFGCRVIGY 174 Query: 755 DLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLIN 934 D+Y + + + + +S+EE + +AD++SLH HL N Sbjct: 175 DIYHNPMADGIL-----------------EYVNSVEEAVEKADLVSLHMPPTAENTHLFN 217 Query: 935 PERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDE-PYM 1084 + KK A+L+N +RG +++ L+E L + G+D +E E PY+ Sbjct: 218 LDMFKQFKKGAILMNMARGALVETKDLLEALDQGLLEGAGIDTYEFEGPYI 268
>Q88VJ2:LDHD_LACPL D-lactate dehydrogenase - Lactobacillus plantarum| Length = 332 Score = 80.5 bits (197), Expect = 2e-14 Identities = 65/238 (27%), Positives = 106/238 (44%), Gaps = 7/238 (2%) Frame = +2 Query: 383 EDWGEVLFSALKRAGGTAFSNMAVGYNNVDVDAANKNGIAIGNTPGV-------LTETTX 541 +D+ + + L G S VG +N+DV G+ I N P L+ T Sbjct: 55 KDYTAEVLNKLADEGVKNISLRNVGVDNLDVPTVKARGLNISNVPAYSPNAIAELSVTQL 114 Query: 542 XXXXXXXXXXXRRIVEADQFMRAGLYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMM 721 +++ + D W P + L TVGVIG GRIG A A + Sbjct: 115 MQLLRQTPLFNKKLAKQDF--------RWAPD--IAKELNTMTVGVIGTGRIGRA-AIDI 163 Query: 722 IEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLHP 901 +GF +I +D+Y++ LEK G ++ +++E+ +ADVI+LH Sbjct: 164 FKGFGAKVIGYDVYRNAELEK----EGMYV-------------DTLDELYAQADVITLHV 206 Query: 902 VLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDE 1075 K YH++N + + MK A ++N +RG +ID L++ L + + LD +E E Sbjct: 207 PALKDNYHMLNADAFSKMKDGAYILNFARGTLIDSEDLIKALDSGKVAGAALDTYEYE 264
>Q9KQ92:PDXB_VIBCH Erythronate-4-phosphate dehydrogenase - Vibrio cholerae| Length = 381 Score = 78.6 bits (192), Expect = 7e-14 Identities = 62/199 (31%), Positives = 98/199 (49%), Gaps = 6/199 (3%) Frame = +2 Query: 665 QTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWK 844 +TVG+IGAG++GS Y + G M ++ D + +A G++ + Sbjct: 118 KTVGIIGAGQVGS-YLAKCLSGIGMKVLLNDPPK---------------QAQGDE----R 157 Query: 845 RASSMEEVLREADVISLHPVLDK----TTYHLINPERLAMMKKEAVLVNASRGPVIDEVA 1012 + +E +L++ADVI+LH + + T+HLI+ L ++ + +L+NA+RGPV+D A Sbjct: 158 EFTELETLLKQADVITLHTPITRGGEWPTHHLIDAAILEQLRSDQILINAARGPVVDNAA 217 Query: 1013 LVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA--TLAALN 1186 L L+ F LDVFE EP + L + A PHIA + EG A T N Sbjct: 218 LKARLQQGDGFTAVLDVFEFEPQVDMELLPLL-AFATPHIAG---YGLEGKARGTTMIFN 273 Query: 1187 VLGKIKGYPVWGNPNAVEP 1243 + G NP ++ P Sbjct: 274 SYCEFLGSAHCANPASLLP 292
>P26298:LDHD_LACPE D-lactate dehydrogenase - Lactobacillus pentosus| Length = 332 Score = 77.0 bits (188), Expect = 2e-13 Identities = 62/231 (26%), Positives = 103/231 (44%) Frame = +2 Query: 383 EDWGEVLFSALKRAGGTAFSNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXX 562 +D+ + + L G S VG +N+DV G+ I N P Sbjct: 55 KDYTAEVLNKLADEGVKNISLRNVGVDNLDVPTVKARGLNISNVPAYSPNAIAELSVTQL 114 Query: 563 XXXXRRIVEADQFMRAGLYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMN 742 R+ ++ + + W P + L TVGVIG GRIG A A + +GF Sbjct: 115 MQLLRQTPMFNKKLAKQDFR-WAPD--IAKELNTMTVGVIGTGRIGRA-AIDIFKGFGAK 170 Query: 743 LIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTY 922 +I +D+Y++ LEK G ++ +++E+ +ADVI+LH K Y Sbjct: 171 VIGYDVYRNAELEK----EGMYV-------------DTLDELYAQADVITLHVPALKDNY 213 Query: 923 HLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDE 1075 H++N + + MK A ++N +RG +ID L++ L + + L +E E Sbjct: 214 HMLNADAFSKMKDGAYILNFARGTLIDSEDLIKALDSGKVAGAALVTYEYE 264
>Q07103:FDH_NEUCR Formate dehydrogenase - Neurospora crassa| Length = 375 Score = 77.0 bits (188), Expect = 2e-13 Identities = 66/240 (27%), Positives = 111/240 (46%), Gaps = 9/240 (3%) Frame = +2 Query: 452 VGYNNVDVDAANKN--GIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDG 625 +G ++VD++AANK GI + G + R V A + ++ G +D Sbjct: 94 IGSDHVDLNAANKTNGGITVAEVTGSNVVSVAEHVLMTILVLVRNFVPAHEQIQEGRWD- 152 Query: 626 WLPHLFVGNL-LKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYG 802 + L+G+ VG +G GRIG R + L+Y+D YQ EK Sbjct: 153 -VAEAAKNEFDLEGKVVGTVGVGRIGERVLRRLKPFDCKELLYYD-YQPLSAEK------ 204 Query: 803 QFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNA 982 E + +R + +EE+L + DV++++ L + T L N E ++ MKK + LVN Sbjct: 205 -------EAEIGCRRVADLEEMLAQCDVVTINCPLHEKTQGLFNKELISKMKKGSWLVNT 257 Query: 983 SRGPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKP-GLAEMKNA-----VVVPHIASAS 1144 +RG ++ + + E LK+ + G DV+ +P + L KN +VPH++ S Sbjct: 258 ARGAIVVKEDVAEALKSGHLRGYGGDVWFPQPAPQDHPLRYAKNPFGGGNAMVPHMSGTS 317
>Q9I3W9:PDXB_PSEAE Erythronate-4-phosphate dehydrogenase - Pseudomonas aeruginosa| Length = 380 Score = 75.5 bits (184), Expect = 6e-13 Identities = 58/167 (34%), Positives = 82/167 (49%), Gaps = 4/167 (2%) Frame = +2 Query: 656 LKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPV 835 L +T GV+GAG++G ++ G ++ D + R G+F+ Sbjct: 114 LAERTYGVVGAGQVGGRLVEVL-RGLGWKVLVCDPPRQAREPD-----GEFV-------- 159 Query: 836 TWKRASSMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVID 1003 S+E +L EADVISLH L++ T HL++ RLA ++ LVNASRG V+D Sbjct: 160 ------SLERLLAEADVISLHTPLNRDGEHPTRHLLDEPRLAALRPGTWLVNASRGAVVD 213 Query: 1004 EVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASAS 1144 AL L+ V LDV+E EP P LA + + PHIA S Sbjct: 214 NQALRRLLEGGADLEVALDVWEGEPQADPELA-ARCLIATPHIAGYS 259
>Q87MN8:PDXB_VIBPA Erythronate-4-phosphate dehydrogenase - Vibrio parahaemolyticus| Length = 377 Score = 75.1 bits (183), Expect = 8e-13 Identities = 50/161 (31%), Positives = 85/161 (52%), Gaps = 4/161 (2%) Frame = +2 Query: 665 QTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWK 844 +TVG+IGAG++GS Y ++G +N++ D + K P ++ Sbjct: 118 KTVGIIGAGQVGS-YLEKCLKGMGINVLINDPF----------------KQEAGDPRSF- 159 Query: 845 RASSMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVA 1012 + + E++ ++D+I+LH + K T+HLI+ + L ++ + +L+NA+RGPV+D A Sbjct: 160 --TPLAELIEQSDIITLHTPITKDGLHPTHHLIDEKVLNGLRGDQILINAARGPVVDNQA 217 Query: 1013 LVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIA 1135 L + L F LDVFE EP + L + A PH+A Sbjct: 218 LKQRLMKQDGFTAALDVFEFEPEVDMELLPLL-AFATPHVA 257
>Q8ECR2:PDXB_SHEON Erythronate-4-phosphate dehydrogenase - Shewanella oneidensis| Length = 376 Score = 73.6 bits (179), Expect = 2e-12 Identities = 55/167 (32%), Positives = 83/167 (49%), Gaps = 4/167 (2%) Frame = +2 Query: 656 LKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPV 835 L+G+ VG++GAG GSA A+ + E F + ++ D + +A G+ Sbjct: 115 LRGKVVGIVGAGNTGSATAKCL-EAFGIKVLLNDPIK---------------EAEGDP-- 156 Query: 836 TWKRASSMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVID 1003 + S+E +L+EAD+ISLH + +T T HL + RL +K L+N RG VID Sbjct: 157 --RDFVSLETLLQEADIISLHVPITRTGEHKTLHLFDEARLMSLKANIWLINCCRGDVID 214 Query: 1004 EVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASAS 1144 AL++ + ++ LDV+E EP P L PHIA S Sbjct: 215 NQALIKVKQQRDDLKLVLDVWEGEPNPMPELVPFAE-FATPHIAGYS 260
>Q884R9:PDXB_PSESM Erythronate-4-phosphate dehydrogenase - Pseudomonas syringae pv.| tomato Length = 380 Score = 73.6 bits (179), Expect = 2e-12 Identities = 57/168 (33%), Positives = 87/168 (51%), Gaps = 5/168 (2%) Frame = +2 Query: 656 LKGQTVGVIGAGRIGSAY-ARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQP 832 L+ +T GV+GAG++G A + G+K+ L+ QS FV Sbjct: 114 LRQRTYGVVGAGQVGGRLIAVLKALGWKV-LVCDPPRQSAEGGDFV-------------- 158 Query: 833 VTWKRASSMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVI 1000 S++E+L+ DVISLH LDK+ T+HL++ RL +++ A L+NASRG V+ Sbjct: 159 -------SLDEILQRCDVISLHTPLDKSGQSPTWHLLDEARLRQLRQGAWLINASRGAVV 211 Query: 1001 DEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASAS 1144 D AL + + + LDV+E EP + LA++ + PHIA S Sbjct: 212 DNRALHDVMLEREDLQAVLDVWEGEPQVNVALADL-CVIGTPHIAGYS 258
>Q88L20:PDXB_PSEPK Erythronate-4-phosphate dehydrogenase - Pseudomonas putida (strain| KT2440) Length = 380 Score = 73.6 bits (179), Expect = 2e-12 Identities = 59/171 (34%), Positives = 85/171 (49%), Gaps = 5/171 (2%) Frame = +2 Query: 647 GNLLKGQTVGVIGAGRIGSAYARMMIE-GFKMNLIYFDLYQSTRLEKFVTAYGQFLKANG 823 G L + GV+GAG +G R++ G+K+ L+ L Q+ +V Sbjct: 111 GVALPERVYGVVGAGEVGGRLVRVLHGLGWKV-LVCDPLRQAAEGGDYV----------- 158 Query: 824 EQPVTWKRASSMEEVLREADVISLHPVLDK----TTYHLINPERLAMMKKEAVLVNASRG 991 S+E +L++ DVISLH L + T+HL+ +LA ++ A LVNASRG Sbjct: 159 ----------SLETILQQCDVISLHTPLQRGGQHPTWHLLGQAQLAQLRPGAWLVNASRG 208 Query: 992 PVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASAS 1144 PV+D VAL E L LDV+E EP + LA++ + PHIA S Sbjct: 209 PVVDNVALRELLLDREDVHAVLDVWEGEPQVDLQLADL-CTLATPHIAGYS 258
>Q668W7:PDXB_YERPS Erythronate-4-phosphate dehydrogenase - Yersinia pseudotuberculosis| Length = 375 Score = 71.2 bits (173), Expect = 1e-11 Identities = 59/180 (32%), Positives = 89/180 (49%), Gaps = 6/180 (3%) Frame = +2 Query: 647 GNLLKGQTVGVIGAGRIGSAY-ARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANG 823 G L+ +TVG+IG G +GS AR+ G + L R ++ G Sbjct: 111 GFQLRDKTVGIIGVGNVGSRLNARLQALGVRTLLC-----DPPRADR------------G 153 Query: 824 EQPVTWKRASSMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRG 991 + W +E+++READV++ H L+KT + H+ + E LA + +L+NA RG Sbjct: 154 DNEAFWP----LEKLVREADVLTFHTPLNKTGAYQSLHMADDELLAALPDGRILINACRG 209 Query: 992 PVIDEVALVEHLKANPMFRVGLDVFEDEPYMK-PGLAEMKNAVVVPHIASASKWTREGMA 1168 V+D AL+ L+ V LDV+E EP + P LA + + PHIA +T EG A Sbjct: 210 AVVDNAALLRALEKGKKLSVVLDVWEPEPDLSLPLLARVD--IGTPHIAG---YTLEGKA 264
>Q8D0U3:PDXB_YERPE Erythronate-4-phosphate dehydrogenase - Yersinia pestis| Length = 375 Score = 71.2 bits (173), Expect = 1e-11 Identities = 59/180 (32%), Positives = 89/180 (49%), Gaps = 6/180 (3%) Frame = +2 Query: 647 GNLLKGQTVGVIGAGRIGSAY-ARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANG 823 G L+ +TVG+IG G +GS AR+ G + L R ++ G Sbjct: 111 GFQLRDKTVGIIGVGNVGSRLNARLQALGVRTLLC-----DPPRADR------------G 153 Query: 824 EQPVTWKRASSMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRG 991 + W +E+++READV++ H L+KT + H+ + E LA + +L+NA RG Sbjct: 154 DNEAFWP----LEKLVREADVLTFHTPLNKTGAYQSLHMADDELLAALPDGRILINACRG 209 Query: 992 PVIDEVALVEHLKANPMFRVGLDVFEDEPYMK-PGLAEMKNAVVVPHIASASKWTREGMA 1168 V+D AL+ L+ V LDV+E EP + P LA + + PHIA +T EG A Sbjct: 210 AVVDNAALLRALEKGKKLSVVLDVWEPEPDLSLPLLARVD--IGTPHIAG---YTLEGKA 264
>Q9SXP2:FDH1_ORYSJ Formate dehydrogenase 1, mitochondrial precursor - Oryza sativa| subsp. japonica (Rice) Length = 376 Score = 71.2 bits (173), Expect = 1e-11 Identities = 61/233 (26%), Positives = 105/233 (45%), Gaps = 2/233 (0%) Frame = +2 Query: 452 VGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWL 631 +G +++D+ AA G+ + G T + R + Q + G ++ Sbjct: 120 IGSDHIDLPAAAAAGLTVAEVTGSNTVSVAEDELMRILILLRNFLPGYQQVVHGEWNV-A 178 Query: 632 PHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFD-LYQSTRLEKFVTAYGQF 808 + L+G+TVG +GAGRIG + + + F NL+Y D L LEK + A Sbjct: 179 GIAYRAYDLEGKTVGTVGAGRIGRLLLQRL-KPFNCNLLYHDRLKIDPELEKEIGA---- 233 Query: 809 LKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASR 988 K ++ +L + DVI ++ L + T + N ER+A MKK ++VN +R Sbjct: 234 -----------KYEEDLDAMLPKCDVIVINTPLTEKTRGMFNKERIAKMKKGVIIVNNAR 282 Query: 989 GPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKP-GLAEMKNAVVVPHIASAS 1144 G ++D A+ + + + G DV+ +P K M N + PHI+ + Sbjct: 283 GAIMDTQAVADACSSGQVAGYGGDVWFPQPAPKDHPWRYMPNHAMTPHISGTT 335
>P60802:PDXB_SALTY Erythronate-4-phosphate dehydrogenase - Salmonella typhimurium| Length = 378 Score = 70.9 bits (172), Expect = 1e-11 Identities = 54/178 (30%), Positives = 88/178 (49%), Gaps = 4/178 (2%) Frame = +2 Query: 647 GNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGE 826 G L+ +T+G++G G +GS + +E + + D ++ R ++ G F Sbjct: 111 GFSLRDRTIGIVGVGNVGSRL-QTRLEALGIRTLLCDPPRAARGDE-----GDF------ 158 Query: 827 QPVTWKRASSMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGP 994 +++E+++EADV++ H L K T HL + + +K A+L+NA RGP Sbjct: 159 --------RTLDELVQEADVLTFHTPLYKDGPYKTLHLADETLIRRLKPGAILINACRGP 210 Query: 995 VIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA 1168 V+D AL+ L A V LDV+E EP + L E + + HIA +T EG A Sbjct: 211 VVDNAALLARLNAGQPLSVVLDVWEGEPDLNVALLEAVD-IGTSHIAG---YTLEGKA 264
>P60801:PDXB_SALTI Erythronate-4-phosphate dehydrogenase - Salmonella typhi| Length = 378 Score = 70.9 bits (172), Expect = 1e-11 Identities = 54/178 (30%), Positives = 88/178 (49%), Gaps = 4/178 (2%) Frame = +2 Query: 647 GNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGE 826 G L+ +T+G++G G +GS + +E + + D ++ R ++ G F Sbjct: 111 GFSLRDRTIGIVGVGNVGSRL-QTRLEALGIRTLLCDPPRAARGDE-----GDF------ 158 Query: 827 QPVTWKRASSMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGP 994 +++E+++EADV++ H L K T HL + + +K A+L+NA RGP Sbjct: 159 --------RTLDELVQEADVLTFHTPLYKDGPYKTLHLADETLIRRLKPGAILINACRGP 210 Query: 995 VIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA 1168 V+D AL+ L A V LDV+E EP + L E + + HIA +T EG A Sbjct: 211 VVDNAALLARLNAGQPLSVVLDVWEGEPDLNVALLEAVD-IGTSHIAG---YTLEGKA 264
>Q9ZRI8:FDH_HORVU Formate dehydrogenase, mitochondrial precursor - Hordeum vulgare| (Barley) Length = 377 Score = 70.5 bits (171), Expect = 2e-11 Identities = 59/234 (25%), Positives = 106/234 (45%), Gaps = 3/234 (1%) Frame = +2 Query: 452 VGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYD-GW 628 +G +++D+ AA G+ + G T + R + Q + G ++ Sbjct: 121 IGSDHIDLPAAAAAGLTVARVTGSNTVSVAEDELMRILILLRNFLPGYQQVVKGEWNVAG 180 Query: 629 LPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQ-STRLEKFVTAYGQ 805 + H L+G+TVG +GAGR G + + + F NL+Y D Q + LEK + A Sbjct: 181 IAHRAYD--LEGKTVGTVGAGRYGRLLLQRL-KPFNCNLLYHDRLQINPELEKEIGA--- 234 Query: 806 FLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNAS 985 K ++ +L + DV+ ++ L + T + N E++A MKK ++VN + Sbjct: 235 ------------KFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGVIIVNNA 282 Query: 986 RGPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKP-GLAEMKNAVVVPHIASAS 1144 RG ++D A+ + + + G DV+ +P K M N + PHI+ + Sbjct: 283 RGAIMDTQAVADACSSGHIAGYGGDVWFPQPAPKDHPWRYMPNHAMTPHISGTT 336
>Q8D2P6:PDXB_WIGBR Erythronate-4-phosphate dehydrogenase - Wigglesworthia glossinidia| brevipalpis Length = 378 Score = 68.2 bits (165), Expect = 9e-11 Identities = 68/249 (27%), Positives = 106/249 (42%), Gaps = 5/249 (2%) Frame = +2 Query: 413 LKRAGGTAFSNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEA 592 LK + + G ++VDVD KN I PG + A Sbjct: 54 LKNSNIKFIGSATSGKDHVDVDWLKKNKINFDFAPGC-----------------NSVAVA 96 Query: 593 DQFMRAGLYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIE-GFKMNLIYFDLYQS 769 + + LY + +LLK +TVG++G G IG + + G K L L + Sbjct: 97 EYVFSSMLYFAYRDKF---SLLK-KTVGIVGFGNIGKCLNKKLSAIGVKTILCDPILEEK 152 Query: 770 TRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKT----TYHLINP 937 + + S+ E+++ +D+I+LH L + T+HLIN Sbjct: 153 NNI----------------------KLKSLNEIVQNSDIITLHVPLTYSGKYPTWHLINK 190 Query: 938 ERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAV 1117 + L +K +L+N SRG VID +L+ LK RV LDV+E+EP + L + + + Sbjct: 191 KILLDLKDNCILINTSRGSVIDNNSLLNILKEGKPIRVVLDVWENEPLICSKLLSLID-I 249 Query: 1118 VVPHIASAS 1144 PHIA S Sbjct: 250 GTPHIAGHS 258
>Q56733:PDXB_SHEVI Erythronate-4-phosphate dehydrogenase - Shewanella violacea| Length = 274 Score = 67.8 bits (164), Expect = 1e-10 Identities = 52/167 (31%), Positives = 80/167 (47%), Gaps = 4/167 (2%) Frame = +2 Query: 656 LKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPV 835 LK +TVG++GAG GSA A+ + L++ + Q + F+ Sbjct: 2 LKDKTVGIVGAGNTGSAVAKCLQAYGVTVLLHDPVIQDSDPRDFI--------------- 46 Query: 836 TWKRASSMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVID 1003 S++E++ DVISLH + KT T++L + RL +K L+N RG VID Sbjct: 47 ------SLDELIARCDVISLHVPIIKTGEHKTWYLFDETRLNSLKPGTWLLNCCRGEVID 100 Query: 1004 EVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASAS 1144 AL++ + P ++ LDV+E EP L + + PHIA S Sbjct: 101 NRALIKVKQQRPDIKLVLDVWEGEPNPMHELIPLVE-LATPHIAGYS 146
>Q07511:FDH_SOLTU Formate dehydrogenase, mitochondrial precursor - Solanum tuberosum| (Potato) Length = 381 Score = 67.4 bits (163), Expect = 2e-10 Identities = 57/234 (24%), Positives = 106/234 (45%), Gaps = 3/234 (1%) Frame = +2 Query: 452 VGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYD-GW 628 +G ++VD+ AA G+ + G T + R + + G ++ Sbjct: 125 IGSDHVDLKAAAAAGLTVAEVTGSNTVSVAEDELMRILILVRNFLPGHHQVINGEWNVAA 184 Query: 629 LPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFD-LYQSTRLEKFVTAYGQ 805 + H L+G+TVG +GAGRIG + + + F NL+Y D L + LE + A Sbjct: 185 IAHRAYD--LEGKTVGTVGAGRIGRLLLQRL-KPFNCNLLYHDRLKMDSELENQIGA--- 238 Query: 806 FLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNAS 985 K ++++L + D++ ++ L + T + + ER+A +KK ++VN + Sbjct: 239 ------------KFEEDLDKMLSKCDIVVINTPLTEKTKGMFDKERIAKLKKGVLIVNNA 286 Query: 986 RGPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKP-GLAEMKNAVVVPHIASAS 1144 RG ++D A+V+ + + DV+ +P K M N + PHI+ + Sbjct: 287 RGAIMDTQAVVDACNSGHIAGYSGDVWYPQPAPKDHPWRYMPNQAMTPHISGTT 340
>Q56731:PDXB_SHESP Erythronate-4-phosphate dehydrogenase - Shewanella sp. (strain| DB6705) Length = 274 Score = 67.0 bits (162), Expect = 2e-10 Identities = 52/167 (31%), Positives = 80/167 (47%), Gaps = 4/167 (2%) Frame = +2 Query: 656 LKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPV 835 LK +TVG++GAG GSA A+ + L++ + Q + F+ Sbjct: 2 LKDKTVGIVGAGNTGSAVAKCLQAYGVTVLLHDPVIQDSDPRDFI--------------- 46 Query: 836 TWKRASSMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVID 1003 S++E++ DVISLH + KT T++L + RL +K+ L+N RG VID Sbjct: 47 ------SLDELIACCDVISLHVPITKTGEHKTWYLFDEARLNSLKQGTWLLNCCRGEVID 100 Query: 1004 EVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASAS 1144 AL++ P ++ LDV+E EP L + + PHIA S Sbjct: 101 NQALIKVKLERPDIKLVLDVWEGEPNPMHELIPLVE-LATPHIAGYS 146
>Q8A2E4:PDXB_BACTN Erythronate-4-phosphate dehydrogenase - Bacteroides thetaiotaomicron| Length = 348 Score = 67.0 bits (162), Expect = 2e-10 Identities = 64/226 (28%), Positives = 97/226 (42%), Gaps = 15/226 (6%) Frame = +2 Query: 668 TVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKR 847 T+G+IG G +GS A++ + F M ++ DL R EK E +T+ Sbjct: 119 TIGIIGVGNVGSKVAKVA-QDFGMRVLLNDL---PREEK-------------EGNITF-- 159 Query: 848 ASSMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVAL 1015 +S+E++ E D+I+ H L K TYHL + ++++ V++N SRG VI+ AL Sbjct: 160 -TSLEKIAEECDIITFHVPLYKEGKYKTYHLADGNFFRSLQRKPVVINTSRGEVIETNAL 218 Query: 1016 VEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLG 1195 +E + + +DV+E EP + L E K + PHIA Sbjct: 219 LEAINNGIISDAVIDVWEHEPEINRELLE-KVLIGTPHIA-------------------- 257 Query: 1196 KIKGYPVWGNPNAVEPFLDE-----------EATPPPACPSIVNAK 1300 GY G NA LD E TPP ++ AK Sbjct: 258 ---GYSADGKANATRMSLDSICRFFHLSATYEITPPAPSSPLIEAK 300
>Q67U69:FDH2_ORYSJ Formate dehydrogenase 2, mitochondrial precursor - Oryza sativa| subsp. japonica (Rice) Length = 378 Score = 66.2 bits (160), Expect = 4e-10 Identities = 59/234 (25%), Positives = 103/234 (44%), Gaps = 3/234 (1%) Frame = +2 Query: 452 VGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYD-GW 628 VG +++D+ AA G+ + G T + R + + G ++ Sbjct: 122 VGSDHIDLPAAAAAGLTVAEITGSNTVSVAEDQLMRILLLLRNFLPGHHQIVNGEWNVAG 181 Query: 629 LPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQ-STRLEKFVTAYGQ 805 + H L+G+TVG +GAGRIG + + + F NL+Y D + LEK + A Sbjct: 182 IAHRTYD--LEGKTVGTVGAGRIGRLLLQRL-KPFNCNLMYHDRVKIDPELEKEIGA--- 235 Query: 806 FLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNAS 985 K ++ +L + DV+ ++ L + T + N ER+A MKK +VN + Sbjct: 236 ------------KYEEDLDAMLPKCDVVVINMPLTEKTRGMFNKERIAKMKKGVTIVNNA 283 Query: 986 RGPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKP-GLAEMKNAVVVPHIASAS 1144 RG ++D A+ + + + G DV+ +P K M N + PH + + Sbjct: 284 RGAIMDTQAVADACASGHVAGYGGDVWFPQPAPKDHPWRYMPNHAMTPHCSGTT 337
>P0C1E9:YPRB2_CORML Uncharacterized protein in proB 3'region - Corynebacterium| melassecola Length = 304 Score = 65.9 bits (159), Expect = 5e-10 Identities = 43/111 (38%), Positives = 55/111 (49%), Gaps = 1/111 (0%) Frame = +2 Query: 860 EEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANP 1039 E V EADV L L TY ++N E L MK AVLVN RGP+I+ LV+ L Sbjct: 175 EHVWAEADVFVLILPLTDATYQIVNAETLGKMKPSAVLVNVGRGPLINTDDLVDALNNGT 234 Query: 1040 MFRVGLDVFEDEPYM-KPGLAEMKNAVVVPHIASASKWTREGMATLAALNV 1189 + LDV + EP L EM N V+ PH A+ ++ R L N+ Sbjct: 235 IAGAALDVTDPEPLPDSHPLWEMDNVVITPHTANTNERIRALTGELTLRNI 285
>P0C1E8:Y2355_CORGL Uncharacterized protein Cgl2355/cg2587 - Corynebacterium glutamicum| (Brevibacterium flavum) Length = 304 Score = 64.7 bits (156), Expect = 1e-09 Identities = 42/111 (37%), Positives = 55/111 (49%), Gaps = 1/111 (0%) Frame = +2 Query: 860 EEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANP 1039 E V EADV L L TY ++N E L MK AV+VN RGP+I+ LV+ L Sbjct: 175 EHVWAEADVFVLILPLTDATYQIVNAETLGKMKPSAVVVNVGRGPLINTDDLVDALNNGT 234 Query: 1040 MFRVGLDVFEDEPYM-KPGLAEMKNAVVVPHIASASKWTREGMATLAALNV 1189 + LDV + EP L EM N V+ PH A+ ++ R L N+ Sbjct: 235 IAGAALDVTDPEPLPDSHPLWEMDNVVITPHTANTNERIRALTGELTLRNI 285
>Q6D2N5:PDXB_ERWCT Erythronate-4-phosphate dehydrogenase - Erwinia carotovora subsp.| atroseptica (Pectobacterium atrosepticum) Length = 378 Score = 64.3 bits (155), Expect = 1e-09 Identities = 73/273 (26%), Positives = 113/273 (41%), Gaps = 5/273 (1%) Frame = +2 Query: 365 VIGQLTEDWGEVLFSALKRAGGTAFSNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTXX 544 ++ +T+ +LF + + G+A G ++VD N NGIA PG Sbjct: 42 MVRSVTKVNANLLFGSSVKFVGSA----TAGTDHVDDTWLNANGIAFSAAPGC----NAI 93 Query: 545 XXXXXXXXXXRRIVEADQFMRAGLYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAY-ARMM 721 + E D F L+ +TVG++G G +G R+ Sbjct: 94 AVVEYVFSSLLMLAERDGFQ-----------------LRDKTVGIVGVGNVGRRLDTRLK 136 Query: 722 IEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLHP 901 G K L D ++ R + G FL S+E ++R+AD+++LH Sbjct: 137 AWGVKTLLC--DPPRADRGDA-----GDFL--------------SLETLVRDADILTLHT 175 Query: 902 VL----DKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFE 1069 L T+HL++ L +L+NA RGPV+D AL+E L+ V LDV+E Sbjct: 176 PLYLDGPYRTHHLVDATVLNAFADGRILINACRGPVVDNAALLEALQQGKKLSVILDVWE 235 Query: 1070 DEPYMKPGLAEMKNAVVVPHIASASKWTREGMA 1168 EP + L + + HIA +T EG A Sbjct: 236 PEPGLSTDLLARVD-IGTAHIAG---YTLEGKA 264
>Q03134:FDH_EMENI Probable formate dehydrogenase - Emericella nidulans (Aspergillus| nidulans) Length = 377 Score = 64.3 bits (155), Expect = 1e-09 Identities = 62/233 (26%), Positives = 99/233 (42%), Gaps = 21/233 (9%) Frame = +2 Query: 452 VGYNNVDVDAANKN--GIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDG 625 +G ++VD+DAANK GI + G + R V A +R G Sbjct: 89 IGSDHVDLDAANKTNGGITVAEVTGSNVVSVAEHVVMTILLLVRNFVPAHDQIRNG---D 145 Query: 626 WLPHLFVGNL--LKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAY 799 W N L+ + VG +G GRIG R + L+Y+D YQ R E Sbjct: 146 WNVAAVAKNEFDLENKVVGTVGVGRIGERVLRRLKPFDCKELLYYD-YQPLRPEV----- 199 Query: 800 GQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMK------- 958 E+ + +R S+EE++ + DV++++ L + T L N E ++ MK Sbjct: 200 --------EKEIGARRVDSLEEMVSQCDVVTINCPLHEKTRGLFNKELISKMKPGKSALL 251 Query: 959 ----------KEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEPYMK 1087 K + LVN +RG ++ + + E LK+ + G DV+ +P K Sbjct: 252 YLIIPMLMYHKGSWLVNTARGAIVVKEDVAEALKSGHLRGYGGDVWFPQPAPK 304
>Q9S7E4:FDH_ARATH Formate dehydrogenase, mitochondrial precursor - Arabidopsis thaliana| (Mouse-ear cress) Length = 384 Score = 64.3 bits (155), Expect = 1e-09 Identities = 46/165 (27%), Positives = 82/165 (49%), Gaps = 2/165 (1%) Frame = +2 Query: 656 LKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFD-LYQSTRLEKFVTAYGQFLKANGEQP 832 L+G+T+G +GAGRIG + + + F NL+Y D L + LEK A Sbjct: 195 LEGKTIGTVGAGRIGKLLLQRL-KPFGCNLLYHDRLQMAPELEKETGA------------ 241 Query: 833 VTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVA 1012 K + E+L + DVI ++ L + T + N E + +KK ++VN +RG +++ A Sbjct: 242 ---KFVEDLNEMLPKCDVIVINMPLTEKTRGMFNKELIGKLKKGVLIVNNARGAIMERQA 298 Query: 1013 LVEHLKANPMFRVGLDVFEDEPYMKP-GLAEMKNAVVVPHIASAS 1144 +V+ +++ + DV++ +P K M N + PH + + Sbjct: 299 VVDAVESGHIGGYSGDVWDPQPAPKDHPWRYMPNQAMTPHTSGTT 343
>Q6LNU2:PDXB_PHOPR Erythronate-4-phosphate dehydrogenase - Photobacterium profundum| (Photobacterium sp. (strain SS9)) Length = 391 Score = 63.2 bits (152), Expect = 3e-09 Identities = 49/166 (29%), Positives = 80/166 (48%), Gaps = 9/166 (5%) Frame = +2 Query: 665 QTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWK 844 +T+G+IGAG +GS Y ++ + + D + EQ + Sbjct: 118 KTIGIIGAGNVGS-YLAQCLDALGIPYLLNDPIK-------------------EQEGDTR 157 Query: 845 RASSMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVA 1012 + S+E + + DVI++H + K T+HLIN + ++ +A+L+NA+RGPV D A Sbjct: 158 QFHSLEAIKAQCDVITVHTPITKDGEYPTHHLINEAFIDALQPDAILINAARGPVTDNQA 217 Query: 1013 LVEHLKAN-----PMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIA 1135 L + L+ + LDVFE EP++ L + A PHIA Sbjct: 218 LKKALQLSQSGLGKKLTAVLDVFEFEPHVDLELLPLL-AFATPHIA 262
>Q8FFH2:PDXB_ECOL6 Erythronate-4-phosphate dehydrogenase - Escherichia coli O6| Length = 378 Score = 63.2 bits (152), Expect = 3e-09 Identities = 52/178 (29%), Positives = 85/178 (47%), Gaps = 4/178 (2%) Frame = +2 Query: 647 GNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGE 826 G L +TVG++G G +G + +E + + D ++ R ++ G F Sbjct: 111 GFSLHERTVGIVGVGNVGRRL-QARLEALGIKTLLCDPPRADRGDE-----GDF------ 158 Query: 827 QPVTWKRASSMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGP 994 S++E+++ AD+++ H L K T HL + + + +K A+L+NA RG Sbjct: 159 --------RSLDELVQHADILTFHTPLFKDGPYKTLHLADEKLIRSLKPGAILINACRGA 210 Query: 995 VIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA 1168 V+D AL+ L V LDV+E EP + L + K + PHIA +T EG A Sbjct: 211 VVDNTALLTCLNEGQKLSVVLDVWEGEPELNVELLK-KVDIGTPHIAG---YTLEGKA 264
>Q83QR1:PDXB_SHIFL Erythronate-4-phosphate dehydrogenase - Shigella flexneri| Length = 378 Score = 62.8 bits (151), Expect = 4e-09 Identities = 52/178 (29%), Positives = 84/178 (47%), Gaps = 4/178 (2%) Frame = +2 Query: 647 GNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGE 826 G L +TVG++G G +G + +E + + D ++ R ++ G F Sbjct: 111 GFSLHDRTVGIVGVGNVGRRL-QARLEALGIKTLLCDPPRADRGDE-----GDF------ 158 Query: 827 QPVTWKRASSMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGP 994 S++E+++ AD+++ H L K T HL + + + +K A+L+NA RG Sbjct: 159 --------RSLDELVQRADILTFHTPLFKDGPYKTLHLADEKLIRSLKPGAILINACRGA 210 Query: 995 VIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA 1168 V+D AL+ L V LDV+E EP + L K + PHIA +T EG A Sbjct: 211 VVDNTALLTCLNEGQKLSVVLDVWEGEPELNVELL-TKVDIGTPHIAG---YTLEGKA 264
>Q7VRU9:PDXB_BLOFL Erythronate-4-phosphate dehydrogenase - Blochmannia floridanus| Length = 372 Score = 62.0 bits (149), Expect = 7e-09 Identities = 49/168 (29%), Positives = 88/168 (52%), Gaps = 5/168 (2%) Frame = +2 Query: 656 LKGQTVGVIGAGRIGSA-YARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQP 832 L+ +TVG+IG G IG+ Y R+ G ++ + +D Y+S K + ++ Sbjct: 114 LRDKTVGIIGVGNIGNLLYQRLNSLG--VHTLLYDPYKS--------------KCDTDR- 156 Query: 833 VTWKRASSMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVI 1000 ++WK S++ ++ ++D+++LH L T T+H+IN + L + ++L+N SRG V+ Sbjct: 157 MSWK---SLDILVSKSDILTLHVPLTYTGAYPTWHMINKDILDALPSNSILINTSRGAVV 213 Query: 1001 DEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASAS 1144 + L+ L+ V LDV+E EP + L + + HIA S Sbjct: 214 NNDDLLAILRCGKKINVILDVWESEPKLSLPLLSYVD-IGTAHIAGYS 260
>P33677:FDH_PICAN Formate dehydrogenase - Pichia angusta (Yeast) (Hansenula polymorpha)| Length = 362 Score = 60.8 bits (146), Expect = 2e-08 Identities = 54/216 (25%), Positives = 97/216 (44%), Gaps = 4/216 (1%) Frame = +2 Query: 452 VGYNNVDVDAANKNG--IAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDG 625 VG +++D+D N++G I++ G + R V A + + +G G Sbjct: 93 VGSDHIDLDYINQSGRDISVLEVTGSNVVSVAEHVVMTMLVLVRNFVPAHEQIISG---G 149 Query: 626 WLPHLFVGNL--LKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAY 799 W + ++G+ + IGAGRIG ++ L+Y+D YQS Sbjct: 150 WNVAEIAKDSFDIEGKVIATIGAGRIGYRVLERLVAFNPKELLYYD-YQS---------- 198 Query: 800 GQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVN 979 L E+ V +R ++E++ +AD+++++ L + L+N E L KK A LVN Sbjct: 199 ---LSKEAEEKVGARRVHDIKELVAQADIVTINCPLHAGSKGLVNAELLKHFKKGAWLVN 255 Query: 980 ASRGPVIDEVALVEHLKANPMFRVGLDVFEDEPYMK 1087 +RG + + +K+ + G DV+ +P K Sbjct: 256 TARGAICVAEDVAAAVKSGQLRGYGGDVWFPQPAPK 291
>P05459:PDXB_ECOLI Erythronate-4-phosphate dehydrogenase - Escherichia coli| Length = 378 Score = 60.1 bits (144), Expect = 3e-08 Identities = 51/178 (28%), Positives = 84/178 (47%), Gaps = 4/178 (2%) Frame = +2 Query: 647 GNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGE 826 G L +TVG++G G +G + +E + + D ++ R ++ G F Sbjct: 111 GFSLYDRTVGIVGVGNVGRRL-QARLEALGIKTLLCDPPRADRGDE-----GDF------ 158 Query: 827 QPVTWKRASSMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGP 994 S++E+++ AD+++ H L K T HL + + + +K A+L+NA RG Sbjct: 159 --------RSLDELVQRADILTFHTPLFKDGPYKTLHLADEKLIRSLKPGAILINACRGA 210 Query: 995 VIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA 1168 V+D AL+ L V LDV+E EP + L + K + HIA +T EG A Sbjct: 211 VVDNTALLTCLNEGQKLSVVLDVWEGEPELNVELLK-KVDIGTSHIAG---YTLEGKA 264
>Q08987:FDH2_YEAST Formate dehydrogenase 2 - Saccharomyces cerevisiae (Baker's yeast)| Length = 376 Score = 60.1 bits (144), Expect = 3e-08 Identities = 52/214 (24%), Positives = 95/214 (44%), Gaps = 2/214 (0%) Frame = +2 Query: 452 VGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYD--G 625 VG ++VD++AAN+ I + G + R Q G +D G Sbjct: 97 VGSDHVDLEAANERKITVTEVTGSNVVSVAEHVMATILVLIRNYNGGHQQAINGEWDIAG 156 Query: 626 WLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQ 805 + + L+ + + +GAGRIG ++ L+Y+D YQ E Sbjct: 157 VAKNEYD---LEDKIISTVGAGRIGYRVLERLVAFNPKKLLYYD-YQELPAEAINRLNEA 212 Query: 806 FLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNAS 985 NG + +R +E+++ ++DV++++ L K + L N + ++ MK A LVN + Sbjct: 213 SKLFNGRGDIV-QRVEKLEDMVAQSDVVTINCPLHKDSRGLFNKKLISHMKDGAYLVNTA 271 Query: 986 RGPVIDEVALVEHLKANPMFRVGLDVFEDEPYMK 1087 RG + + E +K+ + G DV++ +P K Sbjct: 272 RGAICVAEDVAEAVKSGKLAGYGGDVWDKQPAPK 305
>Q08911:FDH1_YEAST Formate dehydrogenase 1 - Saccharomyces cerevisiae (Baker's yeast)| Length = 376 Score = 60.1 bits (144), Expect = 3e-08 Identities = 52/214 (24%), Positives = 95/214 (44%), Gaps = 2/214 (0%) Frame = +2 Query: 452 VGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYD--G 625 VG ++VD++AAN+ I + G + R Q G +D G Sbjct: 97 VGSDHVDLEAANERKITVTEVTGSNVVSVAEHVMATILVLIRNYNGGHQQAINGEWDIAG 156 Query: 626 WLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQ 805 + + L+ + + +GAGRIG ++ L+Y+D YQ E Sbjct: 157 VAKNEYD---LEDKIISTVGAGRIGYRVLERLVAFNPKKLLYYD-YQELPAEAINRLNEA 212 Query: 806 FLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNAS 985 NG + +R +E+++ ++DV++++ L K + L N + ++ MK A LVN + Sbjct: 213 SKLFNGRGDIV-QRVEKLEDMVAQSDVVTINCPLHKDSRGLFNKKLISHMKDGAYLVNTA 271 Query: 986 RGPVIDEVALVEHLKANPMFRVGLDVFEDEPYMK 1087 RG + + E +K+ + G DV++ +P K Sbjct: 272 RGAICVAEDVAEAVKSGKLAGYGGDVWDKQPAPK 305
>Q8XCR0:PDXB_ECO57 Erythronate-4-phosphate dehydrogenase - Escherichia coli O157:H7| Length = 378 Score = 59.3 bits (142), Expect = 4e-08 Identities = 39/109 (35%), Positives = 59/109 (54%), Gaps = 4/109 (3%) Frame = +2 Query: 854 SMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVE 1021 S++E+++ AD+++ H L K T HL + + + +K A+L+NA RG V+D AL+ Sbjct: 160 SLDELVQRADILTFHTPLFKDGPYKTLHLADEKLIRSLKPGAILINACRGAVVDNTALLT 219 Query: 1022 HLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA 1168 L V LDV+E EP + L K + PHIA +T EG A Sbjct: 220 CLNEGQKLSVVLDVWEGEPELNVELL-TKVDIGTPHIAG---YTLEGKA 264
>Q02961:YP113_YEAST Putative 2-hydroxyacid dehydrogenase YPL113C - Saccharomyces| cerevisiae (Baker's yeast) Length = 396 Score = 58.9 bits (141), Expect = 6e-08 Identities = 44/155 (28%), Positives = 75/155 (48%), Gaps = 1/155 (0%) Frame = +2 Query: 677 VIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASS 856 ++G G IG + + F M++ Y+ ++ ++K + Y ++ + P TWK A Sbjct: 222 ILGFGSIGQNIGSNLHKVFNMSIEYYK--RTGPVQKSLLDYNAKYHSDLDDPNTWKNA-- 277 Query: 857 MEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKAN 1036 D+I L +T ++IN + LA K +VN RG IDE L++ L++ Sbjct: 278 --------DLIILALPSTASTNNIINRKSLAWCKDGVRIVNVGRGTCIDEDVLLDALESG 329 Query: 1037 PMFRVGLDVFE-DEPYMKPGLAEMKNAVVVPHIAS 1138 + GLDVF+ +E +K L + +PHI S Sbjct: 330 KVASCGLDVFKNEETRVKQELLRRWDVTALPHIGS 364
>Q83AR8:PDXB_COXBU Erythronate-4-phosphate dehydrogenase - Coxiella burnetii| Length = 366 Score = 58.5 bits (140), Expect = 8e-08 Identities = 42/97 (43%), Positives = 55/97 (56%), Gaps = 4/97 (4%) Frame = +2 Query: 869 LREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKAN 1036 L D++ LH L KT TYHLI+ L M+K +VL+NA RG VID AL L+ + Sbjct: 165 LANVDLVCLHTPLVKTGNFPTYHLIDNRFLKMLKPGSVLLNAGRGAVIDNNAL---LQCD 221 Query: 1037 PMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASK 1147 + LDV+E+EP + L E K + PHIA SK Sbjct: 222 HVITC-LDVWENEPTVNLQLLE-KTTIATPHIAGYSK 256
>Q7MV70:PDXB_PORGI Erythronate-4-phosphate dehydrogenase - Porphyromonas gingivalis| (Bacteroides gingivalis) Length = 377 Score = 57.8 bits (138), Expect = 1e-07 Identities = 60/225 (26%), Positives = 96/225 (42%), Gaps = 11/225 (4%) Frame = +2 Query: 647 GNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYG-QFL---- 811 G LK + +G++G G +G L++ +AYG +FL Sbjct: 119 GFSLKEKVMGIVGVGHVGG-----------------------ELKRLASAYGMEFLLCDP 155 Query: 812 -KANGEQPVTWKRASSMEEVLREADVISLHPVL----DKTTYHLINPERL-AMMKKEAVL 973 ++ EQ ++ S + E + D+IS H L TYHLI L + K +L Sbjct: 156 PRSEAEQDNSFLPLSRLVE---QCDIISFHVPLTHEDPHATYHLIGEAFLRSCADKRPIL 212 Query: 974 VNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWT 1153 +NA RG V D AL+ +K+ + + +D +E EP + L ++ + + PHIA S Sbjct: 213 INACRGAVADTQALIRAVKSGWLQALVIDCWEGEPDIDLSLLDLAD-IATPHIAGFSADG 271 Query: 1154 REGMATLAALNVLGKIKGYPVWGNPNAVEPFLDEEATPPPACPSI 1288 + A + L + ++ G P L A PPP P I Sbjct: 272 KANGARM-CLEAITEVFGLEF--------PLLHTLAPPPPTHPII 307
>P33160:FDH_PSESR Formate dehydrogenase - Pseudomonas sp. (strain 101) (Achromobacter| parvulus T1) Length = 401 Score = 56.2 bits (134), Expect = 4e-07 Identities = 54/214 (25%), Positives = 95/214 (44%), Gaps = 2/214 (0%) Frame = +2 Query: 452 VGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWL 631 +G ++VD+ +A + + + + R + + ++ R G GW Sbjct: 123 IGSDHVDLQSAIDRNVTVAEVTYCNSISVAEHVVMMILSLVRNYLPSHEWARKG---GWN 179 Query: 632 PHLFVGNL--LKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQ 805 V + L+ VG + AGRIG A R + F ++L Y D + RL + V Sbjct: 180 IADCVSHAYDLEAMHVGTVAAGRIGLAVLRRLAP-FDVHLHYTDRH---RLPESVEK--- 232 Query: 806 FLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNAS 985 E +TW ++ E++ DV++L+ L T H+IN E L + K+ A +VN + Sbjct: 233 ------ELNLTWH--ATREDMYPVCDVVTLNCPLHPETEHMINDETLKLFKRGAYIVNTA 284 Query: 986 RGPVIDEVALVEHLKANPMFRVGLDVFEDEPYMK 1087 RG + D A+ L++ + DV+ +P K Sbjct: 285 RGKLCDRDAVARALESGRLAGYAGDVWFPQPAPK 318
>P53100:YGT5_YEAST Putative 2-hydroxyacid dehydrogenase YGL185C - Saccharomyces| cerevisiae (Baker's yeast) Length = 379 Score = 49.3 bits (116), Expect = 5e-05 Identities = 46/189 (24%), Positives = 74/189 (39%), Gaps = 6/189 (3%) Frame = +2 Query: 659 KGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVT 838 +G+ ++G G IG A + G M + Y + + Q + Sbjct: 196 RGKKCLILGLGSIGKQVAYKLQYGLGMEIHYCKRSEDCTMS---------------QNES 240 Query: 839 WKRASSMEEVLREADVISLHPVL-----DKTTYHLINPERLAMMKKEAVLVNASRGPVID 1003 WK E + A + H ++ T HLIN + L +LVN RG ++D Sbjct: 241 WKFHLLDETIY--AKLYQFHAIVVTLPGTPQTEHLINRKFLEHCNPGLILVNLGRGKILD 298 Query: 1004 EVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAV-VVPHIASASKWTREGMATLAA 1180 A+ + L + +GLDVF EP + + + PH+ SA+K E LA Sbjct: 299 LRAVSDALVTGRINHLGLDVFNKEPEIDEKIRSSDRLTSITPHLGSATKDVFEQSCELAL 358 Query: 1181 LNVLGKIKG 1207 +L + G Sbjct: 359 TRILRVVSG 367
>Q09054:G3PD_MAIZE Glyceraldehyde-3-phosphate dehydrogenase, cytosolic 2 - Zea mays| (Maize) Length = 337 Score = 33.9 bits (76), Expect = 2.0 Identities = 39/163 (23%), Positives = 66/163 (40%), Gaps = 5/163 (3%) Frame = +2 Query: 671 VGVIGAGRIGSAYARMMIEGFKMNLI-----YFDLYQSTRLEKFVTAYGQFLKANGEQPV 835 +G+ G GRIG AR+ ++ + L+ + T + K+ T +GQ Sbjct: 6 IGINGFGRIGRLVARVALQSEDVELVAVNDPFITTDYMTYMFKYDTVHGQ---------- 55 Query: 836 TWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVAL 1015 WK + + L+++ + L T + + NPE + + A V S G D+ Sbjct: 56 -WKHS---DIALKDSKTL-LFGEKPVTVFGIRNPEEIPWGEAGAEYVVESTGVFTDKDKA 110 Query: 1016 VEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASAS 1144 HLK V +D P G+ E K V +++AS Sbjct: 111 AAHLKGGAKKVVISAPSKDAPMFVVGVNEDKYTSDVNIVSNAS 153
>P75913:YCDW_ECOLI Putative 2-hydroxyacid dehydrogenase ycdW - Escherichia coli| Length = 325 Score = 33.5 bits (75), Expect = 2.6 Identities = 42/162 (25%), Positives = 70/162 (43%), Gaps = 2/162 (1%) Frame = +2 Query: 668 TVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKR 847 T+G++GAG +GS A+ + F L +R K F A E+ Sbjct: 151 TIGILGAGVLGSKVAQ------SLQTWRFPLRCWSRTRKSWPGVQSF--AGREE------ 196 Query: 848 ASSMEEVLREADV-ISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEH 1024 + L + V I+L P +T +IN + L + A L+N +RG + E L+ Sbjct: 197 ---LSAFLSQCRVLINLLPNTPETV-GIINQQLLEKLPDGAYLLNLARGVHVVEDDLLAA 252 Query: 1025 LKANPMFRVGLDVFEDEPY-MKPGLAEMKNAVVVPHIASASK 1147 L + + LDVF EP + L + + PH+A+ ++ Sbjct: 253 LDSGKVKGAMLDVFNREPLPPESPLWQHPRVTITPHVAAITR 294
>Q0J8A4:G3PC_ORYSJ Glyceraldehyde-3-phosphate dehydrogenase, cytosolic - Oryza sativa| subsp. japonica (Rice) Length = 337 Score = 33.1 bits (74), Expect = 3.4 Identities = 38/163 (23%), Positives = 66/163 (40%), Gaps = 5/163 (3%) Frame = +2 Query: 671 VGVIGAGRIGSAYARMMIEGFKMNLI-----YFDLYQSTRLEKFVTAYGQFLKANGEQPV 835 +G+ G GRIG AR+ ++ + L+ + T + K+ T +GQ Sbjct: 6 IGINGFGRIGRLVARVALQSEDVELVAVNDPFITTDYMTYMFKYDTVHGQ---------- 55 Query: 836 TWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVAL 1015 WK S ++ + ++ PV T + + NP+ + + A V S G D+ Sbjct: 56 -WKH-SDIKIKDSKTLLLGEKPV---TVFGIRNPDEIPWAEAGAEYVVESTGVFTDKEKA 110 Query: 1016 VEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASAS 1144 HLK V +D P G+ E K + +++AS Sbjct: 111 AAHLKGGAKKVVISAPSKDAPMFVCGVNEDKYTSDIDIVSNAS 153
>A2YQT7:G3PC_ORYSI Glyceraldehyde-3-phosphate dehydrogenase, cytosolic - Oryza sativa| subsp. indica (Rice) Length = 337 Score = 33.1 bits (74), Expect = 3.4 Identities = 38/163 (23%), Positives = 66/163 (40%), Gaps = 5/163 (3%) Frame = +2 Query: 671 VGVIGAGRIGSAYARMMIEGFKMNLI-----YFDLYQSTRLEKFVTAYGQFLKANGEQPV 835 +G+ G GRIG AR+ ++ + L+ + T + K+ T +GQ Sbjct: 6 IGINGFGRIGRLVARVALQSEDVELVAVNDPFITTDYMTYMFKYDTVHGQ---------- 55 Query: 836 TWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVAL 1015 WK S ++ + ++ PV T + + NP+ + + A V S G D+ Sbjct: 56 -WKH-SDIKIKDSKTLLLGEKPV---TVFGIRNPDEIPWAEAGAEYVVESTGVFTDKEKA 110 Query: 1016 VEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASAS 1144 HLK V +D P G+ E K + +++AS Sbjct: 111 AAHLKGGAKKVVISAPSKDAPMFVCGVNEDKYTSDIDIVSNAS 153
>A2QW93:HSE1_ASPNG Class E vacuolar protein-sorting machinery protein hse1 -| Aspergillus niger Length = 611 Score = 32.7 bits (73), Expect = 4.4 Identities = 17/51 (33%), Positives = 25/51 (49%) Frame = +1 Query: 223 GEHQVHAWHPLDQAPH*QRLPP*DMHGEEDHPLRRRHPGSHRRSLPRCHRP 375 G Q HA+ P Q+P ++ PP ++ P ++R P S P HRP Sbjct: 428 GTEQAHAYPPTSQSPDPRQTPPAGAPYQQPQPQQQRQPSSESYQ-PVYHRP 477
>P26517:G3PX_HORVU Glyceraldehyde-3-phosphate dehydrogenase, cytosolic - Hordeum vulgare| (Barley) Length = 337 Score = 32.7 bits (73), Expect = 4.4 Identities = 38/163 (23%), Positives = 63/163 (38%), Gaps = 5/163 (3%) Frame = +2 Query: 671 VGVIGAGRIGSAYARMMIEGFKMNLI-----YFDLYQSTRLEKFVTAYGQFLKANGEQPV 835 +G+ G GRIG AR+ ++ + L+ + T + K+ T +G Sbjct: 6 IGINGFGRIGRLVARVALQSDDVELVAVNDPFITTEYMTYMFKYDTVHGH---------- 55 Query: 836 TWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVAL 1015 WK + ++ + D L T + + NPE + + A V S G D+ Sbjct: 56 -WKHS----DIKLKDDKTLLFGEKPVTVFGVRNPEEIPWGEAGADYVVESTGVFTDKDKA 110 Query: 1016 VEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASAS 1144 HLK V +D P G+ E K V +++AS Sbjct: 111 AAHLKGGAKKVVISAPSKDAPMFVVGVNEDKYTSDVNIVSNAS 153
>P26520:G3PC_PETHY Glyceraldehyde-3-phosphate dehydrogenase, cytosolic - Petunia hybrida| (Petunia) Length = 337 Score = 32.7 bits (73), Expect = 4.4 Identities = 40/166 (24%), Positives = 63/166 (37%), Gaps = 18/166 (10%) Frame = +2 Query: 671 VGVIGAGRIGSAYARMMIEGFKMNLI-----YFDLYQSTRLEKFVTAYGQFLKANGEQPV 835 +G+ G GRIG AR+ ++ + L+ + + T + K+ + +GQ Sbjct: 6 IGINGFGRIGRLVARVALQRDDVELVAVNDPFISVEYMTYMFKYDSVHGQ---------- 55 Query: 836 TWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVAL 1015 WK E+ + D L T + + NPE + + A V S G D+ Sbjct: 56 -WKH----HELKAKDDKTLLFGEKPVTVFGIRNPEEIPWGEAGADYVVESTGVFTDKDKA 110 Query: 1016 VEHLKAN-------------PMFRVGLDVFEDEPYMKPGLAEMKNA 1114 HLK PMF VG+ +E K L + NA Sbjct: 111 AAHLKGGAKKVIISAPSKDAPMFVVGV----NEKEYKSDLTVVSNA 152
>Q9X2N4:DLTA_STAXY D-alanine--poly(phosphoribitol) ligase subunit 1 - Staphylococcus| xylosus Length = 487 Score = 32.3 bits (72), Expect = 5.8 Identities = 20/50 (40%), Positives = 29/50 (58%), Gaps = 9/50 (18%) Frame = +3 Query: 1458 LPVYMY-ECTHLHGVVVMNEMS--------IYSIKQEIFYQLCIYMFPRK 1580 +PVY + T L GVVV+N+++ I+ IKQE+ + YM PRK Sbjct: 412 VPVYKNNKVTQLQGVVVLNDLNDDKDEQTVIHDIKQELKQAMPEYMIPRK 461
>P08735:G3PC_MAIZE Glyceraldehyde-3-phosphate dehydrogenase, cytosolic 1 - Zea mays| (Maize) Length = 337 Score = 32.0 bits (71), Expect = 7.5 Identities = 38/163 (23%), Positives = 67/163 (41%), Gaps = 5/163 (3%) Frame = +2 Query: 671 VGVIGAGRIGSAYARMMIEGFKMNLI-----YFDLYQSTRLEKFVTAYGQFLKANGEQPV 835 +G+ G GRIG AR+ ++ + L+ + T + K+ T +G + ++ + Sbjct: 6 IGINGFGRIGRLVARVALQSEDVELVAVNDPFITTDYMTYMFKYDTVHGHWKHSD----I 61 Query: 836 TWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVAL 1015 T K + ++ + PV T + + NPE + + A V S G D+ Sbjct: 62 TLKDSKTL--------LFGDKPV---TVFGIRNPEEIPWGEAGAEYVVESTGVFTDKDKA 110 Query: 1016 VEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASAS 1144 HLK V +D P G+ E K V +++AS Sbjct: 111 AAHLKGGAKKVVISAPSKDAPMFVVGVNEDKYTSDVNIVSNAS 153
>O51934:RGYR_THEMA Reverse gyrase [Includes: Helicase - Thermotoga maritima| Length = 1104 Score = 31.6 bits (70), Expect = 9.8 Identities = 19/67 (28%), Positives = 34/67 (50%) Frame = +2 Query: 683 GAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSME 862 G GR S YA+++ F+ +Y D Y+ R +F +LK E+ VT + +E Sbjct: 1015 GIGR-PSTYAKIVEVLFRRGYVYEDKYKRVRPTRFGVMVYSYLKERYEKYVTEETTRRLE 1073 Query: 863 EVLREAD 883 E++ + + Sbjct: 1074 EIMDKVE 1080
>Q9GKQ1:HSP1_SAISC Sperm protamine-P1 - Saimiri sciureus (Common squirrel monkey)| Length = 50 Score = 31.6 bits (70), Expect = 9.8 Identities = 17/37 (45%), Positives = 20/37 (54%) Frame = -1 Query: 512 CCRWRCRSCWQHRRQRCCTRQPYC*RLSHQRA*GQRR 402 CCR R RS RR+RC TR+ C R R +RR Sbjct: 6 CCRSRSRSRCYRRRRRCRTRRRRCCRRRRARRCCRRR 42
>P33450:FAT_DROME Cadherin-related tumor suppressor precursor - Drosophila melanogaster| (Fruit fly) Length = 5147 Score = 31.6 bits (70), Expect = 9.8 Identities = 18/65 (27%), Positives = 33/65 (50%) Frame = +2 Query: 755 DLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLIN 934 ++ +T L++ T+ + +T RASS+ + +DV P D TTY++ Sbjct: 2546 EISTATTLDREETSVYHLTLMAQDSSITEPRASSVNLTISVSDVNDNIPKFDSTTYNVAV 2605 Query: 935 PERLA 949 PER++ Sbjct: 2606 PERIS 2610
>Q8TGE1:AWA1_YEAST Cell wall protein AWA1 precursor - Saccharomyces cerevisiae (Baker's| yeast) Length = 1713 Score = 31.6 bits (70), Expect = 9.8 Identities = 35/120 (29%), Positives = 54/120 (45%), Gaps = 8/120 (6%) Frame = -3 Query: 1296 ALTMLGQAGGGVASSS-----RKGSTAFGFPHTGYPLILPSTFRAASVAIPSRVHLDADA 1132 ++T G A G ASS+ + GS+ G + P I S ++ S A + + + Sbjct: 691 SITQSGTASGSSASSTSGSVTQSGSSVSGSSASSAPGISSSIPQSTSSASTASGSITS-- 748 Query: 1131 M*GTTTAFFISASPGFM*GSSSKTSRPTRNMGLALRCSTSAT---SSITGPRLAFTSTAS 961 GT T+ +S GSS+ S G ++ STSAT SS++G A S +S Sbjct: 749 --GTLTSITSGSSSATESGSSASGSSSATESGSSVSGSTSATESGSSVSGSTSATESGSS 806 Database: uniprot_sprot.fasta.out Posted date: Jul 19, 2007 5:58 PM Number of letters in database: 100,686,439 Number of sequences in database: 274,295 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 274295 Number of Hits to DB: 261,456,309 Number of extensions: 5602805 Number of successful extensions: 18165 Number of sequences better than 10.0: 131 Number of HSP's gapped: 17941 Number of HSP's successfully gapped: 132 Length of query: 531 Length of database: 100,686,439 Length adjustment: 118 Effective length of query: 413 Effective length of database: 68,319,629 Effective search space: 28216006777 Effective search space used: 28216006777 Neighboring words threshold: 12 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)