ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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更新日:2016年5月1日

Clone Information

BLAST Search Result

Clone Name FLbaf95m06
Clone Library Name barley_pub

No. Definition Score
(bits)
E
Value
1P13443:DHGY_CUCSA Glycerate dehydrogenase - Cucumis sativus (Cuc... 650 0.0
2Q9C4M5:GYAR_THELI Glyoxylate reductase - Thermococcus litoralis 192 3e-48
3O58320:GYAR_PYRHO Glyoxylate reductase - Pyrococcus horikoshii 183 2e-45
4Q9UYR1:GYAR_PYRAB Glyoxylate reductase - Pyrococcus abyssi 183 2e-45
5Q5JEZ2:GYAR_PYRKO Glyoxylate reductase - Pyrococcus kodakaraensi... 180 2e-44
6Q8U3Y2:GYAR_PYRFU Glyoxylate reductase - Pyrococcus furiosus 174 1e-42
7Q9YAW4:GYAR_AERPE Glyoxylate reductase - Aeropyrum pernix 170 2e-41
8P37666:TKRA_ECOLI 2-ketogluconate reductase - Escherichia coli 143 2e-33
9P58220:TKRA_ECO57 2-ketogluconate reductase - Escherichia coli O... 143 2e-33
10P58000:TKRA_ENTAG 2-ketogluconate reductase - Enterobacter agglo... 142 3e-33
11O32264:TKRA_BACSU Probable 2-ketogluconate reductase - Bacillus ... 142 5e-33
12O27051:SERA_METTH D-3-phosphoglycerate dehydrogenase - Methanoba... 129 3e-29
13Q9UBQ7:GRHPR_HUMAN Glyoxylate reductase/hydroxypyruvate reductas... 125 7e-28
14O29445:SERA_ARCFU D-3-phosphoglycerate dehydrogenase - Archaeogl... 122 3e-27
15O04130:SERA_ARATH D-3-phosphoglycerate dehydrogenase, chloroplas... 121 7e-27
16Q91Z53:GRHPR_MOUSE Glyoxylate reductase/hydroxypyruvate reductas... 120 1e-26
17P35136:SERA_BACSU D-3-phosphoglycerate dehydrogenase - Bacillus ... 119 3e-26
18Q58424:SERA_METJA D-3-phosphoglycerate dehydrogenase - Methanoco... 118 8e-26
19P36234:DHGY_HYPME Glycerate dehydrogenase - Hyphomicrobium methy... 117 1e-25
20O33116:SERA_MYCLE D-3-phosphoglycerate dehydrogenase - Mycobacte... 112 4e-24
21O69054:PTXD_PSEST Phosphonate dehydrogenase - Pseudomonas stutze... 107 1e-22
22P53839:YN14_YEAST Putative 2-hydroxyacid dehydrogenase YNL274C -... 105 4e-22
23O43175:SERA_HUMAN D-3-phosphoglycerate dehydrogenase - Homo sapi... 105 4e-22
24Q61753:SERA_MOUSE D-3-phosphoglycerate dehydrogenase - Mus muscu... 105 5e-22
25Q9W758:CTBP2_XENLA C-terminal-binding protein 2 - Xenopus laevis... 105 5e-22
26O08651:SERA_RAT D-3-phosphoglycerate dehydrogenase - Rattus norv... 105 7e-22
27Q60HD7:SERA_MACFA D-3-phosphoglycerate dehydrogenase - Macaca fa... 105 7e-22
28P56545:CTBP2_HUMAN C-terminal-binding protein 2 - Homo sapiens (... 105 7e-22
29O94574:YGDH_SCHPO Putative 2-hydroxyacid dehydrogenase C1773.17c... 104 9e-22
30O14075:YEAA_SCHPO Putative 2-hydroxyacid dehydrogenase UNK4.10 -... 104 9e-22
31P0A544:SERA_MYCTU D-3-phosphoglycerate dehydrogenase - Mycobacte... 104 9e-22
32P0A545:SERA_MYCBO D-3-phosphoglycerate dehydrogenase - Mycobacte... 104 9e-22
33P56546:CTBP2_MOUSE C-terminal-binding protein 2 - Mus musculus (... 104 9e-22
34Q0VCQ1:CTBP2_BOVIN C-terminal-binding protein 2 - Bos taurus (Bo... 104 1e-21
35Q9Z2F5:CTBP1_RAT C-terminal-binding protein 1 - Rattus norvegicu... 104 1e-21
36O88712:CTBP1_MOUSE C-terminal-binding protein 1 - Mus musculus (... 104 1e-21
37Q13363:CTBP1_HUMAN C-terminal-binding protein 1 - Homo sapiens (... 103 2e-21
38P52643:LDHD_ECOLI D-lactate dehydrogenase - Escherichia coli 103 2e-21
39Q9YHU0:CTBP1_XENLA C-terminal-binding protein 1 - Xenopus laevis... 103 3e-21
40Q5EAD2:SERA_BOVIN D-3-phosphoglycerate dehydrogenase - Bos tauru... 102 3e-21
41Q5R7M2:SERA_PONPY D-3-phosphoglycerate dehydrogenase - Pongo pyg... 102 5e-21
42P26297:LDHD_LACDA D-lactate dehydrogenase - Lactobacillus delbru... 102 5e-21
43P44501:DDH_HAEIN 2-hydroxyacid dehydrogenase homolog - Haemophil... 102 6e-21
44P30901:LDHD_LACHE D-lactate dehydrogenase - Lactobacillus helvet... 101 8e-21
45P30799:DDH_ZYMMO 2-hydroxyacid dehydrogenase homolog - Zymomonas... 100 2e-20
46O46036:CTBP_DROME C-terminal-binding protein - Drosophila melano... 100 2e-20
47P73821:SERA_SYNY3 D-3-phosphoglycerate dehydrogenase - Synechocy... 99 5e-20
48Q59642:LDHD_PEDAC D-lactate dehydrogenase - Pediococcus acidilac... 97 1e-19
49P43885:SERA_HAEIN D-3-phosphoglycerate dehydrogenase - Haemophil... 97 2e-19
50P45250:Y1556_HAEIN Putative 2-hydroxyacid dehydrogenase HI1556 -... 94 2e-18
51Q6GDS2:LDHD_STAAR D-lactate dehydrogenase - Staphylococcus aureu... 92 8e-18
52Q8NUT2:LDHD_STAAW D-lactate dehydrogenase - Staphylococcus aureu... 91 1e-17
53Q6G6F1:LDHD_STAAS D-lactate dehydrogenase - Staphylococcus aureu... 91 1e-17
54P72357:LDHD_STAAU D-lactate dehydrogenase - Staphylococcus aureus 91 2e-17
55Q5HD29:LDHD_STAAC D-lactate dehydrogenase - Staphylococcus aureu... 91 2e-17
56P0A9T3:SERA_SHIFL D-3-phosphoglycerate dehydrogenase - Shigella ... 90 2e-17
57P0A9T0:SERA_ECOLI D-3-phosphoglycerate dehydrogenase - Escherich... 90 2e-17
58P0A9T1:SERA_ECOL6 D-3-phosphoglycerate dehydrogenase - Escherich... 90 2e-17
59P0A9T2:SERA_ECO57 D-3-phosphoglycerate dehydrogenase - Escherich... 90 2e-17
60P99116:LDHD_STAAN D-lactate dehydrogenase - Staphylococcus aureu... 90 2e-17
61P63940:LDHD_STAAM D-lactate dehydrogenase - Staphylococcus aureu... 90 2e-17
62Q59516:DHGY_METEX Glycerate dehydrogenase - Methylobacterium ext... 90 2e-17
63P87228:SERA_SCHPO Putative D-3-phosphoglycerate dehydrogenase - ... 89 7e-17
64P51011:LDHD_LEUMC D-lactate dehydrogenase - Leuconostoc mesenter... 88 1e-16
65P40054:SERA_YEAST D-3-phosphoglycerate dehydrogenase 1 - Sacchar... 87 2e-16
66Q8CN22:LDHD_STAES D-lactate dehydrogenase - Staphylococcus epide... 87 2e-16
67Q5HLA0:LDHD_STAEQ D-lactate dehydrogenase - Staphylococcus epide... 87 2e-16
68O83080:LDHD_TREPA D-lactate dehydrogenase - Treponema pallidum 86 6e-16
69Q8DB36:PDXB_VIBVU Erythronate-4-phosphate dehydrogenase - Vibrio... 85 7e-16
70Q47748:VANH_ENTFA D-specific alpha-keto acid dehydrogenase - Ent... 85 1e-15
71Q7MIT6:PDXB_VIBVY Erythronate-4-phosphate dehydrogenase - Vibrio... 85 1e-15
72Q8E0N5:LDHD_STRA5 D-lactate dehydrogenase - Streptococcus agalac... 85 1e-15
73P40510:SER33_YEAST D-3-phosphoglycerate dehydrogenase 2 - Saccha... 84 1e-15
74P17584:DHD2_LACPA D-2-hydroxyisocaproate dehydrogenase - Lactoba... 84 1e-15
75Q99ZM2:LDHD_STRP1 D-lactate dehydrogenase - Streptococcus pyogen... 84 2e-15
76Q05709:VANH_ENTFC D-specific alpha-keto acid dehydrogenase - Ent... 82 5e-15
77Q7N2B2:PDXB_PHOLL Erythronate-4-phosphate dehydrogenase - Photor... 81 1e-14
78Q8E6A9:LDHD_STRA3 D-lactate dehydrogenase - Streptococcus agalac... 81 1e-14
79Q88VJ2:LDHD_LACPL D-lactate dehydrogenase - Lactobacillus plantarum 80 2e-14
80Q9KQ92:PDXB_VIBCH Erythronate-4-phosphate dehydrogenase - Vibrio... 79 7e-14
81P26298:LDHD_LACPE D-lactate dehydrogenase - Lactobacillus pentosus 77 2e-13
82Q07103:FDH_NEUCR Formate dehydrogenase - Neurospora crassa 77 2e-13
83Q9I3W9:PDXB_PSEAE Erythronate-4-phosphate dehydrogenase - Pseudo... 75 6e-13
84Q87MN8:PDXB_VIBPA Erythronate-4-phosphate dehydrogenase - Vibrio... 75 8e-13
85Q8ECR2:PDXB_SHEON Erythronate-4-phosphate dehydrogenase - Shewan... 74 2e-12
86Q884R9:PDXB_PSESM Erythronate-4-phosphate dehydrogenase - Pseudo... 74 2e-12
87Q88L20:PDXB_PSEPK Erythronate-4-phosphate dehydrogenase - Pseudo... 74 2e-12
88Q668W7:PDXB_YERPS Erythronate-4-phosphate dehydrogenase - Yersin... 71 1e-11
89Q8D0U3:PDXB_YERPE Erythronate-4-phosphate dehydrogenase - Yersin... 71 1e-11
90Q9SXP2:FDH1_ORYSJ Formate dehydrogenase 1, mitochondrial precurs... 71 1e-11
91P60802:PDXB_SALTY Erythronate-4-phosphate dehydrogenase - Salmon... 71 1e-11
92P60801:PDXB_SALTI Erythronate-4-phosphate dehydrogenase - Salmon... 71 1e-11
93Q9ZRI8:FDH_HORVU Formate dehydrogenase, mitochondrial precursor ... 70 2e-11
94Q8D2P6:PDXB_WIGBR Erythronate-4-phosphate dehydrogenase - Wiggle... 68 9e-11
95Q56733:PDXB_SHEVI Erythronate-4-phosphate dehydrogenase - Shewan... 68 1e-10
96Q07511:FDH_SOLTU Formate dehydrogenase, mitochondrial precursor ... 67 2e-10
97Q56731:PDXB_SHESP Erythronate-4-phosphate dehydrogenase - Shewan... 67 2e-10
98Q8A2E4:PDXB_BACTN Erythronate-4-phosphate dehydrogenase - Bacter... 67 2e-10
99Q67U69:FDH2_ORYSJ Formate dehydrogenase 2, mitochondrial precurs... 66 4e-10
100P0C1E9:YPRB2_CORML Uncharacterized protein in proB 3'region - Co... 66 5e-10
101P0C1E8:Y2355_CORGL Uncharacterized protein Cgl2355/cg2587 - Cory... 65 1e-09
102Q6D2N5:PDXB_ERWCT Erythronate-4-phosphate dehydrogenase - Erwini... 64 1e-09
103Q03134:FDH_EMENI Probable formate dehydrogenase - Emericella nid... 64 1e-09
104Q9S7E4:FDH_ARATH Formate dehydrogenase, mitochondrial precursor ... 64 1e-09
105Q6LNU2:PDXB_PHOPR Erythronate-4-phosphate dehydrogenase - Photob... 63 3e-09
106Q8FFH2:PDXB_ECOL6 Erythronate-4-phosphate dehydrogenase - Escher... 63 3e-09
107Q83QR1:PDXB_SHIFL Erythronate-4-phosphate dehydrogenase - Shigel... 63 4e-09
108Q7VRU9:PDXB_BLOFL Erythronate-4-phosphate dehydrogenase - Blochm... 62 7e-09
109P33677:FDH_PICAN Formate dehydrogenase - Pichia angusta (Yeast) ... 61 2e-08
110P05459:PDXB_ECOLI Erythronate-4-phosphate dehydrogenase - Escher... 60 3e-08
111Q08987:FDH2_YEAST Formate dehydrogenase 2 - Saccharomyces cerevi... 60 3e-08
112Q08911:FDH1_YEAST Formate dehydrogenase 1 - Saccharomyces cerevi... 60 3e-08
113Q8XCR0:PDXB_ECO57 Erythronate-4-phosphate dehydrogenase - Escher... 59 4e-08
114Q02961:YP113_YEAST Putative 2-hydroxyacid dehydrogenase YPL113C ... 59 6e-08
115Q83AR8:PDXB_COXBU Erythronate-4-phosphate dehydrogenase - Coxiel... 59 8e-08
116Q7MV70:PDXB_PORGI Erythronate-4-phosphate dehydrogenase - Porphy... 58 1e-07
117P33160:FDH_PSESR Formate dehydrogenase - Pseudomonas sp. (strain... 56 4e-07
118P53100:YGT5_YEAST Putative 2-hydroxyacid dehydrogenase YGL185C -... 49 5e-05
119Q09054:G3PD_MAIZE Glyceraldehyde-3-phosphate dehydrogenase, cyto... 34 2.0
120P75913:YCDW_ECOLI Putative 2-hydroxyacid dehydrogenase ycdW - Es... 33 2.6
121Q0J8A4:G3PC_ORYSJ Glyceraldehyde-3-phosphate dehydrogenase, cyto... 33 3.4
122A2YQT7:G3PC_ORYSI Glyceraldehyde-3-phosphate dehydrogenase, cyto... 33 3.4
123A2QW93:HSE1_ASPNG Class E vacuolar protein-sorting machinery pro... 33 4.4
124P26517:G3PX_HORVU Glyceraldehyde-3-phosphate dehydrogenase, cyto... 33 4.4
125P26520:G3PC_PETHY Glyceraldehyde-3-phosphate dehydrogenase, cyto... 33 4.4
126Q9X2N4:DLTA_STAXY D-alanine--poly(phosphoribitol) ligase subunit... 32 5.8
127P08735:G3PC_MAIZE Glyceraldehyde-3-phosphate dehydrogenase, cyto... 32 7.5
128O51934:RGYR_THEMA Reverse gyrase [Includes: Helicase - Thermotog... 32 9.8
129Q9GKQ1:HSP1_SAISC Sperm protamine-P1 - Saimiri sciureus (Common ... 32 9.8
130P33450:FAT_DROME Cadherin-related tumor suppressor precursor - D... 32 9.8
131Q8TGE1:AWA1_YEAST Cell wall protein AWA1 precursor - Saccharomyc... 32 9.8

>P13443:DHGY_CUCSA Glycerate dehydrogenase - Cucumis sativus (Cucumber)|
          Length = 382
 Score =  650 bits (1677), Expect = 0.0
 Identities = 316/380 (83%), Positives = 342/380 (90%)
 Frame = +2

Query: 170  MAKPISIEVWNPSGKYRVVSTKSMPGTRWIKLLTDNDCRLEICTEKKTILSVDDILALIG 349
            MAKP+ IEVWNP+GKYRVVSTK MPGTRWI LL + DCR+EICTEKKTILSV+DILALIG
Sbjct: 1    MAKPVQIEVWNPNGKYRVVSTKPMPGTRWINLLIEQDCRVEICTEKKTILSVEDILALIG 60

Query: 350  DHCHGVIGQLTEDWGEVLFSALKRAGGTAFSNMAVGYNNVDVDAANKNGIAIGNTPGVLT 529
            D C GVIGQLTEDWGEVLFSAL RAGG AFSNMAVGYNNVDV+AANK G+A+GNTPGVLT
Sbjct: 61   DKCDGVIGQLTEDWGEVLFSALSRAGGKAFSNMAVGYNNVDVNAANKYGVAVGNTPGVLT 120

Query: 530  ETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAY 709
            ETT            RRIVEAD+FMRAG YDGWLP+LFVGNLLKGQTVGVIGAGRIGSAY
Sbjct: 121  ETTAELAASLSLAAARRIVEADEFMRAGRYDGWLPNLFVGNLLKGQTVGVIGAGRIGSAY 180

Query: 710  ARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADVI 889
            ARMM+EGFKMNLIYFDLYQSTRLEKFVTAYG+FLKANGE PVTW+RASSM+EVLREADVI
Sbjct: 181  ARMMVEGFKMNLIYFDLYQSTRLEKFVTAYGEFLKANGEAPVTWRRASSMDEVLREADVI 240

Query: 890  SLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFE 1069
            SLHPVLDKTT+HL+N E L  MKK+A+L+N SRGPVIDE ALV+HL+ NPMFRVGLDVFE
Sbjct: 241  SLHPVLDKTTFHLVNKESLKAMKKDAILINCSRGPVIDEAALVDHLRDNPMFRVGLDVFE 300

Query: 1070 DEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKGYPVWGNPNAVEPFL 1249
            DEPYMKPGLA+MKNA++VPHIASASKWTREGMATLAALNVLGKIKGYPVW +PN VEPFL
Sbjct: 301  DEPYMKPGLADMKNAIIVPHIASASKWTREGMATLAALNVLGKIKGYPVWSDPNRVEPFL 360

Query: 1250 DEEATPPPACPSIVNAKQLG 1309
            DE  +PP A PSIVNAK LG
Sbjct: 361  DENVSPPAASPSIVNAKALG 380



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>Q9C4M5:GYAR_THELI Glyoxylate reductase - Thermococcus litoralis|
          Length = 331

 Score =  192 bits (489), Expect = 3e-48
 Identities = 111/258 (43%), Positives = 152/258 (58%), Gaps = 5/258 (1%)
 Frame = +2

Query: 449  AVGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYD-- 622
            AVGY+N+D++ A K GI + NTPGVLT+ T            RRIVEAD F+R+G +   
Sbjct: 75   AVGYDNIDIEEATKRGIYVTNTPGVLTDATADLAFALLLAVARRIVEADAFVRSGEWKKS 134

Query: 623  --GWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTA 796
              GW P +F+G  LKG+T+G++G GRIG A A+   +GF M +IY+   +    E+ + A
Sbjct: 135  EVGWHPLMFLGYGLKGKTLGIVGFGRIGQALAKRA-KGFGMKIIYYSRTRKPEAEEEIGA 193

Query: 797  -YGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVL 973
             Y  F                 E +L+E+D ISLH  L K TYH+I  + L +MK  A+L
Sbjct: 194  EYVDF-----------------ETLLKESDFISLHVPLTKETYHMIGEKELKLMKPNAIL 236

Query: 974  VNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWT 1153
            +N SRG V+D  AL++ LK   +   GLDVFE+EPY    L ++KN V+ PHI SA+   
Sbjct: 237  INTSRGAVVDTNALIKALKEGWIAGAGLDVFEEEPYYNEELFKLKNVVLAPHIGSATHEA 296

Query: 1154 REGMATLAALNVLGKIKG 1207
            REGMA L A N++   KG
Sbjct: 297  REGMAELVAKNLIAFAKG 314



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>O58320:GYAR_PYRHO Glyoxylate reductase - Pyrococcus horikoshii|
          Length = 334

 Score =  183 bits (465), Expect = 2e-45
 Identities = 120/336 (35%), Positives = 182/336 (54%), Gaps = 4/336 (1%)
 Frame = +2

Query: 212  KYRVVSTKSMPGTRWIKLLTDNDCRLEICTEKKTILSVDDILALIGDHCHGVIGQLTEDW 391
            K +V  T+ +P    IK+L D +  +E+  ++K I    +IL         ++  L+E  
Sbjct: 2    KPKVFITREIPEVG-IKMLED-EFEVEVWGDEKEIPR--EILLKKVKEVDALVTMLSERI 57

Query: 392  GEVLFSALKRAGGTAFSNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXX 571
             + +F    +    A  N AVGY+N+D++ A K GI + NTP VLT+ T           
Sbjct: 58   DKEVFENAPKLRIVA--NYAVGYDNIDIEEATKRGIYVTNTPDVLTDATADLAFALLLAT 115

Query: 572  XRRIVEADQFMRAGLYD----GWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKM 739
             R +V+ D+F+R+G +      W P  F+G  + G+T+G+IG GRIG A A+   +GF M
Sbjct: 116  ARHVVKGDRFVRSGEWKKRGVAWHPKWFLGYDVYGKTIGIIGLGRIGQAIAKRA-KGFNM 174

Query: 740  NLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTT 919
             ++Y+   +   +E+ + A                    +E++LRE+D + L   L + T
Sbjct: 175  RILYYSRTRKEEVERELNA----------------EFKPLEDLLRESDFVVLAVPLTRET 218

Query: 920  YHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGLA 1099
            YHLIN ERL +MKK A+L+N +RG V+D  ALV+ LK   +   GLDVFE+EPY    L 
Sbjct: 219  YHLINEERLKLMKKTAILINIARGKVVDTNALVKALKEGWIAGAGLDVFEEEPYYNEELF 278

Query: 1100 EMKNAVVVPHIASASKWTREGMATLAALNVLGKIKG 1207
            ++ N V+ PHI SAS   REGMA L A N++   +G
Sbjct: 279  KLDNVVLTPHIGSASFGAREGMAELVAKNLIAFKRG 314



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>Q9UYR1:GYAR_PYRAB Glyoxylate reductase - Pyrococcus abyssi|
          Length = 335

 Score =  183 bits (465), Expect = 2e-45
 Identities = 104/260 (40%), Positives = 149/260 (57%), Gaps = 4/260 (1%)
 Frame = +2

Query: 440  SNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLY 619
            +N AVGY+N+DV+ A K GI + NTPGVLT+ T            R +V+ D+F R+G +
Sbjct: 73   ANYAVGYDNIDVEEATKRGIYVTNTPGVLTDATADLAFALLLATARHLVKGDKFTRSGEW 132

Query: 620  D----GWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKF 787
                  W P  F+G  + G+T+G+IG GRIG A A+    GF M ++Y+   +   +EK 
Sbjct: 133  KKRGVAWHPKWFLGYDVYGKTIGIIGFGRIGQAIAKRA-RGFDMRILYYSRTRKPEVEKE 191

Query: 788  VTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEA 967
            + A                    ++E+LRE+D + L   L+K TYH+IN ERL MMK+ A
Sbjct: 192  LNA----------------EFKPLDELLRESDFVVLAVPLNKETYHMINEERLKMMKRTA 235

Query: 968  VLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASK 1147
            +L+N +RG VID  AL++ LK   +   GLDV+E+EPY    L  + N V+ PHI SA+ 
Sbjct: 236  ILINVARGKVIDTKALIKALKEGWIAGAGLDVYEEEPYYNEELFSLDNVVLTPHIGSATF 295

Query: 1148 WTREGMATLAALNVLGKIKG 1207
              REGMA L A N++   +G
Sbjct: 296  GAREGMAKLVAENLIAFKRG 315



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>Q5JEZ2:GYAR_PYRKO Glyoxylate reductase - Pyrococcus kodakaraensis (Thermococcus|
            kodakaraensis)
          Length = 333

 Score =  180 bits (456), Expect = 2e-44
 Identities = 109/280 (38%), Positives = 155/280 (55%), Gaps = 4/280 (1%)
 Frame = +2

Query: 365  VIGQLTEDWGEVLFSALKRAGGTAFSNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTXX 544
            ++  L+E     +F A  R    A  N AVGY+N+DV+ A + GI + NTP VLT+ T  
Sbjct: 49   LVTMLSERIDSEVFDAAPRLRIVA--NYAVGYDNIDVEEATRRGIYVTNTPDVLTDATAD 106

Query: 545  XXXXXXXXXXRRIVEADQFMRAGLYD----GWLPHLFVGNLLKGQTVGVIGAGRIGSAYA 712
                      RR++EAD F R+G +      W P  F+G  + G+T+G++G GRIG A A
Sbjct: 107  FAWTLLLATARRLIEADHFTRSGEWKRRGIAWHPRWFLGYDVYGKTIGIVGFGRIGQAVA 166

Query: 713  RMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADVIS 892
            R    GF M ++Y+   +    EK + A                   S+E++LRE+D + 
Sbjct: 167  RRA-RGFGMRILYYSRSRKPEAEKELGA----------------EFRSLEDLLRESDFVV 209

Query: 893  LHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFED 1072
            L   L K T ++IN ERL +MKK A+LVN +RG V+D  AL++ LK   +   GLDV+E+
Sbjct: 210  LAVPLTKETQYMINEERLRLMKKTAILVNIARGKVVDTKALMKALKEGWIAGAGLDVYEE 269

Query: 1073 EPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVL 1192
            EPY    L  +KN V+ PHI SA+   REGMA L A N++
Sbjct: 270  EPYYNEELFSLKNVVLAPHIGSATYGAREGMAELVARNLI 309



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>Q8U3Y2:GYAR_PYRFU Glyoxylate reductase - Pyrococcus furiosus|
          Length = 336

 Score =  174 bits (440), Expect = 1e-42
 Identities = 117/336 (34%), Positives = 180/336 (53%), Gaps = 4/336 (1%)
 Frame = +2

Query: 212  KYRVVSTKSMPGTRWIKLLTDNDCRLEICTEKKTILSVDDILALIGDHCHGVIGQLTEDW 391
            K +V  T+++P    I +L + +  +E+  E++ I   + +L  + D    ++  L+E  
Sbjct: 2    KPKVFITRAIP-ENGINML-EEEFEVEVWEEEREIPR-EKLLEKVKD-VDALVTMLSERI 57

Query: 392  GEVLFSALKRAGGTAFSNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXX 571
             + +F    R    A  N AVGY+N+DV+ A + GI + NTP VLT  T           
Sbjct: 58   DQEVFENAPRLRIVA--NYAVGYDNIDVEEATRRGIYVTNTPDVLTNATADHAFALLLAT 115

Query: 572  XRRIVEADQFMRAGLYD----GWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKM 739
             R +V+ D+F+R+G +      W P  F+G  L G+T+G++G GRIG A AR   +GF M
Sbjct: 116  ARHVVKGDKFVRSGEWKRKGIAWHPKWFLGYELYGKTIGIVGFGRIGQAIARRA-KGFNM 174

Query: 740  NLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTT 919
             ++Y+   + ++ EK + A                    +EEVL+E+D + L   L K T
Sbjct: 175  RILYYSRTRKSQAEKELGA----------------EYRPLEEVLKESDFVILAVPLTKET 218

Query: 920  YHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGLA 1099
             ++IN ERL +MK  A+LVN +RG V+D  AL++ LK   +   GLDVFE+EPY    L 
Sbjct: 219  MYMINEERLKLMKPTAILVNIARGKVVDTKALIKALKEGWIAGAGLDVFEEEPYYNEELF 278

Query: 1100 EMKNAVVVPHIASASKWTREGMATLAALNVLGKIKG 1207
             + N V+ PHI SA+   RE MA L A N++   +G
Sbjct: 279  SLDNVVLTPHIGSATFEAREAMAELVARNLIAFKRG 314



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>Q9YAW4:GYAR_AERPE Glyoxylate reductase - Aeropyrum pernix|
          Length = 335

 Score =  170 bits (430), Expect = 2e-41
 Identities = 104/262 (39%), Positives = 149/262 (56%), Gaps = 6/262 (2%)
 Frame = +2

Query: 440  SNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAG-- 613
            + MAVG++N+DV+ A + GI + NTPGVLTE T            RR+VEAD F+R G  
Sbjct: 73   AQMAVGFDNIDVECATRLGIYVTNTPGVLTEATAEFTWALILAAARRVVEADHFVRWGEW 132

Query: 614  --LYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKF 787
              L  GW P + +G  L+G+T+G++G GRIGS  A +  + F M +IY    +   +EK 
Sbjct: 133  WRLRTGWHPMMMLGVELRGKTLGILGMGRIGSRVAEIG-KAFGMRIIYHSRSRKREIEKE 191

Query: 788  VTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEA 967
            + A                   S+E++LRE+D++S+H  L   T HLI    L +MKK A
Sbjct: 192  LGA----------------EYRSLEDLLRESDILSIHLPLTDETRHLIGESELKLMKKTA 235

Query: 968  VLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPG--LAEMKNAVVVPHIASA 1141
            +LVN  RG ++D  ALV+ L+   +    LDVFE+EP + P   L   KN V+ PH ASA
Sbjct: 236  ILVNTGRGAIVDTGALVKALREGWIAAAALDVFEEEP-LNPNHPLTAFKNVVLAPHAASA 294

Query: 1142 SKWTREGMATLAALNVLGKIKG 1207
            ++ TR  MA +AA N++   +G
Sbjct: 295  TRETRLRMAMMAAENLVAFAQG 316



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>P37666:TKRA_ECOLI 2-ketogluconate reductase - Escherichia coli|
          Length = 324

 Score =  143 bits (360), Expect = 2e-33
 Identities = 91/259 (35%), Positives = 132/259 (50%), Gaps = 1/259 (0%)
 Frame = +2

Query: 434  AFSNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAG 613
            A S ++VGY+N DVDA     I + +TP VLTET             RR+VE  + ++AG
Sbjct: 69   ATSTISVGYDNFDVDALTARKILLMHTPTVLTETVADTLMALVLSTARRVVEVAERVKAG 128

Query: 614  LYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVT 793
             +   +   + G  +  +T+G++G GRIG A A+    GF M ++Y         E+   
Sbjct: 129  EWTASIGPDWYGTDVHHKTLGIVGMGRIGMALAQRAHFGFNMPILYNARRHHKEAEERFN 188

Query: 794  AYGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVL 973
            A                R   ++ +L+E+D + L   L   T+HL   E+ A MK  A+ 
Sbjct: 189  A----------------RYCDLDTLLQESDFVCLILPLTDETHHLFGAEQFAKMKSSAIF 232

Query: 974  VNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEPY-MKPGLAEMKNAVVVPHIASASKW 1150
            +NA RGPV+DE AL+  L+   +   GLDVFE EP  +   L  M N V VPHI SA+  
Sbjct: 233  INAGRGPVVDENALIAALQKGEIHAAGLDVFEQEPLSVDSPLLSMANVVAVPHIGSATHE 292

Query: 1151 TREGMATLAALNVLGKIKG 1207
            TR GMA  A  N++  ++G
Sbjct: 293  TRYGMAACAVDNLIDALQG 311



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>P58220:TKRA_ECO57 2-ketogluconate reductase - Escherichia coli O157:H7|
          Length = 324

 Score =  143 bits (360), Expect = 2e-33
 Identities = 91/259 (35%), Positives = 132/259 (50%), Gaps = 1/259 (0%)
 Frame = +2

Query: 434  AFSNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAG 613
            A S ++VGY+N DVDA     I + +TP VLTET             RR+VE  + ++AG
Sbjct: 69   ATSTISVGYDNFDVDALTARKILLMHTPTVLTETVADTLMALVLSTARRVVEVAERVKAG 128

Query: 614  LYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVT 793
             +   +   + G  +  +T+G++G GRIG A A+    GF M ++Y         E+   
Sbjct: 129  EWTASIGPDWYGTDVHHKTLGIVGMGRIGMALAQRAHFGFNMPILYNARRHHKEAEERFN 188

Query: 794  AYGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVL 973
            A                R   ++ +L+E+D + L   L   T+HL   E+ A MK  A+ 
Sbjct: 189  A----------------RYCDLDTLLQESDFVCLILPLTDETHHLFGAEQFAKMKSSAIF 232

Query: 974  VNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEPY-MKPGLAEMKNAVVVPHIASASKW 1150
            +NA RGPV+DE AL+  L+   +   GLDVFE EP  +   L  M N V VPHI SA+  
Sbjct: 233  INAGRGPVVDENALIAALQKGEIHAAGLDVFEQEPLSVDSPLLSMANVVAVPHIGSATHE 292

Query: 1151 TREGMATLAALNVLGKIKG 1207
            TR GMA  A  N++  ++G
Sbjct: 293  TRYGMAACAVDNLIDALQG 311



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>P58000:TKRA_ENTAG 2-ketogluconate reductase - Enterobacter agglomerans (Erwinia|
            herbicola) (Pantoea agglomerans)
          Length = 323

 Score =  142 bits (359), Expect = 3e-33
 Identities = 91/259 (35%), Positives = 136/259 (52%), Gaps = 1/259 (0%)
 Frame = +2

Query: 434  AFSNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAG 613
            A S ++VGY+N DV+A N+ GI + +TP VLTET             RR+VE  + ++AG
Sbjct: 68   AASTISVGYDNFDVEALNQRGIVLIDTPTVLTETVADTMMALVLSSARRVVEVAERVKAG 127

Query: 614  LYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVT 793
             +   +   + G  +  + +G++G GRIG A A+    GF M ++Y         E    
Sbjct: 128  EWRRSIGPDWFGIDVHHKKMGILGMGRIGLALAQRAHHGFGMPILYNARKHHEEAESRFN 187

Query: 794  AYGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVL 973
            A                +   ++ +LRE+D + +   L + T+H+I  E+LA MK  A+L
Sbjct: 188  A----------------QYCDLDTLLRESDFLCISLPLTEQTHHMIGREQLAKMKPSAIL 231

Query: 974  VNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEPY-MKPGLAEMKNAVVVPHIASASKW 1150
            +NA RGPV+DE AL+  LK   +   GLDVFE EP  +   L  + N V +PHI SA+  
Sbjct: 232  INAGRGPVVDEQALIAALKDKTIHAAGLDVFEQEPLPVDSELLTLPNVVALPHIGSATHE 291

Query: 1151 TREGMATLAALNVLGKIKG 1207
            TR GMA  A  N++  + G
Sbjct: 292  TRYGMARDAVDNLIAALAG 310



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>O32264:TKRA_BACSU Probable 2-ketogluconate reductase - Bacillus subtilis|
          Length = 325

 Score =  142 bits (357), Expect = 5e-33
 Identities = 96/317 (30%), Positives = 145/317 (45%), Gaps = 23/317 (7%)
 Frame = +2

Query: 326  DDILALIGDHCHGVIGQLTEDWGEVLFSALKRAGGT----------------------AF 439
            ++I A IG+HC   + Q      +VLF  LK A G                         
Sbjct: 14   EEIEAFIGEHCRYEVWQEDTLPSDVLFEKLKEAEGLLTSGTSGPSINRELLEHAPKLKVV 73

Query: 440  SNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLY 619
            SN +VGY+N D++A  + G+   +TP  L +T             RR+ E D+F+RAG +
Sbjct: 74   SNQSVGYDNFDIEAMKERGVVGTHTPYTLDDTVADLAFSLILSSARRVAELDRFVRAGKW 133

Query: 620  DGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAY 799
                     G  +  QT+G+IG GRIG   AR    GF M ++Y + ++    E  +   
Sbjct: 134  GTVEEEALFGIDVHHQTLGIIGMGRIGEQAARRAKFGFDMEVLYHNRHRKQETEDSIGV- 192

Query: 800  GQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVN 979
                           + + ++ +L ++D I L   L   TYH+I      +MK  A+ VN
Sbjct: 193  ---------------KYAELDTLLEQSDFILLITPLTDETYHMIGEREFKLMKNSAIFVN 237

Query: 980  ASRGPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPG-LAEMKNAVVVPHIASASKWTR 1156
             SRG  +DE AL+  L+   +   GLDV+E EP  +   L ++ N  ++PHI SA+   R
Sbjct: 238  ISRGKTVDEKALIRALQEGWIRGAGLDVYEKEPVTQDNPLLQLDNVTLLPHIGSATAKVR 297

Query: 1157 EGMATLAALNVLGKIKG 1207
              M   AA N+L  I+G
Sbjct: 298  FNMCKQAAENMLAAIQG 314



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>O27051:SERA_METTH D-3-phosphoglycerate dehydrogenase - Methanobacterium|
            thermoautotrophicum
          Length = 525

 Score =  129 bits (324), Expect = 3e-29
 Identities = 109/336 (32%), Positives = 166/336 (49%), Gaps = 3/336 (0%)
 Frame = +2

Query: 311  TILSVDDILALIGDHCHGVIGQLTEDWGEVLFSALKRAGGTAFSNMAVGYNNVDVDAANK 490
            T ++ +++L  I D    V+   T+   EV+ +A +       +   VG +NVDV AA  
Sbjct: 30   TTITPEELLDAIKDFDAIVVRSRTKVTREVIEAAPRLK---IIARAGVGVDNVDVKAATD 86

Query: 491  NGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLPHLFVGNLLKGQT 670
             GI + N P   + T             R+I  AD+ ++ G    W  + F+G  L G+T
Sbjct: 87   RGIMVINAPESTSITVAEHSIGLMLALARKIAIADRSVKEGK---WEKNRFMGIELNGKT 143

Query: 671  VGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRA 850
            +G+IG GRIGS    +  + F M+++ +D Y S              +A  E  VT    
Sbjct: 144  LGIIGMGRIGSQVV-VRTKAFGMDIMVYDPYISK-------------EAAEEMGVT---V 186

Query: 851  SSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLK 1030
            + +E +LRE+D++++H  L   T HLI+ +   +MK  A +VN +RG +IDE AL   LK
Sbjct: 187  TDLETLLRESDIVTIHVPLTPETRHLISEDEFKLMKDTAFIVNCARGGIIDEDALYRALK 246

Query: 1031 ANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHI-ASASKWTREGMATLAALNVLGKIKG 1207
               +    LDVFE+EP     L E++N V+ PHI AS S+  R+     AA+ V  +IK 
Sbjct: 247  DGEIAGAALDVFEEEPPEGSPLLELENVVLTPHIGASTSEAQRD-----AAIIVANEIKT 301

Query: 1208 YPVWGNPNAV--EPFLDEEATPPPACPSIVNAKQLG 1309
                G P  V   P +D E T     P I  A+++G
Sbjct: 302  VFQGGAPRNVLNMPVMDSE-TYKSLKPYIELAEKMG 336



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>Q9UBQ7:GRHPR_HUMAN Glyoxylate reductase/hydroxypyruvate reductase - Homo sapiens (Human)|
          Length = 328

 Score =  125 bits (313), Expect = 7e-28
 Identities = 99/334 (29%), Positives = 155/334 (46%), Gaps = 1/334 (0%)
 Frame = +2

Query: 218  RVVSTKSMPGTRWIKLLTDNDCRLEICTEKKTILSVDDILALIGDHCHGVIGQLTEDWGE 397
            +V  T+ +P    + L    DC +E     + I + +    + G   HG++  L++   +
Sbjct: 8    KVFVTRRIPAEGRVALARAADCEVEQWDSDEPIPAKELERGVAG--AHGLLCLLSDHVDK 65

Query: 398  VLFSALKRAGGTAFSNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXR 577
             +  A   A     S M+VG +++ +D   K GI +G TP VLT+TT            R
Sbjct: 66   RILDAAG-ANLKVISTMSVGIDHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLLTTCR 124

Query: 578  RIVEADQFMRAGLYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFD 757
            R+ EA + ++ G +  W P    G  L   TVG+IG GRIG A AR +        +Y  
Sbjct: 125  RLPEAIEEVKNGGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTG 184

Query: 758  LYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINP 937
              +  R E+      +F+              S  E+  ++D I +   L   T  L N 
Sbjct: 185  --RQPRPEEAAEFQAEFV--------------STPELAAQSDFIVVACSLTPATEGLCNK 228

Query: 938  ERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEPY-MKPGLAEMKNA 1114
            +    MK+ AV +N SRG V+++  L + L +  +   GLDV   EP      L  +KN 
Sbjct: 229  DFFQKMKETAVFINISRGDVVNQDDLYQALASGKIAAAGLDVTSPEPLPTNHPLLTLKNC 288

Query: 1115 VVVPHIASASKWTREGMATLAALNVLGKIKGYPV 1216
            V++PHI SA+  TR  M+ LAA N+L  ++G P+
Sbjct: 289  VILPHIGSATHRTRNTMSLLAANNLLAGLRGEPM 322



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>O29445:SERA_ARCFU D-3-phosphoglycerate dehydrogenase - Archaeoglobus fulgidus|
          Length = 527

 Score =  122 bits (307), Expect = 3e-27
 Identities = 95/319 (29%), Positives = 158/319 (49%), Gaps = 5/319 (1%)
 Frame = +2

Query: 302  EKKTILSVDDILALIGDHCHGVIGQLTEDWGEVLFSA--LKRAGGTAFSNMAVGYNNVDV 475
            E KT +S ++++  +  +   V+   T+   EV+ +A  LK  G        VG +N+D+
Sbjct: 25   EVKTGMSREELIREVPKYEAIVVRSQTKVDAEVIQAAKNLKIIG-----RAGVGVDNIDI 79

Query: 476  DAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLPHLFVGNL 655
            +AA + GI + N PG  T +T            R+I +AD+ ++ G    W    F+G  
Sbjct: 80   NAATQRGIVVVNAPGGNTISTAEHAIALMLAAARKIPQADRSVKEGK---WERKKFMGIE 136

Query: 656  LKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPV 835
            L+G+T GVIG GR+G   A+   +  +MN++ +D + S              K   EQ  
Sbjct: 137  LRGKTAGVIGLGRVGFEVAKRC-KALEMNVLAYDPFVS--------------KERAEQ-- 179

Query: 836  TWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVAL 1015
               +    + +L  +DVI++H    K T  LI   +   MK   ++VNA+RG ++DE AL
Sbjct: 180  IGVKLVDFDTLLASSDVITVHVPRTKETIGLIGKGQFEKMKDGVIVVNAARGGIVDEAAL 239

Query: 1016 VEHLKANPMFRVGLDVFEDEPYMKPG-LAEMKNAVVVPHIASASKWTREGMATLAALNVL 1192
             E +KA  +    LDV+E EP      L ++ N V  PHIA++++  +  +  + A +++
Sbjct: 240  YEAIKAGKVAAAALDVYEKEPPSPDNPLLKLDNVVTTPHIAASTREAQLNVGMIIAEDIV 299

Query: 1193 GKIKGYPVWGNPN--AVEP 1243
               KG PV    N  ++EP
Sbjct: 300  NMAKGLPVRNAVNLPSIEP 318



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>O04130:SERA_ARATH D-3-phosphoglycerate dehydrogenase, chloroplast precursor -|
            Arabidopsis thaliana (Mouse-ear cress)
          Length = 624

 Score =  121 bits (304), Expect = 7e-27
 Identities = 115/379 (30%), Positives = 173/379 (45%), Gaps = 8/379 (2%)
 Frame = +2

Query: 197  WNPS-GKYRVVSTKSM--PGTRWIKLLTDNDCRLEICTE--KKTILSVDDILALIGDHCH 361
            +NP+  K R++ T+ +   G   ++   D DC  ++  E  KK +   D ++   G    
Sbjct: 76   YNPTLPKPRILVTEKLGEAGVNLLREFGDVDCSYDLSPEDLKKKVAESDALIVRSGT--- 132

Query: 362  GVIGQLTEDWGEVLFSALKRAGGTAFSNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTX 541
                ++T +  E     LK  G        VG +NVD+ AA ++G  + N P   T    
Sbjct: 133  ----KVTREVFEAAKGRLKVVG-----RAGVGIDNVDLQAATEHGCLVVNAPTANTVAAA 183

Query: 542  XXXXXXXXXXXRRIVEADQFMRAGLYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMM 721
                       R + +AD  ++AG    W    +VG  L G+T+ V+G G++G+  AR  
Sbjct: 184  EHGIALLASMARNVAQADASIKAGK---WERSKYVGVSLVGKTLAVMGFGKVGTEVARRA 240

Query: 722  IEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLHP 901
             +G  M +I  D Y          A     +A G   V      S ++ +  AD +SLH 
Sbjct: 241  -KGLGMTVISHDPY----------APADRARALGVDLV------SFDQAISTADFVSLHM 283

Query: 902  VLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEPY 1081
             L   T  + N E  + MKK   L+N +RG VIDE ALV  L A  + +  LDVF +EP 
Sbjct: 284  PLTPATKKVFNDETFSKMKKGVRLINVARGGVIDEDALVRALDAGIVAQAALDVFCEEPP 343

Query: 1082 MKPG-LAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKGYPVWGNPNA--VEPFLD 1252
             K   L + +N  V PH+ +++K  +EG+A   A  V G +KG       NA  V P + 
Sbjct: 344  SKDSRLIQHENVTVTPHLGASTKEAQEGVAIEIAEAVAGALKGELSATAVNAPMVAPEVL 403

Query: 1253 EEATPPPACPSIVNAKQLG 1309
             E T     P IV A++LG
Sbjct: 404  SELT-----PYIVLAEKLG 417



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>Q91Z53:GRHPR_MOUSE Glyoxylate reductase/hydroxypyruvate reductase - Mus musculus (Mouse)|
          Length = 328

 Score =  120 bits (302), Expect = 1e-26
 Identities = 102/343 (29%), Positives = 153/343 (44%), Gaps = 8/343 (2%)
 Frame = +2

Query: 203  PSGKYRVVSTKSMPGTRWIKLLTDNDCRLEICTEKKTILSVDDILALIGDHCHGVIGQLT 382
            P+   +V  T  +P      L    DC +E       I   D    ++G   HG++ +L+
Sbjct: 3    PARLMKVFVTGPLPAEGRAALAQAADCEVEQWNSDDPIPRKDLEQGVVG--AHGLLCRLS 60

Query: 383  EDWGEVLFSALKRAGGTAFSNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXX 562
            +   + L  A   A     S ++VG +++ +D   K GI +G TPGVLT+ T        
Sbjct: 61   DRVDKKLLDAAG-ANLRVISTLSVGVDHLALDEIKKRGIRVGYTPGVLTDATAELAVSLL 119

Query: 563  XXXXRRIVEADQFMRAGLYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMN 742
                RR+ EA + ++ G +  W P    G  L   TVG++G GRIG A AR         
Sbjct: 120  LTTCRRLPEAIEEVKNGGWSSWSPLWMCGYGLSQSTVGIVGLGRIGQAIAR--------- 170

Query: 743  LIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEE------VLREADVISLHPV 904
                      RL+ F     Q     G QP   + A    E      +  E+D I +   
Sbjct: 171  ----------RLKPFGV---QRFLYTGRQPRPQEAAEFQAEFVPIAQLAAESDFIVVSCS 217

Query: 905  LDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEPYM 1084
            L   T  L + +    MK  A+ +N SRG V+++  L + L +  +   GLDV   EP +
Sbjct: 218  LTPDTMGLCSKDFFQKMKNTAIFINISRGDVVNQEDLYQALASGQIAAAGLDVTTPEP-L 276

Query: 1085 KPG--LAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKG 1207
             P   L  +KN V++PHI SA+  TR  M+ LAA N+L  ++G
Sbjct: 277  PPSHPLLTLKNCVILPHIGSATYKTRNTMSLLAANNLLAGLRG 319



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>P35136:SERA_BACSU D-3-phosphoglycerate dehydrogenase - Bacillus subtilis|
          Length = 525

 Score =  119 bits (299), Expect = 3e-26
 Identities = 85/274 (31%), Positives = 131/274 (47%)
 Frame = +2

Query: 452  VGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWL 631
            VG +N+D+D A K+G+ + N P   T +T            R I +A+  +++     W 
Sbjct: 71   VGVDNIDIDEATKHGVIVINAPNGNTISTAEHTFAMISSLMRHIPQANISVKSR---EWN 127

Query: 632  PHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFL 811
               +VG+ L G+T+G++G GRIGS  A+     F M +  FD + +    K +       
Sbjct: 128  RTAYVGSELYGKTLGIVGLGRIGSEIAQRR-GAFGMTVHVFDPFLTEERAKKIGV----- 181

Query: 812  KANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRG 991
                        + + EEVL  AD+I++H  L K T  L+N E +A  KK   L+N +RG
Sbjct: 182  -----------NSRTFEEVLESADIITVHTPLTKETKGLLNKETIAKTKKGVRLINCARG 230

Query: 992  PVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMAT 1171
             +IDE AL+E L+   +    LDVFE EP +   L +    +  PH+ +++K  +  +A 
Sbjct: 231  GIIDEAALLEALENGHVAGAALDVFEVEPPVDNKLVDHPLVIATPHLGASTKEAQLNVAA 290

Query: 1172 LAALNVLGKIKGYPVWGNPNAVEPFLDEEATPPP 1273
              +  VL   KG PV    N      DE A   P
Sbjct: 291  QVSEEVLQFAKGLPVMSAINLPAMTKDEFAKIKP 324



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>Q58424:SERA_METJA D-3-phosphoglycerate dehydrogenase - Methanococcus jannaschii|
          Length = 524

 Score =  118 bits (295), Expect = 8e-26
 Identities = 88/302 (29%), Positives = 143/302 (47%)
 Frame = +2

Query: 302  EKKTILSVDDILALIGDHCHGVIGQLTEDWGEVLFSALKRAGGTAFSNMAVGYNNVDVDA 481
            E  T L+ +++L  I D    V+   T+   +V+  A K           VG +N+DV+A
Sbjct: 25   EVATGLTKEELLEKIKDADVLVVRSGTKVTRDVIEKAEKLK---VIGRAGVGVDNIDVEA 81

Query: 482  ANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLPHLFVGNLLK 661
            A + GI + N P   + +             R I +A   ++ G +D      F G  L 
Sbjct: 82   ATEKGIIVVNAPDASSISVAELTMGLMLAAARNIPQATASLKRGEWDR---KRFKGIELY 138

Query: 662  GQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTW 841
            G+T+GVIG GRIG    +   + F MN+I +D Y    + + +                 
Sbjct: 139  GKTLGVIGLGRIGQQVVKRA-KAFGMNIIGYDPYIPKEVAESMGV--------------- 182

Query: 842  KRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVE 1021
            +    + E+ + AD I+LH  L   T H+I  E++A+MKK A++VN +RG +IDE AL E
Sbjct: 183  ELVDDINELCKRADFITLHVPLTPKTRHIIGREQIALMKKNAIIVNCARGGLIDEKALYE 242

Query: 1022 HLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKI 1201
             LK   +    LDVFE+EP     L  + N +  PH  ++++  ++   T+ A  +   +
Sbjct: 243  ALKEGKIRAAALDVFEEEPPKDNPLLTLDNVIGTPHQGASTEEAQKAAGTIVAEQIKKVL 302

Query: 1202 KG 1207
            +G
Sbjct: 303  RG 304



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>P36234:DHGY_HYPME Glycerate dehydrogenase - Hyphomicrobium methylovorum|
          Length = 322

 Score =  117 bits (293), Expect = 1e-25
 Identities = 80/299 (26%), Positives = 138/299 (46%), Gaps = 1/299 (0%)
 Frame = +2

Query: 275  NDCRLEICTEKKTILSVDDILALIGDHCHG-VIGQLTEDWGEVLFSALKRAGGTAFSNMA 451
            +D ++ I    +T  SVD +L  + + C   VI ++ E+                 S  +
Sbjct: 31   DDPKITIDEMIETAKSVDALLITLNEKCRKEVIDRIPENI-------------KCISTYS 77

Query: 452  VGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWL 631
            +G++++D+DA    GI +GN P  +T  T            RR  E ++ +R   + GW 
Sbjct: 78   IGFDHIDLDACKARGIKVGNAPHGVTVATAEIAMLLLLGSARRAGEGEKMIRTRSWPGWE 137

Query: 632  PHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFL 811
            P   VG  L  +T+G+ G G IG A A+   +GF M++ YFD ++++             
Sbjct: 138  PLELVGEKLDNKTLGIYGFGSIGQALAK-RAQGFDMDIDYFDTHRAS------------- 183

Query: 812  KANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRG 991
             ++ E         S++ +L  +   SL+      T +  N   +  + + A++VN +RG
Sbjct: 184  -SSDEASYQATFHDSLDSLLSVSQFFSLNAPSTPETRYFFNKATIKSLPQGAIVVNTARG 242

Query: 992  PVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA 1168
             ++D   +V  L+A  +   G DVF  EP +  G  ++ N  + PHI SA+   RE MA
Sbjct: 243  DLVDNELVVAALEAGRLAYAGFDVFAGEPNINEGYYDLPNTFLFPHIGSAATQAREDMA 301



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>O33116:SERA_MYCLE D-3-phosphoglycerate dehydrogenase - Mycobacterium leprae|
          Length = 528

 Score =  112 bits (280), Expect = 4e-24
 Identities = 85/272 (31%), Positives = 124/272 (45%)
 Frame = +2

Query: 452  VGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWL 631
            VG +NVDVDAA   G+ + N P     +             R+I EAD  +RA +   W 
Sbjct: 74   VGLDNVDVDAATARGVLVVNAPTSNIHSAAEHALALLLAASRQIAEADASLRAHI---WK 130

Query: 632  PHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFL 811
               F G  + G+TVGV+G GRIG   A   I  F  ++I +D Y                
Sbjct: 131  RSSFSGTEIFGKTVGVVGLGRIGQLVAAR-IAAFGAHVIAYDPYV--------------- 174

Query: 812  KANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRG 991
             A            S +++L  AD IS+H      T  LI+ E LA  K   ++VNA+RG
Sbjct: 175  -APARAAQLGIELMSFDDLLARADFISVHLPKTPETAGLIDKEALAKTKPGVIIVNAARG 233

Query: 992  PVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMAT 1171
             ++DEVAL + +++  +   GLDVF  EP     L E+   VV PH+ +++   ++   T
Sbjct: 234  GLVDEVALADAVRSGHVRAAGLDVFATEPCTDSPLFELSQVVVTPHLGASTAEAQDRAGT 293

Query: 1172 LAALNVLGKIKGYPVWGNPNAVEPFLDEEATP 1267
              A +V   + G  V    N     ++EE  P
Sbjct: 294  DVAESVRLALAGEFVPDAVNVDGGVVNEEVAP 325



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>O69054:PTXD_PSEST Phosphonate dehydrogenase - Pseudomonas stutzeri (Pseudomonas|
            perfectomarina)
          Length = 336

 Score =  107 bits (267), Expect = 1e-22
 Identities = 79/259 (30%), Positives = 120/259 (46%), Gaps = 8/259 (3%)
 Frame = +2

Query: 455  GYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLP 634
            G++N DVDA    G+ +   P +LT  T            R +  AD F+R+G + GW P
Sbjct: 77   GFDNFDVDACTARGVWLTFVPDLLTVPTAELAIGLAVGLGRHLRAADAFVRSGEFQGWQP 136

Query: 635  HLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLK 814
              F G  L   TVG++G G IG A A  + +G+   L Y +               + L 
Sbjct: 137  Q-FYGTGLDNATVGILGMGAIGLAMADRL-QGWGATLQYHE--------------AKALD 180

Query: 815  ANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGP 994
               EQ +  ++ +   E+   +D I L   L+  T HL+N E LA+++  A+LVN  RG 
Sbjct: 181  TQTEQRLGLRQVAC-SELFASSDFILLALPLNADTQHLVNAELLALVRPGALLVNPCRGS 239

Query: 995  VIDEVALVEHLKANPMFRVGLDVFEDEPYMK--------PGLAEMKNAVVVPHIASASKW 1150
            V+DE A++  L+   +     DVFE E + +        P L    N +  PHI SA + 
Sbjct: 240  VVDEAAVLAALERGQLGGYAADVFEMEDWARADRPRLIDPALLAHPNTLFTPHIGSAVRA 299

Query: 1151 TREGMATLAALNVLGKIKG 1207
             R  +   AA N++  + G
Sbjct: 300  VRLEIERCAAQNIIQVLAG 318



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>P53839:YN14_YEAST Putative 2-hydroxyacid dehydrogenase YNL274C - Saccharomyces|
            cerevisiae (Baker's yeast)
          Length = 350

 Score =  105 bits (263), Expect = 4e-22
 Identities = 83/288 (28%), Positives = 130/288 (45%), Gaps = 3/288 (1%)
 Frame = +2

Query: 434  AFSNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAG 613
            A  +   GY+ +DV+   K  I + N P +++  T            R     ++ +  G
Sbjct: 85   AVCHTGAGYDQIDVEPFKKRHIQVANVPDLVSNATADTHVFLLLGALRNFGIGNRRLIEG 144

Query: 614  LYDGWLPHLF--VGNLLKGQTVGVIGAGRIGSAYA-RMMIEGFKMNLIYFDLYQSTRLEK 784
             +    P      G   +G+TVG++G GRIG     R+   GF+ N IY + +Q    E+
Sbjct: 145  NWPEAGPACGSPFGYDPEGKTVGILGLGRIGRCILERLKPFGFE-NFIYHNRHQLPSEEE 203

Query: 785  FVTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKE 964
                Y  F                 EE L+ +D++S++  L+  T+HLIN E +  MK  
Sbjct: 204  HGCEYVGF-----------------EEFLKRSDIVSVNVPLNHNTHHLINAETIEKMKDG 246

Query: 965  AVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASAS 1144
             V+VN +RG VIDE A+ + L++  +   GLDVFE EP +   L  M   + +PH+ + S
Sbjct: 247  VVIVNTARGAVIDEQAMTDALRSGKIRSAGLDVFEYEPKISKELLSMSQVLGLPHMGTHS 306

Query: 1145 KWTREGMATLAALNVLGKIKGYPVWGNPNAVEPFLDEEATPPPACPSI 1288
              TR+ M  L   N     K   + G    + P L  E  P  + P +
Sbjct: 307  VETRKKMEELVVENA----KNVILTGKVLTIVPELQNEDWPNESKPLV 350



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>O43175:SERA_HUMAN D-3-phosphoglycerate dehydrogenase - Homo sapiens (Human)|
          Length = 533

 Score =  105 bits (263), Expect = 4e-22
 Identities = 86/311 (27%), Positives = 144/311 (46%), Gaps = 1/311 (0%)
 Frame = +2

Query: 305  KKTILSVDDILALIGDHCHG-VIGQLTEDWGEVLFSALKRAGGTAFSNMAVGYNNVDVDA 481
            +K  LS ++++A + D C G ++   T+   +V+ +A K            G +NVD++A
Sbjct: 32   EKQNLSKEELIAELQD-CEGLIVRSATKVTADVINAAEKLQ---VVGRAGTGVDNVDLEA 87

Query: 482  ANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLPHLFVGNLLK 661
            A + GI + NTP   + +             R+I +A   M+ G    W    F+G  L 
Sbjct: 88   ATRKGILVMNTPNGNSLSAAELTCGMIMCLARQIPQATASMKDGK---WERKKFMGTELN 144

Query: 662  GQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTW 841
            G+T+G++G GRIG   A  M + F M  I +D   S  +            + G Q +  
Sbjct: 145  GKTLGILGLGRIGREVATRM-QSFGMKTIGYDPIISPEVSA----------SFGVQQLP- 192

Query: 842  KRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVE 1021
                 +EE+    D I++H  L  +T  L+N    A  KK   +VN +RG ++DE AL+ 
Sbjct: 193  -----LEEIWPLCDFITVHTPLLPSTTGLLNDNTFAQCKKGVRVVNCARGGIVDEGALLR 247

Query: 1022 HLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKI 1201
             L++       LDVF +EP     L + +N +  PH+ +++K  +       A+  +  +
Sbjct: 248  ALQSGQCAGAALDVFTEEPPRDRALVDHENVISCPHLGASTKEAQSRCGEEIAVQFVDMV 307

Query: 1202 KGYPVWGNPNA 1234
            KG  + G  NA
Sbjct: 308  KGKSLTGVVNA 318



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>Q61753:SERA_MOUSE D-3-phosphoglycerate dehydrogenase - Mus musculus (Mouse)|
          Length = 533

 Score =  105 bits (262), Expect = 5e-22
 Identities = 84/311 (27%), Positives = 145/311 (46%), Gaps = 1/311 (0%)
 Frame = +2

Query: 305  KKTILSVDDILALIGDHCHG-VIGQLTEDWGEVLFSALKRAGGTAFSNMAVGYNNVDVDA 481
            +K  LS ++++A + D C G ++   T+   +V+ +A K            G +NVD++A
Sbjct: 32   EKQNLSKEELIAELQD-CEGLIVRSATKVTADVINAAEKLQ---VVGRAGTGVDNVDLEA 87

Query: 482  ANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLPHLFVGNLLK 661
            A + GI + NTP   + +             R+I +A   M+ G +D      F+G  L 
Sbjct: 88   ATRKGILVMNTPNGNSLSAAELTCGMIMCLARQIPQATASMKDGKWDR---KKFMGTELN 144

Query: 662  GQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTW 841
            G+T+G++G GRIG   A  M + F M  + +D   S  +     ++G             
Sbjct: 145  GKTLGILGLGRIGREVATRM-QSFGMKTVGYDPIISPEV---AASFGV------------ 188

Query: 842  KRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVE 1021
             +   +EE+    D I++H  L  +T  L+N    A  KK   +VN +RG ++DE AL+ 
Sbjct: 189  -QQLPLEEIWPLCDFITVHTPLLPSTTGLLNDSTFAQCKKGVRVVNCARGGIVDEGALLR 247

Query: 1022 HLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKI 1201
             L++       LDVF +EP     L + +N +  PH+ +++K  +       A+  +  +
Sbjct: 248  ALQSGQCAGAALDVFTEEPPRDRALVDHENVISCPHLGASTKEAQSRCGEEIAVQFVDMV 307

Query: 1202 KGYPVWGNPNA 1234
            KG  + G  NA
Sbjct: 308  KGKSLTGVVNA 318



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>Q9W758:CTBP2_XENLA C-terminal-binding protein 2 - Xenopus laevis (African clawed frog)|
          Length = 437

 Score =  105 bits (262), Expect = 5e-22
 Identities = 87/313 (27%), Positives = 145/313 (46%), Gaps = 14/313 (4%)
 Frame = +2

Query: 239  MPGTRWIKLLTDNDCRLEICTEKKTILSVDDILALIGDHCHGVIGQLTEDWGEVLFSA-- 412
            MP    + LL   DC +E+    K + +V    A      H  +  L+E  G +++    
Sbjct: 27   MPVRPLVALLDGRDCTIEMPI-LKDVATVAFCDAQSTQEIHEKV--LSEAVGALMYHTIT 83

Query: 413  LKRAGGTAFSNMAV------GYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXX 574
            L R     F  + +      GY+N+D+ +A + GIA+ N P    E T            
Sbjct: 84   LSREDLEKFKALRIIIKIGSGYDNIDIKSAAELGIAVCNIPSASVEETADSTLCHILNLY 143

Query: 575  RRIVEADQFMRAGLYDGWLPHL--FVGNL--LKGQTVGVIGAGRIGSAYARMMIEGFKMN 742
            RR+    Q MR G     +  +    G    ++G+T+G+IG GRIG A A +  + F   
Sbjct: 144  RRVTWLHQAMREGNRPASVEQIREVAGGAARIRGETLGIIGLGRIGQAVA-LRAKAFNFT 202

Query: 743  LIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTY 922
            +I++D Y +  +E+ +                 +R ++++E+L  +D I+LH  L++  +
Sbjct: 203  VIFYDPYLADGVERSLGL---------------QRMATLQELLMHSDCITLHCNLNEHNH 247

Query: 923  HLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEP--YMKPGL 1096
            HLIN   +  M++   LVN +RG ++DE AL + LK   +    LDV E EP  + +  L
Sbjct: 248  HLINDFTIKQMRQGCFLVNTARGGLVDEKALAQALKDGRIRGAALDVHESEPFSFSQGPL 307

Query: 1097 AEMKNAVVVPHIA 1135
             +  N +  PH A
Sbjct: 308  KDAPNLICTPHTA 320



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>O08651:SERA_RAT D-3-phosphoglycerate dehydrogenase - Rattus norvegicus (Rat)|
          Length = 533

 Score =  105 bits (261), Expect = 7e-22
 Identities = 83/311 (26%), Positives = 145/311 (46%), Gaps = 1/311 (0%)
 Frame = +2

Query: 305  KKTILSVDDILALIGDHCHG-VIGQLTEDWGEVLFSALKRAGGTAFSNMAVGYNNVDVDA 481
            +K  LS ++++A + D C G ++   T+   +V+ +A K            G +NVD++A
Sbjct: 32   EKQNLSKEELIAELQD-CEGLIVRSATKVTADVINAAEKLQ---VVGRAGTGVDNVDLEA 87

Query: 482  ANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLPHLFVGNLLK 661
            A + G+ + NTP   + +             R+I +A   M+ G +D      F+G  L 
Sbjct: 88   ATRKGVLVMNTPNGNSLSAAELTCGMLMCLARQIPQATASMKDGKWDR---KKFMGTELN 144

Query: 662  GQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTW 841
            G+T+G++G GRIG   A  M + F M  + +D   S  +     ++G             
Sbjct: 145  GKTLGILGLGRIGREVAARM-QAFGMKTVGYDPIISPEV---AASFGV------------ 188

Query: 842  KRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVE 1021
             +   +EE+    D I++H  L  +T  L+N    A  KK   +VN +RG ++DE AL+ 
Sbjct: 189  -QQLPLEEIWPLCDFITVHTPLLPSTTGLLNDSTFAQCKKGVRVVNCARGGIVDEGALLR 247

Query: 1022 HLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKI 1201
             L++       LDVF +EP     L + +N +  PH+ +++K  +       A+  +  +
Sbjct: 248  ALQSGQCAGAALDVFTEEPPRDRALVDHENVISCPHLGASTKEAQSRCGEEIAVQFVDMV 307

Query: 1202 KGYPVWGNPNA 1234
            KG  + G  NA
Sbjct: 308  KGKSLTGVVNA 318



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>Q60HD7:SERA_MACFA D-3-phosphoglycerate dehydrogenase - Macaca fascicularis (Crab eating|
            macaque) (Cynomolgus monkey)
          Length = 533

 Score =  105 bits (261), Expect = 7e-22
 Identities = 85/311 (27%), Positives = 144/311 (46%), Gaps = 1/311 (0%)
 Frame = +2

Query: 305  KKTILSVDDILALIGDHCHG-VIGQLTEDWGEVLFSALKRAGGTAFSNMAVGYNNVDVDA 481
            +K  LS ++++A + D C G ++   T+   +V+ +A K            G +NVD++A
Sbjct: 32   EKQNLSKEELIAELQD-CEGLIVRSATKVTADVINAAEKLQ---VVGRAGTGVDNVDLEA 87

Query: 482  ANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLPHLFVGNLLK 661
            A + G+ + NTP   + +             R+I +A   M+ G    W    F+G  L 
Sbjct: 88   ATRKGVLVMNTPNGNSLSAAELTCGMIMCLARQIPQATASMKDGK---WERKKFMGTELN 144

Query: 662  GQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTW 841
            G+T+G++G GRIG   A  M + F M  I +D   S  +            + G Q +  
Sbjct: 145  GKTLGILGLGRIGREVATRM-QSFGMKTIGYDPIISPEVSA----------SFGVQQLP- 192

Query: 842  KRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVE 1021
                 +EE+    D I++H  L  +T  L+N    A  KK   +VN +RG ++DE AL+ 
Sbjct: 193  -----LEEIWPLCDFITVHTPLLPSTTGLLNDNTFAQCKKGVRVVNCARGGIVDEGALLR 247

Query: 1022 HLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKI 1201
             L++       LDVF +EP     L + +N +  PH+ +++K  +       A+  +  +
Sbjct: 248  ALQSGQCAGAALDVFTEEPPRDRALVDHENVISCPHLGASTKEAQSRCGEEIAVQFVDMV 307

Query: 1202 KGYPVWGNPNA 1234
            KG  + G  NA
Sbjct: 308  KGKSLAGVVNA 318



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>P56545:CTBP2_HUMAN C-terminal-binding protein 2 - Homo sapiens (Human)|
          Length = 445

 Score =  105 bits (261), Expect = 7e-22
 Identities = 91/315 (28%), Positives = 145/315 (46%), Gaps = 26/315 (8%)
 Frame = +2

Query: 455  GYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLP 634
            GY+NVD+ AA + GIA+ N P    E T            RR     Q +R G     + 
Sbjct: 107  GYDNVDIKAAGELGIAVCNIPSAAVEETADSTICHILNLYRRNTWLYQALREGTRVQSVE 166

Query: 635  HLFV----GNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYG 802
             +         ++G+T+G+IG GR G A A +  + F  ++I++D Y    +E+ +    
Sbjct: 167  QIREVASGAARIRGETLGLIGFGRTGQAVA-VRAKAFGFSVIFYDPYLQDGIERSLGV-- 223

Query: 803  QFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNA 982
                         +R  +++++L ++D +SLH  L++  +HLIN   +  M++ A LVNA
Sbjct: 224  -------------QRVYTLQDLLYQSDCVSLHCNLNEHNHHLINDFTIKQMRQGAFLVNA 270

Query: 983  SRGPVIDEVALVEHLKANPMFRVGLDVFEDEP--YMKPGLAEMKNAVVVPHIA----SAS 1144
            +RG ++DE AL + LK   +    LDV E EP  + +  L +  N +  PH A     AS
Sbjct: 271  ARGGLVDEKALAQALKEGRIRGAALDVHESEPFSFAQGPLKDAPNLICTPHTAWYSEQAS 330

Query: 1145 KWTREGMATLAALNVLGKI---------KGYPVWGNPNAVEPFLDEEATPPPA------- 1276
               RE  AT     + G+I         K + V   P +V   +D++A  P         
Sbjct: 331  LEMREAAATEIRRAITGRIPESLRNCVNKEFFVTSAPWSV---IDQQAIHPELNGATYRY 387

Query: 1277 CPSIVNAKQLGLPSS 1321
             P IV     GLP++
Sbjct: 388  PPGIVGVAPGGLPAA 402



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>O94574:YGDH_SCHPO Putative 2-hydroxyacid dehydrogenase C1773.17c - Schizosaccharomyces|
            pombe (Fission yeast)
          Length = 340

 Score =  104 bits (260), Expect = 9e-22
 Identities = 73/239 (30%), Positives = 114/239 (47%)
 Frame = +2

Query: 437  FSNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGL 616
            F   A GYNNVDVD A +NG+ + NTP   TE T            R   EA+Q +R G 
Sbjct: 87   FVTGAAGYNNVDVDWATRNGVYVANTPNGPTEGTANMNLMLFMCTLRGAREAEQSLRLGK 146

Query: 617  YDGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTA 796
               W  +L + +   G+ VG+IG G IG ++A+ ++      ++Y   +   RLE     
Sbjct: 147  ---WRQNLSLTDDPYGKRVGIIGMGAIGKSFAQKILP-LGCEIVY---HNRNRLEA---- 195

Query: 797  YGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLV 976
                     E+        S +E+L  +DVIS++  L   T+ LI+ +    MK    ++
Sbjct: 196  --------EEEKRLGASFVSFDELLSSSDVISINCPLTPATHDLISTKEFEKMKDGVYII 247

Query: 977  NASRGPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWT 1153
            N +RG +I+E A ++ +K+  + R GLDVF +EP       E     + PH    + +T
Sbjct: 248  NTARGAIINEDAFIKAIKSGKVARAGLDVFLNEPTPNKFWLECDKVTIQPHCGVYTNFT 306



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>O14075:YEAA_SCHPO Putative 2-hydroxyacid dehydrogenase UNK4.10 - Schizosaccharomyces|
            pombe (Fission yeast)
          Length = 334

 Score =  104 bits (260), Expect = 9e-22
 Identities = 71/253 (28%), Positives = 120/253 (47%), Gaps = 4/253 (1%)
 Frame = +2

Query: 443  NMAVGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYD 622
            ++  GY  VDV A    GI + + P  + + T            R   +       G+++
Sbjct: 86   HLGAGYETVDVAACTARGIQVSHVPKAVDDATADVGIFLMLGALRGFNQ-------GIFE 138

Query: 623  ----GWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFV 790
                 W  +    +  +G+T+G++G G IG   A+     F M ++Y   +  T L +  
Sbjct: 139  LHKNNWNANCKPSHDPEGKTLGILGLGGIGKTMAKRA-RAFDMKIVY---HNRTPLPEEE 194

Query: 791  TAYGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAV 970
                +F+              S +++L ++DV+SL+  L+  T H+I       MK+  V
Sbjct: 195  AEGAEFV--------------SFDDLLAKSDVLSLNLPLNAHTRHIIGKPEFQKMKRGIV 240

Query: 971  LVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKW 1150
            +VN +RG V+DE ALVE L    ++  GLDVFE+EP + PGL E +  +++PH+ + S  
Sbjct: 241  IVNTARGAVMDEAALVEALDEGIVYSAGLDVFEEEPKIHPGLLENEKVILLPHLGTNSLE 300

Query: 1151 TREGMATLAALNV 1189
            T+  M     +NV
Sbjct: 301  TQYKMECAVLMNV 313



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>P0A544:SERA_MYCTU D-3-phosphoglycerate dehydrogenase - Mycobacterium tuberculosis|
          Length = 528

 Score =  104 bits (260), Expect = 9e-22
 Identities = 92/314 (29%), Positives = 137/314 (43%)
 Frame = +2

Query: 326  DDILALIGDHCHGVIGQLTEDWGEVLFSALKRAGGTAFSNMAVGYNNVDVDAANKNGIAI 505
            D +LA + +    ++   T    EVL +A K       +   VG +NVDVDAA   G+ +
Sbjct: 35   DKLLAAVPEADALLVRSATTVDAEVLAAAPKLK---IVARAGVGLDNVDVDAATARGVLV 91

Query: 506  GNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLPHLFVGNLLKGQTVGVIG 685
             N P     +             R+I  AD  +R      W    F G  + G+TVGV+G
Sbjct: 92   VNAPTSNIHSAAEHALALLLAASRQIPAADASLREHT---WKRSSFSGTEIFGKTVGVVG 148

Query: 686  AGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEE 865
             GRIG   A+  I  F   ++ +D Y S               A   Q        S+++
Sbjct: 149  LGRIGQLVAQR-IAAFGAYVVAYDPYVSP--------------ARAAQ--LGIELLSLDD 191

Query: 866  VLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMF 1045
            +L  AD IS+H      T  LI+ E LA  K   ++VNA+RG ++DE AL + +    + 
Sbjct: 192  LLARADFISVHLPKTPETAGLIDKEALAKTKPGVIIVNAARGGLVDEAALADAITGGHVR 251

Query: 1046 RVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKGYPVWGN 1225
              GLDVF  EP     L E+   VV PH+ +++   ++   T  A +V   + G  V   
Sbjct: 252  AAGLDVFATEPCTDSPLFELAQVVVTPHLGASTAEAQDRAGTDVAESVRLALAGEFVPDA 311

Query: 1226 PNAVEPFLDEEATP 1267
             N     ++EE  P
Sbjct: 312  VNVGGGVVNEEVAP 325



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>P0A545:SERA_MYCBO D-3-phosphoglycerate dehydrogenase - Mycobacterium bovis|
          Length = 528

 Score =  104 bits (260), Expect = 9e-22
 Identities = 92/314 (29%), Positives = 137/314 (43%)
 Frame = +2

Query: 326  DDILALIGDHCHGVIGQLTEDWGEVLFSALKRAGGTAFSNMAVGYNNVDVDAANKNGIAI 505
            D +LA + +    ++   T    EVL +A K       +   VG +NVDVDAA   G+ +
Sbjct: 35   DKLLAAVPEADALLVRSATTVDAEVLAAAPKLK---IVARAGVGLDNVDVDAATARGVLV 91

Query: 506  GNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLPHLFVGNLLKGQTVGVIG 685
             N P     +             R+I  AD  +R      W    F G  + G+TVGV+G
Sbjct: 92   VNAPTSNIHSAAEHALALLLAASRQIPAADASLREHT---WKRSSFSGTEIFGKTVGVVG 148

Query: 686  AGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEE 865
             GRIG   A+  I  F   ++ +D Y S               A   Q        S+++
Sbjct: 149  LGRIGQLVAQR-IAAFGAYVVAYDPYVSP--------------ARAAQ--LGIELLSLDD 191

Query: 866  VLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMF 1045
            +L  AD IS+H      T  LI+ E LA  K   ++VNA+RG ++DE AL + +    + 
Sbjct: 192  LLARADFISVHLPKTPETAGLIDKEALAKTKPGVIIVNAARGGLVDEAALADAITGGHVR 251

Query: 1046 RVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKGYPVWGN 1225
              GLDVF  EP     L E+   VV PH+ +++   ++   T  A +V   + G  V   
Sbjct: 252  AAGLDVFATEPCTDSPLFELAQVVVTPHLGASTAEAQDRAGTDVAESVRLALAGEFVPDA 311

Query: 1226 PNAVEPFLDEEATP 1267
             N     ++EE  P
Sbjct: 312  VNVGGGVVNEEVAP 325



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>P56546:CTBP2_MOUSE C-terminal-binding protein 2 - Mus musculus (Mouse)|
          Length = 445

 Score =  104 bits (260), Expect = 9e-22
 Identities = 78/259 (30%), Positives = 125/259 (48%), Gaps = 10/259 (3%)
 Frame = +2

Query: 455  GYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLP 634
            GY+NVD+ AA + GIA+ N P    E T            RR     Q +R G     + 
Sbjct: 107  GYDNVDIKAAGELGIAVCNIPSAAVEETADSTVCHILNLYRRNTWLYQALREGTRVQSVE 166

Query: 635  HLFV----GNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYG 802
             +         ++G+T+G+IG GR G A A +  + F  ++I++D Y    +E+ +    
Sbjct: 167  QIREVASGAARIRGETLGLIGFGRTGQAVA-VRAKAFGFSVIFYDPYLQDGIERSLGV-- 223

Query: 803  QFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNA 982
                         +R  +++++L ++D +SLH  L++  +HLIN   +  M++ A LVNA
Sbjct: 224  -------------QRVYTLQDLLYQSDCVSLHCNLNEHNHHLINDFTIKQMRQGAFLVNA 270

Query: 983  SRGPVIDEVALVEHLKANPMFRVGLDVFEDEP--YMKPGLAEMKNAVVVPHIA----SAS 1144
            +RG ++DE AL + LK   +    LDV E EP  + +  L +  N +  PH A     AS
Sbjct: 271  ARGGLVDEKALAQALKEGRIRGAALDVHESEPFSFAQGPLKDAPNLICTPHTAWYSEQAS 330

Query: 1145 KWTREGMATLAALNVLGKI 1201
               RE  AT     + G+I
Sbjct: 331  LEMREAAATEIRRAITGRI 349



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>Q0VCQ1:CTBP2_BOVIN C-terminal-binding protein 2 - Bos taurus (Bovine)|
          Length = 445

 Score =  104 bits (259), Expect = 1e-21
 Identities = 78/259 (30%), Positives = 126/259 (48%), Gaps = 10/259 (3%)
 Frame = +2

Query: 455  GYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLP 634
            GY+NVD+ AA + GIA+ N P    E T            RR     Q +R G     + 
Sbjct: 107  GYDNVDIKAAGELGIAVCNIPSAAVEETADSTICHILNLYRRNTWLYQALREGTRVQSVE 166

Query: 635  HLFV----GNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYG 802
             +         ++G+T+G+IG GR G A A +  + F  +++++D Y             
Sbjct: 167  QIREVASGAARIRGETLGLIGFGRTGQAVA-VRAKAFGFSVLFYDPY------------- 212

Query: 803  QFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNA 982
              L+   E+ +  +R  +++++L ++D +SLH  L++  +HLIN   +  M++ A LVNA
Sbjct: 213  --LQDGTERSLGVQRVYTLQDLLYQSDCVSLHCNLNEHNHHLINDFTIKQMRQGAFLVNA 270

Query: 983  SRGPVIDEVALVEHLKANPMFRVGLDVFEDEP--YMKPGLAEMKNAVVVPHIA----SAS 1144
            +RG ++DE AL + LK   +    LDV E EP  + +  L +  N +  PH A     AS
Sbjct: 271  ARGGLVDEKALAQALKEGRIRGAALDVHESEPFSFAQGPLKDAPNLICTPHTAWYSEQAS 330

Query: 1145 KWTREGMATLAALNVLGKI 1201
               RE  AT     + G+I
Sbjct: 331  LEMREAAATEIRRAITGRI 349



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>Q9Z2F5:CTBP1_RAT C-terminal-binding protein 1 - Rattus norvegicus (Rat)|
          Length = 430

 Score =  104 bits (259), Expect = 1e-21
 Identities = 76/257 (29%), Positives = 124/257 (48%), Gaps = 6/257 (2%)
 Frame = +2

Query: 455  GYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLP 634
            G++N+D+ +A   GIA+ N P    E T            RR     Q +R G     + 
Sbjct: 90   GFDNIDIKSAGDLGIAVCNVPAASVEETADSTLCHILNLYRRTTWLHQALREGTRVQSVE 149

Query: 635  HLFV----GNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYG 802
             +         ++G+T+G+IG GR+G A A +  + F  N++++D Y S  +E+      
Sbjct: 150  QIREVASGAARIRGETLGIIGLGRVGQAVA-LRAKAFGFNVLFYDPYLSDGIER------ 202

Query: 803  QFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNA 982
                A G Q     R S+++++L  +D ++LH  L++  +HLIN   +  M++ A LVN 
Sbjct: 203  ----ALGLQ-----RVSTLQDLLFHSDCVTLHCGLNEHNHHLINDFTVKQMRQGAFLVNT 253

Query: 983  SRGPVIDEVALVEHLKANPMFRVGLDVFEDEP--YMKPGLAEMKNAVVVPHIASASKWTR 1156
            +RG ++DE AL + LK   +    LDV E EP  + +  L +  N +  PH A  S+   
Sbjct: 254  ARGGLVDEKALAQALKEGRIRGAALDVHESEPFSFSQGPLKDAPNLICTPHAAWYSEQAS 313

Query: 1157 EGMATLAALNVLGKIKG 1207
              M   AA  +   I G
Sbjct: 314  IEMREEAAREIRRAITG 330



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>O88712:CTBP1_MOUSE C-terminal-binding protein 1 - Mus musculus (Mouse)|
          Length = 441

 Score =  104 bits (259), Expect = 1e-21
 Identities = 76/257 (29%), Positives = 124/257 (48%), Gaps = 6/257 (2%)
 Frame = +2

Query: 455  GYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLP 634
            G++N+D+ +A   GIA+ N P    E T            RR     Q +R G     + 
Sbjct: 101  GFDNIDIKSAGDLGIAVCNVPAASVEETADSTLCHILNLYRRTTWLHQALREGTRVQSVE 160

Query: 635  HLFV----GNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYG 802
             +         ++G+T+G+IG GR+G A A +  + F  N++++D Y S  +E+      
Sbjct: 161  QIREVASGAARIRGETLGIIGLGRVGQAVA-LRAKAFGFNVLFYDPYLSDGIER------ 213

Query: 803  QFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNA 982
                A G Q     R S+++++L  +D ++LH  L++  +HLIN   +  M++ A LVN 
Sbjct: 214  ----ALGLQ-----RVSTLQDLLFHSDCVTLHCGLNEHNHHLINDFTVKQMRQGAFLVNT 264

Query: 983  SRGPVIDEVALVEHLKANPMFRVGLDVFEDEP--YMKPGLAEMKNAVVVPHIASASKWTR 1156
            +RG ++DE AL + LK   +    LDV E EP  + +  L +  N +  PH A  S+   
Sbjct: 265  ARGGLVDEKALAQALKEGRIRGAALDVHESEPFSFSQGPLKDAPNLICTPHAAWYSEQAS 324

Query: 1157 EGMATLAALNVLGKIKG 1207
              M   AA  +   I G
Sbjct: 325  IEMREEAAREIRRAITG 341



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>Q13363:CTBP1_HUMAN C-terminal-binding protein 1 - Homo sapiens (Human)|
          Length = 440

 Score =  103 bits (258), Expect = 2e-21
 Identities = 76/257 (29%), Positives = 124/257 (48%), Gaps = 6/257 (2%)
 Frame = +2

Query: 455  GYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLP 634
            G++N+D+ +A   GIA+ N P    E T            RR     Q +R G     + 
Sbjct: 101  GFDNIDIKSAGDLGIAVCNVPAASVEETADSTLCHILNLYRRATWLHQALREGTRVQSVE 160

Query: 635  HLFV----GNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYG 802
             +         ++G+T+G+IG GR+G A A +  + F  N++++D Y S  +E+      
Sbjct: 161  QIREVASGAARIRGETLGIIGLGRVGQAVA-LRAKAFGFNVLFYDPYLSDGVER------ 213

Query: 803  QFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNA 982
                A G Q     R S+++++L  +D ++LH  L++  +HLIN   +  M++ A LVN 
Sbjct: 214  ----ALGLQ-----RVSTLQDLLFHSDCVTLHCGLNEHNHHLINDFTVKQMRQGAFLVNT 264

Query: 983  SRGPVIDEVALVEHLKANPMFRVGLDVFEDEP--YMKPGLAEMKNAVVVPHIASASKWTR 1156
            +RG ++DE AL + LK   +    LDV E EP  + +  L +  N +  PH A  S+   
Sbjct: 265  ARGGLVDEKALAQALKEGRIRGAALDVHESEPFSFSQGPLKDAPNLICTPHAAWYSEQAS 324

Query: 1157 EGMATLAALNVLGKIKG 1207
              M   AA  +   I G
Sbjct: 325  IEMREEAAREIRRAITG 341



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>P52643:LDHD_ECOLI D-lactate dehydrogenase - Escherichia coli|
          Length = 329

 Score =  103 bits (257), Expect = 2e-21
 Identities = 76/240 (31%), Positives = 108/240 (45%)
 Frame = +2

Query: 356  CHGVIGQLTEDWGEVLFSALKRAGGTAFSNMAVGYNNVDVDAANKNGIAIGNTPGVLTET 535
            C  V   + +D    +   LK+ G    +    G+NNVD+DAA + G+ +   P    E 
Sbjct: 45   CEAVCIFVNDDGSRPVLEELKKHGVKYIALRCAGFNNVDLDAAKELGLKVVRVPAYDPEA 104

Query: 536  TXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAYAR 715
                         RRI  A Q  R   +   L  L  G  + G+T GVIG G+IG A  R
Sbjct: 105  VAEHAIGMMMTLNRRIHRAYQRTRDANFS--LEGL-TGFTMYGKTAGVIGTGKIGVAMLR 161

Query: 716  MMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADVISL 895
            ++ +GF M L+ FD Y S    +    Y                   +  +  E+DVISL
Sbjct: 162  IL-KGFGMRLLAFDPYPSAAALELGVEY-----------------VDLPTLFSESDVISL 203

Query: 896  HPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDE 1075
            H  L    YHL+N      MK   ++VN SRG +ID  A +E LK   +  +G+DV+E+E
Sbjct: 204  HCPLTPENYHLLNEAAFEQMKNGVMIVNTSRGALIDSQAAIEALKNQKIGSLGMDVYENE 263



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>Q9YHU0:CTBP1_XENLA C-terminal-binding protein 1 - Xenopus laevis (African clawed frog)|
          Length = 440

 Score =  103 bits (256), Expect = 3e-21
 Identities = 76/257 (29%), Positives = 123/257 (47%), Gaps = 6/257 (2%)
 Frame = +2

Query: 455  GYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLP 634
            G++N+D+ +A   GIA+ N P    E T            RR     Q +R G     + 
Sbjct: 101  GFDNIDIKSAGDLGIAVCNVPAASVEETADSTMCHILNLYRRTTWLHQALREGTRVQSVE 160

Query: 635  HLFV----GNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYG 802
             +         ++G+T+G+IG GR+G A A +  + F  N+ ++D Y S  +E+      
Sbjct: 161  QIREVASGAARIRGETLGIIGLGRVGQAVA-LRAKTFGFNVFFYDPYLSDGIER------ 213

Query: 803  QFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNA 982
                A G Q     R S+++++L  +D ++LH  L++  +HLIN   +  M++ A LVN 
Sbjct: 214  ----ALGLQ-----RVSTLQDLLFHSDCVTLHCGLNEHNHHLINDFTIKQMRQGAFLVNT 264

Query: 983  SRGPVIDEVALVEHLKANPMFRVGLDVFEDEP--YMKPGLAEMKNAVVVPHIASASKWTR 1156
            +RG ++DE AL + LK   +    LDV E EP  + +  L +  N +  PH A  S+   
Sbjct: 265  ARGGLVDEKALAQALKEGRIRGAALDVHESEPFSFTQGPLKDAPNLICTPHAAWYSEQAS 324

Query: 1157 EGMATLAALNVLGKIKG 1207
              M   AA  +   I G
Sbjct: 325  IEMREEAAREIRRAITG 341



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>Q5EAD2:SERA_BOVIN D-3-phosphoglycerate dehydrogenase - Bos taurus (Bovine)|
          Length = 533

 Score =  102 bits (255), Expect = 3e-21
 Identities = 84/311 (27%), Positives = 142/311 (45%), Gaps = 1/311 (0%)
 Frame = +2

Query: 305  KKTILSVDDILALIGDHCHG-VIGQLTEDWGEVLFSALKRAGGTAFSNMAVGYNNVDVDA 481
            +K  LS ++++A + D C G ++   T+   +++ +A K            G +NVD++A
Sbjct: 32   EKQNLSKEELIAELQD-CEGLIVRSATKVTSDIINAAEKLQ---VVGRAGTGVDNVDLEA 87

Query: 482  ANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLPHLFVGNLLK 661
            A + GI + NTP   + +             R+I +A   M+ G    W    F+G  L 
Sbjct: 88   ATRKGILVMNTPNGNSLSAAELTCGMIMCLARQIPQAAASMKDGK---WERKKFMGTELN 144

Query: 662  GQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTW 841
            G+ +G++G GRIG   A  M + F M  I +D   S  +            + G Q +  
Sbjct: 145  GKVLGILGLGRIGREVATRM-QSFGMKTIGYDPIISPEVSA----------SFGVQQLP- 192

Query: 842  KRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVE 1021
                 +E++    D I++H  L  +T  L+N    A  KK   +VN +RG ++DE AL+ 
Sbjct: 193  -----LEQIWPLCDFITVHTPLLPSTTGLLNDSTFAQCKKGVCVVNCARGGIVDEGALLR 247

Query: 1022 HLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKI 1201
             L++       LDVF +EP     L   +N +  PH+ +++K  +       AL  +  +
Sbjct: 248  ALQSGQCAGAALDVFTEEPPRDRALVNHENVISCPHLGASTKEAQSRCGEEIALQFVDMV 307

Query: 1202 KGYPVWGNPNA 1234
            KG  + G  NA
Sbjct: 308  KGKALAGVVNA 318



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>Q5R7M2:SERA_PONPY D-3-phosphoglycerate dehydrogenase - Pongo pygmaeus (Orangutan)|
          Length = 533

 Score =  102 bits (254), Expect = 5e-21
 Identities = 85/311 (27%), Positives = 143/311 (45%), Gaps = 1/311 (0%)
 Frame = +2

Query: 305  KKTILSVDDILALIGDHCHG-VIGQLTEDWGEVLFSALKRAGGTAFSNMAVGYNNVDVDA 481
            +K  LS ++++A + D C G ++   T+   +V+ +A K            G +NVD++A
Sbjct: 32   EKQNLSKEELIAELQD-CEGLIVRSATKVTADVINAAEKLQ---VVGRAGTGVDNVDLEA 87

Query: 482  ANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLPHLFVGNLLK 661
            A + GI + NTP   + +             R+I +A   M+ G    W    F+G  L 
Sbjct: 88   ATRKGILVMNTPNGNSLSAAELTCGMIMCLARQIPQATASMKDGK---WERKKFMGTELN 144

Query: 662  GQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTW 841
            G+T+G++G GRIG   A  M +   M  I +D   S  +            + G Q +  
Sbjct: 145  GKTLGILGLGRIGREVAIRM-QSLGMKTIGYDPIISPEVSA----------SFGVQQLP- 192

Query: 842  KRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVE 1021
                 +EE+    D I++H  L  +T  L+N    A  KK   +VN +RG ++DE AL+ 
Sbjct: 193  -----LEEIWPLCDFITVHTPLLPSTTGLLNDNTFAQCKKGVRVVNCARGGIVDEGALLR 247

Query: 1022 HLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKI 1201
             L++       LDVF +EP     L + +N +  PH+ +++K  +       A+  +  +
Sbjct: 248  ALQSGQCAGAALDVFTEEPPRGRALVDHENVISCPHLGASTKEAQSRCGEEIAVQFVDMV 307

Query: 1202 KGYPVWGNPNA 1234
            KG  + G  NA
Sbjct: 308  KGKSLTGVVNA 318



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>P26297:LDHD_LACDA D-lactate dehydrogenase - Lactobacillus delbrueckii subsp. bulgaricus|
            (strain ATCC 11842 / DSM 20081)
          Length = 333

 Score =  102 bits (254), Expect = 5e-21
 Identities = 86/299 (28%), Positives = 137/299 (45%), Gaps = 17/299 (5%)
 Frame = +2

Query: 362  GVIGQLTEDWGEVLFSALKRAGGTAFSNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTX 541
            GV+     D+      AL   G T  S   VG +N+D+  A + G  I N P      + 
Sbjct: 49   GVVVYQQLDYTAETLQALADNGITKMSLRNVGVDNIDMAKAKELGFQITNVPVY----SP 104

Query: 542  XXXXXXXXXXXRRIVEADQFM--RAGLYD-GWLPHLFVGNLLKGQTVGVIGAGRIGSAYA 712
                        RI+  D+ M  +   +D  W P   +G  ++ Q VGVIG G IG  + 
Sbjct: 105  NAIAEHAAIQAARILRQDKAMDEKVARHDLRWAPT--IGREVRDQVVGVIGTGHIGQVFM 162

Query: 713  RMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADVIS 892
            ++M EGF   +I +D++++  LEK     G ++              S++++ ++ADVIS
Sbjct: 163  QIM-EGFGAKVIAYDIFRNPELEK----KGYYV-------------DSLDDLYKQADVIS 204

Query: 893  LHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFED 1072
            LH        H+IN E +A MK++ V+VN SRGP++D  A++  L +  +F   +DV+E 
Sbjct: 205  LHVPDVPANVHMINDESIAKMKQDVVIVNVSRGPLVDTDAVIRGLDSGKIFGYAMDVYEG 264

Query: 1073 E-----------PYMKPGLAEM---KNAVVVPHIASASKWTREGMATLAALNVLGKIKG 1207
            E            +    LA++    N +V PH A  +      M   A  N L  ++G
Sbjct: 265  EVGIFNEDWEGKEFPDARLADLIARPNVLVTPHTAFYTTHAVRNMVVKAFDNNLELVEG 323



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>P44501:DDH_HAEIN 2-hydroxyacid dehydrogenase homolog - Haemophilus influenzae|
          Length = 331

 Score =  102 bits (253), Expect = 6e-21
 Identities = 73/244 (29%), Positives = 120/244 (49%)
 Frame = +2

Query: 344  IGDHCHGVIGQLTEDWGEVLFSALKRAGGTAFSNMAVGYNNVDVDAANKNGIAIGNTPGV 523
            + +HC  V   + ++    +   L   G    +    G+NNVD+ AA + GI +   P  
Sbjct: 41   LAEHCEVVCIFVNDNGSRKVLEKLAALGVKIVALRCAGFNNVDLKAAQELGIQVVRVPAY 100

Query: 524  LTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLPHLFVGNLLKGQTVGVIGAGRIGS 703
              E              RRI  A Q  R   +   L  L +G  + G+TVGVIG G+IG 
Sbjct: 101  SPEAVAEHTIGLMMTLNRRIHRAYQRTREANFS--LEGL-IGFNMYGRTVGVIGTGKIGI 157

Query: 704  AYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREAD 883
            A  R++ +GF MN++ +D +++  +E+     GQ+++              ++E+  ++ 
Sbjct: 158  AVMRIL-KGFGMNILAYDPFKNPVVEELG---GQYVE--------------LDELYAKSH 199

Query: 884  VISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDV 1063
            VI+LH       YHL+N E  A MK   ++VN SRG +ID  A ++ LK   +  +G+DV
Sbjct: 200  VITLHCPATPENYHLLNCEAFAKMKDGVMIVNTSRGSLIDTQAAIDALKQRKIGALGMDV 259

Query: 1064 FEDE 1075
            +E+E
Sbjct: 260  YENE 263



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>P30901:LDHD_LACHE D-lactate dehydrogenase - Lactobacillus helveticus|
          Length = 337

 Score =  101 bits (252), Expect = 8e-21
 Identities = 86/296 (29%), Positives = 131/296 (44%), Gaps = 14/296 (4%)
 Frame = +2

Query: 362  GVIGQLTEDWGEVLFSALKRAGGTAFSNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTX 541
            GV+     D+      AL  AG T  S   VG +N+D+D A + G  I N P        
Sbjct: 49   GVVVYQQLDYTADTLQALADAGVTKMSLRNVGVDNIDMDKAKELGFQITNVPVYSPNAIA 108

Query: 542  XXXXXXXXXXXRRIVEADQFMRAGLYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMM 721
                       R+    D+ M A     W P   +G  ++ Q VGV+G G IG  + R+M
Sbjct: 109  EHAAIQAARVLRQDKRMDEKM-AKRDLRWAPT--IGREVRDQVVGVVGTGHIGQVFMRIM 165

Query: 722  IEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLHP 901
             EGF   +I +D++++  LEK     G ++              S++++ ++ADVISLH 
Sbjct: 166  -EGFGAKVIAYDIFKNPELEK----KGYYV-------------DSLDDLYKQADVISLHV 207

Query: 902  VLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDE-- 1075
                   H+IN + +A MK   V+VN SRG ++D  A++  L +  +F   +D +EDE  
Sbjct: 208  PDVPANVHMINDKSIAEMKDGVVIVNCSRGRLVDTDAVIRGLDSGKIFGFVMDTYEDEVG 267

Query: 1076 ---------PYMKPGLAEM---KNAVVVPHIASASKWTREGMATLAALNVLGKIKG 1207
                      +    LA++    N +V PH A  +      M   A  N L  I G
Sbjct: 268  VFNKDWEGKEFPDKRLADLIDRPNVLVTPHTAFYTTHAVRNMVVKAFNNNLKLING 323



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>P30799:DDH_ZYMMO 2-hydroxyacid dehydrogenase homolog - Zymomonas mobilis|
          Length = 331

 Score =  100 bits (248), Expect = 2e-20
 Identities = 70/213 (32%), Positives = 100/213 (46%), Gaps = 6/213 (2%)
 Frame = +2

Query: 455  GYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRI------VEADQFMRAGL 616
            GYNNVD+DAA K  I +   P     +             R+I      V  + F   GL
Sbjct: 78   GYNNVDLDAAKKLNIKVVRVPAYSPYSVAEYAVGMLLTLNRQISRGLKRVRENNFSLEGL 137

Query: 617  YDGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTA 796
                     +G  +  +TVG+IG G IGS +A +M  GF  N+I +  +    L K V  
Sbjct: 138  ---------IGLDVHDKTVGIIGVGHIGSVFAHIMTHGFGANVIAYKPHPDPELAKKVGF 188

Query: 797  YGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLV 976
                            R +S++EV+  +D+ISLH  L    +H+IN E LA  KK   LV
Sbjct: 189  ----------------RFTSLDEVIETSDIISLHCPLTPENHHMINEETLARAKKGFYLV 232

Query: 977  NASRGPVIDEVALVEHLKANPMFRVGLDVFEDE 1075
            N SRG ++D  A+++ LKA  +     DV+E+E
Sbjct: 233  NTSRGGLVDTKAVIKSLKAKHLGGYAADVYEEE 265



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>O46036:CTBP_DROME C-terminal-binding protein - Drosophila melanogaster (Fruit fly)|
          Length = 476

 Score =  100 bits (248), Expect = 2e-20
 Identities = 83/297 (27%), Positives = 132/297 (44%), Gaps = 16/297 (5%)
 Frame = +2

Query: 455  GYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLP 634
            G +N+DV AA + GIA+ N PG   E              RR       +R G       
Sbjct: 101  GTDNIDVKAAGELGIAVCNVPGYGVEEVADTTMCLILNLYRRTYWLANMVREG------- 153

Query: 635  HLFVGN-----------LLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLE 781
              F G             ++G T+G++G GRIGSA A +  + F  N+I++D Y    ++
Sbjct: 154  KKFTGPEQVREAAHGCARIRGDTLGLVGLGRIGSAVA-LRAKAFGFNVIFYDPYLPDGID 212

Query: 782  KFVTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKK 961
            K +                  R  +++++L ++D +SLH  L++  +HLIN   +  M+ 
Sbjct: 213  KSLGL---------------TRVYTLQDLLFQSDCVSLHCTLNEHNHHLINEFTIKQMRP 257

Query: 962  EAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEPY--MKPGLAEMKNAVVVPHIA 1135
             A LVN +RG ++D+  L   LK   +    LDV E+EPY   +  L +  N +  PH A
Sbjct: 258  GAFLVNTARGGLVDDETLALALKQGRIRAAALDVHENEPYNVFQGALKDAPNLICTPHAA 317

Query: 1136 SASKWTREGMATLAALNVLGKIKGYPVWGNPNAVEPFLDEE---ATPPPACPSIVNA 1297
              S  +   +  +AA  +   I G      P+ +   +++E    TPP A    V A
Sbjct: 318  FFSDASATELREMAATEIRRAIVG----NIPDVLRNCVNKEYFMRTPPAAAAGGVAA 370



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>P73821:SERA_SYNY3 D-3-phosphoglycerate dehydrogenase - Synechocystis sp. (strain PCC|
            6803)
          Length = 554

 Score = 99.0 bits (245), Expect = 5e-20
 Identities = 72/254 (28%), Positives = 117/254 (46%)
 Frame = +2

Query: 452  VGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWL 631
            VG +N+DV AA + GI + N+P   T               R I +A++ ++      W 
Sbjct: 100  VGVDNIDVPAATRQGIVVVNSPEGNTIAAAEHALAMMMALARHIPDANKSVKESK---WE 156

Query: 632  PHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFL 811
               F+G  +  +T+GV+G G+IGS  A +  +   M L+ +D + S      +       
Sbjct: 157  RKQFIGTEVYKKTLGVVGLGKIGSHVAGVA-KAMGMKLLAYDPFISQERADQIGC----- 210

Query: 812  KANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRG 991
                           ++ +  EAD I+LH      T +LIN E LA MK  A ++N SRG
Sbjct: 211  -----------TLVDLDLLFSEADFITLHIPKTPETANLINAETLAKMKPTARIINCSRG 259

Query: 992  PVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMAT 1171
             +IDE ALV  ++   +    LDVF  EP  +  L E  N ++ PH+ ++++  +  +A 
Sbjct: 260  GIIDEEALVTAIETAQIGGAALDVFAQEPLGESRLREFSNVILTPHLGASTEEAQVNVAV 319

Query: 1172 LAALNVLGKIKGYP 1213
              A  +   + G P
Sbjct: 320  DVAEQIRDVLLGLP 333



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>Q59642:LDHD_PEDAC D-lactate dehydrogenase - Pediococcus acidilactici|
          Length = 331

 Score = 97.4 bits (241), Expect = 1e-19
 Identities = 81/289 (28%), Positives = 129/289 (44%), Gaps = 14/289 (4%)
 Frame = +2

Query: 362  GVIGQLTEDWGEVLFSALKRAGGTAFSNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTX 541
            GV+    + +   LF  +   G  AFS   VG +NV  DA  KN I I N P        
Sbjct: 47   GVVAYQQKPYTADLFDKMHEFGIHAFSLRNVGLDNVPADALKKNDIKISNVPAYSPRAIA 106

Query: 542  XXXXXXXXXXXRRIVEADQFMRAGLYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMM 721
                       R+I E +  M  G Y  W P   +G  L   TVGVIG GRIG A A  +
Sbjct: 107  ELSVTQLLALLRKIPEFEYKMAHGDYR-WEPD--IGLELNQMTVGVIGTGRIGRA-AIDI 162

Query: 722  IEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLHP 901
             + F   +I +D++++  LEK     G ++              ++EE+ ++A+VI+LH 
Sbjct: 163  FKPFGAKVIAYDVFRNPALEK----EGMYV-------------DTLEELYQQANVITLHV 205

Query: 902  VLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFE---- 1069
               K  YH+++ +    M+    ++N +RG ++D  AL++ L +  +    LD +E    
Sbjct: 206  PALKDNYHMLDEKAFGQMQDGTFILNFARGTLVDTPALLKALDSGKVAGAALDTYENEVG 265

Query: 1070 -------DEPYMKP---GLAEMKNAVVVPHIASASKWTREGMATLAALN 1186
                   D+P   P    L   +N ++ PH A  ++   + M  +A  N
Sbjct: 266  IFDVDHGDQPIDDPVFNDLMSRRNVMITPHAAFYTRPAVKNMVQIALDN 314



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>P43885:SERA_HAEIN D-3-phosphoglycerate dehydrogenase - Haemophilus influenzae|
          Length = 410

 Score = 97.1 bits (240), Expect = 2e-19
 Identities = 72/259 (27%), Positives = 121/259 (46%), Gaps = 6/259 (2%)
 Frame = +2

Query: 452  VGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWL 631
            +G N VD++AA   GI + N P   T +             R + +A+  +  G+   W 
Sbjct: 85   IGTNQVDLNAAKARGIPVFNAPFSNTRSVAELVLGEILLLMRNVPQANAEVHRGV---WN 141

Query: 632  PHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFL 811
                  + ++G+ +G+IG G IGS  + ++ E   M++ ++D+     L           
Sbjct: 142  KSATGSHEVRGKKLGIIGYGHIGSQLS-IIAESLGMDVYFYDIENKLPLGNA-------- 192

Query: 812  KANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRG 991
                      K+  S+EE+L   DV+SLH     +T +L+N  R+A +K+ A+L+NA+RG
Sbjct: 193  ----------KQVRSLEELLSSCDVVSLHVPELPSTKNLMNVARIAQLKQGAILINAARG 242

Query: 992  PVIDEVALVEHLKANPMFRVGLDVFEDEP------YMKPGLAEMKNAVVVPHIASASKWT 1153
             V+D  AL + LK   +    +DVF  EP      ++ P L E  N ++ PHI  ++   
Sbjct: 243  TVVDIDALAQALKDGKLQGAAIDVFPVEPASINEEFISP-LREFDNVILTPHIGGSTAEA 301

Query: 1154 REGMATLAALNVLGKIKGY 1210
            +E +       V GK   Y
Sbjct: 302  QENI----GFEVAGKFVKY 316



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>P45250:Y1556_HAEIN Putative 2-hydroxyacid dehydrogenase HI1556 - Haemophilus influenzae|
          Length = 315

 Score = 94.0 bits (232), Expect = 2e-18
 Identities = 74/243 (30%), Positives = 109/243 (44%), Gaps = 11/243 (4%)
 Frame = +2

Query: 449  AVGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGW 628
            A G NNVD+ AA + GIA+ N  G  + T               +     ++R      W
Sbjct: 72   ATGTNNVDLVAAEEMGIAVRNVTGYSSTTVPEHVIGLIFSLKHSLAG---WLRDQTEAKW 128

Query: 629  LPHL------FVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFV 790
                      +    ++G T+GV G G +G+   R+      M ++Y +   +T   +  
Sbjct: 129  AESKQFCYFDYPITDVRGSTLGVFGKGCLGTEVGRLA-NAVGMKVLYAEHKDATVCREGY 187

Query: 791  TAYGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAV 970
            T +                    +EVL++AD+++LH  L +TT  LIN E L+ MKK A 
Sbjct: 188  TPF--------------------DEVLKQADIVTLHCPLTETTKDLINAETLSKMKKGAF 227

Query: 971  LVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKP-----GLAEMKNAVVVPHIA 1135
            L+N  RGP+IDE+ALV+ LK   +    LDV   EP  K          M N ++ PHIA
Sbjct: 228  LINTGRGPLIDELALVDALKTGHLGGAALDVMVKEPPEKDNPLILAAKTMPNLIITPHIA 287

Query: 1136 SAS 1144
             AS
Sbjct: 288  WAS 290



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>Q6GDS2:LDHD_STAAR D-lactate dehydrogenase - Staphylococcus aureus (strain MRSA252)|
          Length = 330

 Score = 91.7 bits (226), Expect = 8e-18
 Identities = 74/269 (27%), Positives = 123/269 (45%), Gaps = 14/269 (5%)
 Frame = +2

Query: 371  GQLTEDWGEVLFSALKRAGGTAFSNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTXXXX 550
            G+L  D    ++  L+  G    +    G++  D+D A K+ I I N P    ET     
Sbjct: 55   GKLEND----VYPKLESYGIKQIAQRTAGFDMYDLDLAKKHNIVISNVPSYSPETIAEYS 110

Query: 551  XXXXXXXXRRIVEADQFMRAGLYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEG 730
                    RR  + ++ ++A  +  W   + +   +K  TV +IG GRIG+A A++   G
Sbjct: 111  VSIALQLVRRFPDIERRVQAHDFT-WQAEI-MSKPVKNMTVAIIGTGRIGAATAKIYA-G 167

Query: 731  FKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLD 910
            F   +  +D Y +  L+        FL        T+K   S++E +++AD+ISLH   +
Sbjct: 168  FGATITAYDAYPNKDLD--------FL--------TYK--DSVKEAIKDADIISLHVPAN 209

Query: 911  KTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKP 1090
            K +YHL +      +KK A+LVNA+RG VI+   L++ +    +    +D +E+E     
Sbjct: 210  KESYHLFDKTMFDHVKKGAILVNAARGAVINTPDLIDAVNDGTLLGAAIDTYENEAAYFT 269

Query: 1091 G--------------LAEMKNAVVVPHIA 1135
                           L E +  +V PHIA
Sbjct: 270  NDWTNKDIDDKTLLELIEHERILVTPHIA 298



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>Q8NUT2:LDHD_STAAW D-lactate dehydrogenase - Staphylococcus aureus (strain MW2)|
          Length = 330

 Score = 91.3 bits (225), Expect = 1e-17
 Identities = 74/269 (27%), Positives = 123/269 (45%), Gaps = 14/269 (5%)
 Frame = +2

Query: 371  GQLTEDWGEVLFSALKRAGGTAFSNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTXXXX 550
            G+L +D    ++  L+  G    +    G++  D+D A K+ I I N P    ET     
Sbjct: 55   GKLEDD----VYPKLESYGIKQIAQRTAGFDMYDLDLAKKHNIVISNVPSYSPETIAEYS 110

Query: 551  XXXXXXXXRRIVEADQFMRAGLYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEG 730
                    RR  + ++ ++A  +  W   + +   +K  TV +IG GRIG+A A++   G
Sbjct: 111  VSIALQLVRRFPDIERRVQAHDFT-WQAEI-MSKPVKNMTVAIIGTGRIGAATAKIYA-G 167

Query: 731  FKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLD 910
            F   +  +D Y +  L+        FL        T+K   S++E +++AD+ISLH   +
Sbjct: 168  FGATITAYDAYPNKDLD--------FL--------TYK--DSVKEAIKDADIISLHVPAN 209

Query: 911  KTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKP 1090
            K +YHL +      +KK A+LVNA+RG VI+   L+  +    +    +D +E+E     
Sbjct: 210  KESYHLFDKAMFDHVKKGAILVNAARGAVINTPDLIAAVNDGTLLGAAIDTYENEAAYFT 269

Query: 1091 G--------------LAEMKNAVVVPHIA 1135
                           L E +  +V PHIA
Sbjct: 270  NDWTNKDIDDKTLLELIEHERILVTPHIA 298



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>Q6G6F1:LDHD_STAAS D-lactate dehydrogenase - Staphylococcus aureus (strain MSSA476)|
          Length = 330

 Score = 91.3 bits (225), Expect = 1e-17
 Identities = 74/269 (27%), Positives = 123/269 (45%), Gaps = 14/269 (5%)
 Frame = +2

Query: 371  GQLTEDWGEVLFSALKRAGGTAFSNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTXXXX 550
            G+L +D    ++  L+  G    +    G++  D+D A K+ I I N P    ET     
Sbjct: 55   GKLEDD----VYPKLESYGIKQIAQRTAGFDMYDLDLAKKHNIVISNVPSYSPETIAEYS 110

Query: 551  XXXXXXXXRRIVEADQFMRAGLYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEG 730
                    RR  + ++ ++A  +  W   + +   +K  TV +IG GRIG+A A++   G
Sbjct: 111  VSIALQLVRRFPDIERRVQAHDFT-WQAEI-MSKPVKNMTVAIIGTGRIGAATAKIYA-G 167

Query: 731  FKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLD 910
            F   +  +D Y +  L+        FL        T+K   S++E +++AD+ISLH   +
Sbjct: 168  FGATITAYDAYPNKDLD--------FL--------TYK--DSVKEAIKDADIISLHVPAN 209

Query: 911  KTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKP 1090
            K +YHL +      +KK A+LVNA+RG VI+   L+  +    +    +D +E+E     
Sbjct: 210  KESYHLFDKAMFDHVKKGAILVNAARGAVINTPDLIAAVNDGTLLGAAIDTYENEAAYFT 269

Query: 1091 G--------------LAEMKNAVVVPHIA 1135
                           L E +  +V PHIA
Sbjct: 270  NDWTNKDIDDKTLLELIEHERILVTPHIA 298



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>P72357:LDHD_STAAU D-lactate dehydrogenase - Staphylococcus aureus|
          Length = 330

 Score = 90.5 bits (223), Expect = 2e-17
 Identities = 74/269 (27%), Positives = 122/269 (45%), Gaps = 14/269 (5%)
 Frame = +2

Query: 371  GQLTEDWGEVLFSALKRAGGTAFSNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTXXXX 550
            G+L  D    ++  L+  G    +    G++  D+D A K+ I I N P    ET     
Sbjct: 55   GKLEND----VYPKLESYGIKQIAQRTAGFDMYDLDLAKKHNIVISNVPSYSPETIAEYS 110

Query: 551  XXXXXXXXRRIVEADQFMRAGLYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEG 730
                    RR  + ++ ++A  +  W   + +   +K  TV +IG GRIG+A A++   G
Sbjct: 111  VSIALQLVRRFPDIERRVQAHDFT-WQAEI-MSKPVKNMTVAIIGTGRIGAATAKIYA-G 167

Query: 731  FKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLD 910
            F   +  +D Y +  L+        FL        T+K   S++E +++AD+ISLH   +
Sbjct: 168  FGATITAYDAYPNKDLD--------FL--------TYK--DSVKEAIKDADIISLHVPAN 209

Query: 911  KTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKP 1090
            K +YHL +      +KK A+LVNA+RG VI+   L+  +    +    +D +E+E     
Sbjct: 210  KESYHLFDKAMFDHVKKGAILVNAARGAVINTPDLIAAVNDGTLLGAAIDTYENEAAYFT 269

Query: 1091 G--------------LAEMKNAVVVPHIA 1135
                           L E +  +V PHIA
Sbjct: 270  NDWTNKDIDDKTLLELIEHERILVTPHIA 298



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>Q5HD29:LDHD_STAAC D-lactate dehydrogenase - Staphylococcus aureus (strain COL)|
          Length = 330

 Score = 90.5 bits (223), Expect = 2e-17
 Identities = 74/269 (27%), Positives = 122/269 (45%), Gaps = 14/269 (5%)
 Frame = +2

Query: 371  GQLTEDWGEVLFSALKRAGGTAFSNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTXXXX 550
            G+L  D    ++  L+  G    +    G++  D+D A K+ I I N P    ET     
Sbjct: 55   GKLEND----VYPKLESYGIKQIAQRTAGFDMYDLDLAKKHNIVISNVPSYSPETIAEYS 110

Query: 551  XXXXXXXXRRIVEADQFMRAGLYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEG 730
                    RR  + ++ ++A  +  W   + +   +K  TV +IG GRIG+A A++   G
Sbjct: 111  VSIALQLVRRFPDIERRVQAHDFT-WQAEI-MSKPVKNMTVAIIGTGRIGAATAKIYA-G 167

Query: 731  FKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLD 910
            F   +  +D Y +  L+        FL        T+K   S++E +++AD+ISLH   +
Sbjct: 168  FGATITAYDAYPNKDLD--------FL--------TYK--DSVKEAIKDADIISLHVPAN 209

Query: 911  KTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKP 1090
            K +YHL +      +KK A+LVNA+RG VI+   L+  +    +    +D +E+E     
Sbjct: 210  KESYHLFDKAMFDHVKKGAILVNAARGAVINTPDLIAAVNDGTLLGAAIDTYENEAAYFT 269

Query: 1091 G--------------LAEMKNAVVVPHIA 1135
                           L E +  +V PHIA
Sbjct: 270  NDWTNKDIDDKTLLELIEHERILVTPHIA 298



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>P0A9T3:SERA_SHIFL D-3-phosphoglycerate dehydrogenase - Shigella flexneri|
          Length = 410

 Score = 90.1 bits (222), Expect = 2e-17
 Identities = 70/265 (26%), Positives = 121/265 (45%), Gaps = 6/265 (2%)
 Frame = +2

Query: 434  AFSNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAG 613
            A     +G N VD+DAA K GI + N P   T +             R + EA+     G
Sbjct: 78   AIGCFCIGTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLLLRGVPEANAKAHRG 137

Query: 614  LYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVT 793
            +++      F     +G+ +G+IG G IG+    ++ E   M + ++D+     L     
Sbjct: 138  VWNKLAAGSFEA---RGKKLGIIGYGHIGTQLG-ILAESLGMYVYFYDIENKLPL----- 188

Query: 794  AYGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVL 973
                    N  Q         + ++L  +DV+SLH   + +T +++  + +++MK  ++L
Sbjct: 189  -------GNATQ------VQHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLL 235

Query: 974  VNASRGPVIDEVALVEHLKANPMFRVGLDVFEDE------PYMKPGLAEMKNAVVVPHIA 1135
            +NASRG V+D  AL + L +  +    +DVF  E      P+  P L E  N ++ PHI 
Sbjct: 236  INASRGTVVDIPALCDALASKHLAGAAIDVFPTEPATNSDPFTSP-LCEFDNVLLTPHIG 294

Query: 1136 SASKWTREGMATLAALNVLGKIKGY 1210
             +++  +E +     L V GK+  Y
Sbjct: 295  GSTQEAQENI----GLEVAGKLIKY 315



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>P0A9T0:SERA_ECOLI D-3-phosphoglycerate dehydrogenase - Escherichia coli|
          Length = 410

 Score = 90.1 bits (222), Expect = 2e-17
 Identities = 70/265 (26%), Positives = 121/265 (45%), Gaps = 6/265 (2%)
 Frame = +2

Query: 434  AFSNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAG 613
            A     +G N VD+DAA K GI + N P   T +             R + EA+     G
Sbjct: 78   AIGCFCIGTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLLLRGVPEANAKAHRG 137

Query: 614  LYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVT 793
            +++      F     +G+ +G+IG G IG+    ++ E   M + ++D+     L     
Sbjct: 138  VWNKLAAGSFEA---RGKKLGIIGYGHIGTQLG-ILAESLGMYVYFYDIENKLPL----- 188

Query: 794  AYGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVL 973
                    N  Q         + ++L  +DV+SLH   + +T +++  + +++MK  ++L
Sbjct: 189  -------GNATQ------VQHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLL 235

Query: 974  VNASRGPVIDEVALVEHLKANPMFRVGLDVFEDE------PYMKPGLAEMKNAVVVPHIA 1135
            +NASRG V+D  AL + L +  +    +DVF  E      P+  P L E  N ++ PHI 
Sbjct: 236  INASRGTVVDIPALCDALASKHLAGAAIDVFPTEPATNSDPFTSP-LCEFDNVLLTPHIG 294

Query: 1136 SASKWTREGMATLAALNVLGKIKGY 1210
             +++  +E +     L V GK+  Y
Sbjct: 295  GSTQEAQENI----GLEVAGKLIKY 315



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>P0A9T1:SERA_ECOL6 D-3-phosphoglycerate dehydrogenase - Escherichia coli O6|
          Length = 410

 Score = 90.1 bits (222), Expect = 2e-17
 Identities = 70/265 (26%), Positives = 121/265 (45%), Gaps = 6/265 (2%)
 Frame = +2

Query: 434  AFSNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAG 613
            A     +G N VD+DAA K GI + N P   T +             R + EA+     G
Sbjct: 78   AIGCFCIGTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLLLRGVPEANAKAHRG 137

Query: 614  LYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVT 793
            +++      F     +G+ +G+IG G IG+    ++ E   M + ++D+     L     
Sbjct: 138  VWNKLAAGSFEA---RGKKLGIIGYGHIGTQLG-ILAESLGMYVYFYDIENKLPL----- 188

Query: 794  AYGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVL 973
                    N  Q         + ++L  +DV+SLH   + +T +++  + +++MK  ++L
Sbjct: 189  -------GNATQ------VQHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLL 235

Query: 974  VNASRGPVIDEVALVEHLKANPMFRVGLDVFEDE------PYMKPGLAEMKNAVVVPHIA 1135
            +NASRG V+D  AL + L +  +    +DVF  E      P+  P L E  N ++ PHI 
Sbjct: 236  INASRGTVVDIPALCDALASKHLAGAAIDVFPTEPATNSDPFTSP-LCEFDNVLLTPHIG 294

Query: 1136 SASKWTREGMATLAALNVLGKIKGY 1210
             +++  +E +     L V GK+  Y
Sbjct: 295  GSTQEAQENI----GLEVAGKLIKY 315



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>P0A9T2:SERA_ECO57 D-3-phosphoglycerate dehydrogenase - Escherichia coli O157:H7|
          Length = 410

 Score = 90.1 bits (222), Expect = 2e-17
 Identities = 70/265 (26%), Positives = 121/265 (45%), Gaps = 6/265 (2%)
 Frame = +2

Query: 434  AFSNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAG 613
            A     +G N VD+DAA K GI + N P   T +             R + EA+     G
Sbjct: 78   AIGCFCIGTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLLLRGVPEANAKAHRG 137

Query: 614  LYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVT 793
            +++      F     +G+ +G+IG G IG+    ++ E   M + ++D+     L     
Sbjct: 138  VWNKLAAGSFEA---RGKKLGIIGYGHIGTQLG-ILAESLGMYVYFYDIENKLPL----- 188

Query: 794  AYGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVL 973
                    N  Q         + ++L  +DV+SLH   + +T +++  + +++MK  ++L
Sbjct: 189  -------GNATQ------VQHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLL 235

Query: 974  VNASRGPVIDEVALVEHLKANPMFRVGLDVFEDE------PYMKPGLAEMKNAVVVPHIA 1135
            +NASRG V+D  AL + L +  +    +DVF  E      P+  P L E  N ++ PHI 
Sbjct: 236  INASRGTVVDIPALCDALASKHLAGAAIDVFPTEPATNSDPFTSP-LCEFDNVLLTPHIG 294

Query: 1136 SASKWTREGMATLAALNVLGKIKGY 1210
             +++  +E +     L V GK+  Y
Sbjct: 295  GSTQEAQENI----GLEVAGKLIKY 315



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>P99116:LDHD_STAAN D-lactate dehydrogenase - Staphylococcus aureus (strain N315)|
          Length = 330

 Score = 90.1 bits (222), Expect = 2e-17
 Identities = 74/269 (27%), Positives = 119/269 (44%), Gaps = 14/269 (5%)
 Frame = +2

Query: 371  GQLTEDWGEVLFSALKRAGGTAFSNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTXXXX 550
            G+L  D    ++  L+  G    +    G++  D+D A K+ I I N P    ET     
Sbjct: 55   GKLEND----VYPKLESYGIKQIAQRTAGFDMYDLDLAKKHNIVISNVPSYSPETIAEYS 110

Query: 551  XXXXXXXXRRIVEADQFMRAGLYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEG 730
                    RR  + ++  R   +D       +   +K  TV +IG GRIG+A A++   G
Sbjct: 111  VSIALQLVRRFPDIER--RVQTHDFTWQAEIMSKPVKNMTVAIIGTGRIGAATAKIYA-G 167

Query: 731  FKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLD 910
            F   +  +D Y +  L+        FL        T+K   S++E +++AD+ISLH   +
Sbjct: 168  FGATITAYDAYPNKDLD--------FL--------TYK--DSVKEAIKDADIISLHVPAN 209

Query: 911  KTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKP 1090
            K +YHL +      +KK A+LVNA+RG VI+   L+  +    +    +D +E+E     
Sbjct: 210  KESYHLFDKAMFDHVKKGAILVNAARGAVINTPDLIAAVNDGTLLGAAIDTYENEAAYFT 269

Query: 1091 G--------------LAEMKNAVVVPHIA 1135
                           L E +  +V PHIA
Sbjct: 270  NDWTNKDIDDKTLLELIEHERILVTPHIA 298



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>P63940:LDHD_STAAM D-lactate dehydrogenase - Staphylococcus aureus (strain Mu50 / ATCC|
            700699)
          Length = 330

 Score = 90.1 bits (222), Expect = 2e-17
 Identities = 74/269 (27%), Positives = 119/269 (44%), Gaps = 14/269 (5%)
 Frame = +2

Query: 371  GQLTEDWGEVLFSALKRAGGTAFSNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTXXXX 550
            G+L  D    ++  L+  G    +    G++  D+D A K+ I I N P    ET     
Sbjct: 55   GKLEND----VYPKLESYGIKQIAQRTAGFDMYDLDLAKKHNIVISNVPSYSPETIAEYS 110

Query: 551  XXXXXXXXRRIVEADQFMRAGLYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEG 730
                    RR  + ++  R   +D       +   +K  TV +IG GRIG+A A++   G
Sbjct: 111  VSIALQLVRRFPDIER--RVQTHDFTWQAEIMSKPVKNMTVAIIGTGRIGAATAKIYA-G 167

Query: 731  FKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLD 910
            F   +  +D Y +  L+        FL        T+K   S++E +++AD+ISLH   +
Sbjct: 168  FGATITAYDAYPNKDLD--------FL--------TYK--DSVKEAIKDADIISLHVPAN 209

Query: 911  KTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKP 1090
            K +YHL +      +KK A+LVNA+RG VI+   L+  +    +    +D +E+E     
Sbjct: 210  KESYHLFDKAMFDHVKKGAILVNAARGAVINTPDLIAAVNDGTLLGAAIDTYENEAAYFT 269

Query: 1091 G--------------LAEMKNAVVVPHIA 1135
                           L E +  +V PHIA
Sbjct: 270  NDWTNKDIDDKTLLELIEHERILVTPHIA 298



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>Q59516:DHGY_METEX Glycerate dehydrogenase - Methylobacterium extorquens (Protomonas|
            extorquens)
          Length = 314

 Score = 90.1 bits (222), Expect = 2e-17
 Identities = 72/261 (27%), Positives = 113/261 (43%), Gaps = 6/261 (2%)
 Frame = +2

Query: 449  AVGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGW 628
            A G + VD  AA   GI + N       T             R IV     +R G ++  
Sbjct: 73   ATGTDVVDKAAAKAQGITVVNIRNYAFNTVPEHVVGLMFALRRAIVPYANSVRRGDWNKS 132

Query: 629  LPHLFVGNLL---KGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAY 799
                +    +    G T+G+IG G +G + A+   E   M ++ FD++    L       
Sbjct: 133  KQFCYFDYPIYDIAGSTLGIIGYGALGKSIAKRA-EALGMKVLAFDVFPQDGLV------ 185

Query: 800  GQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVN 979
                               +E +L ++DVI+LH  L   T ++I  E+L  MK+ A+L+N
Sbjct: 186  ------------------DLETILTQSDVITLHVPLTPDTKNMIGAEQLKKMKRSAILIN 227

Query: 980  ASRGPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGL---AEMKNAVVVPHIASASKW 1150
             +RG ++DE AL++ LK   +   G DV   EP     +   A++ N +V PH+A ASK 
Sbjct: 228  TARGGLVDEAALLQALKDGTIGGAGFDVVAQEPPKDGNILCDADLPNLIVTPHVAWASKE 287

Query: 1151 TREGMATLAALNVLGKIKGYP 1213
              + +A     NV   + G P
Sbjct: 288  AMQILADQLVDNVEAFVAGKP 308



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>P87228:SERA_SCHPO Putative D-3-phosphoglycerate dehydrogenase - Schizosaccharomyces|
            pombe (Fission yeast)
          Length = 466

 Score = 88.6 bits (218), Expect = 7e-17
 Identities = 76/296 (25%), Positives = 132/296 (44%), Gaps = 16/296 (5%)
 Frame = +2

Query: 308  KTILSVDDILALI-GDHCHGVIGQ--LTEDWGEVLFSALKRAGGTAFSNMAVGYNNVDVD 478
            KT +S DD++  I G H  G+  +  LT    E   S +            +G N VD+D
Sbjct: 83   KTSMSEDDLVEKIKGVHAIGIRSKTRLTRRVLEAADSLI------VIGCFCIGTNQVDLD 136

Query: 479  AANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLPHLFVGNLL 658
             A + GIA+ N+P   + +             R++ +    +  G ++      +    +
Sbjct: 137  FAAERGIAVFNSPYANSRSVAELVIGYIISLARQVGDRSLELHRGEWNKVSSGCWE---I 193

Query: 659  KGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVT 838
            +G+T+G+IG G IGS  + ++ E   ++++Y+D+     L                    
Sbjct: 194  RGKTLGIIGYGHIGSQLS-VLAEAMGLHVVYYDILPIMPLGSA----------------- 235

Query: 839  WKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALV 1018
             K+ SS+ E+L  AD +SLH      T ++I+ +  A MK+ + L+NASRG V+D  ALV
Sbjct: 236  -KQLSSLPELLHRADFVSLHVPASPETKNMISSKEFAAMKEGSYLINASRGTVVDIPALV 294

Query: 1019 EHLKANPMFRVGLDVFEDEP-------------YMKPGLAEMKNAVVVPHIASASK 1147
            +  K+  +    +DV+  EP                  L   KN ++ PHI  +++
Sbjct: 295  DASKSGKIAGAAIDVYPSEPAGNGKDKFVDSLNSWTSELTHCKNIILTPHIGGSTE 350



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>P51011:LDHD_LEUMC D-lactate dehydrogenase - Leuconostoc mesenteroides subsp. cremoris|
          Length = 331

 Score = 87.8 bits (216), Expect = 1e-16
 Identities = 76/265 (28%), Positives = 120/265 (45%), Gaps = 15/265 (5%)
 Frame = +2

Query: 386  DWGEVLFSALKRAGGTAFSNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXX 565
            D+     +AL   G T  S   VG +N+D DAA +    I N P                
Sbjct: 56   DYTRETLTALANVGVTNLSLRNVGTDNIDFDAAREFNFNISNVPVYSPNAIAEHSMLQLS 115

Query: 566  XXXRRIVEAD-QFMRAGLYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMN 742
               RR    D +  +  L   W P    G  ++ QTVGVIG G IG   A  +++GF   
Sbjct: 116  RLLRRTKALDAKIAKRDLR--WAPT--TGREMRMQTVGVIGTGHIGRV-AINILKGFGAK 170

Query: 743  LIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTY 922
            +I +D Y +  L+    A G ++              +++E+  +AD ISL+       +
Sbjct: 171  VIAYDKYPNAELQ----AEGLYV-------------DTLDELYAQADAISLYVPGVPENH 213

Query: 923  HLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEP--YMKPGL 1096
            HLIN + +A MK   V++NA+RG ++D  A+++ L +  +   G+DV+E+E    MK GL
Sbjct: 214  HLINADAIAKMKDGVVIMNAARGNLMDIDAIIDGLNSGKISDFGMDVYENEVACSMKIGL 273

Query: 1097 AE------------MKNAVVVPHIA 1135
             +             +N ++ PH A
Sbjct: 274  VKNSPDAKIADLIARENVMITPHTA 298



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>P40054:SERA_YEAST D-3-phosphoglycerate dehydrogenase 1 - Saccharomyces cerevisiae|
            (Baker's yeast)
          Length = 469

 Score = 87.4 bits (215), Expect = 2e-16
 Identities = 62/246 (25%), Positives = 119/246 (48%), Gaps = 14/246 (5%)
 Frame = +2

Query: 452  VGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWL 631
            +G N VD+D A   GIA+ N+P   + +             R++ +    +  G ++   
Sbjct: 131  IGTNQVDLDYATSRGIAVFNSPFSNSRSVAELVIAEIISLARQLGDRSIELHTGTWNKVA 190

Query: 632  PHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFL 811
               +    ++G+T+G+IG G IGS  + ++ E   ++++Y+D+         + A G   
Sbjct: 191  ARCWE---VRGKTLGIIGYGHIGSQLS-VLAEAMGLHVLYYDIVT-------IMALG--- 236

Query: 812  KANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRG 991
                    T ++ S+++E+L ++D ++LH      T  +++  + A MK  A ++NASRG
Sbjct: 237  --------TARQVSTLDELLNKSDFVTLHVPATPETEKMLSAPQFAAMKDGAYVINASRG 288

Query: 992  PVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPG--------------LAEMKNAVVVPH 1129
             V+D  +L++ +KAN +    LDV+  EP  K G              L  + N ++ PH
Sbjct: 289  TVVDIPSLIQAVKANKIAGAALDVYPHEP-AKNGEGSFNDELNSWTSELVSLPNIILTPH 347

Query: 1130 IASASK 1147
            I  +++
Sbjct: 348  IGGSTE 353



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>Q8CN22:LDHD_STAES D-lactate dehydrogenase - Staphylococcus epidermidis (strain ATCC|
            12228)
          Length = 330

 Score = 87.4 bits (215), Expect = 2e-16
 Identities = 76/297 (25%), Positives = 130/297 (43%), Gaps = 18/297 (6%)
 Frame = +2

Query: 299  TEKKTILSVDDILALIGDHCHGVIGQLTEDWGEV---LFSALKRAGGTAFSNMAVGYNNV 469
            T    +LSVD +     D      G  T  +G++   ++  L+  G    +    G++  
Sbjct: 29   TTSTELLSVDTV-----DQLKDYDGVTTMQFGKLEPEVYPKLESYGIKQIAQRTAGFDMY 83

Query: 470  DVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLPHLFVG 649
            D++ A K+ I I N P    ET             R+    ++ ++A  +    P   + 
Sbjct: 84   DLELAKKHEIIISNIPSYSPETIAEYSVSIALQLVRKFPTIEKRVQAHNFTWASP--IMS 141

Query: 650  NLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQ 829
              +K  TV +IG GRIG+A  ++   GF   ++ +D Y +  L         FL+     
Sbjct: 142  RPVKNMTVAIIGTGRIGAATGKIYA-GFGARVVGYDAYPNHSLS--------FLEYK--- 189

Query: 830  PVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEV 1009
                    ++E+ +++AD+ISLH   +K ++HL +      +KK AVLVNA+RG VI+  
Sbjct: 190  -------ETVEDAIKDADIISLHVPANKDSFHLFDNNMFKNVKKGAVLVNAARGAVINTP 242

Query: 1010 ALVEHLKANPMFRVGLDVFE---------------DEPYMKPGLAEMKNAVVVPHIA 1135
             L+E +    +    +D +E               D+P +   L   +N +V PHIA
Sbjct: 243  DLIEAVNNGTLSGAAIDTYENEANYFTFDCSNQTIDDPILL-DLIRNENILVTPHIA 298



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>Q5HLA0:LDHD_STAEQ D-lactate dehydrogenase - Staphylococcus epidermidis (strain ATCC|
            35984 / RP62A)
          Length = 330

 Score = 87.4 bits (215), Expect = 2e-16
 Identities = 76/297 (25%), Positives = 130/297 (43%), Gaps = 18/297 (6%)
 Frame = +2

Query: 299  TEKKTILSVDDILALIGDHCHGVIGQLTEDWGEV---LFSALKRAGGTAFSNMAVGYNNV 469
            T    +LSVD +     D      G  T  +G++   ++  L+  G    +    G++  
Sbjct: 29   TTSTELLSVDTV-----DQLKDYDGVTTMQFGKLEPEVYPKLESYGIKQIAQRTAGFDMY 83

Query: 470  DVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLPHLFVG 649
            D++ A K+ I I N P    ET             R+    ++ ++A  +    P   + 
Sbjct: 84   DLELAKKHEIIISNIPSYSPETIAEYSVSIALQLVRKFPTIEKRVQAHNFTWASP--IMS 141

Query: 650  NLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQ 829
              +K  TV +IG GRIG+A  ++   GF   ++ +D Y +  L         FL+     
Sbjct: 142  RPVKNMTVAIIGTGRIGAATGKIYA-GFGARVVGYDAYPNHSLS--------FLEYK--- 189

Query: 830  PVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEV 1009
                    ++E+ +++AD+ISLH   +K ++HL +      +KK AVLVNA+RG VI+  
Sbjct: 190  -------ETVEDAIKDADIISLHVPANKDSFHLFDNNMFKNVKKGAVLVNAARGAVINTP 242

Query: 1010 ALVEHLKANPMFRVGLDVFE---------------DEPYMKPGLAEMKNAVVVPHIA 1135
             L+E +    +    +D +E               D+P +   L   +N +V PHIA
Sbjct: 243  DLIEAVNNGTLSGAAIDTYENEANYFTFDCSNQTIDDPILL-DLIRNENILVTPHIA 298



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>O83080:LDHD_TREPA D-lactate dehydrogenase - Treponema pallidum|
          Length = 331

 Score = 85.5 bits (210), Expect = 6e-16
 Identities = 71/256 (27%), Positives = 108/256 (42%), Gaps = 14/256 (5%)
 Frame = +2

Query: 440  SNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLY 619
            S    G++  +     K+GI + N P                   R   E + F+R   +
Sbjct: 74   STRTAGFDMYNATLLKKHGIRLTNVPSYSPNAIGEYALAAALQLTRHAREIETFVRKRDF 133

Query: 620  DGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAY 799
                P L     L+   VG++G GRIG A AR+  +G    ++ FD Y +   ++++T  
Sbjct: 134  RWQKPIL--SKELRCSRVGILGTGRIGQAAARLF-KGVGAQVVGFDPYPNDAAKEWLTYV 190

Query: 800  GQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVN 979
                              SM+E+L  +DVISLH    K ++HLIN + +A MK    LVN
Sbjct: 191  ------------------SMDELLSTSDVISLHMPATKDSHHLINAKTIAQMKDGVYLVN 232

Query: 980  ASRGPVIDEVALVEHLKANPMFRVGLDVFEDE-PYMKPG-------------LAEMKNAV 1117
             +RG VID  AL++ L    +    LD +E E PY+                L   +  +
Sbjct: 233  TARGAVIDSQALLDSLDKGKIAGAALDAYEFEGPYIPKDNGNNPITDTVYARLVAHERII 292

Query: 1118 VVPHIASASKWTREGM 1165
              PHIA  ++   E M
Sbjct: 293  YTPHIAFYTETAIENM 308



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>Q8DB36:PDXB_VIBVU Erythronate-4-phosphate dehydrogenase - Vibrio vulnificus|
          Length = 377

 Score = 85.1 bits (209), Expect = 7e-16
 Identities = 55/161 (34%), Positives = 88/161 (54%), Gaps = 4/161 (2%)
 Frame = +2

Query: 665  QTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWK 844
            QTVG+IGAG++GS Y +  ++G  + ++  D                F +  G++    +
Sbjct: 118  QTVGIIGAGQVGS-YLQQCLQGIGIKVLIND---------------PFKQEEGDE----R 157

Query: 845  RASSMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVA 1012
              +S++ +L+EADVI+LH  + +     T+HLIN E L  ++ + +L+NA+RGPV+D  A
Sbjct: 158  EFTSLDRLLQEADVITLHTPITRDGKYPTHHLINEEILNSLRADQILINAARGPVVDNQA 217

Query: 1013 LVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIA 1135
            L   L+    F   LDVFE EP +   L  +  A   PH+A
Sbjct: 218  LKRRLQQADGFMAALDVFEFEPEVDMELLPLL-AFATPHVA 257



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>Q47748:VANH_ENTFA D-specific alpha-keto acid dehydrogenase - Enterococcus faecalis|
            (Streptococcus faecalis)
          Length = 323

 Score = 84.7 bits (208), Expect = 1e-15
 Identities = 75/288 (26%), Positives = 119/288 (41%), Gaps = 15/288 (5%)
 Frame = +2

Query: 317  LSVDDILALIGDHCHGVIGQLTEDWGEVLFSALKRAGGTAFSNMAVGYNNVDVDAANKNG 496
            +S D+     G+ C  V G  +E   E    AL++ G    S  ++G N++D  AA + G
Sbjct: 38   ISADNAKLAAGNQCISV-GHKSEV-SEATILALRKVGVKYISTRSIGCNHIDTTAAERMG 95

Query: 497  IAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLPHLFVGNLLKGQTVG 676
            I++G     +  +               I  A   + A     +      G  L+  TVG
Sbjct: 96   ISVGT----VAYSPDSVADYALMLMLMAIRGAKSTIHAVAQQNFRLDCVRGKELRDMTVG 151

Query: 677  VIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASS 856
            VIG G IG A  + +  GF   ++ +D        K    Y Q                 
Sbjct: 152  VIGTGHIGQAVVKRL-RGFGCRVLAYD-----NSRKIEADYVQ----------------- 188

Query: 857  MEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKAN 1036
            ++E+L+ +D+++LH  L   T HLI   ++  MK+ A L+N  RG ++D  +LVE L + 
Sbjct: 189  LDELLKNSDIVTLHVPLCADTRHLIGQRQIGEMKQGAFLINTGRGALVDTGSLVEALGSG 248

Query: 1037 PMFRVGLDVFE---------------DEPYMKPGLAEMKNAVVVPHIA 1135
             +    LDV E               D P++   L  M N ++ PH A
Sbjct: 249  KLGGAALDVLEGEDQFVYTDCSQKVLDHPFLSQ-LLRMPNVIITPHTA 295



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>Q7MIT6:PDXB_VIBVY Erythronate-4-phosphate dehydrogenase - Vibrio vulnificus (strain|
            YJ016)
          Length = 377

 Score = 84.7 bits (208), Expect = 1e-15
 Identities = 54/161 (33%), Positives = 88/161 (54%), Gaps = 4/161 (2%)
 Frame = +2

Query: 665  QTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWK 844
            QTVG++GAG++GS Y +  ++G  + ++  D                F +  G++    +
Sbjct: 118  QTVGIVGAGQVGS-YLQQCLQGIGIKVLIND---------------PFKQEEGDE----R 157

Query: 845  RASSMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVA 1012
              +S++ +L+EADVI+LH  + +     T+HLIN E L  ++ + +L+NA+RGPV+D  A
Sbjct: 158  EFTSLDRLLQEADVITLHTPITRDGKYPTHHLINKEILNSLRADQILINAARGPVVDNQA 217

Query: 1013 LVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIA 1135
            L   L+    F   LDVFE EP +   L  +  A   PH+A
Sbjct: 218  LKHRLQQADGFTAALDVFEFEPEVDMELLPLL-AFATPHVA 257



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>Q8E0N5:LDHD_STRA5 D-lactate dehydrogenase - Streptococcus agalactiae serotype V|
          Length = 330

 Score = 84.7 bits (208), Expect = 1e-15
 Identities = 62/242 (25%), Positives = 108/242 (44%), Gaps = 1/242 (0%)
 Frame = +2

Query: 362  GVIGQLTEDWGEVLFSALKRAGGTAFSNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTX 541
            G+     E   + ++  LK  G    +  + G +  +++ A ++GI I N P    E+  
Sbjct: 47   GIANAQIEPLDDAIYPLLKEMGIKQIAQRSAGVDMYNLELAKQHGIIISNVPSYSPESIA 106

Query: 542  XXXXXXXXXXXRRIVEADQFMRAGLYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMM 721
                       R++      +R   +   LP    G +L   TV +IG GRIG A A++ 
Sbjct: 107  EFTVTIALNLIRKVELIRANVREQNFSWTLP--IRGRVLGNMTVAIIGTGRIGLATAKIF 164

Query: 722  IEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLHP 901
             +GF   +I +D+Y +   +  +                 +  +S+EE + EAD++SLH 
Sbjct: 165  -KGFGCRVIGYDIYHNPMADGIL-----------------EYVNSVEEAVEEADLVSLHM 206

Query: 902  VLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDE-P 1078
                   HL N +     KK A+L+N +RG +++   L+E L    +   G+D +E E P
Sbjct: 207  PPTAENTHLFNLDMFKQFKKGAILMNMARGALVETKDLLEALDQGLLEGAGIDTYEFEGP 266

Query: 1079 YM 1084
            Y+
Sbjct: 267  YI 268



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>P40510:SER33_YEAST D-3-phosphoglycerate dehydrogenase 2 - Saccharomyces cerevisiae|
            (Baker's yeast)
          Length = 469

 Score = 84.3 bits (207), Expect = 1e-15
 Identities = 77/315 (24%), Positives = 144/315 (45%), Gaps = 18/315 (5%)
 Frame = +2

Query: 257  IKLLTDNDCRLEICTEKKTILSVDDILALIGD-HCHGVIGQ--LTEDWGEVLFSALKRAG 427
            IK+  D   ++E     K+ L  D+++  I D H  G+  +  LTE         L+ A 
Sbjct: 72   IKIFKDQGYQVEF---HKSSLPEDELIEKIKDVHAIGIRSKTRLTE-------KILQHAR 121

Query: 428  G-TAFSNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFM 604
                     +G N VD+  A   GIA+ N+P   + +             R++ +    +
Sbjct: 122  NLVCIGCFCIGTNQVDLKYAASKGIAVFNSPFSNSRSVAELVIGEIISLARQLGDRSIEL 181

Query: 605  RAGLYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEK 784
              G ++      +    ++G+T+G+IG G IGS  + ++ E   ++++Y+D+        
Sbjct: 182  HTGTWNKVAARCWE---VRGKTLGIIGYGHIGSQLS-VLAEAMGLHVLYYDIVT------ 231

Query: 785  FVTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKE 964
             + A G           T ++ S+++E+L ++D ++LH      T  +++  + A MK  
Sbjct: 232  -IMALG-----------TARQVSTLDELLNKSDFVTLHVPATPETEKMLSAPQFAAMKDG 279

Query: 965  AVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPG--------------LAE 1102
            A ++NASRG V+D  +L++ +KAN +    LDV+  EP  K G              L  
Sbjct: 280  AYVINASRGTVVDIPSLIQAVKANKIAGAALDVYPHEP-AKNGEGSFNDELNSWTSELVS 338

Query: 1103 MKNAVVVPHIASASK 1147
            + N ++ PHI  +++
Sbjct: 339  LPNIILTPHIGGSTE 353



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>P17584:DHD2_LACPA D-2-hydroxyisocaproate dehydrogenase - Lactobacillus paracasei|
          Length = 333

 Score = 84.3 bits (207), Expect = 1e-15
 Identities = 73/273 (26%), Positives = 120/273 (43%), Gaps = 15/273 (5%)
 Frame = +2

Query: 362  GVIGQLTEDWGEVLFSALKRAGGTAFSNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTX 541
            G+    T  +   +F  +   G    +   VG +N+D+ A  + GI + N P        
Sbjct: 47   GINSLQTTPYAAGVFEKMHAYGIKFLTIRNVGTDNIDMTAMKQYGIRLSNVPAYSPAAIA 106

Query: 542  XXXXXXXXXXXRRIVEADQFMRAGLYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMM 721
                       R + +    ++AG Y+      F+G  L  QTVGV+G G IG   A  +
Sbjct: 107  EFALTDTLYLLRNMGKVQAQLQAGDYEK--AGTFIGKELGQQTVGVMGTGHIGQV-AIKL 163

Query: 722  IEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLH- 898
             +GF   +I +D Y                   G+ P       S+E++ +++DVI LH 
Sbjct: 164  FKGFGAKVIAYDPYPM----------------KGDHPDF--DYVSLEDLFKQSDVIDLHV 205

Query: 899  PVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEP 1078
            P +++ T H+IN     +MK  A+++N +R  +ID  A++ +LK+  +  VG+D +E E 
Sbjct: 206  PGIEQNT-HIINEAAFNLMKPGAIVINTARPNLIDTQAMLSNLKSGKLAGVGIDTYEYET 264

Query: 1079 YMKPGLAE--------------MKNAVVVPHIA 1135
                 LA+              M N V+ PHIA
Sbjct: 265  EDLLNLAKHGSFKDPLWDELLGMPNVVLSPHIA 297



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>Q99ZM2:LDHD_STRP1 D-lactate dehydrogenase - Streptococcus pyogenes serotype M1|
          Length = 330

 Score = 83.6 bits (205), Expect = 2e-15
 Identities = 64/231 (27%), Positives = 106/231 (45%), Gaps = 1/231 (0%)
 Frame = +2

Query: 395  EVLFSALKRAGGTAFSNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXX 574
            + ++  LK  G    +  +   +  ++D A +N I I N P    E+             
Sbjct: 58   DAIYPLLKEMGIKQIAQHSASVDMYNLDLATENDIIITNVPSYSPESIAEFTVTIVLNLI 117

Query: 575  RRIVEADQFMRAGLYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYF 754
            R +    + ++   +   LP    G +L   TV +IG GRIG A A++  +GF   ++ +
Sbjct: 118  RHVELIRENVKKQNFTWGLP--IRGRVLGDMTVAIIGTGRIGLATAKIF-KGFGCKVVGY 174

Query: 755  DLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLIN 934
            D+YQS    K V  Y +                S+EE +++AD++SLH        HL N
Sbjct: 175  DIYQSDAA-KAVLDYKE----------------SVEEAIKDADLVSLHMPPTAENTHLFN 217

Query: 935  PERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDE-PYM 1084
             +     KK A+L+N +RG VI+   L++ L A  +   G+D +E E PY+
Sbjct: 218  SDLFKSFKKGAILMNMARGAVIETQDLLDALDAGLLSGAGIDTYEFEGPYI 268



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>Q05709:VANH_ENTFC D-specific alpha-keto acid dehydrogenase - Enterococcus faecium|
            (Streptococcus faecium)
          Length = 322

 Score = 82.4 bits (202), Expect = 5e-15
 Identities = 74/275 (26%), Positives = 118/275 (42%), Gaps = 19/275 (6%)
 Frame = +2

Query: 368  IGQLTEDWGEVLFSALKRAGGTAFSNMAVGYNNVDVDAANKNGIAIGN---TPGVLTETT 538
            +G  +E    +L  ALKRAG    S  ++G N++D  AA + GI + N   +P  + + T
Sbjct: 53   VGHKSEISASILL-ALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAYSPDSVADYT 111

Query: 539  XXXXXXXXXXXXR--RIVEADQFMRAGLYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAYA 712
                           R VE   F               G +L   TVGV+G G+IG A  
Sbjct: 112  MMLILMAVRNVKSIVRSVEKHDFRLDS---------DRGKVLSDMTVGVVGTGQIGKAVI 162

Query: 713  RMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADVIS 892
               + GF   ++ +   +S  +      Y  F                 +E+L+ +D+++
Sbjct: 163  E-RLRGFGCKVLAYSRSRSIEVN-----YVPF-----------------DELLQNSDIVT 199

Query: 893  LHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFED 1072
            LH  L+  T+++I+ E++  MK+ A L+N  RGP++D   LV+ L+   +    LDV E 
Sbjct: 200  LHVPLNTDTHYIISHEQIQRMKQGAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEG 259

Query: 1073 EP-------YMKP-------GLAEMKNAVVVPHIA 1135
            E          KP        L  M N ++ PH A
Sbjct: 260  EEEFFYSDCTQKPIDNQFLLKLQRMPNVIITPHTA 294



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>Q7N2B2:PDXB_PHOLL Erythronate-4-phosphate dehydrogenase - Photorhabdus luminescens|
            subsp. laumondii
          Length = 375

 Score = 81.3 bits (199), Expect = 1e-14
 Identities = 59/176 (33%), Positives = 94/176 (53%), Gaps = 5/176 (2%)
 Frame = +2

Query: 656  LKGQTVGVIGAGRIGSAYA-RMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQP 832
            LK + VG++G G +GS  A R+ + G +  L         R ++            G+  
Sbjct: 114  LKDKVVGIVGVGNVGSRLAERLAVLGIRTLLC-----DPPRADR------------GDAG 156

Query: 833  VTWKRASSMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVI 1000
              W    S+E++++EAD+++ H  L+K+    T+HL++ E L+++    +L+NASRG VI
Sbjct: 157  EFW----SLEKLVKEADILTFHTPLNKSGPYKTHHLVDVELLSVLPDNRILINASRGEVI 212

Query: 1001 DEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA 1168
            D  AL+  LK     RV LDV+E EP +   L E+ + +  PHIA    +T EG A
Sbjct: 213  DNQALLTALKCGKKLRVVLDVWEPEPDLSLPLLELVD-IGTPHIAG---YTLEGKA 264



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>Q8E6A9:LDHD_STRA3 D-lactate dehydrogenase - Streptococcus agalactiae serotype III|
          Length = 330

 Score = 81.3 bits (199), Expect = 1e-14
 Identities = 59/231 (25%), Positives = 105/231 (45%), Gaps = 1/231 (0%)
 Frame = +2

Query: 395  EVLFSALKRAGGTAFSNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXX 574
            + ++  LK  G    +  + G +  +++ A ++GI I N P    E+             
Sbjct: 58   DAIYPLLKEMGIKQIAQRSAGVDMYNLELAKQHGIIISNVPSYSPESIAEFTVTIALNLI 117

Query: 575  RRIVEADQFMRAGLYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYF 754
            R++      +R   +   LP    G +L   TV +IG GRIG A A++  +GF   +I +
Sbjct: 118  RKVELIRANVREQNFSWTLP--IRGRVLGNMTVAIIGTGRIGLATAKIF-KGFGCRVIGY 174

Query: 755  DLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLIN 934
            D+Y +   +  +                 +  +S+EE + +AD++SLH        HL N
Sbjct: 175  DIYHNPMADGIL-----------------EYVNSVEEAVEKADLVSLHMPPTAENTHLFN 217

Query: 935  PERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDE-PYM 1084
             +     KK A+L+N +RG +++   L+E L    +   G+D +E E PY+
Sbjct: 218  LDMFKQFKKGAILMNMARGALVETKDLLEALDQGLLEGAGIDTYEFEGPYI 268



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>Q88VJ2:LDHD_LACPL D-lactate dehydrogenase - Lactobacillus plantarum|
          Length = 332

 Score = 80.5 bits (197), Expect = 2e-14
 Identities = 65/238 (27%), Positives = 106/238 (44%), Gaps = 7/238 (2%)
 Frame = +2

Query: 383  EDWGEVLFSALKRAGGTAFSNMAVGYNNVDVDAANKNGIAIGNTPGV-------LTETTX 541
            +D+   + + L   G    S   VG +N+DV      G+ I N P         L+ T  
Sbjct: 55   KDYTAEVLNKLADEGVKNISLRNVGVDNLDVPTVKARGLNISNVPAYSPNAIAELSVTQL 114

Query: 542  XXXXXXXXXXXRRIVEADQFMRAGLYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMM 721
                       +++ + D          W P   +   L   TVGVIG GRIG A A  +
Sbjct: 115  MQLLRQTPLFNKKLAKQDF--------RWAPD--IAKELNTMTVGVIGTGRIGRA-AIDI 163

Query: 722  IEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLHP 901
             +GF   +I +D+Y++  LEK     G ++              +++E+  +ADVI+LH 
Sbjct: 164  FKGFGAKVIGYDVYRNAELEK----EGMYV-------------DTLDELYAQADVITLHV 206

Query: 902  VLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDE 1075
               K  YH++N +  + MK  A ++N +RG +ID   L++ L +  +    LD +E E
Sbjct: 207  PALKDNYHMLNADAFSKMKDGAYILNFARGTLIDSEDLIKALDSGKVAGAALDTYEYE 264



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>Q9KQ92:PDXB_VIBCH Erythronate-4-phosphate dehydrogenase - Vibrio cholerae|
          Length = 381

 Score = 78.6 bits (192), Expect = 7e-14
 Identities = 62/199 (31%), Positives = 98/199 (49%), Gaps = 6/199 (3%)
 Frame = +2

Query: 665  QTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWK 844
            +TVG+IGAG++GS Y    + G  M ++  D  +               +A G++    +
Sbjct: 118  KTVGIIGAGQVGS-YLAKCLSGIGMKVLLNDPPK---------------QAQGDE----R 157

Query: 845  RASSMEEVLREADVISLHPVLDK----TTYHLINPERLAMMKKEAVLVNASRGPVIDEVA 1012
              + +E +L++ADVI+LH  + +     T+HLI+   L  ++ + +L+NA+RGPV+D  A
Sbjct: 158  EFTELETLLKQADVITLHTPITRGGEWPTHHLIDAAILEQLRSDQILINAARGPVVDNAA 217

Query: 1013 LVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA--TLAALN 1186
            L   L+    F   LDVFE EP +   L  +  A   PHIA    +  EG A  T    N
Sbjct: 218  LKARLQQGDGFTAVLDVFEFEPQVDMELLPLL-AFATPHIAG---YGLEGKARGTTMIFN 273

Query: 1187 VLGKIKGYPVWGNPNAVEP 1243
               +  G     NP ++ P
Sbjct: 274  SYCEFLGSAHCANPASLLP 292



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>P26298:LDHD_LACPE D-lactate dehydrogenase - Lactobacillus pentosus|
          Length = 332

 Score = 77.0 bits (188), Expect = 2e-13
 Identities = 62/231 (26%), Positives = 103/231 (44%)
 Frame = +2

Query: 383  EDWGEVLFSALKRAGGTAFSNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXX 562
            +D+   + + L   G    S   VG +N+DV      G+ I N P               
Sbjct: 55   KDYTAEVLNKLADEGVKNISLRNVGVDNLDVPTVKARGLNISNVPAYSPNAIAELSVTQL 114

Query: 563  XXXXRRIVEADQFMRAGLYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMN 742
                R+    ++ +    +  W P   +   L   TVGVIG GRIG A A  + +GF   
Sbjct: 115  MQLLRQTPMFNKKLAKQDFR-WAPD--IAKELNTMTVGVIGTGRIGRA-AIDIFKGFGAK 170

Query: 743  LIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTY 922
            +I +D+Y++  LEK     G ++              +++E+  +ADVI+LH    K  Y
Sbjct: 171  VIGYDVYRNAELEK----EGMYV-------------DTLDELYAQADVITLHVPALKDNY 213

Query: 923  HLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDE 1075
            H++N +  + MK  A ++N +RG +ID   L++ L +  +    L  +E E
Sbjct: 214  HMLNADAFSKMKDGAYILNFARGTLIDSEDLIKALDSGKVAGAALVTYEYE 264



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>Q07103:FDH_NEUCR Formate dehydrogenase - Neurospora crassa|
          Length = 375

 Score = 77.0 bits (188), Expect = 2e-13
 Identities = 66/240 (27%), Positives = 111/240 (46%), Gaps = 9/240 (3%)
 Frame = +2

Query: 452  VGYNNVDVDAANKN--GIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDG 625
            +G ++VD++AANK   GI +    G    +             R  V A + ++ G +D 
Sbjct: 94   IGSDHVDLNAANKTNGGITVAEVTGSNVVSVAEHVLMTILVLVRNFVPAHEQIQEGRWD- 152

Query: 626  WLPHLFVGNL-LKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYG 802
             +         L+G+ VG +G GRIG    R +       L+Y+D YQ    EK      
Sbjct: 153  -VAEAAKNEFDLEGKVVGTVGVGRIGERVLRRLKPFDCKELLYYD-YQPLSAEK------ 204

Query: 803  QFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNA 982
                   E  +  +R + +EE+L + DV++++  L + T  L N E ++ MKK + LVN 
Sbjct: 205  -------EAEIGCRRVADLEEMLAQCDVVTINCPLHEKTQGLFNKELISKMKKGSWLVNT 257

Query: 983  SRGPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKP-GLAEMKNA-----VVVPHIASAS 1144
            +RG ++ +  + E LK+  +   G DV+  +P  +   L   KN       +VPH++  S
Sbjct: 258  ARGAIVVKEDVAEALKSGHLRGYGGDVWFPQPAPQDHPLRYAKNPFGGGNAMVPHMSGTS 317



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>Q9I3W9:PDXB_PSEAE Erythronate-4-phosphate dehydrogenase - Pseudomonas aeruginosa|
          Length = 380

 Score = 75.5 bits (184), Expect = 6e-13
 Identities = 58/167 (34%), Positives = 82/167 (49%), Gaps = 4/167 (2%)
 Frame = +2

Query: 656  LKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPV 835
            L  +T GV+GAG++G     ++  G    ++  D  +  R        G+F+        
Sbjct: 114  LAERTYGVVGAGQVGGRLVEVL-RGLGWKVLVCDPPRQAREPD-----GEFV-------- 159

Query: 836  TWKRASSMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVID 1003
                  S+E +L EADVISLH  L++     T HL++  RLA ++    LVNASRG V+D
Sbjct: 160  ------SLERLLAEADVISLHTPLNRDGEHPTRHLLDEPRLAALRPGTWLVNASRGAVVD 213

Query: 1004 EVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASAS 1144
              AL   L+      V LDV+E EP   P LA  +  +  PHIA  S
Sbjct: 214  NQALRRLLEGGADLEVALDVWEGEPQADPELA-ARCLIATPHIAGYS 259



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>Q87MN8:PDXB_VIBPA Erythronate-4-phosphate dehydrogenase - Vibrio parahaemolyticus|
          Length = 377

 Score = 75.1 bits (183), Expect = 8e-13
 Identities = 50/161 (31%), Positives = 85/161 (52%), Gaps = 4/161 (2%)
 Frame = +2

Query: 665  QTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWK 844
            +TVG+IGAG++GS Y    ++G  +N++  D +                K     P ++ 
Sbjct: 118  KTVGIIGAGQVGS-YLEKCLKGMGINVLINDPF----------------KQEAGDPRSF- 159

Query: 845  RASSMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVA 1012
              + + E++ ++D+I+LH  + K     T+HLI+ + L  ++ + +L+NA+RGPV+D  A
Sbjct: 160  --TPLAELIEQSDIITLHTPITKDGLHPTHHLIDEKVLNGLRGDQILINAARGPVVDNQA 217

Query: 1013 LVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIA 1135
            L + L     F   LDVFE EP +   L  +  A   PH+A
Sbjct: 218  LKQRLMKQDGFTAALDVFEFEPEVDMELLPLL-AFATPHVA 257



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>Q8ECR2:PDXB_SHEON Erythronate-4-phosphate dehydrogenase - Shewanella oneidensis|
          Length = 376

 Score = 73.6 bits (179), Expect = 2e-12
 Identities = 55/167 (32%), Positives = 83/167 (49%), Gaps = 4/167 (2%)
 Frame = +2

Query: 656  LKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPV 835
            L+G+ VG++GAG  GSA A+ + E F + ++  D  +               +A G+   
Sbjct: 115  LRGKVVGIVGAGNTGSATAKCL-EAFGIKVLLNDPIK---------------EAEGDP-- 156

Query: 836  TWKRASSMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVID 1003
              +   S+E +L+EAD+ISLH  + +T    T HL +  RL  +K    L+N  RG VID
Sbjct: 157  --RDFVSLETLLQEADIISLHVPITRTGEHKTLHLFDEARLMSLKANIWLINCCRGDVID 214

Query: 1004 EVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASAS 1144
              AL++  +     ++ LDV+E EP   P L         PHIA  S
Sbjct: 215  NQALIKVKQQRDDLKLVLDVWEGEPNPMPELVPFAE-FATPHIAGYS 260



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>Q884R9:PDXB_PSESM Erythronate-4-phosphate dehydrogenase - Pseudomonas syringae pv.|
            tomato
          Length = 380

 Score = 73.6 bits (179), Expect = 2e-12
 Identities = 57/168 (33%), Positives = 87/168 (51%), Gaps = 5/168 (2%)
 Frame = +2

Query: 656  LKGQTVGVIGAGRIGSAY-ARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQP 832
            L+ +T GV+GAG++G    A +   G+K+ L+     QS     FV              
Sbjct: 114  LRQRTYGVVGAGQVGGRLIAVLKALGWKV-LVCDPPRQSAEGGDFV-------------- 158

Query: 833  VTWKRASSMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVI 1000
                   S++E+L+  DVISLH  LDK+    T+HL++  RL  +++ A L+NASRG V+
Sbjct: 159  -------SLDEILQRCDVISLHTPLDKSGQSPTWHLLDEARLRQLRQGAWLINASRGAVV 211

Query: 1001 DEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASAS 1144
            D  AL + +      +  LDV+E EP +   LA++   +  PHIA  S
Sbjct: 212  DNRALHDVMLEREDLQAVLDVWEGEPQVNVALADL-CVIGTPHIAGYS 258



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>Q88L20:PDXB_PSEPK Erythronate-4-phosphate dehydrogenase - Pseudomonas putida (strain|
            KT2440)
          Length = 380

 Score = 73.6 bits (179), Expect = 2e-12
 Identities = 59/171 (34%), Positives = 85/171 (49%), Gaps = 5/171 (2%)
 Frame = +2

Query: 647  GNLLKGQTVGVIGAGRIGSAYARMMIE-GFKMNLIYFDLYQSTRLEKFVTAYGQFLKANG 823
            G  L  +  GV+GAG +G    R++   G+K+ L+   L Q+     +V           
Sbjct: 111  GVALPERVYGVVGAGEVGGRLVRVLHGLGWKV-LVCDPLRQAAEGGDYV----------- 158

Query: 824  EQPVTWKRASSMEEVLREADVISLHPVLDK----TTYHLINPERLAMMKKEAVLVNASRG 991
                      S+E +L++ DVISLH  L +     T+HL+   +LA ++  A LVNASRG
Sbjct: 159  ----------SLETILQQCDVISLHTPLQRGGQHPTWHLLGQAQLAQLRPGAWLVNASRG 208

Query: 992  PVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASAS 1144
            PV+D VAL E L         LDV+E EP +   LA++   +  PHIA  S
Sbjct: 209  PVVDNVALRELLLDREDVHAVLDVWEGEPQVDLQLADL-CTLATPHIAGYS 258



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>Q668W7:PDXB_YERPS Erythronate-4-phosphate dehydrogenase - Yersinia pseudotuberculosis|
          Length = 375

 Score = 71.2 bits (173), Expect = 1e-11
 Identities = 59/180 (32%), Positives = 89/180 (49%), Gaps = 6/180 (3%)
 Frame = +2

Query: 647  GNLLKGQTVGVIGAGRIGSAY-ARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANG 823
            G  L+ +TVG+IG G +GS   AR+   G +  L         R ++            G
Sbjct: 111  GFQLRDKTVGIIGVGNVGSRLNARLQALGVRTLLC-----DPPRADR------------G 153

Query: 824  EQPVTWKRASSMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRG 991
            +    W     +E+++READV++ H  L+KT    + H+ + E LA +    +L+NA RG
Sbjct: 154  DNEAFWP----LEKLVREADVLTFHTPLNKTGAYQSLHMADDELLAALPDGRILINACRG 209

Query: 992  PVIDEVALVEHLKANPMFRVGLDVFEDEPYMK-PGLAEMKNAVVVPHIASASKWTREGMA 1168
             V+D  AL+  L+      V LDV+E EP +  P LA +   +  PHIA    +T EG A
Sbjct: 210  AVVDNAALLRALEKGKKLSVVLDVWEPEPDLSLPLLARVD--IGTPHIAG---YTLEGKA 264



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>Q8D0U3:PDXB_YERPE Erythronate-4-phosphate dehydrogenase - Yersinia pestis|
          Length = 375

 Score = 71.2 bits (173), Expect = 1e-11
 Identities = 59/180 (32%), Positives = 89/180 (49%), Gaps = 6/180 (3%)
 Frame = +2

Query: 647  GNLLKGQTVGVIGAGRIGSAY-ARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANG 823
            G  L+ +TVG+IG G +GS   AR+   G +  L         R ++            G
Sbjct: 111  GFQLRDKTVGIIGVGNVGSRLNARLQALGVRTLLC-----DPPRADR------------G 153

Query: 824  EQPVTWKRASSMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRG 991
            +    W     +E+++READV++ H  L+KT    + H+ + E LA +    +L+NA RG
Sbjct: 154  DNEAFWP----LEKLVREADVLTFHTPLNKTGAYQSLHMADDELLAALPDGRILINACRG 209

Query: 992  PVIDEVALVEHLKANPMFRVGLDVFEDEPYMK-PGLAEMKNAVVVPHIASASKWTREGMA 1168
             V+D  AL+  L+      V LDV+E EP +  P LA +   +  PHIA    +T EG A
Sbjct: 210  AVVDNAALLRALEKGKKLSVVLDVWEPEPDLSLPLLARVD--IGTPHIAG---YTLEGKA 264



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>Q9SXP2:FDH1_ORYSJ Formate dehydrogenase 1, mitochondrial precursor - Oryza sativa|
            subsp. japonica (Rice)
          Length = 376

 Score = 71.2 bits (173), Expect = 1e-11
 Identities = 61/233 (26%), Positives = 105/233 (45%), Gaps = 2/233 (0%)
 Frame = +2

Query: 452  VGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWL 631
            +G +++D+ AA   G+ +    G  T +             R  +   Q +  G ++   
Sbjct: 120  IGSDHIDLPAAAAAGLTVAEVTGSNTVSVAEDELMRILILLRNFLPGYQQVVHGEWNV-A 178

Query: 632  PHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFD-LYQSTRLEKFVTAYGQF 808
               +    L+G+TVG +GAGRIG    + + + F  NL+Y D L     LEK + A    
Sbjct: 179  GIAYRAYDLEGKTVGTVGAGRIGRLLLQRL-KPFNCNLLYHDRLKIDPELEKEIGA---- 233

Query: 809  LKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASR 988
                       K    ++ +L + DVI ++  L + T  + N ER+A MKK  ++VN +R
Sbjct: 234  -----------KYEEDLDAMLPKCDVIVINTPLTEKTRGMFNKERIAKMKKGVIIVNNAR 282

Query: 989  GPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKP-GLAEMKNAVVVPHIASAS 1144
            G ++D  A+ +   +  +   G DV+  +P  K      M N  + PHI+  +
Sbjct: 283  GAIMDTQAVADACSSGQVAGYGGDVWFPQPAPKDHPWRYMPNHAMTPHISGTT 335



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>P60802:PDXB_SALTY Erythronate-4-phosphate dehydrogenase - Salmonella typhimurium|
          Length = 378

 Score = 70.9 bits (172), Expect = 1e-11
 Identities = 54/178 (30%), Positives = 88/178 (49%), Gaps = 4/178 (2%)
 Frame = +2

Query: 647  GNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGE 826
            G  L+ +T+G++G G +GS   +  +E   +  +  D  ++ R ++     G F      
Sbjct: 111  GFSLRDRTIGIVGVGNVGSRL-QTRLEALGIRTLLCDPPRAARGDE-----GDF------ 158

Query: 827  QPVTWKRASSMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGP 994
                     +++E+++EADV++ H  L K     T HL +   +  +K  A+L+NA RGP
Sbjct: 159  --------RTLDELVQEADVLTFHTPLYKDGPYKTLHLADETLIRRLKPGAILINACRGP 210

Query: 995  VIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA 1168
            V+D  AL+  L A     V LDV+E EP +   L E  + +   HIA    +T EG A
Sbjct: 211  VVDNAALLARLNAGQPLSVVLDVWEGEPDLNVALLEAVD-IGTSHIAG---YTLEGKA 264



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>P60801:PDXB_SALTI Erythronate-4-phosphate dehydrogenase - Salmonella typhi|
          Length = 378

 Score = 70.9 bits (172), Expect = 1e-11
 Identities = 54/178 (30%), Positives = 88/178 (49%), Gaps = 4/178 (2%)
 Frame = +2

Query: 647  GNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGE 826
            G  L+ +T+G++G G +GS   +  +E   +  +  D  ++ R ++     G F      
Sbjct: 111  GFSLRDRTIGIVGVGNVGSRL-QTRLEALGIRTLLCDPPRAARGDE-----GDF------ 158

Query: 827  QPVTWKRASSMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGP 994
                     +++E+++EADV++ H  L K     T HL +   +  +K  A+L+NA RGP
Sbjct: 159  --------RTLDELVQEADVLTFHTPLYKDGPYKTLHLADETLIRRLKPGAILINACRGP 210

Query: 995  VIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA 1168
            V+D  AL+  L A     V LDV+E EP +   L E  + +   HIA    +T EG A
Sbjct: 211  VVDNAALLARLNAGQPLSVVLDVWEGEPDLNVALLEAVD-IGTSHIAG---YTLEGKA 264



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>Q9ZRI8:FDH_HORVU Formate dehydrogenase, mitochondrial precursor - Hordeum vulgare|
            (Barley)
          Length = 377

 Score = 70.5 bits (171), Expect = 2e-11
 Identities = 59/234 (25%), Positives = 106/234 (45%), Gaps = 3/234 (1%)
 Frame = +2

Query: 452  VGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYD-GW 628
            +G +++D+ AA   G+ +    G  T +             R  +   Q +  G ++   
Sbjct: 121  IGSDHIDLPAAAAAGLTVARVTGSNTVSVAEDELMRILILLRNFLPGYQQVVKGEWNVAG 180

Query: 629  LPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQ-STRLEKFVTAYGQ 805
            + H      L+G+TVG +GAGR G    + + + F  NL+Y D  Q +  LEK + A   
Sbjct: 181  IAHRAYD--LEGKTVGTVGAGRYGRLLLQRL-KPFNCNLLYHDRLQINPELEKEIGA--- 234

Query: 806  FLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNAS 985
                        K    ++ +L + DV+ ++  L + T  + N E++A MKK  ++VN +
Sbjct: 235  ------------KFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGVIIVNNA 282

Query: 986  RGPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKP-GLAEMKNAVVVPHIASAS 1144
            RG ++D  A+ +   +  +   G DV+  +P  K      M N  + PHI+  +
Sbjct: 283  RGAIMDTQAVADACSSGHIAGYGGDVWFPQPAPKDHPWRYMPNHAMTPHISGTT 336



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>Q8D2P6:PDXB_WIGBR Erythronate-4-phosphate dehydrogenase - Wigglesworthia glossinidia|
            brevipalpis
          Length = 378

 Score = 68.2 bits (165), Expect = 9e-11
 Identities = 68/249 (27%), Positives = 106/249 (42%), Gaps = 5/249 (2%)
 Frame = +2

Query: 413  LKRAGGTAFSNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEA 592
            LK +      +   G ++VDVD   KN I     PG                    +  A
Sbjct: 54   LKNSNIKFIGSATSGKDHVDVDWLKKNKINFDFAPGC-----------------NSVAVA 96

Query: 593  DQFMRAGLYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIE-GFKMNLIYFDLYQS 769
            +    + LY  +       +LLK +TVG++G G IG    + +   G K  L    L + 
Sbjct: 97   EYVFSSMLYFAYRDKF---SLLK-KTVGIVGFGNIGKCLNKKLSAIGVKTILCDPILEEK 152

Query: 770  TRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKT----TYHLINP 937
              +                      +  S+ E+++ +D+I+LH  L  +    T+HLIN 
Sbjct: 153  NNI----------------------KLKSLNEIVQNSDIITLHVPLTYSGKYPTWHLINK 190

Query: 938  ERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAV 1117
            + L  +K   +L+N SRG VID  +L+  LK     RV LDV+E+EP +   L  + + +
Sbjct: 191  KILLDLKDNCILINTSRGSVIDNNSLLNILKEGKPIRVVLDVWENEPLICSKLLSLID-I 249

Query: 1118 VVPHIASAS 1144
              PHIA  S
Sbjct: 250  GTPHIAGHS 258



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>Q56733:PDXB_SHEVI Erythronate-4-phosphate dehydrogenase - Shewanella violacea|
          Length = 274

 Score = 67.8 bits (164), Expect = 1e-10
 Identities = 52/167 (31%), Positives = 80/167 (47%), Gaps = 4/167 (2%)
 Frame = +2

Query: 656  LKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPV 835
            LK +TVG++GAG  GSA A+ +       L++  + Q +    F+               
Sbjct: 2    LKDKTVGIVGAGNTGSAVAKCLQAYGVTVLLHDPVIQDSDPRDFI--------------- 46

Query: 836  TWKRASSMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVID 1003
                  S++E++   DVISLH  + KT    T++L +  RL  +K    L+N  RG VID
Sbjct: 47   ------SLDELIARCDVISLHVPIIKTGEHKTWYLFDETRLNSLKPGTWLLNCCRGEVID 100

Query: 1004 EVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASAS 1144
              AL++  +  P  ++ LDV+E EP     L  +   +  PHIA  S
Sbjct: 101  NRALIKVKQQRPDIKLVLDVWEGEPNPMHELIPLVE-LATPHIAGYS 146



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>Q07511:FDH_SOLTU Formate dehydrogenase, mitochondrial precursor - Solanum tuberosum|
            (Potato)
          Length = 381

 Score = 67.4 bits (163), Expect = 2e-10
 Identities = 57/234 (24%), Positives = 106/234 (45%), Gaps = 3/234 (1%)
 Frame = +2

Query: 452  VGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYD-GW 628
            +G ++VD+ AA   G+ +    G  T +             R  +     +  G ++   
Sbjct: 125  IGSDHVDLKAAAAAGLTVAEVTGSNTVSVAEDELMRILILVRNFLPGHHQVINGEWNVAA 184

Query: 629  LPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFD-LYQSTRLEKFVTAYGQ 805
            + H      L+G+TVG +GAGRIG    + + + F  NL+Y D L   + LE  + A   
Sbjct: 185  IAHRAYD--LEGKTVGTVGAGRIGRLLLQRL-KPFNCNLLYHDRLKMDSELENQIGA--- 238

Query: 806  FLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNAS 985
                        K    ++++L + D++ ++  L + T  + + ER+A +KK  ++VN +
Sbjct: 239  ------------KFEEDLDKMLSKCDIVVINTPLTEKTKGMFDKERIAKLKKGVLIVNNA 286

Query: 986  RGPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKP-GLAEMKNAVVVPHIASAS 1144
            RG ++D  A+V+   +  +     DV+  +P  K      M N  + PHI+  +
Sbjct: 287  RGAIMDTQAVVDACNSGHIAGYSGDVWYPQPAPKDHPWRYMPNQAMTPHISGTT 340



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>Q56731:PDXB_SHESP Erythronate-4-phosphate dehydrogenase - Shewanella sp. (strain|
            DB6705)
          Length = 274

 Score = 67.0 bits (162), Expect = 2e-10
 Identities = 52/167 (31%), Positives = 80/167 (47%), Gaps = 4/167 (2%)
 Frame = +2

Query: 656  LKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPV 835
            LK +TVG++GAG  GSA A+ +       L++  + Q +    F+               
Sbjct: 2    LKDKTVGIVGAGNTGSAVAKCLQAYGVTVLLHDPVIQDSDPRDFI--------------- 46

Query: 836  TWKRASSMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVID 1003
                  S++E++   DVISLH  + KT    T++L +  RL  +K+   L+N  RG VID
Sbjct: 47   ------SLDELIACCDVISLHVPITKTGEHKTWYLFDEARLNSLKQGTWLLNCCRGEVID 100

Query: 1004 EVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASAS 1144
              AL++     P  ++ LDV+E EP     L  +   +  PHIA  S
Sbjct: 101  NQALIKVKLERPDIKLVLDVWEGEPNPMHELIPLVE-LATPHIAGYS 146



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>Q8A2E4:PDXB_BACTN Erythronate-4-phosphate dehydrogenase - Bacteroides thetaiotaomicron|
          Length = 348

 Score = 67.0 bits (162), Expect = 2e-10
 Identities = 64/226 (28%), Positives = 97/226 (42%), Gaps = 15/226 (6%)
 Frame = +2

Query: 668  TVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKR 847
            T+G+IG G +GS  A++  + F M ++  DL    R EK             E  +T+  
Sbjct: 119  TIGIIGVGNVGSKVAKVA-QDFGMRVLLNDL---PREEK-------------EGNITF-- 159

Query: 848  ASSMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVAL 1015
             +S+E++  E D+I+ H  L K     TYHL +      ++++ V++N SRG VI+  AL
Sbjct: 160  -TSLEKIAEECDIITFHVPLYKEGKYKTYHLADGNFFRSLQRKPVVINTSRGEVIETNAL 218

Query: 1016 VEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLG 1195
            +E +    +    +DV+E EP +   L E K  +  PHIA                    
Sbjct: 219  LEAINNGIISDAVIDVWEHEPEINRELLE-KVLIGTPHIA-------------------- 257

Query: 1196 KIKGYPVWGNPNAVEPFLDE-----------EATPPPACPSIVNAK 1300
               GY   G  NA    LD            E TPP     ++ AK
Sbjct: 258  ---GYSADGKANATRMSLDSICRFFHLSATYEITPPAPSSPLIEAK 300



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>Q67U69:FDH2_ORYSJ Formate dehydrogenase 2, mitochondrial precursor - Oryza sativa|
            subsp. japonica (Rice)
          Length = 378

 Score = 66.2 bits (160), Expect = 4e-10
 Identities = 59/234 (25%), Positives = 103/234 (44%), Gaps = 3/234 (1%)
 Frame = +2

Query: 452  VGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYD-GW 628
            VG +++D+ AA   G+ +    G  T +             R  +     +  G ++   
Sbjct: 122  VGSDHIDLPAAAAAGLTVAEITGSNTVSVAEDQLMRILLLLRNFLPGHHQIVNGEWNVAG 181

Query: 629  LPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQ-STRLEKFVTAYGQ 805
            + H      L+G+TVG +GAGRIG    + + + F  NL+Y D  +    LEK + A   
Sbjct: 182  IAHRTYD--LEGKTVGTVGAGRIGRLLLQRL-KPFNCNLMYHDRVKIDPELEKEIGA--- 235

Query: 806  FLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNAS 985
                        K    ++ +L + DV+ ++  L + T  + N ER+A MKK   +VN +
Sbjct: 236  ------------KYEEDLDAMLPKCDVVVINMPLTEKTRGMFNKERIAKMKKGVTIVNNA 283

Query: 986  RGPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKP-GLAEMKNAVVVPHIASAS 1144
            RG ++D  A+ +   +  +   G DV+  +P  K      M N  + PH +  +
Sbjct: 284  RGAIMDTQAVADACASGHVAGYGGDVWFPQPAPKDHPWRYMPNHAMTPHCSGTT 337



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>P0C1E9:YPRB2_CORML Uncharacterized protein in proB 3'region - Corynebacterium|
            melassecola
          Length = 304

 Score = 65.9 bits (159), Expect = 5e-10
 Identities = 43/111 (38%), Positives = 55/111 (49%), Gaps = 1/111 (0%)
 Frame = +2

Query: 860  EEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANP 1039
            E V  EADV  L   L   TY ++N E L  MK  AVLVN  RGP+I+   LV+ L    
Sbjct: 175  EHVWAEADVFVLILPLTDATYQIVNAETLGKMKPSAVLVNVGRGPLINTDDLVDALNNGT 234

Query: 1040 MFRVGLDVFEDEPYM-KPGLAEMKNAVVVPHIASASKWTREGMATLAALNV 1189
            +    LDV + EP      L EM N V+ PH A+ ++  R     L   N+
Sbjct: 235  IAGAALDVTDPEPLPDSHPLWEMDNVVITPHTANTNERIRALTGELTLRNI 285



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>P0C1E8:Y2355_CORGL Uncharacterized protein Cgl2355/cg2587 - Corynebacterium glutamicum|
            (Brevibacterium flavum)
          Length = 304

 Score = 64.7 bits (156), Expect = 1e-09
 Identities = 42/111 (37%), Positives = 55/111 (49%), Gaps = 1/111 (0%)
 Frame = +2

Query: 860  EEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANP 1039
            E V  EADV  L   L   TY ++N E L  MK  AV+VN  RGP+I+   LV+ L    
Sbjct: 175  EHVWAEADVFVLILPLTDATYQIVNAETLGKMKPSAVVVNVGRGPLINTDDLVDALNNGT 234

Query: 1040 MFRVGLDVFEDEPYM-KPGLAEMKNAVVVPHIASASKWTREGMATLAALNV 1189
            +    LDV + EP      L EM N V+ PH A+ ++  R     L   N+
Sbjct: 235  IAGAALDVTDPEPLPDSHPLWEMDNVVITPHTANTNERIRALTGELTLRNI 285



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>Q6D2N5:PDXB_ERWCT Erythronate-4-phosphate dehydrogenase - Erwinia carotovora subsp.|
            atroseptica (Pectobacterium atrosepticum)
          Length = 378

 Score = 64.3 bits (155), Expect = 1e-09
 Identities = 73/273 (26%), Positives = 113/273 (41%), Gaps = 5/273 (1%)
 Frame = +2

Query: 365  VIGQLTEDWGEVLFSALKRAGGTAFSNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTXX 544
            ++  +T+    +LF +  +  G+A      G ++VD    N NGIA    PG        
Sbjct: 42   MVRSVTKVNANLLFGSSVKFVGSA----TAGTDHVDDTWLNANGIAFSAAPGC----NAI 93

Query: 545  XXXXXXXXXXRRIVEADQFMRAGLYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAY-ARMM 721
                        + E D F                  L+ +TVG++G G +G     R+ 
Sbjct: 94   AVVEYVFSSLLMLAERDGFQ-----------------LRDKTVGIVGVGNVGRRLDTRLK 136

Query: 722  IEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLHP 901
              G K  L   D  ++ R +      G FL              S+E ++R+AD+++LH 
Sbjct: 137  AWGVKTLLC--DPPRADRGDA-----GDFL--------------SLETLVRDADILTLHT 175

Query: 902  VL----DKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFE 1069
             L       T+HL++   L       +L+NA RGPV+D  AL+E L+      V LDV+E
Sbjct: 176  PLYLDGPYRTHHLVDATVLNAFADGRILINACRGPVVDNAALLEALQQGKKLSVILDVWE 235

Query: 1070 DEPYMKPGLAEMKNAVVVPHIASASKWTREGMA 1168
             EP +   L    + +   HIA    +T EG A
Sbjct: 236  PEPGLSTDLLARVD-IGTAHIAG---YTLEGKA 264



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>Q03134:FDH_EMENI Probable formate dehydrogenase - Emericella nidulans (Aspergillus|
            nidulans)
          Length = 377

 Score = 64.3 bits (155), Expect = 1e-09
 Identities = 62/233 (26%), Positives = 99/233 (42%), Gaps = 21/233 (9%)
 Frame = +2

Query: 452  VGYNNVDVDAANKN--GIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDG 625
            +G ++VD+DAANK   GI +    G    +             R  V A   +R G    
Sbjct: 89   IGSDHVDLDAANKTNGGITVAEVTGSNVVSVAEHVVMTILLLVRNFVPAHDQIRNG---D 145

Query: 626  WLPHLFVGNL--LKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAY 799
            W       N   L+ + VG +G GRIG    R +       L+Y+D YQ  R E      
Sbjct: 146  WNVAAVAKNEFDLENKVVGTVGVGRIGERVLRRLKPFDCKELLYYD-YQPLRPEV----- 199

Query: 800  GQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMK------- 958
                    E+ +  +R  S+EE++ + DV++++  L + T  L N E ++ MK       
Sbjct: 200  --------EKEIGARRVDSLEEMVSQCDVVTINCPLHEKTRGLFNKELISKMKPGKSALL 251

Query: 959  ----------KEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEPYMK 1087
                      K + LVN +RG ++ +  + E LK+  +   G DV+  +P  K
Sbjct: 252  YLIIPMLMYHKGSWLVNTARGAIVVKEDVAEALKSGHLRGYGGDVWFPQPAPK 304



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>Q9S7E4:FDH_ARATH Formate dehydrogenase, mitochondrial precursor - Arabidopsis thaliana|
            (Mouse-ear cress)
          Length = 384

 Score = 64.3 bits (155), Expect = 1e-09
 Identities = 46/165 (27%), Positives = 82/165 (49%), Gaps = 2/165 (1%)
 Frame = +2

Query: 656  LKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFD-LYQSTRLEKFVTAYGQFLKANGEQP 832
            L+G+T+G +GAGRIG    + + + F  NL+Y D L  +  LEK   A            
Sbjct: 195  LEGKTIGTVGAGRIGKLLLQRL-KPFGCNLLYHDRLQMAPELEKETGA------------ 241

Query: 833  VTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVA 1012
               K    + E+L + DVI ++  L + T  + N E +  +KK  ++VN +RG +++  A
Sbjct: 242  ---KFVEDLNEMLPKCDVIVINMPLTEKTRGMFNKELIGKLKKGVLIVNNARGAIMERQA 298

Query: 1013 LVEHLKANPMFRVGLDVFEDEPYMKP-GLAEMKNAVVVPHIASAS 1144
            +V+ +++  +     DV++ +P  K      M N  + PH +  +
Sbjct: 299  VVDAVESGHIGGYSGDVWDPQPAPKDHPWRYMPNQAMTPHTSGTT 343



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>Q6LNU2:PDXB_PHOPR Erythronate-4-phosphate dehydrogenase - Photobacterium profundum|
            (Photobacterium sp. (strain SS9))
          Length = 391

 Score = 63.2 bits (152), Expect = 3e-09
 Identities = 49/166 (29%), Positives = 80/166 (48%), Gaps = 9/166 (5%)
 Frame = +2

Query: 665  QTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWK 844
            +T+G+IGAG +GS Y    ++   +  +  D  +                   EQ    +
Sbjct: 118  KTIGIIGAGNVGS-YLAQCLDALGIPYLLNDPIK-------------------EQEGDTR 157

Query: 845  RASSMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVA 1012
            +  S+E +  + DVI++H  + K     T+HLIN   +  ++ +A+L+NA+RGPV D  A
Sbjct: 158  QFHSLEAIKAQCDVITVHTPITKDGEYPTHHLINEAFIDALQPDAILINAARGPVTDNQA 217

Query: 1013 LVEHLKAN-----PMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIA 1135
            L + L+ +           LDVFE EP++   L  +  A   PHIA
Sbjct: 218  LKKALQLSQSGLGKKLTAVLDVFEFEPHVDLELLPLL-AFATPHIA 262



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>Q8FFH2:PDXB_ECOL6 Erythronate-4-phosphate dehydrogenase - Escherichia coli O6|
          Length = 378

 Score = 63.2 bits (152), Expect = 3e-09
 Identities = 52/178 (29%), Positives = 85/178 (47%), Gaps = 4/178 (2%)
 Frame = +2

Query: 647  GNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGE 826
            G  L  +TVG++G G +G    +  +E   +  +  D  ++ R ++     G F      
Sbjct: 111  GFSLHERTVGIVGVGNVGRRL-QARLEALGIKTLLCDPPRADRGDE-----GDF------ 158

Query: 827  QPVTWKRASSMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGP 994
                     S++E+++ AD+++ H  L K     T HL + + +  +K  A+L+NA RG 
Sbjct: 159  --------RSLDELVQHADILTFHTPLFKDGPYKTLHLADEKLIRSLKPGAILINACRGA 210

Query: 995  VIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA 1168
            V+D  AL+  L       V LDV+E EP +   L + K  +  PHIA    +T EG A
Sbjct: 211  VVDNTALLTCLNEGQKLSVVLDVWEGEPELNVELLK-KVDIGTPHIAG---YTLEGKA 264



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>Q83QR1:PDXB_SHIFL Erythronate-4-phosphate dehydrogenase - Shigella flexneri|
          Length = 378

 Score = 62.8 bits (151), Expect = 4e-09
 Identities = 52/178 (29%), Positives = 84/178 (47%), Gaps = 4/178 (2%)
 Frame = +2

Query: 647  GNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGE 826
            G  L  +TVG++G G +G    +  +E   +  +  D  ++ R ++     G F      
Sbjct: 111  GFSLHDRTVGIVGVGNVGRRL-QARLEALGIKTLLCDPPRADRGDE-----GDF------ 158

Query: 827  QPVTWKRASSMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGP 994
                     S++E+++ AD+++ H  L K     T HL + + +  +K  A+L+NA RG 
Sbjct: 159  --------RSLDELVQRADILTFHTPLFKDGPYKTLHLADEKLIRSLKPGAILINACRGA 210

Query: 995  VIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA 1168
            V+D  AL+  L       V LDV+E EP +   L   K  +  PHIA    +T EG A
Sbjct: 211  VVDNTALLTCLNEGQKLSVVLDVWEGEPELNVELL-TKVDIGTPHIAG---YTLEGKA 264



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>Q7VRU9:PDXB_BLOFL Erythronate-4-phosphate dehydrogenase - Blochmannia floridanus|
          Length = 372

 Score = 62.0 bits (149), Expect = 7e-09
 Identities = 49/168 (29%), Positives = 88/168 (52%), Gaps = 5/168 (2%)
 Frame = +2

Query: 656  LKGQTVGVIGAGRIGSA-YARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQP 832
            L+ +TVG+IG G IG+  Y R+   G  ++ + +D Y+S              K + ++ 
Sbjct: 114  LRDKTVGIIGVGNIGNLLYQRLNSLG--VHTLLYDPYKS--------------KCDTDR- 156

Query: 833  VTWKRASSMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVI 1000
            ++WK   S++ ++ ++D+++LH  L  T    T+H+IN + L  +   ++L+N SRG V+
Sbjct: 157  MSWK---SLDILVSKSDILTLHVPLTYTGAYPTWHMINKDILDALPSNSILINTSRGAVV 213

Query: 1001 DEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASAS 1144
            +   L+  L+      V LDV+E EP +   L    + +   HIA  S
Sbjct: 214  NNDDLLAILRCGKKINVILDVWESEPKLSLPLLSYVD-IGTAHIAGYS 260



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>P33677:FDH_PICAN Formate dehydrogenase - Pichia angusta (Yeast) (Hansenula polymorpha)|
          Length = 362

 Score = 60.8 bits (146), Expect = 2e-08
 Identities = 54/216 (25%), Positives = 97/216 (44%), Gaps = 4/216 (1%)
 Frame = +2

Query: 452  VGYNNVDVDAANKNG--IAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDG 625
            VG +++D+D  N++G  I++    G    +             R  V A + + +G   G
Sbjct: 93   VGSDHIDLDYINQSGRDISVLEVTGSNVVSVAEHVVMTMLVLVRNFVPAHEQIISG---G 149

Query: 626  WLPHLFVGNL--LKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAY 799
            W       +   ++G+ +  IGAGRIG      ++      L+Y+D YQS          
Sbjct: 150  WNVAEIAKDSFDIEGKVIATIGAGRIGYRVLERLVAFNPKELLYYD-YQS---------- 198

Query: 800  GQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVN 979
               L    E+ V  +R   ++E++ +AD+++++  L   +  L+N E L   KK A LVN
Sbjct: 199  ---LSKEAEEKVGARRVHDIKELVAQADIVTINCPLHAGSKGLVNAELLKHFKKGAWLVN 255

Query: 980  ASRGPVIDEVALVEHLKANPMFRVGLDVFEDEPYMK 1087
             +RG +     +   +K+  +   G DV+  +P  K
Sbjct: 256  TARGAICVAEDVAAAVKSGQLRGYGGDVWFPQPAPK 291



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>P05459:PDXB_ECOLI Erythronate-4-phosphate dehydrogenase - Escherichia coli|
          Length = 378

 Score = 60.1 bits (144), Expect = 3e-08
 Identities = 51/178 (28%), Positives = 84/178 (47%), Gaps = 4/178 (2%)
 Frame = +2

Query: 647  GNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGE 826
            G  L  +TVG++G G +G    +  +E   +  +  D  ++ R ++     G F      
Sbjct: 111  GFSLYDRTVGIVGVGNVGRRL-QARLEALGIKTLLCDPPRADRGDE-----GDF------ 158

Query: 827  QPVTWKRASSMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGP 994
                     S++E+++ AD+++ H  L K     T HL + + +  +K  A+L+NA RG 
Sbjct: 159  --------RSLDELVQRADILTFHTPLFKDGPYKTLHLADEKLIRSLKPGAILINACRGA 210

Query: 995  VIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA 1168
            V+D  AL+  L       V LDV+E EP +   L + K  +   HIA    +T EG A
Sbjct: 211  VVDNTALLTCLNEGQKLSVVLDVWEGEPELNVELLK-KVDIGTSHIAG---YTLEGKA 264



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>Q08987:FDH2_YEAST Formate dehydrogenase 2 - Saccharomyces cerevisiae (Baker's yeast)|
          Length = 376

 Score = 60.1 bits (144), Expect = 3e-08
 Identities = 52/214 (24%), Positives = 95/214 (44%), Gaps = 2/214 (0%)
 Frame = +2

Query: 452  VGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYD--G 625
            VG ++VD++AAN+  I +    G    +             R      Q    G +D  G
Sbjct: 97   VGSDHVDLEAANERKITVTEVTGSNVVSVAEHVMATILVLIRNYNGGHQQAINGEWDIAG 156

Query: 626  WLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQ 805
               + +    L+ + +  +GAGRIG      ++      L+Y+D YQ    E        
Sbjct: 157  VAKNEYD---LEDKIISTVGAGRIGYRVLERLVAFNPKKLLYYD-YQELPAEAINRLNEA 212

Query: 806  FLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNAS 985
                NG   +  +R   +E+++ ++DV++++  L K +  L N + ++ MK  A LVN +
Sbjct: 213  SKLFNGRGDIV-QRVEKLEDMVAQSDVVTINCPLHKDSRGLFNKKLISHMKDGAYLVNTA 271

Query: 986  RGPVIDEVALVEHLKANPMFRVGLDVFEDEPYMK 1087
            RG +     + E +K+  +   G DV++ +P  K
Sbjct: 272  RGAICVAEDVAEAVKSGKLAGYGGDVWDKQPAPK 305



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>Q08911:FDH1_YEAST Formate dehydrogenase 1 - Saccharomyces cerevisiae (Baker's yeast)|
          Length = 376

 Score = 60.1 bits (144), Expect = 3e-08
 Identities = 52/214 (24%), Positives = 95/214 (44%), Gaps = 2/214 (0%)
 Frame = +2

Query: 452  VGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYD--G 625
            VG ++VD++AAN+  I +    G    +             R      Q    G +D  G
Sbjct: 97   VGSDHVDLEAANERKITVTEVTGSNVVSVAEHVMATILVLIRNYNGGHQQAINGEWDIAG 156

Query: 626  WLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQ 805
               + +    L+ + +  +GAGRIG      ++      L+Y+D YQ    E        
Sbjct: 157  VAKNEYD---LEDKIISTVGAGRIGYRVLERLVAFNPKKLLYYD-YQELPAEAINRLNEA 212

Query: 806  FLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNAS 985
                NG   +  +R   +E+++ ++DV++++  L K +  L N + ++ MK  A LVN +
Sbjct: 213  SKLFNGRGDIV-QRVEKLEDMVAQSDVVTINCPLHKDSRGLFNKKLISHMKDGAYLVNTA 271

Query: 986  RGPVIDEVALVEHLKANPMFRVGLDVFEDEPYMK 1087
            RG +     + E +K+  +   G DV++ +P  K
Sbjct: 272  RGAICVAEDVAEAVKSGKLAGYGGDVWDKQPAPK 305



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>Q8XCR0:PDXB_ECO57 Erythronate-4-phosphate dehydrogenase - Escherichia coli O157:H7|
          Length = 378

 Score = 59.3 bits (142), Expect = 4e-08
 Identities = 39/109 (35%), Positives = 59/109 (54%), Gaps = 4/109 (3%)
 Frame = +2

Query: 854  SMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVE 1021
            S++E+++ AD+++ H  L K     T HL + + +  +K  A+L+NA RG V+D  AL+ 
Sbjct: 160  SLDELVQRADILTFHTPLFKDGPYKTLHLADEKLIRSLKPGAILINACRGAVVDNTALLT 219

Query: 1022 HLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA 1168
             L       V LDV+E EP +   L   K  +  PHIA    +T EG A
Sbjct: 220  CLNEGQKLSVVLDVWEGEPELNVELL-TKVDIGTPHIAG---YTLEGKA 264



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>Q02961:YP113_YEAST Putative 2-hydroxyacid dehydrogenase YPL113C - Saccharomyces|
            cerevisiae (Baker's yeast)
          Length = 396

 Score = 58.9 bits (141), Expect = 6e-08
 Identities = 44/155 (28%), Positives = 75/155 (48%), Gaps = 1/155 (0%)
 Frame = +2

Query: 677  VIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASS 856
            ++G G IG      + + F M++ Y+   ++  ++K +  Y     ++ + P TWK A  
Sbjct: 222  ILGFGSIGQNIGSNLHKVFNMSIEYYK--RTGPVQKSLLDYNAKYHSDLDDPNTWKNA-- 277

Query: 857  MEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKAN 1036
                    D+I L      +T ++IN + LA  K    +VN  RG  IDE  L++ L++ 
Sbjct: 278  --------DLIILALPSTASTNNIINRKSLAWCKDGVRIVNVGRGTCIDEDVLLDALESG 329

Query: 1037 PMFRVGLDVFE-DEPYMKPGLAEMKNAVVVPHIAS 1138
             +   GLDVF+ +E  +K  L    +   +PHI S
Sbjct: 330  KVASCGLDVFKNEETRVKQELLRRWDVTALPHIGS 364



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>Q83AR8:PDXB_COXBU Erythronate-4-phosphate dehydrogenase - Coxiella burnetii|
          Length = 366

 Score = 58.5 bits (140), Expect = 8e-08
 Identities = 42/97 (43%), Positives = 55/97 (56%), Gaps = 4/97 (4%)
 Frame = +2

Query: 869  LREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKAN 1036
            L   D++ LH  L KT    TYHLI+   L M+K  +VL+NA RG VID  AL   L+ +
Sbjct: 165  LANVDLVCLHTPLVKTGNFPTYHLIDNRFLKMLKPGSVLLNAGRGAVIDNNAL---LQCD 221

Query: 1037 PMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASK 1147
             +    LDV+E+EP +   L E K  +  PHIA  SK
Sbjct: 222  HVITC-LDVWENEPTVNLQLLE-KTTIATPHIAGYSK 256



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>Q7MV70:PDXB_PORGI Erythronate-4-phosphate dehydrogenase - Porphyromonas gingivalis|
            (Bacteroides gingivalis)
          Length = 377

 Score = 57.8 bits (138), Expect = 1e-07
 Identities = 60/225 (26%), Positives = 96/225 (42%), Gaps = 11/225 (4%)
 Frame = +2

Query: 647  GNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYG-QFL---- 811
            G  LK + +G++G G +G                         L++  +AYG +FL    
Sbjct: 119  GFSLKEKVMGIVGVGHVGG-----------------------ELKRLASAYGMEFLLCDP 155

Query: 812  -KANGEQPVTWKRASSMEEVLREADVISLHPVL----DKTTYHLINPERL-AMMKKEAVL 973
             ++  EQ  ++   S + E   + D+IS H  L       TYHLI    L +   K  +L
Sbjct: 156  PRSEAEQDNSFLPLSRLVE---QCDIISFHVPLTHEDPHATYHLIGEAFLRSCADKRPIL 212

Query: 974  VNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWT 1153
            +NA RG V D  AL+  +K+  +  + +D +E EP +   L ++ + +  PHIA  S   
Sbjct: 213  INACRGAVADTQALIRAVKSGWLQALVIDCWEGEPDIDLSLLDLAD-IATPHIAGFSADG 271

Query: 1154 REGMATLAALNVLGKIKGYPVWGNPNAVEPFLDEEATPPPACPSI 1288
            +   A +  L  + ++ G           P L   A PPP  P I
Sbjct: 272  KANGARM-CLEAITEVFGLEF--------PLLHTLAPPPPTHPII 307



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>P33160:FDH_PSESR Formate dehydrogenase - Pseudomonas sp. (strain 101) (Achromobacter|
            parvulus T1)
          Length = 401

 Score = 56.2 bits (134), Expect = 4e-07
 Identities = 54/214 (25%), Positives = 95/214 (44%), Gaps = 2/214 (0%)
 Frame = +2

Query: 452  VGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWL 631
            +G ++VD+ +A    + +       + +             R  + + ++ R G   GW 
Sbjct: 123  IGSDHVDLQSAIDRNVTVAEVTYCNSISVAEHVVMMILSLVRNYLPSHEWARKG---GWN 179

Query: 632  PHLFVGNL--LKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQ 805
                V +   L+   VG + AGRIG A  R +   F ++L Y D +   RL + V     
Sbjct: 180  IADCVSHAYDLEAMHVGTVAAGRIGLAVLRRLAP-FDVHLHYTDRH---RLPESVEK--- 232

Query: 806  FLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNAS 985
                  E  +TW   ++ E++    DV++L+  L   T H+IN E L + K+ A +VN +
Sbjct: 233  ------ELNLTWH--ATREDMYPVCDVVTLNCPLHPETEHMINDETLKLFKRGAYIVNTA 284

Query: 986  RGPVIDEVALVEHLKANPMFRVGLDVFEDEPYMK 1087
            RG + D  A+   L++  +     DV+  +P  K
Sbjct: 285  RGKLCDRDAVARALESGRLAGYAGDVWFPQPAPK 318



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>P53100:YGT5_YEAST Putative 2-hydroxyacid dehydrogenase YGL185C - Saccharomyces|
            cerevisiae (Baker's yeast)
          Length = 379

 Score = 49.3 bits (116), Expect = 5e-05
 Identities = 46/189 (24%), Positives = 74/189 (39%), Gaps = 6/189 (3%)
 Frame = +2

Query: 659  KGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVT 838
            +G+   ++G G IG   A  +  G  M + Y    +   +                Q  +
Sbjct: 196  RGKKCLILGLGSIGKQVAYKLQYGLGMEIHYCKRSEDCTMS---------------QNES 240

Query: 839  WKRASSMEEVLREADVISLHPVL-----DKTTYHLINPERLAMMKKEAVLVNASRGPVID 1003
            WK     E +   A +   H ++        T HLIN + L       +LVN  RG ++D
Sbjct: 241  WKFHLLDETIY--AKLYQFHAIVVTLPGTPQTEHLINRKFLEHCNPGLILVNLGRGKILD 298

Query: 1004 EVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAV-VVPHIASASKWTREGMATLAA 1180
              A+ + L    +  +GLDVF  EP +   +        + PH+ SA+K   E    LA 
Sbjct: 299  LRAVSDALVTGRINHLGLDVFNKEPEIDEKIRSSDRLTSITPHLGSATKDVFEQSCELAL 358

Query: 1181 LNVLGKIKG 1207
              +L  + G
Sbjct: 359  TRILRVVSG 367



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>Q09054:G3PD_MAIZE Glyceraldehyde-3-phosphate dehydrogenase, cytosolic 2 - Zea mays|
            (Maize)
          Length = 337

 Score = 33.9 bits (76), Expect = 2.0
 Identities = 39/163 (23%), Positives = 66/163 (40%), Gaps = 5/163 (3%)
 Frame = +2

Query: 671  VGVIGAGRIGSAYARMMIEGFKMNLI-----YFDLYQSTRLEKFVTAYGQFLKANGEQPV 835
            +G+ G GRIG   AR+ ++   + L+     +      T + K+ T +GQ          
Sbjct: 6    IGINGFGRIGRLVARVALQSEDVELVAVNDPFITTDYMTYMFKYDTVHGQ---------- 55

Query: 836  TWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVAL 1015
             WK +   +  L+++  + L      T + + NPE +   +  A  V  S G   D+   
Sbjct: 56   -WKHS---DIALKDSKTL-LFGEKPVTVFGIRNPEEIPWGEAGAEYVVESTGVFTDKDKA 110

Query: 1016 VEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASAS 1144
              HLK      V     +D P    G+ E K    V  +++AS
Sbjct: 111  AAHLKGGAKKVVISAPSKDAPMFVVGVNEDKYTSDVNIVSNAS 153



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>P75913:YCDW_ECOLI Putative 2-hydroxyacid dehydrogenase ycdW - Escherichia coli|
          Length = 325

 Score = 33.5 bits (75), Expect = 2.6
 Identities = 42/162 (25%), Positives = 70/162 (43%), Gaps = 2/162 (1%)
 Frame = +2

Query: 668  TVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKR 847
            T+G++GAG +GS  A+       +    F L   +R  K       F  A  E+      
Sbjct: 151  TIGILGAGVLGSKVAQ------SLQTWRFPLRCWSRTRKSWPGVQSF--AGREE------ 196

Query: 848  ASSMEEVLREADV-ISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEH 1024
               +   L +  V I+L P   +T   +IN + L  +   A L+N +RG  + E  L+  
Sbjct: 197  ---LSAFLSQCRVLINLLPNTPETV-GIINQQLLEKLPDGAYLLNLARGVHVVEDDLLAA 252

Query: 1025 LKANPMFRVGLDVFEDEPY-MKPGLAEMKNAVVVPHIASASK 1147
            L +  +    LDVF  EP   +  L +     + PH+A+ ++
Sbjct: 253  LDSGKVKGAMLDVFNREPLPPESPLWQHPRVTITPHVAAITR 294



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>Q0J8A4:G3PC_ORYSJ Glyceraldehyde-3-phosphate dehydrogenase, cytosolic - Oryza sativa|
            subsp. japonica (Rice)
          Length = 337

 Score = 33.1 bits (74), Expect = 3.4
 Identities = 38/163 (23%), Positives = 66/163 (40%), Gaps = 5/163 (3%)
 Frame = +2

Query: 671  VGVIGAGRIGSAYARMMIEGFKMNLI-----YFDLYQSTRLEKFVTAYGQFLKANGEQPV 835
            +G+ G GRIG   AR+ ++   + L+     +      T + K+ T +GQ          
Sbjct: 6    IGINGFGRIGRLVARVALQSEDVELVAVNDPFITTDYMTYMFKYDTVHGQ---------- 55

Query: 836  TWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVAL 1015
             WK  S ++    +  ++   PV   T + + NP+ +   +  A  V  S G   D+   
Sbjct: 56   -WKH-SDIKIKDSKTLLLGEKPV---TVFGIRNPDEIPWAEAGAEYVVESTGVFTDKEKA 110

Query: 1016 VEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASAS 1144
              HLK      V     +D P    G+ E K    +  +++AS
Sbjct: 111  AAHLKGGAKKVVISAPSKDAPMFVCGVNEDKYTSDIDIVSNAS 153



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>A2YQT7:G3PC_ORYSI Glyceraldehyde-3-phosphate dehydrogenase, cytosolic - Oryza sativa|
            subsp. indica (Rice)
          Length = 337

 Score = 33.1 bits (74), Expect = 3.4
 Identities = 38/163 (23%), Positives = 66/163 (40%), Gaps = 5/163 (3%)
 Frame = +2

Query: 671  VGVIGAGRIGSAYARMMIEGFKMNLI-----YFDLYQSTRLEKFVTAYGQFLKANGEQPV 835
            +G+ G GRIG   AR+ ++   + L+     +      T + K+ T +GQ          
Sbjct: 6    IGINGFGRIGRLVARVALQSEDVELVAVNDPFITTDYMTYMFKYDTVHGQ---------- 55

Query: 836  TWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVAL 1015
             WK  S ++    +  ++   PV   T + + NP+ +   +  A  V  S G   D+   
Sbjct: 56   -WKH-SDIKIKDSKTLLLGEKPV---TVFGIRNPDEIPWAEAGAEYVVESTGVFTDKEKA 110

Query: 1016 VEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASAS 1144
              HLK      V     +D P    G+ E K    +  +++AS
Sbjct: 111  AAHLKGGAKKVVISAPSKDAPMFVCGVNEDKYTSDIDIVSNAS 153



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>A2QW93:HSE1_ASPNG Class E vacuolar protein-sorting machinery protein hse1 -|
           Aspergillus niger
          Length = 611

 Score = 32.7 bits (73), Expect = 4.4
 Identities = 17/51 (33%), Positives = 25/51 (49%)
 Frame = +1

Query: 223 GEHQVHAWHPLDQAPH*QRLPP*DMHGEEDHPLRRRHPGSHRRSLPRCHRP 375
           G  Q HA+ P  Q+P  ++ PP     ++  P ++R P S     P  HRP
Sbjct: 428 GTEQAHAYPPTSQSPDPRQTPPAGAPYQQPQPQQQRQPSSESYQ-PVYHRP 477



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>P26517:G3PX_HORVU Glyceraldehyde-3-phosphate dehydrogenase, cytosolic - Hordeum vulgare|
            (Barley)
          Length = 337

 Score = 32.7 bits (73), Expect = 4.4
 Identities = 38/163 (23%), Positives = 63/163 (38%), Gaps = 5/163 (3%)
 Frame = +2

Query: 671  VGVIGAGRIGSAYARMMIEGFKMNLI-----YFDLYQSTRLEKFVTAYGQFLKANGEQPV 835
            +G+ G GRIG   AR+ ++   + L+     +      T + K+ T +G           
Sbjct: 6    IGINGFGRIGRLVARVALQSDDVELVAVNDPFITTEYMTYMFKYDTVHGH---------- 55

Query: 836  TWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVAL 1015
             WK +    ++  + D   L      T + + NPE +   +  A  V  S G   D+   
Sbjct: 56   -WKHS----DIKLKDDKTLLFGEKPVTVFGVRNPEEIPWGEAGADYVVESTGVFTDKDKA 110

Query: 1016 VEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASAS 1144
              HLK      V     +D P    G+ E K    V  +++AS
Sbjct: 111  AAHLKGGAKKVVISAPSKDAPMFVVGVNEDKYTSDVNIVSNAS 153



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>P26520:G3PC_PETHY Glyceraldehyde-3-phosphate dehydrogenase, cytosolic - Petunia hybrida|
            (Petunia)
          Length = 337

 Score = 32.7 bits (73), Expect = 4.4
 Identities = 40/166 (24%), Positives = 63/166 (37%), Gaps = 18/166 (10%)
 Frame = +2

Query: 671  VGVIGAGRIGSAYARMMIEGFKMNLI-----YFDLYQSTRLEKFVTAYGQFLKANGEQPV 835
            +G+ G GRIG   AR+ ++   + L+     +  +   T + K+ + +GQ          
Sbjct: 6    IGINGFGRIGRLVARVALQRDDVELVAVNDPFISVEYMTYMFKYDSVHGQ---------- 55

Query: 836  TWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVAL 1015
             WK      E+  + D   L      T + + NPE +   +  A  V  S G   D+   
Sbjct: 56   -WKH----HELKAKDDKTLLFGEKPVTVFGIRNPEEIPWGEAGADYVVESTGVFTDKDKA 110

Query: 1016 VEHLKAN-------------PMFRVGLDVFEDEPYMKPGLAEMKNA 1114
              HLK               PMF VG+    +E   K  L  + NA
Sbjct: 111  AAHLKGGAKKVIISAPSKDAPMFVVGV----NEKEYKSDLTVVSNA 152



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>Q9X2N4:DLTA_STAXY D-alanine--poly(phosphoribitol) ligase subunit 1 - Staphylococcus|
            xylosus
          Length = 487

 Score = 32.3 bits (72), Expect = 5.8
 Identities = 20/50 (40%), Positives = 29/50 (58%), Gaps = 9/50 (18%)
 Frame = +3

Query: 1458 LPVYMY-ECTHLHGVVVMNEMS--------IYSIKQEIFYQLCIYMFPRK 1580
            +PVY   + T L GVVV+N+++        I+ IKQE+   +  YM PRK
Sbjct: 412  VPVYKNNKVTQLQGVVVLNDLNDDKDEQTVIHDIKQELKQAMPEYMIPRK 461



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>P08735:G3PC_MAIZE Glyceraldehyde-3-phosphate dehydrogenase, cytosolic 1 - Zea mays|
            (Maize)
          Length = 337

 Score = 32.0 bits (71), Expect = 7.5
 Identities = 38/163 (23%), Positives = 67/163 (41%), Gaps = 5/163 (3%)
 Frame = +2

Query: 671  VGVIGAGRIGSAYARMMIEGFKMNLI-----YFDLYQSTRLEKFVTAYGQFLKANGEQPV 835
            +G+ G GRIG   AR+ ++   + L+     +      T + K+ T +G +  ++    +
Sbjct: 6    IGINGFGRIGRLVARVALQSEDVELVAVNDPFITTDYMTYMFKYDTVHGHWKHSD----I 61

Query: 836  TWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVAL 1015
            T K + ++        +    PV   T + + NPE +   +  A  V  S G   D+   
Sbjct: 62   TLKDSKTL--------LFGDKPV---TVFGIRNPEEIPWGEAGAEYVVESTGVFTDKDKA 110

Query: 1016 VEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASAS 1144
              HLK      V     +D P    G+ E K    V  +++AS
Sbjct: 111  AAHLKGGAKKVVISAPSKDAPMFVVGVNEDKYTSDVNIVSNAS 153



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>O51934:RGYR_THEMA Reverse gyrase [Includes: Helicase - Thermotoga maritima|
          Length = 1104

 Score = 31.6 bits (70), Expect = 9.8
 Identities = 19/67 (28%), Positives = 34/67 (50%)
 Frame = +2

Query: 683  GAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSME 862
            G GR  S YA+++   F+   +Y D Y+  R  +F      +LK   E+ VT +    +E
Sbjct: 1015 GIGR-PSTYAKIVEVLFRRGYVYEDKYKRVRPTRFGVMVYSYLKERYEKYVTEETTRRLE 1073

Query: 863  EVLREAD 883
            E++ + +
Sbjct: 1074 EIMDKVE 1080



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>Q9GKQ1:HSP1_SAISC Sperm protamine-P1 - Saimiri sciureus (Common squirrel monkey)|
          Length = 50

 Score = 31.6 bits (70), Expect = 9.8
 Identities = 17/37 (45%), Positives = 20/37 (54%)
 Frame = -1

Query: 512 CCRWRCRSCWQHRRQRCCTRQPYC*RLSHQRA*GQRR 402
           CCR R RS    RR+RC TR+  C R    R   +RR
Sbjct: 6   CCRSRSRSRCYRRRRRCRTRRRRCCRRRRARRCCRRR 42



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>P33450:FAT_DROME Cadherin-related tumor suppressor precursor - Drosophila melanogaster|
            (Fruit fly)
          Length = 5147

 Score = 31.6 bits (70), Expect = 9.8
 Identities = 18/65 (27%), Positives = 33/65 (50%)
 Frame = +2

Query: 755  DLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLIN 934
            ++  +T L++  T+         +  +T  RASS+   +  +DV    P  D TTY++  
Sbjct: 2546 EISTATTLDREETSVYHLTLMAQDSSITEPRASSVNLTISVSDVNDNIPKFDSTTYNVAV 2605

Query: 935  PERLA 949
            PER++
Sbjct: 2606 PERIS 2610



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>Q8TGE1:AWA1_YEAST Cell wall protein AWA1 precursor - Saccharomyces cerevisiae (Baker's|
            yeast)
          Length = 1713

 Score = 31.6 bits (70), Expect = 9.8
 Identities = 35/120 (29%), Positives = 54/120 (45%), Gaps = 8/120 (6%)
 Frame = -3

Query: 1296 ALTMLGQAGGGVASSS-----RKGSTAFGFPHTGYPLILPSTFRAASVAIPSRVHLDADA 1132
            ++T  G A G  ASS+     + GS+  G   +  P I  S  ++ S A  +   + +  
Sbjct: 691  SITQSGTASGSSASSTSGSVTQSGSSVSGSSASSAPGISSSIPQSTSSASTASGSITS-- 748

Query: 1131 M*GTTTAFFISASPGFM*GSSSKTSRPTRNMGLALRCSTSAT---SSITGPRLAFTSTAS 961
              GT T+    +S     GSS+  S      G ++  STSAT   SS++G   A  S +S
Sbjct: 749  --GTLTSITSGSSSATESGSSASGSSSATESGSSVSGSTSATESGSSVSGSTSATESGSS 806


  Database: uniprot_sprot.fasta.out
    Posted date:  Jul 19, 2007  5:58 PM
  Number of letters in database: 100,686,439
  Number of sequences in database:  274,295
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 274295
Number of Hits to DB: 261,456,309
Number of extensions: 5602805
Number of successful extensions: 18165
Number of sequences better than 10.0: 131
Number of HSP's gapped: 17941
Number of HSP's successfully gapped: 132
Length of query: 531
Length of database: 100,686,439
Length adjustment: 118
Effective length of query: 413
Effective length of database: 68,319,629
Effective search space: 28216006777
Effective search space used: 28216006777
Neighboring words threshold: 12
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
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