ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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更新日:2016年5月1日

Clone Information

BLAST Search Result

Clone Name FLbaf95g16
Clone Library Name barley_pub

No. Definition Score
(bits)
E
Value
1P55217:METB_ARATH Cystathionine gamma-synthase, chloroplast prec... 633 0.0
2P56069:METB_HELPY Cystathionine gamma-synthase - Helicobacter py... 272 3e-72
3A2RM21:METC_LACLM Cystathionine beta-lyase - Lactococcus lactis ... 262 3e-69
4P0A4K2:METC_LACLA Cystathionine beta-lyase - Lactococcus lactis ... 262 3e-69
5Q9ZMW7:METB_HELPJ Cystathionine gamma-synthase - Helicobacter py... 261 5e-69
6P55218:METZ_PSEAE O-succinylhomoserine sulfhydrylase - Pseudomon... 260 2e-68
7Q19QT7:CGL_PIG Cystathionine gamma-lyase - Sus scrofa (Pig) 255 5e-67
8P0C2T9:METC_LACLC Cystathionine beta-lyase - Lactococcus lactis ... 254 8e-67
9Q60HG7:CGL_MACFA Cystathionine gamma-lyase - Macaca fascicularis... 251 5e-66
10P66875:METB_MYCTU Cystathionine gamma-synthase - Mycobacterium t... 245 5e-64
11P66876:METB_MYCBO Cystathionine gamma-synthase - Mycobacterium b... 245 5e-64
12Q58DW2:CGL_BOVIN Cystathionine gamma-lyase - Bos taurus (Bovine) 244 1e-63
13P32929:CGL_HUMAN Cystathionine gamma-lyase - Homo sapiens (Human) 243 1e-63
14P46807:METB_MYCLE Cystathionine gamma-synthase - Mycobacterium l... 239 3e-62
15P13254:MEGL_PSEPU Methionine gamma-lyase - Pseudomonas putida 234 7e-61
16P55216:CGL_CAEEL Putative cystathionine gamma-lyase - Caenorhabd... 234 9e-61
17P24601:METB_HERAU Probable cystathionine gamma-synthase - Herpet... 231 8e-60
18Q8VCN5:CGL_MOUSE Cystathionine gamma-lyase - Mus musculus (Mouse) 229 4e-59
19P53780:METC_ARATH Cystathionine beta-lyase, chloroplast precurso... 228 8e-59
20P18757:CGL_RAT Cystathionine gamma-lyase - Rattus norvegicus (Rat) 224 1e-57
21P31373:CYS3_YEAST Cystathionine gamma-lyase - Saccharomyces cere... 210 1e-53
22P44502:METB_HAEIN Cystathionine gamma-synthase - Haemophilus inf... 197 9e-50
23P00935:METB_ECOLI Cystathionine gamma-synthase - Escherichia coli 197 1e-49
24O13326:CYSD_SCHPO O-acetylhomoserine - Schizosaccharomyces pombe... 191 7e-48
25Q52811:METC_RHIL3 Putative cystathionine beta-lyase - Rhizobium ... 190 1e-47
26Q59829:CYSA_STRCO Putative cystathionine gamma-lyase - Streptomy... 183 2e-45
27P50125:CYSD_EMENI O-acetylhomoserine - Emericella nidulans (Aspe... 172 3e-42
28P06106:MET17_YEAST Protein MET17 [Includes: O-acetylhomoserine s... 167 1e-40
29Q92441:MET17_KLULA Protein MET17 [Includes: O-acetylhomoserine s... 159 3e-38
30P53101:STR3_YEAST Cystathionine beta-lyase - Saccharomyces cerev... 148 8e-35
31Q07703:METC_BORAV Cystathionine beta-lyase - Bordetella avium 143 2e-33
32P06721:METC_ECOLI Cystathionine beta-lyase - Escherichia coli 140 2e-32
33P44527:METC_HAEIN Cystathionine beta-lyase - Haemophilus influenzae 140 2e-32
34P18949:METC_SALTY Cystathionine beta-lyase - Salmonella typhimurium 129 4e-29
35P38716:YHR2_YEAST Uncharacterized trans-sulfuration enzyme YHR11... 127 2e-28
36O42851:YFHE_SCHPO Uncharacterized trans-sulfuration enzyme C23A1... 124 1e-27
37P43623:METC_YEAST Putative cystathionine beta-lyase - Saccharomy... 114 1e-24
38O74314:MET7_SCHPO Probable cystathionine gamma-synthase - Schizo... 90 3e-17
39P38675:MET7_NEUCR Cystathionine gamma-synthase - Neurospora crassa 85 1e-15
40P47164:MET7_YEAST Cystathionine gamma-synthase - Saccharomyces c... 71 2e-11
41Q04533:METX_YEAST Putative cystathionine gamma-synthase YML082W ... 69 6e-11
42Q12198:METW_YEAST Putative cystathionine gamma-synthase YLL058W ... 65 7e-10
43Q57622:Y158_METJA UPF0425 pyridoxal phosphate-dependent protein ... 42 0.006
44O27936:Y1914_METTH UPF0425 pyridoxal phosphate-dependent protein... 35 1.3
45Q818M4:GCSPA_BACCR Probable glycine dehydrogenase [decarboxylati... 34 2.3
46Q9HPK0:GCSPB_HALSA Probable glycine dehydrogenase [decarboxylati... 33 3.0
47P25070:TCH2_ARATH Calmodulin-related protein 2, touch-induced - ... 33 3.9
48Q7TQM5:KPRP_RAT Keratinocyte proline-rich protein - Rattus norve... 33 5.1
49O67140:SELA_AQUAE L-seryl-tRNA(Sec) selenium transferase - Aquif... 32 6.7
50Q82WM3:HIS81_NITEU Histidinol-phosphate aminotransferase 1 - Nit... 32 8.7

>P55217:METB_ARATH Cystathionine gamma-synthase, chloroplast precursor - Arabidopsis|
            thaliana (Mouse-ear cress)
          Length = 563
 Score =  633 bits (1632), Expect = 0.0
 Identities = 326/506 (64%), Positives = 378/506 (74%), Gaps = 20/506 (3%)
 Frame = +1

Query: 145  SATILRFPPNFVRQLSTKARRNCSNIGVAQIVAAAWSDR--SAVPSPFGGGSRVRGXXXX 318
            S+ ILRFPPNFVRQLS KARRNCSNIGVAQIVAA WS+   SA+PS     +        
Sbjct: 58   SSRILRFPPNFVRQLSIKARRNCSNIGVAQIVAAKWSNNPSSALPSAAAAAATSSASAVS 117

Query: 319  XXXXXXXXXXXXXXEVGAIPNAKLAQPSAATL-----------------AERALLGSDAS 447
                           V A P   L       +                 ++ + L SD S
Sbjct: 118  SAASAAAASSAAAAPVAAAPPVVLKSVDEEVVVAEEGIREKIGSVQLTDSKHSFLSSDGS 177

Query: 448  LAVHAGERLGRRIATDAITTPVVNTSAYWFSSSQELIDFKEGRHASFEYGRYGNPTTEAL 627
            L VHAGERLGR I TDAITTPVVNTSAY+F  + ELIDFKE R  SFEYGRYGNPTT  L
Sbjct: 178  LTVHAGERLGRGIVTDAITTPVVNTSAYFFKKTAELIDFKEKRSVSFEYGRYGNPTTVVL 237

Query: 628  EKKMSALEKAESTVFVASGMYASVAMLSTLVPAGGHIVTTTDLYRKTRIYMETELPKRGI 807
            E K+SALE AEST+ +ASGM AS  ML  LVPAGGHIVTTTD YRKTRI+ME  LPK GI
Sbjct: 238  EDKISALEGAESTLVMASGMCASTVMLLALVPAGGHIVTTTDCYRKTRIFMENFLPKLGI 297

Query: 808  TMTVIRPADMDALQDALDNNNVSLFFTETPTNPFLRCIDIELVSNMCHNKGALLCIDSTF 987
            T+TVI PAD+  L+ A++   VSLFFTE+PTNPFLRC+DIELVS +CH +G L+CID TF
Sbjct: 298  TVTVIDPADIAGLEAAVNEFKVSLFFTESPTNPFLRCVDIELVSKICHKRGTLVCIDGTF 357

Query: 988  ASPINQKALTLGADIVVHSATKYIAGHNDVIGGCISGRGELVSKVRIYHHVVGGVLNPNA 1167
            A+P+NQKAL LGAD+VVHSATKYI GHNDV+ GCI G  +LVS++R  HHV+GG LNPNA
Sbjct: 358  ATPLNQKALALGADLVVHSATKYIGGHNDVLAGCICGSLKLVSEIRNLHHVLGGTLNPNA 417

Query: 1168 SYLILRGMKTLHLRVQCQNNTALRMAQFLEEHPKIARVYYPGLPSHPEHHIAKSQMTGFG 1347
            +YLI+RGMKTLHLRVQ QN+TA RMA+ LE HPK++ VYYPGLPSHPEH +AK QMTGFG
Sbjct: 418  AYLIIRGMKTLHLRVQQQNSTAFRMAEILEAHPKVSHVYYPGLPSHPEHELAKRQMTGFG 477

Query: 1348 GVVSFEVDGDFDSTRRFIDSVKIPYHAPSFGGCESIIDQPAIMSYWD-SKEQRDIYGIKD 1524
            GVVSFE+DGD ++T +F+DS+KIPY APSFGGCESI+DQPAIMSYWD  +E+R  YGIKD
Sbjct: 478  GVVSFEIDGDIETTIKFVDSLKIPYIAPSFGGCESIVDQPAIMSYWDLPQEERLKYGIKD 537

Query: 1525 NLIRFSIGVEDFGDLKNDIVQALDKI 1602
            NL+RFS GVEDF D+K DI+QAL+ I
Sbjct: 538  NLVRFSFGVEDFEDVKADILQALEAI 563



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>P56069:METB_HELPY Cystathionine gamma-synthase - Helicobacter pylori (Campylobacter|
            pylori)
          Length = 380

 Score =  272 bits (696), Expect = 3e-72
 Identities = 150/385 (38%), Positives = 230/385 (59%), Gaps = 2/385 (0%)
 Frame = +1

Query: 454  VHAGERLGRRIATDAITTPVVNTSAYWFSSSQELIDFKEGRHASFEYGRYGNPTTEALEK 633
            +H G  +     T A++ P+  TS Y     Q+ I    GRH  +EY R GNPT  ALE+
Sbjct: 8    IHGG--ISEDATTGAVSVPIYQTSTY----RQDAI----GRHKGYEYSRSGNPTRFALEE 57

Query: 634  KMSALEKAESTVFVASGMYASVAMLSTLVPAGGHIVTTTDLYRKTRIYMETELPKRGITM 813
             ++ LE        ASG+ A +  + +L+ +G H++   D+Y  T       L K G++ 
Sbjct: 58   LIADLEGGVKGFAFASGL-AGIHAVFSLLQSGDHVLLGDDVYGGTFRLFNQVLVKNGLSC 116

Query: 814  TVIRPADMDALQDALDNNNVSLFFTETPTNPFLRCIDIELVSNMCHNKGALLCIDSTFAS 993
            T+I  +D+  ++ A+  N  +L+  ETP+NP L+  D+   +++  + G L  +D+TFA+
Sbjct: 117  TIIDTSDISQIKKAIKPNTKALYL-ETPSNPLLKITDLAQCASVAKDHGLLTIVDNTFAT 175

Query: 994  PINQKALTLGADIVVHSATKYIAGHNDVIGGCISGRGE-LVSKVRIYHHVVGGVLNPNAS 1170
            P  Q  L LGADIV HS TKY+ GH+DV+ G ++   E L  ++  + + +GGVL P  S
Sbjct: 176  PYYQNPLLLGADIVAHSGTKYLGGHSDVVAGLVTTNNEALAQEIAFFQNAIGGVLGPQDS 235

Query: 1171 YLILRGMKTLHLRVQCQNNTALRMAQFLEEHPKIARVYYPGLPSHPEHHIAKSQMTGFGG 1350
            +L+ RG+KTL LR++     AL +A+FLE+HPK+ RVYYPGLP+HP + +AK QM GF G
Sbjct: 236  WLLQRGIKTLGLRMEAHQKNALCVAEFLEKHPKVERVYYPGLPTHPNYELAKKQMRGFSG 295

Query: 1351 VVSFEVDGDFDSTRRFIDSVKIPYHAPSFGGCESIIDQPAIMSY-WDSKEQRDIYGIKDN 1527
            ++SF +  D ++   F++S+K+     S GG ES++  PA M++    K QR+  GI+D 
Sbjct: 296  MLSFTLKNDSEAV-AFVESLKLFILGESLGGVESLVGIPAFMTHACIPKTQREAAGIRDG 354

Query: 1528 LIRFSIGVEDFGDLKNDIVQALDKI 1602
            L+R S+G+E   DL  D+ QA  KI
Sbjct: 355  LVRLSVGIEHEQDLLEDLEQAFAKI 379



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>A2RM21:METC_LACLM Cystathionine beta-lyase - Lactococcus lactis subsp. cremoris (strain|
            MG1363)
          Length = 380

 Score =  262 bits (670), Expect = 3e-69
 Identities = 150/372 (40%), Positives = 227/372 (61%), Gaps = 2/372 (0%)
 Frame = +1

Query: 490  TDAITTPVVNTSAYWFSSSQELIDFKEGRHASFEYGRYGNPTTEALEKKMSALEKAESTV 669
            T A++ P+  TS Y  +          G+   +EY R GNPT  ALE+ ++ LE      
Sbjct: 19   TGAVSVPIYQTSTYKQNGL--------GQPKEYEYSRSGNPTRHALEELIADLEGGVQGF 70

Query: 670  FVASGMYASVAMLSTLVPAGGHIVTTTDLYRKTRIYMETELPKRGITMTVIRPADMDALQ 849
              +SG+    A+LS L  AG HI+   D+Y  T   M+  L K GI   ++  +++D L+
Sbjct: 71   AFSSGLAGIHAVLS-LFSAGDHIILADDVYGGTFRLMDKVLTKTGIIYDLVDLSNLDDLK 129

Query: 850  DALDNNNVSLFFTETPTNPFLRCIDIELVSNMCHNKGALLCIDSTFASPINQKALTLGAD 1029
             A      +++F ETP+NP L+ +DI+ +S +     AL  +D+TFA+P  Q+ + LGAD
Sbjct: 130  AAFKEETKAIYF-ETPSNPLLKVLDIKEISAIAKAHDALTLVDNTFATPYLQQPIALGAD 188

Query: 1030 IVVHSATKYIAGHNDVIGGCISGRG-ELVSKVRIYHHVVGGVLNPNASYLILRGMKTLHL 1206
            IV+HSATKY+ GH+DV+ G ++    EL S++    + +G VL P  S+L+ RG+KTL L
Sbjct: 189  IVLHSATKYLGGHSDVVAGLVTTNSKELASEIGFLQNSIGAVLGPQDSWLVQRGIKTLAL 248

Query: 1207 RVQCQNNTALRMAQFLEEHPKIARVYYPGLPSHPEHHIAKSQMTGFGGVVSFEVDGDFDS 1386
            R++  +  A ++A+FLE    +++VYYPGL SHP H IAK QM+ FGG++SFE+  D ++
Sbjct: 249  RMEAHSANAQKIAEFLETSKAVSKVYYPGLNSHPGHEIAKKQMSAFGGMISFELT-DENA 307

Query: 1387 TRRFIDSVKIPYHAPSFGGCESIIDQPAIMSYWD-SKEQRDIYGIKDNLIRFSIGVEDFG 1563
             + F++++     A S GG ES+I+ PA+M++    KE R+  GIKD LIR S+GVE   
Sbjct: 308  VKDFVENLSYFTLAESLGGVESLIEVPAVMTHASIPKELREEIGIKDGLIRLSVGVEAIE 367

Query: 1564 DLKNDIVQALDK 1599
            DL  DI +AL+K
Sbjct: 368  DLLTDIKEALEK 379



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>P0A4K2:METC_LACLA Cystathionine beta-lyase - Lactococcus lactis subsp. lactis|
            (Streptococcus lactis)
          Length = 380

 Score =  262 bits (670), Expect = 3e-69
 Identities = 150/372 (40%), Positives = 227/372 (61%), Gaps = 2/372 (0%)
 Frame = +1

Query: 490  TDAITTPVVNTSAYWFSSSQELIDFKEGRHASFEYGRYGNPTTEALEKKMSALEKAESTV 669
            T A++ P+  TS Y  +          G+   +EY R GNPT  ALE+ ++ LE      
Sbjct: 19   TGAVSVPIYQTSTYKQNGL--------GQPKEYEYSRSGNPTRHALEELIADLEGGVQGF 70

Query: 670  FVASGMYASVAMLSTLVPAGGHIVTTTDLYRKTRIYMETELPKRGITMTVIRPADMDALQ 849
              +SG+    A+LS L  AG HI+   D+Y  T   M+  L K GI   ++  +++D L+
Sbjct: 71   AFSSGLAGIHAVLS-LFSAGDHIILADDVYGGTFRLMDKVLTKTGIIYDLVDLSNLDDLK 129

Query: 850  DALDNNNVSLFFTETPTNPFLRCIDIELVSNMCHNKGALLCIDSTFASPINQKALTLGAD 1029
             A      +++F ETP+NP L+ +DI+ +S +     AL  +D+TFA+P  Q+ + LGAD
Sbjct: 130  AAFKEETKAIYF-ETPSNPLLKVLDIKEISAIAKAHDALTLVDNTFATPYLQQPIALGAD 188

Query: 1030 IVVHSATKYIAGHNDVIGGCISGRG-ELVSKVRIYHHVVGGVLNPNASYLILRGMKTLHL 1206
            IV+HSATKY+ GH+DV+ G ++    EL S++    + +G VL P  S+L+ RG+KTL L
Sbjct: 189  IVLHSATKYLGGHSDVVAGLVTTNSKELASEIGFLQNSIGAVLGPQDSWLVQRGIKTLAL 248

Query: 1207 RVQCQNNTALRMAQFLEEHPKIARVYYPGLPSHPEHHIAKSQMTGFGGVVSFEVDGDFDS 1386
            R++  +  A ++A+FLE    +++VYYPGL SHP H IAK QM+ FGG++SFE+  D ++
Sbjct: 249  RMEAHSANAQKIAEFLETSKAVSKVYYPGLNSHPGHEIAKKQMSAFGGMISFELT-DENA 307

Query: 1387 TRRFIDSVKIPYHAPSFGGCESIIDQPAIMSYWD-SKEQRDIYGIKDNLIRFSIGVEDFG 1563
             + F++++     A S GG ES+I+ PA+M++    KE R+  GIKD LIR S+GVE   
Sbjct: 308  VKDFVENLSYFTLAESLGGVESLIEVPAVMTHASIPKELREEIGIKDGLIRLSVGVEAIE 367

Query: 1564 DLKNDIVQALDK 1599
            DL  DI +AL+K
Sbjct: 368  DLLTDIKEALEK 379



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>Q9ZMW7:METB_HELPJ Cystathionine gamma-synthase - Helicobacter pylori J99 (Campylobacter|
            pylori J99)
          Length = 380

 Score =  261 bits (668), Expect = 5e-69
 Identities = 146/385 (37%), Positives = 225/385 (58%), Gaps = 2/385 (0%)
 Frame = +1

Query: 454  VHAGERLGRRIATDAITTPVVNTSAYWFSSSQELIDFKEGRHASFEYGRYGNPTTEALEK 633
            +H G  +     T A++ P+  TS Y     Q+ I    GRH  +EY R GNPT  ALE+
Sbjct: 8    IHGG--INEDATTGAVSVPIYQTSTY----RQDAI----GRHKGYEYSRSGNPTRFALEE 57

Query: 634  KMSALEKAESTVFVASGMYASVAMLSTLVPAGGHIVTTTDLYRKTRIYMETELPKRGITM 813
             ++ LE        ASG+ A +  + +L+ +G H++   D+Y          L K G++ 
Sbjct: 58   LIADLEGGVKGFAFASGL-AGIHAVFSLLQSGDHVLLGDDVYGGNFRLFNKVLVKNGLSC 116

Query: 814  TVIRPADMDALQDALDNNNVSLFFTETPTNPFLRCIDIELVSNMCHNKGALLCIDSTFAS 993
            T+I  +D+  ++ A+  N  +L+  ETP+NP L+  D+   +++      L  +D+TFA+
Sbjct: 117  TIIDTSDLSQIKKAIKPNTKALYL-ETPSNPLLKITDLAQCASVAKEHNLLTIVDNTFAT 175

Query: 994  PINQKALTLGADIVVHSATKYIAGHNDVIGGCISGRGE-LVSKVRIYHHVVGGVLNPNAS 1170
            P  Q  L LG DIV H+ TKY+ GH+DV+ G ++   E L  +   + + +GGVL    S
Sbjct: 176  PYCQNPLLLGTDIVAHNGTKYLGGHSDVVAGLVTTNNEALAQEFDFFQNAIGGVLGLQDS 235

Query: 1171 YLILRGMKTLHLRVQCQNNTALRMAQFLEEHPKIARVYYPGLPSHPEHHIAKSQMTGFGG 1350
            +L+ RG+KTL LR++     AL +A+FLE+HPK+ RVYYPGLP+HP H +AK+QM GF G
Sbjct: 236  WLLQRGIKTLGLRMEAHQKNALCVAEFLEKHPKVERVYYPGLPTHPNHELAKAQMRGFSG 295

Query: 1351 VVSFEVDGDFDSTRRFIDSVKIPYHAPSFGGCESIIDQPAIMSY-WDSKEQRDIYGIKDN 1527
            + SF +  D ++   F++S+K+     S GG ES++  PA+M++    K QR+  GI+D 
Sbjct: 296  MFSFTLKNDSEAV-AFVESLKLFILGESLGGVESLVGIPALMTHACIPKAQREAAGIRDG 354

Query: 1528 LIRFSIGVEDFGDLKNDIVQALDKI 1602
            L+R S+G+E   DL  D+ QA  KI
Sbjct: 355  LVRLSVGIEHEQDLLEDLDQAFAKI 379



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>P55218:METZ_PSEAE O-succinylhomoserine sulfhydrylase - Pseudomonas aeruginosa|
          Length = 403

 Score =  260 bits (664), Expect = 2e-68
 Identities = 147/384 (38%), Positives = 224/384 (58%), Gaps = 1/384 (0%)
 Frame = +1

Query: 445  SLAVHAGERLGRRIATDAITTPVVNTSAYWFSSSQELIDFKEGRHASFEYGRYGNPTTEA 624
            +LAV AG+R   R         +  TS+Y F ++ +      G      Y RY NPT   
Sbjct: 21   TLAVRAGQR---RTPEGEHGEALFTTSSYVFRTAADAAARFAGEVPGNVYSRYTNPTVRT 77

Query: 625  LEKKMSALEKAESTVFVASGMYASVAMLSTLVPAGGHIVTTTDLYRKTRIYMETELPKRG 804
             E++++ALE AE  V  ASGM A +A++ +L  +G H++ +  ++  T    +    + G
Sbjct: 78   FEERIAALEGAEQAVATASGMSAILALVMSLCSSGDHVLVSRSVFGSTISLFDKYFKRFG 137

Query: 805  ITMTVIRPADMDALQDALDNNNVSLFFTETPTNPFLRCIDIELVSNMCHNKGALLCIDST 984
            I +     +D+ A + A    N  LFF E+P+NP    +DI  ++ + H KGALL +D+ 
Sbjct: 138  IQVDYPPLSDLAAWEAAC-KPNTKLFFVESPSNPLAELVDIAALAEIAHAKGALLAVDNC 196

Query: 985  FASPINQKALTLGADIVVHSATKYIAGHNDVIGGCISGRGELVSKVRIYHHVVGGVLNPN 1164
            F +P  Q+ L LGAD+V+HSATKYI G    +GG ++GRGE + +V  +    G  L+P 
Sbjct: 197  FCTPALQQPLKLGADVVIHSATKYIDGQGRGMGGVVAGRGEQMKEVVGFLRTAGPTLSPF 256

Query: 1165 ASYLILRGMKTLHLRVQCQNNTALRMAQFLEEHPKIARVYYPGLPSHPEHHIAKSQMTGF 1344
             ++L L+G++TL +R+Q  + +AL +A++LE  P I RVYY GLPSHP+H +A+ Q +GF
Sbjct: 257  NAWLFLKGLETLRIRMQAHSASALALAEWLERQPGIERVYYAGLPSHPQHELARRQQSGF 316

Query: 1345 GGVVSFEVDGDFDSTRRFIDSVKIPYHAPSFGGCESIIDQPAIMSYWD-SKEQRDIYGIK 1521
            G VVSF+V G  D+  RFID+ ++     + G  ++ I  PA  S+   S E R   GI 
Sbjct: 317  GAVVSFDVKGGRDAAWRFIDATRMVSITTNLGDTKTTIAHPATTSHGRLSPEDRARAGIG 376

Query: 1522 DNLIRFSIGVEDFGDLKNDIVQAL 1593
            D+LIR ++G+ED  DLK D+ + L
Sbjct: 377  DSLIRVAVGLEDLDDLKADMARGL 400



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>Q19QT7:CGL_PIG Cystathionine gamma-lyase - Sus scrofa (Pig)|
          Length = 405

 Score =  255 bits (651), Expect = 5e-67
 Identities = 150/387 (38%), Positives = 230/387 (59%), Gaps = 3/387 (0%)
 Frame = +1

Query: 442  ASLAVHAGERLGRRIATDAITTPVVNTSAYWFSSSQELIDFKEGRHASFEYGRYGNPTTE 621
            A+ A+HAG+    + A+ A+  P+  ++ +     QE      G+H+ FEY R GNPT  
Sbjct: 19   ATQAIHAGQE-PEQWASKAVVPPISLSTTF----KQEA----PGQHSGFEYSRSGNPTXN 69

Query: 622  ALEKKMSALEKAESTVFVASGMYASVAMLSTLVPAGGHIVTTTDLYRKTRIYMETELPKR 801
             LEK ++ L+ A+ ++  ASG+ A+V  ++ L+ AG  I++  D+Y  T  Y      + 
Sbjct: 70   CLEKAVAVLDGAKYSLAFASGLAATVT-ITHLLKAGXQIISMDDVYGGTNRYFRQVAAEF 128

Query: 802  GITMTVIRPADMDALQDALDNNNVSLFFTETPTNPFLRCIDIELVSNMCHNKG-ALLCID 978
            G+ ++ +  +    L+ A+      L + ETPTNP L+ IDIE  + + H  G  +L +D
Sbjct: 129  GLKISFVDCSKSKLLEAAI-TPETKLVWIETPTNPILKMIDIEACAQIVHKHGDIILVVD 187

Query: 979  STFASPINQKALTLGADIVVHSATKYIAGHNDVIGGCISGRGE-LVSKVRIYHHVVGGVL 1155
            +TF S   Q+ L LGADI ++SATKY+ GH+DV+ G +S   E L S++R   + +G V 
Sbjct: 188  NTFMSAYFQRPLALGADICMYSATKYMNGHSDVVMGLVSLNSETLHSRLRFLQNSLGAVP 247

Query: 1156 NPNASYLILRGMKTLHLRVQCQNNTALRMAQFLEEHPKIARVYYPGLPSHPEHHIAKSQM 1335
            +P   YL  RG+KTL +R++      + +AQFLE HP + +V YPGLPSHP+H +AK Q 
Sbjct: 248  SPIDCYLCNRGLKTLQVRMEKHFENGMAVAQFLESHPLVEKVIYPGLPSHPQHELAKRQC 307

Query: 1336 TGFGGVVSFEVDGDFDSTRRFIDSVKIPYHAPSFGGCESIIDQPAIMSYWD-SKEQRDIY 1512
            TG  G++SF + G       F+ S+K+   A S GG ES+ + PAIM++    K  R++ 
Sbjct: 308  TGCPGMISFYIKGSLHHAETFLKSLKLFTLAESLGGYESLAELPAIMTHSSVPKSDREVL 367

Query: 1513 GIKDNLIRFSIGVEDFGDLKNDIVQAL 1593
            GI+D LIR S+G+ED  DL +D+ QAL
Sbjct: 368  GIRDTLIRLSVGLEDKQDLMDDLDQAL 394



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>P0C2T9:METC_LACLC Cystathionine beta-lyase - Lactococcus lactis subsp. cremoris|
            (Streptococcus cremoris)
          Length = 380

 Score =  254 bits (649), Expect = 8e-67
 Identities = 147/384 (38%), Positives = 230/384 (59%), Gaps = 2/384 (0%)
 Frame = +1

Query: 454  VHAGERLGRRIATDAITTPVVNTSAYWFSSSQELIDFKEGRHASFEYGRYGNPTTEALEK 633
            +H G    R   T A++ P+  TS Y  +          G+   +EY R GNPT  ALE+
Sbjct: 9    IHGGISTDR--TTGAVSVPIYQTSTYKQNGL--------GQPKEYEYSRSGNPTRHALEE 58

Query: 634  KMSALEKAESTVFVASGMYASVAMLSTLVPAGGHIVTTTDLYRKTRIYMETELPKRGITM 813
             ++ LE        +SG+    A+LS L  AG HI+   D+Y  T   ++  L K GI  
Sbjct: 59   LIADLEGGVQGFAFSSGLAGIHAVLS-LFSAGDHIILADDVYGGTFRLVDKVLTKTGIIY 117

Query: 814  TVIRPADMDALQDALDNNNVSLFFTETPTNPFLRCIDIELVSNMCHNKGALLCIDSTFAS 993
             ++  ++++ L+ A      +++F ETP+NP L+ +DI+ +S++     AL  +D+TFA+
Sbjct: 118  DLVDLSNLEDLKAAFKAETKAVYF-ETPSNPLLKVLDIKEISSIAKAHNALTLVDNTFAT 176

Query: 994  PINQKALTLGADIVVHSATKYIAGHNDVIGGCIS-GRGELVSKVRIYHHVVGGVLNPNAS 1170
            P  Q+ + LGADIV+HSATKY+ GH+DV+ G ++    EL  ++    + +G VL P  S
Sbjct: 177  PYLQQPIALGADIVLHSATKYLGGHSDVVAGLVTTNSNELAIEIGFLQNSIGAVLGPQDS 236

Query: 1171 YLILRGMKTLHLRVQCQNNTALRMAQFLEEHPKIARVYYPGLPSHPEHHIAKSQMTGFGG 1350
            +L+ RG+KTL  R++  +  A ++A+FLE    +++VYYPGL +H  H IAK QMT FGG
Sbjct: 237  WLVQRGIKTLAPRMEAHSANAQKIAEFLEASQAVSKVYYPGLVNHEGHEIAKKQMTAFGG 296

Query: 1351 VVSFEVDGDFDSTRRFIDSVKIPYHAPSFGGCESIIDQPAIMSYWD-SKEQRDIYGIKDN 1527
            ++SFE+  D ++ + F+++++    A S GG ES+I+ PA+M++    KE R+  GIKD 
Sbjct: 297  MISFELT-DENAVKNFVENLRYFTLAESLGGVESLIEVPAVMTHASIPKELREEIGIKDG 355

Query: 1528 LIRFSIGVEDFGDLKNDIVQALDK 1599
            LIR S+GVE   DL  D+ +AL+K
Sbjct: 356  LIRLSVGVEALEDLLTDLKEALEK 379



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>Q60HG7:CGL_MACFA Cystathionine gamma-lyase - Macaca fascicularis (Crab eating macaque)|
            (Cynomolgus monkey)
          Length = 405

 Score =  251 bits (642), Expect = 5e-66
 Identities = 147/387 (37%), Positives = 229/387 (59%), Gaps = 3/387 (0%)
 Frame = +1

Query: 442  ASLAVHAGERLGRRIATDAITTPVVNTSAYWFSSSQELIDFKEGRHASFEYGRYGNPTTE 621
            A+ A+H G+   +   T     P+++ S  +  ++        G+H+ FEY R GNPT  
Sbjct: 19   ATQAIHVGQEPEQW--TSRAVVPLISLSTTFKQAAP-------GQHSGFEYSRSGNPTRN 69

Query: 622  ALEKKMSALEKAESTVFVASGMYASVAMLSTLVPAGGHIVTTTDLYRKTRIYMETELPKR 801
             LEK ++AL+ A+  +  ASG+ A+V  ++ L+ AG  I+   D+Y  T  Y      + 
Sbjct: 70   CLEKAVAALDGAKYCLAFASGLAATVT-ITHLLKAGDQIICMDDVYGGTNRYFRQVASEF 128

Query: 802  GITMTVIRPADMDALQDALDNNNVSLFFTETPTNPFLRCIDIELVSNMCHNKG-ALLCID 978
            G+ ++ +  + +  L+ A+      L + ETPTNP L+ IDIE  +++ H +G  +L +D
Sbjct: 129  GLKISFVDCSKIKLLEAAI-TPETKLVWIETPTNPVLKMIDIEACAHIVHKRGDIILVVD 187

Query: 979  STFASPINQKALTLGADIVVHSATKYIAGHNDVIGGCISGRGE-LVSKVRIYHHVVGGVL 1155
            +TF SP  Q+ L LGADI + SATKY+ GH+DV+ G +S   E L +++R   + +G V 
Sbjct: 188  NTFMSPYFQRPLALGADICMCSATKYMNGHSDVVMGLVSVNCERLHNRLRFLQNSLGAVP 247

Query: 1156 NPNASYLILRGMKTLHLRVQCQNNTALRMAQFLEEHPKIARVYYPGLPSHPEHHIAKSQM 1335
            +P   YL  RG+KTLH+R++      + +AQFLE +P + +V YPGLPSHP+H +AK Q 
Sbjct: 248  SPLDCYLCNRGLKTLHVRMEKHFKNGMAVAQFLESNPGVEKVIYPGLPSHPQHELAKRQC 307

Query: 1336 TGFGGVVSFEVDGDFDSTRRFIDSVKIPYHAPSFGGCESIIDQPAIMSYWD-SKEQRDIY 1512
            TG  G+++F + G       F+ ++K+   A S GG ES+++ PAIM++    K  RD+ 
Sbjct: 308  TGCTGMITFYIKGTLQHAEIFLKNLKLFTLAESLGGFESLVELPAIMTHASVPKNDRDVL 367

Query: 1513 GIKDNLIRFSIGVEDFGDLKNDIVQAL 1593
            GI D LIR S+G+ED  DL  D+ QAL
Sbjct: 368  GISDTLIRLSVGLEDEKDLLEDLDQAL 394



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>P66875:METB_MYCTU Cystathionine gamma-synthase - Mycobacterium tuberculosis|
          Length = 388

 Score =  245 bits (625), Expect = 5e-64
 Identities = 144/389 (37%), Positives = 215/389 (55%), Gaps = 1/389 (0%)
 Frame = +1

Query: 430  LGSDASLAVHAGERLGRRIATDAITTPVVNTSAYWFSSSQELIDFKEGRHASFEYGRYGN 609
            +   A+ A+HAG R     AT A+  P+       ++SS    D   G    FEY R GN
Sbjct: 11   ISGPATRAIHAGYRPDP--ATGAVNVPI-------YASSTFAQDGVGGLRGGFEYARTGN 61

Query: 610  PTTEALEKKMSALEKAESTVFVASGMYASVAMLSTLVPAGGHIVTTTDLYRKTRIYMETE 789
            PT  ALE  ++A+E+       +SGM A+   L  ++  G H+V   D Y  T   ++  
Sbjct: 62   PTRAALEASLAAVEEGAFARAFSSGMAATDCALRAMLRPGDHVVIPDDAYGGTFRLIDKV 121

Query: 790  LPKRGITMTVIRPADMDALQDALDNNNVSLFFTETPTNPFLRCIDIELVSNMCHNKGALL 969
              +  +  T +R AD+DA+  A+      L + ETPTNP L   DI  ++ +  ++ A +
Sbjct: 122  FTRWDVQYTPVRLADLDAVGAAI-TPRTRLIWVETPTNPLLSIADITAIAELGTDRSAKV 180

Query: 970  CIDSTFASPINQKALTLGADIVVHSATKYIAGHNDVIGGC-ISGRGELVSKVRIYHHVVG 1146
             +D+TFASP  Q+ L LGAD+V+HS TKYI GH+DV+GG  ++   EL  +     +  G
Sbjct: 181  LVDNTFASPALQQPLRLGADVVLHSTTKYIGGHSDVVGGALVTNDEELDEEFAFLQNGAG 240

Query: 1147 GVLNPNASYLILRGMKTLHLRVQCQNNTALRMAQFLEEHPKIARVYYPGLPSHPEHHIAK 1326
             V  P  +YL +RG+KTL LR+Q  +  A  +A+FL +HP ++ V YPGLPSHP H IA 
Sbjct: 241  AVPGPFDAYLTMRGLKTLVLRMQRHSENACAVAEFLADHPSVSSVLYPGLPSHPGHEIAA 300

Query: 1327 SQMTGFGGVVSFEVDGDFDSTRRFIDSVKIPYHAPSFGGCESIIDQPAIMSYWDSKEQRD 1506
             QM GFGG+VS  +     + +      ++   A S GG ES+I+ P+ M++  +   + 
Sbjct: 301  RQMRGFGGMVSVRMRAGRRAAQDLCAKTRVFILAESLGGVESLIEHPSAMTHASTAGSQ- 359

Query: 1507 IYGIKDNLIRFSIGVEDFGDLKNDIVQAL 1593
               + D+L+R S+G+ED  DL  D+ QAL
Sbjct: 360  -LEVPDDLVRLSVGIEDIADLLGDLEQAL 387



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>P66876:METB_MYCBO Cystathionine gamma-synthase - Mycobacterium bovis|
          Length = 388

 Score =  245 bits (625), Expect = 5e-64
 Identities = 144/389 (37%), Positives = 215/389 (55%), Gaps = 1/389 (0%)
 Frame = +1

Query: 430  LGSDASLAVHAGERLGRRIATDAITTPVVNTSAYWFSSSQELIDFKEGRHASFEYGRYGN 609
            +   A+ A+HAG R     AT A+  P+       ++SS    D   G    FEY R GN
Sbjct: 11   ISGPATRAIHAGYRPDP--ATGAVNVPI-------YASSTFAQDGVGGLRGGFEYARTGN 61

Query: 610  PTTEALEKKMSALEKAESTVFVASGMYASVAMLSTLVPAGGHIVTTTDLYRKTRIYMETE 789
            PT  ALE  ++A+E+       +SGM A+   L  ++  G H+V   D Y  T   ++  
Sbjct: 62   PTRAALEASLAAVEEGAFARAFSSGMAATDCALRAMLRPGDHVVIPDDAYGGTFRLIDKV 121

Query: 790  LPKRGITMTVIRPADMDALQDALDNNNVSLFFTETPTNPFLRCIDIELVSNMCHNKGALL 969
              +  +  T +R AD+DA+  A+      L + ETPTNP L   DI  ++ +  ++ A +
Sbjct: 122  FTRWDVQYTPVRLADLDAVGAAI-TPRTRLIWVETPTNPLLSIADITAIAELGTDRSAKV 180

Query: 970  CIDSTFASPINQKALTLGADIVVHSATKYIAGHNDVIGGC-ISGRGELVSKVRIYHHVVG 1146
             +D+TFASP  Q+ L LGAD+V+HS TKYI GH+DV+GG  ++   EL  +     +  G
Sbjct: 181  LVDNTFASPALQQPLRLGADVVLHSTTKYIGGHSDVVGGALVTNDEELDEEFAFLQNGAG 240

Query: 1147 GVLNPNASYLILRGMKTLHLRVQCQNNTALRMAQFLEEHPKIARVYYPGLPSHPEHHIAK 1326
             V  P  +YL +RG+KTL LR+Q  +  A  +A+FL +HP ++ V YPGLPSHP H IA 
Sbjct: 241  AVPGPFDAYLTMRGLKTLVLRMQRHSENACAVAEFLADHPSVSSVLYPGLPSHPGHEIAA 300

Query: 1327 SQMTGFGGVVSFEVDGDFDSTRRFIDSVKIPYHAPSFGGCESIIDQPAIMSYWDSKEQRD 1506
             QM GFGG+VS  +     + +      ++   A S GG ES+I+ P+ M++  +   + 
Sbjct: 301  RQMRGFGGMVSVRMRAGRRAAQDLCAKTRVFILAESLGGVESLIEHPSAMTHASTAGSQ- 359

Query: 1507 IYGIKDNLIRFSIGVEDFGDLKNDIVQAL 1593
               + D+L+R S+G+ED  DL  D+ QAL
Sbjct: 360  -LEVPDDLVRLSVGIEDIADLLGDLEQAL 387



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>Q58DW2:CGL_BOVIN Cystathionine gamma-lyase - Bos taurus (Bovine)|
          Length = 405

 Score =  244 bits (622), Expect = 1e-63
 Identities = 145/387 (37%), Positives = 225/387 (58%), Gaps = 3/387 (0%)
 Frame = +1

Query: 442  ASLAVHAGERLGRRIATDAITTPVVNTSAYWFSSSQELIDFKEGRHASFEYGRYGNPTTE 621
            A+ A+H G+    +  + A+  P+        S S        G+H+ FEY R GNPT  
Sbjct: 19   ATQAIHVGQE-PEQWTSQAVVPPI--------SLSTTFKQGAPGQHSGFEYSRSGNPTRN 69

Query: 622  ALEKKMSALEKAESTVFVASGMYASVAMLSTLVPAGGHIVTTTDLYRKTRIYMETELPKR 801
             LEK ++AL+ A+ ++  ASG+ A+V  ++ L+ AG  I+   D+Y  T  Y      + 
Sbjct: 70   CLEKAVAALDGAKYSLAFASGLAATVT-ITHLLKAGDQIICMDDVYGGTNRYFRQVATEF 128

Query: 802  GITMTVIRPADMDALQDALDNNNVSLFFTETPTNPFLRCIDIELVSNMCHNKG-ALLCID 978
            G+ ++ +  +    L+ A+      L + ETPTNP L+ IDIE  ++  H  G  +L +D
Sbjct: 129  GLKISFVDCSKPKLLEAAI-TPETKLVWIETPTNPSLKMIDIEACAHTVHKHGDIILVVD 187

Query: 979  STFASPINQKALTLGADIVVHSATKYIAGHNDVIGGCISGRGE-LVSKVRIYHHVVGGVL 1155
            +TF S   Q+ L+LGADI ++SATKY+ G++DV+ G +S   E L  ++R   + +G V 
Sbjct: 188  NTFMSAYFQRPLSLGADICMYSATKYMNGYSDVVMGLVSLNSESLHDRLRFLQNSLGAVP 247

Query: 1156 NPNASYLILRGMKTLHLRVQCQNNTALRMAQFLEEHPKIARVYYPGLPSHPEHHIAKSQM 1335
            +P   YL  RG+KTL +R++      + +AQFLE +P++ +V YPGLPSHP+H +AK Q 
Sbjct: 248  SPIDCYLCNRGLKTLQVRMEKHFENGMAVAQFLESNPQVEKVIYPGLPSHPQHELAKRQC 307

Query: 1336 TGFGGVVSFEVDGDFDSTRRFIDSVKIPYHAPSFGGCESIIDQPAIMSYWD-SKEQRDIY 1512
            TG  G+V+F + G       F+ ++K+   A S GG ES+ + PAIM++    K  R++ 
Sbjct: 308  TGCPGMVTFYIKGSLQHAETFLQNLKLFTLAESLGGYESLAELPAIMTHASVPKSDREVL 367

Query: 1513 GIKDNLIRFSIGVEDFGDLKNDIVQAL 1593
            GI D LIR S+G+ED  DL +D+ QAL
Sbjct: 368  GISDTLIRLSVGLEDKQDLLDDLDQAL 394



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>P32929:CGL_HUMAN Cystathionine gamma-lyase - Homo sapiens (Human)|
          Length = 405

 Score =  243 bits (621), Expect = 1e-63
 Identities = 139/344 (40%), Positives = 209/344 (60%), Gaps = 3/344 (0%)
 Frame = +1

Query: 571  GRHASFEYGRYGNPTTEALEKKMSALEKAESTVFVASGMYASVAMLSTLVPAGGHIVTTT 750
            G+H+ FEY R GNPT   LEK ++AL+ A+  +  ASG+ A+V  ++ L+ AG  I+   
Sbjct: 53   GQHSGFEYSRSGNPTRNCLEKAVAALDGAKYCLAFASGLAATVT-ITHLLKAGDQIICMD 111

Query: 751  DLYRKTRIYMETELPKRGITMTVIRPADMDALQDALDNNNVSLFFTETPTNPFLRCIDIE 930
            D+Y  T  Y      + G+ ++ +  + +  L+ A+      L + ETPTNP  + IDIE
Sbjct: 112  DVYGGTNRYFRQVASEFGLKISFVDCSKIKLLEAAI-TPETKLVWIETPTNPTQKVIDIE 170

Query: 931  LVSNMCHNKG-ALLCIDSTFASPINQKALTLGADIVVHSATKYIAGHNDVIGGCISGRGE 1107
              +++ H  G  +L +D+TF SP  Q+ L LGADI ++SATKY+ GH+DV+ G +S   E
Sbjct: 171  GCAHIVHKHGDIILVVDNTFMSPYFQRPLALGADISMYSATKYMNGHSDVVMGLVSVNCE 230

Query: 1108 -LVSKVRIYHHVVGGVLNPNASYLILRGMKTLHLRVQCQNNTALRMAQFLEEHPKIARVY 1284
             L +++R   + +G V +P   YL  RG+KTLH+R++      + +AQFLE +P + +V 
Sbjct: 231  SLHNRLRFLQNSLGAVPSPIDCYLCNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVI 290

Query: 1285 YPGLPSHPEHHIAKSQMTGFGGVVSFEVDGDFDSTRRFIDSVKIPYHAPSFGGCESIIDQ 1464
            YPGLPSHP+H + K Q TG  G+V+F + G       F+ ++K+   A S GG ES+ + 
Sbjct: 291  YPGLPSHPQHELVKRQCTGCTGMVTFYIKGTLQHAEIFLKNLKLFTLAESLGGFESLAEL 350

Query: 1465 PAIMSYWD-SKEQRDIYGIKDNLIRFSIGVEDFGDLKNDIVQAL 1593
            PAIM++    K  RD+ GI D LIR S+G+ED  DL  D+ QAL
Sbjct: 351  PAIMTHASVLKNDRDVLGISDTLIRLSVGLEDEEDLLEDLDQAL 394



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>P46807:METB_MYCLE Cystathionine gamma-synthase - Mycobacterium leprae|
          Length = 388

 Score =  239 bits (610), Expect = 3e-62
 Identities = 141/386 (36%), Positives = 212/386 (54%), Gaps = 1/386 (0%)
 Frame = +1

Query: 442  ASLAVHAGERLGRRIATDAITTPVVNTSAYWFSSSQELIDFKEGRHASFEYGRYGNPTTE 621
            A+ A+HAG R     AT A+  P+  +S +      EL          FEY R GNP   
Sbjct: 15   ATKAIHAGYRPDP--ATGAVNVPIYASSTFAQDGVGEL-------RGGFEYARTGNPMRA 65

Query: 622  ALEKKMSALEKAESTVFVASGMYASVAMLSTLVPAGGHIVTTTDLYRKTRIYMETELPKR 801
            ALE  ++ +E+       +SGM AS   L  ++  G H++   D+Y  T   ++    + 
Sbjct: 66   ALEASLATVEEGVFARAFSSGMAASDCALRVMLRPGDHVIIPDDVYGGTFRLIDKVFTQW 125

Query: 802  GITMTVIRPADMDALQDALDNNNVSLFFTETPTNPFLRCIDIELVSNMCHNKGALLCIDS 981
             +  T +  +D+DA++ A+  +   L + ETPTNP L   DI  +  +       + +D+
Sbjct: 126  NVDYTPVPLSDLDAVRAAI-TSRTRLIWVETPTNPLLSIADITSIGELGKKHSVKVLVDN 184

Query: 982  TFASPINQKALTLGADIVVHSATKYIAGHNDVIGGC-ISGRGELVSKVRIYHHVVGGVLN 1158
            TFASP  Q+ L LGAD+V+HS TKYI GH+DV+GG  ++   EL        +  G V +
Sbjct: 185  TFASPALQQPLMLGADVVLHSTTKYIGGHSDVVGGALVTNDEELDQAFGFLQNGAGAVPS 244

Query: 1159 PNASYLILRGMKTLHLRVQCQNNTALRMAQFLEEHPKIARVYYPGLPSHPEHHIAKSQMT 1338
            P  +YL +RG+KTL LR+Q  N  A+ +A+FL  HP ++ V YPGLPSHP H +A  QM 
Sbjct: 245  PFDAYLTMRGLKTLVLRMQRHNENAITVAEFLAGHPSVSAVLYPGLPSHPGHEVAARQMR 304

Query: 1339 GFGGVVSFEVDGDFDSTRRFIDSVKIPYHAPSFGGCESIIDQPAIMSYWDSKEQRDIYGI 1518
            GFGG+VS  +     + +      K+   A S GG ES+I+QP+ M++  +   +    +
Sbjct: 305  GFGGMVSLRMRAGRLAAQDLCARTKVFTLAESLGGVESLIEQPSAMTHASTTGSQ--LEV 362

Query: 1519 KDNLIRFSIGVEDFGDLKNDIVQALD 1596
             D+L+R S+G+ED GDL  D+ QAL+
Sbjct: 363  PDDLVRLSVGIEDVGDLLCDLKQALN 388



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>P13254:MEGL_PSEPU Methionine gamma-lyase - Pseudomonas putida|
          Length = 398

 Score =  234 bits (598), Expect = 7e-61
 Identities = 130/369 (35%), Positives = 216/369 (58%), Gaps = 3/369 (0%)
 Frame = +1

Query: 496  AITTPVVNTSAYWFSSSQELIDFKEGRHASFEYGRYGNPTTEALEKKMSALEKAESTVFV 675
            A+  PV  T+ + F + +       G  A   Y R  NPT   LE +M++LE  E+ + +
Sbjct: 27   ALVPPVYQTATFTFPTVEYGAACFAGEQAGHFYSRISNPTLNLLEARMASLEGGEAGLAL 86

Query: 676  ASGMYASVAMLSTLVPAGGHIVTTTDLYRKTRIYMETELPKRGITMTVIRPADMDALQDA 855
            ASGM A  + L TL+  G  ++    LY  T  ++   + + G+ +  +  AD+ AL+ A
Sbjct: 87   ASGMGAITSTLWTLLRPGDEVLLGNTLYGCTFAFLHHGIGEFGVKLRHVDMADLQALEAA 146

Query: 856  LDNNNVSLFFTETPTNPFLRCIDIELVSNMCHNKGALLCIDSTFASPINQKALTLGADIV 1035
            +      ++F E+P NP +   DI  V+ +    GA + +D+T+ +P  Q+ L LGAD+V
Sbjct: 147  MTPATRVIYF-ESPANPNMHMADIAGVAKIARKHGATVVVDNTYCTPYLQRPLELGADLV 205

Query: 1036 VHSATKYIAGHNDVIGGCISGRGELVSKVRIY--HHVVGGVLNPNASYLILRGMKTLHLR 1209
            VHSATKY++GH D+  G + G   LV ++R+     + G VL+P+ + L++RG+KTL+LR
Sbjct: 206  VHSATKYLSGHGDITAGIVVGSQALVDRIRLQGLKDMTGAVLSPHDAALLMRGIKTLNLR 265

Query: 1210 VQCQNNTALRMAQFLEEHPKIARVYYPGLPSHPEHHIAKSQMTGFGGVVSFEVDGDFDST 1389
            +      A  +A+FL   P++  ++YPGL S P++ +A+ QM+  GG+++FE+ G   + 
Sbjct: 266  MDRHCANAQVLAEFLARQPQVELIHYPGLASFPQYTLARQQMSQPGGMIAFELKGGIGAG 325

Query: 1390 RRFIDSVKIPYHAPSFGGCESIIDQPAIMSYWD-SKEQRDIYGIKDNLIRFSIGVEDFGD 1566
            RRF++++++   A S G  ES+   PA M++   + E+R  YGI + L+R S+G+ED  D
Sbjct: 326  RRFMNALQLFSRAVSLGDAESLAQHPASMTHSSYTPEERAHYGISEGLVRLSVGLEDIDD 385

Query: 1567 LKNDIVQAL 1593
            L  D+ QAL
Sbjct: 386  LLADVQQAL 394



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>P55216:CGL_CAEEL Putative cystathionine gamma-lyase - Caenorhabditis elegans|
          Length = 392

 Score =  234 bits (597), Expect = 9e-61
 Identities = 131/346 (37%), Positives = 206/346 (59%), Gaps = 5/346 (1%)
 Frame = +1

Query: 571  GRHASFEYGRYGNPTTEALEKKMSALEKAESTVFVASGMYASVAMLSTLVPAGGHIVTTT 750
            G     +Y R GNPT + L+K ++ALE A+     +SG+ A+ A+++ L+  G HIV + 
Sbjct: 42   GEPKGHDYSRAGNPTRDVLQKNLAALEDAKHCQVFSSGLAATSAIIN-LLKYGDHIVCSD 100

Query: 751  DLYRKTRIYME-TELPKRGITMTVIRPADMDALQDALDNNNVSLFFTETPTNPFLRCIDI 927
            D+Y  T+ Y+    +P  G+ +  +   D+  L+ A+  N   ++F E+P+NP L+ +DI
Sbjct: 101  DVYGGTQRYIRRVAVPNHGLEVDSVDLTDVQNLEKAIKPNTKMVWF-ESPSNPLLKVVDI 159

Query: 928  ELVSNMCH--NKGALLCIDSTFASPINQKALTLGADIVVHSATKYIAGHNDVI-GGCISG 1098
              V       N   ++ +D+TF SP  Q+ ++LGAD+VVHS TKYI GH+DV+ G  I+ 
Sbjct: 160  AAVVQTAKKANPEIVVVVDNTFMSPYFQRPISLGADVVVHSITKYINGHSDVVMGAVITD 219

Query: 1099 RGELVSKVRIYHHVVGGVLNPNASYLILRGMKTLHLRVQCQNNTALRMAQFLEEHPKIAR 1278
              E    +      VG V +P   +L+ RG+KTLH+R++     AL +A++LE + +I  
Sbjct: 220  NDEFQQHLFFMQLAVGAVPSPFDCFLVNRGLKTLHIRMRAHYENALAVAKYLEANDRIES 279

Query: 1279 VYYPGLPSHPEHHIAKSQMTGFGGVVSFEVDGDFDSTRRFIDSVKIPYHAPSFGGCESII 1458
            V YP LPSHP+H + + Q  G  G++SF + G+   +R F+ ++K+   A S GG ES+ 
Sbjct: 280  VLYPALPSHPQHEVHEKQTKGMSGMISFYLKGELQESRAFLSALKVFTLAESLGGYESLA 339

Query: 1459 DQPAIMSYWD-SKEQRDIYGIKDNLIRFSIGVEDFGDLKNDIVQAL 1593
            + P+IM++     E R + GI DNLIR S+G+ED  DL  D+ QAL
Sbjct: 340  ELPSIMTHASVPAETRIVLGITDNLIRISVGIEDLDDLVADLDQAL 385



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>P24601:METB_HERAU Probable cystathionine gamma-synthase - Herpetosiphon aurantiacus|
            (Herpetosiphon giganteus)
          Length = 319

 Score =  231 bits (589), Expect = 8e-60
 Identities = 124/326 (38%), Positives = 192/326 (58%), Gaps = 1/326 (0%)
 Frame = +1

Query: 442  ASLAVHAGERLGRRIATDAITTPVVNTSAYWFSSSQELIDFKEGRHASFEYGRYGNPTTE 621
            A+ A+HAG+       T A+  P+  TS Y    +Q  +    G H  +EY R  NPT  
Sbjct: 6    ATRAIHAGQ--DPESVTGAVIVPIYQTSTY----AQRGV----GDHTGYEYSRTDNPTRT 55

Query: 622  ALEKKMSALEKAESTVFVASGMYASVAMLSTLVPAGGHIVTTTDLYRKTRIYMETELPKR 801
            AL+  ++ALE+A+  +  ASG+ AS  ++  ++ AG H++   D+Y  T    +  + + 
Sbjct: 56   ALQTCLAALEEAKHALVFASGLGASTTLM-LMLKAGDHVICGDDVYGGTYRLFQRVMTEH 114

Query: 802  GITMTVIRPADMDALQDALDNNNVSLFFTETPTNPFLRCIDIELVSNMCHNKGALLCIDS 981
            G++   I  AD +A++ A+   N  L + ETPTNP L+   I  ++ +    G    +D+
Sbjct: 115  GLSFDFIDMADPEAVRAAI-KPNTRLIWLETPTNPLLKLAPIAAITRVAREHGIWTIVDN 173

Query: 982  TFASPINQKALTLGADIVVHSATKYIAGHNDVIGGCI-SGRGELVSKVRIYHHVVGGVLN 1158
            TFASP NQ+ +TLGAD+V+HS TKYI GH+DV+GG I +   EL  K++   +  G V  
Sbjct: 174  TFASPYNQRPITLGADMVLHSTTKYIGGHSDVVGGAIMTSNDELYEKLKFLQNAAGAVPG 233

Query: 1159 PNASYLILRGMKTLHLRVQCQNNTALRMAQFLEEHPKIARVYYPGLPSHPEHHIAKSQMT 1338
            P   +L+LRG+KTL +R++     AL +AQFL EHP + +V YPGLPSHP+H++A+ QM 
Sbjct: 234  PFDCWLVLRGVKTLSIRMRDDERNALAIAQFLTEHPGVEKVIYPGLPSHPQHNLAREQMR 293

Query: 1339 GFGGVVSFEVDGDFDSTRRFIDSVKI 1416
            GFGG++S  + G  ++    +   K+
Sbjct: 294  GFGGMISILLKGGAEAANAMVSKTKL 319



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>Q8VCN5:CGL_MOUSE Cystathionine gamma-lyase - Mus musculus (Mouse)|
          Length = 398

 Score =  229 bits (583), Expect = 4e-59
 Identities = 131/344 (38%), Positives = 206/344 (59%), Gaps = 3/344 (0%)
 Frame = +1

Query: 571  GRHASFEYGRYGNPTTEALEKKMSALEKAESTVFVASGMYASVAMLSTLVPAGGHIVTTT 750
            G+ + FEY R GNPT   LEK ++AL+ A+ ++  ASG+ A++  ++ L+ AG  I+   
Sbjct: 52   GQSSGFEYSRSGNPTRNCLEKAVAALDGAKHSLAFASGLAATIT-ITHLLKAGDEIICMD 110

Query: 751  DLYRKTRIYMETELPKRGITMTVIRPADMDALQDALDNNNVSLFFTETPTNPFLRCIDIE 930
            ++Y  T  Y      + G+ ++ +  +    L+ A+      L + ETPTNP L+  DI 
Sbjct: 111  EVYGGTNRYFRRVASEFGLKISFVDCSKTKLLEAAI-TPQTKLVWIETPTNPTLKLADIG 169

Query: 931  LVSNMCHNKG-ALLCIDSTFASPINQKALTLGADIVVHSATKYIAGHNDVIGGCIS-GRG 1104
              + + H +G  +L +D+TF S   Q+ L LGADI + SATKY+ GH+DV+ G +S    
Sbjct: 170  ACAQIVHKRGDIILVVDNTFMSAYFQRPLALGADICMCSATKYMNGHSDVVMGLVSVNSD 229

Query: 1105 ELVSKVRIYHHVVGGVLNPNASYLILRGMKTLHLRVQCQNNTALRMAQFLEEHPKIARVY 1284
            +L S++R   + +G V +P   YL  RG+KTL +R++      + +A+FLE +P++ +V 
Sbjct: 230  DLNSRLRFLQNSLGAVPSPFDCYLCCRGLKTLQVRMEKHFKNGMAVARFLETNPRVEKVV 289

Query: 1285 YPGLPSHPEHHIAKSQMTGFGGVVSFEVDGDFDSTRRFIDSVKIPYHAPSFGGCESIIDQ 1464
            YPGLPSHP+H +AK Q +G  G+VSF + G     + F+ ++K+   A S GG ES+ + 
Sbjct: 290  YPGLPSHPQHELAKRQCSGCPGMVSFYIKGALQHAKAFLKNLKLFTLAESLGGYESLAEL 349

Query: 1465 PAIMSYWDSKEQ-RDIYGIKDNLIRFSIGVEDFGDLKNDIVQAL 1593
            PAIM++    E+ R   GI D LIR S+G+ED  DL  D+ +AL
Sbjct: 350  PAIMTHASVPEKDRATLGINDTLIRLSVGLEDEQDLLEDLDRAL 393



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>P53780:METC_ARATH Cystathionine beta-lyase, chloroplast precursor - Arabidopsis|
            thaliana (Mouse-ear cress)
          Length = 464

 Score =  228 bits (580), Expect = 8e-59
 Identities = 130/365 (35%), Positives = 210/365 (57%), Gaps = 2/365 (0%)
 Frame = +1

Query: 493  DAITTPVVNTSAYWFSSSQELIDFKEGRHASFEYGRYGNPTTEALEKKMSALEKAESTVF 672
            DA++TP+  T+ +   S+ E        +  ++Y R GNPT +ALE  ++ L+KA+    
Sbjct: 102  DAMSTPLYQTATFKQPSAIE--------NGPYDYTRSGNPTRDALESLLAKLDKADRAFC 153

Query: 673  VASGMYASVAMLSTLVPAGGHIVTTTDLYRKTRIYMETELPKRGITMTVIRPADMDALQD 852
              SGM A+++ ++ L+  G  IV   D+Y  +   +   +P+ G+ +  +    +D +  
Sbjct: 154  FTSGM-AALSAVTHLIKNGEEIVAGDDVYGGSDRLLSQVVPRSGVVVKRVNTTKLDEVAA 212

Query: 853  ALDNNNVSLFFTETPTNPFLRCIDIELVSNMCHNKGALLCIDSTFASPINQKALTLGADI 1032
            A+      L + E+PTNP  +  DI  +S M H +GAL+ +D++  SP+  + L LGADI
Sbjct: 213  AI-GPQTKLVWLESPTNPRQQISDIRKISEMAHAQGALVLVDNSIMSPVLSRPLELGADI 271

Query: 1033 VVHSATKYIAGHNDVIGGCISGRGE-LVSKVRIYHHVVGGVLNPNASYLILRGMKTLHLR 1209
            V+HSATK+IAGH+DV+ G ++ +GE L  +V    +  G  L P   +L LRG+KT+ LR
Sbjct: 272  VMHSATKFIAGHSDVMAGVLAVKGEKLAKEVYFLQNSEGSGLAPFDCWLCLRGIKTMALR 331

Query: 1210 VQCQNNTALRMAQFLEEHPKIARVYYPGLPSHPEHHIAKSQMTGFGGVVSFEVDGDFDST 1389
            ++ Q   A ++A +L  HP++ +VYY GLP HP HH+  SQ  G G V SF + G    +
Sbjct: 332  IEKQQENARKIAMYLSSHPRVKKVYYAGLPDHPGHHLHFSQAKGAGSVFSF-ITGSVALS 390

Query: 1390 RRFIDSVKIPYHAPSFGGCESIIDQPAIMSYWD-SKEQRDIYGIKDNLIRFSIGVEDFGD 1566
            +  +++ K    A SFG  +S+I  P  MS+     E R+  G+ ++L+R S G+ED  D
Sbjct: 391  KHLVETTKYFSIAVSFGSVKSLISMPCFMSHASIPAEVREARGLTEDLVRISAGIEDVDD 450

Query: 1567 LKNDI 1581
            L +D+
Sbjct: 451  LISDL 455



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>P18757:CGL_RAT Cystathionine gamma-lyase - Rattus norvegicus (Rat)|
          Length = 398

 Score =  224 bits (570), Expect = 1e-57
 Identities = 129/344 (37%), Positives = 202/344 (58%), Gaps = 3/344 (0%)
 Frame = +1

Query: 571  GRHASFEYGRYGNPTTEALEKKMSALEKAESTVFVASGMYASVAMLSTLVPAGGHIVTTT 750
            G+ + F Y R GNPT   LEK ++AL+ A+  +  A G+ A+   ++ L+ AG  ++   
Sbjct: 52   GQSSGFVYSRSGNPTRNCLEKAVAALDGAKHCLTFARGL-AATTTITHLLKAGDEVICMD 110

Query: 751  DLYRKTRIYMETELPKRGITMTVIRPADMDALQDALDNNNVSLFFTETPTNPFLRCIDIE 930
            ++Y  T  Y      + G+ ++ +  +    L+ A+      L + ETPTNP L+  DI+
Sbjct: 111  EVYGGTNRYFRRVASEFGLKISFVDCSKTKLLEAAI-TPQTKLVWIETPTNPTLKLADIK 169

Query: 931  LVSNMCH-NKGALLCIDSTFASPINQKALTLGADIVVHSATKYIAGHNDVIGGCISGRGE 1107
              + + H +K  +L +D+TF S   Q+ L LGADI + SATKY+ GH+DV+ G +S   +
Sbjct: 170  ACAQIVHKHKDIILVVDNTFMSAYFQRPLALGADICMCSATKYMNGHSDVVMGLVSVTSD 229

Query: 1108 -LVSKVRIYHHVVGGVLNPNASYLILRGMKTLHLRVQCQNNTALRMAQFLEEHPKIARVY 1284
             L  ++R   + +G V +P   YL  RG+KTL +R++      + +A+FLE +P++ +V 
Sbjct: 230  DLNERLRFLQNSLGAVPSPFDCYLCCRGLKTLQIRMEKHFRNGMAVARFLESNPRVEKVI 289

Query: 1285 YPGLPSHPEHHIAKSQMTGFGGVVSFEVDGDFDSTRRFIDSVKIPYHAPSFGGCESIIDQ 1464
            YPGLPSHP+H +AK Q TG  G+VSF + G     + F+ ++K+   A S GG ES+ + 
Sbjct: 290  YPGLPSHPQHELAKRQCTGCPGMVSFYIKGTLQHAQVFLKNIKLFALAESLGGYESLAEL 349

Query: 1465 PAIMSYWDSKEQ-RDIYGIKDNLIRFSIGVEDFGDLKNDIVQAL 1593
            PAIM++    E+ R   GI D LIR S+G+ED  DL  D+ QAL
Sbjct: 350  PAIMTHASVPEKDRATLGISDTLIRLSVGLEDEKDLLEDLGQAL 393



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>P31373:CYS3_YEAST Cystathionine gamma-lyase - Saccharomyces cerevisiae (Baker's yeast)|
          Length = 394

 Score =  210 bits (535), Expect = 1e-53
 Identities = 135/393 (34%), Positives = 213/393 (54%), Gaps = 9/393 (2%)
 Frame = +1

Query: 442  ASLAVHAGERLGRRIATDAITTPVVNTSAYWFSSSQELIDFKEGRHASFEYGRYGNPTTE 621
            A+ A+HAGE +       ++  P+  ++ +  SS    I        ++EY R  NP  E
Sbjct: 10   ATKAIHAGEHVD---VHGSVIEPISLSTTFKQSSPANPI-------GTYEYSRSQNPNRE 59

Query: 622  ALEKKMSALEKAESTVFVASGMYASVAMLSTLVPAGGHIVTTTDLYRKTRIYMETELPKR 801
             LE+ ++ALE A+  +  +SG   +  +L +L P G H V+  D+Y  T  Y        
Sbjct: 60   NLERAVAALENAQYGLAFSSGSATTATILQSL-PQGSHAVSIGDVYGGTHRYFTKVANAH 118

Query: 802  GITMTVIRPADMDALQDALDNNNVSLFFTETPTNPFLRCIDIELVSNMCHNKGA----LL 969
            G+  +       D  Q  L   N  L + ETPTNP L+  DI+ V+++     A    +L
Sbjct: 119  GVETSFTNDLLNDLPQ--LIKENTKLVWIETPTNPTLKVTDIQKVADLIKKHAAGQDVIL 176

Query: 970  CIDSTFASPINQKALTLGADIVVHSATKYIAGHNDVIGGCISGRGE-LVSKVRIYHHVVG 1146
             +D+TF SP     L  GADIVVHSATKYI GH+DV+ G ++   + L  +++   + +G
Sbjct: 177  VVDNTFLSPYISNPLNFGADIVVHSATKYINGHSDVVLGVLATNNKPLYERLQFLQNAIG 236

Query: 1147 GVLNPNASYLILRGMKTLHLRVQCQNNTALRMAQFL-EEHPKIARVYYPGLPSHPEHHIA 1323
             + +P  ++L  RG+KTLHLRV+    +A ++A+FL  +   +  V YPGL +HP + + 
Sbjct: 237  AIPSPFDAWLTHRGLKTLHLRVRQAALSANKIAEFLAADKENVVAVNYPGLKTHPNYDVV 296

Query: 1324 KSQMTGF--GGVVSFEVDGDFDSTRRFIDSVKIPYHAPSFGGCESIIDQPAIMSYWD-SK 1494
              Q      GG++SF + G  ++  +F  S ++   A S GG ES+++ PA+M++    K
Sbjct: 297  LKQHRDALGGGMISFRIKGGAEAASKFASSTRLFTLAESLGGIESLLEVPAVMTHGGIPK 356

Query: 1495 EQRDIYGIKDNLIRFSIGVEDFGDLKNDIVQAL 1593
            E R+  G+ D+L+R S+G+ED  DL  DI QAL
Sbjct: 357  EAREASGVFDDLVRISVGIEDTDDLLEDIKQAL 389



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>P44502:METB_HAEIN Cystathionine gamma-synthase - Haemophilus influenzae|
          Length = 369

 Score =  197 bits (502), Expect = 9e-50
 Identities = 128/385 (33%), Positives = 198/385 (51%), Gaps = 3/385 (0%)
 Frame = +1

Query: 445  SLAVHAGERLGRRIATDAITTPVVNTSAYWFSSSQELIDFKEGRHASFEYGRYGNPTTEA 624
            +L   AG R   R  T A++ P+  ++AY             G    F+Y R  NPT   
Sbjct: 9    TLLAQAGNRSDER--TGAVSAPIFLSTAYGHCGI--------GESTGFDYTRTKNPTRTV 58

Query: 625  LEKKMSALEKAESTVFVASGMYASVAMLSTLVPAGGHIVTTTDLYRKTRIYMETELPKRG 804
            LE+ ++ LE  +     +SGM A++ +L TL  A    + ++D+Y  T   ++       
Sbjct: 59   LEETIAKLENGDRGFAFSSGM-AAIQVLMTLFTAPDEWIVSSDVYGGTYRLLDFSYKNNN 117

Query: 805  ITMTV-IRPADMDALQDALDNNNVSLFFTETPTNPFLRCIDIELVSNMCHNKGALLCIDS 981
                V +  A   A++ A+ N N    F ETP+NP +   D+  ++ +      +L +D+
Sbjct: 118  SVKPVYVNTASASAIEAAI-NPNTKAIFIETPSNPLMEECDVVEIAKLAKKHNLMLIVDN 176

Query: 982  TFASPINQKALTLGADIVVHSATKYIAGHNDVIGGCISGRG-ELVSKVRIYHHVVGGVLN 1158
            TF +P+  + L LGAD+V+HS TKYIAGHND + G I  +G EL  ++    +  G VL+
Sbjct: 177  TFLTPVLSRPLDLGADVVIHSGTKYIAGHNDALVGLIVAKGQELCDRIAYIQNGAGAVLS 236

Query: 1159 PNASYLILRGMKTLHLRVQCQNNTALRMAQFLEEHPKIARVYYPGLPSHPEHHIAKSQMT 1338
            P  S+L +RGMKTL LR++     A  +A+FL+  P++  V YP                
Sbjct: 237  PFDSWLTIRGMKTLSLRMKRHQENAQAIAEFLKAQPQVESVLYPNK-------------- 282

Query: 1339 GFGGVVSFEVDGDFDSTRRFIDSVKIPYHAPSFGGCESIIDQPAIMSYWDSKE-QRDIYG 1515
              GG++SF +  D      F+ S+K+   A S GG ES I  PA  ++ D  E +R   G
Sbjct: 283  --GGMLSFRLQ-DEAWVNTFLKSIKLITFAESLGGTESFITYPATQTHMDIPESERVARG 339

Query: 1516 IKDNLIRFSIGVEDFGDLKNDIVQA 1590
            I + L+RFS+G+ED  D+K D++QA
Sbjct: 340  ITNTLLRFSVGIEDVEDIKADLLQA 364



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>P00935:METB_ECOLI Cystathionine gamma-synthase - Escherichia coli|
          Length = 386

 Score =  197 bits (501), Expect = 1e-49
 Identities = 119/351 (33%), Positives = 192/351 (54%), Gaps = 3/351 (0%)
 Frame = +1

Query: 538  SSSQELIDFKEGRHASFEYGRYGNPTTEALEKKMSALEKAESTVFVASGMYASVAMLSTL 717
            SS+     F E R  + +Y R GNPT + +++ ++ LE     V   +GM A   + +  
Sbjct: 30   SSTYNFTGFNEPR--AHDYSRRGNPTRDVVQRALAELEGGAGAVLTNTGMSAIHLVTTVF 87

Query: 718  VPAGGHIVTTTDLYRKTRIYMETELPKRGITMTV-IRPADMDALQDALDNNNVSLFFTET 894
            +  G  +V   D Y  +    ++ L KRG    + +   D  AL+ AL      L   E+
Sbjct: 88   LKPGDLLVAPHDCYGGSYRLFDS-LAKRGCYRVLFVDQGDEQALRAALAEKP-KLVLVES 145

Query: 895  PTNPFLRCIDIELVSNMCHNKGALLCIDSTFASPINQKALTLGADIVVHSATKYIAGHND 1074
            P+NP LR +DI  + ++    GA+  +D+TF SP  Q  L LGAD+V+HS TKY+ GH+D
Sbjct: 146  PSNPLLRVVDIAKICHLAREVGAVSVVDNTFLSPALQNPLALGADLVLHSCTKYLNGHSD 205

Query: 1075 VIGGCISGRG-ELVSKVRIYHHVVGGVLNPNASYLILRGMKTLHLRVQCQNNTALRMAQF 1251
            V+ G +  +  ++V+++  + + +G       SYL+LRG++TL  R++     A  + ++
Sbjct: 206  VVAGVVIAKDPDVVTELAWWANNIGVTGGAFDSYLLLRGLRTLVPRMELAQRNAQAIVKY 265

Query: 1252 LEEHPKIARVYYPGLPSHPEHHIAKSQMTGFGGVVSFEVDGDFDSTRRFIDSVKIPYHAP 1431
            L+  P + ++Y+P LP +  H IA  Q  GFG ++SFE+DGD  + RRF+  + +   A 
Sbjct: 266  LQTQPLVKKLYHPSLPENQGHEIAARQQKGFGAMLSFELDGDEQTLRRFLGGLSLFTLAE 325

Query: 1432 SFGGCESIIDQPAIMSYWD-SKEQRDIYGIKDNLIRFSIGVEDFGDLKNDI 1581
            S GG ES+I   A M++   + E R   GI + L+R S G+ED  DL  D+
Sbjct: 326  SLGGVESLISHAATMTHAGMAPEARAAAGISETLLRISTGIEDGEDLIADL 376



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>O13326:CYSD_SCHPO O-acetylhomoserine - Schizosaccharomyces pombe (Fission yeast)|
          Length = 429

 Score =  191 bits (486), Expect = 7e-48
 Identities = 128/421 (30%), Positives = 206/421 (48%), Gaps = 37/421 (8%)
 Frame = +1

Query: 445  SLAVHAGERLGRRIATDAITTPVVNTSAYWFSSSQELIDFKEGRHASFEYGRYGNPTTEA 624
            +L +HAG+      AT +   P+  T++Y F            +   + Y R  NPT + 
Sbjct: 10   TLQLHAGQEPDA--ATSSRAVPIYATTSYVFRDCDHGGRLFGLQEPGYIYSRMMNPTADV 67

Query: 625  LEKKMSALEKAESTVFVASGMYASVAMLSTLVPAGGHIVTTTDLYRKTRIYMETELPKRG 804
             EK+++ALE   + +  +SG  A    L+TL  AG +IV+T+ LY  T    +  LP+ G
Sbjct: 68   FEKRIAALEHGAAAIATSSGTSALFMALTTLAKAGDNIVSTSYLYGGTYNLFKVTLPRLG 127

Query: 805  ITMTVIRPADMDALQDALDNNNVSLFFTETPTNPFLRCIDIELVSNMCHNKGALLCIDST 984
            IT   +   D + L   +D N  ++ + E+  NP     D E ++ + H  G  L +D+T
Sbjct: 128  ITTKFVNGDDPNDLAAQIDENTKAV-YVESIGNPMYNVPDFERIAEVAHAAGVPLMVDNT 186

Query: 985  F-ASPINQKALTLGADIVVHSATKYIAGHNDVIGGCISGRGELVSKVRI----------- 1128
            F       + +  GADIV HSATK+I GH   IGG I   G+   K              
Sbjct: 187  FGGGGYLVRPIDHGADIVTHSATKWIGGHGTTIGGVIVDSGKFDWKKNSKRFPEFNEPHP 246

Query: 1129 -YHHV----------------------VGGVLNPNASYLILRGMKTLHLRVQCQNNTALR 1239
             YH +                      VGG  NP   +L+L+G++TL LR++     A  
Sbjct: 247  GYHGMVFTETFGNLAYAFACRTQTLRDVGGNANPFGVFLLLQGLETLSLRMERHVQNAFA 306

Query: 1240 MAQFLEEHPKIARVYYPGLPSHPEHHIAKSQM-TGFGGVVSFEVDGDFDSTRRFIDSVKI 1416
            +A++LE+HPK+  V YPGL SH  H +AK  +  G+G V+SF   G  D +R+ ++++K+
Sbjct: 307  LAKYLEKHPKVNWVSYPGLESHVSHKLAKKYLKNGYGAVLSFGAKGGPDQSRKVVNALKL 366

Query: 1417 PYHAPSFGGCESIIDQPAIMSYWDSKEQRDI-YGIKDNLIRFSIGVEDFGDLKNDIVQAL 1593
                 + G  ++++  PA  ++    ++  I  G+  +LIR ++G+E   D+  D  QAL
Sbjct: 367  ASQLANVGDAKTLVIAPAYTTHLQLTDEEQISAGVTKDLIRVAVGIEHIDDIIADFAQAL 426

Query: 1594 D 1596
            +
Sbjct: 427  E 427



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>Q52811:METC_RHIL3 Putative cystathionine beta-lyase - Rhizobium leguminosarum bv.|
            viciae (strain 3841)
          Length = 396

 Score =  190 bits (483), Expect = 1e-47
 Identities = 120/366 (32%), Positives = 193/366 (52%), Gaps = 5/366 (1%)
 Frame = +1

Query: 499  ITTPVVNTSAYWFSSSQELIDFKEGRHASFEYGRYGNPTTEALEKKMSALEKAESTVFVA 678
            I  PVV+ S   F +++ +    E R   + YG  G PTT+AL + + ALE +  T+ V 
Sbjct: 31   INPPVVHASTVLFPNARAM----ETRTQKYTYGTRGTPTTDALCEAIDALEGSAGTILVP 86

Query: 679  SGMYASVAMLSTLVPAGGHIVTTTDLYRKTRIYMETELPKRGITMTVIRPADMDALQDAL 858
            SG+ A        V AG H +    +Y  TR + +T L + G+ +    P ++ A  + L
Sbjct: 87   SGLAAVTIPFLGFVAAGDHALVVDSVYGPTRHFCDTMLKRLGVEVEYYHP-EIGAGIETL 145

Query: 859  DNNNVSLFFTETPTNPFLRCIDIELVSNMCHNKGALLCIDSTFASPINQKALTLGADIVV 1038
              +N  L  TE P +      DI  +S + H  GA++ +D+T+A+P+  + L  G DI +
Sbjct: 146  FRSNTKLVHTEAPGSNTFEMQDIPAISAVAHRHGAVVMMDNTWATPVYFRPLDHGVDISI 205

Query: 1039 HSATKYIAGHNDVIGGCISGRGELVSKVRIYHHVVGGVLNPNASYLILRGMKTLHLRVQC 1218
            H++TKY +GH+D++ G +S   E   +++  + V+G    P+ +Y ILRG++T+ LR++ 
Sbjct: 206  HASTKYPSGHSDILLGTVSANAEHWERLKEANGVLGICGAPDDAYQILRGLRTMGLRLER 265

Query: 1219 QNNTALRMAQFLEEHPKIARVYYPGLPSHPEHHIAKSQMTGFGGVVSFEVDGDFDSTRR- 1395
               +AL +A++LE    +ARV +P LPS P HH+ K    G  G+ SF +  D     R 
Sbjct: 266  HYESALDIAKWLEGRDDVARVLHPALPSFPSHHLWKRDFKGASGIFSFVLAADGPEKSRA 325

Query: 1396 ----FIDSVKIPYHAPSFGGCESIIDQPAIMSYWDSKEQRDIYGIKDNLIRFSIGVEDFG 1563
                F+D+++I     S+GG ES+     +     +K   D       +IR  IG+ED  
Sbjct: 326  KAHAFLDALRIFGLGYSWGGFESLALHAYLNDRTVAKAPTD-----GPVIRLQIGIEDVA 380

Query: 1564 DLKNDI 1581
            DLK DI
Sbjct: 381  DLKADI 386



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>Q59829:CYSA_STRCO Putative cystathionine gamma-lyase - Streptomyces coelicolor|
          Length = 392

 Score =  183 bits (464), Expect = 2e-45
 Identities = 125/347 (36%), Positives = 185/347 (53%), Gaps = 9/347 (2%)
 Frame = +1

Query: 586  FEYGRYGNPTTEALEKKMSALEK-----AESTVFVASGMYASVAMLSTLVPAGGHIVTTT 750
            + YGR  NPT   LE  +  LE       E+ VF ASGM A  ++L + + AG   V   
Sbjct: 61   YTYGRDENPTWTRLESAIGELEAPGEAGVETLVF-ASGMAAISSVLFSQLRAGDTAVLPD 119

Query: 751  DLYRKTRIYMETELPKRGITMTVIRPADMDALQDALDNNNVSLFFTETPTNPFLRCIDIE 930
            D Y+   + +  +L   GI +    P   DA  D LD     L + ETP+NP L   D+ 
Sbjct: 120  DGYQALPL-VRAQLEAYGIEVRTA-PTGRDAQLDVLDG--AKLLWIETPSNPGLDVCDVR 175

Query: 931  LVSNMCHNKGALLCIDSTFASPINQKALTLGADIVVHSATKYIAGHNDVIGGCISGRGE- 1107
             +    H  GAL+ +D+T A+P+ Q+ L LGAD  V S TK + GH DV+ G ++GR   
Sbjct: 176  RLVEAAHAGGALVAVDNTLATPLGQRPLELGADFSVASGTKQLTGHGDVLLGYVAGRDAG 235

Query: 1108 LVSKVRIYHHVVGGVLNPNASYLILRGMKTLHLRVQCQNNTALRMAQFLEEHPKIARVYY 1287
             ++ VR +  +VG +  P  ++L  R + TL LRV  Q++TAL++A+ L   P+I  + Y
Sbjct: 236  AMAAVRRWRKIVGAIPGPMEAWLAHRSIATLQLRVDRQDSTALKVAEALRTRPEITGLRY 295

Query: 1288 PGLPSHPEHHIAKSQMTGFGGVVSFEVDGDFDSTRRFIDSVKIPYHAPSFGGCESIIDQP 1467
            PGLP  P H +A  QM  +G VVSF +     +  RF+D++++   A SFGG  S     
Sbjct: 296  PGLPDDPSHKVASQQMLRYGCVVSFTLPSRARAD-RFLDALRLVEGATSFGGVRS----- 349

Query: 1468 AIMSYWDSKEQRDIYG---IKDNLIRFSIGVEDFGDLKNDIVQALDK 1599
                   + E+R  +G   + +  IR S+G ED  DL  D+++ALD+
Sbjct: 350  -------TAERRGRWGGDAVPEGFIRLSVGAEDPDDLVADLLRALDE 389



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>P50125:CYSD_EMENI O-acetylhomoserine - Emericella nidulans (Aspergillus nidulans)|
          Length = 437

 Score =  172 bits (437), Expect = 3e-42
 Identities = 125/422 (29%), Positives = 209/422 (49%), Gaps = 40/422 (9%)
 Frame = +1

Query: 445  SLAVHAGERLGRRIATDAITTPVVNTSAYWFSSSQE---LIDFKEGRHASFEYGRYGNPT 615
            +L +HAG+      AT++   P+  T++Y F+ S     L   KE  +    Y R  NPT
Sbjct: 11   TLQLHAGQEPDP--ATNSRAVPIYATTSYTFNDSAHGARLFGLKEFGNI---YSRIMNPT 65

Query: 616  TEALEKKMSALEKAESTVFVASGMYASVAMLSTLVPAGGHIVTTTDLYRKTRIYMETELP 795
             +  EK+++ALE   + V  +SG  A    +S L  AG +IV+T++LY  T    +   P
Sbjct: 66   VDVFEKRIAALEGGVAAVAASSGQAAQFMAISALAHAGDNIVSTSNLYGGTYNQFKVLFP 125

Query: 796  KRGITMTVIRPADMDALQDALDNNNVSLFFTETPTNPFLRCIDIELVSNMCHNKGALLCI 975
            + GIT   ++    + +  A+D+   ++ + ET  NP     D E+++ + H KG  L +
Sbjct: 126  RLGITTKFVQGDKAEDIAAAIDDRTKAV-YVETIGNPRYNVPDFEVIAKVAHEKGIPLVV 184

Query: 976  DSTF-ASPINQKALTLGADIVVHSATKYIAGHNDVIGGCI--SGR--------------- 1101
            D+TF A     + +  GADIVVHSATK+I GH   IGG +  SG+               
Sbjct: 185  DNTFGAGGYFVRPIEHGADIVVHSATKWIGGHGTTIGGVVVDSGKFDWGKNAARFPQFTQ 244

Query: 1102 --------------GELVSKVRIYHHV---VGGVLNPNASYLILRGMKTLHLRVQCQNNT 1230
                          G +   +R+   +   +G  LNP A+  ++ G++TL LR +   + 
Sbjct: 245  PSEGYHGLNFWETFGPIAFAIRVRVEILRDLGSALNPFAAQQLILGLETLSLRAERHASN 304

Query: 1231 ALRMAQFLEEHPKIARVYYPGLPSHPEHHIAKSQM-TGFGGVVSFEVDGDFDSTRRFIDS 1407
            AL +A +L+++  ++ V Y GL  H  H +AK  +  GFGGV+SF V G+     + +D+
Sbjct: 305  ALALANWLKKNDHVSWVSYVGLEEHSSHEVAKKYLKRGFGGVLSFGVKGEAAVGSQVVDN 364

Query: 1408 VKIPYHAPSFGGCESIIDQPAIMSYWDSKEQRDI-YGIKDNLIRFSIGVEDFGDLKNDIV 1584
             K+  +  + G  +++   P   ++    +Q  I  G+ ++ IR S+G E   D+  D  
Sbjct: 365  FKLISNLANVGDSKTLAIHPWSTTHEQLTDQERIDSGVTEDAIRISVGTEHIDDIIADFE 424

Query: 1585 QA 1590
            Q+
Sbjct: 425  QS 426



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>P06106:MET17_YEAST Protein MET17 [Includes: O-acetylhomoserine sulfhydrylase -|
            Saccharomyces cerevisiae (Baker's yeast)
          Length = 444

 Score =  167 bits (423), Expect = 1e-40
 Identities = 122/433 (28%), Positives = 208/433 (48%), Gaps = 47/433 (10%)
 Frame = +1

Query: 445  SLAVHAGERLGRRIATDAITTPVVNTSAYWFSSSQELIDFKEGRHASFEYGRYGNPTTEA 624
            ++ +HAG+      A  +   P+  T++Y F +S+            + Y R+ NPT+  
Sbjct: 7    TVQLHAGQENPGDNAHRSRAVPIYATTSYVFENSKHGSQLFGLEVPGYVYSRFQNPTSNV 66

Query: 625  LEKKMSALEKAESTVFVASGMYASVAMLSTLVPAGGHIVTTTDLYRKTRIYMETELPKRG 804
            LE++++ALE   + + V+SG  A    +  L   G +IV+T+ LY  T    +    + G
Sbjct: 67   LEERIAALEGGAAALAVSSGQAAQTLAIQGLAHTGDNIVSTSYLYGGTYNQFKISFKRFG 126

Query: 805  ITMTVIRPADMDALQDALDNNNVSLFFTETPTNPFLRCIDIELVSNMCHNKGALLCIDST 984
            I    +   + +  +   D    +++  ET  NP     D E +  + H  G  + +D+T
Sbjct: 127  IEARFVEGDNPEEFEKVFDERTKAVYL-ETIGNPKYNVPDFEKIVAIAHKHGIPVVVDNT 185

Query: 985  F-ASPINQKALTLGADIVVHSATKYIAGHNDVIGGCISGRGELVSK------------VR 1125
            F A     + +  GADIV HSATK+I GH   IGG I   G+   K              
Sbjct: 186  FGAGGYFCQPIKYGADIVTHSATKWIGGHGTTIGGIIVDSGKFPWKDYPEKFPQFSQPAE 245

Query: 1126 IYH---------------HV-------VGGVLNPNASYLILRGMKTLHLRVQCQNNTALR 1239
             YH               HV       +G ++NP AS+L+L+G++TL LR +     AL+
Sbjct: 246  GYHGTIYNEAYGNLAYIVHVRTELLRDLGPLMNPFASFLLLQGVETLSLRAERHGENALK 305

Query: 1240 MAQFLEEHPKIARVYYPGLPSHPEHHIAKSQMT-GFGGVVSFEV------DGDFD----S 1386
            +A++LE+ P ++ V YPGL SH  H  AK  ++ GFGGV+SF V      D + D    S
Sbjct: 306  LAKWLEQSPYVSWVSYPGLASHSHHENAKKYLSNGFGGVLSFGVKDLPNADKETDPFKLS 365

Query: 1387 TRRFIDSVKIPYHAPSFGGCESIIDQPAIMSYWDSKEQRDI-YGIKDNLIRFSIGVEDFG 1563
              + +D++K+  +  + G  ++++  P   ++    ++  +  G+  +LIR S+G+E   
Sbjct: 366  GAQVVDNLKLASNLANVGDAKTLVIAPYFTTHKQLNDKEKLASGVTKDLIRVSVGIEFID 425

Query: 1564 DLKNDIVQALDKI 1602
            D+  D  Q+ + +
Sbjct: 426  DIIADFQQSFETV 438



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>Q92441:MET17_KLULA Protein MET17 [Includes: O-acetylhomoserine sulfhydrylase -|
            Kluyveromyces lactis (Yeast) (Candida sphaerica)
          Length = 444

 Score =  159 bits (403), Expect = 3e-38
 Identities = 125/428 (29%), Positives = 200/428 (46%), Gaps = 50/428 (11%)
 Frame = +1

Query: 445  SLAVHAGERLGRRIATDAITTPVVNTSAYWFSSSQELIDFKEGRHASFEYGRYGNPTTEA 624
            +L +HAG+      A +    P+  T++Y F+ S+            + Y R  NPT + 
Sbjct: 7    TLQLHAGQEKTAD-AHNPRAVPIYATTSYVFNDSKHGAQLFGLETPGYIYSRIMNPTLDV 65

Query: 625  LEKKMSALEKAESTVFVASGMYASVAMLSTLVPAGGHIVTTTDLYRKTRIYMETELPKRG 804
            LEK+++ALE   + +  +SG  A    ++ L   G +IV+T+ LY  T    +    + G
Sbjct: 66   LEKRLAALEGGIAALATSSGQAAQTLAVTGLAHTGDNIVSTSFLYGGTYNQFKVAFKRLG 125

Query: 805  ITMTVI---RPADMDALQDALDNNNVSLFFTETPTNPFLRCIDIELVSNMCHNKGALLCI 975
            I    +   +P D + L D          + E+  NP     D E +  + H  G  + +
Sbjct: 126  IEARFVDGDKPEDFEKLFD----EKTKALYLESIGNPKYNVPDFEKIVAVAHKHGIPVVV 181

Query: 976  DSTF-ASPINQKALTLGADIVVHSATKYIAGHNDVIGGCISGRGELVSK----------- 1119
            D+TF A     + +  GADIV HSATK+I GH   +GG I   G+   K           
Sbjct: 182  DNTFGAGGFFCQPIKYGADIVTHSATKWIGGHGVTVGGVIIDSGKFPWKDYPEKFPQFSQ 241

Query: 1120 -VRIYH---------------HV-------VGGVLNPNASYLILRGMKTLHLRVQCQNNT 1230
                YH               HV       +G VL+P A +L+L+G++TL LR +   + 
Sbjct: 242  PSEGYHGLIFNDAFGPAAFIGHVRTELLRDLGPVLSPFAGFLLLQGLETLSLRGERHGSN 301

Query: 1231 ALRMAQFLEEHPKIARVYYPGLPSHPEHHIAKSQM-TGFGGVVSF----------EVDGD 1377
            AL++AQ+LE  P ++ V YPGLPSH  H  AK  +  GFGGV+SF          E D  
Sbjct: 302  ALKLAQYLESSPYVSWVSYPGLPSHSHHENAKKYLENGFGGVLSFGVKDLPNASEESDPF 361

Query: 1378 FDSTRRFIDSVKIPYHAPSFGGCESIIDQPAIMSYWD-SKEQRDIYGIKDNLIRFSIGVE 1554
              S  + +D++K+  +  + G  ++++  P   ++   + E++   G+  +LIR S+G E
Sbjct: 362  KASGAQVVDNLKLASNLANVGDSKTLVIAPYFTTHQQLTDEEKLASGVTKDLIRVSVGTE 421

Query: 1555 DFGDLKND 1578
               D+  D
Sbjct: 422  FIDDIIAD 429



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>P53101:STR3_YEAST Cystathionine beta-lyase - Saccharomyces cerevisiae (Baker's yeast)|
          Length = 465

 Score =  148 bits (373), Expect = 8e-35
 Identities = 111/371 (29%), Positives = 182/371 (49%), Gaps = 25/371 (6%)
 Frame = +1

Query: 556  IDFKEGRHASFEYGRYGNPTTEALEKKMSALEKA--ESTVFVASGMYASVAMLSTLVPAG 729
            +D       +++Y R GNPT   L+ ++  L +   E+ + V+SGM A   +L  LV   
Sbjct: 35   VDLNNEDAQNYDYSRSGNPTRSVLQHQIGKLYRVPQENVLAVSSGMTALDVILRGLVLLN 94

Query: 730  GH------IVTTTDLYRKTRIYMETELPKRGITMTVIRPADMDALQDALDN-NNVSLFFT 888
            G       I+   DLY  T+  +     +       +  +D +  +    + + V     
Sbjct: 95   GTDNHTPTIIAGDDLYGGTQRLLNFFKQQSHAVSVHVDTSDFEKFKTVFQSLDKVDCVLL 154

Query: 889  ETPTNPFLRCIDIELVSNM--CHNKGALLCIDSTFASPINQKALTL--GADIVVHSATKY 1056
            E+PTNP  + +DI  +     C +    + +D+T  S +N   L L  G D+V  SATKY
Sbjct: 155  ESPTNPLCKVVDIPRILRFVKCISPDTTVVVDNTMMSGLNCNPLQLNPGCDVVYESATKY 214

Query: 1057 IAGHNDVIGGCI-SGRGELVSKVRIYHHVVGGVLNPNASYLILRGMKTLHLRVQCQNNTA 1233
            + GH+D++GG I S   E+ SK+    +  G  L+P  S+L++RG+KTL +R+  Q   A
Sbjct: 215  LNGHHDLMGGVIISKTPEIASKLYFVINSTGAGLSPMDSWLLVRGLKTLGVRLYQQQRNA 274

Query: 1234 LRMAQFLEEH--------PKIARVYYPGLPSHPEHHIAKSQMTGFGGVVSFEVDGDFDST 1389
            + +A +LE           K  +  + GL S+P+  + KS   G G V+SFE  G F+ +
Sbjct: 275  MILAHWLENSCGFKPTRTNKATKTRFVGLRSNPDFKLHKSFNNGPGAVLSFET-GSFEHS 333

Query: 1390 RRFIDSVKIPYHA--PSFGGCESIIDQPAIMSYWD-SKEQRDIYGIKDNLIRFSIGVEDF 1560
            +R + S K+   A   SFG   S++  P  MS+     E R      ++L+R   G+E+ 
Sbjct: 334  KRLVSSKKLSIWAVTVSFGCVNSLLSMPCKMSHASIDPELRKERDFPEDLVRLCCGIENI 393

Query: 1561 GDLKNDIVQAL 1593
             DLK D++ A+
Sbjct: 394  VDLKKDLLAAM 404



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>Q07703:METC_BORAV Cystathionine beta-lyase - Bordetella avium|
          Length = 396

 Score =  143 bits (361), Expect = 2e-33
 Identities = 101/376 (26%), Positives = 178/376 (47%), Gaps = 9/376 (2%)
 Frame = +1

Query: 499  ITTPVVNTSAYWFSSSQELIDFKEGRHA---SFEYGRYGNPTTEALEKKMSALEKAESTV 669
            +  P V  S   F S  +L D +  + A   +  YGR G  T  ALE+  + LE      
Sbjct: 30   VNLPSVRASTVRFQSLAKLEDAQRRKAAGERASTYGRMGMDTHAALEQVFAELEGGTHCY 89

Query: 670  FVASGMYASVAMLSTLVPAGGHIVTTTDLYRKTRIYMETELPKRGITMTVIRPADMDALQ 849
              +SG+     +  +L+ AG H +     Y       E  L + GI +T     D  A  
Sbjct: 90   LASSGLAGISMVFLSLLSAGEHALVADCAYGPVHELHEAVLSRLGIDVTFF---DAKADL 146

Query: 850  DALDNNNVSLFFTETPTNPFLRCIDIELVSNMCHNKGALLCIDSTFASPINQKALTLGAD 1029
             +L      L F E P +     +D+  ++        +L  D+T+ S    + LTLGA 
Sbjct: 147  ASLVRPTTRLIFAEAPGSLLFEMLDMPALARFAKQHDLILATDNTWGSGYIYRPLTLGAQ 206

Query: 1030 IVVHSATKYIAGHNDVIGGCISGRGELVSK-VRIYHHVVGGVLNPNASYLILRGMKTLHL 1206
            + V + TKY+ GH+D++ G +    E ++K +    + +G  ++ + ++L LRG++T+ +
Sbjct: 207  VSVIAGTKYVGGHSDLMLGAVVTNDEAIAKRLNRTQYALGYSVSADDAWLALRGVRTMPV 266

Query: 1207 RVQCQNNTALRMAQFLEEHPKIARVYYPGLPSHPEHHIAKSQMTGFGGVVSFEVDGDFDS 1386
            R+      AL + +FL+  P++ R+Y+P  P+ P H + +   +G  G+++ ++     +
Sbjct: 267  RMAQHARHALEVCEFLQNRPEVVRLYHPAWPADPGHALWQRDCSGSNGMLAVQLGLSPQA 326

Query: 1387 TRRFIDSVKIPYHAPSFGGCESIID-----QPAIMSYWDSKEQRDIYGIKDNLIRFSIGV 1551
             R F++++ +     S+GG ES++      + A   YW         G  D L+R  IG+
Sbjct: 327  ARDFVNALTLFGIGFSWGGFESLVQLVTPGELARHQYWQ--------GGSDALVRLHIGL 378

Query: 1552 EDFGDLKNDIVQALDK 1599
            E   DL  D+ QALD+
Sbjct: 379  ESPADLIADLAQALDR 394



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>P06721:METC_ECOLI Cystathionine beta-lyase - Escherichia coli|
          Length = 395

 Score =  140 bits (353), Expect = 2e-32
 Identities = 102/383 (26%), Positives = 186/383 (48%), Gaps = 7/383 (1%)
 Frame = +1

Query: 454  VHAGERLGRRIATDAITTPVVNTSAYWFSSSQELIDFKEGR-HASFEYGRYGNPTTEALE 630
            V+AG    ++    A+ + +   S+  F S +        R +    YGR G  T  +L+
Sbjct: 11   VNAGR--SKKYTLGAVNSVIQRASSLVFDSVEAKKHATRNRANGELFYGRRGTLTHFSLQ 68

Query: 631  KKMSALEKAESTVFVASGMYASVAMLSTLVPAGGHIVTTTDLYRKTRIYMETELPKRGIT 810
            + M  LE     V    G  A    +   +  G H++ T   Y  ++ +    L K G+T
Sbjct: 69   QAMCELEGGAGCVLFPCGAAAVANSILAFIEQGDHVLMTNTAYEPSQDFCSKILSKLGVT 128

Query: 811  MTVIRPADMDALQDALDNNNVSLFFTETPTNPFLRCIDIELVSNMCHN--KGALLCIDST 984
             +   P     +   L  N   + F E+P +  +   D+  +     +    A++ ID+T
Sbjct: 129  TSWFDPLIGADIVKHLQPNT-KIVFLESPGSITMEVHDVPAIVAAVRSVVPDAIIMIDNT 187

Query: 985  FASPINQKALTLGADIVVHSATKYIAGHNDVIGGCISGRGELVSKVRIYHHVVGGVLNPN 1164
            +A+ +  KAL  G D+ + +ATKY+ GH+D + G          ++R   +++G +++ +
Sbjct: 188  WAAGVLFKALDFGIDVSIQAATKYLVGHSDAMIGTAVCNARCWEQLRENAYLMGQMVDAD 247

Query: 1165 ASYLILRGMKTLHLRVQCQNNTALRMAQFLEEHPKIARVYYPGLPSHPEHHIAKSQMTGF 1344
             +Y+  RG++TL +R++  + ++L++A++L EHP++ARV +P LP    H   K   TG 
Sbjct: 248  TAYITSRGLRTLGVRLRQHHESSLKVAEWLAEHPQVARVNHPALPGSKGHEFWKRDFTGS 307

Query: 1345 GGVVSFEVDGDFDSTR--RFIDSVKIPYHAPSFGGCESII--DQPAIMSYWDSKEQRDIY 1512
             G+ SF +    ++     ++D+  +   A S+GG ES+I  +QP  ++    + + D  
Sbjct: 308  SGLFSFVLKKKLNNEELANYLDNFSLFSMAYSWGGYESLILANQPEHIAAIRPQGEIDFS 367

Query: 1513 GIKDNLIRFSIGVEDFGDLKNDI 1581
            G    LIR  IG+ED  DL  D+
Sbjct: 368  G---TLIRLHIGLEDVDDLIADL 387



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>P44527:METC_HAEIN Cystathionine beta-lyase - Haemophilus influenzae|
          Length = 396

 Score =  140 bits (352), Expect = 2e-32
 Identities = 99/394 (25%), Positives = 194/394 (49%), Gaps = 7/394 (1%)
 Frame = +1

Query: 442  ASLAVHAGERLGRRIATDAITTPVVNTSAYWFSSSQELIDFKEGR-HASFEYGRYGNPTT 618
            +++ +H+G +  +R +  ++   +   S+  F S ++     + R      YGR G  T 
Sbjct: 8    STMFIHSGRQ--KRFSQGSVNPVLQRASSLLFDSIEDKKHATQRRAKGELFYGRRGTLTH 65

Query: 619  EALEKKMSALEKAESTVFVASGMYASVAMLSTLVPAGGHIVTTTDLYRKTRIYMETELPK 798
             AL+  M  +E          G  A    + + V  G H++ +   Y  T+ +    L K
Sbjct: 66   FALQDLMCEMEGGAGCYLYPCGTAAVTNSILSFVKTGDHVLMSGAAYEPTQYFCNIVLKK 125

Query: 799  RGITMTVIRPADMDALQDALDNNNVSLFFTETPTNPFLRCIDIELVSNMCH--NKGALLC 972
              I +T   P   + +   L   N  + F E P++  +   DI  +       N   ++ 
Sbjct: 126  MQIDITYYDPLIGEDIA-TLIQPNTKVLFLEAPSSITMEIPDIPTIVKAARKVNPNIVIM 184

Query: 973  IDSTFASPINQKALTLGADIVVHSATKYIAGHNDVIGGCISGRGELVSKVRIYHHVVGGV 1152
            ID+T+++ +  KAL    DI + + TKY+ GH+D++ G          ++R + +++G +
Sbjct: 185  IDNTWSAGVLFKALEHDIDISIQAGTKYLVGHSDIMIGTAVANARTWDQLREHSYLMGQM 244

Query: 1153 LNPNASYLILRGMKTLHLRVQCQNNTALRMAQFLEEHPKIARVYYPGLPSHPEHHIAKSQ 1332
            ++ +++Y   RG++TL +R++    +++++A++L E P++  VY+P LPS P H      
Sbjct: 245  VDADSAYTTARGIRTLGVRLKQHQESSIKVAKWLSEQPEVKTVYHPALPSCPGHEFFLRD 304

Query: 1333 MTGFGGVVSFEVDGDFDSTR--RFIDSVKIPYHAPSFGGCESII--DQPAIMSYWDSKEQ 1500
             +G  G+ SFE+     S +  +F+D  ++   A S+GG ES+I  +QP  +++     +
Sbjct: 305  FSGSSGLFSFELTQRLTSEQVSKFMDHFQLFAMAYSWGGFESLILCNQPEEIAHIRPNIK 364

Query: 1501 RDIYGIKDNLIRFSIGVEDFGDLKNDIVQALDKI 1602
            R++ G   +LIR  IG E+  +L  D+    ++I
Sbjct: 365  RNLTG---SLIRVHIGFENVDELIADLKAGFERI 395



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>P18949:METC_SALTY Cystathionine beta-lyase - Salmonella typhimurium|
          Length = 395

 Score =  129 bits (324), Expect = 4e-29
 Identities = 96/344 (27%), Positives = 161/344 (46%), Gaps = 7/344 (2%)
 Frame = +1

Query: 592  YGRYGNPTTEALEKKMSALEKAESTVFVASGMYASVAMLSTLVPAGGHIVTTTDLYRKTR 771
            YGR G  T  +L++ M  LE          G  A    +   V  G HI+ T   Y  ++
Sbjct: 56   YGRRGTLTHFSLQEAMCELEGGAGCALFPCGAAAVANTILAFVEQGDHILMTNTAYEPSQ 115

Query: 772  IYMETELPKRGITMTVIRPA-DMDALQDALDNNNVSLFFTETPTNPFLRCIDIELVSNMC 948
             +    L K G+T +   P    D  Q    N  V   F E+P +  +   DI  + +  
Sbjct: 116  DFCSKILGKLGVTTSWFDPLIGADITQHIQPNTKV--VFLESPGSITMEVHDIPSIVSAV 173

Query: 949  HNKG--ALLCIDSTFASPINQKALTLGADIVVHSATKYIAGHNDVIGGCISGRGELVSKV 1122
                  A++ ID+T+A+ +  KAL    DI + + TKY+ GH+D + G          ++
Sbjct: 174  RRVAPEAVIMIDNTWAAGVLFKALEFDIDISIQAGTKYLIGHSDAMVGTAVANARCWEQL 233

Query: 1123 RIYHHVVGGVLNPNASYLILRGMKTLHLRVQCQNNTALRMAQFLEEHPKIARVYYPGLPS 1302
            R   +++G +L+ + +Y+  RG++TL +R++    ++L++A +L  HP++ARV +P LP 
Sbjct: 234  RENAYLMGQMLDADTAYMTSRGLRTLGVRLRQHQESSLKIAAWLANHPQVARVNHPALPG 293

Query: 1303 HPEHHIAKSQMTGFGGVVSFEVDGDFDSTR--RFIDSVKIPYHAPSFGGCESII--DQPA 1470
               H   K   TG  G+ SF ++          ++D+  +   A S+GG ES+I  +QP 
Sbjct: 294  SKGHAFWKRDFTGSSGLFSFVLNKKLTEAELSAYLDNFSLFSMAYSWGGYESLIIANQPE 353

Query: 1471 IMSYWDSKEQRDIYGIKDNLIRFSIGVEDFGDLKNDIVQALDKI 1602
             ++        D  G    L+R  IG+E   DL  D+     +I
Sbjct: 354  QIAAIRPAGGVDFTG---TLVRVHIGLESVDDLIADLAAGFARI 394



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>P38716:YHR2_YEAST Uncharacterized trans-sulfuration enzyme YHR112C - Saccharomyces|
            cerevisiae (Baker's yeast)
          Length = 378

 Score =  127 bits (319), Expect = 2e-28
 Identities = 110/402 (27%), Positives = 182/402 (45%), Gaps = 14/402 (3%)
 Frame = +1

Query: 439  DASLAVHAGERLGRRIATDAITTPVVNTSAYWFSSSQELIDFKEGRHASFE-----YGRY 603
            D S A+  G+    R+   A   P +N S  +     +LI + E  +  F      Y R 
Sbjct: 3    DLSTALIHGDDKDNRVTDVA---PPINVSTTFRYDDDDLIPWTERENLDFMEKKPVYSRL 59

Query: 604  GNPTTEALEKKMSALEKAESTVFVASGMYASVAMLSTLVPAGGHIVTTTDLYRKTRIYME 783
             +P +  LE   S +    + ++ +SG+ A  A +    P    I  +   Y   R    
Sbjct: 60   AHPNSTRLESIFSEILDGYAVIY-SSGLAAFYAAMVHYNPKKIFIGQS---YHGVRAIAN 115

Query: 784  TELPKRGITMTVIRPADMDALQDALDNNNVSLFFTETPTNPFLRCIDIELVSNMCHNKGA 963
                  GI    +   +  A +         +   E+P NP+    DIE ++   H KGA
Sbjct: 116  ILTRNYGIEQHPLEDIEKCASEG-------DIVHLESPVNPYGTSSDIESLARRAHAKGA 168

Query: 964  LLCIDSTFASPINQKALTLGADIVVHSATKYIAGHNDVIGGCISGRGELVSKV----RIY 1131
            LL +DSTFASP  Q A   GADIV++SATKY  GH+D++ G +  + E  S+     RIY
Sbjct: 169  LLIVDSTFASPPLQYAWNFGADIVLYSATKYFGGHSDLLSGVLVVKEEATSRQLKDDRIY 228

Query: 1132 HHVVGGVLNPNASYLILRGMKTLHLRVQCQNNTALRMAQFLEEHPK-----IARVYYPGL 1296
               +G  +    S+++LR ++T  +R+  Q+  A ++ +FL +H       +  +Y+  L
Sbjct: 229  ---LGTNVANLESFMLLRSLRTYEMRITKQSENATKLVRFLSDHQSEFDKVLKTIYHSSL 285

Query: 1297 PSHPEHHIAKSQMTGFGGVVSFEVDGDFDSTRRFIDSVKIPYHAPSFGGCESIIDQPAIM 1476
             +  E  + K  + G+G V +  +    +  ++    +K  +HA S GG ES+++  A+ 
Sbjct: 286  QT--EEFVKKQLVGGYGPVFAITLYTK-EQCKQLPLKLKYFHHATSLGGIESLVEWRAMT 342

Query: 1477 SYWDSKEQRDIYGIKDNLIRFSIGVEDFGDLKNDIVQALDKI 1602
              +          I   LIR S+G E   DL  D+  AL ++
Sbjct: 343  DPY----------IDQTLIRVSVGCESANDLIKDLASALKEL 374



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>O42851:YFHE_SCHPO Uncharacterized trans-sulfuration enzyme C23A1.14c -|
            Schizosaccharomyces pombe (Fission yeast)
          Length = 398

 Score =  124 bits (311), Expect = 1e-27
 Identities = 105/354 (29%), Positives = 160/354 (45%), Gaps = 24/354 (6%)
 Frame = +1

Query: 592  YGRYGNPTTEALEKKMSALEKAESTVFVASGMYASVAMLSTLVPA---------GGHIVT 744
            Y R      +  E  +S++  A S V+ +SG+ A   +LS L P          GG+  T
Sbjct: 66   YARISGNNVDRAEASLSSVLGAPSVVY-SSGLAAIYGLLSYLNPKHIAVHKPGFGGYSGT 124

Query: 745  TTDLYRKTRIYMETELPKRGITMTVIRPADMDALQDALDNNNVSLFFTETPTNPFLRCID 924
               + R  R+             T +  + +D   DA+   +V   + ETP NP     D
Sbjct: 125  IQIIARINRL-------------TGLETSFIDGKCDAIGEGDV--IWLETPLNPLGIAFD 169

Query: 925  IELVSNMCHNKGALLCIDSTFASPINQKALTLGADIVVHSATKYIAGHNDVIGGCISGRG 1104
            I     +   KGA+L +DSTFA P  Q AL LGAD VVHSATKY+AGH+DV+ G  + + 
Sbjct: 170  IPFYKELAKKKGAILVVDSTFAPPPIQDALVLGADYVVHSATKYLAGHSDVLAGVTASKD 229

Query: 1105 -ELVSKVRIYHHVVGGVLNPNASYLILRGMKTLHLRVQCQNNTALRMAQFLE-------- 1257
               +  ++     +G +L+P  ++L+LR ++T  LR+   +     +AQ L         
Sbjct: 230  RSKILDLKADRAYLGTILHPQQAFLLLRSLRTFPLRIAKHSENGFLVAQHLNKLATDEQF 289

Query: 1258 ------EHPKIARVYYPGLPSHPEHHIAKSQMTGFGGVVSFEVDGDFDSTRRFIDSVKIP 1419
                  +   I  VY+  L +  +  +AK+   G     S  +  D    +     +K  
Sbjct: 290  ATSLGIDSSLILEVYHNSLQT--KEFVAKNLTGGHASCFSVLLKSD-TVAKHLCCELKYF 346

Query: 1420 YHAPSFGGCESIIDQPAIMSYWDSKEQRDIYGIKDNLIRFSIGVEDFGDLKNDI 1581
            +HA S G  ES+I+   +    DSK       I   L+R SIG+ED  DL  D+
Sbjct: 347  HHATSLGSVESLIEWRRMT---DSK-------IDPRLVRLSIGIEDAADLIADL 390



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>P43623:METC_YEAST Putative cystathionine beta-lyase - Saccharomyces cerevisiae (Baker's|
            yeast)
          Length = 340

 Score =  114 bits (285), Expect = 1e-24
 Identities = 80/286 (27%), Positives = 132/286 (46%), Gaps = 2/286 (0%)
 Frame = +1

Query: 592  YGRYGNPTTEALEKKMSALEKAESTVFVASGMYASVAMLSTLVPAGGHIVTTTDLYRKTR 771
            YG  G+PT + LE   + L     TV  ASG+ +    L  L  AG HI+ T  +Y  TR
Sbjct: 56   YGTAGSPTIDNLENAWTHLTGGAGTVLSASGLGSISLALLALSKAGDHILMTDSVYVPTR 115

Query: 772  IYMETELPKRGITMTVIRPADMDALQDALDNNNVSLFFTETPTNPFLRCIDIELVSNMCH 951
            +  +  L K G+      P+    ++  L   N ++ F E+P +  +   DI  + ++  
Sbjct: 116  MLCDGLLAKFGVETDYYDPSIGKDIEK-LVKPNTTVIFLESPGSGTMEVQDIPALVSVAK 174

Query: 952  NKGALLCIDSTFASPINQKALTLGADIVVHSATKYIAGHNDVIGGCISGRGELVSKVRIY 1131
              G    +D+T+A+P+   A   G DI V + TKY+ GH+D++ G  S   E    +R  
Sbjct: 175  KHGIKTILDNTWATPLFFDAHAHGIDISVEAGTKYLGGHSDLLIGLASANEECWPLLRST 234

Query: 1132 HHVVGGVLNPNASYLILRGMKTLHLRVQCQNNTALRMAQFLEEHPKIARVYYPGLPSHPE 1311
            +  +  +       L LRGM+TLHLR++     AL +A +L    ++ +V +P     P 
Sbjct: 235  YDAMAMLPGAEDCQLALRGMRTLHLRLKEVERKALDLAAWLGNRDEVEKVLHPAFEDCPG 294

Query: 1312 HHIAKSQMTGFGGVVSFEVDGDFD--STRRFIDSVKIPYHAPSFGG 1443
            H        G  G+ S  +   F      + ++ +K+     S+GG
Sbjct: 295  HEYWVRDYKGSSGLFSIVLKNGFTRAGLEKMVEGMKVLQLGFSWGG 340



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>O74314:MET7_SCHPO Probable cystathionine gamma-synthase - Schizosaccharomyces pombe|
            (Fission yeast)
          Length = 610

 Score = 90.1 bits (222), Expect = 3e-17
 Identities = 69/258 (26%), Positives = 125/258 (48%), Gaps = 5/258 (1%)
 Frame = +1

Query: 835  MDALQDALDNNN-VSLFFTETPTNPFLRCIDIELVSNMCHNKGALLCIDSTFASPINQKA 1011
            +D  +  L++   V   F E P+NP L   D+  +  +  +    + +D T  + +N + 
Sbjct: 355  LDEFEKRLESGEKVMALFCEFPSNPLLNSPDLVRIRKLADSYDFAVVVDETIGNFVNVEV 414

Query: 1012 LTLGADIVVHSATKYIAGHNDVIGGC--ISGRGELVSKVR-IYHHVVGGVLNPNASYLIL 1182
            L L AD+VV S TK  +G ++V+GG   ++      S+++     +   +L    +  + 
Sbjct: 415  LPL-ADVVVSSLTKIFSGDSNVMGGSMVLNPSSRYYSRIKDAMKALYEDLLYDEDALTLE 473

Query: 1183 RGMKTLHLRVQCQNNTALRMAQFLEEHPKIARVYYPGLPSHPEHHIA-KSQMTGFGGVVS 1359
            R  +    R Q  N+ A  +   L ++PKI  +YYP   +  EH  A + +  G+GG++S
Sbjct: 474  RNSRDFAERSQVINHNAETICNLLYQNPKIKTLYYPKYNTSKEHFEACRRENGGYGGLLS 533

Query: 1360 FEVDGDFDSTRRFIDSVKIPYHAPSFGGCESIIDQPAIMSYWDSKEQRDIYGIKDNLIRF 1539
                   D+ R+F D +++    PS G   ++    AI++++   +     GI  NL+R 
Sbjct: 534  VVFHNPEDA-RQFYDKIQVA-KGPSLGTNFTLASPYAILAHYQELDWAGENGIDRNLVRV 591

Query: 1540 SIGVEDFGDLKNDIVQAL 1593
            S+G+E    LKN  + AL
Sbjct: 592  SVGMEPSEHLKNVFINAL 609



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>P38675:MET7_NEUCR Cystathionine gamma-synthase - Neurospora crassa|
          Length = 542

 Score = 84.7 bits (208), Expect = 1e-15
 Identities = 67/265 (25%), Positives = 118/265 (44%), Gaps = 10/265 (3%)
 Frame = +1

Query: 829  ADMDALQDALDNNNVSL-FFTETPTNPFLRCIDIELVSNMCHNKGALLCIDSTFASPINQ 1005
            +D+D L+  L++    L  F E P NP L C D+  +  +       + +D T  +  N 
Sbjct: 276  SDLDDLETRLESGERYLALFCEFPGNPLLTCPDLVRIRELADKYEFAVVVDETIGTFANV 335

Query: 1006 KALTLGADIVVHSATKYIAGHNDVIGGCISGRGELVSKVRIYHHVVGGVLN--------P 1161
              L   ADIVV S TK  +G  +V+GG     G + +    Y+  +   +         P
Sbjct: 336  NVLQF-ADIVVSSLTKIFSGDCNVMGG-----GAIFNPNSRYYSALKSFVQQQLEDTYWP 389

Query: 1162 NASYLILRGMKTLHLRVQCQNNTALRMAQFLEEHPKIARVYYPGL-PSHPEHHIAKSQMT 1338
                 + R  +    R+   N  A  + + L++HP +  +YYP    S   +   K    
Sbjct: 390  EDVIFMERNSRDFVARIDRVNANAEAICRVLQDHPLVKTLYYPKYNDSRANYEAVKLPQG 449

Query: 1339 GFGGVVSFEVDGDFDSTRRFIDSVKIPYHAPSFGGCESIIDQPAIMSYWDSKEQRDIYGI 1518
            G+GG++S  + G   +   F D+++     PS G   ++     +++++   +  + YG+
Sbjct: 450  GYGGLISVVLKGKKQAVA-FYDAIETA-KGPSLGTNFTLTSPYVLLAHYQELDWAEQYGV 507

Query: 1519 KDNLIRFSIGVEDFGDLKNDIVQAL 1593
              NLIR S+G+E   +L N   +AL
Sbjct: 508  DRNLIRISVGLEGTDELINVFTRAL 532



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>P47164:MET7_YEAST Cystathionine gamma-synthase - Saccharomyces cerevisiae (Baker's|
            yeast)
          Length = 639

 Score = 70.9 bits (172), Expect = 2e-11
 Identities = 65/268 (24%), Positives = 126/268 (47%), Gaps = 13/268 (4%)
 Frame = +1

Query: 835  MDALQDALDNNNVSL-FFTETPTNPFLRCIDIELVSNMCHNKGALLCIDSTFASPINQKA 1011
            M+AL++ L +    L  F E P+NP L+  D++ +  +       + +D T    +N   
Sbjct: 371  MNALKNILHSGEQILAVFIEAPSNPLLKMGDLQELKRLSDLYSFYIVVDETVGGFVNIDV 430

Query: 1012 LTLGADIVVHSATKYIAGHNDVIGGCI--SGRGELVSKVRIYHHVVGGVLN----PNASY 1173
            L   ADIV  S TK  +G ++VI G +  + RG++    R +     G  +     +A  
Sbjct: 431  LPY-ADIVCSSLTKIFSGDSNVIAGSLVLNPRGKIYEFARKFMKTEDGYEDCLWCEDALC 489

Query: 1174 LILRGMKTLHLRVQCQNNTALRMAQFL--EEHPKIARVYYPGLPSHPEHHIAKSQMT--- 1338
            L       +   ++   NT + + + L  +      ++YYP L S        S M+   
Sbjct: 490  LERNSRDFVERTIKVNTNTDILLKRVLLPQVGKLFKKIYYPSLTSEDTKRNYDSVMSTKD 549

Query: 1339 -GFGGVVSFEVDGDFDSTRRFIDSVKIPYHAPSFGGCESIIDQPAIMSYWDSKEQRDIYG 1515
             G+GG+ S     + +  ++F +++++    PS G   ++    AI++++   ++   YG
Sbjct: 550  GGYGGLFSLTFF-NIEEAKKFFNNLEL-CKGPSLGTNFTLACPYAIIAHYQELDEVAQYG 607

Query: 1516 IKDNLIRFSIGVEDFGDLKNDIVQALDK 1599
            ++ NL+R S+G+E+   L N   +A++K
Sbjct: 608  VETNLVRVSVGLENSDVLCNVFQRAIEK 635



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>Q04533:METX_YEAST Putative cystathionine gamma-synthase YML082W - Saccharomyces|
            cerevisiae (Baker's yeast)
          Length = 649

 Score = 68.9 bits (167), Expect = 6e-11
 Identities = 65/253 (25%), Positives = 111/253 (43%), Gaps = 14/253 (5%)
 Frame = +1

Query: 883  FTETPTNPFLRCIDIELVSNMCHNKGALLCIDSTFASPINQKALTLGADIVVHSATKYIA 1062
            F ETP+NP L+  ++  +  +    G  + ID T    +N   L   ADIV  S TK  +
Sbjct: 396  FIETPSNPLLKMGNLLELKRLSELFGFFIIIDETVGGIVNIDGLPF-ADIVCSSLTKTFS 454

Query: 1063 GHNDVIGGCI-----SGRGELVSKVRIYHHVVGGVL-NPNASYLILRGMKTLHLRVQCQN 1224
            G ++VIGG +     S   E  S+          +L   +A YL       +   ++   
Sbjct: 455  GDSNVIGGSMVLNPQSRVYEFASRFMQLEDEYEDLLWCEDAIYLERNSRDFIARTIRINY 514

Query: 1225 NTALRMAQFLEEH----PKIARVYYPGLPSHPE----HHIAKSQMTGFGGVVSFEVDGDF 1380
            +T   + + L+ H        ++YYP L S         +   +  G+GG+ S     D 
Sbjct: 515  STEYLLDKILKPHVGENKLFKKIYYPNLTSKETLTNYDMVRCKKEGGYGGLFSLTFH-DE 573

Query: 1381 DSTRRFIDSVKIPYHAPSFGGCESIIDQPAIMSYWDSKEQRDIYGIKDNLIRFSIGVEDF 1560
            D    F D++K+    PS G   ++     +M+Y+   +  + +G++ NL+R S+G+E  
Sbjct: 574  DHAAAFYDNLKLN-KGPSLGTNFTLAFPYTLMTYYHELDMAEKFGVERNLLRISVGLESQ 632

Query: 1561 GDLKNDIVQALDK 1599
              L     +A+DK
Sbjct: 633  SILGKIFQEAIDK 645



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>Q12198:METW_YEAST Putative cystathionine gamma-synthase YLL058W - Saccharomyces|
            cerevisiae (Baker's yeast)
          Length = 575

 Score = 65.5 bits (158), Expect = 7e-10
 Identities = 70/271 (25%), Positives = 123/271 (45%), Gaps = 14/271 (5%)
 Frame = +1

Query: 832  DMDALQDALDNNNVSLF--FTETPTNPFLRCIDIELVSNMCHNKGALLCIDSTFASPINQ 1005
            D+  LQ  L+ +   +   F ETP+NP L   D++ + ++    G  + ID T    +N 
Sbjct: 303  DVVELQKFLETSKQRILAVFVETPSNPLLNMPDLKKLRSLADQYGFFIVIDDTIGG-LNV 361

Query: 1006 KALTLGADIVVHSATKYIAGHNDVIGGCI--SGRGELVSKVRIYHHVVG--GVLNPNASY 1173
              L   ADIV  S TK   G ++V+GG +  + +  L    R Y        +L    + 
Sbjct: 362  DILPY-ADIVSTSLTKLFNGASNVMGGSVVLNPKSSLYPYAREYFRSANFEDLLWCEDAI 420

Query: 1174 LILRGMKTLHLR-VQCQNNTALRMAQFL--EEHPKIARVYYPGLPS---HPEHHIAKSQM 1335
            ++ R  +    R ++   NT + +   L  EE     ++YYP + S      +   +++ 
Sbjct: 421  VLERNSRDFEDRTLRANANTGILLNDLLLPEEGKICKKIYYPTVTSKETFENYESVRNER 480

Query: 1336 TGFGGV--VSFEVDGDFDSTRRFIDSVKIPYHAPSFGGCESIIDQPAIMSYWDSKEQRDI 1509
             G+G +  V+F  +GD    + F DS+K+ +  PS G   ++      +++    E+   
Sbjct: 481  GGYGCLFSVAFFNEGD---AKAFYDSLKV-FKGPSNGTNFTLACPYVHLAHHSELEEVSK 536

Query: 1510 YGIKDNLIRFSIGVEDFGDLKNDIVQALDKI 1602
            +G   N+IR S+G+ED   L      ALD +
Sbjct: 537  FGADPNIIRVSVGLEDIQWLLKVFSSALDVV 567



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>Q57622:Y158_METJA UPF0425 pyridoxal phosphate-dependent protein MJ0158 - Methanococcus|
            jannaschii
          Length = 374

 Score = 42.4 bits (98), Expect = 0.006
 Identities = 47/170 (27%), Positives = 74/170 (43%), Gaps = 13/170 (7%)
 Frame = +1

Query: 736  IVTTTDLYRKTRIYMETELP-----KRGITMTVIRPADMDALQDALDNNNVSLFFTETPT 900
            + T   L  K  I+   ELP     +R   +   +  + D + + L+  +       T +
Sbjct: 90   LATILALKPKKVIHYLPELPGHPSIERSCKIVNAKYFESDKVGEILNKIDKDTLVIITGS 149

Query: 901  NPFLRCIDIE---LVSNMCHNKGALLCIDSTFASPI----NQK-ALTLGADIVVHSATKY 1056
               L+ I++E    V N   NK A++ +D    + +    NQ  AL LGAD+VV S  K 
Sbjct: 150  TMDLKVIELENFKKVINTAKNKEAIVFVDDASGARVRLLFNQPPALKLGADLVVTSTDKL 209

Query: 1057 IAGHNDVIGGCISGRGELVSKVRIYHHVVGGVLNPNASYLILRGMKTLHL 1206
            + G     GG ++G+ ELV K+ I     G    P     I R +K  +L
Sbjct: 210  MEGPR---GGLLAGKKELVDKIYIEGTKFGLEAQPPLLAGIYRALKNFNL 256



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>O27936:Y1914_METTH UPF0425 pyridoxal phosphate-dependent protein MTH_1914 -|
            Methanobacterium thermoautotrophicum
          Length = 377

 Score = 34.7 bits (78), Expect = 1.3
 Identities = 24/97 (24%), Positives = 45/97 (46%), Gaps = 6/97 (6%)
 Frame = +1

Query: 922  DIELVSNMCHNKGALLCIDSTFASPIN------QKALTLGADIVVHSATKYIAGHNDVIG 1083
            D+  V  + H+ G  + +D    + +       ++A  LGAD+ V S  K + G     G
Sbjct: 158  DLVRVIEIAHDAGIPVLVDDASGARLRTVLYGQRRACDLGADLAVTSTDKLMHGPR---G 214

Query: 1084 GCISGRGELVSKVRIYHHVVGGVLNPNASYLILRGMK 1194
            G ++GR EL+ +V+   +  G    P     ++R ++
Sbjct: 215  GLMAGRAELIERVKSKAYQFGLEAQPPLVAAMVRALE 251



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>Q818M4:GCSPA_BACCR Probable glycine dehydrogenase [decarboxylating] subunit 1 - Bacillus|
            cereus (strain ATCC 14579 / DSM 31)
          Length = 447

 Score = 33.9 bits (76), Expect = 2.3
 Identities = 33/149 (22%), Positives = 70/149 (46%), Gaps = 8/149 (5%)
 Frame = +1

Query: 634  KMSALEKAESTVFVASGMYASVAMLSTLVPAGGHIVTTTDLYRKTRIYMETELPKRGITM 813
            +++ ++ A S+++      A  AML+        I+ ++ ++ ++R  +ET    + + +
Sbjct: 124  ELTGMDVANSSMYDGGTALAEAAMLAAGHTRKKKILVSSAVHPESRAVLETYAKGQNLEV 183

Query: 814  TVIR----PADMDALQDALDNNNVSLFFTETPTNPFLRCIDIELVSNMCHNKGALLCIDS 981
              I       D+D LQ  +D + V+    + P N F +   +  +  + H + +L  + S
Sbjct: 184  VEINHKDGVTDLDVLQSEVD-DTVACVIVQYP-NFFGQVEKLADIEKIVHQQKSLFIVSS 241

Query: 982  TFASPINQKALT----LGADIVVHSATKY 1056
               +P++  ALT     GADIV+  A  +
Sbjct: 242  ---NPLSLGALTPPGKFGADIVIGDAQPF 267



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>Q9HPK0:GCSPB_HALSA Probable glycine dehydrogenase [decarboxylating] subunit 2 -|
            Halobacterium salinarium (Halobacterium halobium)
          Length = 473

 Score = 33.5 bits (75), Expect = 3.0
 Identities = 26/79 (32%), Positives = 38/79 (48%), Gaps = 2/79 (2%)
 Frame = +1

Query: 832  DMDALQDALDNNNVSLFFTETPTNPFLRCIDIELVSNMCHNKGALLCIDSTFASPINQKA 1011
            D+DAL+ AL  N  +L  T  P    L   DIE ++ M H+ G LL  D    + +  +A
Sbjct: 196  DLDALEAALGENTAALMLTN-PNTLGLFERDIEPIAEMVHDAGGLLYYDGANLNALLGRA 254

Query: 1012 L--TLGADIVVHSATKYIA 1062
                +G DI+  +  K  A
Sbjct: 255  RPGDMGFDIMHFNVHKTFA 273



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>P25070:TCH2_ARATH Calmodulin-related protein 2, touch-induced - Arabidopsis thaliana|
            (Mouse-ear cress)
          Length = 161

 Score = 33.1 bits (74), Expect = 3.9
 Identities = 18/48 (37%), Positives = 29/48 (60%), Gaps = 1/48 (2%)
 Frame = -3

Query: 1035 NNVST*SQCF-LIDWGGKGAINAKQCSLVMAHIGDKLNINASEKWISR 895
            N+VS   + F L D  G G I+AK+   VM ++G+K ++   +K IS+
Sbjct: 90   NDVSDLKEAFELYDLDGNGRISAKELHSVMKNLGEKCSVQDCKKMISK 137



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>Q7TQM5:KPRP_RAT Keratinocyte proline-rich protein - Rattus norvegicus (Rat)|
          Length = 699

 Score = 32.7 bits (73), Expect = 5.1
 Identities = 25/83 (30%), Positives = 32/83 (38%), Gaps = 9/83 (10%)
 Frame = +3

Query: 1113 LQGPHLSP------CSWWCSKPECFLSDPPGHENTASPC---SMPE*YCSTDGPVFRGTS 1265
            + G H SP      CS  C  P+C +         +SPC    +P   C    P  RG S
Sbjct: 345  IYGSHCSPRGRPSGCSQRCG-PKCRIE-------ISSPCCPRQVPPQRCPVQIPPIRGRS 396

Query: 1266 KDCTCILSWLAKSPRTSHCQEPN 1334
            + C    SW    P    C EP+
Sbjct: 397  RSCPRQPSWGVSCPDLRPCAEPH 419



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>O67140:SELA_AQUAE L-seryl-tRNA(Sec) selenium transferase - Aquifex aeolicus|
          Length = 452

 Score = 32.3 bits (72), Expect = 6.7
 Identities = 51/235 (21%), Positives = 96/235 (40%), Gaps = 27/235 (11%)
 Frame = +1

Query: 502  TTPVVNTSAYWFSSSQELIDFKE---GRHASFEY----GRYGNPTTEALEKKMSALEKAE 660
            T  V+NT+      S+++I+F       +++ EY    G+ G+     +EK ++ L  AE
Sbjct: 76   TGVVINTNLGRAPLSKDVINFISEIANGYSNLEYNLEEGKRGSRIAH-IEKYLNELTGAE 134

Query: 661  STVFVASGMYASVAMLSTLVPAGGHIVTTTDLYRKTRIYMETELPKR-GITMTVIRPADM 837
            S+  V +   A   +L+TL      I++  +L      +   ++ K+ G  +  +   + 
Sbjct: 135  SSFVVNNNAGAVFLVLNTLAEGKEVIISRGELVEIGGSFRIPDIMKKSGAILREVGTTNK 194

Query: 838  DALQD--ALDNNNVSLFFTETPTN----PFLRCIDIELVSNMCHNKGALLCIDSTFASPI 999
              + D     N N +L      +N     F+  + +E +  + H  G     D+     I
Sbjct: 195  TKVSDYEGAINQNTALLMKVHKSNFYMEGFVEEVKLEDLVKLGHKYGIPTYYDAGSGLLI 254

Query: 1000 NQK-------------ALTLGADIVVHSATKYIAGHNDVIGGCISGRGELVSKVR 1125
            N K              ++LG D+V  S  K + G      G I G+  L+ K++
Sbjct: 255  NLKEFGISVDEPNFRDCISLGIDLVSGSGDKLLGGPQ---AGIIVGKKNLIEKIK 306



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>Q82WM3:HIS81_NITEU Histidinol-phosphate aminotransferase 1 - Nitrosomonas europaea|
          Length = 359

 Score = 32.0 bits (71), Expect = 8.7
 Identities = 50/243 (20%), Positives = 92/243 (37%), Gaps = 17/243 (6%)
 Frame = +1

Query: 580  ASFEYGRYGNPTTEALEKKMSALEKAESTVFVASGM----------YASVAMLSTLVPAG 729
            A     RY +P   AL++ +S      +T+ V +GM             + ML+   P  
Sbjct: 53   ADTSINRYPDPHAAALKEVLS------TTLSVPAGMEIMLGNGSDEIIQIIMLAAAKPEA 106

Query: 730  GHIVTTTDLYRKTRIYMETELPKRGITMTVIRPADMDALQDALDNNNVSLFFTETPTNPF 909
              +           I     +   GI +      D+D +  A++ +  S+ F   P NP 
Sbjct: 107  KLLTIEPGFAMFKMIATFANMQYIGIPLKPDFSLDIDRMLAAIERHQPSVIFLAYPNNPS 166

Query: 910  LRCIDIELVSNMCHNKGALLCIDSTFASPINQKALTLGAD----IVVHSATKYIAGHNDV 1077
                D   +  +      L+ ID  +     +  +   AD    +V+ + +K   G   +
Sbjct: 167  GNLFDTSALEKIIEISPGLVVIDEAYHPFAGKSFIGRLADYPNLLVMRTLSK--LGLAGL 224

Query: 1078 IGGCISGRGELVS---KVRIYHHVVGGVLNPNASYLILRGMKTLHLRVQCQNNTALRMAQ 1248
              G ++GR E +S   K+R+ ++V   V+    +  I++    L  +      T  R+  
Sbjct: 225  RLGLLAGRPEWLSHLEKLRLPYNV--NVITQLVATKIMQHYDVLQQQADAIRQTRTRLRT 282

Query: 1249 FLE 1257
            FLE
Sbjct: 283  FLE 285


  Database: uniprot_sprot.fasta.out
    Posted date:  Jul 19, 2007  5:58 PM
  Number of letters in database: 100,686,439
  Number of sequences in database:  274,295
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 274295
Number of Hits to DB: 290,981,969
Number of extensions: 6496538
Number of successful extensions: 20115
Number of sequences better than 10.0: 50
Number of HSP's gapped: 19967
Number of HSP's successfully gapped: 51
Length of query: 601
Length of database: 100,686,439
Length adjustment: 119
Effective length of query: 482
Effective length of database: 68,045,334
Effective search space: 32797850988
Effective search space used: 32797850988
Neighboring words threshold: 12
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
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