Clone Information

BLAST Search Result

Clone Name	FLbaf88f11
Clone Library Name	barley_pub

No.	Definition	Score (bits)	E Value
1	P93263:METE_MESCR 5-methyltetrahydropteroyltriglutamate--homocys...	1290	0.0
2	O50008:METE_ARATH 5-methyltetrahydropteroyltriglutamate--homocys...	1288	0.0
3	Q42699:METE_CATRO 5-methyltetrahydropteroyltriglutamate--homocys...	1283	0.0
4	Q42662:METE_SOLSC 5-methyltetrahydropteroyltriglutamate--homocys...	1263	0.0
5	Q6N765:METE_RHOPA 5-methyltetrahydropteroyltriglutamate--homocys...	724	0.0
6	Q9AAW1:METE_CAUCR 5-methyltetrahydropteroyltriglutamate--homocys...	719	0.0
7	Q87BY8:METE_XYLFT 5-methyltetrahydropteroyltriglutamate--homocys...	712	0.0
8	Q8XS05:METE_RALSO 5-methyltetrahydropteroyltriglutamate--homocys...	711	0.0
9	Q9PB72:METE_XYLFA 5-methyltetrahydropteroyltriglutamate--homocys...	707	0.0
10	Q98A73:METE_RHILO 5-methyltetrahydropteroyltriglutamate--homocys...	697	0.0
11	Q9F187:METE_RALEU 5-methyltetrahydropteroyltriglutamate--homocys...	690	0.0
12	Q7NS23:METE_CHRVO 5-methyltetrahydropteroyltriglutamate--homocys...	689	0.0
13	Q9AMV8:METE_BRAJA 5-methyltetrahydropteroyltriglutamate--homocys...	688	0.0
14	Q7W791:METE_BORPA 5-methyltetrahydropteroyltriglutamate--homocys...	684	0.0
15	Q7WKM7:METE_BORBR 5-methyltetrahydropteroyltriglutamate--homocys...	684	0.0
16	Q7VVU3:METE_BORPE 5-methyltetrahydropteroyltriglutamate--homocys...	684	0.0
17	Q93J59:METE_STRCO 5-methyltetrahydropteroyltriglutamate--homocys...	683	0.0
18	Q82UP6:METE_NITEU 5-methyltetrahydropteroyltriglutamate--homocys...	680	0.0
19	P65340:METE_MYCTU 5-methyltetrahydropteroyltriglutamate--homocys...	678	0.0
20	P65341:METE_MYCBO 5-methyltetrahydropteroyltriglutamate--homocys...	678	0.0
21	Q73WJ9:METE_MYCPA 5-methyltetrahydropteroyltriglutamate--homocys...	669	0.0
22	Q82LG4:METE_STRAW 5-methyltetrahydropteroyltriglutamate--homocys...	669	0.0
23	Q9JUT6:METE_NEIMA 5-methyltetrahydropteroyltriglutamate--homocys...	669	0.0
24	P45331:METE_HAEIN 5-methyltetrahydropteroyltriglutamate--homocys...	667	0.0
25	Q9JZQ2:METE_NEIMB 5-methyltetrahydropteroyltriglutamate--homocys...	666	0.0
26	O05564:METE_MYCLE 5-methyltetrahydropteroyltriglutamate--homocys...	661	0.0
27	Q87XJ9:METE_PSESM 5-methyltetrahydropteroyltriglutamate--homocys...	660	0.0
28	Q83A62:METE_COXBU 5-methyltetrahydropteroyltriglutamate--homocys...	659	0.0
29	P57843:METE_PASMU 5-methyltetrahydropteroyltriglutamate--homocys...	657	0.0
30	Q87NA1:METE_VIBPA 5-methyltetrahydropteroyltriglutamate--homocys...	657	0.0
31	Q8FBM1:METE_ECOL6 5-methyltetrahydropteroyltriglutamate--homocys...	648	0.0
32	P57703:METE_PSEAE 5-methyltetrahydropteroyltriglutamate--homocys...	647	0.0
33	Q83IW0:METE_SHIFL 5-methyltetrahydropteroyltriglutamate--homocys...	647	0.0
34	P25665:METE_ECOLI 5-methyltetrahydropteroyltriglutamate--homocys...	646	0.0
35	P57142:METE_BUCAI 5-methyltetrahydropteroyltriglutamate--homocys...	646	0.0
36	Q8ZAL3:METE_YERPE 5-methyltetrahydropteroyltriglutamate--homocys...	645	0.0
37	Q8X8L5:METE_ECO57 5-methyltetrahydropteroyltriglutamate--homocys...	645	0.0
38	Q71YY6:METE_LISMF 5-methyltetrahydropteroyltriglutamate--homocys...	642	0.0
39	Q8G651:METE_BIFLO 5-methyltetrahydropteroyltriglutamate--homocys...	642	0.0
40	Q7MZ74:METE_PHOLL 5-methyltetrahydropteroyltriglutamate--homocys...	641	0.0
41	Q92AX9:METE_LISIN 5-methyltetrahydropteroyltriglutamate--homocys...	641	0.0
42	Q9L6N1:METE_SALTY 5-methyltetrahydropteroyltriglutamate--homocys...	640	0.0
43	Q8CWK1:METE_VIBVU 5-methyltetrahydropteroyltriglutamate--homocys...	639	0.0
44	Q8Z3B6:METE_SALTI 5-methyltetrahydropteroyltriglutamate--homocys...	639	0.0
45	Q7MJM6:METE_VIBVY 5-methyltetrahydropteroyltriglutamate--homocys...	637	0.0
46	Q8Y6K3:METE_LISMO 5-methyltetrahydropteroyltriglutamate--homocys...	634	0.0
47	Q9UT19:METE_SCHPO Probable 5-methyltetrahydropteroyltriglutamate...	633	e-180
48	Q8EIM0:METE_SHEON 5-methyltetrahydropteroyltriglutamate--homocys...	632	e-180
49	Q9KRD8:METE_VIBCH 5-methyltetrahydropteroyltriglutamate--homocys...	630	e-180
50	Q8KA71:METE_BUCAP 5-methyltetrahydropteroyltriglutamate--homocys...	628	e-179
51	Q6LSD6:METE_PHOPR 5-methyltetrahydropteroyltriglutamate--homocys...	626	e-178
52	Q8KRG6:METE_VIBHA 5-methyltetrahydropteroyltriglutamate--homocys...	626	e-178
53	Q9CG55:METE_LACLA 5-methyltetrahydropteroyltriglutamate--homocys...	625	e-178
54	Q97S31:METE_STRPN 5-methyltetrahydropteroyltriglutamate--homocys...	624	e-178
55	Q8FQB2:METE_COREF 5-methyltetrahydropteroyltriglutamate--homocys...	624	e-178
56	Q8DQT2:METE_STRR6 5-methyltetrahydropteroyltriglutamate--homocys...	622	e-177
57	Q7VRI8:METE_BLOFL 5-methyltetrahydropteroyltriglutamate--homocys...	618	e-176
58	Q731W2:METE_BACC1 5-methyltetrahydropteroyltriglutamate--homocys...	617	e-175
59	Q9KFP1:METE_BACHD 5-methyltetrahydropteroyltriglutamate--homocys...	616	e-175
60	P05694:METE_YEAST 5-methyltetrahydropteroyltriglutamate--homocys...	616	e-175
61	Q6KNA9:METE_BACAN 5-methyltetrahydropteroyltriglutamate--homocys...	616	e-175
62	Q725Q3:METE_DESVH 5-methyltetrahydropteroyltriglutamate--homocys...	615	e-175
63	Q89B24:METE_BUCBP 5-methyltetrahydropteroyltriglutamate--homocys...	615	e-175
64	Q819H7:METE_BACCR 5-methyltetrahydropteroyltriglutamate--homocys...	613	e-174
65	Q9PN94:METE_CAMJE 5-methyltetrahydropteroyltriglutamate--homocys...	610	e-173
66	Q88X63:METE_LACPL 5-methyltetrahydropteroyltriglutamate--homocys...	608	e-173
67	Q8CWX6:METE_STRMU 5-methyltetrahydropteroyltriglutamate--homocys...	600	e-170
68	Q8NRB3:METE_CORGL 5-methyltetrahydropteroyltriglutamate--homocys...	600	e-170
69	O67606:METE_AQUAE 5-methyltetrahydropteroyltriglutamate--homocys...	594	e-169
70	P80877:METE_BACSU 5-methyltetrahydropteroyltriglutamate--homocys...	593	e-168
71	P65343:METE_STAAN 5-methyltetrahydropteroyltriglutamate--homocys...	576	e-163
72	P65342:METE_STAAM 5-methyltetrahydropteroyltriglutamate--homocys...	576	e-163
73	Q8NY94:METE_STAAW 5-methyltetrahydropteroyltriglutamate--homocys...	575	e-163
74	Q6GCB6:METE_STAAS 5-methyltetrahydropteroyltriglutamate--homocys...	575	e-163
75	Q6GJW2:METE_STAAR 5-methyltetrahydropteroyltriglutamate--homocys...	575	e-163
76	Q5HIT8:METE_STAAC 5-methyltetrahydropteroyltriglutamate--homocys...	575	e-163
77	P65345:METE_STRA5 5-methyltetrahydropteroyltriglutamate--homocys...	573	e-162
78	P65344:METE_STRA3 5-methyltetrahydropteroyltriglutamate--homocys...	573	e-162
79	Q5HS05:METE_STAEQ 5-methyltetrahydropteroyltriglutamate--homocys...	570	e-162
80	Q8CMP5:METE_STAES 5-methyltetrahydropteroyltriglutamate--homocys...	570	e-161
81	Q8DJY0:METE_SYNEL 5-methyltetrahydropteroyltriglutamate--homocys...	566	e-160
82	Q9X112:METE_THEMA 5-methyltetrahydropteroyltriglutamate--homocys...	555	e-157
83	Q39586:METE_CHLRE 5-methyltetrahydropteroyltriglutamate--homocys...	505	e-142
84	Q4JAI4:METE_SULAC Probable methylcobalamin:homocysteine methyltr...	175	1e-42
85	Q975N4:METE_SULTO Probable methylcobalamin:homocysteine methyltr...	168	1e-40
86	Q980A9:METE_SULSO Probable methylcobalamin:homocysteine methyltr...	161	1e-38
87	Q9YA91:METE_AERPE Probable methylcobalamin:homocysteine methyltr...	157	2e-37
88	Q8TH63:METE_PYRFU Probable methylcobalamin:homocysteine methyltr...	145	9e-34
89	Q5JH51:METE_PYRKO Probable methylcobalamin:homocysteine methyltr...	142	6e-33
90	Q9V085:METE_PYRAB Probable methylcobalamin:homocysteine methyltr...	139	5e-32
91	O58816:METE_PYRHO Probable methylcobalamin:homocysteine methyltr...	137	3e-31
92	P57704:METE_THEAC Probable methylcobalamin:homocysteine methyltr...	100	2e-20
93	Q979L4:METE_THEVO Probable methylcobalamin:homocysteine methyltr...	96	1e-18
94	Q56837:XECA_XANP2 2-hydroxypropyl-CoM lyase - Xanthobacter sp. (...	79	1e-13
95	P55299:METE_METTM Probable methylcobalamin:homocysteine methyltr...	75	1e-12
96	O26869:METE_METTH Probable methylcobalamin:homocysteine methyltr...	73	7e-12
97	Q58868:METE_METJA Probable methylcobalamin:homocysteine methyltr...	72	9e-12
98	Q6XPR3:RPTN_HUMAN Repetin - Homo sapiens (Human)	37	0.56
99	O06458:TRES_THETH Trehalose synthase - Thermus thermophilus	37	0.56
100	P21561:YGY3_HALSQ Hypothetical 50.6 kDa protein in the 5'region ...	35	1.2
101	O13796:YKY1_SCHPO Uncharacterized protein C1142.01 - Schizosacch...	35	1.6
102	Q01613:SHRM1_XENLA Protein Shroom1 - Xenopus laevis (African cla...	35	2.1
103	P53860:PDR16_YEAST Phosphatidylinositol transfer protein PDR16 -...	35	2.1
104	P49244:FABH1_CUPWR 3-oxoacyl-[acyl-carrier-protein] synthase 3 A...	35	2.1
105	P11137:MAP2_HUMAN Microtubule-associated protein 2 - Homo sapien...	34	3.6
106	P21519:MAM_DROME Neurogenic protein mastermind - Drosophila mela...	34	3.6
107	Q7ZAN4:XERD_COREF Tyrosine recombinase xerD - Corynebacterium ef...	33	6.2
108	Q8K1L0:CREB5_MOUSE cAMP response element-binding protein 5 - Mus...	33	8.0
109	Q02930:CREB5_HUMAN cAMP response element-binding protein 5 - Hom...	33	8.0
110	Q4JWT3:PROA_CORJK Gamma-glutamyl phosphate reductase - Corynebac...	33	8.0
111	P49245:FABH2_CUPWR 3-oxoacyl-[acyl-carrier-protein] synthase 3 B...	33	8.0

>P93263:METE_MESCR 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase|
            - Mesembryanthemum crystallinum (Common ice plant)
          Length = 765
 Score = 1290 bits (3339), Expect = 0.0
 Identities = 645/765 (84%), Positives = 685/765 (89%)
 Frame = +1

Query: 73   MASHIVGYPRMGPKRELKFALESFWDGKSSAEDLEKVATDLRASIWKQMAGAGIKYIPSN 252
            MASHIVGYPRMGPKRELKFALESFWDGKS+AEDL+KV+ DLR+SIWKQMA AGIKYIPSN
Sbjct: 1    MASHIVGYPRMGPKRELKFALESFWDGKSTAEDLKKVSADLRSSIWKQMADAGIKYIPSN 60

Query: 253  TFAYYDQVLDTTAMLGAVPDRYSWTGGEINLSTYFSMARGNATVPAMEMTKWFDTNYHFI 432
            TF+YYDQVLDTTAMLGAVP RY WTGGEI    YFSMARGNA+VPAMEMTKWFDTNYHFI
Sbjct: 61   TFSYYDQVLDTTAMLGAVPPRYGWTGGEIEFDVYFSMARGNASVPAMEMTKWFDTNYHFI 120

Query: 433  VPELGPDTKFSYSSHKAINEYKEAKALGVDTVPVLVGPVSYLLLSKAAKGVEKSFXXXXX 612
            VPELGP+  FSY+SHKA+ EYKEAKALGVDTVPVLVGPVSYLLLSK AKGV+KSF     
Sbjct: 121  VPELGPEVNFSYASHKAVLEYKEAKALGVDTVPVLVGPVSYLLLSKQAKGVDKSFDLLSL 180

Query: 613  XXXXXXVYKEVIAELKAAGASWIQFDEPTLVKDPESHQLAAFSAAYTELESTLSGLNVLV 792
                  +YKEV+AELK AGASWIQFDEP LV D ESH+L AFSAAY +LESTLSGLNV+V
Sbjct: 181  LPKILPIYKEVVAELKEAGASWIQFDEPLLVMDLESHKLQAFSAAYADLESTLSGLNVVV 240

Query: 793  ETYFADVPAESYKTLTSLSSVTAYGFDLERGTKTLELVKSGFPAGKYLFAGVVDGRYIWA 972
            ETYFADV AE+YKTL SL  VT YGFDL RGTKTL+LVK+ FP+GKYLFAGVVDGR IWA
Sbjct: 241  ETYFADVTAEAYKTLISLKGVTGYGFDLVRGTKTLDLVKAEFPSGKYLFAGVVDGRNIWA 300

Query: 973  DDLAASLATLQSLEAIVGKDKLVVSTSCSLMHTAVDLVNETKLDDEIKSWLAFAAQKVVE 1152
            +DLAASLATL++LE +VGKDKLVVSTSCS +HTAVDL+NETKLDDEIKSWLAFAAQKV+E
Sbjct: 301  NDLAASLATLEALEGVVGKDKLVVSTSCSFLHTAVDLINETKLDDEIKSWLAFAAQKVLE 360

Query: 1153 VNALAKALAGQKDEXXXXXXXXXXXXXXXXXXVTNEEVQKAATALKGSDHRRATTVSARL 1332
            VNALAKAL+GQKDE                  VTNE VQKAATALKGSDHRRATTVS+RL
Sbjct: 361  VNALAKALSGQKDEAFFSANAAALASRKSSPRVTNEAVQKAATALKGSDHRRATTVSSRL 420

Query: 1333 DAQQKKLNLPVLPTTTIGSFPQTVELRRVRREYKAKKISEEEYTNAIKEEISKVVKIQEE 1512
            DAQQKKLNLP+LPTTTIGSFPQTVELRRVRREYKAKKISEEEY  AIKEEISKVVK+QEE
Sbjct: 421  DAQQKKLNLPILPTTTIGSFPQTVELRRVRREYKAKKISEEEYVKAIKEEISKVVKLQEE 480

Query: 1513 LDIDVLVHGEPERNDMVEYFGEQLSGFTFTANGWVQSYGSRCVKPPIIYGDVSRPNPMTV 1692
            LDIDVLVHGEPERNDMVEYFGEQLSGF F+ANGWVQSYGSRCVKPPIIYGDVSRPNPMTV
Sbjct: 481  LDIDVLVHGEPERNDMVEYFGEQLSGFAFSANGWVQSYGSRCVKPPIIYGDVSRPNPMTV 540

Query: 1693 FWSKMAQSMTARPMKGMLTGPVTILNWSFVRNDQPRFETCYQIALAIKKEVEDLEAGGIQ 1872
            FWS MAQSMTARPMKGMLTGPVTILNWSFVRNDQPR ETCYQIALAIK EVEDLE  GI 
Sbjct: 541  FWSSMAQSMTARPMKGMLTGPVTILNWSFVRNDQPRHETCYQIALAIKNEVEDLEKAGIN 600

Query: 1873 VIQIDEAALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDTTQIHTHMCYSNFNDIIQSI 2052
            VIQIDEAALREGLPLRKSEH FYL WAVHSFRITN GVQDTTQIHTHMCYSNFNDII SI
Sbjct: 601  VIQIDEAALREGLPLRKSEHDFYLKWAVHSFRITNVGVQDTTQIHTHMCYSNFNDIIHSI 660

Query: 2053 INMDADVITIENSRSDEKLLSVFREGVVYGAGIGPGVYDIHSPRIPSKEEIADRVNKMLA 2232
            I+MDADVITIENSRSDEKLLSVFREGV YGAGIGPGVYDIHSPRIP  EE+ADR+ KMLA
Sbjct: 661  IDMDADVITIENSRSDEKLLSVFREGVKYGAGIGPGVYDIHSPRIPPTEELADRIRKMLA 720

Query: 2233 VLDTNILWVNPDCGLKTRKYAEVKPALTNMVEAAKQIRAELAKAQ 2367
            VL++N+LWVNPDCGLKTRKY EV PAL+NMV AAKQ+R ELA A+
Sbjct: 721  VLESNVLWVNPDCGLKTRKYGEVNPALSNMVAAAKQLRQELASAK 765

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>O50008:METE_ARATH 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase|
            - Arabidopsis thaliana (Mouse-ear cress)
          Length = 765

 Score = 1288 bits (3334), Expect = 0.0
 Identities = 644/765 (84%), Positives = 686/765 (89%)
 Frame = +1

Query: 73   MASHIVGYPRMGPKRELKFALESFWDGKSSAEDLEKVATDLRASIWKQMAGAGIKYIPSN 252
            MASHIVGYPRMGPKRELKFALESFWDGKS+AEDL+KV+ DLR+SIWKQM+ AG K+IPSN
Sbjct: 1    MASHIVGYPRMGPKRELKFALESFWDGKSTAEDLQKVSADLRSSIWKQMSAAGTKFIPSN 60

Query: 253  TFAYYDQVLDTTAMLGAVPDRYSWTGGEINLSTYFSMARGNATVPAMEMTKWFDTNYHFI 432
            TFA+YDQVLDTTAMLGAVP RY +TGGEI L  YFSMARGNA+VPAMEMTKWFDTNYH+I
Sbjct: 61   TFAHYDQVLDTTAMLGAVPPRYGYTGGEIGLDVYFSMARGNASVPAMEMTKWFDTNYHYI 120

Query: 433  VPELGPDTKFSYSSHKAINEYKEAKALGVDTVPVLVGPVSYLLLSKAAKGVEKSFXXXXX 612
            VPELGP+  FSY+SHKA+NEYKEAKALGVDTVPVLVGPVSYLLLSKAAKGV+KSF     
Sbjct: 121  VPELGPEVNFSYASHKAVNEYKEAKALGVDTVPVLVGPVSYLLLSKAAKGVDKSFELLSL 180

Query: 613  XXXXXXVYKEVIAELKAAGASWIQFDEPTLVKDPESHQLAAFSAAYTELESTLSGLNVLV 792
                  +YKEVI ELKAAGA+WIQ DEP LV D E  +L AF+ AY ELESTLSGLNVLV
Sbjct: 181  LPKILPIYKEVITELKAAGATWIQLDEPVLVMDLEGQKLQAFTGAYAELESTLSGLNVLV 240

Query: 793  ETYFADVPAESYKTLTSLSSVTAYGFDLERGTKTLELVKSGFPAGKYLFAGVVDGRYIWA 972
            ETYFAD+PAE+YKTLTSL  VTA+GFDL RGTKTL+LVK+GFP GKYLFAGVVDGR IWA
Sbjct: 241  ETYFADIPAEAYKTLTSLKGVTAFGFDLVRGTKTLDLVKAGFPEGKYLFAGVVDGRNIWA 300

Query: 973  DDLAASLATLQSLEAIVGKDKLVVSTSCSLMHTAVDLVNETKLDDEIKSWLAFAAQKVVE 1152
            +D AASL+TLQ+LE IVGKDKLVVSTSCSL+HTAVDL+NETKLDDEIKSWLAFAAQKVVE
Sbjct: 301  NDFAASLSTLQALEGIVGKDKLVVSTSCSLLHTAVDLINETKLDDEIKSWLAFAAQKVVE 360

Query: 1153 VNALAKALAGQKDEXXXXXXXXXXXXXXXXXXVTNEEVQKAATALKGSDHRRATTVSARL 1332
            VNALAKALAGQKDE                  VTNE VQKAA ALKGSDHRRAT VSARL
Sbjct: 361  VNALAKALAGQKDEALFSANAAALASRRSSPRVTNEGVQKAAAALKGSDHRRATNVSARL 420

Query: 1333 DAQQKKLNLPVLPTTTIGSFPQTVELRRVRREYKAKKISEEEYTNAIKEEISKVVKIQEE 1512
            DAQQKKLNLP+LPTTTIGSFPQTVELRRVRREYKAKK+SEE+Y  AIKEEI KVV +QEE
Sbjct: 421  DAQQKKLNLPILPTTTIGSFPQTVELRRVRREYKAKKVSEEDYVKAIKEEIKKVVDLQEE 480

Query: 1513 LDIDVLVHGEPERNDMVEYFGEQLSGFTFTANGWVQSYGSRCVKPPIIYGDVSRPNPMTV 1692
            LDIDVLVHGEPERNDMVEYFGEQLSGF FTANGWVQSYGSRCVKPP+IYGDVSRP  MTV
Sbjct: 481  LDIDVLVHGEPERNDMVEYFGEQLSGFAFTANGWVQSYGSRCVKPPVIYGDVSRPKAMTV 540

Query: 1693 FWSKMAQSMTARPMKGMLTGPVTILNWSFVRNDQPRFETCYQIALAIKKEVEDLEAGGIQ 1872
            FWS MAQSMT+RPMKGMLTGPVTILNWSFVRNDQPR ETCYQIALAIK EVEDLE GGI 
Sbjct: 541  FWSAMAQSMTSRPMKGMLTGPVTILNWSFVRNDQPRHETCYQIALAIKDEVEDLEKGGIG 600

Query: 1873 VIQIDEAALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDTTQIHTHMCYSNFNDIIQSI 2052
            VIQIDEAALREGLPLRKSEHAFYLDWAVHSFRITNCGVQD+TQIHTHMCYS+FNDII SI
Sbjct: 601  VIQIDEAALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDSTQIHTHMCYSHFNDIIHSI 660

Query: 2053 INMDADVITIENSRSDEKLLSVFREGVVYGAGIGPGVYDIHSPRIPSKEEIADRVNKMLA 2232
            I+MDADVITIENSRSDEKLLSVFREGV YGAGIGPGVYDIHSPRIPS EEIADRVNKMLA
Sbjct: 661  IDMDADVITIENSRSDEKLLSVFREGVKYGAGIGPGVYDIHSPRIPSSEEIADRVNKMLA 720

Query: 2233 VLDTNILWVNPDCGLKTRKYAEVKPALTNMVEAAKQIRAELAKAQ 2367
            VL+ NILWVNPDCGLKTRKY EVKPAL NMV+AAK IR++LA A+
Sbjct: 721  VLEQNILWVNPDCGLKTRKYTEVKPALKNMVDAAKLIRSQLASAK 765

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>Q42699:METE_CATRO 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase|
            - Catharanthus roseus (Rosy periwinkle) (Madagascar
            periwinkle)
          Length = 765

 Score = 1283 bits (3320), Expect = 0.0
 Identities = 643/765 (84%), Positives = 684/765 (89%)
 Frame = +1

Query: 73   MASHIVGYPRMGPKRELKFALESFWDGKSSAEDLEKVATDLRASIWKQMAGAGIKYIPSN 252
            MASHIVGYPRMGPKRELKFALESFWD KSSAEDL+KVA DLR+SIWKQMA AGIKYIPSN
Sbjct: 1    MASHIVGYPRMGPKRELKFALESFWDKKSSAEDLQKVAADLRSSIWKQMADAGIKYIPSN 60

Query: 253  TFAYYDQVLDTTAMLGAVPDRYSWTGGEINLSTYFSMARGNATVPAMEMTKWFDTNYHFI 432
            TF+YYDQVLDT  MLGAVP RY++ GGEI   TYFSMARGNA+VPAMEMTKWFDTNYH+I
Sbjct: 61   TFSYYDQVLDTATMLGAVPPRYNFAGGEIGFDTYFSMARGNASVPAMEMTKWFDTNYHYI 120

Query: 433  VPELGPDTKFSYSSHKAINEYKEAKALGVDTVPVLVGPVSYLLLSKAAKGVEKSFXXXXX 612
            VPELGP+  FSY+SHKA+NEYKEAK LGVDTVPVLVGPV++LLLSK AKGVEK+F     
Sbjct: 121  VPELGPEVNFSYASHKAVNEYKEAKELGVDTVPVLVGPVTFLLLSKPAKGVEKTFPLLSL 180

Query: 613  XXXXXXVYKEVIAELKAAGASWIQFDEPTLVKDPESHQLAAFSAAYTELESTLSGLNVLV 792
                  VYKEVI ELKAAGASWIQFDEPTLV D ESHQL AF+ AY+ELESTLSGLNV+V
Sbjct: 181  LDKILPVYKEVIGELKAAGASWIQFDEPTLVLDLESHQLEAFTKAYSELESTLSGLNVIV 240

Query: 793  ETYFADVPAESYKTLTSLSSVTAYGFDLERGTKTLELVKSGFPAGKYLFAGVVDGRYIWA 972
            ETYFAD+PAE+YK LT+L  VT +GFDL RG KTL+L+K GFP+GKYLFAGVVDGR IWA
Sbjct: 241  ETYFADIPAETYKILTALKGVTGFGFDLVRGAKTLDLIKGGFPSGKYLFAGVVDGRNIWA 300

Query: 973  DDLAASLATLQSLEAIVGKDKLVVSTSCSLMHTAVDLVNETKLDDEIKSWLAFAAQKVVE 1152
            +DLAASL+TLQSLE IVGKDKLVVSTSCSL+HTAVDLVNE KLD EIKSWLAFAAQKVVE
Sbjct: 301  NDLAASLSTLQSLEGIVGKDKLVVSTSCSLLHTAVDLVNEPKLDKEIKSWLAFAAQKVVE 360

Query: 1153 VNALAKALAGQKDEXXXXXXXXXXXXXXXXXXVTNEEVQKAATALKGSDHRRATTVSARL 1332
            VNALAKALAG+KDE                  VTN+ VQKAA AL+GSDHRRATTVSARL
Sbjct: 361  VNALAKALAGEKDEAFFSENAAAQASRKSSPRVTNQAVQKAAAALRGSDHRRATTVSARL 420

Query: 1333 DAQQKKLNLPVLPTTTIGSFPQTVELRRVRREYKAKKISEEEYTNAIKEEISKVVKIQEE 1512
            DAQQKKLNLPVLPTTTIGSFPQT+ELRRVRREYKAKKISE++Y  AIKEEISKVVK+QEE
Sbjct: 421  DAQQKKLNLPVLPTTTIGSFPQTLELRRVRREYKAKKISEDDYVKAIKEEISKVVKLQEE 480

Query: 1513 LDIDVLVHGEPERNDMVEYFGEQLSGFTFTANGWVQSYGSRCVKPPIIYGDVSRPNPMTV 1692
            LDIDVLVHGEPERNDMVEYFGEQLSGF FTANGWVQSYGSRCVKPPIIYGDVSRPNPMTV
Sbjct: 481  LDIDVLVHGEPERNDMVEYFGEQLSGFAFTANGWVQSYGSRCVKPPIIYGDVSRPNPMTV 540

Query: 1693 FWSKMAQSMTARPMKGMLTGPVTILNWSFVRNDQPRFETCYQIALAIKKEVEDLEAGGIQ 1872
            FWS+ AQSMT RPMKGMLTGPVTILNWSFVRNDQPRFETCYQIALAIK EVEDLE  GI 
Sbjct: 541  FWSQTAQSMTKRPMKGMLTGPVTILNWSFVRNDQPRFETCYQIALAIKDEVEDLEKAGIN 600

Query: 1873 VIQIDEAALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDTTQIHTHMCYSNFNDIIQSI 2052
            VIQIDEAALREGLPLRK+EHAFYLDWAVHSFRITN  +QDTTQIHTHMCYSNFNDII SI
Sbjct: 601  VIQIDEAALREGLPLRKAEHAFYLDWAVHSFRITNLPLQDTTQIHTHMCYSNFNDIIHSI 660

Query: 2053 INMDADVITIENSRSDEKLLSVFREGVVYGAGIGPGVYDIHSPRIPSKEEIADRVNKMLA 2232
            I+MDADV+TIENSRS EKLLSVFREGV YGAGIGPGVYDIHSPRIPS EEIADR+NKMLA
Sbjct: 661  IDMDADVMTIENSRSSEKLLSVFREGVKYGAGIGPGVYDIHSPRIPSTEEIADRINKMLA 720

Query: 2233 VLDTNILWVNPDCGLKTRKYAEVKPALTNMVEAAKQIRAELAKAQ 2367
            VLDTNILWVNPDCGLKTRKYAEVKPAL NMV AAK IR +LA A+
Sbjct: 721  VLDTNILWVNPDCGLKTRKYAEVKPALENMVSAAKLIRTQLASAK 765

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>Q42662:METE_SOLSC 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase|
            - Solenostemon scutellarioides (Coleus) (Coleus blumei)
          Length = 764

 Score = 1263 bits (3267), Expect = 0.0
 Identities = 635/765 (83%), Positives = 675/765 (88%)
 Frame = +1

Query: 73   MASHIVGYPRMGPKRELKFALESFWDGKSSAEDLEKVATDLRASIWKQMAGAGIKYIPSN 252
            MASHIVGYPRMGPKRELKFALESFWDGKSSAEDLEK    L   + KQM+ AGIKYIPSN
Sbjct: 1    MASHIVGYPRMGPKRELKFALESFWDGKSSAEDLEKCQLILGIHL-KQMSDAGIKYIPSN 59

Query: 253  TFAYYDQVLDTTAMLGAVPDRYSWTGGEINLSTYFSMARGNATVPAMEMTKWFDTNYHFI 432
            TF+YYDQVLDTTAMLGAVP RY+WTGGEI  STYFSMARGNA+VPAMEMTKWFDTNYHFI
Sbjct: 60   TFSYYDQVLDTTAMLGAVPPRYNWTGGEIGFSTYFSMARGNASVPAMEMTKWFDTNYHFI 119

Query: 433  VPELGPDTKFSYSSHKAINEYKEAKALGVDTVPVLVGPVSYLLLSKAAKGVEKSFXXXXX 612
            VPELGPD KFSY+SHKA+NEYKEAKALGVDTVPVLVGPVSYL+LSK AKGVEK+F     
Sbjct: 120  VPELGPDVKFSYASHKAVNEYKEAKALGVDTVPVLVGPVSYLILSKPAKGVEKTFPLLSL 179

Query: 613  XXXXXXVYKEVIAELKAAGASWIQFDEPTLVKDPESHQLAAFSAAYTELESTLSGLNVLV 792
                  +YKEVIAELKAAGASWIQFDEPTLV D ESHQL AF+ AY ELES+LSGL+ L+
Sbjct: 180  LDKILPIYKEVIAELKAAGASWIQFDEPTLVLDLESHQLDAFTKAYAELESSLSGLSTLI 239

Query: 793  ETYFADVPAESYKTLTSLSSVTAYGFDLERGTKTLELVKSGFPAGKYLFAGVVDGRYIWA 972
            ETYFADVPA +YKTLTSLS ++ +GFDL RG +T+EL+K GFP+GKYLFAGVVDGR IWA
Sbjct: 240  ETYFADVPAPAYKTLTSLSGISGFGFDLVRGAQTIELIKGGFPSGKYLFAGVVDGRNIWA 299

Query: 973  DDLAASLATLQSLEAIVGKDKLVVSTSCSLMHTAVDLVNETKLDDEIKSWLAFAAQKVVE 1152
            +DLA+S+ TLQ+LE IVGKDKLVVSTS SL+HTAVDLVNE KLD EIKSWLAFAAQK+VE
Sbjct: 300  NDLASSITTLQALEGIVGKDKLVVSTSSSLLHTAVDLVNEPKLDQEIKSWLAFAAQKIVE 359

Query: 1153 VNALAKALAGQKDEXXXXXXXXXXXXXXXXXXVTNEEVQKAATALKGSDHRRATTVSARL 1332
            VNALAKAL G KDE                  V NE VQKAA AL+GS+HRR T VSARL
Sbjct: 360  VNALAKALTGHKDEAFFSPNAAAQASRKSSPRVNNEAVQKAAAALRGSEHRRVTNVSARL 419

Query: 1333 DAQQKKLNLPVLPTTTIGSFPQTVELRRVRREYKAKKISEEEYTNAIKEEISKVVKIQEE 1512
            DAQQKKLNLP+LPTTTIGSFPQTVELRRVRRE+K  +ISEEEY  AIKEEI+KVVK+QEE
Sbjct: 420  DAQQKKLNLPILPTTTIGSFPQTVELRRVRREFKPTRISEEEYVKAIKEEINKVVKLQEE 479

Query: 1513 LDIDVLVHGEPERNDMVEYFGEQLSGFTFTANGWVQSYGSRCVKPPIIYGDVSRPNPMTV 1692
            LDIDVLVHGEPERNDMVEYFGEQLSGF FTANGWVQSYGSRCVKPPIIYGDVSRP PMTV
Sbjct: 480  LDIDVLVHGEPERNDMVEYFGEQLSGFAFTANGWVQSYGSRCVKPPIIYGDVSRPKPMTV 539

Query: 1693 FWSKMAQSMTARPMKGMLTGPVTILNWSFVRNDQPRFETCYQIALAIKKEVEDLEAGGIQ 1872
            FWS  AQSMT RPMKGMLTGPVTILNWSFVRNDQPRFETCYQIALAIK EVEDLE  GI 
Sbjct: 540  FWSTAAQSMTQRPMKGMLTGPVTILNWSFVRNDQPRFETCYQIALAIKDEVEDLEKAGIT 599

Query: 1873 VIQIDEAALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDTTQIHTHMCYSNFNDIIQSI 2052
            VIQIDEAALREGLPLRKSEHAFYLDWAVHSFRITN GVQDTTQIHTHMCYSNFNDII SI
Sbjct: 600  VIQIDEAALREGLPLRKSEHAFYLDWAVHSFRITNVGVQDTTQIHTHMCYSNFNDIIHSI 659

Query: 2053 INMDADVITIENSRSDEKLLSVFREGVVYGAGIGPGVYDIHSPRIPSKEEIADRVNKMLA 2232
            INMDADVITIENSRSDEKLLSVFREGV YGAGIGPGVYDIHSPRIPS EEIADR+NKMLA
Sbjct: 660  INMDADVITIENSRSDEKLLSVFREGVKYGAGIGPGVYDIHSPRIPSTEEIADRINKMLA 719

Query: 2233 VLDTNILWVNPDCGLKTRKYAEVKPALTNMVEAAKQIRAELAKAQ 2367
            VL+TNILWVNPDCGLKTRKYAEVKPAL NMV AAK +R +LA A+
Sbjct: 720  VLETNILWVNPDCGLKTRKYAEVKPALENMVAAAKLLRTQLASAK 764

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>Q6N765:METE_RHOPA 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase|
            - Rhodopseudomonas palustris
          Length = 788

 Score =  724 bits (1870), Expect = 0.0
 Identities = 389/780 (49%), Positives = 500/780 (64%), Gaps = 22/780 (2%)
 Frame = +1

Query: 73   MASHIVGYPRMGPKRELKFALESFWDGKSSAEDLEKVATDLRASIWKQMAGAGIKYIPSN 252
            +A   +G PR+GP+RELK ALESFW GKS+  DL KVA  LRA+ W + +  G+  IPSN
Sbjct: 10   LAVATLGTPRIGPRRELKSALESFWAGKSTEADLLKVAAALRAANWARQSARGVSVIPSN 69

Query: 253  TFAYYDQVLDTTAMLGAVPDRYSWTGGEINLSTYFSMARGNAT----------------- 381
             F+ YDQVLDT+ M+GA+P+ Y W GG ++L+TYF+MARG                    
Sbjct: 70   DFSLYDQVLDTSVMVGAIPEIYGWRGGPVSLATYFAMARGTQAEIAGHGCANGHHHGDST 129

Query: 382  ---VPAMEMTKWFDTNYHFIVPELGPDTKFSYSSHKAINEYKEAKALGVDTVPVLVGPVS 552
               VPA EMTKWFDTNYH++VPE      F  +S K + EY+EAKALG DT PVL+GPV+
Sbjct: 130  PQGVPAQEMTKWFDTNYHYMVPEFSAGQSFQLASVKPLEEYREAKALGYDTRPVLLGPVT 189

Query: 553  YLLLSKAAKGVEKSFXXXXXXXXXXXVYKEVIAELKAAGASWIQFDEPTLVKDPESHQLA 732
            YL L K+A   +              VY E++  L AAGA W+Q DEP LV D +  +  
Sbjct: 190  YLKLGKSA---DAGLDVLSLLPKLVPVYIEILGRLAAAGAKWVQLDEPALVLDLDDRERL 246

Query: 733  AFSAAYTELESTLSGLNVLVETYFADVPAESYKTLTSLSSVTAYGFDLERGTKTLELVKS 912
            AF  AY ++   L  L++++ TYF  +  ++  T  +L  +     DL R  K +  V +
Sbjct: 247  AFRDAYGQIARELPHLDIMLTTYFGGL-GDNLDTALALP-IAGLHLDLVRAPKQINAVIA 304

Query: 913  GFPAGKYLFAGVVDGRYIWADDLAASLATLQSLEAIVGKDKLVVSTSCSLMHTAVDLVNE 1092
              P    L  GVVDGR IW  DL   L  ++ +    G +++ ++ SCSL+H  VDL  E
Sbjct: 305  KGPKDLVLSLGVVDGRNIWRADLPDLLDRVEPIVQQRGAERVQLAPSCSLLHVPVDLELE 364

Query: 1093 TKLDDEIKSWLAFAAQKVVEVNALAKALAGQKD--EXXXXXXXXXXXXXXXXXXVTNEEV 1266
            T LD ++KSWL+F+ QK+ E++ L++AL+G +   +                  V +  V
Sbjct: 365  TGLDPDLKSWLSFSLQKMGELSTLSRALSGDRAAVQDQLSASAKAAATRRKSPKVHDMAV 424

Query: 1267 QKAATALKGSDHRRATTVSARLDAQQKKLNLPVLPTTTIGSFPQTVELRRVRREYKAKKI 1446
               A A+  +  +R +  +AR   Q ++L LP  PTTTIGSFPQT ++R+ R  +    I
Sbjct: 425  SSRAAAVTPAMTQRNSGFAARATLQHQRLQLPAFPTTTIGSFPQTAQIRQARAAHAKGAI 484

Query: 1447 SEEEYTNAIKEEISKVVKIQEELDIDVLVHGEPERNDMVEYFGEQLSGFTFTANGWVQSY 1626
            S+ +Y   ++ E ++ ++ QE++ +DVLVHGE ERNDMV+YFGEQLSGF FT  GWVQSY
Sbjct: 485  SDADYNTFLRGETARAIQWQEKVGLDVLVHGEFERNDMVQYFGEQLSGFAFTKEGWVQSY 544

Query: 1627 GSRCVKPPIIYGDVSRPNPMTVFWSKMAQSMTARPMKGMLTGPVTILNWSFVRNDQPRFE 1806
            GSRCV+PPI++GDVSRP PMTV W K AQS+T RPMKGMLTGPVTILNWSFVR+D PR  
Sbjct: 545  GSRCVRPPILFGDVSRPKPMTVGWWKYAQSLTGRPMKGMLTGPVTILNWSFVRDDVPRST 604

Query: 1807 TCYQIALAIKKEVEDLEAGGIQVIQIDEAALREGLPLRKSEHAFYLDWAVHSFRITNCGV 1986
             C QIALAI+ EV DLE  G  +IQIDEAALREGLPLR+SE   YLDWAV  FR+ + GV
Sbjct: 605  ACLQIALAIRDEVGDLEQAGATMIQIDEAALREGLPLRRSEWKGYLDWAVECFRLCSSGV 664

Query: 1987 QDTTQIHTHMCYSNFNDIIQSIINMDADVITIENSRSDEKLLSVFREGVVYGAGIGPGVY 2166
            +D TQIHTHMCYS FNDII +I  MDADVI+IE SRS  +LL  F+    Y   IGPGVY
Sbjct: 665  KDETQIHTHMCYSEFNDIIDAIAAMDADVISIETSRSKMELLDAFKT-YKYPNEIGPGVY 723

Query: 2167 DIHSPRIPSKEEIADRVNKMLAVLDTNILWVNPDCGLKTRKYAEVKPALTNMVEAAKQIR 2346
            DIHSPR+PS EE+   +      L    LWVNPDCGLKTR + EV+ AL NMVEAA+QIR
Sbjct: 724  DIHSPRVPSVEEMTTLLQLARQRLSDGQLWVNPDCGLKTRGWDEVQGALVNMVEAARQIR 783

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>Q9AAW1:METE_CAUCR 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase|
            - Caulobacter crescentus (Caulobacter vibrioides)
          Length = 777

 Score =  719 bits (1856), Expect = 0.0
 Identities = 387/775 (49%), Positives = 493/775 (63%), Gaps = 21/775 (2%)
 Frame = +1

Query: 88   VGYPRMGPKRELKFALESFWDGKSSAEDLEKVATDLRASIWKQMAGAGIKYIPSNTFAYY 267
            +G+PR+GPKRELKFALE++W GK+ A+ L   A DLRA  W + A  G+ ++PSN F+ Y
Sbjct: 8    LGFPRIGPKRELKFALEAYWAGKTDADALLDTARDLRAKTWTRQAALGVAHVPSNDFSLY 67

Query: 268  DQVLDTTAMLGAVPDRYSWTGGEINLSTYFSMARGNAT-------------------VPA 390
            D VLDT  M+GA+P  Y W+GG ++L+TYF+MARG+                     VPA
Sbjct: 68   DHVLDTAVMVGAIPAAYGWSGGTVDLATYFAMARGDQGRPAAEACGPGCGHAPGADGVPA 127

Query: 391  MEMTKWFDTNYHFIVPELGPDTKFSYSSHKAINEYKEAKALGVDTVPVLVGPVSYLLLSK 570
            +EMTKWFDTNYH++ PEL P   F+ +S K ++E+ EAKALGV T PVL+GPV++L   K
Sbjct: 128  LEMTKWFDTNYHYLAPELSPGQAFALTSSKPVDEFLEAKALGVHTRPVLLGPVTFL---K 184

Query: 571  AAKGVEKSFXXXXXXXXXXXVYKEVIAELKAAGASWIQFDEPTLVKDPESHQLAAFSAAY 750
             AK   + F           VY +V+  L AAGA W+Q DEP L  D    + A    AY
Sbjct: 185  LAKTKAEGFSPLSLLSALLPVYGQVLRGLAAAGADWVQIDEPCLALDLTDFERAELRRAY 244

Query: 751  TELESTLSGLNVLVETYFADVPAESYKTLTSLSSVTAYGFDLERGTKTLELVKSGFPAGK 930
              L     G+ +++ +YF     E+  T  +L  V     DL R    LE   +      
Sbjct: 245  GALTHAAPGVRLMLTSYFGGY-GENLATAVNLP-VEGLHLDLVRAPDELEAALAASRESL 302

Query: 931  YLFAGVVDGRYIWADDLAASLATLQSLEAIVGKDKLVVSTSCSLMHTAVDLVNETKLDDE 1110
             L  GV+DGR +W  DL A L  L+ + A  G D++V++ SCSL+HT +DL  ET LD E
Sbjct: 303  VLSLGVIDGRNVWRADLPALLDRLEPVVARRGSDRVVLAPSCSLLHTPIDLDLETALDPE 362

Query: 1111 IKSWLAFAAQKVVEVNALAKALAGQKDEXXXXXXXXXXXXXXXXXX--VTNEEVQKAATA 1284
            I+ WLAFA QKV  +  LA+AL G +                      + + +V +   A
Sbjct: 363  IRQWLAFAVQKVEALAVLAQALNGGRASVAAALEASAQAARARATSPRIHDPKVAERLAA 422

Query: 1285 LKGSDHRRATTVSARLDAQQKKLNLPVLPTTTIGSFPQTVELRRVRREYKAKKISEEEYT 1464
            +     RR +    R +AQ+ +LNLP LPTTTIGSFPQT E+R+ R  +   +IS+  Y 
Sbjct: 423  VTPDMTRRRSPYDQRREAQRARLNLPPLPTTTIGSFPQTTEVRQARAAFAKGQISDATYE 482

Query: 1465 NAIKEEISKVVKIQEELDIDVLVHGEPERNDMVEYFGEQLSGFTFTANGWVQSYGSRCVK 1644
              +++E ++ V  QE + +DVLVHGE ERNDMV+YFGEQL+GF FT +GWVQSYGSRCV+
Sbjct: 483  AFLRQETARAVAWQETVGLDVLVHGEFERNDMVQYFGEQLAGFAFTQSGWVQSYGSRCVR 542

Query: 1645 PPIIYGDVSRPNPMTVFWSKMAQSMTARPMKGMLTGPVTILNWSFVRNDQPRFETCYQIA 1824
            PPI++GDVSRP PMTV W + AQ +T RPMKGMLTGPVTILNWSFVR+D PR   C QIA
Sbjct: 543  PPILFGDVSRPAPMTVDWWRYAQGLTRRPMKGMLTGPVTILNWSFVRDDLPRETACRQIA 602

Query: 1825 LAIKKEVEDLEAGGIQVIQIDEAALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDTTQI 2004
            LAI+ EV DLEA G  +IQIDEAALREGLPLR+ +   YLDWAV SFR+   GV D TQI
Sbjct: 603  LAIRDEVVDLEATGAAIIQIDEAALREGLPLRRGDWDAYLDWAVESFRLAASGVADATQI 662

Query: 2005 HTHMCYSNFNDIIQSIINMDADVITIENSRSDEKLLSVFREGVVYGAGIGPGVYDIHSPR 2184
            HTHMCYS FNDII +I  MDADVI+IE +RS  +LL  F  G  Y A IGPGVYDIHSPR
Sbjct: 663  HTHMCYSEFNDIIAAIGAMDADVISIETARSKMELLDAF-VGYAYPAQIGPGVYDIHSPR 721

Query: 2185 IPSKEEIADRVNKMLAVLDTNILWVNPDCGLKTRKYAEVKPALTNMVEAAKQIRA 2349
            +P+ EE+   +      L    LWVNPDCGLKTRK+ E + A+ NMVEAA++ RA
Sbjct: 722  VPAVEEMTTLLAAARQRLAGEQLWVNPDCGLKTRKWPETQAAIVNMVEAARRARA 776

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>Q87BY8:METE_XYLFT 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase|
            - Xylella fastidiosa (strain Temecula1 / ATCC 700964)
          Length = 758

 Score =  712 bits (1837), Expect = 0.0
 Identities = 386/760 (50%), Positives = 489/760 (64%), Gaps = 5/760 (0%)
 Frame = +1

Query: 88   VGYPRMGPKRELKFALESFWDGKSSAEDLEKVATDLRASIWKQMAGAGIKYIPSNTFAYY 267
            +G+PR+G +RELK ALES W G++ A  L+  A +LRA  W+    AG+   PSN F+ Y
Sbjct: 7    LGFPRIGARRELKRALESHWRGETDATQLQHTARELRARHWRLQRDAGVDLPPSNDFSLY 66

Query: 268  DQVLDTTAMLGAVPDRYSWTGGEINLSTYFSMARG----NATVPAMEMTKWFDTNYHFIV 435
            D VLDT  +  A+P RY        L+ YF+MARG    N  + A+EMTKWFDTNYH++V
Sbjct: 67   DHVLDTAFLFDAIPQRYRGLVDADPLAGYFAMARGRQADNIDLHALEMTKWFDTNYHYLV 126

Query: 436  PELGPDTKFSYSSHKAINEYKEAKALGVDTVPVLVGPVSYLLLSKAAKGVEKSFXXXXXX 615
            PEL  D  F+   +K I E++EA ALG+ T PVL+GPVS+LLLSK   G  +        
Sbjct: 127  PELHRDQHFALRGNKPIAEFEEALALGITTRPVLLGPVSFLLLSKTVDGSNR----LDLL 182

Query: 616  XXXXXVYKEVIAELKAAGASWIQFDEPTLVKDPESHQLAAFSAAYTELESTLSGLNVLVE 795
                 VY +++ +L+ +GA W+Q DEPTLV D ++    AF  AY  L        +L+ 
Sbjct: 183  ERLLPVYTQLLRQLQESGAEWVQIDEPTLVLDLDAQTQQAFRKAYAILNQGPRP-KLLLT 241

Query: 796  TYFADVPAESYKTLTSLSSVTAYGFDLERGTKTLELVKSGFPAGKYLFAGVVDGRYIWAD 975
            +YF   P      L           DL RGT+ L+ V +  PAG+ L AG+V+GR IW  
Sbjct: 242  SYFG--PLGDNLELALQLPADGLHIDLVRGTEQLDAVLNTLPAGRVLSAGLVNGRNIWRT 299

Query: 976  DLAASLATLQSLEAIVGKDKLVVSTSCSLMHTAVDLVNETKLDDEIKSWLAFAAQKVVEV 1155
            DL  +L   +  +  VG D+L ++ SCSL+H  VDL  E  LD ++++WLAFA QK+ E+
Sbjct: 300  DLDNALTMARYAQGHVGADRLWLAPSCSLLHVPVDLEQEKNLDADVRNWLAFAKQKLSEL 359

Query: 1156 NALAKALAGQKD-EXXXXXXXXXXXXXXXXXXVTNEEVQKAATALKGSDHRRATTVSARL 1332
              LA AL  + + E                  V   +V +   AL     RR T    R 
Sbjct: 360  RVLADALDNKPEAETALTQTRQALEARRQSPKVHRPDVAQRLAALTPDTTRRNTAYPQRS 419

Query: 1333 DAQQKKLNLPVLPTTTIGSFPQTVELRRVRREYKAKKISEEEYTNAIKEEISKVVKIQEE 1512
             AQQ  LNLP  PTTTIGSFPQT+E+R  R ++K+ K+SE +Y   +K E  + V+ QEE
Sbjct: 420  QAQQHTLNLPAYPTTTIGSFPQTLEVREARAQFKSGKLSESDYEAFLKAETERCVRTQEE 479

Query: 1513 LDIDVLVHGEPERNDMVEYFGEQLSGFTFTANGWVQSYGSRCVKPPIIYGDVSRPNPMTV 1692
            + +DVLVHGE ERNDMVEYFGEQL GF FT  GWVQSYGSRCVKPPIIYGDV RP PMTV
Sbjct: 480  IGLDVLVHGEFERNDMVEYFGEQLDGFIFTKLGWVQSYGSRCVKPPIIYGDVVRPAPMTV 539

Query: 1693 FWSKMAQSMTARPMKGMLTGPVTILNWSFVRNDQPRFETCYQIALAIKKEVEDLEAGGIQ 1872
             WS  AQS+T +PMKGMLTGPVT+L WSFVR+DQ R +TC QIALA++ EV+DLE  GI+
Sbjct: 540  TWSAYAQSLTDKPMKGMLTGPVTMLQWSFVRDDQERAQTCRQIALALRDEVQDLEKAGIK 599

Query: 1873 VIQIDEAALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDTTQIHTHMCYSNFNDIIQSI 2052
            VIQIDE A+REGLPLR+ E A YL+WAV SFRI +  V DTTQIHTHMCYS FNDII+++
Sbjct: 600  VIQIDEPAIREGLPLRRGEWADYLNWAVESFRIASSNVHDTTQIHTHMCYSEFNDIIEAV 659

Query: 2053 INMDADVITIENSRSDEKLLSVFREGVVYGAGIGPGVYDIHSPRIPSKEEIADRVNKMLA 2232
              +DADVI+IE SRS  +LL  F +   Y   IGPGVYDIHSPR+P +EE+   + K  A
Sbjct: 660  AALDADVISIETSRSRMELLDAFVK-FRYPNAIGPGVYDIHSPRVPQEEEMVLLLKKARA 718

Query: 2233 VLDTNILWVNPDCGLKTRKYAEVKPALTNMVEAAKQIRAE 2352
            VL    LWVNPDCGLKTR + E + AL  MV AA+++RAE
Sbjct: 719  VLPPEQLWVNPDCGLKTRGWKETRAALQTMVHAAQRLRAE 758

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>Q8XS05:METE_RALSO 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase|
            - Ralstonia solanacearum (Pseudomonas solanacearum)
          Length = 776

 Score =  711 bits (1834), Expect = 0.0
 Identities = 385/763 (50%), Positives = 485/763 (63%), Gaps = 2/763 (0%)
 Frame = +1

Query: 82   HIVGYPRMGPKRELKFALESFWDGKSSAEDLEKVATDLRASIWKQMAGAGIKYIPSNTFA 261
            H +GYPR+G +RELKFALESFW G S+  DL      LR   W     AG+ ++    FA
Sbjct: 5    HTLGYPRIGAQRELKFALESFWKGASTEADLRDTGRALRERHWNAQRDAGLDFVTVGDFA 64

Query: 262  YYDQVLDTTAMLGAVPDRYSWTGGEINLSTYFSMARGNATVPAMEMTKWFDTNYHFIVPE 441
            +YDQVL T A+LGA+P RY +   ++ L+  F +ARGNA   AMEMTKWFDTNYH++VPE
Sbjct: 65   WYDQVLQTAALLGALPTRYGFDPAQLTLAQSFVLARGNADHAAMEMTKWFDTNYHYLVPE 124

Query: 442  LGPDTKFSYSSHKAINEYKEAKALGVDTVPVLVGPVSYLLLSKAAKGVEKSFXXXXXXXX 621
            L PD +F   +    +E +EA+A G      L+GPV++L L+KA  G+            
Sbjct: 125  LTPDLRFGPGTGWLFDEVREAQAAGHRVKVALLGPVTFLHLAKARGGLADKLSLLPQLLP 184

Query: 622  XXXVYKEVIAELKAAGASWIQFDEPTLVKDPESHQLAAFSAAYTELESTLSGLNVLVETY 801
                Y  V+  L A G  W+Q DEP LV D       A+  AY  L +   G  +L+ TY
Sbjct: 185  ---AYAAVLKRLAAEGVEWVQIDEPALVLDLPQAWSDAYGPAYATLAAA-GGPRLLLATY 240

Query: 802  FADVPAESYKTLTSLSSVTAYGFDLERGTKTLELVKSGFPAGKYLFAGVVDGRYIWADDL 981
            F    A  +  L     V     DL R  + LE   + +PA K L AGVVDGR IW  DL
Sbjct: 241  FE--AASHHAALIRSLPVAGVHLDLVRAPQQLEAF-APWPADKVLSAGVVDGRNIWRTDL 297

Query: 982  AASLATLQSLEAIVGKDKLVVSTSCSLMHTAVDLVNETKLDDEIKSWLAFAAQKVVEVNA 1161
              +LA +  L   +G ++L ++ SCSL+H  VDL  ET+LDDE+K WLAFA QK+ E+  
Sbjct: 298  EQALARVAPLAQTLG-ERLWLAPSCSLLHVPVDLAAETRLDDELKGWLAFARQKLDELAV 356

Query: 1162 LAKALAGQKD--EXXXXXXXXXXXXXXXXXXVTNEEVQKAATALKGSDHRRATTVSARLD 1335
            L +A+   +D                     V N+ V+K A A++  D  RA     R  
Sbjct: 357  LKRAVIDGRDAAHAALAGSAAAIASRAASRRVHNDSVKKRAAAIRAQDAERAAPYPVRAA 416

Query: 1336 AQQKKLNLPVLPTTTIGSFPQTVELRRVRREYKAKKISEEEYTNAIKEEISKVVKIQEEL 1515
            AQQ +LNLP+LPTTTIGSFPQT E+R+ R +YK  ++    Y   ++ EI+ VV+ QE L
Sbjct: 417  AQQARLNLPLLPTTTIGSFPQTAEIRQARAQYKRGELQALTYLERMRAEIADVVQRQEAL 476

Query: 1516 DIDVLVHGEPERNDMVEYFGEQLSGFTFTANGWVQSYGSRCVKPPIIYGDVSRPNPMTVF 1695
             +D+LVHGE ERNDMVEYFGE L G+ FTANGWVQSYGSRCVKPP+IYGDV RP PMTV 
Sbjct: 477  GLDMLVHGEAERNDMVEYFGELLWGYAFTANGWVQSYGSRCVKPPVIYGDVYRPEPMTVE 536

Query: 1696 WSKMAQSMTARPMKGMLTGPVTILNWSFVRNDQPRFETCYQIALAIKKEVEDLEAGGIQV 1875
            WS+ AQS+TA+PMKGMLTGPVT+L WSFVR+DQPR +T  QIALA++ EV DLEA GI  
Sbjct: 537  WSRYAQSLTAKPMKGMLTGPVTMLQWSFVRDDQPREQTALQIALALRDEVRDLEAAGIAA 596

Query: 1876 IQIDEAALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDTTQIHTHMCYSNFNDIIQSII 2055
            IQIDE A REGLPLR  + A YL+WA   FR++  GV++ TQIHTHMCYS FNDI+ +I 
Sbjct: 597  IQIDEPAFREGLPLRAGDVAVYLEWAARVFRVSASGVRNDTQIHTHMCYSEFNDILPAIA 656

Query: 2056 NMDADVITIENSRSDEKLLSVFREGVVYGAGIGPGVYDIHSPRIPSKEEIADRVNKMLAV 2235
            +MDADVITIE SRS+ +LL  F E   Y   IGPGVYDIHSPR+P  EE+   ++K   V
Sbjct: 657  SMDADVITIETSRSNMELLDAFGE-FAYPNEIGPGVYDIHSPRVPRVEEMEALLDKAAQV 715

Query: 2236 LDTNILWVNPDCGLKTRKYAEVKPALTNMVEAAKQIRAELAKA 2364
            +    LWVNPDCGLKTR + EV+ AL  MVEA +++RA  A A
Sbjct: 716  VPVQRLWVNPDCGLKTRGWPEVEAALRGMVEATRRLRARHAGA 758

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>Q9PB72:METE_XYLFA 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase|
            - Xylella fastidiosa
          Length = 758

 Score =  707 bits (1824), Expect = 0.0
 Identities = 381/760 (50%), Positives = 488/760 (64%), Gaps = 5/760 (0%)
 Frame = +1

Query: 88   VGYPRMGPKRELKFALESFWDGKSSAEDLEKVATDLRASIWKQMAGAGIKYIPSNTFAYY 267
            + +PR+G +RELK ALES W G++ A  L+  A +LRA  W+     G+   PSN F+ Y
Sbjct: 7    LSFPRIGARRELKRALESHWRGETDATQLQHTARELRARHWQLQRDTGVDLPPSNDFSLY 66

Query: 268  DQVLDTTAMLGAVPDRYSWTGGEINLSTYFSMARGNAT----VPAMEMTKWFDTNYHFIV 435
            D VLDT  +  A+P RY        L+ YF+MARG       + A+EMTKWFDTNYH++V
Sbjct: 67   DHVLDTAFLFDAIPQRYRALADADPLAGYFAMARGRQADGIDLHALEMTKWFDTNYHYLV 126

Query: 436  PELGPDTKFSYSSHKAINEYKEAKALGVDTVPVLVGPVSYLLLSKAAKGVEKSFXXXXXX 615
            PEL  D  F+   +K I E++EA ALG+ T PVL+GPVS+LLLSK   G  +        
Sbjct: 127  PELHRDQHFALRGNKPIAEFEEALALGITTRPVLLGPVSFLLLSKTVDGSNR----LDLL 182

Query: 616  XXXXXVYKEVIAELKAAGASWIQFDEPTLVKDPESHQLAAFSAAYTELESTLSGLNVLVE 795
                 VY +++ +L+A+GA W+Q DEPTLV D ++    AF  AY  L        +L+ 
Sbjct: 183  ERLLPVYTQLLRQLQASGAEWVQIDEPTLVLDLDAQTQQAFRKAYAALNQGPRP-KLLLT 241

Query: 796  TYFADVPAESYKTLTSLSSVTAYGFDLERGTKTLELVKSGFPAGKYLFAGVVDGRYIWAD 975
            +YF   P      L           DL RGT+ L+ V +  PAG+ L AG+V+GR IW  
Sbjct: 242  SYFG--PLGDNLELALQLPADGLHIDLVRGTEQLDAVLNTLPAGRVLSAGLVNGRNIWRT 299

Query: 976  DLAASLATLQSLEAIVGKDKLVVSTSCSLMHTAVDLVNETKLDDEIKSWLAFAAQKVVEV 1155
             L  +L   +  +  +GKD + ++ SCSL+H  VDL  E  LD ++++WLAFA QK+ E+
Sbjct: 300  ALDNALTLARYAQGRIGKDHVWLAPSCSLLHVPVDLEQEKNLDADVRNWLAFAKQKLSEL 359

Query: 1156 NALAKALAGQKD-EXXXXXXXXXXXXXXXXXXVTNEEVQKAATALKGSDHRRATTVSARL 1332
              LA AL  + + E                  V   EV +   AL     +R T    R 
Sbjct: 360  RVLADALDNKPEAETALTQTRQALEARRQSPKVHRPEVAQRLAALTPDTTQRNTAYPQRS 419

Query: 1333 DAQQKKLNLPVLPTTTIGSFPQTVELRRVRREYKAKKISEEEYTNAIKEEISKVVKIQEE 1512
             AQQ+ LNLP  PTTTIGSFPQT+E+R  R ++K+ K+SE +Y   +K E  + ++ QEE
Sbjct: 420  QAQQQTLNLPAYPTTTIGSFPQTLEVREARAQFKSGKLSESDYETFLKAETERCIRTQEE 479

Query: 1513 LDIDVLVHGEPERNDMVEYFGEQLSGFTFTANGWVQSYGSRCVKPPIIYGDVSRPNPMTV 1692
            + +DVLVHGE ERNDMVEYFGEQL GF FT  GWVQSYGSRCVKPPIIYGDV RP PMTV
Sbjct: 480  IGLDVLVHGEFERNDMVEYFGEQLDGFIFTKLGWVQSYGSRCVKPPIIYGDVVRPAPMTV 539

Query: 1693 FWSKMAQSMTARPMKGMLTGPVTILNWSFVRNDQPRFETCYQIALAIKKEVEDLEAGGIQ 1872
             WS  AQS+T +PMKGMLTGPVT+L WSFVR+DQ R +TC QIALA++ EV+DLE  GI+
Sbjct: 540  TWSAYAQSLTDKPMKGMLTGPVTMLQWSFVRDDQERAQTCRQIALALRDEVQDLEKAGIK 599

Query: 1873 VIQIDEAALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDTTQIHTHMCYSNFNDIIQSI 2052
            VIQIDE A+REGLPLR+ E A YL+WAV SFRI +  V+DTTQIHTHMCYS FNDII+++
Sbjct: 600  VIQIDEPAIREGLPLRRGEWADYLNWAVESFRIASSNVRDTTQIHTHMCYSEFNDIIEAV 659

Query: 2053 INMDADVITIENSRSDEKLLSVFREGVVYGAGIGPGVYDIHSPRIPSKEEIADRVNKMLA 2232
              +DADVI+IE SRS  +LL  F +   Y   IGPGVYDIHSPR+P +EE+   + K  A
Sbjct: 660  AALDADVISIETSRSRMELLDAFVK-FRYPNAIGPGVYDIHSPRVPQEEEMVLLLKKARA 718

Query: 2233 VLDTNILWVNPDCGLKTRKYAEVKPALTNMVEAAKQIRAE 2352
            VL    LWVNPDCGLKTR + E + AL  MV AA+++RAE
Sbjct: 719  VLPPEQLWVNPDCGLKTRGWKETRAALQTMVHAAQRLRAE 758

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>Q98A73:METE_RHILO 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase|
            - Rhizobium loti (Mesorhizobium loti)
          Length = 776

 Score =  697 bits (1799), Expect = 0.0
 Identities = 382/779 (49%), Positives = 486/779 (62%), Gaps = 20/779 (2%)
 Frame = +1

Query: 88   VGYPRMGPKRELKFALESFWDGKSSAEDLEKVATDLRASIWKQMAGAGIKYIPSNTFAYY 267
            +G PR+G +RELKFALES+W GKS A DL   A  LRA+ W++    G+  IPSN F+ Y
Sbjct: 4    LGVPRIGRRRELKFALESYWSGKSPAADLLATAKALRAASWREQHDRGVSKIPSNDFSLY 63

Query: 268  DQVLDTTAMLGAVPDRYSWTGGEINLSTYFSMARGNAT------------------VPAM 393
            D VLDT AM+GAVP RY+WT GE+ L TYF+MARGN                    + AM
Sbjct: 64   DHVLDTVAMVGAVPARYTWTDGEVPLDTYFAMARGNQDQAADCGHAGDEHAANGHGLAAM 123

Query: 394  EMTKWFDTNYHFIVPELGPDTKFSYSSHKAINEYKEAKALGVDTVPVLVGPVSYLLLSKA 573
            EMTKWFDTNYH+IVPEL  D  F+ SS K ++ + EAKALG+ T PVL+GPV++L   K 
Sbjct: 124  EMTKWFDTNYHYIVPELTDDQSFALSSAKPVDHFLEAKALGIHTRPVLLGPVTFL---KL 180

Query: 574  AKGVEKSFXXXXXXXXXXXVYKEVIAELKAAGASWIQFDEPTLVKDPESHQLAAFSAAYT 753
            AK  E+ F           VY+E++  LK AGA W+Q DEP LV D   ++  A   AY 
Sbjct: 181  AKSPEEGFNPIALLPRLLPVYEELLRRLKLAGADWVQIDEPALVVDLVPNERDALQFAYC 240

Query: 754  ELESTLSGLNVLVETYFADVPAESYKTLTSLSSVTAYGFDLERGTKTLELVKSGFPAGKY 933
             L      L ++V  YF  +  ++ +T  SL  V     DL R  + LE V         
Sbjct: 241  RLSKAAPELKIMVAIYFGSL-GDNLETAISLP-VAGLHVDLVRAPEQLETVGRLAQKDLV 298

Query: 934  LFAGVVDGRYIWADDLAASLATLQSLEAIVGKDKLVVSTSCSLMHTAVDLVNETKLDDEI 1113
            L  G++DGR +W  +L A L  ++ + A    D++ ++ SCS++H  +DL  ET LD ++
Sbjct: 299  LSLGLIDGRNVWRANLPAILDRIKPIVAGWPLDRVEIAPSCSMLHVPIDLDMETALDADV 358

Query: 1114 KSWLAFAAQKVVEVNALAKALAGQKDEXXXXXXXXXXXXXXXXXX--VTNEEVQKAATAL 1287
            KSWLAFAAQK  E+  LA+ALA  +D                     V +  V+    ++
Sbjct: 359  KSWLAFAAQKTDELVVLARALAEGRDAVAAELEASAEAAAARATSAKVHDPLVEGRVASI 418

Query: 1288 KGSDHRRATTVSARLDAQQKKLNLPVLPTTTIGSFPQTVELRRVRREYKAKKISEEEYTN 1467
            K +  RR +    R   Q     LP  PTTTIGSFPQT E+R+ R  +   ++S  +Y  
Sbjct: 419  KVAMTRRKSAFDVRSKLQGDTFGLPSFPTTTIGSFPQTAEVRKARAAHAKGELSYVDYEA 478

Query: 1468 AIKEEISKVVKIQEELDIDVLVHGEPERNDMVEYFGEQLSGFTFTANGWVQSYGSRCVKP 1647
             +K+EI   V+ QEE+ +DVLVHGE ERNDMV+YF EQL GF FT +GWVQSYGSR V+P
Sbjct: 479  FLKKEIEAAVRWQEEIGLDVLVHGEFERNDMVQYFAEQLRGFAFTQHGWVQSYGSRFVRP 538

Query: 1648 PIIYGDVSRPNPMTVFWSKMAQSMTARPMKGMLTGPVTILNWSFVRNDQPRFETCYQIAL 1827
            PII GDVSR NPMT+ W + AQS+T +P+KGMLTGPVTILNWSFVR+D PR   C Q+AL
Sbjct: 539  PIIIGDVSRQNPMTLHWWRYAQSLTPKPVKGMLTGPVTILNWSFVRDDLPRSAVCRQVAL 598

Query: 1828 AIKKEVEDLEAGGIQVIQIDEAALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDTTQIH 2007
            AI+ EV DLE  G ++IQIDEAALREGLPLR+++   YLDWAV  FR+ +  V D TQIH
Sbjct: 599  AIRDEVSDLEKAGAKMIQIDEAALREGLPLREADWQAYLDWAVECFRLASTAVGDATQIH 658

Query: 2008 THMCYSNFNDIIQSIINMDADVITIENSRSDEKLLSVFREGVVYGAGIGPGVYDIHSPRI 2187
            THMCYS F DI+ +I  MDADVI+IE SRS  +LL   R    Y   IGPGVYDIHSPR+
Sbjct: 659  THMCYSEFGDIVDAIAAMDADVISIETSRSQLELLDTLRT-FKYPNEIGPGVYDIHSPRV 717

Query: 2188 PSKEEIADRVNKMLAVLDTNILWVNPDCGLKTRKYAEVKPALTNMVEAAKQIRAELAKA 2364
            P   EI++ +      L    LWVNPDCGLKTR++ EV+PAL NMV AA+ IR +   A
Sbjct: 718  PEVGEISNLIMLARKRLSDGQLWVNPDCGLKTRRWEEVRPALVNMVAAARAIRQKAQTA 776

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>Q9F187:METE_RALEU 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase|
            - Ralstonia eutropha (Alcaligenes eutrophus)
          Length = 792

 Score =  690 bits (1780), Expect = 0.0
 Identities = 376/763 (49%), Positives = 486/763 (63%), Gaps = 3/763 (0%)
 Frame = +1

Query: 79   SHIVGYPRMGPKRELKFALESFWDGKSSAEDLEKVATDLRASIWKQMAGAGIKYIPSNTF 258
            +HI+G+PR+G +RELKFA E+FW G  +  +L  VA  LR   W+  A  G+  + +  F
Sbjct: 4    THILGFPRIGERRELKFAQEAFWRGDRTEAELRDVAAQLRRRHWQLQADRGLDTVATGDF 63

Query: 259  AYYDQVLDTTAMLGAVPDRYSWTGGEINLSTYFSMARGNATVPAMEMTKWFDTNYHFIVP 438
            AYYDQ+L  TA+LGA+P R+      + L+ YF +ARGN   PAMEMTKWFDTNYH++VP
Sbjct: 64   AYYDQMLSLTALLGALPRRFGLDPARLTLTQYFELARGNREQPAMEMTKWFDTNYHYLVP 123

Query: 439  ELGPDTKFSYSSHKAINEYKEAKALGVDTVPVLVGPVSYLLLSKAAKGVEKSFXXXXXXX 618
            EL  +T F         E  EA ALG+   PVL+GPV+YL LSK+       F       
Sbjct: 124  ELDAETTFDGGPAWFFEEADEALALGLRARPVLIGPVTYLWLSKSHVA---GFDRLALLP 180

Query: 619  XXXXVYKEVIAELKAAGASWIQFDEPTLVKDPESHQLAAFSAAYTELESTLSGLNVLVET 798
                 Y+ ++ +LKA G  W+Q DEP L  D E   L AF  AY  L    +G  +L+ T
Sbjct: 181  QLLQGYRRILDQLKARGIEWVQIDEPALCLDLEPAWLDAFDTAYAALRE--AGPKLLLAT 238

Query: 799  YFADVPAESYKTLTSLSSVTAYGFDLERGTKTLELVKSGFPAGKYLFAGVVDGRYIWADD 978
            YF D  A+  +   +L  V  +  DL R  + L   ++  PA   L  GV+DGR IW  D
Sbjct: 239  YF-DTAADHAQRAAALP-VDGFHIDLVRAPEQLAAWQAALPAHAVLSLGVIDGRNIWRTD 296

Query: 979  LAASLATLQSLEAIVGKDKLVVSTSCSLMHTAVDLVNETKLDDEIKSWLAFAAQKVVEVN 1158
            L   L TL+ ++A +G ++L ++ SCSL+H  V L +E +LD E+KSWLAFA +K+ E++
Sbjct: 297  LRRVLDTLRPVQAALG-ERLWLAPSCSLLHVPVSLAHEVRLDVELKSWLAFATEKLDELS 355

Query: 1159 ALAKALAGQKDEXXXXXXXXXXXXXXXXXX---VTNEEVQKAATALKGSDHRRATTVSAR 1329
             L +AL  Q D                      V    VQ+   A+      RA+  + R
Sbjct: 356  VLGRAL-NQSDAVVAEALAASDAAQASRRASRRVVKPRVQQRLAAVSAGMADRASPFAER 414

Query: 1330 LDAQQKKLNLPVLPTTTIGSFPQTVELRRVRREYKAKKISEEEYTNAIKEEISKVVKIQE 1509
            ++ Q++ L LP+LPTTTIGSFPQT  +R+ R  +K  +I   EY   I+ EI+  V+ QE
Sbjct: 415  IERQRQALQLPLLPTTTIGSFPQTAAIRQTRAAFKRGEIGALEYLERIRAEIAVAVRKQE 474

Query: 1510 ELDIDVLVHGEPERNDMVEYFGEQLSGFTFTANGWVQSYGSRCVKPPIIYGDVSRPNPMT 1689
             L +DVLVHGE ERNDMVEYFGEQL G+ FT NGWVQSYGSRCVKPP+IYGDV RP PMT
Sbjct: 475  ALGLDVLVHGEAERNDMVEYFGEQLCGYGFTENGWVQSYGSRCVKPPVIYGDVYRPEPMT 534

Query: 1690 VFWSKMAQSMTARPMKGMLTGPVTILNWSFVRNDQPRFETCYQIALAIKKEVEDLEAGGI 1869
            V  ++ AQS+T RPMKGMLTGP+T+L WSFVR+DQPR  T  Q+ALAI+ EV DLE  GI
Sbjct: 535  VDTARYAQSLTERPMKGMLTGPITMLQWSFVRDDQPRATTARQLALAIRDEVCDLEQAGI 594

Query: 1870 QVIQIDEAALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDTTQIHTHMCYSNFNDIIQS 2049
            +VIQIDE ALREGLPLR+++   YLDWAV +FR++  GVQD TQIHTHMCY+ FNDI+ +
Sbjct: 595  RVIQIDEPALREGLPLRRADWDAYLDWAVTAFRLSASGVQDQTQIHTHMCYAEFNDILPA 654

Query: 2050 IINMDADVITIENSRSDEKLLSVFREGVVYGAGIGPGVYDIHSPRIPSKEEIADRVNKML 2229
            I  MDADVITIE SRS  +LL  F +   Y   IGPGVYDIHSPR+PS + +   +++  
Sbjct: 655  IAAMDADVITIETSRSAMELLEGFGD-FDYPNEIGPGVYDIHSPRVPSVQAMERLLDRAC 713

Query: 2230 AVLDTNILWVNPDCGLKTRKYAEVKPALTNMVEAAKQIRAELA 2358
             V+    LWVNPDCGLKTR + E + AL NMV AA+ +RA L+
Sbjct: 714  EVVPPQRLWVNPDCGLKTRGWEETEAALANMVSAARALRARLS 756

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>Q7NS23:METE_CHRVO 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase|
            - Chromobacterium violaceum
          Length = 760

 Score =  689 bits (1777), Expect = 0.0
 Identities = 378/765 (49%), Positives = 482/765 (63%), Gaps = 2/765 (0%)
 Frame = +1

Query: 76   ASHIVGYPRMGPKRELKFALESFWDGKSSAEDLEKVATDLRASIWKQMAGAGIKYIPSNT 255
            A+H++G+PR+G KRELK  LE +W  +     L + A +LR   W    GAG++  P   
Sbjct: 4    ATHLLGFPRIGAKRELKTLLERYWKQELDEAALSQGAKELRQKHWLLQKGAGVELSPVGD 63

Query: 256  FAYYDQVLDTTAMLGAVPDRYSWTGGEINLSTYFSMARGNATVPAMEMTKWFDTNYHFIV 435
            F+ YD VLD   ++GA P R+ +    +    YF +ARGNA  PAMEMTKWFDTNYH++V
Sbjct: 64   FSLYDHVLDAQLLVGAAPARFGFDAAALTTGQYFELARGNAVQPAMEMTKWFDTNYHYLV 123

Query: 436  PELGPDTKFSYSSHKAINEYKEAKALGVDTVPVLVGPVSYLLLSKAAKGVEKSFXXXXXX 615
            PE   DT FS    + +++ +EA+ALGV   PVL+GP+S L L KA KG  + F      
Sbjct: 124  PEWHADTAFSAQPERLLSQLREARALGVAAKPVLLGPLSLLWLGKA-KG--RPFDRLALL 180

Query: 616  XXXXXVYKEVIAELKAAGASWIQFDEPTLVKDPESHQLAAFSAAYTELESTLSGLNVLVE 795
                  Y+E+++ L+AAGA W Q DEP L  D E   L AF+ AY +L      L  L+ 
Sbjct: 181  PGLVAAYRELLSSLRAAGAEWAQIDEPILALDLEPSWLDAFAPAYAQLSRHAPKL--LLA 238

Query: 796  TYFADVPAESYKTLTSLSSVTAYGFDLERGTKTLELVKSGFPAGKYLFAGVVDGRYIWAD 975
            TYF DV +E    L SL  V     DL R  + +      +PA K L AG+VDGR IW  
Sbjct: 239  TYFGDV-SEHAARLKSLP-VAGLHLDLVRAPEQISAFLPDYPADKVLSAGIVDGRNIWRA 296

Query: 976  DLAASLATLQSLEAIVGKDKLVVSTSCSLMHTAVDLVNETKLDDEIKSWLAFAAQKVVEV 1155
            DL+A L  L  L   +G D+L ++ SCSL+H+  D   ET LD E+K+WLAFA QK+ E+
Sbjct: 297  DLSALLDRLAPLAQQLG-DRLWLAPSCSLLHSPFDAAAETGLDPELKNWLAFAVQKLNEL 355

Query: 1156 NALAKALAGQKDEXXXXXXXXXXXXXXXXXX--VTNEEVQKAATALKGSDHRRATTVSAR 1329
              L + L   +                      + +  V +   AL     RRA+    R
Sbjct: 356  KTLKRGLEHGRSAIAGELSGSDFAREQRRASPRIHDPAVARRLAALPEGTDRRASPYPIR 415

Query: 1330 LDAQQKKLNLPVLPTTTIGSFPQTVELRRVRREYKAKKISEEEYTNAIKEEISKVVKIQE 1509
             + QQ  L LP LPTTTIGSFPQT  +R  R  +K  ++S   Y  A+++EI   ++ QE
Sbjct: 416  AERQQAWLKLPPLPTTTIGSFPQTPAIRASRAAFKKGELSAAGYRQAMEKEIELAIRRQE 475

Query: 1510 ELDIDVLVHGEPERNDMVEYFGEQLSGFTFTANGWVQSYGSRCVKPPIIYGDVSRPNPMT 1689
             L +DVLVHGE ERNDMVEYFGEQL+GF FTA GWVQSYGSRCVKPPII+GDV+RP PMT
Sbjct: 476  ALGLDVLVHGEAERNDMVEYFGEQLAGFAFTAGGWVQSYGSRCVKPPIIFGDVARPKPMT 535

Query: 1690 VFWSKMAQSMTARPMKGMLTGPVTILNWSFVRNDQPRFETCYQIALAIKKEVEDLEAGGI 1869
            V W++ AQS+TA+P+KGMLTGPVTIL WSFVR+D PR E C QIALA+  EV DLEA GI
Sbjct: 536  VDWARYAQSLTAKPVKGMLTGPVTILQWSFVRDDLPRREVCRQIALALNDEVLDLEAAGI 595

Query: 1870 QVIQIDEAALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDTTQIHTHMCYSNFNDIIQS 2049
            +VIQIDE A+REGLPL+++    YL WA  +FR+++ GV D TQIHTHMCYS F DI+ +
Sbjct: 596  RVIQIDEPAIREGLPLKRAGRDVYLAWAGEAFRLSSRGVDDATQIHTHMCYSEFGDILPA 655

Query: 2050 IINMDADVITIENSRSDEKLLSVFREGVVYGAGIGPGVYDIHSPRIPSKEEIADRVNKML 2229
            I  +DADVITIE SRSD  LL+ F     Y   IGPGVYDIHSPR+PS  EI   ++K L
Sbjct: 656  IAALDADVITIETSRSDMALLADFGR-FRYPNAIGPGVYDIHSPRVPSAAEIRALLDKAL 714

Query: 2230 AVLDTNILWVNPDCGLKTRKYAEVKPALTNMVEAAKQIRAELAKA 2364
             V+    LWVNPDCGLKTR + EV+ AL  MV   +++R +LA+A
Sbjct: 715  RVIPAERLWVNPDCGLKTRGWPEVEAALAAMVAVGRELREKLAQA 759

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>Q9AMV8:METE_BRAJA 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase|
            - Bradyrhizobium japonicum
          Length = 781

 Score =  688 bits (1776), Expect = 0.0
 Identities = 365/770 (47%), Positives = 490/770 (63%), Gaps = 16/770 (2%)
 Frame = +1

Query: 88   VGYPRMGPKRELKFALESFWDGKSSAEDLEKVATDLRASIWKQMAGAGIKYIPSNTFAYY 267
            +G PR+GP+RELK ALES+W GK S + L + A  LRA+ W +    G+  IPSN F+ Y
Sbjct: 11   LGTPRIGPRRELKLALESYWAGKISEQQLHEDAFGLRAANWARQKSLGVTIIPSNDFSLY 70

Query: 268  DQVLDTTAMLGAVPDRYSWTGGEINLSTYFSMARGN---------------ATVPAMEMT 402
            DQVLDT+ M+GA+P+ Y+  G  ++L TYF+MARG+               + VPA EMT
Sbjct: 71   DQVLDTSVMVGAIPEIYAANGESVSLQTYFAMARGSQCGEQDASCAQSPRGSGVPAQEMT 130

Query: 403  KWFDTNYHFIVPELGPDTKFSYSSHKAINEYKEAKALGVDTVPVLVGPVSYLLLSKAAKG 582
            KWFDTNYH++VPE      F   S K + EY+EA+ALG  T PVL+GPV++L   K  K 
Sbjct: 131  KWFDTNYHYMVPEFYRGQAFRLCSRKPVEEYEEARALGFQTRPVLIGPVTFL---KLGKS 187

Query: 583  VEKSFXXXXXXXXXXXVYKEVIAELKAAGASWIQFDEPTLVKDPESHQLAAFSAAYTELE 762
             + +F           VY +++ EL   GASW+QFDEP LV D +     +   AY    
Sbjct: 188  TDSAFQPLSLLDDLIPVYIDLLHELAKRGASWVQFDEPCLVLDLDEAARNSLLHAYNRFA 247

Query: 763  STLSGLNVLVETYFADVPAESYKTLTSLSSVTAYGFDLERGTKTLELVKSGFPAGKYLFA 942
                 + +++ +YF  +  ++  T  SL  ++    DL R  + L+ + +   +   +  
Sbjct: 248  KEGPAIKIMLASYFGAL-GDNLDTALSLP-ISGLHVDLVRAPELLDQIVADGRSDLVMSL 305

Query: 943  GVVDGRYIWADDLAASLATLQSLEAIVGKDKLVVSTSCSLMHTAVDLVNETKLDDEIKSW 1122
            GV+DGR +W  +L +    L+   A +G+ ++ ++ SCSL+H  VD+  ET L  ++KSW
Sbjct: 306  GVIDGRNVWRSNLPSLRQRLKPSIAKLGRHRVQLAPSCSLLHVPVDVELETGLASDVKSW 365

Query: 1123 LAFAAQKVVEVNALAKALAGQKDEXXXXXXXXXXXXXXXXXX-VTNEEVQKAATALKGSD 1299
            LAF+ QK+ E+  LA+ LAG ++                    + N  V     A+  + 
Sbjct: 366  LAFSVQKMRELAILARVLAGDQNVGLALAESECAATARRTSPKIHNANVAVRMRAIDQTM 425

Query: 1300 HRRATTVSARLDAQQKKLNLPVLPTTTIGSFPQTVELRRVRREYKAKKISEEEYTNAIKE 1479
             +RAT  + R + Q+++  LP  PTTTIGSFPQT  +R  R  +    +SEE+Y   +KE
Sbjct: 426  RQRATPFARRSEIQRERFGLPAFPTTTIGSFPQTTAVRNARAAHARGAMSEEQYDRFLKE 485

Query: 1480 EISKVVKIQEELDIDVLVHGEPERNDMVEYFGEQLSGFTFTANGWVQSYGSRCVKPPIIY 1659
            EI++ V+ QE++ +DVLVHGE ERNDMV+YF EQL+GF FT NGWVQSYGSRCV+PPI++
Sbjct: 486  EIARAVRWQEDIGLDVLVHGEFERNDMVQYFSEQLAGFAFTRNGWVQSYGSRCVRPPILF 545

Query: 1660 GDVSRPNPMTVFWSKMAQSMTARPMKGMLTGPVTILNWSFVRNDQPRFETCYQIALAIKK 1839
            GDV RP P+TV W + AQS+T++PMK MLTGPVTILNWSFVR+D PR E C Q+ALA++ 
Sbjct: 546  GDVVRPKPITVEWWRYAQSLTSKPMKAMLTGPVTILNWSFVRDDIPRSEVCRQLALAMRD 605

Query: 1840 EVEDLEAGGIQVIQIDEAALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDTTQIHTHMC 2019
            EV DLE  G  +IQIDEAALREGLPLR+S+   YLDWA   FRI + GV D TQIHTHMC
Sbjct: 606  EVRDLENAGAAMIQIDEAALREGLPLRRSDWKAYLDWAGDCFRICSSGVTDQTQIHTHMC 665

Query: 2020 YSNFNDIIQSIINMDADVITIENSRSDEKLLSVFREGVVYGAGIGPGVYDIHSPRIPSKE 2199
            YS FNDII +I  MDADVI+IE SRS  +LL  FR    Y   IGPGVYDIHSPR+P  +
Sbjct: 666  YSEFNDIIGAIAAMDADVISIETSRSKMELLDAFRR-YEYPNQIGPGVYDIHSPRVPETD 724

Query: 2200 EIADRVNKMLAVLDTNILWVNPDCGLKTRKYAEVKPALTNMVEAAKQIRA 2349
            E+ + +      L  + LWVNPDCGLKTRK+ EV+PAL NMV AA+++RA
Sbjct: 725  EMKELIVLARTRLQDSQLWVNPDCGLKTRKWEEVRPALANMVAAARELRA 774

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>Q7W791:METE_BORPA 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase|
            - Bordetella parapertussis
          Length = 764

 Score =  684 bits (1766), Expect = 0.0
 Identities = 375/767 (48%), Positives = 488/767 (63%), Gaps = 11/767 (1%)
 Frame = +1

Query: 82   HIVGYPRMGPKRELKFALESFWDGKSSAEDLEKVATDLRASIWKQMAGAGIKYIPSNTFA 261
            H +G+PR+G +RELK A+E++W G+ +AE L +    LRA+ W++ A AG+ ++P   FA
Sbjct: 5    HNLGFPRIGAQRELKRAVEAYWAGRQTAEALHETGRALRAAHWQRQADAGVAFVPVGDFA 64

Query: 262  YYDQVLDTTAMLGAVPDRYSWTGGE-INLSTYFSMARGNAT----VPAMEMTKWFDTNYH 426
            +YD +L+ T +LGAVP R+    G+ ++L T F M RG A       A EMTKWFDTNYH
Sbjct: 65   WYDHILEWTTLLGAVPARFGHPEGKPVDLDTLFRMGRGRAPSGKPAAACEMTKWFDTNYH 124

Query: 427  FIVPELGPDTKFSYSSHKAINEYKEAKALGVDTVPVLVGPVSYLLLSKA---AKGVEKSF 597
            +IVPEL P   F  +      + KEA+ALG    PV+ GP+++L L K    A+G     
Sbjct: 125  YIVPELTPGQTFRVAREDLFEQVKEAQALGHRVKPVIPGPLTWLWLGKGDAFAQGAG-DI 183

Query: 598  XXXXXXXXXXXVYKEVIAELKAAGASWIQFDEPTLVKDPESHQLAAFSAAYTELESTLSG 777
                       VY EV+  L   G  W+Q DEP LV D       A+ A Y +L +  S 
Sbjct: 184  GKLQLLDALLPVYGEVLERLAGLGVEWVQIDEPALVLDLPQAWRDAYQAVYAKLAA--SP 241

Query: 778  LNVLVETYFADVPAESYKTLTSLSSVTAYGFDLERGTKTLELVKSGFPAGKYLFAGVVDG 957
            + +L+ TYF D   ++  T  +L  V     DL R    L  V SG   G+ L AGV++G
Sbjct: 242  VKLLLATYF-DGLKDNLATALALP-VAGLHVDLVRAPDQLSDVASGLRPGQVLSAGVING 299

Query: 958  RYIWADDLAASLATLQSLEAIVGKDKLVVSTSCSLMHTAVDLVNETKLDDEIKSWLAFAA 1137
            R IW  DL A+LA L  +   + +++L ++ SCSL+H  VDL  ET+LD E+  WL+FA 
Sbjct: 300  RNIWRTDLDAALAMLAPVREQL-QERLWLAPSCSLLHVPVDLAGETELDAELLGWLSFAV 358

Query: 1138 QKVVEVNALAKALAGQKD---EXXXXXXXXXXXXXXXXXXVTNEEVQKAATALKGSDHRR 1308
            QK+ E+  L KAL G  D   +                  + N  V +      G    R
Sbjct: 359  QKLDELCLLGKALGGDADPAVQQGLAAQRAALQARRQSPRIHNPAVAQRMAGQAGVSRER 418

Query: 1309 ATTVSARLDAQQKKLNLPVLPTTTIGSFPQTVELRRVRREYKAKKISEEEYTNAIKEEIS 1488
            A     R+  QQ +L LP  PTTTIGSFPQT E+R +RR++K+  +++  Y NAI++EI 
Sbjct: 419  AP-FGQRIARQQSELRLPAFPTTTIGSFPQTAEIRALRRDWKSGALTDSAYENAIRKEIE 477

Query: 1489 KVVKIQEELDIDVLVHGEPERNDMVEYFGEQLSGFTFTANGWVQSYGSRCVKPPIIYGDV 1668
            +V++ QE++ +DVLVHGEPERNDMVEYFGE L+GF FT NGWVQSYGSRCVKPPII+GDV
Sbjct: 478  EVIRFQEKVGLDVLVHGEPERNDMVEYFGELLAGFAFTKNGWVQSYGSRCVKPPIIFGDV 537

Query: 1669 SRPNPMTVFWSKMAQSMTARPMKGMLTGPVTILNWSFVRNDQPRFETCYQIALAIKKEVE 1848
            +RP PMTV WS  AQS+T +P+KGMLTGPVTIL WSFVR+DQPR  TC Q+ALA++ EV 
Sbjct: 538  ARPAPMTVGWSAYAQSLTDKPVKGMLTGPVTILQWSFVRDDQPREATCRQLALALRDEVV 597

Query: 1849 DLEAGGIQVIQIDEAALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDTTQIHTHMCYSN 2028
            DLEA GI+VIQIDE A+REGLPLR+++   YLDWAV  FR++  GV + TQIHTHMCYS 
Sbjct: 598  DLEAAGIRVIQIDEPAIREGLPLRRADWRAYLDWAVDCFRLSTAGVGEATQIHTHMCYSE 657

Query: 2029 FNDIIQSIINMDADVITIENSRSDEKLLSVFREGVVYGAGIGPGVYDIHSPRIPSKEEIA 2208
            FNDII+SI  MDADVITIE SRS+ +LL  F E   Y   IGPGVYDIHSP +P  + + 
Sbjct: 658  FNDIIESIAAMDADVITIETSRSNMELLKAF-EDFHYPNDIGPGVYDIHSPNVPEVDWMV 716

Query: 2209 DRVNKMLAVLDTNILWVNPDCGLKTRKYAEVKPALTNMVEAAKQIRA 2349
            + + K  A L    LWVNPDCGLKTR + E + AL  MV+AA+ +RA
Sbjct: 717  ELMRKAAARLPKERLWVNPDCGLKTRAWPETEAALIGMVQAARTLRA 763

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>Q7WKM7:METE_BORBR 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase|
            - Bordetella bronchiseptica (Alcaligenes bronchisepticus)
          Length = 764

 Score =  684 bits (1766), Expect = 0.0
 Identities = 375/767 (48%), Positives = 488/767 (63%), Gaps = 11/767 (1%)
 Frame = +1

Query: 82   HIVGYPRMGPKRELKFALESFWDGKSSAEDLEKVATDLRASIWKQMAGAGIKYIPSNTFA 261
            H +G+PR+G +RELK A+E++W G+ +AE L +    LRA+ W++ A AG+ ++P   FA
Sbjct: 5    HNLGFPRIGAQRELKRAVEAYWAGRQTAEALHETGRALRAAHWQRQADAGVAFVPVGDFA 64

Query: 262  YYDQVLDTTAMLGAVPDRYSWTGGE-INLSTYFSMARGNAT----VPAMEMTKWFDTNYH 426
            +YD +L+ T +LGAVP R+    G+ ++L T F M RG A       A EMTKWFDTNYH
Sbjct: 65   WYDHILEWTTLLGAVPARFGHPEGKPVDLDTLFRMGRGRAPSGKPAAACEMTKWFDTNYH 124

Query: 427  FIVPELGPDTKFSYSSHKAINEYKEAKALGVDTVPVLVGPVSYLLLSKA---AKGVEKSF 597
            +IVPEL P   F  +      + KEA+ALG    PV+ GP+++L L K    A+G     
Sbjct: 125  YIVPELTPGQTFRVAREDLFEQVKEAQALGHRVKPVIPGPLTWLWLGKGDAFAQGAG-DI 183

Query: 598  XXXXXXXXXXXVYKEVIAELKAAGASWIQFDEPTLVKDPESHQLAAFSAAYTELESTLSG 777
                       VY EV+  L   G  W+Q DEP LV D       A+ A Y +L +  S 
Sbjct: 184  GKLQLLDALLPVYGEVLERLAGLGVEWVQIDEPALVLDLPQAWRDAYQAVYAKLAA--SP 241

Query: 778  LNVLVETYFADVPAESYKTLTSLSSVTAYGFDLERGTKTLELVKSGFPAGKYLFAGVVDG 957
            + +L+ TYF D   ++  T  +L  V     DL R    L  V SG   G+ L AGV++G
Sbjct: 242  VKLLLATYF-DGLKDNLATALALP-VAGLHVDLVRAPDQLSDVASGLRPGQVLSAGVING 299

Query: 958  RYIWADDLAASLATLQSLEAIVGKDKLVVSTSCSLMHTAVDLVNETKLDDEIKSWLAFAA 1137
            R IW  DL A+LA L  +   + +++L ++ SCSL+H  VDL  ET+LD E+  WL+FA 
Sbjct: 300  RNIWRTDLDAALAMLAPVREQL-QERLWLAPSCSLLHVPVDLAGETELDAELLGWLSFAV 358

Query: 1138 QKVVEVNALAKALAGQKD---EXXXXXXXXXXXXXXXXXXVTNEEVQKAATALKGSDHRR 1308
            QK+ E+  L KAL G  D   +                  + N  V +      G    R
Sbjct: 359  QKLDELCLLGKALGGDADPAVQQGLAAQRAALQARRQSPRIHNPAVAQRMAGQAGVSRER 418

Query: 1309 ATTVSARLDAQQKKLNLPVLPTTTIGSFPQTVELRRVRREYKAKKISEEEYTNAIKEEIS 1488
            A     R+  QQ +L LP  PTTTIGSFPQT E+R +RR++K+  +++  Y NAI++EI 
Sbjct: 419  AP-FGQRIARQQSELRLPAFPTTTIGSFPQTAEIRALRRDWKSGALTDSAYENAIRKEIE 477

Query: 1489 KVVKIQEELDIDVLVHGEPERNDMVEYFGEQLSGFTFTANGWVQSYGSRCVKPPIIYGDV 1668
            +V++ QE++ +DVLVHGEPERNDMVEYFGE L+GF FT NGWVQSYGSRCVKPPII+GDV
Sbjct: 478  EVIRFQEKVGLDVLVHGEPERNDMVEYFGELLAGFAFTKNGWVQSYGSRCVKPPIIFGDV 537

Query: 1669 SRPNPMTVFWSKMAQSMTARPMKGMLTGPVTILNWSFVRNDQPRFETCYQIALAIKKEVE 1848
            +RP PMTV WS  AQS+T +P+KGMLTGPVTIL WSFVR+DQPR  TC Q+ALA++ EV 
Sbjct: 538  ARPAPMTVGWSAYAQSLTDKPVKGMLTGPVTILQWSFVRDDQPREATCRQLALALRDEVV 597

Query: 1849 DLEAGGIQVIQIDEAALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDTTQIHTHMCYSN 2028
            DLEA GI+VIQIDE A+REGLPLR+++   YLDWAV  FR++  GV + TQIHTHMCYS 
Sbjct: 598  DLEAAGIRVIQIDEPAIREGLPLRRADWRAYLDWAVDCFRLSTAGVGEATQIHTHMCYSE 657

Query: 2029 FNDIIQSIINMDADVITIENSRSDEKLLSVFREGVVYGAGIGPGVYDIHSPRIPSKEEIA 2208
            FNDII+SI  MDADVITIE SRS+ +LL  F E   Y   IGPGVYDIHSP +P  + + 
Sbjct: 658  FNDIIESIAAMDADVITIETSRSNMELLKAF-EDFHYPNDIGPGVYDIHSPNVPEVDWMV 716

Query: 2209 DRVNKMLAVLDTNILWVNPDCGLKTRKYAEVKPALTNMVEAAKQIRA 2349
            + + K  A L    LWVNPDCGLKTR + E + AL  MV+AA+ +RA
Sbjct: 717  ELMRKAAARLPKERLWVNPDCGLKTRAWPETEAALIGMVQAARTLRA 763

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>Q7VVU3:METE_BORPE 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase|
            - Bordetella pertussis
          Length = 764

 Score =  684 bits (1765), Expect = 0.0
 Identities = 375/767 (48%), Positives = 488/767 (63%), Gaps = 11/767 (1%)
 Frame = +1

Query: 82   HIVGYPRMGPKRELKFALESFWDGKSSAEDLEKVATDLRASIWKQMAGAGIKYIPSNTFA 261
            H +G+PR+G +RELK A+E++W G+ +AE L +    LRA+ W++ A AG+ ++P   FA
Sbjct: 5    HNLGFPRIGAQRELKRAVEAYWAGRQTAEALHETGRALRAAHWQRQADAGVAFVPVGDFA 64

Query: 262  YYDQVLDTTAMLGAVPDRYSWTGGE-INLSTYFSMARGNAT----VPAMEMTKWFDTNYH 426
            +YD +L+ T +LGAVP R+    G+ ++L T F M RG A       A EMTKWFDTNYH
Sbjct: 65   WYDHILEWTTLLGAVPARFGHPEGKPVDLDTLFRMGRGRAPSGKPAAACEMTKWFDTNYH 124

Query: 427  FIVPELGPDTKFSYSSHKAINEYKEAKALGVDTVPVLVGPVSYLLLSKA---AKGVEKSF 597
            +IVPEL P   F  +      + KEA+ALG    PV+ GP+++L L K    A+G     
Sbjct: 125  YIVPELTPGQTFRVAREDLFEQVKEAQALGHRVKPVIPGPLTWLWLGKGDAFAQGAG-DI 183

Query: 598  XXXXXXXXXXXVYKEVIAELKAAGASWIQFDEPTLVKDPESHQLAAFSAAYTELESTLSG 777
                       VY EV+  L   G  W+Q DEP LV D       A+ A Y +L +  S 
Sbjct: 184  GKLQLLDALLPVYGEVLERLAGLGVEWVQIDEPALVLDLPQAWRDAYQAVYAKLAA--SP 241

Query: 778  LNVLVETYFADVPAESYKTLTSLSSVTAYGFDLERGTKTLELVKSGFPAGKYLFAGVVDG 957
            + +L+ TYF D   ++  T  +L  V     DL R    L  V SG   G+ L AGV++G
Sbjct: 242  VKLLLATYF-DGLKDNLATALALP-VAGLHVDLVRAPDQLSDVASGLRPGQVLSAGVING 299

Query: 958  RYIWADDLAASLATLQSLEAIVGKDKLVVSTSCSLMHTAVDLVNETKLDDEIKSWLAFAA 1137
            R IW  DL A+LA L  +   + +++L ++ SCSL+H  VDL  ET+LD E+  WL+FA 
Sbjct: 300  RNIWRTDLDAALAMLVPVREQL-QERLWLAPSCSLLHVPVDLAGETELDAELLGWLSFAV 358

Query: 1138 QKVVEVNALAKALAGQKD---EXXXXXXXXXXXXXXXXXXVTNEEVQKAATALKGSDHRR 1308
            QK+ E+  L KAL G  D   +                  + N  V +      G    R
Sbjct: 359  QKLDELCLLGKALGGDADPAVQQGLAAQRAALQARRQSPRIHNPAVAQRMAGQAGVSRER 418

Query: 1309 ATTVSARLDAQQKKLNLPVLPTTTIGSFPQTVELRRVRREYKAKKISEEEYTNAIKEEIS 1488
            A     R+  QQ +L LP  PTTTIGSFPQT E+R +RR++K+  +++  Y NAI++EI 
Sbjct: 419  AP-FGQRIARQQSELRLPAFPTTTIGSFPQTAEIRALRRDWKSGALTDSAYENAIRKEIE 477

Query: 1489 KVVKIQEELDIDVLVHGEPERNDMVEYFGEQLSGFTFTANGWVQSYGSRCVKPPIIYGDV 1668
            +V++ QE++ +DVLVHGEPERNDMVEYFGE L+GF FT NGWVQSYGSRCVKPPII+GDV
Sbjct: 478  EVIRFQEKVGLDVLVHGEPERNDMVEYFGELLAGFAFTKNGWVQSYGSRCVKPPIIFGDV 537

Query: 1669 SRPNPMTVFWSKMAQSMTARPMKGMLTGPVTILNWSFVRNDQPRFETCYQIALAIKKEVE 1848
            +RP PMTV WS  AQS+T +P+KGMLTGPVTIL WSFVR+DQPR  TC Q+ALA++ EV 
Sbjct: 538  ARPAPMTVGWSAYAQSLTDKPVKGMLTGPVTILQWSFVRDDQPREATCRQLALALRDEVV 597

Query: 1849 DLEAGGIQVIQIDEAALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDTTQIHTHMCYSN 2028
            DLEA GI+VIQIDE A+REGLPLR+++   YLDWAV  FR++  GV + TQIHTHMCYS 
Sbjct: 598  DLEAAGIRVIQIDEPAIREGLPLRRADWRAYLDWAVDCFRLSTAGVGEATQIHTHMCYSE 657

Query: 2029 FNDIIQSIINMDADVITIENSRSDEKLLSVFREGVVYGAGIGPGVYDIHSPRIPSKEEIA 2208
            FNDII+SI  MDADVITIE SRS+ +LL  F E   Y   IGPGVYDIHSP +P  + + 
Sbjct: 658  FNDIIESIAAMDADVITIETSRSNMELLKAF-EDFHYPNDIGPGVYDIHSPNVPEVDWMV 716

Query: 2209 DRVNKMLAVLDTNILWVNPDCGLKTRKYAEVKPALTNMVEAAKQIRA 2349
            + + K  A L    LWVNPDCGLKTR + E + AL  MV+AA+ +RA
Sbjct: 717  ELMRKAAARLPKERLWVNPDCGLKTRAWPETEAALIGMVQAARTLRA 763

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>Q93J59:METE_STRCO 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase|
            - Streptomyces coelicolor
          Length = 772

 Score =  683 bits (1762), Expect = 0.0
 Identities = 368/763 (48%), Positives = 476/763 (62%), Gaps = 5/763 (0%)
 Frame = +1

Query: 85   IVGYPRMGPKRELKFALESFWDGKSSAEDLEKVATDLRASIWKQMAGAGIKYIPSNTFAY 264
            + GYPR GP RELK A+E +W G+ SA +L  +A DLRA+ W+++A AGI  +P+  F+Y
Sbjct: 14   VYGYPRQGPNRELKKAIEGYWKGRVSAPELRSLAADLRAANWRRLADAGIDEVPAGDFSY 73

Query: 265  YDQVLDTTAMLGAVPDRYSWTGGEINLSTYFSMARGNATVPAMEMTKWFDTNYHFIVPEL 444
            YD VLDTT M+GA+P+R+        L  YF+MARG   V  +EMTKWFDTNYH++VPEL
Sbjct: 74   YDHVLDTTVMVGAIPERHRAAVAADALDGYFAMARGTQEVAPLEMTKWFDTNYHYLVPEL 133

Query: 445  GPDTKFSYSSHKAINEYKEAKALGVDTVPVLVGPVSYLLLSKAAKGVEKSFXXXXXXXXX 624
            GPDT F+  S K + E  EA ALG+   PVLVGPV+YLLL+K A G    F         
Sbjct: 134  GPDTVFTADSTKQVTELAEAVALGLTARPVLVGPVTYLLLAKPAPGAPADFEPLTLLDRL 193

Query: 625  XXVYKEVIAELKAAGASWIQFDEPTLVKDPESHQLAAFSAAYTELESTLSGLNVLVETYF 804
              VY EV+ +L+AAGA W+Q DEP  V+D    +L A   AY EL +      +LV +YF
Sbjct: 194  LPVYAEVLTDLRAAGAEWVQLDEPAFVQDRTPAELNALERAYRELGALTDRPKLLVASYF 253

Query: 805  ADVPAESYKTLTSLS-SVTAYGFDLERGTKTLELVKSGFPAGKYLFAGVVDGRYIWADDL 981
             D   ++   L        A  F     T    L   G   GK L AGVV+GR IW +DL
Sbjct: 254  -DRLGDALPVLAKAPIEGLALDFTDAAATNLDALAAVGGLPGKRLVAGVVNGRNIWINDL 312

Query: 982  AASLATLQSLEAIVGKDKLVVSTSCSLMHTAVDLVNETKLDDEIKSWLAFAAQKVVEVNA 1161
              SL+TL +L  +   D++ VS SCSL+H  +D   E  ++ +I  WLAFA QK  E+  
Sbjct: 313  QKSLSTLGTLLGLA--DRVDVSASCSLLHVPLDTGAERDIEPQILRWLAFARQKTAEIVT 370

Query: 1162 LAKALAGQKDEXXXXXXXXXXXXXXXXXX--VTNEEVQKAATALKGSDHRRATTVSARLD 1335
            LAK LA   D                       N  V+  A A+   D RR+   + R  
Sbjct: 371  LAKGLAQGTDAITGELAASRADMASRAGSPITRNPAVRARAEAVTDDDARRSQPYAERTA 430

Query: 1336 AQQKKLNLPVLPTTTIGSFPQTVELRRVRREYKAKKISEEEYTNAIKEEISKVVKIQEEL 1515
            AQ+  L LP LPTTTIGSFPQT E+R  R + +  +I    Y   I+ EI +V+  QE+ 
Sbjct: 431  AQRAHLGLPPLPTTTIGSFPQTGEIRAARADLRDGRIDIAGYEERIRAEIQEVISFQEKT 490

Query: 1516 DIDVLVHGEPERNDMVEYFGEQLSGFTFTANGWVQSYGSRCVKPPIIYGDVSRPNPMTVF 1695
             +DVLVHGEPERNDMV+YF EQL+G+  T +GWVQSYG+R V+PPI+ GD+SRP PMTV 
Sbjct: 491  GLDVLVHGEPERNDMVQYFAEQLTGYLATQHGWVQSYGTRYVRPPILAGDISRPEPMTVR 550

Query: 1696 WSKMAQSMTARPMKGMLTGPVTILNWSFVRNDQPRFETCYQIALAIKKEVEDLEAGGIQV 1875
            W+  AQS+T +P+KGMLTGPVT+L WSFVR+DQP  +T  Q+ALA++ EV DLEA G  V
Sbjct: 551  WTTYAQSLTEKPVKGMLTGPVTMLAWSFVRDDQPLGDTARQVALALRDEVNDLEAAGTSV 610

Query: 1876 IQIDEAALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDTTQIHTHMCYSNFNDIIQSII 2055
            IQ+DE ALRE LPLR ++H  YL WA  +FR+T  GV+  TQIHTHMCY+ F DI+Q+I 
Sbjct: 611  IQVDEPALRETLPLRAADHTAYLAWATEAFRLTTSGVRPDTQIHTHMCYAEFGDIVQAID 670

Query: 2056 NMDADVITIENSRSDEKLLSVFREGVVYG--AGIGPGVYDIHSPRIPSKEEIADRVNKML 2229
            ++DADVI++E +RS    + V  E   +G     GPGVYDIHSPR+PS EE A  +   L
Sbjct: 671  DLDADVISLEAARSH---MQVAHELATHGYPREAGPGVYDIHSPRVPSAEEAAALLRTGL 727

Query: 2230 AVLDTNILWVNPDCGLKTRKYAEVKPALTNMVEAAKQIRAELA 2358
              +    LWVNPDCGLKTR + E + +L N+V  A+ +R EL+
Sbjct: 728  KAIPAERLWVNPDCGLKTRGWPETRASLENLVATARTLRGELS 770

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>Q82UP6:METE_NITEU 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase|
            - Nitrosomonas europaea
          Length = 758

 Score =  680 bits (1754), Expect = 0.0
 Identities = 363/762 (47%), Positives = 478/762 (62%), Gaps = 3/762 (0%)
 Frame = +1

Query: 79   SHIVGYPRMGPKRELKFALESFWDGKSSAEDLEKVATDLRASIWKQMAGAGIKYIPSNTF 258
            +H +G+PR+G +RELK ALE++W G++  + L   A  +R   W     AGI  IP   F
Sbjct: 5    THNLGFPRIGAQRELKKALETYWKGQNDVDQLLATARAIRTGNWLLQQKAGIDLIPVGDF 64

Query: 259  AYYDQVLDTTAMLGAVPDRYSWTGGEINLSTYFSMARGNATVPAMEMTKWFDTNYHFIVP 438
            + YD +LD T +LGA+P R+  TG +I+   YF+MARG A  PAMEMTKWF+TNYH+IVP
Sbjct: 65   SLYDHILDMTTLLGAIPHRFGNTGDKISPDLYFAMARGTADQPAMEMTKWFNTNYHYIVP 124

Query: 439  ELGPDTKFSYSSHKAINEYKEAKALGVDTVPVLVGPVSYLLLSKAAKGVEKSFXXXXXXX 618
            E    T+F  +S +   E ++AKALG+    VL+GP++YL L K    V   F       
Sbjct: 125  EFDDTTQFRLASDRLFQEIEDAKALGITAKAVLIGPLTYLYLGKE---VTPGFQRLDLLP 181

Query: 619  XXXXVYKEVIAELKAAGASWIQFDEPTLVKDPESHQLAAFSAAYTELESTLSGLNVLVET 798
                VY+E++ ++ + G  W+Q DEP L  D E     +F+ AY  L        +L+ T
Sbjct: 182  RLLPVYREILQKIASLGVEWVQIDEPILSLDLEQPWRDSFAEAYHTLHD--GSCRLLLTT 239

Query: 799  YFADVPAESYKTLTSLSSVTAYGFDLERGTKTLELVKSGFPAGKYLFAGVVDGRYIWADD 978
            YF  V  + + TL     V     D+    + LE   +   +GK L  G +DGR IW  D
Sbjct: 240  YFGTV--DHHLTLLKNLPVDGLHIDVSSAPEQLESFLTEDFSGKTLSLGCIDGRNIWRAD 297

Query: 979  LAASLATL-QSLEAIVGKDKLVVSTSCSLMHTAVDLVNETKLDDEIKSWLAFAAQKVVEV 1155
            L+  L TL Q+     G+  L ++ SCSL+H  VDL  ETKL+ EIK+WLAF+AQK+ E+
Sbjct: 298  LSQKLETLSQAASRFAGE--LWIAPSCSLLHCPVDLALETKLEPEIKNWLAFSAQKLEEM 355

Query: 1156 NALAKALAGQKD--EXXXXXXXXXXXXXXXXXXVTNEEVQKAATALKGSDHRRATTVSAR 1329
              L + L   ++  E                  + N  V +    L   D +R    + R
Sbjct: 356  TTLGRGLNQGRESVEAILTASDEARRSRTESSRIHNPIVHQRVDNLTERDSQRNHPFATR 415

Query: 1330 LDAQQKKLNLPVLPTTTIGSFPQTVELRRVRREYKAKKISEEEYTNAIKEEISKVVKIQE 1509
               QQ++ NLP+LPTTTIGSFPQT  +R+ R  ++  ++S  EY +A++ EI ++++ QE
Sbjct: 416  KHLQQQRFNLPLLPTTTIGSFPQTATIRQARAAFRKNELSHLEYLSAMRAEIREMIRKQE 475

Query: 1510 ELDIDVLVHGEPERNDMVEYFGEQLSGFTFTANGWVQSYGSRCVKPPIIYGDVSRPNPMT 1689
            E+ +DVLVHGEPERNDMVEYFGEQL G+ FT NGWVQSYGSRCVKPPI+YGDV RP  MT
Sbjct: 476  EIGLDVLVHGEPERNDMVEYFGEQLWGYAFTENGWVQSYGSRCVKPPILYGDVYRPEAMT 535

Query: 1690 VFWSKMAQSMTARPMKGMLTGPVTILNWSFVRNDQPRFETCYQIALAIKKEVEDLEAGGI 1869
            V W K AQS T +P+KGMLTGPVT+L WSFVR+DQPR  T  Q+ALAI+ EV DLE  GI
Sbjct: 536  VEWIKYAQSQTGKPVKGMLTGPVTMLMWSFVRDDQPRSTTALQLALAIRDEVADLENAGI 595

Query: 1870 QVIQIDEAALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDTTQIHTHMCYSNFNDIIQS 2049
             +IQIDE A REGLPLRK +   YLDWAV +FR+ + GV+D TQIHTHMCYS F+DI+ +
Sbjct: 596  GMIQIDEPAFREGLPLRKQDWKSYLDWAVKAFRVASSGVKDETQIHTHMCYSEFHDILPA 655

Query: 2050 IINMDADVITIENSRSDEKLLSVFREGVVYGAGIGPGVYDIHSPRIPSKEEIADRVNKML 2229
            I  +DADVITIE SRS  +LL  F +   Y   IGPGVYDIHSPR+P   E+ + + K  
Sbjct: 656  IAELDADVITIETSRSRMELLDAFVK-FSYPNEIGPGVYDIHSPRVPDASEMFELLKKAS 714

Query: 2230 AVLDTNILWVNPDCGLKTRKYAEVKPALTNMVEAAKQIRAEL 2355
              +D  +LWVNPDCGLKTR + E + AL  MV+ AK +R+ L
Sbjct: 715  RYIDPTLLWVNPDCGLKTRNWPETQTALQKMVDCAKTLRSAL 756

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>P65340:METE_MYCTU 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase|
            - Mycobacterium tuberculosis
          Length = 759

 Score =  678 bits (1749), Expect = 0.0
 Identities = 369/759 (48%), Positives = 475/759 (62%), Gaps = 4/759 (0%)
 Frame = +1

Query: 85   IVGYPRMGPKRELKFALESFWDGKSSAEDLEKVATDLRASIWKQMAGAGIKYIPSNTFAY 264
            I G PR+GP+RELK A E +W G++S  +LE VA  LR   W  +A AG+  +P NTF+Y
Sbjct: 14   ITGSPRIGPRRELKRATEGYWAGRTSRSELEAVAATLRRDTWSALAAAGLDSVPVNTFSY 73

Query: 265  YDQVLDTTAMLGAVPDRYSWTGGEINLSTYFSMARGNATVPAMEMTKWFDTNYHFIVPEL 444
            YDQ+LDT  +LGA+P R S       L  YF+ ARG   +  +EMTKWFDTNYH++VPE+
Sbjct: 74   YDQMLDTAVLLGALPPRVSPVSD--GLDRYFAAARGTDQIAPLEMTKWFDTNYHYLVPEI 131

Query: 445  GPDTKFSYSSHKAINEYKEAKALGVDTVPVLVGPVSYLLLSKAAKGVEKSFXXXXXXXXX 624
            GP T F+    K + E KEA   G+   PV++GP+++LLLSKA  G              
Sbjct: 132  GPSTTFTLHPGKVLAELKEALGQGIPARPVIIGPITFLLLSKAVDGAGAPIERLEELVP- 190

Query: 625  XXVYKEVIAELKAAGASWIQFDEPTLVKDPESHQLAAFSAAYTELESTLSGLNVLVETYF 804
              VY E+++ L   GA W+QFDEP LV D      A   A YT L S  +   + V TYF
Sbjct: 191  --VYSELLSLLADGGAQWVQFDEPALVTDLSPDAPALAEAVYTALCSVSNRPAIYVATYF 248

Query: 805  ADVPAESYKTLTSLSSVTAYGFDLERGTKTLELVKSGFP--AGKYLFAGVVDGRYIWADD 978
             D P  +   L   + V A G DL  G  T     +G P  AGK L AGVVDGR +W  D
Sbjct: 249  GD-PGAALPALAR-TPVEAIGVDLVAGADTSV---AGVPELAGKTLVAGVVDGRNVWRTD 303

Query: 979  LAASLATLQSLEAIVGKDKLVVSTSCSLMHTAVDLVNETKLDDEIKSWLAFAAQKVVEVN 1158
            L A+L TL +L  +     + VSTSCS +H    L  ET LDD ++SWLAF A+KV EV 
Sbjct: 304  LEAALGTLATL--LGSAATVAVSTSCSTLHVPYSLEPETDLDDALRSWLAFGAEKVREVV 361

Query: 1159 ALAKALAGQKDEXXXXXXXXXXXXXXXXXX--VTNEEVQKAATALKGSDHRRATTVSARL 1332
             LA+AL    D                     + N +++    A+  S   R      R 
Sbjct: 362  VLARALRDGHDAVADEIASSRAAIASRKRDPRLHNGQIRARIEAIVASGAHRGNAAQRRA 421

Query: 1333 DAQQKKLNLPVLPTTTIGSFPQTVELRRVRREYKAKKISEEEYTNAIKEEISKVVKIQEE 1512
             +Q  +L+LP LPTTTIGS+PQT  +R  R   +A +I E EY   +++EI++V+ +QE 
Sbjct: 422  -SQDARLHLPPLPTTTIGSYPQTSAIRVARAALRAGEIDEAEYVRRMRQEITEVIALQER 480

Query: 1513 LDIDVLVHGEPERNDMVEYFGEQLSGFTFTANGWVQSYGSRCVKPPIIYGDVSRPNPMTV 1692
            L +DVLVHGEPERNDMV+YF EQL+GF  T NGWVQSYGSRCV+PPI+YGDVSRP  MTV
Sbjct: 481  LGLDVLVHGEPERNDMVQYFAEQLAGFFATQNGWVQSYGSRCVRPPILYGDVSRPRAMTV 540

Query: 1693 FWSKMAQSMTARPMKGMLTGPVTILNWSFVRNDQPRFETCYQIALAIKKEVEDLEAGGIQ 1872
             W   AQS+T +P+KGMLTGPVTIL WSFVR+DQP  +T  Q+ALAI+ E  DL++ GI 
Sbjct: 541  EWITYAQSLTDKPVKGMLTGPVTILAWSFVRDDQPLADTANQVALAIRDETVDLQSAGIA 600

Query: 1873 VIQIDEAALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDTTQIHTHMCYSNFNDIIQSI 2052
            VIQ+DE ALRE LPLR+++ A YL WAV +FR+   GV D TQIHTH+CYS F ++I +I
Sbjct: 601  VIQVDEPALRELLPLRRADQAEYLRWAVGAFRLATSGVSDATQIHTHLCYSEFGEVIGAI 660

Query: 2053 INMDADVITIENSRSDEKLLSVFREGVVYGAGIGPGVYDIHSPRIPSKEEIADRVNKMLA 2232
             ++DADV +IE +RS  ++L      + +  G+GPGVYDIHSPR+PS EE+AD +   L 
Sbjct: 661  ADLDADVTSIEAARSHMEVLDDL-NAIGFANGVGPGVYDIHSPRVPSAEEMADSLRAALR 719

Query: 2233 VLDTNILWVNPDCGLKTRKYAEVKPALTNMVEAAKQIRA 2349
             +    LWVNPDCGLKTR   EV  +L NMV AA+++RA
Sbjct: 720  AVPAERLWVNPDCGLKTRNVDEVTASLHNMVAAAREVRA 758

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>P65341:METE_MYCBO 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase|
            - Mycobacterium bovis
          Length = 759

 Score =  678 bits (1749), Expect = 0.0
 Identities = 369/759 (48%), Positives = 475/759 (62%), Gaps = 4/759 (0%)
 Frame = +1

Query: 85   IVGYPRMGPKRELKFALESFWDGKSSAEDLEKVATDLRASIWKQMAGAGIKYIPSNTFAY 264
            I G PR+GP+RELK A E +W G++S  +LE VA  LR   W  +A AG+  +P NTF+Y
Sbjct: 14   ITGSPRIGPRRELKRATEGYWAGRTSRSELEAVAATLRRDTWSALAAAGLDSVPVNTFSY 73

Query: 265  YDQVLDTTAMLGAVPDRYSWTGGEINLSTYFSMARGNATVPAMEMTKWFDTNYHFIVPEL 444
            YDQ+LDT  +LGA+P R S       L  YF+ ARG   +  +EMTKWFDTNYH++VPE+
Sbjct: 74   YDQMLDTAVLLGALPPRVSPVSD--GLDRYFAAARGTDQIAPLEMTKWFDTNYHYLVPEI 131

Query: 445  GPDTKFSYSSHKAINEYKEAKALGVDTVPVLVGPVSYLLLSKAAKGVEKSFXXXXXXXXX 624
            GP T F+    K + E KEA   G+   PV++GP+++LLLSKA  G              
Sbjct: 132  GPSTTFTLHPGKVLAELKEALGQGIPARPVIIGPITFLLLSKAVDGAGAPIERLEELVP- 190

Query: 625  XXVYKEVIAELKAAGASWIQFDEPTLVKDPESHQLAAFSAAYTELESTLSGLNVLVETYF 804
              VY E+++ L   GA W+QFDEP LV D      A   A YT L S  +   + V TYF
Sbjct: 191  --VYSELLSLLADGGAQWVQFDEPALVTDLSPDAPALAEAVYTALCSVSNRPAIYVATYF 248

Query: 805  ADVPAESYKTLTSLSSVTAYGFDLERGTKTLELVKSGFP--AGKYLFAGVVDGRYIWADD 978
             D P  +   L   + V A G DL  G  T     +G P  AGK L AGVVDGR +W  D
Sbjct: 249  GD-PGAALPALAR-TPVEAIGVDLVAGADTSV---AGVPELAGKTLVAGVVDGRNVWRTD 303

Query: 979  LAASLATLQSLEAIVGKDKLVVSTSCSLMHTAVDLVNETKLDDEIKSWLAFAAQKVVEVN 1158
            L A+L TL +L  +     + VSTSCS +H    L  ET LDD ++SWLAF A+KV EV 
Sbjct: 304  LEAALGTLATL--LGSAATVAVSTSCSTLHVPYSLEPETDLDDALRSWLAFGAEKVREVV 361

Query: 1159 ALAKALAGQKDEXXXXXXXXXXXXXXXXXX--VTNEEVQKAATALKGSDHRRATTVSARL 1332
             LA+AL    D                     + N +++    A+  S   R      R 
Sbjct: 362  VLARALRDGHDAVADEIASSRAAIASRKRDPRLHNGQIRARIEAIVASGAHRGNAAQRRA 421

Query: 1333 DAQQKKLNLPVLPTTTIGSFPQTVELRRVRREYKAKKISEEEYTNAIKEEISKVVKIQEE 1512
             +Q  +L+LP LPTTTIGS+PQT  +R  R   +A +I E EY   +++EI++V+ +QE 
Sbjct: 422  -SQDARLHLPPLPTTTIGSYPQTSAIRVARAALRAGEIDEAEYVRRMRQEITEVIALQER 480

Query: 1513 LDIDVLVHGEPERNDMVEYFGEQLSGFTFTANGWVQSYGSRCVKPPIIYGDVSRPNPMTV 1692
            L +DVLVHGEPERNDMV+YF EQL+GF  T NGWVQSYGSRCV+PPI+YGDVSRP  MTV
Sbjct: 481  LGLDVLVHGEPERNDMVQYFAEQLAGFFATQNGWVQSYGSRCVRPPILYGDVSRPRAMTV 540

Query: 1693 FWSKMAQSMTARPMKGMLTGPVTILNWSFVRNDQPRFETCYQIALAIKKEVEDLEAGGIQ 1872
             W   AQS+T +P+KGMLTGPVTIL WSFVR+DQP  +T  Q+ALAI+ E  DL++ GI 
Sbjct: 541  EWITYAQSLTDKPVKGMLTGPVTILAWSFVRDDQPLADTANQVALAIRDETVDLQSAGIA 600

Query: 1873 VIQIDEAALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDTTQIHTHMCYSNFNDIIQSI 2052
            VIQ+DE ALRE LPLR+++ A YL WAV +FR+   GV D TQIHTH+CYS F ++I +I
Sbjct: 601  VIQVDEPALRELLPLRRADQAEYLRWAVGAFRLATSGVSDATQIHTHLCYSEFGEVIGAI 660

Query: 2053 INMDADVITIENSRSDEKLLSVFREGVVYGAGIGPGVYDIHSPRIPSKEEIADRVNKMLA 2232
             ++DADV +IE +RS  ++L      + +  G+GPGVYDIHSPR+PS EE+AD +   L 
Sbjct: 661  ADLDADVTSIEAARSHMEVLDDL-NAIGFANGVGPGVYDIHSPRVPSAEEMADSLRAALR 719

Query: 2233 VLDTNILWVNPDCGLKTRKYAEVKPALTNMVEAAKQIRA 2349
             +    LWVNPDCGLKTR   EV  +L NMV AA+++RA
Sbjct: 720  AVPAERLWVNPDCGLKTRNVDEVTASLHNMVAAAREVRA 758

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>Q73WJ9:METE_MYCPA 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase|
            - Mycobacterium paratuberculosis
          Length = 756

 Score =  669 bits (1726), Expect = 0.0
 Identities = 363/764 (47%), Positives = 480/764 (62%), Gaps = 2/764 (0%)
 Frame = +1

Query: 64   PGKMASHIVGYPRMGPKRELKFALESFWDGKSSAEDLEKVATDLRASIWKQMAGAGIKYI 243
            P    + +VG PR+GPKRELK A E +W G++   +LEKVA  LR   W  +A AG+  +
Sbjct: 3    PQAFTATVVGSPRIGPKRELKRATEGYWAGRTGRAELEKVAATLRRDTWAGLAAAGLDSV 62

Query: 244  PSNTFAYYDQVLDTTAMLGAVPDRYSWTGGEINLSTYFSMARGNATVPAMEMTKWFDTNY 423
            P NTF+YYDQ+LDT  ML A+P+R      +  L  YF+ ARGN+ V  +EMTKWFDTNY
Sbjct: 63   PVNTFSYYDQMLDTAVMLDALPERARQVSDD--LDRYFAAARGNSDVAPLEMTKWFDTNY 120

Query: 424  HFIVPELGPDTKFSYSSHKAINEYKEAKALGVDTVPVLVGPVSYLLLSKAAKGVEKSFXX 603
            H+IVPE+ P TKF+ +  K ++E KEA A G+   PV++GP+++LLLSK   GV+ +   
Sbjct: 121  HYIVPEIAPTTKFALNPDKVLSELKEALAQGIPARPVVIGPITFLLLSK---GVDGAGAP 177

Query: 604  XXXXXXXXXVYKEVIAELKAAGASWIQFDEPTLVKDPESHQLAAFSAAYTELESTLSGLN 783
                     +Y E+++ L   GA W+Q DEP LV D  +   A   A Y +L S  +   
Sbjct: 178  IERLEELVPIYAELLSLLADNGAQWVQLDEPALVTDMCADAPALAEAVYNKLGSASNRPA 237

Query: 784  VLVETYFADVPAESYKTLTSLSSVTAYGFDLERGTKTLELVKSGFPAGKYLFAGVVDGRY 963
            + V TYF D P  S   L   + V A G DL  G  T         AGK + AGVVDGR 
Sbjct: 238  IYVATYFGD-PGASLAGLAR-TPVEAIGVDLVYGPDTAVAAVPEL-AGKTVVAGVVDGRN 294

Query: 964  IWADDLAASLATLQSLEAIVGKDKLVVSTSCSLMHTAVDLVNETKLDDEIKSWLAFAAQK 1143
            +W  DLAA+L  L +L  +    ++ VSTSCS +H    L  ET LDD ++SWLAF  +K
Sbjct: 295  VWRTDLAAALDKLTTL--LGSAARVAVSTSCSTLHVPYSLEPETDLDDALRSWLAFGREK 352

Query: 1144 VVEVNALAKALAGQKDEXXXXXXXXXXXXXXXXXX--VTNEEVQKAATALKGSDHRRATT 1317
            V EV  LA+AL   ++                     + N+ V+    ++  S   R   
Sbjct: 353  VAEVVTLARALRDGREAVADEIAASNAAVASRKSDPRLHNDRVRARIDSIVASGSHRGDP 412

Query: 1318 VSARLDAQQKKLNLPVLPTTTIGSFPQTVELRRVRREYKAKKISEEEYTNAIKEEISKVV 1497
               R  +Q  +L+LP LPTTTIGS+PQT  +R+ R   ++ +I + EY   +K+EI+ V+
Sbjct: 413  AQRRA-SQDARLHLPPLPTTTIGSYPQTSAIRKARAALRSGEIDQAEYERRMKKEIADVI 471

Query: 1498 KIQEELDIDVLVHGEPERNDMVEYFGEQLSGFTFTANGWVQSYGSRCVKPPIIYGDVSRP 1677
             +QE+L +DVLVHGEPERNDMV+YF EQL GF  T NGWVQSYGSRCV+PPI+YGDV R 
Sbjct: 472  TLQEQLGLDVLVHGEPERNDMVQYFAEQLEGFFATQNGWVQSYGSRCVRPPILYGDVVRT 531

Query: 1678 NPMTVFWSKMAQSMTARPMKGMLTGPVTILNWSFVRNDQPRFETCYQIALAIKKEVEDLE 1857
            +PMTV W   AQS+T +P+KGMLTGPVTIL WSFVR+DQP  +T  Q+ALAI+ E  DL+
Sbjct: 532  HPMTVEWISYAQSLTDKPVKGMLTGPVTILAWSFVRDDQPLADTANQVALAIRDETVDLQ 591

Query: 1858 AGGIQVIQIDEAALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDTTQIHTHMCYSNFND 2037
            A GI VIQ+DE ALRE LPLR+++   YL WAV +FR+   GV D+TQIHTH+CYS F +
Sbjct: 592  AAGIAVIQVDEPALRELLPLRRADQDEYLRWAVGAFRLATSGVADSTQIHTHLCYSEFGE 651

Query: 2038 IIQSIINMDADVITIENSRSDEKLLSVFREGVVYGAGIGPGVYDIHSPRIPSKEEIADRV 2217
            +I +I ++DADV ++E +RS  ++L      V +   +GPGVYDIHSPR+PS  EIA+ +
Sbjct: 652  VIGAIADLDADVTSLEAARSHMEVLDDL-NAVGFSNSVGPGVYDIHSPRVPSTAEIAESL 710

Query: 2218 NKMLAVLDTNILWVNPDCGLKTRKYAEVKPALTNMVEAAKQIRA 2349
               L  +    LWVNPDCGLKTR   EV  +L NMV AA ++RA
Sbjct: 711  RAALRAVPAERLWVNPDCGLKTRNPDEVSASLKNMVAAAHEVRA 754

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>Q82LG4:METE_STRAW 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase|
            - Streptomyces avermitilis
          Length = 772

 Score =  669 bits (1725), Expect = 0.0
 Identities = 364/762 (47%), Positives = 468/762 (61%), Gaps = 4/762 (0%)
 Frame = +1

Query: 85   IVGYPRMGPKRELKFALESFWDGKSSAEDLEKVATDLRASIWKQMAGAGIKYIPSNTFAY 264
            + GYPR G  RELK A+E +W G+  A+ L   AT LR   W+Q+A AGI  +P+  F+Y
Sbjct: 14   VYGYPRQGRGRELKKAIEGYWKGRLDADALRTTATGLRRDTWQQLAEAGIHEVPTGDFSY 73

Query: 265  YDQVLDTTAMLGAVPDRYSWTGGEINLSTYFSMARGNATVPAMEMTKWFDTNYHFIVPEL 444
            YD VLDT+ M+GA+P R+        L  YF+MARG   V  +EMTKWFDTNYH++VPEL
Sbjct: 74   YDHVLDTSVMVGAIPARHRAAVEADALDGYFAMARGTQDVAPLEMTKWFDTNYHYLVPEL 133

Query: 445  GPDTKFSYSSHKAINEYKEAKALGVDTVPVLVGPVSYLLLSKAAKGVEKSFXXXXXXXXX 624
            GPDT FS  S K + E  EA ALG+   PVLVGPV+YLLL+K A GV   F         
Sbjct: 134  GPDTVFSTDSAKQVAELGEALALGLTARPVLVGPVTYLLLAKPAPGVAADFDPLTLLDRL 193

Query: 625  XXVYKEVIAELKAAGASWIQFDEPTLVKDPESHQLAAFSAAYTELESTLSGLNVLVETYF 804
              VY EV+A+L+AAGA W+Q DEP LV+D    +L A   AY  L        +LV +YF
Sbjct: 194  LPVYAEVLADLRAAGAEWVQLDEPALVQDRTPAELNAAERAYRVLGGLTDRPKLLVASYF 253

Query: 805  ADVPAESYKTLTSLSSVTAYGFDLERGTKTL--ELVKSGFPAGKYLFAGVVDGRYIWADD 978
             D   ++   L   + V     D   G       L   G   GK L AGVVDGR IW +D
Sbjct: 254  -DRLGDALPVLAE-APVEGLALDFAEGAAANLDALAAVGGLPGKRLVAGVVDGRNIWVND 311

Query: 979  LAASLATLQSLEAIVGKDKLVVSTSCSLMHTAVDLVNETKLDDEIKSWLAFAAQKVVEVN 1158
            L  SLA L +L  +   D++ V+ SCSL+H  +D   E  +  ++  WLAFA QK  E+ 
Sbjct: 312  LEKSLALLGTLLGLA--DRVDVAASCSLLHVPLDAAAERDIAPQVLRWLAFARQKTAEIV 369

Query: 1159 ALAKALAGQKDEXXXXXXXXXXXXXXXXXXVTNEE--VQKAATALKGSDHRRATTVSARL 1332
             LAK L    D                       +  V+    A   +D RR+     R 
Sbjct: 370  TLAKGLGHGTDAIAAQLAANRADLVSRADSALTRDPAVRSRTAATTDADARRSGPYPERA 429

Query: 1333 DAQQKKLNLPVLPTTTIGSFPQTVELRRVRREYKAKKISEEEYTNAIKEEISKVVKIQEE 1512
             AQ+ +L LP+LPTTTIGSFPQT ELR  R + +A +I    Y   I+ EI +V+  QE+
Sbjct: 430  AAQRARLGLPLLPTTTIGSFPQTAELRTARADLRAGRIDSAGYEERIRAEIGEVISFQEK 489

Query: 1513 LDIDVLVHGEPERNDMVEYFGEQLSGFTFTANGWVQSYGSRCVKPPIIYGDVSRPNPMTV 1692
              +DVLVHGE ERNDMV+YF E+L+G+  T +GWVQSYG+R V+PP++ GD+SRP PMTV
Sbjct: 490  AGLDVLVHGEAERNDMVQYFAERLTGYLTTQHGWVQSYGTRYVRPPVLAGDISRPEPMTV 549

Query: 1693 FWSKMAQSMTARPMKGMLTGPVTILNWSFVRNDQPRFETCYQIALAIKKEVEDLEAGGIQ 1872
             W+  AQS+T RP+KGMLTGPVT+L WSFVR+DQP  ET  Q+ALA++ EV DLEA G  
Sbjct: 550  PWTTYAQSLTDRPVKGMLTGPVTMLAWSFVRDDQPLGETARQVALALRDEVGDLEAAGTS 609

Query: 1873 VIQIDEAALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDTTQIHTHMCYSNFNDIIQSI 2052
            VIQ+DE ALRE LPLR ++   YL WA  +FR+T  GV+  TQIHTHMCY+ F DI+Q+I
Sbjct: 610  VIQVDEPALRETLPLRAADRPAYLAWATEAFRLTTGGVRPDTQIHTHMCYAEFGDIVQAI 669

Query: 2053 INMDADVITIENSRSDEKLLSVFREGVVYGAGIGPGVYDIHSPRIPSKEEIADRVNKMLA 2232
             ++DADVI++E +RS  ++     E   Y    GPGVYDIHSPR+P  +E A  + K L 
Sbjct: 670  DDLDADVISLEAARSHMQVARELAEH-AYPREAGPGVYDIHSPRVPGVDETAALLRKGLE 728

Query: 2233 VLDTNILWVNPDCGLKTRKYAEVKPALTNMVEAAKQIRAELA 2358
             +    LWVNPDCGLKTR + E + +L N+V AA+ +RAE A
Sbjct: 729  AIPAERLWVNPDCGLKTRGWPETRASLENLVAAARTVRAEHA 770

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>Q9JUT6:METE_NEIMA 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase|
            - Neisseria meningitidis serogroup A
          Length = 758

 Score =  669 bits (1725), Expect = 0.0
 Identities = 369/765 (48%), Positives = 474/765 (61%), Gaps = 5/765 (0%)
 Frame = +1

Query: 82   HIVGYPRMGPKRELKFALESFWDGKSSAEDLEKVATDLRASIWKQMAGAGIKYIPSNTFA 261
            H  G+PR+G  RELKFA E +W  + S ++L  VA DLR   WK  A A   Y+    F 
Sbjct: 5    HFSGFPRVGAFRELKFAQEKYWRKEISEQELLAVAKDLREKNWKHQAAANADYVAVGDFT 64

Query: 262  YYDQVLDTTAMLGAVPDRYSWTGGEINLSTYFSMARGNATVPAMEMTKWFDTNYHFIVPE 441
            +YD +LD     GA+P R+ +    ++L  +F +ARGN    A+EMTKWFDTNYH++VPE
Sbjct: 65   FYDHILDLQVATGAIPARFGFDSQNLSLEQFFQLARGNKDQFAIEMTKWFDTNYHYLVPE 124

Query: 442  LGPDTKFSYSSHKAINEYKEAKALGVDTVPVLVGPVSYLLLSKAAKGVEKSFXXXXXXXX 621
               DT+F  ++   + + +EA+ALG+   P +VGP+++L + K    VE  F        
Sbjct: 125  FHADTEFKANAKHYVQQLQEAQALGLKAKPTVVGPLTFLWVGKEKGAVE--FDRLSLLPK 182

Query: 622  XXXVYKEVIAELKAAGASWIQFDEPTLVKDPESHQLAAFSAAYTELESTLSGLNVLVETY 801
               VY E++  L  AGA WIQ DEP L  D     + A+   Y  L    +   +L+ TY
Sbjct: 183  LLPVYVEILTALVEAGAEWIQIDEPALTVDLPKEWVEAYKDVYATLSKVSA--KILLSTY 240

Query: 802  FADVPAESYKTLTSLSSVTAYGFDLERGTKTLELVKSGFPAGKYLFAGVVDGRYIWADDL 981
            F  V AE    L SL  V     DL R  + L+         K L AGV+DGR IW  +L
Sbjct: 241  FGSV-AEHAALLKSLP-VDGLHIDLVRAPEQLDAFAD---YDKVLSAGVIDGRNIWRANL 295

Query: 982  AASLATLQSLEAIVGKDKLVVSTSCSLMHTAVDLVNETKLD---DEIKSWLAFAAQKVVE 1152
               L T++ L+A +G D+L +S+SCSL+HT  DL  E KL     ++ SWLAF  QK  E
Sbjct: 296  NKVLETVELLQAKLG-DRLWISSSCSLLHTPFDLSVEEKLKANKPDLYSWLAFTLQKTQE 354

Query: 1153 VNALAKALAGQKDEXXXXXXXXXXXXXXXXXX--VTNEEVQKAATALKGSDHRRATTVSA 1326
            +  L  AL   +D                     +   +V K    L  +  +R +  + 
Sbjct: 355  LRVLKAALNEGRDSVAEELAASQAAADSRANSSEIHRADVAKRLADLPANADQRKSPFAD 414

Query: 1327 RLDAQQKKLNLPVLPTTTIGSFPQTVELRRVRREYKAKKISEEEYTNAIKEEISKVVKIQ 1506
            R+ AQQ  LNLP+LPTT IGSFPQT E+R+ R  +K  ++S  +Y  A+K+EI+ VV+ Q
Sbjct: 415  RIKAQQAWLNLPLLPTTNIGSFPQTTEIRQARAAFKKGELSAADYEAAMKKEIALVVEEQ 474

Query: 1507 EELDIDVLVHGEPERNDMVEYFGEQLSGFTFTANGWVQSYGSRCVKPPIIYGDVSRPNPM 1686
            E+LD+DVLVHGE ERNDMVEYFGE LSGF FT  GWVQSYGSRCVKPPII+GDVSRP  M
Sbjct: 475  EKLDLDVLVHGEAERNDMVEYFGELLSGFAFTQYGWVQSYGSRCVKPPIIFGDVSRPEAM 534

Query: 1687 TVFWSKMAQSMTARPMKGMLTGPVTILNWSFVRNDQPRFETCYQIALAIKKEVEDLEAGG 1866
            TV WS  AQS+T RPMKGMLTGPVTIL WSFVRND PR   C QIALA+  EV DLE  G
Sbjct: 535  TVAWSTYAQSLTKRPMKGMLTGPVTILQWSFVRNDIPRSTVCKQIALALNDEVLDLEKAG 594

Query: 1867 IQVIQIDEAALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDTTQIHTHMCYSNFNDIIQ 2046
            I+VIQIDE A+REGLPL++++   YL+WA  SFR+++ G +D+TQIHTHMCYS FNDI+ 
Sbjct: 595  IKVIQIDEPAIREGLPLKRADWDAYLNWAGESFRLSSTGCEDSTQIHTHMCYSEFNDILP 654

Query: 2047 SIINMDADVITIENSRSDEKLLSVFREGVVYGAGIGPGVYDIHSPRIPSKEEIADRVNKM 2226
            +I  MDADVITIE SRSD +LL+ F E   Y   IGPGVYDIHSPR+P++ E+   + K 
Sbjct: 655  AIAAMDADVITIETSRSDMELLTAFGE-FKYPNDIGPGVYDIHSPRVPTEAEVEHLLRKA 713

Query: 2227 LAVLDTNILWVNPDCGLKTRKYAEVKPALTNMVEAAKQIRAELAK 2361
            + V+    LWVNPDCGLKTR + E    L  M+    ++RAELAK
Sbjct: 714  IEVVPVERLWVNPDCGLKTRGWKETLEQLQVMMNVTHKLRAELAK 758

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>P45331:METE_HAEIN 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase|
            - Haemophilus influenzae
          Length = 756

 Score =  667 bits (1720), Expect = 0.0
 Identities = 371/769 (48%), Positives = 485/769 (63%), Gaps = 9/769 (1%)
 Frame = +1

Query: 79   SHIVGYPRMGPKRELKFALESFWDGKSSAEDLEKVATDLRASIWKQMAGAGIKYIPSNTF 258
            SHI+G+PR+G KRELKFA E +W  + + +DL  +A  LR   WK  A A   ++    F
Sbjct: 4    SHILGFPRVGAKRELKFAQERYWRKELAEQDLLDLAKALREKNWKHQAAANADFVAVGDF 63

Query: 259  AYYDQVLDTTAMLGAVPDRYSWTGGEINLSTYFSMARGNATVPAMEMTKWFDTNYHFIVP 438
             +YD +LD     GA+P R+ +    + L  YF +ARGN    A+EMTKWFDTNYH++VP
Sbjct: 64   TFYDHILDLQVATGAIPARFGFDSQNLTLDQYFQLARGNKDQFAIEMTKWFDTNYHYLVP 123

Query: 439  ELGPDTKFSYSSHKAINEYKEAKALGVDTVPVLVGPVSYLLLSKAAKGVEKSFXXXXXXX 618
            E    T F  +    +N+ +EAKALG++  PV+VGP+++L L K  KG  ++F       
Sbjct: 124  EFQKSTAFKANPAHYVNQIREAKALGLNFKPVIVGPLTFLWLGKE-KG--EAFNRFDLLN 180

Query: 619  XXXXVYKEVIAELKAAGASWIQFDEPTLVKDPESHQLAAFSAAYTELESTLSGLNVLVET 798
                VY E++  L A GA WIQ DEP L  D  +  + A+ + YTEL    + L  L+ T
Sbjct: 181  QLVPVYVEILNALVAEGAEWIQIDEPALALDLPAEWVEAYKSVYTELSKVNAKL--LLAT 238

Query: 799  YFADVPAESYKTLTSLSSVTAYGFDLERGTKTLELVKSGFPAGKYLFAGVVDGRYIWADD 978
            YF  V AE  + L +L  V     DL R  + L   +      K L AGV++GR IW  +
Sbjct: 239  YFGSV-AEHAELLKALP-VAGLHLDLVRAPEQLAAFED---YSKVLSAGVIEGRNIWRAN 293

Query: 979  LAASLATLQSLEAIVGKDKLVVSTSCSLMHTAVDLVNETKLDDE---IKSWLAFAAQKVV 1149
            L   L  L+ L+A +G ++L ++ SCSL+HT  DL  E +L ++   + SWL+F  QKV 
Sbjct: 294  LNKVLDVLEPLKAKLG-ERLWIAPSCSLLHTPFDLEVEVQLKEKNTALYSWLSFTLQKVE 352

Query: 1150 EVNALAKALAGQKDEXXXXXXXXXXXXXXXXXXVTNEEV------QKAATALKGSDHRRA 1311
            E+N L +AL   +                     T++E+      ++ A   KG+D R++
Sbjct: 353  ELNVLKQALNNGRASVQAALDASQVAADAR---ATSKEIHRPEVAERLANLPKGADQRKS 409

Query: 1312 TTVSARLDAQQKKLNLPVLPTTTIGSFPQTVELRRVRREYKAKKISEEEYTNAIKEEISK 1491
               + R+  Q   LNLP+LPTT IGSFPQT E+R  R  +K  ++S  +Y  A+K+EI  
Sbjct: 410  P-FAERIVKQNAWLNLPLLPTTNIGSFPQTTEIRHARASFKKGELSLADYEAAMKKEIEY 468

Query: 1492 VVKIQEELDIDVLVHGEPERNDMVEYFGEQLSGFTFTANGWVQSYGSRCVKPPIIYGDVS 1671
            VV+ QEELD+DVLVHGE ERNDMVEYFGE L GF FT  GWVQSYGSRCVKPP+IYGDV+
Sbjct: 469  VVRRQEELDLDVLVHGEAERNDMVEYFGELLDGFAFTKFGWVQSYGSRCVKPPVIYGDVT 528

Query: 1672 RPNPMTVFWSKMAQSMTARPMKGMLTGPVTILNWSFVRNDQPRFETCYQIALAIKKEVED 1851
            RP PMTV WS+ AQS+T R MKGMLTGPVTIL WSFVRND PR   C QI +A+  EV D
Sbjct: 529  RPEPMTVRWSQYAQSLTNRVMKGMLTGPVTILQWSFVRNDIPRSTVCKQIGVALSDEVLD 588

Query: 1852 LEAGGIQVIQIDEAALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDTTQIHTHMCYSNF 2031
            LEA GI+VIQIDE A+REGLPL++++   YL WA  +FR+++ GVQD TQIHTHMCYS F
Sbjct: 589  LEAAGIKVIQIDEPAIREGLPLKRADWDAYLQWAGEAFRLSSMGVQDDTQIHTHMCYSEF 648

Query: 2032 NDIIQSIINMDADVITIENSRSDEKLLSVFREGVVYGAGIGPGVYDIHSPRIPSKEEIAD 2211
            NDI+ +I  +DADVITIE SRSD +LL+ F +   Y   IGPGVYDIHSPR+P+  E+  
Sbjct: 649  NDILPAIAALDADVITIETSRSDMELLTAFAD-FKYPNDIGPGVYDIHSPRVPTATEVEH 707

Query: 2212 RVNKMLAVLDTNILWVNPDCGLKTRKYAEVKPALTNMVEAAKQIRAELA 2358
             + K L V+    LWVNPDCGLKTR + E    L  MV+  K++RAELA
Sbjct: 708  LLRKALNVIPKERLWVNPDCGLKTRGWTETIDQLKVMVDVTKKLRAELA 756

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>Q9JZQ2:METE_NEIMB 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase|
            - Neisseria meningitidis serogroup B
          Length = 758

 Score =  666 bits (1719), Expect = 0.0
 Identities = 366/765 (47%), Positives = 474/765 (61%), Gaps = 5/765 (0%)
 Frame = +1

Query: 82   HIVGYPRMGPKRELKFALESFWDGKSSAEDLEKVATDLRASIWKQMAGAGIKYIPSNTFA 261
            H  G+PR+G  RELKFA E +W  + S ++L  VA DLR   WK    A   ++    F 
Sbjct: 5    HFSGFPRVGAFRELKFAQEKYWRKEISEQELLAVAKDLREKNWKHQVAANADFVAVGDFT 64

Query: 262  YYDQVLDTTAMLGAVPDRYSWTGGEINLSTYFSMARGNATVPAMEMTKWFDTNYHFIVPE 441
            +YD +LD     GA+P R+ +    ++L  +F +ARGN    A+EMTKWFDTNYH++VPE
Sbjct: 65   FYDHILDLQVATGAIPARFGFDSQNLSLEQFFQLARGNKDQFAIEMTKWFDTNYHYLVPE 124

Query: 442  LGPDTKFSYSSHKAINEYKEAKALGVDTVPVLVGPVSYLLLSKAAKGVEKSFXXXXXXXX 621
               DT+F  ++   + + +EA+ALG+   P +VGP+++L + K    VE  F        
Sbjct: 125  FHADTEFKANAKHYVQQLQEAQALGLKAKPTVVGPLTFLWVGKEKGAVE--FDRLSLLPK 182

Query: 622  XXXVYKEVIAELKAAGASWIQFDEPTLVKDPESHQLAAFSAAYTELESTLSGLNVLVETY 801
               VY E++  L  AGA WIQ DEP L  D     + A+   Y  L    +   +L+ TY
Sbjct: 183  LLPVYVEILTALVEAGAEWIQIDEPALAVDLPKEWVEAYKDVYATLSKVSA--KILLSTY 240

Query: 802  FADVPAESYKTLTSLSSVTAYGFDLERGTKTLELVKSGFPAGKYLFAGVVDGRYIWADDL 981
            F  V AE    L +L  V     DL R  + L+         K L AGV+DGR IW  +L
Sbjct: 241  FGSV-AEHAALLKALP-VDGLHIDLVRAPEQLDAFAD---YDKVLSAGVIDGRNIWRANL 295

Query: 982  AASLATLQSLEAIVGKDKLVVSTSCSLMHTAVDLVNETKLD---DEIKSWLAFAAQKVVE 1152
               L T++ L+A +G D+L +S+SCSL+HT  DL  E KL     ++ SWLAF  QK  E
Sbjct: 296  NKVLETVEPLQAKLG-DRLWISSSCSLLHTPFDLSVEEKLKANKPDLYSWLAFTLQKTQE 354

Query: 1153 VNALAKALAGQKDEXXXXXXXXXXXXXXXXXX--VTNEEVQKAATALKGSDHRRATTVSA 1326
            +  L  AL   +D                     +   +V K    L  +  +R +  + 
Sbjct: 355  LRVLKAALNEGRDSVAEELAASQAAADSRANSSEIHRADVAKRLADLPANADQRKSPFAD 414

Query: 1327 RLDAQQKKLNLPVLPTTTIGSFPQTVELRRVRREYKAKKISEEEYTNAIKEEISKVVKIQ 1506
            R+ AQQ  LNLP+LPTT IGSFPQT E+R+ R  +K  ++S  +Y  A+K+EI+ VV+ Q
Sbjct: 415  RIKAQQAWLNLPLLPTTNIGSFPQTTEIRQARSAFKKGELSAADYEAAMKKEIALVVEEQ 474

Query: 1507 EELDIDVLVHGEPERNDMVEYFGEQLSGFTFTANGWVQSYGSRCVKPPIIYGDVSRPNPM 1686
            E+LD+DVLVHGE ERNDMVEYFGE LSGF FT  GWVQSYGSRCVKPPII+GDVSRP  M
Sbjct: 475  EKLDLDVLVHGEAERNDMVEYFGELLSGFAFTQYGWVQSYGSRCVKPPIIFGDVSRPEAM 534

Query: 1687 TVFWSKMAQSMTARPMKGMLTGPVTILNWSFVRNDQPRFETCYQIALAIKKEVEDLEAGG 1866
            TV WS  AQS+T RPMKGMLTGPVTIL WSFVRND PR   C QIALA+  EV DLE  G
Sbjct: 535  TVAWSTYAQSLTKRPMKGMLTGPVTILQWSFVRNDIPRSTVCKQIALALNDEVLDLEKAG 594

Query: 1867 IQVIQIDEAALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDTTQIHTHMCYSNFNDIIQ 2046
            I+VIQIDE A+REGLPL++++   YL+WA  SFR+++ G +D+TQIHTHMCYS FNDI+ 
Sbjct: 595  IKVIQIDEPAIREGLPLKRADWDAYLNWAGESFRLSSAGCEDSTQIHTHMCYSEFNDILP 654

Query: 2047 SIINMDADVITIENSRSDEKLLSVFREGVVYGAGIGPGVYDIHSPRIPSKEEIADRVNKM 2226
            +I  MDADVITIE SRSD +LL+ F E   Y   IGPGVYDIHSPR+P++ E+   + K 
Sbjct: 655  AIAAMDADVITIETSRSDMELLTAFGE-FQYPNDIGPGVYDIHSPRVPTEAEVEHLLRKA 713

Query: 2227 LAVLDTNILWVNPDCGLKTRKYAEVKPALTNMVEAAKQIRAELAK 2361
            + V+    LWVNPDCGLKTR + E    L  M+   +++RAELAK
Sbjct: 714  IEVVPVERLWVNPDCGLKTRGWKETLEQLQVMMNVTRKLRAELAK 758

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>O05564:METE_MYCLE 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase|
            - Mycobacterium leprae
          Length = 760

 Score =  661 bits (1706), Expect = 0.0
 Identities = 357/757 (47%), Positives = 474/757 (62%), Gaps = 2/757 (0%)
 Frame = +1

Query: 85   IVGYPRMGPKRELKFALESFWDGKSSAEDLEKVATDLRASIWKQMAGAGIKYIPSNTFAY 264
            + G PR+GP+RELK A E +W  ++S  +LE VA+ LR  +W  +A AG+  +P NTF+Y
Sbjct: 14   VTGSPRIGPRRELKRATEGYWAKRTSRSELESVASTLRRDMWSDLAAAGLDSVPVNTFSY 73

Query: 265  YDQVLDTTAMLGAVPDRYSWTGGEINLSTYFSMARGNATVPAMEMTKWFDTNYHFIVPEL 444
            YDQ+LDT  MLGA+P R +    +  L  YF++ARGN  +  +EMTKWFDTNYH++VPE+
Sbjct: 74   YDQMLDTAFMLGALPARVAQVSDD--LDQYFALARGNNDIKPLEMTKWFDTNYHYLVPEI 131

Query: 445  GPDTKFSYSSHKAINEYKEAKALGVDTVPVLVGPVSYLLLSKAAKGVEKSFXXXXXXXXX 624
             P T FS +  K + E KEA    + + PV++GPV++LLLSK   G+             
Sbjct: 132  EPATTFSLNPGKILGELKEALEQRIPSRPVIIGPVTFLLLSK---GINGGGAPIQRLEEL 188

Query: 625  XXVYKEVIAELKAAGASWIQFDEPTLVKDPESHQLAAFSAAYTELESTLSGLNVLVETYF 804
              +Y  +++ L   GA W+QFDEP LV D      A   A YT L S      + V TYF
Sbjct: 189  VGIYCTLLSLLAENGARWVQFDEPALVTDLSPDAPALAEAVYTALGSVSKRPAIYVATYF 248

Query: 805  ADVPAESYKTLTSLSSVTAYGFDLERGTKTLELVKSGFPAGKYLFAGVVDGRYIWADDLA 984
             + P  S   L   + + A G D   G  T         AGK L AG+VDGR IW  DL 
Sbjct: 249  GN-PGASLAGLAR-TPIEAIGVDFVCGADTSVAAVPEL-AGKTLVAGIVDGRNIWRTDLE 305

Query: 985  ASLATLQSLEAIVGKDKLVVSTSCSLMHTAVDLVNETKLDDEIKSWLAFAAQKVVEVNAL 1164
            ++L+ L +L  +     + VSTSCS +H    L  ET LDD ++SWLAF A+KV EV  L
Sbjct: 306  SALSKLATL--LGSAATVAVSTSCSTLHVPYSLEPETDLDDNLRSWLAFGAEKVAEVVVL 363

Query: 1165 AKALAGQKDEXXXXXXXXXXXXXXXXXX--VTNEEVQKAATALKGSDHRRATTVSARLDA 1338
            A+AL   +D                     + N +V+    ++  S   R      R  +
Sbjct: 364  ARALRDGRDAVADEIAASNAAVASRRSDPRLHNGQVRARIDSIVASGTHRGDAAQRRT-S 422

Query: 1339 QQKKLNLPVLPTTTIGSFPQTVELRRVRREYKAKKISEEEYTNAIKEEISKVVKIQEELD 1518
            Q  +L+LP LPTTTIGS+PQT  +R+ R   +  +I E EY + +K+E++  +K+QE+L 
Sbjct: 423  QDARLHLPPLPTTTIGSYPQTSAIRKARAALQDAEIDEAEYISRMKKEVADAIKLQEQLG 482

Query: 1519 IDVLVHGEPERNDMVEYFGEQLSGFTFTANGWVQSYGSRCVKPPIIYGDVSRPNPMTVFW 1698
            +DVLVHGEPERNDMV+YF EQL GF  T NGWVQSYGSRCV+PPI+YGDVSRP+PMT+ W
Sbjct: 483  LDVLVHGEPERNDMVQYFAEQLGGFFATQNGWVQSYGSRCVRPPILYGDVSRPHPMTIEW 542

Query: 1699 SKMAQSMTARPMKGMLTGPVTILNWSFVRNDQPRFETCYQIALAIKKEVEDLEAGGIQVI 1878
               AQS+T +P+KGMLTGPVTIL WSFVR+DQP  +T  Q+ALAI+ E  DL++ GI +I
Sbjct: 543  ITYAQSLTDKPVKGMLTGPVTILAWSFVRDDQPLADTANQVALAIRDETVDLQSAGIAII 602

Query: 1879 QIDEAALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDTTQIHTHMCYSNFNDIIQSIIN 2058
            Q+DE ALRE LPLR+++   YL WAV +FR+   GV D+TQIHTH+CYS F ++I +I +
Sbjct: 603  QVDEPALRELLPLRRADQDEYLCWAVKAFRLATSGVADSTQIHTHLCYSEFGEVIGAIAD 662

Query: 2059 MDADVITIENSRSDEKLLSVFREGVVYGAGIGPGVYDIHSPRIPSKEEIADRVNKMLAVL 2238
            +DADV +IE +RS  ++L      V +   IGPGVYDIHSPR+PS +EIA  +   L  +
Sbjct: 663  LDADVTSIEAARSHMEVLDDL-NAVGFANSIGPGVYDIHSPRVPSTDEIAKSLRAALKAI 721

Query: 2239 DTNILWVNPDCGLKTRKYAEVKPALTNMVEAAKQIRA 2349
                LWVNPDCGLKTR   EV  +L NMV AA+Q+RA
Sbjct: 722  PMQRLWVNPDCGLKTRSVDEVSASLQNMVAAARQVRA 758

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>Q87XJ9:METE_PSESM 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase|
            - Pseudomonas syringae pv. tomato
          Length = 766

 Score =  660 bits (1704), Expect = 0.0
 Identities = 373/771 (48%), Positives = 467/771 (60%), Gaps = 15/771 (1%)
 Frame = +1

Query: 79   SHIVGYPRMGPKRELKFALESFWDGKSSAEDLEKVATDLRASIWKQMAGAGIKYIPSNTF 258
            +H +G+PR+G  RELK ALE++W G      L  V   LRA+ W+    AGI+ +P   F
Sbjct: 4    AHNLGFPRIGADRELKKALEAYWKGDLDQTGLRAVGQQLRAAHWQVQKEAGIELLPVGDF 63

Query: 259  AYYDQVLDTTAMLGAVPDRYSWT---GGEINLSTYFSMARGNA---------TVPAMEMT 402
            A+YDQVL  +  LG +P+R+S      G   L T F+MARG +         T  A E+T
Sbjct: 64   AWYDQVLTHSLTLGVIPERFSPAQDAAGLPTLDTLFAMARGASNCCGASHGKTQHAQELT 123

Query: 403  KWFDTNYHFIVPELGPDTKFSYSSHKAINEYKEAKALGVDTVPVLVGPVSYLLLSKAAKG 582
            KWFDTNYH++VPE   D +F  S  +   E  EA ALG    PVL+GP++YL L KA KG
Sbjct: 124  KWFDTNYHYLVPEFTQDQRFQLSWEQLFEEVDEAHALGHKVKPVLIGPLTYLWLGKA-KG 182

Query: 583  VEKSFXXXXXXXXXXXVYKEVIAELKAAGASWIQFDEPTLVKDPESHQLAAFSAAYTELE 762
               SF           VY E++  L A G  W+QFDEP L  D       AF  AY  L+
Sbjct: 183  --DSFDRLELLDRLLPVYGEILGRLAAQGVEWVQFDEPVLTLDLPQDWKTAFERAYHSLQ 240

Query: 763  STLSGLNVLVETYFADVPAESYKTLTSLSSVTAYGFDLERGTKTLELVKSGFPAGKYLFA 942
               S L  LV TYF  +  E    L +   V     DL R  + L  V    P+ K L  
Sbjct: 241  --YSPLKKLVATYFGGL--EDNLGLAATLPVDGLHIDLVRAPEQLPAVLDRLPSYKVLSL 296

Query: 943  GVVDGRYIWADDLAASLATLQSLEAIVGKDKLVVSTSCSLMHTAVDLVNETKLDDEIKSW 1122
            GVV+GR +W  DL  +LA LQ   A  G D L V+ SCSL+H+ VDL  E +LD E+K W
Sbjct: 297  GVVNGRNVWRCDLDNALAALQQAHARFG-DNLWVAGSCSLLHSPVDLNREDRLDPELKGW 355

Query: 1123 LAFAAQKVVEVNALAKALAGQKDEXXXXXXXXXXXXXXXXXX---VTNEEVQKAATALKG 1293
            LAFA QK  E+  L+ AL   +                       V N +VQ    ++  
Sbjct: 356  LAFAVQKSREIAILSHALNDPEATEVVEALAQSCEIQASRAQSSRVHNPQVQARLASVTA 415

Query: 1294 SDHRRATTVSARLDAQQKKLNLPVLPTTTIGSFPQTVELRRVRREYKAKKISEEEYTNAI 1473
            +DH+R +  + R+  Q+++L LP  PTTTIGSFPQT  +R  R+ +K  K+S  +YT+A+
Sbjct: 416  ADHQRRSAFAERITVQRERLKLPAFPTTTIGSFPQTSAIRLARQAHKQGKLSLNDYTDAM 475

Query: 1474 KEEISKVVKIQEELDIDVLVHGEPERNDMVEYFGEQLSGFTFTANGWVQSYGSRCVKPPI 1653
            + EI   V++QE L +DVLVHGE ERNDMVEYF EQL G+ FT  GWVQSYGSRCVKP I
Sbjct: 476  RHEIRHAVQVQENLGLDVLVHGEAERNDMVEYFAEQLDGYLFTRFGWVQSYGSRCVKPAI 535

Query: 1654 IYGDVSRPNPMTVFWSKMAQSMTARPMKGMLTGPVTILNWSFVRNDQPRFETCYQIALAI 1833
            I+GD+SRP PMTV W + AQS+T + MKGMLTGPVT+L WSF R D  R     Q+ALAI
Sbjct: 536  IFGDLSRPQPMTVDWIRYAQSLTDKTMKGMLTGPVTMLMWSFSREDVSRQVQAQQLALAI 595

Query: 1834 KKEVEDLEAGGIQVIQIDEAALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDTTQIHTH 2013
            + EV DLE  GI+++QIDEAA REGLPLRK++   YLDWAV +FR+   GV+D TQIHTH
Sbjct: 596  RDEVLDLERAGIKIVQIDEAAFREGLPLRKAQWQQYLDWAVAAFRLCASGVRDETQIHTH 655

Query: 2014 MCYSNFNDIIQSIINMDADVITIENSRSDEKLLSVFREGVVYGAGIGPGVYDIHSPRIPS 2193
            MCYS FND+I+SI  MDADVITIE SRSD +LL  F E   Y   IGPGVYDIHSPR+P 
Sbjct: 656  MCYSEFNDVIKSIAAMDADVITIETSRSDMELLDAF-EAFDYPNDIGPGVYDIHSPRVPE 714

Query: 2194 KEEIADRVNKMLAVLDTNILWVNPDCGLKTRKYAEVKPALTNMVEAAKQIR 2346
              E+   + K    +    LWVNPDCGLKTR + E + AL NMV AA+Q+R
Sbjct: 715  TAEMVSLIAKAARRIPAERLWVNPDCGLKTRGWPETEAALINMVAAARQLR 765

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>Q83A62:METE_COXBU 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase|
            - Coxiella burnetii
          Length = 775

 Score =  659 bits (1701), Expect = 0.0
 Identities = 363/779 (46%), Positives = 476/779 (61%), Gaps = 6/779 (0%)
 Frame = +1

Query: 79   SHIVGYPRMGPKRELKFALESFWDGKSSAEDLEKVATDLRASIWKQMAGAGIKYIPSNTF 258
            +H +G+PR+G KRE+K  +E++W G+ S + L++ A +L+ + WK  A AG+  IP   F
Sbjct: 4    AHNLGFPRIGIKREMKKTVEAYWRGEISQQQLQQQAIELQLTNWKIQAEAGVDLIPVGDF 63

Query: 259  AYYDQVLDTTAMLGAVPDRYSWTGGEINLSTYFSMARGNAT----VPAMEMTKWFDTNYH 426
            ++YD VLD    +GA+P R+      I   T F MARG A       A EMTKWFDTNYH
Sbjct: 64   SWYDHVLDMAVRVGAIPSRFKALNSNIT-DTMFCMARGQAPNGIETSACEMTKWFDTNYH 122

Query: 427  FIVPELGPDTKFSYSSHKAINEYKEAKALGVDTVPVLVGPVSYLLLSKAAKGVEKSFXXX 606
            +IVPE   +  F           K A        PV++GP+S+L L K  KG  +SF   
Sbjct: 123  YIVPEFTTNQSFELHHDDLFKSTKLALENNYRAKPVILGPLSFLWLGKC-KG--ESFNKL 179

Query: 607  XXXXXXXXVYKEVIAELKAAGASWIQFDEPTLVKDPESHQLAAFSAAYTELESTLSGLNV 786
                    VY E+  +L + G  W+Q DEP LV D       AF   Y +L      L  
Sbjct: 180  LLLEKLLPVYAEIFEQLSSLGVEWVQVDEPILVLDLPPEWQQAFLTTYQQLN--FFNLKC 237

Query: 787  LVETYFADVPAESYKTLTSLSSVTAYGFDLERGTKTLELVKSGFPAGKYLFAGVVDGRYI 966
            L+ TYF  +  +   +LT    V     D  R    L+ V S  PA K L  G++DGR I
Sbjct: 238  LLATYFGSL--DDNLSLTCQLPVDGLHIDYCRAPDQLDSVLSQLPAEKILSVGIIDGRNI 295

Query: 967  WADDLAASLATLQSLEAIVGKDKLVVSTSCSLMHTAVDLVNETKLDDEIKSWLAFAAQKV 1146
            W +DL  SL  L+++++ +G D+L V+ SCSL+H  +DL  E KLD E+KSW AFA QKV
Sbjct: 296  WCNDLNRSLTLLENIQSSLG-DRLWVAPSCSLLHVPIDLDQENKLDVELKSWFAFAKQKV 354

Query: 1147 VEVNALAKALAGQKDEXXXXXXXXXXXXXXXXXX--VTNEEVQKAATALKGSDHRRATTV 1320
             E   L + L   ++                     + N  V+K A ++     RR    
Sbjct: 355  AEAAFLTRGLREGRESIGAELKKNEEVIISRKTSKRIHNPNVEKKAASVTERLMRRQHEH 414

Query: 1321 SARLDAQQKKLNLPVLPTTTIGSFPQTVELRRVRREYKAKKISEEEYTNAIKEEISKVVK 1500
            S R + Q  +LNLP+ PTTTIGSFPQT ++R +RR+YK  KI +  Y   I++EI++V+ 
Sbjct: 415  SIRKNKQTAQLNLPLFPTTTIGSFPQTSQIRCLRRDYKQGKIDDALYEEKIRQEIAEVIG 474

Query: 1501 IQEELDIDVLVHGEPERNDMVEYFGEQLSGFTFTANGWVQSYGSRCVKPPIIYGDVSRPN 1680
            IQ +L +DVLVHGEPERNDMVEYFGE L G   T+NGWVQSYGSRCVKPPII+GDVSR  
Sbjct: 475  IQVKLGLDVLVHGEPERNDMVEYFGELLDGIAITSNGWVQSYGSRCVKPPIIFGDVSRER 534

Query: 1681 PMTVFWSKMAQSMTARPMKGMLTGPVTILNWSFVRNDQPRFETCYQIALAIKKEVEDLEA 1860
            PMT+ W + AQS+T + +KGMLTGPVTIL WSFVR+DQPR +T  QIALA++ EV+DLE 
Sbjct: 535  PMTLRWIEYAQSLTTKSVKGMLTGPVTILAWSFVRDDQPRSQTAKQIALALRDEVQDLER 594

Query: 1861 GGIQVIQIDEAALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDTTQIHTHMCYSNFNDI 2040
             G++VIQIDE A RE LPLRK+    YL+WAV  FR+ +CGV+D TQIHTHMCYS FNDI
Sbjct: 595  SGVRVIQIDEPAFRECLPLRKAAWQDYLEWAVKCFRLASCGVKDETQIHTHMCYSEFNDI 654

Query: 2041 IQSIINMDADVITIENSRSDEKLLSVFREGVVYGAGIGPGVYDIHSPRIPSKEEIADRVN 2220
            I++I  +DADVITIE+SRS+ ++L  F E   Y   IGPG+YDIHSPRIP   EI +   
Sbjct: 655  IEAIAALDADVITIESSRSEMEILKSF-EKFAYPNDIGPGIYDIHSPRIPRVAEIEELAV 713

Query: 2221 KMLAVLDTNILWVNPDCGLKTRKYAEVKPALTNMVEAAKQIRAELAKAQ*AVLV*QLSP 2397
            + L  +    LW+NPDCGLKTR + E K AL+ MV+AAK +R   +  +   +  +L P
Sbjct: 714  RALQYIPIERLWINPDCGLKTRNWEETKEALSRMVDAAKHLRKAFSSEKTPTIDLELQP 772

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>P57843:METE_PASMU 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase|
            - Pasteurella multocida
          Length = 757

 Score =  657 bits (1695), Expect = 0.0
 Identities = 365/763 (47%), Positives = 472/763 (61%), Gaps = 5/763 (0%)
 Frame = +1

Query: 82   HIVGYPRMGPKRELKFALESFWDGKSSAEDLEKVATDLRASIWKQMAGAGIKYIPSNTFA 261
            H+ G+PR+G KRELKFA E +W G+ + +DL ++A  LR   WK  A A   ++    F 
Sbjct: 5    HVAGFPRVGAKRELKFAQERYWRGEIAEQDLLEIAQKLREINWKHQAAANADFVAVADFT 64

Query: 262  YYDQVLDTTAMLGAVPDRYSWTGGEINLSTYFSMARGNATVPAMEMTKWFDTNYHFIVPE 441
            +YD +LD     GA+P R+ +    ++L+ YF +ARGN T  A+EMTKWFDTNYH++VPE
Sbjct: 65   FYDHILDLQVATGAIPARFGFDSQNLSLNEYFQLARGNQTQFAIEMTKWFDTNYHYLVPE 124

Query: 442  LGPDTKFSYSSHKAINEYKEAKALGVDTVPVLVGPVSYLLLSKAAKGVEKSFXXXXXXXX 621
               +T+F  +    + + +EAKALG    P +VGP+++L L K  KG  ++F        
Sbjct: 125  FTKNTEFKANPAHYVQQIREAKALGFKFKPTIVGPLTFLWLGKE-KG--EAFNRFELLAK 181

Query: 622  XXXVYKEVIAELKAAGASWIQFDEPTLVKDPESHQLAAFSAAYTELESTLSGLNVLVETY 801
               VY E++  L A GA WIQ DEP L  D  +  + A+ A YT L+  +    +L+ TY
Sbjct: 182  LVPVYVEILNALVAEGAEWIQIDEPALAVDLPTEWIEAYKAVYTTLKEKVKA-KLLLATY 240

Query: 802  FADVPAESYKTLTSLSSVTAYGFDLERGTKTLELVKSGFPAGKYLFAGVVDGRYIWADDL 981
            F  V AE    L  L  V     DL R    L   +      K L  GV+DGR IW  +L
Sbjct: 241  FGSV-AEHAPLLKGLP-VDGLHIDLVRAPAQLAAFED---YNKVLSVGVIDGRNIWRANL 295

Query: 982  AASLATLQSLEAIVGKDKLVVSTSCSLMHTAVDLVNETKLD---DEIKSWLAFAAQKVVE 1152
               L  ++ L+A  G++ L ++ SCSL+HT  DL  ET+L     E+ SWLAF  QKV E
Sbjct: 296  NQVLDVVEPLKAKFGEN-LWIAPSCSLLHTPYDLEVETQLKANKPELYSWLAFTLQKVQE 354

Query: 1153 VNALAKALAGQKD--EXXXXXXXXXXXXXXXXXXVTNEEVQKAATALKGSDHRRATTVSA 1326
            +  +  AL   +   +                  +   EV +    L     +R +  + 
Sbjct: 355  LRVIKTALEQGRGAVQAELDASQAAADARANSKEIHRPEVAERLANLPTDADKRKSPFAE 414

Query: 1327 RLDAQQKKLNLPVLPTTTIGSFPQTVELRRVRREYKAKKISEEEYTNAIKEEISKVVKIQ 1506
            R+  Q   LNLP+LPTT IGSFPQTVE+R+ R ++K  ++S  +Y  A+K+EI  VV+ Q
Sbjct: 415  RIAKQNAWLNLPLLPTTNIGSFPQTVEIRQARAKFKKGELSVADYEAAMKKEIEFVVRRQ 474

Query: 1507 EELDIDVLVHGEPERNDMVEYFGEQLSGFTFTANGWVQSYGSRCVKPPIIYGDVSRPNPM 1686
            EELD+DVLVHGE ERNDMVEYFGE L GF FT  GWVQSYGSRCVKPP+IYGDV RP PM
Sbjct: 475  EELDLDVLVHGEAERNDMVEYFGELLDGFAFTKFGWVQSYGSRCVKPPVIYGDVVRPEPM 534

Query: 1687 TVFWSKMAQSMTARPMKGMLTGPVTILNWSFVRNDQPRFETCYQIALAIKKEVEDLEAGG 1866
            TV WS+ AQS+T + MKGMLTGPVTIL WSFVRND PR   C QI +A+  EV DLE  G
Sbjct: 535  TVRWSQYAQSLTNKVMKGMLTGPVTILQWSFVRNDIPRSTVCKQIGVALSDEVLDLEKAG 594

Query: 1867 IQVIQIDEAALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDTTQIHTHMCYSNFNDIIQ 2046
            I+VIQIDE A+REGLPL++++   YL WA  +FR++  GVQD TQIHTHMCYS FNDI+ 
Sbjct: 595  IKVIQIDEPAIREGLPLKRADWDAYLQWAGEAFRLSYMGVQDDTQIHTHMCYSEFNDILP 654

Query: 2047 SIINMDADVITIENSRSDEKLLSVFREGVVYGAGIGPGVYDIHSPRIPSKEEIADRVNKM 2226
            +I  +DADVITIE SRSD +LL+ F +   Y   IGPGVYDIHSPR+P  EEI   + K 
Sbjct: 655  AIAGLDADVITIETSRSDMELLTAFGD-FKYPNDIGPGVYDIHSPRVPKAEEIERLLRKA 713

Query: 2227 LAVLDTNILWVNPDCGLKTRKYAEVKPALTNMVEAAKQIRAEL 2355
            L V+    LWVNPDCGLKTR + E    L  M+E  K++RAEL
Sbjct: 714  LNVVPKERLWVNPDCGLKTRGWPETIAQLEVMMEVTKKLRAEL 756

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>Q87NA1:METE_VIBPA 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase|
            - Vibrio parahaemolyticus
          Length = 760

 Score =  657 bits (1694), Expect = 0.0
 Identities = 367/770 (47%), Positives = 470/770 (61%), Gaps = 10/770 (1%)
 Frame = +1

Query: 79   SHIVGYPRMGPKRELKFALESFWDGKSSAEDLEKVATDLRASIWKQMAGAGIKYIPSNTF 258
            +HI+GYPR+G KRELKFA E +W G     +L+KV  DLRA  W+    AG+ +  +  F
Sbjct: 5    THILGYPRIGEKRELKFAQEKYWRGDIDQTELKKVGADLRAKNWQTQTEAGLSFTTAGDF 64

Query: 259  AYYDQVLDTTAMLGAVPDRYSWTGGEINLSTYFSMARGN-------ATVPAMEMTKWFDT 417
            A+YD VL TT +LG VP R++  GG  NL T F + RG        A   A +MTKWF+T
Sbjct: 65   AWYDHVLTTTLLLGHVPKRHA--GGFPNLDTLFKVGRGQSQAGCGCAGAAASDMTKWFNT 122

Query: 418  NYHFIVPELGPDTKFSYSSHKAINEYKEAKALGVDTVPVLVGPVSYLLLSKAAKGVEKSF 597
            NYH+IVPE   D  F  S  +   E  EA   G    PVL+GPVSYL L K    VE+ F
Sbjct: 123  NYHYIVPEFSKDDTFEVSWPQLFEEINEAVQAGHKVKPVLLGPVSYLYLGKE---VEEGF 179

Query: 598  XXXXXXXXXXXVYKEVIAELKAAGASWIQFDEPTLVKDPESHQLAAFSAAYTELESTLSG 777
                        Y+ ++A+L + G  W+Q DEP L  + E     AF  AY  + S +  
Sbjct: 180  DRLTLLPRLLTAYQAILAKLASQGVEWVQIDEPILSLELEKQWADAFKLAYQLIRSDVK- 238

Query: 778  LNVLVETYFADVPAESYKTLTSLSSVTAYGF--DLERGTKTLELVKSGFPAGKYLFAGVV 951
              VL+ TYF  V      TL  +  +   G   DL    + L+ V +  P G  L AGVV
Sbjct: 239  --VLLTTYFDSVT----DTLDKIVELPVDGLHVDLSAAPQQLDDVVAKLPEGWVLSAGVV 292

Query: 952  DGRYIWADDLAASLATLQSLEAIVGKDKLVVSTSCSLMHTAVDLVNETKLDDEIKSWLAF 1131
            +GR +W  DL+A L  LQ ++  +G DKL V++SCSL+H+ VDL  ET+L +E+KSW AF
Sbjct: 293  NGRNVWRSDLSAQLERLQPVKEKLG-DKLWVASSCSLLHSPVDLELETELSEEVKSWFAF 351

Query: 1132 AAQKVVEVNALAKALAGQKDEXXXXXXXXXXXXXXXXXXVTNE-EVQKAATALKGSDHRR 1308
            A QKV EV  L +AL G ++                     N+ +VQ     +  S   R
Sbjct: 352  AKQKVTEVALLGRALDGDQNAILACDTYSQPIKARKTATHVNKPQVQVRLNNITASLAER 411

Query: 1309 ATTVSARLDAQQKKLNLPVLPTTTIGSFPQTVELRRVRREYKAKKISEEEYTNAIKEEIS 1488
            +   + R   Q + L LP+LPTTTIGSFPQT E+R  R  Y+  ++SE +Y  A+K  I+
Sbjct: 412  SAPYAERAAHQAEVLGLPLLPTTTIGSFPQTGEIRVQRSAYRTGQLSESDYIQALKGHIA 471

Query: 1489 KVVKIQEELDIDVLVHGEPERNDMVEYFGEQLSGFTFTANGWVQSYGSRCVKPPIIYGDV 1668
              VK QE LD+DVLVHGE ERNDMVEYF E L+GF  T  GWVQSYGSRCVKP I+  D+
Sbjct: 472  DAVKRQEALDLDVLVHGEAERNDMVEYFAENLAGFQTTKFGWVQSYGSRCVKPAIVVADI 531

Query: 1669 SRPNPMTVFWSKMAQSMTARPMKGMLTGPVTILNWSFVRNDQPRFETCYQIALAIKKEVE 1848
             R  P+TV WS  AQS+T++ MKGMLTGPVTIL W+F R D  R E   Q+ALA++ EV 
Sbjct: 532  EREKPITVEWSTYAQSLTSKQMKGMLTGPVTILCWTFPREDITRQEIAQQLALALRDEVS 591

Query: 1849 DLEAGGIQVIQIDEAALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDTTQIHTHMCYSN 2028
            DL+  GI +IQIDE A+REGLPL+K +H  YL+WAV++F+I+    +  TQIHTHMCYS 
Sbjct: 592  DLQDAGINIIQIDEPAIREGLPLKKRDHKAYLEWAVNAFKISAASAKPETQIHTHMCYSE 651

Query: 2029 FNDIIQSIINMDADVITIENSRSDEKLLSVFREGVVYGAGIGPGVYDIHSPRIPSKEEIA 2208
            FN+II S+  +DADVITIE SRS+ +LL  F E   Y   IGPGVYDIHSP IP++E I 
Sbjct: 652  FNEIIDSVAALDADVITIETSRSNMELLKAFEE-FNYPNEIGPGVYDIHSPNIPTEEWIE 710

Query: 2209 DRVNKMLAVLDTNILWVNPDCGLKTRKYAEVKPALTNMVEAAKQIRAELA 2358
              + K    +    LWVNPDCGLKTR +AE + AL N+V AAK++RAELA
Sbjct: 711  GLIKKAAEKIPVQRLWVNPDCGLKTRNWAETEAALANLVSAAKKLRAELA 760

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>Q8FBM1:METE_ECOL6 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase|
            - Escherichia coli O6
          Length = 753

 Score =  648 bits (1672), Expect = 0.0
 Identities = 362/760 (47%), Positives = 459/760 (60%), Gaps = 4/760 (0%)
 Frame = +1

Query: 79   SHIVGYPRMGPKRELKFALESFWDGKSSAEDLEKVATDLRASIWKQMAGAGIKYIPSNTF 258
            +H +G+PR+G +RELK A ES+W G S+ E+L  V  +LRA  W Q   AGI  +P   F
Sbjct: 5    NHTLGFPRVGLRRELKKAQESYWAGNSTREELLAVGRELRARHWDQQKQAGIDLLPVGDF 64

Query: 259  AYYDQVLDTTAMLGAVPDRYSWTGGEINLSTYFSMARGNATV----PAMEMTKWFDTNYH 426
            A+YD VL T+ +LG VP R+    G +++ T F + RG A       A EMTKWF+TNYH
Sbjct: 65   AWYDHVLTTSLLLGNVPPRHQNKDGSVDIDTLFRIGRGRAPTGEPAAAAEMTKWFNTNYH 124

Query: 427  FIVPELGPDTKFSYSSHKAINEYKEAKALGVDTVPVLVGPVSYLLLSKAAKGVEKSFXXX 606
            ++VPE     +F  +  + + E  EA ALG    PVL+GP++YL L K  KG  + F   
Sbjct: 125  YMVPEFVKGQQFKLTWTQLLEEVDEALALGHKVKPVLLGPITYLWLGKV-KG--EQFDRL 181

Query: 607  XXXXXXXXVYKEVIAELKAAGASWIQFDEPTLVKDPESHQLAAFSAAYTELESTLSGLNV 786
                    VY++V+AEL   G  W+Q DEP LV +     L A+  AY  L+  +    +
Sbjct: 182  SLLNDILPVYQQVLAELAKRGIEWVQIDEPALVLELPQAWLDAYKPAYDALQGQVK---L 238

Query: 787  LVETYFADVPAESYKTLTSLSSVTAYGFDLERGTKTLELVKSGFPAGKYLFAGVVDGRYI 966
            L+ TYF  V   +  T+T+L  V     DL  G   +  +    P+   L AG+++GR +
Sbjct: 239  LLTTYFEGV-TPNLDTITALP-VQGLHVDLVHGKDDVAELHKRLPSDWLLSAGLINGRNV 296

Query: 967  WADDLAASLATLQSLEAIVGKDKLVVSTSCSLMHTAVDLVNETKLDDEIKSWLAFAAQKV 1146
            W  DL    A ++    IVGK  L V++SCSL+H+ +DL  ET+LD E+KSW AFA QK 
Sbjct: 297  WRADLTEKYAQIKD---IVGKRDLWVASSCSLLHSPIDLSVETRLDAEVKSWFAFALQKC 353

Query: 1147 VEVNALAKALAGQKDEXXXXXXXXXXXXXXXXXXVTNEEVQKAATALKGSDHRRATTVSA 1326
             E+  L  AL    D                   V N  V+K   A+   D +RA     
Sbjct: 354  HELALLRDAL-NSGDTAALAEWSAPIQARRHSTRVHNPAVEKRLAAITAQDSQRANVYEV 412

Query: 1327 RLDAQQKKLNLPVLPTTTIGSFPQTVELRRVRREYKAKKISEEEYTNAIKEEISKVVKIQ 1506
            R +AQ+ +  LP  PTTTIGSFPQT E+R +R ++K   +    Y   I E I + +  Q
Sbjct: 413  RAEAQRARFKLPAWPTTTIGSFPQTTEIRTLRLDFKKGNLDANNYRTGIAEHIKQAIVEQ 472

Query: 1507 EELDIDVLVHGEPERNDMVEYFGEQLSGFTFTANGWVQSYGSRCVKPPIIYGDVSRPNPM 1686
            E L +DVLVHGE ERNDMVEYFGE L GF FT NGWVQSYGSRCVKPPI+ GDVSRP P+
Sbjct: 473  ERLGLDVLVHGEAERNDMVEYFGEHLDGFVFTQNGWVQSYGSRCVKPPIVIGDVSRPAPI 532

Query: 1687 TVFWSKMAQSMTARPMKGMLTGPVTILNWSFVRNDQPRFETCYQIALAIKKEVEDLEAGG 1866
            TV W+K AQS+T +P+KGMLTGPVTIL WSF R D  R     QIALA++ EV DLEA G
Sbjct: 533  TVEWAKYAQSLTDKPVKGMLTGPVTILCWSFPREDVSRETIAKQIALALRDEVADLEAAG 592

Query: 1867 IQVIQIDEAALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDTTQIHTHMCYSNFNDIIQ 2046
            I +IQIDE ALREGLPLR+S+   YL W V +FRI     +D TQIHTHMCY  FNDI+ 
Sbjct: 593  IGIIQIDEPALREGLPLRRSDWDAYLQWGVEAFRINAAVAKDDTQIHTHMCYCEFNDIMD 652

Query: 2047 SIINMDADVITIENSRSDEKLLSVFREGVVYGAGIGPGVYDIHSPRIPSKEEIADRVNKM 2226
            SI  +DADVITIE SRSD +LL  F E   Y   IGPGVYDIHSP +PS E I   + K 
Sbjct: 653  SIAALDADVITIETSRSDMELLESFEE-FDYPNEIGPGVYDIHSPNVPSVEWIEALLKKA 711

Query: 2227 LAVLDTNILWVNPDCGLKTRKYAEVKPALTNMVEAAKQIR 2346
               +    LWVNPDCGLKTR + E + AL NMV+AA+ +R
Sbjct: 712  AKRIPAERLWVNPDCGLKTRGWPETRAALANMVQAAQNLR 751

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>P57703:METE_PSEAE 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase|
            - Pseudomonas aeruginosa
          Length = 766

 Score =  647 bits (1669), Expect = 0.0
 Identities = 366/773 (47%), Positives = 465/773 (60%), Gaps = 12/773 (1%)
 Frame = +1

Query: 79   SHIVGYPRMGPKRELKFALESFWDGKSSAEDLEKVATDLRASIWKQMAGAGIKYIPSNTF 258
            +H +G+PR+G  RELK A E+FW G+     L  V   LRA+ W+    AGI+ +P   F
Sbjct: 4    AHTLGFPRIGRDRELKKAQEAFWKGELDEAGLRAVGRQLRAAHWQVQKDAGIQLLPVGDF 63

Query: 259  AYYDQVLDTTAMLGAVPDRYSWTG-GEINLSTYFSMARGNAT------VPAMEMTKWFDT 417
            A+YDQVL  +   G +P+R+   G     L T F MARG +         A EMTKWFDT
Sbjct: 64   AWYDQVLTHSLTFGVIPERFRAHGEAGPTLHTLFGMARGVSDDSCCGGAHAQEMTKWFDT 123

Query: 418  NYHFIVPELGPDTKFSYSSHKAINEYKEAKALGVDTVPVLVGPVSYLLLSKAAKGVEKSF 597
            NYH++VPE   D +F  S  +   E  EA+ALG    PVL+GP++YL L KA KG E  F
Sbjct: 124  NYHYLVPEFSADQQFQLSWEQLFEEVDEARALGHQVKPVLIGPLTYLWLGKA-KGAE--F 180

Query: 598  XXXXXXXXXXXVYKEVIAELKAAGASWIQFDEPTLVKDPESHQLAAFSAAYTELESTLSG 777
                       +Y ++   L   G  W+Q DEP LV D       AF  AY  L+S    
Sbjct: 181  DRLDLLDRLLPLYGQIFRRLAGQGVEWVQIDEPILVLDLPQAWKNAFERAYNLLQS--EP 238

Query: 778  LNVLVETYFADVPAESYKTLTSLSSVTAYGFDLERGTKTLELVKSGFPAGKYLFAGVVDG 957
            L  LV TYF  +  E    L +   V     DL R  +    +    PA K +  G+V+G
Sbjct: 239  LKKLVATYFGGL--EDNLGLAANLPVDGLHIDLVRAPEQYPSILDRLPAYKVVSLGLVNG 296

Query: 958  RYIWADDLAASLATLQSLEAIVGKDKLVVSTSCSLMHTAVDLVNETKLDDEIKSWLAFAA 1137
            R +W  DL  +L  ++     +G ++L V+ SCSL+H+ VDL  E  LD E+KSWLAFA 
Sbjct: 297  RNVWRCDLEKALEVVRHARERLG-ERLWVAPSCSLLHSPVDLEREDGLDAELKSWLAFAV 355

Query: 1138 QKVVEVNALAKALAGQKDEXXXXXXXXXXXXXXXXXXVTNEEVQKAAT-----ALKGSDH 1302
            QK  EV  LA+A    + E                   ++  + K A      A+K SD 
Sbjct: 356  QKCREVAVLARAAT--EPEAAEVLAALEESRAVQASRASSPRIHKPAVQARLAAIKASDA 413

Query: 1303 RRATTVSARLDAQQKKLNLPVLPTTTIGSFPQTVELRRVRREYKAKKISEEEYTNAIKEE 1482
            +R +  + R+  Q+  L+LP  PTTTIGSFPQT  +R  R+ +K  K+SE EY  A+  E
Sbjct: 414  QRRSPFAERIARQRAGLDLPAFPTTTIGSFPQTSSIRLARQSFKQGKLSEAEYIEAMHSE 473

Query: 1483 ISKVVKIQEELDIDVLVHGEPERNDMVEYFGEQLSGFTFTANGWVQSYGSRCVKPPIIYG 1662
            I   V+IQE+L +DVLVHGE ERNDMVEYF EQL G+ FT  GWVQSYGSRCVKP +IYG
Sbjct: 474  IRHAVQIQEQLGLDVLVHGEAERNDMVEYFAEQLDGYVFTRFGWVQSYGSRCVKPAVIYG 533

Query: 1663 DVSRPNPMTVFWSKMAQSMTARPMKGMLTGPVTILNWSFVRNDQPRFETCYQIALAIKKE 1842
            D+SRP  MTV W + AQS+T + MKGMLTGPVT+L WSF R D  R     Q+ALAI+ E
Sbjct: 534  DLSRPRAMTVEWIRYAQSLTDKVMKGMLTGPVTMLMWSFPREDVSREVQARQLALAIRDE 593

Query: 1843 VEDLEAGGIQVIQIDEAALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDTTQIHTHMCY 2022
            V DLEA GI+++QIDEAA REGLPLR++    YL+WA  +FR+   GV+D TQIHTHMCY
Sbjct: 594  VVDLEAAGIRIVQIDEAAFREGLPLRRNAWPHYLEWATEAFRLCASGVRDETQIHTHMCY 653

Query: 2023 SNFNDIIQSIINMDADVITIENSRSDEKLLSVFREGVVYGAGIGPGVYDIHSPRIPSKEE 2202
            S FND+I+SI  MDADVITIE SRSD +LL  F E   Y   IGPGVYDIHSPR+PS+EE
Sbjct: 654  SEFNDVIESIAAMDADVITIETSRSDMELLEAF-EQFDYPNEIGPGVYDIHSPRVPSREE 712

Query: 2203 IADRVNKMLAVLDTNILWVNPDCGLKTRKYAEVKPALTNMVEAAKQIRAELAK 2361
            I   + K    +    LWVNPDCGLKTR + E + AL NMV AA+++R +LA+
Sbjct: 713  IVALLRKAARRIPAERLWVNPDCGLKTRAWPETEAALVNMVAAARELRGDLAR 765

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>Q83IW0:METE_SHIFL 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase|
            - Shigella flexneri
          Length = 753

 Score =  647 bits (1668), Expect = 0.0
 Identities = 361/760 (47%), Positives = 459/760 (60%), Gaps = 4/760 (0%)
 Frame = +1

Query: 79   SHIVGYPRMGPKRELKFALESFWDGKSSAEDLEKVATDLRASIWKQMAGAGIKYIPSNTF 258
            +H +G+PR+G +RELK A ES+W G S+ E+L  V  +LRA  W Q   AGI  +P   F
Sbjct: 5    NHTLGFPRVGLRRELKKAQESYWAGNSTREELLTVGRELRARHWDQQKQAGIDLLPVGDF 64

Query: 259  AYYDQVLDTTAMLGAVPDRYSWTGGEINLSTYFSMARGNATV----PAMEMTKWFDTNYH 426
            A+YD VL T+ +LG VP R+    G +++ T F + RG A       A EMTKWF+TNYH
Sbjct: 65   AWYDHVLTTSLLLGNVPPRHQNKDGSVDIDTLFRIGRGRAPTGEPAAAAEMTKWFNTNYH 124

Query: 427  FIVPELGPDTKFSYSSHKAINEYKEAKALGVDTVPVLVGPVSYLLLSKAAKGVEKSFXXX 606
            ++VPE     +F  +  + + E  EA AL  +  PVL+GPV+YL L K  KG  + F   
Sbjct: 125  YMVPEFVKGQQFKLTWTQLLEEVDEALALSHNVKPVLLGPVTYLWLGKV-KG--EQFDRL 181

Query: 607  XXXXXXXXVYKEVIAELKAAGASWIQFDEPTLVKDPESHQLAAFSAAYTELESTLSGLNV 786
                    VY++V+AEL   G  W+Q DEP LV +     L A+  AY  L+  +    +
Sbjct: 182  SLLNDILPVYQQVLAELAKRGIEWVQIDEPALVLELPQAWLDAYKPAYDALQGQVK---L 238

Query: 787  LVETYFADVPAESYKTLTSLSSVTAYGFDLERGTKTLELVKSGFPAGKYLFAGVVDGRYI 966
            L+ TYF  V   +  T+T+L  V     DL  G   +  +    P+   L AG+++GR +
Sbjct: 239  LLTTYFEGV-TPNLDTITALP-VQGLHVDLVHGKDNVVELHKRLPSDWLLSAGLINGRNV 296

Query: 967  WADDLAASLATLQSLEAIVGKDKLVVSTSCSLMHTAVDLVNETKLDDEIKSWLAFAAQKV 1146
            W  DL    A ++    IVGK  L V++SCSL+H+ +DL  ET+LD E+KSW AFA QK 
Sbjct: 297  WRADLTEKYAQIKD---IVGKRDLWVASSCSLLHSPIDLSVETRLDAEVKSWFAFALQKC 353

Query: 1147 VEVNALAKALAGQKDEXXXXXXXXXXXXXXXXXXVTNEEVQKAATALKGSDHRRATTVSA 1326
             E+  L  AL    D                   V N  V+K   A+   D +RA     
Sbjct: 354  HELALLRDAL-NSGDTAALAEWSAPIQARRHSTRVHNPAVEKRLAAITAQDSQRANVYEV 412

Query: 1327 RLDAQQKKLNLPVLPTTTIGSFPQTVELRRVRREYKAKKISEEEYTNAIKEEISKVVKIQ 1506
            R +AQ+ +  LP  PTTTIGSFPQT E+R +R ++K   +    Y   I E I + +  Q
Sbjct: 413  RAEAQRARFKLPAWPTTTIGSFPQTTEIRTLRLDFKKGNLDANNYRTGIAEHIKQAIVEQ 472

Query: 1507 EELDIDVLVHGEPERNDMVEYFGEQLSGFTFTANGWVQSYGSRCVKPPIIYGDVSRPNPM 1686
            E L +DVLVHGE ERNDMVEYFGE L GF FT NGWVQSYGSRCVKPPI+ GD+SRP P+
Sbjct: 473  ERLGLDVLVHGEAERNDMVEYFGEHLDGFVFTQNGWVQSYGSRCVKPPIVIGDISRPAPI 532

Query: 1687 TVFWSKMAQSMTARPMKGMLTGPVTILNWSFVRNDQPRFETCYQIALAIKKEVEDLEAGG 1866
            TV W+K AQS+T +P+KGMLTGPVTIL WSF R D  R     QIALA++ EV DLEA G
Sbjct: 533  TVEWAKYAQSLTDKPVKGMLTGPVTILCWSFPREDVSRETIAKQIALALRDEVADLEAAG 592

Query: 1867 IQVIQIDEAALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDTTQIHTHMCYSNFNDIIQ 2046
            I +IQIDE ALREGLPLR+S+   YL W V +FRI     +D TQIHTHMCY  FNDI+ 
Sbjct: 593  IGIIQIDEPALREGLPLRRSDWDAYLQWGVEAFRINAAVAKDDTQIHTHMCYCEFNDIMD 652

Query: 2047 SIINMDADVITIENSRSDEKLLSVFREGVVYGAGIGPGVYDIHSPRIPSKEEIADRVNKM 2226
            SI  +DADVITIE SRSD +LL  F E   Y   IGPGVYDIHSP +PS E I   + K 
Sbjct: 653  SIAALDADVITIETSRSDMELLESFEE-FDYPNEIGPGVYDIHSPNVPSVEWIEALLKKA 711

Query: 2227 LAVLDTNILWVNPDCGLKTRKYAEVKPALTNMVEAAKQIR 2346
               +    LWVNPDCGLKTR + E + AL NMV+AA+ +R
Sbjct: 712  AKRIPAERLWVNPDCGLKTRGWPETRAALANMVQAAQNLR 751

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>P25665:METE_ECOLI 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase|
            - Escherichia coli
          Length = 753

 Score =  646 bits (1667), Expect = 0.0
 Identities = 361/760 (47%), Positives = 460/760 (60%), Gaps = 4/760 (0%)
 Frame = +1

Query: 79   SHIVGYPRMGPKRELKFALESFWDGKSSAEDLEKVATDLRASIWKQMAGAGIKYIPSNTF 258
            +H +G+PR+G +RELK A ES+W G S+ E+L  V  +LRA  W Q   AGI  +P   F
Sbjct: 5    NHTLGFPRVGLRRELKKAQESYWAGNSTREELLAVGRELRARHWDQQKQAGIDLLPVGDF 64

Query: 259  AYYDQVLDTTAMLGAVPDRYSWTGGEINLSTYFSMARGNATV----PAMEMTKWFDTNYH 426
            A+YD VL T+ +LG VP R+    G +++ T F + RG A       A EMTKWF+TNYH
Sbjct: 65   AWYDHVLTTSLLLGNVPARHQNKDGSVDIDTLFRIGRGRAPTGEPAAAAEMTKWFNTNYH 124

Query: 427  FIVPELGPDTKFSYSSHKAINEYKEAKALGVDTVPVLVGPVSYLLLSKAAKGVEKSFXXX 606
            ++VPE     +F  +  + ++E  EA ALG    PVL+GPV++L L K  KG  + F   
Sbjct: 125  YMVPEFVKGQQFKLTWTQLLDEVDEALALGHKVKPVLLGPVTWLWLGKV-KG--EQFDRL 181

Query: 607  XXXXXXXXVYKEVIAELKAAGASWIQFDEPTLVKDPESHQLAAFSAAYTELESTLSGLNV 786
                    VY++V+AEL   G  W+Q DEP LV +     L A+  AY  L+  +    +
Sbjct: 182  SLLNDILPVYQQVLAELAKRGIEWVQIDEPALVLELPQAWLDAYKPAYDALQGQVK---L 238

Query: 787  LVETYFADVPAESYKTLTSLSSVTAYGFDLERGTKTLELVKSGFPAGKYLFAGVVDGRYI 966
            L+ TYF  V   +  T+T+L  V     DL  G   +  +    P+   L AG+++GR +
Sbjct: 239  LLTTYFEGV-TPNLDTITALP-VQGLHVDLVHGKDDVAELHKRLPSDWLLSAGLINGRNV 296

Query: 967  WADDLAASLATLQSLEAIVGKDKLVVSTSCSLMHTAVDLVNETKLDDEIKSWLAFAAQKV 1146
            W  DL    A ++    IVGK  L V++SCSL+H+ +DL  ET+LD E+KSW AFA QK 
Sbjct: 297  WRADLTEKYAQIKD---IVGKRDLWVASSCSLLHSPIDLSVETRLDAEVKSWFAFALQKC 353

Query: 1147 VEVNALAKALAGQKDEXXXXXXXXXXXXXXXXXXVTNEEVQKAATALKGSDHRRATTVSA 1326
             E+  L  AL    D                   V N  V+K   A+   D +RA     
Sbjct: 354  HELALLRDAL-NSGDTAALAEWSAPIQARRHSTRVHNPAVEKRLAAITAQDSQRANVYEV 412

Query: 1327 RLDAQQKKLNLPVLPTTTIGSFPQTVELRRVRREYKAKKISEEEYTNAIKEEISKVVKIQ 1506
            R +AQ+ +  LP  PTTTIGSFPQT E+R +R ++K   +    Y   I E I + +  Q
Sbjct: 413  RAEAQRARFKLPAWPTTTIGSFPQTTEIRTLRLDFKKGNLDANNYRTGIAEHIKQAIVEQ 472

Query: 1507 EELDIDVLVHGEPERNDMVEYFGEQLSGFTFTANGWVQSYGSRCVKPPIIYGDVSRPNPM 1686
            E L +DVLVHGE ERNDMVEYFGE L GF FT NGWVQSYGSRCVKPPI+ GD+SRP P+
Sbjct: 473  ERLGLDVLVHGEAERNDMVEYFGEHLDGFVFTQNGWVQSYGSRCVKPPIVIGDISRPAPI 532

Query: 1687 TVFWSKMAQSMTARPMKGMLTGPVTILNWSFVRNDQPRFETCYQIALAIKKEVEDLEAGG 1866
            TV W+K AQS+T +P+KGMLTGPVTIL WSF R D  R     QIALA++ EV DLEA G
Sbjct: 533  TVEWAKYAQSLTDKPVKGMLTGPVTILCWSFPREDVSRETIAKQIALALRDEVADLEAAG 592

Query: 1867 IQVIQIDEAALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDTTQIHTHMCYSNFNDIIQ 2046
            I +IQIDE ALREGLPLR+S+   YL W V +FRI     +D TQIHTHMCY  FNDI+ 
Sbjct: 593  IGIIQIDEPALREGLPLRRSDWDAYLQWGVEAFRINAAVAKDDTQIHTHMCYCEFNDIMD 652

Query: 2047 SIINMDADVITIENSRSDEKLLSVFREGVVYGAGIGPGVYDIHSPRIPSKEEIADRVNKM 2226
            SI  +DADVITIE SRSD +LL  F E   Y   IGPGVYDIHSP +PS E I   + K 
Sbjct: 653  SIAALDADVITIETSRSDMELLESFEE-FDYPNEIGPGVYDIHSPNVPSVEWIEALLKKA 711

Query: 2227 LAVLDTNILWVNPDCGLKTRKYAEVKPALTNMVEAAKQIR 2346
               +    LWVNPDCGLKTR + E + AL NMV+AA+ +R
Sbjct: 712  AKRIPAERLWVNPDCGLKTRGWPETRAALANMVQAAQNLR 751

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>P57142:METE_BUCAI 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase|
            - Buchnera aphidicola subsp. Acyrthosiphon pisum
            (Acyrthosiphon pisum symbiotic bacterium)
          Length = 758

 Score =  646 bits (1667), Expect = 0.0
 Identities = 358/764 (46%), Positives = 468/764 (61%), Gaps = 1/764 (0%)
 Frame = +1

Query: 79   SHIVGYPRMGPKRELKFALESFWDGKSSAEDLEKVATDLRASIWKQMAGAGIKYIPSNTF 258
            +H +G+PR+G  RELK A E +W G+   +DL  V ++LR   W++   +GI YIP   F
Sbjct: 5    NHTLGFPRIGLNRELKKAQEQYWSGELMIKDLLLVGSELRKKNWQKQKESGIDYIPVGDF 64

Query: 259  AYYDQVLDTTAMLGAVPDRYSWTGGEINLSTYFSMARG-NATVPAMEMTKWFDTNYHFIV 435
            A+YD VL T+ MLG +P+R++ T   I+L   F +ARG    + A EMTKWF+TNYH+IV
Sbjct: 65   AWYDHVLTTSMMLGNIPERHNNTVDSIDLDCLFRIARGCPPDISASEMTKWFNTNYHYIV 124

Query: 436  PELGPDTKFSYSSHKAINEYKEAKALGVDTVPVLVGPVSYLLLSKAAKGVEKSFXXXXXX 615
            PE   +    YS  + ++E  EA  LG    P+L+GP++YL L K  KG  + F      
Sbjct: 125  PEFYKNKVLKYSWKQILDEVDEALLLGHKVKPILLGPITYLWLGKV-KG--EYFDRLDIL 181

Query: 616  XXXXXVYKEVIAELKAAGASWIQFDEPTLVKDPESHQLAAFSAAYTELESTLSGLNVLVE 795
                 +YK V+ EL      ++Q DEP LV +       A+  AY EL    SG+  L+ 
Sbjct: 182  KDIILIYKHVLKELSNRSIDFVQIDEPVLVLELPKKWKDAYHYAYKEL----SGITKLLL 237

Query: 796  TYFADVPAESYKTLTSLSSVTAYGFDLERGTKTLELVKSGFPAGKYLFAGVVDGRYIWAD 975
            T + D    + + +  L  V     DL  G   L+   S  P+   L  GV++GR IW  
Sbjct: 238  TTYFDSIEHNIEFIRDLP-VQGIHIDLVHGKYNLKNFSSKIPSEWMLSLGVINGRNIWRS 296

Query: 976  DLAASLATLQSLEAIVGKDKLVVSTSCSLMHTAVDLVNETKLDDEIKSWLAFAAQKVVEV 1155
            DL     +++S+       K+++ +SCSL+HT +DLV E  LD E+K W +FA QK  E+
Sbjct: 297  DLLKWFKSIKSISN--HHRKILIGSSCSLLHTPIDLVAEKHLDKEVKRWFSFAVQKCEEL 354

Query: 1156 NALAKALAGQKDEXXXXXXXXXXXXXXXXXXVTNEEVQKAATALKGSDHRRATTVSARLD 1335
              L+ AL    D                   V   EV+   + +    H+R +    R  
Sbjct: 355  RLLSSAL-NDNDIDSIKEWSLPIYERSVSKRVNKIEVENRLSNVLIDKHQRLSPYKTRSI 413

Query: 1336 AQQKKLNLPVLPTTTIGSFPQTVELRRVRREYKAKKISEEEYTNAIKEEISKVVKIQEEL 1515
             Q KK N P+LPTTTIGSFPQT+ +R++RR++K   ++EEEYT  IK+ I KV+KIQEEL
Sbjct: 414  EQNKKFNFPILPTTTIGSFPQTISIRKLRRDFKLGLVTEEEYTKIIKKNIKKVIKIQEEL 473

Query: 1516 DIDVLVHGEPERNDMVEYFGEQLSGFTFTANGWVQSYGSRCVKPPIIYGDVSRPNPMTVF 1695
            DIDVLVHGE ERNDMVEYFGE L GF FT NGWVQSYGSRCVKPPII GD+SRP PMT+ 
Sbjct: 474  DIDVLVHGEAERNDMVEYFGEHLDGFAFTDNGWVQSYGSRCVKPPIIIGDISRPKPMTIE 533

Query: 1696 WSKMAQSMTARPMKGMLTGPVTILNWSFVRNDQPRFETCYQIALAIKKEVEDLEAGGIQV 1875
            WSK AQS+T +P+KGMLTGPVTIL WSF R D    +   QIALA+  EV DLE   I++
Sbjct: 534  WSKYAQSLTKKPVKGMLTGPVTILLWSFPREDVSLKKIATQIALALYDEVLDLEKEKIEI 593

Query: 1876 IQIDEAALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDTTQIHTHMCYSNFNDIIQSII 2055
            IQIDE ALREGLPLRKS    YL WAV  FR++  GV++TTQIHTHMCY  FNDI+ SI 
Sbjct: 594  IQIDEPALREGLPLRKSSWHEYLSWAVDVFRLSASGVKNTTQIHTHMCYCEFNDIMDSIA 653

Query: 2056 NMDADVITIENSRSDEKLLSVFREGVVYGAGIGPGVYDIHSPRIPSKEEIADRVNKMLAV 2235
             +DADVITIE +RSD +LL  F++   Y   +GPG YDIHS  IPS + I   +NK +  
Sbjct: 654  LLDADVITIEAARSDMELLESFKK-FKYPNEVGPGAYDIHSSNIPSVQSIISLLNKAMKY 712

Query: 2236 LDTNILWVNPDCGLKTRKYAEVKPALTNMVEAAKQIRAELAKAQ 2367
            +    +WVNPDCGLKTR + E   +L NMVEA K +R ++  ++
Sbjct: 713  IPLKRIWVNPDCGLKTRNWNETILSLKNMVEATKILREKMKDSE 756

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>Q8ZAL3:METE_YERPE 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase|
            - Yersinia pestis
          Length = 758

 Score =  645 bits (1665), Expect = 0.0
 Identities = 356/764 (46%), Positives = 461/764 (60%), Gaps = 6/764 (0%)
 Frame = +1

Query: 79   SHIVGYPRMGPKRELKFALESFWDGKSSAEDLEKVATDLRASIWKQMAGAGIKYIPSNTF 258
            +H +G+PR+G KRELK A ES+W G S+ E+L  V  +LRA  W+Q   AG+  +P   F
Sbjct: 5    NHTLGFPRVGLKRELKKAQESYWAGNSTQEELLNVGRELRARHWQQQQQAGVDLVPVGDF 64

Query: 259  AYYDQVLDTTAMLGAVPDRYSWTGGEINLSTYFSMARGNATV----PAMEMTKWFDTNYH 426
            A+YD VL T+ +LG VP+R+    G I++ T F + RG A       A EMTKWF+TNYH
Sbjct: 65   AWYDHVLTTSLLLGNVPERHQNADGSIDIDTLFRIGRGRAPTGKPAAAAEMTKWFNTNYH 124

Query: 427  FIVPELGPDTKFSYSSHKAINEYKEAKALGVDTVPVLVGPVSYLLLSKAAKGVEKSFXXX 606
            ++VPE     +F     + ++E  EA ALG    PVL+GP++YL L K  KG  + F   
Sbjct: 125  YMVPEFQQGQQFKLGWTQLLDEVDEALALGHKIKPVLLGPITYLWLGKV-KG--EQFDRL 181

Query: 607  XXXXXXXXVYKEVIAELKAAGASWIQFDEPTLVKDPESHQLAAFSAAYTELESTLSGLNV 786
                    VY++V+AEL   G  W+Q DEP LV +     L A+  AY  L+  +    +
Sbjct: 182  SLLNDILPVYQQVLAELAKRGIEWVQIDEPALVLELPQEWLDAYQPAYQALQGQVK---L 238

Query: 787  LVETYFADVPAESYKTLTSLSSVTAYGFDLERGTKTLELVKSGFPAGKYLFAGVVDGRYI 966
            L+ TYF  +   +  T+ +L  V     D+  G   L ++    P    L  GV++GR +
Sbjct: 239  LLTTYFDSI-GHNIDTIRALP-VQGLHVDVVTGHDDLAVLNKNLPKEWLLSLGVINGRNV 296

Query: 967  WADDLAASLATLQSLEAIVGKDKLVVSTSCSLMHTAVDLVNETKLDDEIKSWLAFAAQKV 1146
            W  DL++    LQ L   V    L + +SCSL+H+ +DL  ET+LD E+KSW AFA QK 
Sbjct: 297  WRADLSSWFERLQPL---VNSRPLWLGSSCSLLHSPIDLNEETRLDAEVKSWFAFALQKC 353

Query: 1147 VEVNALAKALAGQKDEXXXXXXXXXXXXXXXXXX--VTNEEVQKAATALKGSDHRRATTV 1320
             E+  L +AL    D                     V N +V++   A+   D  R    
Sbjct: 354  AELALLTQALNAPNDAKLAELAAYSAPIRARRSSSRVHNAQVEQRLAAITSQDIERQLPY 413

Query: 1321 SARLDAQQKKLNLPVLPTTTIGSFPQTVELRRVRREYKAKKISEEEYTNAIKEEISKVVK 1500
             AR + Q+K+ NLP  PTTTIGSFPQT E+R +R ++K  ++  + Y   I E I   + 
Sbjct: 414  EARAETQRKRFNLPAWPTTTIGSFPQTTEIRGLRLDFKQGRLDGKNYRTGISEHIKHAIA 473

Query: 1501 IQEELDIDVLVHGEPERNDMVEYFGEQLSGFTFTANGWVQSYGSRCVKPPIIYGDVSRPN 1680
             QE L +DVLVHGE ERNDMVEYFGE L GF FT NGWVQSYGSRCVKPP+I GD+SRP 
Sbjct: 474  EQERLGLDVLVHGEAERNDMVEYFGEHLDGFVFTQNGWVQSYGSRCVKPPVIIGDISRPE 533

Query: 1681 PMTVFWSKMAQSMTARPMKGMLTGPVTILNWSFVRNDQPRFETCYQIALAIKKEVEDLEA 1860
             +TV W+K AQS+T +P+KGMLTGPVTIL WSF R D  R     QIALA++ EVEDLE 
Sbjct: 534  AITVEWAKYAQSLTEKPVKGMLTGPVTILCWSFPREDVSRETIAKQIALALRDEVEDLEK 593

Query: 1861 GGIQVIQIDEAALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDTTQIHTHMCYSNFNDI 2040
             GI +IQIDE ALREGLPLR+++   YL WAV +F++     Q+ TQIHTHMCY  FNDI
Sbjct: 594  AGIGIIQIDEPALREGLPLRRADWQAYLQWAVDAFKLNAAVAQNDTQIHTHMCYCEFNDI 653

Query: 2041 IQSIINMDADVITIENSRSDEKLLSVFREGVVYGAGIGPGVYDIHSPRIPSKEEIADRVN 2220
            + SI  +DADVITIE SRSD +LL  F E   Y   IGPGVYDIHSP +PS E I   + 
Sbjct: 654  MDSIAALDADVITIETSRSDMELLESF-EDFAYPNEIGPGVYDIHSPNVPSVEWIEALLR 712

Query: 2221 KMLAVLDTNILWVNPDCGLKTRKYAEVKPALTNMVEAAKQIRAE 2352
            K    +    LWVNPDCGLKTR + E + AL NMV AA+++R E
Sbjct: 713  KAAQRIPAERLWVNPDCGLKTRGWPETRQALANMVLAAQRLREE 756

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>Q8X8L5:METE_ECO57 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase|
            - Escherichia coli O157:H7
          Length = 753

 Score =  645 bits (1665), Expect = 0.0
 Identities = 361/760 (47%), Positives = 459/760 (60%), Gaps = 4/760 (0%)
 Frame = +1

Query: 79   SHIVGYPRMGPKRELKFALESFWDGKSSAEDLEKVATDLRASIWKQMAGAGIKYIPSNTF 258
            +H +G+PR+G +RELK A ES+W G S+ E+L  V  +LRA  W Q   AGI  +P   F
Sbjct: 5    NHTLGFPRVGLRRELKKAQESYWAGNSTREELLAVGRELRARHWDQQKQAGIDLLPVGDF 64

Query: 259  AYYDQVLDTTAMLGAVPDRYSWTGGEINLSTYFSMARGNATV----PAMEMTKWFDTNYH 426
            A+YD VL T+ +LG VP R+    G +++ T F + RG A       A EMTKWF+TNYH
Sbjct: 65   AWYDHVLTTSLLLGNVPARHQNKDGSVDIDTLFRIGRGRAPTGEPAAAAEMTKWFNTNYH 124

Query: 427  FIVPELGPDTKFSYSSHKAINEYKEAKALGVDTVPVLVGPVSYLLLSKAAKGVEKSFXXX 606
            ++VPE     +F  +  + ++E  EA ALG    PVL+GP+++L L K  KG  + F   
Sbjct: 125  YMVPEFVKGQQFKLTWTQLLDEVDEALALGHKVKPVLLGPITWLWLGKV-KG--EQFDRL 181

Query: 607  XXXXXXXXVYKEVIAELKAAGASWIQFDEPTLVKDPESHQLAAFSAAYTELESTLSGLNV 786
                    VY++V+AEL   G  W+Q DEP LV +     L A+  AY  L+  +    +
Sbjct: 182  SLLNDILPVYQQVLAELAKRGIEWVQIDEPALVLELPQAWLDAYKPAYDALQGQVK---L 238

Query: 787  LVETYFADVPAESYKTLTSLSSVTAYGFDLERGTKTLELVKSGFPAGKYLFAGVVDGRYI 966
            L+ TYF  V   +  T+T+L  V     DL  G   +  +    P+   L AG+++GR +
Sbjct: 239  LLTTYFEGV-TPNLDTITALP-VQGLHVDLVHGKDDVVELHKRLPSDWLLSAGLINGRNV 296

Query: 967  WADDLAASLATLQSLEAIVGKDKLVVSTSCSLMHTAVDLVNETKLDDEIKSWLAFAAQKV 1146
            W  DL      ++    IVGK  L V++SCSL+H+ +DL  ET+LD E+KSW AFA QK 
Sbjct: 297  WRADLTEKYVQIKD---IVGKRDLWVASSCSLLHSPIDLSVETRLDAEVKSWFAFALQKC 353

Query: 1147 VEVNALAKALAGQKDEXXXXXXXXXXXXXXXXXXVTNEEVQKAATALKGSDHRRATTVSA 1326
             E+  L  AL    D                   V N  V+K   A+   D +RA     
Sbjct: 354  HELALLCDAL-NSGDTAALAEWSAPIQARRHSTRVHNPAVEKRLAAITAQDSQRANVYEV 412

Query: 1327 RLDAQQKKLNLPVLPTTTIGSFPQTVELRRVRREYKAKKISEEEYTNAIKEEISKVVKIQ 1506
            R +AQ+ +  LP  PTTTIGSFPQT E+R +R ++K   +    Y   I E I + +  Q
Sbjct: 413  RAEAQRARFKLPAWPTTTIGSFPQTTEIRTLRLDFKKGNLDANNYRTGIAEHIRQAIVEQ 472

Query: 1507 EELDIDVLVHGEPERNDMVEYFGEQLSGFTFTANGWVQSYGSRCVKPPIIYGDVSRPNPM 1686
            E L +DVLVHGE ERNDMVEYFGE L GF FT NGWVQSYGSRCVKPPI+ GDVSRP P+
Sbjct: 473  ERLGLDVLVHGEAERNDMVEYFGEHLDGFVFTQNGWVQSYGSRCVKPPIVIGDVSRPAPI 532

Query: 1687 TVFWSKMAQSMTARPMKGMLTGPVTILNWSFVRNDQPRFETCYQIALAIKKEVEDLEAGG 1866
            TV W+K AQSMT +P+KGMLTGPVTIL WSF R D  R     QIALA++ EV DLEA G
Sbjct: 533  TVEWAKYAQSMTDKPVKGMLTGPVTILCWSFPREDVSRETIAKQIALALRDEVADLEAAG 592

Query: 1867 IQVIQIDEAALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDTTQIHTHMCYSNFNDIIQ 2046
            I +IQIDE ALREGLPLR+S+   YL W V +FRI     +D TQIHTHMCY  FNDI+ 
Sbjct: 593  IGIIQIDEPALREGLPLRRSDWDAYLQWGVEAFRINAAVAKDDTQIHTHMCYCEFNDIMD 652

Query: 2047 SIINMDADVITIENSRSDEKLLSVFREGVVYGAGIGPGVYDIHSPRIPSKEEIADRVNKM 2226
            SI  +DADVITIE SRSD +LL  F E   Y   IGPGVYDIHSP +PS E I   + K 
Sbjct: 653  SIAALDADVITIETSRSDMELLESFEE-FDYPNEIGPGVYDIHSPNVPSVEWIEALLKKA 711

Query: 2227 LAVLDTNILWVNPDCGLKTRKYAEVKPALTNMVEAAKQIR 2346
               +    LWVNPDCGLKTR + E + AL NMV+AA+ +R
Sbjct: 712  AKRIPAERLWVNPDCGLKTRGWPETRAALANMVQAAQNLR 751

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>Q71YY6:METE_LISMF 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase|
            - Listeria monocytogenes serotype 4b (strain F2365)
          Length = 765

 Score =  642 bits (1656), Expect = 0.0
 Identities = 356/766 (46%), Positives = 473/766 (61%), Gaps = 5/766 (0%)
 Frame = +1

Query: 70   KMASHIVGYPRMGPKRELKFALESFWDGKSSAEDLEKVATDLRASIWKQMAGAGIKYIPS 249
            K  S  +GYPR+G KRE K ALE FW+G  S ++L      LR    K+    GI  IP 
Sbjct: 3    KAISSNLGYPRLGEKREWKRALEKFWNGTISEKELLAETKILRLHALKKQQDKGIDLIPV 62

Query: 250  NTFAYYDQVLDTTAMLGAVPDRYSWTGGEINLSTYFSMARGNATVPAMEMTKWFDTNYHF 429
              F++YDQVLDT+   G +P R+   GG+++L+TYF +ARG     A EMTKWF+TNYH+
Sbjct: 63   GDFSFYDQVLDTSVTFGIIPKRFQHDGGKVSLNTYFDIARGKNDAVASEMTKWFNTNYHY 122

Query: 430  IVPELGPDTKFSYSSHKAINEYKEAKA-LGVDTVPVLVGPVSYLLLSKAAKGVEKSFXXX 606
            IVPEL  D +     ++A+  Y+EAK  LG++  PVLVGP++YL L K +    KSF   
Sbjct: 123  IVPELA-DAEPKVLDNRALYYYEEAKKELGIEGKPVLVGPITYLKLGKGSDA--KSFEVL 179

Query: 607  XXXXXXXXVYKEVIAELKAAGASWIQFDEPTLVKDPESHQLAAFSAAYTELESTLSGLNV 786
                     Y E++ EL+AAGA W+Q DEP L    +  ++A F   Y   ++ +  L +
Sbjct: 180  LDKFIP--AYVEILKELEAAGAKWVQIDEPYLATSFDKKEIALFEKVYQAFQTAVPNLKI 237

Query: 787  LVETYFADVPAESYKTLTSLSSVTAYGFDL--ERGTKTLELVKSGFPAGKYLFAGVVDGR 960
             ++TYF  +  + Y+ + +L  V A G D   + G     L   GFP  KYL AGVVDGR
Sbjct: 238  ELQTYFESL--DYYEEVVNLP-VAAIGIDFVHDHGDSIKALKAHGFPEDKYLAAGVVDGR 294

Query: 961  YIWADDLAASLATLQSLEAIVGKDKLVVSTSCSLMHTAVDLVNETKLDDEIKSWLAFAAQ 1140
             +W  DL A L  L  +   V   KL+V  S SL+H  V  ++E  LD+ I   L+FA Q
Sbjct: 295  NVWRSDLDAKLELLTEIANYVADGKLIVQPSNSLLHVPVTKLSEPDLDEVILGGLSFADQ 354

Query: 1141 KVVEVNALAKALAGQKDEXXXXXXXXXXXXXXXXXXV--TNEEVQKAATALKGSDHRRAT 1314
            K+ E+  L KAL    +                       N EVQ+A   LK     R  
Sbjct: 355  KLEEITILTKALTNGAESVAAELEESRAAVTALNESSHRNNLEVQEAIANLKNVRVDREL 414

Query: 1315 TVSARLDAQQKKLNLPVLPTTTIGSFPQTVELRRVRREYKAKKISEEEYTNAIKEEISKV 1494
              + R+  Q   L LP+ PTTTIGSFPQ+ E+R+ R ++    I++ EY   I++E ++ 
Sbjct: 415  PFAERIKLQHAWLKLPLFPTTTIGSFPQSPEVRKTRADWLKGNITDAEYNAFIEKETARW 474

Query: 1495 VKIQEELDIDVLVHGEPERNDMVEYFGEQLSGFTFTANGWVQSYGSRCVKPPIIYGDVSR 1674
            +KIQE+LDIDVLVHGE ER DMVEYFG++L+GF  T  GWVQSYGSR V+PP+IYGDV+ 
Sbjct: 475  IKIQEDLDIDVLVHGEFERTDMVEYFGQKLAGFQATKFGWVQSYGSRAVRPPLIYGDVAF 534

Query: 1675 PNPMTVFWSKMAQSMTARPMKGMLTGPVTILNWSFVRNDQPRFETCYQIALAIKKEVEDL 1854
               +TV  S  AQS+T RP+KGMLT PVTI+NWSFVR+D P      Q+ LA++KEVE L
Sbjct: 535  TEEITVKESVYAQSLTKRPVKGMLTAPVTIINWSFVRDDVPESVVANQVGLALRKEVEAL 594

Query: 1855 EAGGIQVIQIDEAALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDTTQIHTHMCYSNFN 2034
            E  GI+VIQ+DE ALREGLPL+++    YLD AV+SF++T   VQ+ TQIHTHMCYS+F+
Sbjct: 595  ERNGIKVIQVDEPALREGLPLKQARWQKYLDDAVYSFKLTTASVQNDTQIHTHMCYSDFD 654

Query: 2035 DIIQSIINMDADVITIENSRSDEKLLSVFREGVVYGAGIGPGVYDIHSPRIPSKEEIADR 2214
            DII +I  +DADVI+IE SRS  +++S F E V Y   IG GVYDIHSPR+P+  EI D 
Sbjct: 655  DIIDTISALDADVISIETSRSHGEIISTFEE-VTYDKEIGLGVYDIHSPRVPTVTEIQDN 713

Query: 2215 VNKMLAVLDTNILWVNPDCGLKTRKYAEVKPALTNMVEAAKQIRAE 2352
            + + L  +D    W+NPDCGLKTRK  E   AL +M++A K++RAE
Sbjct: 714  IRRALRAIDAKQFWINPDCGLKTRKEPETIAALQDMIKATKEVRAE 759

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>Q8G651:METE_BIFLO 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase|
            - Bifidobacterium longum
          Length = 767

 Score =  642 bits (1655), Expect = 0.0
 Identities = 356/767 (46%), Positives = 470/767 (61%), Gaps = 8/767 (1%)
 Frame = +1

Query: 85   IVGYPRMGPKRELKFALESFWDGKSSAEDLEKVATDLRASIWKQMAGAGIKYIPSNTFAY 264
            + G+PR+G  RELK  +E +W G +    ++  A +LRA  WK    AGI  IPSN F+Y
Sbjct: 7    VSGFPRIGQNRELKKIIEGYWKGANDLAAVKATAAELRAKHWKLQQAAGIDLIPSNDFSY 66

Query: 265  YDQVLDTTAMLGAVPDRYSWTGGEINLSTYFSMARG----NATVPAMEMTKWFDTNYHFI 432
            YDQ+LDT  +L  +P RY+    +    T F+MARG       V A+ M KWF TNYH++
Sbjct: 67   YDQMLDTAILLNVIPQRYARLSFDNQEDTLFAMARGYQGDKGDVTALPMKKWFTTNYHYL 126

Query: 433  VPELGPDTKFSYSSHKAINEYKEAKALGVDTVPVLVGPVSYLLLSKAAKGVEKSFXXXXX 612
            VPE+    +   +S K  +E+ EAKALG+DT PV +GP ++L L++  +  E        
Sbjct: 127  VPEVESAAEIKLNSTKPFDEFNEAKALGIDTKPVFIGPYTFLKLARTPEATELELDKGLV 186

Query: 613  XXXXXXVYKEVIAELKAAGASWIQFDEPTLVKDPESHQLAAFSAAYTELESTLSGLNVLV 792
                  VY EV+A+    GA+W+Q DEP LV D E   +  F   YT++ S    + VL+
Sbjct: 187  NAVAA-VYVEVLAKFNELGAAWVQLDEPYLVLDKEPGDVELFKTLYTKILSAKGNVKVLL 245

Query: 793  ETYFADVPAESYKTLTSLSSVTAYGFDLERGTK-TLELV-KSGFPAGKYLFAGVVDGRYI 966
             TYF  + A+ Y+T+ +L      G DL  G +  LE V K G  +   +FAGV++GR I
Sbjct: 246  NTYFGHI-ADVYETV-NLLGFDGIGLDLNEGREENLEAVAKYGVASNTTIFAGVINGRNI 303

Query: 967  WADDLAASLATLQSLEAIVGKDKLVVSTSCSLMHTAVDLVNETKLDDEIKSWLAFAAQKV 1146
            W ++ A SL  + +L+ +     + VST+ SL+H       ET +  E     AFA QK+
Sbjct: 304  WRNNYATSLGLVDALKQVTAN--VAVSTASSLLHVPFSTEGETGIPAEDLKHFAFAVQKL 361

Query: 1147 VEVNALAKALAGQKDEXXXXXXXXXXXXXXXXXXVTNEE-VQKAATALKGSDHRRATTVS 1323
             E+  +A      +DE                  V  +  V +    L  +D+ R     
Sbjct: 362  DELKEVAALADATEDEKKASAALAANQALFDGTRVAADPAVAERIGKLSDADYVRQPARE 421

Query: 1324 ARLDAQQKKLNLPVLPTTTIGSFPQTVELRRVRREYKAKKISEEEYTNAIKEEISKVVKI 1503
             R   Q++ L LP+LPTTTIGSFPQT E+R  R + +  ++++E Y   IK +I  V+K 
Sbjct: 422  ERQALQREALGLPLLPTTTIGSFPQTKEIRAERAKLRKGEVTKEAYDEFIKAQIDAVIKK 481

Query: 1504 QEELDIDVLVHGEPERNDMVEYFGEQLSGFTFTANGWVQSYGSRCVKPPIIYGDVSRPNP 1683
            QEE+ +DVLVHGE ERNDMVEYFG+ L+GF FT N WVQSYG+RCVKPPI++GDVSR NP
Sbjct: 482  QEEIGLDVLVHGEFERNDMVEYFGQNLNGFLFTKNAWVQSYGTRCVKPPIVWGDVSRANP 541

Query: 1684 MTVFWSKMAQSMTARPMKGMLTGPVTILNWSFVRNDQPRFETCYQIALAIKKEVEDLEAG 1863
            +TV WS  AQS T   MKGMLTGPVTILNWS+ R D    E   Q+ALAI+ EV DLEA 
Sbjct: 542  ITVEWSAYAQSKTDHVMKGMLTGPVTILNWSWPREDITHEEQTKQLALAIRDEVLDLEAA 601

Query: 1864 GIQVIQIDEAALREGLPLRKSE-HAFYLDWAVHSFRITNCGVQDTTQIHTHMCYSNFNDI 2040
            GI+VIQIDEAALRE LPLRKS+ H  YLDWAV +FR+ +  V+ TTQIHTHMCYS FNDI
Sbjct: 602  GIKVIQIDEAALREKLPLRKSDWHVKYLDWAVPAFRLVHSAVKPTTQIHTHMCYSEFNDI 661

Query: 2041 IQSIINMDADVITIENSRSDEKLLSVFREGVVYGAGIGPGVYDIHSPRIPSKEEIADRVN 2220
            I+ I  MDADVI+ E SR D  +L    +   +    GPGVYDIHSPRIPS++EI DR+ 
Sbjct: 662  IRDIDAMDADVISFEASRGDLVVLDAIHD-AHFETEAGPGVYDIHSPRIPSEKEIEDRIY 720

Query: 2221 KMLAVLDTNILWVNPDCGLKTRKYAEVKPALTNMVEAAKQIRAELAK 2361
            ++L  +D   +W+NPDCGLKTR  AE  P+L N+V AAK +RA+L K
Sbjct: 721  EILDKMDVKKVWINPDCGLKTRGNAETWPSLENLVAAAKAVRAKLDK 767

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>Q7MZ74:METE_PHOLL 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase|
            - Photorhabdus luminescens subsp. laumondii
          Length = 758

 Score =  641 bits (1654), Expect = 0.0
 Identities = 356/763 (46%), Positives = 461/763 (60%), Gaps = 7/763 (0%)
 Frame = +1

Query: 79   SHIVGYPRMGPKRELKFALESFWDGKSSAEDLEKVATDLRASIWKQMAGAGIKYIPSNTF 258
            +H +G+PR+G KRELK A E++W GK S ++L +   +LRA  W+Q   AG+  +P   F
Sbjct: 5    NHTLGFPRIGLKRELKKAQENYWAGKISQQELLETGRELRARHWEQQKQAGVDLVPVGDF 64

Query: 259  AYYDQVLDTTAMLGAVPDRYSWTGGEINLSTYFSMARGNATV----PAMEMTKWFDTNYH 426
            A+YD VL T+ +LG VP R+    G I+L T F +ARG A       A EMTKWF+TNYH
Sbjct: 65   AWYDHVLTTSLLLGNVPPRHQNPDGTIDLDTLFRIARGRAPTGEPAAAAEMTKWFNTNYH 124

Query: 427  FIVPELGPDTKFSYSSHKAINEYKEAKALGVDTVPVLVGPVSYLLLSKAAKGVEKSFXXX 606
            +IVPE     +F  S  + + E  EA +LG    PVL+GP++YL L K    V   F   
Sbjct: 125  YIVPEFQQGQEFKLSWTQLLEEVDEALSLGHQVKPVLLGPITYLWLGKVKGQV---FDRL 181

Query: 607  XXXXXXXXVYKEVIAELKAAGASWIQFDEPTLVKDPESHQLAAFSAAYTELESTLSGLNV 786
                    VY++V+AEL   G  W+Q DEP LV +  +  L A+  AY  L+  +    +
Sbjct: 182  SLLQDILPVYQQVLAELAKRGIEWVQIDEPALVLELPAEWLTAYPIAYQALQGQVK---L 238

Query: 787  LVETYFADVPAESYKTLTSLSSVTAYGFDLERGTKTLELVKSGFPAGKYLFAGVVDGRYI 966
            L+ TYF  +   + +T+ SL  V     DL  G   +  +    P    L  GV++GR +
Sbjct: 239  LLTTYFDSI-GHNLETIKSLP-VQGLHVDLVAGQDDIAQLHESLPKEWVLSLGVINGRNV 296

Query: 967  WADDLAASLATLQSLEAIVGKDKLVVSTSCSLMHTAVDLVNETKLDDEIKSWLAFAAQKV 1146
            W  DL A     Q ++ +VG   L + +SCSL+H+ +DL +ET LD E+KSW AFA QK 
Sbjct: 297  WRADLTAKH---QLIKPLVGSRTLWIGSSCSLLHSPIDLSDETALDAEVKSWFAFALQKC 353

Query: 1147 VEVNALAKALAGQKD---EXXXXXXXXXXXXXXXXXXVTNEEVQKAATALKGSDHRRATT 1317
             E+  L  AL  Q D   +                  V N+ V +   A+   D  R   
Sbjct: 354  EELALLTAAL-NQPDGSKQAELDAYSAPIRARRESKRVNNQAVTERLAAINPQDSERNQP 412

Query: 1318 VSARLDAQQKKLNLPVLPTTTIGSFPQTVELRRVRREYKAKKISEEEYTNAIKEEISKVV 1497
               R + Q+++ NLP+ PTTTIGSFPQT E+R +R ++K  ++    Y   I E I + +
Sbjct: 413  YLQRAEIQRQRYNLPLWPTTTIGSFPQTTEIRGLRLDFKKGRVDGTSYRTNICEHIKQAI 472

Query: 1498 KIQEELDIDVLVHGEPERNDMVEYFGEQLSGFTFTANGWVQSYGSRCVKPPIIYGDVSRP 1677
              QE L +DVLVHGE ERNDMVEYFGE L GF FT NGWVQSYGSRCVKPP+I GDVSRP
Sbjct: 473  NEQERLGLDVLVHGEAERNDMVEYFGEHLDGFVFTQNGWVQSYGSRCVKPPVIIGDVSRP 532

Query: 1678 NPMTVFWSKMAQSMTARPMKGMLTGPVTILNWSFVRNDQPRFETCYQIALAIKKEVEDLE 1857
              +TV W+K AQS+T +P+KGMLTGPVTIL WSF R D  R     QIALA++ EV+DL+
Sbjct: 533  EAITVEWAKYAQSLTEKPVKGMLTGPVTILCWSFPREDVSRETIAKQIALALRDEVDDLQ 592

Query: 1858 AGGIQVIQIDEAALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDTTQIHTHMCYSNFND 2037
              GI +IQIDE ALREGLPLR+ E   YLDWAV +F++     +D TQIHTHMCY  FND
Sbjct: 593  EAGIGIIQIDEPALREGLPLRREEWQSYLDWAVEAFKLNAAIAKDDTQIHTHMCYCEFND 652

Query: 2038 IIQSIINMDADVITIENSRSDEKLLSVFREGVVYGAGIGPGVYDIHSPRIPSKEEIADRV 2217
            I+ SI  +DADVITIE SRSD +LL  F E   Y   IGPGVYDIHSP +PS E I   +
Sbjct: 653  IMPSIAALDADVITIETSRSDMELLDSF-ENFSYPNEIGPGVYDIHSPNVPSVEWIEALL 711

Query: 2218 NKMLAVLDTNILWVNPDCGLKTRKYAEVKPALTNMVEAAKQIR 2346
             K    +    LWVNPDCGLKTR + E + +L NMV+AAK++R
Sbjct: 712  RKAADRIPVERLWVNPDCGLKTRGWTETRQSLANMVQAAKRLR 754

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>Q92AX9:METE_LISIN 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase|
            - Listeria innocua
          Length = 765

 Score =  641 bits (1654), Expect = 0.0
 Identities = 355/766 (46%), Positives = 474/766 (61%), Gaps = 5/766 (0%)
 Frame = +1

Query: 70   KMASHIVGYPRMGPKRELKFALESFWDGKSSAEDLEKVATDLRASIWKQMAGAGIKYIPS 249
            K  S  +GYPR+G KRE K ALE FW+G  S E+L      LR    K+    GI  IP 
Sbjct: 3    KAISSNLGYPRLGEKREWKRALEKFWNGAISEEELLAETKALRLHALKKQQDKGIDLIPV 62

Query: 250  NTFAYYDQVLDTTAMLGAVPDRYSWTGGEINLSTYFSMARGNATVPAMEMTKWFDTNYHF 429
              F++YDQVLDT+   G +P R+   GG+++L+TYF +ARG +   A EMTKWF+TNYH+
Sbjct: 63   GDFSFYDQVLDTSVTFGIIPKRFQHDGGKVSLNTYFDIARGKSDAVASEMTKWFNTNYHY 122

Query: 430  IVPELGPDTKFSYSSHKAINEYKEAK-ALGVDTVPVLVGPVSYLLLSKAAKGVEKSFXXX 606
            IVPEL  +       ++A+  Y+EAK  LG++  PVLVGPV+YL L K +    +SF   
Sbjct: 123  IVPELA-EADPKVLDNRALYYYEEAKNELGIEGKPVLVGPVTYLKLGKGSDA--ESFEIL 179

Query: 607  XXXXXXXXVYKEVIAELKAAGASWIQFDEPTLVKDPESHQLAAFSAAYTELESTLSGLNV 786
                     Y E++ EL+ AGA+W+Q DEP L    +  ++A F   Y      +  L +
Sbjct: 180  LDKFIP--AYIEILKELETAGATWVQIDEPYLATSFDKKEIALFEKVYKAFHDAVPNLKI 237

Query: 787  LVETYFADVPAESYKTLTSLSSVTAYGFDL--ERGTKTLELVKSGFPAGKYLFAGVVDGR 960
             ++TYF  +  + Y+ + +L  V A G D   + G     L   GFP  KYL AGV+DGR
Sbjct: 238  ELQTYFESL--DYYEEVVNLP-VAAVGIDFVHDHGDSIKALKAHGFPQNKYLAAGVIDGR 294

Query: 961  YIWADDLAASLATLQSLEAIVGKDKLVVSTSCSLMHTAVDLVNETKLDDEIKSWLAFAAQ 1140
             +W  DL A LA L  +   V +DKL+V  S SL+H  V  ++E  LD+ I   L+FA Q
Sbjct: 295  NVWRSDLDAKLALLTDIAHYVAEDKLIVQPSNSLLHVPVTKLSEPDLDEVILGGLSFADQ 354

Query: 1141 KVVEVNALAKALAGQKDEXXXXXXXXXXXXXXXXXXV--TNEEVQKAATALKGSDHRRAT 1314
            K+ E+  L KAL    +                       N EVQ A   L+     R  
Sbjct: 355  KLDEIAILTKALTEGAESVAAELNEAREAVKALNESSHRNNLEVQAAIANLENVRVDREL 414

Query: 1315 TVSARLDAQQKKLNLPVLPTTTIGSFPQTVELRRVRREYKAKKISEEEYTNAIKEEISKV 1494
              + R+  Q + L LP+ PTTTIGSFPQ+ E+R+ R ++    I++ EY   I++E ++ 
Sbjct: 415  PFAERIKLQHEWLKLPLFPTTTIGSFPQSPEVRKTRADWLKGNITDAEYNAFIEKETARW 474

Query: 1495 VKIQEELDIDVLVHGEPERNDMVEYFGEQLSGFTFTANGWVQSYGSRCVKPPIIYGDVSR 1674
            +KIQE+LDIDVLVHGE ER DMVEYFG++L+GF  T  GWVQSYGSR V+PP+IYGDV+ 
Sbjct: 475  IKIQEDLDIDVLVHGEFERTDMVEYFGQKLAGFQATKFGWVQSYGSRAVRPPLIYGDVAF 534

Query: 1675 PNPMTVFWSKMAQSMTARPMKGMLTGPVTILNWSFVRNDQPRFETCYQIALAIKKEVEDL 1854
               +TV  S  AQS+T RP+KGMLT PVTI+NWSFVR+D P      Q+ LA++KEVE L
Sbjct: 535  TEEITVKESVYAQSLTKRPVKGMLTAPVTIINWSFVRDDVPESVVANQVGLALRKEVEAL 594

Query: 1855 EAGGIQVIQIDEAALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDTTQIHTHMCYSNFN 2034
            E  GI+VIQ+DE ALREGLPL+++    YLD AV+SF++T   VQ+ TQIHTHMCYS+F+
Sbjct: 595  ERNGIKVIQVDEPALREGLPLKQARWQKYLDDAVYSFKLTTASVQNDTQIHTHMCYSDFD 654

Query: 2035 DIIQSIINMDADVITIENSRSDEKLLSVFREGVVYGAGIGPGVYDIHSPRIPSKEEIADR 2214
            DII +I  +DADVI+IE SRS  +++S F E V Y   IG GVYDIHSPR+P+  EI D 
Sbjct: 655  DIIDTISALDADVISIETSRSHGEIISTFEE-VTYDKEIGLGVYDIHSPRVPTVSEIQDN 713

Query: 2215 VNKMLAVLDTNILWVNPDCGLKTRKYAEVKPALTNMVEAAKQIRAE 2352
            + + L  +D    W+NPDCGLKTRK  E   AL +M++A K++RAE
Sbjct: 714  IRRALRAIDAKQFWINPDCGLKTRKEPETIAALQDMIKATKEVRAE 759

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>Q9L6N1:METE_SALTY 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase|
            - Salmonella typhimurium
          Length = 754

 Score =  640 bits (1651), Expect = 0.0
 Identities = 360/760 (47%), Positives = 454/760 (59%), Gaps = 4/760 (0%)
 Frame = +1

Query: 79   SHIVGYPRMGPKRELKFALESFWDGKSSAEDLEKVATDLRASIWKQMAGAGIKYIPSNTF 258
            +H +G+PR+G +RELK A ES+W G ++ E L  V  +LRA  W+Q   AGI  +P   F
Sbjct: 5    THTLGFPRVGLRRELKKAQESYWAGNTTREALLAVGRELRARHWEQQKQAGIDLLPVGDF 64

Query: 259  AYYDQVLDTTAMLGAVPDRYSWTGGEINLSTYFSMARGNATV----PAMEMTKWFDTNYH 426
            A+YD VL T+ +LG VP R+    G +++ T F + RG A       A EMTKWF+TNYH
Sbjct: 65   AWYDHVLTTSLLLGNVPARHQNNDGSVDIDTLFRIGRGRAPTGEPAAAAEMTKWFNTNYH 124

Query: 427  FIVPELGPDTKFSYSSHKAINEYKEAKALGVDTVPVLVGPVSYLLLSKAAKGVEKSFXXX 606
            +IVPE     +F  +  + + E  EA ALG    PVL+GPV+YL L K  KG  + F   
Sbjct: 125  YIVPEFSKGQQFRLTWTQLLEEVDEALALGHKIKPVLLGPVTYLWLGKV-KG--EPFDRL 181

Query: 607  XXXXXXXXVYKEVIAELKAAGASWIQFDEPTLVKDPESHQLAAFSAAYTELESTLSGLNV 786
                    VY+ V+AEL   G  W+Q DEP LV +     L AF  AY  L   +    +
Sbjct: 182  TLLKDILPVYQHVLAELAKRGIEWVQIDEPALVLELPQAWLDAFKPAYDALAGQVK---L 238

Query: 787  LVETYFADVPAESYKTLTSLSSVTAYGFDLERGTKTLELVKSGFPAGKYLFAGVVDGRYI 966
            L+ TYF  V   +  T+ +L  V     DL  G   +  +    P    L AG+++GR +
Sbjct: 239  LLTTYFEGV-TPNLDTIIALP-VQGLHVDLIHGKDDVAELHQRLPVDWLLSAGLINGRNV 296

Query: 967  WADDLAASLATLQSLEAIVGKDKLVVSTSCSLMHTAVDLVNETKLDDEIKSWLAFAAQKV 1146
            W  DL    A    + AIVGK  L V++SCSL+H+ +DL  ET+LD E+KSW AFA QK 
Sbjct: 297  WRADLTEKYA---QINAIVGKRALWVASSCSLLHSPIDLSVETRLDTEVKSWFAFALQKC 353

Query: 1147 VEVNALAKALAGQKDEXXXXXXXXXXXXXXXXXXVTNEEVQKAATALKGSDHRRATTVSA 1326
             E+  L  AL    +                   V N  V+K   A+   D +R      
Sbjct: 354  GELALLRDAL-NSGETAALEEWSAPIQARRHSRRVHNAAVEKRLAAITAQDSQRENPYEV 412

Query: 1327 RLDAQQKKLNLPVLPTTTIGSFPQTVELRRVRREYKAKKISEEEYTNAIKEEISKVVKIQ 1506
            R +AQ+ +  LP  PTTTIGSFPQT E+R +R ++K   +    Y   I E I + +  Q
Sbjct: 413  RAEAQRARFKLPAWPTTTIGSFPQTTEIRGLRLDFKKGNLDANHYRTGIAEHIKQAIIEQ 472

Query: 1507 EELDIDVLVHGEPERNDMVEYFGEQLSGFTFTANGWVQSYGSRCVKPPIIYGDVSRPNPM 1686
            E L +DVLVHGE ERNDMVEYFGE L GF FT NGWVQSYGSRCVKPP++ GD+SRP P+
Sbjct: 473  ERLGLDVLVHGEAERNDMVEYFGEHLDGFVFTQNGWVQSYGSRCVKPPVVIGDISRPAPI 532

Query: 1687 TVFWSKMAQSMTARPMKGMLTGPVTILNWSFVRNDQPRFETCYQIALAIKKEVEDLEAGG 1866
            TV W+K AQS+T +P+KGMLTGPVTIL WSF R D  R     QIALA++ EV DLEA G
Sbjct: 533  TVEWAKYAQSLTDKPVKGMLTGPVTILCWSFPREDVTRETIAKQIALALRDEVADLEAAG 592

Query: 1867 IQVIQIDEAALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDTTQIHTHMCYSNFNDIIQ 2046
            I +IQIDE ALREGLPLR+S+   YL+W V +FRI     +D TQIHTHMCY  FNDI+ 
Sbjct: 593  IGIIQIDEPALREGLPLRRSDWDAYLEWGVEAFRINAAVAKDETQIHTHMCYCEFNDIMD 652

Query: 2047 SIINMDADVITIENSRSDEKLLSVFREGVVYGAGIGPGVYDIHSPRIPSKEEIADRVNKM 2226
            SI  +DADVITIE SRSD +LL  F E   Y   IGPGVYDIHSP +PS E I   + K 
Sbjct: 653  SIAALDADVITIETSRSDMELLESF-EAFDYPNEIGPGVYDIHSPNVPSVEWIEALLKKA 711

Query: 2227 LAVLDTNILWVNPDCGLKTRKYAEVKPALTNMVEAAKQIR 2346
               +    LWVNPDCGLKTR + E + AL NMV+AA  +R
Sbjct: 712  AQRIPAQRLWVNPDCGLKTRGWPETRAALANMVKAAHNLR 751

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>Q8CWK1:METE_VIBVU 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase|
            - Vibrio vulnificus
          Length = 778

 Score =  639 bits (1648), Expect = 0.0
 Identities = 361/774 (46%), Positives = 462/774 (59%), Gaps = 8/774 (1%)
 Frame = +1

Query: 79   SHIVGYPRMGPKRELKFALESFWDGKSSAEDLEKVATDLRASIWKQMAGAGIKYIPSNTF 258
            +HI+GYPR+G KRELKFA E +W G+    +L+KV  +LR   W+  A AG+ +  +  F
Sbjct: 5    THILGYPRIGEKRELKFAQEKYWRGEIDQAELKKVGAELRHKNWQTQASAGLSFAVAGDF 64

Query: 259  AYYDQVLDTTAMLGAVPDRYSWTGGEINLSTYFSMARGNAT-------VPAMEMTKWFDT 417
            A+YD VL TT +LG VP R+    G  +L T F + RG +          A +MTKWF+T
Sbjct: 65   AWYDHVLTTTLLLGHVPKRHRH--GFPDLDTLFRVGRGQSQSSCACHGAAASDMTKWFNT 122

Query: 418  NYHFIVPELGPDTKFSYSSHKAINEYKEAKALGVDTVPVLVGPVSYLLLSKAAKGVEKSF 597
            NYH+IVPE   +  F  S  +   E  EA   G +  PVL+GP+SYL L K    +E  F
Sbjct: 123  NYHYIVPEFSKEDTFEVSWPQLFEEVNEAVQAGHNVKPVLLGPLSYLYLGKE---IEDGF 179

Query: 598  XXXXXXXXXXXVYKEVIAELKAAGASWIQFDEPTLVKDPESHQLAAFSAAYTELESTLSG 777
                        Y+ ++A+L   G  W+Q DEP L  + E   L AF  AY  + S +  
Sbjct: 180  DRLTLLPRLLTAYQAILAKLAKQGVEWVQIDEPILALELEKPWLDAFKLAYQVIRSDVK- 238

Query: 778  LNVLVETYFADVPAESYKTLTSLSSVTAYGFDLERGTKTLELVKSGFPAGKYLFAGVVDG 957
              VL+ TYF  V  +S   +  LS V     DL    + L+ V +  P    L  GVV+G
Sbjct: 239  --VLLTTYFDSV-VDSLDRIVELS-VDGLHVDLSAAPEQLDAVLAKLPQNWVLSLGVVNG 294

Query: 958  RYIWADDLAASLATLQSLEAIVGKDKLVVSTSCSLMHTAVDLVNETKLDDEIKSWLAFAA 1137
            R +W  D+ A L  LQ ++A +G ++L V++SCSL+H+ VDL  E  L  E++SW AFA 
Sbjct: 295  RNVWRSDVKAQLERLQPVKAALG-ERLWVASSCSLLHSPVDLELEAGLSAEVRSWFAFAK 353

Query: 1138 QKVVEVNALAKALAGQKDEXXXXXXXXXXXXXXXXXX-VTNEEVQKAATALKGSDHRRAT 1314
            QKV EV  L KAL G                       V    VQ    A+     +R+ 
Sbjct: 354  QKVSEVVLLGKALDGDAAAIAQCEAYSQPIQARKSAAHVHKATVQSRVNAITAELAQRSV 413

Query: 1315 TVSARLDAQQKKLNLPVLPTTTIGSFPQTVELRRVRREYKAKKISEEEYTNAIKEEISKV 1494
              + R   Q + L LP+LPTTTIGSFPQT E+R  R  Y++ ++S  EY  A+K  I+  
Sbjct: 414  PYAERARHQAEVLQLPLLPTTTIGSFPQTSEIRVQRSAYRSGQLSSAEYEQALKGHIADA 473

Query: 1495 VKIQEELDIDVLVHGEPERNDMVEYFGEQLSGFTFTANGWVQSYGSRCVKPPIIYGDVSR 1674
            VK QE LD+DVLVHGE ERNDMVEYF E L+GF  T  GWVQSYGSRCVKP I+  D+ R
Sbjct: 474  VKRQEALDLDVLVHGEAERNDMVEYFAENLAGFQTTQFGWVQSYGSRCVKPAIVVADIER 533

Query: 1675 PNPMTVFWSKMAQSMTARPMKGMLTGPVTILNWSFVRNDQPRFETCYQIALAIKKEVEDL 1854
              P+TV WS  AQS+T++ MKGMLTGPVTIL W+F R D  R     Q+ALA++ EV DL
Sbjct: 534  EQPITVGWSTYAQSLTSKQMKGMLTGPVTILCWTFPREDISRKAIAQQLALALRDEVSDL 593

Query: 1855 EAGGIQVIQIDEAALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDTTQIHTHMCYSNFN 2034
            +  GI +IQIDE A+REGLPL+K +H  YLDWAV +FRI+    +  TQIHTHMCYS FN
Sbjct: 594  QDAGINIIQIDEPAIREGLPLKKRDHQNYLDWAVEAFRISAASARPETQIHTHMCYSEFN 653

Query: 2035 DIIQSIINMDADVITIENSRSDEKLLSVFREGVVYGAGIGPGVYDIHSPRIPSKEEIADR 2214
            +II+S+  +DADVITIE SRS+ +LL  F E   Y   IGPGVYDIHSP IPS+E I D 
Sbjct: 654  EIIESVAALDADVITIETSRSNMELLKAFEE-FNYPNEIGPGVYDIHSPNIPSEEWIVDL 712

Query: 2215 VNKMLAVLDTNILWVNPDCGLKTRKYAEVKPALTNMVEAAKQIRAELAKAQ*AV 2376
            V K    +    LWVNPDCGLKTR + E + AL N+V AAK++R E AK   AV
Sbjct: 713  VKKAAQKIPVERLWVNPDCGLKTRNWPETEAALANLVSAAKRLRKEFAKETTAV 766

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>Q8Z3B6:METE_SALTI 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase|
            - Salmonella typhi
          Length = 754

 Score =  639 bits (1648), Expect = 0.0
 Identities = 360/760 (47%), Positives = 453/760 (59%), Gaps = 4/760 (0%)
 Frame = +1

Query: 79   SHIVGYPRMGPKRELKFALESFWDGKSSAEDLEKVATDLRASIWKQMAGAGIKYIPSNTF 258
            +H +G+PR+G +RELK A ES+W G ++ E L  V  +LRA  W+Q   AGI  +P   F
Sbjct: 5    THTLGFPRVGLRRELKKAQESYWAGNTTREALLAVGRELRARHWEQQKQAGIDLLPVGDF 64

Query: 259  AYYDQVLDTTAMLGAVPDRYSWTGGEINLSTYFSMARGNATV----PAMEMTKWFDTNYH 426
            A+YD VL T+ +LG VP R+    G +++ T F + RG A       A EMTKWF+TNYH
Sbjct: 65   AWYDHVLTTSLLLGNVPARHQNNDGSVDIDTLFRIGRGRAPTGEPAAAAEMTKWFNTNYH 124

Query: 427  FIVPELGPDTKFSYSSHKAINEYKEAKALGVDTVPVLVGPVSYLLLSKAAKGVEKSFXXX 606
            +IVPE     +F  +  + + E  EA ALG    PVL+GPV+YL L K  KG  + F   
Sbjct: 125  YIVPEFSKGQQFRLTWTQLLEEVDEALALGHKIKPVLLGPVTYLWLGKV-KG--EPFDRL 181

Query: 607  XXXXXXXXVYKEVIAELKAAGASWIQFDEPTLVKDPESHQLAAFSAAYTELESTLSGLNV 786
                    VY+ V+AEL   G  W+Q DEP LV +     L AF  AY  L   +    +
Sbjct: 182  TLLKDILPVYQHVLAELAKRGVEWVQIDEPALVLELPQAWLDAFKPAYDALAGQVK---L 238

Query: 787  LVETYFADVPAESYKTLTSLSSVTAYGFDLERGTKTLELVKSGFPAGKYLFAGVVDGRYI 966
            L+ TYF  V   +  T+  L  V     DL  G   +  +    P    L AG+++GR +
Sbjct: 239  LLTTYFEGV-TPNLDTIIVLP-VQGLHVDLIHGKDDVVELHQRLPVDWLLSAGLINGRNV 296

Query: 967  WADDLAASLATLQSLEAIVGKDKLVVSTSCSLMHTAVDLVNETKLDDEIKSWLAFAAQKV 1146
            W  DL    A    + AIVGK  L V++SCSL+H+ +DL  ET+LD E+KSW AFA QK 
Sbjct: 297  WRADLTEKYA---QINAIVGKRALWVASSCSLLHSPIDLSVETRLDTEVKSWFAFALQKC 353

Query: 1147 VEVNALAKALAGQKDEXXXXXXXXXXXXXXXXXXVTNEEVQKAATALKGSDHRRATTVSA 1326
             E+  L  AL    +                   V N  V+K   A+   D +R      
Sbjct: 354  GELALLRDAL-NSGETAALEEWSVPIQARRHSHRVHNAAVEKRLAAITAQDSQRENPYEV 412

Query: 1327 RLDAQQKKLNLPVLPTTTIGSFPQTVELRRVRREYKAKKISEEEYTNAIKEEISKVVKIQ 1506
            R +AQ+ +  LP  PTTTIGSFPQT E+R +R ++K   +    Y   I E I + +  Q
Sbjct: 413  RAEAQRARFKLPAWPTTTIGSFPQTTEIRGLRLDFKKGNLDANNYRTGIAEHIKQAIIEQ 472

Query: 1507 EELDIDVLVHGEPERNDMVEYFGEQLSGFTFTANGWVQSYGSRCVKPPIIYGDVSRPNPM 1686
            E L +DVLVHGE ERNDMVEYFGE L GF FT NGWVQSYGSRCVKPP++ GD+SRP P+
Sbjct: 473  ERLGLDVLVHGEAERNDMVEYFGEHLDGFVFTQNGWVQSYGSRCVKPPVVIGDISRPAPI 532

Query: 1687 TVFWSKMAQSMTARPMKGMLTGPVTILNWSFVRNDQPRFETCYQIALAIKKEVEDLEAGG 1866
            TV W+K AQS+T +P+KGMLTGPVTIL WSF R D  R     QIALA++ EV DLEA G
Sbjct: 533  TVEWAKYAQSLTDKPVKGMLTGPVTILCWSFPREDVTRETIAKQIALALRDEVADLEAAG 592

Query: 1867 IQVIQIDEAALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDTTQIHTHMCYSNFNDIIQ 2046
            I +IQIDE ALREGLPLR+S+   YL+W V +FRI     +D TQIHTHMCY  FNDI+ 
Sbjct: 593  IGIIQIDEPALREGLPLRRSDWDAYLEWGVEAFRINAAVAKDETQIHTHMCYCEFNDIMD 652

Query: 2047 SIINMDADVITIENSRSDEKLLSVFREGVVYGAGIGPGVYDIHSPRIPSKEEIADRVNKM 2226
            SI  +DADVITIE SRSD +LL  F E   Y   IGPGVYDIHSP +PS E I   + K 
Sbjct: 653  SIAALDADVITIETSRSDMELLESF-EAFDYPNEIGPGVYDIHSPNVPSVEWIEALLKKA 711

Query: 2227 LAVLDTNILWVNPDCGLKTRKYAEVKPALTNMVEAAKQIR 2346
               +    LWVNPDCGLKTR + E + AL NMV+AA  +R
Sbjct: 712  AQRIPAQRLWVNPDCGLKTRGWPETRAALANMVKAAHNLR 751

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>Q7MJM6:METE_VIBVY 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase|
            - Vibrio vulnificus (strain YJ016)
          Length = 778

 Score =  637 bits (1644), Expect = 0.0
 Identities = 360/774 (46%), Positives = 461/774 (59%), Gaps = 8/774 (1%)
 Frame = +1

Query: 79   SHIVGYPRMGPKRELKFALESFWDGKSSAEDLEKVATDLRASIWKQMAGAGIKYIPSNTF 258
            +HI+GYPR+G KRELKFA E +W G+    +L+KV  +LR   W+  A AG+ +  +  F
Sbjct: 5    THILGYPRIGEKRELKFAQEKYWRGEIDQAELKKVGAELRYKNWQTQASAGLSFAVAGDF 64

Query: 259  AYYDQVLDTTAMLGAVPDRYSWTGGEINLSTYFSMARGNAT-------VPAMEMTKWFDT 417
            A+YD VL TT +LG VP R+    G  +L T F + RG +          A +MTKWF+T
Sbjct: 65   AWYDHVLTTTLLLGHVPKRHRH--GFPDLDTLFRVGRGQSQSSCACHGAAASDMTKWFNT 122

Query: 418  NYHFIVPELGPDTKFSYSSHKAINEYKEAKALGVDTVPVLVGPVSYLLLSKAAKGVEKSF 597
            NYH+IVPE   +  F  S  +   E  EA   G    PVL+GP+SYL L K    +E  F
Sbjct: 123  NYHYIVPEFSKEDTFEVSWPQLFEEVNEAVQAGHKVKPVLLGPLSYLYLGKE---IEDGF 179

Query: 598  XXXXXXXXXXXVYKEVIAELKAAGASWIQFDEPTLVKDPESHQLAAFSAAYTELESTLSG 777
                        Y+ ++A+L   G  W+Q DEP L  + E   L AF  AY  + S +  
Sbjct: 180  DRLTLLPRLLTAYQAILAKLAKQGVEWVQIDEPILALELEKPWLDAFKLAYQVIRSDVK- 238

Query: 778  LNVLVETYFADVPAESYKTLTSLSSVTAYGFDLERGTKTLELVKSGFPAGKYLFAGVVDG 957
              VL+ TYF  V  +S   +  LS V     DL    + L+ V +  P    L  GVV+G
Sbjct: 239  --VLLTTYFDSV-VDSLDRIVELS-VDGLHVDLSAAPEQLDAVLAKLPQNWVLSLGVVNG 294

Query: 958  RYIWADDLAASLATLQSLEAIVGKDKLVVSTSCSLMHTAVDLVNETKLDDEIKSWLAFAA 1137
            R +W  D+ A L  LQ ++A +G ++L V++SCSL+H+ VDL  E  L  E++SW AFA 
Sbjct: 295  RNVWRSDVKAQLERLQPVKAALG-ERLWVASSCSLLHSPVDLELEAGLSAEVRSWFAFAK 353

Query: 1138 QKVVEVNALAKALAGQKDEXXXXXXXXXXXXXXXXXX-VTNEEVQKAATALKGSDHRRAT 1314
            QKV EV  L KAL G                       V    VQ    A+     +R+ 
Sbjct: 354  QKVSEVVLLGKALDGDAASIAQCEAYSQPIQARKSAAHVHKATVQSRVNAITAELAQRSV 413

Query: 1315 TVSARLDAQQKKLNLPVLPTTTIGSFPQTVELRRVRREYKAKKISEEEYTNAIKEEISKV 1494
              + R   Q + L LP+LPTTTIGSFPQT E+R  R  Y++ ++S  EY  A+K  I+  
Sbjct: 414  PYAERARHQAEVLQLPLLPTTTIGSFPQTSEIRVQRSAYRSGQLSSAEYEQALKGHIADA 473

Query: 1495 VKIQEELDIDVLVHGEPERNDMVEYFGEQLSGFTFTANGWVQSYGSRCVKPPIIYGDVSR 1674
            VK QE LD+DVLVHGE ERNDMVEYF E L+GF  T  GWVQSYGSRCVKP I+  D+ R
Sbjct: 474  VKRQEALDLDVLVHGEAERNDMVEYFAEHLAGFQTTQFGWVQSYGSRCVKPAIVVADIER 533

Query: 1675 PNPMTVFWSKMAQSMTARPMKGMLTGPVTILNWSFVRNDQPRFETCYQIALAIKKEVEDL 1854
              P+TV WS  AQS+T++ MKGMLTGPVTIL W+F R D  R     Q+ALA++ EV DL
Sbjct: 534  EQPITVGWSTYAQSLTSKQMKGMLTGPVTILCWTFPREDISRKAIAQQLALALRDEVSDL 593

Query: 1855 EAGGIQVIQIDEAALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDTTQIHTHMCYSNFN 2034
            +  GI +IQIDE A+REGLPL+K +H  YLDWA+ +FRI+    +  TQIHTHMCYS FN
Sbjct: 594  QDAGINIIQIDEPAIREGLPLKKRDHQNYLDWALEAFRISAASARPETQIHTHMCYSEFN 653

Query: 2035 DIIQSIINMDADVITIENSRSDEKLLSVFREGVVYGAGIGPGVYDIHSPRIPSKEEIADR 2214
            +II+S+  +DADVITIE SRS+ +LL  F E   Y   IGPGVYDIHSP IPS+E I D 
Sbjct: 654  EIIESVAALDADVITIETSRSNMELLKAFEE-FNYPNEIGPGVYDIHSPNIPSEEWIVDL 712

Query: 2215 VNKMLAVLDTNILWVNPDCGLKTRKYAEVKPALTNMVEAAKQIRAELAKAQ*AV 2376
            V K    +    LWVNPDCGLKTR + E + AL N+V AAK++R E AK   AV
Sbjct: 713  VKKAAQKIPVERLWVNPDCGLKTRNWPETEAALANLVSAAKRLRKEFAKETTAV 766

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>Q8Y6K3:METE_LISMO 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase|
            - Listeria monocytogenes
          Length = 765

 Score =  634 bits (1634), Expect = 0.0
 Identities = 352/766 (45%), Positives = 469/766 (61%), Gaps = 5/766 (0%)
 Frame = +1

Query: 70   KMASHIVGYPRMGPKRELKFALESFWDGKSSAEDLEKVATDLRASIWKQMAGAGIKYIPS 249
            K  S  +GYPR+G KRE K ALE FW+G  S E+L      LR    K+    GI  IP 
Sbjct: 3    KAISSNLGYPRLGEKREWKRALEKFWNGAISEEELLAETKALRLHALKKQQEKGIDLIPV 62

Query: 250  NTFAYYDQVLDTTAMLGAVPDRYSWTGGEINLSTYFSMARGNATVPAMEMTKWFDTNYHF 429
              F++YDQVLDT+   G +P R+   GG+++L+TYF +ARG +   A EMTKWF+TNYH+
Sbjct: 63   GDFSFYDQVLDTSVTFGIIPKRFQHDGGKVSLNTYFDIARGKSDAVASEMTKWFNTNYHY 122

Query: 430  IVPELGPDTKFSYSSHKAINEYKEAKA-LGVDTVPVLVGPVSYLLLSKAAKGVEKSFXXX 606
            IVPEL  D       ++A+  Y+EAK  LG++  PVLVGPV+YL L K       +    
Sbjct: 123  IVPELA-DADPKVLDNRALYYYEEAKKELGIEGKPVLVGPVTYLKLGKG----NDAENFE 177

Query: 607  XXXXXXXXVYKEVIAELKAAGASWIQFDEPTLVKDPESHQLAAFSAAYTELESTLSGLNV 786
                     Y E++ EL+ AGA W+Q DEP L    +  ++  F   Y   ++ +  L +
Sbjct: 178  ALLDKFIPAYVEILKELERAGAKWVQIDEPYLATSFDKSEIKLFEKVYQAFQTAVPNLKI 237

Query: 787  LVETYFADVPAESYKTLTSLSSVTAYGFDL--ERGTKTLELVKSGFPAGKYLFAGVVDGR 960
             ++TYF  +  + Y+ + +L  V A G D   + G     L   GFP  KYL AGV+DGR
Sbjct: 238  ELQTYFESL--DYYEEVVNLP-VAAIGIDFVHDHGDSLEALKAHGFPEDKYLAAGVIDGR 294

Query: 961  YIWADDLAASLATLQSLEAIVGKDKLVVSTSCSLMHTAVDLVNETKLDDEIKSWLAFAAQ 1140
             +W  DL A L+ L  +   V   KL+V  S SL+H  V  ++E  LD+ I   L+FA Q
Sbjct: 295  NVWRSDLDAKLSLLTEIADYVTDGKLIVQPSNSLLHVPVTKLSEPDLDEVILGGLSFADQ 354

Query: 1141 KVVEVNALAKALAGQKDEXXXXXXXXXXXXXXXXXXV--TNEEVQKAATALKGSDHRRAT 1314
            K+ E+  L KAL    +                       N EVQ+A   L      R  
Sbjct: 355  KLDEIAILTKALTDGAESVTAELEDARAAVTALNESSHRNNLEVQEAIANLGNVRVDREL 414

Query: 1315 TVSARLDAQQKKLNLPVLPTTTIGSFPQTVELRRVRREYKAKKISEEEYTNAIKEEISKV 1494
              + R+  Q   LNLP+ PTTTIGSFPQ+ E+R+ R ++    I++ EY   I++E ++ 
Sbjct: 415  PFAERIKLQHAWLNLPLFPTTTIGSFPQSPEVRKTRADWLKGNITDAEYNAFIEKETARW 474

Query: 1495 VKIQEELDIDVLVHGEPERNDMVEYFGEQLSGFTFTANGWVQSYGSRCVKPPIIYGDVSR 1674
            +KIQEELDIDVLVHGE ER DMVEYFG++L+GF  T  GWVQSYGSR V+PP+IYGDV+ 
Sbjct: 475  IKIQEELDIDVLVHGEFERTDMVEYFGQKLAGFQATKFGWVQSYGSRAVRPPLIYGDVAF 534

Query: 1675 PNPMTVFWSKMAQSMTARPMKGMLTGPVTILNWSFVRNDQPRFETCYQIALAIKKEVEDL 1854
               +TV  S  AQS+T RP+KGMLT PVTI+NWSFVR+D P      Q+ LA++KEVE L
Sbjct: 535  TEEITVKESVYAQSLTKRPVKGMLTAPVTIINWSFVRDDVPESVVANQVGLALRKEVEAL 594

Query: 1855 EAGGIQVIQIDEAALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDTTQIHTHMCYSNFN 2034
            E  GI+VIQ+DE ALREGLPL+++    YL+ AV+SF++T   VQ+ TQIHTHMCYS+F+
Sbjct: 595  ERNGIKVIQVDEPALREGLPLKQARWEKYLNDAVYSFKLTTASVQNDTQIHTHMCYSDFD 654

Query: 2035 DIIQSIINMDADVITIENSRSDEKLLSVFREGVVYGAGIGPGVYDIHSPRIPSKEEIADR 2214
            DII +I  +DADVI+IE SRS  +++S F E V Y   IG GVYDIHSPR+P+  EI D 
Sbjct: 655  DIIDTISALDADVISIETSRSHGEIISTFEE-VTYDKEIGLGVYDIHSPRVPTVTEIQDN 713

Query: 2215 VNKMLAVLDTNILWVNPDCGLKTRKYAEVKPALTNMVEAAKQIRAE 2352
            + + L  +D    W+NPDCGLKTRK  E   AL +M++A K++RAE
Sbjct: 714  IRRALRAIDAKQFWINPDCGLKTRKEPETIAALQDMIKATKEVRAE 759

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>Q9UT19:METE_SCHPO Probable 5-methyltetrahydropteroyltriglutamate--homocysteine|
            methyltransferase - Schizosaccharomyces pombe (Fission
            yeast)
          Length = 764

 Score =  633 bits (1632), Expect = e-180
 Identities = 350/773 (45%), Positives = 468/773 (60%), Gaps = 13/773 (1%)
 Frame = +1

Query: 79   SHIVGYPRMGPKRELKFALESFWDGKSSAEDLEKVATDLRASIWKQMAGAGIKYIPSNTF 258
            S ++G+PR+G  RELK A E++W GK+SAE+L   A  LR   WK     G+  IPSN F
Sbjct: 4    SAVLGFPRIGKNRELKKATEAYWSGKTSAEELLATAKQLRLEHWKLQKAQGVDIIPSNDF 63

Query: 259  AYYDQVLDTTAMLGAVPDRYSWTGGEINLSTYFSMARGN----------ATVPAMEMTKW 408
            + YDQ++D +     +P RY  +G   +L TYF+M RG             VPA EM KW
Sbjct: 64   SLYDQIMDHSFSFNVIPPRYRLSGLS-SLDTYFAMGRGMQRAATADKAAVDVPAGEMVKW 122

Query: 409  FDTNYHFIVPELGPDTKFSYSSHKAINEYKEAKALGVDTVPVLVGPVSYLLLSKAAKGVE 588
            FD+NYHF+ PE+  +T F  SS KA++E+ EAK  G+ T PVLVGPV+YL ++KAAKG  
Sbjct: 123  FDSNYHFLRPEVSEETDFKLSSTKALDEFLEAKEAGIITRPVLVGPVTYLFIAKAAKG-- 180

Query: 589  KSFXXXXXXXXXXXVYKEVIAELKAAGASWIQFDEPTLVKDPESHQLAAFSAAYTELEST 768
             S            VY E+I +L  AGA +IQ DEP L  D     LA++  AY     T
Sbjct: 181  SSIKPIELLPKLLPVYVELIKKLTEAGAEYIQIDEPILTLDLPQEILASYKEAY----ET 236

Query: 769  LSGLNVLV-ETYFADVPAESYKTLTSLSSVTAYGFDLERGTKTLELVKSGFPAGKYLFAG 945
            L  +  L+  TYF  + + +   L  L  +     D+ R  + L+   +     + +  G
Sbjct: 237  LGKIGKLILTTYFGSLQSNA-DVLKGLP-IAGVHVDVVRAPENLDRALAVLGENQIISVG 294

Query: 946  VVDGRYIWADDLAASLATLQSLEAIVGKDKLVVSTSCSLMHTAVDLVNETKLDDEIKSWL 1125
            VV GR IW  D   + A ++   + VG +++ V++S S++H    L  E +++ EIK W 
Sbjct: 295  VVSGRNIWKTDFQKATAIIEKAISAVGSERVQVASSSSILHIPHSLSGEDQINPEIKRWF 354

Query: 1126 AFAAQKVVEVNALAKALA-GQKDEXXXXXXXXXXXXXXXXXXVTN-EEVQKAATALKGSD 1299
            AFA +K  E+  L KA   G                      +TN E V++  + +    
Sbjct: 355  AFAVEKCAELAILTKAANDGPASVRAELEANAADCKARAESPITNVEAVRERQSKVTPQM 414

Query: 1300 HRRATTVSARLDAQQKKLNLPVLPTTTIGSFPQTVELRRVRREYKAKKISEEEYTNAIKE 1479
            H R +    R   QQ  L LP+ PTTTIGSFPQT E+R  R  +    IS+EEY   I++
Sbjct: 415  HERKSPFETRYAKQQASLKLPLFPTTTIGSFPQTKEIRVTRNRFAKGLISQEEYDAFIRK 474

Query: 1480 EISKVVKIQEELDIDVLVHGEPERNDMVEYFGEQLSGFTFTANGWVQSYGSRCVKPPIIY 1659
            EIS VVK QEE+ +DVLVHGEPERNDMV+YFGE++ GF FT NGWVQSYGSRCV+PPII 
Sbjct: 475  EISDVVKFQEEVGLDVLVHGEPERNDMVQYFGERMEGFVFTVNGWVQSYGSRCVRPPIIV 534

Query: 1660 GDVSRPNPMTVFWSKMAQSMTARPMKGMLTGPVTILNWSFVRNDQPRFETCYQIALAIKK 1839
            GDV RP PMTV  S+ AQS+T++PMKGMLT P+TIL WSF R+D        QIAL ++ 
Sbjct: 535  GDVYRPAPMTVKESQYAQSITSKPMKGMLTAPITILRWSFPRDDVHDSVQAQQIALGLRD 594

Query: 1840 EVEDLEAGGIQVIQIDEAALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDTTQIHTHMC 2019
            EV DLE  GI+VIQ DE ALREGLPLR++E   YL WA+ +FR+    VQD TQIH+H C
Sbjct: 595  EVLDLEKAGIKVIQCDEPALREGLPLRRAEWDEYLKWAIDAFRLATAAVQDDTQIHSHFC 654

Query: 2020 YSNFNDIIQSIINMDADVITIENSRSDEKLLSVFREGVVYGAGIGPGVYDIHSPRIPSKE 2199
            YS+FNDI  +I  +DADV++IENS+SD KLL+V      Y + IGPG++DIHSPR+P   
Sbjct: 655  YSDFNDIFDAIQRLDADVVSIENSKSDMKLLNVLSR---YTSCIGPGLFDIHSPRVPPVS 711

Query: 2200 EIADRVNKMLAVLDTNILWVNPDCGLKTRKYAEVKPALTNMVEAAKQIRAELA 2358
            E  +R++ ++  +  + LW+NPDCGLKTR + E    L NM+ AA++ R + A
Sbjct: 712  EFKERIDAIVKHVPKDHLWLNPDCGLKTRGWPETTADLKNMIAAAREAREQYA 764

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>Q8EIM0:METE_SHEON 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase|
            - Shewanella oneidensis
          Length = 760

 Score =  632 bits (1631), Expect = e-180
 Identities = 349/768 (45%), Positives = 472/768 (61%), Gaps = 7/768 (0%)
 Frame = +1

Query: 73   MASHIVGYPRMGPKRELKFALESFWDGKSSAEDLEKVATDLRASIWKQMAGAGIKYIPSN 252
            M  + +G+PR+G +RELKFALE +W G+S+  +L +VA +LR + W+    AGI+ +P  
Sbjct: 1    MQLNSLGFPRIGRRRELKFALEKYWRGESTQAELHEVARELRRTHWQWQVAAGIEQVPVG 60

Query: 253  TFAYYDQVLDTTAMLGAVPDRYSWTGGEINLSTYFSMARGNATV----PAMEMTKWFDTN 420
             FA+YDQVL  +A L A+PDR+   G  I+L T F +ARG A      PA EMTK+F+TN
Sbjct: 61   DFAFYDQVLTLSATLNAIPDRHRGEGA-IDLDTLFRVARGRAPTGTDAPASEMTKYFNTN 119

Query: 421  YHFIVPELGPDTKFSYSSHKAINEYKEAKALGVDTVPVLVGPVSYLLLSKAAKGVEKSFX 600
            YH++VPEL  D  FS +  +  +E  EA+ALG    PVL+GPVSYL L   AK V + F 
Sbjct: 120  YHYLVPELKQDQVFSIAYEQFFDEVAEAQALGYKAKPVLLGPVSYLYL---AKTVGQDFD 176

Query: 601  XXXXXXXXXXVYKEVIAELKAAGASWIQFDEPTLVKDPESHQLAAFSAAYTELESTLSGL 780
                       Y E++A   A G +W+Q +EP L  +      AA S +Y  L++  + +
Sbjct: 177  KLSLLPNLLKAYAEILARFAAQGVTWVQLEEPILALELTHEWQAAISESYQALKT--AQV 234

Query: 781  NVLVETYFADVPAESYKTLTSLSSVTAYGFDLERGTKTLELVKSGFPAGKYLFAGVVDGR 960
             +L+ +Y+  +    ++ L S   V     DL    + L L  +     + L  GVV+GR
Sbjct: 235  KILLTSYYGSI--SHHQALVSALPVAGLHLDLVTAPEQLALFANALRPDQILSVGVVNGR 292

Query: 961  YIWADDLAASLATLQSLEA-IVGKD--KLVVSTSCSLMHTAVDLVNETKLDDEIKSWLAF 1131
             +WA ++   +  + S+   +  +D  +L + TSCSL+H+ VDL  ET L   ++  LAF
Sbjct: 293  NVWAAEVDLIVERIGSVARDLCSQDGSRLWIGTSCSLLHSPVDLEVETTLAPTLRQQLAF 352

Query: 1132 AAQKVVEVNALAKALAGQKDEXXXXXXXXXXXXXXXXXXVTNEEVQKAATALKGSDHRRA 1311
            A QK++E+  + + L   +                      + +V     AL  +D+ R 
Sbjct: 353  AKQKLLELANVRQLLQAPESVAAKEIVNTCLARREAKAQAADAKVIARVAALTPADYERV 412

Query: 1312 TTVSARLDAQQKKLNLPVLPTTTIGSFPQTVELRRVRREYKAKKISEEEYTNAIKEEISK 1491
            +  + R   QQ+K  LP+LPTTTIGSFPQT  +R +R  ++  ++S+ +YT  +++    
Sbjct: 413  SEFTERQAVQQRKYRLPLLPTTTIGSFPQTPAIRGLRSRWRKGELSDAQYTEQLQQVTRD 472

Query: 1492 VVKIQEELDIDVLVHGEPERNDMVEYFGEQLSGFTFTANGWVQSYGSRCVKPPIIYGDVS 1671
             +  Q +L IDVLVHGE ERNDMVEYFGEQL G  FT NGWVQSYGSRCVKPP+IYGDVS
Sbjct: 473  TIDRQLKLGIDVLVHGEAERNDMVEYFGEQLEGVGFTKNGWVQSYGSRCVKPPLIYGDVS 532

Query: 1672 RPNPMTVFWSKMAQSMTARPMKGMLTGPVTILNWSFVRNDQPRFETCYQIALAIKKEVED 1851
            RP  MTV W+  AQS+T +P+KGMLTGPVTIL+WSF R D  R     Q+ALAI+ EV D
Sbjct: 533  RPKAMTVDWAVFAQSLTDKPVKGMLTGPVTILHWSFAREDISRDTIATQLALAIRDEVVD 592

Query: 1852 LEAGGIQVIQIDEAALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDTTQIHTHMCYSNF 2031
            L+  GI +IQIDE A REGLPL++SE   YLDWAV++F+++  GV D TQIHTHMCYS F
Sbjct: 593  LQHAGIGIIQIDEPAFREGLPLKQSEWQAYLDWAVNAFKLSAAGVVDETQIHTHMCYSEF 652

Query: 2032 NDIIQSIINMDADVITIENSRSDEKLLSVFREGVVYGAGIGPGVYDIHSPRIPSKEEIAD 2211
            ND I +I  MDADVITIE SRS  +LL+ F E   Y   IGPGVYDIHSP  PS E +  
Sbjct: 653  NDTIAAIAAMDADVITIETSRSRMELLNAF-EDFEYPNEIGPGVYDIHSPNTPSVEAMVH 711

Query: 2212 RVNKMLAVLDTNILWVNPDCGLKTRKYAEVKPALTNMVEAAKQIRAEL 2355
             + K    +    LWVNPDCGLKTR + EV+PAL NMV+A +++R  L
Sbjct: 712  LIEKAAQKVPVRQLWVNPDCGLKTRTWDEVEPALKNMVDATRELRRRL 759

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>Q9KRD8:METE_VIBCH 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase|
            - Vibrio cholerae
          Length = 761

 Score =  630 bits (1626), Expect = e-180
 Identities = 353/769 (45%), Positives = 460/769 (59%), Gaps = 11/769 (1%)
 Frame = +1

Query: 79   SHIVGYPRMGPKRELKFALESFWDGKSSAEDLEKVATDLRASIWKQMAGAGIKYIPSNTF 258
            +HI+GYPR+G KRELKFALE +W G+     L++V + +R   W     AG+ ++ +  F
Sbjct: 4    THILGYPRIGEKRELKFALEKYWRGEIDQAALKQVGSQIRQKNWALQKEAGLDFVTAGDF 63

Query: 259  AYYDQVLDTTAMLGAVPDRYSWTGGEINLSTYFSMARGNAT--------VPAMEMTKWFD 414
            A+YD VL TT +LG VP R+S   G  +L T F + RG +           A +MTKWF+
Sbjct: 64   AWYDHVLTTTLLLGHVPKRHSH--GFPDLDTLFRVGRGQSQNACGCGTGSAASDMTKWFN 121

Query: 415  TNYHFIVPELGPDTKFSYSSHKAINEYKEAKALGVDTVPVLVGPVSYLLLSKAAKGVEKS 594
            TNYH+IVPE   +  F+ S  +   E  EA   G D  PVL+GP+SYL L K    VE+ 
Sbjct: 122  TNYHYIVPEFSSNDTFNVSWPQLFEEVNEALQAGHDVKPVLLGPISYLYLGKE---VEEG 178

Query: 595  FXXXXXXXXXXXVYKEVIAELKAAGASWIQFDEPTLVKDPESHQLAAFSAAYTELESTLS 774
            F            Y+ ++++L   G  W+Q DEP L  + E     AF  AY  +   + 
Sbjct: 179  FDRLTLLPRLLTAYQAILSKLAKQGVQWVQIDEPILALELEPRWQEAFKLAYQVIRGDVK 238

Query: 775  GLNVLVETYFADVPAESYKTLTSLSSVTAYGF--DLERGTKTLELVKSGFPAGKYLFAGV 948
               +L+ TYF  V      TL  +  +   G   D+      LE + +  P+   L AGV
Sbjct: 239  ---LLLTTYFDSV----LDTLDKIVELPVDGLHVDISAAPAQLETIVNRLPSDWVLSAGV 291

Query: 949  VDGRYIWADDLAASLATLQSLEAIVGKDKLVVSTSCSLMHTAVDLVNETKLDDEIKSWLA 1128
            ++GR +W  DL+A LA LQ ++ ++G ++L V++SCSL+H+ VDL  E  L  E +SW A
Sbjct: 292  INGRNVWRADLSAILARLQPVKTLLG-ERLWVASSCSLLHSPVDLDLEGDLSAETRSWFA 350

Query: 1129 FAAQKVVEVNALAKALAGQKDEXXXXXXXXXXXXXXXXXXVTNE-EVQKAATALKGSDHR 1305
            FA QKV EV  L +AL G                      + N+  VQ     +  +   
Sbjct: 351  FAKQKVTEVALLGRALEGDAAAILACDTYSQPIVARKSSHIVNKASVQTRINNITAALAE 410

Query: 1306 RATTVSARLDAQQKKLNLPVLPTTTIGSFPQTVELRRVRREYKAKKISEEEYTNAIKEEI 1485
            R+     R   Q + L LP LPTTTIGSFPQT E+R  R  Y+  K+SE+EY  A+K  I
Sbjct: 411  RSAPYIERAHHQAEVLGLPFLPTTTIGSFPQTGEIRTERSAYRQGKLSEQEYVQALKGHI 470

Query: 1486 SKVVKIQEELDIDVLVHGEPERNDMVEYFGEQLSGFTFTANGWVQSYGSRCVKPPIIYGD 1665
            +  VK QE L +DVLVHGE ERNDMVEYF E L+GF  T  GWVQSYGSRCVKP I+  D
Sbjct: 471  ADAVKRQEALGLDVLVHGEAERNDMVEYFAENLAGFQTTQFGWVQSYGSRCVKPAIVVAD 530

Query: 1666 VSRPNPMTVFWSKMAQSMTARPMKGMLTGPVTILNWSFVRNDQPRFETCYQIALAIKKEV 1845
            + R  P+TV WS  AQS+T++ MKGMLTGPVTIL W+F R D  R E   Q+ALA++ EV
Sbjct: 531  IEREKPITVEWSTYAQSLTSKQMKGMLTGPVTILCWTFPREDISRQEIAQQLALALRDEV 590

Query: 1846 EDLEAGGIQVIQIDEAALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDTTQIHTHMCYS 2025
             DL+  GI +IQIDE A+REGLPL+K +H  YLDWAV +F+I+    +  TQIHTHMCYS
Sbjct: 591  ADLQDAGINIIQIDEPAIREGLPLKKRDHQTYLDWAVQAFKISAGSARPETQIHTHMCYS 650

Query: 2026 NFNDIIQSIINMDADVITIENSRSDEKLLSVFREGVVYGAGIGPGVYDIHSPRIPSKEEI 2205
             FN+II+S+  +DADVITIE SRS+ +LL  F E   Y   IGPGVYDIHSP IP++  I
Sbjct: 651  EFNEIIESVAALDADVITIETSRSNMELLKAFEE-FNYPNEIGPGVYDIHSPNIPAQAWI 709

Query: 2206 ADRVNKMLAVLDTNILWVNPDCGLKTRKYAEVKPALTNMVEAAKQIRAE 2352
             D + K    +    LWVNPDCGLKTR + EV+ ALTNMV AAK +RAE
Sbjct: 710  EDLLRKAAEKIPAQRLWVNPDCGLKTRNWPEVEAALTNMVNAAKALRAE 758

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>Q8KA71:METE_BUCAP 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase|
            - Buchnera aphidicola subsp. Schizaphis graminum
          Length = 757

 Score =  628 bits (1619), Expect = e-179
 Identities = 354/765 (46%), Positives = 468/765 (61%), Gaps = 4/765 (0%)
 Frame = +1

Query: 79   SHIVGYPRMGPKRELKFALESFWDGKSSAEDLEKVATDLRASIWKQMAGAGIKYIPSNTF 258
            +H +G+PR+G  RELK A E +W G    ED   V + LR   WK+   AGI YIP   F
Sbjct: 5    NHTLGFPRIGLNRELKKAQEDYWSGNLLYEDFLCVGSQLRRENWKKQKDAGIDYIPVGDF 64

Query: 259  AYYDQVLDTTAMLGAVPDRY-SWTGGEINLSTYFSMARG-NATVPAMEMTKWFDTNYHFI 432
            A+YD VL T+ MLG +P+R+ +    +I+L   F +ARG +  V A EMTKWF+TNYH+I
Sbjct: 65   AWYDHVLSTSMMLGNIPERHLNVNDNKIDLDCLFRIARGCSPDVAASEMTKWFNTNYHYI 124

Query: 433  VPELGPDTKFSYSSHKAINEYKEAKALGVDTVPVLVGPVSYLLLSKAAKGVEKSFXXXXX 612
            VPE   +    +S  + + E  EA  LG    P+++GP++YL L K  KG  + F     
Sbjct: 125  VPEFNKNRILKFSWKQILEETDEALLLGYKVKPIILGPITYLWLGKI-KG--EYFDRLDL 181

Query: 613  XXXXXXVYKEVIAELKAAGASWIQFDEPTLVKDPESHQLAAFSAAYTELESTLSGLNVLV 792
                  +YK+V+ EL      ++Q DEP LV D       A+S AY  L  T     +L+
Sbjct: 182  LKNILPIYKQVLRELSQRNIDFVQIDEPALVLDLPEKWKKAYSYAYEYLNGTTK---ILL 238

Query: 793  ETYFADVPAESYKTLTSLSSVTAYGF--DLERGTKTLELVKSGFPAGKYLFAGVVDGRYI 966
             TYF  +       +  +  +  YG   DL  G   L    S  P    L  GV++GR +
Sbjct: 239  TTYFDSIE----HNIEYIRDLPIYGIHIDLVFGKYNLFDFNSKLPKEWILSLGVINGRNV 294

Query: 967  WADDLAASLATLQSLEAIVGKDKLVVSTSCSLMHTAVDLVNETKLDDEIKSWLAFAAQKV 1146
            W  DL     ++ ++  +  + KL++ +SCSL+H+ +DL  E  LD E K W +FA QK 
Sbjct: 295  WRADLIKLFKSISTI--LKFRKKLLIGSSCSLLHSPIDLQKEKNLDKESKKWFSFAVQKC 352

Query: 1147 VEVNALAKALAGQKDEXXXXXXXXXXXXXXXXXXVTNEEVQKAATALKGSDHRRATTVSA 1326
             E++ L+KAL  + D                   V   EVQ   + +   + +R+ + + 
Sbjct: 353  TELSLLSKAL-NKNDTDSIQKWCSSIYERNFSKRVQKIEVQNRLSEILNVNFKRSDSYNI 411

Query: 1327 RLDAQQKKLNLPVLPTTTIGSFPQTVELRRVRREYKAKKISEEEYTNAIKEEISKVVKIQ 1506
            R   Q+KK NLP+LPTTTIGSFPQT+++R++RR+YK   I++ +Y   IK+ I +V+K Q
Sbjct: 412  RSREQKKKFNLPILPTTTIGSFPQTLQIRKLRRDYKQGLINDVDYEIGIKKHIKEVIKEQ 471

Query: 1507 EELDIDVLVHGEPERNDMVEYFGEQLSGFTFTANGWVQSYGSRCVKPPIIYGDVSRPNPM 1686
            E+L IDVLVHGEPERNDMVEYFGE L GF FT NGWVQSYGSRCVKPPII GDVSR  P+
Sbjct: 472  EKLGIDVLVHGEPERNDMVEYFGENLDGFIFTDNGWVQSYGSRCVKPPIIIGDVSRLKPI 531

Query: 1687 TVFWSKMAQSMTARPMKGMLTGPVTILNWSFVRNDQPRFETCYQIALAIKKEVEDLEAGG 1866
            TV WSK AQS+T +P+K MLTGPVTIL WSF R D    +   QI LA++ EV DLE   
Sbjct: 532  TVKWSKYAQSLTDKPVKAMLTGPVTILFWSFPREDISLEKIAKQIGLALRDEVLDLEKEK 591

Query: 1867 IQVIQIDEAALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDTTQIHTHMCYSNFNDIIQ 2046
            I++IQIDE ALREGLPLRKS    YL WAV +FR+++ GV++TTQIHTHMCY  F+DI+ 
Sbjct: 592  IEIIQIDEPALREGLPLRKSLWNEYLSWAVDAFRLSSSGVKNTTQIHTHMCYCEFHDIMH 651

Query: 2047 SIINMDADVITIENSRSDEKLLSVFREGVVYGAGIGPGVYDIHSPRIPSKEEIADRVNKM 2226
            +I  +DADVITIE +RSD +LL  F+    Y   IGPGVYDIHS  IPS   I   +NK 
Sbjct: 652  AISFLDADVITIETARSDMELLKSFKT-FKYPNEIGPGVYDIHSSNIPSITSIKFLLNKA 710

Query: 2227 LAVLDTNILWVNPDCGLKTRKYAEVKPALTNMVEAAKQIRAELAK 2361
            +A +    +WVNPDCGLKTR + E   AL NMV AAK++R ++ K
Sbjct: 711  IAYIPVERIWVNPDCGLKTRNWNETILALKNMVCAAKEMRDKIKK 755

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>Q6LSD6:METE_PHOPR 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase|
            - Photobacterium profundum (Photobacterium sp. (strain
            SS9))
          Length = 766

 Score =  626 bits (1615), Expect = e-178
 Identities = 346/766 (45%), Positives = 465/766 (60%), Gaps = 5/766 (0%)
 Frame = +1

Query: 70   KMASHIVGYPRMGPKRELKFALESFWDGKSSAEDLEKVATDLRASIWKQMAGAGIKYIPS 249
            K  +HI+GYPR+G +RELKFA E +W G+    +L++V + LR   W    GAG+ Y+  
Sbjct: 8    KTVTHILGYPRVGSQRELKFAQEKYWRGEIEQNELKEVGSLLRHRHWGDQVGAGLDYVSV 67

Query: 250  NTFAYYDQVLDTTAMLGAVPDRYSWTGGEINLSTYFSMARGNA----TVPAMEMTKWFDT 417
              FA+YD VL+T+ +LG +P R+    G  +L T F +ARG A    +  A +MTKWF+T
Sbjct: 68   GDFAWYDHVLNTSMLLGHIPKRHD--NGFPDLDTLFRIARGKAPTGCSCAASDMTKWFNT 125

Query: 418  NYHFIVPELGPDTKFSYSSHKAINEYKEAKALGVDTVPVLVGPVSYLLLSKAAKGVEKSF 597
            NYH+IVPE   D +F+ S  +   E  EAK  G    PVL+GPVSYL L K     E+ F
Sbjct: 126  NYHYIVPEFTEDDQFNVSWQQLFGEVAEAKKAGHKVKPVLLGPVSYLWLGKEK---EEGF 182

Query: 598  XXXXXXXXXXXVYKEVIAELKAAGASWIQFDEPTLVKDPESHQLAAFSAAYTELESTLSG 777
                        Y++++++L+A G  W+Q DEP L  +       +F  AY  L      
Sbjct: 183  DRLSLLPRLLAAYQKILSKLEALGVEWVQIDEPVLALELPKPWAESFKLAYQVLNGNTK- 241

Query: 778  LNVLVETYFADVPAESYKTLTSLSSVTAYGFDLERGTKTLELVKSGFPAGKYLFAGVVDG 957
              +L+ TYF ++     K +    ++     DL    + L  V    P    L AGVV+G
Sbjct: 242  --LLLTTYFDNITHHLDKIVEL--NIDGLHVDLSAAPEQLNAVVDALPENWVLSAGVVNG 297

Query: 958  RYIWADDLAASLATLQSLEAIVGKDKLVVSTSCSLMHTAVDLVNETKLDDEIKSWLAFAA 1137
            R +W  DL+  L  LQ ++A +G+ +L V +SCSL+H+ +DL  ET L  E++ WL+FA 
Sbjct: 298  RNVWRADLSHVLDVLQPVKAKLGQ-RLWVGSSCSLLHSPIDLDLETDLSPEVRQWLSFAK 356

Query: 1138 QKVVEVNALAKALAGQKDEXXXXXXXXXXXXXXXXXX-VTNEEVQKAATALKGSDHRRAT 1314
            QK  E   +A+AL G                       V N +V++   A+  +   R  
Sbjct: 357  QKCREF-LVAQALDGNAIAIQECAKYSAPIKARATSALVNNPDVRQRTNAITAALAERTA 415

Query: 1315 TVSARLDAQQKKLNLPVLPTTTIGSFPQTVELRRVRREYKAKKISEEEYTNAIKEEISKV 1494
              + R   Q+  LNLP+LPTTTIGSFPQT E+R  RR++KA  ++E +Y  A+K  I+  
Sbjct: 416  PYAERTRQQRAALNLPLLPTTTIGSFPQTNEIRTQRRDFKAGYLTEADYNTALKGHIADA 475

Query: 1495 VKIQEELDIDVLVHGEPERNDMVEYFGEQLSGFTFTANGWVQSYGSRCVKPPIIYGDVSR 1674
            ++ QE+LD+DV VHGE ERNDMVEYF E L GF  T  GWVQSYGSRCVKP +I  D+ R
Sbjct: 476  IQRQEDLDLDVFVHGEAERNDMVEYFAELLEGFAVTRFGWVQSYGSRCVKPAVIVSDIYR 535

Query: 1675 PNPMTVFWSKMAQSMTARPMKGMLTGPVTILNWSFVRNDQPRFETCYQIALAIKKEVEDL 1854
              PMTV W+  AQS+T + +KGMLTGPVTIL W+F R D PR     QIALA++ EV DL
Sbjct: 536  AKPMTVEWTTYAQSLTDKLVKGMLTGPVTILGWTFPREDLPRQGIANQIALALRDEVSDL 595

Query: 1855 EAGGIQVIQIDEAALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDTTQIHTHMCYSNFN 2034
            +A GI++IQIDE A+REGLPL++S+   YLDWAV++F+I+    +  TQIHTHMCYS FN
Sbjct: 596  QAAGIKIIQIDEPAIREGLPLKESQWQAYLDWAVNAFKISAASAEPQTQIHTHMCYSEFN 655

Query: 2035 DIIQSIINMDADVITIENSRSDEKLLSVFREGVVYGAGIGPGVYDIHSPRIPSKEEIADR 2214
             II+S+  +DADVITIE SRSD +LL  F E   Y   IGPGVYDIHSP IPS E+I   
Sbjct: 656  HIIKSVAALDADVITIETSRSDMELLKAFEE-FDYPNEIGPGVYDIHSPNIPSIEQIVHL 714

Query: 2215 VNKMLAVLDTNILWVNPDCGLKTRKYAEVKPALTNMVEAAKQIRAE 2352
            V K   ++    LW+NPDCGLKTR + E + AL +MVEA K++R +
Sbjct: 715  VEKAETLIPIERLWINPDCGLKTRNWEETEAALRSMVEATKKLREQ 760

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>Q8KRG6:METE_VIBHA 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase|
            - Vibrio harveyi
          Length = 760

 Score =  626 bits (1614), Expect = e-178
 Identities = 350/767 (45%), Positives = 459/767 (59%), Gaps = 8/767 (1%)
 Frame = +1

Query: 79   SHIVGYPRMGPKRELKFALESFWDGKSSAEDLEKVATDLRASIWKQMAGAGIKYIPSNTF 258
            +HI+GYPR+G KRELKFA E +W G+    +L++V   LR   W   A AG+ +  +  F
Sbjct: 5    THILGYPRIGEKRELKFAQEKYWRGEIEQTELKQVGATLREKNWATQAEAGLSFATAGDF 64

Query: 259  AYYDQVLDTTAMLGAVPDRYSWTGGEINLSTYFSMARGNATV-------PAMEMTKWFDT 417
            A+YD VL TT +LG  P R++   G  +L T F + RG +          A +MTKWF+T
Sbjct: 65   AWYDHVLTTTLLLGHTPKRHA--NGFPDLDTLFKVGRGQSQAGCGCSGAAASDMTKWFNT 122

Query: 418  NYHFIVPELGPDTKFSYSSHKAINEYKEAKALGVDTVPVLVGPVSYLLLSKAAKGVEKSF 597
            NYH+IVPE   D  F  S  +   E  +A  LG +  PVL+GP+SYL L K    +E+ F
Sbjct: 123  NYHYIVPEFSKDDSFEVSWPQLFEEVNDAIKLGHNVKPVLLGPLSYLYLGKE---IEEDF 179

Query: 598  XXXXXXXXXXXVYKEVIAELKAAGASWIQFDEPTLVKDPESHQLAAFSAAYTELESTLSG 777
                        Y+ ++++L   G  W+Q DEP L  + E     AF  AY  + S +  
Sbjct: 180  DRLTLLPRLLTAYQAILSKLANQGVEWVQIDEPILSLELEEKWGDAFKLAYQVIRSDVK- 238

Query: 778  LNVLVETYFADVPAESYKTLTSLSSVTAYGFDLERGTKTLELVKSGFPAGKYLFAGVVDG 957
              VL+ TYF  V +++   +  L  V     DL    + L+ V    P G  L AGVV+G
Sbjct: 239  --VLLTTYFDSV-SDTLDKIVELP-VDGLHIDLSASPEQLDEVVEKLPQGWVLSAGVVNG 294

Query: 958  RYIWADDLAASLATLQSLEAIVGKDKLVVSTSCSLMHTAVDLVNETKLDDEIKSWLAFAA 1137
            R +W  DL+A    LQ ++  +G D L V++SCSL+H+ VDL  E  L DE+KSW AFA 
Sbjct: 295  RNVWRSDLSAQRERLQPVKDKLG-DNLWVASSCSLLHSPVDLDLEPALSDEVKSWFAFAK 353

Query: 1138 QKVVEVNALAKALAGQKDEXXXXXXXXXXXXXXXXXXVTNE-EVQKAATALKGSDHRRAT 1314
            QKV EV  L +AL G  +                     N+  VQ    ++  S   R+ 
Sbjct: 354  QKVTEVALLGRALDGDHNAILVCDTYSQPIKDRKTAAHVNKPHVQARLNSISASLTERSA 413

Query: 1315 TVSARLDAQQKKLNLPVLPTTTIGSFPQTVELRRVRREYKAKKISEEEYTNAIKEEISKV 1494
              + R   Q + L LP+LPTTTIGSFPQT E+R  R  +++ ++S ++Y  A+K  I+  
Sbjct: 414  PYAERAAHQAEVLGLPLLPTTTIGSFPQTSEIRVQRSAFRSGQLSTDDYHQALKGHIADA 473

Query: 1495 VKIQEELDIDVLVHGEPERNDMVEYFGEQLSGFTFTANGWVQSYGSRCVKPPIIYGDVSR 1674
            V+ QE LD+DVLVHGE ERNDMVEYF E L+GF  T  GWVQSYGSRCVKP I+  D+ R
Sbjct: 474  VRRQEALDLDVLVHGEAERNDMVEYFAENLAGFQTTKFGWVQSYGSRCVKPAIVVADIER 533

Query: 1675 PNPMTVFWSKMAQSMTARPMKGMLTGPVTILNWSFVRNDQPRFETCYQIALAIKKEVEDL 1854
              P+TV WS  AQS+T + MKGMLTGPVTIL W+F R D  R     Q+ALA++ EV DL
Sbjct: 534  EKPITVEWSTYAQSLTNKQMKGMLTGPVTILCWTFPREDITRKAIADQLALALRDEVSDL 593

Query: 1855 EAGGIQVIQIDEAALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDTTQIHTHMCYSNFN 2034
            +  GI +IQIDE A+REGLPL+K +H  YL WAV +F+I     +  TQIHTHMCYS FN
Sbjct: 594  QQAGINIIQIDEPAIREGLPLKKRDHKAYLQWAVDAFKIAAASAKPETQIHTHMCYSEFN 653

Query: 2035 DIIQSIINMDADVITIENSRSDEKLLSVFREGVVYGAGIGPGVYDIHSPRIPSKEEIADR 2214
            +II S+  +DADVITIE SRS+ +LL  F E   Y   IGPGVYDIHSP IPS+E I + 
Sbjct: 654  EIIDSVAALDADVITIETSRSNMELLKAF-EDFNYPNEIGPGVYDIHSPNIPSEEWIEEL 712

Query: 2215 VNKMLAVLDTNILWVNPDCGLKTRKYAEVKPALTNMVEAAKQIRAEL 2355
            + K    +    LWVNPDCGLKTR ++E + AL N+V AAK++RAEL
Sbjct: 713  IKKAAEKIPAQRLWVNPDCGLKTRNWSETEAALANLVSAAKKLRAEL 759

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>Q9CG55:METE_LACLA 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase|
            - Lactococcus lactis subsp. lactis (Streptococcus lactis)
          Length = 759

 Score =  625 bits (1611), Expect = e-178
 Identities = 341/767 (44%), Positives = 477/767 (62%), Gaps = 7/767 (0%)
 Frame = +1

Query: 73   MASHIVGYPRMGPKRELKFALESFWDGKSSAEDLEKVATDLRASIWKQMAGAGIKYIPSN 252
            M   I+ +PR+G  RELKFALE ++  + + E+L+ VA ++R   WK    AGI    SN
Sbjct: 3    MKKSIIAFPRIGSNRELKFALEKYFRKEITEEELQTVAKEIRLENWKSQKEAGIDSPISN 62

Query: 253  TFAYYDQVLDTTAMLGAVPDRYSWTGGEIN-LSTYFSMARG----NATVPAMEMTKWFDT 417
             F++YDQ LD +  LGA+P  Y     E++ L T F++ARG       V A  M KWF+T
Sbjct: 63   DFSFYDQTLDLSIALGAIPGSYK--NLELSELDTLFALARGFQDEQNDVKARPMKKWFNT 120

Query: 418  NYHFIVPELGPDTKFSYSSHKAINEYKEAKALGVDTVPVLVGPVSYLLLSKAAKGVEKSF 597
            NYH++VPE+  DT    +  K +NEYKEAK+ G +T P ++GP ++L+L+    G  K  
Sbjct: 121  NYHYLVPEINKDTIIKANFSKLLNEYKEAKSAGFETRPTIIGPYTFLVLADYKSGATKD- 179

Query: 598  XXXXXXXXXXXVYKEVIAELKAAGASWIQFDEPTLVKDPESHQLAAFSAAYTELESTLSG 777
                        ++ ++ EL   G  W+Q +EP LV D    +   F + Y EL  + + 
Sbjct: 180  ---TVLSDVIVAFQTLLKELNQLGVEWLQIEEPALVLDQTEEEKKLFVSIYEELLKSKNN 236

Query: 778  LNVLVETYFADVPAESYKTLTSLSSVTAYGFDLERGTKTLELV-KSGFPAGKYLFAGVVD 954
            LN+L++TYF DV  +SYK +  L      G D   G  +L L+ K GFP  K LFAG+V+
Sbjct: 237  LNILLQTYFGDV-RDSYKEIIKLD-FDGIGLDFIEGRDSLALIQKYGFPKKKILFAGLVN 294

Query: 955  GRYIWADDLAASLATLQSLEAIVGKDKLVVSTSCSLMHTAVDLVNETKLDDEIKSWLAFA 1134
            G+ IW ++   +L  L +L+ +     +V++TSCSL H  V + NETKL  EI    +FA
Sbjct: 295  GKNIWRNNYQKTLELLTALDEVAD---IVINTSCSLQHVPVTIKNETKLSKEILKHFSFA 351

Query: 1135 AQKVVEVNALAKALAGQKDEXXXXXXXXXXXXXXXXXXVTNEEVQKAATALKGSDHRRAT 1314
             +K+ E++ ++     +                       N ++++    L   D  R  
Sbjct: 352  TEKLNEIDEISDIYFNKNTSFLKKNVELFENERVRE----NSKLKQKLDKLTEKDFTRQP 407

Query: 1315 TVSARLDAQQKKLNLPVLPTTTIGSFPQTVELRRVRREYKAKKISEEEYTNAIKEEISKV 1494
            ++  R  +Q + LNLPVLPTTTIGSFPQT E+R+VR + K  ++ + +Y   ++E+I + 
Sbjct: 408  SLVERRASQSQSLNLPVLPTTTIGSFPQTAEVRKVRLQNKRGELRQADYDTFLEEKIKEC 467

Query: 1495 VKIQEELDIDVLVHGEPERNDMVEYFGEQLSGFTFTANGWVQSYGSRCVKPPIIYGDVSR 1674
            +K+QE++ +DVLVHGE ERNDMVEYFGE+L G+ FT   WVQSYG+RCVKPPI++ DV+R
Sbjct: 468  LKLQEDIGLDVLVHGEFERNDMVEYFGEKLEGYVFTQKAWVQSYGTRCVKPPIVWTDVTR 527

Query: 1675 PNPMTVFWSKMAQSMTARPMKGMLTGPVTILNWSFVRNDQPRFETCYQIALAIKKEVEDL 1854
            P  MTV WS  AQS T++P+KGMLTGPVTILNWSF R D     +  Q+ALA+++EV DL
Sbjct: 528  PEAMTVRWSAYAQSQTSKPVKGMLTGPVTILNWSFPREDISLKASTLQLALAVQEEVLDL 587

Query: 1855 EAGGIQVIQIDEAALREGLPLRKSE-HAFYLDWAVHSFRITNCGVQDTTQIHTHMCYSNF 2031
            E  GI++IQIDEAALRE LPLRKS+ +  YLDWA+ +FR+ +  V+  TQIHTHMCYS F
Sbjct: 588  EKAGIKIIQIDEAALREKLPLRKSDWYKEYLDWAIPAFRLVHSKVKPETQIHTHMCYSEF 647

Query: 2032 NDIIQSIINMDADVITIENSRSDEKLLSVFREGVVYGAGIGPGVYDIHSPRIPSKEEIAD 2211
             DII SI  MDADVI+ E SRS+  ++   +    +   +GPGVYDIHSPRIPS +EI +
Sbjct: 648  EDIIPSIDAMDADVISFEASRSELSIIDALK-AHHFKTLVGPGVYDIHSPRIPSVKEIQN 706

Query: 2212 RVNKMLAVLDTNILWVNPDCGLKTRKYAEVKPALTNMVEAAKQIRAE 2352
            ++ K+L  L    +WVNPDCGLKTR  AE  P+L ++VEA + +R E
Sbjct: 707  QLEKILDKLPIEQVWVNPDCGLKTRGNAETIPSLRHLVEATRVLRKE 753

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>Q97S31:METE_STRPN 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase|
            - Streptococcus pneumoniae
          Length = 749

 Score =  624 bits (1609), Expect = e-178
 Identities = 351/766 (45%), Positives = 474/766 (61%), Gaps = 5/766 (0%)
 Frame = +1

Query: 73   MASHIVGYPRMGPKRELKFALESFWDGKSSAEDLEKVATDLRASIWKQMAGAGIKYIPSN 252
            M++ I+G+PR+G  RELKF  E ++  + S E+L   A DLRA  W  +   GI  IPSN
Sbjct: 1    MSTTIIGFPRLGEFRELKFTTEKYFRKEISEEELLAAAKDLRAKHWNIVKEKGITEIPSN 60

Query: 253  TFAYYDQVLDTTAMLGAVPDRYSWTGGEINLSTYFSMARG----NATVPAMEMTKWFDTN 420
             F++YD  LD   +   VP          +L  YF++ RG       V A+ M KWF+TN
Sbjct: 61   DFSHYDNFLDAAFLFNVVPASVQNLDLS-DLERYFALGRGYQGEKGDVRALPMKKWFNTN 119

Query: 421  YHFIVPELGPDTKFSYSSHKAINEYKEAKALGVDTVPVLVGPVSYLLLSKAAKGVEKSFX 600
            YH+IVP+   DT+   + HK  +E++EAK LG++T PVLVGP ++L LS   +GV+    
Sbjct: 120  YHYIVPKFEKDTQVKLAGHKIFDEFQEAKELGLNTRPVLVGPFTFLQLSDFEEGVKAD-- 177

Query: 601  XXXXXXXXXXVYKEVIAELKAAGASWIQFDEPTLVKDPESHQLAAFSAAYTELESTLSGL 780
                       Y+EV A+L   GA+ IQ DE  LVKD  + + A F   Y +L +   GL
Sbjct: 178  --DFVDSLVAAYQEVFAKLAELGATRIQLDEAALVKDLTAEEKALFLNLYNKLLADKKGL 235

Query: 781  NVLVETYFADVPAESYKTLTSLSSVTAYGFDLERGTKTLELVKSGFPAGKYLFAGVVDGR 960
             VL++TYF DV  + Y  L +L  V A G D   G KTLELVK GFPA K L+ G+V+G+
Sbjct: 236  EVLLQTYFGDV-RDVYADLVNLP-VDAIGLDFVEGKKTLELVKGGFPADKTLYVGIVNGK 293

Query: 961  YIWADDLAASLATLQSLEAIVGKDKLVVSTSCSLMHTAVDLVNETKLDDEIKSWLAFAAQ 1140
             IW ++   SLA L+ + A    + +V+++SCSL+H      NE + +  + +  AFA +
Sbjct: 294  NIWRNNYEKSLAVLEQIPA----ENIVLTSSCSLLHVPFTTANE-EFEPALLNHFAFAVE 348

Query: 1141 KVVEVNALAKALAGQKDEXXXXXXXXXXXXXXXXXXVTNEEVQKAATALKGSDHRRATTV 1320
            K+ E+  L     GQ  E                    N E++     L  +D+ R    
Sbjct: 349  KLDEIRDLDAIRNGQGSEALAANKELFATERVGE----NAELRARIAGLTDADYTRLPAF 404

Query: 1321 SARLDAQQKKLNLPVLPTTTIGSFPQTVELRRVRREYKAKKISEEEYTNAIKEEISKVVK 1500
            + R   Q++   LP LPTTTIGSFPQT E+R  R  Y+  ++S++EY   + E I + +K
Sbjct: 405  AEREAIQEEAFKLPALPTTTIGSFPQTKEVRAKRLAYRKGELSQKEYDAFLAETIDEWIK 464

Query: 1501 IQEELDIDVLVHGEPERNDMVEYFGEQLSGFTFTANGWVQSYGSRCVKPPIIYGDVSRPN 1680
             QE++D DVLVHGE ERNDMVEYFG+ LSG+ F+ NGWVQSYG R VKPPII+GDV+R N
Sbjct: 465  WQEDIDFDVLVHGEFERNDMVEYFGQNLSGYLFSKNGWVQSYGMRGVKPPIIWGDVTRLN 524

Query: 1681 PMTVFWSKMAQSMTARPMKGMLTGPVTILNWSFVRNDQPRFETCYQIALAIKKEVEDLEA 1860
            P+TV WS  AQS T +P+KGMLTGPVTILNWSF R D    ++  QIALAIK EV DLEA
Sbjct: 525  PITVKWSSYAQSRTNKPVKGMLTGPVTILNWSFPREDISIKDSTLQIALAIKDEVLDLEA 584

Query: 1861 GGIQVIQIDEAALREGLPLRKSE-HAFYLDWAVHSFRITNCGVQDTTQIHTHMCYSNFND 2037
             G+++IQIDEAALRE LPLR+S+ +  YLDWA+ +FR+ +  V   TQIHTHMCYS F D
Sbjct: 585  AGVKIIQIDEAALREKLPLRRSDWYEDYLDWAIPAFRLVHSTVAPDTQIHTHMCYSEFTD 644

Query: 2038 IIQSIINMDADVITIENSRSDEKLLSVFREGVVYGAGIGPGVYDIHSPRIPSKEEIADRV 2217
            II +I NMDADVI+ E +RS+ ++L   +    +   +GPGVYDIHSPR+P++ EI + +
Sbjct: 645  IIPAIDNMDADVISFEANRSNLEILDELK-AKNFQTEVGPGVYDIHSPRVPNEGEIDNTI 703

Query: 2218 NKMLAVLDTNILWVNPDCGLKTRKYAEVKPALTNMVEAAKQIRAEL 2355
              +LA + +  +W+NPDCGLKTR   E K +L  +VEAAK  R +L
Sbjct: 704  EAILAKVPSKKVWINPDCGLKTRGIPETKESLIRLVEAAKAAREKL 749

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>Q8FQB2:METE_COREF 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase|
            - Corynebacterium efficiens
          Length = 754

 Score =  624 bits (1608), Expect = e-178
 Identities = 352/771 (45%), Positives = 469/771 (60%), Gaps = 11/771 (1%)
 Frame = +1

Query: 76   ASHIVGYPRMGPKRELKFALESFWDGKSSAEDLEKVATDLRASIWKQMAGAGIKYIPSNT 255
            +S I G PR+G  RELKFALE FW G  S  +L + AT L      Q+A AG+  IP+  
Sbjct: 6    SSTIAGVPRIGAHRELKFALEGFWSGTVSGRELGQTATTLTNDYCDQLAAAGLDSIPTAG 65

Query: 256  FAYYDQVLDTTAMLGAVPDRYSWTGGEIN------LSTYFSMARGNATVPAMEMTKWFDT 417
             +YYD +LDTTA+LG  P+R+       N      +  YF+ ARG A +PA  MTKWFDT
Sbjct: 66   RSYYDAMLDTTALLGVFPERFQNLDDHPNDGLPAHIDRYFATARGTAELPASAMTKWFDT 125

Query: 418  NYHFIVPELGPDTKFSYSSHKAINEYKEAKALGVDTVPVLVGPVSYLLLSKAAKGVEKSF 597
            NYH++VPEL  DT+F       + +  +    G D  PVL+GP++YL LS+   G +   
Sbjct: 126  NYHYLVPELSADTRFILDDTALLTDIHDQLTRGHDVRPVLIGPLTYLSLSRTTDGSDP-- 183

Query: 598  XXXXXXXXXXXVYKEVIAELKAAGASWIQFDEPTLVKDPESHQLAAFSAAYTELESTLSG 777
                       V++ ++A+L      W+Q DEP+LV D     L    A Y  L +T  G
Sbjct: 184  --LDHLETLFEVFERLLAKLPTP---WVQLDEPSLVTDVAPEVLERVRAGYARL-ATRGG 237

Query: 778  LNVLVETYFADVPAESYKTLTSLSSVTAYGFDL-ERGTKTLELVKSGFPAGKYLFAGVVD 954
              V V TYF     ++  TL  L  + A G DL   G   LE  K      + L AG+VD
Sbjct: 238  --VFVNTYFG-AGDQALDTLAGLG-LGAIGVDLVSDGVTALEAWKGE----ELLVAGIVD 289

Query: 955  GRYIWADDLAASLATLQSLEAIVGKDKLVVSTSCSLMHTAVDLVNETKLDDEIKSWLAFA 1134
            GR +W  DL A+L TL+ L+A   +  + VSTSCSL+H    L  ET L+ E++ WLAF 
Sbjct: 290  GRNVWRTDLCAALGTLRRLQA---RGPVAVSTSCSLLHVPYALTAETGLNPEVREWLAFG 346

Query: 1135 AQKVVEVNALAKALAGQKDEXXXXXXXXXXXXXXXXXXVTNEEVQKAATALKGSD----H 1302
             +KV EV ALA ALAG+ +E                     +      TA + +D     
Sbjct: 347  EEKVREVVALADALAGEINESLFDAAAAALA----------DRRHSVLTAARDADITDAD 396

Query: 1303 RRATTVSARLDAQQKKLNLPVLPTTTIGSFPQTVELRRVRREYKAKKISEEEYTNAIKEE 1482
            R  +    R  AQ + L+LP LPTTTIGSFPQT E+R  R  Y+A  ++ E+Y +A++ E
Sbjct: 397  RSRSPFEVRAAAQDEALDLPPLPTTTIGSFPQTREIRSARARYRAGHLTPEQYEDAMRAE 456

Query: 1483 ISKVVKIQEELDIDVLVHGEPERNDMVEYFGEQLSGFTFTANGWVQSYGSRCVKPPIIYG 1662
            I++V++ QE+L +DVLVHGEPERNDMV+YF E L GF  T NGWVQSYGSRCV+PPI++G
Sbjct: 457  IAQVIRAQEDLGLDVLVHGEPERNDMVQYFAELLDGFLTTTNGWVQSYGSRCVRPPILFG 516

Query: 1663 DVSRPNPMTVFWSKMAQSMTARPMKGMLTGPVTILNWSFVRNDQPRFETCYQIALAIKKE 1842
             V+RP PMTV W   AQS+T RP+KGMLTGPVTIL WSFVR+DQP   T  QIALA+++E
Sbjct: 517  TVTRPEPMTVRWFAHAQSLTNRPVKGMLTGPVTILAWSFVRDDQPLAVTADQIALALREE 576

Query: 1843 VEDLEAGGIQVIQIDEAALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDTTQIHTHMCY 2022
            + DL   G ++IQ+DE A+RE LPLR++E   Y  WAV +FR++     D  QIHTHMCY
Sbjct: 577  ITDLVDAGAKIIQVDEPAIRELLPLRRAEQDAYTRWAVGAFRLSTSTAPDHVQIHTHMCY 636

Query: 2023 SNFNDIIQSIINMDADVITIENSRSDEKLLSVFREGVVYGAGIGPGVYDIHSPRIPSKEE 2202
            S FN++I+SII++DADV TIE +RSD ++L+  +    +  G+GPGV+DIHSPR+P   E
Sbjct: 637  SEFNELIRSIIDLDADVTTIEAARSDMQVLAALKSS-GFHLGVGPGVWDIHSPRVPELAE 695

Query: 2203 IADRVNKMLAVLDTNILWVNPDCGLKTRKYAEVKPALTNMVEAAKQIRAEL 2355
            ++  ++  L  +D   LWVNPDCGLKTR + E   +L  +V AA+Q R +L
Sbjct: 696  VSQLLSSALESVDPRRLWVNPDCGLKTRGWEETTASLKVLVAAAEQARTDL 746

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>Q8DQT2:METE_STRR6 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase|
            - Streptococcus pneumoniae (strain ATCC BAA-255 / R6)
          Length = 749

 Score =  622 bits (1605), Expect = e-177
 Identities = 351/766 (45%), Positives = 472/766 (61%), Gaps = 5/766 (0%)
 Frame = +1

Query: 73   MASHIVGYPRMGPKRELKFALESFWDGKSSAEDLEKVATDLRASIWKQMAGAGIKYIPSN 252
            M++ I+G+PR+G  RELKF  E ++  + S E+L   A DLRA  W  +   GI  IPSN
Sbjct: 1    MSTTIIGFPRLGEFRELKFTTEKYFRKEISEEELLAAAKDLRAKHWNIVKEKGITEIPSN 60

Query: 253  TFAYYDQVLDTTAMLGAVPDRYSWTGGEINLSTYFSMARG----NATVPAMEMTKWFDTN 420
             F++YD  LD   +   VP          +L  YF++ RG       V A+ M KWF+TN
Sbjct: 61   DFSHYDNFLDAAFLFNVVPASVQNLDLS-DLERYFALGRGYQGEKGDVRALPMKKWFNTN 119

Query: 421  YHFIVPELGPDTKFSYSSHKAINEYKEAKALGVDTVPVLVGPVSYLLLSKAAKGVEKSFX 600
            YH+IVP+   DT+   + HK  +E++EAK LG++T PVLVGP ++L LS   +GV+    
Sbjct: 120  YHYIVPKFEKDTQVKLAGHKIFDEFQEAKELGLNTRPVLVGPFTFLQLSDFEEGVKAD-- 177

Query: 601  XXXXXXXXXXVYKEVIAELKAAGASWIQFDEPTLVKDPESHQLAAFSAAYTELESTLSGL 780
                       Y+EV A+L   GA+ IQ DE  LVKD  + + A F   Y +L +   GL
Sbjct: 178  --DFVDSFVAAYQEVFAKLADLGATRIQLDEAALVKDLTAEEKALFLNLYNKLLADKKGL 235

Query: 781  NVLVETYFADVPAESYKTLTSLSSVTAYGFDLERGTKTLELVKSGFPAGKYLFAGVVDGR 960
             VL +TYF DV  + Y  L +L  V A G D   G KTLELVK GFPA K L+ G+V+G+
Sbjct: 236  EVLFQTYFGDV-RDVYADLVNLP-VDAIGLDFVEGKKTLELVKGGFPADKTLYVGIVNGK 293

Query: 961  YIWADDLAASLATLQSLEAIVGKDKLVVSTSCSLMHTAVDLVNETKLDDEIKSWLAFAAQ 1140
             IW ++   SL  L+ + A    + +V+++SCSL+H      NE + +  + +  AFA +
Sbjct: 294  NIWRNNYEKSLTVLEQIPA----ENIVLTSSCSLLHVPFTTANE-EFEPALLNHFAFAVE 348

Query: 1141 KVVEVNALAKALAGQKDEXXXXXXXXXXXXXXXXXXVTNEEVQKAATALKGSDHRRATTV 1320
            K+ E+  L     GQ  E                    N E++     L  +D+ R    
Sbjct: 349  KLDEIRDLDAIRNGQGSEALAANKELFATERVGE----NAELRARIAGLTDADYTRLPAF 404

Query: 1321 SARLDAQQKKLNLPVLPTTTIGSFPQTVELRRVRREYKAKKISEEEYTNAIKEEISKVVK 1500
            + R   Q++   LP LPTTTIGSFPQT E+R  R  Y+  ++S++EY   + E I + +K
Sbjct: 405  AEREAIQEEAFKLPALPTTTIGSFPQTKEVRAKRLAYRKGELSQKEYDAFLAETIDEWIK 464

Query: 1501 IQEELDIDVLVHGEPERNDMVEYFGEQLSGFTFTANGWVQSYGSRCVKPPIIYGDVSRPN 1680
             QE++D DVLVHGE ERNDMVEYFG+ LSG+ F+ NGWVQSYG R VKPPII+GDV+R N
Sbjct: 465  WQEDIDFDVLVHGEFERNDMVEYFGQNLSGYLFSKNGWVQSYGMRGVKPPIIWGDVTRLN 524

Query: 1681 PMTVFWSKMAQSMTARPMKGMLTGPVTILNWSFVRNDQPRFETCYQIALAIKKEVEDLEA 1860
            P+TV WS  AQS T +P+KGMLTGPVTILNWSF R D    ++  QIALAIK EV DLEA
Sbjct: 525  PITVKWSSYAQSRTNKPVKGMLTGPVTILNWSFPREDISIKDSTLQIALAIKDEVLDLEA 584

Query: 1861 GGIQVIQIDEAALREGLPLRKSE-HAFYLDWAVHSFRITNCGVQDTTQIHTHMCYSNFND 2037
             G+++IQIDEAALRE LPLR+S+ +  YLDWA+ +FR+ +  V   TQIHTHMCYS F D
Sbjct: 585  AGVKIIQIDEAALREKLPLRRSDWYEDYLDWAIPAFRLVHSTVAPDTQIHTHMCYSEFTD 644

Query: 2038 IIQSIINMDADVITIENSRSDEKLLSVFREGVVYGAGIGPGVYDIHSPRIPSKEEIADRV 2217
            II +I NMDADVI+ E SRS+ ++L   +    +   +GPGVYDIHSPR+P++ EI + +
Sbjct: 645  IIPAIDNMDADVISFEASRSNLEILDELK-AKNFQTEVGPGVYDIHSPRVPNEGEIDNTI 703

Query: 2218 NKMLAVLDTNILWVNPDCGLKTRKYAEVKPALTNMVEAAKQIRAEL 2355
              +LA + +  +W+NPDCGLKTR   E K +L  +VEAAK  R +L
Sbjct: 704  EAILAKVPSKKVWINPDCGLKTRGIPETKESLIRLVEAAKAAREKL 749

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>Q7VRI8:METE_BLOFL 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase|
            - Blochmannia floridanus
          Length = 769

 Score =  618 bits (1594), Expect = e-176
 Identities = 335/769 (43%), Positives = 461/769 (59%), Gaps = 13/769 (1%)
 Frame = +1

Query: 79   SHIVGYPRMGPKRELKFALESFWDGKSSAEDLEKVATDLRASIWKQMAGAGIKYIPSNTF 258
            SHI+G+PR+G  RELK ALE +W+ K +   L  +   LR   WKQ   +GI  IP   F
Sbjct: 5    SHILGFPRIGLYRELKHALEQYWEKKITENKLLDIGRMLRMRHWKQQINSGINLIPIGDF 64

Query: 259  AYYDQVLDTTAMLGAVPDRYSWTGGEIN-LSTYFSMARG----NATVPAMEMTKWFDTNY 423
            ++YD VLD + ML  +P R+     + N L+  FS+ARG    N T+   EM KWF+TNY
Sbjct: 65   SWYDHVLDMSIMLNNIPTRFHILSQKKNTLNMLFSIARGDSINNTTITPSEMKKWFNTNY 124

Query: 424  HFIVPELGPDTKFSYSSHKAINEYKEAKALGVDTVPVLVGPVSYLLLSKAAKGVEKSFXX 603
            H+IVPE   +  F  +  + + E  EA +L     PVL+GP++YL + K  +   K F  
Sbjct: 125  HYIVPEFVQNQIFKLNCTQLLAEIDEALSLNHPIKPVLLGPLTYLWIGKTKE--TKEFDR 182

Query: 604  XXXXXXXXXVYKEVIAELKAAGASWIQFDEPTLVKDPESHQLAAFSAAYTELESTLSGLN 783
                     VYKE+   L      WIQ DEP LV +     L A+  AY +L  T   + 
Sbjct: 183  LSLLPSLLLVYKEIFNILSKKNIQWIQIDEPALVLELPQTWLKAYLHAYDQLYQTK--IK 240

Query: 784  VLVETYFADVPAESYKTLTSLSSVTAYGFDLER---GTKTLELVKSGFPAGKYLFAGVVD 954
            +L+ TYF  +    Y  L  +  +   G  ++        + L+    P    L AG+++
Sbjct: 241  LLLTTYFGKI----YHQLPIIKQLKVNGLHIDLTNCSDNDISLLHEQLPKKWILSAGIIN 296

Query: 955  GRYIWADDLAASLATLQSLEAIVGKDKLVVSTSCSLMHTAVDLVNETKLDDEIKSWLAFA 1134
            G+ IW  +L         L  I  +  L + +SCSL+H+ +DL  E+KL++ IK+W AFA
Sbjct: 297  GKNIWKTNL---YDWFLKLNTITHQRSLWIGSSCSLLHSPIDLNIESKLNNNIKNWFAFA 353

Query: 1135 AQKVVEVNALAKALAGQKDEXXXXXXXXXXXXXXXXXX-----VTNEEVQKAATALKGSD 1299
             QK  E+  L  AL    ++                       + N +VQ+    +   D
Sbjct: 354  IQKCSEIKLLCDALNSNHNDNSDQQNILKKYYNTNIQRLNSNIINNPQVQERCKNIITLD 413

Query: 1300 HRRATTVSARLDAQQKKLNLPVLPTTTIGSFPQTVELRRVRREYKAKKISEEEYTNAIKE 1479
            H R T    R+  Q  + NLP+ PTTTIGSFPQT E+R++R ++K K+I+E+ Y   I++
Sbjct: 414  HSRKTKHITRMKLQHNRFNLPLYPTTTIGSFPQTSEIRKLRLKFKNKQINEDYYYTHIQQ 473

Query: 1480 EISKVVKIQEELDIDVLVHGEPERNDMVEYFGEQLSGFTFTANGWVQSYGSRCVKPPIIY 1659
             I K+++ QE+LD+D+LVHGEPERNDMVEYFGE L GF  + +GW+QSYGSRC+KPPII 
Sbjct: 474  YIKKIIQEQEKLDLDILVHGEPERNDMVEYFGENLKGFVSSQHGWIQSYGSRCIKPPIII 533

Query: 1660 GDVSRPNPMTVFWSKMAQSMTARPMKGMLTGPVTILNWSFVRNDQPRFETCYQIALAIKK 1839
            GD+SRP P+T+ W   AQS+T +P+KG+LTGP+TI+ WSF R D PR     Q+ALAI+ 
Sbjct: 534  GDISRPIPITIPWINYAQSLTNKPVKGILTGPITIMTWSFAREDIPRHMIALQLALAIRD 593

Query: 1840 EVEDLEAGGIQVIQIDEAALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDTTQIHTHMC 2019
            EV DLE  GI VIQIDE ALREGLPL+KSE ++YL WA+++F+IT   V+D TQIHTHMC
Sbjct: 594  EVMDLEKSGIGVIQIDEPALREGLPLKKSEQSYYLKWAINTFKITVSSVKDNTQIHTHMC 653

Query: 2020 YSNFNDIIQSIINMDADVITIENSRSDEKLLSVFREGVVYGAGIGPGVYDIHSPRIPSKE 2199
            YS FN+II  I+ +D DVI+IE+SRSD +LL   +        IGPG+YDIHS   PS  
Sbjct: 654  YSEFNEIIDDILKLDVDVISIESSRSDLQLLQFIKTAGKKLNEIGPGIYDIHSIHQPSIN 713

Query: 2200 EIADRVNKMLAVLDTNILWVNPDCGLKTRKYAEVKPALTNMVEAAKQIR 2346
            EI D++ K+L  +  + LW+NPDCGLKTR + E++ +L NMV AAK +R
Sbjct: 714  EIMDKLKKLLQYIPKDRLWINPDCGLKTRSWNEIRESLNNMVIAAKTLR 762

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>Q731W2:METE_BACC1 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase|
            - Bacillus cereus (strain ATCC 10987)
          Length = 762

 Score =  617 bits (1590), Expect = e-175
 Identities = 346/761 (45%), Positives = 461/761 (60%), Gaps = 5/761 (0%)
 Frame = +1

Query: 88   VGYPRMGPKRELKFALESFWDGKSSAEDLEKVATDLRASIWKQMAGAGIKYIPSNTFAYY 267
            +GYPR+G +RE K  LE+FW  K   E       ++R    K     GI+ IP   F YY
Sbjct: 8    LGYPRIGLQREWKKTLEAFWSNKIDEEQFLTTMKEIRLQHVKAQQEKGIELIPIGDFTYY 67

Query: 268  DQVLDTTAMLGAVPDRYSWTGGEINLSTYFSMARGNATVPAMEMTKWFDTNYHFIVPELG 447
            D VLDT  MLG +P R+S     +++  YF+MARG+    A EMTKWF+TNYH+IVPE  
Sbjct: 68   DHVLDTAYMLGFIPSRFSEFTSYLDV--YFAMARGSKDHVASEMTKWFNTNYHYIVPEYE 125

Query: 448  PDTKFSYSSHKAINEYKEAKA-LGVDTVPVLVGPVSYLLLSKAAKGVEKSFXXXXXXXXX 624
               + S   ++ +  Y+EAK  LG+D  PV++GP ++L L+K     ++ F         
Sbjct: 126  EGLQISLKDNRPLRLYEEAKQELGIDGKPVILGPYTFLKLAKGY--TQEQFATILKQLVA 183

Query: 625  XXVYKEVIAELKAAGASWIQFDEPTLVKDPESHQLAAFSAAYTELESTLSGLNVLVETYF 804
               Y ++++EL AAGA  IQ DEP +       ++      Y  +   +   N+L++TYF
Sbjct: 184  P--YVQLLSELHAAGAQIIQVDEP-IFASLTKEEVQQAKEIYEAIRKEVPNANLLLQTYF 240

Query: 805  ADVPAESYKTLTSLSSVTAYGFDLERGTK--TLELVKSGFPAGKYLFAGVVDGRYIWADD 978
              V  E+Y+ + +   V++ G D   G +     + K GFPA K L  G +DGR IW  D
Sbjct: 241  DSVE-ENYEEIITFP-VSSIGLDFVHGKEGNLHAISKYGFPADKTLAVGCIDGRNIWRAD 298

Query: 979  LAASLATLQSLEAIVGKDKLVVSTSCSLMHTAVDLVNETKLDDEIKSWLAFAAQKVVEVN 1158
            L   L    +L+  V     +V  SCSL+HT +D   ET L  E+   LAFA QK+ E+ 
Sbjct: 299  LDEVLTLFTTLQKQVQTKDFIVQPSCSLLHTPIDKTEETHLSTELFDALAFANQKLEELV 358

Query: 1159 ALAKALAGQKDEXXXXXXXXXXXXXXXXXXVTN--EEVQKAATALKGSDHRRATTVSARL 1332
             +  AL    +                        E+V+ A TALK  D  R      R 
Sbjct: 359  LIHSALTQGTESIHNELETYRNVHHTIRSSAARNREDVKAARTALKEEDFSRPLPFEKRY 418

Query: 1333 DAQQKKLNLPVLPTTTIGSFPQTVELRRVRREYKAKKISEEEYTNAIKEEISKVVKIQEE 1512
            + QQ  L LP+LPTTTIGSFPQT E+R+ R+E++   IS E+Y   I++E  K ++ QEE
Sbjct: 419  ELQQVALKLPLLPTTTIGSFPQTTEVRQTRKEWRNGVISNEQYEQFIEKETEKWIRYQEE 478

Query: 1513 LDIDVLVHGEPERNDMVEYFGEQLSGFTFTANGWVQSYGSRCVKPPIIYGDVSRPNPMTV 1692
            + +DVLVHGE ER DMVEYFGE+L+GF+FT NGWVQSYGSRCVKPP+IYGDV+  N MT+
Sbjct: 479  IGLDVLVHGEFERTDMVEYFGERLAGFSFTKNGWVQSYGSRCVKPPVIYGDVAFINGMTI 538

Query: 1693 FWSKMAQSMTARPMKGMLTGPVTILNWSFVRNDQPRFETCYQIALAIKKEVEDLEAGGIQ 1872
              +  AQS+T + +KGMLTGPVTILNWSFVRND PR E  YQIALA++ E+E LE+ GI+
Sbjct: 539  KETVYAQSLTEKVVKGMLTGPVTILNWSFVRNDIPRKEVSYQIALALRHEIELLESSGIR 598

Query: 1873 VIQIDEAALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDTTQIHTHMCYSNFNDIIQSI 2052
            VIQ+DE ALREG+PL++ +   Y+ WAV SF +    V + TQIHTHMCYSNF DI+ +I
Sbjct: 599  VIQVDEPALREGMPLKEKDWDAYITWAVQSFLLATSSVANETQIHTHMCYSNFEDIVDAI 658

Query: 2053 INMDADVITIENSRSDEKLLSVFREGVVYGAGIGPGVYDIHSPRIPSKEEIADRVNKMLA 2232
              +DADVI+IE SRS  + +   +    Y  GIG GVYDIHSPR+PSK+E+   V + L 
Sbjct: 659  RALDADVISIETSRSHGEFIDTLKH-TTYEKGIGLGVYDIHSPRVPSKDEMYKIVEQSLK 717

Query: 2233 VLDTNILWVNPDCGLKTRKYAEVKPALTNMVEAAKQIRAEL 2355
            V D    W+NPDCGLKTR+  EV PAL +MV+AAK  R+ L
Sbjct: 718  VCDPKYFWINPDCGLKTRRTEEVIPALEHMVQAAKDARSLL 758

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>Q9KFP1:METE_BACHD 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase|
            - Bacillus halodurans
          Length = 756

 Score =  616 bits (1589), Expect = e-175
 Identities = 352/764 (46%), Positives = 466/764 (60%), Gaps = 3/764 (0%)
 Frame = +1

Query: 73   MASHIVGYPRMGPKRELKFALESFWDGKSSAEDLEKVATDLRASIWKQMAGAGIKYIPSN 252
            M +  +GYPR+G  RE K ALESFW   ++ E L     +LR +  +      +  IP  
Sbjct: 1    MLTSNLGYPRIGENREWKKALESFWANDTTEEQLLATMKELRLNHLRVQQEQEVDLIPVG 60

Query: 253  TFAYYDQVLDTTAMLGAVPDRYSWTGGEINLSTYFSMARGNATVPAMEMTKWFDTNYHFI 432
             F  YD VLD   M G +P R+   G    LSTYF+MARG+    A EMTKW++TNYH+I
Sbjct: 61   DFTLYDHVLDMAVMFGIIPKRFLQQGDTPTLSTYFAMARGSKNAQACEMTKWYNTNYHYI 120

Query: 433  VPELGPDTKFSYSSHKAINEYKEAK-ALGVDTVPVLVGPVSYLLLSKAAKGVEKSFXXXX 609
            VPEL  D     + +  +  Y EAK  LG+D  PV++GP S++   K AKG E+      
Sbjct: 121  VPEL-HDAAPRLTKNAPLEAYLEAKNELGIDGKPVILGPYSFV---KLAKGYEED-KLQE 175

Query: 610  XXXXXXXVYKEVIAELKAAGASWIQFDEPTLVKDPESHQLAAFSAAYTELESTLSGLNVL 789
                   +Y +VI EL  AGA  IQ DEP+LV    + ++A  +  Y ++   ++   + 
Sbjct: 176  TIQSLLPLYIQVIQELVDAGARSIQVDEPSLVTSISAREMALVTRIYEQINEAIADAPLF 235

Query: 790  VETYFADVPAESYKTLTSLSSVTAYGFD-LERGTKTLELVKS-GFPAGKYLFAGVVDGRY 963
            ++TYF  V    Y+ + SL  V   G D +  G K LE +++ GFP  K L AG++DGR 
Sbjct: 236  LQTYFDAV--TFYEEVVSL-PVKGIGLDFVHGGAKNLEALRTFGFPEDKVLAAGIIDGRN 292

Query: 964  IWADDLAASLATLQSLEAIVGKDKLVVSTSCSLMHTAVDLVNETKLDDEIKSWLAFAAQK 1143
            IW  +L      +  LE  V KD+LV+  SCSL+H  V    E KLD  +   LAFA +K
Sbjct: 293  IWISNLRERHELVHQLEQHVAKDRLVLQPSCSLLHVPVTTKREEKLDPTLLGVLAFANEK 352

Query: 1144 VVEVNALAKALAGQKDEXXXXXXXXXXXXXXXXXXVTNEEVQKAATALKGSDHRRATTVS 1323
            + E++ L +  AG + E                          AAT+    + +R  + +
Sbjct: 353  LTELHTLKQLAAGNEAEVKEALEANDDALAALEKSGWR---SGAATSHNLENKKRPQSFN 409

Query: 1324 ARLDAQQKKLNLPVLPTTTIGSFPQTVELRRVRREYKAKKISEEEYTNAIKEEISKVVKI 1503
             R   Q++K  LP+LPTTTIGSFPQT ++RR R  ++  ++S  EY   +K  I K + I
Sbjct: 410  ERRPLQEEKWQLPLLPTTTIGSFPQTKDVRRTRSLWRKGELSTVEYERTMKSYIEKWINI 469

Query: 1504 QEELDIDVLVHGEPERNDMVEYFGEQLSGFTFTANGWVQSYGSRCVKPPIIYGDVSRPNP 1683
            QEEL +DVLVHGE ERNDMVE+FGE+L GF FTANGWVQSYGSRCVKPPIIYG+VS   P
Sbjct: 470  QEELGLDVLVHGEFERNDMVEFFGEKLDGFAFTANGWVQSYGSRCVKPPIIYGNVSFTEP 529

Query: 1684 MTVFWSKMAQSMTARPMKGMLTGPVTILNWSFVRNDQPRFETCYQIALAIKKEVEDLEAG 1863
            MTV  +  AQS+T +P+KGMLTGPVTILNWSFVR+D P     +QIA A+  EV  LE  
Sbjct: 530  MTVAETVYAQSLTDKPVKGMLTGPVTILNWSFVRDDLPLTVIAHQIAEALTHEVTALEEA 589

Query: 1864 GIQVIQIDEAALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDTTQIHTHMCYSNFNDII 2043
            GI++IQIDE A+REGLPL+  +   YLDWAV +FR +   V+ TTQIHTHMCYS F+++I
Sbjct: 590  GIEMIQIDEPAIREGLPLKAEDQQEYLDWAVSAFRASCAHVKATTQIHTHMCYSEFHEMI 649

Query: 2044 QSIINMDADVITIENSRSDEKLLSVFREGVVYGAGIGPGVYDIHSPRIPSKEEIADRVNK 2223
            ++I ++DADVI+IE SRS  +++S F E   Y  GIG GVYDIHSPR+PS+EE+ + + +
Sbjct: 650  EAIDDLDADVISIETSRSHGEMISAF-EKTTYEKGIGLGVYDIHSPRVPSEEEMLNVIRR 708

Query: 2224 MLAVLDTNILWVNPDCGLKTRKYAEVKPALTNMVEAAKQIRAEL 2355
             L VL  ++ WVNPDCGLKTR   E   AL NMV AA+  R EL
Sbjct: 709  ALTVLPASLFWVNPDCGLKTRAEKETVAALKNMVAAARAAREEL 752

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>P05694:METE_YEAST 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase|
            - Saccharomyces cerevisiae (Baker's yeast)
          Length = 767

 Score =  616 bits (1588), Expect = e-175
 Identities = 343/770 (44%), Positives = 467/770 (60%), Gaps = 12/770 (1%)
 Frame = +1

Query: 79   SHIVGYPRMGPKRELKFALESFWDGKSSAEDLEKVATDLRASIWKQMAGAGIKYIPSNTF 258
            S ++G+PR+GP RELK A E +W+GK + ++L KV  DLR   WK    AG+  IPSN F
Sbjct: 4    SAVLGFPRIGPNRELKKATEGYWNGKITVDELFKVGKDLRTQNWKLQKEAGVDIIPSNDF 63

Query: 259  AYYDQVLDTTAMLGAVPDRYSWTGGEIN-LSTYFSMARG---NAT-------VPAMEMTK 405
            ++YDQVLD + +   +PDRY  T  +++ + T F+M RG    AT       V A+EM K
Sbjct: 64   SFYDQVLDLSLLFNVIPDRY--TKYDLSPIDTLFAMGRGLQRKATETEKAVDVTALEMVK 121

Query: 406  WFDTNYHFIVPELGPDTKFSYSSHKAINEYKEAKALGVDTVPVLVGPVSYLLLSKAAKGV 585
            WFD+NYH++ P     T+F  +  K ++E+ EAK LG+ T PVL+GPVSYL L KA K  
Sbjct: 122  WFDSNYHYVRPTFSKTTQFKLNGQKPVDEFLEAKELGIHTRPVLLGPVSYLFLGKADKD- 180

Query: 586  EKSFXXXXXXXXXXXVYKEVIAELKAAGASWIQFDEPTLVKDPESHQLAAFSAAYTELES 765
                           +Y E++++L +AGA+ +Q DEP LV D  ++  AA   AYT    
Sbjct: 181  SLDLEPLSLLEQLLPLYTEILSKLASAGATEVQIDEPVLVLDLPANAQAAIKKAYTYFGE 240

Query: 766  TLSGLNVLVETYFADVPAESYKTLTSLSSVTAYGFDLERGTKTLELVKSGFPAGKYLFAG 945
              +   + + TYF  V   +   +  L  V A   D  R  +  + V +     + L  G
Sbjct: 241  QSNLPKITLATYFGTV-VPNLDAIKGLP-VAALHVDFVRAPEQFDEVVAAIGNKQTLSVG 298

Query: 946  VVDGRYIWADDLAASLATLQSLEAIVGKDKLVVSTSCSLMHTAVDLVNETKLDDEIKSWL 1125
            +VDGR IW +D   S A +      +G D++VV+TS SL+HT VDL NETKLD EIK + 
Sbjct: 299  IVDGRNIWKNDFKKSSAIVNKAIEKLGADRVVVATSSSLLHTPVDLNNETKLDAEIKGFF 358

Query: 1126 AFAAQKVVEVNALAKALAGQKDEXXXXXXXXXXXXXXXXXXVTNEEVQKAATALKGSDHR 1305
            +FA QK+ EV  + K ++GQ                     + +  V+    ++      
Sbjct: 359  SFATQKLDEVVVITKNVSGQDVAAALEANAKSVESRGKSKFIHDAAVKARVASIDEKMST 418

Query: 1306 RATTVSARLDAQQKKLNLPVLPTTTIGSFPQTVELRRVRREYKAKKISEEEYTNAIKEEI 1485
            RA     RL  QQK  NLP+ PTTTIGSFPQT ++R  R ++    IS EEY   I  EI
Sbjct: 419  RAAPFEQRLPEQQKVFNLPLFPTTTIGSFPQTKDIRINRNKFNKGTISAEEYEKFINSEI 478

Query: 1486 SKVVKIQEELDIDVLVHGEPERNDMVEYFGEQLSGFTFTANGWVQSYGSRCVKPPIIYGD 1665
             KV++ QEE+ +DVLVHGEPERNDMV+YFGEQ++G+ FT NGWVQSYGSR V+PPII GD
Sbjct: 479  EKVIRFQEEIGLDVLVHGEPERNDMVQYFGEQINGYAFTVNGWVQSYGSRYVRPPIIVGD 538

Query: 1666 VSRPNPMTVFWSKMAQSMTARPMKGMLTGPVTILNWSFVRNDQPRFETCYQIALAIKKEV 1845
            +SRP  M+V  S  AQS+T++P+KGMLTGP+T L WSF R+D  +     Q+ALA++ EV
Sbjct: 539  LSRPKAMSVKESVYAQSITSKPVKGMLTGPITCLRWSFPRDDVDQKTQAMQLALALRDEV 598

Query: 1846 EDLEAGGIQVIQIDEAALREGLPLRK-SEHAFYLDWAVHSFRITNCGVQDTTQIHTHMCY 2022
             DLEA GI+VIQ+DE ALREGLPLR+ +E + Y  WA  +FR+   GV + TQIH+H CY
Sbjct: 599  NDLEAAGIKVIQVDEPALREGLPLREGTERSAYYTWAAEAFRVATSGVANKTQIHSHFCY 658

Query: 2023 SNFNDIIQSIINMDADVITIENSRSDEKLLSVFREGVVYGAGIGPGVYDIHSPRIPSKEE 2202
            S+ +     I  +DADV++IE S+ D+   +   E   Y   IG G++DIHSPRIPSK+E
Sbjct: 659  SDLDP--NHIKALDADVVSIEFSKKDD--ANYIAEFKNYPNHIGLGLFDIHSPRIPSKDE 714

Query: 2203 IADRVNKMLAVLDTNILWVNPDCGLKTRKYAEVKPALTNMVEAAKQIRAE 2352
               +++ +L        WVNPDCGLKTR + E + +LT+MVEAAK  R +
Sbjct: 715  FIAKISTILKSYPAEKFWVNPDCGLKTRGWEETRLSLTHMVEAAKYFREQ 764

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>Q6KNA9:METE_BACAN 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase|
            - Bacillus anthracis
          Length = 762

 Score =  616 bits (1588), Expect = e-175
 Identities = 347/761 (45%), Positives = 462/761 (60%), Gaps = 5/761 (0%)
 Frame = +1

Query: 88   VGYPRMGPKRELKFALESFWDGKSSAEDLEKVATDLRASIWKQMAGAGIKYIPSNTFAYY 267
            +GYPR+G +RE K  LE+FW  K + E       ++R    K     GI+ IP   F YY
Sbjct: 8    LGYPRIGLQREWKKTLEAFWSNKINEEQFLTTMKEIRLQHVKVQQEKGIELIPIGDFTYY 67

Query: 268  DQVLDTTAMLGAVPDRYSWTGGEINLSTYFSMARGNATVPAMEMTKWFDTNYHFIVPELG 447
            D VLDT  MLG +P R+S     +++  YF+MARG+    A EMTKWF+TNYH+IVPE  
Sbjct: 68   DHVLDTAYMLGFIPSRFSEFTSYLDV--YFAMARGSKDHVASEMTKWFNTNYHYIVPEYE 125

Query: 448  PDTKFSYSSHKAINEYKEAKA-LGVDTVPVLVGPVSYLLLSKAAKGVEKSFXXXXXXXXX 624
               + S   ++ +  Y+EAK  LGVD  PV++GP ++L L+K     ++ F         
Sbjct: 126  EGLQISLKDNRPLRLYEEAKQELGVDGKPVILGPYTFLKLAKGY--TQEQFATILKQLVA 183

Query: 625  XXVYKEVIAELKAAGASWIQFDEPTLVKDPESHQLAAFSAAYTELESTLSGLNVLVETYF 804
               Y ++++EL AAGA  IQ DEP +       ++      Y  +   +    +L++TYF
Sbjct: 184  P--YVQLLSELHAAGAQIIQVDEP-IFASLTKEEVQQAKEIYEAIRKEVPNATLLLQTYF 240

Query: 805  ADVPAESYKTLTSLSSVTAYGFDLERGTK--TLELVKSGFPAGKYLFAGVVDGRYIWADD 978
              V  E+Y+ + +   V++ G D   G +     + K GFPA K L  G +DGR IW  D
Sbjct: 241  DSVE-ENYEEIITFP-VSSIGLDFVHGKEGNLNAISKYGFPADKTLAVGCIDGRNIWRAD 298

Query: 979  LAASLATLQSLEAIVGKDKLVVSTSCSLMHTAVDLVNETKLDDEIKSWLAFAAQKVVEVN 1158
            L   L    +L+  V    L+V  SCSL+HT +D   ET L  E+   LAFA QK+ E+ 
Sbjct: 299  LDEVLTLFTTLQKQVQTKDLIVQPSCSLLHTPIDKTEETHLSTELFDALAFANQKLEELV 358

Query: 1159 ALAKALAGQKDEXXXXXXXXXXXXXXXXXXVTN--EEVQKAATALKGSDHRRATTVSARL 1332
             +  AL    +                        E+V+ A TALK  D  R      R 
Sbjct: 359  LIHSALTQGTESISNELETYRNVHHTIRSSAARNREDVKAARTALKEEDFSRPLPFEKRY 418

Query: 1333 DAQQKKLNLPVLPTTTIGSFPQTVELRRVRREYKAKKISEEEYTNAIKEEISKVVKIQEE 1512
            + QQ  L LP+LPTTTIGSFPQT E+R+ R+E++   IS E+Y   I++E  K ++ QEE
Sbjct: 419  ELQQVALKLPLLPTTTIGSFPQTTEVRQTRKEWRNGIISNEQYEQFIEKETEKWIRYQEE 478

Query: 1513 LDIDVLVHGEPERNDMVEYFGEQLSGFTFTANGWVQSYGSRCVKPPIIYGDVSRPNPMTV 1692
            + +DVLVHGE ER DMVEYFGE+L+GF+FT NGWVQSYGSRCVKPP+IYGDV+  N MT+
Sbjct: 479  IGLDVLVHGEFERTDMVEYFGERLAGFSFTKNGWVQSYGSRCVKPPVIYGDVAFINGMTI 538

Query: 1693 FWSKMAQSMTARPMKGMLTGPVTILNWSFVRNDQPRFETCYQIALAIKKEVEDLEAGGIQ 1872
              +  AQS+T + +KGMLTGPVTILNWSFVRND PR E  YQIALA++ E+E LE+ GI+
Sbjct: 539  KETVYAQSLTEKVVKGMLTGPVTILNWSFVRNDIPRKEVSYQIALALRHEIELLESSGIR 598

Query: 1873 VIQIDEAALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDTTQIHTHMCYSNFNDIIQSI 2052
            VIQ+DE ALREG+PL++ +   Y+ WAV SF +    V + TQIHTHMCYSNF DI+ +I
Sbjct: 599  VIQVDEPALREGMPLKEKDWDAYITWAVQSFLLATSSVANETQIHTHMCYSNFEDIVDAI 658

Query: 2053 INMDADVITIENSRSDEKLLSVFREGVVYGAGIGPGVYDIHSPRIPSKEEIADRVNKMLA 2232
              +DADVI+IE SRS  + +   +    Y  GIG GVYDIHSPR+PSK+E+   V + L 
Sbjct: 659  RALDADVISIETSRSHGEFIDTLKH-TTYEKGIGLGVYDIHSPRVPSKDEMYKIVEQSLQ 717

Query: 2233 VLDTNILWVNPDCGLKTRKYAEVKPALTNMVEAAKQIRAEL 2355
            V D    W+NPDCGLKTR+  EV PAL +MV+AAK  R+ L
Sbjct: 718  VCDPKYFWINPDCGLKTRRTEEVIPALEHMVQAAKDARSLL 758

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>Q725Q3:METE_DESVH 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase|
            - Desulfovibrio vulgaris (strain Hildenborough / ATCC
            29579 / NCIMB 8303)
          Length = 785

 Score =  615 bits (1586), Expect = e-175
 Identities = 343/786 (43%), Positives = 468/786 (59%), Gaps = 25/786 (3%)
 Frame = +1

Query: 73   MASHIVGYPRMGPKRELKFALESFWDGKSSAEDLEKVATDLRASIWKQMAGAGIKYIPSN 252
            M +H +G+PR+G  RELK A+E +W G+ S   LE  A  LRA  W     AGI  +P  
Sbjct: 1    MRTHNLGFPRIGAGRELKKAVEGYWKGRVSRHALEGEAARLRACHWAMQRDAGIDVVPVG 60

Query: 253  TFAYYDQVLDTTAMLGAVPDRYSWTGGEIN-------LSTYFSMARGNA---TVPAMEMT 402
             FA YD +LD T MLGA+P R+S +G   +       +   F MARG A    V  +EMT
Sbjct: 61   DFALYDHMLDLTLMLGAIPPRFSPSGAAASPAGTGQDIDLMFRMARGEAGLSPVAPLEMT 120

Query: 403  KWFDTNYHFIVPELGPDTKFSYSSHKAINEYKEAKALGVDTVPVLVGPVSYLLLSKAAKG 582
            KWFDTNYH++VPEL  DT F+  +   + + +EA+  G     VL GP+++L L+++  G
Sbjct: 121  KWFDTNYHYLVPELDADTAFAPDASPLVAQLREAQDAGFTPKAVLPGPLTWLWLARSVDG 180

Query: 583  VEKSFXXXXXXXXXXXVYKEVIAELKAA-------GASWIQFDEPTLVKDPESHQLAAFS 741
             ++             + +E+ +    A       G   +Q DEP L  D        F 
Sbjct: 181  SDRFALLPALCDAYATLLRELTSACPPACPRGYSSGGLMVQLDEPVLALDLPQTVRDLFP 240

Query: 742  AAYTELESTLSGLNVLVETYFADVPAESYKTLTSLSSVTAYGFDLERGTKTLELVKSGFP 921
            A YT L + +    ++V +YFA   A++     +L  V     DL RG   L+       
Sbjct: 241  AVYTRLRAAVPDATLMVASYFAPC-ADNLPVALNLP-VDVLHLDLVRGRDDLDAALQVLG 298

Query: 922  AGK-----YLFAGVVDGRYIWADDLAASLATLQSLEAIVGKDKLVVSTSCSLMHTAVDLV 1086
            AG+      L  GVVDGR +W  D+ A++  ++     +G+D++ V+ SCSL+H  VDL 
Sbjct: 299  AGEGTPGLALSLGVVDGRNVWCADIDAAVNLVRRAADSLGEDRVWVAPSCSLLHCPVDLG 358

Query: 1087 NETKLDDEIKSWLAFAAQKVVEVNALAKALAG---QKDEXXXXXXXXXXXXXXXXXXVTN 1257
            +E +LD E+  WLAFA QK  EV  +A+ + G                         + +
Sbjct: 359  SERELDPEVARWLAFARQKCAEVRLVAEVVRGVYGPSTAASLEANREVRRQRAVSPRIHD 418

Query: 1258 EEVQKAATALKGSDHRRATTVSARLDAQQKKLNLPVLPTTTIGSFPQTVELRRVRREYKA 1437
              V     A+      R +  + R+ AQ+  L+LP LPTTTIGSFPQT ++R  RR  + 
Sbjct: 419  PAVASRLAAVTSDMEHRTSPYAERIVAQRAALHLPTLPTTTIGSFPQTPDIRAARRALRD 478

Query: 1438 KKISEEEYTNAIKEEISKVVKIQEELDIDVLVHGEPERNDMVEYFGEQLSGFTFTANGWV 1617
              ++++ Y  A+++ ++ +V+ QE L +DVLVHGEPERNDMVEYFG  L GF  T++GWV
Sbjct: 479  GSLTQDAYEAAMRDALAMMVREQEALGLDVLVHGEPERNDMVEYFGGLLQGFCITSDGWV 538

Query: 1618 QSYGSRCVKPPIIYGDVSRPNPMTVFWSKMAQSMTARPMKGMLTGPVTILNWSFVRNDQP 1797
            QSYG+RCVKPP++YGDVSRP PMTV WS  A+S+TARPMK MLTGPVTI  WSFVR+D  
Sbjct: 539  QSYGTRCVKPPLLYGDVSRPEPMTVAWSAYARSLTARPMKAMLTGPVTIACWSFVRDDIS 598

Query: 1798 RFETCYQIALAIKKEVEDLEAGGIQVIQIDEAALREGLPLRKSEHAFYLDWAVHSFRITN 1977
            R     Q+ALA++ EV DLE+ G+ V+Q+DE ALREGLPLR++    YLD AV +FR+  
Sbjct: 599  RETVLRQLALALRDEVADLESAGLAVVQVDEPALREGLPLRRAAQEAYLDAAVRAFRLAT 658

Query: 1978 CGVQDTTQIHTHMCYSNFNDIIQSIINMDADVITIENSRSDEKLLSVFREGVVYGAGIGP 2157
             GV D TQ+HTHMCY +F+DII  I  MDADVI++E SRS  +LL VF     Y   +GP
Sbjct: 659  SGVADATQLHTHMCYCDFHDIIDRIAGMDADVISLEASRSRMELLDVFATH-GYPNEVGP 717

Query: 2158 GVYDIHSPRIPSKEEIADRVNKMLAVLDTNILWVNPDCGLKTRKYAEVKPALTNMVEAAK 2337
            GVYDIHSPR+PS +E+   + +  AVL  + LWVNPDCGLKTR++ E + AL NMVEAA+
Sbjct: 718  GVYDIHSPRVPSVDEMEALLLRAAAVLPVDRLWVNPDCGLKTREWPETRAALANMVEAAR 777

Query: 2338 QIRAEL 2355
            ++RA L
Sbjct: 778  RVRARL 783

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>Q89B24:METE_BUCBP 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase|
            - Buchnera aphidicola subsp. Baizongia pistaciae
          Length = 756

 Score =  615 bits (1586), Expect = e-175
 Identities = 345/765 (45%), Positives = 455/765 (59%), Gaps = 6/765 (0%)
 Frame = +1

Query: 79   SHIVGYPRMGPKRELKFALESFWDGKSSAEDLEKVATDLRASIWKQMAGAGIKYIPSNTF 258
            +H +G+PR+G  RELK A E +W  K S E+L  V   LR   W+Q    GI YIP   F
Sbjct: 4    NHTLGFPRIGLFRELKVAQEKYWSRKISKEELFSVGKTLRVRHWQQQKELGINYIPVGDF 63

Query: 259  AYYDQVLDTTAMLGAVPDRYSWTGGEINLSTYFSMARG----NATVPAMEMTKWFDTNYH 426
            ++YD VL T+ +LG +P R+      + L T F +ARG     A+V A EMTKWF+TNYH
Sbjct: 64   SWYDHVLGTSMLLGNIPKRHKNGNDLVTLDTLFRVARGVAPTGASVSASEMTKWFNTNYH 123

Query: 427  FIVPELGPDTKFSYSSHKAINEYKEAKALGVDTVPVLVGPVSYLLLSKAAKGVEKSFXXX 606
            +IVPE    ++F +S  + ++E  EA  LG    PV++GP++YL L K  KG  K F   
Sbjct: 124  YIVPEFSIKSEFCFSWRQILDEIDEALLLGHQVKPVILGPLTYLWLGKV-KG--KKFDRL 180

Query: 607  XXXXXXXXVYKEVIAELKAAGASWIQFDEPTLVKDPESHQLAAFSAAYTELESTLSGLN- 783
                    VYK +++E+     SW+Q DEP L  +       AF  AY     +L G N 
Sbjct: 181  NLLKEILPVYKYLLSEINDRNISWVQIDEPILTLELPEKWKNAFRFAY----QSLYGYNS 236

Query: 784  VLVETYFADVPAESYKTLTSLSSVTAYGFDLERGTKTLELVKSGFPAGKYLFAGVVDGRY 963
            +L+ TYF  V   ++  +  L  +     DL  G   L  + S  P    +  G+++G+ 
Sbjct: 237  LLLTTYFGSVQ-HNFSLICELP-IQGVHLDLVHGKYDLVFLNSFIPEKWLISLGIINGKN 294

Query: 964  IWADDLAASLATLQSLEAIVGKDKLVVSTSCSLMHTAVDLVNETKLDDEIKSWLAFAAQK 1143
            IW  DL      LQ    +  +  L + TSCSL+H  +DL  E K+  E++SW +FA QK
Sbjct: 295  IWKADLVMWFKRLQLFSKL--RHSLWIGTSCSLLHVPIDLKLENKISSEVRSWFSFALQK 352

Query: 1144 VVEVNALAKALAGQKDEXXXXXXXXXXXXXXXXXXVT-NEEVQKAATALKGSDHRRATTV 1320
              E+  L  AL                        +  N +V++   ++  +D +R    
Sbjct: 353  CQELTLLRDALNNSNTVTEDIRVWSQPIHSRKKSAIVHNVDVKERLKSITSNDFKRNNVF 412

Query: 1321 SARLDAQQKKLNLPVLPTTTIGSFPQTVELRRVRREYKAKKISEEEYTNAIKEEISKVVK 1500
            S R   Q K L LP+LPTTTIGSFPQT ++R+ R ++K   I+ ++Y   I + I   + 
Sbjct: 413  SVRKQKQHKNLKLPILPTTTIGSFPQTADIRKARFDFKKGNINHDQYNTFISKHIQNAIL 472

Query: 1501 IQEELDIDVLVHGEPERNDMVEYFGEQLSGFTFTANGWVQSYGSRCVKPPIIYGDVSRPN 1680
             QE+L IDVLVHGE ERNDMVEYFGE L+GF FT  GWVQSYGSRCVKPPII GDVSR  
Sbjct: 473  KQEKLGIDVLVHGEFERNDMVEYFGEHLNGFVFTEFGWVQSYGSRCVKPPIIIGDVSRSK 532

Query: 1681 PMTVFWSKMAQSMTARPMKGMLTGPVTILNWSFVRNDQPRFETCYQIALAIKKEVEDLEA 1860
            P+++ W K AQ++T++P+KGMLTGPVTIL WSFVR D  +     QIALA++ EV DLE 
Sbjct: 533  PISLDWIKYAQTLTSKPVKGMLTGPVTILLWSFVREDLSKKIISRQIALALRDEVLDLEQ 592

Query: 1861 GGIQVIQIDEAALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDTTQIHTHMCYSNFNDI 2040
             G+++IQIDE ALREGLPLR S    YL WAV SF++++ GV D TQIHTHMCY  FNDI
Sbjct: 593  SGVKIIQIDEPALREGLPLRLSLRNEYLSWAVDSFKLSSSGVCDETQIHTHMCYCEFNDI 652

Query: 2041 IQSIINMDADVITIENSRSDEKLLSVFREGVVYGAGIGPGVYDIHSPRIPSKEEIADRVN 2220
            + +I+ +DADVITIE SRSD +LL  F+E   Y   IGPGVYDIHSP IPS E I   + 
Sbjct: 653  MNAIVLLDADVITIETSRSDMELLEFFKE-FKYPNDIGPGVYDIHSPNIPSIEWIMTLLR 711

Query: 2221 KMLAVLDTNILWVNPDCGLKTRKYAEVKPALTNMVEAAKQIRAEL 2355
            + +  +    LWVNPDCGLKTR + E   +L NMV AAK +R +L
Sbjct: 712  QAMHYIPVKRLWVNPDCGLKTRTWDETYYSLENMVRAAKILRKKL 756

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>Q819H7:METE_BACCR 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase|
            - Bacillus cereus (strain ATCC 14579 / DSM 31)
          Length = 762

 Score =  613 bits (1581), Expect = e-174
 Identities = 347/761 (45%), Positives = 459/761 (60%), Gaps = 5/761 (0%)
 Frame = +1

Query: 88   VGYPRMGPKRELKFALESFWDGKSSAEDLEKVATDLRASIWKQMAGAGIKYIPSNTFAYY 267
            +GYPR+G +RE K  LE+FW  K   E       ++R    K     GI+ IP   F YY
Sbjct: 8    LGYPRIGLQREWKKTLEAFWSNKIDEEQFLTTMKEIRLQHVKVQQEKGIELIPIGDFTYY 67

Query: 268  DQVLDTTAMLGAVPDRYSWTGGEINLSTYFSMARGNATVPAMEMTKWFDTNYHFIVPELG 447
            D VLDT  MLG +P R+S     +++  YF+MARG+    A EMTKWF+TNYH+IVPE  
Sbjct: 68   DHVLDTAYMLGFIPSRFSEFTSYLDV--YFAMARGSKDHVASEMTKWFNTNYHYIVPEYE 125

Query: 448  PDTKFSYSSHKAINEYKEAKA-LGVDTVPVLVGPVSYLLLSKAAKGVEKSFXXXXXXXXX 624
               + S   ++ +  Y+EAK  LGVD  PV++GP ++L L+K     ++ F         
Sbjct: 126  EGLQISLKDNRPLRLYEEAKQELGVDGKPVILGPYTFLKLAKGY--TQEQFPTILKQLVA 183

Query: 625  XXVYKEVIAELKAAGASWIQFDEPTLVKDPESHQLAAFSAAYTELESTLSGLNVLVETYF 804
               Y ++++EL AAGA  IQ DEP      +     A    Y  +   +    +L++TYF
Sbjct: 184  P--YVQLLSELHAAGAPAIQVDEPIFASLTKKEVQQA-KEIYEAIRKEVPNATLLLQTYF 240

Query: 805  ADVPAESYKTLTSLSSVTAYGFDLERGTK--TLELVKSGFPAGKYLFAGVVDGRYIWADD 978
              V  E+Y+ + +   V+  G D   G +     + K GFPA K L  G +DGR IW  D
Sbjct: 241  DSVE-ENYEEIITFP-VSGIGLDFIHGKEGNLNAISKYGFPADKTLAVGCIDGRNIWRAD 298

Query: 979  LAASLATLQSLEAIVGKDKLVVSTSCSLMHTAVDLVNETKLDDEIKSWLAFAAQKVVEVN 1158
            L   L    +L+  V    ++V  SCSL+HT +D   ET L  E+   LAFA QK+ E+ 
Sbjct: 299  LDEVLELFTTLQKQVQTKDIIVQPSCSLLHTPIDKTEETHLSTELFDALAFANQKLEELV 358

Query: 1159 ALAKALAGQKDEXXXXXXXXXXXXXXXXXXVTN--EEVQKAATALKGSDHRRATTVSARL 1332
             +  AL    +                        E+V+ A TALK  D  R      R 
Sbjct: 359  LIHSALTQGTESISNELETYRNVHHTIRSSAARNREDVKAARTALKEEDFSRPLPFEKRY 418

Query: 1333 DAQQKKLNLPVLPTTTIGSFPQTVELRRVRREYKAKKISEEEYTNAIKEEISKVVKIQEE 1512
            + QQ  L LP+LPTTTIGSFPQT E+R+ R+E++   IS E+Y   I++E  K ++ QEE
Sbjct: 419  ELQQVALELPLLPTTTIGSFPQTTEVRQTRKEWRNGVISNEQYEQFIEKETEKWIRYQEE 478

Query: 1513 LDIDVLVHGEPERNDMVEYFGEQLSGFTFTANGWVQSYGSRCVKPPIIYGDVSRPNPMTV 1692
            + +DVLVHGE ER DMVEYFGE+L+GF+FT NGWVQSYGSRCVKPP+IYGDV+  N MT+
Sbjct: 479  IGLDVLVHGEFERTDMVEYFGERLAGFSFTKNGWVQSYGSRCVKPPVIYGDVAFINGMTI 538

Query: 1693 FWSKMAQSMTARPMKGMLTGPVTILNWSFVRNDQPRFETCYQIALAIKKEVEDLEAGGIQ 1872
              +  AQS+T + +KGMLTGPVTILNWSFVRND PR E  YQIALA++ E+E LE+ GI+
Sbjct: 539  KETVYAQSLTEKVVKGMLTGPVTILNWSFVRNDIPRKEVSYQIALALRHEIELLESSGIR 598

Query: 1873 VIQIDEAALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDTTQIHTHMCYSNFNDIIQSI 2052
            VIQ+DE ALREG+PL++ +   Y+ WAV SF +    V + TQIHTHMCYSNF DI+ +I
Sbjct: 599  VIQVDEPALREGMPLKEKDWDAYITWAVQSFLLATSSVANETQIHTHMCYSNFEDIVDAI 658

Query: 2053 INMDADVITIENSRSDEKLLSVFREGVVYGAGIGPGVYDIHSPRIPSKEEIADRVNKMLA 2232
              +DADVI+IE SRS  + +   +    Y  GIG GVYDIHSPR+PSK+E+   V + L 
Sbjct: 659  RALDADVISIETSRSHGEFIDTLKH-TTYEKGIGLGVYDIHSPRVPSKDEMYKIVEQSLE 717

Query: 2233 VLDTNILWVNPDCGLKTRKYAEVKPALTNMVEAAKQIRAEL 2355
            V D    W+NPDCGLKTR+  EV PAL +MV+AAK  R+ L
Sbjct: 718  VCDPKYFWINPDCGLKTRRTEEVIPALEHMVQAAKDARSLL 758

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>Q9PN94:METE_CAMJE 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase|
            - Campylobacter jejuni
          Length = 754

 Score =  610 bits (1572), Expect = e-173
 Identities = 341/767 (44%), Positives = 470/767 (61%), Gaps = 6/767 (0%)
 Frame = +1

Query: 73   MASHIVGYPRMGPKRELKFALESFWDGKSSAEDLEKVATDLRASIWKQMAGAGIKYIPSN 252
            M + I+ YPR+G  RELKFA+E ++  +SS E+L K A DLR   W+++  AGI +IPSN
Sbjct: 1    MKNSIISYPRIGANRELKFAIEKYFKNQSSKEELLKSAKDLRIRHWQEIQKAGIDFIPSN 60

Query: 253  TFAYYDQVLDTTAMLGAVPDRYSWTGGEINLSTYFSMARG----NATVPAMEMTKWFDTN 420
             F+ YD VLD   +   V  +Y     +  L  YF+ +RG    N  V A+ M KWF+TN
Sbjct: 61   DFSLYDNVLDAAVLFNIVHTKYKNLNLDA-LDEYFAQSRGYQGENGDVTALAMKKWFNTN 119

Query: 421  YHFIVPELGPDTKFSYSSHKAINEYKEAKALGVDTVPVLVGPVSYLLLSKAAKGVEKSFX 600
            YH++VPE       + +  K   EY EAK LG+++ PVL+G   + L    A   EK+  
Sbjct: 120  YHYLVPECDNADIIALTGDKIFKEYLEAKELGIESKPVLIG--IFTLFKLIAFKDEKT-- 175

Query: 601  XXXXXXXXXXVYKEVIAELKAAGASWIQFDEPTLVKDPESHQLAAFSAAYTELESTLSGL 780
                       Y E+  +L     +W++ DEP LV D     +A F   Y EL +    L
Sbjct: 176  QKLAKEKLLNAYIELFDKLNELKVTWLELDEPYLVYDLSKEDIALFEEFYQELLNHKKDL 235

Query: 781  NVLVETYFADVPAESYKTLTSLSSVTAYGFDLERGTKTLELVKS-GFPAGKYLFAGVVDG 957
             +L+++YF D+  + Y  L   S   A G D   G ++L LV+  GF   K LF G+++G
Sbjct: 236  KILLQSYFGDL-RDIYPKLLE-SKFDALGLDFIEGKQSLALVQQYGFAKDKILFGGLING 293

Query: 958  RYIWADDLAASLATLQSLEAIVGKDKLVVSTSCSLMHTAVDLVNETKLDDEIKSWLAFAA 1137
            + I+A+D A SL  ++ L+       ++++TSCSL+H       E+KLD       AFA 
Sbjct: 294  KNIYANDYAKSLKLIKELQKYT--QNIILNTSCSLLHVPYSTEFESKLDSSYLKLFAFAK 351

Query: 1138 QKVVEVNALAKALAGQKDEXXXXXXXXXXXXXXXXXXVTNEEVQKAATALKGSDHRRATT 1317
            +K+ E+  L + L   ++                     +E+V+    ALK  D  R  +
Sbjct: 352  EKLQELKDLKEILNSSEENPLFRANQELFKNIPERL---DEKVKARLKALKKEDFTRTPS 408

Query: 1318 VSARLDAQQKKLNLPVLPTTTIGSFPQTVELRRVRREYKAKKISEEEYTNAIKEEISKVV 1497
               R   Q++ L LP+LPTTTIGSFPQ+ ++R  R  +K +KIS + YT   +++I + +
Sbjct: 409  FKERALIQKEFLKLPLLPTTTIGSFPQSADVRSNRLAFKQEKISAQNYTEFNQQKIKECI 468

Query: 1498 KIQEELDIDVLVHGEPERNDMVEYFGEQLSGFTFTANGWVQSYGSRCVKPPIIYGDVSRP 1677
            +IQEE+ +DVLVHGE ERNDMVEYFGE L GF FT NGWVQSYG+RCVKPP+I+GDVSR 
Sbjct: 469  QIQEEIGLDVLVHGEFERNDMVEYFGENLKGFLFTQNGWVQSYGTRCVKPPVIWGDVSRT 528

Query: 1678 NPMTVFWSKMAQSMTARPMKGMLTGPVTILNWSFVRNDQPRFETCYQIALAIKKEVEDLE 1857
             P+T+ WSK AQS++ + +KGMLTGPVTILNWSF R D    E+  QIALAI+ EV DLE
Sbjct: 529  KPITLAWSKFAQSLSQKIVKGMLTGPVTILNWSFPREDISLKESTEQIALAIRDEVLDLE 588

Query: 1858 AGGIQVIQIDEAALREGLPLRKSE-HAFYLDWAVHSFRITNCGVQDTTQIHTHMCYSNFN 2034
              GI++IQIDEAALRE LPLRKS+ H+ YLDWA+ +F + + GV+  TQIHTHMCYS F+
Sbjct: 589  NAGIKIIQIDEAALREKLPLRKSDWHSEYLDWAIPAFNLVHSGVKAKTQIHTHMCYSEFS 648

Query: 2035 DIIQSIINMDADVITIENSRSDEKLLSVFREGVVYGAGIGPGVYDIHSPRIPSKEEIADR 2214
            DI++ I  MDADVI+ E SRS+  LL   +  + +   +GPGVYDIHSPR+PS EE++  
Sbjct: 649  DILKEIDAMDADVISFEASRSNLSLLDTLK-AIRFKTEVGPGVYDIHSPRVPSVEELSLT 707

Query: 2215 VNKMLAVLDTNILWVNPDCGLKTRKYAEVKPALTNMVEAAKQIRAEL 2355
            + K+L  L    +W+NPDCGLKTR Y EV  +L N+V A ++IR +L
Sbjct: 708  IEKILNKLPKEQIWINPDCGLKTRAYEEVITSLKNLVTATQKIREQL 754

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>Q88X63:METE_LACPL 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase|
            - Lactobacillus plantarum
          Length = 768

 Score =  608 bits (1567), Expect = e-173
 Identities = 335/762 (43%), Positives = 457/762 (59%), Gaps = 6/762 (0%)
 Frame = +1

Query: 88   VGYPRMGPKRELKFALESFWDGKSSAEDLEKVATDLRASIWKQMAGAGIKYIPSNTFAYY 267
            +GYPR+G  RE K  LE FW G+         A  LR +  K+    G+ YIP    + Y
Sbjct: 8    LGYPRLGEHREWKHLLEHFWKGQLDNVTFHATAKKLRLANLKKQRDLGVDYIPVADNSDY 67

Query: 268  DQVLDTTAMLGAVPDRYSWTGGEINLSTYFSMARGNATVPAMEMTKWFDTNYHFIVPELG 447
            D VLDT     A+P R+     +++L  Y+++ARG  T  A EMTKWF+ NYH+IVPE  
Sbjct: 68   DHVLDTLVAFNAIPSRFGHFDHQLDLPDYYAIARGTDTAVAAEMTKWFNINYHYIVPEF- 126

Query: 448  PDTKFSYSSHKAINEYKEAK-ALGVDTVPVLVGPVSYLLLSKAAKGVEKSFXXXXXXXXX 624
             D  F    ++ +  Y+EAK  LG+D  PV++GP+S+L L K                  
Sbjct: 127  DDVSFKLLDNRWLRYYQEAKQELGIDGKPVILGPISFLKLGKRHGQYLDDAAVNELLPQL 186

Query: 625  XXVYKEVIAELKAAGASWIQFDEPTLVKDPESHQLAAFSAAYTELESTLSGLNVLVETYF 804
              +Y++V  EL  AGA WIQ DEPTLVK     +LA +  A   L + +  L + ++TYF
Sbjct: 187  LPLYQQVFEELATAGAKWIQLDEPTLVKTTTVAELAPYQTALEHLHAAVPSLKIELQTYF 246

Query: 805  ADVPAESYKTLTSLSSVTAYGFDL--ERGTKTLELVKSGFPAGKYLFAGVVDGRYIWADD 978
              +  + Y  + +   + A G DL  + G     LV  GFP  K L AG++DG  +WA D
Sbjct: 247  DSL--DQYDKIVTW-PIQALGLDLVHDHGENLAHLVDHGFPTDKILAAGIIDGHNVWASD 303

Query: 979  LAASLATLQSLEAIVGKDKLVVSTSCSLMHTAVDLVNETKLDDEIKSWLAFAAQKVVEVN 1158
            L A LA +Q L  IV  D+L +  + SL+H  +   NETK D  +   LAFA QK+ E++
Sbjct: 304  LQAKLALVQQLRQIVTDDQLWLQPANSLLHVPITTKNETKADPVLLGGLAFADQKLAELH 363

Query: 1159 ALAKALAGQ---KDEXXXXXXXXXXXXXXXXXXVTNEEVQKAATALKGSDHRRATTVSAR 1329
             L  A A Q     +                    N+ V+ A   L      R    + R
Sbjct: 364  TLTVA-ANQGVAAVQAVFDHNQANLTALNQSSHRNNQSVRAAEAQLSNQKFERQAPFATR 422

Query: 1330 LDAQQKKLNLPVLPTTTIGSFPQTVELRRVRREYKAKKISEEEYTNAIKEEISKVVKIQE 1509
            +  Q  +L+LP+LPTTTIGSFPQ+ ++R  R  ++   +++ +Y   +  E  + +K+QE
Sbjct: 423  IKLQHDRLHLPLLPTTTIGSFPQSAQVRAKRAAWRKGNLTDADYQAFLHAETKRWIKLQE 482

Query: 1510 ELDIDVLVHGEPERNDMVEYFGEQLSGFTFTANGWVQSYGSRCVKPPIIYGDVSRPNPMT 1689
            +L +DVLVHGE ER DMVEYFG++L+GF  T NGWVQSYGSR V+PP+I+GDV+   P+T
Sbjct: 483  DLGLDVLVHGEFERTDMVEYFGQKLTGFYATQNGWVQSYGSRGVRPPVIFGDVAYTEPIT 542

Query: 1690 VFWSKMAQSMTARPMKGMLTGPVTILNWSFVRNDQPRFETCYQIALAIKKEVEDLEAGGI 1869
            V  S  AQS+T +P+KGMLT P+TI+NWSFVR+D PR +   QIALA+++EV++LE  GI
Sbjct: 543  VAESVYAQSLTDQPVKGMLTAPLTIINWSFVRDDIPRAQVQNQIALALRQEVQNLEKAGI 602

Query: 1870 QVIQIDEAALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDTTQIHTHMCYSNFNDIIQS 2049
            ++IQ+DE ALREGLPL++     YLD AV+SF+IT  GVQ+ TQIHTHMCYSNF DII +
Sbjct: 603  KIIQVDEPALREGLPLKQRHWQAYLDEAVYSFKITTTGVQNDTQIHTHMCYSNFADIINT 662

Query: 2050 IINMDADVITIENSRSDEKLLSVFREGVVYGAGIGPGVYDIHSPRIPSKEEIADRVNKML 2229
            I  +DADVI+IE SRS  +++S F E   Y   IG GVYDIHSPR+PS  EI   + + L
Sbjct: 663  IKALDADVISIETSRSHGEIISAF-EQTGYDQEIGLGVYDIHSPRVPSVAEIEANIQRAL 721

Query: 2230 AVLDTNILWVNPDCGLKTRKYAEVKPALTNMVEAAKQIRAEL 2355
             V+D    W+NPDCGLKTR+ +E   AL NM+ A   I+A+L
Sbjct: 722  RVIDARQFWINPDCGLKTRQESETLAALKNMIAARNAIQAQL 763

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>Q8CWX6:METE_STRMU 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase|
            - Streptococcus mutans
          Length = 745

 Score =  600 bits (1547), Expect = e-170
 Identities = 345/759 (45%), Positives = 459/759 (60%), Gaps = 3/759 (0%)
 Frame = +1

Query: 88   VGYPRMGPKRELKFALESFWDGKSSAEDLEKVATDLRASIWKQMAGAGIKYIPSNTFAYY 267
            +GYPR+G  RE K  +E++W GK S  DL   A +LR    K+   AG+  IP   F+ Y
Sbjct: 7    LGYPRLGENREWKKLIEAYWAGKVSKNDLFAGAKELRLDFLKKQLNAGLDLIPVGDFSLY 66

Query: 268  DQVLDTTAMLGAVPDRYSWTGGEINLSTYFSMARGNATVPAMEMTKWFDTNYHFIVPELG 447
            D +LD +     +P R++    +I+L  YF++ARGN    A  M KWF+TNYH+IVPE  
Sbjct: 67   DHILDLSVQFNIIPKRFAKEPIDIDL--YFAIARGNKENVASSMKKWFNTNYHYIVPEWS 124

Query: 448  PDTKFSYSSHKAINEYKEAK-ALGVDTVPVLVGPVSYLLLSKAAKGVEKSFXXXXXXXXX 624
                   ++++ ++ Y EA+  +G    PV+ GP++Y+ LS    GVE            
Sbjct: 125  KQRP-KLNNNRLLDLYLEAREVVGDKAKPVITGPITYVALST---GVED---FTAAVKSL 177

Query: 625  XXVYKEVIAELKAAGASWIQFDEPTLVKDPESHQLAAFSAAYTELESTLSGLNVLVETYF 804
              +YK+V  EL  AGAS+IQ DEP  V D     L A  A Y      +     + +TYF
Sbjct: 178  LPLYKQVFTELVKAGASYIQVDEPIFVTDEGKDYLQAAKAVYAYFAKEVPDAKFIFQTYF 237

Query: 805  ADVPAESYKTLTSLSSVTAYGFDLERGTK-TLELVKSGFPAGKYLFAGVVDGRYIWADDL 981
              +       + S   V A+G D   G +  LE +K+G   GK +FAGV+DGR IW+ D 
Sbjct: 238  EGLIDSQ---VLSQLPVDAFGLDFVYGLEENLEAIKTGAFKGKEIFAGVIDGRNIWSSDF 294

Query: 982  AASLATLQSLEAIVGKDKLVVSTSCSLMHTAVDLVNETKLDDEIKSWLAFAAQKVVEVNA 1161
              + A L+++E       L +  SCSL+H  V   NET LD  +++ LAFA +K+ EV  
Sbjct: 295  VKTSALLETIEE--QSAALTIQPSCSLLHVPVTTKNETDLDPVLRNGLAFADEKLTEVKR 352

Query: 1162 LAKALAGQKDEXXXXXXXXXXXXXXXXXX-VTNEEVQKAATALKGSDHRRATTVSARLDA 1338
            LA+ L G++D                    V  E++ + AT       +R +  + R D 
Sbjct: 353  LAEHLDGREDPAYDLHIAHFDALQAADFRNVKLEDLSRVAT-------KRPSDFAKRRDI 405

Query: 1339 QQKKLNLPVLPTTTIGSFPQTVELRRVRREYKAKKISEEEYTNAIKEEISKVVKIQEELD 1518
            QQ+KL+LP+LPTTTIGSFPQ+ E+RR R  +K   IS+ EY   I+ EI + ++IQE+LD
Sbjct: 406  QQEKLHLPLLPTTTIGSFPQSREIRRTRLAWKRGDISDAEYKQFIQAEIERWIRIQEDLD 465

Query: 1519 IDVLVHGEPERNDMVEYFGEQLSGFTFTANGWVQSYGSRCVKPPIIYGDVSRPNPMTVFW 1698
            +DVLVHGE ER DMVE+FG++L+GFT T  GWVQSYGSR VKPPIIYGDV    P+TV  
Sbjct: 466  LDVLVHGEFERVDMVEFFGQKLAGFTTTKFGWVQSYGSRAVKPPIIYGDVQHLEPITVEE 525

Query: 1699 SKMAQSMTARPMKGMLTGPVTILNWSFVRNDQPRFETCYQIALAIKKEVEDLEAGGIQVI 1878
            +  AQS+T RP+KGMLTGP+TI NWSF R D PR +   QI LAIK E++ LE  GI +I
Sbjct: 526  TVYAQSLTDRPVKGMLTGPITITNWSFERTDIPRDQLFNQIGLAIKDEIKLLENAGIAII 585

Query: 1879 QIDEAALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDTTQIHTHMCYSNFNDIIQSIIN 2058
            Q+DEAALREGLPLRKS+   YLD AVH+F I    V+D TQIHTHMCYS F++II +I  
Sbjct: 586  QVDEAALREGLPLRKSKQKAYLDDAVHAFHIATSSVKDETQIHTHMCYSKFDEIIDAIRA 645

Query: 2059 MDADVITIENSRSDEKLLSVFREGVVYGAGIGPGVYDIHSPRIPSKEEIADRVNKMLAVL 2238
            +DADVI+IE SRS   ++  F E  VY  GIG GVYDIHSPR+P+KEE+   + + L  L
Sbjct: 646  LDADVISIETSRSHGDIIESF-ETAVYPLGIGLGVYDIHSPRVPTKEEVVANIERPLRQL 704

Query: 2239 DTNILWVNPDCGLKTRKYAEVKPALTNMVEAAKQIRAEL 2355
                 WVNPDCGLKTR+  E   AL  +V A K++R +L
Sbjct: 705  SPTQFWVNPDCGLKTRQEPETIAALKVLVAATKEVRQKL 743

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>Q8NRB3:METE_CORGL 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase|
            - Corynebacterium glutamicum (Brevibacterium flavum)
          Length = 745

 Score =  600 bits (1546), Expect = e-170
 Identities = 339/766 (44%), Positives = 456/766 (59%), Gaps = 6/766 (0%)
 Frame = +1

Query: 76   ASHIVGYPRMGPKRELKFALESFWDGKSSAEDLEKVATDLRASIWKQMAGAGIKYIPSNT 255
            +S + G PR+G KRELKFALE +W+G     +L + A  L  +    ++G  +  +P   
Sbjct: 6    SSTVAGLPRIGAKRELKFALEGYWNGSIEGRELAQTARQLVNTASDSLSG--LDSVPFAG 63

Query: 256  FAYYDQVLDTTAMLGAVPDRYSWTGGEIN------LSTYFSMARGNATVPAMEMTKWFDT 417
             +YYD +LDT A+LG +P+R+       N      +  YF  ARG  T+PA  MTKWFDT
Sbjct: 64   RSYYDAMLDTAAILGVLPERFDDIADHENDGLPLWIDRYFGAARGTETLPAQAMTKWFDT 123

Query: 418  NYHFIVPELGPDTKFSYSSHKAINEYKEAKALGVDTVPVLVGPVSYLLLSKAAKGVEKSF 597
            NYH++VPEL  DT+F   +   I + +  +  GV+  PVLVGP+++L L++   G     
Sbjct: 124  NYHYLVPELSADTRFVLDASALIEDLRCQQVRGVNARPVLVGPLTFLSLARTTDGSNP-- 181

Query: 598  XXXXXXXXXXXVYKEVIAELKAAGASWIQFDEPTLVKDPESHQLAAFSAAYTELESTLSG 777
                       VY+ +I   K+    W+Q DEP LV D     L    A YT L      
Sbjct: 182  --LDHLPALFEVYERLI---KSFDTEWVQIDEPALVTDVAPEVLEQVRAGYTTLAKRDG- 235

Query: 778  LNVLVETYFADVPAESYKTLTSLSSVTAYGFDLERGTKTLELVKSGFPAGKYLFAGVVDG 957
              V V TYF     ++  TL  +  + A G DL     T EL  + +   + L AG+VDG
Sbjct: 236  --VFVNTYFGSGD-QALNTLAGIG-LGAIGVDLVTHGVT-EL--AAWKGEELLVAGIVDG 288

Query: 958  RYIWADDLAASLATLQSLEAIVGKDKLVVSTSCSLMHTAVDLVNETKLDDEIKSWLAFAA 1137
            R IW  DL A+LA+L+ L A   +  + VSTSCSL+H    L  E  ++ E++ WLAF +
Sbjct: 289  RNIWRTDLCAALASLKRLAA---RGPIAVSTSCSLLHVPYTLEAEN-IEPEVRDWLAFGS 344

Query: 1138 QKVVEVNALAKALAGQKDEXXXXXXXXXXXXXXXXXXVTNEEVQKAATALKGSDHRRATT 1317
            +K+ EV  LA ALAG  D                    T+         L G   R   +
Sbjct: 345  EKITEVKLLADALAGNIDAAAFDAASAAIASRR-----TSPRTAPITQELPG---RSRGS 396

Query: 1318 VSARLDAQQKKLNLPVLPTTTIGSFPQTVELRRVRREYKAKKISEEEYTNAIKEEISKVV 1497
               R+  Q+K L LP LPTTTIGSFPQT  +R  R   + + I+ E+Y  A++EEI  V+
Sbjct: 397  FDTRVTLQEKSLELPALPTTTIGSFPQTPSIRSARARLRKESITLEQYEEAMREEIDLVI 456

Query: 1498 KIQEELDIDVLVHGEPERNDMVEYFGEQLSGFTFTANGWVQSYGSRCVKPPIIYGDVSRP 1677
              QEEL +DVLVHGEPERNDMV+YF E L GF  TANGWVQSYGSRCV+PP+++G+VSRP
Sbjct: 457  AKQEELGLDVLVHGEPERNDMVQYFSELLDGFLSTANGWVQSYGSRCVRPPVLFGNVSRP 516

Query: 1678 NPMTVFWSKMAQSMTARPMKGMLTGPVTILNWSFVRNDQPRFETCYQIALAIKKEVEDLE 1857
             PMTV W + AQS+T + +KGMLTGPVTIL WSFVR+DQP   T  Q+ALA++ E+ DL 
Sbjct: 517  APMTVKWFQYAQSLTQKHVKGMLTGPVTILAWSFVRDDQPLATTADQVALALRDEINDLI 576

Query: 1858 AGGIQVIQIDEAALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDTTQIHTHMCYSNFND 2037
              G ++IQ+DE A+RE LPLR  +   YL W+V SFR+   G  D  QIHTHMCYS FN+
Sbjct: 577  EAGAKIIQVDEPAIRELLPLRDVDKPAYLQWSVDSFRLATAGAPDDVQIHTHMCYSEFNE 636

Query: 2038 IIQSIINMDADVITIENSRSDEKLLSVFREGVVYGAGIGPGVYDIHSPRIPSKEEIADRV 2217
            +I S+I +DADV TIE +RSD ++L+  +    +  G+GPGV+DIHSPR+PS +E+   +
Sbjct: 637  VISSVIALDADVTTIEAARSDMQVLAALKSS-GFELGVGPGVWDIHSPRVPSAQEVDGLL 695

Query: 2218 NKMLAVLDTNILWVNPDCGLKTRKYAEVKPALTNMVEAAKQIRAEL 2355
               L  +D   LWVNPDCGLKTR + EV+ +L  +VE+AKQ R ++
Sbjct: 696  EAALQSVDPRQLWVNPDCGLKTRGWPEVEASLKVLVESAKQAREKI 741

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>O67606:METE_AQUAE 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase|
            - Aquifex aeolicus
          Length = 761

 Score =  594 bits (1532), Expect = e-169
 Identities = 340/776 (43%), Positives = 473/776 (60%), Gaps = 17/776 (2%)
 Frame = +1

Query: 79   SHIVGYPRMGPKRELKFALESFWDGKSSAEDLEKVATDL---RASIWKQMAGAGIKYIPS 249
            ++  G+P++G KRE K  LE++W GK S E+L K   +L   RA+++++     ++ IPS
Sbjct: 4    TYAFGFPKLGEKREFKRLLENYWKGKISQEELIKGMEELNLWRANLYRE----NVEIIPS 59

Query: 250  NTFAYYDQVLDTTAMLGAVPDRYSWTGGEINLSTYFSMARGNATVPAMEMTKWFDTNYHF 429
            N  +YYD +LDTT M+GA+P R+    G   L TYF MARG     A+E+TKWF+TNYH+
Sbjct: 60   NELSYYDFMLDTTVMVGAIPSRFGEYRG---LDTYFEMARGKN---ALELTKWFNTNYHY 113

Query: 430  IVPELGPDTKFSYSSHKAINEYKEAKALGVDTVPVLVGPVSYLLLSKAAKGVEKSFXXXX 609
            +VPEL  +  F    ++ + +YK  K  G++TVP ++G  ++L LSKA K VE+      
Sbjct: 114  LVPELEGEN-FKLLINRPLEDYKFFKEKGINTVPHVIGLFTFLKLSKAPKRVEEEGLPVI 172

Query: 610  XXXXXXX-------------VYKEVIAELKAAGASWIQFDEPTLVKDPESHQLAAFSAAY 750
                                VYKE++  LK  G + + F+EP LV D E +     +  Y
Sbjct: 173  ILEKLDTKERLEKFTKALLPVYKELLESLKNEGVNRVHFEEPALVTDLEDYDWEILNEIY 232

Query: 751  TELESTLSGLNVLVETYFADVPAESYKTLTSLSSVTAYGFDLERGTKTLELVKS-GFPAG 927
            +EL     G+++ + TY+  V    Y    +L  V A  FDL    + L+ +K  GFP  
Sbjct: 233  SELSKV--GVDLGILTYYDSV--SDYDKFVNLP-VKALHFDLVSNEENLKNIKEKGFPED 287

Query: 928  KYLFAGVVDGRYIWADDLAASLATLQSLEAIVGKDKLVVSTSCSLMHTAVDLVNETKLDD 1107
            K L AG+++GR  W  +L   +  L+ L  +     LVVS SC L H  V +  E +L +
Sbjct: 288  KELIAGIINGRQPWRANLREKVKLLEELLKVSAN--LVVSNSCPLYHLPVTVEPEDELPE 345

Query: 1108 EIKSWLAFAAQKVVEVNALAKALAGQKDEXXXXXXXXXXXXXXXXXXVTNEEVQKAATAL 1287
             +K  L+FA +K+ E+  + +AL G+++                     N EV++   +L
Sbjct: 346  GLKERLSFAKEKLREIRLIKEALEGKEEALREVESSEKVMTAVF---AQNPEVRRRLASL 402

Query: 1288 KGSDHRRATTVSARLDAQQKKLNLPVLPTTTIGSFPQTVELRRVRREYKAKKISEEEYTN 1467
               D +R      R   Q+  L LP+ PTTTIGSFPQT ++R++R  Y+  KISEEEY N
Sbjct: 403  SEKDFQRELPYKERDKIQRDILKLPLFPTTTIGSFPQTEDVRKMRTAYRTGKISEEEYKN 462

Query: 1468 AIKEEISKVVKIQEELDIDVLVHGEPERNDMVEYFGEQLSGFTFTANGWVQSYGSRCVKP 1647
             IK++I   +++QE++ +DVLVHGE ER+DMVEYF  +L G   T +GWV SYGSR  +P
Sbjct: 463  FIKQKIKYAIEVQEDIGLDVLVHGEFERSDMVEYFAIKLDGIATTKHGWVLSYGSRVYRP 522

Query: 1648 PIIYGDVSRPNPMTVFWSKMAQSMTARPMKGMLTGPVTILNWSFVRNDQPRFETCYQIAL 1827
            PIIYGDVSRP PMT+     AQS+T +P+KGMLTGPVTILNWS+ R D P+ E  YQIAL
Sbjct: 523  PIIYGDVSRPAPMTLEEITYAQSLTNKPVKGMLTGPVTILNWSYYREDVPKREIAYQIAL 582

Query: 1828 AIKKEVEDLEAGGIQVIQIDEAALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDTTQIH 2007
            A+  EV+DLE  GI+VIQIDE A REG PL+K +   Y DWAV +FR+ +   +  TQIH
Sbjct: 583  ALLDEVKDLENAGIKVIQIDEPAFREGAPLKKRDWPEYFDWAVKAFRLAS-RAKPETQIH 641

Query: 2008 THMCYSNFNDIIQSIINMDADVITIENSRSDEKLLSVFREGVVYGAGIGPGVYDIHSPRI 2187
            THMCYS FN+II+ I  MD DVI+IE SRS  +++ VF +   +   IG GVYDIHSP I
Sbjct: 642  THMCYSEFNEIIEYIYQMDFDVISIEASRSKGEIIEVFEKFKGWDRQIGIGVYDIHSPAI 701

Query: 2188 PSKEEIADRVNKMLAVLDTNILWVNPDCGLKTRKYAEVKPALTNMVEAAKQIRAEL 2355
            P+KEE+   + + + VL   +LWVNPDCGLKTR++ EV PAL NMV+ AK++R E+
Sbjct: 702  PTKEEMKAIMLRAMKVLPKELLWVNPDCGLKTRRWEEVIPALRNMVDMAKELREEV 757

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>P80877:METE_BACSU 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase|
            - Bacillus subtilis
          Length = 762

 Score =  593 bits (1528), Expect = e-168
 Identities = 337/765 (44%), Positives = 455/765 (59%), Gaps = 10/765 (1%)
 Frame = +1

Query: 88   VGYPRMGPKRELKFALESFWDGKSSAEDLEKVATDLRASIWKQMAGAGIKYIPSNTFAYY 267
            +G+PR+   RE K ALE++W G +  +   K   +L  S  K      I  +P + F  Y
Sbjct: 9    LGFPRIDLNREWKKALEAYWKGSTDKDTFLKQIDELFLSAVKTQIDQQIDVVPVSDFTQY 68

Query: 268  DQVLDTTAMLGAVPDRYSWTGGEINLSTYFSMARGNATVPAMEMTKWFDTNYHFIVPELG 447
            D VLDT      +P R+       +  TYF++ARG     + EMTKWF+TNYH+IVPE  
Sbjct: 69   DHVLDTAVSFNWIPKRFRHLTDATD--TYFAIARGIKDAVSSEMTKWFNTNYHYIVPEYD 126

Query: 448  PDTKFSYSSHKAINEYKEAKA-LGVDTVPVLVGPVSYLLLSKA-----AKGVEKSFXXXX 609
               +F  + +K + +Y+  K   GV+T PV+VGP +++ L+K      AK ++K      
Sbjct: 127  ESIEFRLTRNKQLEDYRRIKQEYGVETKPVIVGPYTFVTLAKGYEPSEAKAIQKRLVP-- 184

Query: 610  XXXXXXXVYKEVIAELKAAGASWIQFDEPTLVKDPESHQLAAFSAAYTELESTLSGLNVL 789
                   +Y +++ EL+  G  W+Q DEP LV    S  +      +  + S LS LNVL
Sbjct: 185  -------LYVQLLKELEEEGVKWVQIDEPALVT-ASSEDVRGAKELFESITSELSSLNVL 236

Query: 790  VETYFADVPAESYKTLTSLSSVTAYGFDL--ERGTKTLELVKSGFPAGKYLFAGVVDGRY 963
            ++TYF  V A  Y+ L S   V   G D   ++G    +L   GFP  K L AGV+DGR 
Sbjct: 237  LQTYFDSVDA--YEELISYP-VQGIGLDFVHDKGRNLEQLKTHGFPTDKVLAAGVIDGRN 293

Query: 964  IWADDLAASLATLQSLEAIVGKDKLVVSTSCSLMHTAVDLVNETKLDDEIKSWLAFAAQK 1143
            IW  DL  SL  +  + +I   D+L +  S SL+   V    +  L+ ++ + L++A +K
Sbjct: 294  IWKADLEESLDAVLDVLSIAKVDELWIQPSSSLLDVPVAKHPDEHLEKDLLNGLSYAKEK 353

Query: 1144 VVEVNALAKALAGQKDEXXXXXXXXXXXXXXXXXXVT--NEEVQKAATALKGSDHRRATT 1317
            + E+ AL + L   K                     T  N E +K    L   D +R   
Sbjct: 354  LAELTALKEGLVSGKAAISEEIQQAKADIQALKQFATGANSEQKKELEQLTDKDFKRPIP 413

Query: 1318 VSARLDAQQKKLNLPVLPTTTIGSFPQTVELRRVRREYKAKKISEEEYTNAIKEEISKVV 1497
               RL  Q + L LP+LPTTTIGSFPQ+ E+RR R++++  + S+E+Y N I  E  + +
Sbjct: 414  FEERLALQNESLGLPLLPTTTIGSFPQSAEVRRARQKWRKAEWSDEQYQNFINAETKRWI 473

Query: 1498 KIQEELDIDVLVHGEPERNDMVEYFGEQLSGFTFTANGWVQSYGSRCVKPPIIYGDVSRP 1677
             IQEEL++DVLVHGE ER DMVEYFGE+L+GF FT   WVQSYGSRCV+PP+IYGDV   
Sbjct: 474  DIQEELELDVLVHGEFERTDMVEYFGEKLAGFAFTKYAWVQSYGSRCVRPPVIYGDVEFI 533

Query: 1678 NPMTVFWSKMAQSMTARPMKGMLTGPVTILNWSFVRNDQPRFETCYQIALAIKKEVEDLE 1857
             PMTV  +  AQS+T++ +KGMLTGPVTILNWSF RND  R E  +QI LA++KEV+ LE
Sbjct: 534  EPMTVKDTVYAQSLTSKHVKGMLTGPVTILNWSFPRNDISRKEIAFQIGLALRKEVKALE 593

Query: 1858 AGGIQVIQIDEAALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDTTQIHTHMCYSNFND 2037
              GIQ+IQ+DE ALREGLPL+  +   YL WA  +FR+T   V++ TQIHTHMCYSNF D
Sbjct: 594  DAGIQIIQVDEPALREGLPLKTRDWDEYLTWAAEAFRLTTSSVKNETQIHTHMCYSNFED 653

Query: 2038 IIQSIINMDADVITIENSRSDEKLLSVFREGVVYGAGIGPGVYDIHSPRIPSKEEIADRV 2217
            I+ +I ++DADVITIE+SRS    L  + +   Y  G+G GVYDIHSPR+PS EE+ + +
Sbjct: 654  IVDTINDLDADVITIEHSRSHGGFLD-YLKNHPYLKGLGLGVYDIHSPRVPSTEEMYNII 712

Query: 2218 NKMLAVLDTNILWVNPDCGLKTRKYAEVKPALTNMVEAAKQIRAE 2352
               LAV  T+  WVNPDCGLKTR+  E   AL NMVEAAKQ RA+
Sbjct: 713  VDALAVCPTDRFWVNPDCGLKTRQQEETVAALKNMVEAAKQARAQ 757

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>P65343:METE_STAAN 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase|
            - Staphylococcus aureus (strain N315)
          Length = 742

 Score =  576 bits (1484), Expect = e-163
 Identities = 339/757 (44%), Positives = 454/757 (59%), Gaps = 2/757 (0%)
 Frame = +1

Query: 88   VGYPRMGPKRELKFALESFWDGKSSAEDLEKVATDLRASIWKQMAGAGIKYIPSNTFAYY 267
            +G+PR+G KRE K A+ES+W  K S E+L++  TDL            +  IP   F+ Y
Sbjct: 9    LGFPRLGRKREWKKAIESYWAKKISKEELDQTLTDLHKENLLLQKYYHLDSIPVGDFSLY 68

Query: 268  DQVLDTTAMLGAVPDRYSWTGGEINLSTYFSMARGNATVPAMEMTKWFDTNYHFIVPELG 447
            D +LDT+ +   +P+R+   G  I+    F +ARGN    A  + KWF+TNYH+IVPE  
Sbjct: 69   DHILDTSLLFNIIPERFQ--GRTIDDDLLFDIARGNKDHVASALIKWFNTNYHYIVPEWD 126

Query: 448  PDTKFSYSSHKAINEYKEAKALGVDTVPVLVGPVSYLLLSKAAKGVEKSFXXXXXXXXXX 627
             + +   S +  ++ +K A++L V+  PV+VGP++++ LSK   G  ++F          
Sbjct: 127  -NVEPKVSRNVLLDRFKYAQSLNVNAHPVIVGPITFVKLSK---GGHQTFEEKVKTLLP- 181

Query: 628  XVYKEVIAELKAAGASWIQFDEPTLVKDPESHQLAAFSAAYTELESTLSGLNVLVETYFA 807
             +YKEV   L  AGA +IQ DEP LV D           AY   E       ++++TYF 
Sbjct: 182  -LYKEVFESLIDAGAEYIQVDEPILVTDDSESYENITREAYDYFEKAGVAKKLVIQTYFE 240

Query: 808  DVPAESYKTLTSLSSVTAYGFDL--ERGTKTLELVKSGFPAGKYLFAGVVDGRYIWADDL 981
                   K L+SL  V   G D   + G    ++    F   K L+AG++DGR +WA D+
Sbjct: 241  RA---HLKFLSSLP-VGGLGLDFVHDNGYNLKQIEAGDFDKSKTLYAGIIDGRNVWASDI 296

Query: 982  AASLATLQSLEAIVGKDKLVVSTSCSLMHTAVDLVNETKLDDEIKSWLAFAAQKVVEVNA 1161
             A    +  L  +   ++LV+  S SL+H  V L +ET LD  +   L+FA +K+ E++A
Sbjct: 297  EAKKVLIDKL--LAHTNELVIQPSSSLLHVPVSLDDET-LDTSVGEGLSFATEKLDELDA 353

Query: 1162 LAKALAGQKDEXXXXXXXXXXXXXXXXXXVTNEEVQKAATALKGSDHRRATTVSARLDAQ 1341
            L + L  Q D                     N+  +      +     R +  + R++ Q
Sbjct: 354  LRRLL-NQNDSVKYDKLKARYERFQ------NQSFKNLDYDFESVRTSRQSPFAQRIEQQ 406

Query: 1342 QKKLNLPVLPTTTIGSFPQTVELRRVRREYKAKKISEEEYTNAIKEEISKVVKIQEELDI 1521
            QK+LNLP LPTTTIGSFPQ+ E+R+ R ++K K+I++E Y   +K EI++ +KIQE++ +
Sbjct: 407  QKRLNLPDLPTTTIGSFPQSREVRKYRADWKNKRITDEAYETFLKNEIARWIKIQEDIGL 466

Query: 1522 DVLVHGEPERNDMVEYFGEQLSGFTFTANGWVQSYGSRCVKPPIIYGDVSRPNPMTVFWS 1701
            DVLVHGE ERNDMVE+FGE+L GF  T  GWVQSYGSR VKPPIIYGDV    P+TV  +
Sbjct: 467  DVLVHGEFERNDMVEFFGEKLQGFLVTKFGWVQSYGSRAVKPPIIYGDVKWTAPLTVDET 526

Query: 1702 KMAQSMTARPMKGMLTGPVTILNWSFVRNDQPRFETCYQIALAIKKEVEDLEAGGIQVIQ 1881
              AQS+T +P+KGMLTGPVTILNWSF R D PR     QIALAI +EV  LEA GI+VIQ
Sbjct: 527  VYAQSLTDKPVKGMLTGPVTILNWSFERVDLPRKVVQDQIALAINEEVLALEAAGIKVIQ 586

Query: 1882 IDEAALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDTTQIHTHMCYSNFNDIIQSIINM 2061
            +DE ALREGLPLR   H  YL  AV SF++    V+D TQIHTHMCYS F  II +I ++
Sbjct: 587  VDEPALREGLPLRSEYHEQYLKDAVLSFKLATSSVRDETQIHTHMCYSQFGQIIHAIHDL 646

Query: 2062 DADVITIENSRSDEKLLSVFREGVVYGAGIGPGVYDIHSPRIPSKEEIADRVNKMLAVLD 2241
            DADVI+IE SRS   L+  F E + Y  GIG GVYDIHSPRIP+KEEI   +N+ L  +D
Sbjct: 647  DADVISIETSRSHGDLIKDF-EDINYDLGIGLGVYDIHSPRIPTKEEITTAINRSLQQID 705

Query: 2242 TNILWVNPDCGLKTRKYAEVKPALTNMVEAAKQIRAE 2352
             ++ WVNPDCGLKTRK  EVK ALT +V A K  R E
Sbjct: 706  RSLFWVNPDCGLKTRKEEEVKDALTVLVNAVKAKRQE 742

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>P65342:METE_STAAM 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase|
            - Staphylococcus aureus (strain Mu50 / ATCC 700699)
          Length = 742

 Score =  576 bits (1484), Expect = e-163
 Identities = 339/757 (44%), Positives = 454/757 (59%), Gaps = 2/757 (0%)
 Frame = +1

Query: 88   VGYPRMGPKRELKFALESFWDGKSSAEDLEKVATDLRASIWKQMAGAGIKYIPSNTFAYY 267
            +G+PR+G KRE K A+ES+W  K S E+L++  TDL            +  IP   F+ Y
Sbjct: 9    LGFPRLGRKREWKKAIESYWAKKISKEELDQTLTDLHKENLLLQKYYHLDSIPVGDFSLY 68

Query: 268  DQVLDTTAMLGAVPDRYSWTGGEINLSTYFSMARGNATVPAMEMTKWFDTNYHFIVPELG 447
            D +LDT+ +   +P+R+   G  I+    F +ARGN    A  + KWF+TNYH+IVPE  
Sbjct: 69   DHILDTSLLFNIIPERFQ--GRTIDDDLLFDIARGNKDHVASALIKWFNTNYHYIVPEWD 126

Query: 448  PDTKFSYSSHKAINEYKEAKALGVDTVPVLVGPVSYLLLSKAAKGVEKSFXXXXXXXXXX 627
             + +   S +  ++ +K A++L V+  PV+VGP++++ LSK   G  ++F          
Sbjct: 127  -NVEPKVSRNVLLDRFKYAQSLNVNAHPVIVGPITFVKLSK---GGHQTFEEKVKTLLP- 181

Query: 628  XVYKEVIAELKAAGASWIQFDEPTLVKDPESHQLAAFSAAYTELESTLSGLNVLVETYFA 807
             +YKEV   L  AGA +IQ DEP LV D           AY   E       ++++TYF 
Sbjct: 182  -LYKEVFESLIDAGAEYIQVDEPILVTDDSESYENITREAYDYFEKAGVAKKLVIQTYFE 240

Query: 808  DVPAESYKTLTSLSSVTAYGFDL--ERGTKTLELVKSGFPAGKYLFAGVVDGRYIWADDL 981
                   K L+SL  V   G D   + G    ++    F   K L+AG++DGR +WA D+
Sbjct: 241  RA---HLKFLSSLP-VGGLGLDFVHDNGYNLKQIEAGDFDKSKTLYAGIIDGRNVWASDI 296

Query: 982  AASLATLQSLEAIVGKDKLVVSTSCSLMHTAVDLVNETKLDDEIKSWLAFAAQKVVEVNA 1161
             A    +  L  +   ++LV+  S SL+H  V L +ET LD  +   L+FA +K+ E++A
Sbjct: 297  EAKKVLIDKL--LAHTNELVIQPSSSLLHVPVSLDDET-LDTSVGEGLSFATEKLDELDA 353

Query: 1162 LAKALAGQKDEXXXXXXXXXXXXXXXXXXVTNEEVQKAATALKGSDHRRATTVSARLDAQ 1341
            L + L  Q D                     N+  +      +     R +  + R++ Q
Sbjct: 354  LRRLL-NQNDSVKYDKLKARYERFQ------NQSFKNLDYDFESVRTSRQSPFAQRIEQQ 406

Query: 1342 QKKLNLPVLPTTTIGSFPQTVELRRVRREYKAKKISEEEYTNAIKEEISKVVKIQEELDI 1521
            QK+LNLP LPTTTIGSFPQ+ E+R+ R ++K K+I++E Y   +K EI++ +KIQE++ +
Sbjct: 407  QKRLNLPDLPTTTIGSFPQSREVRKYRADWKNKRITDEAYETFLKNEIARWIKIQEDIGL 466

Query: 1522 DVLVHGEPERNDMVEYFGEQLSGFTFTANGWVQSYGSRCVKPPIIYGDVSRPNPMTVFWS 1701
            DVLVHGE ERNDMVE+FGE+L GF  T  GWVQSYGSR VKPPIIYGDV    P+TV  +
Sbjct: 467  DVLVHGEFERNDMVEFFGEKLQGFLVTKFGWVQSYGSRAVKPPIIYGDVKWTAPLTVDET 526

Query: 1702 KMAQSMTARPMKGMLTGPVTILNWSFVRNDQPRFETCYQIALAIKKEVEDLEAGGIQVIQ 1881
              AQS+T +P+KGMLTGPVTILNWSF R D PR     QIALAI +EV  LEA GI+VIQ
Sbjct: 527  VYAQSLTDKPVKGMLTGPVTILNWSFERVDLPRKVVQDQIALAINEEVLALEAAGIKVIQ 586

Query: 1882 IDEAALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDTTQIHTHMCYSNFNDIIQSIINM 2061
            +DE ALREGLPLR   H  YL  AV SF++    V+D TQIHTHMCYS F  II +I ++
Sbjct: 587  VDEPALREGLPLRSEYHEQYLKDAVLSFKLATSSVRDETQIHTHMCYSQFGQIIHAIHDL 646

Query: 2062 DADVITIENSRSDEKLLSVFREGVVYGAGIGPGVYDIHSPRIPSKEEIADRVNKMLAVLD 2241
            DADVI+IE SRS   L+  F E + Y  GIG GVYDIHSPRIP+KEEI   +N+ L  +D
Sbjct: 647  DADVISIETSRSHGDLIKDF-EDINYDLGIGLGVYDIHSPRIPTKEEITTAINRSLQQID 705

Query: 2242 TNILWVNPDCGLKTRKYAEVKPALTNMVEAAKQIRAE 2352
             ++ WVNPDCGLKTRK  EVK ALT +V A K  R E
Sbjct: 706  RSLFWVNPDCGLKTRKEEEVKDALTVLVNAVKAKRQE 742

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>Q8NY94:METE_STAAW 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase|
            - Staphylococcus aureus (strain MW2)
          Length = 742

 Score =  575 bits (1483), Expect = e-163
 Identities = 339/757 (44%), Positives = 454/757 (59%), Gaps = 2/757 (0%)
 Frame = +1

Query: 88   VGYPRMGPKRELKFALESFWDGKSSAEDLEKVATDLRASIWKQMAGAGIKYIPSNTFAYY 267
            +G+PR+G KRE K A+ES+W  K S E+L++  TDL            +  IP   F+ Y
Sbjct: 9    LGFPRLGRKREWKKAIESYWAKKISKEELDQTLTDLHKENLLLQKYYHLDSIPVGDFSLY 68

Query: 268  DQVLDTTAMLGAVPDRYSWTGGEINLSTYFSMARGNATVPAMEMTKWFDTNYHFIVPELG 447
            D +LDT+ +   +P+R+   G  I+    F +ARGN    A  + KWF+TNYH+IVPE  
Sbjct: 69   DHILDTSLLFNIIPERFQ--GRTIDDDLLFDIARGNKDHVASALIKWFNTNYHYIVPEWD 126

Query: 448  PDTKFSYSSHKAINEYKEAKALGVDTVPVLVGPVSYLLLSKAAKGVEKSFXXXXXXXXXX 627
             + +   S +  ++ +K A++L V+  PV+VGP++++ LSK   G  ++F          
Sbjct: 127  -NVEPKVSRNVLLDRFKYAQSLNVNAHPVIVGPITFVKLSK---GGHQTFEEKVKTLLP- 181

Query: 628  XVYKEVIAELKAAGASWIQFDEPTLVKDPESHQLAAFSAAYTELESTLSGLNVLVETYFA 807
             +YKEV   L  AGA +IQ DEP LV D           AY   E       ++++TYF 
Sbjct: 182  -LYKEVFESLIDAGAEYIQVDEPILVTDDSESYENITREAYDYFEKAGVAKKLVIQTYFE 240

Query: 808  DVPAESYKTLTSLSSVTAYGFDL--ERGTKTLELVKSGFPAGKYLFAGVVDGRYIWADDL 981
                   K L+SL  V   G D   + G    ++    F   K L+AG++DGR +WA D+
Sbjct: 241  RA---HLKFLSSLP-VGGLGLDFVHDNGYNLKQIEAGDFDKSKTLYAGIIDGRNVWASDI 296

Query: 982  AASLATLQSLEAIVGKDKLVVSTSCSLMHTAVDLVNETKLDDEIKSWLAFAAQKVVEVNA 1161
             A    +  L  +   ++LV+  S SL+H  V L +ET LD  +   L+FA +K+ E++A
Sbjct: 297  EAKKVLIDKL--LAHTNELVIQPSSSLLHVPVSLDDET-LDTSVGEGLSFATEKLDELDA 353

Query: 1162 LAKALAGQKDEXXXXXXXXXXXXXXXXXXVTNEEVQKAATALKGSDHRRATTVSARLDAQ 1341
            L + L  Q D                     N+  +      +     R +  + R++ Q
Sbjct: 354  LRR-LFNQNDSVKYDKLKARYERFQ------NQSFKNLDYDFESVRTSRQSPFAQRIEQQ 406

Query: 1342 QKKLNLPVLPTTTIGSFPQTVELRRVRREYKAKKISEEEYTNAIKEEISKVVKIQEELDI 1521
            QK+LNLP LPTTTIGSFPQ+ E+R+ R ++K K+I++E Y   +K EI++ +KIQE++ +
Sbjct: 407  QKRLNLPDLPTTTIGSFPQSREVRKYRADWKNKRITDEAYETFLKNEIARWIKIQEDIGL 466

Query: 1522 DVLVHGEPERNDMVEYFGEQLSGFTFTANGWVQSYGSRCVKPPIIYGDVSRPNPMTVFWS 1701
            DVLVHGE ERNDMVE+FGE+L GF  T  GWVQSYGSR VKPPIIYGDV    P+TV  +
Sbjct: 467  DVLVHGEFERNDMVEFFGEKLQGFLVTKFGWVQSYGSRAVKPPIIYGDVKWTAPLTVDET 526

Query: 1702 KMAQSMTARPMKGMLTGPVTILNWSFVRNDQPRFETCYQIALAIKKEVEDLEAGGIQVIQ 1881
              AQS+T +P+KGMLTGPVTILNWSF R D PR     QIALAI +EV  LEA GI+VIQ
Sbjct: 527  VYAQSLTDKPVKGMLTGPVTILNWSFERVDLPRKVVQDQIALAINEEVLALEAAGIKVIQ 586

Query: 1882 IDEAALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDTTQIHTHMCYSNFNDIIQSIINM 2061
            +DE ALREGLPLR   H  YL  AV SF++    V+D TQIHTHMCYS F  II +I ++
Sbjct: 587  VDEPALREGLPLRSEYHEQYLKDAVLSFKLATSSVRDETQIHTHMCYSQFGQIIHAIHDL 646

Query: 2062 DADVITIENSRSDEKLLSVFREGVVYGAGIGPGVYDIHSPRIPSKEEIADRVNKMLAVLD 2241
            DADVI+IE SRS   L+  F E + Y  GIG GVYDIHSPRIP+KEEI   +N+ L  +D
Sbjct: 647  DADVISIETSRSHGDLIKDF-EDINYDLGIGLGVYDIHSPRIPTKEEITTAINRSLQQID 705

Query: 2242 TNILWVNPDCGLKTRKYAEVKPALTNMVEAAKQIRAE 2352
             ++ WVNPDCGLKTRK  EVK ALT +V A K  R E
Sbjct: 706  RSLFWVNPDCGLKTRKEEEVKDALTVLVNAVKAKRQE 742

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>Q6GCB6:METE_STAAS 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase|
            - Staphylococcus aureus (strain MSSA476)
          Length = 742

 Score =  575 bits (1483), Expect = e-163
 Identities = 339/757 (44%), Positives = 454/757 (59%), Gaps = 2/757 (0%)
 Frame = +1

Query: 88   VGYPRMGPKRELKFALESFWDGKSSAEDLEKVATDLRASIWKQMAGAGIKYIPSNTFAYY 267
            +G+PR+G KRE K A+ES+W  K S E+L++  TDL            +  IP   F+ Y
Sbjct: 9    LGFPRLGRKREWKKAIESYWAKKISKEELDQTLTDLHKENLLLQKYYHLDSIPVGDFSLY 68

Query: 268  DQVLDTTAMLGAVPDRYSWTGGEINLSTYFSMARGNATVPAMEMTKWFDTNYHFIVPELG 447
            D +LDT+ +   +P+R+   G  I+    F +ARGN    A  + KWF+TNYH+IVPE  
Sbjct: 69   DHILDTSLLFNIIPERFQ--GRTIDDDLLFDIARGNKDHVASALIKWFNTNYHYIVPEWD 126

Query: 448  PDTKFSYSSHKAINEYKEAKALGVDTVPVLVGPVSYLLLSKAAKGVEKSFXXXXXXXXXX 627
             + +   S +  ++ +K A++L V+  PV+VGP++++ LSK   G  ++F          
Sbjct: 127  -NVEPKVSRNVLLDRFKYAQSLNVNAHPVIVGPITFVKLSK---GGHQTFEEKVKTLLP- 181

Query: 628  XVYKEVIAELKAAGASWIQFDEPTLVKDPESHQLAAFSAAYTELESTLSGLNVLVETYFA 807
             +YKEV   L  AGA +IQ DEP LV D           AY   E       ++++TYF 
Sbjct: 182  -LYKEVFESLIDAGAEYIQVDEPILVTDDSESYENITREAYDYFEKAGVAKKLVIQTYFE 240

Query: 808  DVPAESYKTLTSLSSVTAYGFDL--ERGTKTLELVKSGFPAGKYLFAGVVDGRYIWADDL 981
                   K L+SL  V   G D   + G    ++    F   K L+AG++DGR +WA D+
Sbjct: 241  RA---HLKFLSSLP-VGGLGLDFVHDNGYNLKQIEAGDFDKSKTLYAGIIDGRNVWASDI 296

Query: 982  AASLATLQSLEAIVGKDKLVVSTSCSLMHTAVDLVNETKLDDEIKSWLAFAAQKVVEVNA 1161
             A    +  L  +   ++LV+  S SL+H  V L +ET LD  +   L+FA +K+ E++A
Sbjct: 297  EAKKVLIDKL--LAHTNELVIQPSSSLLHVPVSLDDET-LDTSVGEGLSFATEKLDELDA 353

Query: 1162 LAKALAGQKDEXXXXXXXXXXXXXXXXXXVTNEEVQKAATALKGSDHRRATTVSARLDAQ 1341
            L + L  Q D                     N+  +      +     R +  + R++ Q
Sbjct: 354  LRR-LFNQNDSVKYDKLKARYERFQ------NQSFKNLDYDFESVRTSRQSPFAQRIEQQ 406

Query: 1342 QKKLNLPVLPTTTIGSFPQTVELRRVRREYKAKKISEEEYTNAIKEEISKVVKIQEELDI 1521
            QK+LNLP LPTTTIGSFPQ+ E+R+ R ++K K+I++E Y   +K EI++ +KIQE++ +
Sbjct: 407  QKRLNLPDLPTTTIGSFPQSREVRKYRADWKNKRITDEAYETFLKNEIARWIKIQEDIGL 466

Query: 1522 DVLVHGEPERNDMVEYFGEQLSGFTFTANGWVQSYGSRCVKPPIIYGDVSRPNPMTVFWS 1701
            DVLVHGE ERNDMVE+FGE+L GF  T  GWVQSYGSR VKPPIIYGDV    P+TV  +
Sbjct: 467  DVLVHGEFERNDMVEFFGEKLQGFLVTKFGWVQSYGSRAVKPPIIYGDVKWTAPLTVDET 526

Query: 1702 KMAQSMTARPMKGMLTGPVTILNWSFVRNDQPRFETCYQIALAIKKEVEDLEAGGIQVIQ 1881
              AQS+T +P+KGMLTGPVTILNWSF R D PR     QIALAI +EV  LEA GI+VIQ
Sbjct: 527  VYAQSLTDKPVKGMLTGPVTILNWSFERVDLPRKVVQDQIALAINEEVLALEAAGIKVIQ 586

Query: 1882 IDEAALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDTTQIHTHMCYSNFNDIIQSIINM 2061
            +DE ALREGLPLR   H  YL  AV SF++    V+D TQIHTHMCYS F  II +I ++
Sbjct: 587  VDEPALREGLPLRSEYHEQYLKDAVLSFKLATSSVRDETQIHTHMCYSQFGQIIHAIHDL 646

Query: 2062 DADVITIENSRSDEKLLSVFREGVVYGAGIGPGVYDIHSPRIPSKEEIADRVNKMLAVLD 2241
            DADVI+IE SRS   L+  F E + Y  GIG GVYDIHSPRIP+KEEI   +N+ L  +D
Sbjct: 647  DADVISIETSRSHGDLIKDF-EDINYDLGIGLGVYDIHSPRIPTKEEITTAINRSLQQID 705

Query: 2242 TNILWVNPDCGLKTRKYAEVKPALTNMVEAAKQIRAE 2352
             ++ WVNPDCGLKTRK  EVK ALT +V A K  R E
Sbjct: 706  RSLFWVNPDCGLKTRKEEEVKDALTVLVNAVKAKRQE 742

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>Q6GJW2:METE_STAAR 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase|
            - Staphylococcus aureus (strain MRSA252)
          Length = 742

 Score =  575 bits (1483), Expect = e-163
 Identities = 339/757 (44%), Positives = 454/757 (59%), Gaps = 2/757 (0%)
 Frame = +1

Query: 88   VGYPRMGPKRELKFALESFWDGKSSAEDLEKVATDLRASIWKQMAGAGIKYIPSNTFAYY 267
            +G+PR+G KRE K A+ES+W  K S E+L++  TDL            +  IP   F+ Y
Sbjct: 9    LGFPRLGRKREWKKAIESYWAKKISKEELDQTLTDLHKENLLLQKYYHLDSIPVGDFSLY 68

Query: 268  DQVLDTTAMLGAVPDRYSWTGGEINLSTYFSMARGNATVPAMEMTKWFDTNYHFIVPELG 447
            D +LDT+ +   +P+R+   G  I+    F +ARGN    A  + KWF+TNYH+IVPE  
Sbjct: 69   DHILDTSLLFNIIPERFQ--GRTIDDDLLFDIARGNKDHVASALIKWFNTNYHYIVPEWD 126

Query: 448  PDTKFSYSSHKAINEYKEAKALGVDTVPVLVGPVSYLLLSKAAKGVEKSFXXXXXXXXXX 627
             + +   S +  ++ +K A++L V+  PV+VGP++++ LSK   G  ++F          
Sbjct: 127  -NVEPKVSRNVLLDRFKYAQSLNVNAHPVIVGPITFVKLSK---GGHQTFEEKVKTLLP- 181

Query: 628  XVYKEVIAELKAAGASWIQFDEPTLVKDPESHQLAAFSAAYTELESTLSGLNVLVETYFA 807
             +YKEV   L  AGA +IQ DEP LV D           AY   E       ++++TYF 
Sbjct: 182  -LYKEVFESLIDAGAEYIQVDEPILVTDDSESYENITREAYDYFEKAGVAKKLVIQTYFE 240

Query: 808  DVPAESYKTLTSLSSVTAYGFDL--ERGTKTLELVKSGFPAGKYLFAGVVDGRYIWADDL 981
                   K L+SL  V   G D   + G    ++    F   K L+AG++DGR +WA D+
Sbjct: 241  RA---HLKFLSSLP-VGGLGLDFVHDNGYNLKQIEAGDFDKSKTLYAGIIDGRNVWASDI 296

Query: 982  AASLATLQSLEAIVGKDKLVVSTSCSLMHTAVDLVNETKLDDEIKSWLAFAAQKVVEVNA 1161
             A    +  L  +   ++LV+  S SL+H  V L +ET LD  +   L+FA +K+ E++A
Sbjct: 297  EAKKVLIDKL--LAHTNELVIQPSSSLLHVPVSLDDET-LDTSVGEGLSFATEKLDELDA 353

Query: 1162 LAKALAGQKDEXXXXXXXXXXXXXXXXXXVTNEEVQKAATALKGSDHRRATTVSARLDAQ 1341
            L + L  Q D                     N+  +      +     R +  + R++ Q
Sbjct: 354  LRR-LFNQNDSVKYDKLKARYERFQ------NQSFKNLDYDFESVRTSRQSPFAQRIEQQ 406

Query: 1342 QKKLNLPVLPTTTIGSFPQTVELRRVRREYKAKKISEEEYTNAIKEEISKVVKIQEELDI 1521
            QK+LNLP LPTTTIGSFPQ+ E+R+ R ++K K+I++E Y   +K EI++ +KIQE++ +
Sbjct: 407  QKRLNLPDLPTTTIGSFPQSREVRKYRADWKNKRITDEAYETFLKNEIARWIKIQEDIGL 466

Query: 1522 DVLVHGEPERNDMVEYFGEQLSGFTFTANGWVQSYGSRCVKPPIIYGDVSRPNPMTVFWS 1701
            DVLVHGE ERNDMVE+FGE+L GF  T  GWVQSYGSR VKPPIIYGDV    P+TV  +
Sbjct: 467  DVLVHGEFERNDMVEFFGEKLQGFLVTKFGWVQSYGSRAVKPPIIYGDVKWTAPLTVDET 526

Query: 1702 KMAQSMTARPMKGMLTGPVTILNWSFVRNDQPRFETCYQIALAIKKEVEDLEAGGIQVIQ 1881
              AQS+T +P+KGMLTGPVTILNWSF R D PR     QIALAI +EV  LEA GI+VIQ
Sbjct: 527  VYAQSLTDKPVKGMLTGPVTILNWSFERVDLPRKVVQDQIALAINEEVLALEAAGIKVIQ 586

Query: 1882 IDEAALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDTTQIHTHMCYSNFNDIIQSIINM 2061
            +DE ALREGLPLR   H  YL  AV SF++    V+D TQIHTHMCYS F  II +I ++
Sbjct: 587  VDEPALREGLPLRSEYHEQYLKDAVLSFKLATSSVRDETQIHTHMCYSQFGQIIHAIHDL 646

Query: 2062 DADVITIENSRSDEKLLSVFREGVVYGAGIGPGVYDIHSPRIPSKEEIADRVNKMLAVLD 2241
            DADVI+IE SRS   L+  F E + Y  GIG GVYDIHSPRIP+KEEI   +N+ L  +D
Sbjct: 647  DADVISIETSRSHGDLIKDF-EDINYDLGIGLGVYDIHSPRIPTKEEITTAINRSLQQID 705

Query: 2242 TNILWVNPDCGLKTRKYAEVKPALTNMVEAAKQIRAE 2352
             ++ WVNPDCGLKTRK  EVK ALT +V A K  R E
Sbjct: 706  RSLFWVNPDCGLKTRKEEEVKDALTVLVNAVKAKRQE 742

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>Q5HIT8:METE_STAAC 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase|
            - Staphylococcus aureus (strain COL)
          Length = 742

 Score =  575 bits (1483), Expect = e-163
 Identities = 339/757 (44%), Positives = 454/757 (59%), Gaps = 2/757 (0%)
 Frame = +1

Query: 88   VGYPRMGPKRELKFALESFWDGKSSAEDLEKVATDLRASIWKQMAGAGIKYIPSNTFAYY 267
            +G+PR+G KRE K A+ES+W  K S E+L++  TDL            +  IP   F+ Y
Sbjct: 9    LGFPRLGRKREWKKAIESYWAKKISKEELDQTLTDLHKENLLLQKYYHLDSIPVGDFSLY 68

Query: 268  DQVLDTTAMLGAVPDRYSWTGGEINLSTYFSMARGNATVPAMEMTKWFDTNYHFIVPELG 447
            D +LDT+ +   +P+R+   G  I+    F +ARGN    A  + KWF+TNYH+IVPE  
Sbjct: 69   DHILDTSLLFNIIPERFQ--GRTIDDDLLFDIARGNKDHVASALIKWFNTNYHYIVPEWD 126

Query: 448  PDTKFSYSSHKAINEYKEAKALGVDTVPVLVGPVSYLLLSKAAKGVEKSFXXXXXXXXXX 627
             + +   S +  ++ +K A++L V+  PV+VGP++++ LSK   G  ++F          
Sbjct: 127  -NVEPKVSRNVLLDRFKYAQSLNVNAHPVIVGPITFVKLSK---GGHQTFEEKVKTLLP- 181

Query: 628  XVYKEVIAELKAAGASWIQFDEPTLVKDPESHQLAAFSAAYTELESTLSGLNVLVETYFA 807
             +YKEV   L  AGA +IQ DEP LV D           AY   E       ++++TYF 
Sbjct: 182  -LYKEVFESLIDAGAEYIQVDEPILVTDDSESYENITREAYDYFEKAGVAKKLVIQTYFE 240

Query: 808  DVPAESYKTLTSLSSVTAYGFDL--ERGTKTLELVKSGFPAGKYLFAGVVDGRYIWADDL 981
                   K L+SL  V   G D   + G    ++    F   K L+AG++DGR +WA D+
Sbjct: 241  RA---HLKFLSSLP-VGGIGLDFVHDNGYNLKQIEAGDFDKSKTLYAGIIDGRNVWASDI 296

Query: 982  AASLATLQSLEAIVGKDKLVVSTSCSLMHTAVDLVNETKLDDEIKSWLAFAAQKVVEVNA 1161
             A    +  L  +   ++LV+  S SL+H  V L +ET LD  +   L+FA +K+ E++A
Sbjct: 297  EAKKVLIDKL--LAHTNELVIQPSSSLLHVPVSLDDET-LDTSVGEGLSFATEKLDELDA 353

Query: 1162 LAKALAGQKDEXXXXXXXXXXXXXXXXXXVTNEEVQKAATALKGSDHRRATTVSARLDAQ 1341
            L + L  Q D                     N+  +      +     R +  + R++ Q
Sbjct: 354  LRR-LFNQNDSVKYDKLKARYERFQ------NQSFKNLDYDFESVRTSRQSPFAQRIEQQ 406

Query: 1342 QKKLNLPVLPTTTIGSFPQTVELRRVRREYKAKKISEEEYTNAIKEEISKVVKIQEELDI 1521
            QK+LNLP LPTTTIGSFPQ+ E+R+ R ++K K+I++E Y   +K EI++ +KIQE++ +
Sbjct: 407  QKRLNLPDLPTTTIGSFPQSREVRKYRADWKNKRITDEAYETFLKNEIARWIKIQEDIGL 466

Query: 1522 DVLVHGEPERNDMVEYFGEQLSGFTFTANGWVQSYGSRCVKPPIIYGDVSRPNPMTVFWS 1701
            DVLVHGE ERNDMVE+FGE+L GF  T  GWVQSYGSR VKPPIIYGDV    P+TV  +
Sbjct: 467  DVLVHGEFERNDMVEFFGEKLQGFLVTKFGWVQSYGSRAVKPPIIYGDVKWTAPLTVDET 526

Query: 1702 KMAQSMTARPMKGMLTGPVTILNWSFVRNDQPRFETCYQIALAIKKEVEDLEAGGIQVIQ 1881
              AQS+T +P+KGMLTGPVTILNWSF R D PR     QIALAI +EV  LEA GI+VIQ
Sbjct: 527  VYAQSLTDKPVKGMLTGPVTILNWSFERVDLPRKVVQDQIALAINEEVLALEAAGIKVIQ 586

Query: 1882 IDEAALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDTTQIHTHMCYSNFNDIIQSIINM 2061
            +DE ALREGLPLR   H  YL  AV SF++    V+D TQIHTHMCYS F  II +I ++
Sbjct: 587  VDEPALREGLPLRSEYHEQYLKDAVLSFKLATSSVRDETQIHTHMCYSQFGQIIHAIHDL 646

Query: 2062 DADVITIENSRSDEKLLSVFREGVVYGAGIGPGVYDIHSPRIPSKEEIADRVNKMLAVLD 2241
            DADVI+IE SRS   L+  F E + Y  GIG GVYDIHSPRIP+KEEI   +N+ L  +D
Sbjct: 647  DADVISIETSRSHGDLIKDF-EDINYDLGIGLGVYDIHSPRIPTKEEITTAINRSLQQID 705

Query: 2242 TNILWVNPDCGLKTRKYAEVKPALTNMVEAAKQIRAE 2352
             ++ WVNPDCGLKTRK  EVK ALT +V A K  R E
Sbjct: 706  RSLFWVNPDCGLKTRKEEEVKDALTVLVNAVKAKRQE 742

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>P65345:METE_STRA5 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase|
            - Streptococcus agalactiae serotype V
          Length = 745

 Score =  573 bits (1476), Expect = e-162
 Identities = 340/772 (44%), Positives = 452/772 (58%), Gaps = 16/772 (2%)
 Frame = +1

Query: 88   VGYPRMGPKRELKFALESFWDGKSSAEDLEKVATDLRASIWKQMAGAGIKYIPSNTFAYY 267
            +GYPR+G +RE K A+E+FW G    +DLEK    LR +  K+   AGI  IP   F+ Y
Sbjct: 7    LGYPRLGEQREWKQAIEAFWAGNLEQKDLEKQLKQLRINHLKKQKEAGIDLIPVGDFSCY 66

Query: 268  DQVLDTTAMLGAVPDRYSWTGGEINLSTYFSMARGNATVPAMEMTKWFDTNYHFIVPELG 447
            D VLD +     +P R+     E NL  YF++ARG+    A  M KWF+TNYH+IVPE  
Sbjct: 67   DHVLDLSFQFNVIPKRFDEY--ERNLDLYFAIARGDKDNVASSMKKWFNTNYHYIVPEWE 124

Query: 448  PDTKFSYSSHKAINEYKEAK-ALGVDTVPVLVGPVSYLLLSKAAKGVEKSFXXXXXXXXX 624
             +TK    ++  ++ Y EA+  +G    PV+ GP++Y+ LS      E +          
Sbjct: 125  VETKPHLQNNYLLDLYLEAREVVGDKAKPVITGPITYVSLSSGIVDFEATVQRLLP---- 180

Query: 625  XXVYKEVIAELKAAGASWIQFDEPTLVKDPESHQLAAFSAAYTELESTLSGLNVLVETYF 804
              +YK+V  +L  AGA++IQ DEP  V D     +    + Y      +   + + +TYF
Sbjct: 181  --LYKQVFQDLIDAGATYIQIDEPIFVTDEGELLVDIAKSVYDFFAREVPQAHFIFQTYF 238

Query: 805  ADVPAESYKTLTSLSS--VTAYGFDLERG-TKTLELVKSGFPAGKYLFAGVVDGRYIWAD 975
                 ES   L  LS   VT +G D   G  + L  VK G    K LFAG+V+GR IWA 
Sbjct: 239  -----ESAVCLDKLSKLPVTGFGLDFIHGRAENLAAVKQGLFREKELFAGIVNGRNIWAV 293

Query: 976  DLAASLATLQSLEAIVGKDKLVVSTSCSLMHTAVDLVNETKLDDEIKSWLAFAAQKVVEV 1155
            +L  +LA L+ +   V   +L +  S SL+H  V    ET LD  +K+ L+FA +K+ E+
Sbjct: 294  NLEETLALLEEIGPFV--KRLTLQPSSSLLHVPVTTKYETHLDPVLKNGLSFADEKLKEL 351

Query: 1156 NALAKALAGQKDEXXXXXXXXXXXXXXXXXXVTNEEVQKAATALKGSDHRRATTVSA--- 1326
              LA A  G K +                      E     +AL+ +D R     S    
Sbjct: 352  ELLASAFDGNKTKGY-------------------HEALSRFSALQAADFRHVALESLAEV 392

Query: 1327 ---------RLDAQQKKLNLPVLPTTTIGSFPQTVELRRVRREYKAKKISEEEYTNAIKE 1479
                     R   Q +KL LP+LPTTTIGSFPQ+ E+R+ R  +K   +S+ +Y + IK 
Sbjct: 393  KLERSPYKLRQALQAEKLQLPILPTTTIGSFPQSPEIRKKRLAWKRGNLSDSDYKDFIKT 452

Query: 1480 EISKVVKIQEELDIDVLVHGEPERNDMVEYFGEQLSGFTFTANGWVQSYGSRCVKPPIIY 1659
            EI + + IQE+LD+DVLVHGE ER DMVE+FG++L+GFT T  GWVQSYGSR VKPPIIY
Sbjct: 453  EIRRWIAIQEDLDLDVLVHGEFERVDMVEFFGQKLAGFTTTKLGWVQSYGSRAVKPPIIY 512

Query: 1660 GDVSRPNPMTVFWSKMAQSMTARPMKGMLTGPVTILNWSFVRNDQPRFETCYQIALAIKK 1839
            GDV    P+++  +  AQS+T +P+KGMLTGP+TI NWSF R+D  R +   QIALAIK 
Sbjct: 513  GDVKHIQPLSLEETVYAQSLTKKPVKGMLTGPITITNWSFERDDISRSDLFNQIALAIKD 572

Query: 1840 EVEDLEAGGIQVIQIDEAALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDTTQIHTHMC 2019
            E++ LE  GI +IQ+DEAALREGLPLR+ +   YLD AV +F+I    V+D TQIHTHMC
Sbjct: 573  EIQLLEQSGIAIIQVDEAALREGLPLRQQKQQAYLDDAVAAFKIATSSVKDETQIHTHMC 632

Query: 2020 YSNFNDIIQSIINMDADVITIENSRSDEKLLSVFREGVVYGAGIGPGVYDIHSPRIPSKE 2199
            YS F++II SI  +DADVI+IE SRS   ++  F E  VY  GIG GVYDIHSPRIP+KE
Sbjct: 633  YSKFDEIIDSIRALDADVISIETSRSHGDIIESF-ETAVYPLGIGLGVYDIHSPRIPTKE 691

Query: 2200 EIADRVNKMLAVLDTNILWVNPDCGLKTRKYAEVKPALTNMVEAAKQIRAEL 2355
            EI   + + L  L     WVNPDCGLKTR+ AE   AL  +V A K++R +L
Sbjct: 692  EIIVNIQRSLKCLSKEQFWVNPDCGLKTRREAETIAALEVLVSATKEVRQQL 743

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>P65344:METE_STRA3 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase|
            - Streptococcus agalactiae serotype III
          Length = 745

 Score =  573 bits (1476), Expect = e-162
 Identities = 340/772 (44%), Positives = 452/772 (58%), Gaps = 16/772 (2%)
 Frame = +1

Query: 88   VGYPRMGPKRELKFALESFWDGKSSAEDLEKVATDLRASIWKQMAGAGIKYIPSNTFAYY 267
            +GYPR+G +RE K A+E+FW G    +DLEK    LR +  K+   AGI  IP   F+ Y
Sbjct: 7    LGYPRLGEQREWKQAIEAFWAGNLEQKDLEKQLKQLRINHLKKQKEAGIDLIPVGDFSCY 66

Query: 268  DQVLDTTAMLGAVPDRYSWTGGEINLSTYFSMARGNATVPAMEMTKWFDTNYHFIVPELG 447
            D VLD +     +P R+     E NL  YF++ARG+    A  M KWF+TNYH+IVPE  
Sbjct: 67   DHVLDLSFQFNVIPKRFDEY--ERNLDLYFAIARGDKDNVASSMKKWFNTNYHYIVPEWE 124

Query: 448  PDTKFSYSSHKAINEYKEAK-ALGVDTVPVLVGPVSYLLLSKAAKGVEKSFXXXXXXXXX 624
             +TK    ++  ++ Y EA+  +G    PV+ GP++Y+ LS      E +          
Sbjct: 125  VETKPHLQNNYLLDLYLEAREVVGDKAKPVITGPITYVSLSSGIVDFEATVQRLLP---- 180

Query: 625  XXVYKEVIAELKAAGASWIQFDEPTLVKDPESHQLAAFSAAYTELESTLSGLNVLVETYF 804
              +YK+V  +L  AGA++IQ DEP  V D     +    + Y      +   + + +TYF
Sbjct: 181  --LYKQVFQDLIDAGATYIQIDEPIFVTDEGELLVDIAKSVYDFFAREVPQAHFIFQTYF 238

Query: 805  ADVPAESYKTLTSLSS--VTAYGFDLERG-TKTLELVKSGFPAGKYLFAGVVDGRYIWAD 975
                 ES   L  LS   VT +G D   G  + L  VK G    K LFAG+V+GR IWA 
Sbjct: 239  -----ESAVCLDKLSKLPVTGFGLDFIHGRAENLAAVKQGLFREKELFAGIVNGRNIWAV 293

Query: 976  DLAASLATLQSLEAIVGKDKLVVSTSCSLMHTAVDLVNETKLDDEIKSWLAFAAQKVVEV 1155
            +L  +LA L+ +   V   +L +  S SL+H  V    ET LD  +K+ L+FA +K+ E+
Sbjct: 294  NLEETLALLEEIGPFV--KRLTLQPSSSLLHVPVTTKYETHLDPVLKNGLSFADEKLKEL 351

Query: 1156 NALAKALAGQKDEXXXXXXXXXXXXXXXXXXVTNEEVQKAATALKGSDHRRATTVSA--- 1326
              LA A  G K +                      E     +AL+ +D R     S    
Sbjct: 352  ELLASAFDGNKTKGY-------------------HEALSRFSALQAADFRHVALESLAEV 392

Query: 1327 ---------RLDAQQKKLNLPVLPTTTIGSFPQTVELRRVRREYKAKKISEEEYTNAIKE 1479
                     R   Q +KL LP+LPTTTIGSFPQ+ E+R+ R  +K   +S+ +Y + IK 
Sbjct: 393  KLERSPYKLRQALQAEKLQLPILPTTTIGSFPQSPEIRKKRLAWKRGNLSDSDYKDFIKT 452

Query: 1480 EISKVVKIQEELDIDVLVHGEPERNDMVEYFGEQLSGFTFTANGWVQSYGSRCVKPPIIY 1659
            EI + + IQE+LD+DVLVHGE ER DMVE+FG++L+GFT T  GWVQSYGSR VKPPIIY
Sbjct: 453  EIRRWIAIQEDLDLDVLVHGEFERVDMVEFFGQKLAGFTTTKLGWVQSYGSRAVKPPIIY 512

Query: 1660 GDVSRPNPMTVFWSKMAQSMTARPMKGMLTGPVTILNWSFVRNDQPRFETCYQIALAIKK 1839
            GDV    P+++  +  AQS+T +P+KGMLTGP+TI NWSF R+D  R +   QIALAIK 
Sbjct: 513  GDVKHIQPLSLEETVYAQSLTKKPVKGMLTGPITITNWSFERDDISRSDLFNQIALAIKD 572

Query: 1840 EVEDLEAGGIQVIQIDEAALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDTTQIHTHMC 2019
            E++ LE  GI +IQ+DEAALREGLPLR+ +   YLD AV +F+I    V+D TQIHTHMC
Sbjct: 573  EIQLLEQSGIAIIQVDEAALREGLPLRQQKQQAYLDDAVAAFKIATSSVKDETQIHTHMC 632

Query: 2020 YSNFNDIIQSIINMDADVITIENSRSDEKLLSVFREGVVYGAGIGPGVYDIHSPRIPSKE 2199
            YS F++II SI  +DADVI+IE SRS   ++  F E  VY  GIG GVYDIHSPRIP+KE
Sbjct: 633  YSKFDEIIDSIRALDADVISIETSRSHGDIIESF-ETAVYPLGIGLGVYDIHSPRIPTKE 691

Query: 2200 EIADRVNKMLAVLDTNILWVNPDCGLKTRKYAEVKPALTNMVEAAKQIRAEL 2355
            EI   + + L  L     WVNPDCGLKTR+ AE   AL  +V A K++R +L
Sbjct: 692  EIIVNIQRSLKCLSKEQFWVNPDCGLKTRREAETIAALEVLVSATKEVRQQL 743

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>Q5HS05:METE_STAEQ 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase|
            - Staphylococcus epidermidis (strain ATCC 35984 / RP62A)
          Length = 748

 Score =  570 bits (1470), Expect = e-162
 Identities = 332/757 (43%), Positives = 453/757 (59%), Gaps = 2/757 (0%)
 Frame = +1

Query: 88   VGYPRMGPKRELKFALESFWDGKSSAEDLEKVATDLRASIWKQMAGAGIKYIPSNTFAYY 267
            +G+PR+G KRE K A+E++W  K    +L++  TDL            +  IP   F+ Y
Sbjct: 9    LGFPRLGRKREWKKAIENYWAHKIDKAELDQTLTDLHKENLLLQKNYHLDSIPVGDFSLY 68

Query: 268  DQVLDTTAMLGAVPDRYSWTGGEINLSTYFSMARGNATVPAMEMTKWFDTNYHFIVPELG 447
            D +LDT+ +   +P+R+   G E+N    F +ARGN    A  + KWF+TNYH+IVPE  
Sbjct: 69   DHILDTSLLFNIIPERFQ--GREVNDDLLFDIARGNKEHVASALIKWFNTNYHYIVPE-W 125

Query: 448  PDTKFSYSSHKAINEYKEAKALGVDTVPVLVGPVSYLLLSKAAKGVEKSFXXXXXXXXXX 627
             + +     +  +  +K A+++ V+  PV+VGP++++ LS   KG  +SF          
Sbjct: 126  DNVEPKVEKNTLLERFKYAQSINVNAHPVIVGPITFVKLS---KGGHQSF--EEKVETLL 180

Query: 628  XVYKEVIAELKAAGASWIQFDEPTLVKDPESHQLAAFSAAYTELESTLSGLNVLVETYFA 807
             +YKEV+  L  AGA +IQ DEP LV D           AY    +   G  ++++TYF 
Sbjct: 181  PLYKEVLQSLVDAGAEYIQIDEPILVTDDSESYEDITRKAYDYFANEGLGKYLVIQTYFE 240

Query: 808  DVPAESYKTLTSLSSVTAYGFDL--ERGTKTLELVKSGFPAGKYLFAGVVDGRYIWADDL 981
             V     K L+SL  V   G DL  + G    ++    F   K L+AG++DGR +WA D+
Sbjct: 241  RV---HLKFLSSL-PVGGLGLDLVHDNGYNLKQIEDGDFDQSKALYAGIIDGRNVWAADI 296

Query: 982  AASLATLQSLEAIVGKDKLVVSTSCSLMHTAVDLVNETKLDDEIKSWLAFAAQKVVEVNA 1161
             A    +++L+      +LV+  S SL+H  V L +ET LD+ I   L+FA +K+ E++A
Sbjct: 297  EAKKQLIETLQQ--HTQQLVIQPSSSLLHVPVSLDDET-LDESIAEGLSFATEKLDELDA 353

Query: 1162 LAKALAGQKDEXXXXXXXXXXXXXXXXXXVTNEEVQKAATALKGSDHRRATTVSARLDAQ 1341
            L + L    D                     ++  +      +     R +  + R   Q
Sbjct: 354  L-RRLFNDND------LSKYEHYKARYERFQSQSFKNLEYDFESVPTHRKSPFAKRKQLQ 406

Query: 1342 QKKLNLPVLPTTTIGSFPQTVELRRVRREYKAKKISEEEYTNAIKEEISKVVKIQEELDI 1521
             ++LNLP LPTTTIGSFPQT E+R+ R ++K  +I++ EY   ++ EI++ +KIQE++ +
Sbjct: 407  NQRLNLPDLPTTTIGSFPQTREIRKFRADWKNNRITDAEYQEFLQNEIARWIKIQEDIGL 466

Query: 1522 DVLVHGEPERNDMVEYFGEQLSGFTFTANGWVQSYGSRCVKPPIIYGDVSRPNPMTVFWS 1701
            DVLVHGE ERNDMVE+FGE+L GF  T  GWVQSYGSR VKPP+IYGDV    P+TV  +
Sbjct: 467  DVLVHGEFERNDMVEFFGEKLQGFLVTKFGWVQSYGSRAVKPPVIYGDVKWTAPLTVKET 526

Query: 1702 KMAQSMTARPMKGMLTGPVTILNWSFVRNDQPRFETCYQIALAIKKEVEDLEAGGIQVIQ 1881
              AQS+T +P+KGMLTGPVTILNWSF R D PR     QIALAI +EV  LE  GI+VIQ
Sbjct: 527  VYAQSLTDKPVKGMLTGPVTILNWSFERVDVPRKVVQDQIALAIDEEVLALEEAGIKVIQ 586

Query: 1882 IDEAALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDTTQIHTHMCYSNFNDIIQSIINM 2061
            +DE ALREGLPLR   H  YL+ AVHSF++    V D TQIHTHMCYS F  II +I ++
Sbjct: 587  VDEPALREGLPLRSEYHEQYLEDAVHSFKLATSSVHDETQIHTHMCYSQFGQIIHAIHDL 646

Query: 2062 DADVITIENSRSDEKLLSVFREGVVYGAGIGPGVYDIHSPRIPSKEEIADRVNKMLAVLD 2241
            DADVI+IE SRS   L+  F E + Y  GIG GVYDIHSPRIP++EEI   +N+ L  +D
Sbjct: 647  DADVISIETSRSHGDLIQDF-EDINYDLGIGLGVYDIHSPRIPTEEEITTAINRSLQQID 705

Query: 2242 TNILWVNPDCGLKTRKYAEVKPALTNMVEAAKQIRAE 2352
             ++ WVNPDCGLKTRK  EVK ALT +V A K+ R E
Sbjct: 706  RSLFWVNPDCGLKTRKENEVKDALTVLVNAVKKKRQE 742

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>Q8CMP5:METE_STAES 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase|
            - Staphylococcus epidermidis (strain ATCC 12228)
          Length = 748

 Score =  570 bits (1469), Expect = e-161
 Identities = 332/757 (43%), Positives = 453/757 (59%), Gaps = 2/757 (0%)
 Frame = +1

Query: 88   VGYPRMGPKRELKFALESFWDGKSSAEDLEKVATDLRASIWKQMAGAGIKYIPSNTFAYY 267
            +G+PR+G KRE K A+E++W  K    +L++  TDL            +  IP   F+ Y
Sbjct: 9    LGFPRLGRKREWKKAIENYWAHKIDKAELDQTLTDLHKENLLLQKNYHLDSIPVGDFSLY 68

Query: 268  DQVLDTTAMLGAVPDRYSWTGGEINLSTYFSMARGNATVPAMEMTKWFDTNYHFIVPELG 447
            D +LDT+ +   +P+R+   G E+N    F +ARGN    A  + KWF+TNYH+IVPE  
Sbjct: 69   DHILDTSLLFNIIPERFQ--GREVNDDLLFDIARGNKEHVASALIKWFNTNYHYIVPE-W 125

Query: 448  PDTKFSYSSHKAINEYKEAKALGVDTVPVLVGPVSYLLLSKAAKGVEKSFXXXXXXXXXX 627
             + +     +  +  +K A+++ V+  PV+VGP++++ LS   KG  +SF          
Sbjct: 126  DNVEPKVEKNTLLERFKYAQSINVNAHPVIVGPITFVKLS---KGGHQSF--EEKVETLL 180

Query: 628  XVYKEVIAELKAAGASWIQFDEPTLVKDPESHQLAAFSAAYTELESTLSGLNVLVETYFA 807
             +YKEV+  L  AGA +IQ DEP LV D           AY    +   G  ++++TYF 
Sbjct: 181  PLYKEVLQSLVDAGAEYIQIDEPILVTDDSESYEDITRKAYDYFANEGLGKYLVIQTYFE 240

Query: 808  DVPAESYKTLTSLSSVTAYGFDL--ERGTKTLELVKSGFPAGKYLFAGVVDGRYIWADDL 981
             V     K L+SL  V   G DL  + G    ++    F   K L+AG++DGR +WA D+
Sbjct: 241  RV---HLKFLSSL-PVGGLGLDLVHDNGYNLKQIEDGDFDQSKALYAGIIDGRNVWAADI 296

Query: 982  AASLATLQSLEAIVGKDKLVVSTSCSLMHTAVDLVNETKLDDEIKSWLAFAAQKVVEVNA 1161
             A    +++L+      +LV+  S SL+H  V L +ET LD+ I   L+FA +K+ E++A
Sbjct: 297  EAKKQLIETLQQ--HTQQLVIQPSSSLLHVPVSLDDET-LDESIAEGLSFATEKLDELDA 353

Query: 1162 LAKALAGQKDEXXXXXXXXXXXXXXXXXXVTNEEVQKAATALKGSDHRRATTVSARLDAQ 1341
            L + L    D                     ++  +      +     R +  + R   Q
Sbjct: 354  L-RRLFNDND------LSKYEHYKARYERFQSQSFKNLEYDFESVPTHRKSPFAKRKQLQ 406

Query: 1342 QKKLNLPVLPTTTIGSFPQTVELRRVRREYKAKKISEEEYTNAIKEEISKVVKIQEELDI 1521
             ++LNLP LPTTTIGSFPQT E+R+ R ++K  +I++ EY   ++ EI++ +KIQE++ +
Sbjct: 407  NQRLNLPDLPTTTIGSFPQTREVRKFRADWKNNRITDAEYQEFLQNEIARWIKIQEDIGL 466

Query: 1522 DVLVHGEPERNDMVEYFGEQLSGFTFTANGWVQSYGSRCVKPPIIYGDVSRPNPMTVFWS 1701
            DVLVHGE ERNDMVE+FGE+L GF  T  GWVQSYGSR VKPP+IYGDV    P+TV  +
Sbjct: 467  DVLVHGEFERNDMVEFFGEKLQGFLVTKFGWVQSYGSRAVKPPVIYGDVKWTAPLTVKET 526

Query: 1702 KMAQSMTARPMKGMLTGPVTILNWSFVRNDQPRFETCYQIALAIKKEVEDLEAGGIQVIQ 1881
              AQS+T +P+KGMLTGPVTILNWSF R D PR     QIALAI +EV  LE  GI+VIQ
Sbjct: 527  VYAQSLTDKPVKGMLTGPVTILNWSFERVDVPRKVVQDQIALAIDEEVLALEEAGIKVIQ 586

Query: 1882 IDEAALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDTTQIHTHMCYSNFNDIIQSIINM 2061
            +DE ALREGLPLR   H  YL+ AVHSF++    V D TQIHTHMCYS F  II +I ++
Sbjct: 587  VDEPALREGLPLRSEYHEQYLEDAVHSFKLATSSVHDETQIHTHMCYSQFGQIIHAIHDL 646

Query: 2062 DADVITIENSRSDEKLLSVFREGVVYGAGIGPGVYDIHSPRIPSKEEIADRVNKMLAVLD 2241
            DADVI+IE SRS   L+  F E + Y  GIG GVYDIHSPRIP++EEI   +N+ L  +D
Sbjct: 647  DADVISIETSRSHGDLIQDF-EDINYDLGIGLGVYDIHSPRIPTEEEITTAINRSLQQID 705

Query: 2242 TNILWVNPDCGLKTRKYAEVKPALTNMVEAAKQIRAE 2352
             ++ WVNPDCGLKTRK  EVK ALT +V A K+ R E
Sbjct: 706  RSLFWVNPDCGLKTRKENEVKDALTVLVNAVKKKRQE 742

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>Q8DJY0:METE_SYNEL 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase|
            - Synechococcus elongatus (Thermosynechococcus elongatus)
          Length = 758

 Score =  566 bits (1458), Expect = e-160
 Identities = 336/771 (43%), Positives = 451/771 (58%), Gaps = 11/771 (1%)
 Frame = +1

Query: 88   VGYPRMGPKRELKFALESFWDGKSSAEDLEKVATDLRASIWKQMAGAGIKYIPSNTFAYY 267
            +GYPR+G  RELK ALE+FW  +  AE L K A D+    W++    GI  I     + Y
Sbjct: 8    LGYPRIGKNRELKKALEAFWSNQLDAEALLKTAQDIELQNWQKQLEVGIDRIGIGDLSLY 67

Query: 268  DQVLDTTAMLGAVPDRY-SWTGGEINLSTYFSMARGNATVPAMEMTKWFDTNYHFIVPEL 444
            D VLD +   G +P+RY S+TG    L  YF+MARG   +PA+EMTKWFDTNYH++VPE+
Sbjct: 68   DSVLDWSIRFGIIPERYRSFTG----LEQYFAMARGKDGIPALEMTKWFDTNYHYLVPEI 123

Query: 445  GPDTKFSYSSHKAINEYKEAKALGVDTVPVLVGPVSYLLLSKAAKGVEKSFXXXXXXXXX 624
                + +  S       +    LG   VP+++GP++ L LS+    +E++          
Sbjct: 124  SEAFQPTDFSDFLETVRRAQTLLGDRAVPIVLGPLTLLRLSRLETNLEQAVSYLRDR--- 180

Query: 625  XXVYKEVIAELKAAGASWIQFDEPTLVKDPESHQLAAFSAAYTELESTLSGLNVLVE--T 798
               Y  ++ ELK  G   +Q  EP LV +    +  +F + Y     TL   N+ +   T
Sbjct: 181  ---YLILLRELKNLGVVEVQIHEPALVLE----EADSFKSFYQSTFDTLRQANLPLHLVT 233

Query: 799  YFADVPAESYKTLTSLSSVTAYGFDLERGTKTLELVKSGFPAGKYLFAGVVDGRYIWADD 978
            YF D+ A ++  +  L  VT    D  RG     L + GFPA K L  G++DGR IW   
Sbjct: 234  YFDDLGA-AWPWVMELP-VTCISLDFTRGHNLALLKEYGFPADKQLGVGIIDGRNIWKIR 291

Query: 979  LAASLATLQSLEAIVGKDKLVVSTSCSLMHTAVDLVNETKLDDEIKSWLAFAAQKVVEVN 1158
              + L+TL+++++I    +L    S SL     D   E KL + ++  L+FA QK+ EV 
Sbjct: 292  PESVLSTLETIQSITANIRL--HPSSSLQFVPYDAKREVKLPEPLRDVLSFAEQKLDEVV 349

Query: 1159 ALAKALAGQKD-------EXXXXXXXXXXXXXXXXXXVTNEEVQKAATALKGSDHRRATT 1317
             LA+ L            +                    N  VQ     L   D  R   
Sbjct: 350  LLARVLNSNDGTNREILMKNPELTAIQAQWKAFEQFSPVNPTVQARLRNLSVRDLERPLP 409

Query: 1318 VSARLDAQQKKLNLPVLPTTTIGSFPQTVELRRVRREYKAKKISEEEYTNAIKEEISKVV 1497
               R   Q     LP LPTTTIGSFPQT E+R++R + K  +I++ EY  AI EEI+K V
Sbjct: 410  YEQRRTLQP---TLPPLPTTTIGSFPQTAEVRQLRVKLKRHEITQAEYEAAIDEEIAKCV 466

Query: 1498 KIQEELDIDVLVHGEPERNDMVEYFGEQLSGFTFTANGWVQSYGSRCVKPPIIYGDVSRP 1677
            ++QEE+ +DVLVHGE ER+DMVE+FG+QLSGF FT +GWVQSYGSRCV+PPIIYGD++RP
Sbjct: 467  RLQEEVGLDVLVHGEFERSDMVEFFGQQLSGFAFTEHGWVQSYGSRCVRPPIIYGDIARP 526

Query: 1678 NPMTVFWSKMAQSMTARPMKGMLTGPVTILNWSFVRNDQPRFETCYQIALAIKKEVEDLE 1857
             PMTV   K+AQS+T + +K MLTGPVT++NWSF R D PR E   QIALA++ EV DLE
Sbjct: 527  QPMTVREFKVAQSLTDKIVKAMLTGPVTMINWSFTRTDIPRSEQAMQIALALRDEVADLE 586

Query: 1858 AGGIQVIQIDEAALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDTTQIHTHMCYSNFND 2037
            A G ++IQIDE ALREGLPL+      YL WAV +FR+     +  TQIHTHMCYS F D
Sbjct: 587  AAGAKMIQIDEPALREGLPLKAERWNEYLSWAVDAFRLAAGVAKPETQIHTHMCYSEFGD 646

Query: 2038 IIQSIINMDADVITIENSRS-DEKLLSVFREGVVYGAGIGPGVYDIHSPRIPSKEEIADR 2214
            II+ I  +DADV++IENSRS +E L  +   G  Y   +G GVYD+HSP +PS E++  +
Sbjct: 647  IIEHIERLDADVLSIENSRSNNETLFQITDAG--YRHQVGVGVYDVHSPAVPSVEQLVQQ 704

Query: 2215 VNKMLAVLDTNILWVNPDCGLKTRKYAEVKPALTNMVEAAKQIRAELAKAQ 2367
            +   +A L    +WVNPDCGLKTR + EV P+L NMVEA K IR E+ +++
Sbjct: 705  LRTSVANLAPEQIWVNPDCGLKTRHWEEVIPSLKNMVEATKTIRQEVMQSK 755

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>Q9X112:METE_THEMA 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase|
            - Thermotoga maritima
          Length = 734

 Score =  555 bits (1429), Expect = e-157
 Identities = 324/760 (42%), Positives = 445/760 (58%), Gaps = 2/760 (0%)
 Frame = +1

Query: 73   MASHIVGYPRMGPKRELKFALESFWDGKSSAEDLEKVATDLRASIWKQMAGAGIKYIPSN 252
            M ++  G+P++G KRE K ALE FW GK + E  E+    LR  + +      +  IPSN
Sbjct: 1    MKAYAFGFPKIGEKREFKKALEDFWKGKITEEQFEEEMNKLRMYMVENYR-KNVDVIPSN 59

Query: 253  TFAYYDQVLDTTAMLGAVPDRYSWTGGEINLSTYFSMARGNATVPAMEMTKWFDTNYHFI 432
              +YYD VLDT  M+GAVP+R+    G   LSTYF MARG     A+EMTK+F+TNYH++
Sbjct: 60   ELSYYDFVLDTAVMVGAVPERFGEYRG---LSTYFDMARGGK---ALEMTKFFNTNYHYL 113

Query: 433  VPELGPDTKFSYSSHKAINEYKEAKALGVDTVPVLVGPVSYLLLSKA-AKGVEKSFXXXX 609
            VPE+  + +F    +K + +Y   K+ G++T P ++GP ++L LSK   + + +      
Sbjct: 114  VPEIETE-EFYLLENKPLEDYLFFKSKGIETAPWVIGPFTFLYLSKRNGEWIRRPNQMEK 172

Query: 610  XXXXXXXVYKEVIAELKAAGASWIQFDEPTLVKDPESHQLAAFSAAYTELESTLSGLNVL 789
                   VYKEV  +L   G   I  +EP  V D E          Y EL    S   + 
Sbjct: 173  LLESLVSVYKEVFEKLVENGCKEILVNEPAFVCDLEKAHWDLILNVYREL----SEFPLT 228

Query: 790  VETYFADVPAESYKTLTSLSSVTAYGFDLERGTKTLE-LVKSGFPAGKYLFAGVVDGRYI 966
            V TY+  V    Y+   SL  V    FD     + L+ L K GFP  K L AGV++GR  
Sbjct: 229  VFTYYDSV--SDYEACVSLP-VKRLHFDFVSNEENLKNLEKHGFPEDKKLVAGVINGRQP 285

Query: 967  WADDLAASLATLQSLEAIVGKDKLVVSTSCSLMHTAVDLVNETKLDDEIKSWLAFAAQKV 1146
            W  DL    + ++ L A        +S SC L H  V L  E  L   +K  LAFA +K+
Sbjct: 286  WKVDLRKVASLVEKLGASA------ISNSCPLFHLPVTLELENNLPGGLKEKLAFAKEKL 339

Query: 1147 VEVNALAKALAGQKDEXXXXXXXXXXXXXXXXXXVTNEEVQKAATALKGSDHRRATTVSA 1326
             E+  L   L G+  +                  V N         L     RR    + 
Sbjct: 340  EELKMLKDFLEGKTFDLPNVSFEDFAVDLQAVERVRN---------LPEDSFRREKEYTE 390

Query: 1327 RLDAQQKKLNLPVLPTTTIGSFPQTVELRRVRREYKAKKISEEEYTNAIKEEISKVVKIQ 1506
            R   Q+++LNLP+ PTTTIGSFPQT E+R++R +Y+  +IS+EEY   IKE+I K +++Q
Sbjct: 391  RDRIQRERLNLPLFPTTTIGSFPQTPEVRKMRSKYRKGEISKEEYEAFIKEQIKKAIELQ 450

Query: 1507 EELDIDVLVHGEPERNDMVEYFGEQLSGFTFTANGWVQSYGSRCVKPPIIYGDVSRPNPM 1686
            EE+ +DVLVHGE ER DMVE+F E+L+G   T NGWV SYGSRC +PPIIYG V+RP PM
Sbjct: 451  EEIGLDVLVHGEFERTDMVEFFAEKLNGIATTQNGWVLSYGSRCYRPPIIYGTVTRPEPM 510

Query: 1687 TVFWSKMAQSMTARPMKGMLTGPVTILNWSFVRNDQPRFETCYQIALAIKKEVEDLEAGG 1866
            T+     AQS+T +P+KGMLTGPVTI++WS+ R D P  E  YQIALAI +EV+DLE  G
Sbjct: 511  TLKEITYAQSLTEKPVKGMLTGPVTIMSWSYYREDIPEREIAYQIALAINEEVKDLEEAG 570

Query: 1867 IQVIQIDEAALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDTTQIHTHMCYSNFNDIIQ 2046
            I+++QIDE A RE  P++KS+   Y +WA+++F +     +  TQIH HMCYS+FN+II+
Sbjct: 571  IKIVQIDEPAFREKAPIKKSKWPEYFEWAINAFNLA-ANARPETQIHAHMCYSDFNEIIE 629

Query: 2047 SIINMDADVITIENSRSDEKLLSVFREGVVYGAGIGPGVYDIHSPRIPSKEEIADRVNKM 2226
             I  ++ DVI+IE SRS  +++S F     +   IG GV+DIHSP +PS  E+ + V ++
Sbjct: 630  YIHQLEFDVISIEASRSKGEIISAFENFKGWIKQIGVGVWDIHSPAVPSINEMREIVERV 689

Query: 2227 LAVLDTNILWVNPDCGLKTRKYAEVKPALTNMVEAAKQIR 2346
            L VL   ++W+NPDCGLKTR + EV P+L NMV  AK++R
Sbjct: 690  LRVLPKELIWINPDCGLKTRNWDEVIPSLRNMVALAKEMR 729

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>Q39586:METE_CHLRE 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase|
            - Chlamydomonas reinhardtii
          Length = 814

 Score =  505 bits (1301), Expect = e-142
 Identities = 321/799 (40%), Positives = 441/799 (55%), Gaps = 35/799 (4%)
 Frame = +1

Query: 73   MASHIVGYPRMGPKRELKFALESFWDGKSSAEDLEKVATDLRASIWKQMAGAGIKYIPSN 252
            +++  +G+PR+G +R+LKFA+ES++ G S   +L  VA  +++  W     AGI  I  +
Sbjct: 2    LSTTTIGFPRIGNQRQLKFAMESYFKGDSGEAELLAVAHKVQSDAWALQKAAGIAVIGLD 61

Query: 253  TFAYYDQVLDTTAMLGAVPDRYSWTGGEINLSTYFSMARGNATVPAMEMTKWFDTNYHFI 432
                YDQVLDT   LGA+P R+    G   L  Y++MARG A   A++M+K+FDTNYH++
Sbjct: 62   G-TLYDQVLDTITWLGAIPPRFKHLSG---LQRYYAMARGGA---ALDMSKFFDTNYHYL 114

Query: 433  VPELGPDTKFSYSSHKAINEY------KEAKALGV----DTVPVLVGPVSYLLLSKAAKG 582
            VPELGPD     ++   +         K A+   V      VP+L+GPV+++ LS+  + 
Sbjct: 115  VPELGPDVLGPATAGPPLQPDFSGPLDKLARGQAVVGRDGAVPILIGPVTFVSLSRGCE- 173

Query: 583  VEKSFXXXXXXXXXXXVYKEVIAELKAAGASWIQFDEPTLVKDPESHQLAAFSAAYTELE 762
                             Y  ++ +L AAGA  +Q  EP L     +     F  AY ++ 
Sbjct: 174  ----LPLDQAVARLLPTYCALLQQLAAAGAPEVQLHEPVLATSEGTGMPTEFETAYAQMA 229

Query: 763  STLSGLNVLVETYFADVPAESYKTLTSLSSVTAYGFDL------ERGTKTLELVKS-GFP 921
                 + + + TY+ D+ A +Y     L  V A   D          ++TL L++  GFP
Sbjct: 230  QAAGSVPLHLVTYYDDLGA-AYPWAVQLP-VAAVTLDFLGPPGAAVPSQTLALLQQHGFP 287

Query: 922  AGKYLFAGVVDGRYIWADDLAASLATLQSL--EAIVGKDKLVVSTSCSLMHTAVDLVNET 1095
            A K L AGVVDGR +W DD   ++A L++L     V  D+LVV++S  L H   DL  E 
Sbjct: 288  ADKRLGAGVVDGRSVWKDD-GTAVALLRALLDTGAVSSDRLVVTSSAPLQHLPYDLGLEL 346

Query: 1096 KLDDEIKSWL---------AFAAQKVVEVNALAKALAGQKDEXXXXXXXXXXXXXXXXXX 1248
            +     ++            FA QKV E+ ++A+ LA                       
Sbjct: 347  EAPKTPEATAPAARAGRPPGFAKQKVEEIVSVAR-LAASPQPPLLQLVMAPWCSCSGCSR 405

Query: 1249 VTNEEVQKAATALKGSDHRRATTVSARLDAQQKKLNLPVLPTTTIGSFPQTVELRRVRRE 1428
                      + L GS    A     R  A+ ++L L   PTTTIGSFPQT E+RR+R++
Sbjct: 406  ARAWRTTPPTSRLSGS---AAKPYDVR--ARDEQLQLAAFPTTTIGSFPQTAEVRRLRQQ 460

Query: 1429 YKAKKISEEEYTNAIKEEISKVVKIQEELDIDVLVHGEPERNDMVEYFGEQLSGFTFTAN 1608
             K+ ++++ EY   I   I+  V +QE L IDVLVHGE ER DMVEYFG QL G  FT  
Sbjct: 461  LKSGRLTQAEYEGLIAGHIAHAVGVQEALGIDVLVHGEAERTDMVEYFGMQLGGMLFTRA 520

Query: 1609 GWVQSYGSRCVKPPIIYGDVSRPNPMTVFWSKMAQSMTARPMKGMLTGPVTILNWSFVRN 1788
            GWVQSYGSRCV+PP++  D++   P T +  K+A    A+P+KG+LTGPVTILNWSF R 
Sbjct: 521  GWVQSYGSRCVRPPLVVDDITYRGPSTCWEYKVAIPTAAQPVKGLLTGPVTILNWSFPRK 580

Query: 1789 DQPRFETCYQIALAIKKEVEDLEAGGIQVIQIDEAALREGLPLRKSEHAFYLDWAVHSFR 1968
            D  R     Q+ LA+++EV  LEA G  +IQ+D+ ALREGLPL     A YL WAV +FR
Sbjct: 581  DISRAAQAMQLGLALRQEVAALEAAGCTIIQVDDPALREGLPLNGERWASYLSWAVDAFR 640

Query: 1969 ITNCGVQDTTQIHTHMCYSNFNDIIQSIINMDADVITIENSRSDEKLLSVFREGVVYGAG 2148
            +        TQ+ TH+CYS+F DI+ +I  MDADV+TIENSRSD+ +++       YG  
Sbjct: 641  LCTGVAAAGTQVVTHLCYSDFQDILPAIDRMDADVLTIENSRSDKPMMAAL-AAAGYGRD 699

Query: 2149 IGPGVYDIHSPRIPSKEEIADRVNKMLAVLDTNIL-------WVNPDCGLKTRKYAEVKP 2307
            IGPGVYD+HSP +PS E I  R+    + +D+ IL       WVNPDCGLKTR + E   
Sbjct: 700  IGPGVYDVHSPVVPSVEFIKSRIR---SFVDSGILSGRYDRIWVNPDCGLKTRGWPETIA 756

Query: 2308 ALTNMVEAAKQIRAELAKA 2364
            AL NMVEAA Q RAEL  A
Sbjct: 757  ALANMVEAAAQARAELQLA 775

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>Q4JAI4:METE_SULAC Probable methylcobalamin:homocysteine methyltransferase - Sulfolobus|
            acidocaldarius
          Length = 339

 Score =  175 bits (443), Expect = 1e-42
 Identities = 107/336 (31%), Positives = 181/336 (53%), Gaps = 1/336 (0%)
 Frame = +1

Query: 1357 LPVLPTTTIGSFPQTVELRRVRREYKAKKISEEEYTNAIKEEISKVVKIQEELDIDVLVH 1536
            + +LPTT IGS+P+   LR   R ++A K+++E+   A  + +  VV+  +E  IDV   
Sbjct: 5    ITILPTTVIGSYPRPKWLRETIRLHRAGKVNQEDLEEAFNDAVVTVVRDHQEAGIDVPTD 64

Query: 1537 GEPERNDMVEYFGEQLSGFTFTANGWVQSYGSRCVKPPIIYGDVSRPNPMTVFWSKMAQS 1716
            GE  R++MVE+F E+LSGF F   G V+ +G    + P + G +   NPM +     A+S
Sbjct: 65   GEMRRDEMVEFFAERLSGFKF--YGHVRVWGDHYYRKPSVTGKIKYNNPMLLDEVNFAKS 122

Query: 1717 MT-ARPMKGMLTGPVTILNWSFVRNDQPRFETCYQIALAIKKEVEDLEAGGIQVIQIDEA 1893
            ++  + +K  +TGP TI  WS+    + + +  + +A  I +E+++L   GI+VIQ+DE 
Sbjct: 123  VSYTQNLKVTITGPYTISEWSYNEYYKTQRDMAFDLAKVINQEIKNLVDIGIKVIQVDEP 182

Query: 1894 ALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDTTQIHTHMCYSNFNDIIQSIINMDADV 2073
            A+      RK +    ++WA+ S   +  GV    ++  H+CY  ++ +   +  +  D 
Sbjct: 183  AIH----TRKED----VEWAIDSINESIKGV--NVKVVLHVCYGEYSYLEPHLDKLKVDQ 232

Query: 2074 ITIENSRSDEKLLSVFREGVVYGAGIGPGVYDIHSPRIPSKEEIADRVNKMLAVLDTNIL 2253
            I +     +   + +F++   +   IG GV D+H+ +I S EE+A+ + K+L      ++
Sbjct: 233  INLALKNYNYTPVKLFKK---WDREIGVGVIDVHNRKIESVEEVAEDLRKLLEYFKPEMV 289

Query: 2254 WVNPDCGLKTRKYAEVKPALTNMVEAAKQIRAELAK 2361
            WVNPDCGLK          L NMV+    +R EL K
Sbjct: 290  WVNPDCGLKLLPRKIALQKLINMVKGTLIVREELKK 325

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>Q975N4:METE_SULTO Probable methylcobalamin:homocysteine methyltransferase - Sulfolobus|
            tokodaii
          Length = 338

 Score =  168 bits (425), Expect = 1e-40
 Identities = 107/336 (31%), Positives = 178/336 (52%), Gaps = 3/336 (0%)
 Frame = +1

Query: 1357 LPVLPTTTIGSFPQTVELRRVRREYKAKKISEEEYTNAIKEEISKVVKIQEELDIDVLVH 1536
            LP+LPTT IGS+P+   LR   R +KA KIS+E+   A  + +  V+   E   +DV   
Sbjct: 4    LPILPTTVIGSYPRPKWLREAIRLHKAGKISDEDLQEAFDDAVVTVLHDHEIAGVDVPTD 63

Query: 1537 GEPERNDMVEYFGEQLSGFTFTANGWVQSYGSRCVKPPIIYGDVSRPNPMTVFWSKMAQS 1716
            GE  R++MVE+F E+L+GF F   G V+ +G+   + P +   V    PM V     A+S
Sbjct: 64   GEMRRDEMVEFFAERLAGFKF--YGPVRVWGTNYYRKPSVVSKVEYIKPMLVDEFLFAKS 121

Query: 1717 MT-ARPMKGMLTGPVTILNWSFVRNDQPRFETCYQIALAIKKEVEDLEAGGIQVIQIDEA 1893
            ++    +K  +TGP TI  WS+    + + +  + +A  I  E++ L   G ++IQ+DE 
Sbjct: 122  VSYTENLKITITGPYTIAEWSYNEYYKSKKDLAFDLAKVINSEMKKLVEAGAKIIQVDEP 181

Query: 1894 ALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDTTQIHTHMCYSNFNDIIQSIINMDADV 2073
            A+          H   ++WA+ +   +  G+    ++  H+CY  ++ +   +  ++ D 
Sbjct: 182  AIH--------THKNEVEWAIEAVNESIKGI--NVKVVMHVCYGEYSYLEPYLDKLNVDQ 231

Query: 2074 ITIENSRSDEKLLSVFREGVVYGAGIGPGVYDIHSPRIPSKEEIADRVNKMLAVLDTNIL 2253
            I +     + + + +F++   +   IG GV D+H+ RI + EE+A+ +  +L      ++
Sbjct: 232  INLALKNYNYEPVKLFKK---WDREIGVGVIDVHNKRIETPEEVANDLKMLLDYFKPEMI 288

Query: 2254 WVNPDCGLK--TRKYAEVKPALTNMVEAAKQIRAEL 2355
            WVNPDCGLK   RK A  K  L NMV+  K +R EL
Sbjct: 289  WVNPDCGLKLLPRKIAFQK--LLNMVKGTKIVREEL 322

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>Q980A9:METE_SULSO Probable methylcobalamin:homocysteine methyltransferase - Sulfolobus|
            solfataricus
          Length = 332

 Score =  161 bits (408), Expect = 1e-38
 Identities = 106/338 (31%), Positives = 177/338 (52%), Gaps = 3/338 (0%)
 Frame = +1

Query: 1357 LPVLPTTTIGSFPQTVELRRVRREYKAKKISEEEYTNAIKEEISKVVKIQEELDIDVLVH 1536
            LP+LPTT IGS+P+   LR   R +KA K+S E+   A  + +  V +   +  +DV   
Sbjct: 4    LPLLPTTVIGSYPRPKWLRESIRLHKAGKMSNEDLQEAFNDAVIAVFQDHYKAGVDVPTD 63

Query: 1537 GEPERNDMVEYFGEQLSGFTFTANGWVQSYGSRCVKPPIIYGDVSRPNPMTVFWSKMAQS 1716
            GE  R++MVE+F E++ GF F   G V+ +G+   + P +   +    PM V     A+S
Sbjct: 64   GEVRRDEMVEFFAERIKGFKF--YGPVRVWGTAYYRKPSVVSKIEYREPMLVDEFTFAKS 121

Query: 1717 MT-ARPMKGMLTGPVTILNWSFVRNDQPRFETCYQIALAIKKEVEDLEAGGIQVIQIDEA 1893
            ++    +K  +TGP TI  WS+    + + +  + +A AI +E+++L   G ++IQIDE 
Sbjct: 122  VSYTDNLKITITGPYTIAEWSYNEYYRNKKDLVFDLAKAINQEIKNLVEAGAKIIQIDEP 181

Query: 1894 ALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDTTQIHTHMCYSNFNDIIQSIINMDADV 2073
            AL      RK +    + W V +      GV    ++  H+CY +++ +      +  D 
Sbjct: 182  ALH----TRKED----VSWGVEAVNEAVKGV--NAKLVMHICYGDYSFVAPYFNEIKVDQ 231

Query: 2074 ITIENSRSDEKLLSVFREGVVYGAGIGPGVYDIHSPRIPSKEEIADRVNKMLAVLDTNIL 2253
            I       + K L + ++   +   +G GV D+H+ ++ + EE+A+ + K+L       +
Sbjct: 232  INFALKIYNYKPLELLKK-YGFDKELGAGVVDVHNRKVETSEEVANDIRKILEYFPPEKV 290

Query: 2254 WVNPDCGLK--TRKYAEVKPALTNMVEAAKQIRAELAK 2361
            W+NPDCGLK  +RK A  K  L +MVE  K +R EL +
Sbjct: 291  WINPDCGLKLLSRKIAYQK--LVSMVEGTKVVREELKR 326

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>Q9YA91:METE_AERPE Probable methylcobalamin:homocysteine methyltransferase - Aeropyrum|
            pernix
          Length = 332

 Score =  157 bits (397), Expect = 2e-37
 Identities = 109/331 (32%), Positives = 176/331 (53%), Gaps = 3/331 (0%)
 Frame = +1

Query: 1369 PTTTIGSFPQTVELRRVRREYKAKKISEEEYTNAIKEEISKVVKIQEELDIDVLVHGEPE 1548
            PTT +GS+P+        ++ +A +ISEEE+    +E I  VV+      +D++  GE  
Sbjct: 12   PTTVVGSYPKIGPASEAIKKRRAGEISEEEFHRIARESIRMVVEDYIWAGVDIISDGEQT 71

Query: 1549 RNDMVEYFGEQLSGFTFTANGWVQSYGSRCVKPPIIYGDVSRPNPMTVFWSKMAQSMTA- 1725
            R DMV YF E+L G  +    WV+ + +   + PI+ G V    PM +   + A+S++A 
Sbjct: 72   REDMVVYFAERLEG--YREGDWVRVFDNVYFRKPIVAGRVRWVRPMIIEDWEYARSISAG 129

Query: 1726 RPMKGMLTGPVTILNWSFVRNDQPRFETCYQIALAIKKEVEDLEAGGIQVIQIDEAALRE 1905
            RP+K ++TGP T+L WSF  +   R E  + +A AI++E+++  A G + IQ+DE AL  
Sbjct: 130  RPVKFIITGPYTMLEWSFDLHYGDRRELIFDLARAIRREIDEALARGAEYIQVDEPAL-S 188

Query: 1906 GLPLRKSEHAFYLDWAVHSFRITNCGVQDTTQIHTHMCYSNFNDIIQSIINMDADVITIE 2085
              P +  E A  L  A+    I   GV     +  H+CY     I+  I++   D   +E
Sbjct: 189  TRPFK--EEAELLKEALD---IIFKGVGAKRIV--HICYGELERILPYILDYPVDQFDLE 241

Query: 2086 NSRSDEKLLSVFREGVVYGAGIGPGVYDIHSPRIPSKEEIADRVNKMLA--VLDTNILWV 2259
               S+ +LL   +E   Y   IG GV D+HS ++ S  E+ + +++++   ++    ++V
Sbjct: 242  MKNSNFRLLPYLKE-YGYDKEIGYGVIDVHSFQVESVGEVKEAIDRLMKMDIVGPEKVYV 300

Query: 2260 NPDCGLKTRKYAEVKPALTNMVEAAKQIRAE 2352
            +PDCGLK       +  L NMVEAA+  R E
Sbjct: 301  DPDCGLKRLPRDVARAKLKNMVEAARLAREE 331

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>Q8TH63:METE_PYRFU Probable methylcobalamin:homocysteine methyltransferase - Pyrococcus|
            furiosus
          Length = 338

 Score =  145 bits (366), Expect = 9e-34
 Identities = 101/342 (29%), Positives = 170/342 (49%), Gaps = 5/342 (1%)
 Frame = +1

Query: 1351 LNLPVLPTTTIGSFPQTVELRRVRREYKAKKISEEEYTNAIKEEISKVVKIQEELDIDVL 1530
            + LP+LPT+ IGS+P+   L R+ +  +  KI EE++  A+++    V++  E   ID+ 
Sbjct: 1    MELPILPTSVIGSYPKPRWLLRMYKLRELGKIPEEDFKEAVRDASISVLREHERAGIDIP 60

Query: 1531 VHGEPERNDMVEYFGEQLSGFTFTANGWVQSYGSRCVKPPIIYGDVSRPNPMTV---FWS 1701
              GE  R++M EYF  ++ GF F   G V+ +G+           +    P+ +    W 
Sbjct: 61   WDGEMGRSEMTEYFTSKIKGFKF--YGPVRVWGNAYFNKAAAVDKLEYEEPLVLDEFLWV 118

Query: 1702 KMAQSMTARPMKGMLTGPVTILNWSFVRNDQPRFETCYQIALAIKKEVEDLEAGGIQVIQ 1881
            K  ++ T   +K  +TGP TI  WSF      +      +A  I KE++ LE  G + +Q
Sbjct: 119  K--ENTTREIVKIPITGPYTIAEWSFNEYYPDKESFVMDLAEIINKELKVLEKHGAKFVQ 176

Query: 1882 IDEAALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDTTQIHTHMCYSNFNDIIQSIINM 2061
            +DE A+          H   +  AV +      G++   ++  H+CYSN+N +      +
Sbjct: 177  LDEPAM--------LNHPSEVPLAVDAINRAVKGIK--MKVGLHVCYSNYNLLADYFDEI 226

Query: 2062 DADVITIENSRSDEKLLSVFREGVVYGAGIGPGVYDIHSPRIPSKEEIADRVNKMLAVLD 2241
                  +E +  + + +   ++  +    +G GV D+H+PR+ S EEI   + K+   L+
Sbjct: 227  KVTQFALEFANRNFRDMDFLKK--LSNKELGFGVVDVHNPRVESVEEIRQAIKKVFTYLE 284

Query: 2242 TNILWVNPDCGLK--TRKYAEVKPALTNMVEAAKQIRAELAK 2361
               +++NPDCGLK   RK A  K  L NMV+A + +R EL K
Sbjct: 285  PEWVYINPDCGLKLLDRKIAYQK--LVNMVQAVRGVRKELEK 324

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>Q5JH51:METE_PYRKO Probable methylcobalamin:homocysteine methyltransferase - Pyrococcus|
            kodakaraensis (Thermococcus kodakaraensis)
          Length = 336

 Score =  142 bits (359), Expect = 6e-33
 Identities = 95/338 (28%), Positives = 166/338 (49%), Gaps = 1/338 (0%)
 Frame = +1

Query: 1351 LNLPVLPTTTIGSFPQTVELRRVRREYKAKKISEEEYTNAIKEEISKVVKIQEELDIDVL 1530
            + LP+LPT+ IGS+P+   L R+    +  ++ EE++  A+++    V++  E   ID+ 
Sbjct: 1    MELPILPTSIIGSYPKPRWLLRMYNLRELGRLPEEDFREAVRDASVAVLREHERAGIDIP 60

Query: 1531 VHGEPERNDMVEYFGEQLSGFTFTANGWVQSYGSRCVKPPIIYGDVSRPNPMTVFWSKMA 1710
              GE  R++M EYF  +++GF F   G ++ +G+           +    P+ +   +  
Sbjct: 61   WDGEMGRSEMTEYFTAKIAGFKFY--GPIRVWGNAYFNKAAAVSKLEYREPLVLDEFRWV 118

Query: 1711 QSMTARPM-KGMLTGPVTILNWSFVRNDQPRFETCYQIALAIKKEVEDLEAGGIQVIQID 1887
            +  T R + K  +TGP TI  WSF      + E  + +A  + KE + LE  G   IQID
Sbjct: 119  KENTTREIIKVPITGPYTIAEWSFNEYYSSKEELAFDLAKILNKEFKLLEKEGATFIQID 178

Query: 1888 EAALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDTTQIHTHMCYSNFNDIIQSIINMDA 2067
            E A+          H   +  AV +      GV+   +   H+CYSN+  +     ++  
Sbjct: 179  EPAMLN--------HPDEVSIAVEAINRAVKGVK--VKFGLHVCYSNYYLLADYFDDIKV 228

Query: 2068 DVITIENSRSDEKLLSVFREGVVYGAGIGPGVYDIHSPRIPSKEEIADRVNKMLAVLDTN 2247
                +E +  + + L   ++  +    +G GV D+H+PR+ S EE+A  + K++  ++  
Sbjct: 229  SQFALEAANRNFRDLDYLKK--LTHQELGFGVVDVHNPRVESPEEVAKAIRKVMEYIEPE 286

Query: 2248 ILWVNPDCGLKTRKYAEVKPALTNMVEAAKQIRAELAK 2361
             L++NPDCGLK          L NMV+  + +R ELA+
Sbjct: 287  RLYINPDCGLKLLDRRIAYQKLVNMVKGVEIVRRELAR 324

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>Q9V085:METE_PYRAB Probable methylcobalamin:homocysteine methyltransferase - Pyrococcus|
            abyssi
          Length = 338

 Score =  139 bits (351), Expect = 5e-32
 Identities = 97/340 (28%), Positives = 165/340 (48%), Gaps = 3/340 (0%)
 Frame = +1

Query: 1351 LNLPVLPTTTIGSFPQTVELRRVRREYKAKKISEEEYTNAIKEEISKVVKIQEELDIDVL 1530
            + LP+LPT+ IGS+P+   L R+ +  +  KI EE++  A+K+    V++  E   +D+ 
Sbjct: 1    MELPILPTSVIGSYPKPRWLLRMYKLRELGKIPEEDFKEAVKDASVAVLREHERAGVDIP 60

Query: 1531 VHGEPERNDMVEYFGEQLSGFTFTANGWVQSYGSRCVKPPIIYGDVSRPNPMTV---FWS 1701
              GE  R++M E+F  ++SGF F   G V+ +G+           +    P+ +    W 
Sbjct: 61   WDGEMWRSEMTEHFTAKISGFKF--YGPVRVWGNAYFNKAAAVDKLEYKEPLVLEEFLW- 117

Query: 1702 KMAQSMTARPMKGMLTGPVTILNWSFVRNDQPRFETCYQIALAIKKEVEDLEAGGIQVIQ 1881
             + ++ T   +K  +TGP TI  WSF      +      +A  I KE++ LE  G   IQ
Sbjct: 118  -VRENTTREIVKVPITGPYTIAEWSFNEYYPDKESFVMDLAKIINKELKTLEEHGATYIQ 176

Query: 1882 IDEAALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDTTQIHTHMCYSNFNDIIQSIINM 2061
            +DE A+          H   +  AV +      G++   ++  H+CYSN+  +     ++
Sbjct: 177  LDEPAM--------LNHPDEVPLAVEAINRAVKGIK--IKVGLHVCYSNYYLLADYFDDI 226

Query: 2062 DADVITIENSRSDEKLLSVFREGVVYGAGIGPGVYDIHSPRIPSKEEIADRVNKMLAVLD 2241
                  +E +    + +   ++  + G  +G GV D+H+PRI + +EI   + K    L+
Sbjct: 227  RVTQFALEFANRQFRDMDFLKK--LSGKELGFGVVDVHNPRIETVDEIVRAIKKAFNYLE 284

Query: 2242 TNILWVNPDCGLKTRKYAEVKPALTNMVEAAKQIRAELAK 2361
               L++NPDCGLK          L NMV+A + +R EL K
Sbjct: 285  PEWLYINPDCGLKLLDRRIAYQKLVNMVKAVRIVRKELEK 324

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>O58816:METE_PYRHO Probable methylcobalamin:homocysteine methyltransferase - Pyrococcus|
            horikoshii
          Length = 338

 Score =  137 bits (344), Expect = 3e-31
 Identities = 96/340 (28%), Positives = 162/340 (47%), Gaps = 3/340 (0%)
 Frame = +1

Query: 1351 LNLPVLPTTTIGSFPQTVELRRVRREYKAKKISEEEYTNAIKEEISKVVKIQEELDIDVL 1530
            + LP+LPT+ IGS+P+   L R+ R     KI EE++  A+K+    V++  E   +D+ 
Sbjct: 1    MELPILPTSVIGSYPKPRWLLRMYRLRDLGKIPEEDFKEAVKDASVSVLREHERAGVDIP 60

Query: 1531 VHGEPERNDMVEYFGEQLSGFTFTANGWVQSYGSRCVKPPIIYGDVSRPNPMTV---FWS 1701
              GE  R +M E+F  ++ GF F   G V+ +G+           +    P+ +    W 
Sbjct: 61   WDGEMWRTEMTEHFTAKIGGFKF--YGPVRVWGNAYFNKAAAVDKLEYKEPLVLEEFLWV 118

Query: 1702 KMAQSMTARPMKGMLTGPVTILNWSFVRNDQPRFETCYQIALAIKKEVEDLEAGGIQVIQ 1881
            K  ++ T   +K  +TGP TI  WSF      +      +A  I KE++ LE  G   IQ
Sbjct: 119  K--KNTTREVVKIPITGPYTIAEWSFNEYYPDKESFIMDLAKIINKELKMLENHGALYIQ 176

Query: 1882 IDEAALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDTTQIHTHMCYSNFNDIIQSIINM 2061
            +DE A+          H   +  AV +      G++   ++  H+CYSN+  +      +
Sbjct: 177  LDEPAM--------LNHPDEVPLAVEAINKAVKGIK--IKVGLHVCYSNYYLLADYFDEI 226

Query: 2062 DADVITIENSRSDEKLLSVFREGVVYGAGIGPGVYDIHSPRIPSKEEIADRVNKMLAVLD 2241
                  +E +    + +   ++  +    +G GV D+H+PRI S EEI   + K+   ++
Sbjct: 227  RVTQFALEFANRQFRDMDFLKK--LSNKELGFGVVDVHNPRIESVEEIVKAIKKVFEYVE 284

Query: 2242 TNILWVNPDCGLKTRKYAEVKPALTNMVEAAKQIRAELAK 2361
              +L++NPDCG+K          L NMV+A + +R EL +
Sbjct: 285  PELLYINPDCGMKLLDRNIAYNKLVNMVKATELVRKELER 324

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>P57704:METE_THEAC Probable methylcobalamin:homocysteine methyltransferase -|
            Thermoplasma acidophilum
          Length = 343

 Score =  100 bits (250), Expect = 2e-20
 Identities = 98/363 (26%), Positives = 158/363 (43%), Gaps = 30/363 (8%)
 Frame = +1

Query: 1357 LPVLPTTTIGSFPQTVELRRVRREYKAKKISEEE----YTNAIKEEISKVVKIQEELDID 1524
            +  L T  IGSF +         +Y AK+  + E    +T   +    + +++ E   +D
Sbjct: 1    MTALITQEIGSFRKP--------DYLAKEFHKIERTPKFTELAERATRETLEVFERSGLD 52

Query: 1525 VL-VHGEPERNDMVEYFGEQLSGFTFTANGWVQSYGSRCVKPPIIYGDVSRPNPMTVFWS 1701
             + + GE  R +M E+  E++ G  F   G V+S+ +R  +       + R  P  V   
Sbjct: 53   NIGIGGEMFRWEMYEHPAERIKGIIFY--GMVRSFDNRYYRKGSAIDRLERREPFHVDEV 110

Query: 1702 KMAQSMTARPMKGMLTGPVTILNWSFVRNDQPRFETCYQIALAIKKEVEDLEAGGIQV-- 1875
            K     T +P+K  +TGP T++ WSF      R +   + A  I +E++D+ +   QV  
Sbjct: 111  KFVAGTTKKPLKVPITGPYTMMEWSFNDYYDSREDLAMEFARIINEELKDIASVWKQVSG 170

Query: 1876 -----IQIDEAALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDTTQIHTHMCY-SNFND 2037
                 IQIDE A         + H   +D  V S   +  GV    +I  H+CY S++  
Sbjct: 171  GRRLEIQIDEPA--------TTTHPDEMDIVVDSINRSVQGVDG--EISMHVCYSSDYRL 220

Query: 2038 IIQSIINMDADVITIENSRSDE----------------KLLSVFREGVVYGAGIGPGVYD 2169
            +   I ++  D   +E S  D                 K  +   E +     IG GV D
Sbjct: 221  LYDRIPDLKIDGYNLEYSNRDTLERGLTDDKRVGFQDLKYFAQINESLQRKKFIGIGVTD 280

Query: 2170 IHSPRIPSKEEIADRVNKMLAVL-DTNILWVNPDCGLKTRKYAEVKPALTNMVEAAKQIR 2346
            +H   +   E I DR+N  L ++ D +++ +NPDCGL+TR     +  L NMV A   I 
Sbjct: 281  VHIDYVEPVELIEDRINYALKIIGDPDLVRINPDCGLRTRSREIGEQKLRNMVMARNNIL 340

Query: 2347 AEL 2355
             +L
Sbjct: 341  KQL 343

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>Q979L4:METE_THEVO Probable methylcobalamin:homocysteine methyltransferase -|
            Thermoplasma volcanium
          Length = 344

 Score = 95.5 bits (236), Expect = 1e-18
 Identities = 91/364 (25%), Positives = 162/364 (44%), Gaps = 30/364 (8%)
 Frame = +1

Query: 1357 LPVLPTTTIGSFPQ----TVELRRVRREYKAKKISEEEYTNAIKEEISKVVKIQEELDID 1524
            +  L T  IGSF +    ++E  ++    K K+++E    + +K        I E   +D
Sbjct: 1    MAALITQEIGSFRKPEYLSMEFHKIEGTEKFKELAERATIDTLK--------IFENTGLD 52

Query: 1525 -VLVHGEPERNDMVEYFGEQLSGFTFTANGWVQSYGSRCVKPPIIYGDVSRPNPMTVFWS 1701
             V + GE  R +M E+  E++ G  F   G V+S+ +R  +   +   + R     +   
Sbjct: 53   NVGIGGEMYRWEMYEHPAERIKGLIFY--GMVRSFDNRYYRKGSVIDKIERRGSFHMDEV 110

Query: 1702 KMAQSMTARPMKGMLTGPVTILNWSFVRNDQPRFETCYQIALAIKKEVEDLEA------- 1860
            +     T +P+K  +TGP T+++WSF  +   R E   + A  I +E++++++       
Sbjct: 111  EFVAKSTKKPIKIPITGPYTMMDWSFNDHYNDRHELAMEFARIINEELKEIQSKWPYISN 170

Query: 1861 GGIQVIQIDEAALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDTTQIHTHMCYS----- 2025
            G    IQIDE A         + H   +D  V S   +  G+    ++  H+CYS     
Sbjct: 171  GRKLEIQIDEPA--------TTTHPDEMDIVVDSVNKSIEGID--AELSLHVCYSRDYRL 220

Query: 2026 --------NFNDIIQSIINMDADVITIENSR----SDEKLLSVFREGVVYGAGIGPGVYD 2169
                    N +       N D   + +E+++     D K  +   E +     IG GV D
Sbjct: 221  LYDRIPELNIDGYNLEYSNRDTTDLGVEDAKRPGFQDIKYFNEVNESLQRKKFIGVGVTD 280

Query: 2170 IHSPRIPSKEEIADRVNKMLAVL-DTNILWVNPDCGLKTRKYAEVKPALTNMVEAAKQIR 2346
            +H   I   + I DR+  +L ++ D  ++ +NPDCGL+TR  +  +  L NMV A   + 
Sbjct: 281  VHIDFIEPVKLIEDRIKYVLNIIKDPELVKLNPDCGLRTRSRSIGEQKLRNMVIAKNNVL 340

Query: 2347 AELA 2358
             +++
Sbjct: 341  KDIS 344

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>Q56837:XECA_XANP2 2-hydroxypropyl-CoM lyase - Xanthobacter sp. (strain Py2)|
          Length = 376

 Score = 78.6 bits (192), Expect = 1e-13
 Identities = 84/380 (22%), Positives = 159/380 (41%), Gaps = 46/380 (12%)
 Frame = +1

Query: 1366 LPTTTIGSFPQTVELRRVRREYKAKKISEEEYTNAIKEE-----ISKVVKIQEELDIDVL 1530
            +PT+ +G++P     R    ++      ++E  +A+ +E     ++ + + QE   +D++
Sbjct: 10   IPTSMVGNYPNP---RWWDAQFARTWTGDQEPPDALIQESLEDAVAAIARDQERAGLDII 66

Query: 1531 ----VHGEPERNDMVEYFGEQLSGFTFTANGWVQSYGSRCVKPPIIYGDVSRPNPMTVFW 1698
                VHG+      + Y+  +L G+            SR +    + G+V R   + V  
Sbjct: 67   SDGRVHGDNYAEQALYYYYRRL-GYDLKGGYLGFPIYSR-LHAGTLTGEVRRHGAIMVEQ 124

Query: 1699 SKMAQSMTARPMKGMLTGPVTILNWSFVRNDQPRFETCYQIALAIKKEVEDLEAGGIQVI 1878
            +K  +  T +P K   TG   +   +   + +   +    IA AI +++ +++A G+  I
Sbjct: 125  AKALKKATGKPTKVQYTGVQALTQATNDLHYKSSRDRAMAIAKAINEDIREVDALGVDFI 184

Query: 1879 QIDEAALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDTTQIHTHMCYSNFN-------- 2034
            QIDE               F+ DWA+ +F     GV++  +I  H+C+ N+         
Sbjct: 185  QIDEFTWPY----------FFEDWAIEAFNAAVDGVKNA-KIIAHVCWGNWGGTPAYYPD 233

Query: 2035 -------------------------DIIQSIINMDADVITIENS--RSDEK--LLSVFRE 2127
                                      I+        DV+ +E+   RSD+   L  +   
Sbjct: 234  ETAASGEIFDLTKRKAEATKATATGSIVPKAYEARLDVLNLESCGRRSDDLSGLHVMKNH 293

Query: 2128 GVVYGAGIGPGVYDIHSPRIPSKEEIADRVNKMLAVLDTNILWVNPDCGLKTRKYAEVKP 2307
             +        GV D+ S    + +E+A+R+ ++L ++  + L V  DCGL   +    + 
Sbjct: 294  PLPDNVSFWAGVIDVKSTITETADEVANRIRRLLEIVPADRLGVTTDCGLILLQRYIAQD 353

Query: 2308 ALTNMVEAAKQIRAELAKAQ 2367
             L  +VE  K +RAELAKA+
Sbjct: 354  KLHALVEGTKIVRAELAKAK 373

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>P55299:METE_METTM Probable methylcobalamin:homocysteine methyltransferase -|
            Methanobacterium thermoautotrophicum (strain Marburg /
            DSM 2133)
          Length = 309

 Score = 75.5 bits (184), Expect = 1e-12
 Identities = 76/329 (23%), Positives = 139/329 (42%), Gaps = 6/329 (1%)
 Frame = +1

Query: 1372 TTTIGSFPQTVELRRVRREYKAKKISEEEYTNAIKEEISKVVKIQEELDIDVLVHGEPER 1551
            TT +GS+P T       RE  +  I   +   A +  I   V+ Q    +D++  G+  R
Sbjct: 3    TTVVGSYPATPREPETLRERISSFIGSYD---ACRPAIETAVRDQVRAGVDIISDGQV-R 58

Query: 1552 NDMVEYFGEQLSGFTFTANGWVQSYGSRCVKPPIIYGDVSRPNPMTVFWSKMAQSMT--- 1722
             DMV +F E + G        V    SR   P    G +   +   ++  K+ + +T   
Sbjct: 59   GDMVGHFAEAMGGMM--VKDGVSIIFSRITPPA---GSIGSDD--LIYRIKILRKLTDDE 111

Query: 1723 ARPMKGMLTGPVTILNWSFVR---NDQPRFETCYQIALAIKKEVEDLEAGGIQVIQIDEA 1893
            ++ +KG++TGP T+ + S +    + Q R      +A A++ E E L+  G  +IQIDE 
Sbjct: 112  SKGVKGIITGPSTMAHASKIEGFYSPQKRERAIMDMADALRVEAEHLQDAGALMIQIDEP 171

Query: 1894 ALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDTTQIHTHMCYSNFNDIIQSIINMDADV 2073
             L  G+          +D       +          +  H+C  + + +I  ++    D+
Sbjct: 172  FLSTGM----------VDMGTARRAVKRISGALDVDVSLHVC-GDISGVIGELLTFPVDM 220

Query: 2074 ITIENSRSDEKLLSVFREGVVYGAGIGPGVYDIHSPRIPSKEEIADRVNKMLAVLDTNIL 2253
            + +E +     L  V  E       +G G  D  +  + S + I + + +   +   + L
Sbjct: 221  LDLEFAGRPSNL-EVLAEKWRGDKKLGFGCVDTSTEVVESTDTIKNLIERGADIAGEDNL 279

Query: 2254 WVNPDCGLKTRKYAEVKPALTNMVEAAKQ 2340
            +++PDCG++          L NMV+AA +
Sbjct: 280  YIDPDCGMRKLPREAAFSKLRNMVKAASE 308

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>O26869:METE_METTH Probable methylcobalamin:homocysteine methyltransferase -|
            Methanobacterium thermoautotrophicum
          Length = 308

 Score = 72.8 bits (177), Expect = 7e-12
 Identities = 78/328 (23%), Positives = 139/328 (42%), Gaps = 7/328 (2%)
 Frame = +1

Query: 1372 TTTIGSFPQTVELRRVRREYKAKKI-SEEEYTNAIKEEISKVVKIQEELDIDVLVHGEPE 1548
            TT +GS+P          E       S + Y  AI+      V+ Q    +D++  G+  
Sbjct: 3    TTVVGSYPTEPRGPETLGERLLNFFGSYDRYRPAIEA----AVRDQFRAGVDIISDGQV- 57

Query: 1549 RNDMVEYFGEQLSGFTFTANGWVQSYGSRCVKPPIIYGDVSRPNPMTVFWSKMAQSMT-- 1722
            R DMV +F   + G     +G    Y    + PP   G +   +    +  ++ + +T  
Sbjct: 58   RGDMVGHFAAAIGGMKIE-DGTSIIYSR--ITPPA--GSIGAADLRYAY--RILRGLTDD 110

Query: 1723 -ARPMKGMLTGPVTILNWSFVR---NDQPRFETCYQIALAIKKEVEDLEAGGIQVIQIDE 1890
             +R +KG++TGP T++  S +    + Q R      +A  +K E + L+  G  +IQIDE
Sbjct: 111  ESRGVKGIITGPSTMIYASRIEGFYDPQKRDRAVMDMAGVLKIEAKHLQDAGAAMIQIDE 170

Query: 1891 AALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDTTQIHTHMCYSNFNDIIQSIINMDAD 2070
              L  G+          +D       I +       ++  H+C  +  +++  ++    D
Sbjct: 171  PFLSTGI----------VDMKTAGRAIDHIAAGLDIEVSLHVC-GDIRNVLSDLLRFKVD 219

Query: 2071 VITIENSRSDEKLLSVFREGVVYGAGIGPGVYDIHSPRIPSKEEIADRVNKMLAVLDTNI 2250
            V+ +E +     L  V  E      G+G G  D  + R+ S EEI + + +   ++    
Sbjct: 220  VLDLEFAGRPSNL-EVLEEKWRGDKGVGFGCVDTTTERVESMEEIRNLIKRGADIVGEEN 278

Query: 2251 LWVNPDCGLKTRKYAEVKPALTNMVEAA 2334
            L+++PDCG++          L NMV AA
Sbjct: 279  LYIDPDCGMRKLPRKAAFSKLRNMVMAA 306

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>Q58868:METE_METJA Probable methylcobalamin:homocysteine methyltransferase -|
            Methanococcus jannaschii
          Length = 308

 Score = 72.4 bits (176), Expect = 9e-12
 Identities = 90/342 (26%), Positives = 148/342 (43%), Gaps = 17/342 (4%)
 Frame = +1

Query: 1372 TTTIGSFPQTVELRRVRREYKAKKISEEEYTNAIKEEISKVVKIQEELDIDVLVHGEPER 1551
            TT +GS+P   +      + K      +EY  AI+    + VK Q +  ++++  G+  R
Sbjct: 3    TTVVGSYPVVKKEETFLDKVKKVFGLYDEYKYAIE----RAVKDQVKAGVNIISDGQV-R 57

Query: 1552 NDMVEYFGEQLSGFTFTANGWVQSYGSRCVKPPIIYGDVSRPNPMTVFWSKMAQSMTAR- 1728
             DMVE F   + GF           G R V      G V    P+T+     A+S+  + 
Sbjct: 58   GDMVEIFTNNMYGFD----------GKRVV------GRVEFIKPITLKDILYAKSIAKKL 101

Query: 1729 ----PMKGMLTGPVTILNWSFVRN---DQPRFETCYQIALAIKKEVEDLEAGGIQVIQID 1887
                 +KG++TGP TI +   V +   D       Y IA A++KEVE L+   + +IQID
Sbjct: 102  NPNVEIKGIITGPCTIASSVRVESCYSDNRDENLIYDIAKALRKEVEALKKH-VPIIQID 160

Query: 1888 EAALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDTTQIHTHMCYSNFNDIIQSIINMDA 2067
            E  L  G+        +  D A  +  I   G+    +   H+C + +N II  +   + 
Sbjct: 161  EPILSTGM--------YDFDVARKAIDIIVDGLN--IKFAMHVCGNVYN-IIDELNKFNV 209

Query: 2068 DVITIENSRSDEKLLSVFREGVVYGAGIGPGVYDIHSPRIPSKEEIADRVNKMLAVLDTN 2247
            D++  E + + + L  V  E +    G G    +    ++ S EEI   + + + +L  N
Sbjct: 210  DILDHEFASNKKNL--VILESMEKKVGFG--CVNTKVKKVESVEEIKSLIEEGIEILKNN 265

Query: 2248 I---------LWVNPDCGLKTRKYAEVKPALTNMVEAAKQIR 2346
                      + ++PDCG++          L NMVEA K I+
Sbjct: 266  EKLNKNLSDNILIDPDCGMRLLPIDVAFNKLKNMVEATKLIK 307

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>Q6XPR3:RPTN_HUMAN Repetin - Homo sapiens (Human)|
          Length = 784

 Score = 36.6 bits (83), Expect = 0.56
 Identities = 34/133 (25%), Positives = 50/133 (37%), Gaps = 3/133 (2%)
 Frame = +3

Query: 1971 HQLWCPGHDPDPHPHVLL-QLQRHHPVHHQHGRRCDHH*ELAVRREASLRLPRGCGVRCW 2147
            HQ+W P  D   H H LL Q+Q+  P+ H+ GR           R+A  R   G G+  W
Sbjct: 646  HQVWEPEEDSQHHQHKLLAQIQQERPLCHK-GRDWQSCSSEQGHRQAQTRQSHGEGLSHW 704

Query: 2148 --HWPGRVRHPLPQDPVQGGDCRPRQQDARCARHQHPLGEPRLRSQDPQVRRGQARPHQH 2321
                 G           Q G C  + +        H   + +    +   +R   + H+ 
Sbjct: 705  AEEEQGHQTWDRHSHESQEGPCGTQDRRTHKDEQNHQRRDRQTHEHEQSHQRRDRQTHED 764

Query: 2322 GRGRQADPRRARQ 2360
             + RQ   RR RQ
Sbjct: 765  KQNRQ---RRDRQ 774

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>O06458:TRES_THETH Trehalose synthase - Thermus thermophilus|
          Length = 963

 Score = 36.6 bits (83), Expect = 0.56
 Identities = 47/154 (30%), Positives = 62/154 (40%), Gaps = 8/154 (5%)
 Frame = +1

Query: 754  ELESTLSGLNVLVETYFADVPAESYKTLTSLSSVTAYGFDLERGTKTLELVKSGF----- 918
            E E  L   N+   T   D+P E+Y+ L  +   +   F    G   L L   GF     
Sbjct: 478  EGERVLVVANLSRYTQAFDLPLEAYQGLVPVELFSQQPFPPVEGRYRLTLGPHGFALFAL 537

Query: 919  -PAGKYLFAGVVDGRYIWADDLAASLATLQSLEAIVGKDKLVVSTSCSLMHTA--VDLVN 1089
             P    L     D    WA++ A   A L  +    G + L+V T   L+H     +L+N
Sbjct: 538  KPVEAVLHLPSPD----WAEEPAPEEADLPRVHMPGGPEVLLVDT---LVHERGREELLN 590

Query: 1090 ETKLDDEIKSWLAFAAQKVVEVNALAKALAGQKD 1191
                  + KSWLA   QKV    AL  AL  QKD
Sbjct: 591  ALAQTLKEKSWLALKPQKV----ALLDALRFQKD 620

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>P21561:YGY3_HALSQ Hypothetical 50.6 kDa protein in the 5'region of gyrA and gyrB -|
            Haloferax sp. (strain Aa 2.2)
          Length = 437

 Score = 35.4 bits (80), Expect = 1.2
 Identities = 47/159 (29%), Positives = 61/159 (38%), Gaps = 28/159 (17%)
 Frame = +3

Query: 1986 PGHDPDPHPHVLLQLQRHHPVH----HQHGRRCDHH*E------------------LAVR 2099
            P H  + HP     + R  P H    H  GRR     +                  LA  
Sbjct: 210  PRHRRERHPPTARDVLRGEPGHGDGHHLEGRRGRPRPQGREAGRGAHPPQVRARIYLAAG 269

Query: 2100 REASLRLPRGCGVRCWHWPGRVR------HPLPQDPVQGGDCRPRQQDARCARHQHPLGE 2261
                L  PR  GVR  H  GR+R       P PQ P   GD  P+ +D+   R + P   
Sbjct: 270  EARGLPEPRPLGVRTVHRGGRLRGRVGQAGPRPQVP---GDFAPQGEDSE--RRETP--- 321

Query: 2262 PRLRSQDPQVRRGQARPHQHGRGRQADPRRARQGAVSSA 2378
            PR  S+    RR     H+H R R+   R  R+GA+ +A
Sbjct: 322  PRPHSRK---RRDTGAHHRHWRRRRRRVRH-REGALPAA 356

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>O13796:YKY1_SCHPO Uncharacterized protein C1142.01 - Schizosaccharomyces pombe (Fission|
            yeast)
          Length = 667

 Score = 35.0 bits (79), Expect = 1.6
 Identities = 24/80 (30%), Positives = 44/80 (55%)
 Frame = +1

Query: 2041 IQSIINMDADVITIENSRSDEKLLSVFREGVVYGAGIGPGVYDIHSPRIPSKEEIADRVN 2220
            ++S  N+D D+  IE + ++ KL    ++ V + AG+        S  IP  +E+ +++N
Sbjct: 130  LESSKNIDDDIDEIEKAAAELKLKYREQDQVEHVAGVE------ESATIPLDKELDEKLN 183

Query: 2221 KMLAVLDTNILWVNPDCGLK 2280
            K+L V   NI  +NPD  ++
Sbjct: 184  KLLGV---NISMLNPDLEIR 200

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>Q01613:SHRM1_XENLA Protein Shroom1 - Xenopus laevis (African clawed frog)|
          Length = 1420

 Score = 34.7 bits (78), Expect = 2.1
 Identities = 19/54 (35%), Positives = 28/54 (51%)
 Frame = -2

Query: 1050 GRYNKLVLPNNSLKRLKSGKRCSKVISPNVASIYNTSKKVLSSRETTLDKLKSL 889
            G YN +V  + S K   SG+  S + S N  S++ TS   L +  T LD  K++
Sbjct: 91   GVYNDIVSEHGSSKVALSGRSSSSLCSDNTTSVHRTSPAKLDNYVTNLDSEKNI 144

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>P53860:PDR16_YEAST Phosphatidylinositol transfer protein PDR16 - Saccharomyces|
            cerevisiae (Baker's yeast)
          Length = 351

 Score = 34.7 bits (78), Expect = 2.1
 Identities = 16/49 (32%), Positives = 25/49 (51%)
 Frame = -2

Query: 1797 RLVISDKRPVKDCDGACQHSLHWASSHALCHLGPEHGHRVGAAHVTIDN 1651
            R + + K  +KDC      +L W     + HLG EHG ++ A  V ++N
Sbjct: 92   RYLRATKWVLKDCIDRITMTLAWRREFGISHLGEEHGDKITADLVAVEN 140

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>P49244:FABH1_CUPWR 3-oxoacyl-[acyl-carrier-protein] synthase 3 A, chloroplast precursor|
            - Cuphea wrightii (Wright's waxweed)
          Length = 400

 Score = 34.7 bits (78), Expect = 2.1
 Identities = 31/120 (25%), Positives = 55/120 (45%), Gaps = 21/120 (17%)
 Frame = +1

Query: 2185 IPSKEEIADRVNKMLAVLDTNILWVNPDCGLKTRKYAEVKPALTNMVEAAKQIRAELAK- 2361
            IPS +   D + K   ++DTN  W++   G++ R+    K +LTN+   A +   E+A+ 
Sbjct: 76   IPSLQISNDDLAK---IVDTNDEWISVRTGIRNRRVLTGKDSLTNLASEAARKALEMAQI 132

Query: 2362 -AQ*AVLV--------------*QLSPPFNCKE-----DVTVAMAGVLL*IIWTSCPLVG 2481
             A    +V               Q+S    CK+     D+T A +G +L ++  +C + G
Sbjct: 133  DADDVDMVLMCTSTPEDLFGSAPQISKALGCKKNPLSYDITAACSGFVLGLVSAACHIRG 192

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>P11137:MAP2_HUMAN Microtubule-associated protein 2 - Homo sapiens (Human)|
          Length = 1827

 Score = 33.9 bits (76), Expect = 3.6
 Identities = 24/104 (23%), Positives = 43/104 (41%)
 Frame = +1

Query: 1792 QPRFETCYQIALAIKKEVEDLEAGGIQVIQIDEAALREGLPLRKSEHAFYLDWAVHSFRI 1971
            +P  ET       I+ E E++EA G    + D+   R                   + +I
Sbjct: 1219 EPLHETIVSEPAEIQSEEEEIEAQG----EYDKLLFRSD-----------------TLQI 1257

Query: 1972 TNCGVQDTTQIHTHMCYSNFNDIIQSIINMDADVITIENSRSDE 2103
            T+ GV    +     C S    +I+S++ ++ D IT+  + +DE
Sbjct: 1258 TDLGVSGAREEFVETCPSEHKGVIESVVTIEDDFITVVQTTTDE 1301

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>P21519:MAM_DROME Neurogenic protein mastermind - Drosophila melanogaster (Fruit fly)|
          Length = 1594

 Score = 33.9 bits (76), Expect = 3.6
 Identities = 16/42 (38%), Positives = 23/42 (54%)
 Frame = -1

Query: 976 HQPKCSVHLQHQQKGTFQQGNHS*QAQESWFHVRGQNHKQSR 851
           HQ    +HLQ QQ+   QQ  H+ QAQ+    V+ Q  +Q +
Sbjct: 38  HQQHLGLHLQQQQQLQLQQQQHNAQAQQQQIQVQQQQQQQQQ 79

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>Q7ZAN4:XERD_COREF Tyrosine recombinase xerD - Corynebacterium efficiens|
          Length = 304

 Score = 33.1 bits (74), Expect = 6.2
 Identities = 25/67 (37%), Positives = 36/67 (53%), Gaps = 4/67 (5%)
 Frame = -2

Query: 267 VVSEGVAGDVLDPSTSHLLPD--ACPEVGGNLLQILGAALAIPERLKGK--LELPLGAHA 100
           +V   VA DV  PST   LPD  + PEV   +  I  + +A P  ++ +  LE+  G  A
Sbjct: 96  LVGVDVAADVSPPSTGRHLPDTLSVPEVETLIDAIPTSDIATPVDIRDRALLEVLYGTGA 155

Query: 99  RVSDNVG 79
           R+S+ VG
Sbjct: 156 RISEAVG 162

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>Q8K1L0:CREB5_MOUSE cAMP response element-binding protein 5 - Mus musculus (Mouse)|
          Length = 357

 Score = 32.7 bits (73), Expect = 8.0
 Identities = 15/36 (41%), Positives = 17/36 (47%)
 Frame = +3

Query: 1971 HQLWCPGHDPDPHPHVLLQLQRHHPVHHQHGRRCDH 2078
            HQ   P H P P PH     Q++HP HH H     H
Sbjct: 141  HQHQHPAHHPHPQPH----HQQNHPHHHSHSHLHAH 172

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>Q02930:CREB5_HUMAN cAMP response element-binding protein 5 - Homo sapiens (Human)|
          Length = 508

 Score = 32.7 bits (73), Expect = 8.0
 Identities = 15/36 (41%), Positives = 17/36 (47%)
 Frame = +3

Query: 1971 HQLWCPGHDPDPHPHVLLQLQRHHPVHHQHGRRCDH 2078
            HQ   P H P P PH     Q++HP HH H     H
Sbjct: 292  HQHQHPAHHPHPQPH----HQQNHPHHHSHSHLHAH 323

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>Q4JWT3:PROA_CORJK Gamma-glutamyl phosphate reductase - Corynebacterium jeikeium|
           (strain K411)
          Length = 434

 Score = 32.7 bits (73), Expect = 8.0
 Identities = 21/67 (31%), Positives = 32/67 (47%), Gaps = 7/67 (10%)
 Frame = +1

Query: 229 GIKYIPSNTFAYYDQVLDTTAMLGAVPDRYSWT-------GGEINLSTYFSMARGNATVP 387
           GI      T +Y++Q +D  A+  ++    +WT       G EI +ST    ARG   +P
Sbjct: 360 GIAARDYKTTSYFEQYVDAAAV--SINTSTAWTDGEMFGFGAEIGISTQKLHARGPMGLP 417

Query: 388 AMEMTKW 408
            +  TKW
Sbjct: 418 ELTSTKW 424

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>P49245:FABH2_CUPWR 3-oxoacyl-[acyl-carrier-protein] synthase 3 B, chloroplast precursor|
            - Cuphea wrightii (Wright's waxweed)
          Length = 402

 Score = 32.7 bits (73), Expect = 8.0
 Identities = 25/104 (24%), Positives = 47/104 (45%), Gaps = 21/104 (20%)
 Frame = +1

Query: 2233 VLDTNILWVNPDCGLKTRKYAEVKPALTNMVEAAKQIRAELAKAQ----*AVLV------ 2382
            ++DTN  W++   G++ R+    K +LTN+   A +   E+A+        VL+      
Sbjct: 91   IVDTNDEWISVRTGIRNRRVLTGKESLTNLATVAARKALEMAQVDANDVDMVLMCTSTPE 150

Query: 2383 ------*QLSPPFNCKE-----DVTVAMAGVLL*IIWTSCPLVG 2481
                   Q+     CK+     D+T A +G +L ++  +C + G
Sbjct: 151  DLFGSAPQIQKALGCKKNPLAYDITAACSGFVLGLVSAACHIRG 194


  Database: uniprot_sprot.fasta.out
    Posted date:  Jul 19, 2007  5:58 PM
  Number of letters in database: 100,686,439
  Number of sequences in database:  274,295
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 274295
Number of Hits to DB: 452,100,772
Number of extensions: 10096344
Number of successful extensions: 34164
Number of sequences better than 10.0: 111
Number of HSP's gapped: 33505
Number of HSP's successfully gapped: 114
Length of query: 888
Length of database: 100,686,439
Length adjustment: 122
Effective length of query: 766
Effective length of database: 67,222,449
Effective search space: 51492395934
Effective search space used: 51492395934
Neighboring words threshold: 12
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)

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full-length cDNA and EST

Clone Information

BLAST Search Result