ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | FLbaf96e15 |
|---|---|
| Clone Library Name | barley_pub |
>P47997:G11A_ORYSA Protein kinase G11A - Oryza sativa (Rice)| Length = 589 Score = 468 bits (1203), Expect = e-131 Identities = 239/423 (56%), Positives = 288/423 (68%), Gaps = 13/423 (3%) Frame = +3 Query: 1278 RSQNSKSSISEYGC----STSISDESQFGLYGYNNRPHMVKDLCWITIRQLALQQGPLGL 1445 RS+ + S C S+ +SDES +PH D W I+ + + G LGL Sbjct: 133 RSETGERGFSSSRCRPSTSSDVSDESACSSISSVTKPHKANDSRWEAIQMIRTRDGILGL 192 Query: 1446 DNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEMLDH 1625 +F+LLK+LGCGDIG+VYL+EL + FA+KVMD L SRKK+LRAQ E+EIL+ LDH Sbjct: 193 SHFKLLKKLGCGDIGSVYLSELSGTKSYFAMKVMDKASLASRKKLLRAQTEKEILQCLDH 252 Query: 1626 PFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALEYLH 1805 PFLPTLY HF TD SCLVME+CPGGDLH LRQRQ G+ FPE + +FYVAE+LLA+EYLH Sbjct: 253 PFLPTLYTHFETDKFSCLVMEFCPGGDLHTLRQRQRGKYFPEQAVKFYVAEILLAMEYLH 312 Query: 1806 MLGVIYRDLKPENILVRDDGHIMLSDFDXXXXXXXXXXXXXXXXXXXNHQPKKLTSPCAE 1985 MLG+IYRDLKPEN+LVR+DGHIMLSDFD K + C + Sbjct: 313 MLGIIYRDLKPENVLVREDGHIMLSDFDLSLRCAVSPTLIRSSNPDAEALRKNNQAYCVQ 372 Query: 1986 SYCINSSC-LQPSCA-QTSCFXXXXXXXXXXXXXXXXXXXXQ------LVVEPTEARSNS 2141 C+ SC +QPSCA T+CF Q L+ EP++ARS S Sbjct: 373 PACVEPSCMIQPSCATPTTCFGPRFFSKSKKDRKPKPEVVNQVSPWPELIAEPSDARSMS 432 Query: 2142 FVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQNLRF 2321 FVGTHEYLAPEIIKG+GHGSAVDWWTFG+FLYELL+G+TPF+G GN TL NV+ Q LRF Sbjct: 433 FVGTHEYLAPEIIKGEGHGSAVDWWTFGIFLYELLFGKTPFKGSGNRATLFNVIGQPLRF 492 Query: 2322 PDNPVVSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPFFEGLNWALIRSVAPPET-RP 2498 P+ PVVS +A+DLIRGLLVKEP+ RLG RGA EIKQHPFFEG+NWALIR +PPE RP Sbjct: 493 PEYPVVSFSARDLIRGLLVKEPQQRLGCKRGATEIKQHPFFEGVNWALIRCASPPEVPRP 552 Query: 2499 CDV 2507 ++ Sbjct: 553 VEI 555
>P15792:KPK1_PHAVU Protein kinase PVPK-1 - Phaseolus vulgaris (Kidney bean) (French| bean) Length = 609 Score = 453 bits (1165), Expect = e-126 Identities = 242/456 (53%), Positives = 294/456 (64%), Gaps = 15/456 (3%) Frame = +3 Query: 1233 SDERSSEWLTLEKGERSQNSKSSISEYGCSTSISDESQFG-LYGYNNRPHMVKDLCWITI 1409 S ++S E + +++ K+SI + SDES L +PH D+ W I Sbjct: 155 SVDKSCESEVANSSDFNESRKTSICRASTGSDASDESSTSSLSSVLYKPHKANDIRWEAI 214 Query: 1410 RQLALQQGPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRA 1589 + + + G L + +FRLLK+LGCGDIG+VYLAEL + FA+KVM+ L +RKK+LRA Sbjct: 215 QAVRTRDGMLEMRHFRLLKKLGCGDIGSVYLAELSGTRTSFAMKVMNKTELANRKKLLRA 274 Query: 1590 QAEREILEMLDHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFY 1769 Q EREIL+ LDHPFLPTLY HF T+ SCLVME+CPGGDLH LRQRQPG+ F E + RFY Sbjct: 275 QTEREILQSLDHPFLPTLYTHFETEIFSCLVMEFCPGGDLHALRQRQPGKYFSEHAVRFY 334 Query: 1770 VAEVLLALEYLHMLGVIYRDLKPENILVRDDGHIMLSDFDXXXXXXXXXXXXXXXXXXXN 1949 VAEVLL+LEYLHMLG+IYRDLKPEN+LVR+DGHIMLSDFD N Sbjct: 335 VAEVLLSLEYLHMLGIIYRDLKPENVLVREDGHIMLSDFD----LSLRCSVSPTLVKSSN 390 Query: 1950 HQPKKLTSPCAESYCINSSC-LQPSCAQTSCF---------XXXXXXXXXXXXXXXXXXX 2099 + K + C + CI +C +QP C + SCF Sbjct: 391 NLQTKSSGYCVQPSCIEPTCVMQPDCIKPSCFTPRFLSGKSKKDKKSKPKNDMHNQVTPL 450 Query: 2100 XQLVVEPTEARSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGN 2279 +L+ EPT ARS SFVGTHEYLAPEIIKG+GHGSAVDWWTFG+FLYELL+GRTPF+G N Sbjct: 451 PELIAEPTNARSMSFVGTHEYLAPEIIKGEGHGSAVDWWTFGIFLYELLFGRTPFKGSAN 510 Query: 2280 DETLANVVSQNLRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPFFEGLNW 2459 TL NV+ Q LRFP++P VS A+DLIRGLLVKEP++RL RGA EIKQHPFF+ +NW Sbjct: 511 RATLFNVIGQPLRFPESPTVSFAARDLIRGLLVKEPQHRLAYRRGATEIKQHPFFQNVNW 570 Query: 2460 ALIRSVAPPETRPCDVVTLATVRK----KKEGKCLD 2555 ALIR PPE P V+ L K K G LD Sbjct: 571 ALIRCATPPEV-PRQVINLPQTEKDLGVKPSGNYLD 605
>Q05999:KPK7_ARATH Putative serine/threonine-protein kinase PK7 - Arabidopsis thaliana| (Mouse-ear cress) Length = 578 Score = 422 bits (1085), Expect = e-117 Identities = 224/399 (56%), Positives = 275/399 (68%), Gaps = 10/399 (2%) Frame = +3 Query: 1323 TSISDESQF-GLYGYNNRPHMVK-DLCWITIRQLALQQGP-LGLDNFRLLKRLGCGDIGT 1493 + +SDES GL +PH D W+ I+++ + G L +F+L+K+LG GDIG Sbjct: 136 SDVSDESSSSGLSNAAYKPHRDNNDKRWVAIQEVRSRVGSSLEAKDFKLIKKLGGGDIGN 195 Query: 1494 VYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEMLDHPFLPTLYAHFTTDNLS 1673 VYLAEL+ + FA+KVM+ + +RKK++RAQ E+EIL+ LDHPFLPTLY+HF T+ S Sbjct: 196 VYLAELIGTGVSFAVKVMEKAAIAARKKLVRAQTEKEILQSLDHPFLPTLYSHFETEMNS 255 Query: 1674 CLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALEYLHMLGVIYRDLKPENILV 1853 CLVME+CPGGDLH LRQ+Q G+ FPE +ARFYVAEVLLA+EYLHMLG+IYRDLKPEN+LV Sbjct: 256 CLVMEFCPGGDLHSLRQKQRGKYFPEQAARFYVAEVLLAMEYLHMLGIIYRDLKPENVLV 315 Query: 1854 RDDGHIMLSDFDXXXXXXXXXXXXXXXXXXXNHQPKKLTSPCAESYCIN-SSCL-QPSCA 2027 R+DGHIMLSDFD K +S C + C++ SSC+ QP C Sbjct: 316 REDGHIMLSDFDLSLRCAVSPTLVRFAAITLE---SKSSSYCIQPTCVDQSSCIVQPDCI 372 Query: 2028 QTSCF-----XXXXXXXXXXXXXXXXXXXXQLVVEPTEARSNSFVGTHEYLAPEIIKGDG 2192 Q CF +L+ EPT ARS SFVGTHEYLAPEIIKG+G Sbjct: 373 QPVCFTPRFLSKGKHRKKSNDMSRQIRPLPELIAEPTSARSMSFVGTHEYLAPEIIKGEG 432 Query: 2193 HGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQNLRFPDNPVVSSNAKDLIRGL 2372 HGSAVDWWTFG+FLYELL+G TPFRG N TL NVV Q LRFP++P VS A+DLIRGL Sbjct: 433 HGSAVDWWTFGIFLYELLFGITPFRGGDNRATLFNVVGQPLRFPEHPNVSFAARDLIRGL 492 Query: 2373 LVKEPENRLGTLRGAAEIKQHPFFEGLNWALIRSVAPPE 2489 LVKEP++RL RGA EIKQHPFF+ +NWALIR +PP+ Sbjct: 493 LVKEPQHRLAYRRGATEIKQHPFFQSVNWALIRCTSPPQ 531
>O48963:PHOT1_ARATH Phototropin-1 - Arabidopsis thaliana (Mouse-ear cress)| Length = 996 Score = 309 bits (791), Expect = 5e-83 Identities = 168/373 (45%), Positives = 221/373 (59%) Frame = +3 Query: 1371 RPHMVKDLCWITIRQLALQQGPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMD 1550 +PH WI I+++ P+GL +F+ +K LG GD G+V+L ELV +D LFA+K MD Sbjct: 636 KPHRKDSPPWIAIQKVLESGEPIGLKHFKPVKPLGSGDTGSVHLVELVGTDQLFAMKAMD 695 Query: 1551 IEYLISRKKMLRAQAEREILEMLDHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQ 1730 +++R K+ RA+AEREIL++LDHPFLP LYA F T CL+ +Y PGG+L +L RQ Sbjct: 696 KAVMLNRNKVHRARAEREILDLLDHPFLPALYASFQTKTHICLITDYYPGGELFMLLDRQ 755 Query: 1731 PGRSFPEPSARFYVAEVLLALEYLHMLGVIYRDLKPENILVRDDGHIMLSDFDXXXXXXX 1910 P + E + RFY A+V++ALEYLH G+IYRDLKPEN+L++ +G I LSDFD Sbjct: 756 PRKVLKEDAVRFYAAQVVVALEYLHCQGIIYRDLKPENVLIQGNGDISLSDFD------- 808 Query: 1911 XXXXXXXXXXXXNHQPKKLTSPCAESYCINSSCLQPSCAQTSCFXXXXXXXXXXXXXXXX 2090 + +P+ L E Q QT F Sbjct: 809 -------LSCLTSCKPQLLIPSIDE----KKKKKQQKSQQTPIF---------------- 841 Query: 2091 XXXXQLVVEPTEARSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRG 2270 + EP A SNSFVGT EY+APEII G GH SAVDWW G+ +YE+LYG TPFRG Sbjct: 842 ------MAEPMRA-SNSFVGTEEYIAPEIISGAGHTSAVDWWALGILMYEMLYGYTPFRG 894 Query: 2271 PGNDETLANVVSQNLRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPFFEG 2450 +T NV+ ++L+FP + S K LI LL ++P+ RLG GA E+KQH FF+G Sbjct: 895 KTRQKTFTNVLQKDLKFPASIPASLQVKQLIFRLLQRDPKKRLGCFEGANEVKQHSFFKG 954 Query: 2451 LNWALIRSVAPPE 2489 +NWALIR PPE Sbjct: 955 INWALIRCTNPPE 967
>P93025:PHOT2_ARATH Phototropin-2 - Arabidopsis thaliana (Mouse-ear cress)| Length = 915 Score = 306 bits (784), Expect = 3e-82 Identities = 163/371 (43%), Positives = 219/371 (59%) Frame = +3 Query: 1374 PHMVKDLCWITIRQLALQQGPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDI 1553 PH + W I+++ +GL +F+ +K LG GD G+V+L EL + L+A+K M+ Sbjct: 551 PHNKESTSWKAIKKIQASGETVGLHHFKPIKPLGSGDTGSVHLVELKGTGELYAMKAMEK 610 Query: 1554 EYLISRKKMLRAQAEREILEMLDHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQP 1733 +++R K RA EREI+ +LDHPFLPTLYA F T CL+ ++CPGG+L L RQP Sbjct: 611 TMMLNRNKAHRACIEREIISLLDHPFLPTLYASFQTSTHVCLITDFCPGGELFALLDRQP 670 Query: 1734 GRSFPEPSARFYVAEVLLALEYLHMLGVIYRDLKPENILVRDDGHIMLSDFDXXXXXXXX 1913 + E SARFY AEV++ LEYLH LG++YRDLKPENIL++ DGHI+L+DFD Sbjct: 671 MKILTEDSARFYAAEVVIGLEYLHCLGIVYRDLKPENILLKKDGHIVLADFDL------- 723 Query: 1914 XXXXXXXXXXXNHQPKKLTSPCAESYCINSSCLQPSCAQTSCFXXXXXXXXXXXXXXXXX 2093 + C I ++ PS + S Sbjct: 724 ----------------SFMTTCTPQLIIPAA---PSKRRRS----------------KSQ 748 Query: 2094 XXXQLVVEPTEARSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGP 2273 V EP+ +SNSFVGT EY+APEII G GH SA+DWW G+ LYE+LYGRTPFRG Sbjct: 749 PLPTFVAEPS-TQSNSFVGTEEYIAPEIITGAGHTSAIDWWALGILLYEMLYGRTPFRGK 807 Query: 2274 GNDETLANVVSQNLRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPFFEGL 2453 +T AN++ ++L FP + VS + LI LL ++P +RLG+ GA EIKQH FF G+ Sbjct: 808 NRQKTFANILHKDLTFPSSIPVSLVGRQLINTLLNRDPSSRLGSKGGANEIKQHAFFRGI 867 Query: 2454 NWALIRSVAPP 2486 NW LIR ++PP Sbjct: 868 NWPLIRGMSPP 878
>O42626:NRC2_NEUCR Serine/threonine-protein kinase nrc-2 - Neurospora crassa| Length = 623 Score = 276 bits (707), Expect = 3e-73 Identities = 172/466 (36%), Positives = 241/466 (51%), Gaps = 20/466 (4%) Frame = +3 Query: 1200 AEGEINPGPEKSDERSSEWLTLEKGERSQNSKS-----SISEYGCSTSISDESQFGLYGY 1364 A+G + G D ++ L+ E E S++S + STS++ GL G Sbjct: 151 AQGLFSKGQGNGDRPATAELSKEPLEESKDSNTVGFAEQKPNNDSSTSLAAPDADGL-GA 209 Query: 1365 NNRPHMVKDLCW---ITIRQLALQQGPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFA 1535 P L + + + ++ +G +F +K +G GD+G VYL + S L+A Sbjct: 210 LPPPIRQSPLAFRRTYSSNSIKVRNVEVGPQSFDKIKLIGKGDVGKVYLVKEKKSGRLYA 269 Query: 1536 LKVMDIEYLISRKKMLRAQAEREILEMLDHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHV 1715 +KV+ + +I R K+ RA AE+EIL +HPF+ TLY F +++ L MEYC GG+ Sbjct: 270 MKVLSKKEMIKRNKIKRALAEQEILATSNHPFIVTLYHSFQSEDYLYLCMEYCSGGEFFR 329 Query: 1716 LRQRQPGRSFPEPSARFYVAEVLLALEYLHMLGVIYRDLKPENILVRDDGHIMLSDFDXX 1895 Q +PG+ PE ARFY AEV ALEYLH++G IYRDLKPENIL+ GHIMLSDFD Sbjct: 330 ALQTRPGKCIPEDDARFYAAEVTAALEYLHLMGFIYRDLKPENILLHQSGHIMLSDFDL- 388 Query: 1896 XXXXXXXXXXXXXXXXXNHQPKKLTSPCAESYCI-----NSSCLQPSCAQTSCFXXXXXX 2060 K + P + I S+ P+ SC Sbjct: 389 ---------------------SKQSDPGGKPTMIIGKNGTSTSSLPTIDTKSCI------ 421 Query: 2061 XXXXXXXXXXXXXXQLVVEPTEARSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYE 2240 R+NSFVGT EY+APE+IKG GH SAVDWWT G+ +YE Sbjct: 422 --------------------ANFRTNSFVGTEEYIAPEVIKGSGHTSAVDWWTLGILIYE 461 Query: 2241 LLYGRTPFRGPGNDETLANVVSQNLRFPDN---PVVSSNAKDLIRGLLVKEPENRLGTLR 2411 +LYG TPF+G + T AN++ +++ FPD+ P +S+ K LIR LL+K+ RLG Sbjct: 462 MLYGTTPFKGKNRNATFANILREDIPFPDHAGAPQISNLCKSLIRKLLIKDENRRLGARA 521 Query: 2412 GAAEIKQHPFFEGLNWALIRSVAPP----ETRPCDVVTLATVRKKK 2537 GA++IK HPFF WALIR + PP + R D + V++ + Sbjct: 522 GASDIKTHPFFRTTQWALIRHMKPPIVPNQGRGIDTLNFRNVKESE 567
>Q9LSF1:OXI1_ARATH Serine/threonine-protein kinase OXI1 - Arabidopsis thaliana| (Mouse-ear cress) Length = 421 Score = 206 bits (523), Expect = 6e-52 Identities = 129/367 (35%), Positives = 186/367 (50%), Gaps = 9/367 (2%) Frame = +3 Query: 1425 QQGPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKK--------M 1580 Q L + +L LG G G V+L D+ L ALKV+ E + +KK Sbjct: 8 QSRALDFNRLEVLSLLGRGAKGVVFLVRDDDAK-LLALKVILKEAIEKKKKGRESEDDEY 66 Query: 1581 LRAQAEREILEMLDHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSA 1760 R E+ +L DHP P+L+ TD + ++YCPG +L+ LR+ Q F + Sbjct: 67 KRVSFEQGVLSRFDHPLFPSLHGVLATDKVIGYAIDYCPGQNLNSLRKMQSESMFSDEII 126 Query: 1761 RFYVAEVLLALEYLHMLGVIYRDLKPENILVRDDGHIMLSDFDXXXXXXXXXXXXXXXXX 1940 RFY AE++LAL+YLH G++YRDLKP+N++++++GH+ML DFD Sbjct: 127 RFYAAELVLALDYLHNQGIVYRDLKPDNVMIQENGHLMLIDFDLSTNLAPRTPQPSPSLS 186 Query: 1941 XXNHQPKKLTSPCA-ESYCINSSCLQPSCAQTSCFXXXXXXXXXXXXXXXXXXXXQLVVE 2117 + K+ S+C + Q S + S V + Sbjct: 187 KPSPTMKRKKRLFRFTSFCNSGISPQESISVHSSSTLA-------------------VSD 227 Query: 2118 PTEARSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLAN 2297 + +SNSFVGT EY+APE+I GDGH AVDWW+ GV LYE+LYG TPFRG ET Sbjct: 228 SSGEKSNSFVGTEEYVAPEVISGDGHDFAVDWWSLGVVLYEMLYGATPFRGSNRKETFYR 287 Query: 2298 VVSQNLRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPFFEGLNWALIRSV 2477 ++S+ P+ +++ +DLIR LL K+P R+ EIK H FF G++W + V Sbjct: 288 ILSKP---PNLTGETTSLRDLIRRLLEKDPSRRI----NVEEIKGHDFFRGVDWEKVILV 340 Query: 2478 APPETRP 2498 + P P Sbjct: 341 SRPPYIP 347
>P31034:CBK1_KLULA Serine/threonine-protein kinase CBK1 - Kluyveromyces lactis (Yeast)| (Candida sphaerica) Length = 718 Score = 190 bits (483), Expect = 2e-47 Identities = 124/360 (34%), Positives = 180/360 (50%), Gaps = 3/360 (0%) Frame = +3 Query: 1416 LALQQGPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQA 1595 L L++ L LD+F +K +G G G V L + D+ ++A+K + + ++ ++ +A Sbjct: 291 LRLRRTRLSLDDFNSVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYNKDQLAHVKA 350 Query: 1596 EREILEMLDHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVA 1775 ER++L D P++ +LY F L+ME+ PGGDL + R + F E RFY+A Sbjct: 351 ERDVLAGSDSPWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIR--WQIFTEDVTRFYMA 408 Query: 1776 EVLLALEYLHMLGVIYRDLKPENILVRDDGHIMLSDFDXXXXXXXXXXXXXXXXXXXNHQ 1955 E +LA+E +H LG I+RD+KP+NIL+ GHI LSDF + Sbjct: 409 ECILAIEVIHKLGFIHRDIKPDNILIDIRGHIKLSDFGLSTGFHKTHDSSYYKKLLQEDE 468 Query: 1956 PKKLTSPCAESYCINSSCLQ-PSCAQTSCFXXXXXXXXXXXXXXXXXXXXQLVVEPTEAR 2132 KK + +N Q P+ +T+ Q + Sbjct: 469 AKKQQQQQQQQQQLNLQKPQLPN--ETNNGNRNTMLVDAIHLTMTNRQQMQTWRKSRRLM 526 Query: 2133 SNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVS-- 2306 + S VGT +Y+APEI G+G DWW+ G +YE L G PF ET +++ Sbjct: 527 AYSTVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFE 586 Query: 2307 QNLRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPFFEGLNWALIRSVAPP 2486 Q L+FPD+ +S A+DLIR LL ENRLG GA EIK HPFF G++W IR V P Sbjct: 587 QTLQFPDDIHISYEAEDLIRRLLT-HSENRLGRHGGADEIKAHPFFSGVDWNTIRQVEAP 645
>P53894:CBK1_YEAST Serine/threonine-protein kinase CBK1 - Saccharomyces cerevisiae| (Baker's yeast) Length = 756 Score = 181 bits (458), Expect = 2e-44 Identities = 120/360 (33%), Positives = 178/360 (49%), Gaps = 3/360 (0%) Frame = +3 Query: 1416 LALQQGPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQA 1595 L L++ L L++F +K +G G G V L + D+ ++A+K + + + ++ +A Sbjct: 340 LRLRRTRLSLEDFHTVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYKKDQLAHVKA 399 Query: 1596 EREILEMLDHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVA 1775 ER++L D P++ +LY F L+ME+ PGGDL + R + F E RFY+A Sbjct: 400 ERDVLAGSDSPWVVSLYYSFQDAQYLYLIMEFLPGGDLMTMLIRW--QLFTEDVTRFYMA 457 Query: 1776 EVLLALEYLHMLGVIYRDLKPENILVRDDGHIMLSDFDXXXXXXXXXXXXXXXXXXXNHQ 1955 E +LA+E +H LG I+RD+KP+NIL+ GHI LSDF Q Sbjct: 458 ECILAIETIHKLGFIHRDIKPDNILIDIRGHIKLSDFGLSTGFHKTHDSNYYKKLL---Q 514 Query: 1956 PKKLTSPCAESYCINSSCLQ-PSCAQTSCFXXXXXXXXXXXXXXXXXXXXQLVVEPTEAR 2132 + T+ ++ N++ + QT +L+ T Sbjct: 515 QDEATNGISKPGTYNANTTDTANKRQTMVVDSISLTMSNRQQIQTWRKSRRLMAYST--- 571 Query: 2133 SNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVS-- 2306 VGT +Y+APEI G+G DWW+ G +YE L G PF ET +++ Sbjct: 572 ----VGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFE 627 Query: 2307 QNLRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPFFEGLNWALIRSVAPP 2486 Q L+FPD+ +S A+DLIR LL + RLG GA EIK HPFF G++W IR V P Sbjct: 628 QTLQFPDDIHISYEAEDLIRRLLT-HADQRLGRHGGADEIKSHPFFRGVDWNTIRQVEAP 686
>Q6BLJ9:CBK1_DEBHA Serine/threonine-protein kinase CBK1 - Debaryomyces hansenii (Yeast)| (Torulaspora hansenii) Length = 716 Score = 181 bits (458), Expect = 2e-44 Identities = 119/359 (33%), Positives = 176/359 (49%), Gaps = 2/359 (0%) Frame = +3 Query: 1416 LALQQGPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQA 1595 L L++ L L++F +K +G G G V L + D+ ++A+K + + + ++ +A Sbjct: 303 LRLRRTKLSLEDFNTVKVIGKGAFGEVRLVQKRDTGKIYAMKTLLKSEMYKKDQLAHVKA 362 Query: 1596 EREILEMLDHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVA 1775 ER++L D P++ +LY F L+ME+ PGGDL + R + F E RFY+A Sbjct: 363 ERDVLAGSDSPWVVSLYYSFQDAQYLYLIMEFLPGGDLMTMLIRW--QIFTEDITRFYMA 420 Query: 1776 EVLLALEYLHMLGVIYRDLKPENILVRDDGHIMLSDFDXXXXXXXXXXXXXXXXXXXNHQ 1955 E +LA+E +H LG I+RD+KP+NIL+ GHI LSDF Sbjct: 421 ECVLAIEAIHKLGFIHRDIKPDNILIDIRGHIKLSDFGLSTGFHKTHDSNYYKKLLEKEN 480 Query: 1956 PKKLTSPCAESYCINSSCLQPSCAQTSCFXXXXXXXXXXXXXXXXXXXXQLVVEPTEARS 2135 P T+P N + PS A + Q + + Sbjct: 481 PHH-TNP------QNGNLQAPSMATNN---RNSMMVDAIHLTMSNRQQMQTWRKSRRLMA 530 Query: 2136 NSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVS--Q 2309 S VGT +Y+APEI G+G DWW+ G ++E L G PF ET +++ + Sbjct: 531 YSTVGTPDYIAPEIFVHQGYGQECDWWSLGAIMFECLIGWPPFCSETPHETYRKILNWQE 590 Query: 2310 NLRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPFFEGLNWALIRSVAPP 2486 L+ PD+ +S ++DLIR LL ENRLG GA E+K HPFF G++W IR V P Sbjct: 591 TLQIPDDIHLSPESEDLIRKLLT-NAENRLGRYNGADELKLHPFFRGVDWDTIRKVDAP 648
>Q6FP74:CBK1_CANGA Serine/threonine-protein kinase CBK1 - Candida glabrata (Yeast)| (Torulopsis glabrata) Length = 773 Score = 179 bits (453), Expect = 7e-44 Identities = 120/359 (33%), Positives = 176/359 (49%), Gaps = 2/359 (0%) Frame = +3 Query: 1416 LALQQGPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQA 1595 L L++ L L++F ++ +G G G V L + D+ ++A+K + + + ++ +A Sbjct: 358 LRLRRTRLSLEDFHTVQVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYKKDQLAHVKA 417 Query: 1596 EREILEMLDHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVA 1775 ER++L D P++ +LY F L+ME+ PGGDL + R + F E RFY+A Sbjct: 418 ERDVLAGTDSPWIVSLYYSFQDAQYLYLIMEFLPGGDLMTMLIRW--QLFTEDVTRFYMA 475 Query: 1776 EVLLALEYLHMLGVIYRDLKPENILVRDDGHIMLSDFDXXXXXXXXXXXXXXXXXXXNHQ 1955 E +LA+E +H LG I+RD+KP+NIL+ GHI LSDF N+ Sbjct: 476 ECILAIETIHKLGFIHRDIKPDNILIDIRGHIKLSDF--------GLSTGFHKTHDSNYY 527 Query: 1956 PKKLTSPCAESYCINSSCLQPSCAQTSCFXXXXXXXXXXXXXXXXXXXXQLVVEPTEARS 2135 K L E+ N + P+ A Q + + Sbjct: 528 KKLLQQD--EATTKNGA---PNDAGDGSNNRQTMIVDSINLTMSNRQQIQTWRKSRRLMA 582 Query: 2136 NSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVS--Q 2309 S VGT +Y+APEI G+G DWW+ G +YE L G PF ET +++ Q Sbjct: 583 YSTVGTPDYIAPEIFLYQGYGQDCDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQ 642 Query: 2310 NLRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPFFEGLNWALIRSVAPP 2486 L+FP++ +S A+DLIR LL RLG GA EIK HPFF G++W IR V P Sbjct: 643 TLQFPEDVHISYEAEDLIRRLLT-HSNQRLGRQGGADEIKSHPFFRGVDWNTIRQVEAP 700
>Q9NBK5:ST38L_DROME Serine/threonine-protein kinase 38-like - Drosophila melanogaster| (Fruit fly) Length = 463 Score = 166 bits (421), Expect = 4e-40 Identities = 112/373 (30%), Positives = 179/373 (47%), Gaps = 10/373 (2%) Frame = +3 Query: 1416 LALQQGPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQA 1595 L L++ LG+++F LK +G G G V L + D+ ++A+KV+ ++ ++++ +A Sbjct: 81 LRLKRLRLGVEDFEALKVIGRGAFGEVRLVQKKDTGHVYAMKVLRKADMLEKEQVAHVRA 140 Query: 1596 EREILEMLDHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVA 1775 ER++L DH ++ +Y F L+ME+ PGGD+ L ++ + E +FY++ Sbjct: 141 ERDVLVEADHQWVVKMYYSFQDPVNLYLIMEFLPGGDMMTLLMKKD--TLSEEGTQFYIS 198 Query: 1776 EVLLALEYLHMLGVIYRDLKPENILVRDDGHIMLSDFDXXXXXXXXXXXXXXXXXXXNHQ 1955 E LA++ +H LG I+RD+KP+N+L+ GH+ LSDF Sbjct: 199 ETALAIDSIHKLGFIHRDIKPDNLLLDARGHLKLSDFGLCTG------------------ 240 Query: 1956 PKKLTSPCAESYCINSSCLQPS-----CAQTSCFXXXXXXXXXXXXXXXXXXXXQLVVEP 2120 L + + S +PS CA SC + Sbjct: 241 ---LKKSHRTDFYRDLSQAKPSDFIGTCASLSC------------SPMDSKRRAESWKRN 285 Query: 2121 TEARSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANV 2300 A + S VGT +Y+APE+ G+G A DWW+ GV +YE+L G PF +T V Sbjct: 286 RRALAYSTVGTPDYIAPEVFLQTGYGPACDWWSLGVIMYEMLMGYPPFCSDNPQDTYRKV 345 Query: 2301 VS--QNLRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPFFEGLNWALIR- 2471 ++ + L FP +S AK+ I E + RLG+ RG ++K PFF G++W IR Sbjct: 346 MNWRETLIFPPEIPISEEAKETIINFCC-EADRRLGSQRGLEDLKSVPFFRGVDWEHIRE 404 Query: 2472 --SVAPPETRPCD 2504 + P E R D Sbjct: 405 RPAAIPVEVRSID 417
>O95835:LATS1_HUMAN Serine/threonine-protein kinase LATS1 - Homo sapiens (Human)| Length = 1130 Score = 166 bits (421), Expect = 4e-40 Identities = 125/385 (32%), Positives = 182/385 (47%), Gaps = 10/385 (2%) Frame = +3 Query: 1380 MVKDLCWITIRQLALQQGPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEY 1559 M K LC + L++ + F +K LG G G V LA VD+ L+A K + + Sbjct: 681 MRKMLCQKESNYIRLKRAKMDKSMFVKIKTLGIGAFGEVCLARKVDTKALYATKTLRKKD 740 Query: 1560 LISRKKMLRAQAEREILEMLDHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGR 1739 ++ R ++ +AER+IL D+ ++ LY F + VM+Y PGGD+ L R Sbjct: 741 VLLRNQVAHVKAERDILAEADNEWVVRLYYSFQDKDNLYFVMDYIPGGDMMSLLIRMG-- 798 Query: 1740 SFPEPSARFYVAEVLLALEYLHMLGVIYRDLKPENILVRDDGHIMLSDFDXXXXXXXXXX 1919 FPE ARFY+AE+ A+E +H +G I+RD+KP+NIL+ DGHI L+DF Sbjct: 799 IFPESLARFYIAELTCAVESVHKMGFIHRDIKPDNILIDRDGHIKLTDF----------- 847 Query: 1920 XXXXXXXXXNHQPKKLTS---PCAESYCINSSCLQPSCAQTSCFXXXXXXXXXXXXXXXX 2090 H K S P +S ++ PS SC Sbjct: 848 -GLCTGFRWTHDSKYYQSGDHPRQDSMDFSNEWGDPS----SC----------RCGDRLK 892 Query: 2091 XXXXQLVVEPTEARSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRG 2270 + + ++S VGT Y+APE++ G+ DWW+ GV L+E+L G+ PF Sbjct: 893 PLERRAARQHQRCLAHSLVGTPNYIAPEVLLRTGYTQLCDWWSVGVILFEMLVGQPPFLA 952 Query: 2271 PGNDETLANVVS--QNLRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPFF 2444 ET V++ +L P +S A DLI L + PE+RLG GA EIK HPFF Sbjct: 953 QTPLETQMKVINWQTSLHIPPQAKLSPEASDLII-KLCRGPEDRLGK-NGADEIKAHPFF 1010 Query: 2445 EGLNWA-----LIRSVAPPETRPCD 2504 + ++++ S P T P D Sbjct: 1011 KTIDFSSDLRQQSASYIPKITHPTD 1035
>Q8BYR2:LATS1_MOUSE Serine/threonine-protein kinase LATS1 - Mus musculus (Mouse)| Length = 1129 Score = 163 bits (412), Expect = 4e-39 Identities = 123/385 (31%), Positives = 179/385 (46%), Gaps = 10/385 (2%) Frame = +3 Query: 1380 MVKDLCWITIRQLALQQGPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEY 1559 M K LC + L++ + F +K LG G G V LA VD+ L+A K + + Sbjct: 680 MRKMLCQKESNYIRLKRAKMDKSMFVKIKTLGIGAFGEVCLARKVDTKALYATKTLRKKD 739 Query: 1560 LISRKKMLRAQAEREILEMLDHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGR 1739 ++ R ++ +AER+IL D+ ++ LY F + VM+Y PGGD+ L R Sbjct: 740 VLLRNQVAHVKAERDILAEADNEWVVRLYYSFQDKDNLYFVMDYIPGGDMMSLLIRMG-- 797 Query: 1740 SFPEPSARFYVAEVLLALEYLHMLGVIYRDLKPENILVRDDGHIMLSDFDXXXXXXXXXX 1919 FPE ARFY+AE+ A+E +H +G I+RD+KP+NIL+ DGHI L+DF Sbjct: 798 IFPENLARFYIAELTCAVESVHKMGFIHRDIKPDNILIDRDGHIKLTDF----------- 846 Query: 1920 XXXXXXXXXNHQPKKLTS---PCAESYCINSSCLQPSCAQTSCFXXXXXXXXXXXXXXXX 2090 H K S P +S ++ PS + Sbjct: 847 -GLCTGFRWTHDSKYYQSGDHPRQDSMDFSNEWGDPSNCRCG--------------DRLK 891 Query: 2091 XXXXQLVVEPTEARSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRG 2270 + + ++S VGT Y+APE++ G+ DWW+ GV L E+L G+ PF Sbjct: 892 PLERRAARQHQRCLAHSLVGTPNYIAPEVLLRTGYTQLCDWWSVGVILCEMLVGQPPFLA 951 Query: 2271 PGNDETLANVV--SQNLRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPFF 2444 ET V+ +L P +S A DLI L + PE+RLG GA EIK HPFF Sbjct: 952 QTPLETQMKVIIWQTSLHIPPQAKLSPEASDLII-KLCRGPEDRLGK-NGADEIKAHPFF 1009 Query: 2445 EGLNWA-----LIRSVAPPETRPCD 2504 + ++++ S P T P D Sbjct: 1010 KTIDFSSDLRQQSASYIPKITHPTD 1034
>Q7TSJ6:LATS2_MOUSE Serine/threonine-protein kinase LATS2 - Mus musculus (Mouse)| Length = 1042 Score = 156 bits (394), Expect = 5e-37 Identities = 109/349 (31%), Positives = 171/349 (48%), Gaps = 2/349 (0%) Frame = +3 Query: 1422 LQQGPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAER 1601 L++ + F +K LG G G V LA +D+ L+A+K + + +++R ++ +AER Sbjct: 616 LKRAKMDKSMFVKIKTLGIGAFGEVCLACKLDTHALYAMKTLRKKDVLNRNQVAHVKAER 675 Query: 1602 EILEMLDHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEV 1781 +IL D+ ++ LY F + VM+Y PGGD+ L R FPE ARFY+AE+ Sbjct: 676 DILAEADNEWVVKLYYSFQDKDSLYFVMDYIPGGDMMSLLIRM--EVFPEHLARFYIAEL 733 Query: 1782 LLALEYLHMLGVIYRDLKPENILVRDDGHIMLSDFDXXXXXXXXXXXXXXXXXXXNHQPK 1961 LA+E +H +G I+RD+KP+NIL+ DGHI L+ D NH + Sbjct: 734 TLAIESVHKMGFIHRDIKPDNILIDLDGHIKLT--DFGLCTGFRWTHNSKYYQKGNHMRQ 791 Query: 1962 KLTSPCAESYCINSSCLQPSCAQTSCFXXXXXXXXXXXXXXXXXXXXQLVVEPTEARSNS 2141 P + + S+C +T + + ++S Sbjct: 792 DSMEP-GDLWDDVSNCRCGDRLKT--------------------LEQRAQKQHQRCLAHS 830 Query: 2142 FVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVS--QNL 2315 VGT Y+APE++ G+ DWW+ GV L+E+L G+ PF P ET V++ L Sbjct: 831 LVGTPNYIAPEVLLRKGYTQLCDWWSVGVILFEMLVGQPPFLAPTPTETQLKVINWESTL 890 Query: 2316 RFPDNPVVSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPFFEGLNWA 2462 P +S+ A+DLI L + RLG GA ++K HPFF ++++ Sbjct: 891 HIPTQVRLSAEARDLITKLCC-AADCRLGR-DGADDLKAHPFFNTIDFS 937
>Q09831:PPK14_SCHPO Serine/threonine-protein kinase ppk14 - Schizosaccharomyces pombe| (Fission yeast) Length = 566 Score = 150 bits (380), Expect = 2e-35 Identities = 77/151 (50%), Positives = 98/151 (64%) Frame = +3 Query: 1437 LGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEM 1616 +G +F + LG GD+G VYL S +A+KV+ + +I R K RA AE+ IL Sbjct: 190 VGPSSFEKVFLLGKGDVGRVYLVREKKSGKFYAMKVLSKQEMIKRNKSKRAFAEQHILAT 249 Query: 1617 LDHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALE 1796 +HPF+ TLY F +D L MEYC GG+ QR+PGR E A+FY+AEV ALE Sbjct: 250 SNHPFIVTLYHSFQSDEYLYLCMEYCMGGEFFRALQRRPGRCLSENEAKFYIAEVTAALE 309 Query: 1797 YLHMLGVIYRDLKPENILVRDDGHIMLSDFD 1889 YLH++G IYRDLKPENIL+ + GHIMLSDFD Sbjct: 310 YLHLMGFIYRDLKPENILLHESGHIMLSDFD 340 Score = 149 bits (375), Expect = 8e-35 Identities = 73/148 (49%), Positives = 98/148 (66%), Gaps = 6/148 (4%) Frame = +3 Query: 2130 RSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQ 2309 R+NSFVGT EY+APE+IKG GH SAVDWWT G+ YE+LY TPF+G + T +N++ + Sbjct: 378 RTNSFVGTEEYIAPEVIKGCGHTSAVDWWTLGILFYEMLYATTPFKGKNRNMTFSNILHK 437 Query: 2310 NLRFP---DNPVVSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPFFEGLNWALIRSVA 2480 ++ FP D P +SS K+LIR LLVK+ +RLG+ GAA++K HPFF+ + WAL+R Sbjct: 438 DVIFPEYADAPSISSLCKNLIRKLLVKDENDRLGSQAGAADVKLHPFFKNVQWALLRHTE 497 Query: 2481 P---PETRPCDVVTLATVRKKKEGKCLD 2555 P P+ P D + KE K LD Sbjct: 498 PPIIPKLAPIDEKGNPNISHLKESKSLD 525
>P25341:KIN82_YEAST Probable serine/threonine-protein kinase KIN82 - Saccharomyces| cerevisiae (Baker's yeast) Length = 720 Score = 149 bits (375), Expect = 8e-35 Identities = 63/119 (52%), Positives = 93/119 (78%) Frame = +3 Query: 2130 RSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQ 2309 R+NSFVGT EYLAPE+I+G+GH +AVDWWT G+ +YE+L+G TPF+G ++ET +N++++ Sbjct: 498 RTNSFVGTEEYLAPEVIRGNGHTAAVDWWTLGILIYEMLFGCTPFKGDNSNETFSNILTK 557 Query: 2310 NLRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPFFEGLNWALIRSVAPP 2486 +++FP + VS N KDLI+ LL K RLG+ GAA+IK+HPFF+ + W+ +R+ PP Sbjct: 558 DVKFPHDKEVSKNCKDLIKKLLNKNEAKRLGSKSGAADIKRHPFFKKVQWSFLRNQDPP 616 Score = 148 bits (373), Expect = 1e-34 Identities = 74/147 (50%), Positives = 97/147 (65%) Frame = +3 Query: 1449 NFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEMLDHP 1628 +F ++ LG GD+G VYL D++ +FALKV++ +I RKK+ R E+EIL DHP Sbjct: 323 SFEKIRLLGQGDVGKVYLMRERDTNQIFALKVLNKHEMIKRKKIKRVLTEQEILATSDHP 382 Query: 1629 FLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALEYLHM 1808 F+ TLY F T + L MEYC GG+ Q + + E A+FY +EV+ ALEYLH+ Sbjct: 383 FIVTLYHSFQTKDYLYLCMEYCMGGEFFRALQTRKSKCIAEEDAKFYASEVVAALEYLHL 442 Query: 1809 LGVIYRDLKPENILVRDDGHIMLSDFD 1889 LG IYRDLKPENIL+ GH+MLSDFD Sbjct: 443 LGFIYRDLKPENILLHQSGHVMLSDFD 469
>P53739:KN8R_YEAST Probable serine/threonine-protein kinase YNR047W - Saccharomyces| cerevisiae (Baker's yeast) Length = 893 Score = 146 bits (369), Expect = 4e-34 Identities = 61/119 (51%), Positives = 87/119 (73%) Frame = +3 Query: 2130 RSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQ 2309 R+NSFVGT EY+APE+I+G+GH +AVDWWT G+ +YE+L+G TPF+G +ET N++ Sbjct: 673 RTNSFVGTEEYIAPEVIRGNGHTAAVDWWTLGILIYEMLFGFTPFKGDNTNETFTNILKN 732 Query: 2310 NLRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPFFEGLNWALIRSVAPP 2486 + FP+N +S KDLI+ LL K RLG GAA++K+HPFF+ + W+L+R+ PP Sbjct: 733 EVSFPNNNEISRTCKDLIKKLLTKNESKRLGCKMGAADVKKHPFFKKVQWSLLRNQEPP 791 Score = 140 bits (352), Expect = 4e-32 Identities = 71/151 (47%), Positives = 97/151 (64%) Frame = +3 Query: 1437 LGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEM 1616 +G +F ++ LG GD+G V+L ++ ++ALKV+ + +I R K+ R E+EIL Sbjct: 491 VGPQSFEKIRLLGQGDVGKVFLVREKKTNRVYALKVLSKDEMIKRNKIKRVLTEQEILAT 550 Query: 1617 LDHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALE 1796 +HPF+ TLY F +++ L MEYC GG+ Q + + E ARFY +EV ALE Sbjct: 551 SNHPFIVTLYHSFQSEDYLYLCMEYCMGGEFFRALQTRKTKCICEDDARFYASEVTAALE 610 Query: 1797 YLHMLGVIYRDLKPENILVRDDGHIMLSDFD 1889 YLH+LG IYRDLKPENIL+ GHIMLSDFD Sbjct: 611 YLHLLGFIYRDLKPENILLHQSGHIMLSDFD 641
>Q9USX7:PPK22_SCHPO Serine/threonine-protein kinase ppk22 - Schizosaccharomyces pombe| (Fission yeast) Length = 526 Score = 145 bits (367), Expect = 7e-34 Identities = 66/122 (54%), Positives = 88/122 (72%), Gaps = 3/122 (2%) Frame = +3 Query: 2130 RSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQ 2309 R+NSFVGT EY+APE+I+ GH AVDWWT G+F+YE+LYG TPF+G T +N++ Sbjct: 338 RTNSFVGTEEYIAPEVIRSCGHTVAVDWWTLGIFIYEILYGTTPFKGKNRHATFSNILYS 397 Query: 2310 NLRFPD---NPVVSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPFFEGLNWALIRSVA 2480 ++ FP+ P VSS K LIR LLVK+ R G++ GA++IKQHPFF + WAL+RS+ Sbjct: 398 DVSFPEYHGAPNVSSTCKSLIRRLLVKDESKRCGSVAGASDIKQHPFFRHIQWALLRSMK 457 Query: 2481 PP 2486 PP Sbjct: 458 PP 459 Score = 139 bits (351), Expect = 5e-32 Identities = 72/147 (48%), Positives = 91/147 (61%) Frame = +3 Query: 1449 NFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEMLDHP 1628 +F ++ LG GD+G VYL + LFA+K+++ +I R K+ R AE+EIL HP Sbjct: 154 SFEKIRLLGQGDVGKVYLVRQKSNHRLFAMKILNKREMIKRHKVNRVLAEQEILTKSKHP 213 Query: 1629 FLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALEYLHM 1808 F+ TLY F + + L MEYC GG+ P PE A FY AEV ALEYLH+ Sbjct: 214 FIVTLYHSFQSRDYLYLCMEYCAGGEFFRALHSLPKHILPEKDACFYAAEVTAALEYLHL 273 Query: 1809 LGVIYRDLKPENILVRDDGHIMLSDFD 1889 +G IYRDLKPENIL+ GHIMLSDFD Sbjct: 274 MGFIYRDLKPENILLHQSGHIMLSDFD 300
>Q9W0V1:PDPK1_DROME 3-phosphoinositide-dependent protein kinase 1 - Drosophila| melanogaster (Fruit fly) Length = 836 Score = 129 bits (323), Expect = 9e-29 Identities = 99/363 (27%), Positives = 154/363 (42%), Gaps = 12/363 (3%) Frame = +3 Query: 1446 DNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREIL-EMLD 1622 ++F + +G G VYLA + S +A+KV + ++ +K + ERE++ +M + Sbjct: 244 NDFIFGRYIGEGSYSIVYLAVDIHSRREYAIKVCEKRLILRERKQDYIKREREVMHQMTN 303 Query: 1623 HPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALEYL 1802 P L F VM Y GD+ R SF R Y AE+LLA E++ Sbjct: 304 VPGFVNLSCTFQDQRSLYFVMTYARKGDMLPYINRVG--SFDVACTRHYAAELLLACEHM 361 Query: 1803 HMLGVIYRDLKPENILVRDDGHIMLSDFDXXXXXXXXXXXXXXXXXXXNHQPKKLTSPCA 1982 H V++RDLKPENIL+ +D H +++DF H+ T C+ Sbjct: 362 HRRNVVHRDLKPENILLDEDMHTLIADFGSAKVMTA-------------HERALATEHCS 408 Query: 1983 ESYCINSSCLQPSCAQTSCFXXXXXXXXXXXXXXXXXXXXQLVVEPTEARSN-------- 2138 E NS + Q ++ R Sbjct: 409 EQRRSNSDEDDEDSDRLENEDEDFYDRDSEELDDGDDEQQQEEMDSPRHRQRRYNRHRKA 468 Query: 2139 SFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQNLR 2318 SFVGT +Y++PE+++ A D W G +Y+++ G PFRG + ++ + Sbjct: 469 SFVGTAQYVSPEVLQNGPITPAADLWALGCIVYQMIAGLPPFRGSNDYVIFKEILDCAVD 528 Query: 2319 FPDNPVVSSNAKDLIRGLLVKEPENRLGT---LRGAAEIKQHPFFEGLNWALIRSVAPPE 2489 FP +A+DL+R LL +P +RLG I+ HPFF G++W +R PP Sbjct: 529 FPQG--FDKDAEDLVRKLLRVDPRDRLGAQDEFGYYESIRAHPFFAGIDWQTLRQQTPPP 586 Query: 2490 TRP 2498 P Sbjct: 587 IYP 589
>P06244:KAPA_YEAST cAMP-dependent protein kinase type 1 - Saccharomyces cerevisiae| (Baker's yeast) Length = 397 Score = 123 bits (309), Expect = 4e-27 Identities = 81/236 (34%), Positives = 122/236 (51%), Gaps = 10/236 (4%) Frame = +3 Query: 1209 EINPGPEKS-DERSSEWLTLEKGERSQ---------NSKSSISEYGCSTSISDESQFGLY 1358 E N G +KS D+R E +KGE S+ N S+ + G T + Y Sbjct: 5 EQNGGGQKSLDDRQGE--ESQKGETSERETTATESGNESKSVEKEGGETQEKPKQPHVTY 62 Query: 1359 GYNNRPHMVKDLCWITIRQLALQQGPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFAL 1538 YN + I Q + G L +F++L+ LG G G V+L + +A+ Sbjct: 63 -YNEEQYKQ------FIAQARVTSGKYSLQDFQILRTLGTGSFGRVHLIRSRHNGRYYAM 115 Query: 1539 KVMDIEYLISRKKMLRAQAEREILEMLDHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVL 1718 KV+ E ++ K++ ER +L ++ HPF+ ++ F ++M+Y GG+L L Sbjct: 116 KVLKKEIVVRLKQVEHTNDERLMLSIVTHPFIIRMWGTFQDAQQIFMIMDYIEGGELFSL 175 Query: 1719 RQRQPGRSFPEPSARFYVAEVLLALEYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 ++ + FP P A+FY AEV LALEYLH +IYRDLKPENIL+ +GHI ++DF Sbjct: 176 LRKS--QRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDF 229 Score = 90.1 bits (222), Expect = 4e-17 Identities = 42/120 (35%), Positives = 71/120 (59%), Gaps = 3/120 (2%) Frame = +3 Query: 2148 GTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQNLRFPD 2327 GT +Y+APE++ + ++DWW+FG+ +YE+L G TPF +T +++ LRFP Sbjct: 244 GTPDYIAPEVVSTKPYNKSIDWWSFGILIYEMLAGYTPFYDSNTMKTYEKILNAELRFP- 302 Query: 2328 NPVVSSNAKDLIRGLLVKEPENRLGTLR-GAAEIKQHPFFEGLNW--ALIRSVAPPETRP 2498 P + + KDL+ L+ ++ RLG L+ G ++K HP+F+ + W L R++ P P Sbjct: 303 -PFFNEDVKDLLSRLITRDLSQRLGNLQNGTEDVKNHPWFKEVVWEKLLSRNIETPYEPP 361
>P06245:KAPB_YEAST cAMP-dependent protein kinase type 2 - Saccharomyces cerevisiae| (Baker's yeast) Length = 380 Score = 122 bits (307), Expect = 6e-27 Identities = 61/155 (39%), Positives = 98/155 (63%) Frame = +3 Query: 1422 LQQGPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAER 1601 + +G L +F++++ LG G G V+L V + +A+KV+ + ++ K++ ER Sbjct: 60 VSKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKQQVVKMKQVEHTNDER 119 Query: 1602 EILEMLDHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEV 1781 +L++++HPFL ++ F +VM+Y GG+L L ++ + FP P A+FY AEV Sbjct: 120 RMLKLVEHPFLIRMWGTFQDARNIFMVMDYIEGGELFSLLRKS--QRFPNPVAKFYAAEV 177 Query: 1782 LLALEYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 +LALEYLH +IYRDLKPENIL+ +GHI ++DF Sbjct: 178 ILALEYLHAHNIIYRDLKPENILLDRNGHIKITDF 212 Score = 73.6 bits (179), Expect = 4e-12 Identities = 39/120 (32%), Positives = 64/120 (53%), Gaps = 3/120 (2%) Frame = +3 Query: 2148 GTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQNLRFPD 2327 GT +Y+APE+I + +VDWW+ GV +YE+L G TPF +T ++ + +P Sbjct: 227 GTPDYIAPEVITTKPYNKSVDWWSLGVLIYEMLAGYTPFYDTTPMKTYEKILQGKVVYP- 285 Query: 2328 NPVVSSNAKDLIRGLLVKEPENRLGTLR-GAAEIKQHPFFEGLNW--ALIRSVAPPETRP 2498 P + DL+ L+ + R+G L+ G+ +IK HP+F + W L + + P P Sbjct: 286 -PYFHPDVVDLLSKLITADLTRRIGNLQSGSRDIKAHPWFSEVVWERLLAKDIETPYEPP 344
>P10830:KPCE_RABIT Protein kinase C epsilon type - Oryctolagus cuniculus (Rabbit)| Length = 736 Score = 117 bits (293), Expect = 3e-25 Identities = 69/151 (45%), Positives = 89/151 (58%), Gaps = 1/151 (0%) Frame = +3 Query: 1437 LGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEM 1616 LGLD F +K LG G G V LAEL D ++A+KV+ + ++ + E+ IL + Sbjct: 402 LGLDEFNFIKVLGKGSFGKVMLAELKGKDEVYAVKVLKKDVILQDDDVDCTMTEKRILAL 461 Query: 1617 L-DHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLAL 1793 HP+L LY F T + VMEY GGDL + Q Q R F EP +RFY AEV AL Sbjct: 462 ARKHPYLTQLYCCFQTKDRLFFVMEYVNGGDL--MFQIQRSRKFDEPRSRFYAAEVTSAL 519 Query: 1794 EYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 +LH GVIYRDLK +NIL+ +GH L+DF Sbjct: 520 MFLHQHGVIYRDLKLDNILLDAEGHCKLADF 550 Score = 90.5 bits (223), Expect = 3e-17 Identities = 41/123 (33%), Positives = 72/123 (58%), Gaps = 5/123 (4%) Frame = +3 Query: 2133 SNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQN 2312 + +F GT +Y+APEI++ +G +VDWW GV +YE++ G+ PF D+ +++ + Sbjct: 563 TTTFCGTPDYIAPEILQELEYGPSVDWWALGVLMYEMMAGQPPFEADNEDDLFESILHDD 622 Query: 2313 LRFPDNPVVSSNAKDLIRGLLVKEPENRLGTL---RGAAEIKQHPFFEGLNWALI--RSV 2477 + +P +S A +++ + K P RLG + G IKQHPFF+ ++W L+ + + Sbjct: 623 VLYP--VWLSKEAVSILKAFMTKNPHKRLGCVAAQNGEDAIKQHPFFKEIDWVLLEQKKI 680 Query: 2478 APP 2486 PP Sbjct: 681 KPP 683
>P16054:KPCE_MOUSE Protein kinase C epsilon type - Mus musculus (Mouse)| Length = 737 Score = 117 bits (293), Expect = 3e-25 Identities = 69/151 (45%), Positives = 89/151 (58%), Gaps = 1/151 (0%) Frame = +3 Query: 1437 LGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEM 1616 LGLD F +K LG G G V LAEL D ++A+KV+ + ++ + E+ IL + Sbjct: 403 LGLDEFNFIKVLGKGSFGKVMLAELKGKDEVYAVKVLKKDVILQDDDVDCTMTEKRILAL 462 Query: 1617 L-DHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLAL 1793 HP+L LY F T + VMEY GGDL + Q Q R F EP +RFY AEV AL Sbjct: 463 ARKHPYLTQLYCCFQTKDRLFFVMEYVNGGDL--MFQIQRSRKFDEPRSRFYAAEVTSAL 520 Query: 1794 EYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 +LH GVIYRDLK +NIL+ +GH L+DF Sbjct: 521 MFLHQHGVIYRDLKLDNILLDAEGHCKLADF 551 Score = 90.5 bits (223), Expect = 3e-17 Identities = 41/123 (33%), Positives = 72/123 (58%), Gaps = 5/123 (4%) Frame = +3 Query: 2133 SNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQN 2312 + +F GT +Y+APEI++ +G +VDWW GV +YE++ G+ PF D+ +++ + Sbjct: 564 TTTFCGTPDYIAPEILQELEYGPSVDWWALGVLMYEMMAGQPPFEADNEDDLFESILHDD 623 Query: 2313 LRFPDNPVVSSNAKDLIRGLLVKEPENRLGTL---RGAAEIKQHPFFEGLNWALI--RSV 2477 + +P +S A +++ + K P RLG + G IKQHPFF+ ++W L+ + + Sbjct: 624 VLYP--VWLSKEAVSILKAFMTKNPHKRLGCVAAQNGEDAIKQHPFFKEIDWVLLEQKKI 681 Query: 2478 APP 2486 PP Sbjct: 682 KPP 684
>Q02156:KPCE_HUMAN Protein kinase C epsilon type - Homo sapiens (Human)| Length = 737 Score = 117 bits (293), Expect = 3e-25 Identities = 69/151 (45%), Positives = 89/151 (58%), Gaps = 1/151 (0%) Frame = +3 Query: 1437 LGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEM 1616 LGLD F +K LG G G V LAEL D ++A+KV+ + ++ + E+ IL + Sbjct: 403 LGLDEFNFIKVLGKGSFGKVMLAELKGKDEVYAVKVLKKDVILQDDDVDCTMTEKRILAL 462 Query: 1617 L-DHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLAL 1793 HP+L LY F T + VMEY GGDL + Q Q R F EP +RFY AEV AL Sbjct: 463 ARKHPYLTQLYCCFQTKDRLFFVMEYVNGGDL--MFQIQRSRKFDEPRSRFYAAEVTSAL 520 Query: 1794 EYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 +LH GVIYRDLK +NIL+ +GH L+DF Sbjct: 521 MFLHQHGVIYRDLKLDNILLDAEGHCKLADF 551 Score = 90.5 bits (223), Expect = 3e-17 Identities = 41/123 (33%), Positives = 72/123 (58%), Gaps = 5/123 (4%) Frame = +3 Query: 2133 SNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQN 2312 + +F GT +Y+APEI++ +G +VDWW GV +YE++ G+ PF D+ +++ + Sbjct: 564 TTTFCGTPDYIAPEILQELEYGPSVDWWALGVLMYEMMAGQPPFEADNEDDLFESILHDD 623 Query: 2313 LRFPDNPVVSSNAKDLIRGLLVKEPENRLGTL---RGAAEIKQHPFFEGLNWALI--RSV 2477 + +P +S A +++ + K P RLG + G IKQHPFF+ ++W L+ + + Sbjct: 624 VLYP--VWLSKEAVSILKAFMTKNPHKRLGCVASQNGEDAIKQHPFFKEIDWVLLEQKKI 681 Query: 2478 APP 2486 PP Sbjct: 682 KPP 684
>P24583:KPC1_YEAST Protein kinase C-like 1 - Saccharomyces cerevisiae (Baker's yeast)| Length = 1151 Score = 117 bits (293), Expect = 3e-25 Identities = 71/164 (43%), Positives = 100/164 (60%), Gaps = 5/164 (3%) Frame = +3 Query: 1410 RQLALQQGPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRA 1589 ++ A ++ + LDNF LLK LG G+ G V L++ ++D L A+KV+ + +I + A Sbjct: 810 KKRAAKRRKVSLDNFVLLKVLGKGNFGKVILSKSKNTDRLCAIKVLKKDNIIQNHDIESA 869 Query: 1590 QAEREILEMLD---HPFLPTLYAHFTTDNLSCLVMEYCPGGDL--HVLRQRQPGRSFPEP 1754 +AE+++ + HPFL LY F T+N ME+ GGDL HV QR R Sbjct: 870 RAEKKVFLLATKTKHPFLTNLYCSFQTENRIYFAMEFIGGGDLMWHVQNQRLSVRR---- 925 Query: 1755 SARFYVAEVLLALEYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 A+FY AEVLLAL+Y H GVIYRDLK ENIL+ +GHI ++D+ Sbjct: 926 -AKFYAAEVLLALKYFHDNGVIYRDLKLENILLTPEGHIKIADY 968 Score = 89.7 bits (221), Expect = 6e-17 Identities = 47/122 (38%), Positives = 72/122 (59%), Gaps = 3/122 (2%) Frame = +3 Query: 2130 RSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQ 2309 R+++F GT E++APEI+K + AVDWW FGV LY++L ++PF G DE +++ Sbjct: 980 RTSTFCGTPEFMAPEILKEQEYTKAVDWWAFGVLLYQMLLCQSPFSGDDEDEVFNAILTD 1039 Query: 2310 NLRFPDNPVVSSNAKDLIRGLLVKEPENRLGT-LRGAAEIKQHPFFEGLNW--ALIRSVA 2480 +P + ++ + +GLL K+PE RLG R A E+ + PFF +N+ L V Sbjct: 1040 EPLYPID--MAGEIVQIFQGLLTKDPEKRLGAGPRDADEVMEEPFFRNINFDDILNLRVK 1097 Query: 2481 PP 2486 PP Sbjct: 1098 PP 1099
>P05986:KAPC_YEAST cAMP-dependent protein kinase type 3 - Saccharomyces cerevisiae| (Baker's yeast) Length = 398 Score = 117 bits (293), Expect = 3e-25 Identities = 60/152 (39%), Positives = 90/152 (59%) Frame = +3 Query: 1431 GPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREIL 1610 G L +F++L+ LG G G V+L + +ALK + ++ K++ ER +L Sbjct: 81 GKYSLSDFQILRTLGTGSFGRVHLIRSNHNGRFYALKTLKKHTIVKLKQVEHTNDERRML 140 Query: 1611 EMLDHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLA 1790 ++ HPF+ ++ F +VM+Y GG+L L ++ + FP P A+FY AEV LA Sbjct: 141 SIVSHPFIIRMWGTFQDSQQVFMVMDYIEGGELFSLLRKS--QRFPNPVAKFYAAEVCLA 198 Query: 1791 LEYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 LEYLH +IYRDLKPENIL+ +GHI ++DF Sbjct: 199 LEYLHSKDIIYRDLKPENILLDKNGHIKITDF 230 Score = 91.7 bits (226), Expect = 2e-17 Identities = 44/120 (36%), Positives = 72/120 (60%), Gaps = 3/120 (2%) Frame = +3 Query: 2148 GTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQNLRFPD 2327 GT +Y+APE++ + +VDWW+FGV +YE+L G TPF +T N+++ L+FP Sbjct: 245 GTPDYIAPEVVSTKPYNKSVDWWSFGVLIYEMLAGYTPFYNSNTMKTYENILNAELKFP- 303 Query: 2328 NPVVSSNAKDLIRGLLVKEPENRLGTLR-GAAEIKQHPFFEGLNW--ALIRSVAPPETRP 2498 P +A+DL++ L+ ++ RLG L+ G+ ++K HP+F + W L R + P P Sbjct: 304 -PFFHPDAQDLLKKLITRDLSERLGNLQNGSEDVKNHPWFNEVIWEKLLARYIETPYEPP 362
>Q9P7J8:GAD8_SCHPO Serine/threonine-protein kinase gad8 - Schizosaccharomyces pombe| (Fission yeast) Length = 569 Score = 117 bits (293), Expect = 3e-25 Identities = 57/121 (47%), Positives = 77/121 (63%), Gaps = 2/121 (1%) Frame = +3 Query: 2130 RSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQ 2309 R+N+F GT EYLAPE++ G G+ VDWWT GV LYE++ G PF +E ++ Sbjct: 384 RTNTFCGTPEYLAPELLLGHGYTKVVDWWTLGVLLYEMITGLPPFYDENINEMYRKILQD 443 Query: 2310 NLRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPFFEGLNWALI--RSVAP 2483 LRFPDN + AKDL+ GLL + PE RLG+ GA EIK HPFF+ ++W + + + P Sbjct: 444 PLRFPDN--IDEKAKDLLSGLLTRAPEKRLGS-GGAQEIKNHPFFDDIDWKKLCAKKIQP 500 Query: 2484 P 2486 P Sbjct: 501 P 501 Score = 108 bits (271), Expect = 9e-23 Identities = 64/154 (41%), Positives = 89/154 (57%) Frame = +3 Query: 1425 QQGPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAERE 1604 Q PL +D F LLK +G G G V D+ ++ALK M +++SR ++ AER Sbjct: 221 QSTPLTIDAFELLKVVGKGSFGKVMQVRKRDTSRIYALKTMKKAHIVSRSEVDHTLAERT 280 Query: 1605 ILEMLDHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVL 1784 +L +++PF+ L F + LV+ + GG+L QR+ F A+FY+AE+L Sbjct: 281 VLAQVNNPFIVPLKFSFQSPGKLYLVLAFVNGGELFHHLQREG--CFDTYRAKFYIAELL 338 Query: 1785 LALEYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 +ALE LH VIYRDLKPENIL+ GHI L DF Sbjct: 339 VALECLHEFNVIYRDLKPENILLDYTGHIALCDF 372
>P54644:KRAC_DICDI RAC-family serine/threonine-protein kinase homolog - Dictyostelium| discoideum (Slime mold) Length = 444 Score = 117 bits (292), Expect = 3e-25 Identities = 64/174 (36%), Positives = 103/174 (59%), Gaps = 11/174 (6%) Frame = +3 Query: 1398 WITI----RQLALQQGP-------LGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKV 1544 WI I R+L L G +G+ +F LL +G G G V D+ ++A+KV Sbjct: 91 WIEILINERELLLNGGKQPKKSEKVGVADFELLNLVGKGSFGKVIQVRKKDTGEVYAMKV 150 Query: 1545 MDIEYLISRKKMLRAQAEREILEMLDHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQ 1724 + ++++ ++ +ER IL+ ++HPFL L F T++ +++Y GG+L Q Sbjct: 151 LSKKHIVEHNEVEHTLSERNILQKINHPFLVNLNYSFQTEDKLYFILDYVNGGELFYHLQ 210 Query: 1725 RQPGRSFPEPSARFYVAEVLLALEYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 + + F E R+Y AE++LALE+LH+ GVIYRDLKPEN+L+ ++GHI ++DF Sbjct: 211 KD--KKFTEDRVRYYGAEIVLALEHLHLSGVIYRDLKPENLLLTNEGHICMTDF 262 Score = 97.8 bits (242), Expect = 2e-19 Identities = 49/128 (38%), Positives = 78/128 (60%), Gaps = 2/128 (1%) Frame = +3 Query: 2109 VVEPTEARSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDET 2288 ++ PT+ ++ +F GT EYLAPE+++G+G+G VDWW+FG LYE+L G PF E Sbjct: 269 LLTPTD-KTGTFCGTPEYLAPEVLQGNGYGKQVDWWSFGSLLYEMLTGLPPFYNQDVQEM 327 Query: 2289 LANVVSQNLRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPFFEGLNWALI 2468 ++ + L FP +S +A+ L+ LL ++PE RL IK+HPFF ++W + Sbjct: 328 YRKIMMEKLSFPH--FISPDARSLLEQLLERDPEKRLA---DPNLIKRHPFFRSIDWEQL 382 Query: 2469 --RSVAPP 2486 +++ PP Sbjct: 383 FQKNIPPP 390
>P34099:KAPC_DICDI cAMP-dependent protein kinase catalytic subunit - Dictyostelium| discoideum (Slime mold) Length = 648 Score = 116 bits (290), Expect = 6e-25 Identities = 55/148 (37%), Positives = 87/148 (58%) Frame = +3 Query: 1443 LDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEMLD 1622 L F+ ++ LG G G VYL + C +A+K ++ Y++ K++ +E+ IL + Sbjct: 333 LKEFKQIRVLGTGTFGKVYLIQNTKDGCYYAMKCLNKAYVVQLKQVEHLNSEKSILSSIH 392 Query: 1623 HPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALEYL 1802 HPF+ LY F + L+ EY GG+ V + F +A+FY AE++LALE+L Sbjct: 393 HPFIVNLYQAFQDEKKLYLLFEYVAGGE--VFTHLRKSMKFSNSTAKFYAAEIVLALEFL 450 Query: 1803 HMLGVIYRDLKPENILVRDDGHIMLSDF 1886 H ++YRDLKPEN+L+ + GHI ++DF Sbjct: 451 HKQNIVYRDLKPENLLIDNQGHIKITDF 478 Score = 90.9 bits (224), Expect = 3e-17 Identities = 49/116 (42%), Positives = 70/116 (60%), Gaps = 4/116 (3%) Frame = +3 Query: 2124 EARSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLA--- 2294 E R+ + GT EYLAPEII+ GHG AVDWW G+ ++E+L G PF +D+T A Sbjct: 485 EDRTFTLCGTPEYLAPEIIQSKGHGKAVDWWALGILIFEMLAGYPPFY---DDDTFAIYN 541 Query: 2295 NVVSQNLRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLR-GAAEIKQHPFFEGLNW 2459 +++ + FP +AKDLI+ LL + RLG L+ GA ++K H +F +NW Sbjct: 542 KILAGRITFPLG--FDVDAKDLIKRLLTADRTRRLGALKDGALDVKNHRWFSDINW 595
>P12370:KAPC_DROME cAMP-dependent protein kinase catalytic subunit - Drosophila| melanogaster (Fruit fly) Length = 353 Score = 115 bits (289), Expect = 8e-25 Identities = 58/148 (39%), Positives = 94/148 (63%) Frame = +3 Query: 1443 LDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEMLD 1622 LD+F +K LG G G V + + + +A+K++D + ++ K++ E+ IL+ + Sbjct: 43 LDDFERIKTLGTGSFGRVMIVQHKPTKDYYAMKILDKQKVVKLKQVEHTLNEKRILQAIQ 102 Query: 1623 HPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALEYL 1802 PFL +L HF ++ +V+EY PGG++ R+ GR F EP +RFY A+++LA EYL Sbjct: 103 FPFLVSLRYHFKDNSNLYMVLEYVPGGEMFS-HLRKVGR-FSEPHSRFYAAQIVLAFEYL 160 Query: 1803 HMLGVIYRDLKPENILVRDDGHIMLSDF 1886 H L +IYRDLKPEN+L+ G++ ++DF Sbjct: 161 HYLDLIYRDLKPENLLIDSQGYLKVTDF 188 Score = 81.3 bits (199), Expect = 2e-14 Identities = 45/116 (38%), Positives = 62/116 (53%), Gaps = 1/116 (0%) Frame = +3 Query: 2124 EARSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVV 2303 + R+ + GT EYLAPEII G+ AVDWW GV +YE+ G PF + +V Sbjct: 195 KGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLVYEMAAGYPPFFADQPIQIYEKIV 254 Query: 2304 SQNLRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLR-GAAEIKQHPFFEGLNWALI 2468 S +RFP + S+ KDL+R LL + R G L+ G +IK +F +W I Sbjct: 255 SGKVRFPSH--FGSDLKDLLRNLLQVDLTKRYGNLKAGVNDIKNQKWFASTDWIAI 308
>Q10364:SCK2_SCHPO Serine/threonine-protein kinase sck2 - Schizosaccharomyces pombe| (Fission yeast) Length = 646 Score = 115 bits (287), Expect = 1e-24 Identities = 67/158 (42%), Positives = 92/158 (58%), Gaps = 3/158 (1%) Frame = +3 Query: 1422 LQQGPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAER 1601 L Q G D+F LK +G G G VYL D++ ++A+KV+ + ++ RK++ ER Sbjct: 256 LSQHSYGPDDFVPLKLIGKGTFGQVYLVRKKDTERVYAMKVLSKKVIVRRKEVAHTVGER 315 Query: 1602 EIL---EMLDHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYV 1772 +IL D PF+ L F T LV +Y GG+L Q+ FPE A+FY+ Sbjct: 316 DILVQTSAADSPFIVALRFSFQTPKDLYLVTDYMAGGELFWHLQKSV--RFPEERAKFYI 373 Query: 1773 AEVLLALEYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 AE+LLAL+ LH G++YRDLKPENIL+ GHI L DF Sbjct: 374 AELLLALQALHKRGIVYRDLKPENILLDVQGHIALCDF 411 Score = 92.4 bits (228), Expect = 9e-18 Identities = 46/121 (38%), Positives = 75/121 (61%), Gaps = 3/121 (2%) Frame = +3 Query: 2133 SNSFVGTHEYLAPEIIKGD-GHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQ 2309 + +F GT +YLAPE+I + G+ VD+W+ GV LYE+ G +PF + N+V Sbjct: 424 TRTFCGTTDYLAPEVILDEAGYDMMVDFWSLGVLLYEMTCGWSPFYADNTQQLYKNIVFG 483 Query: 2310 NLRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPFFEGLNWALI--RSVAP 2483 +RFP ++S A+DLI+ LL + P++RLG E+ +HPFF+G++W + + ++P Sbjct: 484 KVRFPRG-LLSVEARDLIKLLLNRNPKHRLGAHGDVEEVMKHPFFDGIDWKKLAAKEISP 542 Query: 2484 P 2486 P Sbjct: 543 P 543
>Q9NRM7:LATS2_HUMAN Serine/threonine-protein kinase LATS2 - Homo sapiens (Human)| Length = 1088 Score = 115 bits (287), Expect = 1e-24 Identities = 63/155 (40%), Positives = 96/155 (61%) Frame = +3 Query: 1422 LQQGPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAER 1601 L++ + F +K LG G G V LA VD+ L+A+K + + +++R +++ +AER Sbjct: 658 LKRAKMDKSMFVKIKTLGIGAFGEVCLACKVDTHALYAMKTLRKKDVLNRNQVVHVKAER 717 Query: 1602 EILEMLDHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEV 1781 +IL D+ ++ LY F + VM+Y PGGD+ L R FPE ARFY+AE+ Sbjct: 718 DILAEADNEWVVKLYYSFQDKDSLYFVMDYIPGGDMMSLLIRM--EVFPEHLARFYIAEL 775 Query: 1782 LLALEYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 LA+E +H +G I+RD+KP+NIL+ DGHI L+DF Sbjct: 776 TLAIESVHKMGFIHRDIKPDNILIDLDGHIKLTDF 810 Score = 78.6 bits (192), Expect = 1e-13 Identities = 42/112 (37%), Positives = 64/112 (57%), Gaps = 2/112 (1%) Frame = +3 Query: 2133 SNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVS-- 2306 ++S VGT Y+APE++ G+ DWW+ GV L+E+L G+ PF P ET V++ Sbjct: 870 AHSLVGTPNYIAPEVLLRKGYTQLCDWWSVGVILFEMLVGQPPFLAPTPTETQLKVINWE 929 Query: 2307 QNLRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPFFEGLNWA 2462 L P +S A+DLI L ++RLG GA ++K HPFF ++++ Sbjct: 930 NTLHIPAQVKLSPEARDLITKLCC-SADHRLGR-NGADDLKAHPFFSAIDFS 979
>P36887:KAPCA_PIG cAMP-dependent protein kinase, alpha-catalytic subunit - Sus scrofa| (Pig) Length = 351 Score = 115 bits (287), Expect = 1e-24 Identities = 62/153 (40%), Positives = 93/153 (60%) Frame = +3 Query: 1428 QGPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREI 1607 Q LD F +K LG G G V L + ++ FA+K++D + ++ K++ E+ I Sbjct: 36 QNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHFAMKILDKQKVVKLKQIEHTLNEKRI 95 Query: 1608 LEMLDHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLL 1787 L+ ++ PFL L F ++ +VMEY PGG++ R+ GR F EP ARFY A+++L Sbjct: 96 LQAVNFPFLVKLEYSFKDNSNLYMVMEYVPGGEMFS-HLRRIGR-FSEPHARFYAAQIVL 153 Query: 1788 ALEYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 EYLH L +IYRDLKPEN+L+ G+I ++DF Sbjct: 154 TFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDF 186 Score = 86.3 bits (212), Expect = 6e-16 Identities = 50/124 (40%), Positives = 67/124 (54%), Gaps = 3/124 (2%) Frame = +3 Query: 2124 EARSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVV 2303 + R+ + GT EYLAPEII G+ AVDWW GV +YE+ G PF + +V Sbjct: 193 KGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIV 252 Query: 2304 SQNLRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLR-GAAEIKQHPFFEGLNWALI--RS 2474 S +RFP + SS+ KDL+R LL + R G L+ G +IK H +F +W I R Sbjct: 253 SGKVRFPSH--FSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRK 310 Query: 2475 VAPP 2486 V P Sbjct: 311 VEAP 314
>Q8MJ44:KAPCA_CANFA cAMP-dependent protein kinase, alpha-catalytic subunit - Canis| familiaris (Dog) Length = 350 Score = 115 bits (287), Expect = 1e-24 Identities = 62/153 (40%), Positives = 93/153 (60%) Frame = +3 Query: 1428 QGPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREI 1607 Q LD F +K LG G G V L + ++ FA+K++D + ++ K++ E+ I Sbjct: 35 QNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHFAMKILDKQKVVKLKQIEHTLNEKRI 94 Query: 1608 LEMLDHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLL 1787 L+ ++ PFL L F ++ +VMEY PGG++ R+ GR F EP ARFY A+++L Sbjct: 95 LQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFS-HLRRIGR-FSEPHARFYAAQIVL 152 Query: 1788 ALEYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 EYLH L +IYRDLKPEN+L+ G+I ++DF Sbjct: 153 TFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDF 185 Score = 86.3 bits (212), Expect = 6e-16 Identities = 50/124 (40%), Positives = 67/124 (54%), Gaps = 3/124 (2%) Frame = +3 Query: 2124 EARSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVV 2303 + R+ + GT EYLAPEII G+ AVDWW GV +YE+ G PF + +V Sbjct: 192 KGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIV 251 Query: 2304 SQNLRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLR-GAAEIKQHPFFEGLNWALI--RS 2474 S +RFP + SS+ KDL+R LL + R G L+ G +IK H +F +W I R Sbjct: 252 SGKVRFPSH--FSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRK 309 Query: 2475 VAPP 2486 V P Sbjct: 310 VEAP 313
>P00517:KAPCA_BOVIN cAMP-dependent protein kinase, alpha-catalytic subunit - Bos taurus| (Bovine) Length = 351 Score = 115 bits (287), Expect = 1e-24 Identities = 61/153 (39%), Positives = 94/153 (61%) Frame = +3 Query: 1428 QGPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREI 1607 Q LD F +K LG G G V L + +++ +A+K++D + ++ K++ E+ I Sbjct: 36 QNTAHLDQFERIKTLGTGSFGRVMLVKHMETGNHYAMKILDKQKVVKLKQIEHTLNEKRI 95 Query: 1608 LEMLDHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLL 1787 L+ ++ PFL L F ++ +VMEY PGG++ R+ GR F EP ARFY A+++L Sbjct: 96 LQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFS-HLRRIGR-FSEPHARFYAAQIVL 153 Query: 1788 ALEYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 EYLH L +IYRDLKPEN+L+ G+I ++DF Sbjct: 154 TFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDF 186 Score = 86.3 bits (212), Expect = 6e-16 Identities = 50/124 (40%), Positives = 67/124 (54%), Gaps = 3/124 (2%) Frame = +3 Query: 2124 EARSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVV 2303 + R+ + GT EYLAPEII G+ AVDWW GV +YE+ G PF + +V Sbjct: 193 KGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIV 252 Query: 2304 SQNLRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLR-GAAEIKQHPFFEGLNWALI--RS 2474 S +RFP + SS+ KDL+R LL + R G L+ G +IK H +F +W I R Sbjct: 253 SGKVRFPSH--FSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRK 310 Query: 2475 VAPP 2486 V P Sbjct: 311 VEAP 314
>Q8R4V0:SGK3_RAT Serine/threonine-protein kinase Sgk3 - Rattus norvegicus (Rat)| Length = 496 Score = 114 bits (286), Expect = 2e-24 Identities = 63/147 (42%), Positives = 91/147 (61%), Gaps = 1/147 (0%) Frame = +3 Query: 1449 NFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREIL-EMLDH 1625 +F LK +G G G V LA+ +A+KV+ + +++RK+ AER +L + + H Sbjct: 161 DFDFLKVIGKGSFGKVLLAKRKLDGKFYAVKVLQKKIVLNRKEQKHIMAERNVLLKNVKH 220 Query: 1626 PFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALEYLH 1805 PFL L+ F T V+++ GG+L QR+ RSFPEP ARFY AE+ AL YLH Sbjct: 221 PFLVGLHYSFQTTEKLYFVLDFVNGGELFFHLQRE--RSFPEPRARFYAAEIASALGYLH 278 Query: 1806 MLGVIYRDLKPENILVRDDGHIMLSDF 1886 + ++YRDLKPENIL+ GH++L+DF Sbjct: 279 SIKIVYRDLKPENILLDSMGHVVLTDF 305 Score = 92.8 bits (229), Expect = 7e-18 Identities = 50/123 (40%), Positives = 66/123 (53%), Gaps = 1/123 (0%) Frame = +3 Query: 2133 SNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQN 2312 + +F GT EYLAPE+I+ + VDWW G LYE+LYG PF E N++ + Sbjct: 318 TTTFCGTPEYLAPEVIRKQPYDRTVDWWCLGAVLYEMLYGLPPFYCRDVAEMYDNILHKP 377 Query: 2313 LRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPFFEGLNWA-LIRSVAPPE 2489 L P VS A ++ LL K +NRLG EI+ HPFFE L+W L++ PP Sbjct: 378 LNL--RPGVSLTAWSILEELLEKNRQNRLGAKEDFLEIQNHPFFESLSWTDLVQKKIPPP 435 Query: 2490 TRP 2498 P Sbjct: 436 FNP 438
>Q9ERE3:SGK3_MOUSE Serine/threonine-protein kinase Sgk3 - Mus musculus (Mouse)| Length = 496 Score = 114 bits (286), Expect = 2e-24 Identities = 63/147 (42%), Positives = 91/147 (61%), Gaps = 1/147 (0%) Frame = +3 Query: 1449 NFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREIL-EMLDH 1625 +F LK +G G G V LA+ +A+KV+ + +++RK+ AER +L + + H Sbjct: 161 DFDFLKVIGKGSFGKVLLAKRKLDGKFYAVKVLQKKIVLNRKEQKHIMAERNVLLKNVKH 220 Query: 1626 PFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALEYLH 1805 PFL L+ F T V+++ GG+L QR+ RSFPEP ARFY AE+ AL YLH Sbjct: 221 PFLVGLHYSFQTTEKLYFVLDFVNGGELFFHLQRE--RSFPEPRARFYAAEIASALGYLH 278 Query: 1806 MLGVIYRDLKPENILVRDDGHIMLSDF 1886 + ++YRDLKPENIL+ GH++L+DF Sbjct: 279 SIKIVYRDLKPENILLDSMGHVVLTDF 305 Score = 93.6 bits (231), Expect = 4e-18 Identities = 50/123 (40%), Positives = 67/123 (54%), Gaps = 1/123 (0%) Frame = +3 Query: 2133 SNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQN 2312 + +F GT EYLAPE+I+ + + VDWW G LYE+LYG PF E N++ + Sbjct: 318 TTTFCGTPEYLAPEVIRKQPYDNTVDWWCLGAVLYEMLYGLPPFYCRDVAEMYDNILHKP 377 Query: 2313 LRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPFFEGLNWA-LIRSVAPPE 2489 L P VS A ++ LL K +NRLG EI+ HPFFE L+W L++ PP Sbjct: 378 LNL--RPGVSLTAWSILEELLEKNRQNRLGAKEDFLEIQNHPFFESLSWTDLVQKKIPPP 435 Query: 2490 TRP 2498 P Sbjct: 436 FNP 438
>Q5R4K9:KPCI_PONPY Protein kinase C iota type - Pongo pygmaeus (Orangutan)| Length = 587 Score = 114 bits (286), Expect = 2e-24 Identities = 66/160 (41%), Positives = 94/160 (58%), Gaps = 1/160 (0%) Frame = +3 Query: 1410 RQLALQQGPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRA 1589 R+ LGL +F LL+ +G G V L L +D ++A+KV+ E + + + Sbjct: 231 RESGKASSSLGLQDFDLLRVIGRGSYAKVLLVRLKKTDRIYAMKVVKKELVNDDEDIDWV 290 Query: 1590 QAEREILEML-DHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARF 1766 Q E+ + E +HPFL L++ F T++ V+EY GGDL QRQ R PE ARF Sbjct: 291 QTEKHVFEQASNHPFLVGLHSCFQTESRLFFVIEYVNGGDLMFHMQRQ--RKLPEEHARF 348 Query: 1767 YVAEVLLALEYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 Y AE+ LAL YLH G+IYRDLK +N+L+ +GHI L+D+ Sbjct: 349 YSAEISLALNYLHERGIIYRDLKLDNVLLDSEGHIKLTDY 388 Score = 86.3 bits (212), Expect = 6e-16 Identities = 44/131 (33%), Positives = 77/131 (58%), Gaps = 13/131 (9%) Frame = +3 Query: 2133 SNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGN---------DE 2285 +++F GT Y+APEI++G+ +G +VDWW GV ++E++ GR+PF G+ D Sbjct: 401 TSTFCGTPNYIAPEILRGEDYGFSVDWWALGVLMFEMMAGRSPFDIVGSSDNPDQNTEDY 460 Query: 2286 TLANVVSQNLRFPDNPVVSSNAKDLIRGLLVKEPENRLG--TLRGAAEIKQHPFFEGLNW 2459 ++ + +R P + +S A +++ L K+P+ RLG G A+I+ HPFF ++W Sbjct: 461 LFQVILEKQIRIPRS--LSVKAASVLKSFLNKDPKERLGCHPQTGFADIQGHPFFRNVDW 518 Query: 2460 ALI--RSVAPP 2486 ++ + V PP Sbjct: 519 DMMEQKQVVPP 529
>Q62074:KPCI_MOUSE Protein kinase C iota type - Mus musculus (Mouse)| Length = 586 Score = 114 bits (286), Expect = 2e-24 Identities = 66/160 (41%), Positives = 94/160 (58%), Gaps = 1/160 (0%) Frame = +3 Query: 1410 RQLALQQGPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRA 1589 R+ LGL +F LL+ +G G V L L +D ++A+KV+ E + + + Sbjct: 230 RESGKASSSLGLQDFDLLRVIGRGSYAKVLLVRLKKTDRIYAMKVVKKELVNDDEDIDWV 289 Query: 1590 QAEREILEML-DHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARF 1766 Q E+ + E +HPFL L++ F T++ V+EY GGDL QRQ R PE ARF Sbjct: 290 QTEKHVFEQASNHPFLVGLHSCFQTESRLFFVIEYVNGGDLMFHMQRQ--RKLPEEHARF 347 Query: 1767 YVAEVLLALEYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 Y AE+ LAL YLH G+IYRDLK +N+L+ +GHI L+D+ Sbjct: 348 YSAEISLALNYLHERGIIYRDLKLDNVLLDSEGHIKLTDY 387 Score = 86.3 bits (212), Expect = 6e-16 Identities = 44/131 (33%), Positives = 77/131 (58%), Gaps = 13/131 (9%) Frame = +3 Query: 2133 SNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGN---------DE 2285 +++F GT Y+APEI++G+ +G +VDWW GV ++E++ GR+PF G+ D Sbjct: 400 TSTFCGTPNYIAPEILRGEDYGFSVDWWALGVLMFEMMAGRSPFDIVGSSDNPDQNTEDY 459 Query: 2286 TLANVVSQNLRFPDNPVVSSNAKDLIRGLLVKEPENRLG--TLRGAAEIKQHPFFEGLNW 2459 ++ + +R P + +S A +++ L K+P+ RLG G A+I+ HPFF ++W Sbjct: 460 LFQVILEKQIRIPRS--LSVKAASVLKSFLNKDPKERLGCHPQTGFADIQGHPFFRNVDW 517 Query: 2460 ALI--RSVAPP 2486 ++ + V PP Sbjct: 518 DMMEQKQVVPP 528
>P41743:KPCI_HUMAN Protein kinase C iota type - Homo sapiens (Human)| Length = 587 Score = 114 bits (286), Expect = 2e-24 Identities = 66/160 (41%), Positives = 94/160 (58%), Gaps = 1/160 (0%) Frame = +3 Query: 1410 RQLALQQGPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRA 1589 R+ LGL +F LL+ +G G V L L +D ++A+KV+ E + + + Sbjct: 231 RESGKASSSLGLQDFDLLRVIGRGSYAKVLLVRLKKTDRIYAMKVVKKELVNDDEDIDWV 290 Query: 1590 QAEREILEML-DHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARF 1766 Q E+ + E +HPFL L++ F T++ V+EY GGDL QRQ R PE ARF Sbjct: 291 QTEKHVFEQASNHPFLVGLHSCFQTESRLFFVIEYVNGGDLMFHMQRQ--RKLPEEHARF 348 Query: 1767 YVAEVLLALEYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 Y AE+ LAL YLH G+IYRDLK +N+L+ +GHI L+D+ Sbjct: 349 YSAEISLALNYLHERGIIYRDLKLDNVLLDSEGHIKLTDY 388 Score = 86.3 bits (212), Expect = 6e-16 Identities = 44/131 (33%), Positives = 77/131 (58%), Gaps = 13/131 (9%) Frame = +3 Query: 2133 SNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGN---------DE 2285 +++F GT Y+APEI++G+ +G +VDWW GV ++E++ GR+PF G+ D Sbjct: 401 TSTFCGTPNYIAPEILRGEDYGFSVDWWALGVLMFEMMAGRSPFDIVGSSDNPDQNTEDY 460 Query: 2286 TLANVVSQNLRFPDNPVVSSNAKDLIRGLLVKEPENRLG--TLRGAAEIKQHPFFEGLNW 2459 ++ + +R P + +S A +++ L K+P+ RLG G A+I+ HPFF ++W Sbjct: 461 LFQVILEKQIRIPRS--LSVKAASVLKSFLNKDPKERLGCHPQTGFADIQGHPFFRNVDW 518 Query: 2460 ALI--RSVAPP 2486 ++ + V PP Sbjct: 519 DMMEQKQVVPP 529
>Q99014:KPC1_TRIRE Protein kinase C-like - Trichoderma reesei (Hypocrea jecorina)| Length = 1139 Score = 114 bits (286), Expect = 2e-24 Identities = 67/153 (43%), Positives = 93/153 (60%), Gaps = 3/153 (1%) Frame = +3 Query: 1437 LGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEM 1616 +GLD+F L LG G+ G V LAE S LFA+KV+ E++I ++ ++E+ + + Sbjct: 809 IGLDHFNFLAVLGKGNFGKVMLAETKRSKRLFAIKVLKKEFIIENDEVESIKSEKRVFLI 868 Query: 1617 LD---HPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLL 1787 + HPFL L+A F T+ VMEY GGDL + QR F A+FY AEV L Sbjct: 869 ANRERHPFLTNLHACFQTETRVYFVMEYISGGDLMLHIQRG---QFGTKRAQFYAAEVCL 925 Query: 1788 ALEYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 AL+Y H GVIYRDLK +NI++ DGHI ++D+ Sbjct: 926 ALKYFHENGVIYRDLKLDNIMLTLDGHIKIADY 958 Score = 87.8 bits (216), Expect = 2e-16 Identities = 44/121 (36%), Positives = 73/121 (60%), Gaps = 3/121 (2%) Frame = +3 Query: 2133 SNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQN 2312 +++F GT E++APEI+ +G AVDWW FGV +Y++L ++PFRG DE +++ Sbjct: 971 TSTFCGTPEFMAPEILLDKKYGRAVDWWAFGVLIYQMLLQQSPFRGEDEDEIYDAILADE 1030 Query: 2313 LRFPDNPVVSSNAKDLIRGLLVKEPENRLGT-LRGAAEIKQHPFFEGLNWALI--RSVAP 2483 +P + + ++ +++ LL +EP+ RLG+ A E+ PFF +NW I + V P Sbjct: 1031 PLYPIH--MPRDSVSILQKLLTREPDQRLGSGPTDAQEVMSQPFFRNINWDDIYHKRVQP 1088 Query: 2484 P 2486 P Sbjct: 1089 P 1089
>Q9MZD9:KAPCA_SHEEP cAMP-dependent protein kinase, alpha-catalytic subunit - Ovis aries| (Sheep) Length = 351 Score = 114 bits (286), Expect = 2e-24 Identities = 61/153 (39%), Positives = 93/153 (60%) Frame = +3 Query: 1428 QGPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREI 1607 Q LD F +K LG G G V L + ++ +A+K++D + ++ K++ E+ I Sbjct: 36 QNTAHLDQFERIKTLGTGSFGRVMLVKHTETGNHYAMKILDKQKVVKLKQIEHTLNEKRI 95 Query: 1608 LEMLDHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLL 1787 L+ ++ PFL L F ++ +VMEY PGG++ R+ GR F EP ARFY A+++L Sbjct: 96 LQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFS-HLRRIGR-FSEPHARFYAAQIVL 153 Query: 1788 ALEYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 EYLH L +IYRDLKPEN+L+ G+I ++DF Sbjct: 154 TFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDF 186 Score = 86.3 bits (212), Expect = 6e-16 Identities = 50/124 (40%), Positives = 67/124 (54%), Gaps = 3/124 (2%) Frame = +3 Query: 2124 EARSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVV 2303 + R+ + GT EYLAPEII G+ AVDWW GV +YE+ G PF + +V Sbjct: 193 KGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIV 252 Query: 2304 SQNLRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLR-GAAEIKQHPFFEGLNWALI--RS 2474 S +RFP + SS+ KDL+R LL + R G L+ G +IK H +F +W I R Sbjct: 253 SGKVRFPSH--FSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRK 310 Query: 2475 VAPP 2486 V P Sbjct: 311 VEAP 314
>P27791:KAPCA_RAT cAMP-dependent protein kinase, alpha-catalytic subunit - Rattus| norvegicus (Rat) Length = 351 Score = 114 bits (286), Expect = 2e-24 Identities = 62/153 (40%), Positives = 94/153 (61%) Frame = +3 Query: 1428 QGPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREI 1607 Q LD+F +K LG G G V L + +S +A+K++D + ++ K++ E+ I Sbjct: 36 QNTAQLDHFDRIKTLGTGSFGRVMLVKHKESGNHYAMKILDKQKVVKLKQIEHTLNEKRI 95 Query: 1608 LEMLDHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLL 1787 L+ ++ PFL L F ++ +VMEY PGG++ R+ GR F EP ARFY A+++L Sbjct: 96 LQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFS-HLRRIGR-FSEPHARFYAAQIVL 153 Query: 1788 ALEYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 EYLH L +IYRDLKPEN+L+ G+I ++DF Sbjct: 154 TFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDF 186 Score = 86.3 bits (212), Expect = 6e-16 Identities = 50/124 (40%), Positives = 67/124 (54%), Gaps = 3/124 (2%) Frame = +3 Query: 2124 EARSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVV 2303 + R+ + GT EYLAPEII G+ AVDWW GV +YE+ G PF + +V Sbjct: 193 KGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIV 252 Query: 2304 SQNLRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLR-GAAEIKQHPFFEGLNWALI--RS 2474 S +RFP + SS+ KDL+R LL + R G L+ G +IK H +F +W I R Sbjct: 253 SGKVRFPSH--FSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRK 310 Query: 2475 VAPP 2486 V P Sbjct: 311 VEAP 314
>Q5F3L1:KS6A5_CHICK Ribosomal protein S6 kinase alpha-5 - Gallus gallus (Chicken)| Length = 789 Score = 114 bits (285), Expect = 2e-24 Identities = 66/156 (42%), Positives = 98/156 (62%), Gaps = 6/156 (3%) Frame = +3 Query: 1437 LGLDNFRLLKRLGCGDIGTVYLAELV---DSDCLFALKVMDIEYLISRKKMLR-AQAERE 1604 +G++NF LLK LG G G V+L V D+ L+A+KV+ ++ + K + ER+ Sbjct: 34 VGIENFELLKVLGTGAYGKVFLVRKVSGHDAGKLYAMKVLKKATIVQKAKTTEHTRTERQ 93 Query: 1605 ILEML-DHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHV-LRQRQPGRSFPEPSARFYVAE 1778 +LE + PFL TL+ F TD L+++Y GG+L L QR+ F E + Y+ E Sbjct: 94 VLEHIRQSPFLVTLHYAFQTDTKLHLILDYINGGELFTHLSQRE---RFSENEVQIYIGE 150 Query: 1779 VLLALEYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 ++LALE+LH LG+IYRD+K ENIL+ DGH++L+DF Sbjct: 151 IVLALEHLHKLGIIYRDIKLENILLDSDGHVVLTDF 186 Score = 100 bits (248), Expect = 4e-20 Identities = 53/115 (46%), Positives = 75/115 (65%), Gaps = 5/115 (4%) Frame = +3 Query: 2130 RSNSFVGTHEYLAPEIIKGD--GHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVV 2303 R+ SF GT EY+AP+I++G GH AVDWW+ GV +YELL G +PF G + A + Sbjct: 199 RAYSFCGTIEYMAPDIVRGGDTGHDKAVDWWSVGVLMYELLTGASPFTVDGEKNSQAEIS 258 Query: 2304 SQNLRF--PDNPVVSSNAKDLIRGLLVKEPENRLGT-LRGAAEIKQHPFFEGLNW 2459 + L+ P +S+ +KD+I+ LL+K+P+ RLG A EIKQHPFF+ +NW Sbjct: 259 RRILKSEPPYPQEMSALSKDIIQRLLMKDPKKRLGCGPTDADEIKQHPFFQNINW 313 Score = 58.5 bits (140), Expect = 1e-07 Identities = 50/178 (28%), Positives = 82/178 (46%), Gaps = 6/178 (3%) Frame = +3 Query: 1371 RPHMVKDLCWITIRQLALQQGPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMD 1550 R M+KD + +L L++ PLG +F + ++ CL + Sbjct: 400 RSAMMKDSPFFQHYELDLKEKPLGEGSFSICRK------------------CLHKKTSQE 441 Query: 1551 IEYLISRKKMLRAQAEREILEML---DHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLR 1721 I K+M A +REI + HP + L+ + + LVME GG+L L Sbjct: 442 YAVKIISKRM-EANTQREITALKLCEGHPNVVKLHEVYHDQLHTFLVMELLKGGEL--LE 498 Query: 1722 QRQPGRSFPEPSARFYVAEVLLALEYLHMLGVIYRDLKPENILVRDD---GHIMLSDF 1886 + Q + F E A + ++ A+ ++H +GV++RDLKPEN+L D+ I + DF Sbjct: 499 RIQKKQHFSETEASHIMRRLVSAVSHMHDVGVVHRDLKPENLLFTDETDNSEIKIIDF 556 Score = 51.2 bits (121), Expect = 2e-05 Identities = 28/92 (30%), Positives = 43/92 (46%), Gaps = 9/92 (9%) Frame = +3 Query: 2151 THEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQNLRFPDN 2330 T Y APE+ +G+ + D W+ GV LY +L G+ PF+ T + + + Sbjct: 575 TLHYAAPELFNHNGYDESCDLWSLGVILYTMLSGQVPFQSQDKSLTCTSALEIMKKIKKG 634 Query: 2331 PV---------VSSNAKDLIRGLLVKEPENRL 2399 VS AK+LI+GLL +P R+ Sbjct: 635 EFSFEGEAWKNVSEEAKELIQGLLTVDPNKRI 666
>P09216:KPCE_RAT Protein kinase C epsilon type - Rattus norvegicus (Rat)| Length = 737 Score = 114 bits (285), Expect = 2e-24 Identities = 68/151 (45%), Positives = 88/151 (58%), Gaps = 1/151 (0%) Frame = +3 Query: 1437 LGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEM 1616 LGLD F +K LG G G V LAEL D ++A+KV+ + ++ + E+ IL + Sbjct: 403 LGLDEFNFIKVLGKGSFGKVMLAELKGKDEVYAVKVLKKDVILQDDDVDCTMTEKRILAL 462 Query: 1617 L-DHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLAL 1793 HP+L LY F T + VMEY GGDL + Q Q R F EP + FY AEV AL Sbjct: 463 ARKHPYLTQLYCCFQTKDRLFFVMEYVNGGDL--MFQIQRSRKFDEPRSGFYAAEVTSAL 520 Query: 1794 EYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 +LH GVIYRDLK +NIL+ +GH L+DF Sbjct: 521 MFLHQHGVIYRDLKLDNILLDAEGHSKLADF 551 Score = 89.7 bits (221), Expect = 6e-17 Identities = 41/123 (33%), Positives = 72/123 (58%), Gaps = 5/123 (4%) Frame = +3 Query: 2133 SNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQN 2312 + +F GT +Y+APEI++ +G +VDWW GV +YE++ G+ PF D+ +++ + Sbjct: 564 TTTFCGTPDYIAPEILQELEYGPSVDWWALGVLMYEMMAGQPPFEADNEDDLFESILHDD 623 Query: 2313 LRFPDNPVVSSNAKDLIRGLLVKEPENRLGTL---RGAAEIKQHPFFEGLNWALI--RSV 2477 + +P +S A +++ + K P RLG + G IKQHPFF+ ++W L+ + + Sbjct: 624 VLYP--VWLSKEAVSILKAFMTKNPHKRLGCVAAQNGEDAIKQHPFFKEIDWVLLEQKKM 681 Query: 2478 APP 2486 PP Sbjct: 682 KPP 684
>Q16975:KPC2_APLCA Calcium-independent protein kinase C - Aplysia californica| (California sea hare) Length = 743 Score = 114 bits (285), Expect = 2e-24 Identities = 80/224 (35%), Positives = 112/224 (50%), Gaps = 14/224 (6%) Frame = +3 Query: 1257 LTLEKGERSQNSKSSISEYGCSTSI-----SDESQFGLYGYNN--------RPHMVKDLC 1397 L++ + S N S + E S+ I SDE+Q G G + H Sbjct: 325 LSISESHESPNKSSPMHERSLSSPIPVIQDSDEAQPGEMGLPSDSLPVNASNEHQGSRTR 384 Query: 1398 WITIRQLALQQGPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKK 1577 + + + L +F +K LG G G V LAE +D ++A+KV+ + +I Sbjct: 385 SPSSDRSRSHHSRISLHDFNFIKVLGKGSFGKVMLAEKKGTDEVYAIKVLKKDVIIQDDD 444 Query: 1578 MLRAQAEREILEM-LDHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEP 1754 + E+ IL + HPFL L++ F T VMEY GGDL + Q Q R F EP Sbjct: 445 VECTMTEKRILALSAKHPFLTALHSSFQTKERLFFVMEYVNGGDL--MFQIQRARKFDEP 502 Query: 1755 SARFYVAEVLLALEYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 ARFY AEV LAL +LH G+IYRDLK +NIL+ +GH ++DF Sbjct: 503 RARFYAAEVTLALMFLHRHGIIYRDLKLDNILLDAEGHCKIADF 546 Score = 80.5 bits (197), Expect = 4e-14 Identities = 42/124 (33%), Positives = 72/124 (58%), Gaps = 6/124 (4%) Frame = +3 Query: 2133 SNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQN 2312 + +F GT +Y+APEI++ + ++VDWW GV +YE++ G+ PF D+ +++ + Sbjct: 559 TQTFCGTPDYIAPEILQELKYDASVDWWALGVLMYEMMAGQPPFEADNEDDLFESILHDD 618 Query: 2313 LRFPDNPVVSSNAKDLIRGLLVKEPENRLG--TLRGAAE-IKQHPFF-EGLNWALI--RS 2474 + +P +S A +++G + K P RLG T +G + I HPFF E ++W + R Sbjct: 619 VLYP--VWLSKEAVSILKGFMTKNPAKRLGCVTTQGCEKAILVHPFFHEKIDWEALEQRK 676 Query: 2475 VAPP 2486 V PP Sbjct: 677 VKPP 680
>Q6TGC6:CBK1_PNECA Serine/threonine-protein kinase CBK1 - Pneumocystis carinii| Length = 507 Score = 114 bits (285), Expect = 2e-24 Identities = 59/157 (37%), Positives = 95/157 (60%) Frame = +3 Query: 1416 LALQQGPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQA 1595 L L++ L L++F +K +G G G V L + +D+ ++A+K + + + ++ +A Sbjct: 114 LRLRRTKLSLNDFHTVKVIGKGAFGEVRLVQKIDTGKIYAMKTLLKSEMFKKDQLAHVKA 173 Query: 1596 EREILEMLDHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVA 1775 ER++L D P++ +LY F L+ME+ PGGDL + + +F E RFY+A Sbjct: 174 ERDVLAESDSPWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIKYD--TFSEDVTRFYIA 231 Query: 1776 EVLLALEYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 E +LA+E +H LG I+RD+KP+NIL+ GHI LSDF Sbjct: 232 ECILAIEAVHKLGFIHRDIKPDNILIDKTGHIKLSDF 268 Score = 96.3 bits (238), Expect = 6e-19 Identities = 51/118 (43%), Positives = 70/118 (59%), Gaps = 2/118 (1%) Frame = +3 Query: 2139 SFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVS--QN 2312 S VGT +Y+APEI G+G DWW+ G ++E L G PF ET +++ +N Sbjct: 330 STVGTPDYIAPEIFTQHGYGQECDWWSLGAIMFECLIGWPPFCSENAHETYRKIINWREN 389 Query: 2313 LRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPFFEGLNWALIRSVAPP 2486 L FP++ +S+ A+DLIR LL + RLG GA +IK HPFF G+NW IR + P Sbjct: 390 LYFPEDLHLSAEAEDLIRKLLT-SADQRLGRY-GANDIKLHPFFRGVNWDTIREINAP 445
>P87253:KPC1_NEUCR Protein kinase C-like - Neurospora crassa| Length = 1142 Score = 114 bits (284), Expect = 3e-24 Identities = 67/153 (43%), Positives = 93/153 (60%), Gaps = 3/153 (1%) Frame = +3 Query: 1437 LGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEM 1616 +GLD+F L LG G+ G V LAE S L+A+KV+ E++I ++ ++E+ + + Sbjct: 812 IGLDHFNFLAVLGKGNFGKVMLAETKKSRKLYAIKVLKKEFIIENDEVESIRSEKRVFLI 871 Query: 1617 LD---HPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLL 1787 + HPFL L+A F T+ VMEY GGDL + QR F A+FY AEV L Sbjct: 872 ANRERHPFLTNLHACFQTETRVYFVMEYISGGDLMLHIQRG---MFGTKRAQFYAAEVCL 928 Query: 1788 ALEYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 AL+Y H GVIYRDLK +NIL+ DGHI ++D+ Sbjct: 929 ALKYFHENGVIYRDLKLDNILLTLDGHIKIADY 961 Score = 88.2 bits (217), Expect = 2e-16 Identities = 45/121 (37%), Positives = 73/121 (60%), Gaps = 3/121 (2%) Frame = +3 Query: 2133 SNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQN 2312 +++F GT E++APEI+ +G AVDWW FGV +Y++L ++PFRG DE +++ Sbjct: 974 TSTFCGTPEFMAPEILLDKKYGRAVDWWAFGVLIYQMLLQQSPFRGEDEDEIYDAILADE 1033 Query: 2313 LRFPDNPVVSSNAKDLIRGLLVKEPENRLGT-LRGAAEIKQHPFFEGLNWALI--RSVAP 2483 +P + + ++ +++ LL +EP+ RLG+ A EI PFF +NW I + V P Sbjct: 1034 PLYPIH--MPRDSVSILQKLLTREPDQRLGSGPTDAQEIMSQPFFRNINWDDIYHKRVQP 1091 Query: 2484 P 2486 P Sbjct: 1092 P 1092
>Q00078:KPC1_ASPNG Protein kinase C-like - Aspergillus niger| Length = 1096 Score = 114 bits (284), Expect = 3e-24 Identities = 66/153 (43%), Positives = 94/153 (61%), Gaps = 3/153 (1%) Frame = +3 Query: 1437 LGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEM 1616 +GLD+F L LG G+ G V LAE + L+A+KV+ E++I ++ ++E+ + + Sbjct: 766 IGLDHFNFLAVLGKGNFGKVMLAETKSTKRLYAIKVLKKEFIIENDEVESTKSEKRVFMI 825 Query: 1617 LD---HPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLL 1787 + HPFL L+A F T+ VMEY GGDL + QR F A+FY AEVLL Sbjct: 826 ANKERHPFLLNLHACFQTETRVYFVMEYISGGDLMLHIQRG---QFGLKRAQFYAAEVLL 882 Query: 1788 ALEYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 AL+Y H GVIYRDLK +NI++ DGHI ++D+ Sbjct: 883 ALKYFHENGVIYRDLKLDNIMLTLDGHIKVADY 915 Score = 89.0 bits (219), Expect = 1e-16 Identities = 46/123 (37%), Positives = 74/123 (60%), Gaps = 3/123 (2%) Frame = +3 Query: 2127 ARSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVS 2306 A +++F GT E++APEI+ +G AVDWW FGV +Y++L ++PFRG DE +++ Sbjct: 926 ATTSTFCGTPEFMAPEILLDKRYGRAVDWWAFGVLIYQMLLQQSPFRGEDEDEIYDAILA 985 Query: 2307 QNLRFPDNPVVSSNAKDLIRGLLVKEPENRLGT-LRGAAEIKQHPFFEGLNWALI--RSV 2477 +P + + ++ +++ LL +EPE RLG+ A E+ H FF +NW I + V Sbjct: 986 DEPLYPIH--MPRDSVSILQKLLTREPELRLGSGPTDAQEVMSHAFFRNINWDDIYHKRV 1043 Query: 2478 APP 2486 PP Sbjct: 1044 PPP 1046
>P17612:KAPCA_HUMAN cAMP-dependent protein kinase, alpha-catalytic subunit - Homo sapiens| (Human) Length = 351 Score = 114 bits (284), Expect = 3e-24 Identities = 61/153 (39%), Positives = 93/153 (60%) Frame = +3 Query: 1428 QGPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREI 1607 Q LD F +K LG G G V L + ++ +A+K++D + ++ K++ E+ I Sbjct: 36 QNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRI 95 Query: 1608 LEMLDHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLL 1787 L+ ++ PFL L F ++ +VMEY PGG++ R+ GR F EP ARFY A+++L Sbjct: 96 LQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFS-HLRRIGR-FSEPHARFYAAQIVL 153 Query: 1788 ALEYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 EYLH L +IYRDLKPEN+L+ G+I ++DF Sbjct: 154 TFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDF 186 Score = 86.3 bits (212), Expect = 6e-16 Identities = 50/124 (40%), Positives = 67/124 (54%), Gaps = 3/124 (2%) Frame = +3 Query: 2124 EARSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVV 2303 + R+ + GT EYLAPEII G+ AVDWW GV +YE+ G PF + +V Sbjct: 193 KGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIV 252 Query: 2304 SQNLRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLR-GAAEIKQHPFFEGLNWALI--RS 2474 S +RFP + SS+ KDL+R LL + R G L+ G +IK H +F +W I R Sbjct: 253 SGKVRFPSH--FSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRK 310 Query: 2475 VAPP 2486 V P Sbjct: 311 VEAP 314
>P68182:KAPCB_RAT cAMP-dependent protein kinase, beta-catalytic subunit - Rattus| norvegicus (Rat) Length = 351 Score = 113 bits (283), Expect = 4e-24 Identities = 60/149 (40%), Positives = 93/149 (62%) Frame = +3 Query: 1440 GLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEML 1619 GL++F K LG G G V L + ++ +A+K++D + ++ K++ E+ IL+ + Sbjct: 40 GLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAV 99 Query: 1620 DHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALEY 1799 + PFL L F ++ +VMEY PGG++ R+ GR F EP ARFY A+++L EY Sbjct: 100 EFPFLVRLEYSFKDNSNLYMVMEYVPGGEMFS-HLRRIGR-FSEPHARFYAAQIVLTFEY 157 Query: 1800 LHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 LH L +IYRDLKPEN+L+ G+I ++DF Sbjct: 158 LHSLDLIYRDLKPENLLIDHQGYIQVTDF 186 Score = 87.0 bits (214), Expect = 4e-16 Identities = 50/124 (40%), Positives = 68/124 (54%), Gaps = 3/124 (2%) Frame = +3 Query: 2124 EARSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVV 2303 + R+ + GT EYLAPEII G+ AVDWW GV +YE+ G PF + +V Sbjct: 193 KGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIV 252 Query: 2304 SQNLRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLR-GAAEIKQHPFFEGLNWALI--RS 2474 S +RFP + SS+ KDL+R LL + R G L+ G ++IK H +F +W I R Sbjct: 253 SGKVRFPSH--FSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRK 310 Query: 2475 VAPP 2486 V P Sbjct: 311 VEAP 314
>P68181:KAPCB_MOUSE cAMP-dependent protein kinase, beta-catalytic subunit - Mus musculus| (Mouse) Length = 351 Score = 113 bits (283), Expect = 4e-24 Identities = 60/149 (40%), Positives = 93/149 (62%) Frame = +3 Query: 1440 GLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEML 1619 GL++F K LG G G V L + ++ +A+K++D + ++ K++ E+ IL+ + Sbjct: 40 GLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAV 99 Query: 1620 DHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALEY 1799 + PFL L F ++ +VMEY PGG++ R+ GR F EP ARFY A+++L EY Sbjct: 100 EFPFLVRLEYSFKDNSNLYMVMEYVPGGEMFS-HLRRIGR-FSEPHARFYAAQIVLTFEY 157 Query: 1800 LHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 LH L +IYRDLKPEN+L+ G+I ++DF Sbjct: 158 LHSLDLIYRDLKPENLLIDHQGYIQVTDF 186 Score = 87.0 bits (214), Expect = 4e-16 Identities = 50/124 (40%), Positives = 68/124 (54%), Gaps = 3/124 (2%) Frame = +3 Query: 2124 EARSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVV 2303 + R+ + GT EYLAPEII G+ AVDWW GV +YE+ G PF + +V Sbjct: 193 KGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIV 252 Query: 2304 SQNLRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLR-GAAEIKQHPFFEGLNWALI--RS 2474 S +RFP + SS+ KDL+R LL + R G L+ G ++IK H +F +W I R Sbjct: 253 SGKVRFPSH--FSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRK 310 Query: 2475 VAPP 2486 V P Sbjct: 311 VEAP 314
>P22694:KAPCB_HUMAN cAMP-dependent protein kinase, beta-catalytic subunit - Homo sapiens| (Human) Length = 351 Score = 113 bits (283), Expect = 4e-24 Identities = 61/153 (39%), Positives = 94/153 (61%) Frame = +3 Query: 1428 QGPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREI 1607 Q GL++F K LG G G V L + ++ +A+K++D + ++ K++ E+ I Sbjct: 36 QNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRI 95 Query: 1608 LEMLDHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLL 1787 L+ ++ PFL L F ++ +VMEY PGG++ R+ GR F EP ARFY A+++L Sbjct: 96 LQAVNFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFS-HLRRIGR-FSEPHARFYAAQIVL 153 Query: 1788 ALEYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 EYLH L +IYRDLKPEN+L+ G+I ++DF Sbjct: 154 TFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDF 186 Score = 87.0 bits (214), Expect = 4e-16 Identities = 50/124 (40%), Positives = 68/124 (54%), Gaps = 3/124 (2%) Frame = +3 Query: 2124 EARSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVV 2303 + R+ + GT EYLAPEII G+ AVDWW GV +YE+ G PF + +V Sbjct: 193 KGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIV 252 Query: 2304 SQNLRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLR-GAAEIKQHPFFEGLNWALI--RS 2474 S +RFP + SS+ KDL+R LL + R G L+ G ++IK H +F +W I R Sbjct: 253 SGKVRFPSH--FSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRK 310 Query: 2475 VAPP 2486 V P Sbjct: 311 VEAP 314
>P68180:KAPCB_CRIGR cAMP-dependent protein kinase, beta-catalytic subunit - Cricetulus| griseus (Chinese hamster) Length = 351 Score = 113 bits (283), Expect = 4e-24 Identities = 60/149 (40%), Positives = 93/149 (62%) Frame = +3 Query: 1440 GLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEML 1619 GL++F K LG G G V L + ++ +A+K++D + ++ K++ E+ IL+ + Sbjct: 40 GLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAV 99 Query: 1620 DHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALEY 1799 + PFL L F ++ +VMEY PGG++ R+ GR F EP ARFY A+++L EY Sbjct: 100 EFPFLVRLEYSFKDNSNLYMVMEYVPGGEMFS-HLRRIGR-FSEPHARFYAAQIVLTFEY 157 Query: 1800 LHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 LH L +IYRDLKPEN+L+ G+I ++DF Sbjct: 158 LHSLDLIYRDLKPENLLIDHQGYIQVTDF 186 Score = 87.0 bits (214), Expect = 4e-16 Identities = 50/124 (40%), Positives = 68/124 (54%), Gaps = 3/124 (2%) Frame = +3 Query: 2124 EARSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVV 2303 + R+ + GT EYLAPEII G+ AVDWW GV +YE+ G PF + +V Sbjct: 193 KGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIV 252 Query: 2304 SQNLRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLR-GAAEIKQHPFFEGLNWALI--RS 2474 S +RFP + SS+ KDL+R LL + R G L+ G ++IK H +F +W I R Sbjct: 253 SGKVRFPSH--FSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRK 310 Query: 2475 VAPP 2486 V P Sbjct: 311 VEAP 314
>P25321:KAPCA_CRIGR cAMP-dependent protein kinase, alpha-catalytic subunit - Cricetulus| griseus (Chinese hamster) Length = 351 Score = 113 bits (283), Expect = 4e-24 Identities = 61/153 (39%), Positives = 94/153 (61%) Frame = +3 Query: 1428 QGPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREI 1607 Q LD+F +K LG G G V L + ++ +A+K++D + ++ K++ E+ I Sbjct: 36 QNTAQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRI 95 Query: 1608 LEMLDHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLL 1787 L+ ++ PFL L F ++ +VMEY PGG++ R+ GR F EP ARFY A+++L Sbjct: 96 LQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFS-HLRRIGR-FSEPHARFYAAQIVL 153 Query: 1788 ALEYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 EYLH L +IYRDLKPEN+L+ G+I ++DF Sbjct: 154 TFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDF 186 Score = 86.3 bits (212), Expect = 6e-16 Identities = 50/124 (40%), Positives = 67/124 (54%), Gaps = 3/124 (2%) Frame = +3 Query: 2124 EARSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVV 2303 + R+ + GT EYLAPEII G+ AVDWW GV +YE+ G PF + +V Sbjct: 193 KGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIV 252 Query: 2304 SQNLRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLR-GAAEIKQHPFFEGLNWALI--RS 2474 S +RFP + SS+ KDL+R LL + R G L+ G +IK H +F +W I R Sbjct: 253 SGKVRFPSH--FSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRK 310 Query: 2475 VAPP 2486 V P Sbjct: 311 VEAP 314
>Q06226:SGK1_RAT Serine/threonine-protein kinase Sgk1 - Rattus norvegicus (Rat)| Length = 430 Score = 113 bits (282), Expect = 5e-24 Identities = 62/147 (42%), Positives = 89/147 (60%), Gaps = 1/147 (0%) Frame = +3 Query: 1449 NFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREIL-EMLDH 1625 +F LK +G G G V LA + +A+KV+ + ++ +K+ +ER +L + + H Sbjct: 97 DFHFLKVIGKGSFGKVLLARHKAEEAFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKH 156 Query: 1626 PFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALEYLH 1805 PFL L+ F T + V++Y GG+L QR+ R F EP ARFY AE+ AL YLH Sbjct: 157 PFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRE--RCFLEPRARFYAAEIASALGYLH 214 Query: 1806 MLGVIYRDLKPENILVRDDGHIMLSDF 1886 L ++YRDLKPENIL+ GHI+L+DF Sbjct: 215 SLNIVYRDLKPENILLDSQGHIVLTDF 241 Score = 87.8 bits (216), Expect = 2e-16 Identities = 44/120 (36%), Positives = 68/120 (56%), Gaps = 2/120 (1%) Frame = +3 Query: 2133 SNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQN 2312 +++F GT EYLAPE++ + VDWW G LYE+LYG PF E N++++ Sbjct: 254 TSTFCGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKP 313 Query: 2313 LRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPFFEGLNW--ALIRSVAPP 2486 L+ + ++++A+ L+ GLL K+ RLG EIK H FF +NW + + + PP Sbjct: 314 LQLKN---ITNSARHLLEGLLQKDRTKRLGAKDDFMEIKSHIFFSLINWDDLINKKITPP 370
>Q9XT18:SGK1_RABIT Serine/threonine-protein kinase Sgk1 - Oryctolagus cuniculus (Rabbit)| Length = 431 Score = 113 bits (282), Expect = 5e-24 Identities = 62/147 (42%), Positives = 89/147 (60%), Gaps = 1/147 (0%) Frame = +3 Query: 1449 NFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREIL-EMLDH 1625 +F LK +G G G V LA + +A+KV+ + ++ +K+ +ER +L + + H Sbjct: 97 DFHFLKVIGKGSFGKVLLARHKAEEAFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKH 156 Query: 1626 PFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALEYLH 1805 PFL L+ F T + V++Y GG+L QR+ R F EP ARFY AE+ AL YLH Sbjct: 157 PFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRE--RCFLEPRARFYAAEIASALGYLH 214 Query: 1806 MLGVIYRDLKPENILVRDDGHIMLSDF 1886 L ++YRDLKPENIL+ GHI+L+DF Sbjct: 215 SLNIVYRDLKPENILLDSQGHIVLTDF 241 Score = 89.0 bits (219), Expect = 1e-16 Identities = 44/120 (36%), Positives = 68/120 (56%), Gaps = 2/120 (1%) Frame = +3 Query: 2133 SNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQN 2312 +++F GT EYLAPE++ + VDWW G LYE+LYG PF E N++++ Sbjct: 254 TSTFCGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKP 313 Query: 2313 LRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPFFEGLNW--ALIRSVAPP 2486 L+ P ++++A+ L+ GLL K+ RLG EI+ H FF +NW + + + PP Sbjct: 314 LQL--KPNITNSARHLLEGLLQKDRTKRLGAKDDFMEIRNHVFFSLINWDDLINKKITPP 371
>P05383:KAPCB_PIG cAMP-dependent protein kinase, beta-catalytic subunit - Sus scrofa| (Pig) Length = 351 Score = 113 bits (282), Expect = 5e-24 Identities = 60/149 (40%), Positives = 93/149 (62%) Frame = +3 Query: 1440 GLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEML 1619 GL++F K LG G G V L + ++ +A+K++D + ++ K++ E+ IL+ + Sbjct: 40 GLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAV 99 Query: 1620 DHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALEY 1799 + PFL L F ++ +VMEY PGG++ R+ GR F EP ARFY A+++L EY Sbjct: 100 NFPFLVRLEFSFKDNSNLYMVMEYVPGGEMFS-HLRRIGR-FSEPHARFYAAQIVLTFEY 157 Query: 1800 LHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 LH L +IYRDLKPEN+L+ G+I ++DF Sbjct: 158 LHSLDLIYRDLKPENLLIDHQGYIQVTDF 186 Score = 87.0 bits (214), Expect = 4e-16 Identities = 50/124 (40%), Positives = 68/124 (54%), Gaps = 3/124 (2%) Frame = +3 Query: 2124 EARSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVV 2303 + R+ + GT EYLAPEII G+ AVDWW GV +YE+ G PF + +V Sbjct: 193 KGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIV 252 Query: 2304 SQNLRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLR-GAAEIKQHPFFEGLNWALI--RS 2474 S +RFP + SS+ KDL+R LL + R G L+ G ++IK H +F +W I R Sbjct: 253 SGKVRFPSH--FSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRK 310 Query: 2475 VAPP 2486 V P Sbjct: 311 VEAP 314
>Q9WVC6:SGK1_MOUSE Serine/threonine-protein kinase Sgk1 - Mus musculus (Mouse)| Length = 431 Score = 112 bits (281), Expect = 6e-24 Identities = 62/147 (42%), Positives = 89/147 (60%), Gaps = 1/147 (0%) Frame = +3 Query: 1449 NFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREIL-EMLDH 1625 +F LK +G G G V LA + +A+KV+ + ++ +K+ +ER +L + + H Sbjct: 97 DFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKH 156 Query: 1626 PFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALEYLH 1805 PFL L+ F T + V++Y GG+L QR+ R F EP ARFY AE+ AL YLH Sbjct: 157 PFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRE--RCFLEPRARFYAAEIASALGYLH 214 Query: 1806 MLGVIYRDLKPENILVRDDGHIMLSDF 1886 L ++YRDLKPENIL+ GHI+L+DF Sbjct: 215 SLNIVYRDLKPENILLDSQGHIVLTDF 241 Score = 89.7 bits (221), Expect = 6e-17 Identities = 45/120 (37%), Positives = 68/120 (56%), Gaps = 2/120 (1%) Frame = +3 Query: 2133 SNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQN 2312 +++F GT EYLAPE++ + VDWW G LYE+LYG PF E N++++ Sbjct: 254 TSTFCGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKP 313 Query: 2313 LRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPFFEGLNW--ALIRSVAPP 2486 L+ P ++++A+ L+ GLL K+ RLG EIK H FF +NW + + + PP Sbjct: 314 LQL--KPNITNSARHLLEGLLQKDRTKRLGAKDDFMEIKSHIFFSLINWDDLINKKITPP 371
>O00141:SGK1_HUMAN Serine/threonine-protein kinase Sgk1 - Homo sapiens (Human)| Length = 431 Score = 112 bits (281), Expect = 6e-24 Identities = 62/147 (42%), Positives = 89/147 (60%), Gaps = 1/147 (0%) Frame = +3 Query: 1449 NFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREIL-EMLDH 1625 +F LK +G G G V LA + +A+KV+ + ++ +K+ +ER +L + + H Sbjct: 97 DFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKH 156 Query: 1626 PFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALEYLH 1805 PFL L+ F T + V++Y GG+L QR+ R F EP ARFY AE+ AL YLH Sbjct: 157 PFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRE--RCFLEPRARFYAAEIASALGYLH 214 Query: 1806 MLGVIYRDLKPENILVRDDGHIMLSDF 1886 L ++YRDLKPENIL+ GHI+L+DF Sbjct: 215 SLNIVYRDLKPENILLDSQGHIVLTDF 241 Score = 90.1 bits (222), Expect = 4e-17 Identities = 45/120 (37%), Positives = 68/120 (56%), Gaps = 2/120 (1%) Frame = +3 Query: 2133 SNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQN 2312 +++F GT EYLAPE++ + VDWW G LYE+LYG PF E N++++ Sbjct: 254 TSTFCGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKP 313 Query: 2313 LRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPFFEGLNW--ALIRSVAPP 2486 L+ P ++++A+ L+ GLL K+ RLG EIK H FF +NW + + + PP Sbjct: 314 LQL--KPNITNSARHLLEGLLQKDRTKRLGAKDDFMEIKSHVFFSLINWDDLINKKITPP 371
>P18652:KS6AA_CHICK Ribosomal protein S6 kinase 2 alpha - Gallus gallus (Chicken)| Length = 752 Score = 112 bits (281), Expect = 6e-24 Identities = 63/148 (42%), Positives = 94/148 (63%), Gaps = 3/148 (2%) Frame = +3 Query: 1452 FRLLKRLGCGDIGTVYLAELV---DSDCLFALKVMDIEYLISRKKMLRAQAEREILEMLD 1622 F LLK LG G G V+L + DS+ L+A+KV+ L R ++ R + ER+IL ++ Sbjct: 80 FELLKVLGQGSFGKVFLVRKITPPDSNHLYAMKVLKKATLKVRDRV-RTKIERDILADVN 138 Query: 1623 HPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALEYL 1802 HPF+ L+ F T+ L++++ GGDL ++ F E +FY+AE+ L L++L Sbjct: 139 HPFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEV--MFTEEDVKFYLAELALGLDHL 196 Query: 1803 HMLGVIYRDLKPENILVRDDGHIMLSDF 1886 H LG+IYRDLKPENIL+ ++GHI L+DF Sbjct: 197 HSLGIIYRDLKPENILLDEEGHIKLTDF 224 Score = 103 bits (257), Expect = 4e-21 Identities = 49/124 (39%), Positives = 76/124 (61%), Gaps = 3/124 (2%) Frame = +3 Query: 2124 EARSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVV 2303 E ++ SF GT EY+APE++ GH + DWW++GV ++E+L G PF+G ET+ ++ Sbjct: 234 EKKAYSFCGTVEYMAPEVVNRQGHSHSADWWSYGVLMFEMLTGSLPFQGKDRKETMTLIL 293 Query: 2304 SQNLRFPDNPVVSSNAKDLIRGLLVKEPENRLGT-LRGAAEIKQHPFFEGLNWALI--RS 2474 L P +S+ A+ L+R L + P NRLG+ GA EIK+HPF+ ++W + R Sbjct: 294 KAKLGMPQ--FLSAEAQSLLRALFKRNPANRLGSGPDGAEEIKRHPFYSTIDWNKLYRRE 351 Query: 2475 VAPP 2486 + PP Sbjct: 352 IKPP 355 Score = 53.5 bits (127), Expect = 5e-06 Identities = 36/104 (34%), Positives = 54/104 (51%), Gaps = 7/104 (6%) Frame = +3 Query: 2151 THEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPF-RGPGN--DETLANVVSQNLRF 2321 T ++APE++K G+ D W+ GV LY +L G TPF GP + +E L + +F Sbjct: 594 TANFVAPEVLKRQGYDEGCDIWSLGVLLYTMLAGCTPFANGPSDTPEEILTRIGGG--KF 651 Query: 2322 PDN----PVVSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPF 2441 N +S AKDL+ +L +P RL A ++ QHP+ Sbjct: 652 SVNGGNWDTISDVAKDLVSKMLHVDPHQRL----TAKQVLQHPW 691 Score = 49.3 bits (116), Expect = 9e-05 Identities = 37/113 (32%), Positives = 55/113 (48%), Gaps = 5/113 (4%) Frame = +3 Query: 1539 KVMDIEY---LISRKKMLRAQAEREILEMLDHPFLPTLYAHFTTDNLSCLVMEYCPGGDL 1709 K ++EY +I + K ++ +L HP + TL + LV E GG+L Sbjct: 455 KTTNMEYAVKVIDKSKRDPSEEIEILLRYGQHPNIITLKDVYDDGKYVYLVTELMRGGEL 514 Query: 1710 --HVLRQRQPGRSFPEPSARFYVAEVLLALEYLHMLGVIYRDLKPENILVRDD 1862 +LRQ+ F E A + + +EYLH GV++RDLKP NIL D+ Sbjct: 515 LDKILRQK----FFSEREASSVLHTICKTVEYLHSQGVVHRDLKPSNILYVDE 563
>P18654:KS6A3_MOUSE Ribosomal protein S6 kinase alpha-3 - Mus musculus (Mouse)| Length = 740 Score = 112 bits (281), Expect = 6e-24 Identities = 63/148 (42%), Positives = 95/148 (64%), Gaps = 3/148 (2%) Frame = +3 Query: 1452 FRLLKRLGCGDIGTVYLAELV---DSDCLFALKVMDIEYLISRKKMLRAQAEREILEMLD 1622 F LLK LG G G V+L + + D+ L+A+KV+ L R ++ R + ER+IL ++ Sbjct: 68 FELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATLKVRDRV-RTKMERDILVEVN 126 Query: 1623 HPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALEYL 1802 HPF+ L+ F T+ L++++ GGDL ++ F E +FY+AE+ LAL++L Sbjct: 127 HPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEV--MFTEEDVKFYLAELALALDHL 184 Query: 1803 HMLGVIYRDLKPENILVRDDGHIMLSDF 1886 H LG+IYRDLKPENIL+ ++GHI L+DF Sbjct: 185 HSLGIIYRDLKPENILLDEEGHIKLTDF 212 Score = 97.8 bits (242), Expect = 2e-19 Identities = 49/124 (39%), Positives = 72/124 (58%), Gaps = 3/124 (2%) Frame = +3 Query: 2124 EARSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVV 2303 E ++ SF GT EY+APE++ GH + DWW+FGV ++E+L G PF+G ET+ ++ Sbjct: 222 EKKAYSFCGTVEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTGTLPFQGKDRKETMTMIL 281 Query: 2304 SQNLRFPDNPVVSSNAKDLIRGLLVKEPENRLGT-LRGAAEIKQHPFFEGLNWALI--RS 2474 L P +S A+ L+R L + P NRLG G EIK+H FF ++W + R Sbjct: 282 KAKLGMPQ--FLSPEAQSLLRMLFKRNPANRLGAGPDGVEEIKRHSFFSTIDWNKLYRRE 339 Query: 2475 VAPP 2486 + PP Sbjct: 340 IHPP 343 Score = 58.2 bits (139), Expect = 2e-07 Identities = 38/102 (37%), Positives = 55/102 (53%), Gaps = 5/102 (4%) Frame = +3 Query: 2151 THEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPF-RGPGN--DETLANVVSQNLRF 2321 T ++APE++K G+ +A D W+ GV LY +L G TPF GP + +E LA + S Sbjct: 581 TANFVAPEVLKRQGYDAACDIWSLGVLLYTMLTGYTPFANGPDDTPEEILARIGSGKFSL 640 Query: 2322 PDN--PVVSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPF 2441 VS AKDL+ +L +P RL AA + +HP+ Sbjct: 641 SGGYWNSVSDTAKDLVSKMLHVDPHQRL----TAALVLRHPW 678 Score = 48.9 bits (115), Expect = 1e-04 Identities = 39/141 (27%), Positives = 63/141 (44%), Gaps = 2/141 (1%) Frame = +3 Query: 1446 DNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEMLDH 1625 D + + + +G G ++ FA+K++D + K + +L H Sbjct: 420 DGYEVKEDIGVGSYSVCKRCIHKATNMEFAVKIID------KSKRDPTEEIEILLRYGQH 473 Query: 1626 PFLPTLYAHFTTDNLSCLVMEYCPGGDL--HVLRQRQPGRSFPEPSARFYVAEVLLALEY 1799 P + TL + +V E GG+L +LRQ+ F E A + + +EY Sbjct: 474 PNIITLKDVYDDGKYVYVVTELMKGGELLDKILRQK----FFSEREASAVLFTITKTVEY 529 Query: 1800 LHMLGVIYRDLKPENILVRDD 1862 LH GV++RDLKP NIL D+ Sbjct: 530 LHAQGVVHRDLKPSNILYVDE 550
>P51812:KS6A3_HUMAN Ribosomal protein S6 kinase alpha-3 - Homo sapiens (Human)| Length = 740 Score = 112 bits (281), Expect = 6e-24 Identities = 63/148 (42%), Positives = 95/148 (64%), Gaps = 3/148 (2%) Frame = +3 Query: 1452 FRLLKRLGCGDIGTVYLAELV---DSDCLFALKVMDIEYLISRKKMLRAQAEREILEMLD 1622 F LLK LG G G V+L + + D+ L+A+KV+ L R ++ R + ER+IL ++ Sbjct: 68 FELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATLKVRDRV-RTKMERDILVEVN 126 Query: 1623 HPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALEYL 1802 HPF+ L+ F T+ L++++ GGDL ++ F E +FY+AE+ LAL++L Sbjct: 127 HPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEV--MFTEEDVKFYLAELALALDHL 184 Query: 1803 HMLGVIYRDLKPENILVRDDGHIMLSDF 1886 H LG+IYRDLKPENIL+ ++GHI L+DF Sbjct: 185 HSLGIIYRDLKPENILLDEEGHIKLTDF 212 Score = 97.8 bits (242), Expect = 2e-19 Identities = 49/124 (39%), Positives = 72/124 (58%), Gaps = 3/124 (2%) Frame = +3 Query: 2124 EARSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVV 2303 E ++ SF GT EY+APE++ GH + DWW+FGV ++E+L G PF+G ET+ ++ Sbjct: 222 EKKAYSFCGTVEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTGTLPFQGKDRKETMTMIL 281 Query: 2304 SQNLRFPDNPVVSSNAKDLIRGLLVKEPENRLGT-LRGAAEIKQHPFFEGLNWALI--RS 2474 L P +S A+ L+R L + P NRLG G EIK+H FF ++W + R Sbjct: 282 KAKLGMPQ--FLSPEAQSLLRMLFKRNPANRLGAGPDGVEEIKRHSFFSTIDWNKLYRRE 339 Query: 2475 VAPP 2486 + PP Sbjct: 340 IHPP 343 Score = 58.2 bits (139), Expect = 2e-07 Identities = 38/102 (37%), Positives = 55/102 (53%), Gaps = 5/102 (4%) Frame = +3 Query: 2151 THEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPF-RGPGN--DETLANVVSQNLRF 2321 T ++APE++K G+ +A D W+ GV LY +L G TPF GP + +E LA + S Sbjct: 581 TANFVAPEVLKRQGYDAACDIWSLGVLLYTMLTGYTPFANGPDDTPEEILARIGSGKFSL 640 Query: 2322 PDN--PVVSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPF 2441 VS AKDL+ +L +P RL AA + +HP+ Sbjct: 641 SGGYWNSVSDTAKDLVSKMLHVDPHQRL----TAALVLRHPW 678 Score = 48.9 bits (115), Expect = 1e-04 Identities = 39/141 (27%), Positives = 63/141 (44%), Gaps = 2/141 (1%) Frame = +3 Query: 1446 DNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEMLDH 1625 D + + + +G G ++ FA+K++D + K + +L H Sbjct: 420 DGYEVKEDIGVGSYSVCKRCIHKATNMEFAVKIID------KSKRDPTEEIEILLRYGQH 473 Query: 1626 PFLPTLYAHFTTDNLSCLVMEYCPGGDL--HVLRQRQPGRSFPEPSARFYVAEVLLALEY 1799 P + TL + +V E GG+L +LRQ+ F E A + + +EY Sbjct: 474 PNIITLKDVYDDGKYVYVVTELMKGGELLDKILRQK----FFSEREASAVLFTITKTVEY 529 Query: 1800 LHMLGVIYRDLKPENILVRDD 1862 LH GV++RDLKP NIL D+ Sbjct: 530 LHAQGVVHRDLKPSNILYVDE 550
>Q15349:KS6A2_HUMAN Ribosomal protein S6 kinase alpha-2 - Homo sapiens (Human)| Length = 733 Score = 112 bits (281), Expect = 6e-24 Identities = 63/148 (42%), Positives = 95/148 (64%), Gaps = 3/148 (2%) Frame = +3 Query: 1452 FRLLKRLGCGDIGTVYLAELV---DSDCLFALKVMDIEYLISRKKMLRAQAEREILEMLD 1622 F LLK LG G G V+L V D+ L+A+KV+ L R ++ R++ ER+IL ++ Sbjct: 59 FELLKVLGQGSYGKVFLVRKVKGSDAGQLYAMKVLKKATLKVRDRV-RSKMERDILAEVN 117 Query: 1623 HPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALEYL 1802 HPF+ L+ F T+ L++++ GGDL ++ F E +FY+AE+ LAL++L Sbjct: 118 HPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEV--MFTEEDVKFYLAELALALDHL 175 Query: 1803 HMLGVIYRDLKPENILVRDDGHIMLSDF 1886 H LG+IYRDLKPENIL+ ++GHI ++DF Sbjct: 176 HSLGIIYRDLKPENILLDEEGHIKITDF 203 Score = 103 bits (257), Expect = 4e-21 Identities = 52/127 (40%), Positives = 75/127 (59%), Gaps = 2/127 (1%) Frame = +3 Query: 2124 EARSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVV 2303 + R+ SF GT EY+APE++ GH + DWW+FGV ++E+L G PF+G ET+A ++ Sbjct: 213 DKRAYSFCGTIEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTGSLPFQGKDRKETMALIL 272 Query: 2304 SQNLRFPDNPVVSSNAKDLIRGLLVKEPENRLGT-LRGAAEIKQHPFFEGLNW-ALIRSV 2477 L P +S A+ L+R L + P NRLG + G EIK+HPFF ++W L R Sbjct: 273 KAKLGMPQ--FLSGEAQSLLRALFKRNPCNRLGAGIDGVEEIKRHPFFVTIDWNTLYRKE 330 Query: 2478 APPETRP 2498 P +P Sbjct: 331 IKPPFKP 337 Score = 58.9 bits (141), Expect = 1e-07 Identities = 42/141 (29%), Positives = 66/141 (46%), Gaps = 2/141 (1%) Frame = +3 Query: 1446 DNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEMLDH 1625 D + + + +G G +D +A+K++D + K ++ +L H Sbjct: 413 DGYEIKEDIGVGSYSVCKRCVHKATDTEYAVKIID------KSKRDPSEEIEILLRYGQH 466 Query: 1626 PFLPTLYAHFTTDNLSCLVMEYCPGGDL--HVLRQRQPGRSFPEPSARFYVAEVLLALEY 1799 P + TL + LVME GG+L +LRQR F E A + + ++Y Sbjct: 467 PNIITLKDVYDDGKFVYLVMELMRGGELLDRILRQRY----FSEREASDVLCTITKTMDY 522 Query: 1800 LHMLGVIYRDLKPENILVRDD 1862 LH GV++RDLKP NIL RD+ Sbjct: 523 LHSQGVVHRDLKPSNILYRDE 543 Score = 55.1 bits (131), Expect = 2e-06 Identities = 34/102 (33%), Positives = 55/102 (53%), Gaps = 5/102 (4%) Frame = +3 Query: 2151 THEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPF-RGPGN--DETLANVVSQNLRF 2321 T ++APE++K G+ +A D W+ G+ LY +L G TPF GP + +E LA + S Sbjct: 574 TANFVAPEVLKRQGYDAACDIWSLGILLYTMLAGFTPFANGPDDTPEEILARIGSGKYAL 633 Query: 2322 PDN--PVVSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPF 2441 +S AKD++ +L +P RL A ++ +HP+ Sbjct: 634 SGGNWDSISDAAKDVVSKMLHVDPHQRL----TAMQVLKHPW 671
>Q15418:KS6A1_HUMAN Ribosomal protein S6 kinase alpha-1 - Homo sapiens (Human)| Length = 735 Score = 112 bits (281), Expect = 6e-24 Identities = 64/149 (42%), Positives = 94/149 (63%), Gaps = 3/149 (2%) Frame = +3 Query: 1449 NFRLLKRLGCGDIGTVYLAELV---DSDCLFALKVMDIEYLISRKKMLRAQAEREILEML 1619 +F LLK LG G G V+L V DS L+A+KV+ L R ++ R + ER+IL + Sbjct: 61 HFELLKVLGQGSFGKVFLVRKVTRPDSGHLYAMKVLKKATLKVRDRV-RTKMERDILADV 119 Query: 1620 DHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALEY 1799 +HPF+ L+ F T+ L++++ GGDL ++ F E +FY+AE+ L L++ Sbjct: 120 NHPFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEV--MFTEEDVKFYLAELALGLDH 177 Query: 1800 LHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 LH LG+IYRDLKPENIL+ ++GHI L+DF Sbjct: 178 LHSLGIIYRDLKPENILLDEEGHIKLTDF 206 Score = 100 bits (248), Expect = 4e-20 Identities = 48/124 (38%), Positives = 75/124 (60%), Gaps = 3/124 (2%) Frame = +3 Query: 2124 EARSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVV 2303 E ++ SF GT EY+APE++ GH + DWW++GV ++E+L G PF+G ET+ ++ Sbjct: 216 EKKAYSFCGTVEYMAPEVVNRQGHSHSADWWSYGVLMFEMLTGSLPFQGKDRKETMTLIL 275 Query: 2304 SQNLRFPDNPVVSSNAKDLIRGLLVKEPENRLGT-LRGAAEIKQHPFFEGLNWALI--RS 2474 L P +S+ A+ L+R L + P NRLG+ GA EIK+H F+ ++W + R Sbjct: 276 KAKLGMPQ--FLSTEAQSLLRALFKRNPANRLGSGPDGAEEIKRHVFYSTIDWNKLYRRE 333 Query: 2475 VAPP 2486 + PP Sbjct: 334 IKPP 337 Score = 57.0 bits (136), Expect = 4e-07 Identities = 35/102 (34%), Positives = 52/102 (50%), Gaps = 5/102 (4%) Frame = +3 Query: 2151 THEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPF-RGPGN--DETLANVVSQNLRF 2321 T ++APE++K G+ D W+ G+ LY +L G TPF GP + +E L + S Sbjct: 577 TANFVAPEVLKRQGYDEGCDIWSLGILLYTMLAGYTPFANGPSDTPEEILTRIGSGKFTL 636 Query: 2322 PDN--PVVSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPF 2441 VS AKDL+ +L +P RL A ++ QHP+ Sbjct: 637 SGGNWNTVSETAKDLVSKMLHVDPHQRL----TAKQVLQHPW 674 Score = 50.4 bits (119), Expect = 4e-05 Identities = 38/113 (33%), Positives = 56/113 (49%), Gaps = 5/113 (4%) Frame = +3 Query: 1539 KVMDIEY---LISRKKMLRAQAEREILEMLDHPFLPTLYAHFTTDNLSCLVMEYCPGGDL 1709 K ++EY +I + K ++ +L HP + TL + LV E GG+L Sbjct: 438 KATNMEYAVKVIDKSKRDPSEEIEILLRYGQHPNIITLKDVYDDGKHVYLVTELMRGGEL 497 Query: 1710 --HVLRQRQPGRSFPEPSARFYVAEVLLALEYLHMLGVIYRDLKPENILVRDD 1862 +LRQ+ F E A F + + +EYLH GV++RDLKP NIL D+ Sbjct: 498 LDKILRQK----FFSEREASFVLHTIGKTVEYLHSQGVVHRDLKPSNILYVDE 546
>P24256:KAPB2_BOVIN cAMP-dependent protein kinase, beta-2-catalytic subunit - Bos taurus| (Bovine) Length = 397 Score = 112 bits (281), Expect = 6e-24 Identities = 60/149 (40%), Positives = 93/149 (62%) Frame = +3 Query: 1440 GLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEML 1619 GL++F K LG G G V L + ++ +A+K++D + ++ K++ E+ IL+ + Sbjct: 86 GLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAV 145 Query: 1620 DHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALEY 1799 + PFL L F ++ +VMEY PGG++ R+ GR F EP ARFY A+++L EY Sbjct: 146 NFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFS-HLRRIGR-FSEPHARFYAAQIVLTFEY 203 Query: 1800 LHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 LH L +IYRDLKPEN+L+ G+I ++DF Sbjct: 204 LHSLDLIYRDLKPENLLIDHQGYIQVTDF 232 Score = 87.0 bits (214), Expect = 4e-16 Identities = 50/124 (40%), Positives = 68/124 (54%), Gaps = 3/124 (2%) Frame = +3 Query: 2124 EARSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVV 2303 + R+ + GT EYLAPEII G+ AVDWW GV +YE+ G PF + +V Sbjct: 239 KGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIV 298 Query: 2304 SQNLRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLR-GAAEIKQHPFFEGLNWALI--RS 2474 S +RFP + SS+ KDL+R LL + R G L+ G ++IK H +F +W I R Sbjct: 299 SGKVRFPSH--FSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRK 356 Query: 2475 VAPP 2486 V P Sbjct: 357 VEAP 360
>P05131:KAPB1_BOVIN cAMP-dependent protein kinase, beta-1-catalytic subunit - Bos taurus| (Bovine) Length = 351 Score = 112 bits (281), Expect = 6e-24 Identities = 60/149 (40%), Positives = 93/149 (62%) Frame = +3 Query: 1440 GLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEML 1619 GL++F K LG G G V L + ++ +A+K++D + ++ K++ E+ IL+ + Sbjct: 40 GLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAV 99 Query: 1620 DHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALEY 1799 + PFL L F ++ +VMEY PGG++ R+ GR F EP ARFY A+++L EY Sbjct: 100 NFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFS-HLRRIGR-FSEPHARFYAAQIVLTFEY 157 Query: 1800 LHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 LH L +IYRDLKPEN+L+ G+I ++DF Sbjct: 158 LHSLDLIYRDLKPENLLIDHQGYIQVTDF 186 Score = 87.0 bits (214), Expect = 4e-16 Identities = 50/124 (40%), Positives = 68/124 (54%), Gaps = 3/124 (2%) Frame = +3 Query: 2124 EARSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVV 2303 + R+ + GT EYLAPEII G+ AVDWW GV +YE+ G PF + +V Sbjct: 193 KGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIV 252 Query: 2304 SQNLRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLR-GAAEIKQHPFFEGLNWALI--RS 2474 S +RFP + SS+ KDL+R LL + R G L+ G ++IK H +F +W I R Sbjct: 253 SGKVRFPSH--FSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRK 310 Query: 2475 VAPP 2486 V P Sbjct: 311 VEAP 314
>P28178:PK2_DICDI Protein kinase 2 - Dictyostelium discoideum (Slime mold)| Length = 479 Score = 112 bits (280), Expect = 8e-24 Identities = 57/147 (38%), Positives = 94/147 (63%) Frame = +3 Query: 1446 DNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEMLDH 1625 D+F LL +G G G V + D +FA+KV+ + +I+RK++ ++E+ IL+ + H Sbjct: 151 DDFELLNVIGKGSFGKVMQVKKKGEDKIFAMKVLRKDAIIARKQVNHTKSEKTILQCISH 210 Query: 1626 PFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALEYLH 1805 PF+ L+ F T + +V+++ GG+L +R+ GR F EP + Y AE++ AL++LH Sbjct: 211 PFIVNLHYAFQTKDKLYMVLDFVNGGELFFHLKRE-GR-FSEPRVKIYAAEIVSALDHLH 268 Query: 1806 MLGVIYRDLKPENILVRDDGHIMLSDF 1886 ++YRDLKPENIL+ +GHI ++DF Sbjct: 269 KQDIVYRDLKPENILLDSEGHICITDF 295 Score = 104 bits (259), Expect = 2e-21 Identities = 48/107 (44%), Positives = 67/107 (62%) Frame = +3 Query: 2139 SFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQNLR 2318 +F GT EYLAPE++ G GHG AVDWW+ G LYE+L G PF +++ L+ Sbjct: 309 TFCGTPEYLAPEVLNGHGHGCAVDWWSLGTLLYEMLTGLPPFYSQNVSTMYQKILNGELK 368 Query: 2319 FPDNPVVSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPFFEGLNW 2459 P +S AK L+ GLL +E + RLGT +G E+KQHP+F+ ++W Sbjct: 369 IP--TYISPEAKSLLEGLLTREVDKRLGT-KGGGEVKQHPWFKNIDW 412
>Q811L6:MAST4_MOUSE Microtubule-associated serine/threonine-protein kinase 4 - Mus| musculus (Mouse) Length = 2618 Score = 112 bits (280), Expect = 8e-24 Identities = 64/157 (40%), Positives = 91/157 (57%) Frame = +3 Query: 1416 LALQQGPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQA 1595 L L++ P D F +K + G G VY +S FA+K ++ + LI R ++ +A Sbjct: 557 LRLRRKPRESD-FETIKLISNGAYGAVYFVRHKESRQRFAMKKINKQNLILRNQIQQAFV 615 Query: 1596 EREILEMLDHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVA 1775 ER+IL ++PF+ ++Y F T C+VMEY GGD L + P AR Y A Sbjct: 616 ERDILTFAENPFVVSMYCSFETRRHLCMVMEYVEGGDCATLMKNMG--PLPVDMARMYFA 673 Query: 1776 EVLLALEYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 E +LALEYLH G+++RDLKP+N+LV GHI L+DF Sbjct: 674 ETVLALEYLHNYGIVHRDLKPDNLLVTSMGHIKLTDF 710 Score = 93.6 bits (231), Expect = 4e-18 Identities = 50/113 (44%), Positives = 68/113 (60%), Gaps = 2/113 (1%) Frame = +3 Query: 2148 GTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQNLRFPD 2327 GT EY+APE+I G+G VDWW G+ LYE L G PF G +E V+S + +P+ Sbjct: 743 GTPEYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDEINWPE 802 Query: 2328 -NPVVSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPFFEGLNW-ALIRSVA 2480 + +A++LI LL + P RLGT GA E+KQH FF L+W +L+R A Sbjct: 803 KDEAPPPDAQELITLLLRQNPLERLGT-GGAYEVKQHRFFRSLDWNSLLRQKA 854
>O15021:MAST4_HUMAN Microtubule-associated serine/threonine-protein kinase 4 - Homo| sapiens (Human) Length = 2444 Score = 112 bits (280), Expect = 8e-24 Identities = 64/157 (40%), Positives = 91/157 (57%) Frame = +3 Query: 1416 LALQQGPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQA 1595 L L++ P D F +K + G G VY +S FA+K ++ + LI R ++ +A Sbjct: 380 LKLRRKPRESD-FETIKLISNGAYGAVYFVRHKESRQRFAMKKINKQNLILRNQIQQAFV 438 Query: 1596 EREILEMLDHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVA 1775 ER+IL ++PF+ ++Y F T C+VMEY GGD L + P AR Y A Sbjct: 439 ERDILTFAENPFVVSMYCSFETRRHLCMVMEYVEGGDCATLMKNMG--PLPVDMARMYFA 496 Query: 1776 EVLLALEYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 E +LALEYLH G+++RDLKP+N+LV GHI L+DF Sbjct: 497 ETVLALEYLHNYGIVHRDLKPDNLLVTSMGHIKLTDF 533 Score = 95.1 bits (235), Expect = 1e-18 Identities = 51/113 (45%), Positives = 68/113 (60%), Gaps = 2/113 (1%) Frame = +3 Query: 2148 GTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQNLRFPD 2327 GT EY+APE+I G+G VDWW G+ LYE L G PF G +E V+S + +P+ Sbjct: 566 GTPEYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDEINWPE 625 Query: 2328 -NPVVSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPFFEGLNW-ALIRSVA 2480 + +A+DLI LL + P RLGT GA E+KQH FF L+W +L+R A Sbjct: 626 KDEAPPPDAQDLITLLLRQNPLERLGT-GGAYEVKQHRFFRSLDWNSLLRQKA 677
>P18653:KS6A1_MOUSE Ribosomal protein S6 kinase alpha-1 - Mus musculus (Mouse)| Length = 724 Score = 112 bits (280), Expect = 8e-24 Identities = 64/148 (43%), Positives = 93/148 (62%), Gaps = 3/148 (2%) Frame = +3 Query: 1452 FRLLKRLGCGDIGTVYLAELV---DSDCLFALKVMDIEYLISRKKMLRAQAEREILEMLD 1622 F LLK LG G G V+L V DS L+A+KV+ L R ++ R + ER+IL ++ Sbjct: 62 FELLKVLGQGSFGKVFLVRKVTRPDSGHLYAMKVLKKATLKVRDRV-RTKMERDILADVN 120 Query: 1623 HPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALEYL 1802 HPF+ L+ F T+ L++++ GGDL ++ F E +FY+AE+ L L++L Sbjct: 121 HPFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEV--MFTEEDVKFYLAELALGLDHL 178 Query: 1803 HMLGVIYRDLKPENILVRDDGHIMLSDF 1886 H LG+IYRDLKPENIL+ ++GHI L+DF Sbjct: 179 HSLGIIYRDLKPENILLDEEGHIKLTDF 206 Score = 79.0 bits (193), Expect = 1e-13 Identities = 43/124 (34%), Positives = 67/124 (54%), Gaps = 3/124 (2%) Frame = +3 Query: 2124 EARSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVV 2303 E ++ SF GT EY+APE++ GH + DWW++GV + G ET+ ++ Sbjct: 216 EKKAYSFCGTVEYMAPEVVNRQGHTHSADWWSYGVLM-----------GKDRKETMTLIL 264 Query: 2304 SQNLRFPDNPVVSSNAKDLIRGLLVKEPENRLGT-LRGAAEIKQHPFFEGLNWALI--RS 2474 L P +S+ A+ L+R L + P NRLG+ GA EIK+H F+ ++W + R Sbjct: 265 KAKLGMPQ--FLSTEAQSLLRALFKRNPANRLGSGPDGAEEIKRHIFYSTIDWNKLYRRE 322 Query: 2475 VAPP 2486 + PP Sbjct: 323 IKPP 326 Score = 57.0 bits (136), Expect = 4e-07 Identities = 35/102 (34%), Positives = 52/102 (50%), Gaps = 5/102 (4%) Frame = +3 Query: 2151 THEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPF-RGPGN--DETLANVVSQNLRF 2321 T ++APE++K G+ D W+ G+ LY +L G TPF GP + +E L + S Sbjct: 566 TANFVAPEVLKRQGYDEGCDIWSLGILLYTMLAGYTPFANGPSDTPEEILTRIGSGKFTL 625 Query: 2322 PDN--PVVSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPF 2441 VS AKDL+ +L +P RL A ++ QHP+ Sbjct: 626 SGGNWNTVSETAKDLVSKMLHVDPHQRL----TAKQVLQHPW 663 Score = 51.2 bits (121), Expect = 2e-05 Identities = 38/113 (33%), Positives = 56/113 (49%), Gaps = 5/113 (4%) Frame = +3 Query: 1539 KVMDIEY---LISRKKMLRAQAEREILEMLDHPFLPTLYAHFTTDNLSCLVMEYCPGGDL 1709 K ++EY +I + K ++ +L HP + TL + LV E GG+L Sbjct: 427 KATNMEYAVKVIDKSKRDPSEEIEILLRYGQHPNIITLKDVYDDGKHVYLVTELMRGGEL 486 Query: 1710 --HVLRQRQPGRSFPEPSARFYVAEVLLALEYLHMLGVIYRDLKPENILVRDD 1862 +LRQ+ F E A F + + +EYLH GV++RDLKP NIL D+ Sbjct: 487 LDKILRQK----FFSEREASFVLHTISKTVEYLHSQGVVHRDLKPSNILYVDE 535
>P42818:KPK1_ARATH Serine/threonine-protein kinase AtPK1/AtPK6 - Arabidopsis thaliana| (Mouse-ear cress) Length = 465 Score = 112 bits (280), Expect = 8e-24 Identities = 57/121 (47%), Positives = 78/121 (64%), Gaps = 3/121 (2%) Frame = +3 Query: 2130 RSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQ 2309 RSNS GT EY+APEI++G GH A DWW+ G+ LYE+L G+ PF G + +V Sbjct: 287 RSNSMCGTTEYMAPEIVRGKGHDKAADWWSVGILLYEMLTGKPPFLG-SKGKIQQKIVKD 345 Query: 2310 NLRFPDNPVVSSNAKDLIRGLLVKEPENRLGT-LRGAAEIKQHPFFEGLNWALI--RSVA 2480 ++ P +S+ A +++GLL KEPE RLG+ L GA EIKQH +F+G+NW + R V Sbjct: 346 KIKLPQ--FLSNEAHAILKGLLQKEPERRLGSGLSGAEEIKQHKWFKGINWKKLEAREVM 403 Query: 2481 P 2483 P Sbjct: 404 P 404 Score = 112 bits (279), Expect = 1e-23 Identities = 59/152 (38%), Positives = 93/152 (61%) Frame = +3 Query: 1431 GPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREIL 1610 G +G+D+F ++K +G G G VY ++ ++A+KVM ++++ + +AER+IL Sbjct: 127 GVVGIDDFEVMKVVGKGAFGKVYQVRKKETSEIYAMKVMRKDHIMEKNHAEYMKAERDIL 186 Query: 1611 EMLDHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLA 1790 +DHPF+ L F T LV+++ GG H+ Q F E AR Y AE++ A Sbjct: 187 TKIDHPFIVQLKYSFQTKYRLYLVLDFINGG--HLFFQLYHQGLFREDLARVYTAEIVSA 244 Query: 1791 LEYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 + +LH G+++RDLKPENIL+ DGH+ML+DF Sbjct: 245 VSHLHEKGIMHRDLKPENILMDTDGHVMLTDF 276
>Q9Y2H9:MAST1_HUMAN Microtubule-associated serine/threonine-protein kinase 1 - Homo| sapiens (Human) Length = 1570 Score = 112 bits (279), Expect = 1e-23 Identities = 61/151 (40%), Positives = 90/151 (59%) Frame = +3 Query: 1434 PLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILE 1613 P G ++F +K + G G VYL D+ FA+K ++ + LI R ++ +A ER+IL Sbjct: 368 PPGENDFDTIKLISNGAYGAVYLVRHRDTRQRFAMKKINKQNLILRNQIQQAFVERDILT 427 Query: 1614 MLDHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLAL 1793 ++PF+ ++ F T C+VMEY GGD L + + P AR Y AE +LAL Sbjct: 428 FAENPFVVGMFCSFETRRHLCMVMEYVEGGDCATLLKNIG--ALPVEMARMYFAETVLAL 485 Query: 1794 EYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 EYLH G+++RDLKP+N+L+ GHI L+DF Sbjct: 486 EYLHNYGIVHRDLKPDNLLITSMGHIKLTDF 516 Score = 90.1 bits (222), Expect = 4e-17 Identities = 49/113 (43%), Positives = 66/113 (58%), Gaps = 2/113 (1%) Frame = +3 Query: 2148 GTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQNLRFPD 2327 GT EY+APE+I G+G VDWW G+ LYE L G PF G +E V+S ++ +P+ Sbjct: 549 GTPEYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDDILWPE 608 Query: 2328 -NPVVSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPFFEGLNW-ALIRSVA 2480 + + + A+ LI LL P RLG GA E+KQH FF L+W L+R A Sbjct: 609 GDEALPTEAQLLISSLLQTNPLVRLGA-GGAFEVKQHSFFRDLDWTGLLRQKA 660
>Q9WUT3:KS6A2_MOUSE Ribosomal protein S6 kinase alpha-2 - Mus musculus (Mouse)| Length = 733 Score = 112 bits (279), Expect = 1e-23 Identities = 63/148 (42%), Positives = 95/148 (64%), Gaps = 3/148 (2%) Frame = +3 Query: 1452 FRLLKRLGCGDIGTVYLAELV---DSDCLFALKVMDIEYLISRKKMLRAQAEREILEMLD 1622 F LLK LG G G V+L V D+ L+A+KV+ L R ++ R++ ER+IL ++ Sbjct: 59 FELLKVLGQGSYGKVFLVRKVTGSDAGQLYAMKVLKKATLKVRDRV-RSKMERDILAEVN 117 Query: 1623 HPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALEYL 1802 HPF+ L+ F T+ L++++ GGDL ++ F E +FY+AE+ LAL++L Sbjct: 118 HPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEV--MFTEEDVKFYLAELALALDHL 175 Query: 1803 HMLGVIYRDLKPENILVRDDGHIMLSDF 1886 H LG+IYRDLKPENIL+ ++GHI ++DF Sbjct: 176 HGLGIIYRDLKPENILLDEEGHIKITDF 203 Score = 103 bits (256), Expect = 5e-21 Identities = 52/127 (40%), Positives = 76/127 (59%), Gaps = 2/127 (1%) Frame = +3 Query: 2124 EARSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVV 2303 + R+ SF GT EY+APE++ GH + DWW+FGV ++E+L G PF+G ET+A ++ Sbjct: 213 DKRAYSFCGTIEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTGSLPFQGKDRKETMALIL 272 Query: 2304 SQNLRFPDNPVVSSNAKDLIRGLLVKEPENRLGT-LRGAAEIKQHPFFEGLNW-ALIRSV 2477 L P +S+ A+ L+R L + P NRLG + G EIK+HPFF ++W L R Sbjct: 273 KAKLGMPQ--FLSAEAQSLLRALFKRNPCNRLGAGVDGVEEIKRHPFFVTIDWNKLYRKE 330 Query: 2478 APPETRP 2498 P +P Sbjct: 331 IKPPFKP 337 Score = 56.2 bits (134), Expect = 7e-07 Identities = 34/102 (33%), Positives = 56/102 (54%), Gaps = 5/102 (4%) Frame = +3 Query: 2151 THEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPF-RGPGN--DETLANVVSQNLRF 2321 T ++APE++K G+ +A D W+ G+ LY +L G TPF GP + +E LA + S Sbjct: 574 TANFVAPEVLKRQGYDAACDVWSLGILLYTMLAGFTPFANGPDDTPEEILARIGSGKYAL 633 Query: 2322 PDN--PVVSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPF 2441 +S AKD++ +L +P+ RL A ++ +HP+ Sbjct: 634 SGGNWDSISDAAKDVVSKMLHVDPQQRL----TAVQVLKHPW 671 Score = 55.8 bits (133), Expect = 9e-07 Identities = 41/141 (29%), Positives = 65/141 (46%), Gaps = 2/141 (1%) Frame = +3 Query: 1446 DNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEMLDH 1625 D + + + +G G +D +A+K++D + K ++ +L H Sbjct: 413 DGYEIKEDIGVGSYSVCKRCVHKATDAEYAVKIID------KSKRDPSEEIEILLRYGQH 466 Query: 1626 PFLPTLYAHFTTDNLSCLVMEYCPGGDL--HVLRQRQPGRSFPEPSARFYVAEVLLALEY 1799 P + TL + LVME GG+L +LRQR F E A + + ++Y Sbjct: 467 PNIITLKDVYDDGKYVYLVMELMRGGELLDRILRQR----CFSEREASDVLYTIARTMDY 522 Query: 1800 LHMLGVIYRDLKPENILVRDD 1862 LH GV++RDLKP NIL D+ Sbjct: 523 LHSQGVVHRDLKPSNILYMDE 543
>Q21734:KS6A1_CAEEL Putative ribosomal protein S6 kinase alpha-1 - Caenorhabditis elegans| Length = 784 Score = 112 bits (279), Expect = 1e-23 Identities = 64/148 (43%), Positives = 90/148 (60%), Gaps = 3/148 (2%) Frame = +3 Query: 1452 FRLLKRLGCGDIGTVYLAELV---DSDCLFALKVMDIEYLISRKKMLRAQAEREILEMLD 1622 F LLK LG G G V+L V DS ++A+KV+ L R + R + ER IL + Sbjct: 104 FELLKVLGQGSFGKVFLVRKVRGRDSGHVYAMKVLKKATLKVRDRQ-RTKLERNILAHIS 162 Query: 1623 HPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALEYL 1802 HPF+ L+ F T+ L++++ GGDL ++ F E +FY+AE+ LALE+L Sbjct: 163 HPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEV--MFTEDDVKFYLAELTLALEHL 220 Query: 1803 HMLGVIYRDLKPENILVRDDGHIMLSDF 1886 H LG++YRDLKPENIL+ DGHI ++DF Sbjct: 221 HSLGIVYRDLKPENILLDADGHIKVTDF 248 Score = 88.6 bits (218), Expect = 1e-16 Identities = 45/125 (36%), Positives = 73/125 (58%), Gaps = 3/125 (2%) Frame = +3 Query: 2121 TEARSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANV 2300 +E ++ SF GT EY+APE+I GH A D+W+ GV ++E+L G PF+G ++T+ + Sbjct: 257 SEKKTYSFCGTVEYMAPEVINRRGHSMAADFWSLGVLMFEMLTGHLPFQGRDRNDTMTQI 316 Query: 2301 VSQNLRFPDNPVVSSNAKDLIRGLLVKEPENRLGT-LRGAAEIKQHPFFEGLNWA--LIR 2471 + L P ++ A+ L+R L + +NRLG G EIK+H FF +++ L + Sbjct: 317 LKAKLSMPH--FLTQEAQSLLRALFKRNSQNRLGAGPDGVEEIKRHAFFAKIDFVKLLNK 374 Query: 2472 SVAPP 2486 + PP Sbjct: 375 EIDPP 379 Score = 52.0 bits (123), Expect = 1e-05 Identities = 30/88 (34%), Positives = 50/88 (56%), Gaps = 5/88 (5%) Frame = +3 Query: 2151 THEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPF-RGPGN--DETLANVVSQ--NL 2315 T +++APE+++ G+ + D W+ GV L+ +L G TPF GP + D+ L V ++ Sbjct: 614 TAQFVAPEVLRKQGYDRSCDVWSLGVLLHTMLTGCTPFAMGPNDTPDQILQRVGDGKISM 673 Query: 2316 RFPDNPVVSSNAKDLIRGLLVKEPENRL 2399 P +S AKDL+R +L +P R+ Sbjct: 674 THPVWDTISDEAKDLVRKMLDVDPNRRV 701 Score = 45.4 bits (106), Expect = 0.001 Identities = 35/138 (25%), Positives = 68/138 (49%), Gaps = 3/138 (2%) Frame = +3 Query: 1446 DNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREIL-EMLD 1622 D++ +L+++G G V+ ++ + +A+K++ +K + A E +IL Sbjct: 452 DDYEILEKIGNGAHSVVHKCQMKATRRKYAVKIV-------KKAVFDATEEVDILLRHSH 504 Query: 1623 HPFLPTLYAHFTTDNLSCLVMEYCPGGDL--HVLRQRQPGRSFPEPSARFYVAEVLLALE 1796 H F+ L+ + + ++ E C GG+L ++ ++ G E +A +L A++ Sbjct: 505 HQFVVKLFDVYEDETAIYMIEELCEGGELLDKLVNKKSLGS---EKEVAAIMANLLNAVQ 561 Query: 1797 YLHMLGVIYRDLKPENIL 1850 YLH V +RDL NIL Sbjct: 562 YLHSQQVAHRDLTAANIL 579
>O42632:KPC1_COCHE Protein kinase C-like - Cochliobolus heterostrophus (Drechslera| maydis) Length = 1174 Score = 112 bits (279), Expect = 1e-23 Identities = 65/153 (42%), Positives = 93/153 (60%), Gaps = 3/153 (1%) Frame = +3 Query: 1437 LGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEM 1616 +GLD+F L LG G+ G V LAE + L+A+KV+ E++I ++ ++E+ + + Sbjct: 844 IGLDHFNFLAVLGKGNFGKVMLAETKTTKQLYAIKVLKKEFIIENDEVESTRSEKRVFLI 903 Query: 1617 LD---HPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLL 1787 + HPFL L+A F T+ VMEY GGDL + QR F A+FY AEV L Sbjct: 904 ANKERHPFLLNLHACFQTETRVYFVMEYISGGDLMLHIQRG---QFGTKRAQFYAAEVCL 960 Query: 1788 ALEYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 AL+Y H GVIYRDLK +NI++ DGHI ++D+ Sbjct: 961 ALKYFHENGVIYRDLKLDNIMLTLDGHIKVADY 993 Score = 88.6 bits (218), Expect = 1e-16 Identities = 46/121 (38%), Positives = 73/121 (60%), Gaps = 3/121 (2%) Frame = +3 Query: 2133 SNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQN 2312 +++F GT E++APEI+ +G AVDWW FGV +Y++L ++PFRG DE +++ Sbjct: 1006 TSTFCGTPEFMAPEILLDKKYGRAVDWWAFGVLIYQMLLQQSPFRGEDEDEIYDAILADE 1065 Query: 2313 LRFPDNPVVSSNAKDLIRGLLVKEPENRLGT-LRGAAEIKQHPFFEGLNWALI--RSVAP 2483 +P + + ++ +++ LL +EPE RLG+ A EI H FF +NW I + V P Sbjct: 1066 PLYPIH--MPRDSVSILQKLLTREPEMRLGSGPTDAQEIMSHAFFRNINWDDIYHKRVQP 1123 Query: 2484 P 2486 P Sbjct: 1124 P 1124
>Q8INB9:AKT1_DROME RAC serine/threonine-protein kinase - Drosophila melanogaster (Fruit| fly) Length = 611 Score = 112 bits (279), Expect = 1e-23 Identities = 62/150 (41%), Positives = 89/150 (59%), Gaps = 2/150 (1%) Frame = +3 Query: 1443 LDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEMLD 1622 L+NF LK LG G G V L + L+A+K++ E +I + ++ E +L+ + Sbjct: 263 LENFEFLKVLGKGTFGKVILCREKATAKLYAIKILKKEVIIQKDEVAHTLTESRVLKSTN 322 Query: 1623 HPFLPTLYAHFTTDNLSCLVMEYCPGGDL--HVLRQRQPGRSFPEPSARFYVAEVLLALE 1796 HPFL +L F T++ C VM+Y GG+L H+ + R F E RFY AE++ AL Sbjct: 323 HPFLISLKYSFQTNDRLCFVMQYVNGGELFWHLSHE----RIFTEDRTRFYGAEIISALG 378 Query: 1797 YLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 YLH G+IYRDLK EN+L+ DGHI ++DF Sbjct: 379 YLHSQGIIYRDLKLENLLLDKDGHIKVADF 408 Score = 102 bits (255), Expect = 7e-21 Identities = 50/124 (40%), Positives = 76/124 (61%), Gaps = 2/124 (1%) Frame = +3 Query: 2133 SNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQN 2312 + +F GT EYLAPE++ + +G AVDWW GV +YE++ GR PF +D ++ + Sbjct: 421 TKTFCGTPEYLAPEVLDDNDYGQAVDWWGTGVVMYEMICGRLPFYNRDHDVLFTLILVEE 480 Query: 2313 LRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLR-GAAEIKQHPFFEGLNWA-LIRSVAPP 2486 ++FP N ++ AK+L+ GLL K+P+ RLG + EI+ HPFF +NW L+ PP Sbjct: 481 VKFPRN--ITDEAKNLLAGLLAKDPKKRLGGGKDDVKEIQAHPFFASINWTDLVLKKIPP 538 Query: 2487 ETRP 2498 +P Sbjct: 539 PFKP 542
>Q810W7:MAST1_RAT Microtubule-associated serine/threonine-protein kinase 1 - Rattus| norvegicus (Rat) Length = 1570 Score = 111 bits (278), Expect = 1e-23 Identities = 61/151 (40%), Positives = 89/151 (58%) Frame = +3 Query: 1434 PLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILE 1613 P G +F +K + G G VYL D+ FA+K ++ + LI R ++ +A ER+IL Sbjct: 370 PPGESDFDTIKLISNGAYGAVYLVRHRDTRQRFAMKKINKQNLILRNQIQQAFVERDILT 429 Query: 1614 MLDHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLAL 1793 ++PF+ ++ F T C+VMEY GGD L + + P AR Y AE +LAL Sbjct: 430 FAENPFVVGMFCSFETRRHLCMVMEYVEGGDCATLLKNIG--ALPVEMARMYFAETVLAL 487 Query: 1794 EYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 EYLH G+++RDLKP+N+L+ GHI L+DF Sbjct: 488 EYLHNYGIVHRDLKPDNLLITSMGHIKLTDF 518 Score = 90.5 bits (223), Expect = 3e-17 Identities = 49/113 (43%), Positives = 67/113 (59%), Gaps = 2/113 (1%) Frame = +3 Query: 2148 GTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQNLRFPD 2327 GT EY+APE+I G+G VDWW G+ LYE L G PF G +E V+S ++ +P+ Sbjct: 551 GTPEYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDDILWPE 610 Query: 2328 -NPVVSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPFFEGLNW-ALIRSVA 2480 + + ++A+ LI LL P RLG GA E+KQH FF L+W L+R A Sbjct: 611 GDEALPTDAQLLISSLLQTNPLVRLGA-GGAFEVKQHSFFRDLDWTGLLRQKA 662
>Q9R1L5:MAST1_MOUSE Microtubule-associated serine/threonine-protein kinase 1 - Mus| musculus (Mouse) Length = 1566 Score = 111 bits (278), Expect = 1e-23 Identities = 61/151 (40%), Positives = 89/151 (58%) Frame = +3 Query: 1434 PLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILE 1613 P G +F +K + G G VYL D+ FA+K ++ + LI R ++ +A ER+IL Sbjct: 369 PPGESDFDTIKLISNGAYGAVYLVRHRDTRQRFAMKKINKQNLILRNQIQQAFVERDILT 428 Query: 1614 MLDHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLAL 1793 ++PF+ ++ F T C+VMEY GGD L + + P AR Y AE +LAL Sbjct: 429 FAENPFVVGMFCSFETRRHLCMVMEYVEGGDCATLLKNIG--ALPVEMARMYFAETVLAL 486 Query: 1794 EYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 EYLH G+++RDLKP+N+L+ GHI L+DF Sbjct: 487 EYLHNYGIVHRDLKPDNLLITSMGHIKLTDF 517 Score = 90.5 bits (223), Expect = 3e-17 Identities = 49/113 (43%), Positives = 67/113 (59%), Gaps = 2/113 (1%) Frame = +3 Query: 2148 GTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQNLRFPD 2327 GT EY+APE+I G+G VDWW G+ LYE L G PF G +E V+S ++ +P+ Sbjct: 550 GTPEYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDDILWPE 609 Query: 2328 -NPVVSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPFFEGLNW-ALIRSVA 2480 + + ++A+ LI LL P RLG GA E+KQH FF L+W L+R A Sbjct: 610 GDEALPTDAQLLISSLLQTNPLVRLGA-GGAFEVKQHSFFRDLDWTGLLRQKA 661
>Q63531:KS6A1_RAT Ribosomal protein S6 kinase alpha-1 - Rattus norvegicus (Rat)| Length = 735 Score = 111 bits (278), Expect = 1e-23 Identities = 63/149 (42%), Positives = 94/149 (63%), Gaps = 3/149 (2%) Frame = +3 Query: 1449 NFRLLKRLGCGDIGTVYLAELV---DSDCLFALKVMDIEYLISRKKMLRAQAEREILEML 1619 +F LLK LG G G V+L V D+ L+A+KV+ L R ++ R + ER+IL + Sbjct: 61 HFELLKVLGQGSFGKVFLVRKVTRPDNGHLYAMKVLKKATLKVRDRV-RTKMERDILADV 119 Query: 1620 DHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALEY 1799 +HPF+ L+ F T+ L++++ GGDL ++ F E +FY+AE+ L L++ Sbjct: 120 NHPFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEV--MFTEEDVKFYLAELALGLDH 177 Query: 1800 LHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 LH LG+IYRDLKPENIL+ ++GHI L+DF Sbjct: 178 LHSLGIIYRDLKPENILLDEEGHIKLTDF 206 Score = 99.0 bits (245), Expect = 1e-19 Identities = 48/124 (38%), Positives = 75/124 (60%), Gaps = 3/124 (2%) Frame = +3 Query: 2124 EARSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVV 2303 E ++ SF GT EY+APE++ GH + DWW++GV ++E+L G PF+G ET+ ++ Sbjct: 216 EKKAYSFCGTVEYMAPEVVNRQGHTHSADWWSYGVLMFEMLTGSLPFQGKDRKETMTLIL 275 Query: 2304 SQNLRFPDNPVVSSNAKDLIRGLLVKEPENRLGT-LRGAAEIKQHPFFEGLNWALI--RS 2474 L P +S+ A+ L+R L + P NRLG+ GA EIK+H F+ ++W + R Sbjct: 276 KAKLGMPQ--FLSTEAQSLLRALFKRNPANRLGSGPDGAEEIKRHIFYSTIDWNKLYRRE 333 Query: 2475 VAPP 2486 + PP Sbjct: 334 IKPP 337 Score = 57.8 bits (138), Expect = 2e-07 Identities = 36/102 (35%), Positives = 52/102 (50%), Gaps = 5/102 (4%) Frame = +3 Query: 2151 THEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPF-RGPGN--DETLANVVSQNLRF 2321 T ++APE++K G+ D W+ GV LY +L G TPF GP + +E L + S Sbjct: 577 TANFVAPEVLKRQGYDEGCDIWSLGVLLYTMLAGYTPFANGPSDTPEEILTRISSGKFTL 636 Query: 2322 PDN--PVVSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPF 2441 VS AKDL+ +L +P RL A ++ QHP+ Sbjct: 637 SGGNWNTVSETAKDLVSKMLHVDPHQRL----TAKQVLQHPW 674 Score = 51.6 bits (122), Expect = 2e-05 Identities = 38/113 (33%), Positives = 56/113 (49%), Gaps = 5/113 (4%) Frame = +3 Query: 1539 KVMDIEY---LISRKKMLRAQAEREILEMLDHPFLPTLYAHFTTDNLSCLVMEYCPGGDL 1709 K ++EY +I + K ++ +L HP + TL + LV E GG+L Sbjct: 438 KATNMEYAVKVIDKSKRDPSEEIEILLRYGQHPNIITLKDVYDDSKHVYLVTELMRGGEL 497 Query: 1710 --HVLRQRQPGRSFPEPSARFYVAEVLLALEYLHMLGVIYRDLKPENILVRDD 1862 +LRQ+ F E A F + + +EYLH GV++RDLKP NIL D+ Sbjct: 498 LDKILRQK----FFSEREASFVLYTISKTVEYLHSQGVVHRDLKPSNILYVDE 546
>Q90XF2:KPCI_DANRE Protein kinase C iota type - Danio rerio (Zebrafish) (Brachydanio| rerio) Length = 588 Score = 111 bits (278), Expect = 1e-23 Identities = 64/151 (42%), Positives = 92/151 (60%), Gaps = 1/151 (0%) Frame = +3 Query: 1437 LGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEM 1616 LGL +F LL+ +G G V L L ++ ++A+KV+ E + + + Q E+ + E Sbjct: 241 LGLIDFDLLRVIGRGSYAKVLLVRLKKTERIYAMKVVKKELVNDDEDIDWVQTEKHVFEQ 300 Query: 1617 L-DHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLAL 1793 +HPFL L++ F T++ V+EY GGDL QRQ R PE ARFY AE+ LAL Sbjct: 301 ASNHPFLVGLHSCFQTESRLFFVIEYVNGGDLMFHMQRQ--RKLPEEHARFYSAEISLAL 358 Query: 1794 EYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 YLH G+IYRDLK +N+L+ +GHI L+D+ Sbjct: 359 NYLHERGIIYRDLKLDNVLLDSEGHIKLTDY 389 Score = 87.0 bits (214), Expect = 4e-16 Identities = 46/131 (35%), Positives = 76/131 (58%), Gaps = 13/131 (9%) Frame = +3 Query: 2133 SNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGN---------DE 2285 +++F GT Y+APEI++G+ +G +VDWW GV ++E++ GR+PF G+ D Sbjct: 402 TSTFCGTPNYIAPEILRGEDYGFSVDWWALGVLMFEMMAGRSPFDIVGSSDNPDQNTEDY 461 Query: 2286 TLANVVSQNLRFPDNPVVSSNAKDLIRGLLVKEPENRLG--TLRGAAEIKQHPFFEGLNW 2459 ++ + +R P + +S A +++G L KE + RLG G A+I HPFF ++W Sbjct: 462 LFQVILEKQIRIPRS--LSVKAASVLKGFLNKESKERLGCHPQTGFADIMAHPFFRNVDW 519 Query: 2460 ALI--RSVAPP 2486 L+ + V PP Sbjct: 520 DLMEQKQVVPP 530
>Q17941:AKT1_CAEEL Serine/threonine-protein kinase akt-1 - Caenorhabditis elegans| Length = 541 Score = 111 bits (278), Expect = 1e-23 Identities = 59/156 (37%), Positives = 94/156 (60%) Frame = +3 Query: 1419 ALQQGPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAE 1598 A ++ + +++F LK LG G G V L + + L+A+K++ + +I+R+++ E Sbjct: 182 AAKRDKITMEDFDFLKVLGKGTFGKVILCKEKRTQKLYAIKILKKDVIIAREEVAHTLTE 241 Query: 1599 REILEMLDHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAE 1778 +L+ HPFL L F + C VM++ GG+L R+ G +F EP ARFY AE Sbjct: 242 NRVLQRCKHPFLTELKYSFQEQHYLCFVMQFANGGELFT-HVRKCG-TFSEPRARFYGAE 299 Query: 1779 VLLALEYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 ++LAL YLH ++YRD+K EN+L+ DGHI ++DF Sbjct: 300 IVLALGYLHRCDIVYRDMKLENLLLDKDGHIKIADF 335 Score = 89.4 bits (220), Expect = 8e-17 Identities = 48/125 (38%), Positives = 73/125 (58%), Gaps = 2/125 (1%) Frame = +3 Query: 2130 RSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQ 2309 ++++F GT EYLAPE++ +G VDWW GV +YE++ GR PF +++ +++ Sbjct: 347 KTSTFCGTPEYLAPEVLDDHDYGRCVDWWGVGVVMYEMMCGRLPFYSKDHNKLFELIMAG 406 Query: 2310 NLRFPDNPVVSSNAKDLIRGLLVKEPENRL-GTLRGAAEIKQHPFFEGLNW-ALIRSVAP 2483 +LRFP +S A+ L+ GLLVK+P RL G A EI + FF ++W A R Sbjct: 407 DLRFPSK--LSQEARTLLTGLLVKDPTQRLGGGPEDALEICRADFFRTVDWEATYRKEIE 464 Query: 2484 PETRP 2498 P +P Sbjct: 465 PPYKP 469
>Q5R7A7:SGK3_PONPY Serine/threonine-protein kinase Sgk3 - Pongo pygmaeus (Orangutan)| Length = 496 Score = 111 bits (277), Expect = 2e-23 Identities = 62/147 (42%), Positives = 90/147 (61%), Gaps = 1/147 (0%) Frame = +3 Query: 1449 NFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREIL-EMLDH 1625 +F LK +G G G V LA+ +A+KV+ + +++RK+ AER +L + + H Sbjct: 161 DFDFLKVIGKGSFGKVLLAKRKLDGKFYAVKVLQKKIVLNRKEQKHIMAERNVLLKNVKH 220 Query: 1626 PFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALEYLH 1805 PFL L+ F T V+++ GG+L QR+ RSFPE ARFY AE+ AL YLH Sbjct: 221 PFLVGLHYSFQTTEKLYFVLDFVNGGELFFHLQRE--RSFPEHRARFYAAEIASALGYLH 278 Query: 1806 MLGVIYRDLKPENILVRDDGHIMLSDF 1886 + ++YRDLKPENIL+ GH++L+DF Sbjct: 279 SIKIVYRDLKPENILLDSVGHVVLTDF 305 Score = 95.5 bits (236), Expect = 1e-18 Identities = 51/123 (41%), Positives = 69/123 (56%), Gaps = 1/123 (0%) Frame = +3 Query: 2133 SNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQN 2312 + +F GT EYLAPE+I+ + + VDWW G LYE+LYG PF E N++ + Sbjct: 318 TTTFCGTPEYLAPEVIRKQPYDNTVDWWCLGAVLYEMLYGLPPFYCRDVAEMYDNILHKP 377 Query: 2313 LRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPFFEGLNWA-LIRSVAPPE 2489 L P VS A ++ LL K+ +NRLG EI+ HPFFE L+WA L++ PP Sbjct: 378 LSL--RPGVSLTAWSILEELLEKDRQNRLGAKEDFLEIQNHPFFESLSWADLVQKKIPPP 435 Query: 2490 TRP 2498 P Sbjct: 436 FNP 438
>Q96BR1:SGK3_HUMAN Serine/threonine-protein kinase Sgk3 - Homo sapiens (Human)| Length = 496 Score = 111 bits (277), Expect = 2e-23 Identities = 62/147 (42%), Positives = 90/147 (61%), Gaps = 1/147 (0%) Frame = +3 Query: 1449 NFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREIL-EMLDH 1625 +F LK +G G G V LA+ +A+KV+ + +++RK+ AER +L + + H Sbjct: 161 DFDFLKVIGKGSFGKVLLAKRKLDGKFYAVKVLQKKIVLNRKEQKHIMAERNVLLKNVKH 220 Query: 1626 PFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALEYLH 1805 PFL L+ F T V+++ GG+L QR+ RSFPE ARFY AE+ AL YLH Sbjct: 221 PFLVGLHYSFQTTEKLYFVLDFVNGGELFFHLQRE--RSFPEHRARFYAAEIASALGYLH 278 Query: 1806 MLGVIYRDLKPENILVRDDGHIMLSDF 1886 + ++YRDLKPENIL+ GH++L+DF Sbjct: 279 SIKIVYRDLKPENILLDSVGHVVLTDF 305 Score = 95.5 bits (236), Expect = 1e-18 Identities = 51/123 (41%), Positives = 69/123 (56%), Gaps = 1/123 (0%) Frame = +3 Query: 2133 SNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQN 2312 + +F GT EYLAPE+I+ + + VDWW G LYE+LYG PF E N++ + Sbjct: 318 TTTFCGTPEYLAPEVIRKQPYDNTVDWWCLGAVLYEMLYGLPPFYCRDVAEMYDNILHKP 377 Query: 2313 LRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPFFEGLNWA-LIRSVAPPE 2489 L P VS A ++ LL K+ +NRLG EI+ HPFFE L+WA L++ PP Sbjct: 378 LSL--RPGVSLTAWSILEELLEKDRQNRLGAKEDFLEIQNHPFFESLSWADLVQKKIPPP 435 Query: 2490 TRP 2498 P Sbjct: 436 FNP 438
>Q9HBY8:SGK2_HUMAN Serine/threonine-protein kinase Sgk2 - Homo sapiens (Human)| Length = 427 Score = 111 bits (277), Expect = 2e-23 Identities = 63/147 (42%), Positives = 88/147 (59%), Gaps = 1/147 (0%) Frame = +3 Query: 1449 NFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREIL-EMLDH 1625 +F LK +G G+ G V LA+ +A+KV+ + ++ +K+ AER +L + + H Sbjct: 94 DFDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKKKEQSHIMAERSVLLKNVRH 153 Query: 1626 PFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALEYLH 1805 PFL L F T V++Y GG+L QR+ R F EP ARFY AEV A+ YLH Sbjct: 154 PFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRE--RRFLEPRARFYAAEVASAIGYLH 211 Query: 1806 MLGVIYRDLKPENILVRDDGHIMLSDF 1886 L +IYRDLKPENIL+ GH++L+DF Sbjct: 212 SLNIIYRDLKPENILLDCQGHVVLTDF 238 Score = 92.4 bits (228), Expect = 9e-18 Identities = 48/116 (41%), Positives = 67/116 (57%) Frame = +3 Query: 2112 VEPTEARSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETL 2291 VEP + S +F GT EYLAPE+++ + + AVDWW G LYE+L+G PF + Sbjct: 245 VEPEDTTS-TFCGTPEYLAPEVLRKEPYDRAVDWWCLGAVLYEMLHGLPPFYSQDVSQMY 303 Query: 2292 ANVVSQNLRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPFFEGLNW 2459 N++ Q L+ P V+ A DL++ LL K+ RLG+ EIK H FF +NW Sbjct: 304 ENILHQPLQIPGGRTVA--ACDLLQSLLHKDQRQRLGSKADFLEIKNHVFFSPINW 357
>Q5R4K3:KS6A5_PONPY Ribosomal protein S6 kinase alpha-5 - Pongo pygmaeus (Orangutan)| Length = 802 Score = 111 bits (277), Expect = 2e-23 Identities = 65/156 (41%), Positives = 97/156 (62%), Gaps = 6/156 (3%) Frame = +3 Query: 1437 LGLDNFRLLKRLGCGDIGTVYLAELV---DSDCLFALKVMDIEYLISRKKMLR-AQAERE 1604 +G++NF LLK LG G G V+L + D+ L+A+KV+ ++ + K + ER+ Sbjct: 44 VGIENFELLKVLGTGAYGKVFLVRKISGHDTGKLYAMKVLKKATIVQKAKTTEHTRTERQ 103 Query: 1605 ILEML-DHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHV-LRQRQPGRSFPEPSARFYVAE 1778 +LE PFL TL+ F T+ L+++Y GG+L L QR+ F E + YV E Sbjct: 104 VLEHTRQSPFLVTLHYAFQTETKLHLILDYINGGELFTHLSQRE---RFTEHEVQIYVGE 160 Query: 1779 VLLALEYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 ++LALE+LH LG+IYRD+K ENIL+ +GH+ML+DF Sbjct: 161 IVLALEHLHKLGIIYRDIKLENILLDSNGHVMLTDF 196 Score = 101 bits (251), Expect = 2e-20 Identities = 57/124 (45%), Positives = 80/124 (64%), Gaps = 5/124 (4%) Frame = +3 Query: 2103 QLVVEPTEARSNSFVGTHEYLAPEIIKG--DGHGSAVDWWTFGVFLYELLYGRTPFRGPG 2276 + V + TE R+ SF GT EY+AP+I++G GH AVDWW+ GV +YELL G +PF G Sbjct: 201 EFVADETE-RAYSFCGTIEYMAPDIVRGGDSGHDKAVDWWSLGVLMYELLTGASPFTVDG 259 Query: 2277 NDETLANVVSQNLRF--PDNPVVSSNAKDLIRGLLVKEPENRLGT-LRGAAEIKQHPFFE 2447 + A + + L+ P +S+ AKDLI+ LL+K+P+ RLG R A EIK+H FF+ Sbjct: 260 EKNSQAEISRRILKSEPPYPQEMSALAKDLIQHLLMKDPKKRLGCGPRDADEIKEHLFFQ 319 Query: 2448 GLNW 2459 +NW Sbjct: 320 KINW 323 Score = 58.2 bits (139), Expect = 2e-07 Identities = 49/176 (27%), Positives = 86/176 (48%), Gaps = 4/176 (2%) Frame = +3 Query: 1371 RPHMVKDLCWITIRQLALQQGPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMD 1550 R M+KD + L L+ PLG +F + ++ S+ FA+K+ Sbjct: 410 RSAMMKDSPFYQHYDLDLKDKPLGEGSFSICRK-----------CVHKKSNQAFAVKI-- 456 Query: 1551 IEYLISRKKMLRAQAEREILEMLD-HPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQR 1727 IS++ Q E L++ + HP + L+ F + LVME GG+L ++ Sbjct: 457 ----ISKRMEANTQKEITALKLCEGHPNIVKLHEVFHDQLHTFLVMELLNGGELFERIKK 512 Query: 1728 QPGRSFPEPSARFYVAEVLLALEYLHMLGVIYRDLKPENILVRDDG---HIMLSDF 1886 + + F E A + + +++ A+ ++H +GV++RDLKPEN+L D+ I + DF Sbjct: 513 K--KHFSETEASYIMRKLVSAVSHMHDVGVVHRDLKPENLLFTDENDNLEIKIIDF 566 Score = 55.1 bits (131), Expect = 2e-06 Identities = 31/92 (33%), Positives = 44/92 (47%), Gaps = 9/92 (9%) Frame = +3 Query: 2151 THEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQNLRFPDN 2330 T Y APE++ +G+ + D W+ GV LY +L G+ PF+ T + V + Sbjct: 585 TLHYAAPELLNQNGYDESCDLWSLGVILYTMLSGQVPFQSHDRSLTCTSAVEIMKKIKKG 644 Query: 2331 PV---------VSSNAKDLIRGLLVKEPENRL 2399 VS AKDLI+GLL +P RL Sbjct: 645 DFSFEGEAWKNVSQEAKDLIQGLLTVDPNKRL 676
>Q39030:KPK19_ARATH Serine/threonine-protein kinase AtPK19 - Arabidopsis thaliana| (Mouse-ear cress) Length = 471 Score = 111 bits (277), Expect = 2e-23 Identities = 60/152 (39%), Positives = 92/152 (60%) Frame = +3 Query: 1431 GPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREIL 1610 G +G+++F +LK +G G G VY D+ ++A+KVM + ++ + +AER+IL Sbjct: 133 GVVGIEDFEVLKVVGQGAFGKVYQVRKKDTSEIYAMKVMRKDKIVEKNHAEYMKAERDIL 192 Query: 1611 EMLDHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLA 1790 +DHPF+ L F T LV+++ GG H+ Q F E AR Y AE++ A Sbjct: 193 TKIDHPFIVQLKYSFQTKYRLYLVLDFINGG--HLFFQLYHQGLFREDLARVYTAEIVSA 250 Query: 1791 LEYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 + +LH G+++RDLKPENIL+ DGH+ML+DF Sbjct: 251 VSHLHEKGIMHRDLKPENILMDVDGHVMLTDF 282 Score = 106 bits (265), Expect = 5e-22 Identities = 55/121 (45%), Positives = 76/121 (62%), Gaps = 3/121 (2%) Frame = +3 Query: 2130 RSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQ 2309 RSNS GT EY+APEI++G GH A DWW+ G+ LYE+L G+ PF G + +V Sbjct: 293 RSNSMCGTTEYMAPEIVRGKGHDKAADWWSVGILLYEMLTGKPPFLG-SKGKIQQKIVKD 351 Query: 2310 NLRFPDNPVVSSNAKDLIRGLLVKEPENRLGT-LRGAAEIKQHPFFEGLNWALI--RSVA 2480 ++ P +S+ A L++GLL KEPE RLG+ GA EIK+H +F+ +NW + R V Sbjct: 352 KIKLPQ--FLSNEAHALLKGLLQKEPERRLGSGPSGAEEIKKHKWFKAINWKKLEAREVQ 409 Query: 2481 P 2483 P Sbjct: 410 P 410
>P09217:KPCZ_RAT Protein kinase C zeta type - Rattus norvegicus (Rat)| Length = 592 Score = 111 bits (277), Expect = 2e-23 Identities = 65/158 (41%), Positives = 95/158 (60%), Gaps = 1/158 (0%) Frame = +3 Query: 1416 LALQQGPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQA 1595 + + QG LGL +F L++ +G G V L L +D ++A+KV+ E + + + Q Sbjct: 241 IKISQG-LGLQDFDLIRVIGRGSYAKVLLVRLKKNDQIYAMKVVKKELVHDDEDIDWVQT 299 Query: 1596 EREILEMLD-HPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYV 1772 E+ + E +PFL L++ F T + LV+EY GGDL QRQ R PE ARFY Sbjct: 300 EKHVFEQASSNPFLVGLHSCFQTTSRLFLVIEYVNGGDLMFHMQRQ--RKLPEEHARFYA 357 Query: 1773 AEVLLALEYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 AE+ +AL +LH G+IYRDLK +N+L+ DGHI L+D+ Sbjct: 358 AEICIALNFLHERGIIYRDLKLDNVLLDADGHIKLTDY 395 Score = 82.8 bits (203), Expect = 7e-15 Identities = 44/129 (34%), Positives = 74/129 (57%), Gaps = 11/129 (8%) Frame = +3 Query: 2133 SNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPF----RGPG---NDETL 2291 +++F GT Y+APEI++G+ +G +VDWW GV ++E++ GR+PF P D Sbjct: 408 TSTFCGTPNYIAPEILRGEEYGFSVDWWALGVLMFEMMAGRSPFDIITDNPDMNTEDYLF 467 Query: 2292 ANVVSQNLRFPDNPVVSSNAKDLIRGLLVKEPENRLG--TLRGAAEIKQHPFFEGLNWAL 2465 ++ + +R P +S A +++G L K+P+ RLG G ++IK H FF ++W L Sbjct: 468 QVILEKPIRIP--RFLSVKASHVLKGFLNKDPKERLGCRPQTGFSDIKSHAFFRSIDWDL 525 Query: 2466 I--RSVAPP 2486 + + PP Sbjct: 526 LEKKQTLPP 534
>Q02956:KPCZ_MOUSE Protein kinase C zeta type - Mus musculus (Mouse)| Length = 592 Score = 111 bits (277), Expect = 2e-23 Identities = 65/158 (41%), Positives = 95/158 (60%), Gaps = 1/158 (0%) Frame = +3 Query: 1416 LALQQGPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQA 1595 + + QG LGL +F L++ +G G V L L +D ++A+KV+ E + + + Q Sbjct: 241 IKISQG-LGLQDFDLIRVIGRGSYAKVLLVRLKKNDQIYAMKVVKKELVHDDEDIDWVQT 299 Query: 1596 EREILEMLD-HPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYV 1772 E+ + E +PFL L++ F T + LV+EY GGDL QRQ R PE ARFY Sbjct: 300 EKHVFEQASSNPFLVGLHSCFQTTSRLFLVIEYVNGGDLMFHMQRQ--RKLPEEHARFYA 357 Query: 1773 AEVLLALEYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 AE+ +AL +LH G+IYRDLK +N+L+ DGHI L+D+ Sbjct: 358 AEICIALNFLHERGIIYRDLKLDNVLLDADGHIKLTDY 395 Score = 82.8 bits (203), Expect = 7e-15 Identities = 44/129 (34%), Positives = 74/129 (57%), Gaps = 11/129 (8%) Frame = +3 Query: 2133 SNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPF----RGPG---NDETL 2291 +++F GT Y+APEI++G+ +G +VDWW GV ++E++ GR+PF P D Sbjct: 408 TSTFCGTPNYIAPEILRGEEYGFSVDWWALGVLMFEMMAGRSPFDIITDNPDMNTEDYLF 467 Query: 2292 ANVVSQNLRFPDNPVVSSNAKDLIRGLLVKEPENRLG--TLRGAAEIKQHPFFEGLNWAL 2465 ++ + +R P +S A +++G L K+P+ RLG G ++IK H FF ++W L Sbjct: 468 QVILEKPIRIP--RFLSVKASHVLKGFLNKDPKERLGCRPQTGFSDIKSHAFFRSIDWDL 525 Query: 2466 I--RSVAPP 2486 + + PP Sbjct: 526 LEKKQTLPP 534
>Q05513:KPCZ_HUMAN Protein kinase C zeta type - Homo sapiens (Human)| Length = 592 Score = 111 bits (277), Expect = 2e-23 Identities = 65/158 (41%), Positives = 95/158 (60%), Gaps = 1/158 (0%) Frame = +3 Query: 1416 LALQQGPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQA 1595 + + QG LGL +F L++ +G G V L L +D ++A+KV+ E + + + Q Sbjct: 241 IKISQG-LGLQDFDLIRVIGRGSYAKVLLVRLKKNDQIYAMKVVKKELVHDDEDIDWVQT 299 Query: 1596 EREILEMLD-HPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYV 1772 E+ + E +PFL L++ F T + LV+EY GGDL QRQ R PE ARFY Sbjct: 300 EKHVFEQASSNPFLVGLHSCFQTTSRLFLVIEYVNGGDLMFHMQRQ--RKLPEEHARFYA 357 Query: 1773 AEVLLALEYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 AE+ +AL +LH G+IYRDLK +N+L+ DGHI L+D+ Sbjct: 358 AEICIALNFLHERGIIYRDLKLDNVLLDADGHIKLTDY 395 Score = 82.8 bits (203), Expect = 7e-15 Identities = 44/129 (34%), Positives = 74/129 (57%), Gaps = 11/129 (8%) Frame = +3 Query: 2133 SNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPF----RGPG---NDETL 2291 +++F GT Y+APEI++G+ +G +VDWW GV ++E++ GR+PF P D Sbjct: 408 TSTFCGTPNYIAPEILRGEEYGFSVDWWALGVLMFEMMAGRSPFDIITDNPDMNTEDYLF 467 Query: 2292 ANVVSQNLRFPDNPVVSSNAKDLIRGLLVKEPENRLG--TLRGAAEIKQHPFFEGLNWAL 2465 ++ + +R P +S A +++G L K+P+ RLG G ++IK H FF ++W L Sbjct: 468 QVILEKPIRIP--RFLSVKASHVLKGFLNKDPKERLGCRPQTGFSDIKSHAFFRSIDWDL 525 Query: 2466 I--RSVAPP 2486 + + PP Sbjct: 526 LEKKQALPP 534
>P05132:KAPCA_MOUSE cAMP-dependent protein kinase, alpha-catalytic subunit - Mus musculus| (Mouse) Length = 351 Score = 111 bits (277), Expect = 2e-23 Identities = 61/153 (39%), Positives = 92/153 (60%) Frame = +3 Query: 1428 QGPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREI 1607 Q LD F +K LG G G V L + +S +A+K++D + ++ K++ E+ I Sbjct: 36 QNTAQLDQFDRIKTLGTGSFGRVMLVKHKESGNHYAMKILDKQKVVKLKQIEHTLNEKRI 95 Query: 1608 LEMLDHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLL 1787 L+ ++ PFL L F ++ +VMEY GG++ R+ GR F EP ARFY A+++L Sbjct: 96 LQAVNFPFLVKLEFSFKDNSNLYMVMEYVAGGEMFS-HLRRIGR-FSEPHARFYAAQIVL 153 Query: 1788 ALEYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 EYLH L +IYRDLKPEN+L+ G+I ++DF Sbjct: 154 TFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDF 186 Score = 86.3 bits (212), Expect = 6e-16 Identities = 50/124 (40%), Positives = 67/124 (54%), Gaps = 3/124 (2%) Frame = +3 Query: 2124 EARSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVV 2303 + R+ + GT EYLAPEII G+ AVDWW GV +YE+ G PF + +V Sbjct: 193 KGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIV 252 Query: 2304 SQNLRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLR-GAAEIKQHPFFEGLNWALI--RS 2474 S +RFP + SS+ KDL+R LL + R G L+ G +IK H +F +W I R Sbjct: 253 SGKVRFPSH--FSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRK 310 Query: 2475 VAPP 2486 V P Sbjct: 311 VEAP 314
>Q8C050:KS6A5_MOUSE Ribosomal protein S6 kinase alpha-5 - Mus musculus (Mouse)| Length = 863 Score = 110 bits (276), Expect = 2e-23 Identities = 64/156 (41%), Positives = 98/156 (62%), Gaps = 6/156 (3%) Frame = +3 Query: 1437 LGLDNFRLLKRLGCGDIGTVYLAELV---DSDCLFALKVMDIEYLISRKKMLR-AQAERE 1604 +G++NF LLK LG G G V+L + D+ L+A+KV+ ++ + K + ER+ Sbjct: 43 VGIENFELLKVLGTGAYGKVFLVRKISGHDAGKLYAMKVLKKATIVQKAKTTEHTRTERQ 102 Query: 1605 ILEML-DHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHV-LRQRQPGRSFPEPSARFYVAE 1778 +LE + PFL TL+ F T+ L+++Y GG+L L QR+ F E + YV E Sbjct: 103 VLEHIRQSPFLVTLHYAFQTETKLHLILDYINGGELFTHLSQRE---RFTEHEVQIYVGE 159 Query: 1779 VLLALEYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 ++LALE+LH LG+IYRD+K ENIL+ +GH++L+DF Sbjct: 160 IVLALEHLHKLGIIYRDIKLENILLDSNGHVVLTDF 195 Score = 99.8 bits (247), Expect = 6e-20 Identities = 56/124 (45%), Positives = 79/124 (63%), Gaps = 5/124 (4%) Frame = +3 Query: 2103 QLVVEPTEARSNSFVGTHEYLAPEIIKG--DGHGSAVDWWTFGVFLYELLYGRTPFRGPG 2276 + V + TE R+ SF GT EY+AP+I++G GH AVDWW+ GV +YELL G +PF G Sbjct: 200 EFVADETE-RAYSFCGTIEYMAPDIVRGGDSGHDKAVDWWSLGVLMYELLTGASPFTVDG 258 Query: 2277 NDETLANVVSQNLRF--PDNPVVSSNAKDLIRGLLVKEPENRLGT-LRGAAEIKQHPFFE 2447 + A + + L+ P +S+ AKDL++ LL+K+P+ RLG R A EIK+H FFE Sbjct: 259 EKNSQAEISRRILKSEPPYPQEMSTVAKDLLQRLLMKDPKKRLGCGPRDAEEIKEHLFFE 318 Query: 2448 GLNW 2459 + W Sbjct: 319 KIKW 322 Score = 54.7 bits (130), Expect = 2e-06 Identities = 31/92 (33%), Positives = 44/92 (47%), Gaps = 9/92 (9%) Frame = +3 Query: 2151 THEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQNLRFPDN 2330 T Y APE++ +G+ + D W+ GV LY +L G+ PF+ T + V + Sbjct: 649 TLHYAAPELLTHNGYDESCDLWSLGVILYTMLSGQVPFQSHDRSLTCTSAVEIMKKIKKG 708 Query: 2331 PV---------VSSNAKDLIRGLLVKEPENRL 2399 VS AKDLI+GLL +P RL Sbjct: 709 DFSFEGEAWKNVSQEAKDLIQGLLTVDPNKRL 740 Score = 48.5 bits (114), Expect = 1e-04 Identities = 24/62 (38%), Positives = 41/62 (66%) Frame = +3 Query: 1677 LVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALEYLHMLGVIYRDLKPENILVR 1856 LVME GG+L +R+ + F E A + + +++ A+ ++H +GV++RDLKPEN+L Sbjct: 560 LVMELLNGGELFERIKRK--KHFSETEASYIMRKLVSAVSHMHDVGVVHRDLKPENLLFT 617 Query: 1857 DD 1862 D+ Sbjct: 618 DE 619
>O75582:KS6A5_HUMAN Ribosomal protein S6 kinase alpha-5 - Homo sapiens (Human)| Length = 802 Score = 110 bits (276), Expect = 2e-23 Identities = 64/156 (41%), Positives = 98/156 (62%), Gaps = 6/156 (3%) Frame = +3 Query: 1437 LGLDNFRLLKRLGCGDIGTVYLAELV---DSDCLFALKVMDIEYLISRKKMLR-AQAERE 1604 +G++NF LLK LG G G V+L + D+ L+A+KV+ ++ + K + ER+ Sbjct: 44 VGIENFELLKVLGTGAYGKVFLVRKISGHDTGKLYAMKVLKKATIVQKAKTTEHTRTERQ 103 Query: 1605 ILEML-DHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHV-LRQRQPGRSFPEPSARFYVAE 1778 +LE + PFL TL+ F T+ L+++Y GG+L L QR+ F E + YV E Sbjct: 104 VLEHIRQSPFLVTLHYAFQTETKLHLILDYINGGELFTHLSQRE---RFTEHEVQIYVGE 160 Query: 1779 VLLALEYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 ++LALE+LH LG+IYRD+K ENIL+ +GH++L+DF Sbjct: 161 IVLALEHLHKLGIIYRDIKLENILLDSNGHVVLTDF 196 Score = 101 bits (251), Expect = 2e-20 Identities = 57/124 (45%), Positives = 80/124 (64%), Gaps = 5/124 (4%) Frame = +3 Query: 2103 QLVVEPTEARSNSFVGTHEYLAPEIIKG--DGHGSAVDWWTFGVFLYELLYGRTPFRGPG 2276 + V + TE R+ SF GT EY+AP+I++G GH AVDWW+ GV +YELL G +PF G Sbjct: 201 EFVADETE-RAYSFCGTIEYMAPDIVRGGDSGHDKAVDWWSLGVLMYELLTGASPFTVDG 259 Query: 2277 NDETLANVVSQNLRF--PDNPVVSSNAKDLIRGLLVKEPENRLGT-LRGAAEIKQHPFFE 2447 + A + + L+ P +S+ AKDLI+ LL+K+P+ RLG R A EIK+H FF+ Sbjct: 260 EKNSQAEISRRILKSEPPYPQEMSALAKDLIQRLLMKDPKKRLGCGPRDADEIKEHLFFQ 319 Query: 2448 GLNW 2459 +NW Sbjct: 320 KINW 323 Score = 58.2 bits (139), Expect = 2e-07 Identities = 49/176 (27%), Positives = 86/176 (48%), Gaps = 4/176 (2%) Frame = +3 Query: 1371 RPHMVKDLCWITIRQLALQQGPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMD 1550 R M+KD + L L+ PLG +F + ++ S+ FA+K+ Sbjct: 410 RSAMMKDSPFYQHYDLDLKDKPLGEGSFSICRK-----------CVHKKSNQAFAVKI-- 456 Query: 1551 IEYLISRKKMLRAQAEREILEMLD-HPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQR 1727 IS++ Q E L++ + HP + L+ F + LVME GG+L ++ Sbjct: 457 ----ISKRMEANTQKEITALKLCEGHPNIVKLHEVFHDQLHTFLVMELLNGGELFERIKK 512 Query: 1728 QPGRSFPEPSARFYVAEVLLALEYLHMLGVIYRDLKPENILVRDDG---HIMLSDF 1886 + + F E A + + +++ A+ ++H +GV++RDLKPEN+L D+ I + DF Sbjct: 513 K--KHFSETEASYIMRKLVSAVSHMHDVGVVHRDLKPENLLFTDENDNLEIKIIDF 566 Score = 55.1 bits (131), Expect = 2e-06 Identities = 31/92 (33%), Positives = 44/92 (47%), Gaps = 9/92 (9%) Frame = +3 Query: 2151 THEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQNLRFPDN 2330 T Y APE++ +G+ + D W+ GV LY +L G+ PF+ T + V + Sbjct: 585 TLHYAAPELLNQNGYDESCDLWSLGVILYTMLSGQVPFQSHDRSLTCTSAVEIMKKIKKG 644 Query: 2331 PV---------VSSNAKDLIRGLLVKEPENRL 2399 VS AKDLI+GLL +P RL Sbjct: 645 DFSFEGEAWKNVSQEAKDLIQGLLTVDPNKRL 676
>P34885:KPC1B_CAEEL Protein kinase C-like 1B - Caenorhabditis elegans| Length = 707 Score = 110 bits (276), Expect = 2e-23 Identities = 64/153 (41%), Positives = 89/153 (58%), Gaps = 1/153 (0%) Frame = +3 Query: 1431 GPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREIL 1610 G L + +F +K LG G G V LAE +D ++A+K++ + ++ + E+ IL Sbjct: 371 GTLSIHDFTFMKVLGKGSFGKVMLAERKGTDEVYAIKILKKDVIVQDDDVECTMCEKRIL 430 Query: 1611 EML-DHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLL 1787 + HPFL L++ F T + VMEY GGDL + Q Q R F E ARFY AEV Sbjct: 431 SLAAKHPFLTALHSSFQTSDRLFFVMEYVNGGDL--MFQIQRARKFDESRARFYAAEVTC 488 Query: 1788 ALEYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 AL++LH VIYRDLK +NIL+ +GH L+DF Sbjct: 489 ALQFLHRNDVIYRDLKLDNILLDAEGHCRLADF 521 Score = 81.3 bits (199), Expect = 2e-14 Identities = 39/123 (31%), Positives = 70/123 (56%), Gaps = 5/123 (4%) Frame = +3 Query: 2133 SNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQN 2312 +++F GT +Y+APEI++ +G +VDWW GV +YE++ G+ PF D+ +++ + Sbjct: 534 TSTFCGTPDYIAPEILQEMEYGVSVDWWALGVLMYEMMAGQPPFEADNEDDLFEAILNDD 593 Query: 2313 LRFPDNPVVSSNAKDLIRGLLVKEPENRLGTL---RGAAEIKQHPFFEGLNWALI--RSV 2477 + +P +S A ++++ + K RLG + G I+ HPFF ++W + R V Sbjct: 594 VLYP--VWLSKEAVNILKAFMTKNAGKRLGCVVSQGGEDAIRAHPFFREIDWDALESRQV 651 Query: 2478 APP 2486 PP Sbjct: 652 KPP 654
>Q6IP76:AKT2B_XENLA RAC-beta serine/threonine-protein kinase-B - Xenopus laevis (African| clawed frog) Length = 485 Score = 110 bits (276), Expect = 2e-23 Identities = 71/225 (31%), Positives = 108/225 (48%), Gaps = 9/225 (4%) Frame = +3 Query: 1239 ERSSEWL----TLEKGERSQNSKSSISE-----YGCSTSISDESQFGLYGYNNRPHMVKD 1391 E EW+ T+ G ++Q + E YG + +S Q + RP + Sbjct: 95 EEREEWIIAIQTVANGLKNQVPEDEEEEAMEVKYGSPSDVSSAEQMDVAMSKGRPKVT-- 152 Query: 1392 LCWITIRQLALQQGPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISR 1571 +++F LK LG G G V L + +A+K++ E +I++ Sbjct: 153 -----------------MNDFDYLKLLGKGTFGKVILVREKATGLYYAMKILRKEVIIAK 195 Query: 1572 KKMLRAQAEREILEMLDHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPE 1751 ++ E +L+ HPFL L F T + C VMEY GG+L R+ R F E Sbjct: 196 DEVAHTLTESRVLQNTKHPFLTGLKYAFQTSDRLCFVMEYANGGELFFHLSRE--RVFTE 253 Query: 1752 PSARFYVAEVLLALEYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 ARFY AE++ ALEYLH V+YRD+K EN+++ DGH+ ++DF Sbjct: 254 DRARFYGAEIVSALEYLHSRNVVYRDIKLENLMLDKDGHVKITDF 298 Score = 95.5 bits (236), Expect = 1e-18 Identities = 49/123 (39%), Positives = 72/123 (58%), Gaps = 3/123 (2%) Frame = +3 Query: 2127 ARSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVS 2306 A +F GT EYLAPE+++ + +G AVDWW GV +YE++ GR PF ++ ++ Sbjct: 309 ATMRTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFELILM 368 Query: 2307 QNLRFPDNPVVSSNAKDLIRGLLVKEPENRL-GTLRGAAEIKQHPFFEGLNWALI--RSV 2477 + RFP +S AK L+ GLL K+P+ RL G A E+ H FF +NW + R + Sbjct: 369 EETRFP--RTLSPEAKSLLAGLLKKDPKQRLGGGPDDAQEVMSHGFFASINWQDVTERKL 426 Query: 2478 APP 2486 +PP Sbjct: 427 SPP 429
>O75676:KS6A4_HUMAN Ribosomal protein S6 kinase alpha-4 - Homo sapiens (Human)| Length = 772 Score = 110 bits (275), Expect = 3e-23 Identities = 70/168 (41%), Positives = 99/168 (58%), Gaps = 6/168 (3%) Frame = +3 Query: 1401 ITIRQLALQQGPLGLDNFRLLKRLGCGDIGTVYLAELV---DSDCLFALKVMDIEYLISR 1571 IT L + + ++NF LLK LG G G V+L D+ L+A+KV+ L+ R Sbjct: 16 ITEANLTGHEEKVSVENFELLKVLGTGAYGKVFLVRKAGGHDAGKLYAMKVLRKAALVQR 75 Query: 1572 KKMLR-AQAEREILEMLDH-PFLPTLYAHFTTDNLSCLVMEYCPGGDLHV-LRQRQPGRS 1742 K + ER +LE++ PFL TL+ F TD L+++Y GG++ L QRQ Sbjct: 76 AKTQEHTRTERSVLELVRQAPFLVTLHYAFQTDAKLHLILDYVSGGEMFTHLYQRQ---Y 132 Query: 1743 FPEPSARFYVAEVLLALEYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 F E R Y E++LALE+LH LG+IYRDLK EN+L+ +GHI+L+DF Sbjct: 133 FKEAEVRVYGGEIVLALEHLHKLGIIYRDLKLENVLLDSEGHIVLTDF 180 Score = 106 bits (264), Expect = 6e-22 Identities = 60/128 (46%), Positives = 80/128 (62%), Gaps = 5/128 (3%) Frame = +3 Query: 2130 RSNSFVGTHEYLAPEIIKGD-GHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVS 2306 R+ SF GT EY+APEII+ GHG AVDWW+ G+ L+ELL G +PF G T A V Sbjct: 193 RTFSFCGTIEYMAPEIIRSKTGHGKAVDWWSLGILLFELLTGASPFTLEGERNTQAEVSR 252 Query: 2307 QNLRF--PDNPVVSSNAKDLIRGLLVKEPENRLGT-LRGAAEIKQHPFFEGLNW-ALIRS 2474 + L+ P P + A+DL++ LL K+P+ RLG +GA E++ HPFF+GL+W AL Sbjct: 253 RILKCSPPFPPRIGPVAQDLLQRLLCKDPKKRLGAGPQGAQEVRNHPFFQGLDWVALAAR 312 Query: 2475 VAPPETRP 2498 P RP Sbjct: 313 KIPAPFRP 320 Score = 54.7 bits (130), Expect = 2e-06 Identities = 35/101 (34%), Positives = 53/101 (52%), Gaps = 11/101 (10%) Frame = +3 Query: 2151 THEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFR---GPGNDETLANVVSQ---- 2309 T +Y APE++ G+ + D W+ GV LY +L G+ PF+ G G A ++ + Sbjct: 572 TLQYAAPELLAQQGYDESCDLWSLGVILYMMLSGQVPFQGASGQGGQSQAAEIMCKIREG 631 Query: 2310 --NLRFPDNPVVSSNAKDLIRGLLVKEPENRLGT--LRGAA 2420 +L VS AK+L+RGLL +P RL LRG++ Sbjct: 632 RFSLDGEAWQGVSEEAKELVRGLLTVDPAKRLKLEGLRGSS 672 Score = 49.7 bits (117), Expect = 7e-05 Identities = 46/168 (27%), Positives = 76/168 (45%), Gaps = 4/168 (2%) Frame = +3 Query: 1371 RPHMVKDLCWITIRQLALQQGPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMD 1550 R M++D + +L L++ LG +F + +R G FA+K++ Sbjct: 395 RSAMMQDSPFFQQYELDLREPALGQGSFSVCRRCRQRQSGQE-----------FAVKILS 443 Query: 1551 IEYLISRKKMLRAQAEREILEML---DHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLR 1721 + L A +RE+ + HP + L+ + LV+E GG+L L Sbjct: 444 --------RRLEANTQREVAALRLCQSHPNVVNLHEVHHDQLHTYLVLELLRGGEL--LE 493 Query: 1722 QRQPGRSFPEPSARFYVAEVLLALEYLHM-LGVIYRDLKPENILVRDD 1862 + R F E A + ++ A+ ++H GV++RDLKPENIL DD Sbjct: 494 HIRKKRHFSESEASQILRSLVSAVSFMHEEAGVVHRDLKPENILYADD 541
>P22612:KAPCG_HUMAN cAMP-dependent protein kinase, gamma-catalytic subunit - Homo sapiens| (Human) Length = 351 Score = 110 bits (275), Expect = 3e-23 Identities = 60/153 (39%), Positives = 92/153 (60%) Frame = +3 Query: 1428 QGPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREI 1607 Q D F L+ LG G G V L ++ +A+K+++ + ++ K++ E+ I Sbjct: 36 QNTASSDQFERLRTLGMGSFGRVMLVRHQETGGHYAMKILNKQKVVKMKQVEHILNEKRI 95 Query: 1608 LEMLDHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLL 1787 L+ +D PFL L F ++ LVMEY PGG++ QR GR F EP A FY A+V+L Sbjct: 96 LQAIDFPFLVKLQFSFKDNSYLYLVMEYVPGGEMFSRLQRV-GR-FSEPHACFYAAQVVL 153 Query: 1788 ALEYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 A++YLH L +I+RDLKPEN+L+ G++ ++DF Sbjct: 154 AVQYLHSLDLIHRDLKPENLLIDQQGYLQVTDF 186 Score = 85.9 bits (211), Expect = 8e-16 Identities = 47/116 (40%), Positives = 63/116 (54%), Gaps = 1/116 (0%) Frame = +3 Query: 2124 EARSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVV 2303 + R+ + GT EYLAPEII G+ AVDWW GV +YE+ G PF + +V Sbjct: 193 KGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAVGFPPFYADQPIQIYEKIV 252 Query: 2304 SQNLRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLR-GAAEIKQHPFFEGLNWALI 2468 S +RFP +SS+ K L+R LL + R G LR G +IK H +F +W I Sbjct: 253 SGRVRFPSK--LSSDLKHLLRSLLQVDLTKRFGNLRNGVGDIKNHKWFATTSWIAI 306
>P47197:AKT2_RAT RAC-beta serine/threonine-protein kinase - Rattus norvegicus (Rat)| Length = 481 Score = 110 bits (275), Expect = 3e-23 Identities = 60/148 (40%), Positives = 86/148 (58%) Frame = +3 Query: 1443 LDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEMLD 1622 +++F LK LG G G V L + +A+K++ E +I++ ++ E +L+ Sbjct: 149 MNDFDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTVTESRVLQNTR 208 Query: 1623 HPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALEYL 1802 HPFL L F T + C VMEY GGDL R+ R F E ARFY AE++ ALEYL Sbjct: 209 HPFLTALKYAFQTHDRLCFVMEYANGGDLFFHLSRE--RVFTEDRARFYGAEIVSALEYL 266 Query: 1803 HMLGVIYRDLKPENILVRDDGHIMLSDF 1886 H V+YRD+K EN+++ DGHI ++DF Sbjct: 267 HSTDVVYRDIKLENLMLDKDGHIKITDF 294 Score = 93.6 bits (231), Expect = 4e-18 Identities = 47/123 (38%), Positives = 72/123 (58%), Gaps = 3/123 (2%) Frame = +3 Query: 2127 ARSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVS 2306 A +F GT EYLAPE+++ + +G AVDWW GV +YE++ GR PF ++ ++ Sbjct: 305 ATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFELILM 364 Query: 2307 QNLRFPDNPVVSSNAKDLIRGLLVKEPENRL-GTLRGAAEIKQHPFFEGLNW--ALIRSV 2477 + +RFP + AK L+ GLL K+P+ RL G A E+ +H FF +NW + + + Sbjct: 365 EEIRFP--RTLGPEAKSLLAGLLKKDPKQRLGGGPSDAKEVMEHRFFLSINWQDVVQKKL 422 Query: 2478 APP 2486 PP Sbjct: 423 LPP 425
>P18961:YPK2_YEAST Serine/threonine-protein kinase YPK2/YKR2 - Saccharomyces cerevisiae| (Baker's yeast) Length = 677 Score = 110 bits (274), Expect = 4e-23 Identities = 66/162 (40%), Positives = 93/162 (57%) Frame = +3 Query: 1401 ITIRQLALQQGPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKM 1580 IT+ + PL +D+F LLK +G G G V D+ ++ALK + Y++S+ ++ Sbjct: 327 ITVDYKPSKNKPLSIDDFDLLKVIGKGSFGKVMQVRKKDTQKIYALKALRKAYIVSKCEV 386 Query: 1581 LRAQAEREILEMLDHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSA 1760 AER +L +D PF+ L F + LV+ + GG+L Q + GR F + Sbjct: 387 THTLAERTVLARVDCPFIVPLKFSFQSPEKLYLVLAFINGGELFYHLQHE-GR-FSLARS 444 Query: 1761 RFYVAEVLLALEYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 RFY+AE+L AL+ LH L VIYRDLKPENIL+ GHI L DF Sbjct: 445 RFYIAELLCALDSLHKLDVIYRDLKPENILLDYQGHIALCDF 486 Score = 100 bits (249), Expect = 3e-20 Identities = 50/121 (41%), Positives = 72/121 (59%), Gaps = 2/121 (1%) Frame = +3 Query: 2130 RSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQ 2309 ++++F GT EYLAPEI+ G G+ VDWWT G+ LYE++ G P+ ++ Q Sbjct: 498 KTDTFCGTPEYLAPEILLGQGYTKTVDWWTLGILLYEMMTGLPPYYDENVPVMYKKILQQ 557 Query: 2310 NLRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPFFEGLNW--ALIRSVAP 2483 L FPD AKDL+ GLL ++P RLG + G EI+ HPFF+ ++W L++ P Sbjct: 558 PLLFPDG--FDPAAKDLLIGLLSRDPSRRLG-VNGTDEIRNHPFFKDISWKKLLLKGYIP 614 Query: 2484 P 2486 P Sbjct: 615 P 615
>Q9QZS5:SGK2_MOUSE Serine/threonine-protein kinase Sgk2 - Mus musculus (Mouse)| Length = 367 Score = 110 bits (274), Expect = 4e-23 Identities = 63/147 (42%), Positives = 87/147 (59%), Gaps = 1/147 (0%) Frame = +3 Query: 1449 NFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREIL-EMLDH 1625 +F LK +G G+ G V LA+ +A+KV+ + ++ K+ AER +L + + H Sbjct: 34 DFDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKNKEQNHIMAERNVLLKNVRH 93 Query: 1626 PFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALEYLH 1805 PFL L F T V++Y GG+L QR+ R F EP ARFY AEV A+ YLH Sbjct: 94 PFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRE--RRFLEPRARFYTAEVASAIGYLH 151 Query: 1806 MLGVIYRDLKPENILVRDDGHIMLSDF 1886 L +IYRDLKPENIL+ GH++L+DF Sbjct: 152 SLNIIYRDLKPENILLDCQGHVVLTDF 178 Score = 94.0 bits (232), Expect = 3e-18 Identities = 49/116 (42%), Positives = 68/116 (58%) Frame = +3 Query: 2112 VEPTEARSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETL 2291 VEP E S +F GT EYLAPE+++ + + AVDWW G LYE+L+G PF + Sbjct: 185 VEPEETTS-TFCGTPEYLAPEVLRKEPYDRAVDWWCLGAVLYEMLHGLPPFFNTDVAQMY 243 Query: 2292 ANVVSQNLRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPFFEGLNW 2459 N++ Q L+ P V+ A DL++GLL K+ RLG+ +IK H FF +NW Sbjct: 244 ENILHQPLQIPGGRTVA--ACDLLQGLLHKDQRQRLGSKEDFLDIKNHMFFSPINW 297
>P36582:PCK1_SCHPO Protein kinase C-like 1 - Schizosaccharomyces pombe (Fission yeast)| Length = 988 Score = 110 bits (274), Expect = 4e-23 Identities = 65/151 (43%), Positives = 89/151 (58%), Gaps = 3/151 (1%) Frame = +3 Query: 1443 LDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEMLD 1622 LD+F L LG G+ G V LAE + +A+KV+ E ++ +++ + E+ + E+ + Sbjct: 661 LDDFTFLAVLGKGNFGKVMLAEYKVNKKFYAIKVLKKEAILKNEELESLKTEKHVFEVAN 720 Query: 1623 ---HPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLAL 1793 HPFL L+A F T VMEY GGDL V QRQ F ARFY AEV LAL Sbjct: 721 KEKHPFLLNLFASFQTSTRVYFVMEYILGGDLMVHIQRQ---QFSVKRARFYGAEVCLAL 777 Query: 1794 EYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 +Y H G+ YRDLK +NIL+ DGHI ++D+ Sbjct: 778 KYFHENGIAYRDLKLDNILLCPDGHIRIADY 808 Score = 92.8 bits (229), Expect = 7e-18 Identities = 46/124 (37%), Positives = 74/124 (59%), Gaps = 2/124 (1%) Frame = +3 Query: 2133 SNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQN 2312 +++F GT E++APEI+ + VDWW FGV +Y++L G++PF+G +E ++S Sbjct: 821 TSTFCGTPEFMAPEILLEQQYSKDVDWWAFGVLMYQMLLGQSPFKGEDEEEIFDAILSDE 880 Query: 2313 LRFPDNPVVSSNAKDLIRGLLVKEPENRLGT-LRGAAEIKQHPFFEGLNW-ALIRSVAPP 2486 FP N + ++A L+RGLL ++P RLG+ + A E+ HPFF + W L + P Sbjct: 881 PLFPIN--MPADAVSLLRGLLTRDPNQRLGSGPKDANEVMAHPFFASIVWDDLYNKLYEP 938 Query: 2487 ETRP 2498 +P Sbjct: 939 SYKP 942
>P10666:KS6AB_XENLA Ribosomal protein S6 kinase 2 beta - Xenopus laevis (African clawed| frog) Length = 629 Score = 110 bits (274), Expect = 4e-23 Identities = 62/149 (41%), Positives = 94/149 (63%), Gaps = 3/149 (2%) Frame = +3 Query: 1449 NFRLLKRLGCGDIGTVYLAELV---DSDCLFALKVMDIEYLISRKKMLRAQAEREILEML 1619 +F LLK LG G G V+L + D++ L+A+KV+ L R ++ R + ER+IL + Sbjct: 61 HFVLLKVLGQGSFGKVFLVRKITPPDANQLYAMKVLKKATLKVRDRV-RTKMERDILADV 119 Query: 1620 DHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALEY 1799 HPF+ L+ F T+ L++++ GGDL ++ F E +FY+AE+ L L++ Sbjct: 120 HHPFVVRLHYAFQTEGKLYLILDFLRGGDLFTRLSKEV--MFTEEDVKFYLAELALGLDH 177 Query: 1800 LHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 LH LG+IYRDLKPENIL+ ++GHI L+DF Sbjct: 178 LHSLGIIYRDLKPENILLDEEGHIKLTDF 206 Score = 102 bits (255), Expect = 7e-21 Identities = 48/124 (38%), Positives = 76/124 (61%), Gaps = 3/124 (2%) Frame = +3 Query: 2124 EARSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVV 2303 E ++ SF GT EY+APE++ GH DWW++GV ++E+L G PF+G ET+ ++ Sbjct: 216 EKKAYSFCGTVEYMAPEVVNRQGHSHGADWWSYGVLMFEMLTGSLPFQGKDRKETMTLIL 275 Query: 2304 SQNLRFPDNPVVSSNAKDLIRGLLVKEPENRLGT-LRGAAEIKQHPFFEGLNWALI--RS 2474 L P +S+ A+ L+R L + NRLG+ + GA E+K+HPFF ++W + R Sbjct: 276 KAKLGMPQ--FLSNEAQSLLRALFKRNATNRLGSGVEGAEELKRHPFFSTIDWNKLYRRE 333 Query: 2475 VAPP 2486 ++PP Sbjct: 334 LSPP 337 Score = 50.4 bits (119), Expect = 4e-05 Identities = 45/142 (31%), Positives = 64/142 (45%), Gaps = 3/142 (2%) Frame = +3 Query: 1446 DNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEML-D 1622 D + + + +G G ++ +A+KV+D K E EIL Sbjct: 414 DVYTVRETIGVGSYSVCKRCVHKGTNMEYAVKVID-------KSKRDPSEEIEILRRYGQ 466 Query: 1623 HPFLPTLYAHFTTDNLSCLVMEYCPGGDL--HVLRQRQPGRSFPEPSARFYVAEVLLALE 1796 HP + TL + N LV E GG+L +LRQ+ F E A + V +E Sbjct: 467 HPNIITLKDVYEECNSIYLVTELMRGGELLDRILRQK----FFSEREACSVLFTVCKTVE 522 Query: 1797 YLHMLGVIYRDLKPENILVRDD 1862 YLH GV++RDLKP NIL D+ Sbjct: 523 YLHSQGVVHRDLKPSNILYVDE 544 Score = 47.0 bits (110), Expect = 4e-04 Identities = 23/55 (41%), Positives = 34/55 (61%), Gaps = 3/55 (5%) Frame = +3 Query: 2151 THEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPF-RGPGN--DETLANVVS 2306 T ++APE++K G+ D W+ G+ LY +L G TPF GPG+ +E LA + S Sbjct: 575 TANFVAPEVLKRQGYDEGCDIWSLGILLYTMLAGYTPFANGPGDTPEEILARIGS 629
>P10665:KS6AA_XENLA Ribosomal protein S6 kinase 2 alpha - Xenopus laevis (African clawed| frog) Length = 733 Score = 110 bits (274), Expect = 4e-23 Identities = 62/149 (41%), Positives = 94/149 (63%), Gaps = 3/149 (2%) Frame = +3 Query: 1449 NFRLLKRLGCGDIGTVYLAELV---DSDCLFALKVMDIEYLISRKKMLRAQAEREILEML 1619 +F LLK LG G G V+L + D++ L+A+KV+ L R ++ R + ER+IL + Sbjct: 61 DFVLLKVLGQGSFGKVFLVRKITPPDANQLYAMKVLKKATLKVRDRV-RTKMERDILADV 119 Query: 1620 DHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALEY 1799 HPF+ L+ F T+ L++++ GGDL ++ F E +FY+AE+ L L++ Sbjct: 120 HHPFVVRLHYAFQTEGKLYLILDFLRGGDLFTRLSKEV--MFTEEDVKFYLAELALGLDH 177 Query: 1800 LHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 LH LG+IYRDLKPENIL+ ++GHI L+DF Sbjct: 178 LHSLGIIYRDLKPENILLDEEGHIKLTDF 206 Score = 104 bits (259), Expect = 2e-21 Identities = 49/124 (39%), Positives = 77/124 (62%), Gaps = 3/124 (2%) Frame = +3 Query: 2124 EARSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVV 2303 E ++ SF GT EY+APE++ GH + DWW++GV ++E+L G PF+G ET+ ++ Sbjct: 216 EKKAYSFCGTVEYMAPEVVNRQGHSHSADWWSYGVLMFEMLTGSLPFQGKDRKETMTLIL 275 Query: 2304 SQNLRFPDNPVVSSNAKDLIRGLLVKEPENRLGT-LRGAAEIKQHPFFEGLNWALI--RS 2474 L P +S+ A+ L+R L + P NRLG+ + GA EIK+ PFF ++W + R Sbjct: 276 KAKLGMPQ--FLSNEAQSLLRALFKRNPTNRLGSAMEGAEEIKRQPFFSTIDWNKLFRRE 333 Query: 2475 VAPP 2486 ++PP Sbjct: 334 MSPP 337 Score = 55.5 bits (132), Expect = 1e-06 Identities = 36/100 (36%), Positives = 53/100 (53%), Gaps = 5/100 (5%) Frame = +3 Query: 2151 THEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFR---GPGNDETLANVVSQ--NL 2315 T ++APE++K G+ D W+ G+ LY +L G TPF G +E LA + S L Sbjct: 575 TANFVAPEVLKRQGYDEGCDIWSLGILLYTMLAGYTPFANGLGDTPEEILARIGSGKFTL 634 Query: 2316 RFPDNPVVSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQH 2435 R + VS+ AKDL+ +L +P RL A ++ QH Sbjct: 635 RGGNWNTVSAAAKDLVSRMLHVDPHKRL----TAKQVLQH 670 Score = 46.2 bits (108), Expect = 7e-04 Identities = 43/145 (29%), Positives = 64/145 (44%), Gaps = 3/145 (2%) Frame = +3 Query: 1437 LGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEM 1616 L +D + + + +G G ++ +A+KV+D K E EIL Sbjct: 411 LFMDVYTVRETIGVGSYSVCKRCVHKGTNMEYAVKVID-------KTKRDPSEEIEILRR 463 Query: 1617 L-DHPFLPTLYAHFTTDNLSCLVMEYCPGGDL--HVLRQRQPGRSFPEPSARFYVAEVLL 1787 HP + L + N +V E GG+L +LRQ+ F E A + V Sbjct: 464 YGQHPNIIALKDVYKEGNSIYVVTELMRGGELLDRILRQK----FFSEREASSVLFTVCK 519 Query: 1788 ALEYLHMLGVIYRDLKPENILVRDD 1862 +E LH GV++RDLKP NIL D+ Sbjct: 520 TVENLHSQGVVHRDLKPSNILYVDE 544
>Q9Z2B9:KS6A4_MOUSE Ribosomal protein S6 kinase alpha-4 - Mus musculus (Mouse)| Length = 773 Score = 110 bits (274), Expect = 4e-23 Identities = 70/168 (41%), Positives = 99/168 (58%), Gaps = 6/168 (3%) Frame = +3 Query: 1401 ITIRQLALQQGPLGLDNFRLLKRLGCGDIGTVYLAELV---DSDCLFALKVMDIEYLISR 1571 IT L + + ++NF LLK LG G G V+L D+ L+A+KV+ L+ R Sbjct: 16 ITEANLTGHEEKVSVENFALLKVLGTGAYGKVFLVRKTGGHDAGKLYAMKVLRKAALVQR 75 Query: 1572 KKMLR-AQAEREILEMLDH-PFLPTLYAHFTTDNLSCLVMEYCPGGDLHV-LRQRQPGRS 1742 K + ER +LE++ PFL TL+ F TD L+++Y GG++ L QRQ Sbjct: 76 AKTQEHTRTERSVLELVRQAPFLVTLHYAFQTDAKLHLILDYVSGGEMFTHLYQRQ---Y 132 Query: 1743 FPEPSARFYVAEVLLALEYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 F E R Y E++LALE+LH LG+IYRDLK EN+L+ +GHI+L+DF Sbjct: 133 FKEAEVRVYGGEIVLALEHLHKLGIIYRDLKLENVLLDSEGHIVLTDF 180 Score = 105 bits (261), Expect = 1e-21 Identities = 61/128 (47%), Positives = 81/128 (63%), Gaps = 5/128 (3%) Frame = +3 Query: 2130 RSNSFVGTHEYLAPEIIKGD-GHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVS 2306 R+ SF GT EY+APEII+ GHG AVDWW+ G+ L+ELL G +PF G T A V Sbjct: 193 RTFSFCGTIEYMAPEIIRSKAGHGKAVDWWSLGILLFELLTGASPFTLEGERNTQAEVSR 252 Query: 2307 QNLR-FPDNPV-VSSNAKDLIRGLLVKEPENRLGT-LRGAAEIKQHPFFEGLN-WALIRS 2474 + L+ P P+ + A+DL++ LL K+P+ RLG +GA E+K HPFF+GL+ WAL Sbjct: 253 RILKCSPPFPLRIGPVAQDLLQRLLCKDPKKRLGAGPQGAQEVKSHPFFQGLDWWALAAR 312 Query: 2475 VAPPETRP 2498 P RP Sbjct: 313 KIPAPFRP 320 Score = 54.3 bits (129), Expect = 3e-06 Identities = 32/92 (34%), Positives = 48/92 (52%), Gaps = 9/92 (9%) Frame = +3 Query: 2151 THEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFR---GPGNDETLANVVSQ---- 2309 T +Y APE++ G+ + D W+ GV LY +L G+ PF+ G G A ++ + Sbjct: 572 TLQYAAPELLAQQGYDESCDLWSLGVILYMMLSGQVPFQGASGQGGQSQAAEIMCKIREG 631 Query: 2310 --NLRFPDNPVVSSNAKDLIRGLLVKEPENRL 2399 +L VS AK+L+RGLL +P RL Sbjct: 632 RFSLDGEAWQGVSEEAKELVRGLLTVDPAKRL 663 Score = 47.8 bits (112), Expect = 3e-04 Identities = 45/168 (26%), Positives = 75/168 (44%), Gaps = 4/168 (2%) Frame = +3 Query: 1371 RPHMVKDLCWITIRQLALQQGPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMD 1550 R M++D + +L L++ LG +F + +R G FA+K++ Sbjct: 395 RSAMMQDSPFFQQYELDLREPALGQGSFSVCRRCRQRQSGQE-----------FAVKILS 443 Query: 1551 IEYLISRKKMLRAQAEREILEML---DHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLR 1721 + L +RE+ + HP + L+ + LV+E GG+L L Sbjct: 444 --------RRLEENTQREVAALRLCQSHPNVVNLHEVLHDQLHTYLVLELLRGGEL--LE 493 Query: 1722 QRQPGRSFPEPSARFYVAEVLLALEYLHM-LGVIYRDLKPENILVRDD 1862 + R F E A + ++ A+ ++H GV++RDLKPENIL DD Sbjct: 494 HIRKKRLFSESEASQILRSLVSAVSFMHEEAGVVHRDLKPENILYADD 541
>P40376:KAPB_SCHPO cAMP-dependent protein kinase catalytic subunit - Schizosaccharomyces| pombe (Fission yeast) Length = 512 Score = 110 bits (274), Expect = 4e-23 Identities = 70/228 (30%), Positives = 115/228 (50%), Gaps = 4/228 (1%) Frame = +3 Query: 1215 NPGPEKSDERSSEWLTLEKGERSQNSKSSISEYGCSTSISDESQFGLYGYNNRPHMVKDL 1394 +P PE + SS+ ++S+ E G + GL + R V L Sbjct: 124 SPLPESASRSSSQ------SSHQRHSRDGRGELGSEHGERRSAMDGLRDRHIRKVRVSQL 177 Query: 1395 CWITIRQLA----LQQGPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYL 1562 + R++ + G+ +F L+ LG G G V+L + + +A+KV++ + + Sbjct: 178 LDLQRRRIRPADHTTKDRYGIQDFNFLQTLGTGSFGRVHLVQSNHNRLYYAIKVLEKKKI 237 Query: 1563 ISRKKMLRAQAEREILEMLDHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRS 1742 + K++ ER IL + HPF+ L+ F +VM++ GG+L L ++ Sbjct: 238 VDMKQIEHTCDERYILSRVQHPFITILWGTFQDAKNLFMVMDFAEGGELFSLLRKC--HR 295 Query: 1743 FPEPSARFYVAEVLLALEYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 FPE A+FY AEV+LAL+YLH ++YRDLKPEN+L+ GH+ + DF Sbjct: 296 FPEKVAKFYAAEVILALDYLHHNQIVYRDLKPENLLLDRFGHLKIVDF 343 Score = 70.1 bits (170), Expect = 5e-11 Identities = 39/120 (32%), Positives = 62/120 (51%), Gaps = 3/120 (2%) Frame = +3 Query: 2148 GTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQNLRFPD 2327 GT +YLAPEII + A DWW+ G+ ++E+L G PF + N++ + +P Sbjct: 359 GTPDYLAPEIISLKPYNKAADWWSLGILIFEMLAGYPPFYSENPMKLYENILEGKVNYPS 418 Query: 2328 NPVVSSNAKDLIRGLLVKEPENRLGTLR-GAAEIKQHPFFEGLNW--ALIRSVAPPETRP 2498 S + DL+ LL ++ R G L+ G+ +I HP+F ++W L R + P P Sbjct: 419 --YFSPASIDLLSHLLQRDITCRYGNLKDGSMDIIMHPWFRDISWDKILTRKIEVPYVPP 476
>P24723:KPCL_HUMAN Protein kinase C eta type - Homo sapiens (Human)| Length = 682 Score = 109 bits (273), Expect = 5e-23 Identities = 61/151 (40%), Positives = 90/151 (59%), Gaps = 1/151 (0%) Frame = +3 Query: 1437 LGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEM 1616 LG+DNF ++ LG G G V LA + ++ L+A+KV+ + ++ + E+ IL + Sbjct: 349 LGIDNFEFIRVLGKGSFGKVMLARVKETGDLYAVKVLKKDVILLDDDVECTMTEKRILSL 408 Query: 1617 L-DHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLAL 1793 +HPFL L+ F T + VME+ GGDL + Q R F E ARFY AE++ AL Sbjct: 409 ARNHPFLTQLFCCFQTPDRLFFVMEFVNGGDL--MFHIQKSRRFDEARARFYAAEIISAL 466 Query: 1794 EYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 +LH G+IYRDLK +N+L+ +GH L+DF Sbjct: 467 MFLHDKGIIYRDLKLDNVLLDHEGHCKLADF 497 Score = 87.4 bits (215), Expect = 3e-16 Identities = 43/120 (35%), Positives = 69/120 (57%), Gaps = 4/120 (3%) Frame = +3 Query: 2139 SFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQNLR 2318 +F GT +Y+APEI++ +G AVDWW GV LYE+L G PF D+ +++ + Sbjct: 512 TFCGTPDYIAPEILQEMLYGPAVDWWAMGVLLYEMLCGHAPFEAENEDDLFEAILNDEVV 571 Query: 2319 FPDNPVVSSNAKDLIRGLLVKEPENRLGTLRGAAE--IKQHPFFEGLNWALI--RSVAPP 2486 +P + +A +++ + K P RLG+L E I +HPFF+ ++WA + R + PP Sbjct: 572 YP--TWLHEDATGILKSFMTKNPTMRLGSLTQGGEHAILRHPFFKEIDWAQLNHRQIEPP 629
>P21137:KAPC_CAEEL cAMP-dependent protein kinase catalytic subunit - Caenorhabditis| elegans Length = 404 Score = 109 bits (273), Expect = 5e-23 Identities = 57/148 (38%), Positives = 92/148 (62%) Frame = +3 Query: 1443 LDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEMLD 1622 LD+F +K LG G G V L + S +A+K++D + ++ K++ E+ IL+ +D Sbjct: 78 LDDFDRIKTLGTGSFGRVMLVKHKQSGNYYAMKILDKQKVVKLKQVEHTLNEKRILQAID 137 Query: 1623 HPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALEYL 1802 PFL + F ++ +V+E+ GG++ R+ GR F EP +RFY A+++LA EYL Sbjct: 138 FPFLVNMTFSFKDNSNLYMVLEFISGGEMFS-HLRRIGR-FSEPHSRFYAAQIVLAFEYL 195 Query: 1803 HMLGVIYRDLKPENILVRDDGHIMLSDF 1886 H L +IYRDLKPEN+L+ G++ ++DF Sbjct: 196 HSLDLIYRDLKPENLLIDSTGYLKITDF 223 Score = 86.7 bits (213), Expect = 5e-16 Identities = 47/124 (37%), Positives = 68/124 (54%), Gaps = 3/124 (2%) Frame = +3 Query: 2124 EARSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVV 2303 + R+ + GT EYLAPEII G+ AVDWW GV +YE+ G PF + +V Sbjct: 230 KGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIV 289 Query: 2304 SQNLRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLR-GAAEIKQHPFFEGLNWALI--RS 2474 S ++FP + S+ KDL++ LL + R G L+ G A+IK H +F +W I + Sbjct: 290 SGKVKFPSH--FSNELKDLLKNLLQVDLTKRYGNLKNGVADIKNHKWFGSTDWIAIYQKK 347 Query: 2475 VAPP 2486 + PP Sbjct: 348 ITPP 351
>Q754N7:CBK1_ASHGO Serine/threonine-protein kinase CBK1 - Ashbya gossypii (Yeast)| (Eremothecium gossypii) Length = 719 Score = 109 bits (273), Expect = 5e-23 Identities = 60/157 (38%), Positives = 94/157 (59%) Frame = +3 Query: 1416 LALQQGPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQA 1595 L L++ L L++F +K +G G G V L + D+ ++A+K + + + ++ +A Sbjct: 298 LRLRRTRLSLEDFHTVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYKKDQLAHVKA 357 Query: 1596 EREILEMLDHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVA 1775 ER++L D P++ +LY F L+ME+ PGGDL + R + F E RFY+A Sbjct: 358 ERDVLAGSDSPWVVSLYYSFQDAQYLYLIMEFLPGGDLMTMLIRW--QIFTEDVTRFYMA 415 Query: 1776 EVLLALEYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 E +LA+E +H LG I+RD+KP+NIL+ GHI LSDF Sbjct: 416 ECILAIEAIHKLGFIHRDIKPDNILIDIRGHIKLSDF 452 Score = 97.8 bits (242), Expect = 2e-19 Identities = 54/118 (45%), Positives = 68/118 (57%), Gaps = 2/118 (1%) Frame = +3 Query: 2139 SFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVS--QN 2312 S VGT +Y+APEI G+G DWW+ G +YE L G PF ET +++ Q Sbjct: 530 STVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQT 589 Query: 2313 LRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPFFEGLNWALIRSVAPP 2486 L FPD+ +S A+DLIR LL + RLG GA EIK HPFF G++W IR V P Sbjct: 590 LVFPDDIHISYEAEDLIRRLL-SHADERLGR-HGANEIKNHPFFRGVDWETIRQVGAP 645
>P36583:PCK2_SCHPO Protein kinase C-like 2 - Schizosaccharomyces pombe (Fission yeast)| Length = 1016 Score = 109 bits (272), Expect = 7e-23 Identities = 59/153 (38%), Positives = 94/153 (61%), Gaps = 3/153 (1%) Frame = +3 Query: 1437 LGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEM 1616 +GL++F L LG G+ G V LAEL L+A+KV+ E+++ ++ ++E+ + + Sbjct: 678 IGLEDFTFLSVLGKGNFGKVMLAELKSEKQLYAIKVLKKEFILENDEVESTKSEKRVFLV 737 Query: 1617 LD---HPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLL 1787 + HPFL L++ F T+ VM++ GGDL + Q++ F A+FY AEV L Sbjct: 738 ANRERHPFLVNLHSCFQTETRIYFVMDFVSGGDLMLHIQQE---QFSRRRAQFYAAEVCL 794 Query: 1788 ALEYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 AL+Y H G+IYRDLK +NIL+ DGH+ ++D+ Sbjct: 795 ALKYFHDNGIIYRDLKLDNILLSPDGHVKVADY 827 Score = 85.1 bits (209), Expect = 1e-15 Identities = 38/108 (35%), Positives = 67/108 (62%), Gaps = 1/108 (0%) Frame = +3 Query: 2139 SFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQNLR 2318 +F GT E++APEI+ + +VDWW FGV +Y++L G++PFRG +E ++S Sbjct: 842 TFCGTPEFMAPEILLEQQYTRSVDWWAFGVLIYQMLLGQSPFRGEDEEEIFDAILSDEPL 901 Query: 2319 FPDNPVVSSNAKDLIRGLLVKEPENRLGT-LRGAAEIKQHPFFEGLNW 2459 +P + + ++ +++ LL ++P+ RLG+ A ++ HPFF +NW Sbjct: 902 YPIH--MPRDSVSILQQLLTRDPKKRLGSGPNDAEDVMTHPFFSNINW 947
>O60307:MAST3_HUMAN Microtubule-associated serine/threonine-protein kinase 3 - Homo| sapiens (Human) Length = 1309 Score = 109 bits (272), Expect = 7e-23 Identities = 58/146 (39%), Positives = 86/146 (58%) Frame = +3 Query: 1449 NFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEMLDHP 1628 +F +K + G G VYL D+ FA+K ++ + LI R ++ + ER+IL ++P Sbjct: 366 DFETIKLISNGAYGAVYLVRHRDTRQRFAIKKINKQNLILRNQIQQVFVERDILTFAENP 425 Query: 1629 FLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALEYLHM 1808 F+ +++ F T C+VMEY GGD L + P AR Y AE +LALEYLH Sbjct: 426 FVVSMFCSFETRRHLCMVMEYVEGGDCATLLKNMG--PLPVDMARLYFAETVLALEYLHN 483 Query: 1809 LGVIYRDLKPENILVRDDGHIMLSDF 1886 G+++RDLKP+N+L+ GHI L+DF Sbjct: 484 YGIVHRDLKPDNLLITSLGHIKLTDF 509 Score = 99.4 bits (246), Expect = 7e-20 Identities = 51/106 (48%), Positives = 67/106 (63%), Gaps = 1/106 (0%) Frame = +3 Query: 2148 GTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQNLRFPD 2327 GT EY+APE+I G+G VDWW GV LYE L G PF G +E VVS + +P+ Sbjct: 542 GTPEYIAPEVIFRQGYGKPVDWWAMGVVLYEFLVGCVPFFGDTPEELFGQVVSDEIMWPE 601 Query: 2328 -NPVVSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPFFEGLNWA 2462 + + ++A+DLI LL + P +RLGT G E+KQHPFF L+WA Sbjct: 602 GDEALPADAQDLITRLLRQSPLDRLGT-GGTHEVKQHPFFLALDWA 646
>Q64617:KPCL_RAT Protein kinase C eta type - Rattus norvegicus (Rat)| Length = 683 Score = 109 bits (272), Expect = 7e-23 Identities = 60/150 (40%), Positives = 89/150 (59%), Gaps = 1/150 (0%) Frame = +3 Query: 1440 GLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEML 1619 G+DNF ++ LG G G V LA + ++ L+A+KV+ + ++ + E+ IL + Sbjct: 351 GIDNFEFIRVLGKGSFGKVMLARIKETGELYAVKVLKKDVILQDDDVECTMTEKRILSLA 410 Query: 1620 -DHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALE 1796 +HPFL L+ F T + VME+ GGDL + Q R F E ARFY AE++ AL Sbjct: 411 RNHPFLTQLFCCFQTPDRLFFVMEFVNGGDL--MFHIQKSRRFDEARARFYAAEIISALM 468 Query: 1797 YLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 +LH G+IYRDLK +N+L+ +GH L+DF Sbjct: 469 FLHEKGIIYRDLKLDNVLLDHEGHCKLADF 498 Score = 87.0 bits (214), Expect = 4e-16 Identities = 43/120 (35%), Positives = 69/120 (57%), Gaps = 4/120 (3%) Frame = +3 Query: 2139 SFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQNLR 2318 +F GT +Y+APEI++ +G AVDWW GV LYE+L G PF D+ +++ + Sbjct: 513 TFCGTPDYIAPEILQEMLYGPAVDWWAMGVLLYEMLCGHAPFEAENEDDLFEAILNDEVV 572 Query: 2319 FPDNPVVSSNAKDLIRGLLVKEPENRLGTLR--GAAEIKQHPFFEGLNWALI--RSVAPP 2486 +P + +A +++ + K P RLG+L G EI +HPFF+ ++W + R + PP Sbjct: 573 YP--TWLHEDATGILKSFMTKNPTMRLGSLTQGGEHEILRHPFFKEIDWVQLNHRQLEPP 630
>P23298:KPCL_MOUSE Protein kinase C eta type - Mus musculus (Mouse)| Length = 683 Score = 109 bits (272), Expect = 7e-23 Identities = 60/150 (40%), Positives = 89/150 (59%), Gaps = 1/150 (0%) Frame = +3 Query: 1440 GLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEML 1619 G+DNF ++ LG G G V LA + ++ L+A+KV+ + ++ + E+ IL + Sbjct: 351 GIDNFEFIRVLGKGSFGKVMLARIKETGELYAVKVLKKDVILQDDDVECTMTEKRILSLA 410 Query: 1620 -DHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALE 1796 +HPFL L+ F T + VME+ GGDL + Q R F E ARFY AE++ AL Sbjct: 411 RNHPFLTQLFCCFQTPDRLFFVMEFVNGGDL--MFHIQKSRRFDEARARFYAAEIISALM 468 Query: 1797 YLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 +LH G+IYRDLK +N+L+ +GH L+DF Sbjct: 469 FLHEKGIIYRDLKLDNVLLDHEGHCKLADF 498 Score = 89.7 bits (221), Expect = 6e-17 Identities = 44/120 (36%), Positives = 71/120 (59%), Gaps = 4/120 (3%) Frame = +3 Query: 2139 SFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQNLR 2318 +F GT +Y+APEI++ +G AVDWW GV LYE+L G PF D+ +++ + Sbjct: 513 TFCGTPDYIAPEILQEMLYGPAVDWWAMGVLLYEMLCGHAPFEAENEDDLFEAILNDEVV 572 Query: 2319 FPDNPVVSSNAKDLIRGLLVKEPENRLGTLR--GAAEIKQHPFFEGLNWALI--RSVAPP 2486 +P + +A+ +++ + K P RLG+L G EI +HPFF+ ++WA + R + PP Sbjct: 573 YP--TWLHEDARGILKSFMTKNPTMRLGSLTQGGEHEILRHPFFKEIDWAQLNHRQLEPP 630
>P13678:KPC3_DROME Protein kinase C - Drosophila melanogaster (Fruit fly)| Length = 634 Score = 109 bits (272), Expect = 7e-23 Identities = 66/153 (43%), Positives = 89/153 (58%), Gaps = 1/153 (0%) Frame = +3 Query: 1431 GPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREIL 1610 G L +F +K LG G G V LAE +D ++A+KV+ + +I + E+ IL Sbjct: 296 GKCSLLDFNFIKVLGKGSFGKVMLAEKKGTDEIYAIKVLKKDAIIQDDDVDCTMTEKRIL 355 Query: 1611 EML-DHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLL 1787 + +HPFL L++ F T + VMEY GGDL + Q Q R F A FY AEV L Sbjct: 356 ALAANHPFLTALHSCFQTPDRLFFVMEYVNGGDL--MFQIQKARRFEASRAAFYAAEVTL 413 Query: 1788 ALEYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 AL++LH GVIYRDLK +NIL+ +GH L+DF Sbjct: 414 ALQFLHTHGVIYRDLKLDNILLDQEGHCKLADF 446 Score = 99.0 bits (245), Expect = 1e-19 Identities = 45/120 (37%), Positives = 73/120 (60%), Gaps = 2/120 (1%) Frame = +3 Query: 2133 SNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQN 2312 + +F GT +Y+APEI+K +G++VDWW GV +YE++ G+ PF DE +++ + Sbjct: 459 TTTFCGTPDYIAPEILKEQEYGASVDWWALGVLMYEMMAGQPPFEADNEDELFDSIMHDD 518 Query: 2313 LRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPFFEGLNWALI--RSVAPP 2486 + +P +S A +++G L K PE RLG EI++HPFF L+W + R++ PP Sbjct: 519 VLYP--VWLSREAVSILKGFLTKNPEQRLGCTGDENEIRKHPFFAKLDWKELEKRNIKPP 576
>Q7ZX15:AKT2A_XENLA RAC-beta serine/threonine-protein kinase-A - Xenopus laevis (African| clawed frog) Length = 486 Score = 109 bits (272), Expect = 7e-23 Identities = 58/148 (39%), Positives = 86/148 (58%) Frame = +3 Query: 1443 LDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEMLD 1622 +++F LK LG G G V L + +A+K++ E +I++ ++ E +L+ Sbjct: 154 MNDFDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTLTESRVLQNTK 213 Query: 1623 HPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALEYL 1802 HPFL L F T + C VMEY GG+L R+ R F E ARFY AE++ ALEYL Sbjct: 214 HPFLTALKYAFQTSDRLCFVMEYANGGELFFHLSRE--RVFTEDRARFYGAEIVSALEYL 271 Query: 1803 HMLGVIYRDLKPENILVRDDGHIMLSDF 1886 H V+YRD+K EN+++ DGH+ ++DF Sbjct: 272 HSRNVVYRDIKLENLMLDKDGHVKITDF 299 Score = 96.7 bits (239), Expect = 5e-19 Identities = 49/123 (39%), Positives = 72/123 (58%), Gaps = 3/123 (2%) Frame = +3 Query: 2127 ARSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVS 2306 A +F GT EYLAPE+++ + +G AVDWW GV +YE++ GR PF ++ ++ Sbjct: 310 ATMRTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFELILM 369 Query: 2307 QNLRFPDNPVVSSNAKDLIRGLLVKEPENRL-GTLRGAAEIKQHPFFEGLNWALI--RSV 2477 + +RFP +S AK L+ GLL K+P+ RL G A E+ H FF +NW + R + Sbjct: 370 EEIRFP--RTLSPEAKSLLAGLLKKDPKQRLGGGPNDAQEVMSHRFFVSINWQDVTERKL 427 Query: 2478 APP 2486 PP Sbjct: 428 TPP 430
>O62846:KAPCG_MACMU cAMP-dependent protein kinase, gamma-catalytic subunit - Macaca| mulatta (Rhesus macaque) Length = 209 Score = 108 bits (271), Expect = 9e-23 Identities = 60/153 (39%), Positives = 91/153 (59%) Frame = +3 Query: 1428 QGPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREI 1607 Q D F LK LG G G V L ++ +A+K++D + ++ K++ E+ I Sbjct: 35 QNTASSDQFERLKTLGTGSYGRVMLVRHRETGNHYAMKILDKQKVVRLKQVEHTLNEKRI 94 Query: 1608 LEMLDHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLL 1787 L+ ++ PFL L F ++ LVMEY PGG++ R+ GR F EP A FY A+V+L Sbjct: 95 LQAINFPFLVKLQFSFKDNSNLYLVMEYVPGGEMFS-HLRRVGR-FSEPQACFYAAQVVL 152 Query: 1788 ALEYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 A +YLH L +I+RDLKPEN+L+ G++ ++DF Sbjct: 153 AFQYLHSLDLIHRDLKPENLLIDQQGYLQVTDF 185
>Q6CFS5:CBK1_YARLI Serine/threonine-protein kinase CBK1 - Yarrowia lipolytica (Candida| lipolytica) Length = 588 Score = 108 bits (271), Expect = 9e-23 Identities = 59/157 (37%), Positives = 95/157 (60%) Frame = +3 Query: 1416 LALQQGPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQA 1595 L +++ + L++F +K +G G G V L + D+ ++A+K M + + +++ +A Sbjct: 195 LRMRRTRMALEDFVTVKVIGKGAFGEVRLVQKRDNGKIYAMKTMLKKEMDMKEQWAHVKA 254 Query: 1596 EREILEMLDHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVA 1775 ER++L D P++ +LY F D L+ME+ PGGDL + + F E RFY+A Sbjct: 255 ERDVLADSDSPWIVSLYFSFQDDLYLYLIMEFLPGGDLMTMLIKYD--VFSEDITRFYIA 312 Query: 1776 EVLLALEYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 E +LA+E +H LG I+RD+KP+NIL+ GHI LSDF Sbjct: 313 ECVLAIEAIHKLGFIHRDIKPDNILIDKTGHIKLSDF 349 Score = 101 bits (252), Expect = 1e-20 Identities = 52/118 (44%), Positives = 71/118 (60%), Gaps = 2/118 (1%) Frame = +3 Query: 2139 SFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVS--QN 2312 S VGT +Y+APEI G+G DWW+ G ++E L G PF ET +++ + Sbjct: 415 STVGTPDYIAPEIFVHQGYGQECDWWSLGAIMFECLVGWPPFCSEQPRETYHKIINWRET 474 Query: 2313 LRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPFFEGLNWALIRSVAPP 2486 L+FPD+ +S ++DLIR LL ENRLG + GA EIK HPFF G++W+ IR P Sbjct: 475 LQFPDDVHLSPESEDLIRRLLTSS-ENRLGRIGGANEIKSHPFFRGVDWSSIREFNAP 531
>Q9XTG7:AKT2_CAEEL Serine/threonine-protein kinase akt-2 - Caenorhabditis elegans| Length = 528 Score = 108 bits (271), Expect = 9e-23 Identities = 59/148 (39%), Positives = 84/148 (56%) Frame = +3 Query: 1443 LDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEMLD 1622 +D+F LK LG G G V L SD L+A+K++ E ++ R ++ E +L Sbjct: 177 MDDFDFLKVLGQGTFGKVILCREKSSDKLYAIKIIRKEMVVDRSEVAHTLTENRVLYACV 236 Query: 1623 HPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALEYL 1802 HPFL L F C VME+ GG+L QR ++F E RFY +E++LAL YL Sbjct: 237 HPFLTLLKYSFQAQYHICFVMEFANGGELFTHLQR--CKTFSEARTRFYGSEIILALGYL 294 Query: 1803 HMLGVIYRDLKPENILVRDDGHIMLSDF 1886 H ++YRD+K EN+L+ DGHI ++DF Sbjct: 295 HHRNIVYRDMKLENLLLDRDGHIKITDF 322 Score = 83.6 bits (205), Expect = 4e-15 Identities = 45/125 (36%), Positives = 72/125 (57%), Gaps = 2/125 (1%) Frame = +3 Query: 2130 RSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQ 2309 ++++F GT EYLAPE+I+ + +VDWW GV +YE++ GR PF N + + + Sbjct: 334 KTSTFCGTPEYLAPEVIEDIDYDRSVDWWGVGVVMYEMMCGRLPFSAKENGKLFELITTC 393 Query: 2310 NLRFPDNPVVSSNAKDLIRGLLVKEPENRLGT-LRGAAEIKQHPFFEGLNW-ALIRSVAP 2483 +L+FP+ +S A L+ GLL + P RLG A E+ + FF+ ++W A +R Sbjct: 394 DLKFPNR--LSPEAVTLLSGLLERVPAKRLGAGPDDAREVSRAEFFKDVDWEATLRKEVE 451 Query: 2484 PETRP 2498 P +P Sbjct: 452 PPFKP 456
>P12688:YPK1_YEAST Serine/threonine-protein kinase YPK1 - Saccharomyces cerevisiae| (Baker's yeast) Length = 680 Score = 108 bits (270), Expect = 1e-22 Identities = 63/151 (41%), Positives = 88/151 (58%) Frame = +3 Query: 1434 PLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILE 1613 PL +D+F LLK +G G G V D+ ++ALK + Y++S+ ++ AER +L Sbjct: 341 PLSIDDFDLLKVIGKGSFGKVMQVRKKDTQKVYALKAIRKSYIVSKSEVTHTLAERTVLA 400 Query: 1614 MLDHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLAL 1793 +D PF+ L F + V+ + GG+L Q++ GR F ARFY AE+L AL Sbjct: 401 RVDCPFIVPLKFSFQSPEKLYFVLAFINGGELFYHLQKE-GR-FDLSRARFYTAELLCAL 458 Query: 1794 EYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 + LH L V+YRDLKPENIL+ GHI L DF Sbjct: 459 DNLHKLDVVYRDLKPENILLDYQGHIALCDF 489 Score = 101 bits (251), Expect = 2e-20 Identities = 53/121 (43%), Positives = 74/121 (61%), Gaps = 2/121 (1%) Frame = +3 Query: 2130 RSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQ 2309 ++++F GT EYLAPE++ G G+ AVDWWT GV LYE+L G P+ + ++ + Sbjct: 501 KTDTFCGTPEYLAPELLLGLGYTKAVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQE 560 Query: 2310 NLRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPFFEGLNW--ALIRSVAP 2483 L FPD +AKDL+ GLL ++P RLG GA EI+ HPFF L+W L++ P Sbjct: 561 PLVFPDG--FDRDAKDLLIGLLSRDPTRRLG-YNGADEIRNHPFFSQLSWKRLLMKGYIP 617 Query: 2484 P 2486 P Sbjct: 618 P 618
>Q8R4U9:SGK2_RAT Serine/threonine-protein kinase Sgk2 - Rattus norvegicus (Rat)| Length = 367 Score = 108 bits (270), Expect = 1e-22 Identities = 62/147 (42%), Positives = 86/147 (58%), Gaps = 1/147 (0%) Frame = +3 Query: 1449 NFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREIL-EMLDH 1625 +F LK +G G+ G V LA+ +A+KV+ + ++ K+ AER +L + + H Sbjct: 34 DFDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKNKEQSHIMAERNVLLKNVRH 93 Query: 1626 PFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALEYLH 1805 PFL L F T V++Y GG+L QR+ F EP ARFY AEV A+ YLH Sbjct: 94 PFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRE--HRFLEPRARFYTAEVASAIGYLH 151 Query: 1806 MLGVIYRDLKPENILVRDDGHIMLSDF 1886 L +IYRDLKPENIL+ GH++L+DF Sbjct: 152 SLNIIYRDLKPENILLDCQGHVVLTDF 178 Score = 94.0 bits (232), Expect = 3e-18 Identities = 49/116 (42%), Positives = 68/116 (58%) Frame = +3 Query: 2112 VEPTEARSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETL 2291 VEP E S +F GT EYLAPE+++ + + AVDWW G LYE+L+G PF + Sbjct: 185 VEPEETTS-TFCGTPEYLAPEVLRKEPYDRAVDWWCLGAVLYEMLHGLPPFFNTDVAQMY 243 Query: 2292 ANVVSQNLRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPFFEGLNW 2459 N++ Q L+ P V+ A DL++GLL K+ RLG+ +IK H FF +NW Sbjct: 244 ENILHQPLQIPGGRTVA--ACDLLQGLLHKDQRQRLGSKEDFLDIKNHMFFSPINW 297
>O55173:PDPK1_RAT 3-phosphoinositide-dependent protein kinase 1 - Rattus norvegicus| (Rat) Length = 559 Score = 108 bits (270), Expect = 1e-22 Identities = 58/147 (39%), Positives = 86/147 (58%) Frame = +3 Query: 1446 DNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEMLDH 1625 ++F+ K LG G TV LA + + +A+K+++ ++I K+ ER+++ LDH Sbjct: 83 EDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDH 142 Query: 1626 PFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALEYLH 1805 PF LY F D + Y G+L L+ + SF E RFY AE++ ALEYLH Sbjct: 143 PFFVKLYFTFQDDEKLYFGLSYAKNGEL--LKYIRKIGSFDETCTRFYTAEIVSALEYLH 200 Query: 1806 MLGVIYRDLKPENILVRDDGHIMLSDF 1886 G+I+RDLKPENIL+ +D HI ++DF Sbjct: 201 GKGIIHRDLKPENILLNEDMHIQITDF 227 Score = 80.5 bits (197), Expect = 4e-14 Identities = 41/124 (33%), Positives = 63/124 (50%), Gaps = 2/124 (1%) Frame = +3 Query: 2124 EARSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVV 2303 +AR+NSFVGT +Y++PE++ + D W G +Y+L+ G PFR ++ Sbjct: 239 QARANSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKII 298 Query: 2304 SQNLRFPDNPVVSSNAKDLIRGLLVKEPENRLG--TLRGAAEIKQHPFFEGLNWALIRSV 2477 FP+ A+DL+ LLV + RLG + G +K HPFFE + W + Sbjct: 299 KLEYDFPEK--FFPKARDLVEKLLVLDATKRLGCEEMEGYGPLKAHPFFESITWENLHQQ 356 Query: 2478 APPE 2489 PP+ Sbjct: 357 TPPK 360
>Q9Z2A0:PDPK1_MOUSE 3-phosphoinositide-dependent protein kinase 1 - Mus musculus (Mouse)| Length = 559 Score = 108 bits (270), Expect = 1e-22 Identities = 58/147 (39%), Positives = 86/147 (58%) Frame = +3 Query: 1446 DNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEMLDH 1625 ++F+ K LG G TV LA + + +A+K+++ ++I K+ ER+++ LDH Sbjct: 83 EDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDH 142 Query: 1626 PFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALEYLH 1805 PF LY F D + Y G+L L+ + SF E RFY AE++ ALEYLH Sbjct: 143 PFFVKLYFTFQDDEKLYFGLSYAKNGEL--LKYIRKIGSFDETCTRFYTAEIVSALEYLH 200 Query: 1806 MLGVIYRDLKPENILVRDDGHIMLSDF 1886 G+I+RDLKPENIL+ +D HI ++DF Sbjct: 201 GKGIIHRDLKPENILLNEDMHIQITDF 227 Score = 81.6 bits (200), Expect = 2e-14 Identities = 42/127 (33%), Positives = 64/127 (50%), Gaps = 2/127 (1%) Frame = +3 Query: 2115 EPTEARSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLA 2294 E +AR+NSFVGT +Y++PE++ + D W G +Y+L+ G PFR Sbjct: 236 ESKQARANSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQ 295 Query: 2295 NVVSQNLRFPDNPVVSSNAKDLIRGLLVKEPENRLG--TLRGAAEIKQHPFFEGLNWALI 2468 ++ FP+ A+DL+ LLV + RLG + G +K HPFFE + W + Sbjct: 296 KIIKLEYHFPEK--FFPKARDLVEKLLVLDATKRLGCEEMEGYGPLKAHPFFETITWENL 353 Query: 2469 RSVAPPE 2489 PP+ Sbjct: 354 HQQTPPK 360
>O15530:PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 - Homo sapiens (Human)| Length = 556 Score = 108 bits (270), Expect = 1e-22 Identities = 58/147 (39%), Positives = 86/147 (58%) Frame = +3 Query: 1446 DNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEMLDH 1625 ++F+ K LG G TV LA + + +A+K+++ ++I K+ ER+++ LDH Sbjct: 80 EDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDH 139 Query: 1626 PFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALEYLH 1805 PF LY F D + Y G+L L+ + SF E RFY AE++ ALEYLH Sbjct: 140 PFFVKLYFTFQDDEKLYFGLSYAKNGEL--LKYIRKIGSFDETCTRFYTAEIVSALEYLH 197 Query: 1806 MLGVIYRDLKPENILVRDDGHIMLSDF 1886 G+I+RDLKPENIL+ +D HI ++DF Sbjct: 198 GKGIIHRDLKPENILLNEDMHIQITDF 224 Score = 81.3 bits (199), Expect = 2e-14 Identities = 42/127 (33%), Positives = 64/127 (50%), Gaps = 2/127 (1%) Frame = +3 Query: 2115 EPTEARSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLA 2294 E +AR+NSFVGT +Y++PE++ + D W G +Y+L+ G PFR Sbjct: 233 ESKQARANSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQ 292 Query: 2295 NVVSQNLRFPDNPVVSSNAKDLIRGLLVKEPENRLG--TLRGAAEIKQHPFFEGLNWALI 2468 ++ FP+ A+DL+ LLV + RLG + G +K HPFFE + W + Sbjct: 293 KIIKLEYDFPEK--FFPKARDLVEKLLVLDATKRLGCEEMEGYGPLKAHPFFESVTWENL 350 Query: 2469 RSVAPPE 2489 PP+ Sbjct: 351 HQQTPPK 357
>Q6PFQ0:KS6A6_DANRE Ribosomal protein S6 kinase alpha-6 - Danio rerio (Zebrafish)| (Brachydanio rerio) Length = 740 Score = 108 bits (270), Expect = 1e-22 Identities = 61/148 (41%), Positives = 93/148 (62%), Gaps = 3/148 (2%) Frame = +3 Query: 1452 FRLLKRLGCGDIGTVYLAELV---DSDCLFALKVMDIEYLISRKKMLRAQAEREILEMLD 1622 F LLK LG G G V+L + D+ L+A+KV+ L R ++ R + ER+IL ++ Sbjct: 67 FELLKVLGQGSFGKVFLVRKLMGPDAGQLYAMKVLKKASLKVRDRV-RTKMERDILVEVN 125 Query: 1623 HPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALEYL 1802 HPF+ L+ F T+ L++++ GGD+ ++ F E +FY+AE+ LAL++L Sbjct: 126 HPFIVKLHYAFQTEGKLYLILDFLRGGDVFTRLSKEV--MFTEEDVKFYLAELALALDHL 183 Query: 1803 HMLGVIYRDLKPENILVRDDGHIMLSDF 1886 H LG++YRDLKPENIL+ + GHI L+DF Sbjct: 184 HNLGIVYRDLKPENILLDEAGHIKLTDF 211 Score = 93.6 bits (231), Expect = 4e-18 Identities = 47/124 (37%), Positives = 72/124 (58%), Gaps = 3/124 (2%) Frame = +3 Query: 2124 EARSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVV 2303 + ++ SF GT EY+APE++ GH + DWW+ GV ++E+L G PF+G +ET+ ++ Sbjct: 221 DKKAYSFCGTVEYMAPEVVNRRGHTQSADWWSLGVLMFEMLTGTLPFQGKDRNETMNMIL 280 Query: 2304 SQNLRFPDNPVVSSNAKDLIRGLLVKEPENRLGT-LRGAAEIKQHPFFEGLNWALI--RS 2474 L P +S A+ L+R L + P NRLG G EIK+H FF ++W + R Sbjct: 281 KAKLGMPQ--FLSLEAQGLLRMLFKRNPSNRLGAGPDGVEEIKRHTFFSTIDWNKLYRRE 338 Query: 2475 VAPP 2486 + PP Sbjct: 339 LQPP 342 Score = 52.4 bits (124), Expect = 1e-05 Identities = 39/116 (33%), Positives = 53/116 (45%), Gaps = 3/116 (2%) Frame = +3 Query: 1524 CLFALKVMDIEYLISRKKMLRAQAEREILEML-DHPFLPTLYAHFTTDNLSCLVMEYCPG 1700 C+ + M+ I K E EIL HP + TL + LV E G Sbjct: 437 CIHRVTAMEFAVKIIDKSKRDPSEEIEILMRYGQHPNIITLKDVYDEGRFVYLVTELMKG 496 Query: 1701 GDL--HVLRQRQPGRSFPEPSARFYVAEVLLALEYLHMLGVIYRDLKPENILVRDD 1862 G+L +LRQ+ F E A + + ++YLH GV++RDLKP NIL DD Sbjct: 497 GELLDKILRQK----FFSEREASAVLYTITKTVDYLHCQGVVHRDLKPSNILYMDD 548 Score = 50.8 bits (120), Expect = 3e-05 Identities = 30/87 (34%), Positives = 45/87 (51%), Gaps = 5/87 (5%) Frame = +3 Query: 2151 THEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGND---ETLANVVSQNLRF 2321 T ++APE++ G+ +A D W+ GV LY +L G TPF ND E L + S Sbjct: 579 TANFVAPEVLMRQGYDAACDIWSLGVLLYTMLAGYTPFANGPNDTPEEILLRIGSGKFSL 638 Query: 2322 PDN--PVVSSNAKDLIRGLLVKEPENR 2396 VS ++KDL+ +L +P +R Sbjct: 639 SGGNWDSVSDSSKDLLSHMLHVDPHHR 665
>Q60823:AKT2_MOUSE RAC-beta serine/threonine-protein kinase - Mus musculus (Mouse)| Length = 481 Score = 108 bits (270), Expect = 1e-22 Identities = 59/148 (39%), Positives = 86/148 (58%) Frame = +3 Query: 1443 LDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEMLD 1622 +++F LK LG G G V L + +A+K++ E +I++ ++ E +L+ Sbjct: 149 MNDFDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTVTESRVLQNTR 208 Query: 1623 HPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALEYL 1802 HPFL L F T + C VMEY GG+L R+ R F E ARFY AE++ ALEYL Sbjct: 209 HPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSRE--RVFTEDRARFYGAEIVSALEYL 266 Query: 1803 HMLGVIYRDLKPENILVRDDGHIMLSDF 1886 H V+YRD+K EN+++ DGHI ++DF Sbjct: 267 HSRDVVYRDIKLENLMLDKDGHIKITDF 294 Score = 93.6 bits (231), Expect = 4e-18 Identities = 47/123 (38%), Positives = 72/123 (58%), Gaps = 3/123 (2%) Frame = +3 Query: 2127 ARSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVS 2306 A +F GT EYLAPE+++ + +G AVDWW GV +YE++ GR PF ++ ++ Sbjct: 305 ATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFELILM 364 Query: 2307 QNLRFPDNPVVSSNAKDLIRGLLVKEPENRL-GTLRGAAEIKQHPFFEGLNW--ALIRSV 2477 + +RFP + AK L+ GLL K+P+ RL G A E+ +H FF +NW + + + Sbjct: 365 EEIRFP--RTLGPEAKSLLAGLLKKDPKQRLGGGPSDAKEVMEHRFFLSINWQDVVQKKL 422 Query: 2478 APP 2486 PP Sbjct: 423 LPP 425
>P31751:AKT2_HUMAN RAC-beta serine/threonine-protein kinase - Homo sapiens (Human)| Length = 481 Score = 108 bits (270), Expect = 1e-22 Identities = 59/148 (39%), Positives = 86/148 (58%) Frame = +3 Query: 1443 LDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEMLD 1622 +++F LK LG G G V L + +A+K++ E +I++ ++ E +L+ Sbjct: 149 MNDFDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTVTESRVLQNTR 208 Query: 1623 HPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALEYL 1802 HPFL L F T + C VMEY GG+L R+ R F E ARFY AE++ ALEYL Sbjct: 209 HPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSRE--RVFTEERARFYGAEIVSALEYL 266 Query: 1803 HMLGVIYRDLKPENILVRDDGHIMLSDF 1886 H V+YRD+K EN+++ DGHI ++DF Sbjct: 267 HSRDVVYRDIKLENLMLDKDGHIKITDF 294 Score = 95.1 bits (235), Expect = 1e-18 Identities = 48/123 (39%), Positives = 73/123 (59%), Gaps = 3/123 (2%) Frame = +3 Query: 2127 ARSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVS 2306 A +F GT EYLAPE+++ + +G AVDWW GV +YE++ GR PF ++ ++ Sbjct: 305 ATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFELILM 364 Query: 2307 QNLRFPDNPVVSSNAKDLIRGLLVKEPENRL-GTLRGAAEIKQHPFFEGLNW--ALIRSV 2477 + +RFP +S AK L+ GLL K+P+ RL G A E+ +H FF +NW + + + Sbjct: 365 EEIRFP--RTLSPEAKSLLAGLLKKDPKQRLGGGPSDAKEVMEHRFFLSINWQDVVQKKL 422 Query: 2478 APP 2486 PP Sbjct: 423 LPP 425
>P51817:PRKX_HUMAN Serine/threonine-protein kinase PRKX - Homo sapiens (Human)| Length = 358 Score = 108 bits (269), Expect = 2e-22 Identities = 63/149 (42%), Positives = 88/149 (59%), Gaps = 1/149 (0%) Frame = +3 Query: 1443 LDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEMLD 1622 L +F L +G G G V+L + + FALKVM I +I K+ E+ +L+ + Sbjct: 46 LQDFDTLATVGTGTFGRVHLVKEKTAKHFFALKVMSIPDVIRLKQEQHVHNEKSVLKEVS 105 Query: 1623 HPFLPTLYAHFTTDNLSCLVMEYCPGGDLH-VLRQRQPGRSFPEPSARFYVAEVLLALEY 1799 HPFL L+ + + ++MEY PGG+L LR R GR F + FY AE++ A+EY Sbjct: 106 HPFLIRLFWTWHDERFLYMLMEYVPGGELFSYLRNR--GR-FSSTTGLFYSAEIICAIEY 162 Query: 1800 LHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 LH ++YRDLKPENIL+ DGHI L+DF Sbjct: 163 LHSKEIVYRDLKPENILLDRDGHIKLTDF 191 Score = 87.8 bits (216), Expect = 2e-16 Identities = 45/122 (36%), Positives = 71/122 (58%), Gaps = 3/122 (2%) Frame = +3 Query: 2130 RSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQ 2309 R+ + GT EYLAPE+I+ GHG AVDWW G+ ++E+L G PF +++ Sbjct: 200 RTWTLCGTPEYLAPEVIQSKGHGRAVDWWALGILIFEMLSGFPPFFDDNPFGIYQKILAG 259 Query: 2310 NLRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLR-GAAEIKQHPFFEGLNWALI--RSVA 2480 + FP + + + KDLI+ LLV + RLG ++ GA ++K H +F ++W + R + Sbjct: 260 KIDFPRH--LDFHVKDLIKKLLVVDRTRRLGNMKNGANDVKHHRWFRSVDWEAVPQRKLK 317 Query: 2481 PP 2486 PP Sbjct: 318 PP 319
>Q3U214:MAST3_MOUSE Microtubule-associated serine/threonine-protein kinase 3 - Mus| musculus (Mouse) Length = 1321 Score = 108 bits (269), Expect = 2e-22 Identities = 58/146 (39%), Positives = 85/146 (58%) Frame = +3 Query: 1449 NFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEMLDHP 1628 +F +K + G G VYL D+ FA+K ++ + LI R ++ + ER+IL ++P Sbjct: 388 DFETIKLISNGAYGAVYLVRHRDTRQRFAIKKINKQNLILRNQIQQVFVERDILTFAENP 447 Query: 1629 FLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALEYLHM 1808 F+ ++ F T C+VMEY GGD L + P AR Y AE +LALEYLH Sbjct: 448 FVVGMFCSFETRRHLCMVMEYVEGGDCATLLKNMG--PLPVDMARMYFAETVLALEYLHN 505 Query: 1809 LGVIYRDLKPENILVRDDGHIMLSDF 1886 G+++RDLKP+N+L+ GHI L+DF Sbjct: 506 YGIVHRDLKPDNLLITSLGHIKLTDF 531 Score = 99.0 bits (245), Expect = 1e-19 Identities = 51/106 (48%), Positives = 66/106 (62%), Gaps = 1/106 (0%) Frame = +3 Query: 2148 GTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQNLRFPD 2327 GT EY+APE+I G+G VDWW GV LYE L G PF G +E VVS + +P+ Sbjct: 564 GTPEYIAPEVIFRQGYGKPVDWWAMGVILYEFLVGCVPFFGDTPEELFGQVVSDEIMWPE 623 Query: 2328 -NPVVSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPFFEGLNWA 2462 + + +A+DLI LL + P +RLGT G E+KQHPFF L+WA Sbjct: 624 GDEALPLDAQDLITRLLRQSPMDRLGT-GGTHEVKQHPFFLALDWA 668
>O19111:KPCZ_RABIT Protein kinase C zeta type - Oryctolagus cuniculus (Rabbit)| Length = 591 Score = 108 bits (269), Expect = 2e-22 Identities = 64/158 (40%), Positives = 94/158 (59%), Gaps = 1/158 (0%) Frame = +3 Query: 1416 LALQQGPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQA 1595 + + QG LGL +F L++ +G G V L L + ++A+KV+ E + + + Q Sbjct: 240 IKISQG-LGLQDFDLIRVIGRGSYAKVLLVRLKKNGQVYAMKVVKKELVHDDEDIDWVQT 298 Query: 1596 EREILEMLD-HPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYV 1772 E+ + E +PFL L++ F T + LV+EY GGDL QRQ R PE ARFY Sbjct: 299 EKHVFEQASGNPFLVGLHSCFQTTSRLFLVIEYVNGGDLMFHMQRQ--RKLPEEHARFYA 356 Query: 1773 AEVLLALEYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 AE+ +AL +LH G+IYRDLK +N+L+ DGHI L+D+ Sbjct: 357 AEICIALNFLHERGIIYRDLKLDNVLLDADGHIKLTDY 394 Score = 82.8 bits (203), Expect = 7e-15 Identities = 44/129 (34%), Positives = 74/129 (57%), Gaps = 11/129 (8%) Frame = +3 Query: 2133 SNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPF----RGPG---NDETL 2291 +++F GT Y+APEI++G+ +G +VDWW GV ++E++ GR+PF P D Sbjct: 407 TSTFCGTPNYIAPEILRGEEYGFSVDWWALGVLMFEMMAGRSPFDIITDNPDMNTEDYLF 466 Query: 2292 ANVVSQNLRFPDNPVVSSNAKDLIRGLLVKEPENRLG--TLRGAAEIKQHPFFEGLNWAL 2465 ++ + +R P +S A +++G L K+P+ RLG G ++IK H FF ++W L Sbjct: 467 QVILEKPIRIP--RFLSVKASHVLKGFLNKDPKERLGCRPQTGFSDIKSHAFFRSIDWDL 524 Query: 2466 I--RSVAPP 2486 + + PP Sbjct: 525 LEKKQALPP 533
>Q5VT25:MRCKA_HUMAN Serine/threonine-protein kinase MRCK alpha - Homo sapiens (Human)| Length = 1732 Score = 107 bits (267), Expect = 3e-22 Identities = 63/179 (35%), Positives = 108/179 (60%), Gaps = 5/179 (2%) Frame = +3 Query: 1365 NNRP-----HMVKDLCWITIRQLALQQGPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCL 1529 NN P ++++ L W ++Q L ++F +LK +G G G V + +L ++D + Sbjct: 43 NNSPLRREKNILEYLEWAKPFTSKVKQMRLHREDFEILKVIGRGAFGEVAVVKLKNADKV 102 Query: 1530 FALKVMDIEYLISRKKMLRAQAEREILEMLDHPFLPTLYAHFTTDNLSCLVMEYCPGGDL 1709 FA+K+++ ++ R + + ER++L D+ ++ TL+ F DN LVM+Y GGDL Sbjct: 103 FAMKILNKWEMLKRAETACFREERDVLVNGDNKWITTLHYAFQDDNNLYLVMDYYVGGDL 162 Query: 1710 HVLRQRQPGRSFPEPSARFYVAEVLLALEYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 L + R PE ARFY+AE+++A++ +H L ++RD+KP+NIL+ +GHI L+DF Sbjct: 163 LTLLSKFEDR-LPEDMARFYLAEMVIAIDSVHQLHYVHRDIKPDNILMDMNGHIRLADF 220 Score = 92.4 bits (228), Expect = 9e-18 Identities = 54/134 (40%), Positives = 79/134 (58%), Gaps = 8/134 (5%) Frame = +3 Query: 2109 VVEPTEARSNSFVGTHEYLAPEIIKG--DG---HGSAVDWWTFGVFLYELLYGRTPFRGP 2273 ++E +S+ VGT +Y++PEI++ DG +G DWW+ GV +YE+LYG TPF Sbjct: 226 LMEDGTVQSSVAVGTPDYISPEILQAMEDGKGRYGPECDWWSLGVCMYEMLYGETPFYAE 285 Query: 2274 GNDETLANVVS--QNLRFPDNPV-VSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPFF 2444 ET +++ + +FP VS NAKDLIR L+ E+RLG G + K+HPFF Sbjct: 286 SLVETYGKIMNHKERFQFPAQVTDVSENAKDLIRRLICSR-EHRLGQ-NGIEDFKKHPFF 343 Query: 2445 EGLNWALIRSVAPP 2486 G++W IR+ P Sbjct: 344 SGIDWDNIRNCEAP 357
>Q9UK32:KS6A6_HUMAN Ribosomal protein S6 kinase alpha-6 - Homo sapiens (Human)| Length = 745 Score = 107 bits (267), Expect = 3e-22 Identities = 61/148 (41%), Positives = 92/148 (62%), Gaps = 3/148 (2%) Frame = +3 Query: 1452 FRLLKRLGCGDIGTVYLAELV---DSDCLFALKVMDIEYLISRKKMLRAQAEREILEMLD 1622 F LLK LG G G V+L D+ L+A+KV+ L R ++ R + ER+IL ++ Sbjct: 73 FELLKVLGQGSFGKVFLVRKKTGPDAGQLYAMKVLKKASLKVRDRV-RTKMERDILVEVN 131 Query: 1623 HPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALEYL 1802 HPF+ L+ F T+ L++++ GGD+ ++ F E +FY+AE+ LAL++L Sbjct: 132 HPFIVKLHYAFQTEGKLYLILDFLRGGDVFTRLSKEV--LFTEEDVKFYLAELALALDHL 189 Query: 1803 HMLGVIYRDLKPENILVRDDGHIMLSDF 1886 H LG++YRDLKPENIL+ + GHI L+DF Sbjct: 190 HQLGIVYRDLKPENILLDEIGHIKLTDF 217 Score = 100 bits (250), Expect = 3e-20 Identities = 49/123 (39%), Positives = 75/123 (60%), Gaps = 2/123 (1%) Frame = +3 Query: 2124 EARSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVV 2303 E ++ SF GT EY+APE++ GH + DWW++GV ++E+L G PF+G +ET+ ++ Sbjct: 227 EKKAYSFCGTVEYMAPEVVNRRGHSQSADWWSYGVLMFEMLTGTLPFQGKDRNETMNMIL 286 Query: 2304 SQNLRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPFFEGLNWALI--RSV 2477 L P +S+ A+ L+R L + P NRLG+ G EIK+H FF ++W + R V Sbjct: 287 KAKLGMPQ--FLSAEAQSLLRMLFKRNPANRLGS-EGVEEIKRHLFFANIDWDKLYKREV 343 Query: 2478 APP 2486 PP Sbjct: 344 QPP 346 Score = 48.9 bits (115), Expect = 1e-04 Identities = 38/116 (32%), Positives = 53/116 (45%), Gaps = 3/116 (2%) Frame = +3 Query: 1524 CLFALKVMDIEYLISRKKMLRAQAEREILEML-DHPFLPTLYAHFTTDNLSCLVMEYCPG 1700 C+ A M+ I K E EIL HP + TL F LV + G Sbjct: 443 CIHATTNMEFAVKIIDKSKRDPSEEIEILMRYGQHPNIITLKDVFDDGRYVYLVTDLMKG 502 Query: 1701 GDL--HVLRQRQPGRSFPEPSARFYVAEVLLALEYLHMLGVIYRDLKPENILVRDD 1862 G+L +L+Q+ F E A + + ++YLH GV++RDLKP NIL D+ Sbjct: 503 GELLDRILKQK----CFSEREASDILYVISKTVDYLHCQGVVHRDLKPSNILYMDE 554 Score = 48.9 bits (115), Expect = 1e-04 Identities = 30/89 (33%), Positives = 44/89 (49%), Gaps = 7/89 (7%) Frame = +3 Query: 2151 THEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGND---ETLANVVSQNLRF 2321 T ++APE++ G+ +A D W+ GV Y +L G TPF ND E L + + Sbjct: 585 TANFVAPEVLMQQGYDAACDIWSLGVLFYTMLAGYTPFANGPNDTPEEILLRIGNGKFSL 644 Query: 2322 P----DNPVVSSNAKDLIRGLLVKEPENR 2396 DN +S AKDL+ +L +P R Sbjct: 645 SGGNWDN--ISDGAKDLLSHMLHMDPHQR 671
>Q9Y2H1:ST38L_HUMAN Serine/threonine-protein kinase 38-like - Homo sapiens (Human)| Length = 464 Score = 107 bits (266), Expect = 4e-22 Identities = 54/157 (34%), Positives = 96/157 (61%) Frame = +3 Query: 1416 LALQQGPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQA 1595 L L++ LGLD+F LK +G G G V L + D+ ++A+K++ ++ ++++ +A Sbjct: 78 LRLKRTRLGLDDFESLKVIGRGAFGEVRLVQKKDTGHIYAMKILRKSDMLEKEQVAHIRA 137 Query: 1596 EREILEMLDHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVA 1775 ER+IL D ++ ++ F L+ME+ PGGD+ L ++ + E +FY++ Sbjct: 138 ERDILVEADGAWVVKMFYSFQDKRNLYLIMEFLPGGDMMTLLMKKD--TLTEEETQFYIS 195 Query: 1776 EVLLALEYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 E +LA++ +H LG I+RD+KP+N+L+ GH+ LSDF Sbjct: 196 ETVLAIDAIHQLGFIHRDIKPDNLLLDAKGHVKLSDF 232 Score = 91.7 bits (226), Expect = 2e-17 Identities = 49/113 (43%), Positives = 65/113 (57%), Gaps = 2/113 (1%) Frame = +3 Query: 2139 SFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVS--QN 2312 S VGT +Y+APE+ G+ DWW+ GV +YE+L G PF ET V++ + Sbjct: 282 STVGTPDYIAPEVFMQTGYNKLCDWWSLGVIMYEMLIGYPPFCSETPQETYRKVMNWKET 341 Query: 2313 LRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPFFEGLNWALIR 2471 L FP +S AKDLI + + ENR+G G EIK HPFFEG++W IR Sbjct: 342 LVFPPEVPISEKAKDLILRFCI-DSENRIGN-SGVEEIKGHPFFEGVDWEHIR 392
>P50530:SCK1_SCHPO Serine/threonine-protein kinase sck1 - Schizosaccharomyces pombe| (Fission yeast) Length = 696 Score = 107 bits (266), Expect = 4e-22 Identities = 62/152 (40%), Positives = 93/152 (61%), Gaps = 3/152 (1%) Frame = +3 Query: 1440 GLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREIL--- 1610 G ++F L+ +G G G VYL D++ ++A+K + + ++ +K++ ER IL Sbjct: 298 GPEDFTALRLIGKGTFGQVYLVRKNDTNRIYAMKKISKKLIVRKKEVTHTLGERNILVRT 357 Query: 1611 EMLDHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLA 1790 + + PF+ L F T + L+ +Y GG+L Q + GR FPE A+FY+AE++LA Sbjct: 358 SLDESPFIVGLKFSFQTASDLYLITDYMSGGELFWHLQHE-GR-FPEQRAKFYIAELVLA 415 Query: 1791 LEYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 LE+LH +IYRDLKPENIL+ DGHI L DF Sbjct: 416 LEHLHKHDIIYRDLKPENILLDADGHIALCDF 447 Score = 101 bits (252), Expect = 1e-20 Identities = 50/123 (40%), Positives = 75/123 (60%), Gaps = 3/123 (2%) Frame = +3 Query: 2127 ARSNSFVGTHEYLAPEIIKGD-GHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVV 2303 A +N+F GT EYLAPE++ D G+ VD+W+ GV ++E+ G +PF P + N+ Sbjct: 458 ATTNTFCGTTEYLAPEVLLEDKGYTKQVDFWSLGVLVFEMCCGWSPFYAPDVQQMYRNIA 517 Query: 2304 SQNLRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPFFEGLNWALI--RSV 2477 +RFP V+SS + +RGLL + P +RLG + E+K+HPFF +NW L+ + V Sbjct: 518 FGKVRFPKG-VLSSEGRSFVRGLLNRNPNHRLGAVADTTELKEHPFFADINWDLLSKKKV 576 Query: 2478 APP 2486 PP Sbjct: 577 QPP 579
>Q12706:PSK1_SCHPO Serine/threonine-protein kinase psk1 - Schizosaccharomyces pombe| (Fission yeast) Length = 436 Score = 107 bits (266), Expect = 4e-22 Identities = 63/149 (42%), Positives = 90/149 (60%), Gaps = 3/149 (2%) Frame = +3 Query: 1449 NFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKML-RAQAEREILEMLDH 1625 +F+ L LG G G V L + ++ LFA K + ++ R K L + + ER+ILE + H Sbjct: 90 DFQPLTVLGRGSYGKVLLVKQKNTGRLFAQKQLKKASIVLRAKGLEQTKNERQILEEVRH 149 Query: 1626 PFLPTLYAHFTTDNLSCLVMEYCPGGDL--HVLRQRQPGRSFPEPSARFYVAEVLLALEY 1799 PF+ LY F + L+++Y PGG+L H+ QR PE FY AE+ LAL + Sbjct: 150 PFICRLYYAFQDHDRLYLILQYAPGGELFSHLAEQRM----LPEDVVAFYTAELTLALIH 205 Query: 1800 LHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 LH LG++YRDLKPEN L+ +GHI+L+DF Sbjct: 206 LHKLGIVYRDLKPENCLLDAEGHILLTDF 234 Score = 82.0 bits (201), Expect = 1e-14 Identities = 45/129 (34%), Positives = 67/129 (51%), Gaps = 4/129 (3%) Frame = +3 Query: 2127 ARSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVS 2306 A SFVGT EY APEI+ + AVDWW+ G+ +++LL G PF + + + Sbjct: 244 ADCRSFVGTEEYCAPEILLEQPYDHAVDWWSMGILIFDLLTGSPPFTANNHKRIMEKITR 303 Query: 2307 QNLRFPDNPVVSSNAKDLIRGLLVKEPENRLGT---LRGAAEIKQHPFFEGLNW-ALIRS 2474 P V+S+A+D+I L K P+ RLG +G IK+H + ++W L + Sbjct: 304 AKPNIPF--YVTSDARDIINKFLKKNPKQRLGADGPEKGYDAIKKHRIYRRIDWNKLEKR 361 Query: 2475 VAPPETRPC 2501 + PP PC Sbjct: 362 MLPPPIVPC 370
>Q60592:MAST2_MOUSE Microtubule-associated serine/threonine-protein kinase 2 - Mus| musculus (Mouse) Length = 1734 Score = 107 bits (266), Expect = 4e-22 Identities = 56/147 (38%), Positives = 87/147 (59%) Frame = +3 Query: 1446 DNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEMLDH 1625 ++F +K + G G V+L + FA+K ++ + LI R ++ +A ER+IL ++ Sbjct: 451 EDFETIKLISNGAYGAVFLVRHKSTRQRFAMKKINKQNLILRNQIQQAFVERDILTFAEN 510 Query: 1626 PFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALEYLH 1805 PF+ +++ F T C+VMEY GGD L + + P R Y AE +LALEYLH Sbjct: 511 PFVVSMFCSFETKRHLCMVMEYVEGGDCATLLKNIG--ALPVDMVRLYFAETVLALEYLH 568 Query: 1806 MLGVIYRDLKPENILVRDDGHIMLSDF 1886 G+++RDLKP+N+L+ GHI L+DF Sbjct: 569 NYGIVHRDLKPDNLLITSMGHIKLTDF 595 Score = 96.7 bits (239), Expect = 5e-19 Identities = 51/113 (45%), Positives = 68/113 (60%), Gaps = 2/113 (1%) Frame = +3 Query: 2148 GTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQNLRFPD 2327 GT EY+APE+I G+G VDWW G+ LYE L G PF G +E V+S + +P+ Sbjct: 628 GTPEYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDEIVWPE 687 Query: 2328 -NPVVSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPFFEGLNW-ALIRSVA 2480 + + +A+DL LL + P RLGT A E+KQHPFF GL+W L+R A Sbjct: 688 GDDALPPDAQDLTSKLLHQNPLERLGT-SSAYEVKQHPFFMGLDWTGLLRQKA 739
>Q6P0Q8:MAST2_HUMAN Microtubule-associated serine/threonine-protein kinase 2 - Homo| sapiens (Human) Length = 1798 Score = 107 bits (266), Expect = 4e-22 Identities = 56/147 (38%), Positives = 87/147 (59%) Frame = +3 Query: 1446 DNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEMLDH 1625 ++F +K + G G V+L + FA+K ++ + LI R ++ +A ER+IL ++ Sbjct: 510 EDFETIKLISNGAYGAVFLVRHKSTRQRFAMKKINKQNLILRNQIQQAFVERDILTFAEN 569 Query: 1626 PFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALEYLH 1805 PF+ +++ F T C+VMEY GGD L + + P R Y AE +LALEYLH Sbjct: 570 PFVVSMFCSFDTKRHLCMVMEYVEGGDCATLLKNIG--ALPVDMVRLYFAETVLALEYLH 627 Query: 1806 MLGVIYRDLKPENILVRDDGHIMLSDF 1886 G+++RDLKP+N+L+ GHI L+DF Sbjct: 628 NYGIVHRDLKPDNLLITSMGHIKLTDF 654 Score = 96.7 bits (239), Expect = 5e-19 Identities = 51/113 (45%), Positives = 68/113 (60%), Gaps = 2/113 (1%) Frame = +3 Query: 2148 GTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQNLRFPD 2327 GT EY+APE+I G+G VDWW G+ LYE L G PF G +E V+S + +P+ Sbjct: 687 GTPEYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDEIVWPE 746 Query: 2328 -NPVVSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPFFEGLNW-ALIRSVA 2480 + + +A+DL LL + P RLGT A E+KQHPFF GL+W L+R A Sbjct: 747 GDEALPPDAQDLTSKLLHQNPLERLGT-GSAYEVKQHPFFTGLDWTGLLRQKA 798
>O43930:PRKY_HUMAN Serine/threonine-protein kinase PRKY - Homo sapiens (Human)| Length = 277 Score = 106 bits (265), Expect = 5e-22 Identities = 60/143 (41%), Positives = 84/143 (58%), Gaps = 1/143 (0%) Frame = +3 Query: 1461 LKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEMLDHPFLPT 1640 L +G G G V+L + + FALKVM I +I RK+ E+ +L+ + HPFL Sbjct: 52 LVTMGTGTFGRVHLVKEKTAKHFFALKVMSIPDVIRRKQEQHVHNEKSVLKEVSHPFLIR 111 Query: 1641 LYAHFTTDNLSCLVMEYCPGGDLH-VLRQRQPGRSFPEPSARFYVAEVLLALEYLHMLGV 1817 L+ + + ++MEY PGG+L LR R F + FY AE++ A+EYLH + Sbjct: 112 LFWTWHEERFLYMLMEYVPGGELFSYLRNRG---HFSSTTGLFYSAEIICAIEYLHSKEI 168 Query: 1818 IYRDLKPENILVRDDGHIMLSDF 1886 +YRDLKPENIL+ DGHI L+DF Sbjct: 169 VYRDLKPENILLDRDGHIKLTDF 191 Score = 60.8 bits (146), Expect = 3e-08 Identities = 27/65 (41%), Positives = 38/65 (58%) Frame = +3 Query: 2130 RSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQ 2309 R+ + GT EYLAPE+I+ GHG AVDWW G+ ++E+L G PF +++ Sbjct: 200 RTWTLCGTPEYLAPEVIQSKGHGRAVDWWALGILIFEMLSGFPPFFDDNPFGIYQKILAG 259 Query: 2310 NLRFP 2324 L FP Sbjct: 260 KLYFP 264
>O13310:ORB6_SCHPO Serine/threonine-protein kinase orb6 - Schizosaccharomyces pombe| (Fission yeast) Length = 469 Score = 106 bits (265), Expect = 5e-22 Identities = 58/157 (36%), Positives = 93/157 (59%) Frame = +3 Query: 1416 LALQQGPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQA 1595 L ++ L L++F +K +G G G V L + +D+ ++A+K + + R ++ +A Sbjct: 81 LRFRRTRLSLEDFSTIKVIGKGAFGEVRLVQKLDTGKIYAMKSLLKTEMFKRDQLAHVKA 140 Query: 1596 EREILEMLDHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVA 1775 ER++L D P++ +LY F L+ME+ PGGDL + +F E RFY+A Sbjct: 141 ERDLLVESDSPWVVSLYYAFQDSLYLYLIMEFLPGGDLMTMLINYD--TFSEDVTRFYMA 198 Query: 1776 EVLLALEYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 E +LA+ +H +G I+RD+KP+NIL+ DGHI LSDF Sbjct: 199 ECVLAIADVHRMGYIHRDIKPDNILIDRDGHIKLSDF 235 Score = 91.7 bits (226), Expect = 2e-17 Identities = 49/118 (41%), Positives = 70/118 (59%), Gaps = 2/118 (1%) Frame = +3 Query: 2139 SFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVS--QN 2312 S VGT +Y+APEI G+G DWW+ G ++E L G PF + ET +++ + Sbjct: 291 STVGTPDYIAPEIFLQQGYGQDCDWWSLGAIMFECLIGWPPFCSENSHETYRKIINWRET 350 Query: 2313 LRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPFFEGLNWALIRSVAPP 2486 L FP++ +S A+DL+ L+ + E+RLG GA EI QHPFF G++W IR A P Sbjct: 351 LTFPNDIHLSIEARDLMDRLMT-DSEHRLGR-GGAIEIMQHPFFTGIDWDHIRETAAP 406
>O54874:MRCKA_RAT Serine/threonine-protein kinase MRCK alpha - Rattus norvegicus (Rat)| Length = 1732 Score = 106 bits (265), Expect = 5e-22 Identities = 63/179 (35%), Positives = 107/179 (59%), Gaps = 5/179 (2%) Frame = +3 Query: 1365 NNRP-----HMVKDLCWITIRQLALQQGPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCL 1529 NN P ++++ L W ++Q L ++F +LK +G G G V + +L ++D + Sbjct: 43 NNSPLRREKNILEYLEWAKPFTSKVKQMRLHREDFEILKVIGRGAFGEVAVVKLKNADKV 102 Query: 1530 FALKVMDIEYLISRKKMLRAQAEREILEMLDHPFLPTLYAHFTTDNLSCLVMEYCPGGDL 1709 FA+K+++ ++ R + + ER++L D ++ TL+ F DN LVM+Y GGDL Sbjct: 103 FAMKILNKWEMLKRAETACFREERDVLVNGDSKWITTLHYAFQDDNNLYLVMDYYVGGDL 162 Query: 1710 HVLRQRQPGRSFPEPSARFYVAEVLLALEYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 L + R PE ARFY+AE+++A++ +H L ++RD+KP+NIL+ +GHI L+DF Sbjct: 163 LTLLSKFEDR-LPEEMARFYLAEMVIAIDSVHQLHYVHRDIKPDNILMDMNGHIRLADF 220 Score = 92.8 bits (229), Expect = 7e-18 Identities = 54/134 (40%), Positives = 79/134 (58%), Gaps = 8/134 (5%) Frame = +3 Query: 2109 VVEPTEARSNSFVGTHEYLAPEIIKG--DG---HGSAVDWWTFGVFLYELLYGRTPFRGP 2273 ++E +S+ VGT +Y++PEI++ DG +G DWW+ GV +YE+LYG TPF Sbjct: 226 LMEDGTVQSSVAVGTPDYISPEILQAMEDGKGRYGPECDWWSLGVCMYEMLYGETPFYAE 285 Query: 2274 GNDETLANVVS--QNLRFPDNPV-VSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPFF 2444 ET +++ + +FP VS NAKDLIR L+ E+RLG G + K+HPFF Sbjct: 286 SLVETYGKIMNHKERFQFPTQVTDVSENAKDLIRRLICSR-EHRLGQ-NGIEDFKKHPFF 343 Query: 2445 EGLNWALIRSVAPP 2486 G++W IR+ P Sbjct: 344 SGIDWDNIRNCEAP 357
>Q3UU96:MRCKA_MOUSE Serine/threonine-protein kinase MRCK alpha - Mus musculus (Mouse)| Length = 1719 Score = 106 bits (265), Expect = 5e-22 Identities = 63/179 (35%), Positives = 107/179 (59%), Gaps = 5/179 (2%) Frame = +3 Query: 1365 NNRP-----HMVKDLCWITIRQLALQQGPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCL 1529 NN P ++++ L W ++Q L ++F +LK +G G G V + +L ++D + Sbjct: 43 NNSPLRREKNILEYLEWAKPFTSKVKQMRLHREDFEILKVIGRGAFGEVAVVKLKNADKV 102 Query: 1530 FALKVMDIEYLISRKKMLRAQAEREILEMLDHPFLPTLYAHFTTDNLSCLVMEYCPGGDL 1709 FA+K+++ ++ R + + ER++L D ++ TL+ F DN LVM+Y GGDL Sbjct: 103 FAMKILNKWEMLKRAETACFREERDVLVNGDSKWITTLHYAFQDDNNLYLVMDYYVGGDL 162 Query: 1710 HVLRQRQPGRSFPEPSARFYVAEVLLALEYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 L + R PE ARFY+AE+++A++ +H L ++RD+KP+NIL+ +GHI L+DF Sbjct: 163 LTLLSKFEDR-LPEEMARFYLAEMVIAIDSVHQLHYVHRDIKPDNILMDMNGHIRLADF 220 Score = 92.4 bits (228), Expect = 9e-18 Identities = 54/134 (40%), Positives = 79/134 (58%), Gaps = 8/134 (5%) Frame = +3 Query: 2109 VVEPTEARSNSFVGTHEYLAPEIIKG--DG---HGSAVDWWTFGVFLYELLYGRTPFRGP 2273 ++E +S+ VGT +Y++PEI++ DG +G DWW+ GV +YE+LYG TPF Sbjct: 226 LMEDGTVQSSVAVGTPDYISPEILQAMEDGKGRYGPECDWWSLGVCMYEMLYGETPFYAE 285 Query: 2274 GNDETLANVVS--QNLRFPDNPV-VSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPFF 2444 ET +++ + +FP VS NAKDLIR L+ E+RLG G + K+HPFF Sbjct: 286 SLVETYGKIMNHKERFQFPAQVTDVSENAKDLIRRLICSR-EHRLGQ-NGIEDFKKHPFF 343 Query: 2445 EGLNWALIRSVAPP 2486 G++W IR+ P Sbjct: 344 SGIDWDNIRNCEAP 357
>Q6AX33:MAST3_XENLA Microtubule-associated serine/threonine-protein kinase 3 - Xenopus| laevis (African clawed frog) Length = 1482 Score = 106 bits (265), Expect = 5e-22 Identities = 56/146 (38%), Positives = 86/146 (58%) Frame = +3 Query: 1449 NFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEMLDHP 1628 +F +K + G G VYL ++ FA+K ++ + LI R ++ + ER+IL ++P Sbjct: 398 DFETIKLISNGAYGAVYLVRHKETRQRFAMKKINKQNLILRNQIHQVFVERDILTFAENP 457 Query: 1629 FLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALEYLHM 1808 F+ +++ F T C+VMEY GGD L + P +R Y AE +LALEYLH Sbjct: 458 FVVSMFCSFETRRHLCMVMEYVEGGDCATLLKNMG--PLPVDMSRMYFAETVLALEYLHN 515 Query: 1809 LGVIYRDLKPENILVRDDGHIMLSDF 1886 G+++RDLKP+N+L+ GHI L+DF Sbjct: 516 YGIVHRDLKPDNLLITSLGHIKLTDF 541 Score = 90.5 bits (223), Expect = 3e-17 Identities = 49/113 (43%), Positives = 67/113 (59%), Gaps = 2/113 (1%) Frame = +3 Query: 2148 GTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQNLRFP- 2324 GT EY+APE+I G+G VDWW G+ LYE L G PF G +E V+S ++ +P Sbjct: 574 GTPEYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDDIIWPG 633 Query: 2325 DNPVVSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPFFEGLNW-ALIRSVA 2480 + ++++DLI LL + RLGT GA E+KQH FF L+W L+R A Sbjct: 634 GEEALPADSQDLITRLLRQNSLERLGT-GGAQEVKQHTFFLSLDWNGLLRQKA 685
>Q19266:KPC3_CAEEL Protein kinase C-like 3 - Caenorhabditis elegans| Length = 597 Score = 106 bits (265), Expect = 5e-22 Identities = 59/151 (39%), Positives = 92/151 (60%), Gaps = 1/151 (0%) Frame = +3 Query: 1437 LGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEM 1616 + L++FRLL +G G V AE V + ++A+K++ E + + Q E+ + E Sbjct: 248 VSLNDFRLLTVIGRGSYAKVVQAEHVSTRQIYAIKIIKKEMFNEDEDIDWVQTEKSVFEA 307 Query: 1617 L-DHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLAL 1793 ++PFL L++ F T++ V+E+ PGGDL Q+Q R PE ARFY E++LAL Sbjct: 308 ASNYPFLVGLHSCFQTESRLFFVIEFVPGGDLMFHMQQQ--RKLPEEHARFYSGEIILAL 365 Query: 1794 EYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 +LH G+IYRDLK +N+L+ +GHI L+D+ Sbjct: 366 HFLHSRGIIYRDLKLDNVLIDAEGHIKLTDY 396 Score = 86.7 bits (213), Expect = 5e-16 Identities = 46/133 (34%), Positives = 78/133 (58%), Gaps = 15/133 (11%) Frame = +3 Query: 2133 SNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLAN----- 2297 +++F GT Y+APEI++GD +G +VDWW GV ++E++ GR+PF G + N Sbjct: 409 TSTFCGTPNYIAPEILRGDEYGFSVDWWALGVLMFEMMAGRSPFDIVGMQNSEENTEDYL 468 Query: 2298 ---VVSQNLRFPDNPVVSSNAKDLIRGLLVKEPENRLGTL----RGAAEIKQHPFFEG-L 2453 ++ + +R P + +S A +++G L K+P RLG G ++K+H FF G + Sbjct: 469 FQIILERQIRIPRS--LSVRASGILKGFLNKDPTERLGCKLDINEGLRDMKEHQFFRGFI 526 Query: 2454 NWALI--RSVAPP 2486 +W + ++VAPP Sbjct: 527 DWEALEQKAVAPP 539
>Q61410:KGP2_MOUSE cGMP-dependent protein kinase 2 - Mus musculus (Mouse)| Length = 762 Score = 106 bits (265), Expect = 5e-22 Identities = 57/147 (38%), Positives = 90/147 (61%), Gaps = 1/147 (0%) Frame = +3 Query: 1449 NFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEMLDHP 1628 N ++ LG G G V L ++ + + FA+K + ++++ K+ +E+ ILE L P Sbjct: 452 NLEIIATLGVGGFGRVELVKVKNENVAFAMKCIRKKHIVDTKQQEHVYSEKRILEELCSP 511 Query: 1629 FLPTLYAHFTTDNLSCLVMEYCPGGDL-HVLRQRQPGRSFPEPSARFYVAEVLLALEYLH 1805 F+ LY F + +++E C GG+L +LR R SF EP+++F VA V A +YLH Sbjct: 512 FIVKLYRTFKDNKYVYMLLEACLGGELWSILRDRG---SFDEPTSKFCVACVTEAFDYLH 568 Query: 1806 MLGVIYRDLKPENILVRDDGHIMLSDF 1886 +LG+IYRDLKPEN+++ DG++ L DF Sbjct: 569 LLGIIYRDLKPENLILDADGYLKLVDF 595 Score = 82.4 bits (202), Expect = 9e-15 Identities = 45/118 (38%), Positives = 69/118 (58%), Gaps = 2/118 (1%) Frame = +3 Query: 2139 SFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQNLR 2318 +F GT EY+APE+I GH +VD+W+ G+ +YELL G PF G T N++ + + Sbjct: 609 TFCGTPEYVAPEVILNKGHDFSVDFWSLGILVYELLTGNPPFSGIDQMMTY-NLILKGIE 667 Query: 2319 FPDNP-VVSSNAKDLIRGLLVKEPENRLGTLR-GAAEIKQHPFFEGLNWALIRSVAPP 2486 D P ++ +DLIR L + P RLG L+ G +IK+H + G NW +++ + P Sbjct: 668 KMDFPRKITRRPEDLIRRLCRQNPTERLGNLKNGINDIKKHRWLNGFNWEGLKARSLP 725
>Q63484:AKT3_RAT RAC-gamma serine/threonine-protein kinase - Rattus norvegicus (Rat)| Length = 479 Score = 106 bits (265), Expect = 5e-22 Identities = 58/148 (39%), Positives = 86/148 (58%) Frame = +3 Query: 1443 LDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEMLD 1622 +++F LK LG G G V L S +A+K++ E +I++ ++ E +L+ Sbjct: 145 MNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTR 204 Query: 1623 HPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALEYL 1802 HPFL +L F T + C VMEY GG+L R+ R F E RFY AE++ AL+YL Sbjct: 205 HPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRE--RVFSEDRTRFYGAEIVSALDYL 262 Query: 1803 HMLGVIYRDLKPENILVRDDGHIMLSDF 1886 H ++YRDLK EN+++ DGHI ++DF Sbjct: 263 HSGKIVYRDLKLENLMLDKDGHIKITDF 290 Score = 100 bits (248), Expect = 4e-20 Identities = 49/123 (39%), Positives = 77/123 (62%), Gaps = 3/123 (2%) Frame = +3 Query: 2127 ARSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVS 2306 A +F GT EYLAPE+++ + +G AVDWW GV +YE++ GR PF +++ ++ Sbjct: 301 ATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILM 360 Query: 2307 QNLRFPDNPVVSSNAKDLIRGLLVKEPENRL-GTLRGAAEIKQHPFFEGLNWALI--RSV 2477 ++++FP +SS+AK L+ GLL+K+P RL G EI +H FF G+NW + + + Sbjct: 361 EDIKFP--RTLSSDAKSLLSGLLIKDPNKRLGGGPDDPKEIMRHSFFSGVNWQDVYDKKL 418 Query: 2478 APP 2486 PP Sbjct: 419 VPP 421
>Q9WUA6:AKT3_MOUSE RAC-gamma serine/threonine-protein kinase - Mus musculus (Mouse)| Length = 479 Score = 106 bits (265), Expect = 5e-22 Identities = 58/148 (39%), Positives = 86/148 (58%) Frame = +3 Query: 1443 LDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEMLD 1622 +++F LK LG G G V L S +A+K++ E +I++ ++ E +L+ Sbjct: 145 MNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTR 204 Query: 1623 HPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALEYL 1802 HPFL +L F T + C VMEY GG+L R+ R F E RFY AE++ AL+YL Sbjct: 205 HPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRE--RVFSEDRTRFYGAEIVSALDYL 262 Query: 1803 HMLGVIYRDLKPENILVRDDGHIMLSDF 1886 H ++YRDLK EN+++ DGHI ++DF Sbjct: 263 HSGKIVYRDLKLENLMLDKDGHIKITDF 290 Score = 102 bits (253), Expect = 1e-20 Identities = 50/123 (40%), Positives = 78/123 (63%), Gaps = 3/123 (2%) Frame = +3 Query: 2127 ARSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVS 2306 A +F GT EYLAPE+++ + +G AVDWW GV +YE++ GR PF +++ ++ Sbjct: 301 ATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILM 360 Query: 2307 QNLRFPDNPVVSSNAKDLIRGLLVKEPENRL-GTLRGAAEIKQHPFFEGLNWALI--RSV 2477 ++++FP +SS+AK L+ GLL+K+P RL G A EI +H FF G+NW + + + Sbjct: 361 EDIKFP--RTLSSDAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFSGVNWQDVYDKKL 418 Query: 2478 APP 2486 PP Sbjct: 419 VPP 421
>Q9Y243:AKT3_HUMAN RAC-gamma serine/threonine-protein kinase - Homo sapiens (Human)| Length = 479 Score = 106 bits (265), Expect = 5e-22 Identities = 58/148 (39%), Positives = 86/148 (58%) Frame = +3 Query: 1443 LDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEMLD 1622 +++F LK LG G G V L S +A+K++ E +I++ ++ E +L+ Sbjct: 145 MNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTR 204 Query: 1623 HPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALEYL 1802 HPFL +L F T + C VMEY GG+L R+ R F E RFY AE++ AL+YL Sbjct: 205 HPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRE--RVFSEDRTRFYGAEIVSALDYL 262 Query: 1803 HMLGVIYRDLKPENILVRDDGHIMLSDF 1886 H ++YRDLK EN+++ DGHI ++DF Sbjct: 263 HSGKIVYRDLKLENLMLDKDGHIKITDF 290 Score = 102 bits (253), Expect = 1e-20 Identities = 50/123 (40%), Positives = 78/123 (63%), Gaps = 3/123 (2%) Frame = +3 Query: 2127 ARSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVS 2306 A +F GT EYLAPE+++ + +G AVDWW GV +YE++ GR PF +++ ++ Sbjct: 301 ATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILM 360 Query: 2307 QNLRFPDNPVVSSNAKDLIRGLLVKEPENRL-GTLRGAAEIKQHPFFEGLNWALI--RSV 2477 ++++FP +SS+AK L+ GLL+K+P RL G A EI +H FF G+NW + + + Sbjct: 361 EDIKFP--RTLSSDAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFSGVNWQDVYDKKL 418 Query: 2478 APP 2486 PP Sbjct: 419 VPP 421
>Q2LZZ7:ST38L_DROPS Serine/threonine-protein kinase 38-like - Drosophila pseudoobscura| (Fruit fly) Length = 458 Score = 106 bits (264), Expect = 6e-22 Identities = 54/157 (34%), Positives = 96/157 (61%) Frame = +3 Query: 1416 LALQQGPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQA 1595 L L++ LG+++F LK +G G G V L + D+ ++A+KV+ ++ ++++ +A Sbjct: 80 LRLKRLRLGVEDFEALKVIGRGAFGEVRLVQKKDTGHVYAMKVLRKADMLEKEQVAHVRA 139 Query: 1596 EREILEMLDHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVA 1775 ER++L DH ++ +Y F L+ME+ PGGD+ L ++ + E +FY++ Sbjct: 140 ERDVLVEADHQWVVKMYYSFQDQVNLYLIMEFLPGGDMMTLLMKKD--TLSEEGTQFYIS 197 Query: 1776 EVLLALEYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 E LA++ +H LG I+RD+KP+N+L+ GH+ LSDF Sbjct: 198 ETALAIDSIHKLGFIHRDIKPDNLLLDARGHLKLSDF 234 Score = 88.6 bits (218), Expect = 1e-16 Identities = 50/131 (38%), Positives = 71/131 (54%), Gaps = 5/131 (3%) Frame = +3 Query: 2127 ARSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVS 2306 A + S VGT +Y+APE+ G+G A DWW+ GV +YE+L G PF +T V++ Sbjct: 283 ALAYSTVGTPDYIAPEVFLQTGYGPACDWWSLGVIMYEMLMGYPPFCSDNPQDTYRKVMN 342 Query: 2307 --QNLRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPFFEGLNWALIR--- 2471 + L FP +S AK+ I E + RLG+ RG ++K PFF G++W IR Sbjct: 343 WRETLIFPPEIPISEEAKETIIKFCC-EADRRLGSQRGLEDLKSVPFFRGVDWEHIRERP 401 Query: 2472 SVAPPETRPCD 2504 + P E R D Sbjct: 402 AAIPVEVRSID 412
>P49673:KAPC_ASCSU cAMP-dependent protein kinase catalytic subunit - Ascaris suum (Pig| roundworm) (Ascaris lumbricoides) Length = 337 Score = 106 bits (264), Expect = 6e-22 Identities = 54/150 (36%), Positives = 85/150 (56%) Frame = +3 Query: 1437 LGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEM 1616 L +D+F + +G G G VYL + S+ FALK M I ++S ++ +E+ +L Sbjct: 24 LNVDDFDRICTIGTGSFGRVYLVQHRASEQYFALKKMAIREVVSMRQTEHVHSEKRLLSR 83 Query: 1617 LDHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALE 1796 L HPF+ +Y ++ EY GG+L + R+F ARFY AE++ AL+ Sbjct: 84 LSHPFIVKMYCASWDKYNLYMLFEYLAGGEL--FSYLRASRTFSNSMARFYAAEIVCALQ 141 Query: 1797 YLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 YLH + YRDLKPEN+++ +GH+ ++DF Sbjct: 142 YLHSKNIAYRDLKPENLMLNKEGHLKMTDF 171 Score = 90.1 bits (222), Expect = 4e-17 Identities = 48/122 (39%), Positives = 72/122 (59%), Gaps = 3/122 (2%) Frame = +3 Query: 2130 RSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQ 2309 R+ + GT EYLAPE+I GH +AVDWW+ GV +YE++ G PFRG DE ++ Sbjct: 180 RTWTMCGTPEYLAPEVIGNKGHDTAVDWWSLGVLIYEMMIGIPPFRGKTLDEIYEKIILG 239 Query: 2310 NLRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLR-GAAEIKQHPFFEGLNWALIRS--VA 2480 LRF + AKDL++ LL + RLG + GAA++ H +F ++W +++ + Sbjct: 240 KLRFTRS--FDLFAKDLVKKLLQVDRTQRLGNQKDGAADVMNHKWFTDIDWDDVQNMKLT 297 Query: 2481 PP 2486 PP Sbjct: 298 PP 299
>Q7TPS0:KS6A6_MOUSE Ribosomal protein S6 kinase alpha-6 - Mus musculus (Mouse)| Length = 764 Score = 105 bits (263), Expect = 8e-22 Identities = 61/148 (41%), Positives = 92/148 (62%), Gaps = 3/148 (2%) Frame = +3 Query: 1452 FRLLKRLGCGDIGTVYLAELV---DSDCLFALKVMDIEYLISRKKMLRAQAEREILEMLD 1622 F LLK LG G G V+L D+ L+A+KV+ L R ++ R + ER+IL ++ Sbjct: 93 FDLLKVLGQGSFGKVFLVRKKTGPDAGQLYAMKVLRKASLKVRDRV-RTKMERDILVEVN 151 Query: 1623 HPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALEYL 1802 HPF+ L+ F T+ L++++ GGD+ ++ F E +FY+AE+ LAL++L Sbjct: 152 HPFIVKLHYAFQTEGKLYLILDFLRGGDVFTRLSKEV--LFTEEDVKFYLAELALALDHL 209 Query: 1803 HMLGVIYRDLKPENILVRDDGHIMLSDF 1886 H LG++YRDLKPENIL+ + GHI L+DF Sbjct: 210 HRLGIVYRDLKPENILLDEIGHIKLTDF 237 Score = 99.0 bits (245), Expect = 1e-19 Identities = 47/123 (38%), Positives = 74/123 (60%), Gaps = 2/123 (1%) Frame = +3 Query: 2124 EARSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVV 2303 E ++ SF GT EY+APE++ H + DWW++GV ++E+L G PF+G +ET+ ++ Sbjct: 247 EKKAYSFCGTVEYMAPEVVNRRAHSQSADWWSYGVLMFEMLTGTLPFQGKDRNETMNMIL 306 Query: 2304 SQNLRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPFFEGLNWALI--RSV 2477 L P +S+ A+ L+R L + P NRLG+ G E+K+H FF ++W + R V Sbjct: 307 KAKLGMPQ--FLSAEAQSLLRMLFKRNPANRLGS-EGVEEVKRHAFFASIDWNKLYKREV 363 Query: 2478 APP 2486 PP Sbjct: 364 QPP 366 Score = 52.4 bits (124), Expect = 1e-05 Identities = 37/106 (34%), Positives = 54/106 (50%), Gaps = 9/106 (8%) Frame = +3 Query: 2151 THEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGND---ETLANVVSQNLRF 2321 T ++APE++ G+ +A D W+ GV LY +L G TPF ND E L + N RF Sbjct: 605 TANFVAPEVLTQQGYDAACDIWSLGVLLYTMLAGYTPFSNGPNDTPEEILLRI--GNGRF 662 Query: 2322 P------DNPVVSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPF 2441 DN +S AKDL+ +L +P R A ++ +HP+ Sbjct: 663 SLSGGIWDN--ISRGAKDLLSHMLHMDPHQRY----TAEQVLKHPW 702 Score = 43.9 bits (102), Expect = 0.004 Identities = 40/138 (28%), Positives = 59/138 (42%), Gaps = 1/138 (0%) Frame = +3 Query: 1452 FRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEML-DHP 1628 + L + +G G S+ FA+K++D K E EIL HP Sbjct: 446 YELKEDIGIGSYSVCKRCIHSASNVEFAVKIID-------KNKRDPSEEIEILMRYGQHP 498 Query: 1629 FLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALEYLHM 1808 + +L F LV + GG+L L + + F E A + + +E LH Sbjct: 499 NIISLKEVFDDGKYVYLVTDLMKGGEL--LDRILKKKCFSEQEASNVLYVITKTVECLHS 556 Query: 1809 LGVIYRDLKPENILVRDD 1862 GV++RDLKP NIL D+ Sbjct: 557 QGVVHRDLKPSNILYMDE 574
>Q02111:KPCT_MOUSE Protein kinase C theta type - Mus musculus (Mouse)| Length = 707 Score = 105 bits (263), Expect = 8e-22 Identities = 62/163 (38%), Positives = 94/163 (57%), Gaps = 1/163 (0%) Frame = +3 Query: 1401 ITIRQLALQQGPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKM 1580 +++R+ +LQ L +D+F L K LG G G V+LAE ++ FA+K + + ++ + Sbjct: 364 VSMRRTSLQL-KLKIDDFILHKMLGKGSFGKVFLAEFKRTNQFFAIKALKKDVVLMDDDV 422 Query: 1581 LRAQAEREILEML-DHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPS 1757 E+ +L + +HPFL ++ F T VMEY GGDL + Q F Sbjct: 423 ECTMVEKRVLSLAWEHPFLTHMFCTFQTKENLFFVMEYLNGGDL--MYHIQSCHKFDLSR 480 Query: 1758 ARFYVAEVLLALEYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 A FY AEV+L L++LH G++YRDLK +NIL+ DGHI ++DF Sbjct: 481 ATFYAAEVILGLQFLHSKGIVYRDLKLDNILLDRDGHIKIADF 523 Score = 103 bits (256), Expect = 5e-21 Identities = 54/126 (42%), Positives = 79/126 (62%), Gaps = 1/126 (0%) Frame = +3 Query: 2124 EARSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVV 2303 +A++N+F GT +Y+APEI+ G + +VDWW+FGV +YE+L G++PF G +E ++ Sbjct: 533 DAKTNTFCGTPDYIAPEILLGQKYNHSVDWWSFGVLVYEMLIGQSPFHGQDEEELFHSIR 592 Query: 2304 SQNLRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPFFEGLNW-ALIRSVA 2480 N +P + AKDL+ L V+EPE RLG +RG +I+QHP F +NW L R Sbjct: 593 MDNPFYP--RWLEREAKDLLVKLFVREPEKRLG-VRG--DIRQHPLFREINWEELERKEI 647 Query: 2481 PPETRP 2498 P RP Sbjct: 648 DPPFRP 653
>Q64595:KGP2_RAT cGMP-dependent protein kinase 2 - Rattus norvegicus (Rat)| Length = 762 Score = 105 bits (262), Expect = 1e-21 Identities = 57/147 (38%), Positives = 89/147 (60%), Gaps = 1/147 (0%) Frame = +3 Query: 1449 NFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEMLDHP 1628 N ++ LG G G V L ++ + + FA+K + ++++ K+ +E+ ILE L P Sbjct: 452 NLEIIATLGVGGFGRVELVKVKNENIAFAMKCIRKKHIVDTKQQEHVYSEKRILEELCSP 511 Query: 1629 FLPTLYAHFTTDNLSCLVMEYCPGGDL-HVLRQRQPGRSFPEPSARFYVAEVLLALEYLH 1805 F+ LY F + +++E C GG+L +LR R SF EP+++F VA V A +YLH Sbjct: 512 FIVKLYRTFKDNKYVYMLLEACLGGELWSILRDRG---SFDEPTSKFCVACVTEAFDYLH 568 Query: 1806 MLGVIYRDLKPENILVRDDGHIMLSDF 1886 LG+IYRDLKPEN+++ DG++ L DF Sbjct: 569 RLGIIYRDLKPENLILDADGYLKLVDF 595 Score = 82.4 bits (202), Expect = 9e-15 Identities = 45/118 (38%), Positives = 69/118 (58%), Gaps = 2/118 (1%) Frame = +3 Query: 2139 SFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQNLR 2318 +F GT EY+APE+I GH +VD+W+ G+ +YELL G PF G T N++ + + Sbjct: 609 TFCGTPEYVAPEVILNKGHDFSVDFWSLGILVYELLTGNPPFSGIDQMMTY-NLILKGIE 667 Query: 2319 FPDNP-VVSSNAKDLIRGLLVKEPENRLGTLR-GAAEIKQHPFFEGLNWALIRSVAPP 2486 D P ++ +DLIR L + P RLG L+ G +IK+H + G NW +++ + P Sbjct: 668 KMDFPRKITRRPEDLIRRLCRQNPTERLGNLKNGINDIKKHRWLNGFNWEGLKARSLP 725
>P31748:AKT_MLVAT AKT kinase-transforming protein - AKT8 murine leukemia virus| Length = 501 Score = 105 bits (262), Expect = 1e-21 Identities = 60/158 (37%), Positives = 90/158 (56%), Gaps = 1/158 (0%) Frame = +3 Query: 1416 LALQQGPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQA 1595 LA + + ++ F LK LG G G V L + + +A+K++ E ++++ ++ Sbjct: 159 LAKPKHRVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLT 218 Query: 1596 EREILEMLDHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVA 1775 E +L+ HPFL L F T + C VMEY GG+L R+ R F E ARFY A Sbjct: 219 ENRVLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRE--RVFSEDRARFYGA 276 Query: 1776 EVLLALEYLHM-LGVIYRDLKPENILVRDDGHIMLSDF 1886 E++ AL+YLH V+YRDLK EN+++ DGHI ++DF Sbjct: 277 EIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDF 314 Score = 93.6 bits (231), Expect = 4e-18 Identities = 48/123 (39%), Positives = 72/123 (58%), Gaps = 3/123 (2%) Frame = +3 Query: 2127 ARSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVS 2306 A +F GT EYLAPE+++ + +G AVDWW GV +YE++ GR PF +++ ++ Sbjct: 325 ATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILM 384 Query: 2307 QNLRFPDNPVVSSNAKDLIRGLLVKEPENRL-GTLRGAAEIKQHPFFEGLNWALI--RSV 2477 + +RFP + AK L+ GLL K+P RL G A EI QH FF + W + + + Sbjct: 385 EEIRFP--RTLGPEAKSLLSGLLKKDPTQRLGGGSEDAKEIMQHRFFANIVWQDVYEKKL 442 Query: 2478 APP 2486 +PP Sbjct: 443 SPP 445
>P47196:AKT1_RAT RAC-alpha serine/threonine-protein kinase - Rattus norvegicus (Rat)| Length = 480 Score = 105 bits (262), Expect = 1e-21 Identities = 60/158 (37%), Positives = 90/158 (56%), Gaps = 1/158 (0%) Frame = +3 Query: 1416 LALQQGPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQA 1595 LA + + ++ F LK LG G G V L + + +A+K++ E ++++ ++ Sbjct: 138 LAKPKHRVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLT 197 Query: 1596 EREILEMLDHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVA 1775 E +L+ HPFL L F T + C VMEY GG+L R+ R F E ARFY A Sbjct: 198 ENRVLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRE--RVFSEDRARFYGA 255 Query: 1776 EVLLALEYLHM-LGVIYRDLKPENILVRDDGHIMLSDF 1886 E++ AL+YLH V+YRDLK EN+++ DGHI ++DF Sbjct: 256 EIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDF 293 Score = 93.6 bits (231), Expect = 4e-18 Identities = 48/123 (39%), Positives = 72/123 (58%), Gaps = 3/123 (2%) Frame = +3 Query: 2127 ARSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVS 2306 A +F GT EYLAPE+++ + +G AVDWW GV +YE++ GR PF +++ ++ Sbjct: 304 ATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILM 363 Query: 2307 QNLRFPDNPVVSSNAKDLIRGLLVKEPENRL-GTLRGAAEIKQHPFFEGLNWALI--RSV 2477 + +RFP + AK L+ GLL K+P RL G A EI QH FF + W + + + Sbjct: 364 EEIRFP--RTLGPEAKSLLSGLLKKDPTQRLGGGSEDAKEIMQHRFFANIVWQDVYEKKL 421 Query: 2478 APP 2486 +PP Sbjct: 422 SPP 424
>P31750:AKT1_MOUSE RAC-alpha serine/threonine-protein kinase - Mus musculus (Mouse)| Length = 480 Score = 105 bits (262), Expect = 1e-21 Identities = 60/158 (37%), Positives = 90/158 (56%), Gaps = 1/158 (0%) Frame = +3 Query: 1416 LALQQGPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQA 1595 LA + + ++ F LK LG G G V L + + +A+K++ E ++++ ++ Sbjct: 138 LAKPKHRVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLT 197 Query: 1596 EREILEMLDHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVA 1775 E +L+ HPFL L F T + C VMEY GG+L R+ R F E ARFY A Sbjct: 198 ENRVLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRE--RVFSEDRARFYGA 255 Query: 1776 EVLLALEYLHM-LGVIYRDLKPENILVRDDGHIMLSDF 1886 E++ AL+YLH V+YRDLK EN+++ DGHI ++DF Sbjct: 256 EIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDF 293 Score = 91.3 bits (225), Expect = 2e-17 Identities = 47/123 (38%), Positives = 71/123 (57%), Gaps = 3/123 (2%) Frame = +3 Query: 2127 ARSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVS 2306 A +F GT EYLAPE+++ + +G AVDWW GV +YE++ GR PF +++ ++ Sbjct: 304 ATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILM 363 Query: 2307 QNLRFPDNPVVSSNAKDLIRGLLVKEPENRL-GTLRGAAEIKQHPFFEGLNWALI--RSV 2477 + + FP + AK L+ GLL K+P RL G A EI QH FF + W + + + Sbjct: 364 EEIAFP--RTLGPEAKSLLSGLLKKDPTQRLGGGSEDAKEIMQHRFFANIVWQDVYEKKL 421 Query: 2478 APP 2486 +PP Sbjct: 422 SPP 424
>P31749:AKT1_HUMAN RAC-alpha serine/threonine-protein kinase - Homo sapiens (Human)| Length = 480 Score = 105 bits (262), Expect = 1e-21 Identities = 60/158 (37%), Positives = 90/158 (56%), Gaps = 1/158 (0%) Frame = +3 Query: 1416 LALQQGPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQA 1595 LA + + ++ F LK LG G G V L + + +A+K++ E ++++ ++ Sbjct: 138 LAKPKHRVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLT 197 Query: 1596 EREILEMLDHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVA 1775 E +L+ HPFL L F T + C VMEY GG+L R+ R F E ARFY A Sbjct: 198 ENRVLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRE--RVFSEDRARFYGA 255 Query: 1776 EVLLALEYLHM-LGVIYRDLKPENILVRDDGHIMLSDF 1886 E++ AL+YLH V+YRDLK EN+++ DGHI ++DF Sbjct: 256 EIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDF 293 Score = 97.1 bits (240), Expect = 4e-19 Identities = 49/123 (39%), Positives = 74/123 (60%), Gaps = 3/123 (2%) Frame = +3 Query: 2127 ARSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVS 2306 A +F GT EYLAPE+++ + +G AVDWW GV +YE++ GR PF +++ ++ Sbjct: 304 ATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILM 363 Query: 2307 QNLRFPDNPVVSSNAKDLIRGLLVKEPENRL-GTLRGAAEIKQHPFFEGLNWALI--RSV 2477 + +RFP + AK L+ GLL K+P+ RL G A EI QH FF G+ W + + + Sbjct: 364 EEIRFP--RTLGPEAKSLLSGLLKKDPKQRLGGGSEDAKEIMQHRFFAGIVWQHVYEKKL 421 Query: 2478 APP 2486 +PP Sbjct: 422 SPP 424
>P67999:KS6B1_RAT Ribosomal protein S6 kinase beta-1 - Rattus norvegicus (Rat)| Length = 525 Score = 105 bits (261), Expect = 1e-21 Identities = 63/166 (37%), Positives = 98/166 (59%), Gaps = 6/166 (3%) Frame = +3 Query: 1407 IRQLALQQGPLGL--DNFRLLKRLGCGDIGTVYLAELV---DSDCLFALKVMDIEYLI-S 1568 I + ++ +GP + + F LL+ LG G G V+ V ++ +FA+KV+ ++ + Sbjct: 74 ISETSVNRGPEKIRPECFELLRVLGKGGYGKVFQVRKVTGANTGKIFAMKVLKKAMIVRN 133 Query: 1569 RKKMLRAQAEREILEMLDHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFP 1748 K +AER ILE + HPF+ L F T L++EY GG+L + +R+ F Sbjct: 134 AKDTAHTKAERNILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLEREG--IFM 191 Query: 1749 EPSARFYVAEVLLALEYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 E +A FY+AE+ +AL +LH G+IYRDLKPENI++ GH+ L+DF Sbjct: 192 EDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDF 237 Score = 100 bits (248), Expect = 4e-20 Identities = 49/121 (40%), Positives = 72/121 (59%), Gaps = 3/121 (2%) Frame = +3 Query: 2133 SNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQN 2312 +++F GT EY+APEI+ GH AVDWW+ G +Y++L G PF G +T+ ++ Sbjct: 250 THTFCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCK 309 Query: 2313 LRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLRG-AAEIKQHPFFEGLNW--ALIRSVAP 2483 L P P ++ A+DL++ LL + +RLG G A E++ HPFF +NW L R V P Sbjct: 310 LNLP--PYLTQEARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFFRHINWEELLARKVEP 367 Query: 2484 P 2486 P Sbjct: 368 P 368
>P67998:KS6B1_RABIT Ribosomal protein S6 kinase beta-1 - Oryctolagus cuniculus (Rabbit)| Length = 525 Score = 105 bits (261), Expect = 1e-21 Identities = 63/166 (37%), Positives = 98/166 (59%), Gaps = 6/166 (3%) Frame = +3 Query: 1407 IRQLALQQGPLGL--DNFRLLKRLGCGDIGTVYLAELV---DSDCLFALKVMDIEYLI-S 1568 I + ++ +GP + + F LL+ LG G G V+ V ++ +FA+KV+ ++ + Sbjct: 74 ISETSVNRGPEKIRPECFELLRVLGKGGYGKVFQVRKVTGANTGKIFAMKVLKKAMIVRN 133 Query: 1569 RKKMLRAQAEREILEMLDHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFP 1748 K +AER ILE + HPF+ L F T L++EY GG+L + +R+ F Sbjct: 134 AKDTAHTKAERNILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLEREG--IFM 191 Query: 1749 EPSARFYVAEVLLALEYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 E +A FY+AE+ +AL +LH G+IYRDLKPENI++ GH+ L+DF Sbjct: 192 EDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDF 237 Score = 100 bits (248), Expect = 4e-20 Identities = 49/121 (40%), Positives = 72/121 (59%), Gaps = 3/121 (2%) Frame = +3 Query: 2133 SNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQN 2312 +++F GT EY+APEI+ GH AVDWW+ G +Y++L G PF G +T+ ++ Sbjct: 250 THTFCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCK 309 Query: 2313 LRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLRG-AAEIKQHPFFEGLNW--ALIRSVAP 2483 L P P ++ A+DL++ LL + +RLG G A E++ HPFF +NW L R V P Sbjct: 310 LNLP--PYLTQEARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFFRHINWEELLARKVEP 367 Query: 2484 P 2486 P Sbjct: 368 P 368
>Q8BSK8:KS6B1_MOUSE Ribosomal protein S6 kinase beta-1 - Mus musculus (Mouse)| Length = 525 Score = 105 bits (261), Expect = 1e-21 Identities = 63/166 (37%), Positives = 98/166 (59%), Gaps = 6/166 (3%) Frame = +3 Query: 1407 IRQLALQQGPLGL--DNFRLLKRLGCGDIGTVYLAELV---DSDCLFALKVMDIEYLI-S 1568 I + ++ +GP + + F LL+ LG G G V+ V ++ +FA+KV+ ++ + Sbjct: 74 ISETSVNRGPEKIRPECFELLRVLGKGGYGKVFQVRKVTGANTGKIFAMKVLKKAMIVRN 133 Query: 1569 RKKMLRAQAEREILEMLDHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFP 1748 K +AER ILE + HPF+ L F T L++EY GG+L + +R+ F Sbjct: 134 AKDTAHTKAERNILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLEREG--IFM 191 Query: 1749 EPSARFYVAEVLLALEYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 E +A FY+AE+ +AL +LH G+IYRDLKPENI++ GH+ L+DF Sbjct: 192 EDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDF 237 Score = 100 bits (248), Expect = 4e-20 Identities = 49/121 (40%), Positives = 72/121 (59%), Gaps = 3/121 (2%) Frame = +3 Query: 2133 SNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQN 2312 +++F GT EY+APEI+ GH AVDWW+ G +Y++L G PF G +T+ ++ Sbjct: 250 THTFCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCK 309 Query: 2313 LRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLRG-AAEIKQHPFFEGLNW--ALIRSVAP 2483 L P P ++ A+DL++ LL + +RLG G A E++ HPFF +NW L R V P Sbjct: 310 LNLP--PYLTQEARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFFRHINWEELLARKVEP 367 Query: 2484 P 2486 P Sbjct: 368 P 368
>P23443:KS6B1_HUMAN Ribosomal protein S6 kinase beta-1 - Homo sapiens (Human)| Length = 525 Score = 105 bits (261), Expect = 1e-21 Identities = 63/166 (37%), Positives = 98/166 (59%), Gaps = 6/166 (3%) Frame = +3 Query: 1407 IRQLALQQGPLGL--DNFRLLKRLGCGDIGTVYLAELV---DSDCLFALKVMDIEYLI-S 1568 I + ++ +GP + + F LL+ LG G G V+ V ++ +FA+KV+ ++ + Sbjct: 74 ISETSVNRGPEKIRPECFELLRVLGKGGYGKVFQVRKVTGANTGKIFAMKVLKKAMIVRN 133 Query: 1569 RKKMLRAQAEREILEMLDHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFP 1748 K +AER ILE + HPF+ L F T L++EY GG+L + +R+ F Sbjct: 134 AKDTAHTKAERNILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLEREG--IFM 191 Query: 1749 EPSARFYVAEVLLALEYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 E +A FY+AE+ +AL +LH G+IYRDLKPENI++ GH+ L+DF Sbjct: 192 EDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDF 237 Score = 100 bits (248), Expect = 4e-20 Identities = 49/121 (40%), Positives = 72/121 (59%), Gaps = 3/121 (2%) Frame = +3 Query: 2133 SNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQN 2312 +++F GT EY+APEI+ GH AVDWW+ G +Y++L G PF G +T+ ++ Sbjct: 250 THTFCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCK 309 Query: 2313 LRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLRG-AAEIKQHPFFEGLNW--ALIRSVAP 2483 L P P ++ A+DL++ LL + +RLG G A E++ HPFF +NW L R V P Sbjct: 310 LNLP--PYLTQEARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFFRHINWEELLARKVEP 367 Query: 2484 P 2486 P Sbjct: 368 P 368
>Q6TJY3:KS6B1_BOVIN Ribosomal protein S6 kinase beta-1 - Bos taurus (Bovine)| Length = 527 Score = 105 bits (261), Expect = 1e-21 Identities = 63/166 (37%), Positives = 98/166 (59%), Gaps = 6/166 (3%) Frame = +3 Query: 1407 IRQLALQQGPLGL--DNFRLLKRLGCGDIGTVYLAELV---DSDCLFALKVMDIEYLI-S 1568 I + ++ +GP + + F LL+ LG G G V+ V ++ +FA+KV+ ++ + Sbjct: 74 ISETSVNRGPEKIRPECFELLRVLGKGGYGKVFQVRKVTGANTGKIFAMKVLKKAMIVRN 133 Query: 1569 RKKMLRAQAEREILEMLDHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFP 1748 K +AER ILE + HPF+ L F T L++EY GG+L + +R+ F Sbjct: 134 AKDTAHTKAERNILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLEREG--IFM 191 Query: 1749 EPSARFYVAEVLLALEYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 E +A FY+AE+ +AL +LH G+IYRDLKPENI++ GH+ L+DF Sbjct: 192 EDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDF 237 Score = 100 bits (248), Expect = 4e-20 Identities = 49/121 (40%), Positives = 72/121 (59%), Gaps = 3/121 (2%) Frame = +3 Query: 2133 SNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQN 2312 +++F GT EY+APEI+ GH AVDWW+ G +Y++L G PF G +T+ ++ Sbjct: 250 THTFCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCK 309 Query: 2313 LRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLRG-AAEIKQHPFFEGLNW--ALIRSVAP 2483 L P P ++ A+DL++ LL + +RLG G A E++ HPFF +NW L R V P Sbjct: 310 LNLP--PYLTQEARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFFRHINWEELLARKVEP 367 Query: 2484 P 2486 P Sbjct: 368 P 368
>P43057:KPC1_CANAL Protein kinase C-like 1 - Candida albicans (Yeast)| Length = 1097 Score = 105 bits (261), Expect = 1e-21 Identities = 60/155 (38%), Positives = 89/155 (57%), Gaps = 5/155 (3%) Frame = +3 Query: 1437 LGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEM 1616 +GLD+F+ L LG G+ G V LAE + L A+KV+ ++++ + ++E+ + Sbjct: 765 VGLDDFQFLAVLGKGNFGKVMLAESRHTSKLCAIKVLKKDFIVENDEAESVKSEKRVFLT 824 Query: 1617 LD---HPFLPTLYAHFTTDNLSCLVMEYCPGGDL--HVLRQRQPGRSFPEPSARFYVAEV 1781 + HPFL L+ F T+N VMEY GGDL H+ + R F A+FY EV Sbjct: 825 ANKEMHPFLLNLHCCFQTENRIYFVMEYISGGDLMWHIQKNR-----FTAKRAKFYACEV 879 Query: 1782 LLALEYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 LL L+Y H G++YRDLK +NIL+ GHI + D+ Sbjct: 880 LLGLKYFHDNGIVYRDLKLDNILLTTKGHIKIGDY 914 Score = 87.0 bits (214), Expect = 4e-16 Identities = 39/113 (34%), Positives = 72/113 (63%), Gaps = 1/113 (0%) Frame = +3 Query: 2124 EARSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVV 2303 ++ +++F GT E++APEI+ G + +VDWW FGV L+++L ++PF+G D+ + Sbjct: 924 KSTTSTFCGTPEFMAPEIVAGKAYDRSVDWWAFGVLLFQMLLCQSPFKGDDEDDIFNAIE 983 Query: 2304 SQNLRFPDNPVVSSNAKDLIRGLLVKEPENRLGT-LRGAAEIKQHPFFEGLNW 2459 + +++P N +S +++ LL K+P RLG+ + A EI +HP+F +N+ Sbjct: 984 NDEVKYPIN--LSRQTVLVLQALLTKDPSQRLGSGPKDAEEIMEHPYFHDVNF 1034
>Q98TY9:AKT1_XENLA RAC-alpha serine/threonine-protein kinase - Xenopus laevis (African| clawed frog) Length = 481 Score = 105 bits (261), Expect = 1e-21 Identities = 58/149 (38%), Positives = 86/149 (57%), Gaps = 1/149 (0%) Frame = +3 Query: 1443 LDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEMLD 1622 ++ F LK LG G G V L + + +A+K++ E ++++ ++ E +L+ Sbjct: 148 MNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRVLQNSR 207 Query: 1623 HPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALEYL 1802 HPFL L F T + C VMEY GG+L R+ R F E ARFY AE++ AL+YL Sbjct: 208 HPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRE--RIFSEDRARFYGAEIVSALDYL 265 Query: 1803 HM-LGVIYRDLKPENILVRDDGHIMLSDF 1886 H V+YRDLK EN+++ DGHI ++DF Sbjct: 266 HSEKNVVYRDLKLENLMLDKDGHIKITDF 294 Score = 94.7 bits (234), Expect = 2e-18 Identities = 49/123 (39%), Positives = 73/123 (59%), Gaps = 3/123 (2%) Frame = +3 Query: 2127 ARSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVS 2306 A +F GT EYLAPE+++ + +G AVDWW GV +YE++ GR PF +++ ++ Sbjct: 305 ATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILM 364 Query: 2307 QNLRFPDNPVVSSNAKDLIRGLLVKEPENRL-GTLRGAAEIKQHPFFEGLNWALI--RSV 2477 + +RFP + AK L+ GLL K+P+ RL G A EI QH FF G+ W + + + Sbjct: 365 EEIRFP--RTLLPEAKSLLSGLLKKDPKQRLGGGPDDAKEIMQHKFFAGIVWQDVYEKKL 422 Query: 2478 APP 2486 PP Sbjct: 423 VPP 425
>Q01314:AKT1_BOVIN RAC-alpha serine/threonine-protein kinase - Bos taurus (Bovine)| Length = 480 Score = 105 bits (261), Expect = 1e-21 Identities = 60/158 (37%), Positives = 91/158 (57%), Gaps = 1/158 (0%) Frame = +3 Query: 1416 LALQQGPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQA 1595 LA + + +++F LK LG G G V L + + +A+K++ E ++++ ++ Sbjct: 138 LAKPKHRVTMNDFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLT 197 Query: 1596 EREILEMLDHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVA 1775 E +L+ HPFL L F T + C VMEY GG+L R+ R F E ARFY A Sbjct: 198 ENRVLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRE--RVFSEDRARFYGA 255 Query: 1776 EVLLALEYLHM-LGVIYRDLKPENILVRDDGHIMLSDF 1886 E++ AL+YLH V+YRDLK EN+++ DGHI ++DF Sbjct: 256 EIVSALDYLHSEKEVVYRDLKLENLMLDKDGHIKITDF 293 Score = 95.9 bits (237), Expect = 8e-19 Identities = 49/123 (39%), Positives = 74/123 (60%), Gaps = 3/123 (2%) Frame = +3 Query: 2127 ARSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVS 2306 A +F GT EYLAPE+++ + +G AVDWW GV +YE++ GR PF +++ ++ Sbjct: 304 ATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILM 363 Query: 2307 QNLRFPDNPVVSSNAKDLIRGLLVKEPENRL-GTLRGAAEIKQHPFFEGLNWALI--RSV 2477 + +RFP +S AK L+ GLL K+P+ RL G A EI QH FF + W + + + Sbjct: 364 EEIRFP--RTLSPEAKSLLSGLLKKDPKQRLGGGSEDAKEIMQHRFFASIVWQDVYEKKL 421 Query: 2478 APP 2486 +PP Sbjct: 422 SPP 424
>Q6P5Z2:PKN3_HUMAN Serine/threonine-protein kinase N3 - Homo sapiens (Human)| Length = 889 Score = 104 bits (260), Expect = 2e-21 Identities = 61/154 (39%), Positives = 89/154 (57%), Gaps = 3/154 (1%) Frame = +3 Query: 1434 PLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILE 1613 P L +FR L LG G G V L + + +A+K + + ++SR ++ E+ ILE Sbjct: 553 PPRLQDFRCLAVLGRGHFGKVLLVQFKGTGKYYAIKALKKQEVLSRDEIESLYCEKRILE 612 Query: 1614 MLD---HPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVL 1784 + HPFL +L A F T + +C V E+ PGGDL + FPEP ARFYVA V+ Sbjct: 613 AVGCTGHPFLLSLLACFQTSSHACFVTEFVPGGDLMMQIHEDV---FPEPQARFYVACVV 669 Query: 1785 LALEYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 L L++LH +IYRDLK +N+L+ G + ++DF Sbjct: 670 LGLQFLHEKKIIYRDLKLDNLLLDAQGFLKIADF 703 Score = 90.9 bits (224), Expect = 3e-17 Identities = 50/122 (40%), Positives = 70/122 (57%), Gaps = 3/122 (2%) Frame = +3 Query: 2130 RSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQ 2309 R+++F GT E+LAPE++ + + AVDWW GV LYE+L G PF G +E +V+ Sbjct: 715 RTSTFCGTPEFLAPEVLTQEAYTRAVDWWGLGVLLYEMLVGECPFPGDTEEEVFDCIVNM 774 Query: 2310 NLRFPDNPVVSSNAKDLIRGLLVKEPENRLGT-LRGAAEIKQHPFFEGLNW--ALIRSVA 2480 + +P +S + I+ LL K PE RLG + A EIK PFF NW L R++ Sbjct: 775 DAPYPG--FLSVQGLEFIQKLLQKCPEKRLGAGEQDAEEIKVQPFFRTTNWQALLARTIQ 832 Query: 2481 PP 2486 PP Sbjct: 833 PP 834
>Q04759:KPCT_HUMAN Protein kinase C theta type - Homo sapiens (Human)| Length = 706 Score = 104 bits (260), Expect = 2e-21 Identities = 55/126 (43%), Positives = 79/126 (62%), Gaps = 1/126 (0%) Frame = +3 Query: 2124 EARSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVV 2303 +A++N+F GT +Y+APEI+ G + +VDWW+FGV LYE+L G++PF G +E ++ Sbjct: 533 DAKTNTFCGTPDYIAPEILLGQKYNHSVDWWSFGVLLYEMLIGQSPFHGQDEEELFHSIR 592 Query: 2304 SQNLRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPFFEGLNW-ALIRSVA 2480 N +P + AKDL+ L V+EPE RLG +RG +I+QHP F +NW L R Sbjct: 593 MDNPFYP--RWLEKEAKDLLVKLFVREPEKRLG-VRG--DIRQHPLFREINWEELERKEI 647 Query: 2481 PPETRP 2498 P RP Sbjct: 648 DPPFRP 653 Score = 102 bits (255), Expect = 7e-21 Identities = 57/151 (37%), Positives = 86/151 (56%), Gaps = 1/151 (0%) Frame = +3 Query: 1437 LGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEM 1616 L +++F L K LG G G V+LAE ++ FA+K + + ++ + E+ +L + Sbjct: 375 LKIEDFILHKMLGKGSFGKVFLAEFKKTNQFFAIKALKKDVVLMDDDVECTMVEKRVLSL 434 Query: 1617 L-DHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLAL 1793 +HPFL ++ F T VMEY GGDL + Q F A FY AE++L L Sbjct: 435 AWEHPFLTHMFCTFQTKENLFFVMEYLNGGDL--MYHIQSCHKFDLSRATFYAAEIILGL 492 Query: 1794 EYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 ++LH G++YRDLK +NIL+ DGHI ++DF Sbjct: 493 QFLHSKGIVYRDLKLDNILLDKDGHIKIADF 523
>Q9WTQ0:KPCT_RAT Protein kinase C theta type - Rattus norvegicus (Rat)| Length = 707 Score = 104 bits (259), Expect = 2e-21 Identities = 62/159 (38%), Positives = 88/159 (55%), Gaps = 1/159 (0%) Frame = +3 Query: 1413 QLALQQGPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQ 1592 Q A Q L +D+F L K LG G G V+LAE + FA+K + + ++ + Sbjct: 367 QRASLQLKLKIDDFILHKMLGKGSFGKVFLAEFKRTKQFFAIKALKKDVVLMDDDVECTM 426 Query: 1593 AEREILEML-DHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFY 1769 E+ +L + +HPFL ++ F T VMEY GGDL + Q F A FY Sbjct: 427 VEKRVLSLAWEHPFLTHMFCTFQTKENLFFVMEYLNGGDL--MYHIQSCHKFDLSRATFY 484 Query: 1770 VAEVLLALEYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 AEV+L L++LH G++YRDLK +NIL+ DGHI ++DF Sbjct: 485 AAEVILGLQFLHSKGIVYRDLKLDNILLDRDGHIKIADF 523 Score = 104 bits (259), Expect = 2e-21 Identities = 55/126 (43%), Positives = 79/126 (62%), Gaps = 1/126 (0%) Frame = +3 Query: 2124 EARSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVV 2303 +A++N+F GT +Y+APEI+ G + +VDWW+FGV LYE+L G++PF G +E ++ Sbjct: 533 DAKTNTFCGTPDYIAPEILLGQKYNHSVDWWSFGVLLYEMLIGQSPFHGQDEEELFHSIR 592 Query: 2304 SQNLRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPFFEGLNW-ALIRSVA 2480 N +P + AKDL+ L V+EPE RLG +RG +I+QHP F +NW L R Sbjct: 593 MDNPFYP--RWLEREAKDLLVKLFVREPEKRLG-VRG--DIRQHPLFREINWEELERKEI 647 Query: 2481 PPETRP 2498 P RP Sbjct: 648 DPPFRP 653
>Q5R8M1:STK38_PONPY Serine/threonine-protein kinase 38 - Pongo pygmaeus (Orangutan)| Length = 465 Score = 103 bits (258), Expect = 3e-21 Identities = 54/157 (34%), Positives = 96/157 (61%) Frame = +3 Query: 1416 LALQQGPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQA 1595 L L++ LGL++F LK +G G G V L + D+ ++A+K++ ++ ++++ +A Sbjct: 77 LRLKRTRLGLEDFESLKVIGRGAFGEVRLVQKKDTGHVYAMKILRKADMLEKEQVGHIRA 136 Query: 1596 EREILEMLDHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVA 1775 ER+IL D ++ ++ F L+ME+ PGGD+ L ++ + E +FY+A Sbjct: 137 ERDILVEADSLWVVKMFYSFQDKLNLYLIMEFLPGGDMMTLLMKKD--TLTEEETQFYIA 194 Query: 1776 EVLLALEYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 E +LA++ +H LG I+RD+KP+N+L+ GH+ LSDF Sbjct: 195 ETVLAIDSIHQLGFIHRDIKPDNLLLDSKGHVKLSDF 231 Score = 83.6 bits (205), Expect = 4e-15 Identities = 47/113 (41%), Positives = 63/113 (55%), Gaps = 2/113 (1%) Frame = +3 Query: 2139 SFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVS--QN 2312 S VGT +Y+APE+ G+ DWW+ GV +YE+L G PF ET V++ + Sbjct: 281 STVGTPDYIAPEVFMQTGYNKLCDWWSLGVIMYEMLIGYPPFCSETPQETYKKVMNWKET 340 Query: 2313 LRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPFFEGLNWALIR 2471 L FP +S AKDLI E E+R+G G EIK + FFEG++W IR Sbjct: 341 LTFPPEVPISEKAKDLILRFCC-EWEHRIGA-PGVEEIKSNSFFEGVDWEHIR 391
>Q91VJ4:STK38_MOUSE Serine/threonine-protein kinase 38 - Mus musculus (Mouse)| Length = 465 Score = 103 bits (258), Expect = 3e-21 Identities = 54/157 (34%), Positives = 96/157 (61%) Frame = +3 Query: 1416 LALQQGPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQA 1595 L L++ LGL++F LK +G G G V L + D+ ++A+K++ ++ ++++ +A Sbjct: 77 LRLKRTRLGLEDFESLKVIGRGAFGEVRLVQKKDTGHVYAMKILRKADMLEKEQVGHIRA 136 Query: 1596 EREILEMLDHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVA 1775 ER+IL D ++ ++ F L+ME+ PGGD+ L ++ + E +FY+A Sbjct: 137 ERDILVEADSLWVVKMFYSFQDKLNLYLIMEFLPGGDMMTLLMKKD--TLTEEETQFYIA 194 Query: 1776 EVLLALEYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 E +LA++ +H LG I+RD+KP+N+L+ GH+ LSDF Sbjct: 195 ETVLAIDSIHQLGFIHRDIKPDNLLLDSKGHVKLSDF 231 Score = 80.5 bits (197), Expect = 4e-14 Identities = 47/113 (41%), Positives = 62/113 (54%), Gaps = 2/113 (1%) Frame = +3 Query: 2139 SFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVS--QN 2312 S VGT +Y+APE+ G+ DWW+ GV +YE+L G PF ET V++ + Sbjct: 281 STVGTPDYIAPEVFMQTGYNKLCDWWSLGVIMYEMLIGYPPFCSETPQETYKKVMNWKET 340 Query: 2313 LRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPFFEGLNWALIR 2471 L FP VS AK LI E E+R+G G EIK + FFEG++W IR Sbjct: 341 LTFPPEVPVSEKAKGLILRFCC-EWEHRIGA-PGVEEIKNNLFFEGVDWEHIR 391
>Q15208:STK38_HUMAN Serine/threonine-protein kinase 38 - Homo sapiens (Human)| Length = 465 Score = 103 bits (258), Expect = 3e-21 Identities = 54/157 (34%), Positives = 96/157 (61%) Frame = +3 Query: 1416 LALQQGPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQA 1595 L L++ LGL++F LK +G G G V L + D+ ++A+K++ ++ ++++ +A Sbjct: 77 LRLKRTRLGLEDFESLKVIGRGAFGEVRLVQKKDTGHVYAMKILRKADMLEKEQVGHIRA 136 Query: 1596 EREILEMLDHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVA 1775 ER+IL D ++ ++ F L+ME+ PGGD+ L ++ + E +FY+A Sbjct: 137 ERDILVEADSLWVVKMFYSFQDKLNLYLIMEFLPGGDMMTLLMKKD--TLTEEETQFYIA 194 Query: 1776 EVLLALEYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 E +LA++ +H LG I+RD+KP+N+L+ GH+ LSDF Sbjct: 195 ETVLAIDSIHQLGFIHRDIKPDNLLLDSKGHVKLSDF 231 Score = 83.6 bits (205), Expect = 4e-15 Identities = 47/113 (41%), Positives = 63/113 (55%), Gaps = 2/113 (1%) Frame = +3 Query: 2139 SFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVS--QN 2312 S VGT +Y+APE+ G+ DWW+ GV +YE+L G PF ET V++ + Sbjct: 281 STVGTPDYIAPEVFMQTGYNKLCDWWSLGVIMYEMLIGYPPFCSETPQETYKKVMNWKET 340 Query: 2313 LRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPFFEGLNWALIR 2471 L FP +S AKDLI E E+R+G G EIK + FFEG++W IR Sbjct: 341 LTFPPEVPISEKAKDLILRFCC-EWEHRIGA-PGVEEIKSNSFFEGVDWEHIR 391
>Q7TSE6:ST38L_MOUSE Serine/threonine-protein kinase 38-like - Mus musculus (Mouse)| Length = 464 Score = 103 bits (258), Expect = 3e-21 Identities = 53/157 (33%), Positives = 95/157 (60%) Frame = +3 Query: 1416 LALQQGPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQA 1595 L L++ LGLD+F LK + G G V L + D+ ++A+K++ ++ ++++ +A Sbjct: 78 LRLKRTRLGLDDFESLKVIARGAFGEVRLVQKKDTGHIYAMKILRKADMLEKEQVAHIRA 137 Query: 1596 EREILEMLDHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVA 1775 ER+IL D ++ ++ F L+ME+ PGGD+ L ++ + E +FY++ Sbjct: 138 ERDILVEADGAWVVKMFYSFQDKRNLYLIMEFLPGGDMMTLLMKKD--TLTEEETQFYIS 195 Query: 1776 EVLLALEYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 E +LA++ +H LG I+RD+KP+N+L+ GH+ LSDF Sbjct: 196 ETVLAIDAIHQLGFIHRDVKPDNLLLDAKGHVKLSDF 232 Score = 93.6 bits (231), Expect = 4e-18 Identities = 55/127 (43%), Positives = 69/127 (54%), Gaps = 5/127 (3%) Frame = +3 Query: 2139 SFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVS--QN 2312 S VGT +Y+APE+ G+ DWW+ GV +YE+L G PF ET V+S + Sbjct: 282 STVGTPDYIAPEVFMQTGYNKLCDWWSLGVIMYEMLIGFPPFCSETPQETYRKVMSWKET 341 Query: 2313 LRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPFFEGLNWALIR---SVAP 2483 L FP VS AKDLI + ENR+G G EIK HPFFEG++W IR + P Sbjct: 342 LAFPPEVPVSEKAKDLILRFCT-DSENRIGN-GGVEEIKGHPFFEGVDWGHIRERPAAIP 399 Query: 2484 PETRPCD 2504 E R D Sbjct: 400 IEIRSID 406
>Q13237:KGP2_HUMAN cGMP-dependent protein kinase 2 - Homo sapiens (Human)| Length = 762 Score = 103 bits (258), Expect = 3e-21 Identities = 56/147 (38%), Positives = 89/147 (60%), Gaps = 1/147 (0%) Frame = +3 Query: 1449 NFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEMLDHP 1628 N ++ LG G G V L ++ + + FA+K + ++++ K+ +E+ ILE L P Sbjct: 452 NLEIIATLGVGGFGRVELVKVKNENVAFAMKCIRKKHIVDTKQQEHVYSEKRILEELCSP 511 Query: 1629 FLPTLYAHFTTDNLSCLVMEYCPGGDL-HVLRQRQPGRSFPEPSARFYVAEVLLALEYLH 1805 F+ LY F + +++E C GG+L +LR R SF EP+++F VA V A +YLH Sbjct: 512 FIVKLYRTFKDNKYVYMLLEACLGGELWSILRDRG---SFDEPTSKFCVACVTEAFDYLH 568 Query: 1806 MLGVIYRDLKPENILVRDDGHIMLSDF 1886 LG+IYRDLKPEN+++ +G++ L DF Sbjct: 569 RLGIIYRDLKPENLILDAEGYLKLVDF 595 Score = 82.8 bits (203), Expect = 7e-15 Identities = 45/118 (38%), Positives = 69/118 (58%), Gaps = 2/118 (1%) Frame = +3 Query: 2139 SFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQNLR 2318 +F GT EY+APE+I GH +VD+W+ G+ +YELL G PF G T N++ + + Sbjct: 609 TFCGTPEYVAPEVILNKGHDFSVDFWSLGILVYELLTGNPPFSGVDQMMTY-NLILKGIE 667 Query: 2319 FPDNP-VVSSNAKDLIRGLLVKEPENRLGTLR-GAAEIKQHPFFEGLNWALIRSVAPP 2486 D P ++ +DLIR L + P RLG L+ G +IK+H + G NW +++ + P Sbjct: 668 KMDFPRKITRRPEDLIRRLCRQNPTERLGNLKNGINDIKKHRWLNGFNWEGLKARSLP 725
>Q9V3I5:JIL1_DROME Chromosomal serine/threonine-protein kinase JIL-1 - Drosophila| melanogaster (Fruit fly) Length = 1207 Score = 103 bits (257), Expect = 4e-21 Identities = 71/207 (34%), Positives = 110/207 (53%), Gaps = 5/207 (2%) Frame = +3 Query: 1281 SQNSKSSISEYGCSTSISDESQFGLYGYNNRPHMVKDLCWITIRQLALQQGPLGLDNFRL 1460 S+ S S+ Y TS S + V DL + + L++F++ Sbjct: 207 SKASSSTTPSYAMPTSNSTPLDLDNEAHQRDLEAVTDLKYYV---KLYSDEAVSLNDFKI 263 Query: 1461 LKRLGCGDIGTVYLAELV---DSDCLFALKVMD-IEYLISRKKMLRAQAEREILEMLD-H 1625 ++ LG G G V+L + D+ L+A+KV++ I + RK + ER +LE + + Sbjct: 264 IRVLGTGAYGRVFLVRKLTRHDAGKLYAMKVLNKITVVQKRKTAEHTKTERVVLEAIQRN 323 Query: 1626 PFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALEYLH 1805 PFL +L+ F + + LV+++ GG+L +F E R Y+AEV+LALE LH Sbjct: 324 PFLVSLHYAFQSSSKLYLVLDFANGGELFT--HLYHSENFEESRVRVYIAEVVLALEQLH 381 Query: 1806 MLGVIYRDLKPENILVRDDGHIMLSDF 1886 LG+IYRD+K ENIL+ +GHI+LSDF Sbjct: 382 QLGIIYRDIKLENILLDGEGHIVLSDF 408 Score = 100 bits (249), Expect = 3e-20 Identities = 54/131 (41%), Positives = 84/131 (64%), Gaps = 7/131 (5%) Frame = +3 Query: 2103 QLVVEPTEARSNSFVGTHEYLAPEIIKGD--GHGSAVDWWTFGVFLYELLYGRTPFRGPG 2276 +++ E R++SF GT EY+APEII+ GH SAVDWW+ GV +ELL G +PF Sbjct: 412 KILTAENEYRAHSFCGTLEYMAPEIIRTGPPGHDSAVDWWSVGVLTFELLTGASPF-ATS 470 Query: 2277 NDETLANVVSQNLRFPDNPVV----SSNAKDLIRGLLVKEPENRL-GTLRGAAEIKQHPF 2441 + + + +S+ ++ + P++ S+NA+D + +L K P+ RL G R A+EIK+HPF Sbjct: 471 DGQVQQSEISRRIQ-KEQPMIPSSFSANARDFVLKMLEKNPKRRLGGNHRDASEIKEHPF 529 Query: 2442 FEGLNWALIRS 2474 F G+NW +R+ Sbjct: 530 FNGINWQELRT 540 Score = 47.0 bits (110), Expect = 4e-04 Identities = 43/169 (25%), Positives = 73/169 (43%), Gaps = 5/169 (2%) Frame = +3 Query: 1395 CWITIRQLALQQGPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRK 1574 C I LQ P D+ L R G GT + +D +F K++ + Sbjct: 604 CEIQYFNTGLQNIPCRPDDLELGTRTSNGAYGTCHFVVDSSTDLVFLAKIIPLS------ 657 Query: 1575 KMLRAQAEREI---LEMLDHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSF 1745 K ++ + I L+ +H + + + F + +VMEY G +L + Sbjct: 658 KFRPSEVDALISCALDTTNHKNIVSYHGTFREKCETWIVMEYLSGPELTASIRMD----- 712 Query: 1746 PEPSARFYVAEVLLALEYLHMLGVIYRDLKPENILV--RDDGHIMLSDF 1886 E S R ++++A+ ++H I+ DLKPENI+ R+D + L DF Sbjct: 713 -EDSCREIFLQLVMAVRHIHSKHFIHGDLKPENIMFENREDRTVKLIDF 760
>P28327:RK_BOVIN Rhodopsin kinase precursor - Bos taurus (Bovine)| Length = 561 Score = 102 bits (254), Expect = 9e-21 Identities = 58/156 (37%), Positives = 87/156 (55%), Gaps = 2/156 (1%) Frame = +3 Query: 1422 LQQGPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAER 1601 L+ P+G D F + LG G G V+ ++ + L+A K ++ + L RK A E+ Sbjct: 177 LEAQPMGEDWFLDFRVLGRGGFGEVFACQMKATGKLYACKKLNKKRLKKRKGYQGAMVEK 236 Query: 1602 EILEMLDHPFLPTLYAHFTTDNLSCLVMEYCPGGDL--HVLRQRQPGRSFPEPSARFYVA 1775 +IL + F+ +L F T CLVM GGD+ H+ + F EP A FY A Sbjct: 237 KILAKVHSRFIVSLAYAFETKTDLCLVMTIMNGGDIRYHIYNVDEDNPGFQEPRAIFYTA 296 Query: 1776 EVLLALEYLHMLGVIYRDLKPENILVRDDGHIMLSD 1883 +++ LE+LH +IYRDLKPEN+L+ DDG++ +SD Sbjct: 297 QIVSGLEHLHQRNIIYRDLKPENVLLDDDGNVRISD 332 Score = 78.2 bits (191), Expect = 2e-13 Identities = 42/128 (32%), Positives = 71/128 (55%), Gaps = 7/128 (5%) Frame = +3 Query: 2124 EARSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPG----NDETL 2291 + ++ + GT ++APE++ G+ + +VD++ GV LYE++ R PFR G N E Sbjct: 343 QTKTKGYAGTPGFMAPELLLGEEYDFSVDYFALGVTLYEMIAARGPFRARGEKVENKELK 402 Query: 2292 ANVVSQNLRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLRGAAE-IKQHPFFEGLNWALI 2468 V+ Q + +PD S +KD LL K+PE RLG G+ + ++ HP F ++W + Sbjct: 403 QRVLEQAVTYPDK--FSPASKDFCEALLQKDPEKRLGFRDGSCDGLRTHPLFRDISWRQL 460 Query: 2469 RS--VAPP 2486 + + PP Sbjct: 461 EAGMLTPP 468
>Q63433:PKN1_RAT Serine/threonine-protein kinase N1 - Rattus norvegicus (Rat)| Length = 946 Score = 102 bits (254), Expect = 9e-21 Identities = 60/158 (37%), Positives = 90/158 (56%), Gaps = 3/158 (1%) Frame = +3 Query: 1422 LQQGPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAER 1601 L++ PL L++F+ L LG G G V L+E S LFA+K + +++R ++ E+ Sbjct: 609 LRKSPLTLEDFKFLAVLGRGHFGKVLLSEFHSSGELFAIKALKKGDIVARDEVESLMCEK 668 Query: 1602 EILEMLD---HPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYV 1772 IL + HPFL L+ F T C VMEY GGDL + F EP A FY Sbjct: 669 RILATVTRAGHPFLVNLFGCFQTPEHVCFVMEYSAGGDLMLHIHSDV---FSEPRAGFYS 725 Query: 1773 AEVLLALEYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 A V+L L++LH ++YRDLK +N+L+ +G++ ++DF Sbjct: 726 ACVVLGLQFLHEHKIVYRDLKLDNLLLDTEGYVKIADF 763 Score = 101 bits (252), Expect = 1e-20 Identities = 52/122 (42%), Positives = 77/122 (63%), Gaps = 3/122 (2%) Frame = +3 Query: 2130 RSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQ 2309 R+++F GT E+LAPE++ + AVDWW GVFLYE+L G +PF G +E ++V+ Sbjct: 775 RTSTFCGTPEFLAPEVLTDTSYTRAVDWWGLGVFLYEMLVGESPFPGDDEEEVFDSIVND 834 Query: 2310 NLRFPDNPVVSSNAKDLIRGLLVKEPENRLG-TLRGAAEIKQHPFFEGLNW--ALIRSVA 2480 +R+P +S+ A ++R LL + PE RLG T R A ++K+ PFF L+W L R + Sbjct: 835 EVRYP--RFLSAEAIGIMRRLLRRNPERRLGSTERDAEDVKKQPFFRTLDWDALLARRLP 892 Query: 2481 PP 2486 PP Sbjct: 893 PP 894
>P70268:PKN1_MOUSE Serine/threonine-protein kinase N1 - Mus musculus (Mouse)| Length = 946 Score = 102 bits (253), Expect = 1e-20 Identities = 60/158 (37%), Positives = 90/158 (56%), Gaps = 3/158 (1%) Frame = +3 Query: 1422 LQQGPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAER 1601 L++ PL L++F+ L LG G G V L+E S LFA+K + +++R ++ E+ Sbjct: 609 LRKSPLTLEDFKFLAVLGRGHFGKVLLSEFRSSGELFAIKALKKGDIVARDEVESLMCEK 668 Query: 1602 EILEMLD---HPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYV 1772 IL + HPFL L+ F T C VMEY GGDL + F EP A FY Sbjct: 669 RILAAVTRAGHPFLVNLFGCFQTPEHVCFVMEYSAGGDLMLHIHSDV---FSEPRAVFYS 725 Query: 1773 AEVLLALEYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 A V+L L++LH ++YRDLK +N+L+ +G++ ++DF Sbjct: 726 ACVVLGLQFLHEHKIVYRDLKLDNLLLDTEGYVKIADF 763 Score = 99.8 bits (247), Expect = 6e-20 Identities = 51/122 (41%), Positives = 75/122 (61%), Gaps = 3/122 (2%) Frame = +3 Query: 2130 RSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQ 2309 R+++F GT E+LAPE++ + AVDWW GV LYE+L G +PF G +E ++V+ Sbjct: 775 RTSTFCGTPEFLAPEVLTDTSYTRAVDWWGLGVLLYEMLVGESPFPGDDEEEVFDSIVND 834 Query: 2310 NLRFPDNPVVSSNAKDLIRGLLVKEPENRLG-TLRGAAEIKQHPFFEGLNW--ALIRSVA 2480 +R+P +S+ A ++R LL + PE RLG T R A ++K+ PFF L W L R + Sbjct: 835 EVRYP--RFLSAEAIGIMRRLLRRNPERRLGSTERDAEDVKKQPFFRSLGWDVLLARRLP 892 Query: 2481 PP 2486 PP Sbjct: 893 PP 894
>P83099:KPC4_DROME Putative protein kinase C delta type homolog - Drosophila| melanogaster (Fruit fly) Length = 671 Score = 102 bits (253), Expect = 1e-20 Identities = 58/149 (38%), Positives = 90/149 (60%), Gaps = 1/149 (0%) Frame = +3 Query: 1443 LDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEM-L 1619 +D+F L LG G G V LAEL D+ +A+K + + ++ + ER++L + Sbjct: 340 VDDFHFLAVLGKGSFGKVLLAELRDTTYYYAIKCLKKDVVLEDDDVDSTLIERKVLALGT 399 Query: 1620 DHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALEY 1799 HP+L L+ F T++ VMEY GGDL + ++ GR F E ARFY AE++ L++ Sbjct: 400 KHPYLCHLFCTFQTESHLFFVMEYLNGGDL-MFHIQESGR-FSEERARFYGAEIISGLKF 457 Query: 1800 LHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 LH G+IYRDLK +N+L+ +GH+ ++DF Sbjct: 458 LHKKGIIYRDLKLDNVLLDYEGHVRIADF 486 Score = 97.1 bits (240), Expect = 4e-19 Identities = 49/121 (40%), Positives = 76/121 (62%), Gaps = 3/121 (2%) Frame = +3 Query: 2133 SNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQN 2312 ++SF GT +Y+APEIIKG+ + VDWW+FGV LYE+L G++PF G DE ++ ++ Sbjct: 499 ADSFCGTPDYMAPEIIKGEKYNQNVDWWSFGVLLYEMLIGQSPFSGCDEDELFWSICNEI 558 Query: 2313 LRFPDNPVVSSNAKDLIRGLLVKEPENRLGT-LRGAAEIKQHPFFEGLNWALI--RSVAP 2483 FP +S+ A +++GLL K+ R+G+ A +I H FF ++W L+ R + P Sbjct: 559 PWFP--VYISAEATGILKGLLEKDYTKRIGSQYSPAGDIADHIFFRPIDWGLLEKRQIEP 616 Query: 2484 P 2486 P Sbjct: 617 P 617
>P54265:DMPK_MOUSE Myotonin-protein kinase - Mus musculus (Mouse)| Length = 631 Score = 102 bits (253), Expect = 1e-20 Identities = 57/165 (34%), Positives = 97/165 (58%) Frame = +3 Query: 1392 LCWITIRQLALQQGPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISR 1571 L W+ L++ L D+F +LK +G G V + ++ + ++A+K+M+ ++ R Sbjct: 51 LQWVEPIAARLKEVRLQRDDFEILKVIGRGAFSEVAVVKMKQTGQVYAMKIMNKWDMLKR 110 Query: 1572 KKMLRAQAEREILEMLDHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPE 1751 ++ + ER++L D ++ L+ F +N LVMEY GGDL L + G P Sbjct: 111 GEVSCFREERDVLVKGDRRWITQLHFAFQDENYLYLVMEYYVGGDLLTLLSKF-GERIPA 169 Query: 1752 PSARFYVAEVLLALEYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 ARFY+AE+++A++ +H LG ++RD+KP+NIL+ GHI L+DF Sbjct: 170 EMARFYLAEIVMAIDSVHRLGYVHRDIKPDNILLDRCGHIRLADF 214 Score = 95.1 bits (235), Expect = 1e-18 Identities = 58/131 (44%), Positives = 75/131 (57%), Gaps = 10/131 (7%) Frame = +3 Query: 2130 RSNSFVGTHEYLAPEIIKGDG-------HGSAVDWWTFGVFLYELLYGRTPFRGPGNDET 2288 RS VGT +YL+PEI++ G +G DWW GVF YE+ YG+TPF ET Sbjct: 227 RSLVAVGTPDYLSPEILQAVGGGPGAGSYGPECDWWALGVFAYEMFYGQTPFYADSTAET 286 Query: 2289 LANVV--SQNLRFP-DNPVVSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPFFEGLNW 2459 A +V ++L P + VV A+DLIRGLL E RLG GA + ++HPFF GL+W Sbjct: 287 YAKIVHYREHLSLPLADTVVPEEAQDLIRGLLC-PAEIRLGR-GGAGDFQKHPFFFGLDW 344 Query: 2460 ALIRSVAPPET 2492 +R PP T Sbjct: 345 EGLRDSVPPFT 355
>Q16512:PKN1_HUMAN Serine/threonine-protein kinase N1 - Homo sapiens (Human)| Length = 942 Score = 101 bits (252), Expect = 1e-20 Identities = 60/158 (37%), Positives = 90/158 (56%), Gaps = 3/158 (1%) Frame = +3 Query: 1422 LQQGPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAER 1601 L++ PL L++F+ L LG G G V L+E S LFA+K + +++R ++ E+ Sbjct: 605 LRKSPLTLEDFKFLAVLGRGHFGKVLLSEFRPSGELFAIKALKKGDIVARDEVESLMCEK 664 Query: 1602 EILEMLD---HPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYV 1772 IL + HPFL L+ F T C VMEY GGDL + F EP A FY Sbjct: 665 RILAAVTSAGHPFLVNLFGCFQTPEHVCFVMEYSAGGDLMLHIHSDV---FSEPRAIFYS 721 Query: 1773 AEVLLALEYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 A V+L L++LH ++YRDLK +N+L+ +G++ ++DF Sbjct: 722 ACVVLGLQFLHEHKIVYRDLKLDNLLLDTEGYVKIADF 759 Score = 97.8 bits (242), Expect = 2e-19 Identities = 50/122 (40%), Positives = 75/122 (61%), Gaps = 3/122 (2%) Frame = +3 Query: 2130 RSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQ 2309 R+++F GT E+LAPE++ + AVDWW GV LYE+L G +PF G +E ++V+ Sbjct: 771 RTSTFCGTPEFLAPEVLTDTSYTRAVDWWGLGVLLYEMLVGESPFPGDDEEEVFDSIVND 830 Query: 2310 NLRFPDNPVVSSNAKDLIRGLLVKEPENRLGTL-RGAAEIKQHPFFEGLNW--ALIRSVA 2480 +R+P +S+ A ++R LL + PE RLG+ R A ++K+ PFF L W L R + Sbjct: 831 EVRYP--RFLSAEAIGIMRRLLRRNPERRLGSSERDAEDVKKQPFFRTLGWEALLARRLP 888 Query: 2481 PP 2486 PP Sbjct: 889 PP 890
>Q16974:KPC1_APLCA Calcium-dependent protein kinase C - Aplysia californica (California| sea hare) Length = 649 Score = 101 bits (252), Expect = 1e-20 Identities = 59/147 (40%), Positives = 88/147 (59%), Gaps = 1/147 (0%) Frame = +3 Query: 1449 NFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEMLDHP 1628 +F L LG G G V LAE +D L+A+K++ + +I + E+ +L + D P Sbjct: 319 DFNFLTVLGKGSFGKVVLAERKGTDELYAIKILKKDVIIQDDDVECTMIEKRVLALPDKP 378 Query: 1629 -FLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALEYLH 1805 FL L++ F T + VMEY GGDL + R +Q G+ F EP A FY AE+ + L YLH Sbjct: 379 PFLVQLHSCFQTMDRLYFVMEYVNGGDL-MYRIQQEGK-FKEPVAAFYAAEIAIGLFYLH 436 Query: 1806 MLGVIYRDLKPENILVRDDGHIMLSDF 1886 G++YRDLK +N+++ +GHI ++DF Sbjct: 437 TQGIVYRDLKLDNVMLDAEGHIKIADF 463 Score = 93.2 bits (230), Expect = 5e-18 Identities = 48/121 (39%), Positives = 67/121 (55%), Gaps = 3/121 (2%) Frame = +3 Query: 2133 SNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQN 2312 + +F GT +Y+APEI+ +G +VDWW +GV LYE+L G+ PF G +E ++ N Sbjct: 476 TRTFCGTPDYIAPEIVLYQPYGRSVDWWAYGVLLYEMLAGQPPFDGEDEEELFTSITDHN 535 Query: 2313 LRFPDNPVVSSNAKDLIRGLLVKEPENRLGT-LRGAAEIKQHPFFEGLNWALI--RSVAP 2483 + +P +S A L +GLL K P RLG G +IK FF + W I R V P Sbjct: 536 VSYP--KALSREAVSLCKGLLTKTPAKRLGCGPNGERDIKDRAFFRPIQWERIELREVQP 593 Query: 2484 P 2486 P Sbjct: 594 P 594
>Q15835:RK_HUMAN Rhodopsin kinase precursor - Homo sapiens (Human)| Length = 563 Score = 101 bits (251), Expect = 2e-20 Identities = 57/156 (36%), Positives = 87/156 (55%), Gaps = 2/156 (1%) Frame = +3 Query: 1422 LQQGPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAER 1601 L+ P+G D F + LG G G V ++ + L+A K ++ + L RK A E+ Sbjct: 180 LEAQPMGEDWFLDFRVLGKGGFGEVSACQMKATGKLYACKKLNKKRLKKRKGYQGAMVEK 239 Query: 1602 EILEMLDHPFLPTLYAHFTTDNLSCLVMEYCPGGDL--HVLRQRQPGRSFPEPSARFYVA 1775 +IL + F+ +L F T CLVM GGD+ H+ + FPEP A FY A Sbjct: 240 KILMKVHSRFIVSLAYAFETKADLCLVMTIMNGGDIRYHIYNVNEENPGFPEPRALFYTA 299 Query: 1776 EVLLALEYLHMLGVIYRDLKPENILVRDDGHIMLSD 1883 +++ LE+LH ++YRDLKPEN+L+ +DG++ +SD Sbjct: 300 QIICGLEHLHQRRIVYRDLKPENVLLDNDGNVRISD 335 Score = 80.9 bits (198), Expect = 3e-14 Identities = 42/128 (32%), Positives = 74/128 (57%), Gaps = 7/128 (5%) Frame = +3 Query: 2124 EARSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPG----NDETL 2291 ++++ + GT ++APE+++G+ + +VD++ GV LYE++ R PFR G N E Sbjct: 346 QSKTKGYAGTPGFMAPELLQGEEYDFSVDYFALGVTLYEMIAARGPFRARGEKVENKELK 405 Query: 2292 ANVVSQNLRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLRGAAE-IKQHPFFEGLNWALI 2468 ++S+ +++PD S +KD LL K+PE RLG + ++ HP F+ LNW + Sbjct: 406 HRIISEPVKYPDK--FSQASKDFCEALLEKDPEKRLGFRDETCDKLRAHPLFKDLNWRQL 463 Query: 2469 RS--VAPP 2486 + + PP Sbjct: 464 EAGMLMPP 471
>P28867:KPCD_MOUSE Protein kinase C delta type - Mus musculus (Mouse)| Length = 674 Score = 101 bits (251), Expect = 2e-20 Identities = 48/123 (39%), Positives = 77/123 (62%), Gaps = 2/123 (1%) Frame = +3 Query: 2124 EARSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVV 2303 E R+++F GT +Y+APEI++G + +VDWW+FGV LYE+L G++PF G DE ++ Sbjct: 500 EGRASTFCGTPDYIAPEILQGLKYSFSVDWWSFGVLLYEMLIGQSPFHGDDEDELFESIR 559 Query: 2304 SQNLRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPFFEGLNWALI--RSV 2477 +P ++ +KD++ L ++P+ RLG I+ HPFF+ +NW+L+ R V Sbjct: 560 VDTPHYP--RWITKESKDIMEKLFERDPDKRLGV---TGNIRIHPFFKTINWSLLEKRKV 614 Query: 2478 APP 2486 PP Sbjct: 615 EPP 617 Score = 94.4 bits (233), Expect = 2e-18 Identities = 57/149 (38%), Positives = 83/149 (55%), Gaps = 1/149 (0%) Frame = +3 Query: 1443 LDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEML- 1619 L+NF K LG G G V LAEL D FA+K + + ++ + E+ +L + Sbjct: 344 LENFTFQKVLGKGSFGKVLLAELKGKDKYFAIKCLKKDVVLIDDDVECTMVEKRVLALAW 403 Query: 1620 DHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALEY 1799 + PFL L F T + VME+ GGDL + + GR F A FY AE++ L++ Sbjct: 404 ESPFLTHLICTFQTKDHLFFVMEFLNGGDL-MFHIQDKGR-FELYRATFYAAEIICGLQF 461 Query: 1800 LHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 LH G+IYRDLK +N+++ DGHI ++DF Sbjct: 462 LHSKGIIYRDLKLDNVMLDRDGHIKIADF 490
>P05130:KPC1_DROME Protein kinase C, brain isozyme - Drosophila melanogaster (Fruit fly)| Length = 679 Score = 101 bits (251), Expect = 2e-20 Identities = 49/121 (40%), Positives = 72/121 (59%), Gaps = 3/121 (2%) Frame = +3 Query: 2133 SNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQN 2312 + +F GT +Y+APEII +G +VDWW +GV LYE+L G+ PF G +E A + N Sbjct: 506 TKTFCGTPDYIAPEIILYQPYGKSVDWWAYGVLLYEMLVGQPPFDGEDEEELFAAITDHN 565 Query: 2313 LRFPDNPVVSSNAKDLIRGLLVKEPENRLGT-LRGAAEIKQHPFFEGLNWALI--RSVAP 2483 + +P + +S AK+ +G L K+P RLG G +++ HPFF ++W I R V P Sbjct: 566 VSYPKS--LSKEAKEACKGFLTKQPNKRLGCGSSGEEDVRLHPFFRRIDWEKIENREVQP 623 Query: 2484 P 2486 P Sbjct: 624 P 624 Score = 97.4 bits (241), Expect = 3e-19 Identities = 57/147 (38%), Positives = 85/147 (57%), Gaps = 1/147 (0%) Frame = +3 Query: 1449 NFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEMLDHP 1628 +F +K LG G G V LAE S+ L+A+K++ + +I + E+ +L + + P Sbjct: 349 DFNFIKVLGKGSFGKVLLAERKGSEELYAIKILKKDVIIQDDDVECTMIEKRVLALGEKP 408 Query: 1629 -FLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALEYLH 1805 FL L++ F T + VMEY GGDL + Q Q F EP A FY AE+ L +LH Sbjct: 409 PFLVQLHSCFQTMDRLFFVMEYVNGGDL--MFQIQQFGKFKEPVAVFYAAEIAAGLFFLH 466 Query: 1806 MLGVIYRDLKPENILVRDDGHIMLSDF 1886 G++YRDLK +N+L+ DGH+ ++DF Sbjct: 467 TKGILYRDLKLDNVLLDADGHVKIADF 493
>P16912:KDC2_DROME Protein kinase DC2 - Drosophila melanogaster (Fruit fly)| Length = 583 Score = 101 bits (251), Expect = 2e-20 Identities = 54/148 (36%), Positives = 89/148 (60%) Frame = +3 Query: 1443 LDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEMLD 1622 LD+++++K +G G G V L S+ A+K++ + +I K++ + ER IL + Sbjct: 271 LDDYQIIKTVGTGTFGRVCLCRDRISEKYCAMKILAMTEVIRLKQIEHVKNERNILREIR 330 Query: 1623 HPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALEYL 1802 HPF+ +L D+ ++ +Y GG+L R G+ F ++ FY AE++ ALEYL Sbjct: 331 HPFVISLEWSTKDDSNLYMIFDYVCGGELFTYL-RNAGK-FTSQTSNFYAAEIVSALEYL 388 Query: 1803 HMLGVIYRDLKPENILVRDDGHIMLSDF 1886 H L ++YRDLKPEN+L+ DGH+ ++DF Sbjct: 389 HSLQIVYRDLKPENLLINRDGHLKITDF 416 Score = 86.3 bits (212), Expect = 6e-16 Identities = 45/111 (40%), Positives = 66/111 (59%), Gaps = 1/111 (0%) Frame = +3 Query: 2130 RSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQ 2309 R+ + GT EY+APEII+ GH AVDWW GV +YE+L G PF ++S Sbjct: 425 RTWTLCGTPEYIAPEIIQSKGHNKAVDWWALGVLIYEMLVGYPPFYDEQPFGIYEKILSG 484 Query: 2310 NLRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLR-GAAEIKQHPFFEGLNW 2459 + + + + AKDLI+ LLV + RLG ++ GA ++K+H +F+ LNW Sbjct: 485 KIEWERH--MDPIAKDLIKKLLVNDRTKRLGNMKNGADDVKRHRWFKHLNW 533
>P38679:COT1_NEUCR Serine/threonine-protein kinase cot-1 - Neurospora crassa| Length = 598 Score = 101 bits (251), Expect = 2e-20 Identities = 52/147 (35%), Positives = 87/147 (59%) Frame = +3 Query: 1446 DNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEMLDH 1625 +N++ +K +G G G V L + ++A+K + + + ++ +AER+IL D Sbjct: 212 ENYQTIKIIGKGAFGEVKLVQKKADGKVYAMKSLIKTEMFKKDQLAHVRAERDILAESDS 271 Query: 1626 PFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALEYLH 1805 P++ LY F N ++ME+ PGGDL + + F E RFY+AE++LA++ +H Sbjct: 272 PWVVKLYTTFQDANFLYMLMEFLPGGDLMTMLIKY--EIFSEDITRFYIAEIVLAIDAVH 329 Query: 1806 MLGVIYRDLKPENILVRDDGHIMLSDF 1886 LG I+RD+KP+NIL+ GH+ L+DF Sbjct: 330 KLGFIHRDIKPDNILLDRGGHVKLTDF 356 Score = 85.9 bits (211), Expect = 8e-16 Identities = 47/118 (39%), Positives = 68/118 (57%), Gaps = 2/118 (1%) Frame = +3 Query: 2139 SFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVS--QN 2312 S VGT +Y+APEI G G+ DWW+ G ++E L G PF + +T +V+ + Sbjct: 417 STVGTPDYIAPEIFTGHGYSFDCDWWSLGTIMFECLVGWPPFCAEDSHDTYRKIVNWRHS 476 Query: 2313 LRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPFFEGLNWALIRSVAPP 2486 L FPD+ + +A++LIR L+ ENRLG GA EIK H FF G+ + +R + P Sbjct: 477 LYFPDDITLGVDAENLIRSLIC-NTENRLGR-GGAHEIKSHAFFRGVEFDSLRRIRAP 532
>Q6DT37:MRCKG_HUMAN Serine/threonine-protein kinase MRCK gamma - Homo sapiens (Human)| Length = 1551 Score = 100 bits (250), Expect = 3e-20 Identities = 59/160 (36%), Positives = 96/160 (60%) Frame = +3 Query: 1407 IRQLALQQGPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLR 1586 +++L LQ+ D+F +LK +G G G V + D+ +FA+K++ ++ R + Sbjct: 61 VKELRLQR-----DDFEILKVIGRGAFGEVTVVRQRDTGQIFAMKMLHKWEMLKRAETAC 115 Query: 1587 AQAEREILEMLDHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARF 1766 + ER++L D ++ TL+ F + LVM+Y GGDL L R R PE A+F Sbjct: 116 FREERDVLVKGDSRWVTTLHYAFQDEEYLYLVMDYYAGGDLLTLLSRFEDRLPPE-LAQF 174 Query: 1767 YVAEVLLALEYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 Y+AE++LA+ LH LG ++RD+KP+N+L+ +GHI L+DF Sbjct: 175 YLAEMVLAIHSLHQLGYVHRDVKPDNVLLDVNGHIRLADF 214 Score = 91.3 bits (225), Expect = 2e-17 Identities = 59/132 (44%), Positives = 81/132 (61%), Gaps = 11/132 (8%) Frame = +3 Query: 2133 SNSFVGTHEYLAPEIIK----GDGH-GSAVDWWTFGVFLYELLYGRTPFRGPGNDETLAN 2297 S+ VGT +Y++PEI++ G GH G DWW+ GV YELL+G TPF ET Sbjct: 228 SSVAVGTPDYISPEILQAMEEGKGHYGPQCDWWSLGVCAYELLFGETPFYAESLVETYGK 287 Query: 2298 VVS--QNLRF-PDNPVVSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPFFEGLNW-AL 2465 +++ +L+F PD P V ++A+DLIR LL ++ E RLG G + + HPFFEG++W L Sbjct: 288 IMNHEDHLQFPPDVPDVPASAQDLIRQLLCRQ-EERLGR-GGLDDFRNHPFFEGVDWERL 345 Query: 2466 IRSVAP--PETR 2495 S AP PE R Sbjct: 346 ASSTAPYIPELR 357
>Q18846:KS6A2_CAEEL Putative ribosomal protein S6 kinase alpha-2 - Caenorhabditis elegans| Length = 772 Score = 100 bits (250), Expect = 3e-20 Identities = 63/157 (40%), Positives = 97/157 (61%), Gaps = 7/157 (4%) Frame = +3 Query: 1437 LGLDNFRLLKRLGCGDIGTVYLAELV---DSDCLFALKVMDIEYLISRKKMLR-AQAERE 1604 + ++NF LL+ LG G G V+L V D + ++A+KV+ +++++K L AER+ Sbjct: 12 VSMENFALLRVLGKGAYGKVFLVRKVGGKDHNTIYAMKVLRKTRVLTKQKTLEHTMAERQ 71 Query: 1605 ILEML-DHPFLPTLYAHFTTDNLSCLVMEYCPGGDL--HVLRQRQPGRSFPEPSARFYVA 1775 +LE L PFL L+ F TD +VMEY GG+L H+ + F +ARF +A Sbjct: 72 VLERLRGTPFLVNLFYAFQTDTKLHIVMEYVRGGELFTHLCSRGH----FDLEAARFVIA 127 Query: 1776 EVLLALEYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 E+++A++ LH VIYRDLK ENIL+ ++GH+ L+DF Sbjct: 128 ELVVAIDSLHQRKVIYRDLKLENILLDEEGHVKLTDF 164 Score = 77.4 bits (189), Expect = 3e-13 Identities = 45/124 (36%), Positives = 69/124 (55%), Gaps = 6/124 (4%) Frame = +3 Query: 2130 RSNSFVGTHEYLAPEIIKGD--GHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVV 2303 R+NS+ GT EY++PE+I G+ VDWW+ GV +ELL G +PF G + ++ Sbjct: 177 RANSYCGTIEYMSPEVINRPEGGYSDVVDWWSLGVISFELLTGCSPFTVDGAQNSSKDIA 236 Query: 2304 SQNL--RFPDNPVVSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPFFEGLNW--ALIR 2471 + + + P + +A+D I LL K+ E RLG G EIK H F ++W A+ R Sbjct: 237 KRIMTKKVPFPKTMDVDARDFIGQLLEKKLEKRLG-YNGVDEIKNHKFMSSIDWDAAVKR 295 Query: 2472 SVAP 2483 ++ P Sbjct: 296 TLKP 299 Score = 57.0 bits (136), Expect = 4e-07 Identities = 47/143 (32%), Positives = 70/143 (48%), Gaps = 4/143 (2%) Frame = +3 Query: 1470 LGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEMLD-HPFLPTLY 1646 LG G V E V FA+K+ +S+K +AQ E ILEM+ HP + L+ Sbjct: 388 LGKGAFSVVRRCERVVDGAQFAVKI------VSQKFASQAQREARILEMVQGHPNIVQLH 441 Query: 1647 AHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALEYLHMLGVIYR 1826 + LVME G +L L + + F E A + +++ A++YLH +++R Sbjct: 442 DVHSDPLHFYLVMEILTGNEL--LERIRKLERFTESEAADIMRQLVSAVKYLHDKRIVHR 499 Query: 1827 DLKPENIL---VRDDGHIMLSDF 1886 DLKPENIL + + L DF Sbjct: 500 DLKPENILFESIDSSARLRLVDF 522 Score = 47.8 bits (112), Expect = 3e-04 Identities = 30/93 (32%), Positives = 48/93 (51%), Gaps = 10/93 (10%) Frame = +3 Query: 2151 THEYLAPEIIK-GDG---HGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQNLR 2318 T +Y APE++ GD + D W+ GV L+ +L G+ PF E+ ++ + R Sbjct: 550 TLQYAAPEVLDVGDSQPEYNEQCDLWSLGVVLFTMLSGQVPFHARSRQESATEIMQRICR 609 Query: 2319 FPDN------PVVSSNAKDLIRGLLVKEPENRL 2399 + VS++AK+LI GLL +P+ RL Sbjct: 610 AEFSFTGDAWTNVSADAKNLITGLLTVDPKKRL 642
>Q9Z1M4:KS6B2_MOUSE Ribosomal protein S6 kinase beta-2 - Mus musculus (Mouse)| Length = 485 Score = 100 bits (249), Expect = 3e-20 Identities = 65/168 (38%), Positives = 93/168 (55%), Gaps = 6/168 (3%) Frame = +3 Query: 1401 ITIRQLALQQGP--LGLDNFRLLKRLGCGDIGTVYLAELVDSDCL---FALKVM-DIEYL 1562 + + + ++ GP +G F LL LG G G V+ V L +A+KV+ + + Sbjct: 48 VELTESSVNLGPERIGPHCFELLSVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIV 107 Query: 1563 ISRKKMLRAQAEREILEMLDHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRS 1742 S K +AER ILE + HPF+ L F T L++E GG+L +R+ Sbjct: 108 CSAKDTAHTRAERNILESVKHPFIVELAYAFQTGGKLYLILECLSGGELFTHLEREG--I 165 Query: 1743 FPEPSARFYVAEVLLALEYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 F E +A FY+AE+ LAL +LH G+IYRDLKPENI++ GHI L+DF Sbjct: 166 FLEDTACFYLAEITLALGHLHSHGIIYRDLKPENIMLSSQGHIKLTDF 213 Score = 96.7 bits (239), Expect = 5e-19 Identities = 48/123 (39%), Positives = 73/123 (59%), Gaps = 3/123 (2%) Frame = +3 Query: 2127 ARSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVS 2306 A +++F GT EY+APEI+ GH AVDWW+ G +Y++L G PF +T+ ++ Sbjct: 224 AITHTFCGTIEYMAPEILVRTGHNRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIK 283 Query: 2307 QNLRFPDNPVVSSNAKDLIRGLLVKEPENRL-GTLRGAAEIKQHPFFEGLNW--ALIRSV 2477 L P P ++ +A+DL + L + P R+ G L AA++++HPFF +NW L R V Sbjct: 284 GKLVLP--PYLTPDARDLAKKFLKRNPTQRIGGGLGDAADVQRHPFFRHINWDDLLARRV 341 Query: 2478 APP 2486 PP Sbjct: 342 DPP 344
>Q9UBS0:KS6B2_HUMAN Ribosomal protein S6 kinase beta-2 - Homo sapiens (Human)| Length = 482 Score = 100 bits (249), Expect = 3e-20 Identities = 64/168 (38%), Positives = 94/168 (55%), Gaps = 6/168 (3%) Frame = +3 Query: 1401 ITIRQLALQQGP--LGLDNFRLLKRLGCGDIGTVYLAELVDSDCL---FALKVMDIEYLI 1565 + + + ++ GP +G F LL+ LG G G V+ V L +A+KV+ ++ Sbjct: 48 VELTETSVNVGPERIGPHCFELLRVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIV 107 Query: 1566 -SRKKMLRAQAEREILEMLDHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRS 1742 + K +AER ILE + HPF+ L F T L++E GG+L +R+ Sbjct: 108 RNAKDTAHTRAERNILESVKHPFIVELAYAFQTGGKLYLILECLSGGELFTHLEREG--I 165 Query: 1743 FPEPSARFYVAEVLLALEYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 F E +A FY+AE+ LAL +LH G+IYRDLKPENI++ GHI L+DF Sbjct: 166 FLEDTACFYLAEITLALGHLHSQGIIYRDLKPENIMLSSQGHIKLTDF 213 Score = 99.0 bits (245), Expect = 1e-19 Identities = 48/127 (37%), Positives = 75/127 (59%), Gaps = 2/127 (1%) Frame = +3 Query: 2127 ARSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVS 2306 A +++F GT EY+APEI+ GH AVDWW+ G +Y++L G PF +T+ ++ Sbjct: 224 AVTHTFCGTIEYMAPEILVRSGHNRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIR 283 Query: 2307 QNLRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLRG-AAEIKQHPFFEGLNW-ALIRSVA 2480 L P P ++ +A+DL++ L + P R+G G AA++++HPFF +NW L+ Sbjct: 284 GKLALP--PYLTPDARDLVKKFLKRNPSQRIGGGPGDAADVQRHPFFRHMNWDDLLAWRV 341 Query: 2481 PPETRPC 2501 P RPC Sbjct: 342 DPPFRPC 348
>Q8BWW9:PKN2_MOUSE Serine/threonine-protein kinase N2 - Mus musculus (Mouse)| Length = 983 Score = 100 bits (248), Expect = 4e-20 Identities = 71/218 (32%), Positives = 109/218 (50%), Gaps = 3/218 (1%) Frame = +3 Query: 1242 RSSEWLTLEKGERSQNSKSSISEYGCSTSISDESQFGLYGYNNRPHMVKDLCWITIRQLA 1421 + SE + + +R+ S SEY S S S +G+ +++ A Sbjct: 600 QGSETVFNIENDRNNLRPKSKSEYELSIPDSGRSCWGVGELDDKR--------------A 645 Query: 1422 LQQGPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAER 1601 Q+ L +FR LG G G V LAE ++ +FA+K + +++R ++ E+ Sbjct: 646 QQRFQFSLQDFRCCAVLGRGHFGKVLLAEYKHTNEMFAIKALKKGDIVARDEVDSLMCEK 705 Query: 1602 EILEMLD---HPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYV 1772 I E ++ HPFL L+A F T C VMEY GGDL + F EP A FY Sbjct: 706 RIFETVNSVRHPFLVNLFACFQTKEHVCFVMEYAAGGDLMMHIHTDV---FSEPRAVFYA 762 Query: 1773 AEVLLALEYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 A V+L L+YLH ++YRDLK +N+L+ +G + ++DF Sbjct: 763 ACVVLGLQYLHEHKIVYRDLKLDNLLLDTEGFVKIADF 800 Score = 96.3 bits (238), Expect = 6e-19 Identities = 47/122 (38%), Positives = 76/122 (62%), Gaps = 3/122 (2%) Frame = +3 Query: 2130 RSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQ 2309 R+++F GT E+LAPE++ + AVDWW GV +YE+L G +PF G +E ++V+ Sbjct: 812 RTSTFCGTPEFLAPEVLTETSYTRAVDWWGLGVLIYEMLVGESPFPGDDEEEVFDSIVND 871 Query: 2310 NLRFPDNPVVSSNAKDLIRGLLVKEPENRLGT-LRGAAEIKQHPFFEGLNWALI--RSVA 2480 +R+P +S+ A ++R LL + PE RLG + A ++K+HPFF +W+ + + V Sbjct: 872 EVRYP--RFLSTEAISIMRRLLRRNPERRLGAGEKDAEDVKKHPFFRLTDWSALMDKKVK 929 Query: 2481 PP 2486 PP Sbjct: 930 PP 931
>Q96GX5:MASTL_HUMAN Microtubule-associated serine/threonine-protein kinase-like - Homo| sapiens (Human) Length = 879 Score = 100 bits (248), Expect = 4e-20 Identities = 59/151 (39%), Positives = 88/151 (58%) Frame = +3 Query: 1434 PLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILE 1613 P ++ F ++K + G G VYL + L+A+KV+ +I++ + QAER+ L Sbjct: 29 PPSIEEFSIVKPISRGAFGKVYLGQ--KGGKLYAVKVVKKADMINKNMTHQVQAERDALA 86 Query: 1614 MLDHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLAL 1793 + PF+ LY + N LVMEY GGD+ L F E A Y++EV LAL Sbjct: 87 LSKSPFIVHLYYSLQSANNVYLVMEYLIGGDVKSLLHIYG--YFDEEMAVKYISEVALAL 144 Query: 1794 EYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 +YLH G+I+RDLKP+N+L+ ++GHI L+DF Sbjct: 145 DYLHRHGIIHRDLKPDNMLISNEGHIKLTDF 175 Score = 78.6 bits (192), Expect = 1e-13 Identities = 39/115 (33%), Positives = 62/115 (53%), Gaps = 1/115 (0%) Frame = +3 Query: 2145 VGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQNLRFP 2324 +GT +YLAPE++ G HG AVDWW GV L+E L G PF + N++ +++ +P Sbjct: 739 LGTPDYLAPELLLGRAHGPAVDWWALGVCLFEFLTGIPPFNDETPQQVFQNILKRDIPWP 798 Query: 2325 D-NPVVSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPFFEGLNWALIRSVAPP 2486 + +S NA+ + LL + R G E+K+HP F ++W ++ P Sbjct: 799 EGEEKLSDNAQSAVEILLTIDDTKR----AGMKELKRHPLFSDVDWENLQHQTMP 849
>Q05655:KPCD_HUMAN Protein kinase C delta type - Homo sapiens (Human)| Length = 676 Score = 100 bits (248), Expect = 4e-20 Identities = 49/123 (39%), Positives = 76/123 (61%), Gaps = 2/123 (1%) Frame = +3 Query: 2124 EARSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVV 2303 E+R+++F GT +Y+APEI++G + +VDWW+FGV LYE+L G++PF G DE ++ Sbjct: 502 ESRASTFCGTPDYIAPEILQGLKYTFSVDWWSFGVLLYEMLIGQSPFHGDDEDELFESIR 561 Query: 2304 SQNLRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPFFEGLNWALI--RSV 2477 +P ++ +KD++ L +EP RLG IK HPFF+ +NW L+ R + Sbjct: 562 VDTPHYP--RWITKESKDILEKLFEREPTKRLGM---TGNIKIHPFFKTINWTLLEKRRL 616 Query: 2478 APP 2486 PP Sbjct: 617 EPP 619 Score = 85.5 bits (210), Expect = 1e-15 Identities = 54/149 (36%), Positives = 81/149 (54%), Gaps = 1/149 (0%) Frame = +3 Query: 1443 LDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEML- 1619 ++NF K LG G G V L EL A+K + + ++ + E+ +L + Sbjct: 346 INNFIFHKVLGKGSFGKVLLGELKGRGEYSAIKALKKDVVLIDDDVECTMVEKRVLTLAA 405 Query: 1620 DHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALEY 1799 ++PFL L F T + VME+ GGDL + + GR F A FY AE++ L++ Sbjct: 406 ENPFLTHLICTFQTKDHLFFVMEFLNGGDL-MYHIQDKGR-FELYRATFYAAEIMCGLQF 463 Query: 1800 LHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 LH G+IYRDLK +N+L+ DGHI ++DF Sbjct: 464 LHSKGIIYRDLKLDNVLLDRDGHIKIADF 492
>P05696:KPCA_RAT Protein kinase C alpha type - Rattus norvegicus (Rat)| Length = 672 Score = 100 bits (248), Expect = 4e-20 Identities = 58/149 (38%), Positives = 89/149 (59%), Gaps = 1/149 (0%) Frame = +3 Query: 1443 LDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEMLD 1622 L +F L LG G G V LA+ ++ L+A+K++ + +I + E+ +L +LD Sbjct: 336 LTDFNFLMVLGKGSFGKVMLADRKGTEELYAIKILKKDVVIQDDDVECTMVEKRVLALLD 395 Query: 1623 HP-FLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALEY 1799 P FL L++ F T + VMEY GGDL + +Q G+ F EP A FY AE+ + L + Sbjct: 396 KPPFLTQLHSCFQTVDRLYFVMEYVNGGDL-MYHIQQVGK-FKEPQAVFYAAEISIGLFF 453 Query: 1800 LHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 LH G+IYRDLK +N+++ +GHI ++DF Sbjct: 454 LHKRGIIYRDLKLDNVMLDSEGHIKIADF 482 Score = 97.1 bits (240), Expect = 4e-19 Identities = 45/121 (37%), Positives = 72/121 (59%), Gaps = 3/121 (2%) Frame = +3 Query: 2133 SNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQN 2312 + +F GT +Y+APEII +G +VDWW +GV LYE+L G+ PF G DE +++ N Sbjct: 495 TRTFCGTPDYIAPEIIAYQPYGKSVDWWAYGVLLYEMLAGQPPFDGEDEDELFQSIMEHN 554 Query: 2313 LRFPDNPVVSSNAKDLIRGLLVKEPENRLGT-LRGAAEIKQHPFFEGLNWALI--RSVAP 2483 + +P + +S A + +GL+ K P RLG G ++++H FF ++W + R + P Sbjct: 555 VSYPKS--LSKEAVSICKGLMTKHPAKRLGCGPEGERDVREHAFFRRIDWEKLENREIQP 612 Query: 2484 P 2486 P Sbjct: 613 P 613
>P20444:KPCA_MOUSE Protein kinase C alpha type - Mus musculus (Mouse)| Length = 672 Score = 100 bits (248), Expect = 4e-20 Identities = 58/149 (38%), Positives = 88/149 (59%), Gaps = 1/149 (0%) Frame = +3 Query: 1443 LDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEMLD 1622 L +F L LG G G V LA+ ++ L+A+K++ + +I + E+ +L +LD Sbjct: 336 LTDFNFLMVLGKGSFGKVMLADRKGTEELYAIKILKKDVVIQDDDVECTMVEKRVLALLD 395 Query: 1623 HP-FLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALEY 1799 P FL L++ F T + VMEY GGDL + +Q G+ F EP A FY AE+ + L + Sbjct: 396 KPPFLTQLHSCFQTVDRLYFVMEYVNGGDL-MYHIQQVGK-FKEPQAVFYAAEISIGLFF 453 Query: 1800 LHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 LH G+IYRDLK N+++ +GHI ++DF Sbjct: 454 LHKRGIIYRDLKLNNVMLNSEGHIKIADF 482 Score = 97.8 bits (242), Expect = 2e-19 Identities = 45/121 (37%), Positives = 73/121 (60%), Gaps = 3/121 (2%) Frame = +3 Query: 2133 SNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQN 2312 + +F GT +Y+APEII +G +VDWW +GV LYE+L G+ PF G DE +++ N Sbjct: 495 TRTFCGTPDYIAPEIIAYQPYGKSVDWWAYGVLLYEMLAGQPPFDGEDEDELFQSIMEHN 554 Query: 2313 LRFPDNPVVSSNAKDLIRGLLVKEPENRLGT-LRGAAEIKQHPFFEGLNWALI--RSVAP 2483 + +P + +S A + +GL+ K+P RLG G ++++H FF ++W + R + P Sbjct: 555 VSYPKS--LSKEAVSICKGLMTKQPAKRLGCGPEGERDVREHAFFRRIDWEKLENREIQP 612 Query: 2484 P 2486 P Sbjct: 613 P 613
>P17252:KPCA_HUMAN Protein kinase C alpha type - Homo sapiens (Human)| Length = 672 Score = 100 bits (248), Expect = 4e-20 Identities = 58/149 (38%), Positives = 89/149 (59%), Gaps = 1/149 (0%) Frame = +3 Query: 1443 LDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEMLD 1622 L +F L LG G G V LA+ ++ L+A+K++ + +I + E+ +L +LD Sbjct: 336 LTDFNFLMVLGKGSFGKVMLADRKGTEELYAIKILKKDVVIQDDDVECTMVEKRVLALLD 395 Query: 1623 HP-FLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALEY 1799 P FL L++ F T + VMEY GGDL + +Q G+ F EP A FY AE+ + L + Sbjct: 396 KPPFLTQLHSCFQTVDRLYFVMEYVNGGDL-MYHIQQVGK-FKEPQAVFYAAEISIGLFF 453 Query: 1800 LHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 LH G+IYRDLK +N+++ +GHI ++DF Sbjct: 454 LHKRGIIYRDLKLDNVMLDSEGHIKIADF 482 Score = 97.1 bits (240), Expect = 4e-19 Identities = 45/121 (37%), Positives = 72/121 (59%), Gaps = 3/121 (2%) Frame = +3 Query: 2133 SNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQN 2312 + +F GT +Y+APEII +G +VDWW +GV LYE+L G+ PF G DE +++ N Sbjct: 495 TRTFCGTPDYIAPEIIAYQPYGKSVDWWAYGVLLYEMLAGQPPFDGEDEDELFQSIMEHN 554 Query: 2313 LRFPDNPVVSSNAKDLIRGLLVKEPENRLGT-LRGAAEIKQHPFFEGLNWALI--RSVAP 2483 + +P + +S A + +GL+ K P RLG G ++++H FF ++W + R + P Sbjct: 555 VSYPKS--LSKEAVSICKGLMTKHPAKRLGCGPEGERDVREHAFFRRIDWEKLENREIQP 612 Query: 2484 P 2486 P Sbjct: 613 P 613
>P04409:KPCA_BOVIN Protein kinase C alpha type - Bos taurus (Bovine)| Length = 672 Score = 100 bits (248), Expect = 4e-20 Identities = 58/149 (38%), Positives = 89/149 (59%), Gaps = 1/149 (0%) Frame = +3 Query: 1443 LDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEMLD 1622 L +F L LG G G V LA+ ++ L+A+K++ + +I + E+ +L +LD Sbjct: 336 LTDFNFLMVLGKGSFGKVMLADRKGTEELYAIKILKKDVVIQDDDVECTMVEKRVLALLD 395 Query: 1623 HP-FLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALEY 1799 P FL L++ F T + VMEY GGDL + +Q G+ F EP A FY AE+ + L + Sbjct: 396 KPPFLTQLHSCFQTVDRLYFVMEYVNGGDL-MYHIQQVGK-FKEPQAVFYAAEISIGLFF 453 Query: 1800 LHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 LH G+IYRDLK +N+++ +GHI ++DF Sbjct: 454 LHKRGIIYRDLKLDNVMLDSEGHIKIADF 482 Score = 96.7 bits (239), Expect = 5e-19 Identities = 45/121 (37%), Positives = 72/121 (59%), Gaps = 3/121 (2%) Frame = +3 Query: 2133 SNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQN 2312 + +F GT +Y+APEII +G +VDWW +GV LYE+L G+ PF G DE +++ N Sbjct: 495 TRTFCGTPDYIAPEIIAYQPYGKSVDWWAYGVLLYEMLAGQPPFDGEDEDELFQSIMEHN 554 Query: 2313 LRFPDNPVVSSNAKDLIRGLLVKEPENRLGT-LRGAAEIKQHPFFEGLNWALI--RSVAP 2483 + +P + +S A + +GL+ K P RLG G ++++H FF ++W + R + P Sbjct: 555 VSYPKS--LSKEAVSICKGLMTKHPGKRLGCGPEGERDVREHAFFRRIDWEKLENREIQP 612 Query: 2484 P 2486 P Sbjct: 613 P 613
>Q16513:PKN2_HUMAN Serine/threonine-protein kinase N2 - Homo sapiens (Human)| Length = 984 Score = 99.8 bits (247), Expect = 6e-20 Identities = 59/157 (37%), Positives = 88/157 (56%), Gaps = 3/157 (1%) Frame = +3 Query: 1425 QQGPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAERE 1604 Q+ L +FR LG G G V LAE +++ +FA+K + +++R ++ E+ Sbjct: 648 QRFQFNLQDFRCCAVLGRGHFGKVLLAEYKNTNEMFAIKALKKGDIVARDEVDSLMCEKR 707 Query: 1605 ILEMLD---HPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVA 1775 I E ++ HPFL L+A F T C VMEY GGDL + F EP A FY A Sbjct: 708 IFETVNSVRHPFLVNLFACFQTKEHVCFVMEYAAGGDLMMHIHTDV---FSEPRAVFYAA 764 Query: 1776 EVLLALEYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 V+L L+YLH ++YRDLK +N+L+ +G + ++DF Sbjct: 765 CVVLGLQYLHEHKIVYRDLKLDNLLLDTEGFVKIADF 801 Score = 97.8 bits (242), Expect = 2e-19 Identities = 47/122 (38%), Positives = 78/122 (63%), Gaps = 3/122 (2%) Frame = +3 Query: 2130 RSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQ 2309 R+++F GT E+LAPE++ + AVDWW GV +YE+L G +PF G +E ++V+ Sbjct: 813 RTSTFCGTPEFLAPEVLTETSYTRAVDWWGLGVLIYEMLVGESPFPGDDEEEVFDSIVND 872 Query: 2310 NLRFPDNPVVSSNAKDLIRGLLVKEPENRLG-TLRGAAEIKQHPFFEGLNWALI--RSVA 2480 +R+P +S+ A ++R LL + PE RLG + + A ++K+HPFF ++W+ + + V Sbjct: 873 EVRYP--RFLSTEAISIMRRLLRRNPERRLGASEKDAEDVKKHPFFRLIDWSALMDKKVK 930 Query: 2481 PP 2486 PP Sbjct: 931 PP 932
>Q25378:KPC1_LYTPI Protein kinase C - Lytechinus pictus (Painted sea urchin)| Length = 658 Score = 99.8 bits (247), Expect = 6e-20 Identities = 61/153 (39%), Positives = 86/153 (56%), Gaps = 1/153 (0%) Frame = +3 Query: 1431 GPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREIL 1610 G + +F L LG G G V LAE +D L+A+K++ + +I + E+ +L Sbjct: 318 GVVRASDFNFLSVLGKGSFGKVMLAEKKGTDELYAIKILKKDVIIQDDDVECTMTEKRVL 377 Query: 1611 EMLDHP-FLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLL 1787 + P FL L++ F T + VME+ GGDL + Q Q F EP A FY AE+ + Sbjct: 378 GLPSKPAFLTALHSCFQTMDRLFFVMEFVNGGDL--MFQIQKVGKFREPHAVFYAAEIAV 435 Query: 1788 ALEYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 L YLH GVIYRDLK +N+LV +GHI ++DF Sbjct: 436 GLFYLHSQGVIYRDLKLDNVLVDAEGHIKIADF 468 Score = 91.7 bits (226), Expect = 2e-17 Identities = 45/121 (37%), Positives = 70/121 (57%), Gaps = 3/121 (2%) Frame = +3 Query: 2133 SNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQN 2312 + +F GT +Y+APEI+ +G AVDWW FGV LYE+L G+ PF G DE +++ Sbjct: 481 TRTFCGTPDYIAPEIVAYQPYGKAVDWWAFGVLLYEMLAGQPPFDGEDEDELFQSIMEHV 540 Query: 2313 LRFPDNPVVSSNAKDLIRGLLVKEPENRLGT-LRGAAEIKQHPFFEGLNWALI--RSVAP 2483 +P + +S + + +G L K P RLG+ G +I++H FF ++W + R + P Sbjct: 541 PSYPKS--MSRESVTMCKGFLTKHPGKRLGSGPTGEQDIREHQFFRRIDWEKLANREIQP 598 Query: 2484 P 2486 P Sbjct: 599 P 599
>Q09013:DMPK_HUMAN Myotonin-protein kinase - Homo sapiens (Human)| Length = 639 Score = 99.8 bits (247), Expect = 6e-20 Identities = 55/155 (35%), Positives = 94/155 (60%) Frame = +3 Query: 1422 LQQGPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAER 1601 L++ L D+F +LK +G G V + ++ + ++A+K+M+ ++ R ++ + ER Sbjct: 71 LKEVRLQRDDFEILKVIGRGAFSEVAVVKMKQTGQVYAMKIMNKWDMLKRGEVSCFREER 130 Query: 1602 EILEMLDHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEV 1781 ++L D ++ L+ F +N LVMEY GGDL L + G P ARFY+AE+ Sbjct: 131 DVLVNGDRRWITQLHFAFQDENYLYLVMEYYVGGDLLTLLSKF-GERIPAEMARFYLAEI 189 Query: 1782 LLALEYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 ++A++ +H LG ++RD+KP+NIL+ GHI L+DF Sbjct: 190 VMAIDSVHRLGYVHRDIKPDNILLDRCGHIRLADF 224 Score = 88.6 bits (218), Expect = 1e-16 Identities = 54/131 (41%), Positives = 71/131 (54%), Gaps = 10/131 (7%) Frame = +3 Query: 2130 RSNSFVGTHEYLAPEIIKGDG-------HGSAVDWWTFGVFLYELLYGRTPFRGPGNDET 2288 RS VGT +YL+PEI++ G +G DWW GVF YE+ YG+TPF ET Sbjct: 237 RSLVAVGTPDYLSPEILQAVGGGPGTGSYGPECDWWALGVFAYEMFYGQTPFYADSTAET 296 Query: 2289 LANVV--SQNLRFP-DNPVVSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPFFEGLNW 2459 +V ++L P + V A+D I+ LL PE RLG GA + + HPFF GL+W Sbjct: 297 YGKIVHYKEHLSLPLVDEGVPEEARDFIQRLLC-PPETRLGR-GGAGDFRTHPFFFGLDW 354 Query: 2460 ALIRSVAPPET 2492 +R PP T Sbjct: 355 DGLRDSVPPFT 365
>Q8TFG6:PPK18_SCHPO Serine/threonine-protein kinase ppk18 - Schizosaccharomyces pombe| (Fission yeast) Length = 1316 Score = 99.4 bits (246), Expect = 7e-20 Identities = 56/154 (36%), Positives = 92/154 (59%), Gaps = 1/154 (0%) Frame = +3 Query: 1428 QGPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREI 1607 +G + ++ ++K + G GTVYL+ + ++A+KV+ +IS+ ++ +AER + Sbjct: 556 KGTPSIQDYEIIKPISKGTFGTVYLSRKNTTGEIYAIKVLRKVDMISKNQVANVKAERAV 615 Query: 1608 LEMLDHP-FLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVL 1784 L + F+ LY F + + LVME+ GGD L + + PE A+ Y+AEV Sbjct: 616 LMAQEESAFVAKLYYAFQSRDYLYLVMEFMNGGDCASLLKSL--YTIPESWAKIYIAEVA 673 Query: 1785 LALEYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 L LE+LH LG+I+RD+KP+NIL+ GH+ L+DF Sbjct: 674 LGLEHLHRLGIIHRDIKPDNILMSITGHLKLADF 707 Score = 97.8 bits (242), Expect = 2e-19 Identities = 50/117 (42%), Positives = 65/117 (55%), Gaps = 2/117 (1%) Frame = +3 Query: 2142 FVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQNLRF 2321 FVGT +YLAPE ++G VDWW G L+E L+G PF ++ N+++ N+ + Sbjct: 831 FVGTPDYLAPETLRGSTQDDMVDWWALGCVLFEFLFGYPPFHAETPEKVFENILANNIAW 890 Query: 2322 PDNPV--VSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPFFEGLNWALIRSVAPP 2486 PD + S A DLI G L PE RLG EIK+HPFF G+NW I S P Sbjct: 891 PDLEMYPCSEEALDLINGFLQPNPERRLG-FSDINEIKEHPFFNGINWDDIFSHEAP 946
>P10102:KPCA_RABIT Protein kinase C alpha type - Oryctolagus cuniculus (Rabbit)| Length = 672 Score = 99.4 bits (246), Expect = 7e-20 Identities = 57/149 (38%), Positives = 89/149 (59%), Gaps = 1/149 (0%) Frame = +3 Query: 1443 LDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEMLD 1622 L +F L LG G G V LA+ ++ L+A+K++ + +I + E+ +L ++D Sbjct: 336 LTDFNFLMVLGKGSFGKVMLADRKGTEELYAIKILKKDVVIQDDDVECTMVEKRVLALMD 395 Query: 1623 HP-FLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALEY 1799 P FL L++ F T + VMEY GGDL + +Q G+ F EP A FY AE+ + L + Sbjct: 396 KPPFLTQLHSCFQTVDRLYFVMEYVNGGDL-MYHIQQVGK-FKEPQAVFYAAEISIGLFF 453 Query: 1800 LHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 LH G+IYRDLK +N+++ +GHI ++DF Sbjct: 454 LHKRGIIYRDLKLDNVMLDSEGHIKIADF 482 Score = 97.1 bits (240), Expect = 4e-19 Identities = 45/121 (37%), Positives = 72/121 (59%), Gaps = 3/121 (2%) Frame = +3 Query: 2133 SNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQN 2312 + +F GT +Y+APEII +G +VDWW +GV LYE+L G+ PF G DE +++ N Sbjct: 495 TRTFCGTPDYIAPEIIAYQPYGKSVDWWAYGVLLYEMLAGQPPFDGEDEDELFQSIMEHN 554 Query: 2313 LRFPDNPVVSSNAKDLIRGLLVKEPENRLGT-LRGAAEIKQHPFFEGLNWALI--RSVAP 2483 + +P + +S A + +GL+ K P RLG G ++++H FF ++W + R + P Sbjct: 555 VSYPKS--LSKEAVSICKGLMTKHPAKRLGCGPEGERDVREHAFFRRIDWEKLENREIQP 612 Query: 2484 P 2486 P Sbjct: 613 P 613
>P90980:KPC2_CAEEL Protein kinase C-like 2 - Caenorhabditis elegans| Length = 682 Score = 99.4 bits (246), Expect = 7e-20 Identities = 49/127 (38%), Positives = 73/127 (57%), Gaps = 6/127 (4%) Frame = +3 Query: 2124 EARSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVV 2303 +A + +F GT +Y+APEII +G +VDWW +GV L+E+L G+ PF G DE + Sbjct: 501 DATTKTFCGTPDYIAPEIILYQPYGKSVDWWAYGVLLFEMLAGQPPFDGEDEDELFTAIT 560 Query: 2304 SQNLRFPDNPVVSSNAKDLIRGLLVKEPENRLGTL----RGAAEIKQHPFFEGLNWALI- 2468 N+ +P + +S A L + LL+K P RLG + +IK+HPFF ++W I Sbjct: 561 EHNVSYPKS--LSKEAVSLCKALLIKNPSKRLGCTGDDESASRDIKEHPFFRRIDWFKIE 618 Query: 2469 -RSVAPP 2486 R + PP Sbjct: 619 TRQIQPP 625 Score = 95.9 bits (237), Expect = 8e-19 Identities = 60/160 (37%), Positives = 87/160 (54%), Gaps = 9/160 (5%) Frame = +3 Query: 1434 PLGLDNFRLLKR--------LGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRA 1589 PLG N ++K LG G G V L E + LFA+KV+ + +I + Sbjct: 334 PLGSSNHNVIKASDFNFLTVLGKGSFGKVLLGEQKTTKELFAIKVLKKDVIIQDDDVECT 393 Query: 1590 QAEREILEMLDHP-FLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARF 1766 E+ +L + + P FL L++ F T + VME+ GGDL + Q Q F EP A F Sbjct: 394 MTEKRVLALPEKPSFLVALHSCFQTMDRLYFVMEFVNGGDL--MYQIQQVGKFKEPVAVF 451 Query: 1767 YVAEVLLALEYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 Y AE+ + L +LH G+IYRDLK +N+++ DGHI ++DF Sbjct: 452 YAAEIAVGLFFLHSKGIIYRDLKLDNVMLERDGHIKITDF 491
>P34722:KPC1_CAEEL Protein kinase C-like 1 - Caenorhabditis elegans| Length = 704 Score = 99.4 bits (246), Expect = 7e-20 Identities = 58/149 (38%), Positives = 82/149 (55%), Gaps = 1/149 (0%) Frame = +3 Query: 1443 LDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEMLD 1622 L +F LLK LG G G V L EL + +A+K + + ++ ER +L + Sbjct: 372 LPHFNLLKVLGKGSFGKVMLVELKGKNEFYAMKCLKKDVILEDDDTECTYIERRVLILAS 431 Query: 1623 H-PFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALEY 1799 PFL L+ F T+ VMEY GGDL + Q + F E RFY E+++AL++ Sbjct: 432 QCPFLCQLFCSFQTNEYLFFVMEYLNGGDL--MHHIQQIKKFDEARTRFYACEIVVALQF 489 Query: 1800 LHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 LH +IYRDLK +N+L+ DGHI L+DF Sbjct: 490 LHTNNIIYRDLKLDNVLLDCDGHIKLADF 518 Score = 92.4 bits (228), Expect = 9e-18 Identities = 47/121 (38%), Positives = 71/121 (58%), Gaps = 3/121 (2%) Frame = +3 Query: 2133 SNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQN 2312 +++F GT +Y++PEIIKG + AVD+W+FGV +YE+L G++PF G G DE +++++ Sbjct: 532 ASTFCGTPDYISPEIIKGQLYNEAVDFWSFGVLMYEMLVGQSPFHGEGEDELFDSILNER 591 Query: 2313 LRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLR-GAAEIKQHPFFEGLNWALI--RSVAP 2483 FP +S A + L + P RLG I+QH FF G++W R V P Sbjct: 592 PYFP--KTISKEAAKCLSALFDRNPNTRLGMPECPDGPIRQHCFFRGVDWKRFENRQVPP 649 Query: 2484 P 2486 P Sbjct: 650 P 650
>Q622Z7:GRK1_CAEBR G protein-coupled receptor kinase 1 - Caenorhabditis briggsae| Length = 640 Score = 99.4 bits (246), Expect = 7e-20 Identities = 57/155 (36%), Positives = 90/155 (58%), Gaps = 1/155 (0%) Frame = +3 Query: 1422 LQQGPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAER 1601 L++ P+ FRL + LG G G V ++ S ++ALK ++ + + R + E+ Sbjct: 192 LEKRPVDKHTFRLYRVLGKGGFGEVCACQVRASGKMYALKKLEKKRVKKRHAETLSLNEK 251 Query: 1602 EILEMLDHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHV-LRQRQPGRSFPEPSARFYVAE 1778 +IL+ ++ PF+ +L + T + CLV+ GGDL L PG F E +FY AE Sbjct: 252 QILQKVNSPFVVSLAYAYETKDALCLVLTLMNGGDLKFHLYNLMPG-GFDEKRVQFYAAE 310 Query: 1779 VLLALEYLHMLGVIYRDLKPENILVRDDGHIMLSD 1883 + L L++LH+ ++YRDLKPENIL+ D GH+ +SD Sbjct: 311 ITLGLQHLHLEHILYRDLKPENILLDDFGHVRISD 345 Score = 75.9 bits (185), Expect = 9e-13 Identities = 50/132 (37%), Positives = 67/132 (50%), Gaps = 9/132 (6%) Frame = +3 Query: 2115 EPTEARSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLA 2294 EP + R VGT Y+APEI+K + + VDWW G +YE++ G+ PFR ++ Sbjct: 356 EPIKGR----VGTVGYMAPEIVKNERYTYGVDWWGVGCLIYEMIEGKAPFR-QRKEKVKR 410 Query: 2295 NVVSQNLRFPD---NPVVSSNAKDLIRGLLVKEPENRLGTLR------GAAEIKQHPFFE 2447 V + +R + S A+ L RGLL KEP RLG R GA EI+ HPFF Sbjct: 411 EEVERRVREDQEKYSEKFSEAARTLCRGLLHKEPGFRLGCRRVGKPEDGAEEIRAHPFFN 470 Query: 2448 GLNWALIRSVAP 2483 + A R P Sbjct: 471 TADTATGREPVP 482
>Q9NY57:ST32B_HUMAN Serine/threonine-protein kinase 32B - Homo sapiens (Human)| Length = 414 Score = 99.0 bits (245), Expect = 1e-19 Identities = 50/151 (33%), Positives = 90/151 (59%) Frame = +3 Query: 1437 LGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEM 1616 + D+F++L+ +G G G V + + D+ ++A+K M+ + I R ++ E +I++ Sbjct: 18 VNFDHFQILRAIGKGSFGKVCIVQKRDTKKMYAMKYMNKQKCIERDEVRNVFRELQIMQG 77 Query: 1617 LDHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALE 1796 L+HPFL L+ F + +V++ GGDL Q+ F E + + Y+ E+ LALE Sbjct: 78 LEHPFLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQNV--HFTEGTVKLYICELALALE 135 Query: 1797 YLHMLGVIYRDLKPENILVRDDGHIMLSDFD 1889 YL +I+RD+KP+NIL+ + GH+ ++DF+ Sbjct: 136 YLQRYHIIHRDIKPDNILLDEHGHVHITDFN 166 Score = 60.5 bits (145), Expect = 4e-08 Identities = 38/118 (32%), Positives = 59/118 (50%), Gaps = 8/118 (6%) Frame = +3 Query: 2130 RSNSFVGTHEYLAPEII-----KGDGHGSAVDWWTFGVFLYELLYGRTPFR---GPGNDE 2285 R++S GT Y+APE+ +G G+ VDWW+ G+ YELL G P+ DE Sbjct: 176 RASSMAGTKPYMAPEVFQVYMDRGPGYSYPVDWWSLGITAYELLRGWRPYEIHSVTPIDE 235 Query: 2286 TLANVVSQNLRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPFFEGLNW 2459 L + + + A L+R LL K+PE+R+ +L +I+ P+ +NW Sbjct: 236 ILNMFKVERVHYSSTWCKGMVA--LLRKLLTKDPESRVSSLH---DIQSVPYLADMNW 288
>Q9JJX8:ST32B_MOUSE Serine/threonine-protein kinase 32B - Mus musculus (Mouse)| Length = 414 Score = 98.6 bits (244), Expect = 1e-19 Identities = 49/151 (32%), Positives = 90/151 (59%) Frame = +3 Query: 1437 LGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEM 1616 + D+F++L+ +G G G V + + D+ ++A+K M+ + + R ++ E +I++ Sbjct: 18 VNFDHFQILRAIGKGSFGKVCIVQKRDTKKMYAMKYMNKQKCVERDEVRNVFRELQIMQG 77 Query: 1617 LDHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALE 1796 L+HPFL L+ F + +V++ GGDL Q+ F E + + Y+ E+ LALE Sbjct: 78 LEHPFLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQNV--HFTEGTVKLYICELALALE 135 Query: 1797 YLHMLGVIYRDLKPENILVRDDGHIMLSDFD 1889 YL +I+RD+KP+NIL+ + GH+ ++DF+ Sbjct: 136 YLQRYHIIHRDIKPDNILLDEHGHVHITDFN 166 Score = 60.1 bits (144), Expect = 5e-08 Identities = 37/118 (31%), Positives = 59/118 (50%), Gaps = 8/118 (6%) Frame = +3 Query: 2130 RSNSFVGTHEYLAPEIIK-----GDGHGSAVDWWTFGVFLYELLYGRTPFR---GPGNDE 2285 +++S GT Y+APE+ + G G+ VDWW+ GV YELL G P+ DE Sbjct: 176 KASSMAGTKPYMAPEVFQVYVDGGPGYSYPVDWWSLGVTAYELLRGWRPYEIHSATPIDE 235 Query: 2286 TLANVVSQNLRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPFFEGLNW 2459 L + + + + L++ LL K+PE+RL +LR +I+ + +NW Sbjct: 236 ILNMFKVERVHY--SSTWCEGMVSLLKKLLTKDPESRLSSLR---DIQSMTYLADMNW 288
>P09215:KPCD_RAT Protein kinase C delta type - Rattus norvegicus (Rat)| Length = 673 Score = 98.6 bits (244), Expect = 1e-19 Identities = 48/123 (39%), Positives = 75/123 (60%), Gaps = 2/123 (1%) Frame = +3 Query: 2124 EARSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVV 2303 E R+++F GT +Y+APEI++G + +VDWW+FGV LYE+L G++PF G DE ++ Sbjct: 500 ENRASTFCGTPDYIAPEILQGLKYSFSVDWWSFGVLLYEMLIGQSPFHGDDEDELFESIR 559 Query: 2304 SQNLRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPFFEGLNWALI--RSV 2477 +P ++ +KD++ L ++P RLG I+ HPFF+ +NW L+ R V Sbjct: 560 VDTPHYP--RWITKESKDIMEKLFERDPAKRLGV---TGNIRLHPFFKTINWNLLEKRKV 614 Query: 2478 APP 2486 PP Sbjct: 615 EPP 617 Score = 93.2 bits (230), Expect = 5e-18 Identities = 56/149 (37%), Positives = 84/149 (56%), Gaps = 1/149 (0%) Frame = +3 Query: 1443 LDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEML- 1619 L+NF K LG G G V LAEL + FA+K + + ++ + E+ +L + Sbjct: 344 LENFTFQKVLGKGSFGKVLLAELKGKERYFAIKYLKKDVVLIDDDVECTMVEKRVLALAW 403 Query: 1620 DHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALEY 1799 ++PFL L F T + VME+ GGDL + + GR F A FY AE++ L++ Sbjct: 404 ENPFLTHLICTFQTKDHLFFVMEFLNGGDL-MFHIQDKGR-FELYRATFYAAEIICGLQF 461 Query: 1800 LHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 LH G+IYRDLK +N+++ DGHI ++DF Sbjct: 462 LHGKGIIYRDLKLDNVMLDKDGHIKIADF 490
>P13677:KPC2_DROME Protein kinase C, eye isozyme - Drosophila melanogaster (Fruit fly)| Length = 700 Score = 98.6 bits (244), Expect = 1e-19 Identities = 61/147 (41%), Positives = 87/147 (59%), Gaps = 1/147 (0%) Frame = +3 Query: 1449 NFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEMLDHP 1628 +F +K +G G G V LAE +D L+A+KV+ + +I M E++IL + P Sbjct: 370 DFNFVKVIGKGSFGKVLLAERRGTDELYAVKVLRKDVIIQTDDMELPMNEKKILALSGRP 429 Query: 1629 -FLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALEYLH 1805 FL ++++ F T + VMEYC GGDL + +Q GR F E A FY EV +AL +LH Sbjct: 430 PFLVSMHSCFQTMDRLFFVMEYCKGGDL-MYHMQQYGR-FKESVAIFYAVEVAIALFFLH 487 Query: 1806 MLGVIYRDLKPENILVRDDGHIMLSDF 1886 +IYRDLK +NIL+ +GH+ L DF Sbjct: 488 ERDIIYRDLKLDNILLDGEGHVKLVDF 514 Score = 90.9 bits (224), Expect = 3e-17 Identities = 45/110 (40%), Positives = 61/110 (55%), Gaps = 1/110 (0%) Frame = +3 Query: 2133 SNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQN 2312 + +F GT Y+APEI+ D + A DWW+FGV L+E + G+ PF G N+ + Sbjct: 527 TRTFCGTPNYMAPEIVSYDPYSIAADWWSFGVLLFEFMAGQAPFEGDDETTVFRNIKDKK 586 Query: 2313 LRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLRGA-AEIKQHPFFEGLNW 2459 FP + S A D+I L K+P NRLG R A EI HPFF ++W Sbjct: 587 AVFPKH--FSVEAMDIITSFLTKKPNNRLGAGRYARQEITTHPFFRNVDW 634
>P97711:GRK6_RAT G protein-coupled receptor kinase 6 - Rattus norvegicus (Rat)| Length = 576 Score = 98.6 bits (244), Expect = 1e-19 Identities = 59/156 (37%), Positives = 88/156 (56%), Gaps = 2/156 (1%) Frame = +3 Query: 1422 LQQGPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAER 1601 L++ P+ + FR + LG G G V ++ + ++A K ++ + + RK A E+ Sbjct: 176 LERQPVTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEK 235 Query: 1602 EILEMLDHPFLPTLYAHFTTDNLSCLVMEYCPGGDL--HVLRQRQPGRSFPEPSARFYVA 1775 +ILE ++ F+ +L + T + CLV+ GGDL H+ Q G FPE A FY A Sbjct: 236 QILEKVNSRFVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGQAG--FPEARAVFYAA 293 Query: 1776 EVLLALEYLHMLGVIYRDLKPENILVRDDGHIMLSD 1883 E+ LE LH ++YRDLKPENIL+ D GHI +SD Sbjct: 294 EICCGLEDLHRERIVYRDLKPENILLDDHGHIRISD 329 Score = 66.2 bits (160), Expect = 7e-10 Identities = 40/112 (35%), Positives = 60/112 (53%), Gaps = 7/112 (6%) Frame = +3 Query: 2145 VGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGND------ETLANVVS 2306 VGT Y+APE++K + + + DWW G LYE++ G++PF+ E L V+ Sbjct: 346 VGTVGYMAPEVVKNERYTFSPDWWALGCLLYEMIAGQSPFQQRKKKIKREEVERLVKEVA 405 Query: 2307 QNLRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLRGAA-EIKQHPFFEGLNW 2459 + + D S A+ L L K+P RLG G A E+K+HP F+ LN+ Sbjct: 406 E--EYTDR--FSPQARSLCSQLPNKDPAERLGCRGGGAREVKEHPLFKKLNF 453
>O70293:GRK6_MOUSE G protein-coupled receptor kinase 6 - Mus musculus (Mouse)| Length = 576 Score = 98.6 bits (244), Expect = 1e-19 Identities = 59/156 (37%), Positives = 88/156 (56%), Gaps = 2/156 (1%) Frame = +3 Query: 1422 LQQGPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAER 1601 L++ P+ + FR + LG G G V ++ + ++A K ++ + + RK A E+ Sbjct: 176 LERQPVTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEK 235 Query: 1602 EILEMLDHPFLPTLYAHFTTDNLSCLVMEYCPGGDL--HVLRQRQPGRSFPEPSARFYVA 1775 +ILE ++ F+ +L + T + CLV+ GGDL H+ Q G FPE A FY A Sbjct: 236 QILEKVNSRFVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGQAG--FPEARAVFYAA 293 Query: 1776 EVLLALEYLHMLGVIYRDLKPENILVRDDGHIMLSD 1883 E+ LE LH ++YRDLKPENIL+ D GHI +SD Sbjct: 294 EICCGLEDLHRERIVYRDLKPENILLDDHGHIRISD 329 Score = 70.1 bits (170), Expect = 5e-11 Identities = 41/112 (36%), Positives = 62/112 (55%), Gaps = 7/112 (6%) Frame = +3 Query: 2145 VGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGND------ETLANVVS 2306 VGT Y+APE+++ + + + DWW G LYE++ G++PF+ E L V+ Sbjct: 346 VGTVGYMAPEVVRNERYTFSPDWWALGCLLYEMIAGQSPFQQRKKKIKREEVERLVKEVA 405 Query: 2307 QNLRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLRGAA-EIKQHPFFEGLNW 2459 + + D SS A+ L LL K+P RLG G A E+K+HP F+ LN+ Sbjct: 406 E--EYTDR--FSSQARSLCSQLLSKDPAERLGCRGGGAREVKEHPLFKKLNF 453
>P43250:GRK6_HUMAN G protein-coupled receptor kinase 6 - Homo sapiens (Human)| Length = 576 Score = 98.6 bits (244), Expect = 1e-19 Identities = 59/156 (37%), Positives = 88/156 (56%), Gaps = 2/156 (1%) Frame = +3 Query: 1422 LQQGPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAER 1601 L++ P+ + FR + LG G G V ++ + ++A K ++ + + RK A E+ Sbjct: 176 LERQPVTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEK 235 Query: 1602 EILEMLDHPFLPTLYAHFTTDNLSCLVMEYCPGGDL--HVLRQRQPGRSFPEPSARFYVA 1775 +ILE ++ F+ +L + T + CLV+ GGDL H+ Q G FPE A FY A Sbjct: 236 QILEKVNSRFVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGQAG--FPEARAVFYAA 293 Query: 1776 EVLLALEYLHMLGVIYRDLKPENILVRDDGHIMLSD 1883 E+ LE LH ++YRDLKPENIL+ D GHI +SD Sbjct: 294 EICCGLEDLHRERIVYRDLKPENILLDDHGHIRISD 329 Score = 70.5 bits (171), Expect = 4e-11 Identities = 39/108 (36%), Positives = 59/108 (54%), Gaps = 3/108 (2%) Frame = +3 Query: 2145 VGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQNLRFP 2324 VGT Y+APE++K + + + DWW G LYE++ G++PF+ V P Sbjct: 346 VGTVGYMAPEVVKNERYTFSPDWWALGCLLYEMIAGQSPFQQRKKKIKREEVERLVKEVP 405 Query: 2325 D--NPVVSSNAKDLIRGLLVKEPENRLGTLRGAA-EIKQHPFFEGLNW 2459 + + S A+ L LL K+P RLG G+A E+K+HP F+ LN+ Sbjct: 406 EEYSERFSPQARSLCSQLLCKDPAERLGCRGGSAREVKEHPLFKKLNF 453
>Q09537:GRK1_CAEEL G protein-coupled receptor kinase 1 - Caenorhabditis elegans| Length = 642 Score = 98.6 bits (244), Expect = 1e-19 Identities = 57/155 (36%), Positives = 89/155 (57%), Gaps = 1/155 (0%) Frame = +3 Query: 1422 LQQGPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAER 1601 L++ P+ FRL + LG G G V ++ S ++ALK ++ + + R + E+ Sbjct: 193 LEKRPVDKHTFRLYRVLGKGGFGEVCACQVRASGKMYALKKLEKKRVKKRHAETLSLNEK 252 Query: 1602 EILEMLDHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHV-LRQRQPGRSFPEPSARFYVAE 1778 +IL+ ++ PF+ +L + T + CLV+ GGDL L PG F E +FY AE Sbjct: 253 QILQRINSPFVVSLAYAYETKDALCLVLTLMNGGDLKFHLYNLMPG-GFDEKRVQFYAAE 311 Query: 1779 VLLALEYLHMLGVIYRDLKPENILVRDDGHIMLSD 1883 + L L++LH ++YRDLKPENIL+ D GH+ +SD Sbjct: 312 ITLGLQHLHSERILYRDLKPENILLDDFGHVRISD 346 Score = 75.1 bits (183), Expect = 1e-12 Identities = 49/132 (37%), Positives = 66/132 (50%), Gaps = 9/132 (6%) Frame = +3 Query: 2115 EPTEARSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLA 2294 EP + R VGT Y+APEI+K + + VDWW G +YE++ G+ PFR ++ Sbjct: 357 EPIKGR----VGTVGYMAPEIVKNERYSYGVDWWGVGCLIYEMIEGKAPFR-QRKEKVKR 411 Query: 2295 NVVSQNLRFPD---NPVVSSNAKDLIRGLLVKEPENRLGTLR------GAAEIKQHPFFE 2447 V + +R + S A+ L RGLL KEP RLG R GA EI+ HPFF Sbjct: 412 EEVERRVREDQEKYSEKFSEAARTLCRGLLHKEPGFRLGCRRVGRPEDGAEEIRAHPFFN 471 Query: 2448 GLNWALIRSVAP 2483 + R P Sbjct: 472 TADTVTGREPVP 483
>Q8QZV4:ST32C_MOUSE Serine/threonine-protein kinase 32C - Mus musculus (Mouse)| Length = 488 Score = 98.2 bits (243), Expect = 2e-19 Identities = 51/151 (33%), Positives = 89/151 (58%) Frame = +3 Query: 1437 LGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEM 1616 + D+F++L+ +G G G V + + D++ ++A+K M+ + I R ++ E EIL+ Sbjct: 89 VNFDHFQILRAIGKGSFGKVCIVQKRDTEKMYAMKYMNKQQCIERDEVRNVFRELEILQE 148 Query: 1617 LDHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALE 1796 ++H FL L+ F + +V++ GGDL Q+ F E + R Y+ E+ LAL+ Sbjct: 149 IEHVFLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQNV--QFSEDTVRLYICEMALALD 206 Query: 1797 YLHMLGVIYRDLKPENILVRDDGHIMLSDFD 1889 YL +I+RD+KP+NIL+ + GH L+DF+ Sbjct: 207 YLRSQHIIHRDVKPDNILLDEQGHAHLTDFN 237 Score = 53.1 bits (126), Expect = 6e-06 Identities = 35/101 (34%), Positives = 48/101 (47%), Gaps = 7/101 (6%) Frame = +3 Query: 2130 RSNSFVGTHEYLAPEIIK-----GDGHGSAVDWWTFGVFLYELLYGRTPF--RGPGNDET 2288 R+ + GT Y+APEI G G+ VDWW+ GV YELL G P+ E+ Sbjct: 247 RATALAGTKPYMAPEIFHSFVNGGTGYSFEVDWWSVGVMAYELLRGWRPYDIHSSNAVES 306 Query: 2289 LANVVSQNLRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLR 2411 L + S + P S L+R LL PE+R +L+ Sbjct: 307 LVQLFS-TVSVQYVPTWSKEMVALLRKLLTVNPEHRFSSLQ 346
>Q5PU49:KPCD_CANFA Protein kinase C delta type - Canis familiaris (Dog)| Length = 674 Score = 98.2 bits (243), Expect = 2e-19 Identities = 48/123 (39%), Positives = 76/123 (61%), Gaps = 2/123 (1%) Frame = +3 Query: 2124 EARSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVV 2303 E ++++F GT +Y+APEI++G + +VDWW+FGV LYE+L G++PF G DE ++ Sbjct: 500 EKQASTFCGTPDYIAPEILQGLKYSFSVDWWSFGVLLYEMLIGQSPFHGDDEDELFESIR 559 Query: 2304 SQNLRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPFFEGLNWALI--RSV 2477 +P ++ +KD++ LL ++ RLG IK HPFF+ +NW L+ R+V Sbjct: 560 VDTPHYP--RWITKESKDILEKLLERDTTKRLGV---TGNIKIHPFFKTINWTLLEKRAV 614 Query: 2478 APP 2486 PP Sbjct: 615 EPP 617 Score = 92.0 bits (227), Expect = 1e-17 Identities = 55/149 (36%), Positives = 83/149 (55%), Gaps = 1/149 (0%) Frame = +3 Query: 1443 LDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEML- 1619 +DNF K LG G G V L EL FA+K + + ++ + E+ +L + Sbjct: 344 IDNFIFHKVLGKGSFGKVLLVELKGKKEFFAIKALKKDVVLIDDDVECTMVEKRVLALAW 403 Query: 1620 DHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALEY 1799 ++PFL L+ F T + VME+ GGDL + + GR F A FY AE++ L++ Sbjct: 404 ENPFLTHLFCTFQTKDHLFFVMEFLNGGDL-MYHIQDKGR-FELYRATFYAAEIVCGLQF 461 Query: 1800 LHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 LH G+IYRDLK +N+++ DGHI ++DF Sbjct: 462 LHNKGIIYRDLKLDNVMLDQDGHIKIADF 490
>P68403:KPCB_RAT Protein kinase C beta type - Rattus norvegicus (Rat)| Length = 671 Score = 98.2 bits (243), Expect = 2e-19 Identities = 47/121 (38%), Positives = 72/121 (59%), Gaps = 3/121 (2%) Frame = +3 Query: 2133 SNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQN 2312 + +F GT +Y+APEII +G +VDWW FGV LYE+L G+ PF G DE +++ N Sbjct: 498 TKTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIMEHN 557 Query: 2313 LRFPDNPVVSSNAKDLIRGLLVKEPENRLGT-LRGAAEIKQHPFFEGLNWALI--RSVAP 2483 + +P + +S A + +GL+ K P RLG G +IK+H FF ++W + + + P Sbjct: 558 VAYPKS--MSKEAVAICKGLMTKHPGKRLGCGPEGERDIKEHAFFRYIDWEKLERKEIQP 615 Query: 2484 P 2486 P Sbjct: 616 P 616 Score = 94.0 bits (232), Expect = 3e-18 Identities = 57/149 (38%), Positives = 86/149 (57%), Gaps = 1/149 (0%) Frame = +3 Query: 1443 LDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEMLD 1622 L +F L LG G G V L+E +D L+A+K++ + +I + E+ +L + Sbjct: 339 LTDFNFLMVLGKGSFGKVMLSERKGTDELYAVKILKKDVVIQDDDVECTMVEKRVLALPG 398 Query: 1623 HP-FLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALEY 1799 P FL L++ F T + VMEY GGDL + +Q GR F EP A FY AE+ + L + Sbjct: 399 KPPFLTQLHSCFQTMDRLYFVMEYVNGGDL-MYHIQQVGR-FKEPHAVFYAAEIAIGLFF 456 Query: 1800 LHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 L G+IYRDLK +N+++ +GHI ++DF Sbjct: 457 LQSKGIIYRDLKLDNVMLDSEGHIKIADF 485
>P68404:KPCB_MOUSE Protein kinase C beta type - Mus musculus (Mouse)| Length = 673 Score = 98.2 bits (243), Expect = 2e-19 Identities = 47/121 (38%), Positives = 72/121 (59%), Gaps = 3/121 (2%) Frame = +3 Query: 2133 SNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQN 2312 + +F GT +Y+APEII +G +VDWW FGV LYE+L G+ PF G DE +++ N Sbjct: 498 TKTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIMEHN 557 Query: 2313 LRFPDNPVVSSNAKDLIRGLLVKEPENRLGT-LRGAAEIKQHPFFEGLNWALI--RSVAP 2483 + +P + +S A + +GL+ K P RLG G +IK+H FF ++W + + + P Sbjct: 558 VAYPKS--MSKEAVAICKGLMTKHPGKRLGCGPEGERDIKEHAFFRYIDWEKLERKEIQP 615 Query: 2484 P 2486 P Sbjct: 616 P 616 Score = 94.0 bits (232), Expect = 3e-18 Identities = 57/149 (38%), Positives = 86/149 (57%), Gaps = 1/149 (0%) Frame = +3 Query: 1443 LDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEMLD 1622 L +F L LG G G V L+E +D L+A+K++ + +I + E+ +L + Sbjct: 339 LTDFNFLMVLGKGSFGKVMLSERKGTDELYAVKILKKDVVIQDDDVECTMVEKRVLALPG 398 Query: 1623 HP-FLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALEY 1799 P FL L++ F T + VMEY GGDL + +Q GR F EP A FY AE+ + L + Sbjct: 399 KPPFLTQLHSCFQTMDRLYFVMEYVNGGDL-MYHIQQVGR-FKEPHAVFYAAEIAIGLFF 456 Query: 1800 LHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 L G+IYRDLK +N+++ +GHI ++DF Sbjct: 457 LQSKGIIYRDLKLDNVMLDSEGHIKIADF 485
>P05771:KPCB_HUMAN Protein kinase C beta type - Homo sapiens (Human)| Length = 671 Score = 98.2 bits (243), Expect = 2e-19 Identities = 47/121 (38%), Positives = 72/121 (59%), Gaps = 3/121 (2%) Frame = +3 Query: 2133 SNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQN 2312 + +F GT +Y+APEII +G +VDWW FGV LYE+L G+ PF G DE +++ N Sbjct: 498 TKTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIMEHN 557 Query: 2313 LRFPDNPVVSSNAKDLIRGLLVKEPENRLGT-LRGAAEIKQHPFFEGLNWALI--RSVAP 2483 + +P + +S A + +GL+ K P RLG G +IK+H FF ++W + + + P Sbjct: 558 VAYPKS--MSKEAVAICKGLMTKHPGKRLGCGPEGERDIKEHAFFRYIDWEKLERKEIQP 615 Query: 2484 P 2486 P Sbjct: 616 P 616 Score = 94.0 bits (232), Expect = 3e-18 Identities = 57/149 (38%), Positives = 86/149 (57%), Gaps = 1/149 (0%) Frame = +3 Query: 1443 LDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEMLD 1622 L +F L LG G G V L+E +D L+A+K++ + +I + E+ +L + Sbjct: 339 LTDFNFLMVLGKGSFGKVMLSERKGTDELYAVKILKKDVVIQDDDVECTMVEKRVLALPG 398 Query: 1623 HP-FLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALEY 1799 P FL L++ F T + VMEY GGDL + +Q GR F EP A FY AE+ + L + Sbjct: 399 KPPFLTQLHSCFQTMDRLYFVMEYVNGGDL-MYHIQQVGR-FKEPHAVFYAAEIAIGLFF 456 Query: 1800 LHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 L G+IYRDLK +N+++ +GHI ++DF Sbjct: 457 LQSKGIIYRDLKLDNVMLDSEGHIKIADF 485
>P05126:KPCB_BOVIN Protein kinase C beta type - Bos taurus (Bovine)| Length = 673 Score = 98.2 bits (243), Expect = 2e-19 Identities = 47/121 (38%), Positives = 72/121 (59%), Gaps = 3/121 (2%) Frame = +3 Query: 2133 SNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQN 2312 + +F GT +Y+APEII +G +VDWW FGV LYE+L G+ PF G DE +++ N Sbjct: 498 TKTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIMEHN 557 Query: 2313 LRFPDNPVVSSNAKDLIRGLLVKEPENRLGT-LRGAAEIKQHPFFEGLNWALI--RSVAP 2483 + +P + +S A + +GL+ K P RLG G +IK+H FF ++W + + + P Sbjct: 558 VAYPKS--MSKEAVAICKGLITKHPGKRLGCGPEGERDIKEHAFFRYIDWEKLERKEIQP 615 Query: 2484 P 2486 P Sbjct: 616 P 616 Score = 94.0 bits (232), Expect = 3e-18 Identities = 57/149 (38%), Positives = 86/149 (57%), Gaps = 1/149 (0%) Frame = +3 Query: 1443 LDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEMLD 1622 L +F L LG G G V L+E +D L+A+K++ + +I + E+ +L + Sbjct: 339 LTDFNFLMVLGKGSFGKVMLSERKGTDELYAVKILKKDVVIQDDDVECTMVEKRVLALPG 398 Query: 1623 HP-FLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALEY 1799 P FL L++ F T + VMEY GGDL + +Q GR F EP A FY AE+ + L + Sbjct: 399 KPPFLTQLHSCFQTMDRLYFVMEYVNGGDL-MYHIQQVGR-FKEPHAVFYAAEIAIGLFF 456 Query: 1800 LHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 L G+IYRDLK +N+++ +GHI ++DF Sbjct: 457 LQSKGIIYRDLKLDNVMLDSEGHIKIADF 485
>O14578:CTRO_HUMAN Citron Rho-interacting kinase - Homo sapiens (Human)| Length = 2027 Score = 98.2 bits (243), Expect = 2e-19 Identities = 57/155 (36%), Positives = 88/155 (56%) Frame = +3 Query: 1422 LQQGPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAER 1601 LQ+ +F + +GCG V + + ++A+KVM + L++++++ + ER Sbjct: 87 LQELQPSAKDFEVRSLVGCGHFAEVQVVREKATGDIYAMKVMKKKALLAQEQVSFFEEER 146 Query: 1602 EILEMLDHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEV 1781 IL P++P L F N LVMEY PGGDL L R + E +FY+AE+ Sbjct: 147 NILSRSTSPWIPQLQYAFQDKNHLYLVMEYQPGGDLLSLLNRYEDQ-LDENLIQFYLAEL 205 Query: 1782 LLALEYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 +LA+ +H++G ++RD+KPENILV GHI L DF Sbjct: 206 ILAVHSVHLMGYVHRDIKPENILVDRTGHIKLVDF 240 Score = 84.0 bits (206), Expect = 3e-15 Identities = 48/122 (39%), Positives = 72/122 (59%), Gaps = 8/122 (6%) Frame = +3 Query: 2145 VGTHEYLAPEII---KGDGHGSA---VDWWTFGVFLYELLYGRTPFRGPGNDETLANVVS 2306 +GT +Y+APE++ GDG G+ DWW+ GV YE++YGR+PF + T N+++ Sbjct: 258 IGTPDYMAPEVLTVMNGDGKGTYGLDCDWWSVGVIAYEMIYGRSPFAEGTSARTFNNIMN 317 Query: 2307 --QNLRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPFFEGLNWALIRSVA 2480 + L+FPD+P VSS+ DLI+ LL + E G + HPFF ++W IR+ Sbjct: 318 FQRFLKFPDDPKVSSDFLDLIQSLLCGQKERL--KFEG---LCCHPFFSKIDWNNIRNSP 372 Query: 2481 PP 2486 PP Sbjct: 373 PP 374
>P11792:SCH9_YEAST Serine/threonine-protein kinase SCH9 - Saccharomyces cerevisiae| (Baker's yeast) Length = 824 Score = 97.8 bits (242), Expect = 2e-19 Identities = 59/152 (38%), Positives = 89/152 (58%), Gaps = 3/152 (1%) Frame = +3 Query: 1440 GLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEML 1619 G +F +L+ LG G G VY + D+ ++A+KV+ + ++ + ++ ER IL Sbjct: 408 GPQDFEVLRLLGKGTFGQVYQVKKKDTQRIYAMKVLSKKVIVKKNEIAHTIGERNILVTT 467 Query: 1620 ---DHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLA 1790 PF+ L F T LV +Y GG+L Q++ GR F E A+FY+AE++LA Sbjct: 468 ASKSSPFIVGLKFSFQTPTDLYLVTDYMSGGELFWHLQKE-GR-FSEDRAKFYIAELVLA 525 Query: 1791 LEYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 LE+LH ++YRDLKPENIL+ +G+I L DF Sbjct: 526 LEHLHDNDIVYRDLKPENILLDANGNIALCDF 557 Score = 91.3 bits (225), Expect = 2e-17 Identities = 44/125 (35%), Positives = 75/125 (60%), Gaps = 2/125 (1%) Frame = +3 Query: 2130 RSNSFVGTHEYLAPEIIKGD-GHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVS 2306 R+N+F GT EYLAPE++ + G+ VD+W+ GV ++E+ G +PF N + + Sbjct: 567 RTNTFCGTTEYLAPELLLDETGYTKMVDFWSLGVLIFEMCCGWSPFFAENNQKMYQKIAF 626 Query: 2307 QNLRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPFFEGLNW-ALIRSVAP 2483 ++FP + V+S + ++GLL + P++RLG + E++ HPFF ++W AL + P Sbjct: 627 GKVKFPRD-VLSQEGRSFVKGLLNRNPKHRLGAIDDGRELRAHPFFADIDWEALKQKKIP 685 Query: 2484 PETRP 2498 P +P Sbjct: 686 PPFKP 690
>Q80UW5:MRCKG_MOUSE Serine/threonine-protein kinase MRCK gamma - Mus musculus (Mouse)| Length = 1551 Score = 97.8 bits (242), Expect = 2e-19 Identities = 59/160 (36%), Positives = 94/160 (58%) Frame = +3 Query: 1407 IRQLALQQGPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLR 1586 +++L LQ+ D+F +LK +G G G V + S +FA+K++ ++ R + Sbjct: 61 VKELRLQR-----DDFEILKVIGRGAFGEVAVVRQRGSGQIFAMKMLHKWEMLKRAETAC 115 Query: 1587 AQAEREILEMLDHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARF 1766 + ER++L D ++ L+ F + LVM+Y GGDL L R R PE A+F Sbjct: 116 FREERDVLVKGDSRWVTALHYAFQDEEYLYLVMDYYAGGDLLTLLSRFEDRLPPE-LAQF 174 Query: 1767 YVAEVLLALEYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 Y+AE++LA+ LH LG ++RD+KP+NIL+ +GHI L+DF Sbjct: 175 YLAEMVLAIHSLHQLGYVHRDVKPDNILLDMNGHIRLADF 214 Score = 88.6 bits (218), Expect = 1e-16 Identities = 58/132 (43%), Positives = 81/132 (61%), Gaps = 11/132 (8%) Frame = +3 Query: 2133 SNSFVGTHEYLAPEIIK----GDGH-GSAVDWWTFGVFLYELLYGRTPFRGPGNDETLAN 2297 S+ VGT +Y++PEI++ G GH G DWW+ GV YELL+G TPF ET Sbjct: 228 SSVAVGTPDYISPEILQAMEEGKGHYGPQCDWWSLGVCAYELLFGETPFYAESLVETYGK 287 Query: 2298 VVS--QNLRFP-DNPVVSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPFFEGLNW-AL 2465 +++ +L+FP D V ++A+DLIR LL ++ E RLG G + ++HPFFEG++W L Sbjct: 288 IMNHEDHLQFPADVTDVPASAQDLIRQLLCRQ-EERLGR-GGLDDFRKHPFFEGVDWERL 345 Query: 2466 IRSVAP--PETR 2495 S AP PE R Sbjct: 346 ATSTAPYIPELR 357
>Q12236:KOK0_YEAST Probable serine/threonine-protein kinase YOL100W - Saccharomyces| cerevisiae (Baker's yeast) Length = 1081 Score = 97.8 bits (242), Expect = 2e-19 Identities = 61/186 (32%), Positives = 101/186 (54%), Gaps = 15/186 (8%) Frame = +3 Query: 1374 PHMVKDLCWITIRQLALQQGPL--------------GLDNFRLLKRLGCGDIGTVYLAEL 1511 PHM K+ + I + Q P+ G+ +F+ +G G TV LA Sbjct: 139 PHMEKNRNKVKIEHDSSSQKPIAKESSKAQKNIIKKGIKDFKFGSVIGDGAYSTVMLATS 198 Query: 1512 VDSDCLFALKVMDIEYLISRKKMLRAQAEREILEMLDH-PFLPTLYAHFTTDNLSCLVME 1688 +D+ +A KV++ EYLI +KK+ E+ L+ L++ P + L++ F ++ ++E Sbjct: 199 IDTKKRYAAKVLNKEYLIRQKKVKYVSIEKTALQKLNNSPSVVRLFSTFQDESSLYFLLE 258 Query: 1689 YCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALEYLHMLGVIYRDLKPENILVRDDGH 1868 Y P GD L ++ S E AR+Y A+++ A++YLH G+I+RD+KPENIL+ + Sbjct: 259 YAPNGDFLSLMKKYG--SLDETCARYYAAQIIDAIDYLHSNGIIHRDIKPENILLDGEMK 316 Query: 1869 IMLSDF 1886 I L+DF Sbjct: 317 IKLTDF 322 Score = 72.8 bits (177), Expect = 7e-12 Identities = 43/126 (34%), Positives = 68/126 (53%), Gaps = 3/126 (2%) Frame = +3 Query: 2130 RSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQ 2309 RS SFVGT EY++PE++ D W FG L++++ G+ PF+ T V+ Sbjct: 345 RSKSFVGTAEYVSPELLNDSFTDYRCDIWAFGCILFQMIAGKPPFKATNEYLTFQKVMKV 404 Query: 2310 NLRF-PDNPVVSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPFFEGLNW--ALIRSVA 2480 F P P++ +DL++ +LVK + RL ++IK+H FF+ LN+ + S Sbjct: 405 QYAFTPGFPLI---IRDLVKKILVKNLDRRL----TISQIKEHHFFKDLNFKDGSVWSKT 457 Query: 2481 PPETRP 2498 PPE +P Sbjct: 458 PPEIKP 463
>Q63651:RK_RAT Rhodopsin kinase precursor - Rattus norvegicus (Rat)| Length = 564 Score = 97.4 bits (241), Expect = 3e-19 Identities = 56/156 (35%), Positives = 86/156 (55%), Gaps = 2/156 (1%) Frame = +3 Query: 1422 LQQGPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAER 1601 L+ P+G D F + LG G G V ++ + ++A K ++ + L RK A E+ Sbjct: 180 LEAQPIGEDWFLDFRVLGKGGFGEVSACQMKATGKMYACKKLNKKRLKKRKGYQGAIVEK 239 Query: 1602 EILEMLDHPFLPTLYAHFTTDNLSCLVMEYCPGGDL--HVLRQRQPGRSFPEPSARFYVA 1775 IL + F+ +L F T CLVM GGD+ H+ + FPEP A +Y A Sbjct: 240 RILAKVHSRFIVSLAYAFETKTDLCLVMTIMNGGDVRYHIYNVDEENPGFPEPRAIYYTA 299 Query: 1776 EVLLALEYLHMLGVIYRDLKPENILVRDDGHIMLSD 1883 +++ LE+LH ++YRDLKPEN+L+ +DG+I +SD Sbjct: 300 QIISGLEHLHQRRIVYRDLKPENVLLDNDGNIRISD 335 Score = 72.8 bits (177), Expect = 7e-12 Identities = 42/136 (30%), Positives = 77/136 (56%), Gaps = 9/136 (6%) Frame = +3 Query: 2106 LVVEPTEARSNS--FVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPG- 2276 L VE E ++ + + GT ++APE+++G+ + +VD++ GV LYE++ R PFR G Sbjct: 338 LAVELKEGQNKTKGYAGTPGFMAPELLRGEEYDFSVDYFALGVTLYEMIAARGPFRARGE 397 Query: 2277 ---NDETLANVVSQNLRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLRGAAE-IKQHPFF 2444 N E ++S+ +++P+ S +KD LL K+PE RLG G + ++ + F Sbjct: 398 KVENKELKQRIISEPVKYPEK--FSQASKDFCEQLLEKDPEKRLGFRDGTCDALRANVLF 455 Query: 2445 EGLNWALIRS--VAPP 2486 + ++W + + + PP Sbjct: 456 KDISWRQLEAGMLIPP 471
>Q8K045:PKN3_MOUSE Serine/threonine-protein kinase N3 - Mus musculus (Mouse)| Length = 878 Score = 97.4 bits (241), Expect = 3e-19 Identities = 61/175 (34%), Positives = 91/175 (52%), Gaps = 3/175 (1%) Frame = +3 Query: 1371 RPHMVKDLCWITIRQLALQQGPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMD 1550 RPHM + + P L +FR L LG G G V L + + +A+K + Sbjct: 521 RPHMDPRPAVVPALAALSTRKPPRLQDFRCLAVLGRGHFGKVLLVQYKGTGKYYAIKALK 580 Query: 1551 IEYLISRKKMLRAQAEREILEMLD---HPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLR 1721 + ++ R ++ E+ ILE + HPFL +L A T + +C V E+ PGGDL Sbjct: 581 KQEVLGRDEIDSLYCEKRILETVGRTGHPFLLSLLACLQTSSHACFVTEFLPGGDLMAQI 640 Query: 1722 QRQPGRSFPEPSARFYVAEVLLALEYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 FPEP A FY+A V+L L++LH +IYRDLK +N+L+ G + ++DF Sbjct: 641 HEDV---FPEPQACFYLACVVLGLQFLHEKRIIYRDLKLDNLLLDAQGFLKIADF 692 Score = 95.9 bits (237), Expect = 8e-19 Identities = 54/122 (44%), Positives = 71/122 (58%), Gaps = 3/122 (2%) Frame = +3 Query: 2130 RSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQ 2309 R+++F GT E+LAPE++ + + AVDWW GV LYE+L G PF G +E +VS Sbjct: 704 RTSTFCGTPEFLAPEVLTQEAYTRAVDWWGLGVLLYEMLVGECPFPGDTEEEVFECIVSA 763 Query: 2310 NLRFPDNPVVSSNAKDLIRGLLVKEPENRLGT-LRGAAEIKQHPFFEGLNW--ALIRSVA 2480 ++ P +S +LI+ LL K PE RLG R A EIK PFF NW L R+V Sbjct: 764 DVPCPH--FLSVQGLELIQKLLQKSPEKRLGAGERDAEEIKVQPFFRTTNWQALLARTVQ 821 Query: 2481 PP 2486 PP Sbjct: 822 PP 823
>P05772:KPCB_RABIT Protein kinase C beta type - Oryctolagus cuniculus (Rabbit)| Length = 671 Score = 97.4 bits (241), Expect = 3e-19 Identities = 47/121 (38%), Positives = 71/121 (58%), Gaps = 3/121 (2%) Frame = +3 Query: 2133 SNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQN 2312 + +F GT +Y+APEII +G +VDWW FGV LYE+L G+ PF G DE +++ N Sbjct: 498 TKTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIMEHN 557 Query: 2313 LRFPDNPVVSSNAKDLIRGLLVKEPENRLGT-LRGAAEIKQHPFFEGLNWALI--RSVAP 2483 + +P + +S A + +GL+ K P RLG G +IK H FF ++W + + + P Sbjct: 558 VAYPKS--MSKEAVAICKGLMTKHPGKRLGCGPEGERDIKDHAFFRYIDWEKLERKEIQP 615 Query: 2484 P 2486 P Sbjct: 616 P 616 Score = 94.0 bits (232), Expect = 3e-18 Identities = 57/149 (38%), Positives = 86/149 (57%), Gaps = 1/149 (0%) Frame = +3 Query: 1443 LDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEMLD 1622 L +F L LG G G V L+E +D L+A+K++ + +I + E+ +L + Sbjct: 339 LTDFNFLMVLGKGSFGKVMLSERKGTDELYAVKILKKDVVIQDDDVECTMVEKRVLALPG 398 Query: 1623 HP-FLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALEY 1799 P FL L++ F T + VMEY GGDL + +Q GR F EP A FY AE+ + L + Sbjct: 399 KPPFLTQLHSCFQTMDRLYFVMEYVNGGDL-MYHIQQVGR-FKEPHAVFYAAEIAIGLFF 456 Query: 1800 LHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 L G+IYRDLK +N+++ +GHI ++DF Sbjct: 457 LQSKGIIYRDLKLDNVMLDSEGHIKIADF 485
>P43249:GRK5_BOVIN G protein-coupled receptor kinase 5 - Bos taurus (Bovine)| Length = 590 Score = 97.4 bits (241), Expect = 3e-19 Identities = 59/156 (37%), Positives = 87/156 (55%), Gaps = 2/156 (1%) Frame = +3 Query: 1422 LQQGPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAER 1601 L++ P+ + FR + LG G G V ++ + ++A K ++ + + RK A E+ Sbjct: 176 LERQPVTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKRLEKKRIKKRKGESMALNEK 235 Query: 1602 EILEMLDHPFLPTLYAHFTTDNLSCLVMEYCPGGDL--HVLRQRQPGRSFPEPSARFYVA 1775 +ILE ++ F+ L + T + CLV+ GGDL H+ PG F E A FY A Sbjct: 236 QILEKVNSRFVVNLAYAYETKDALCLVLTIMNGGDLKFHIYNMGNPG--FEEERALFYAA 293 Query: 1776 EVLLALEYLHMLGVIYRDLKPENILVRDDGHIMLSD 1883 E+L LE LH ++YRDLKPENIL+ D GHI +SD Sbjct: 294 EILCGLEDLHHENIVYRDLKPENILLDDYGHIRISD 329 Score = 73.2 bits (178), Expect = 6e-12 Identities = 39/108 (36%), Positives = 61/108 (56%), Gaps = 3/108 (2%) Frame = +3 Query: 2145 VGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQNLRFP 2324 VGT Y+APE++ +G + D+W G +YE++ G++PFRG V + L Sbjct: 346 VGTVGYMAPEVLNNQRYGLSPDYWGLGCLIYEMIEGQSPFRGRKEKVKREEVDRRVLETE 405 Query: 2325 D--NPVVSSNAKDLIRGLLVKEPENRLGTL-RGAAEIKQHPFFEGLNW 2459 + + S AK + + LL K+ + RLG GAAE+K+HPFF +N+ Sbjct: 406 EVYSHKFSEEAKSICKMLLTKDAKQRLGCQEEGAAEVKRHPFFRNMNF 453
>Q62868:ROCK2_RAT Rho-associated protein kinase 2 - Rattus norvegicus (Rat)| Length = 1379 Score = 97.1 bits (240), Expect = 4e-19 Identities = 53/147 (36%), Positives = 85/147 (57%) Frame = +3 Query: 1446 DNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEMLDH 1625 +++ ++K +G G G V L S ++A+K++ +I R ER+I+ + Sbjct: 81 EDYDVVKVIGRGAFGEVQLVRHKASQKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANS 140 Query: 1626 PFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALEYLH 1805 P++ L+ F D +VMEY PGGDL L PE A+FY AEV+LAL+ +H Sbjct: 141 PWVVQLFCAFQDDRYLYMVMEYMPGGDLVNLMSNY---DVPEKWAKFYTAEVVLALDAIH 197 Query: 1806 MLGVIYRDLKPENILVRDDGHIMLSDF 1886 +G+I+RD+KP+N+L+ GH+ L+DF Sbjct: 198 SMGLIHRDVKPDNMLLDKHGHLKLADF 224 Score = 78.2 bits (191), Expect = 2e-13 Identities = 50/122 (40%), Positives = 70/122 (57%), Gaps = 8/122 (6%) Frame = +3 Query: 2145 VGTHEYLAPEIIK---GDGH-GSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVV--S 2306 VGT +Y++PE++K GDG+ G DWW+ GVFL+E+L G TPF T + ++ Sbjct: 242 VGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLFEMLVGDTPFYADSLVGTYSKIMDHK 301 Query: 2307 QNLRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPFFEG--LNWALIRSVA 2480 +L FP++ +S +AK+LI L + E RLG G EIK FF+ NW IR A Sbjct: 302 NSLCFPEDTEISKHAKNLICAFLT-DREVRLGR-NGVEEIKSASFFKNDQWNWDNIRETA 359 Query: 2481 PP 2486 P Sbjct: 360 AP 361
>P70336:ROCK2_MOUSE Rho-associated protein kinase 2 - Mus musculus (Mouse)| Length = 1388 Score = 97.1 bits (240), Expect = 4e-19 Identities = 53/147 (36%), Positives = 85/147 (57%) Frame = +3 Query: 1446 DNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEMLDH 1625 +++ ++K +G G G V L S ++A+K++ +I R ER+I+ + Sbjct: 90 EDYDVVKVIGRGAFGEVQLVRHKASQKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANS 149 Query: 1626 PFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALEYLH 1805 P++ L+ F D +VMEY PGGDL L PE A+FY AEV+LAL+ +H Sbjct: 150 PWVVQLFCAFQDDRYLYMVMEYMPGGDLVNLMSNY---DVPEKWAKFYTAEVVLALDAIH 206 Query: 1806 MLGVIYRDLKPENILVRDDGHIMLSDF 1886 +G+I+RD+KP+N+L+ GH+ L+DF Sbjct: 207 SMGLIHRDVKPDNMLLDKHGHLKLADF 233 Score = 87.0 bits (214), Expect = 4e-16 Identities = 53/122 (43%), Positives = 73/122 (59%), Gaps = 8/122 (6%) Frame = +3 Query: 2145 VGTHEYLAPEIIK---GDGH-GSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVV--S 2306 VGT +Y++PE++K GDG+ G DWW+ GVFL+E+L G TPF T + ++ Sbjct: 251 VGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLFEMLVGDTPFYADSLVGTYSKIMDHK 310 Query: 2307 QNLRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPFFEG--LNWALIRSVA 2480 +L FP++ +S +AK+LI L + E RLG G EIKQHPFF+ NW IR A Sbjct: 311 NSLCFPEDTEISKHAKNLICAFLT-DREVRLGR-NGVEEIKQHPFFKNDQWNWDNIRETA 368 Query: 2481 PP 2486 P Sbjct: 369 AP 370
>Q28021:ROCK2_BOVIN Rho-associated protein kinase 2 - Bos taurus (Bovine)| Length = 1388 Score = 97.1 bits (240), Expect = 4e-19 Identities = 53/147 (36%), Positives = 85/147 (57%) Frame = +3 Query: 1446 DNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEMLDH 1625 +++ ++K +G G G V L S ++A+K++ +I R ER+I+ + Sbjct: 90 EDYDVVKVIGRGAFGEVQLVRHKASQKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANS 149 Query: 1626 PFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALEYLH 1805 P++ L+ F D +VMEY PGGDL L PE A+FY AEV+LAL+ +H Sbjct: 150 PWVVQLFCAFQDDKYLYMVMEYMPGGDLVNLMSNY---DVPEKWAKFYTAEVVLALDAIH 206 Query: 1806 MLGVIYRDLKPENILVRDDGHIMLSDF 1886 +G+I+RD+KP+N+L+ GH+ L+DF Sbjct: 207 SMGLIHRDVKPDNMLLDKHGHLKLADF 233 Score = 87.0 bits (214), Expect = 4e-16 Identities = 53/122 (43%), Positives = 73/122 (59%), Gaps = 8/122 (6%) Frame = +3 Query: 2145 VGTHEYLAPEIIK---GDGH-GSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVV--S 2306 VGT +Y++PE++K GDG+ G DWW+ GVFL+E+L G TPF T + ++ Sbjct: 251 VGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLFEMLVGDTPFYADSLVGTYSKIMDHK 310 Query: 2307 QNLRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPFFEG--LNWALIRSVA 2480 +L FP++ +S +AK+LI L + E RLG G EIKQHPFF+ NW IR A Sbjct: 311 NSLCFPEDAEISKHAKNLICAFLT-DREVRLGR-NGVEEIKQHPFFKNDQWNWDNIRETA 368 Query: 2481 PP 2486 P Sbjct: 369 AP 370
>Q8C0P0:MASTL_MOUSE Microtubule-associated serine/threonine-protein kinase-like - Mus| musculus (Mouse) Length = 865 Score = 97.1 bits (240), Expect = 4e-19 Identities = 56/151 (37%), Positives = 88/151 (58%) Frame = +3 Query: 1434 PLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILE 1613 P ++ F ++K + G G VYL + L+A+KV+ ++++ + QAER+ L Sbjct: 28 PPSIEEFTIVKPISRGAFGKVYLGQ--KGGKLYAVKVVKKADMVNKNMTHQVQAERDALA 85 Query: 1614 MLDHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLAL 1793 + PF+ LY + + L+MEY GGD+ L F E A Y++EV LAL Sbjct: 86 LSKSPFVVHLYYSLQSASNIYLIMEYLIGGDVKSLLHIYG--YFDEEMAIKYISEVALAL 143 Query: 1794 EYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 +YLH G+I+RDLKP+N+L+ ++GHI L+DF Sbjct: 144 DYLHRHGIIHRDLKPDNMLISNEGHIKLTDF 174 Score = 79.3 bits (194), Expect = 8e-14 Identities = 40/115 (34%), Positives = 62/115 (53%), Gaps = 1/115 (0%) Frame = +3 Query: 2145 VGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQNLRFP 2324 +GT +YLAPE++ G HG AVDWW GV L+E L G PF + N++ +++ +P Sbjct: 725 LGTPDYLAPELLLGTAHGPAVDWWALGVCLFEFLTGIPPFNDETPQQVFQNILKRDIPWP 784 Query: 2325 D-NPVVSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPFFEGLNWALIRSVAPP 2486 + +S NA+ + LL + R G E+KQHP F ++W ++ P Sbjct: 785 EGEEKLSDNAQSAMDMLLTIDDSKR----AGMRELKQHPLFSEVDWENLQHQTMP 835
>Q62833:GRK5_RAT G protein-coupled receptor kinase 5 - Rattus norvegicus (Rat)| Length = 590 Score = 97.1 bits (240), Expect = 4e-19 Identities = 59/156 (37%), Positives = 86/156 (55%), Gaps = 2/156 (1%) Frame = +3 Query: 1422 LQQGPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAER 1601 L++ P+ + FR + LG G G V ++ + ++A K ++ + + RK A E+ Sbjct: 176 LERQPVTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKRLEKKRIKKRKGESMALNEK 235 Query: 1602 EILEMLDHPFLPTLYAHFTTDNLSCLVMEYCPGGDL--HVLRQRQPGRSFPEPSARFYVA 1775 +ILE ++ F+ L + T + CLV+ GGDL H+ PG F E A FY A Sbjct: 236 QILEKVNSQFVVNLAYAYETKDALCLVLTIMNGGDLKFHIYNMGNPG--FEEERALFYAA 293 Query: 1776 EVLLALEYLHMLGVIYRDLKPENILVRDDGHIMLSD 1883 E+L LE LH +YRDLKPENIL+ D GHI +SD Sbjct: 294 EILCGLEDLHRENTVYRDLKPENILLDDYGHIRISD 329 Score = 75.9 bits (185), Expect = 9e-13 Identities = 40/108 (37%), Positives = 61/108 (56%), Gaps = 3/108 (2%) Frame = +3 Query: 2145 VGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQNLRFP 2324 VGT Y+APE++ +G + D+W G +YE++ G++PFRG V + L Sbjct: 346 VGTVGYMAPEVLNNQRYGLSPDYWGLGCLIYEMIEGQSPFRGRKEKVKREEVDRRVLETE 405 Query: 2325 D--NPVVSSNAKDLIRGLLVKEPENRLGTL-RGAAEIKQHPFFEGLNW 2459 + +P S AK + LL K+ + RLG GAAE+K+HPFF +N+ Sbjct: 406 EVYSPKFSEEAKSICNMLLTKDSKQRLGCQEEGAAEVKRHPFFRNMNF 453
>Q8VEB1:GRK5_MOUSE G protein-coupled receptor kinase 5 - Mus musculus (Mouse)| Length = 590 Score = 97.1 bits (240), Expect = 4e-19 Identities = 59/156 (37%), Positives = 86/156 (55%), Gaps = 2/156 (1%) Frame = +3 Query: 1422 LQQGPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAER 1601 L++ P+ + FR + LG G G V ++ + ++A K ++ + + RK A E+ Sbjct: 176 LERQPVTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKRLEKKRIKKRKGESMALNEK 235 Query: 1602 EILEMLDHPFLPTLYAHFTTDNLSCLVMEYCPGGDL--HVLRQRQPGRSFPEPSARFYVA 1775 +ILE ++ F+ L + T + CLV+ GGDL H+ PG F E A FY A Sbjct: 236 QILEKVNSQFVVNLAYAYETKDALCLVLTIMNGGDLKFHIYNMGNPG--FEEERALFYAA 293 Query: 1776 EVLLALEYLHMLGVIYRDLKPENILVRDDGHIMLSD 1883 E+L LE LH +YRDLKPENIL+ D GHI +SD Sbjct: 294 EILCGLEDLHRENTVYRDLKPENILLDDYGHIRISD 329 Score = 72.8 bits (177), Expect = 7e-12 Identities = 39/108 (36%), Positives = 60/108 (55%), Gaps = 3/108 (2%) Frame = +3 Query: 2145 VGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQNLRFP 2324 VGT Y+APE++ +G + D+W G +YE++ G++PFRG V + L Sbjct: 346 VGTVGYMAPEVLNNQRYGLSPDYWGLGCLIYEMIEGQSPFRGRKEKVKREEVDRRVLETE 405 Query: 2325 D--NPVVSSNAKDLIRGLLVKEPENRLGTL-RGAAEIKQHPFFEGLNW 2459 + + S AK + LL K+ + RLG GAAE+K+HPFF +N+ Sbjct: 406 EVYSSKFSEEAKSICNMLLTKDSKQRLGCQEEGAAEVKRHPFFRNMNF 453
>P34947:GRK5_HUMAN G protein-coupled receptor kinase 5 - Homo sapiens (Human)| Length = 590 Score = 97.1 bits (240), Expect = 4e-19 Identities = 59/156 (37%), Positives = 86/156 (55%), Gaps = 2/156 (1%) Frame = +3 Query: 1422 LQQGPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAER 1601 L++ P+ + FR + LG G G V ++ + ++A K ++ + + RK A E+ Sbjct: 176 LERQPVTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKRLEKKRIKKRKGESMALNEK 235 Query: 1602 EILEMLDHPFLPTLYAHFTTDNLSCLVMEYCPGGDL--HVLRQRQPGRSFPEPSARFYVA 1775 +ILE ++ F+ L + T + CLV+ GGDL H+ PG F E A FY A Sbjct: 236 QILEKVNSQFVVNLAYAYETKDALCLVLTIMNGGDLKFHIYNMGNPG--FEEERALFYAA 293 Query: 1776 EVLLALEYLHMLGVIYRDLKPENILVRDDGHIMLSD 1883 E+L LE LH +YRDLKPENIL+ D GHI +SD Sbjct: 294 EILCGLEDLHRENTVYRDLKPENILLDDYGHIRISD 329 Score = 73.2 bits (178), Expect = 6e-12 Identities = 39/108 (36%), Positives = 61/108 (56%), Gaps = 3/108 (2%) Frame = +3 Query: 2145 VGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQNLRFP 2324 VGT Y+APE++ +G + D+W G +YE++ G++PFRG V + L Sbjct: 346 VGTVGYMAPEVLNNQRYGLSPDYWGLGCLIYEMIEGQSPFRGRKEKVKREEVDRRVLETE 405 Query: 2325 D--NPVVSSNAKDLIRGLLVKEPENRLGTL-RGAAEIKQHPFFEGLNW 2459 + + S AK + + LL K+ + RLG GAAE+K+HPFF +N+ Sbjct: 406 EVYSHKFSEEAKSICKMLLTKDAKQRLGCQEEGAAEVKRHPFFRNMNF 453
>Q86UX6:ST32C_HUMAN Serine/threonine-protein kinase 32C - Homo sapiens (Human)| Length = 486 Score = 96.7 bits (239), Expect = 5e-19 Identities = 51/151 (33%), Positives = 88/151 (58%) Frame = +3 Query: 1437 LGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEM 1616 + D+F++L+ +G G G V + + D++ ++A+K M+ + I R ++ E EIL+ Sbjct: 88 VNFDHFQILRAIGKGSFGKVCIVQKRDTEKMYAMKYMNKQQCIERDEVRNVFRELEILQE 147 Query: 1617 LDHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALE 1796 ++H FL L+ F + +V++ GGDL Q F E + R Y+ E+ LAL+ Sbjct: 148 IEHVFLVNLWYSFQDEEDMFMVVDLLLGGDLRY--HLQQNVQFSEDTVRLYICEMALALD 205 Query: 1797 YLHMLGVIYRDLKPENILVRDDGHIMLSDFD 1889 YL +I+RD+KP+NIL+ + GH L+DF+ Sbjct: 206 YLRGQHIIHRDVKPDNILLDERGHAHLTDFN 236 Score = 57.8 bits (138), Expect = 2e-07 Identities = 39/117 (33%), Positives = 56/117 (47%), Gaps = 7/117 (5%) Frame = +3 Query: 2130 RSNSFVGTHEYLAPEIIK-----GDGHGSAVDWWTFGVFLYELLYGRTPF--RGPGNDET 2288 R+ + GT Y+APEI G G+ VDWW+ GV YELL G P+ E+ Sbjct: 246 RATALAGTKPYMAPEIFHSFVNGGTGYSFEVDWWSVGVMAYELLRGWRPYDIHSSNAVES 305 Query: 2289 LANVVSQNLRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPFFEGLNW 2459 L + S + P S L+R LL PE+RL +L+ +++ P G+ W Sbjct: 306 LVQLFS-TVSVQYVPTWSKEMVALLRKLLTVNPEHRLSSLQ---DVQAAPALAGVLW 358
>Q63644:ROCK1_RAT Rho-associated protein kinase 1 - Rattus norvegicus (Rat)| Length = 1369 Score = 96.7 bits (239), Expect = 5e-19 Identities = 53/147 (36%), Positives = 84/147 (57%) Frame = +3 Query: 1446 DNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEMLDH 1625 +++ ++K +G G G V L + ++A+K++ +I R ER+I+ + Sbjct: 74 EDYEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANS 133 Query: 1626 PFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALEYLH 1805 P++ L+ F D +VMEY PGGDL L PE ARFY AEV+LAL+ +H Sbjct: 134 PWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNY---DVPEKWARFYTAEVVLALDAIH 190 Query: 1806 MLGVIYRDLKPENILVRDDGHIMLSDF 1886 +G I+RD+KP+N+L+ GH+ L+DF Sbjct: 191 SMGFIHRDVKPDNMLLDKSGHLKLADF 217 Score = 84.7 bits (208), Expect = 2e-15 Identities = 54/127 (42%), Positives = 76/127 (59%), Gaps = 9/127 (7%) Frame = +3 Query: 2130 RSNSFVGTHEYLAPEIIK---GDGH-GSAVDWWTFGVFLYELLYGRTPFRGPGNDETLAN 2297 R ++ VGT +Y++PE++K GDG+ G DWW+ GVFLYE+L G TPF T + Sbjct: 230 RCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSK 289 Query: 2298 VVS--QNLRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPFFEGLNWA--- 2462 +++ +L FPD+ +S AK+LI L + E RLG G EIK+H FF+ WA Sbjct: 290 IMNHKNSLTFPDDNDISKEAKNLICAFLT-DREVRLGR-NGVEEIKRHLFFKNDQWAWET 347 Query: 2463 LIRSVAP 2483 L +VAP Sbjct: 348 LRDTVAP 354
>O77819:ROCK1_RABIT Rho-associated protein kinase 1 - Oryctolagus cuniculus (Rabbit)| Length = 1354 Score = 96.7 bits (239), Expect = 5e-19 Identities = 53/147 (36%), Positives = 84/147 (57%) Frame = +3 Query: 1446 DNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEMLDH 1625 +++ ++K +G G G V L + ++A+K++ +I R ER+I+ + Sbjct: 74 EDYEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANS 133 Query: 1626 PFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALEYLH 1805 P++ L+ F D +VMEY PGGDL L PE ARFY AEV+LAL+ +H Sbjct: 134 PWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNY---DVPEKWARFYTAEVVLALDAIH 190 Query: 1806 MLGVIYRDLKPENILVRDDGHIMLSDF 1886 +G I+RD+KP+N+L+ GH+ L+DF Sbjct: 191 SMGFIHRDVKPDNMLLDKSGHLKLADF 217 Score = 84.7 bits (208), Expect = 2e-15 Identities = 54/127 (42%), Positives = 76/127 (59%), Gaps = 9/127 (7%) Frame = +3 Query: 2130 RSNSFVGTHEYLAPEIIK---GDGH-GSAVDWWTFGVFLYELLYGRTPFRGPGNDETLAN 2297 R ++ VGT +Y++PE++K GDG+ G DWW+ GVFLYE+L G TPF T + Sbjct: 230 RCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSK 289 Query: 2298 VVS--QNLRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPFFEGLNWA--- 2462 +++ +L FPD+ +S AK+LI L + E RLG G EIK+H FF+ WA Sbjct: 290 IMNHKNSLTFPDDNDISKEAKNLICAFLT-DREVRLGR-NGVEEIKRHLFFKNDQWAWET 347 Query: 2463 LIRSVAP 2483 L +VAP Sbjct: 348 LRDTVAP 354
>P70335:ROCK1_MOUSE Rho-associated protein kinase 1 - Mus musculus (Mouse)| Length = 1354 Score = 96.7 bits (239), Expect = 5e-19 Identities = 53/147 (36%), Positives = 84/147 (57%) Frame = +3 Query: 1446 DNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEMLDH 1625 +++ ++K +G G G V L + ++A+K++ +I R ER+I+ + Sbjct: 74 EDYEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANS 133 Query: 1626 PFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALEYLH 1805 P++ L+ F D +VMEY PGGDL L PE ARFY AEV+LAL+ +H Sbjct: 134 PWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNY---DVPEKWARFYTAEVVLALDAIH 190 Query: 1806 MLGVIYRDLKPENILVRDDGHIMLSDF 1886 +G I+RD+KP+N+L+ GH+ L+DF Sbjct: 191 SMGFIHRDVKPDNMLLDKSGHLKLADF 217 Score = 84.7 bits (208), Expect = 2e-15 Identities = 54/127 (42%), Positives = 76/127 (59%), Gaps = 9/127 (7%) Frame = +3 Query: 2130 RSNSFVGTHEYLAPEIIK---GDGH-GSAVDWWTFGVFLYELLYGRTPFRGPGNDETLAN 2297 R ++ VGT +Y++PE++K GDG+ G DWW+ GVFLYE+L G TPF T + Sbjct: 230 RCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSK 289 Query: 2298 VVS--QNLRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPFFEGLNWA--- 2462 +++ +L FPD+ +S AK+LI L + E RLG G EIK+H FF+ WA Sbjct: 290 IMNHKNSLTFPDDNDISKEAKNLICAFLT-DREVRLGR-NGVEEIKRHLFFKNDQWAWET 347 Query: 2463 LIRSVAP 2483 L +VAP Sbjct: 348 LRDTVAP 354
>Q13464:ROCK1_HUMAN Rho-associated protein kinase 1 - Homo sapiens (Human)| Length = 1354 Score = 96.7 bits (239), Expect = 5e-19 Identities = 53/147 (36%), Positives = 84/147 (57%) Frame = +3 Query: 1446 DNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEMLDH 1625 +++ ++K +G G G V L + ++A+K++ +I R ER+I+ + Sbjct: 74 EDYEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANS 133 Query: 1626 PFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALEYLH 1805 P++ L+ F D +VMEY PGGDL L PE ARFY AEV+LAL+ +H Sbjct: 134 PWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNY---DVPEKWARFYTAEVVLALDAIH 190 Query: 1806 MLGVIYRDLKPENILVRDDGHIMLSDF 1886 +G I+RD+KP+N+L+ GH+ L+DF Sbjct: 191 SMGFIHRDVKPDNMLLDKSGHLKLADF 217 Score = 84.7 bits (208), Expect = 2e-15 Identities = 54/127 (42%), Positives = 76/127 (59%), Gaps = 9/127 (7%) Frame = +3 Query: 2130 RSNSFVGTHEYLAPEIIK---GDGH-GSAVDWWTFGVFLYELLYGRTPFRGPGNDETLAN 2297 R ++ VGT +Y++PE++K GDG+ G DWW+ GVFLYE+L G TPF T + Sbjct: 230 RCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSK 289 Query: 2298 VVS--QNLRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPFFEGLNWA--- 2462 +++ +L FPD+ +S AK+LI L + E RLG G EIK+H FF+ WA Sbjct: 290 IMNHKNSLTFPDDNDISKEAKNLICAFLT-DREVRLGR-NGVEEIKRHLFFKNDQWAWET 347 Query: 2463 LIRSVAP 2483 L +VAP Sbjct: 348 LRDTVAP 354
>O08874:PKN2_RAT Serine/threonine-protein kinase N2 - Rattus norvegicus (Rat)| Length = 985 Score = 96.7 bits (239), Expect = 5e-19 Identities = 58/157 (36%), Positives = 86/157 (54%), Gaps = 3/157 (1%) Frame = +3 Query: 1425 QQGPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAERE 1604 Q+ L +FR LG G G V LAE ++ +FA+K + +++R ++ E+ Sbjct: 649 QRFQFNLQDFRCCAVLGRGHFGKVLLAEYKHTNEMFAIKALKKGDIVARDEVDSLMCEKR 708 Query: 1605 ILEMLD---HPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVA 1775 I E ++ HPFL L+A F T C VMEY GGDL + F EP A FY A Sbjct: 709 IFETVNSVRHPFLVNLFACFQTKEHVCFVMEYAAGGDLMMHIHTDV---FSEPRAVFYAA 765 Query: 1776 EVLLALEYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 V+L L+YLH ++YRDLK +N+L+ + + ++DF Sbjct: 766 CVVLGLQYLHEHKIVYRDLKLDNLLLDTEASVKIADF 802 Score = 96.3 bits (238), Expect = 6e-19 Identities = 48/122 (39%), Positives = 76/122 (62%), Gaps = 3/122 (2%) Frame = +3 Query: 2130 RSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQ 2309 R+++F GT E+LAPE++ + AVDWW GV +YE+L G +PF G +E ++V+ Sbjct: 814 RTSTFCGTPEFLAPEVLTETSYTRAVDWWGLGVLIYEMLVGESPFPGDDEEEVFDSIVND 873 Query: 2310 NLRFPDNPVVSSNAKDLIRGLLVKEPENRLGT-LRGAAEIKQHPFFEGLNWA--LIRSVA 2480 +R+P +S+ A ++R LL + PE RLG + A ++K+HPFF +W+ L + V Sbjct: 874 EVRYP--RFLSTEAISIMRRLLRRNPERRLGAGEKDAEDVKKHPFFRLTDWSALLDKKVK 931 Query: 2481 PP 2486 PP Sbjct: 932 PP 933
>Q7TT49:MRCKB_RAT Serine/threonine-protein kinase MRCK beta - Rattus norvegicus (Rat)| Length = 1713 Score = 96.7 bits (239), Expect = 5e-19 Identities = 48/147 (32%), Positives = 92/147 (62%) Frame = +3 Query: 1446 DNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEMLDH 1625 ++F ++K +G G G V + ++ +++ ++A+K+++ ++ R + + ER++L D Sbjct: 74 EDFEIIKVIGRGAFGEVAVVKMKNTERIYAMKILNKWEMLKRAETACFREERDVLVNGDC 133 Query: 1626 PFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALEYLH 1805 ++ L+ F +N LVM+Y GGDL L + + PE ARFY+ E++LA++ +H Sbjct: 134 QWITALHYAFQDENYLYLVMDYYVGGDLLTLLSKFEDK-LPEDMARFYIGEMVLAIDSIH 192 Query: 1806 MLGVIYRDLKPENILVRDDGHIMLSDF 1886 L ++RD+KP+N+L+ +GHI L+DF Sbjct: 193 QLHYVHRDIKPDNVLLDVNGHIRLADF 219 Score = 90.9 bits (224), Expect = 3e-17 Identities = 53/127 (41%), Positives = 76/127 (59%), Gaps = 8/127 (6%) Frame = +3 Query: 2130 RSNSFVGTHEYLAPEIIKG--DG---HGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLA 2294 +S+ VGT +Y++PEI++ DG +G DWW+ GV +YE+LYG TPF ET Sbjct: 232 QSSVAVGTPDYISPEILQAMEDGMGKYGPECDWWSLGVCMYEMLYGETPFYAESLVETYG 291 Query: 2295 NVVS--QNLRFPDNPV-VSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPFFEGLNWAL 2465 +++ + +FP + VS AKDLI+ L+ E RLG G + K+H FFEGLNW Sbjct: 292 KIMNHEERFQFPSHVTDVSEEAKDLIQRLICSR-ERRLGQ-NGIEDFKKHAFFEGLNWEN 349 Query: 2466 IRSVAPP 2486 IR++ P Sbjct: 350 IRNLEAP 356
>P32866:GPRK2_DROME G protein-coupled receptor kinase 2 - Drosophila melanogaster (Fruit| fly) Length = 714 Score = 96.7 bits (239), Expect = 5e-19 Identities = 56/157 (35%), Positives = 87/157 (55%), Gaps = 3/157 (1%) Frame = +3 Query: 1422 LQQGPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAER 1601 L+ P+ FR+ + LG G G V ++ + ++A K ++ + + RK E+ Sbjct: 299 LEAQPITYKTFRMYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGESMVLIEK 358 Query: 1602 EILEMLDHPFLPTLYAHFTTDNLSCLVMEYCPGGDL--HVLRQR-QPGRSFPEPSARFYV 1772 +IL+ ++ PF+ L + T + CLV+ GGDL H+ +PG F ARFY Sbjct: 359 QILQKINSPFVVNLAYAYETKDALCLVLTIMNGGDLKFHIYNMGGEPG--FELERARFYA 416 Query: 1773 AEVLLALEYLHMLGVIYRDLKPENILVRDDGHIMLSD 1883 AEV L++LH G++YRD KPENIL+ D GH+ +SD Sbjct: 417 AEVACGLQHLHKQGIVYRDCKPENILLDDHGHVRISD 453 Score = 61.6 bits (148), Expect = 2e-08 Identities = 39/123 (31%), Positives = 61/123 (49%), Gaps = 9/123 (7%) Frame = +3 Query: 2145 VGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQNLRFP 2324 VGT Y+APE+I + + + DW++FG LYE++ G+ PFR V + P Sbjct: 470 VGTVGYMAPEVIDNEKYAFSPDWFSFGCLLYEMIEGQAPFRMRKEKVKREEVDRRVKEDP 529 Query: 2325 D--NPVVSSNAKDLIRGLLVKEPENRLGTLR---GAAEIKQHPFFEG--LNWALIRS--V 2477 + + + AK + + LL K + RLG G ++ HPFF LNW + + + Sbjct: 530 EKYSSKFNDEAKSMCQQLLAKSIKQRLGCRNGRMGGQDVMAHPFFHSTQLNWRRLEAGML 589 Query: 2478 APP 2486 PP Sbjct: 590 EPP 592
>O75116:ROCK2_HUMAN Rho-associated protein kinase 2 - Homo sapiens (Human)| Length = 1388 Score = 96.3 bits (238), Expect = 6e-19 Identities = 53/147 (36%), Positives = 85/147 (57%) Frame = +3 Query: 1446 DNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEMLDH 1625 +++ ++K +G G G V L S ++A+K++ +I R ER+I+ + Sbjct: 90 EDYDVVKVIGRGAFGEVQLVRHKASQKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANS 149 Query: 1626 PFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALEYLH 1805 P++ L+ F D +VMEY PGGDL L PE A+FY AEV+LAL+ +H Sbjct: 150 PWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNY---DVPEKWAKFYTAEVVLALDAIH 206 Query: 1806 MLGVIYRDLKPENILVRDDGHIMLSDF 1886 +G+I+RD+KP+N+L+ GH+ L+DF Sbjct: 207 SMGLIHRDVKPDNMLLDKHGHLKLADF 233 Score = 85.5 bits (210), Expect = 1e-15 Identities = 52/122 (42%), Positives = 73/122 (59%), Gaps = 8/122 (6%) Frame = +3 Query: 2145 VGTHEYLAPEIIK---GDG-HGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVV--S 2306 VGT +Y++PE++K GDG +G DWW+ GVFLYE+L G TPF T + ++ Sbjct: 251 VGTPDYISPEVLKSQGGDGFYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMDHK 310 Query: 2307 QNLRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPFFEG--LNWALIRSVA 2480 +L FP++ +S +AK+LI L + E RLG G EI+QHPFF+ +W IR A Sbjct: 311 NSLCFPEDAEISKHAKNLICAFLT-DREVRLGR-NGVEEIRQHPFFKNDQWHWDNIRETA 368 Query: 2481 PP 2486 P Sbjct: 369 AP 370
>Q7TT50:MRCKB_MOUSE Serine/threonine-protein kinase MRCK beta - Mus musculus (Mouse)| Length = 1713 Score = 96.3 bits (238), Expect = 6e-19 Identities = 48/147 (32%), Positives = 92/147 (62%) Frame = +3 Query: 1446 DNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEMLDH 1625 ++F ++K +G G G V + ++ +++ ++A+K+++ ++ R + + ER++L D Sbjct: 74 EDFEIIKVIGRGAFGEVAVVKMRNTERIYAMKILNKWEMLKRAETACFREERDVLVNGDC 133 Query: 1626 PFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALEYLH 1805 ++ L+ F +N LVM+Y GGDL L + + PE ARFY+ E++LA++ +H Sbjct: 134 QWITALHYAFQDENYLYLVMDYYVGGDLLTLLSKFEDK-LPEDMARFYIGEMVLAIDSIH 192 Query: 1806 MLGVIYRDLKPENILVRDDGHIMLSDF 1886 L ++RD+KP+N+L+ +GHI L+DF Sbjct: 193 QLHYVHRDIKPDNVLLDVNGHIRLADF 219 Score = 90.9 bits (224), Expect = 3e-17 Identities = 53/127 (41%), Positives = 76/127 (59%), Gaps = 8/127 (6%) Frame = +3 Query: 2130 RSNSFVGTHEYLAPEIIKG--DG---HGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLA 2294 +S+ VGT +Y++PEI++ DG +G DWW+ GV +YE+LYG TPF ET Sbjct: 232 QSSVAVGTPDYISPEILQAMEDGMGKYGPECDWWSLGVCMYEMLYGETPFYAESLVETYG 291 Query: 2295 NVVS--QNLRFPDNPV-VSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPFFEGLNWAL 2465 +++ + +FP + VS AKDLI+ L+ E RLG G + K+H FFEGLNW Sbjct: 292 KIMNHEERFQFPSHVTDVSEEAKDLIQRLICSR-ERRLGQ-NGIEDFKKHAFFEGLNWEN 349 Query: 2466 IRSVAPP 2486 IR++ P Sbjct: 350 IRNLEAP 356
>Q9Y5S2:MRCKB_HUMAN Serine/threonine-protein kinase MRCK beta - Homo sapiens (Human)| Length = 1711 Score = 95.9 bits (237), Expect = 8e-19 Identities = 48/147 (32%), Positives = 92/147 (62%) Frame = +3 Query: 1446 DNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEMLDH 1625 ++F ++K +G G G V + ++ +++ ++A+K+++ ++ R + + ER++L D Sbjct: 74 EDFEIIKVIGRGAFGEVAVVKMKNTERIYAMKILNKWEMLKRAETACFREERDVLVNGDC 133 Query: 1626 PFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALEYLH 1805 ++ L+ F +N LVM+Y GGDL L + + PE ARFY+ E++LA++ +H Sbjct: 134 QWITALHYAFQDENHLYLVMDYYVGGDLLTLLSKFEDK-LPEDMARFYIGEMVLAIDSIH 192 Query: 1806 MLGVIYRDLKPENILVRDDGHIMLSDF 1886 L ++RD+KP+N+L+ +GHI L+DF Sbjct: 193 QLHYVHRDIKPDNVLLDVNGHIRLADF 219 Score = 90.9 bits (224), Expect = 3e-17 Identities = 53/127 (41%), Positives = 76/127 (59%), Gaps = 8/127 (6%) Frame = +3 Query: 2130 RSNSFVGTHEYLAPEIIKG--DG---HGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLA 2294 +S+ VGT +Y++PEI++ DG +G DWW+ GV +YE+LYG TPF ET Sbjct: 232 QSSVAVGTPDYISPEILQAMEDGMGKYGPECDWWSLGVCMYEMLYGETPFYAESLVETYG 291 Query: 2295 NVVS--QNLRFPDNPV-VSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPFFEGLNWAL 2465 +++ + +FP + VS AKDLI+ L+ E RLG G + K+H FFEGLNW Sbjct: 292 KIMNHEERFQFPSHVTDVSEEAKDLIQRLICSR-ERRLGQ-NGIEDFKKHAFFEGLNWEN 349 Query: 2466 IRSVAPP 2486 IR++ P Sbjct: 350 IRNLEAP 356
>O01427:AIR2_CAEEL Aurora/Ipl1-related protein kinase 2 - Caenorhabditis elegans| Length = 305 Score = 95.9 bits (237), Expect = 8e-19 Identities = 55/152 (36%), Positives = 83/152 (54%) Frame = +3 Query: 1431 GPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREIL 1610 G +++F + + LG G G+VYLA A+KV+ LIS + + E EI Sbjct: 23 GKFTINDFEIGRPLGKGKFGSVYLARTKTGHFHVAIKVLFKSQLISGGVEHQLEREIEIQ 82 Query: 1611 EMLDHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLA 1790 L+HP + LY +F LV+EY PGG+++ +Q + F EP+A Y+ E+ A Sbjct: 83 SHLNHPNIIKLYTYFWDAKKIYLVLEYAPGGEMY--KQLTVSKRFSEPTAAKYMYEIADA 140 Query: 1791 LEYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 L Y H VI+RD+KPEN+L+ G + + DF Sbjct: 141 LSYCHRKNVIHRDIKPENLLIGSQGELKIGDF 172 Score = 75.1 bits (183), Expect = 1e-12 Identities = 42/115 (36%), Positives = 63/115 (54%) Frame = +3 Query: 2130 RSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQ 2309 + + GT +YL PE++ G H AVD W GV YE L G+ PF +T A + + Sbjct: 182 KRQTMCGTMDYLPPEMVNGADHSDAVDLWAIGVLCYEFLVGKPPFEHEDQSKTYAAIKAA 241 Query: 2310 NLRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPFFEGLNWALIRS 2474 +PD+ V A+DLI LLV +P+ R TL ++K+H + +G+ A IR+ Sbjct: 242 RFTYPDS--VKKGARDLIGRLLVVDPKARC-TLE---QVKEHYWIQGMMEAKIRA 290
>Q8WU08:ST32A_HUMAN Serine/threonine-protein kinase 32A - Homo sapiens (Human)| Length = 396 Score = 95.5 bits (236), Expect = 1e-18 Identities = 46/151 (30%), Positives = 89/151 (58%) Frame = +3 Query: 1437 LGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEM 1616 + D+F +L+ +G G G V + + D+ ++A+K M+ + + R ++ E +I++ Sbjct: 18 VNFDHFEILRAIGKGSFGKVCIVQKNDTKKMYAMKYMNKQKCVERNEVRNVFKELQIMQG 77 Query: 1617 LDHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALE 1796 L+HPFL L+ F + +V++ GGDL Q F E + + ++ E+++AL+ Sbjct: 78 LEHPFLVNLWYSFQDEEDMFMVVDLLLGGDLRY--HLQQNVHFKEETVKLFICELVMALD 135 Query: 1797 YLHMLGVIYRDLKPENILVRDDGHIMLSDFD 1889 YL +I+RD+KP+NIL+ + GH+ ++DF+ Sbjct: 136 YLQNQRIIHRDMKPDNILLDEHGHVHITDFN 166 Score = 63.9 bits (154), Expect = 3e-09 Identities = 37/120 (30%), Positives = 58/120 (48%), Gaps = 6/120 (5%) Frame = +3 Query: 2118 PTEARSNSFVGTHEYLAPEII---KGDGHGSAVDWWTFGVFLYELLYGRTPFR---GPGN 2279 P E + + GT Y+APE+ KG G+ AVDWW+ GV YELL GR P+ + Sbjct: 172 PRETQITTMAGTKPYMAPEMFSSRKGAGYSFAVDWWSLGVTAYELLRGRRPYHIRSSTSS 231 Query: 2280 DETLANVVSQNLRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPFFEGLNW 2459 E + + + +P S L++ LL P+ R L ++++ P+ +NW Sbjct: 232 KEIVHTFETTVVTYPS--AWSQEMVSLLKKLLEPNPDQRFSQL---SDVQNFPYMNDINW 286
>P38938:CEK1_SCHPO Serine/threonine-protein kinase cek1 - Schizosaccharomyces pombe| (Fission yeast) Length = 1338 Score = 95.5 bits (236), Expect = 1e-18 Identities = 49/120 (40%), Positives = 67/120 (55%), Gaps = 2/120 (1%) Frame = +3 Query: 2133 SNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQN 2312 S F+GT +Y+APE+I G+ A DWW+ G ++E L+G PF D+ N++++ Sbjct: 854 SKRFIGTPDYIAPEVILGNPGIKASDWWSLGCVVFEFLFGYPPFNAETPDQVFQNILARR 913 Query: 2313 LRFPDN--PVVSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPFFEGLNWALIRSVAPP 2486 + +P SS A DLI LL P NRLG G EIK HPFF+ +NW I PP Sbjct: 914 INWPAEVFTAESSVALDLIDRLLCMNPANRLGA-NGVEEIKAHPFFKSVNWDTILEEDPP 972 Score = 94.0 bits (232), Expect = 3e-18 Identities = 53/149 (35%), Positives = 88/149 (59%), Gaps = 1/149 (0%) Frame = +3 Query: 1443 LDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREIL-EML 1619 ++++++LK + G G+VYLA+ + FA+K++ +I++ +++ +AER IL Sbjct: 586 INDYKILKPISKGAFGSVYLAQKRTTGDYFAIKILKKSNMIAKNQVINVRAERAILMSQG 645 Query: 1620 DHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALEY 1799 + PF+ LY F + + LVMEY GGD L + R Y+AE +L L Sbjct: 646 ESPFVAKLYYTFQSKDYLYLVMEYLNGGDCGSLLKTMGVLDLDW--IRTYIAETVLCLGD 703 Query: 1800 LHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 LH G+I+RD+KPEN+L+ +GH+ L+DF Sbjct: 704 LHDRGIIHRDIKPENLLISQNGHLKLTDF 732
>P34100:PKD1_DICDI Developmentally-regulated protein kinase 1 - Dictyostelium discoideum| (Slime mold) Length = 416 Score = 95.1 bits (235), Expect = 1e-18 Identities = 55/149 (36%), Positives = 76/149 (51%), Gaps = 1/149 (0%) Frame = +3 Query: 1443 LDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEMLD 1622 + +F LG G GT L S F K + E ++ K E I+ + Sbjct: 33 ISDFNFYGSLGSGSFGTAKLCRHRGSGLFFCSKTLRRETIVHEKHKEHVNNEINIMLNIS 92 Query: 1623 HPFLPTLYAHFTTDNLSCLVMEYCPGGDL-HVLRQRQPGRSFPEPSARFYVAEVLLALEY 1799 HP++ Y+ F T +MEY DL H LR + F E + + VAE++LA+EY Sbjct: 93 HPYIVKTYSTFNTPTKIHFIMEYAGKKDLFHHLRAN---KCFTEQTTKLIVAEIVLAIEY 149 Query: 1800 LHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 LH +IYRDLKPENIL+ + GHI L+DF Sbjct: 150 LHAENIIYRDLKPENILIDEKGHIKLTDF 178 Score = 80.5 bits (197), Expect = 4e-14 Identities = 44/115 (38%), Positives = 63/115 (54%), Gaps = 1/115 (0%) Frame = +3 Query: 2133 SNSFVGTHEYLAPEIIKG-DGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQ 2309 ++S GT +Y+APEI+ +GHG VDWW GV +YEL+ G+ PF + E+L N + Sbjct: 190 TSSVCGTFDYMAPEILNSSNGHGKPVDWWALGVVVYELVTGKLPF--SNSKESLLNRKAD 247 Query: 2310 NLRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPFFEGLNWALIRS 2474 N +S KD I LL +P RLGT + I+ H +F +NW + S Sbjct: 248 FQLIFQNSYLSDEIKDFIFQLLSVDPSKRLGTF-DSCSIRNHKWFSDINWLHLES 301
>O70291:GRK4_MOUSE G protein-coupled receptor kinase 4 - Mus musculus (Mouse)| Length = 574 Score = 95.1 bits (235), Expect = 1e-18 Identities = 59/156 (37%), Positives = 85/156 (54%), Gaps = 2/156 (1%) Frame = +3 Query: 1422 LQQGPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAER 1601 L++ P+ + FR + LG G G V ++ + ++A K ++ + + RK A E+ Sbjct: 176 LERRPVTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEK 235 Query: 1602 EILEMLDHPFLPTLYAHFTTDNLSCLVMEYCPGGDL--HVLRQRQPGRSFPEPSARFYVA 1775 ILE L F+ +L + T + CLV+ GGDL H+ PG F EP A FY A Sbjct: 236 RILEKLHSRFVVSLAYTYETKDALCLVLTIMNGGDLKYHIYNLGDPG--FEEPRAVFYAA 293 Query: 1776 EVLLALEYLHMLGVIYRDLKPENILVRDDGHIMLSD 1883 E+ LE L ++YRDLKPENIL+ D GHI +SD Sbjct: 294 ELCCGLEDLQRKRIVYRDLKPENILLDDHGHIRISD 329 Score = 72.8 bits (177), Expect = 7e-12 Identities = 39/115 (33%), Positives = 64/115 (55%), Gaps = 5/115 (4%) Frame = +3 Query: 2145 VGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFR----GPGNDETLANVVSQN 2312 VGT Y+APEII + + + DWW G +YE++ G +PFR +E V ++ Sbjct: 346 VGTVGYMAPEIINHEKYTFSPDWWGLGCLIYEMIAGHSPFRKYKEKVNREELERRVKNET 405 Query: 2313 LRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLR-GAAEIKQHPFFEGLNWALIRS 2474 + + S +AK + LL+K+P RLG R G + +KQHP F+ +N++ + + Sbjct: 406 EEYSER--FSEDAKSICSMLLIKDPSKRLGCQRDGVSAVKQHPIFKDINFSRLEA 458
>Q8BGW6:ST32A_MOUSE Serine/threonine-protein kinase 32A - Mus musculus (Mouse)| Length = 398 Score = 94.4 bits (233), Expect = 2e-18 Identities = 46/151 (30%), Positives = 87/151 (57%) Frame = +3 Query: 1437 LGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAEREILEM 1616 + D+F +L+ +G G G V + D+ ++A+K M+ + + R ++ E +I++ Sbjct: 18 VNFDHFEILRAIGKGSFGKVCIVRKNDTKKMYAMKYMNKQKCVERNEVRNVFKELQIMQG 77 Query: 1617 LDHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHVLRQRQPGRSFPEPSARFYVAEVLLALE 1796 L+HPFL L+ F + +V++ GGDL Q F E + + ++ E+ +AL+ Sbjct: 78 LEHPFLVNLWYSFQDEEDMFMVVDLLLGGDLRY--HLQQNVHFQEDTVKLFICELAMALD 135 Query: 1797 YLHMLGVIYRDLKPENILVRDDGHIMLSDFD 1889 YL +I+RD+KP+NIL+ + GH+ ++DF+ Sbjct: 136 YLQSQRIIHRDMKPDNILLDEHGHVHITDFN 166 Score = 62.8 bits (151), Expect = 8e-09 Identities = 39/120 (32%), Positives = 58/120 (48%), Gaps = 6/120 (5%) Frame = +3 Query: 2118 PTEARSNSFVGTHEYLAPEII---KGDGHGSAVDWWTFGVFLYELLYGRTPF--RGPGND 2282 P E R + GT Y+APE+ K G+ AVDWW+ GV YELL GR P+ R + Sbjct: 172 PKETRITTVAGTKPYMAPEMFTSRKETGYSFAVDWWSLGVTAYELLRGRRPYHIRSSTSS 231 Query: 2283 ETLANVVSQNL-RFPDNPVVSSNAKDLIRGLLVKEPENRLGTLRGAAEIKQHPFFEGLNW 2459 + + N+ + +P S L++ LL P+ R L +I+ P+ +NW Sbjct: 232 KEIVNMFETAIVTYPS--AWSQEMVSLLKKLLEPNPDQRFSHL---TDIQNFPYMSDMNW 286
>Q922R0:PRKX_MOUSE Serine/threonine-protein kinase PRKX - Mus musculus (Mouse)| Length = 355 Score = 94.4 bits (233), Expect = 2e-18 Identities = 58/155 (37%), Positives = 87/155 (56%), Gaps = 1/155 (0%) Frame = +3 Query: 1425 QQGPLGLDNFRLLKRLGCGDIGTVYLAELVDSDCLFALKVMDIEYLISRKKMLRAQAERE 1604 Q+ L ++ + +G G G V L + ALK+M I +I K+ Q E+ Sbjct: 37 QKAGHSLQDWDTIATVGTGTFGRVNLVKEKTGRQYCALKIMSIPDVIRLKQEQHVQNEKA 96 Query: 1605 ILEMLDHPFLPTLYAHFTTDNLSCLVMEYCPGGDLHV-LRQRQPGRSFPEPSARFYVAEV 1781 +L+ ++HPFL L + ++ME+ PGG+L LR R GR F ++ FY E+ Sbjct: 97 VLKEINHPFLIKLLWTGHDNRFLYMLMEFVPGGELFTYLRNR--GR-FSSVASVFYATEI 153 Query: 1782 LLALEYLHMLGVIYRDLKPENILVRDDGHIMLSDF 1886 + A+EYLH ++YRDLKPENIL+ +GHI L+DF Sbjct: 154 VCAIEYLHSKEIVYRDLKPENILLDREGHIKLTDF 188 Score = 89.7 bits (221), Expect = 6e-17 Identities = 47/122 (38%), Positives = 71/122 (58%), Gaps = 3/122 (2%) Frame = +3 Query: 2130 RSNSFVGTHEYLAPEIIKGDGHGSAVDWWTFGVFLYELLYGRTPFRGPGNDETLANVVSQ 2309 R+ + GT EYLAPE+I+ GHG AVDWW G+ ++E+L G PF +++ Sbjct: 197 RTWTLCGTPEYLAPEVIQSKGHGRAVDWWALGILIFEMLSGFPPFFDDNPFGIYQKILAC 256 Query: 2310 NLRFPDNPVVSSNAKDLIRGLLVKEPENRLGTLR-GAAEIKQHPFFEGLNWALI--RSVA 2480 + FP + +KDLI+ LLV + RLG ++ GA +IK+H +F G+ W + R + Sbjct: 257 KIDFPRQ--LDFTSKDLIKKLLVVDRTRRLGNMKNGAEDIKRHRWFRGVEWESVPQRKLK 314 Query: 2481 PP 2486 PP Sbjct: 315 PP 316 Database: uniprot_sprot.fasta.out Posted date: Jul 19, 2007 5:58 PM Number of letters in database: 100,686,439 Number of sequences in database: 274,295 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 274295 Number of Hits to DB: 514,049,735 Number of extensions: 11685566 Number of successful extensions: 37114 Number of sequences better than 10.0: 2317 Number of HSP's gapped: 35017 Number of HSP's successfully gapped: 3771 Length of query: 926 Length of database: 100,686,439 Length adjustment: 123 Effective length of query: 803 Effective length of database: 66,948,154 Effective search space: 53759367662 Effective search space used: 53759367662 Neighboring words threshold: 12 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
