>P53223:CAX4_YEAST Dolichyldiphosphatase - Saccharomyces cerevisiae (Baker's yeast)|
          Length = 239
 Score = 53.1 bits (126), Expect = 3e-06
 Identities = 31/114 (27%), Positives = 61/114 (53%), Gaps = 10/114 (8%)
 Frame = +2

Query: 506 GAVANTVLSSVLKKLLNHERPAP--------ALRSDPGMPSSHAQSIFYAATFLVLSVF- 658
           G + N + ++V+K ++   RP           +RS  GMPS+H+Q + +  T+  L ++ 
Sbjct: 66  GQLMNEIFNNVIKNIIKQPRPVSFGASFQNDTIRSGYGMPSAHSQFMGFCFTYNSLKIYT 125

Query: 659 YWLGPNYLAMIIGATTIASASY-LSWLRVSQRLHTVNQILVGATVGSAFSAMWF 817
            W   N+L   I +  +A  S+ + + RV    H ++Q++VG +VG+   +++F
Sbjct: 126 SWKNLNFLEKCIFSGALALLSFCVCFSRVYLHYHNLDQVIVGFSVGALTGSLYF 179

>Q9JMF7:DOPP1_MOUSE Dolichyldiphosphatase 1 - Mus musculus (Mouse)|
          Length = 238

 Score = 46.6 bits (109), Expect = 2e-04
 Identities = 41/173 (23%), Positives = 74/173 (42%), Gaps = 22/173 (12%)
 Frame = +2

Query: 398 THVE----------VALNRMSKWLVSASFAFAALWKHDGEIMWALMGAVANTVLSSVLKK 547
           THVE          +A   +S   V   F    ++K +   +  L G   N  ++ ++K 
Sbjct: 19  THVEYPAGDLSGHLLAYLSLSPIFVVVGFLTLIIFKRELHTISFLGGLALNQGVNWLIKH 78

Query: 548 LLNHERPA----PALRSDPGMPSSHAQSIF----YAATFLVLSVFYWLGPNYLAM----I 691
           ++   RP      A+ +  GMPSSH+Q ++    Y+  FL L +       +L +    +
Sbjct: 79  VIQEPRPCGGPHTAVGTKYGMPSSHSQFMWFFSVYSFLFLYLRMHQTNNARFLDLLWRHV 138

Query: 692 IGATTIASASYLSWLRVSQRLHTVNQILVGATVGSAFSAMWFALWHLLVREAF 850
           +    + +A  +S+ RV    HT +Q+  G   GS  +  WF +   ++   F
Sbjct: 139 LSLGLLTAAFLVSYSRVYLLYHTWSQVFYGGVAGSLMAVAWFIITQEILTPLF 191

>Q86YN1:DOPP1_HUMAN Dolichyldiphosphatase 1 - Homo sapiens (Human)|
          Length = 238

 Score = 46.2 bits (108), Expect = 3e-04
 Identities = 41/162 (25%), Positives = 70/162 (43%), Gaps = 22/162 (13%)
 Frame = +2

Query: 398 THVE----------VALNRMSKWLVSASFAFAALWKHDGEIMWALMGAVANTVLSSVLKK 547
           THVE          +A   +S   V   F    ++K +   +  L G   N  ++ ++K 
Sbjct: 19  THVEYPAGDLSGHLLAYLSLSPVFVIVGFVTLIIFKRELHTISFLGGLALNEGVNWLIKN 78

Query: 548 LLNHERPA----PALRSDPGMPSSHAQSIF----YAATFLVLSVFYWLGPNYLAM----I 691
           ++   RP      A+ +  GMPSSH+Q ++    Y+  FL L +       +L +    +
Sbjct: 79  VIQEPRPCGGPHTAVGTKYGMPSSHSQFMWFFSVYSFLFLYLRMHQTNNARFLDLLWRHV 138

Query: 692 IGATTIASASYLSWLRVSQRLHTVNQILVGATVGSAFSAMWF 817
           +    +A A  +S+ RV    HT +Q+L G   G   +  WF
Sbjct: 139 LSLGLLAVAFLVSYSRVYLLYHTWSQVLYGGIAGGLMAIAWF 180

>Q9IW06:R1AB_CVPPU Replicase polyprotein 1ab - Porcine transmissible gastroenteritis|
            coronavirus (strain Purdue) (TGEV)
          Length = 6684

 Score = 38.9 bits (89), Expect = 0.050
 Identities = 44/215 (20%), Positives = 94/215 (43%), Gaps = 35/215 (16%)
 Frame = +2

Query: 392  RW--THVEVALNRMSKWLVSASF-------AFAALWKHDGEIMWALMGAVAN-------- 520
            RW  T+  ++L   + W  + SF       AF+ L    G+ +  L+ ++          
Sbjct: 3094 RWFVTNTSMSLESYNTWAKTNSFTELSSTDAFSMLAAKTGQSVEKLLDSIVRLNKGFGGR 3153

Query: 521  TVLSSVLKKLLNHERPAPALRSDPGM------------PSSHAQSIFYA--ATFLVLSVF 658
            T+LS     L +   P   +R   G+            P   A +I +A    F + + F
Sbjct: 3154 TILS--YGSLCDEFTPTEVIRQMYGVNLQAGKVKSFFYPIMTAMTILFAFWLEFFMYTPF 3211

Query: 659  YWLGPNYLAMIIGATTIASASYLSWLRVSQRLHTVNQILVGATVGSAFSAMWFALWHLLV 838
             W+ P ++++++  TT+ S  ++S ++  + L  ++ +L    + +A +  W   ++  +
Sbjct: 3212 TWINPTFVSIVLAVTTLISTVFVSGIK-HKMLFFMSFVLPSVILVTAHNLFWDFSYYESL 3270

Query: 839  REAFASSLWVQIPVVLGSV---VFC-VAFVVYIIQ 931
            +    ++  + +PV +  V   VFC + FV Y ++
Sbjct: 3271 QSIVENTNTMFLPVDMQGVMLTVFCFIVFVTYSVR 3305

>Q9C2M6:DOPP_NEUCR Putative dolichyldiphosphatase - Neurospora crassa|
          Length = 282

 Score = 36.6 bits (83), Expect = 0.25
 Identities = 22/74 (29%), Positives = 35/74 (47%)
 Frame = +2

Query: 662 WLGPNYLAMIIGATTIASASYLSWLRVSQRLHTVNQILVGATVGSAFSAMWFALWHLLVR 841
           W   +     +GA  +A A  ++W R     HT  Q+LVG   G+  +  WF + H +VR
Sbjct: 173 WSFAHRFVASLGALVLAGA--VAWSRTYLGYHTEKQVLVGCGAGTLCAVAWFVVTH-VVR 229

Query: 842 EAFASSLWVQIPVV 883
           ++      +  PVV
Sbjct: 230 QSGLLGQILDFPVV 243



 Score = 33.9 bits (76), Expect = 1.6
 Identities = 22/65 (33%), Positives = 33/65 (50%), Gaps = 4/65 (6%)
 Frame = +2

Query: 467 LWK-HDGEIMWALMGAVANTVLSSVLKKLLNHERPAPALRSDP---GMPSSHAQSIFYAA 634
           +W   + E++    G +A    +  LK+L+  ERPA    +     GMPSSHAQ + + A
Sbjct: 46  IWSTREAEVILMFAGQLACEAANFALKRLIKEERPARIHSTGGKGYGMPSSHAQFVSFWA 105

Query: 635 TFLVL 649
             L L
Sbjct: 106 VALGL 110

>Q810K3:SGPP2_MOUSE Sphingosine-1-phosphate phosphatase 2 - Mus musculus (Mouse)|
          Length = 354

 Score = 35.8 bits (81), Expect = 0.42
 Identities = 37/150 (24%), Positives = 68/150 (45%), Gaps = 8/150 (5%)
 Frame = +2

Query: 488 IMWALMGAVANTVLSSVLKKLLNHERPA--PALR------SDPGMPSSHAQSIFYAATFL 643
           ++W L+       +  V K +L   RP+  P +R      ++ GMPS+HA +    +  L
Sbjct: 78  VIWVLV-----MYIGQVAKDILKWPRPSFPPVVRLEKRIIAEYGMPSTHAMAATAISFTL 132

Query: 644 VLSVFYWLGPNYLAMIIGATTIASASYLSWLRVSQRLHTVNQILVGATVGSAFSAMWFAL 823
           ++S        ++  ++ A   ++   LS  R+   +HTV  IL G  + +   A+ +  
Sbjct: 133 LISTMDRYQYPFILGLMMAVVFSTLVCLS--RLYTGMHTVLDILGGVLITAVLIALTYPA 190

Query: 824 WHLLVREAFASSLWVQIPVVLGSVVFCVAF 913
           W L+     AS L+   PV +  V F + +
Sbjct: 191 WTLIDSLDSASPLF---PVCVIVVPFLLCY 217

>Q9V576:WUN_DROME Putative phosphatidate phosphatase - Drosophila melanogaster (Fruit|
           fly)
          Length = 379

 Score = 34.7 bits (78), Expect = 0.94
 Identities = 21/69 (30%), Positives = 32/69 (46%), Gaps = 3/69 (4%)
 Frame = +2

Query: 599 PSSHAQSIFYAATFLVLSV---FYWLGPNYLAMIIGATTIASASYLSWLRVSQRLHTVNQ 769
           PS H+   F+A  +L L +     W G   L  ++    I  A Y +  RVS   H  + 
Sbjct: 268 PSGHSSFTFFAMVYLALYLQARMTWRGSKLLRHLLQFLFIMVAWYTALSRVSDYKHHWSD 327

Query: 770 ILVGATVGS 796
           +L G+ +GS
Sbjct: 328 VLAGSLIGS 336

>O14495:LPP3_HUMAN Lipid phosphate phosphohydrolase 3 - Homo sapiens (Human)|
          Length = 311

 Score = 34.3 bits (77), Expect = 1.2
 Identities = 22/68 (32%), Positives = 29/68 (42%), Gaps = 3/68 (4%)
 Frame = +2

Query: 602 SSHAQSIFYAATFLVLSV---FYWLGPNYLAMIIGATTIASASYLSWLRVSQRLHTVNQI 772
           S HA    Y   +LVL +   F W G   L  ++  T I  A Y    RVS   H  + +
Sbjct: 197 SGHASFSMYTMLYLVLYLQARFTWRGARLLRPLLQFTLIMMAFYTGLSRVSDHKHHPSDV 256

Query: 773 LVGATVGS 796
           L G   G+
Sbjct: 257 LAGFAQGA 264

>Q3SZE3:LPP3_BOVIN Lipid phosphate phosphohydrolase 3 - Bos taurus (Bovine)|
          Length = 311

 Score = 34.3 bits (77), Expect = 1.2
 Identities = 22/68 (32%), Positives = 29/68 (42%), Gaps = 3/68 (4%)
 Frame = +2

Query: 602 SSHAQSIFYAATFLVLSV---FYWLGPNYLAMIIGATTIASASYLSWLRVSQRLHTVNQI 772
           S HA    Y   +LVL +   F W G   L  ++  T I  A Y    RVS   H  + +
Sbjct: 198 SGHASFSMYTMLYLVLYLQARFTWRGARLLRPLLQFTLIMMAFYTGLSRVSDHKHHPSDV 257

Query: 773 LVGATVGS 796
           L G   G+
Sbjct: 258 LAGFAQGA 265

>Q98VG9:R1AB_FIPV Replicase polyprotein 1ab - Feline coronavirus (strain FIPV|
            WSU-79/1146) (FCoV)
          Length = 6709

 Score = 33.5 bits (75), Expect = 2.1
 Identities = 43/215 (20%), Positives = 88/215 (40%), Gaps = 35/215 (16%)
 Frame = +2

Query: 392  RW--THVEVALNRMSKWLVSASF-------AFAALWKHDGEIMWALMGAVAN-------- 520
            RW  T+  + L   + W  + SF       AF  L    G  +  L+  +          
Sbjct: 3119 RWFVTNTSMTLESYNAWAKTNSFTEIVSTDAFNMLAAKTGYSVEKLLECIVRLNKGFGGR 3178

Query: 521  TVLSSVLKKLLNHERPAPALRSDPG--MPSSHAQSIFYAAT------------FLVLSVF 658
            T+LS     L +   P   +R   G  + S   +SIFY               F + + F
Sbjct: 3179 TILS--YGSLCDEFTPTEVIRQMYGVNLQSGKVKSIFYPMMTAIAILFAFWLEFFMYTPF 3236

Query: 659  YWLGPNYLAMIIGATTIASASYLSWLRVSQRLHTVNQILVGATVGSAFSAMWFALWH--- 829
             W+ P ++++++  TT+ S   ++ ++  + L  ++ ++    + +A + +W   ++   
Sbjct: 3237 TWINPTFVSVVLAITTLVSVLLVAGIK-HKMLFFMSFVMPSVILATAHNVVWDMTYYESL 3295

Query: 830  -LLVREAFASSLWVQIPVVLGSVVFCVAFVVYIIQ 931
             +LV     + L V +  V+ ++   V FV+  I+
Sbjct: 3296 QVLVENVNTTFLPVDMQGVMLALFCVVVFVICTIR 3330

>Q8BIZ6:SNIP1_MOUSE Smad nuclear-interacting protein 1 - Mus musculus (Mouse)|
          Length = 383

 Score = 33.1 bits (74), Expect = 2.7
 Identities = 19/52 (36%), Positives = 27/52 (51%), Gaps = 6/52 (11%)
 Frame = -2

Query: 361 LTGQLLASQHRIPLPVPSRNPNLPGR----PAPDPGHLGH--AHAKPPATEK 224
           LT  ++  +   P PV  R P+ P      PA +PGH GH  + A+ PA +K
Sbjct: 22  LTTVVVKQERLSPEPVAHRRPDAPAASLSPPAAEPGHSGHRGSRARSPAKKK 73

>Q4FZD7:PLK5_MOUSE Serine/threonine-protein kinase PLK5 - Mus musculus (Mouse)|
          Length = 595

 Score = 32.7 bits (73), Expect = 3.6
 Identities = 18/47 (38%), Positives = 24/47 (51%), Gaps = 2/47 (4%)
 Frame = -2

Query: 355 GQLLASQHRIPLPVPSRNPNLPGRPAPDPGHL--GHAHAKPPATEKR 221
           GQLL +Q R P P  S+  + PG    +P H+  G+    P  TE R
Sbjct: 313 GQLLLTQCRPPCPFTSKEASGPGEEGTEPDHMEAGNEERDPLCTEGR 359

>Q9UDY2:ZO2_HUMAN Tight junction protein ZO-2 - Homo sapiens (Human)|
          Length = 1190

 Score = 32.3 bits (72), Expect = 4.7
 Identities = 25/92 (27%), Positives = 44/92 (47%), Gaps = 6/92 (6%)
 Frame = -2

Query: 352  QLLASQHRIPLPVPSRNPNLPGRPA----PDPGHLGHAHAKPPATEKRE*PAFAVRETIQ 185
            Q L       + +  ++P++   P     PDPG   H  ++PP  +K   P+   ++T  
Sbjct: 1098 QELQEAQNARIEIAQKHPDIYAVPIKTHKPDPGTPQHTSSRPPEPQKA--PSRPYQDTRG 1155

Query: 184  AHGLDARPWTWQRQ--EHGCADRQRGSAGESA 95
            ++G DA    +++Q  EH     +RG  G+SA
Sbjct: 1156 SYGSDAEEEEYRQQLSEHS----KRGYYGQSA 1183

>Q28MN2:GLGB_JANSC 1,4-alpha-glucan-branching enzyme - Jannaschia sp. (strain CCS1)|
          Length = 701

 Score = 32.3 bits (72), Expect = 4.7
 Identities = 16/58 (27%), Positives = 26/58 (44%)
 Frame = +2

Query: 440 VSASFAFAALWKHDGEIMWALMGAVANTVLSSVLKKLLNHERPAPALRSDPGMPSSHA 613
           +   FA    W HDG++ W      A+  + ++++ L +  R  PAL     MP   A
Sbjct: 544 MGCEFAQPGEWSHDGDLNWDAASRPAHAGVQALVRDLNHLYRDTPALHVKDCMPDGFA 601

>O00555:CAC1A_HUMAN Voltage-dependent P/Q-type calcium channel subunit alpha-1A - Homo|
           sapiens (Human)
          Length = 2505

 Score = 32.3 bits (72), Expect = 4.7
 Identities = 43/189 (22%), Positives = 66/189 (34%), Gaps = 21/189 (11%)
 Frame = +2

Query: 392 RWTHVEVALNRMSKWLVSASFAFAALWKHDGEIMWALMGAVANTVLSSVLKKLLNHERPA 571
           R   +E  LN   +W+  A     A  + DGE      GA+  T +      LLN E   
Sbjct: 381 RQQQIERELNGYMEWISKAEEVILAEDETDGEQRHPFDGALRRTTIKKSKTDLLNPEEAE 440

Query: 572 PALRSDPGMPSSHAQSI--------------------FYAATFLVLSVFYWLGPNYLAMI 691
             L     + S  A++                     FY    +    FYW   + +A+ 
Sbjct: 441 DQLADIASVGSPFARASIKSAKLENSTFFHKKERRMRFYIRRMVKTQAFYWTVLSLVALN 500

Query: 692 IGATTIASASYLSWLRVSQRLHTVNQILVGATVGSAFSAMWFALWHLLVREAFASSL-WV 868
                I   +   WL  S  L+    I +G  +    S M+  ++ L  R  F SS    
Sbjct: 501 TLCVAIVHYNQPEWL--SDFLYYAEFIFLGLFM----SEMFIKMYGLGTRPYFHSSFNCF 554

Query: 869 QIPVVLGSV 895
              V++GS+
Sbjct: 555 DCGVIIGSI 563

>P28682:OPSB_CHICK Blue-sensitive opsin - Gallus gallus (Chicken)|
          Length = 361

 Score = 32.0 bits (71), Expect = 6.1
 Identities = 34/113 (30%), Positives = 57/113 (50%), Gaps = 5/113 (4%)
 Frame = +2

Query: 596 MPSSHAQS--IFYA-ATFLVLSVFYWLGPNYLAMIIGATTIASASYLSWLRVSQRLHTVN 766
           +P +H  S  +F A A F+ L +   +  N L +   A      S+L+++ V+  L  + 
Sbjct: 33  VPQTHLGSPGLFRAMAAFMFLLIALGVPINTLTIFCTARFRKLRSHLNYILVNLALANLL 92

Query: 767 QILVGATVGS-AFSAMWFALWHLLVR-EAFASSLWVQIPVVLGSVVFCVAFVV 919
            ILVG+T    +FS M+FAL     + E FA++L   + +   +VV    F+V
Sbjct: 93  VILVGSTTACYSFSQMYFALGPTACKIEGFAATLGGMVSLWSLAVVAFERFLV 145

>Q8TWG2:Y1073_METKA UPF0290 protein MK1073 - Methanopyrus kandleri|
          Length = 173

 Score = 31.6 bits (70), Expect = 7.9
 Identities = 27/90 (30%), Positives = 40/90 (44%), Gaps = 1/90 (1%)
 Frame = +2

Query: 470 WKH-DGEIMWALMGAVANTVLSSVLKKLLNHERPAPALRSDPGMPSSHAQSIFYAATFLV 646
           WK  DG I+   +GA+A   + S +K+ +  ER APA       P       F  A  L 
Sbjct: 82  WKAGDGFILG--LGAMAGDAVGSFVKRRIGLERGAPA-------PVLDQLDFFVGAVLLY 132

Query: 647 LSVFYWLGPNYLAMIIGATTIASASYLSWL 736
             V+ W  P ++ + +   T+A    L WL
Sbjct: 133 YLVYGWHPPGWVLVGLAILTLA----LHWL 158

>Q8SHP7:NU5M_TRIRE NADH-ubiquinone oxidoreductase chain 5 - Trichoderma reesei|
           (Hypocrea jecorina)
          Length = 692

 Score = 31.6 bits (70), Expect = 7.9
 Identities = 37/141 (26%), Positives = 59/141 (41%), Gaps = 7/141 (4%)
 Frame = +2

Query: 431 KWLVSASFAFAALWKHDGEIMWALMGAVANTVLSSVLKKLLNHERPAPALRSDPGMPSSH 610
           KWL S SF     ++ D   +  L+  +   V+SS++     H      +  DP     H
Sbjct: 63  KWLDSESFNMVWNFQFDSLTVSMLIPVL---VISSLV-----HFYSIGYMSHDP-----H 109

Query: 611 AQSIF-YAATFLVLSVFYWLGPNYLAMIIGATTIASASYLS----WLRVSQRLHTVNQIL 775
           +Q  F Y + F  + +    G NYL M +G   +   SYL     + R++    +++  L
Sbjct: 110 SQRFFSYLSLFTFMMIILVTGNNYLLMFVGWEGVGVCSYLLVSFWFTRIAANQSSLSAFL 169

Query: 776 VGATVGSAF--SAMWFALWHL 832
               VG  F    M+  LW L
Sbjct: 170 TN-RVGDCFLTIGMFVILWSL 189

>O43688:LPP2_HUMAN Lipid phosphate phosphohydrolase 2 - Homo sapiens (Human)|
          Length = 288

 Score = 31.6 bits (70), Expect = 7.9
 Identities = 23/85 (27%), Positives = 34/85 (40%), Gaps = 3/85 (3%)
 Frame = +2

Query: 566 PAPALRSDPGMPSSHAQSIFYAATFLVLSV---FYWLGPNYLAMIIGATTIASASYLSWL 736
           PA    +     S H+    Y   FL L V     W     L   +    +A A Y+ + 
Sbjct: 154 PADVTEARLSFYSGHSSFGMYCMVFLALYVQARLCWKWARLLRPTVQFFLVAFALYVGYT 213

Query: 737 RVSQRLHTVNQILVGATVGSAFSAM 811
           RVS   H  + +LVG   G+  +A+
Sbjct: 214 RVSDYKHHWSDVLVGLLQGALVAAL 238

>Q9LUJ5:EBP2_ARATH Probable rRNA-processing protein EBP2 homolog - Arabidopsis|
           thaliana (Mouse-ear cress)
          Length = 293

 Score = 31.6 bits (70), Expect = 7.9
 Identities = 28/81 (34%), Positives = 42/81 (51%), Gaps = 3/81 (3%)
 Frame = -2

Query: 247 AKPPATEKRE*PAFAVRETIQAHGLDARPWTWQRQEHGCADRQRGSAGESALMW--GESI 74
           AK   ++K +  A   ++ I++     + W  QRQ+ G +D+    AGE  L +  G+S 
Sbjct: 166 AKEVQSQKMKERAKEKKDNIES----VKKWRKQRQQSGFSDK----AGEPELDFESGKSF 217

Query: 73  SAIGGF*REGISPG-RSGLDG 14
              GG  R G+SPG RSG  G
Sbjct: 218 QRGGGKKRPGVSPGDRSGGKG 238


  Database: uniprot_sprot.fasta.out
    Posted date:  Jul 19, 2007  5:58 PM
  Number of letters in database: 100,686,439
  Number of sequences in database:  274,295
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 274295
Number of Hits to DB: 228,971,729
Number of extensions: 4892442
Number of successful extensions: 16704
Number of sequences better than 10.0: 20
Number of HSP's gapped: 16649
Number of HSP's successfully gapped: 21
Length of query: 447
Length of database: 100,686,439
Length adjustment: 116
Effective length of query: 331
Effective length of database: 68,868,219
Effective search space: 22795380489
Effective search space used: 22795380489
Neighboring words threshold: 12
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)