>K125_TOBAC (O23826) 125 kDa kinesin-related protein|
          Length = 1006

 Score = 64.3 bits (155), Expect = 1e-10
 Identities = 33/49 (67%), Positives = 40/49 (81%), Gaps = 2/49 (4%)
 Frame = -2

Query: 466  PSKGTIESLRAMPIESLMDEFRENHPYES--SKEPKPSLIPRSPLATLN 326
            PSK TIESLRAMP+E L++EFREN+ +ES   KE KPSLIPRSP + +N
Sbjct: 957  PSKVTIESLRAMPMEVLLEEFRENNSFESFQVKEVKPSLIPRSPFSQIN 1005

>K125_ARATH (P82266) Probable 125 kDa kinesin-related protein|
          Length = 1056

 Score = 61.6 bits (148), Expect = 9e-10
 Identities = 31/48 (64%), Positives = 39/48 (81%), Gaps = 2/48 (4%)
 Frame = -2

Query: 466  PSKGTIESLRAMPIESLMDEFRENHPYES--SKEPKPSLIPRSPLATL 329
            P+K TIESLRAMPIE+L++EFREN+ YES  +KE KP  + RSPL+ L
Sbjct: 961  PTKATIESLRAMPIETLVEEFRENNSYESFATKETKPQQLTRSPLSQL 1008

>DLL3_HUMAN (Q9NYJ7) Delta-like protein 3 precursor (Drosophila Delta homolog|
           3)
          Length = 618

 Score = 35.8 bits (81), Expect = 0.056
 Identities = 27/109 (24%), Positives = 39/109 (35%), Gaps = 30/109 (27%)
 Frame = -2

Query: 250 CPCCARFYGM---LALIQCLLHSC*NVSICCGAAE---------------YSCKKFYDEC 125
           C C   FYG+   ++ + C    C N  +C G A+                +C+K  D C
Sbjct: 298 CTCPRGFYGLRCEVSGVTCADGPCFNGGLCVGGADPDSAYICHCPPGFQGSNCEKRVDRC 357

Query: 124 LLHSC*NVSIC------------CGAAEYSCKKFYDECLLHSC*NVSIC 14
            L  C N  +C             G A   C+   D+C   +C N   C
Sbjct: 358 SLQPCRNGGLCLDLGHALRCRCRAGFAGPRCEHDLDDCAGRACANGGTC 406

>DLL3_MOUSE (O88516) Delta-like protein 3 precursor (Drosophila Delta homolog|
           3) (M-Delta-3)
          Length = 592

 Score = 33.9 bits (76), Expect = 0.21
 Identities = 26/109 (23%), Positives = 38/109 (34%), Gaps = 30/109 (27%)
 Frame = -2

Query: 250 CPCCARFYGM---LALIQCLLHSC*NVSICCGAAE---------------YSCKKFYDEC 125
           C C   FYG+   ++ + C    C N  +C G  +                +C+K  D C
Sbjct: 296 CACPRGFYGLRCEVSGVTCADGPCFNGGLCVGGEDPDSAYVCHCPPGFQGSNCEKRVDRC 355

Query: 124 LLHSC*NVSIC------------CGAAEYSCKKFYDECLLHSC*NVSIC 14
            L  C N  +C             G A   C+   D+C   +C N   C
Sbjct: 356 SLQPCQNGGLCLDLGHALRCRCRAGFAGPRCEHDLDDCAGRACANGGTC 404

>DLLA_BRARE (Q6DI48) Delta-like protein A precursor (DeltaA protein)|
          Length = 772

 Score = 33.5 bits (75), Expect = 0.28
 Identities = 27/107 (25%), Positives = 37/107 (34%), Gaps = 28/107 (26%)
 Frame = -2

Query: 250 CPCCARFYGM---LALIQCLLHSC*NVSICC-------------GAAEYSCKKFYDECLL 119
           C C   FYG    L+ + C    C N   C              G A ++C+K  D C  
Sbjct: 354 CTCPPGFYGKNCELSAMTCADGPCFNGGRCADNPDGGYFCQCPTGYAGFNCEKKIDHCSS 413

Query: 118 HSC*NVSICC------------GAAEYSCKKFYDECLLHSC*NVSIC 14
             C N + C             G    +C +  DEC ++ C N   C
Sbjct: 414 SPCSNGARCVDLVNSYLCQCPDGFTGMNCDRAGDECSMYPCQNGGTC 460

>NOTC2_RAT (Q9QW30) Neurogenic locus notch homolog protein 2 precursor (Notch|
           2) [Contains: Notch 2 extracellular truncation; Notch 2
           intracellular domain]
          Length = 2471

 Score = 32.3 bits (72), Expect = 0.62
 Identities = 27/109 (24%), Positives = 40/109 (36%), Gaps = 30/109 (27%)
 Frame = -2

Query: 250 CPCCARFYGMLA---LIQCLLHSC*NVSICCGAAEYS-------------CKKFYDECLL 119
           C C  RF G       + C    C N   C    +++             C++  D+C  
Sbjct: 207 CQCPQRFTGQHCDSPYVPCAPSPCVNGGTCRQTGDFTSECHCLPGFEGSNCERNIDDCPN 266

Query: 118 HSC*NVSICC-GAAEYSCK-----------KFYDECLL--HSC*NVSIC 14
           H C N  +C  G   Y+C+           +  DECLL  ++C N   C
Sbjct: 267 HKCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTC 315



 Score = 28.9 bits (63), Expect = 6.8
 Identities = 28/106 (26%), Positives = 34/106 (32%), Gaps = 27/106 (25%)
 Frame = -2

Query: 250  CPCCARFYGMLA---LIQCLLHSC*NVSICC------------GAAEYSCKKFYDECLLH 116
            C C   F GM     +  CL + C N   C             G     C+   +ECL  
Sbjct: 897  CECPPGFSGMDCEEDINDCLANPCQNGGSCVDKVNTFSCLCLPGFVGDKCQTDMNECLSE 956

Query: 115  SC*NVSIC----------CGAAEYS--CKKFYDECLLHSC*NVSIC 14
             C N   C          C A  +   C+   DEC   SC N   C
Sbjct: 957  PCKNGGTCSDYVNSYTCTCPAGFHGVHCENNIDECTESSCFNGGTC 1002

>SLIT1_RAT (O88279) Slit homolog 1 protein precursor (Slit-1) (Multiple|
            epidermal growth factor-like domains 4)
          Length = 1531

 Score = 32.0 bits (71), Expect = 0.80
 Identities = 27/108 (25%), Positives = 41/108 (37%), Gaps = 29/108 (26%)
 Frame = -2

Query: 250  CPCCARFYGMLALIQ---CLLHSC*NVSICC-GAAEYSCK-----------KFYDECL-- 122
            C C + F G+   +    C+ H C N  +C  G   Y+C+           +  D C   
Sbjct: 991  CSCPSGFEGLTCGMNTDDCVKHDCVNGGVCVDGIGNYTCQCPLQYTGRACEQLVDFCSPD 1050

Query: 121  LHSC*NVSICCGAAEY------------SCKKFYDECLLHSC*NVSIC 14
            L+ C + + C G  E             +C K  D+C  H C N + C
Sbjct: 1051 LNPCQHEAQCVGTPEGPRCECVPGYTGDNCSKNQDDCKDHQCQNGAQC 1098

>NOTCH_DROME (P07207) Neurogenic locus Notch protein precursor|
          Length = 2703

 Score = 31.2 bits (69), Expect = 1.4
 Identities = 12/30 (40%), Positives = 20/30 (66%), Gaps = 1/30 (3%)
 Frame = -2

Query: 151 SCKKFYDECLLHSC*NVSICC-GAAEYSCK 65
           +C++ YD+CL H C N   C  G ++Y+C+
Sbjct: 289 NCEQNYDDCLGHLCQNGGTCIDGISDYTCR 318



 Score = 28.5 bits (62), Expect = 8.9
 Identities = 18/57 (31%), Positives = 23/57 (40%), Gaps = 12/57 (21%)
 Frame = -2

Query: 148 CKKFYDECLLHSC*NVSICCGAAE-YSC---KKFY--------DECLLHSC*NVSIC 14
           C+K  DEC+   C N  +C      Y C   + FY        DEC  + C N   C
Sbjct: 712 CEKNVDECISSPCANNGVCIDQVNGYKCECPRGFYDAHCLSDVDECASNPCVNEGRC 768

>DLL3_RAT (O88671) Delta-like protein 3 precursor (Drosophila Delta homolog|
           3)
          Length = 589

 Score = 31.2 bits (69), Expect = 1.4
 Identities = 25/109 (22%), Positives = 37/109 (33%), Gaps = 30/109 (27%)
 Frame = -2

Query: 250 CPCCARFYGM---LALIQCLLHSC*NVSICCGAAE---------------YSCKKFYDEC 125
           C C   FYG    ++ + C    C N  +C G  +                +C++  D C
Sbjct: 300 CACPRGFYGPRCEVSGVTCADGPCFNGGLCVGGEDPDSAYVCHCPPAFQGSNCERRVDRC 359

Query: 124 LLHSC*NVSIC------------CGAAEYSCKKFYDECLLHSC*NVSIC 14
            L  C N  +C             G A   C+   D+C   +C N   C
Sbjct: 360 SLQPCQNGGLCLDLGHALRCRCRAGFAGPRCEHDLDDCAGRACANGGTC 408

>PALA_SCHPO (Q09807) pH-response regulator protein palA/rim20|
          Length = 701

 Score = 30.4 bits (67), Expect = 2.3
 Identities = 13/53 (24%), Positives = 35/53 (66%), Gaps = 6/53 (11%)
 Frame = +1

Query: 67  YKNIRRLHNKLIHSSRNAKDTRHRIFYKNIRRLHNKL------IHSSKNAKDT 207
           Y++  +  +++I+S +++++ + + FY ++ +LH ++      + +S+NAKDT
Sbjct: 439 YRHCCQALDEIINSVKSSQNMKEKGFYSDVIKLHEEVSLLKVNVENSQNAKDT 491



 Score = 29.3 bits (64), Expect = 5.2
 Identities = 12/45 (26%), Positives = 31/45 (68%), Gaps = 6/45 (13%)
 Frame = +1

Query: 13  NKLIHSSRNAKDTRHRIFYKNIRRLHNKL------IHSSRNAKDT 129
           +++I+S +++++ + + FY ++ +LH ++      + +S+NAKDT
Sbjct: 447 DEIINSVKSSQNMKEKGFYSDVIKLHEEVSLLKVNVENSQNAKDT 491

>CUBN_CANFA (Q9TU53) Cubilin precursor|
          Length = 3620

 Score = 30.4 bits (67), Expect = 2.3
 Identities = 25/87 (28%), Positives = 32/87 (36%), Gaps = 11/87 (12%)
 Frame = -2

Query: 241 CARFYGMLALIQCLLHSC*NVSICCGAAEYSCKKFYDECLLHSC*NVS--------IC-- 92
           C+   G L L  CL     N     G     C +  D CL H C N          +C  
Sbjct: 363 CSSVLGSLPLCTCLPGYTGN-----GYGPNGCAQLSDTCLSHPCLNGQCIETVSGYLCKC 417

Query: 91  -CGAAEYSCKKFYDECLLHSC*NVSIC 14
             G A  +C +  +ECL + C N   C
Sbjct: 418 ESGWAGINCTENINECLSNPCFNGGTC 444

>NOTC2_HUMAN (Q04721) Neurogenic locus notch homolog protein 2 precursor (Notch|
           2) (hN2) [Contains: Notch 2 extracellular truncation;
           Notch 2 intracellular domain]
          Length = 2471

 Score = 30.0 bits (66), Expect = 3.1
 Identities = 26/109 (23%), Positives = 39/109 (35%), Gaps = 30/109 (27%)
 Frame = -2

Query: 250 CPCCARFYGMLA---LIQCLLHSC*NVSICCGAAEYS-------------CKKFYDECLL 119
           C C   F G       + C    C N   C    +++             C++  D+C  
Sbjct: 207 CQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCPN 266

Query: 118 HSC*NVSICC-GAAEYSCK-----------KFYDECLL--HSC*NVSIC 14
           H C N  +C  G   Y+C+           +  DECLL  ++C N   C
Sbjct: 267 HRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTC 315

>NOTC1_HUMAN (P46531) Neurogenic locus notch homolog protein 1 precursor (Notch 1)|
            (hN1) (Translocation-associated notch protein TAN-1)
            [Contains: Notch 1 extracellular truncation; Notch 1
            intracellular domain]
          Length = 2556

 Score = 30.0 bits (66), Expect = 3.1
 Identities = 19/57 (33%), Positives = 22/57 (38%), Gaps = 12/57 (21%)
 Frame = -2

Query: 148  CKKFYDECLLHSC*NVSICCG-AAEYSCK-----------KFYDECLLHSC*NVSIC 14
            C+   DEC    C N + C      YSCK           +  DECL H C N   C
Sbjct: 1143 CEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQNGGTC 1199

>NOTCH_XENLA (P21783) Neurogenic locus notch protein homolog precursor (XOTCH|
            protein)
          Length = 2524

 Score = 29.6 bits (65), Expect = 4.0
 Identities = 20/72 (27%), Positives = 28/72 (38%), Gaps = 15/72 (20%)
 Frame = -2

Query: 184  NVSICCGAAEYS---CKKFYDECLLHSC*NVSIC------------CGAAEYSCKKFYDE 50
            N   C   A Y+   C++  DEC  + C N + C             G    +C +  +E
Sbjct: 1126 NTHFCRCQAGYTGSYCEEQVDECSPNPCQNGATCTDYLGGYSCECVAGYHGVNCSEEINE 1185

Query: 49   CLLHSC*NVSIC 14
            CL H C N   C
Sbjct: 1186 CLSHPCQNGGTC 1197

>NOTC2_MOUSE (O35516) Neurogenic locus notch homolog protein 2 precursor (Notch|
           2) (Motch B) [Contains: Notch 2 extracellular
           truncation; Notch 2 intracellular domain]
          Length = 2470

 Score = 29.6 bits (65), Expect = 4.0
 Identities = 18/60 (30%), Positives = 28/60 (46%), Gaps = 14/60 (23%)
 Frame = -2

Query: 151 SCKKFYDECLLHSC*NVSICC-GAAEYSCK-----------KFYDECLL--HSC*NVSIC 14
           +C++  D+C  H C N  +C  G   Y+C+           +  DECLL  ++C N   C
Sbjct: 254 TCERNIDDCPNHKCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTC 313

>Y244_BUCAP (Q8K9R6) UPF0125 protein BUsg244|
          Length = 95

 Score = 29.3 bits (64), Expect = 5.2
 Identities = 12/31 (38%), Positives = 19/31 (61%)
 Frame = +1

Query: 64  FYKNIRRLHNKLIHSSRNAKDTRHRIFYKNI 156
           FYKN   ++NKL+H + N K+      Y+N+
Sbjct: 47  FYKNNVGIYNKLVHLNENVKNGDRIEIYRNL 77

>GSTP_DIRIM (P46426) Glutathione S-transferase (EC 2.5.1.18) (GST class-pi)|
          Length = 208

 Score = 29.3 bits (64), Expect = 5.2
 Identities = 15/45 (33%), Positives = 24/45 (53%)
 Frame = +1

Query: 22  IHSSRNAKDTRHRIFYKNIRRLHNKLIHSSRNAKDTRHRIFYKNI 156
           ++   NA+ +   +FY+ IR LH+K       A +T+   F KNI
Sbjct: 76  LNGENNAETSYVDMFYEGIRDLHSKYTRMIYEAYETQKDPFIKNI 120

>NOTC1_BRARE (P46530) Neurogenic locus notch homolog protein 1 precursor|
          Length = 2437

 Score = 28.9 bits (63), Expect = 6.8
 Identities = 26/99 (26%), Positives = 37/99 (37%), Gaps = 20/99 (20%)
 Frame = -2

Query: 250  CPCCARFYGMLALIQCLLHS-----C*NVSICCGAAEYS---CKKFYDECLLHSC*NVSI 95
            C   AR  G+   + C  H+       N  +C   A Y+   C++  DEC  + C N + 
Sbjct: 1099 CEVAARQQGVSVAVLCR-HAGQCVDAGNTHLCRCQAGYTGSYCQEQVDECQPNPCQNGAT 1157

Query: 94   CC------------GAAEYSCKKFYDECLLHSC*NVSIC 14
            C             G    +C K  +ECL   C N   C
Sbjct: 1158 CTDYLGGYSCECVPGYHGMNCSKEINECLSQPCQNGGTC 1196

>HELS_METJA (Q58524) Putative ski2-type helicase (EC 3.6.1.-) [Contains:|
           Endonuclease PI-MjaHel (EC 3.1.-.-) (Mja Hel intein)
           (Mja Pep3 intein)]
          Length = 1195

 Score = 28.9 bits (63), Expect = 6.8
 Identities = 14/40 (35%), Positives = 22/40 (55%)
 Frame = +1

Query: 85  LHNKLIHSSRNAKDTRHRIFYKNIRRLHNKLIHSSKNAKD 204
           LH K     R +K   H I+ K +R++ NKL   +K+ K+
Sbjct: 490 LHKKYFLKCRISKGVAHYIYSKKLRKIFNKLNMLTKDNKN 529

>MT1X_HUMAN (P80297) Metallothionein-1X (MT-1X) (Metallothionein-IX) (MT-IX)|
          Length = 61

 Score = 28.5 bits (62), Expect = 8.9
 Identities = 18/61 (29%), Positives = 20/61 (32%)
 Frame = -2

Query: 193 SC*NVSICCGAAEYSCKKFYDECLLHSC*NVSICCGAAEYSCKKFYDECLLHSC*NVSIC 14
           SC  V  C  A    CK    EC   SC     CC      C K    C+     +   C
Sbjct: 6   SCSPVGSCACAGSCKCK----ECKCTSC--KKSCCSCCPVGCAKCAQGCICKGTSDKCSC 59

Query: 13  C 11
           C
Sbjct: 60  C 60

>HIS8_BLOFL (Q7VQW9) Histidinol-phosphate aminotransferase (EC 2.6.1.9)|
           (Imidazole acetol-phosphate transaminase)
          Length = 356

 Score = 28.5 bits (62), Expect = 8.9
 Identities = 14/52 (26%), Positives = 26/52 (50%)
 Frame = -3

Query: 201 FCILARMYQFVVEPPNILVKNSMTSVFCIPARMYQFVVEPPNILVKNSMTSV 46
           FC  A + Q + E PN+++  +++  F +      F +  P I+  N +T V
Sbjct: 187 FCRHASLIQLLTEYPNLIILRTLSKAFALAGLRCGFTLANPKII--NLLTKV 236

>PRP4B_HUMAN (Q13523) Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1)|
           (PRP4 pre-mRNA-processing factor 4 homolog) (PRP4
           kinase)
          Length = 1007

 Score = 28.5 bits (62), Expect = 8.9
 Identities = 15/49 (30%), Positives = 25/49 (51%)
 Frame = +1

Query: 43  KDTRHRIFYKNIRRLHNKLIHSSRNAKDTRHRIFYKNIRRLHNKLIHSS 189
           K +RH+      R  H K  HSS   KD +H+  +K+ +    ++I +S
Sbjct: 39  KHSRHKKKKHKHRSKHKKHKHSSEEDKDKKHKHKHKHKKHKRKEVIDAS 87

>CRUM1_MOUSE (Q8VHS2) Crumbs homolog 1 precursor|
          Length = 1405

 Score = 28.5 bits (62), Expect = 8.9
 Identities = 17/46 (36%), Positives = 22/46 (47%), Gaps = 2/46 (4%)
 Frame = -2

Query: 181 VSICC-GAAEYSCKKFYDECLLHSC*NVSICCG-AAEYSCKKFYDE 50
           V IC  G     C++  DECLLH C N   C      Y+C   +D+
Sbjct: 381 VCICQPGFTGIHCEEDVDECLLHPCLNGGTCENLPGNYACHCPFDD 426

>SLIT1_MOUSE (Q80TR4) Slit homolog 1 protein precursor (Slit-1)|
          Length = 1531

 Score = 28.5 bits (62), Expect = 8.9
 Identities = 24/108 (22%), Positives = 41/108 (37%), Gaps = 29/108 (26%)
 Frame = -2

Query: 250  CPCCARFYGMLALIQ---CLLHSC*NVSICC-GAAEYSCK-----------KFYDECL-- 122
            C C + F G    +    C+ H+C N  +C  G   Y+C+           +  D C   
Sbjct: 991  CSCPSGFEGPTCGVDTDDCVKHACVNGGVCVDGVGNYTCQCPLQYTGRACEQLVDFCSPD 1050

Query: 121  LHSC*NVSICCGAAEY------------SCKKFYDECLLHSC*NVSIC 14
            ++ C + + C G  +             +C +  D+C  H C N + C
Sbjct: 1051 MNPCQHEAQCVGTPDGPRCECMLGYTGDNCSENQDDCKDHKCQNGAQC 1098

>EAA3_CAEEL (Q21353) Putative sodium-dependent excitatory amino acid|
           transporter glt-3
          Length = 532

 Score = 28.5 bits (62), Expect = 8.9
 Identities = 16/37 (43%), Positives = 19/37 (51%), Gaps = 11/37 (29%)
 Frame = +2

Query: 344 RARDERRLG-----------FLARFIGMVLTELIHQG 421
           RARD RR+G           FLA F G++L   IH G
Sbjct: 70  RARDARRIGIVTIIYYMITTFLATFTGIILVSSIHPG 106

>DL_DROME (P10041) Neurogenic locus protein delta precursor|
          Length = 833

 Score = 28.5 bits (62), Expect = 8.9
 Identities = 26/103 (25%), Positives = 32/103 (31%), Gaps = 24/103 (23%)
 Frame = -2

Query: 250 CPCCARFYGM---LALIQCLLHSC*NVSIC---------CGAAEYSCKKFYDECLLHSC* 107
           C C   + G    L L  C  + C N   C          G +   C+   D+CL H C 
Sbjct: 404 CECPIGYSGPNCDLQLDNCSPNPCINGGSCQPSGKCICPAGFSGTRCETNIDDCLGHQCE 463

Query: 106 NVSICC------------GAAEYSCKKFYDECLLHSC*NVSIC 14
           N   C             G     C    D CL+  C N   C
Sbjct: 464 NGGTCIDMVNQYRCQCVPGFHGTHCSSKVDLCLIRPCANGGTC 506


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 66,745,971
Number of Sequences: 219361
Number of extensions: 1319778
Number of successful extensions: 3680
Number of sequences better than 10.0: 26
Number of HSP's better than 10.0 without gapping: 2897
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3625
length of database: 80,573,946
effective HSP length: 103
effective length of database: 57,979,763
effective search space used: 3014947676
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)