>VPP4_HUMAN (Q9HBG4) Vacuolar proton translocating ATPase 116 kDa subunit a|
           isoform 4 (V-ATPase 116-kDa isoform a4) (Vacuolar proton
           translocating ATPase 116 kDa subunit a kidney isoform)
          Length = 840

 Score = 81.3 bits (199), Expect = 1e-15
 Identities = 36/42 (85%), Positives = 39/42 (92%)
 Frame = -3

Query: 486 TVGVLLVMETLSAFLHALRLHWVEFQNKFYEGDGYKFAPFSF 361
           TV +LL+ME LSAFLHALRLHWVEFQNKFY GDGYKF+PFSF
Sbjct: 789 TVAILLIMEGLSAFLHALRLHWVEFQNKFYVGDGYKFSPFSF 830

>VPP1_BOVIN (Q29466) Vacuolar proton translocating ATPase 116 kDa subunit a|
           isoform 1 (V-ATPase 116-kDa isoform a1) (Clathrin-coated
           vesicle/synaptic vesicle proton pump 116 kDa subunit)
           (Vacuolar proton pump subunit 1) (Vacuolar adenosine
           triphosphatase
          Length = 838

 Score = 78.6 bits (192), Expect = 8e-15
 Identities = 36/47 (76%), Positives = 39/47 (82%)
 Frame = -3

Query: 486 TVGVLLVMETLSAFLHALRLHWVEFQNKFYEGDGYKFAPFSFALISE 346
           TV +LL+ME LSAFLHALRLHWVEFQNKFY G G+KF PFSF  I E
Sbjct: 787 TVAILLIMEGLSAFLHALRLHWVEFQNKFYSGTGFKFLPFSFEHIRE 833

>VPP4_MOUSE (Q920R6) Vacuolar proton translocating ATPase 116 kDa subunit a|
           isoform 4 (V-ATPase 116-kDa isoform a4) (Vacuolar proton
           translocating ATPase 116 kDa subunit a kidney isoform)
          Length = 833

 Score = 78.6 bits (192), Expect = 8e-15
 Identities = 37/47 (78%), Positives = 40/47 (85%)
 Frame = -3

Query: 486 TVGVLLVMETLSAFLHALRLHWVEFQNKFYEGDGYKFAPFSFALISE 346
           TV +LLVME LSAFLHALRLHWVEFQNKFYEG G KF+PFSF  + E
Sbjct: 782 TVAILLVMEGLSAFLHALRLHWVEFQNKFYEGAGSKFSPFSFKHVLE 828

>VPP1_PONPY (Q5R422) Vacuolar proton translocating ATPase 116 kDa subunit a|
           isoform 1 (V-ATPase 116-kDa isoform a1)
          Length = 837

 Score = 78.6 bits (192), Expect = 8e-15
 Identities = 36/47 (76%), Positives = 39/47 (82%)
 Frame = -3

Query: 486 TVGVLLVMETLSAFLHALRLHWVEFQNKFYEGDGYKFAPFSFALISE 346
           TV +LL+ME LSAFLHALRLHWVEFQNKFY G G+KF PFSF  I E
Sbjct: 786 TVAILLIMEGLSAFLHALRLHWVEFQNKFYSGTGFKFLPFSFEHIRE 832

>VPP1_HUMAN (Q93050) Vacuolar proton translocating ATPase 116 kDa subunit a|
           isoform 1 (V-ATPase 116-kDa isoform a1) (Clathrin-coated
           vesicle/synaptic vesicle proton pump 116 kDa subunit)
           (Vacuolar proton pump subunit 1) (Vacuolar adenosine
           triphosphatase
          Length = 837

 Score = 78.6 bits (192), Expect = 8e-15
 Identities = 36/47 (76%), Positives = 39/47 (82%)
 Frame = -3

Query: 486 TVGVLLVMETLSAFLHALRLHWVEFQNKFYEGDGYKFAPFSFALISE 346
           TV +LL+ME LSAFLHALRLHWVEFQNKFY G G+KF PFSF  I E
Sbjct: 786 TVAILLIMEGLSAFLHALRLHWVEFQNKFYSGTGFKFLPFSFEHIRE 832

>VPP1_MOUSE (Q9Z1G4) Vacuolar proton translocating ATPase 116 kDa subunit a|
           isoform 1 (V-ATPase 116-kDa isoform a1) (Clathrin-coated
           vesicle/synaptic vesicle proton pump 116 kDa subunit)
           (Vacuolar proton pump subunit 1) (Vacuolar adenosine
           triphosphatase
          Length = 839

 Score = 78.2 bits (191), Expect = 1e-14
 Identities = 36/47 (76%), Positives = 39/47 (82%)
 Frame = -3

Query: 486 TVGVLLVMETLSAFLHALRLHWVEFQNKFYEGDGYKFAPFSFALISE 346
           TV +LL+ME LSAFLHALRLHWVEFQNKFY G G+KF PFSF  I E
Sbjct: 788 TVAILLIMEGLSAFLHALRLHWVEFQNKFYTGTGFKFLPFSFEHIRE 834

>VPP1_RAT (P25286) Vacuolar proton translocating ATPase 116 kDa subunit a|
           isoform 1 (V-ATPase 116-kDa isoform a1) (Clathrin-coated
           vesicle/synaptic vesicle proton pump 116 kDa subunit)
           (Vacuolar proton pump subunit 1) (Vacuolar adenosine
           triphosphatase su
          Length = 838

 Score = 78.2 bits (191), Expect = 1e-14
 Identities = 36/47 (76%), Positives = 39/47 (82%)
 Frame = -3

Query: 486 TVGVLLVMETLSAFLHALRLHWVEFQNKFYEGDGYKFAPFSFALISE 346
           TV +LL+ME LSAFLHALRLHWVEFQNKFY G G+KF PFSF  I E
Sbjct: 787 TVAILLIMEGLSAFLHALRLHWVEFQNKFYTGTGFKFLPFSFEHIRE 833

>VPP3_HUMAN (Q13488) Vacuolar proton translocating ATPase 116 kDa subunit a|
           isoform 3 (V-ATPase 116-kDa isoform a3) (Osteoclastic
           proton pump 116 kDa subunit) (OC-116 kDa) (OC116)
           (T-cell immune regulator 1) (T cell immune response
           cDNA7 protein) (TIRC7)
          Length = 830

 Score = 77.8 bits (190), Expect = 1e-14
 Identities = 35/43 (81%), Positives = 38/43 (88%)
 Frame = -3

Query: 486 TVGVLLVMETLSAFLHALRLHWVEFQNKFYEGDGYKFAPFSFA 358
           TV +LLVME LSAFLHALRLHWVEFQNKFY G GYK +PF+FA
Sbjct: 784 TVAILLVMEGLSAFLHALRLHWVEFQNKFYSGTGYKLSPFTFA 826

>VPP2_MOUSE (P15920) Vacuolar proton translocating ATPase 116 kDa subunit a|
           isoform 2 (V-ATPase 116-kDa isoform a2) (Immune
           suppressor factor J6B7)
          Length = 856

 Score = 76.6 bits (187), Expect = 3e-14
 Identities = 35/46 (76%), Positives = 40/46 (86%)
 Frame = -3

Query: 486 TVGVLLVMETLSAFLHALRLHWVEFQNKFYEGDGYKFAPFSFALIS 349
           T+ +LLVME LSAFLHA+RLHWVEFQNKFY G G KF PFSF+L+S
Sbjct: 801 TIFILLVMEGLSAFLHAIRLHWVEFQNKFYVGAGTKFVPFSFSLLS 846

>VPP2_HUMAN (Q9Y487) Vacuolar proton translocating ATPase 116 kDa subunit a|
           isoform 2 (V-ATPase 116-kDa isoform a2) (TJ6)
          Length = 856

 Score = 76.3 bits (186), Expect = 4e-14
 Identities = 34/46 (73%), Positives = 40/46 (86%)
 Frame = -3

Query: 486 TVGVLLVMETLSAFLHALRLHWVEFQNKFYEGDGYKFAPFSFALIS 349
           T+ +LL+ME LSAFLHA+RLHWVEFQNKFY G G KF PFSF+L+S
Sbjct: 801 TIFILLIMEGLSAFLHAIRLHWVEFQNKFYVGAGTKFVPFSFSLLS 846

>VPP2_BOVIN (O97681) Vacuolar proton translocating ATPase 116 kDa subunit A|
           isoform 2 (V-ATPase 116-kDa isoform a2)
          Length = 854

 Score = 75.5 bits (184), Expect = 7e-14
 Identities = 34/46 (73%), Positives = 39/46 (84%)
 Frame = -3

Query: 486 TVGVLLVMETLSAFLHALRLHWVEFQNKFYEGDGYKFAPFSFALIS 349
           T+ +LL+ME LSAFLHA+RLHWVEFQNKFY G G KF PFSF L+S
Sbjct: 801 TIFILLIMEGLSAFLHAIRLHWVEFQNKFYVGAGTKFVPFSFRLLS 846

>VPP1_CAEEL (P30628) Probable vacuolar proton translocating ATPase 116 kDa|
            subunit a (Uncoordinated protein 32)
          Length = 905

 Score = 74.3 bits (181), Expect = 2e-13
 Identities = 36/55 (65%), Positives = 43/55 (78%)
 Frame = -3

Query: 486  TVGVLLVMETLSAFLHALRLHWVEFQNKFYEGDGYKFAPFSFALISEDEE*ARPN 322
            +V +L++ME LSAFLHALRLHWVEFQ+KFY G GY+FAPFSF  I  +E  A  N
Sbjct: 850  SVFILVLMEGLSAFLHALRLHWVEFQSKFYGGLGYEFAPFSFEKILAEEREAEEN 904

>STV1_YEAST (P37296) Vacuolar ATP synthase subunit a, Golgi isoform (EC|
           3.6.3.14) (V-ATPase 101 kDa subunit) (V-ATPase subunit
           AC115) (Similar to VPH1 protein 1)
          Length = 890

 Score = 63.5 bits (153), Expect = 3e-10
 Identities = 29/47 (61%), Positives = 35/47 (74%)
 Frame = -3

Query: 486 TVGVLLVMETLSAFLHALRLHWVEFQNKFYEGDGYKFAPFSFALISE 346
           TV +L+ ME  SA LHALRLHWVE  +KF+EG+GY + PFSF  I E
Sbjct: 844 TVCILVFMEGTSAMLHALRLHWVEAMSKFFEGEGYAYEPFSFRAIIE 890

>VPH1_SCHPO (O13742) Probable vacuolar ATP synthase 91 kDa subunit (Vacuolar|
           ATPase 91 kDa subunit)
          Length = 805

 Score = 58.5 bits (140), Expect = 9e-09
 Identities = 26/47 (55%), Positives = 34/47 (72%)
 Frame = -3

Query: 486 TVGVLLVMETLSAFLHALRLHWVEFQNKFYEGDGYKFAPFSFALISE 346
           T  VL+ ME  SA LH+LRLHWVE  +K +EG+GY F PF+F + +E
Sbjct: 759 TCVVLVAMEGTSAMLHSLRLHWVEGMSKHFEGEGYAFTPFTFKVTAE 805

>VPH1_YEAST (P32563) Vacuolar ATP synthase subunit a, vacuolar isoform (EC|
           3.6.3.14) (V-ATPase a subunit) (Vacuolar proton pump a
           subunit) (V-ATPase 95 kDa subunit) (Vacuolar pH protein
           1)
          Length = 839

 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 23/42 (54%), Positives = 31/42 (73%)
 Frame = -3

Query: 486 TVGVLLVMETLSAFLHALRLHWVEFQNKFYEGDGYKFAPFSF 361
           T  VL++ME  SA LH+LRLHWVE  +KF+ G+G  + PF+F
Sbjct: 780 TCAVLVLMEGTSAMLHSLRLHWVESMSKFFVGEGLPYEPFAF 821

>VATI_METJA (Q57675) V-type ATP synthase subunit I (EC 3.6.3.14) (V-type ATPase|
           subunit I)
          Length = 695

 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 22/34 (64%), Positives = 28/34 (82%)
 Frame = -3

Query: 468 VMETLSAFLHALRLHWVEFQNKFYEGDGYKFAPF 367
           VM  L AF+H+LRLH+VEF ++FYEG G KF+PF
Sbjct: 653 VMNGLGAFIHSLRLHYVEFFSQFYEGGGKKFSPF 686

>VPH1_NEUCR (Q01290) Vacuolar ATP synthase 98 kDa subunit (Vacuolar ATPase 98|
           kDa subunit)
          Length = 856

 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 25/50 (50%), Positives = 34/50 (68%)
 Frame = -3

Query: 486 TVGVLLVMETLSAFLHALRLHWVEFQNKFYEGDGYKFAPFSFALISEDEE 337
           +V +L++ME +SA LH+LRL WVE  +KF E  G+ F PFSF    E+ E
Sbjct: 800 SVIILIIMEGVSAMLHSLRLAWVESFSKFAEFGGWPFTPFSFKQQLEESE 849

>VATI_PYRHO (O57721) V-type ATP synthase subunit I (EC 3.6.3.14) (V-type ATPase|
           subunit I)
          Length = 659

 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 20/34 (58%), Positives = 25/34 (73%)
 Frame = -3

Query: 465 METLSAFLHALRLHWVEFQNKFYEGDGYKFAPFS 364
           +  L AF+HALRLH+VEF   FY G+G KF PF+
Sbjct: 614 INALGAFVHALRLHYVEFFGTFYSGEGRKFEPFA 647

>VATI_PYRAB (Q9UXU2) V-type ATP synthase subunit I (EC 3.6.3.14) (V-type ATPase|
           subunit I)
          Length = 659

 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 20/34 (58%), Positives = 25/34 (73%)
 Frame = -3

Query: 465 METLSAFLHALRLHWVEFQNKFYEGDGYKFAPFS 364
           +  L AF+HALRLH+VEF   FY G+G KF PF+
Sbjct: 614 INALGAFVHALRLHYVEFFGTFYSGEGRKFEPFA 647

>VATI_PYRKO (Q5JDS2) V-type ATP synthase subunit I (EC 3.6.3.14) (V-type ATPase|
           subunit I)
          Length = 663

 Score = 45.8 bits (107), Expect = 6e-05
 Identities = 19/33 (57%), Positives = 24/33 (72%)
 Frame = -3

Query: 465 METLSAFLHALRLHWVEFQNKFYEGDGYKFAPF 367
           +  L AF+HALRLH+VEF   FY G+G +F PF
Sbjct: 618 INALGAFVHALRLHYVEFFGTFYSGEGKRFEPF 650

>VATI_METMA (O59659) V-type ATP synthase subunit I (EC 3.6.3.14) (V-type ATPase|
           subunit I)
          Length = 649

 Score = 45.4 bits (106), Expect = 8e-05
 Identities = 20/40 (50%), Positives = 27/40 (67%)
 Frame = -3

Query: 480 GVLLVMETLSAFLHALRLHWVEFQNKFYEGDGYKFAPFSF 361
           G+  ++  ++  LHALRL +VEF  KFYEG G KF PF +
Sbjct: 603 GLNTILSIIAPGLHALRLQYVEFFGKFYEGGGRKFNPFGY 642

>VATI_HALSA (Q9HND8) V-type ATP synthase subunit I (EC 3.6.3.14) (V-type ATPase|
           subunit I)
          Length = 722

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 21/39 (53%), Positives = 27/39 (69%)
 Frame = -3

Query: 477 VLLVMETLSAFLHALRLHWVEFQNKFYEGDGYKFAPFSF 361
           ++L +   SA L ALRL +VEF NKFYEG G K+ PF +
Sbjct: 676 LVLALGVTSAGLQALRLEYVEFFNKFYEGGGEKYNPFGY 714

>NTPI_ENTHR (P43439) V-type sodium ATP synthase subunit I (EC 3.6.3.15)|
           (Na(+)-translocating ATPase subunit I)
          Length = 664

 Score = 38.9 bits (89), Expect = 0.007
 Identities = 20/48 (41%), Positives = 27/48 (56%), Gaps = 9/48 (18%)
 Frame = -3

Query: 486 TVGVLLV---------METLSAFLHALRLHWVEFQNKFYEGDGYKFAP 370
           +VG+LL+         +  LSA++H  RL +VEF  KFY G G  F P
Sbjct: 602 SVGILLIIVLQALNMFLTLLSAYVHGARLQYVEFFGKFYTGGGRSFKP 649

>VATI_AERPE (Q9YEA0) V-type ATP synthase subunit I (EC 3.6.3.14) (V-type ATPase|
           subunit I)
          Length = 686

 Score = 38.1 bits (87), Expect = 0.013
 Identities = 17/32 (53%), Positives = 21/32 (65%)
 Frame = -3

Query: 465 METLSAFLHALRLHWVEFQNKFYEGDGYKFAP 370
           ME L AF HA RLH+ E+ +KFY G G  + P
Sbjct: 640 MEGLLAFAHASRLHFYEWFSKFYSGTGVPYTP 671

>VATI_ARCFU (O29106) V-type ATP synthase subunit I (EC 3.6.3.14) (V-type ATPase|
           subunit I)
          Length = 676

 Score = 38.1 bits (87), Expect = 0.013
 Identities = 17/35 (48%), Positives = 23/35 (65%)
 Frame = -3

Query: 471 LVMETLSAFLHALRLHWVEFQNKFYEGDGYKFAPF 367
           L++  L   L +LRLH+VEF  KF+EG G  + PF
Sbjct: 633 LILGILDPGLQSLRLHYVEFFTKFFEGGGRLYEPF 667

>VATI_SULSO (Q9UWW3) V-type ATP synthase subunit I (EC 3.6.3.14) (V-type ATPase|
           subunit I)
          Length = 701

 Score = 37.7 bits (86), Expect = 0.017
 Identities = 20/40 (50%), Positives = 25/40 (62%), Gaps = 2/40 (5%)
 Frame = -3

Query: 483 VGVLLV--METLSAFLHALRLHWVEFQNKFYEGDGYKFAP 370
           +G LL   +E L  F+  LRLH+ E  +KFYEG G KF P
Sbjct: 654 IGNLLAIGLEGLVVFIQDLRLHFYEMFSKFYEGRGRKFEP 693

>VATI_METTH (O27041) V-type ATP synthase subunit I (EC 3.6.3.14) (V-type ATPase|
           subunit I)
          Length = 658

 Score = 35.8 bits (81), Expect = 0.063
 Identities = 16/32 (50%), Positives = 23/32 (71%)
 Frame = -3

Query: 462 ETLSAFLHALRLHWVEFQNKFYEGDGYKFAPF 367
           ++L AF+++LRLH+VEF  +FY G   KF  F
Sbjct: 616 QSLGAFINSLRLHYVEFFAQFYMGGKNKFNAF 647

>VATI_THEAC (Q9HM61) V-type ATP synthase subunit I (EC 3.6.3.14) (V-type ATPase|
           subunit I)
          Length = 637

 Score = 32.3 bits (72), Expect = 0.70
 Identities = 14/35 (40%), Positives = 20/35 (57%)
 Frame = -3

Query: 471 LVMETLSAFLHALRLHWVEFQNKFYEGDGYKFAPF 367
           L++      +   RL +VEF +KFY G+G  F PF
Sbjct: 586 LILAVFEPGIQGARLIYVEFFSKFYHGNGRMFRPF 620

>VATI_CHLPN (Q9Z990) V-type ATP synthase subunit I (EC 3.6.3.14) (V-type ATPase|
           subunit I)
          Length = 660

 Score = 32.0 bits (71), Expect = 0.91
 Identities = 13/47 (27%), Positives = 26/47 (55%)
 Frame = -3

Query: 477 VLLVMETLSAFLHALRLHWVEFQNKFYEGDGYKFAPFSFALISEDEE 337
           V +++  +   +H LRL+++E+ +  ++G G    P    + SED E
Sbjct: 602 VNIILSIMGGVIHGLRLNFIEWYHYSFDGGGRPLRPLRKIVCSEDAE 648


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 73,785,481
Number of Sequences: 219361
Number of extensions: 1507560
Number of successful extensions: 3861
Number of sequences better than 10.0: 29
Number of HSP's better than 10.0 without gapping: 3772
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3860
length of database: 80,573,946
effective HSP length: 103
effective length of database: 57,979,763
effective search space used: 3420806017
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)