>NOTC2_HUMAN (Q04721) Neurogenic locus notch homolog protein 2 precursor (Notch 2)|
            (hN2) [Contains: Notch 2 extracellular truncation; Notch
            2 intracellular domain]
          Length = 2471

 Score = 30.8 bits (68), Expect = 1.5
 Identities = 18/62 (29%), Positives = 28/62 (45%), Gaps = 1/62 (1%)
 Frame = -2

Query: 422  PSAKMPLLHVMSAPSARRLLP-PHVKRRPLPASRTVLLQLHLLNAGVLDLGPLQILHPTP 246
            P A +   H +S  +   + P  H     LP+   +L   H+++ G    G L  LHP P
Sbjct: 2189 PPAPVHAQHALSFSNLHEMQPLAHGASTVLPSVSQLLSHHHIVSPGSGSAGSLSRLHPVP 2248

Query: 245  LP 240
            +P
Sbjct: 2249 VP 2250

>ROBO3_MOUSE (Q9Z2I4) Roundabout homolog 3 precursor (Retinoblastoma-inhibiting|
            gene 1) (Rig-1)
          Length = 1366

 Score = 30.0 bits (66), Expect = 2.5
 Identities = 16/55 (29%), Positives = 19/55 (34%)
 Frame = +1

Query: 154  WKEDGKNLSQQAGRARRISGQEASAPPASGRGVG*RICRGPRSRTPAFSRCSWSS 318
            W E+    S   G      G       + GRG G   CR P S       C WS+
Sbjct: 1300 WGEESGAGSASRGPTSSQRGPHPDGKESQGRGRGLEACRSPNSPQLPLDSCIWST 1354

>WASF1_MOUSE (Q8R5H6) Wiskott-Aldrich syndrome protein family member 1|
           (WASP-family protein member 1) (WAVE-1 protein)
          Length = 559

 Score = 29.6 bits (65), Expect = 3.3
 Identities = 24/84 (28%), Positives = 32/84 (38%), Gaps = 4/84 (4%)
 Frame = -2

Query: 422 PSAKMPLLHVMSAPSARRLL----PPHVKRRPLPASRTVLLQLHLLNAGVLDLGPLQILH 255
           P    PL   +S  S R  +    PP V   P P +  +           L + P  +LH
Sbjct: 325 PPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAP-GVLH 383

Query: 254 PTPLPLAGGAEASWPEMRRALPAC 183
           P P P+A       P + RA P C
Sbjct: 384 PAPPPIAPPLVQPSPPVARAAPVC 407

>WASF1_HUMAN (Q92558) Wiskott-Aldrich syndrome protein family member 1|
           (WASP-family protein member 1) (WAVE-1 protein)
           (Verprolin homology domain-containing protein 1)
          Length = 559

 Score = 29.6 bits (65), Expect = 3.3
 Identities = 24/84 (28%), Positives = 32/84 (38%), Gaps = 4/84 (4%)
 Frame = -2

Query: 422 PSAKMPLLHVMSAPSARRLL----PPHVKRRPLPASRTVLLQLHLLNAGVLDLGPLQILH 255
           P    PL   +S  S R  +    PP V   P P +  +           L + P  +LH
Sbjct: 325 PPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAP-GVLH 383

Query: 254 PTPLPLAGGAEASWPEMRRALPAC 183
           P P P+A       P + RA P C
Sbjct: 384 PAPPPIAPPLVQPSPPVARAAPVC 407

>MYB_XENLA (Q08759) Myb protein|
          Length = 624

 Score = 29.3 bits (64), Expect = 4.3
 Identities = 17/55 (30%), Positives = 25/55 (45%)
 Frame = -2

Query: 398 HVMSAPSARRLLPPHVKRRPLPASRTVLLQLHLLNAGVLDLGPLQILHPTPLPLA 234
           H++  P+ +R +     R P P    +  Q           GPL++LH TPL LA
Sbjct: 433 HLLRTPAIKRSILNSTPRTPTPFKNALAAQ-------EFKHGPLKLLHHTPLHLA 480

>ESAM_HUMAN (Q96AP7) Endothelial cell-selective adhesion molecule precursor|
          Length = 390

 Score = 28.9 bits (63), Expect = 5.7
 Identities = 27/84 (32%), Positives = 35/84 (41%), Gaps = 1/84 (1%)
 Frame = -2

Query: 389 SAPSARRLLPPHVKRRPLPASRTVLLQLHLLNAGVLDLGPLQILHPTPL-PLAGGAEASW 213
           S  SAR L PPH   RP   + T  L    L +    L      HP P+ P+ GG  +S 
Sbjct: 312 SVTSARALRPPHGPPRPGALTPTPSLSSQALPSP--RLPTTDGAHPQPISPIPGGVSSSG 369

Query: 212 PEMRRALPACWLRFLPSSFQAWEL 141
                A+P      +P+  QA  L
Sbjct: 370 LSRMGAVPV----MVPAQSQAGSL 389

>CRF_CANFA (P49926) Corticoliberin precursor (Corticotropin-releasing factor)|
           (CRF) (Corticotropin-releasing hormone)
          Length = 196

 Score = 28.9 bits (63), Expect = 5.7
 Identities = 17/50 (34%), Positives = 26/50 (52%), Gaps = 3/50 (6%)
 Frame = -2

Query: 365 LPPHVKRRPLPASRTVLLQL---HLLNAGVLDLGPLQILHPTPLPLAGGA 225
           LPP  ++   P +R VL ++   + L  G L+  P   L P   P+AGG+
Sbjct: 49  LPPQPQQPQQPQARPVLYRMGEEYFLRLGNLNKSPAAPLLPASSPVAGGS 98

>SMBP2_HUMAN (P38935) DNA-binding protein SMUBP-2 (EC 3.6.1.-) (ATP-dependent|
           helicase IGHMBP2) (Immunoglobulin mu-binding protein 2)
           (SMUBP-2) (Glial factor 1) (GF-1)
          Length = 993

 Score = 28.5 bits (62), Expect = 7.4
 Identities = 15/35 (42%), Positives = 18/35 (51%)
 Frame = +1

Query: 142 SSQAWKEDGKNLSQQAGRARRISGQEASAPPASGR 246
           S  A K  G   S + G  R+  GQEA+AP   GR
Sbjct: 660 SHAATKPQGPATSTRTGSQRQEGGQEAAAPARQGR 694

>OTOF_HUMAN (Q9HC10) Otoferlin (Fer-1-like protein 2)|
          Length = 1997

 Score = 28.5 bits (62), Expect = 7.4
 Identities = 16/34 (47%), Positives = 20/34 (58%)
 Frame = +1

Query: 283  RTPAFSRCSWSSTVRLAGRGRLLTCGGRSLLAEG 384
            R P  S  SW++TVRL  R R+L  GG S  + G
Sbjct: 1232 RPPDRSAPSWNTTVRLLRRCRVLCNGGSSSHSTG 1265

>PYY_HUMAN (P10082) Peptide YY precursor (PYY) (PYY-I) (Peptide tyrosine|
           tyrosine) [Contains: Peptide YY(3-36) (PYY-II)]
          Length = 97

 Score = 28.1 bits (61), Expect = 9.7
 Identities = 19/50 (38%), Positives = 26/50 (52%)
 Frame = -2

Query: 347 RRPLPASRTVLLQLHLLNAGVLDLGPLQILHPTPLPLAGGAEASWPEMRR 198
           RRP PA  TVLL L +    ++D  P++       P A G +AS  E+ R
Sbjct: 5   RRPWPALTTVLLALLVCLGALVDAYPIK-------PEAPGEDASPEELNR 47

>PO23_POPJA (Q05118) Retrovirus-related Pol polyprotein from type-1|
           retrotransposable element R2 (Retrovirus-related Pol
           polyprotein from type I retrotransposable element R2)
           [Includes: Reverse transcriptase (EC 2.7.7.49);
           Endonuclease] (Fragment)
          Length = 606

 Score = 28.1 bits (61), Expect = 9.7
 Identities = 15/39 (38%), Positives = 22/39 (56%)
 Frame = -2

Query: 242 PLAGGAEASWPEMRRALPACWLRFLPSSFQAWELHTQLK 126
           PL  GA   WP  R  +P C +  +P++ +A  +HT LK
Sbjct: 543 PLLLGARGIWP--RANVPTCNILSIPTTLRASCVHTCLK 579

>GP113_HUMAN (Q8IZF5) Probable G-protein coupled receptor 113 precursor|
           (G-protein coupled receptor PGR23)
          Length = 1079

 Score = 28.1 bits (61), Expect = 9.7
 Identities = 25/76 (32%), Positives = 34/76 (44%), Gaps = 2/76 (2%)
 Frame = +1

Query: 208 SGQEASAP-PASGRGVG*RICRGPRSRTPAFSRCSWSSTVRLAGRGRLLTCGGRSLLAEG 384
           +G  A AP P S RG+  R+C       P  S C+ +  + L  R +LL  G  S   E 
Sbjct: 445 AGHVAQAPCPESKRGIVRRLCGADGVWGPVHSSCTDARLLALFTRTKLLQAGQGSPAEEV 504

Query: 385 ADITCR-RGILAEGTS 429
             I  +  G  AE +S
Sbjct: 505 PQILAQLPGQAAEASS 520

>GNEFR_HUMAN (Q9UGK8) Guanine nucleotide exchange factor-related protein|
           (Deafness locus associated putative guanine nucleotide
           exchange factor) (DelGEF)
          Length = 458

 Score = 28.1 bits (61), Expect = 9.7
 Identities = 12/43 (27%), Positives = 20/43 (46%)
 Frame = +1

Query: 304 CSWSSTVRLAGRGRLLTCGGRSLLAEGADITCRRGILAEGTSI 432
           C W  T+ L   G++L+CG  S    G     RR ++ +   +
Sbjct: 108 CGWDFTIMLTENGQVLSCGSNSFGQLGVPHGPRRCVVPQAIEL 150

>PUF68_DROME (Q8T6B9) Poly U-binding splicing factor half pint (68 kDa poly|
           U-binding splicing factor) (Protein half pint) (PUF60
           homolog)
          Length = 637

 Score = 28.1 bits (61), Expect = 9.7
 Identities = 21/61 (34%), Positives = 29/61 (47%), Gaps = 3/61 (4%)
 Frame = -2

Query: 401 LHVMSAPSARRLLPPHVKRRPLPASRTVL---LQLHLLNAGVLDLGPLQILHPTPLPLAG 231
           LH   A +A  LLPP + + P P + ++L     L  L A V  L P  +L    LP+  
Sbjct: 379 LHPALAQAAPALLPPGIFQAPTPVAPSLLGVPAGLQPLQAVVPTLPPPALLATPTLPMTV 438

Query: 230 G 228
           G
Sbjct: 439 G 439

>CWC22_DEBHA (Q6BU84) Pre-mRNA-splicing factor CWC22|
          Length = 637

 Score = 28.1 bits (61), Expect = 9.7
 Identities = 20/63 (31%), Positives = 29/63 (46%), Gaps = 1/63 (1%)
 Frame = +1

Query: 169 KNLS-QQAGRARRISGQEASAPPASGRGVG*RICRGPRSRTPAFSRCSWSSTVRLAGRGR 345
           KNL  ++ GR+R +SG   S   +  R        G  SR+ + SR    S  R   RGR
Sbjct: 537 KNLPPEERGRSRSVSGSSRSGSSSYSRSRSYSRSSGSYSRSRSRSRSRSRSRSRTGSRGR 596

Query: 346 LLT 354
            ++
Sbjct: 597 TMS 599


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 59,925,026
Number of Sequences: 219361
Number of extensions: 1266521
Number of successful extensions: 3642
Number of sequences better than 10.0: 15
Number of HSP's better than 10.0 without gapping: 3565
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3642
length of database: 80,573,946
effective HSP length: 101
effective length of database: 58,418,485
effective search space used: 2511994855
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)