>CAS1_ARATH (P38605) Cycloartenol synthase (EC 5.4.99.8)|
           (2,3-epoxysqualene--cycloartenol cyclase)
          Length = 759

 Score = 74.7 bits (182), Expect = 5e-14
 Identities = 32/38 (84%), Positives = 36/38 (94%)
 Frame = -1

Query: 332 FLQQEIMGVFNKNCMISYSQYRNIFPIWALGEYRCRVL 219
           F QQEIMGVFN+NCMI+Y+ YRNIFPIWALGEYRC+VL
Sbjct: 717 FPQQEIMGVFNRNCMITYAAYRNIFPIWALGEYRCQVL 754

>ERG7_HUMAN (P48449) Lanosterol synthase (EC 5.4.99.7)|
           (Oxidosqualene--lanosterol cyclase)
           (2,3-epoxysqualene--lanosterol cyclase) (OSC)
          Length = 732

 Score = 54.3 bits (129), Expect = 7e-08
 Identities = 22/31 (70%), Positives = 26/31 (83%)
 Frame = -1

Query: 326 QQEIMGVFNKNCMISYSQYRNIFPIWALGEY 234
           Q+ I GVFNK+C ISY+ YRNIFPIWALG +
Sbjct: 689 QENIAGVFNKSCAISYTSYRNIFPIWALGRF 719

>ERG7_RAT (P48450) Lanosterol synthase (EC 5.4.99.7)|
           (Oxidosqualene--lanosterol cyclase)
           (2,3-epoxysqualene--lanosterol cyclase) (OSC)
          Length = 733

 Score = 54.3 bits (129), Expect = 7e-08
 Identities = 22/31 (70%), Positives = 26/31 (83%)
 Frame = -1

Query: 326 QQEIMGVFNKNCMISYSQYRNIFPIWALGEY 234
           Q+ I GVFNK+C ISY+ YRNIFPIWALG +
Sbjct: 690 QENISGVFNKSCAISYTNYRNIFPIWALGRF 720

>ERG7_MOUSE (Q8BLN5) Lanosterol synthase (EC 5.4.99.7)|
           (Oxidosqualene--lanosterol cyclase)
           (2,3-epoxysqualene--lanosterol cyclase) (OSC)
          Length = 733

 Score = 54.3 bits (129), Expect = 7e-08
 Identities = 22/31 (70%), Positives = 26/31 (83%)
 Frame = -1

Query: 326 QQEIMGVFNKNCMISYSQYRNIFPIWALGEY 234
           Q+ I GVFNK+C ISY+ YRNIFPIWALG +
Sbjct: 690 QENISGVFNKSCAISYTSYRNIFPIWALGRF 720

>ERG7_PNECA (Q96WJ0) Lanosterol synthase (EC 5.4.99.7)|
           (Oxidosqualene--lanosterol cyclase)
           (2,3-epoxysqualene--lanosterol cyclase) (OSC)
          Length = 719

 Score = 42.4 bits (98), Expect = 3e-04
 Identities = 21/34 (61%), Positives = 23/34 (67%)
 Frame = -1

Query: 326 QQEIMGVFNKNCMISYSQYRNIFPIWALGEYRCR 225
           Q+ I GVFNKNCMISY  Y+  F I ALG Y  R
Sbjct: 682 QEAIEGVFNKNCMISYPNYKFNFTIKALGMYSKR 715

>ERG7_CANAL (Q04782) Lanosterol synthase (EC 5.4.99.7)|
           (Oxidosqualene--lanosterol cyclase)
           (2,3-epoxysqualene--lanosterol cyclase) (OSC)
          Length = 728

 Score = 39.7 bits (91), Expect = 0.002
 Identities = 17/31 (54%), Positives = 22/31 (70%)
 Frame = -1

Query: 323 QEIMGVFNKNCMISYSQYRNIFPIWALGEYR 231
           ++I GVFN +C I Y  YR +FPI ALG Y+
Sbjct: 689 EDIEGVFNHSCAIEYPSYRFLFPIKALGLYK 719

>ERG7_YEAST (P38604) Lanosterol synthase (EC 5.4.99.7)|
           (Oxidosqualene--lanosterol cyclase)
           (2,3-epoxysqualene--lanosterol cyclase) (OSC)
          Length = 730

 Score = 38.1 bits (87), Expect = 0.006
 Identities = 16/30 (53%), Positives = 20/30 (66%)
 Frame = -1

Query: 323 QEIMGVFNKNCMISYSQYRNIFPIWALGEY 234
           + + GVFN +C I Y  YR +FPI ALG Y
Sbjct: 692 ESVEGVFNHSCAIEYPSYRFLFPIKALGMY 721

>ERG7_SCHPO (Q10231) Lanosterol synthase (EC 5.4.99.7)|
           (Oxidosqualene--lanosterol cyclase)
           (2,3-epoxysqualene--lanosterol cyclase) (OSC)
          Length = 721

 Score = 33.9 bits (76), Expect = 0.10
 Identities = 13/31 (41%), Positives = 21/31 (67%)
 Frame = -1

Query: 326 QQEIMGVFNKNCMISYSQYRNIFPIWALGEY 234
           Q+ + G+FNKN  I+Y  Y+  F I+ LG++
Sbjct: 681 QKSMEGIFNKNVAIAYPNYKLYFSIYTLGKF 711

>SRYC_DROME (P15619) Serendipity locus protein H-1 (Protein wings-down)|
           (Protein pourquoi-pas)
          Length = 869

 Score = 30.0 bits (66), Expect = 1.5
 Identities = 16/42 (38%), Positives = 21/42 (50%)
 Frame = -3

Query: 315 HGSIQQELHDQLFPVQEHLPYLGARRVPLPSLGGGQEIVPCS 190
           H  I+ EL D+L P  + LP   + R+P PSL       P S
Sbjct: 723 HFQIKNELPDELLPDDDFLPCKPSDRLPCPSLESSPFSSPAS 764

>ATG27_DEBHA (Q6BM18) Autophagy-related protein 27 precursor|
          Length = 282

 Score = 30.0 bits (66), Expect = 1.5
 Identities = 12/44 (27%), Positives = 21/44 (47%)
 Frame = -2

Query: 277 PSTGTSSLSGRSESTAAESWGWARNSTMFLLFWLAVYVLEQCMF 146
           P     +  G  +    ESWGW     +FL+ +L++Y++    F
Sbjct: 188 PDNKKDNKKGNDKDDNGESWGWFTWIFIFLVLFLSIYIVGGAWF 231

>SQHC_BRAJA (P54924) Squalene--hopene cyclase (EC 5.4.99.17)|
          Length = 660

 Score = 29.6 bits (65), Expect = 2.0
 Identities = 14/32 (43%), Positives = 17/32 (53%), Gaps = 6/32 (18%)
 Frame = -1

Query: 287 ISYSQYRNIFPIWALGEYR------CRVLGVG 210
           + Y  Y   FP+WAL  YR       RV+GVG
Sbjct: 628 LRYHGYSKFFPLWALARYRNLRNTNSRVVGVG 659

>PI3R4_RAT (P0C0R5) Phosphoinositide 3-kinase regulatory subunit 4 (EC|
           2.7.11.1) (PI3-kinase regulatory subunit 4)
          Length = 1357

 Score = 28.9 bits (63), Expect = 3.3
 Identities = 9/23 (39%), Positives = 16/23 (69%)
 Frame = +2

Query: 152 TLFQHVNRKPKKKEHGTISCPPP 220
           +LF+H++ + KK+    + CPPP
Sbjct: 739 SLFRHLHMRQKKRNGSLLDCPPP 761

>PI3R4_MOUSE (Q8VD65) Phosphoinositide 3-kinase regulatory subunit 4 (EC|
           2.7.11.1) (PI3-kinase regulatory subunit 4)
          Length = 1357

 Score = 28.9 bits (63), Expect = 3.3
 Identities = 9/23 (39%), Positives = 16/23 (69%)
 Frame = +2

Query: 152 TLFQHVNRKPKKKEHGTISCPPP 220
           +LF+H++ + KK+    + CPPP
Sbjct: 739 SLFRHLHMRQKKRNGSLLDCPPP 761

>UBR1_DROME (Q9VX91) Ubiquitin-protein ligase E3 component N-recognin (EC|
           6.-.-.-) (Ubiquitin-protein ligase E3-alpha)
          Length = 1824

 Score = 28.1 bits (61), Expect = 5.7
 Identities = 15/59 (25%), Positives = 28/59 (47%), Gaps = 2/59 (3%)
 Frame = +2

Query: 56  KQIYSSTHRMVKKYILYGYQISTCI*LHYCKH--TLFQHVNRKPKKKEHGTISCPPPRL 226
           K +Y     ++K++ +Y Y        HY K   +  + + R+ +K +   + CPPP L
Sbjct: 847 KGVYELKEHLLKEFNMYFY--------HYTKEDKSKAEELQRERRKAKKQLVCCPPPML 897

>Y304_TREPA (O83326) Hypothetical protein TP0304|
          Length = 1039

 Score = 27.7 bits (60), Expect = 7.4
 Identities = 18/58 (31%), Positives = 29/58 (50%), Gaps = 8/58 (13%)
 Frame = +3

Query: 180 QKRRNMVLFLAHPQDSAAVLSERPDRE------DVPVLGIAD--HAVLVEYSHDLLLK 329
           +K+R  V+  AH QD+    S +P R+       VP LG+     ++L  + H+L  K
Sbjct: 133 KKKRTTVVLYAHTQDAGGSFSSKPSRKIIINDTRVPNLGLGSFKDSLLSIFYHELTHK 190

>ATG27_CANAL (Q5A5S7) Autophagy-related protein 27 precursor|
          Length = 252

 Score = 27.7 bits (60), Expect = 7.4
 Identities = 10/27 (37%), Positives = 17/27 (62%)
 Frame = -2

Query: 226 ESWGWARNSTMFLLFWLAVYVLEQCMF 146
           ESWGW     +FL+ +L++Y++    F
Sbjct: 175 ESWGWFTWIFIFLVLFLSIYIIGGAWF 201

>SQHC_ALIAC (P33247) Squalene--hopene cyclase (EC 5.4.99.17)|
          Length = 630

 Score = 27.3 bits (59), Expect = 9.7
 Identities = 9/19 (47%), Positives = 14/19 (73%)
 Frame = -1

Query: 287 ISYSQYRNIFPIWALGEYR 231
           + Y+ YR++FP  ALG Y+
Sbjct: 606 LGYTMYRHVFPTLALGRYK 624

>SQHC_ZYMMO (P33990) Squalene--hopene cyclase (EC 5.4.99.17)|
          Length = 658

 Score = 27.3 bits (59), Expect = 9.7
 Identities = 11/27 (40%), Positives = 14/27 (51%)
 Frame = -1

Query: 311 GVFNKNCMISYSQYRNIFPIWALGEYR 231
           G F +   + Y  Y   FP+WAL  YR
Sbjct: 618 GGFPRVFYLRYHGYSKYFPLWALARYR 644

>RT03_OENBE (P27754) Mitochondrial ribosomal protein S3|
          Length = 550

 Score = 27.3 bits (59), Expect = 9.7
 Identities = 12/40 (30%), Positives = 23/40 (57%), Gaps = 1/40 (2%)
 Frame = +2

Query: 98  ILYGYQISTCI*LHYCKHTLFQ-HVNRKPKKKEHGTISCP 214
           + +G+++  CI LH+ K T     + R+P++ + G  S P
Sbjct: 51  LTFGFRLGRCIILHFPKRTFIHFFLPRRPRRLKRGKKSRP 90


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 51,315,933
Number of Sequences: 219361
Number of extensions: 1022660
Number of successful extensions: 2707
Number of sequences better than 10.0: 19
Number of HSP's better than 10.0 without gapping: 2658
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2706
length of database: 80,573,946
effective HSP length: 86
effective length of database: 61,708,900
effective search space used: 1481013600
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)