>DLL3_HUMAN (Q9NYJ7) Delta-like protein 3 precursor (Drosophila Delta homolog|
           3)
          Length = 618

 Score = 37.4 bits (85), Expect = 0.010
 Identities = 31/120 (25%), Positives = 43/120 (35%), Gaps = 33/120 (27%)
 Frame = -1

Query: 270 CPCCARFYGM---LALIQCLLHSC*NVSICCGAAE---------------YSCKKFYDEC 145
           C C   FYG+   ++ + C    C N  +C G A+                +C+K  D C
Sbjct: 298 CTCPRGFYGLRCEVSGVTCADGPCFNGGLCVGGADPDSAYICHCPPGFQGSNCEKRVDRC 357

Query: 144 LLHSC*NVSIC------------CGAAEYSCKKFYDECLLHSC*NVSICC---GAAEYSC 10
            L  C N  +C             G A   C+   D+C   +C N   C    GA   SC
Sbjct: 358 SLQPCRNGGLCLDLGHALRCRCRAGFAGPRCEHDLDDCAGRACANGGTCVEGGGAHRCSC 417

>DLLA_BRARE (Q6DI48) Delta-like protein A precursor (DeltaA protein)|
          Length = 772

 Score = 37.0 bits (84), Expect = 0.013
 Identities = 31/116 (26%), Positives = 42/116 (36%), Gaps = 29/116 (25%)
 Frame = -1

Query: 270 CPCCARFYGM---LALIQCLLHSC*NVSICC-------------GAAEYSCKKFYDECLL 139
           C C   FYG    L+ + C    C N   C              G A ++C+K  D C  
Sbjct: 354 CTCPPGFYGKNCELSAMTCADGPCFNGGRCADNPDGGYFCQCPTGYAGFNCEKKIDHCSS 413

Query: 138 HSC*NVSICC------------GAAEYSCKKFYDECLLHSC*NVSICC-GAAEYSC 10
             C N + C             G    +C +  DEC ++ C N   C  GA+ Y C
Sbjct: 414 SPCSNGARCVDLVNSYLCQCPDGFTGMNCDRAGDECSMYPCQNGGTCQEGASGYMC 469

>DLL3_MOUSE (O88516) Delta-like protein 3 precursor (Drosophila Delta homolog|
           3) (M-Delta-3)
          Length = 592

 Score = 34.7 bits (78), Expect = 0.063
 Identities = 29/120 (24%), Positives = 42/120 (35%), Gaps = 33/120 (27%)
 Frame = -1

Query: 270 CPCCARFYGM---LALIQCLLHSC*NVSICCGAAE---------------YSCKKFYDEC 145
           C C   FYG+   ++ + C    C N  +C G  +                +C+K  D C
Sbjct: 296 CACPRGFYGLRCEVSGVTCADGPCFNGGLCVGGEDPDSAYVCHCPPGFQGSNCEKRVDRC 355

Query: 144 LLHSC*NVSIC------------CGAAEYSCKKFYDECLLHSC*NVSICC---GAAEYSC 10
            L  C N  +C             G A   C+   D+C   +C N   C    G+   SC
Sbjct: 356 SLQPCQNGGLCLDLGHALRCRCRAGFAGPRCEHDLDDCAGRACANGGTCVEGGGSRRCSC 415

>CUBN_CANFA (Q9TU53) Cubilin precursor|
          Length = 3620

 Score = 33.5 bits (75), Expect = 0.14
 Identities = 28/97 (28%), Positives = 37/97 (38%), Gaps = 12/97 (12%)
 Frame = -1

Query: 261 CARFYGMLALIQCLLHSC*NVSICCGAAEYSCKKFYDECLLHSC*NVS--------IC-- 112
           C+   G L L  CL     N     G     C +  D CL H C N          +C  
Sbjct: 363 CSSVLGSLPLCTCLPGYTGN-----GYGPNGCAQLSDTCLSHPCLNGQCIETVSGYLCKC 417

Query: 111 -CGAAEYSCKKFYDECLLHSC*NVSICC-GAAEYSCQ 7
             G A  +C +  +ECL + C N   C  G   +SC+
Sbjct: 418 ESGWAGINCTENINECLSNPCFNGGTCVDGVNAFSCE 454

>DLL3_RAT (O88671) Delta-like protein 3 precursor (Drosophila Delta homolog|
           3)
          Length = 589

 Score = 33.1 bits (74), Expect = 0.18
 Identities = 29/120 (24%), Positives = 41/120 (34%), Gaps = 33/120 (27%)
 Frame = -1

Query: 270 CPCCARFYGM---LALIQCLLHSC*NVSICCGAAE---------------YSCKKFYDEC 145
           C C   FYG    ++ + C    C N  +C G  +                +C++  D C
Sbjct: 300 CACPRGFYGPRCEVSGVTCADGPCFNGGLCVGGEDPDSAYVCHCPPAFQGSNCERRVDRC 359

Query: 144 LLHSC*NVSIC------------CGAAEYSCKKFYDECLLHSC*NVSICC---GAAEYSC 10
            L  C N  +C             G A   C+   D+C   +C N   C    GA   SC
Sbjct: 360 SLQPCQNGGLCLDLGHALRCRCRAGFAGPRCEHDLDDCAGRACANGGTCVEGGGARRCSC 419

>SLIT1_RAT (O88279) Slit homolog 1 protein precursor (Slit-1) (Multiple|
            epidermal growth factor-like domains 4)
          Length = 1531

 Score = 32.3 bits (72), Expect = 0.31
 Identities = 29/117 (24%), Positives = 44/117 (37%), Gaps = 30/117 (25%)
 Frame = -1

Query: 270  CPCCARFYGMLALIQ---CLLHSC*NVSICC-GAAEYSCK-----------KFYDECL-- 142
            C C + F G+   +    C+ H C N  +C  G   Y+C+           +  D C   
Sbjct: 991  CSCPSGFEGLTCGMNTDDCVKHDCVNGGVCVDGIGNYTCQCPLQYTGRACEQLVDFCSPD 1050

Query: 141  LHSC*NVSICCGAAEY------------SCKKFYDECLLHSC*NVSICCGAA-EYSC 10
            L+ C + + C G  E             +C K  D+C  H C N + C      Y+C
Sbjct: 1051 LNPCQHEAQCVGTPEGPRCECVPGYTGDNCSKNQDDCKDHQCQNGAQCVDEINSYAC 1107



 Score = 30.0 bits (66), Expect = 1.5
 Identities = 18/71 (25%), Positives = 26/71 (36%), Gaps = 16/71 (22%)
 Frame = -1

Query: 171  SCKKFYDECLLHSC*NVSIC---------------CGAAEYSCKKFYDECLLHSC*NVSI 37
            +C+   D C  + C N   C                G    +C    D+C+ H C N  +
Sbjct: 960  NCEVSLDSCSSNPCGNGGTCHAQEGEDAGFTCSCPSGFEGLTCGMNTDDCVKHDCVNGGV 1019

Query: 36   CC-GAAEYSCQ 7
            C  G   Y+CQ
Sbjct: 1020 CVDGIGNYTCQ 1030

>NOTCH_DROME (P07207) Neurogenic locus Notch protein precursor|
          Length = 2703

 Score = 31.6 bits (70), Expect = 0.53
 Identities = 22/70 (31%), Positives = 32/70 (45%), Gaps = 16/70 (22%)
 Frame = -1

Query: 171 SCKKFYDECLLHSC*NVSICC-GAAEYSCK-------KF----YDECLLHS---C*NVSI 37
           +C++ YD+CL H C N   C  G ++Y+C+       +F     DEC       C N + 
Sbjct: 289 NCEQNYDDCLGHLCQNGGTCIDGISDYTCRCPPNFTGRFCQDDVDECAQRDHPVCQNGAT 348

Query: 36  CCGA-AEYSC 10
           C      YSC
Sbjct: 349 CTNTHGSYSC 358



 Score = 29.6 bits (65), Expect = 2.0
 Identities = 21/66 (31%), Positives = 27/66 (40%), Gaps = 13/66 (19%)
 Frame = -1

Query: 168 CKKFYDECLLHSC*NVSICCGAAE-YSC---KKFY--------DECLLHSC*NVSIC-CG 28
           C+K  DEC+   C N  +C      Y C   + FY        DEC  + C N   C  G
Sbjct: 712 CEKNVDECISSPCANNGVCIDQVNGYKCECPRGFYDAHCLSDVDECASNPCVNEGRCEDG 771

Query: 27  AAEYSC 10
             E+ C
Sbjct: 772 INEFIC 777



 Score = 28.1 bits (61), Expect = 5.9
 Identities = 19/63 (30%), Positives = 25/63 (39%), Gaps = 12/63 (19%)
 Frame = -1

Query: 186  GAAEYSCKKFYDECLLHSC*NVSIC---CGAAEYSCKKFY---------DECLLHSC*NV 43
            G A   C+K  DEC    C N   C    GA E  C++ +         D+C  + C N 
Sbjct: 1174 GYAGSYCQKEIDECQSQPCQNGGTCRDLIGAYECQCRQGFQGQNCELNIDDCAPNPCQNG 1233

Query: 42   SIC 34
              C
Sbjct: 1234 GTC 1236

>PRP4B_HUMAN (Q13523) Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1)|
           (PRP4 pre-mRNA-processing factor 4 homolog) (PRP4
           kinase)
          Length = 1007

 Score = 31.2 bits (69), Expect = 0.69
 Identities = 17/67 (25%), Positives = 32/67 (47%)
 Frame = +3

Query: 9   DKNIRRLHNKLIHSSRNAKDTRHRIFYKNIRRLHNKLIHSSRNAKDTRHRIFYKNIRRLH 188
           +K+I   + ++       K +RH+      R  H K  HSS   KD +H+  +K+ +   
Sbjct: 21  EKSINEENGEVSEDQSQNKHSRHKKKKHKHRSKHKKHKHSSEEDKDKKHKHKHKHKKHKR 80

Query: 189 NKLIHSS 209
            ++I +S
Sbjct: 81  KEVIDAS 87

>FBP1_STRPU (P10079) Fibropellin-1 precursor (Fibropellin-I) (Epidermal growth|
            factor-related protein 1) (UEGF-1)
          Length = 1064

 Score = 30.8 bits (68), Expect = 0.90
 Identities = 28/116 (24%), Positives = 40/116 (34%), Gaps = 28/116 (24%)
 Frame = -1

Query: 270  CPCCARFYGMLA---LIQCLLHSC*NVSICC------------GAAEYSCKKFYDECLLH 136
            C C A + G++    + +C    C N  +C             G    +C+   DEC   
Sbjct: 770  CQCVAGYTGVICETDIDECASAPCQNGGVCTDTINGYICACVPGFTGSNCETNIDECASD 829

Query: 135  SC*NVSICCGAA---------EYS---CKKFYDECLLHSC*NVSICCG-AAEYSCQ 7
             C N  IC              YS   C+   D C    C N + C    A+Y C+
Sbjct: 830  PCLNGGICVDGVNGFVCQCPPNYSGTYCEISLDACRSMPCQNGATCVNVGADYVCE 885

>PALA_SCHPO (Q09807) pH-response regulator protein palA/rim20|
          Length = 701

 Score = 30.4 bits (67), Expect = 1.2
 Identities = 13/53 (24%), Positives = 35/53 (66%), Gaps = 6/53 (11%)
 Frame = +3

Query: 87  YKNIRRLHNKLIHSSRNAKDTRHRIFYKNIRRLHNKL------IHSSKNAKDT 227
           Y++  +  +++I+S +++++ + + FY ++ +LH ++      + +S+NAKDT
Sbjct: 439 YRHCCQALDEIINSVKSSQNMKEKGFYSDVIKLHEEVSLLKVNVENSQNAKDT 491



 Score = 29.3 bits (64), Expect = 2.6
 Identities = 12/45 (26%), Positives = 31/45 (68%), Gaps = 6/45 (13%)
 Frame = +3

Query: 33  NKLIHSSRNAKDTRHRIFYKNIRRLHNKL------IHSSRNAKDT 149
           +++I+S +++++ + + FY ++ +LH ++      + +S+NAKDT
Sbjct: 447 DEIINSVKSSQNMKEKGFYSDVIKLHEEVSLLKVNVENSQNAKDT 491

>PRP4B_MOUSE (Q61136) Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1)|
           (PRP4 pre-mRNA-processing factor 4 homolog) (Pre-mRNA
           protein kinase)
          Length = 1007

 Score = 30.4 bits (67), Expect = 1.2
 Identities = 21/94 (22%), Positives = 40/94 (42%)
 Frame = +3

Query: 9   DKNIRRLHNKLIHSSRNAKDTRHRIFYKNIRRLHNKLIHSSRNAKDTRHRIFYKNIRRLH 188
           +K++   + ++       K +RH+      R  H K  HSS   +D +H+  +K+ +   
Sbjct: 22  EKSVNEENGEVSEDQSQNKHSRHKKKKHKHRSKHKKHKHSSEEDRDKKHKHKHKHKKHKR 81

Query: 189 NKLIHSSKNAKDTG*GLASHKTWHNKDIKASSDL 290
            ++I +S        GL+  K     D+    DL
Sbjct: 82  KEVIEASDKE-----GLSPAKRTKLDDLALLEDL 110

>NOTC2_HUMAN (Q04721) Neurogenic locus notch homolog protein 2 precursor (Notch|
           2) (hN2) [Contains: Notch 2 extracellular truncation;
           Notch 2 intracellular domain]
          Length = 2471

 Score = 30.4 bits (67), Expect = 1.2
 Identities = 28/118 (23%), Positives = 41/118 (34%), Gaps = 31/118 (26%)
 Frame = -1

Query: 270 CPCCARFYGMLA---LIQCLLHSC*NVSICCGAAEYS-------------CKKFYDECLL 139
           C C   F G       + C    C N   C    +++             C++  D+C  
Sbjct: 207 CQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCPN 266

Query: 138 HSC*NVSICC-GAAEYSCK-----------KFYDECLL--HSC*NVSICCGA-AEYSC 10
           H C N  +C  G   Y+C+           +  DECLL  ++C N   C      Y C
Sbjct: 267 HRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTCANRNGGYGC 324

>CUBN_HUMAN (O60494) Cubilin precursor (Intrinsic factor-cobalamin receptor)|
           (Intrinsic factor-vitamin B12 receptor) (460 kDa
           receptor) (Intestinal intrinsic factor receptor)
          Length = 3623

 Score = 30.0 bits (66), Expect = 1.5
 Identities = 26/97 (26%), Positives = 35/97 (36%), Gaps = 12/97 (12%)
 Frame = -1

Query: 261 CARFYGMLALIQCLLHSC*NVSICCGAAEYSCKKFYDECLLHSC*NVSICCGAAEYSCK- 85
           C+   G L L  CL     N     G     C +  + CL H C N       + Y CK 
Sbjct: 366 CSSTLGSLPLCTCLPGYTGN-----GYGPNGCVQLSNICLSHPCLNGQCIDTVSGYFCKC 420

Query: 84  ----------KFYDECLLHSC*NVSICC-GAAEYSCQ 7
                     +  +ECL + C N   C  G   +SC+
Sbjct: 421 DSGWTGVNCTENINECLSNPCLNGGTCVDGVDSFSCE 457

>SLIT1_HUMAN (O75093) Slit homolog 1 protein precursor (Slit-1) (Multiple|
            epidermal growth factor-like domains 4)
          Length = 1534

 Score = 30.0 bits (66), Expect = 1.5
 Identities = 29/117 (24%), Positives = 43/117 (36%), Gaps = 30/117 (25%)
 Frame = -1

Query: 270  CPCCARFYGMLALIQ---CLLHSC*NVSICC-GAAEYSCK-----------KFYDECL-- 142
            C C   F G    +    C+ H+C N  +C  G   Y+C+           +  D C   
Sbjct: 991  CSCPTGFEGPTCGVNTDDCVDHACANGGVCVDGVGNYTCQCPLQYEGKACEQLVDLCSPD 1050

Query: 141  LHSC*NVSICCGA------------AEYSCKKFYDECLLHSC*NVSICCGAA-EYSC 10
            L+ C + + C G             A  +C +  D+C  H C N + C      YSC
Sbjct: 1051 LNPCQHEAQCVGTPDGPRCECMPGYAGDNCSENQDDCRDHRCQNGAQCMDEVNSYSC 1107



 Score = 27.3 bits (59), Expect = 10.0
 Identities = 11/30 (36%), Positives = 17/30 (56%), Gaps = 1/30 (3%)
 Frame = -1

Query: 93   SCKKFYDECLLHSC*NVSICC-GAAEYSCQ 7
            +C    D+C+ H+C N  +C  G   Y+CQ
Sbjct: 1001 TCGVNTDDCVDHACANGGVCVDGVGNYTCQ 1030

>NOTC1_HUMAN (P46531) Neurogenic locus notch homolog protein 1 precursor (Notch 1)|
            (hN1) (Translocation-associated notch protein TAN-1)
            [Contains: Notch 1 extracellular truncation; Notch 1
            intracellular domain]
          Length = 2556

 Score = 30.0 bits (66), Expect = 1.5
 Identities = 19/57 (33%), Positives = 22/57 (38%), Gaps = 12/57 (21%)
 Frame = -1

Query: 168  CKKFYDECLLHSC*NVSICCG-AAEYSCK-----------KFYDECLLHSC*NVSIC 34
            C+   DEC    C N + C      YSCK           +  DECL H C N   C
Sbjct: 1143 CEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQNGGTC 1199

>GSTP_DIRIM (P46426) Glutathione S-transferase (EC 2.5.1.18) (GST class-pi)|
          Length = 208

 Score = 30.0 bits (66), Expect = 1.5
 Identities = 18/54 (33%), Positives = 28/54 (51%), Gaps = 1/54 (1%)
 Frame = +3

Query: 18  IRRLHNKL-IHSSRNAKDTRHRIFYKNIRRLHNKLIHSSRNAKDTRHRIFYKNI 176
           +R L  K  ++   NA+ +   +FY+ IR LH+K       A +T+   F KNI
Sbjct: 67  LRHLARKFNLNGENNAETSYVDMFYEGIRDLHSKYTRMIYEAYETQKDPFIKNI 120

>NOTC2_MOUSE (O35516) Neurogenic locus notch homolog protein 2 precursor (Notch|
           2) (Motch B) [Contains: Notch 2 extracellular
           truncation; Notch 2 intracellular domain]
          Length = 2470

 Score = 29.6 bits (65), Expect = 2.0
 Identities = 18/60 (30%), Positives = 28/60 (46%), Gaps = 14/60 (23%)
 Frame = -1

Query: 171 SCKKFYDECLLHSC*NVSICC-GAAEYSCK-----------KFYDECLL--HSC*NVSIC 34
           +C++  D+C  H C N  +C  G   Y+C+           +  DECLL  ++C N   C
Sbjct: 254 TCERNIDDCPNHKCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTC 313



 Score = 28.5 bits (62), Expect = 4.5
 Identities = 30/115 (26%), Positives = 37/115 (32%), Gaps = 28/115 (24%)
 Frame = -1

Query: 270  CPCCARFYG---MLALIQCLLHSC*NVSIC----------CGAAEYS--CKKFYDECLLH 136
            C C   F G      + +CL   C N   C          C A  +   C+   DEC   
Sbjct: 933  CQCHPGFIGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCTCPAGFHGVHCENNIDECTES 992

Query: 135  SC*NVSICC-GAAEYS-----------CKKFYDECLLHSC*NVSICC-GAAEYSC 10
            SC N   C  G   +S           C    +EC  + C N   C  G   Y C
Sbjct: 993  SCFNGGTCVDGINSFSCLCPVGFTGPFCLHDINECSSNPCLNAGTCVDGLGTYRC 1047



 Score = 28.1 bits (61), Expect = 5.9
 Identities = 24/97 (24%), Positives = 38/97 (39%), Gaps = 24/97 (24%)
 Frame = -1

Query: 228  QCLLHSC*NVSICCGAAEY-----------SCKKFYDECLLHSC*NVSIC---------- 112
            +CL + C + +   G + Y           +C+   +ECL + C N   C          
Sbjct: 721  ECLSNPCIHGNCTGGLSGYKCLCDAGWVGVNCEVDKNECLSNPCQNGGTCNNLVNGYRCT 780

Query: 111  C--GAAEYSCKKFYDECLLHSC*NVSICC-GAAEYSC 10
            C  G   Y+C+   DEC  + C N   C    + Y+C
Sbjct: 781  CKKGFKGYNCQVNIDECASNPCLNQGTCFDDVSGYTC 817

>NOTCH_XENLA (P21783) Neurogenic locus notch protein homolog precursor (XOTCH|
            protein)
          Length = 2524

 Score = 29.6 bits (65), Expect = 2.0
 Identities = 20/72 (27%), Positives = 28/72 (38%), Gaps = 15/72 (20%)
 Frame = -1

Query: 204  NVSICCGAAEYS---CKKFYDECLLHSC*NVSIC------------CGAAEYSCKKFYDE 70
            N   C   A Y+   C++  DEC  + C N + C             G    +C +  +E
Sbjct: 1126 NTHFCRCQAGYTGSYCEEQVDECSPNPCQNGATCTDYLGGYSCECVAGYHGVNCSEEINE 1185

Query: 69   CLLHSC*NVSIC 34
            CL H C N   C
Sbjct: 1186 CLSHPCQNGGTC 1197

>Y244_BUCAP (Q8K9R6) UPF0125 protein BUsg244|
          Length = 95

 Score = 29.3 bits (64), Expect = 2.6
 Identities = 12/31 (38%), Positives = 19/31 (61%)
 Frame = +3

Query: 84  FYKNIRRLHNKLIHSSRNAKDTRHRIFYKNI 176
           FYKN   ++NKL+H + N K+      Y+N+
Sbjct: 47  FYKNNVGIYNKLVHLNENVKNGDRIEIYRNL 77

>NOTC1_BRARE (P46530) Neurogenic locus notch homolog protein 1 precursor|
          Length = 2437

 Score = 29.3 bits (64), Expect = 2.6
 Identities = 28/108 (25%), Positives = 39/108 (36%), Gaps = 21/108 (19%)
 Frame = -1

Query: 270  CPCCARFYGMLALIQCLLHS-----C*NVSICCGAAEYS---CKKFYDECLLHSC*NVSI 115
            C   AR  G+   + C  H+       N  +C   A Y+   C++  DEC  + C N + 
Sbjct: 1099 CEVAARQQGVSVAVLCR-HAGQCVDAGNTHLCRCQAGYTGSYCQEQVDECQPNPCQNGAT 1157

Query: 114  CC------------GAAEYSCKKFYDECLLHSC*NVSICCGAAE-YSC 10
            C             G    +C K  +ECL   C N   C      Y C
Sbjct: 1158 CTDYLGGYSCECVPGYHGMNCSKEINECLSQPCQNGGTCIDLVNTYKC 1205



 Score = 29.3 bits (64), Expect = 2.6
 Identities = 20/79 (25%), Positives = 30/79 (37%), Gaps = 17/79 (21%)
 Frame = -1

Query: 195 ICCGAAEYS---CKKFYDECLLHSC*NVSICC-------------GAAEYSCKKFYDECL 64
           +C    EY+   C++ Y  CL   C +   C              G    +C+   D+C 
Sbjct: 202 LCRCPPEYTGPHCQRLYQPCLPSPCRSGGTCVQTSDTTHTCSCLPGFTGQTCEHNVDDCT 261

Query: 63  LHSC*NVSICC-GAAEYSC 10
            H+C N   C  G   Y+C
Sbjct: 262 QHACENGGPCIDGINTYNC 280

>HIS8_BLOFL (Q7VQW9) Histidinol-phosphate aminotransferase (EC 2.6.1.9)|
           (Imidazole acetol-phosphate transaminase)
          Length = 356

 Score = 29.3 bits (64), Expect = 2.6
 Identities = 13/60 (21%), Positives = 29/60 (48%)
 Frame = -2

Query: 191 VVEPPNILVKNSMTSVFCIPARMYQFVVEPPNILVKNSMTSVFCIPARMYQFVVEPPNIL 12
           +++   +LV +     FC  A + Q + E PN+++  +++  F +      F +  P I+
Sbjct: 171 IIQNKALLVCDEAYIDFCRHASLIQLLTEYPNLIILRTLSKAFALAGLRCGFTLANPKII 230



 Score = 28.5 bits (62), Expect = 4.5
 Identities = 14/52 (26%), Positives = 26/52 (50%)
 Frame = -2

Query: 221 FCILARMYQFVVEPPNILVKNSMTSVFCIPARMYQFVVEPPNILVKNSMTSV 66
           FC  A + Q + E PN+++  +++  F +      F +  P I+  N +T V
Sbjct: 187 FCRHASLIQLLTEYPNLIILRTLSKAFALAGLRCGFTLANPKII--NLLTKV 236

>DL_DROME (P10041) Neurogenic locus protein delta precursor|
          Length = 833

 Score = 29.3 bits (64), Expect = 2.6
 Identities = 28/112 (25%), Positives = 35/112 (31%), Gaps = 25/112 (22%)
 Frame = -1

Query: 270 CPCCARFYGM---LALIQCLLHSC*NVSIC---------CGAAEYSCKKFYDECLLHSC* 127
           C C   + G    L L  C  + C N   C          G +   C+   D+CL H C 
Sbjct: 404 CECPIGYSGPNCDLQLDNCSPNPCINGGSCQPSGKCICPAGFSGTRCETNIDDCLGHQCE 463

Query: 126 NVSICC------------GAAEYSCKKFYDECLLHSC*NVSICCGA-AEYSC 10
           N   C             G     C    D CL+  C N   C     +Y C
Sbjct: 464 NGGTCIDMVNQYRCQCVPGFHGTHCSSKVDLCLIRPCANGGTCLNLNNDYQC 515

>SLIT1_MOUSE (Q80TR4) Slit homolog 1 protein precursor (Slit-1)|
          Length = 1531

 Score = 29.3 bits (64), Expect = 2.6
 Identities = 26/117 (22%), Positives = 44/117 (37%), Gaps = 30/117 (25%)
 Frame = -1

Query: 270  CPCCARFYGMLALIQ---CLLHSC*NVSICC-GAAEYSCK-----------KFYDECL-- 142
            C C + F G    +    C+ H+C N  +C  G   Y+C+           +  D C   
Sbjct: 991  CSCPSGFEGPTCGVDTDDCVKHACVNGGVCVDGVGNYTCQCPLQYTGRACEQLVDFCSPD 1050

Query: 141  LHSC*NVSICCGAAEY------------SCKKFYDECLLHSC*NVSICCGAA-EYSC 10
            ++ C + + C G  +             +C +  D+C  H C N + C      Y+C
Sbjct: 1051 MNPCQHEAQCVGTPDGPRCECMLGYTGDNCSENQDDCKDHKCQNGAQCVDEVNSYAC 1107



 Score = 28.5 bits (62), Expect = 4.5
 Identities = 18/70 (25%), Positives = 26/70 (37%), Gaps = 16/70 (22%)
 Frame = -1

Query: 168  CKKFYDECLLHSC*NVSIC---------------CGAAEYSCKKFYDECLLHSC*NVSIC 34
            C+   D C  + C N   C                G    +C    D+C+ H+C N  +C
Sbjct: 961  CEVSLDGCSSNPCGNGGTCHAQEGEDAGFTCSCPSGFEGPTCGVDTDDCVKHACVNGGVC 1020

Query: 33   C-GAAEYSCQ 7
              G   Y+CQ
Sbjct: 1021 VDGVGNYTCQ 1030

>K0317_MOUSE (Q8CHG5) Protein KIAA0317|
          Length = 823

 Score = 28.9 bits (63), Expect = 3.4
 Identities = 22/67 (32%), Positives = 33/67 (49%), Gaps = 1/67 (1%)
 Frame = +3

Query: 18  IRRLHNKLIHSSRNAKDTRHRIFYKNIRRLHNKLIHSSRNAKDTRHRIFYKNIRRLHNKL 197
           IR LH K I  S   +D +   F + +R++H K  HS    K +RH +   +++   N  
Sbjct: 426 IRSLH-KNIGGSETFQD-KVNFFQRELRQVHMKRPHSKVTLKVSRHALLESSLKATRNFS 483

Query: 198 IHS-SKN 215
           I   SKN
Sbjct: 484 ISDWSKN 490

>K0317_HUMAN (O15033) Protein KIAA0317|
          Length = 823

 Score = 28.9 bits (63), Expect = 3.4
 Identities = 22/67 (32%), Positives = 33/67 (49%), Gaps = 1/67 (1%)
 Frame = +3

Query: 18  IRRLHNKLIHSSRNAKDTRHRIFYKNIRRLHNKLIHSSRNAKDTRHRIFYKNIRRLHNKL 197
           IR LH K I  S   +D +   F + +R++H K  HS    K +RH +   +++   N  
Sbjct: 426 IRSLH-KNIGGSETFQD-KVNFFQRELRQVHMKRPHSKVTLKVSRHALLESSLKATRNFS 483

Query: 198 IHS-SKN 215
           I   SKN
Sbjct: 484 ISDWSKN 490

>DLLD_BRARE (Q8UWJ4) Delta-like protein D precursor (DeltaD protein) (After|
           eight protein)
          Length = 717

 Score = 28.9 bits (63), Expect = 3.4
 Identities = 24/92 (26%), Positives = 36/92 (39%), Gaps = 4/92 (4%)
 Frame = -1

Query: 270 CPCCARFYGM---LALIQCLLHSC*NVSICCGAAEYSCKKFYDECLLHSC*NVSICCGAA 100
           C C   FYG    L+ + C    C N   C    E     ++ +C +          G A
Sbjct: 350 CTCPPGFYGRNCELSAMTCADGPCFNGGHCADNPEGG---YFCQCPM----------GYA 396

Query: 99  EYSCKKFYDECLLHSC*NVSICCGAAE-YSCQ 7
            ++C+K  D C  + C N + C    + Y CQ
Sbjct: 397 GFNCEKKIDHCSSNPCSNDAQCLDLVDSYLCQ 428



 Score = 28.1 bits (61), Expect = 5.9
 Identities = 21/72 (29%), Positives = 35/72 (48%), Gaps = 4/72 (5%)
 Frame = -1

Query: 243 MLALIQCLLHSC*NVSICCGAAEYSCKKFYDECLLHSC*NVSICCGAA----EYSCKKFY 76
           M+A++ C++ S      C G  E   ++F ++  +    N + C G+A    +  CK F+
Sbjct: 5   MIAVLLCVMIS---QGFCSGVFELKLQEFLNKKGVTG--NANCCKGSAAEGHQCECKTFF 59

Query: 75  DECLLHSC*NVS 40
             CL H   NVS
Sbjct: 60  RICLKHYQANVS 71

>HELS_METJA (Q58524) Putative ski2-type helicase (EC 3.6.1.-) [Contains:|
           Endonuclease PI-MjaHel (EC 3.1.-.-) (Mja Hel intein)
           (Mja Pep3 intein)]
          Length = 1195

 Score = 28.9 bits (63), Expect = 3.4
 Identities = 14/40 (35%), Positives = 22/40 (55%)
 Frame = +3

Query: 105 LHNKLIHSSRNAKDTRHRIFYKNIRRLHNKLIHSSKNAKD 224
           LH K     R +K   H I+ K +R++ NKL   +K+ K+
Sbjct: 490 LHKKYFLKCRISKGVAHYIYSKKLRKIFNKLNMLTKDNKN 529



 Score = 27.7 bits (60), Expect = 7.7
 Identities = 13/40 (32%), Positives = 22/40 (55%)
 Frame = +3

Query: 27  LHNKLIHSSRNAKDTRHRIFYKNIRRLHNKLIHSSRNAKD 146
           LH K     R +K   H I+ K +R++ NKL   +++ K+
Sbjct: 490 LHKKYFLKCRISKGVAHYIYSKKLRKIFNKLNMLTKDNKN 529

>CRUM1_MOUSE (Q8VHS2) Crumbs homolog 1 precursor|
          Length = 1405

 Score = 28.9 bits (63), Expect = 3.4
 Identities = 25/89 (28%), Positives = 32/89 (35%), Gaps = 24/89 (26%)
 Frame = -1

Query: 201 VSICC-GAAEYSCKKFYDECLLHSC*NVSICCG-AAEYSCKKFYDE-------------- 70
           V IC  G     C++  DECLLH C N   C      Y+C   +D+              
Sbjct: 381 VCICQPGFTGIHCEEDVDECLLHPCLNGGTCENLPGNYACHCPFDDTSRTFYGGENCSEI 440

Query: 69  ---CLLHSC*NVSICC-----GAAEYSCQ 7
              C  H C N   C      G   ++CQ
Sbjct: 441 LLGCTHHQCLNNGKCIPHFQNGQHGFTCQ 469



 Score = 28.5 bits (62), Expect = 4.5
 Identities = 20/68 (29%), Positives = 26/68 (38%), Gaps = 12/68 (17%)
 Frame = -1

Query: 168  CKKFYDECLLHSC*NVSICCGAAEY-----------SCKKFYDECLLHSC*NVSICCGAA 22
            C+   DEC    C + +   G A Y           +C+   D C  H C N + C   A
Sbjct: 1173 CEINIDECFSSPCIHGNCSDGVAAYHCRCEPGYTGVNCEVDVDNCKSHQCANGATCVPEA 1232

Query: 21   E-YSCQKF 1
              YSC  F
Sbjct: 1233 HGYSCLCF 1240

>PA21B_PIG (P00592) Phospholipase A2, major isoenzyme precursor (EC 3.1.1.4)|
           (Phosphatidylcholine 2-acylhydrolase) (Group IB
           phospholipase A2)
          Length = 146

 Score = 28.5 bits (62), Expect = 4.5
 Identities = 15/48 (31%), Positives = 21/48 (43%)
 Frame = -1

Query: 156 YDECLLHSC*NVSICCGAAEYSCKKFYDECLLHSC*NVSICCGAAEYS 13
           Y E   +SC N  I C +   +C+ F   C      N +IC   A Y+
Sbjct: 91  YTESYSYSCSNTEITCNSKNNACEAFICNCDR----NAAICFSKAPYN 134

>REP1_ZYGBA (P13776) Trans-acting factor B (REP1)|
          Length = 357

 Score = 28.5 bits (62), Expect = 4.5
 Identities = 17/58 (29%), Positives = 28/58 (48%)
 Frame = +3

Query: 6   FDKNIRRLHNKLIHSSRNAKDTRHRIFYKNIRRLHNKLIHSSRNAKDTRHRIFYKNIR 179
           F + IR LHN+L  S    ++ R    +      H K++ +    KDT   +FY N++
Sbjct: 275 FWEAIRALHNELRTSPTQLEECRKAAVFL---LGHKKILQTFTKQKDTARALFYINLK 329

>MT1X_HUMAN (P80297) Metallothionein-1X (MT-1X) (Metallothionein-IX) (MT-IX)|
          Length = 61

 Score = 28.5 bits (62), Expect = 4.5
 Identities = 18/61 (29%), Positives = 20/61 (32%)
 Frame = -1

Query: 213 SC*NVSICCGAAEYSCKKFYDECLLHSC*NVSICCGAAEYSCKKFYDECLLHSC*NVSIC 34
           SC  V  C  A    CK    EC   SC     CC      C K    C+     +   C
Sbjct: 6   SCSPVGSCACAGSCKCK----ECKCTSC--KKSCCSCCPVGCAKCAQGCICKGTSDKCSC 59

Query: 33  C 31
           C
Sbjct: 60  C 60

>RPC1_PLAFA (P27625) DNA-directed RNA polymerase III largest subunit (EC 2.7.7.6)|
          Length = 2339

 Score = 28.5 bits (62), Expect = 4.5
 Identities = 15/50 (30%), Positives = 26/50 (52%), Gaps = 4/50 (8%)
 Frame = +3

Query: 9    DKNIRRLHNKLIHSSRNAKDTRHRIFYKN----IRRLHNKLIHSSRNAKD 146
            D N+  +HN   +++ N KD  H  +  N    IR + N+LI+ +   +D
Sbjct: 1175 DSNMNSIHNNDSNNNNNYKDCTHNPYICNESLIIRNIMNRLIYQNIAQED 1224

>NOTC2_RAT (Q9QW30) Neurogenic locus notch homolog protein 2 precursor (Notch|
           2) [Contains: Notch 2 extracellular truncation; Notch 2
           intracellular domain]
          Length = 2471

 Score = 28.1 bits (61), Expect = 5.9
 Identities = 19/67 (28%), Positives = 28/67 (41%), Gaps = 13/67 (19%)
 Frame = -1

Query: 171 SCKKFYDECLLHSC*NVSIC----------C--GAAEYSCKKFYDECLLHSC*NVSICC- 31
           +C+   +ECL + C N   C          C  G   Y+C+   DEC  + C N   C  
Sbjct: 753 NCEVDKNECLSNPCQNGGTCNNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCLD 812

Query: 30  GAAEYSC 10
             + Y+C
Sbjct: 813 DVSGYTC 819



 Score = 27.7 bits (60), Expect = 7.7
 Identities = 30/115 (26%), Positives = 37/115 (32%), Gaps = 28/115 (24%)
 Frame = -1

Query: 270  CPCCARFYG---MLALIQCLLHSC*NVSIC----------CGAAEYS--CKKFYDECLLH 136
            C C   F G      + +CL   C N   C          C A  +   C+   DEC   
Sbjct: 935  CLCLPGFVGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCTCPAGFHGVHCENNIDECTES 994

Query: 135  SC*NVSICC-GAAEYS-----------CKKFYDECLLHSC*NVSICC-GAAEYSC 10
            SC N   C  G   +S           C    +EC  + C N   C  G   Y C
Sbjct: 995  SCFNGGTCVDGINSFSCLCPVGFTGPFCLHDINECSSNPCLNSGTCVDGLGTYRC 1049



 Score = 27.7 bits (60), Expect = 7.7
 Identities = 25/112 (22%), Positives = 39/112 (34%), Gaps = 27/112 (24%)
 Frame = -1

Query: 270  CPCCARFYGMLALI---QCLLHSC*NVSIC----------C--GAAEYSCKKFYDECLLH 136
            C C A + G+   +   +CL + C N   C          C  G   Y+C+   DEC  +
Sbjct: 743  CLCDAGWVGINCEVDKNECLSNPCQNGGTCNNLVNGYRCTCKKGFKGYNCQVNIDECASN 802

Query: 135  SC*NVSICCGAAE------------YSCKKFYDECLLHSC*NVSICCGAAEY 16
             C N   C                  +C+     C  + C N ++C  A  +
Sbjct: 803  PCLNQGTCLDDVSGYTCHCMLPYTGKNCQTVLAPCSPNPCENAAVCKEAPNF 854



 Score = 27.7 bits (60), Expect = 7.7
 Identities = 24/93 (25%), Positives = 34/93 (36%), Gaps = 5/93 (5%)
 Frame = -1

Query: 270 CPCCARFYGMLA---LIQCLLHSC*NVSICCGAAEYSCKKFYDECLLHSC*NVSICCGAA 100
           C C  RF G       + C    C N   C    +++      EC          C    
Sbjct: 207 CQCPQRFTGQHCDSPYVPCAPSPCVNGGTCRQTGDFT-----SECH---------CLPGF 252

Query: 99  EYS-CKKFYDECLLHSC*NVSICC-GAAEYSCQ 7
           E S C++  D+C  H C N  +C  G   Y+C+
Sbjct: 253 EGSNCERNIDDCPNHKCQNGGVCVDGVNTYNCR 285

>CRUM1_HUMAN (P82279) Crumbs homolog 1 precursor|
          Length = 1406

 Score = 28.1 bits (61), Expect = 5.9
 Identities = 24/78 (30%), Positives = 30/78 (38%), Gaps = 14/78 (17%)
 Frame = -1

Query: 201 VSIC-CGAAEYSCKKFYDECLLHSC*NVSIC-CGAAEYS-----------CKKFYDECLL 61
           V IC  G A   C+  +DEC    C N ++C  G   YS           C    DEC  
Sbjct: 133 VCICPAGYAGRFCEIDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECAS 192

Query: 60  HSC*NVSICCG-AAEYSC 10
             C N + C      Y+C
Sbjct: 193 DPCKNEATCLNEIGRYTC 210

>SEMG2_GORGO (Q5U7N3) Semenogelin-2 precursor (Semenogelin II) (SGII)|
          Length = 474

 Score = 27.7 bits (60), Expect = 7.7
 Identities = 18/75 (24%), Positives = 34/75 (45%), Gaps = 1/75 (1%)
 Frame = +3

Query: 33  NKLIHSSRNAKDTRHRIFYKNIRRLHNKLIHSSRNAKDTRHRIFYKNIRRLHNKLIHSSK 212
           ++L H S++   T+  +   N  +   K ++  +      H+I Y++ R    +L H  K
Sbjct: 244 DRLQHGSKDIFTTQDELLVYNKNQHQTKNLNQDQEHGQKAHKISYQSSRTEERQLNHGEK 303

Query: 213 NA-KDTG*GLASHKT 254
           +  KD   G  S +T
Sbjct: 304 SVQKDVSKGSISIQT 318

>MT1A_HUMAN (P04731) Metallothionein-1A (MT-1A) (Metallothionein-IA) (MT-IA)|
          Length = 61

 Score = 27.3 bits (59), Expect = 10.0
 Identities = 17/61 (27%), Positives = 19/61 (31%)
 Frame = -1

Query: 213 SC*NVSICCGAAEYSCKKFYDECLLHSC*NVSICCGAAEYSCKKFYDECLLHSC*NVSIC 34
           SC     C       CK    EC  +SC     CC     SC K    C+         C
Sbjct: 6   SCATGGSCTCTGSCKCK----ECKCNSC--KKSCCSCCPMSCAKCAQGCICKGASEKCSC 59

Query: 33  C 31
           C
Sbjct: 60  C 60

>ATM_ARATH (Q9M3G7) Serine/threonine-protein kinase ATM (EC 2.7.11.1) (Ataxia|
            telangiectasia mutated homolog) (AtATM)
          Length = 3856

 Score = 27.3 bits (59), Expect = 10.0
 Identities = 15/47 (31%), Positives = 24/47 (51%)
 Frame = +3

Query: 129  SRNAKDTRHRIFYKNIRRLHNKLIHSSKNAKDTG*GLASHKTWHNKD 269
            SR +     R   ++++ LHNKLI S  + +DT  G  +   W + D
Sbjct: 2363 SRRSNYLPPRFLSRSLQALHNKLIASEVSQEDTN-GETAETFWQSDD 2408


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 45,022,766
Number of Sequences: 219361
Number of extensions: 872212
Number of successful extensions: 2469
Number of sequences better than 10.0: 37
Number of HSP's better than 10.0 without gapping: 1560
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2393
length of database: 80,573,946
effective HSP length: 78
effective length of database: 63,463,788
effective search space used: 1523130912
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)