>SMAD_LOXAR (Q7Z1Y7) Sphingomyelinase D precursor (EC 3.1.4.41) (SMase D)|
           (Dermonecrotic enzyme)
          Length = 320

 Score = 30.0 bits (66), Expect = 2.8
 Identities = 12/33 (36%), Positives = 18/33 (54%)
 Frame = -2

Query: 131 EHLGLIAPLYASAATVGSCWSADGIDCCILFGL 33
           +++  +A  Y  A   G  W +DGI  C+L GL
Sbjct: 210 DNIDQVANAYKKAGVTGHVWQSDGITNCLLRGL 242

>CF136_HUMAN (Q5SQH8) Protein C6orf136|
          Length = 315

 Score = 28.9 bits (63), Expect = 6.2
 Identities = 11/23 (47%), Positives = 11/23 (47%)
 Frame = +1

Query: 247 FSGRNCFISGAWFPFATPGRGRP 315
           F G  C   GAW PF  PG   P
Sbjct: 111 FEGPPCPYPGAWIPFQVPGTAHP 133

>MDC1_RAT (Q5U2M8) Mediator of DNA damage checkpoint protein 1|
          Length = 1279

 Score = 28.9 bits (63), Expect = 6.2
 Identities = 18/64 (28%), Positives = 28/64 (43%)
 Frame = +2

Query: 218  KDEKKCLCQASPAETALSPEPGFLLQRQGEGGQEKETANDHLLRPNWQVCASLPL*TGIV 397
            +D  +   +  P ETA+ P PG   +   EG  +         +PN +  A   L TG+V
Sbjct: 1036 EDPGEIQVKEEPQETAI-PTPGKRKRDPAEGETQGNPTRSRRTKPNQEAAAPKVLFTGVV 1094

Query: 398  TTEG 409
             + G
Sbjct: 1095 DSRG 1098

>MEPE_HUMAN (Q9NQ76) Matrix extracellular phosphoglycoprotein precursor|
           (Osteoblast/osteocyte factor 45) (OF45)
          Length = 525

 Score = 28.9 bits (63), Expect = 6.2
 Identities = 13/24 (54%), Positives = 16/24 (66%)
 Frame = -1

Query: 327 VSFSWPPSPWRCKRKPGSGDKAVS 256
           V F +PP+P + KRK GS D A S
Sbjct: 370 VEFHYPPAPSKEKRKEGSSDAAES 393

>HIPK3_MOUSE (Q9ERH7) Homeodomain-interacting protein kinase 3 (EC 2.7.11.1)|
           (Fas-interacting serine/threonine-protein kinase) (FIST)
           (Nuclear body-associated kinase 3) (Nbak3) (Androgen
           receptor-interacting nuclear protein kinase) (ANPK)
          Length = 1192

 Score = 28.5 bits (62), Expect = 8.1
 Identities = 23/89 (25%), Positives = 33/89 (37%)
 Frame = +2

Query: 143 TIPILLPCLNSIKLKHSTKLYTRISKDEKKCLCQASPAETALSPEPGFLLQRQGEGGQEK 322
           T+ I  P +  I   H       I  D    L   +PA   L   PG L Q+   G  ++
Sbjct: 622 TLIICPPAIQGIPAAHGKPTSYSIRVDNTVPLVTQAPAVQPLQIRPGVLSQQTWSGRTQQ 681

Query: 323 ETANDHLLRPNWQVCASLPL*TGIVTTEG 409
                 +L P WQ    +      +T+EG
Sbjct: 682 ------MLIPAWQQVTPMAPAAATLTSEG 704

>MPP4_HUMAN (Q96JB8) MAGUK p55 subfamily member 4 (Discs large homolog 6)|
           (Amyotrophic lateral sclerosis 2 chromosomal region
           candidate gene 5 protein)
          Length = 637

 Score = 28.5 bits (62), Expect = 8.1
 Identities = 27/98 (27%), Positives = 43/98 (43%)
 Frame = +2

Query: 152 ILLPCLNSIKLKHSTKLYTRISKDEKKCLCQASPAETALSPEPGFLLQRQGEGGQEKETA 331
           +L   L+S  L+   K+Y  + + ++K L  A+P    LS E   LL R+     E +  
Sbjct: 52  LLYDLLHSPWLQALLKIYDCLQEFKEKKLVPATPHAQVLSYEVVELL-RETPTSPEIQEL 110

Query: 332 NDHLLRPNWQVCASLPL*TGIVTTEGRIPPLPSTVPYS 445
              L  P+++   S          E  +PPLP  +P S
Sbjct: 111 RQMLQAPHFKALLSAHDTIAQKDFEPLLPPLPDNIPES 148

>DNJ5B_MOUSE (Q9CQ94) DnaJ homolog subfamily C member 5B (Beta cysteine string|
           protein) (Beta-CSP)
          Length = 199

 Score = 28.5 bits (62), Expect = 8.1
 Identities = 9/25 (36%), Positives = 16/25 (64%)
 Frame = -1

Query: 159 RSIGIVVKL*TSWSYCTALCICCHC 85
           +++ I++ L T   +C  LC CC+C
Sbjct: 111 KTLFIIIGLLTGCYFCCCLCCCCNC 135

>DNJ5B_HUMAN (Q9UF47) DnaJ homolog subfamily C member 5B (Beta cysteine string|
           protein) (Beta-CSP)
          Length = 199

 Score = 28.5 bits (62), Expect = 8.1
 Identities = 9/25 (36%), Positives = 16/25 (64%)
 Frame = -1

Query: 159 RSIGIVVKL*TSWSYCTALCICCHC 85
           +++ ++V L T   +C  LC CC+C
Sbjct: 111 KALFVIVGLLTGCYFCCCLCCCCNC 135


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 56,746,611
Number of Sequences: 219361
Number of extensions: 1044032
Number of successful extensions: 2582
Number of sequences better than 10.0: 8
Number of HSP's better than 10.0 without gapping: 2516
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2580
length of database: 80,573,946
effective HSP length: 102
effective length of database: 58,199,124
effective search space used: 2735358828
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)