ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | rbart58f03 |
|---|---|
| Clone Library Name | barley_pub |
>CP51_WHEAT (P93596) Cytochrome P450 51 (EC 1.14.13.70) (CYPLI) (P450-LIA1)| (Obtusifoliol 14-alpha demethylase) (Fragment) Length = 453 Score = 181 bits (460), Expect = 3e-46 Identities = 85/86 (98%), Positives = 86/86 (100%) Frame = -3 Query: 355 DRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVSPFPEN 176 DRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVSPFPEN Sbjct: 368 DRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVSPFPEN 427 Query: 175 DWNAMVVGIKGEVMVNYKRRKLVVDN 98 DWNAMVVGIKGEVMVNYKRRKL+VDN Sbjct: 428 DWNAMVVGIKGEVMVNYKRRKLIVDN 453
>CP51_SORBI (P93846) Cytochrome P450 51 (EC 1.14.13.70) (CYPLI) (P450-LIA1)| (Obtusifoliol 14-alpha demethylase) Length = 492 Score = 177 bits (448), Expect = 7e-45 Identities = 83/86 (96%), Positives = 83/86 (96%) Frame = -3 Query: 355 DRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVSPFPEN 176 DRF GREEDK AGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVSPFPEN Sbjct: 407 DRFGPGREEDKAAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVSPFPEN 466 Query: 175 DWNAMVVGIKGEVMVNYKRRKLVVDN 98 DWNAMVVGIKGEVMVNYKRRKLVVDN Sbjct: 467 DWNAMVVGIKGEVMVNYKRRKLVVDN 492
>CP51_MYCVN (Q5IZM4) Cytochrome P450 51 (EC 1.14.13.70) (CYPLI) (P450-LIA1)| (Sterol 14-alpha demethylase) (Lanosterol 14-alpha demethylase) (P450-14DM) Length = 452 Score = 67.4 bits (163), Expect = 8e-12 Identities = 37/83 (44%), Positives = 53/83 (63%), Gaps = 3/83 (3%) Frame = -3 Query: 355 DRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVSPFPE- 179 DR+ R+ED + +++I FG G+H C+G FA +QIKAI++ LLR +EFE+ P PE Sbjct: 369 DRYEKPRQEDLI-NRWTWIPFGAGKHRCVGAAFAQMQIKAIFSVLLREYEFEMAQP-PES 426 Query: 178 --NDWNAMVVGIKGEVMVNYKRR 116 ND + MVV + V Y+RR Sbjct: 427 YQNDHSKMVVQLARPAKVRYRRR 449
>CP51A_RAT (Q64654) Cytochrome P450 51A1 (EC 1.14.13.70) (CYPLI) (P450LI)| (Sterol 14-alpha demethylase) (Lanosterol 14-alpha demethylase) (LDM) (P450-14DM) Length = 503 Score = 65.9 bits (159), Expect = 2e-11 Identities = 31/66 (46%), Positives = 46/66 (69%), Gaps = 1/66 (1%) Frame = -3 Query: 310 FSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVSP-FPENDWNAMVVGIKGEVM 134 F+Y+ FG GRH C+GE FAY+QIK IW+ +LR +EF+L++ FP ++ M+ + V Sbjct: 437 FAYVPFGAGRHRCIGENFAYVQIKTIWSTMLRLYEFDLINGYFPSVNYTTMIHTPENPV- 495 Query: 133 VNYKRR 116 + YKRR Sbjct: 496 IRYKRR 501
>CP51_MYCTU (P0A512) Cytochrome P450 51 (EC 1.14.13.70) (CYPLI) (P450-LIA1)| (Sterol 14-alpha demethylase) (Lanosterol 14-alpha demethylase) (P450-14DM) Length = 451 Score = 65.9 bits (159), Expect = 2e-11 Identities = 37/82 (45%), Positives = 52/82 (63%), Gaps = 3/82 (3%) Frame = -3 Query: 352 RFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVSPFPE-- 179 R+ R+ED + +++I FG GRH C+G FA +QIKAI++ LLR +EFE+ P PE Sbjct: 369 RYEQPRQED-LLNRWTWIPFGAGRHRCVGAAFAIMQIKAIFSVLLREYEFEMAQP-PESY 426 Query: 178 -NDWNAMVVGIKGEVMVNYKRR 116 ND + MVV + V Y+RR Sbjct: 427 RNDHSKMVVQLAQPACVRYRRR 448
>CP51_MYCBO (P0A513) Cytochrome P450 51 (EC 1.14.13.70) (CYPLI) (P450-LIA1)| (Sterol 14-alpha demethylase) (Lanosterol 14-alpha demethylase) (P450-14DM) Length = 451 Score = 65.9 bits (159), Expect = 2e-11 Identities = 37/82 (45%), Positives = 52/82 (63%), Gaps = 3/82 (3%) Frame = -3 Query: 352 RFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVSPFPE-- 179 R+ R+ED + +++I FG GRH C+G FA +QIKAI++ LLR +EFE+ P PE Sbjct: 369 RYEQPRQED-LLNRWTWIPFGAGRHRCVGAAFAIMQIKAIFSVLLREYEFEMAQP-PESY 426 Query: 178 -NDWNAMVVGIKGEVMVNYKRR 116 ND + MVV + V Y+RR Sbjct: 427 RNDHSKMVVQLAQPACVRYRRR 448
>CP51A_PONPY (Q5RE72) Cytochrome P450 51A1 (EC 1.14.13.70) (CYPLI) (P450LI)| (Sterol 14-alpha demethylase) (Lanosterol 14-alpha demethylase) (LDM) (P450-14DM) (P45014DM) Length = 503 Score = 65.1 bits (157), Expect = 4e-11 Identities = 31/66 (46%), Positives = 45/66 (68%), Gaps = 1/66 (1%) Frame = -3 Query: 310 FSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVSP-FPENDWNAMVVGIKGEVM 134 F+Y+ FG GRH C+GE FAY+QIK IW+ +LR +EF+L+ FP ++ M+ + V Sbjct: 437 FAYVPFGAGRHRCIGENFAYVQIKTIWSTMLRLYEFDLIDGYFPTVNYTTMIHTPENPV- 495 Query: 133 VNYKRR 116 + YKRR Sbjct: 496 IRYKRR 501
>CP51A_PIG (O46420) Cytochrome P450 51A1 (EC 1.14.13.70) (CYPLI) (P450LI)| (Sterol 14-alpha demethylase) (Lanosterol 14-alpha demethylase) (LDM) (P450-14DM) Length = 503 Score = 65.1 bits (157), Expect = 4e-11 Identities = 31/66 (46%), Positives = 45/66 (68%), Gaps = 1/66 (1%) Frame = -3 Query: 310 FSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVSP-FPENDWNAMVVGIKGEVM 134 F+Y+ FG GRH C+GE FAY+QIK IW+ +LR +EF+L+ FP ++ M+ + V Sbjct: 437 FAYVPFGAGRHRCIGENFAYVQIKTIWSTMLRLYEFDLIDGYFPTVNYTTMIHTPENPV- 495 Query: 133 VNYKRR 116 + YKRR Sbjct: 496 IRYKRR 501
>CP51A_HUMAN (Q16850) Cytochrome P450 51A1 (EC 1.14.13.70) (CYPLI) (P450LI)| (Sterol 14-alpha demethylase) (Lanosterol 14-alpha demethylase) (LDM) (P450-14DM) (P45014DM) Length = 503 Score = 65.1 bits (157), Expect = 4e-11 Identities = 31/66 (46%), Positives = 45/66 (68%), Gaps = 1/66 (1%) Frame = -3 Query: 310 FSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVSP-FPENDWNAMVVGIKGEVM 134 F+Y+ FG GRH C+GE FAY+QIK IW+ +LR +EF+L+ FP ++ M+ + V Sbjct: 437 FAYVPFGAGRHRCIGENFAYVQIKTIWSTMLRLYEFDLIDGYFPTVNYTTMIHTPENPV- 495 Query: 133 VNYKRR 116 + YKRR Sbjct: 496 IRYKRR 501
>CP51A_BOVIN (Q4PJW3) Cytochrome P450 51A1 (EC 1.14.13.70) (CYPLI) (P450LI)| (Sterol 14-alpha demethylase) (Lanosterol 14-alpha demethylase) (LDM) (P450-14DM) (P45014DM) Length = 502 Score = 64.3 bits (155), Expect = 7e-11 Identities = 30/66 (45%), Positives = 45/66 (68%), Gaps = 1/66 (1%) Frame = -3 Query: 310 FSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVSP-FPENDWNAMVVGIKGEVM 134 F+Y+ FG GRH C+GE FAY+QIK IW+ +LR +EF+L+ FP ++ M + + + Sbjct: 436 FAYVPFGAGRHRCIGENFAYVQIKTIWSTMLRLYEFDLIDGYFPTVNYTTM-IHTPEKPI 494 Query: 133 VNYKRR 116 + YKRR Sbjct: 495 IRYKRR 500
>CP51_USTMA (P49602) Cytochrome P450 51 (EC 1.14.13.70) (CYPLI) (P450-LIA1)| (Sterol 14-alpha demethylase) (Lanosterol 14-alpha demethylase) (P450-14DM) Length = 561 Score = 57.0 bits (136), Expect = 1e-08 Identities = 26/50 (52%), Positives = 34/50 (68%) Frame = -3 Query: 304 YISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVSPFPENDWNAMVV 155 Y+ FG GRH C+GE FAYLQI I +R F++ L S FP+ D+ +MVV Sbjct: 491 YLPFGAGRHRCIGEQFAYLQIGVILATFVRIFKWHLDSKFPDPDYQSMVV 540
>CP51_SCHPO (Q09736) Probable cytochrome P450 51 (EC 1.14.13.70) (CYPLI)| (P450-LIA1) (Sterol 14-alpha demethylase) (Lanosterol 14-alpha demethylase) (P450-14DM) Length = 495 Score = 54.7 bits (130), Expect = 6e-08 Identities = 24/66 (36%), Positives = 39/66 (59%) Frame = -3 Query: 313 AFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVSPFPENDWNAMVVGIKGEVM 134 A Y+ FG GRH C+GE FAY+ + I + + ++ + L+ P D+++MV G V Sbjct: 429 ASPYLPFGAGRHRCIGEQFAYMHLSTIISKFVHDYTWTLIGKVPNVDYSSMVALPLGPVK 488 Query: 133 VNYKRR 116 + +KRR Sbjct: 489 IAWKRR 494
>CP51_CUNEL (Q9UVC3) Cytochrome P450 51 (EC 1.14.13.70) (CYPLI) (P450-LIA1)| (Sterol 14-alpha demethylase) (Lanosterol 14-alpha demethylase) (P450-14DM) Length = 512 Score = 53.5 bits (127), Expect = 1e-07 Identities = 25/65 (38%), Positives = 40/65 (61%), Gaps = 1/65 (1%) Frame = -3 Query: 304 YISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFEL-VSPFPENDWNAMVVGIKGEVMVN 128 ++ FG GRH C+GE F YLQ+K + + +R F+F+L P++D+ +MVV + V Sbjct: 448 FLPFGAGRHRCIGEQFGYLQLKTVISTFIRTFDFDLDGKSVPKSDYTSMVVVPEHTAKVR 507 Query: 127 YKRRK 113 Y R+ Sbjct: 508 YTWRE 512
>CP51_CANTR (P14263) Cytochrome P450 51 (EC 1.14.13.70) (CYPLI) (P450-LIA1)| (Sterol 14-alpha demethylase) (Lanosterol 14-alpha demethylase) (P450-14DM) Length = 528 Score = 49.3 bits (116), Expect = 2e-06 Identities = 23/50 (46%), Positives = 33/50 (66%), Gaps = 1/50 (2%) Frame = -3 Query: 304 YISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFEL-VSPFPENDWNAMV 158 Y+ FGGGRH C+GE FAY+Q+ I T + NF++ L P+ D+ +MV Sbjct: 460 YLPFGGGRHRCIGEQFAYVQLGTILTTYIYNFKWRLNGDKVPDVDYQSMV 509
>CP51_CANAL (P10613) Cytochrome P450 51 (EC 1.14.13.70) (CYPLI) (P450-LIA1)| (Sterol 14-alpha demethylase) (Lanosterol 14-alpha demethylase) (P450-14DM) Length = 528 Score = 47.8 bits (112), Expect = 7e-06 Identities = 22/51 (43%), Positives = 33/51 (64%), Gaps = 1/51 (1%) Frame = -3 Query: 304 YISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVS-PFPENDWNAMVV 155 Y+ FGGGRH C+GE FAY+Q+ I T + N + + P+ D+++MVV Sbjct: 460 YLPFGGGRHRCIGEQFAYVQLGTILTTFVYNLRWTIDGYKVPDPDYSSMVV 510
>CP136_MYCTU (P95099) Putative cytochrome P450 136 (EC 1.14.-.-)| Length = 492 Score = 47.4 bits (111), Expect = 9e-06 Identities = 29/77 (37%), Positives = 41/77 (53%), Gaps = 2/77 (2%) Frame = -3 Query: 355 DRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVSP--FP 182 +RF R E K +++ FGGG H C+G F L+IK I LLR + EL P P Sbjct: 413 ERFTEPRNEHK-RHRYAFTPFGGGVHKCIGMVFDQLEIKTILHRLLRRYRLELSRPDYQP 471 Query: 181 ENDWNAMVVGIKGEVMV 131 D++AM + + G +V Sbjct: 472 RWDYSAMPIPMDGMPIV 488
>CP51_ASHGO (Q759W0) Cytochrome P450 51 (EC 1.14.13.70) (CYPLI) (P450-LIA1)| (Sterol 14-alpha demethylase) (Lanosterol 14-alpha demethylase) (P450-14DM) Length = 529 Score = 47.0 bits (110), Expect = 1e-05 Identities = 27/86 (31%), Positives = 46/86 (53%), Gaps = 9/86 (10%) Frame = -3 Query: 346 AAGREEDKVAGAFS------YISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFEL---V 194 + G + D GA S Y+ FGGGRH C+GE FAY+Q+ I++ ++R+ ++ + Sbjct: 438 STGEKVDYGFGAISKGVSSPYLPFGGGRHRCIGEGFAYMQLGTIFSVVVRSMKWHFPADM 497 Query: 193 SPFPENDWNAMVVGIKGEVMVNYKRR 116 P D+ +MV + ++RR Sbjct: 498 KGVPNPDFTSMVTLPSEPCRIAWERR 523
>CP51_YEAST (P10614) Cytochrome P450 51 (EC 1.14.13.70) (CYPLI) (P450-LIA1)| (Sterol 14-alpha demethylase) (Lanosterol 14-alpha demethylase) (P450-14DM) Length = 530 Score = 47.0 bits (110), Expect = 1e-05 Identities = 27/86 (31%), Positives = 43/86 (50%), Gaps = 8/86 (9%) Frame = -3 Query: 349 FAAGREEDKVAGAFS------YISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELV-- 194 ++ G E D GA S Y+ FGGGRH C+GE FAY Q+ + + +R ++ Sbjct: 439 YSVGEEVDYGFGAISKGVSSPYLPFGGGRHRCIGEHFAYCQLGVLMSIFIRTLKWHYPEG 498 Query: 193 SPFPENDWNAMVVGIKGEVMVNYKRR 116 P D+ +MV G + +++R Sbjct: 499 KTVPPPDFTSMVTLPTGPAKIIWEKR 524
>CP51_PENIT (Q12664) Cytochrome P450 51 (EC 1.14.13.70) (CYPLI) (P450-LIA1)| (Sterol 14-alpha demethylase) (Eburicol 14-alpha-demethylase) (P450-14DM) Length = 515 Score = 46.6 bits (109), Expect = 2e-05 Identities = 21/51 (41%), Positives = 32/51 (62%), Gaps = 3/51 (5%) Frame = -3 Query: 304 YISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEF---ELVSPFPENDWNAM 161 Y+ FG GRH C+GE FAYL ++ I L+R F F E + P+ D++++ Sbjct: 449 YLPFGAGRHRCIGEKFAYLNLEVIVATLVREFRFFNPEGMEGVPDTDYSSL 499
>CP26C_HUMAN (Q6V0L0) Cytochrome P450 26C1 (EC 1.14.-.-)| Length = 522 Score = 45.8 bits (107), Expect = 3e-05 Identities = 24/60 (40%), Positives = 35/60 (58%), Gaps = 2/60 (3%) Frame = -3 Query: 355 DRFAAGREEDKVAGA-FSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVSP-FP 182 +RF A RE+ + A + F YI FGGG CLG+ A ++ + L+R +EL +P FP Sbjct: 431 ERFGAAREDSRGASSRFHYIPFGGGARSCLGQELAQAVLQLLAVELVRTARWELATPAFP 490
>CP6G2_DROME (Q9V675) Probable cytochrome P450 6g2 (EC 1.14.-.-) (CYPVIG2)| Length = 519 Score = 45.1 bits (105), Expect = 4e-05 Identities = 28/80 (35%), Positives = 38/80 (47%), Gaps = 3/80 (3%) Frame = -3 Query: 334 EEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVSPFPEN---DWNA 164 E K+ ++Y+ FG G HGC+GE F YLQ K +LLRN P D A Sbjct: 440 ENRKLHTPYTYMPFGLGPHGCIGERFGYLQAKVGLVNLLRNHMITTSERTPHRMQLDPKA 499 Query: 163 MVVGIKGEVMVNYKRRKLVV 104 ++ KG + + R L V Sbjct: 500 IITQAKGGIHLRLVRDALGV 519
>CP51_CANGA (P50859) Cytochrome P450 51 (EC 1.14.13.70) (CYPLI) (P450-LIA1)| (Sterol 14-alpha-demethylase) (Lanosterol 14-alpha demethylase) (P450-14DM) Length = 533 Score = 45.1 bits (105), Expect = 4e-05 Identities = 27/86 (31%), Positives = 43/86 (50%), Gaps = 9/86 (10%) Frame = -3 Query: 346 AAGREEDKVAGAFS------YISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVS-- 191 A G E D GA S Y+ FGGGRH C+GE FAY Q+ + + +R ++ + Sbjct: 442 AGGDEVDYGFGAISKGVSSPYLPFGGGRHRCIGELFAYCQLGVLMSIFIRTMKWRYPTEG 501 Query: 190 -PFPENDWNAMVVGIKGEVMVNYKRR 116 P +D+ +MV + +++R Sbjct: 502 ETVPPSDFTSMVTLPTAPAKIYWEKR 527
>CP26B_HUMAN (Q9NR63) Cytochrome P450 26B1 (EC 1.14.-.-) (P450 26A2) (P450| retinoic acid-inactivating 2) (P450RAI-2) (Retinoic-acid metabolizing cytochrome) Length = 512 Score = 44.7 bits (104), Expect = 6e-05 Identities = 24/55 (43%), Positives = 30/55 (54%) Frame = -3 Query: 355 DRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVS 191 DRF+ R EDK G F Y+ FGGG CLG+ A L +K + L FEL + Sbjct: 415 DRFSQARSEDK-DGRFHYLPFGGGVRTCLGKHLAKLFLKVLAVELASTSRFELAT 468
>CP4E2_DROME (Q27606) Cytochrome P450 4e2 (EC 1.14.-.-) (CYPIVE2)| Length = 526 Score = 44.3 bits (103), Expect = 7e-05 Identities = 19/49 (38%), Positives = 29/49 (59%) Frame = -3 Query: 352 RFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFE 206 +F R E + G F Y+ F G C+G+ FA L+IK + + ++RNFE Sbjct: 418 KFRPERFELEKPGPFEYVPFSAGPRNCIGQKFALLEIKTVVSKIIRNFE 466
>CP4E1_DROME (Q9V4T5) Probable cytochrome P450 4e1 (EC 1.14.-.-) (CYPIVE1)| Length = 531 Score = 43.9 bits (102), Expect = 1e-04 Identities = 18/49 (36%), Positives = 29/49 (59%) Frame = -3 Query: 352 RFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFE 206 +F R + + G F Y+ F G C+G+ FA L+IK + + ++RNFE Sbjct: 418 KFQPERFDREKPGPFEYVPFSAGPRNCIGQKFALLEIKTVVSKIIRNFE 466
>CP4E5_DROMT (O44221) Cytochrome P450 4e5, mitochondrial precursor (EC 1.14.-.-)| (CYPIVE5) Length = 522 Score = 43.5 bits (101), Expect = 1e-04 Identities = 19/49 (38%), Positives = 28/49 (57%) Frame = -3 Query: 352 RFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFE 206 RF R E + G F Y+ F G C+G+ FA L++K + + L+R FE Sbjct: 417 RFYPERFEKQKPGPFEYVPFSAGPRNCIGQKFALLELKTVISKLVRTFE 465
>C6A13_DROME (Q9V4U9) Probable cytochrome P450 6a13 (EC 1.14.-.-) (CYPVIA13)| Length = 493 Score = 43.5 bits (101), Expect = 1e-04 Identities = 20/44 (45%), Positives = 27/44 (61%) Frame = -3 Query: 334 EEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEF 203 EE K F+Y+ FG G C+GE F LQ+K +LLR+F+F Sbjct: 415 EEIKARHPFAYLPFGEGPRNCIGERFGKLQVKVGLVYLLRDFKF 458
>CP4D2_DROME (Q27589) Cytochrome P450 4d2 (EC 1.14.-.-) (CYPIVD2)| Length = 501 Score = 43.1 bits (100), Expect = 2e-04 Identities = 19/56 (33%), Positives = 32/56 (57%) Frame = -3 Query: 310 FSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVSPFPENDWNAMVVGIKG 143 ++YI F G C+G+ FA L++K+ + LLR+FE + P P + N ++ G Sbjct: 437 YAYIPFSAGPRNCIGQKFAMLEMKSTVSKLLRHFELLPLGPEPRHSMNIVLRSANG 492
>C4D10_DROMT (O18596) Cytochrome P450 4d10 (EC 1.14.-.-) (CYPIVD10)| Length = 513 Score = 43.1 bits (100), Expect = 2e-04 Identities = 23/66 (34%), Positives = 37/66 (56%), Gaps = 2/66 (3%) Frame = -3 Query: 307 SYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVSPFPEND--WNAMVVGIKGEVM 134 +YI F G C+G+ FA L+IKAI ++LR++E E V E+ +++ K +M Sbjct: 446 AYIPFSAGPRNCIGQKFAMLEIKAIAANVLRHYEIEFVGNAEESPVLIAELILRTKDPLM 505 Query: 133 VNYKRR 116 K+R Sbjct: 506 FKLKKR 511
>CP26B_BRARE (Q6EIG3) Cytochrome P450 26B1 (EC 1.14.-.-) (Cyp26B1)| (Retinoic-acid metabolizing cytochrome) Length = 511 Score = 43.1 bits (100), Expect = 2e-04 Identities = 23/53 (43%), Positives = 29/53 (54%) Frame = -3 Query: 355 DRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFEL 197 DRF+ R ED+ G F Y+ FGGG CLG+ A L +K + L FEL Sbjct: 414 DRFSPERSEDR-EGRFHYLPFGGGVRSCLGKQLATLFLKLLAVELAGGSRFEL 465
>THAS_PIG (P47787) Thromboxane-A synthase (EC 5.3.99.5) (TXA synthase) (TXS)| Length = 534 Score = 42.7 bits (99), Expect = 2e-04 Identities = 21/52 (40%), Positives = 28/52 (53%) Frame = -3 Query: 355 DRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFE 200 +RF A E ++ F+Y+ FG G CLG L+IK H+LR F FE Sbjct: 455 ERFTA--EAQRLQQPFTYLPFGAGPRSCLGVQLGLLEIKLTLLHILRKFRFE 504
>CP26A_CHICK (Q9PUB4) Cytochrome P450 26A1 (EC 1.14.-.-) (Retinoic acid| degrading enzyme CYP26) Length = 492 Score = 42.7 bits (99), Expect = 2e-04 Identities = 24/83 (28%), Positives = 43/83 (51%), Gaps = 10/83 (12%) Frame = -3 Query: 355 DRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVS----- 191 DRF + ED + FS+I FGGG C+G+ FA + +K L R+ +++L++ Sbjct: 412 DRFMSPSPED--SSRFSFIPFGGGLRSCVGKEFAKVLLKIFTVELARSCDWQLLNGPPTM 469 Query: 190 -----PFPENDWNAMVVGIKGEV 137 +P ++ A +G G++ Sbjct: 470 KTGPIVYPVDNLPAKFIGFSGQI 492
>CP26A_MOUSE (O55127) Cytochrome P450 26A1 (EC 1.14.-.-) (Retinoic| acid-metabolizing cytochrome) (P450RAI) (Retinoic acid 4-hydroxylase) Length = 497 Score = 42.7 bits (99), Expect = 2e-04 Identities = 22/58 (37%), Positives = 33/58 (56%) Frame = -3 Query: 355 DRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVSPFP 182 DRF ED A FS+I FGGG C+G+ FA + +K L R+ +++L++ P Sbjct: 417 DRFIVPHPED--ASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPP 472
>CP26A_HUMAN (O43174) Cytochrome P450 26A1 (EC 1.14.-.-) (Retinoic| acid-metabolizing cytochrome) (P450 retinoic acid-inactivating 1) (P450RAI) (hP450RAI) (Retinoic acid 4-hydroxylase) Length = 497 Score = 42.4 bits (98), Expect = 3e-04 Identities = 22/58 (37%), Positives = 33/58 (56%) Frame = -3 Query: 355 DRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVSPFP 182 DRF ED A FS+I FGGG C+G+ FA + +K L R+ +++L++ P Sbjct: 417 DRFMLPHPED--ASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPP 472
>CP4D1_DROSI (O16805) Cytochrome P450 4d1 (EC 1.14.-.-) (CYPIVD1)| Length = 512 Score = 42.0 bits (97), Expect = 4e-04 Identities = 18/44 (40%), Positives = 28/44 (63%) Frame = -3 Query: 310 FSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVSPFPE 179 ++YI F G C+G+ FA L+IKAI ++LR++E + V E Sbjct: 444 YAYIPFSAGPRNCIGQKFAMLEIKAIVANVLRHYEVDFVGDSSE 487
>CP4D1_DROME (P33269) Cytochrome P450 4d1 (EC 1.14.-.-) (CYPIVD1)| Length = 512 Score = 42.0 bits (97), Expect = 4e-04 Identities = 18/44 (40%), Positives = 28/44 (63%) Frame = -3 Query: 310 FSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVSPFPE 179 ++YI F G C+G+ FA L+IKAI ++LR++E + V E Sbjct: 444 YAYIPFSAGPRNCIGQKFAMLEIKAIVANVLRHYEVDFVGDSSE 487
>CP311_DROME (Q9VYQ7) Probable cytochrome P450 311a1 (EC 1.14.-.-) (CYPCCCXIA1)| Length = 483 Score = 42.0 bits (97), Expect = 4e-04 Identities = 18/39 (46%), Positives = 25/39 (64%) Frame = -3 Query: 313 AFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFEL 197 AFSYI F GG H C+G ++ L +K + L+R F+ EL Sbjct: 417 AFSYIPFSGGPHVCIGRRYSLLLMKLLTARLVREFQMEL 455
>CP312_DROME (Q9VVN6) Probable cytochrome P450 312a1 (EC 1.14.-.-) (CYPCCCXIIA1)| Length = 510 Score = 41.6 bits (96), Expect = 5e-04 Identities = 22/52 (42%), Positives = 29/52 (55%) Frame = -3 Query: 355 DRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFE 200 DR+A G E A F I F G C+G+ +A + +K + HLLRNF FE Sbjct: 430 DRWAIGAEPKIEATTF--IPFMAGARSCMGQRYAMVMLKMVLAHLLRNFLFE 479
>CP46A_MOUSE (Q9WVK8) Cytochrome p450 46A1 (EC 1.14.13.98) (Cholesterol| 24-hydroxylase) (CH24H) Length = 500 Score = 41.6 bits (96), Expect = 5e-04 Identities = 19/54 (35%), Positives = 29/54 (53%) Frame = -3 Query: 355 DRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELV 194 DRF G + + F+Y F G C+G+ FA +++K + LL+ EF LV Sbjct: 414 DRFGPGAPKPR----FTYFPFSLGHRSCIGQQFAQMEVKVVMAKLLQRIEFRLV 463
>CP46A_HUMAN (Q9Y6A2) Cytochrome p450 46A1 (EC 1.14.13.98) (Cholesterol| 24-hydroxylase) (CH24H) Length = 500 Score = 41.6 bits (96), Expect = 5e-04 Identities = 19/54 (35%), Positives = 29/54 (53%) Frame = -3 Query: 355 DRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELV 194 DRF G + + F+Y F G C+G+ FA +++K + LL+ EF LV Sbjct: 414 DRFGPGAPKPR----FTYFPFSLGHRSCIGQQFAQMEVKVVMAKLLQRLEFRLV 463
>CP6K1_BLAGE (Q964R0) Cytochrome P450 6k1 (EC 1.14.-.-) (CYPVIK1)| Length = 524 Score = 41.2 bits (95), Expect = 6e-04 Identities = 18/50 (36%), Positives = 28/50 (56%) Frame = -3 Query: 355 DRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFE 206 +RF+ E + A++Y+ FG G H C+G F Y+ +K H+L FE Sbjct: 439 ERFS--EENKRQRKAYTYLPFGEGPHNCIGLRFGYMAVKTALVHMLAEFE 486
>CP6J1_BLAGE (Q964R1) Cytochrome P450 6j1 (EC 1.14.-.-) (CYPVIJ1)| Length = 501 Score = 40.4 bits (93), Expect = 0.001 Identities = 20/44 (45%), Positives = 26/44 (59%) Frame = -3 Query: 310 FSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVSPFPE 179 F+Y+ FG G C+G F +Q+KA H+L NFE VSP E Sbjct: 432 FAYMPFGEGPRNCIGMRFGSMQVKAALIHILSNFE---VSPCKE 472
>CP51_UNCNE (O14442) Cytochrome P450 51 (EC 1.14.13.70) (CYPLI) (P450-LIA1)| (Sterol 14-alpha demethylase) (Eburicol 14-alpha-demethylase) (P450-14DM) Length = 524 Score = 40.4 bits (93), Expect = 0.001 Identities = 17/34 (50%), Positives = 22/34 (64%) Frame = -3 Query: 304 YISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEF 203 Y+ FG GRH C+GE FA LQ+ I ++R F F Sbjct: 459 YLPFGAGRHRCIGEQFATLQLVTIMATMVRFFRF 492
>CP26A_XENLA (O93323) Cytochrome P450 26A1 (EC 1.14.-.-) (Retinoic acid| degrading enzyme CYP26) (xCYP26) (Retinoic acid-converting enzyme) (RACE) Length = 492 Score = 40.0 bits (92), Expect = 0.001 Identities = 21/58 (36%), Positives = 31/58 (53%) Frame = -3 Query: 355 DRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVSPFP 182 DRF D + F +I FGGG C+G+ FA + +K L RN ++EL++ P Sbjct: 412 DRFLTPLPRD--SSRFGFIPFGGGVRCCIGKEFAKILLKVFVVELCRNCDWELLNGSP 467
>C97B2_SOYBN (O48921) Cytochrome P450 97B2 (EC 1.14.-.-)| Length = 576 Score = 40.0 bits (92), Expect = 0.001 Identities = 17/44 (38%), Positives = 28/44 (63%) Frame = -3 Query: 328 DKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFEL 197 ++V F+++ FGGG C+G+ FA ++ T LL+NF+ EL Sbjct: 501 NEVISDFAFLPFGGGPRKCVGDQFALMESTVALTMLLQNFDVEL 544
>C13A8_CAEEL (Q27516) Putative cytochrome P450 CYP13A8 (EC 1.14.-.-)| Length = 509 Score = 39.7 bits (91), Expect = 0.002 Identities = 18/52 (34%), Positives = 29/52 (55%) Frame = -3 Query: 355 DRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFE 200 + F R + + +Y+SFG G CLG FA L+ K + +H+L+ + FE Sbjct: 428 EEFKPERWDSPLTPQQAYLSFGAGPRVCLGMRFALLEQKGLLSHILKKYTFE 479
>CP120_SYNY3 (Q59990) Putative cytochrome P450 120 (EC 1.14.-.-)| Length = 444 Score = 39.7 bits (91), Expect = 0.002 Identities = 16/39 (41%), Positives = 27/39 (69%) Frame = -3 Query: 310 FSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELV 194 F+++ FGGG CLG+ FA L++K T L++ F++ L+ Sbjct: 379 FAHVPFGGGLRECLGKEFARLEMKLFATRLIQQFDWTLL 417
>CP9E2_BLAGE (Q964T2) Cytochrome P450 9e2 (EC 1.14.-.-) (CYPIXE2)| Length = 533 Score = 39.7 bits (91), Expect = 0.002 Identities = 17/43 (39%), Positives = 24/43 (55%) Frame = -3 Query: 310 FSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVSPFP 182 F+Y+ FG G C+G FA ++ K HLL F ++VS P Sbjct: 463 FTYLPFGSGPRNCIGNRFALMESKIALVHLLCRFNLKVVSKTP 505
>CP4E3_DROME (Q9VL92) Cytochrome P450 4e3 (EC 1.14.-.-) (CYPIVE3)| Length = 526 Score = 39.7 bits (91), Expect = 0.002 Identities = 16/48 (33%), Positives = 28/48 (58%) Frame = -3 Query: 349 FAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFE 206 F R E++ F Y+ F G C+G+ FA L++K + + ++R+FE Sbjct: 418 FRPERFEEEKPAPFEYLPFSAGPRNCIGQKFALLELKTVISKVVRSFE 465
>C13AA_CAEEL (Q09653) Putative cytochrome P450 CYP13A10 (EC 1.14.-.-)| Length = 519 Score = 38.9 bits (89), Expect = 0.003 Identities = 18/44 (40%), Positives = 26/44 (59%) Frame = -3 Query: 328 DKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFEL 197 D+V YISFG G C+G AY++ K + H+LR + FE+ Sbjct: 447 DQVFQKGGYISFGLGPRQCVGMRLAYMEEKMLLAHILRKYTFEV 490
>C4AC2_DROME (Q9VMS8) Probable cytochrome P450 4ac2 (EC 1.14.-.-) (CYPIVAC2)| Length = 497 Score = 38.9 bits (89), Expect = 0.003 Identities = 19/67 (28%), Positives = 37/67 (55%), Gaps = 1/67 (1%) Frame = -3 Query: 310 FSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVSPFPENDW-NAMVVGIKGEVM 134 F+++ F G+ C+G+ FA L+IK + ++RNF+ V+ + + N +V+ K + Sbjct: 429 FAFVPFSAGQRNCIGQKFAILEIKVLLAAVIRNFKILPVTLLDDLTFENGIVLRTKQNIK 488 Query: 133 VNYKRRK 113 V R+ Sbjct: 489 VKLVHRE 495
>CP4CU_BLAGE (Q964T1) Cytochrome P450 4c21 (EC 1.14.14.1) (CYPIVC21)| Length = 501 Score = 38.9 bits (89), Expect = 0.003 Identities = 15/40 (37%), Positives = 26/40 (65%) Frame = -3 Query: 310 FSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVS 191 ++YI F G C+G+ FA L+ K + ++LLR++ F V+ Sbjct: 435 YAYIPFSAGPRNCIGQRFALLEEKVVLSYLLRHYRFRTVN 474
>CP9B2_DROME (Q9V4I1) Cytochrome P450 9b2 (EC 1.14.-.-) (CYPIXB2)| Length = 505 Score = 38.9 bits (89), Expect = 0.003 Identities = 18/52 (34%), Positives = 32/52 (61%) Frame = -3 Query: 355 DRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFE 200 DRF+ R+ D V ++Y+ FG G C+G +A +Q+K + +LL +++ E Sbjct: 424 DRFSEERKGDMVP--YTYLPFGVGPRNCIGNRYALMQVKGMLFNLLLHYKIE 473
>CP2DE_BOVIN (Q01361) Cytochrome P450 2D14 (EC 1.14.14.1) (CYPIID14) (Fragment)| Length = 487 Score = 38.5 bits (88), Expect = 0.004 Identities = 16/42 (38%), Positives = 26/42 (61%) Frame = -3 Query: 307 SYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVSPFP 182 ++I F GR CLGEP A +++ +T LL++F F + + P Sbjct: 422 AFIPFSAGRRACLGEPLARMELFLFFTSLLQHFSFSVPAGQP 463
>C13A1_CAEEL (Q27520) Putative cytochrome P450 CYP13A1 (EC 1.14.-.-)| Length = 519 Score = 38.1 bits (87), Expect = 0.005 Identities = 17/43 (39%), Positives = 24/43 (55%) Frame = -3 Query: 328 DKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFE 200 D++ YI FG G C+G AY++ K + H+LR F FE Sbjct: 447 DQIYQKSGYIPFGLGPRQCIGMRLAYMEEKILLVHILRKFTFE 489
>C4AC1_DROME (Q9VMS9) Probable cytochrome P450 4ac1 (EC 1.14.-.-) (CYPIVAC1)| Length = 509 Score = 38.1 bits (87), Expect = 0.005 Identities = 13/35 (37%), Positives = 24/35 (68%) Frame = -3 Query: 310 FSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFE 206 F+Y+ F G+ C+G+ FA L++K + ++RNF+ Sbjct: 442 FAYVPFSAGQRNCIGQKFAILEMKVLLAAVIRNFK 476
>CP39A_MOUSE (Q9JKJ9) Cytochrome P450 39A1 (EC 1.14.13.99)| (24-hydroxycholesterol 7-alpha-hydroxylase) (Oxysterol 7-alpha-hydroxylase) (mCYP39A1) Length = 470 Score = 38.1 bits (87), Expect = 0.005 Identities = 21/66 (31%), Positives = 37/66 (56%), Gaps = 3/66 (4%) Frame = -3 Query: 304 YISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVSPFPENDWNAMVVGI---KGEVM 134 +++FGGG+ C G FA L+I+ +L +E L+ P P+ + +VG+ G+ Sbjct: 405 FMAFGGGKFQCPGRWFALLEIQLCIILVLYKYECSLLDPLPKQS-SRHLVGVPQPAGKCR 463 Query: 133 VNYKRR 116 + YK+R Sbjct: 464 IEYKQR 469
>CP6T3_DROME (Q9V676) Probable cytochrome P450 6t3 (EC 1.14.-.-) (CYPVIT3)| Length = 501 Score = 38.1 bits (87), Expect = 0.005 Identities = 17/47 (36%), Positives = 24/47 (51%) Frame = -3 Query: 340 GREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFE 200 G E + +YI FG G HGC+G LQ+K H+L+ + E Sbjct: 422 GPERSRHIHPMTYIPFGAGPHGCIGSRLGVLQLKLGIVHILKQYWVE 468
>CPXN_ANASP (P29980) Probable cytochrome P450 110 (EC 1.14.-.-)| Length = 459 Score = 38.1 bits (87), Expect = 0.005 Identities = 18/43 (41%), Positives = 23/43 (53%) Frame = -3 Query: 304 YISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVSPFPEN 176 YI FGGG CLG A L+IK + +L N++ L P N Sbjct: 383 YIPFGGGSRRCLGYALALLEIKLVIATVLSNYQLALAEDKPVN 425
>CP4C3_DROME (Q9VA27) Cytochrome P450 4c3 (EC 1.14.-.-) (CYPIVC3)| Length = 535 Score = 38.1 bits (87), Expect = 0.005 Identities = 16/39 (41%), Positives = 25/39 (64%) Frame = -3 Query: 310 FSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELV 194 F+YI F G C+G+ FA L+ KA+ + +LR ++ E V Sbjct: 469 FAYIPFSAGPRNCIGQKFAILEEKAVISTVLRKYKIEAV 507
>CP2D6_PANTR (Q2XNC8) Cytochrome P450 2D6 (EC 1.14.14.1) (CYPIID6)| Length = 497 Score = 37.7 bits (86), Expect = 0.007 Identities = 15/42 (35%), Positives = 26/42 (61%) Frame = -3 Query: 307 SYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVSPFP 182 +++ F GR CLGEP A +++ +T LL++F F + + P Sbjct: 432 AFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFSVPTGQP 473
>CP2D6_PANPA (Q2XNC9) Cytochrome P450 2D6 (EC 1.14.14.1) (CYPIID6)| Length = 497 Score = 37.7 bits (86), Expect = 0.007 Identities = 15/42 (35%), Positives = 26/42 (61%) Frame = -3 Query: 307 SYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVSPFP 182 +++ F GR CLGEP A +++ +T LL++F F + + P Sbjct: 432 AFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFSVPTGQP 473
>CP2D6_HUMAN (P10635) Cytochrome P450 2D6 (EC 1.14.14.1) (CYPIID6) (P450-DB1)| (Debrisoquine 4-hydroxylase) Length = 497 Score = 37.7 bits (86), Expect = 0.007 Identities = 15/42 (35%), Positives = 26/42 (61%) Frame = -3 Query: 307 SYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVSPFP 182 +++ F GR CLGEP A +++ +T LL++F F + + P Sbjct: 432 AFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFSVPTGQP 473
>C28D2_DROME (Q9VMT6) Probable cytochrome P450 28d2 (EC 1.14.-.-) (CYPXXVIIID2)| Length = 501 Score = 37.7 bits (86), Expect = 0.007 Identities = 22/65 (33%), Positives = 35/65 (53%), Gaps = 4/65 (6%) Frame = -3 Query: 304 YISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVSPFPENDWNA----MVVGIKGEV 137 Y++FG G C G FA Q+KA +LRNFE + V+P +D + +KG + Sbjct: 436 YLAFGDGPRHCPGMRFALTQLKAALVEILRNFEIK-VNPKTRSDNQIDDTFFMATLKGGI 494 Query: 136 MVNYK 122 +++K Sbjct: 495 YLDFK 499
>CP9B1_DROME (Q9V4I0) Cytochrome P450 9b1 (EC 1.14.-.-) (CYPIXB1)| Length = 505 Score = 37.7 bits (86), Expect = 0.007 Identities = 17/64 (26%), Positives = 35/64 (54%) Frame = -3 Query: 355 DRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVSPFPEN 176 +RF+ R++D + ++Y+ FG G C+G +A +Q K + +L+ N++ E + Sbjct: 424 ERFSERRKKDLIP--YTYLPFGVGPRSCIGNRYAVMQAKGMLYNLMLNYKIEASPRTTRD 481 Query: 175 DWNA 164 W + Sbjct: 482 MWES 485
>CP9F2_DROME (Q9VG82) Probable cytochrome P450 9f2 (EC 1.14.-.-) (CYPIXF2)| Length = 516 Score = 37.7 bits (86), Expect = 0.007 Identities = 15/36 (41%), Positives = 24/36 (66%) Frame = -3 Query: 310 FSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEF 203 F+Y FG G+ C+G FA L+ KA+ +LL+++ F Sbjct: 448 FTYFPFGLGQRNCIGSRFALLEAKAVIYYLLKDYRF 483
>CP2DA_MOUSE (P24456) Cytochrome P450 2D10 (EC 1.14.14.1) (CYPIID10)| (P450-16-alpha) (P450CB) (Testosterone 16-alpha hydroxylase) Length = 504 Score = 37.4 bits (85), Expect = 0.009 Identities = 17/46 (36%), Positives = 28/46 (60%), Gaps = 2/46 (4%) Frame = -3 Query: 307 SYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVS--PFPEN 176 +++ F GR CLGEP A +++ +T LL++F F + + P P N Sbjct: 435 AFMPFSAGRRSCLGEPLARMELFLFFTCLLQHFSFSVPNGQPRPRN 480
>CP2DQ_RAT (P10634) Cytochrome P450 2D26 (EC 1.14.14.1) (CYPIID26) (P450-DB2)| (P450-CMF2) (Debrisoquine 4-hydroxylase) Length = 500 Score = 37.4 bits (85), Expect = 0.009 Identities = 15/42 (35%), Positives = 26/42 (61%) Frame = -3 Query: 307 SYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVSPFP 182 +++ F GR CLGEP A +++ +T LL+ F F +++ P Sbjct: 435 AFMPFSAGRRACLGEPLARMELFLFFTCLLQRFSFSVLAGRP 476
>CP138_MYCTU (P63717) Putative cytochrome P450 138 (EC 1.14.-.-)| Length = 441 Score = 37.4 bits (85), Expect = 0.009 Identities = 18/52 (34%), Positives = 27/52 (51%) Frame = -3 Query: 355 DRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFE 200 DRF R F++I FGGG C+G FA +++ + +LR+F E Sbjct: 361 DRFDPQRYIGSKPSPFAWIPFGGGTRRCVGAAFANMEMDVVLRTVLRHFTLE 412
>CP138_MYCBO (P63718) Putative cytochrome P450 138 (EC 1.14.-.-)| Length = 441 Score = 37.4 bits (85), Expect = 0.009 Identities = 18/52 (34%), Positives = 27/52 (51%) Frame = -3 Query: 355 DRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFE 200 DRF R F++I FGGG C+G FA +++ + +LR+F E Sbjct: 361 DRFDPQRYIGSKPSPFAWIPFGGGTRRCVGAAFANMEMDVVLRTVLRHFTLE 412
>C4D14_DROME (O46051) Probable cytochrome P450 4d14 (EC 1.14.-.-) (CYPIVD14)| Length = 507 Score = 37.0 bits (84), Expect = 0.012 Identities = 17/50 (34%), Positives = 30/50 (60%) Frame = -3 Query: 355 DRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFE 206 DRF+ R+ + F+Y F G C+G+ FA L++K+ + ++R+FE Sbjct: 429 DRFSMERKGE--ISPFAYTPFSAGPRNCIGQKFAMLEMKSTISKMVRHFE 476
>C4AE1_DROME (O46054) Cytochrome P450 4ae1 (EC 1.14.-.-) (CYPIVAE1)| Length = 496 Score = 37.0 bits (84), Expect = 0.012 Identities = 15/43 (34%), Positives = 26/43 (60%) Frame = -3 Query: 334 EEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFE 206 EE +SYI F G C+G+ FA L++K + T ++R+++ Sbjct: 423 EEAPRLSPYSYIPFSAGPRNCIGQKFALLEMKTMVTKVIRHYQ 465
>CP17A_FELCA (Q9GMC8) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 508 Score = 37.0 bits (84), Expect = 0.012 Identities = 23/83 (27%), Positives = 36/83 (43%), Gaps = 2/83 (2%) Frame = -3 Query: 355 DRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELV--SPFP 182 +RF ++ + SY+ FG G CLGE A ++ LL+ F+ E+ P Sbjct: 415 ERFLDPTRSQLISPSLSYLPFGAGPRSCLGESLARQEVFLFMAWLLQRFDLEVPDDGQLP 474 Query: 181 ENDWNAMVVGIKGEVMVNYKRRK 113 + N VV + V K R+ Sbjct: 475 HLEGNPTVVFLIAPFKVKVKVRQ 497
>CP2DI_RAT (Q64680) Cytochrome P450 2D18 (EC 1.14.14.1) (CYPIID18) (P450| 2D-29/2D-35) Length = 500 Score = 37.0 bits (84), Expect = 0.012 Identities = 17/46 (36%), Positives = 27/46 (58%), Gaps = 2/46 (4%) Frame = -3 Query: 307 SYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVS--PFPEN 176 +++ F GR CLGEP A +++ +T LL+ F F + + P P N Sbjct: 435 AFMPFSAGRRACLGEPLARMELFLFFTCLLQRFSFSVPAGQPRPSN 480
>CP2DA_RAT (P12939) Cytochrome P450 2D10 (EC 1.14.14.1) (CYPIID10) (P450-DB5)| (P450-CMF1B) (Debrisoquine 4-hydroxylase) Length = 504 Score = 36.6 bits (83), Expect = 0.016 Identities = 15/42 (35%), Positives = 26/42 (61%) Frame = -3 Query: 307 SYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVSPFP 182 +++ F GR CLGEP A +++ +T LL++F F + + P Sbjct: 435 AFMPFSAGRRACLGEPLARMELFLFFTCLLQHFSFSVPAGQP 476
>CP11A_MESAU (Q9EPT4) Cytochrome P450 11A1, mitochondrial precursor (EC| 1.14.15.6) (CYPXIA1) (P450(scc)) (Cholesterol side-chain cleavage enzyme) (Cholesterol desmolase) Length = 520 Score = 36.6 bits (83), Expect = 0.016 Identities = 19/48 (39%), Positives = 25/48 (52%) Frame = -3 Query: 334 EEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVS 191 E+ K F Y+SFG G CLG A L++ ++L NF EL S Sbjct: 438 EKSKNTTHFRYLSFGWGVRQCLGRRIAELEMTIFLINVLENFRIELQS 485
>CP310_DROME (Q9VJ71) Probable cytochrome P450 310a1 (EC 1.14.-.-) (CYPCCCXA1)| Length = 492 Score = 36.6 bits (83), Expect = 0.016 Identities = 28/81 (34%), Positives = 38/81 (46%), Gaps = 4/81 (4%) Frame = -3 Query: 340 GREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFEL----VSPFPEND 173 G+ EDK +I FG G C+G+ FA L IK LL+NF EL V + Sbjct: 407 GQCEDKTKSNV-FIGFGIGGSQCVGQNFAKLVIKVALIKLLQNFHLELDANQVKTLKVSH 465 Query: 172 WNAMVVGIKGEVMVNYKRRKL 110 A + K + V KRR++ Sbjct: 466 RPAPFIHTKDGLKVKLKRREI 486
>CP391_DROME (Q9VQD2) Probable cytochrome P450 309a1 (EC 1.14.-.-) (CYPCCCIXA1)| Length = 529 Score = 36.6 bits (83), Expect = 0.016 Identities = 17/62 (27%), Positives = 30/62 (48%) Frame = -3 Query: 304 YISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVSPFPENDWNAMVVGIKGEVMVNY 125 ++ FG G CLG L +K H+L N++ E + P + M + + G+V + Y Sbjct: 465 FLPFGDGPRICLGMRVGQLSVKTAIVHILSNYQVEQMKKVPLGADSGMGIFLNGDVELKY 524 Query: 124 KR 119 + Sbjct: 525 TK 526
>C6A18_DROME (Q9VB31) Probable cytochrome P450 6a18 (EC 1.14.-.-) (CYPVIA18)| Length = 507 Score = 36.6 bits (83), Expect = 0.016 Identities = 20/72 (27%), Positives = 37/72 (51%), Gaps = 4/72 (5%) Frame = -3 Query: 334 EEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVSPFPE----NDWN 167 EE + +++ FG G C+G F +Q + L++NF F S P+ + + Sbjct: 431 EESAKRPSVAWLPFGEGPRNCIGLRFGQMQARIGLAMLIKNFTFSPCSATPDPLTFDPHS 490 Query: 166 AMVVGIKGEVMV 131 A+++GIKG + + Sbjct: 491 AILLGIKGGIQL 502
>CP2DJ_CALJA (O18992) Cytochrome P450 2D19 (EC 1.14.14.1) (CYPIID19) (P450| CM2D-1) Length = 497 Score = 36.6 bits (83), Expect = 0.016 Identities = 15/42 (35%), Positives = 25/42 (59%) Frame = -3 Query: 307 SYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVSPFP 182 +++ F GR CLGEP A +++ +T LL+ F F + + P Sbjct: 432 AFLPFSAGRRACLGEPLARMELFLFFTCLLQRFSFSVPAGQP 473
>CP2DH_MACFA (Q29488) Cytochrome P450 2D17 (EC 1.14.14.1) (CYPIID17)| Length = 497 Score = 36.6 bits (83), Expect = 0.016 Identities = 15/42 (35%), Positives = 25/42 (59%) Frame = -3 Query: 307 SYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVSPFP 182 +++ F GR CLGEP A +++ +T LL+ F F + + P Sbjct: 432 AFLPFSAGRRACLGEPLARMELFLFFTCLLQRFSFSVPAGQP 473
>CP51_MIMIV (Q5UQI3) Probable cytochrome P450 51 (EC 1.14.13.70) (CYPLI)| (P450-LIA1) (Sterol 14-alpha demethylase) (Lanosterol 14-alpha demethylase) (P450-14DM) Length = 709 Score = 36.2 bits (82), Expect = 0.020 Identities = 19/49 (38%), Positives = 29/49 (59%) Frame = -3 Query: 352 RFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFE 206 RF A R E K +G +++G G H C G+ FA ++KA +++ NFE Sbjct: 401 RFMAPRNEPKDSG--HVMNWGKGVHECPGKQFAIYEVKAAIAYIVTNFE 447
>CP4P3_DROME (Q9V559) Probable cytochrome P450 4p3 (EC 1.14.-.-) (CYPIVP3)| Length = 515 Score = 36.2 bits (82), Expect = 0.020 Identities = 21/72 (29%), Positives = 35/72 (48%), Gaps = 6/72 (8%) Frame = -3 Query: 310 FSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVSPFPENDWNAMV------VGI 149 ++YI F G+ C+G+ FA ++K + LL+ F+ PE D +V + Sbjct: 449 YAYIPFSAGQRNCIGQKFAMQEMKTLMVALLKQFQI-----LPEIDPKTIVFQTGLTLRT 503 Query: 148 KGEVMVNYKRRK 113 K ++ V RRK Sbjct: 504 KNQIHVKLVRRK 515
>C13A2_CAEEL (Q27518) Putative cytochrome P450 CYP13A2 (EC 1.14.-.-)| Length = 515 Score = 36.2 bits (82), Expect = 0.020 Identities = 15/36 (41%), Positives = 23/36 (63%) Frame = -3 Query: 307 SYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFE 200 +Y+ FG G C+G A ++ K + THLL+N+ FE Sbjct: 449 AYLPFGLGPRQCIGMRLAIMEQKILLTHLLKNYTFE 484
>CP3AB_MOUSE (Q64459) Cytochrome P450 3A11 (EC 1.14.14.1) (CYPIIIA11)| (P-450IIIAM1) (P-450UT) Length = 504 Score = 36.2 bits (82), Expect = 0.020 Identities = 14/37 (37%), Positives = 22/37 (59%) Frame = -3 Query: 310 FSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFE 200 + Y+ FG G CLG FA + +K T +++NF F+ Sbjct: 431 YVYLPFGNGPRNCLGMRFALMNMKLALTKIMQNFSFQ 467
>CP2DS_MESAU (Q9QUJ1) Cytochrome P450 2D28 (EC 1.14.14.-) (CYPIID28)| Length = 500 Score = 36.2 bits (82), Expect = 0.020 Identities = 15/42 (35%), Positives = 25/42 (59%) Frame = -3 Query: 307 SYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVSPFP 182 +++ F GR CLGEP A +++ +T LL+ F F + + P Sbjct: 435 AFMPFSAGRRACLGEPLARMELFLFFTCLLQRFSFSVPAGQP 476
>CP2DR_MESAU (Q9QYG6) Cytochrome P450 2D27 (EC 1.14.14.-) (CYPIID27)| Length = 500 Score = 36.2 bits (82), Expect = 0.020 Identities = 15/42 (35%), Positives = 25/42 (59%) Frame = -3 Query: 307 SYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVSPFP 182 +++ F GR CLGEP A +++ +T LL+ F F + + P Sbjct: 435 AFMPFSAGRRACLGEPLARMELFLFFTCLLQRFSFSVPAGQP 476
>CP2DK_MESAU (Q9QYG5) Cytochrome P450 2D20 (EC 1.14.14.-) (CYPIID20)| Length = 500 Score = 36.2 bits (82), Expect = 0.020 Identities = 15/42 (35%), Positives = 25/42 (59%) Frame = -3 Query: 307 SYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVSPFP 182 +++ F GR CLGEP A +++ +T LL+ F F + + P Sbjct: 435 AFMPFSAGRRACLGEPLARMELFLFFTCLLQRFSFSVPAGQP 476
>CP2D4_RAT (P13108) Cytochrome P450 2D4 (EC 1.14.14.1) (CYPIID4) (P450-DB4)| (P450-CMF3) (Debrisoquine 4-hydroxylase) Length = 500 Score = 36.2 bits (82), Expect = 0.020 Identities = 15/42 (35%), Positives = 25/42 (59%) Frame = -3 Query: 307 SYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVSPFP 182 +++ F GR CLGEP A +++ +T LL+ F F + + P Sbjct: 435 AFMPFSAGRRACLGEPLARMELFLFFTCLLQRFSFSVPTGQP 476
>CP2D3_RAT (P12938) Cytochrome P450 2D3 (EC 1.14.14.1) (CYPIID3) (P450-DB3)| (Debrisoquine 4-hydroxylase) Length = 500 Score = 36.2 bits (82), Expect = 0.020 Identities = 15/42 (35%), Positives = 25/42 (59%) Frame = -3 Query: 307 SYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVSPFP 182 +++ F GR CLGEP A +++ +T LL+ F F + + P Sbjct: 435 AFMPFSAGRRACLGEPLARMELFLFFTCLLQRFSFSVPTGQP 476
>CP4C1_BLADI (P29981) Cytochrome P450 4C1 (EC 1.14.14.1) (CYPIVC1)| Length = 511 Score = 36.2 bits (82), Expect = 0.020 Identities = 13/35 (37%), Positives = 23/35 (65%) Frame = -3 Query: 310 FSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFE 206 ++Y+ F G C+G+ FA L+ K + + +LRNF+ Sbjct: 440 YAYVPFSAGPRNCIGQKFATLEEKTVLSSILRNFK 474
>CP3AS_BOVIN (P79102) Cytochrome P450 3A28 (EC 1.14.14.1) (CYPIIIA28)| Length = 507 Score = 35.8 bits (81), Expect = 0.027 Identities = 17/52 (32%), Positives = 27/52 (51%) Frame = -3 Query: 355 DRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFE 200 +RF+ ++ + Y+ FG G CLG FA + IK +L+NF F+ Sbjct: 417 ERFSKNNKDS--INPYVYLPFGTGPRNCLGMRFAIMNIKLALVRILQNFSFK 466
>C4AC3_DROME (Q9VMS7) Probable cytochrome P450 4ac3 (EC 1.14.-.-) (CYPIVAC3)| Length = 509 Score = 35.8 bits (81), Expect = 0.027 Identities = 16/66 (24%), Positives = 35/66 (53%), Gaps = 1/66 (1%) Frame = -3 Query: 310 FSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVSPFPENDW-NAMVVGIKGEVM 134 F+++ F G C+G+ F L+IK + ++RNF+ + + + N +V+ + + Sbjct: 442 FAFVPFSAGPRNCIGQKFGVLEIKVLLAAVIRNFKLLPATQLEDLTFENGIVLRTQQNIK 501 Query: 133 VNYKRR 116 V ++ R Sbjct: 502 VKFEAR 507
>CP3A6_RABIT (P11707) Cytochrome P450 3A6 (EC 1.14.14.1) (CYPIIIA6) (P450-3C)| Length = 501 Score = 35.8 bits (81), Expect = 0.027 Identities = 16/38 (42%), Positives = 21/38 (55%) Frame = -3 Query: 310 FSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFEL 197 + Y FG G CLG FA + IK L++NF F+L Sbjct: 428 YIYHPFGAGPRNCLGMRFALMNIKLALVRLMQNFSFKL 465
>C4D20_DROME (Q9W011) Probable cytochrome P450 4d20 (EC 1.14.-.-) (CYPIVD20)| Length = 510 Score = 35.8 bits (81), Expect = 0.027 Identities = 16/50 (32%), Positives = 29/50 (58%) Frame = -3 Query: 355 DRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFE 206 +RF +E+ F+Y+ F G C+G+ FA L++K + + +LR +E Sbjct: 430 ERFLEDQEQGH--NTFAYVPFSAGPKNCIGQKFAVLEMKVLISKVLRFYE 477
>THAS_HUMAN (P24557) Thromboxane-A synthase (EC 5.3.99.5) (TXA synthase) (TXS)| Length = 533 Score = 35.8 bits (81), Expect = 0.027 Identities = 14/37 (37%), Positives = 20/37 (54%) Frame = -3 Query: 310 FSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFE 200 F+Y+ FG G CLG L++K H+L F F+ Sbjct: 467 FTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQ 503
>CP3A2_RAT (P05183) Cytochrome P450 3A2 (EC 1.14.14.1) (CYPIIIA2) (P450-PCN2)| (P450/6-beta-A) (Testosterone 6-beta-hydroxylase) Length = 504 Score = 35.8 bits (81), Expect = 0.027 Identities = 14/37 (37%), Positives = 22/37 (59%) Frame = -3 Query: 310 FSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFE 200 + Y+ FG G C+G FA + +K T +L+NF F+ Sbjct: 431 YVYLPFGNGPRNCIGMRFALMNMKLALTKVLQNFSFQ 467
>CP3A1_RAT (P04800) Cytochrome P450 3A1 (EC 1.14.14.1) (CYPIIIA1) (P450-PCN1)| Length = 504 Score = 35.8 bits (81), Expect = 0.027 Identities = 14/37 (37%), Positives = 22/37 (59%) Frame = -3 Query: 310 FSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFE 200 + Y+ FG G C+G FA + +K T +L+NF F+ Sbjct: 431 YVYLPFGNGPRNCIGMRFALMNMKLALTKVLQNFSFQ 467
>CP2D1_RAT (P10633) Cytochrome P450 2D1 (EC 1.14.14.1) (CYPIID1) (P450-DB1)| (P450-CMF1A) (P450-UT-7) (Debrisoquine 4-hydroxylase) Length = 504 Score = 35.8 bits (81), Expect = 0.027 Identities = 14/37 (37%), Positives = 23/37 (62%) Frame = -3 Query: 307 SYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFEL 197 +++ F GR CLGEP A +++ +T LL+ F F + Sbjct: 435 AFMPFSAGRRACLGEPLARMELFLFFTCLLQRFSFSV 471
>CP2DP_PIG (O46658) Cytochrome P450 2D25 (EC 1.14.14.-) (CYPIID25) (Vitamin| D(3) 25-hydroxylase) Length = 499 Score = 35.8 bits (81), Expect = 0.027 Identities = 15/42 (35%), Positives = 25/42 (59%) Frame = -3 Query: 307 SYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVSPFP 182 +++ F GR CLGEP A +++ +T LL+ F F + + P Sbjct: 434 AFMPFSAGRRSCLGEPLARMELFLFFTTLLQAFSFSVPTGQP 475
>C4D21_DROME (Q9VLZ7) Probable cytochrome P450 4d21 (EC 1.14.-.-) (CYPIVD21)| Length = 511 Score = 35.8 bits (81), Expect = 0.027 Identities = 14/34 (41%), Positives = 24/34 (70%) Frame = -3 Query: 307 SYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFE 206 +YI F G C+G+ FA LQ+KA+ + ++R++E Sbjct: 445 AYIPFSSGPKNCIGQKFANLQMKALISKVIRHYE 478
>CP6T1_DROME (Q9VRI9) Probable cytochrome P450 6t1 (EC 1.14.-.-) (CYPVIT1)| Length = 529 Score = 35.8 bits (81), Expect = 0.027 Identities = 18/53 (33%), Positives = 29/53 (54%) Frame = -3 Query: 355 DRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFEL 197 +RF+A E+ + +Y+ FG G GC+G L+IK H+L +F E+ Sbjct: 447 ERFSA--EQRQQHHPMTYLPFGAGPRGCIGTLLGQLEIKVGLLHILNHFRVEV 497
>CP2DQ_MOUSE (Q8CIM7) Cytochrome P450 2D26 (EC 1.14.14.1) (CYPIID26)| Length = 500 Score = 35.8 bits (81), Expect = 0.027 Identities = 14/37 (37%), Positives = 23/37 (62%) Frame = -3 Query: 307 SYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFEL 197 +++ F GR CLGEP A +++ +T LL+ F F + Sbjct: 435 AFMPFSAGRRSCLGEPLARMELFLFFTCLLQRFSFSV 471
>CP4S3_DROME (Q9VXY0) Probable cytochrome P450 4s3 (EC 1.14.-.-) (CYPIVS3)| Length = 495 Score = 35.4 bits (80), Expect = 0.035 Identities = 17/51 (33%), Positives = 27/51 (52%) Frame = -3 Query: 355 DRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEF 203 DRF +K F++ +F G C+G+ FA L++K LLR++ F Sbjct: 412 DRFLVN---EKQMHPFAFAAFSAGPRNCIGQKFAMLELKTSLAMLLRSYRF 459
>C12A2_MUSDO (O18635) Cytochrome P450 CYP12A2 (EC 1.14.-.-) (CYPXIIA2)| Length = 537 Score = 35.4 bits (80), Expect = 0.035 Identities = 16/59 (27%), Positives = 31/59 (52%) Frame = -3 Query: 325 KVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVSPFPENDWNAMVVGI 149 K + F Y+ FG G C+G A ++++ L+RNF E P +N + ++++ + Sbjct: 466 KASSPFVYLPFGFGSRSCIGRRIAEMELELGIARLIRNFHVEFNYP-TDNAFKSLLISV 523
>CP17A_PAPHU (Q9GLD2) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 508 Score = 35.4 bits (80), Expect = 0.035 Identities = 23/83 (27%), Positives = 37/83 (44%), Gaps = 2/83 (2%) Frame = -3 Query: 355 DRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELV--SPFP 182 +RF ++ + SY+ FG G C+GE A ++ I LL+ F+ E+ P Sbjct: 415 ERFLNPAGTQLISPSLSYLPFGAGPRSCIGEILARQELFLIMAWLLQRFDLEVPDDGQLP 474 Query: 181 ENDWNAMVVGIKGEVMVNYKRRK 113 + N VV + V K R+ Sbjct: 475 SLEGNPKVVFLIDSFKVKIKVRQ 497
>CP17A_PAPCY (Q8HYN0) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 508 Score = 35.4 bits (80), Expect = 0.035 Identities = 23/83 (27%), Positives = 37/83 (44%), Gaps = 2/83 (2%) Frame = -3 Query: 355 DRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELV--SPFP 182 +RF ++ + SY+ FG G C+GE A ++ I LL+ F+ E+ P Sbjct: 415 ERFLNPAGTQLISPSLSYLPFGAGPRSCIGEILARQELFLIMAWLLQRFDLEVPDDGQLP 474 Query: 181 ENDWNAMVVGIKGEVMVNYKRRK 113 + N VV + V K R+ Sbjct: 475 SLEGNPKVVFLIDSFKVKIKVRQ 497
>CP17A_MACMU (Q8HYM9) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 508 Score = 35.4 bits (80), Expect = 0.035 Identities = 23/83 (27%), Positives = 37/83 (44%), Gaps = 2/83 (2%) Frame = -3 Query: 355 DRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELV--SPFP 182 +RF ++ + SY+ FG G C+GE A ++ I LL+ F+ E+ P Sbjct: 415 ERFLNPAGTQLISPSLSYLPFGAGPRSCIGEILARQELFLIMAWLLQRFDLEVPDDGQLP 474 Query: 181 ENDWNAMVVGIKGEVMVNYKRRK 113 + N VV + V K R+ Sbjct: 475 SLEGNPKVVFLIDSFKVKIKVRQ 497
>CP17A_MACFA (Q2XVA1) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 508 Score = 35.4 bits (80), Expect = 0.035 Identities = 23/83 (27%), Positives = 37/83 (44%), Gaps = 2/83 (2%) Frame = -3 Query: 355 DRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELV--SPFP 182 +RF ++ + SY+ FG G C+GE A ++ I LL+ F+ E+ P Sbjct: 415 ERFLNPAGTQLISPSLSYLPFGAGPRSCIGEILARQELFLIMAWLLQRFDLEVPDDGQLP 474 Query: 181 ENDWNAMVVGIKGEVMVNYKRRK 113 + N VV + V K R+ Sbjct: 475 SLEGNPKVVFLIDSFKVKIKVRQ 497
>CP3AR_ONCMY (O42563) Cytochrome P450 3A27 (EC 1.14.14.1) (CYPIIIA27)| Length = 518 Score = 35.4 bits (80), Expect = 0.035 Identities = 16/53 (30%), Positives = 29/53 (54%) Frame = -3 Query: 355 DRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFEL 197 +RF+ +E + ++Y+ FG G C+G FA + IK +L++F F + Sbjct: 422 ERFS--KENKESIDPYTYMPFGAGPRNCIGMRFALIMIKLAMVEILQSFTFSV 472
>CP17A_MESAU (P70687) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 511 Score = 35.4 bits (80), Expect = 0.035 Identities = 15/53 (28%), Positives = 26/53 (49%) Frame = -3 Query: 355 DRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFEL 197 +RF + + SY+ FG G C+GE A ++ HLL+ F+ ++ Sbjct: 415 ERFLDPTGSHLITPSLSYLPFGAGARSCIGEVLARQELFLFMAHLLQRFDLDV 467
>CP6A8_DROME (Q27593) Cytochrome P450 6a8 (EC 1.14.-.-) (CYPVIA8)| Length = 506 Score = 35.0 bits (79), Expect = 0.045 Identities = 20/66 (30%), Positives = 32/66 (48%), Gaps = 3/66 (4%) Frame = -3 Query: 334 EEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVSPFPE---NDWNA 164 EE + +++ FG G C+G F +Q + L+RNF+F S P D + Sbjct: 431 EESAGRPSVAWLPFGDGPRNCIGLRFGQMQARIGLALLIRNFKFSTCSKTPNPLVYDPKS 490 Query: 163 MVVGIK 146 V+G+K Sbjct: 491 FVLGVK 496
>CP2F2_MOUSE (P33267) Cytochrome P450 2F2 (EC 1.14.14.-) (CYPIIF2) (Naphthalene| dehydrogenase) (Naphthalene hydroxylase) (P450-NAH-2) Length = 491 Score = 35.0 bits (79), Expect = 0.045 Identities = 16/41 (39%), Positives = 26/41 (63%), Gaps = 1/41 (2%) Frame = -3 Query: 307 SYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFE-LVSP 188 +++ F GR CLGEP A +++ +T +L+NF + LV P Sbjct: 425 AFMPFSAGRRLCLGEPLARMELFIYFTSILQNFTLQPLVDP 465
>CPXF_STRGO (P18327) Cytochrome P450-SU2 (EC 1.14.-.-) (P450-CVB1) (CYP105B1)| Length = 402 Score = 35.0 bits (79), Expect = 0.045 Identities = 21/58 (36%), Positives = 31/58 (53%), Gaps = 1/58 (1%) Frame = -3 Query: 349 FAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIK-AIWTHLLRNFEFELVSPFPE 179 F G + D A +++FG G H CLG+P A ++++ AI T L R + L P E Sbjct: 326 FPGGDDLDVARDARRHVAFGFGVHQCLGQPLARVELQIAIETLLRRLPDLRLAVPHEE 383
>CP2DF_CANFA (Q29473) Cytochrome P450 2D15 (EC 1.14.14.1) (CYPIID15) (P450 DUT2)| Length = 499 Score = 35.0 bits (79), Expect = 0.045 Identities = 15/42 (35%), Positives = 25/42 (59%) Frame = -3 Query: 307 SYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVSPFP 182 +++ F GR CLGEP A +++ +T LL+ F F + + P Sbjct: 434 AFMPFSAGRRVCLGEPLARMELFLFFTCLLQRFSFSVPAGQP 475
>C12B1_DROAC (O44220) Cytochrome P450 12b1, mitochondrial precursor (EC| 1.14.-.-) (CYPXIIB1) Length = 532 Score = 35.0 bits (79), Expect = 0.045 Identities = 14/43 (32%), Positives = 26/43 (60%) Frame = -3 Query: 310 FSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVSPFP 182 F Y++FG G C+G+ A L+++ + T LLR ++ ++ P Sbjct: 468 FVYLAFGFGPRTCIGKRIAELEMETLLTRLLRRYQVSWLAEMP 510
>CP3AC_CANFA (P24463) Cytochrome P450 3A12 (EC 1.14.14.1) (CYPIIIA12)| (P450-PBD-1) Length = 503 Score = 34.7 bits (78), Expect = 0.059 Identities = 16/52 (30%), Positives = 28/52 (53%) Frame = -3 Query: 355 DRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFE 200 +RF+ R+ ++Y+ FG G C+G FA + +K +L+NF F+ Sbjct: 417 ERFS--RKNKDSINPYTYLPFGTGPRNCIGMRFAIMNMKLALVRVLQNFSFK 466
>CP3A9_RAT (P51538) Cytochrome P450 3A9 (EC 1.14.14.1) (CYPIIIA9) (P450-OLF3)| (Olfactive) (3AH15) Length = 503 Score = 34.7 bits (78), Expect = 0.059 Identities = 15/52 (28%), Positives = 28/52 (53%) Frame = -3 Query: 355 DRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFE 200 +RF+ +++ + Y+ FG G C+G FA + +K +L+NF F+ Sbjct: 417 ERFSKKNQDN--INPYMYLPFGNGPRNCIGMRFALMNMKVALFRVLQNFSFQ 466
>CP134_DROME (Q9VG40) Probable cytochrome P450 313a4 (EC 1.14.-.-)| (CYPCCCXIIIA4) Length = 478 Score = 34.7 bits (78), Expect = 0.059 Identities = 19/57 (33%), Positives = 27/57 (47%) Frame = -3 Query: 355 DRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVSPF 185 D F +DK ++YI F G C+G +A + K LLRN+ F+ PF Sbjct: 399 DHFLPHNIQDK--HPYAYIPFTKGIRNCIGWRYALISAKVTLAKLLRNYRFKTSFPF 453
>CP2D9_MOUSE (P11714) Cytochrome P450 2D9 (EC 1.14.14.1) (CYPIID9)| (P450-16-alpha) (CA) (Testosterone 16-alpha hydroxylase) Length = 504 Score = 34.7 bits (78), Expect = 0.059 Identities = 18/53 (33%), Positives = 29/53 (54%) Frame = -3 Query: 307 SYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVSPFPENDWNAMVVGI 149 +++ F GR CLGE A +++ +T LL+ F F + P+ N+ V GI Sbjct: 435 AFMPFSAGRRSCLGEALARMELFLFFTCLLQRFSFSVPDGQPQPS-NSGVYGI 486
>CP3AT_PIG (P79401) Cytochrome P450 3A29 (EC 1.14.14.1) (CYPIIIA29)| Length = 503 Score = 34.3 bits (77), Expect = 0.077 Identities = 13/37 (35%), Positives = 22/37 (59%) Frame = -3 Query: 310 FSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFE 200 ++Y+ FG G C+G FA + +K +L+NF F+ Sbjct: 430 YTYLPFGTGPRNCIGMRFALMNMKLALVRVLQNFSFK 466
>CP132_MYCTU (P77900) Putative cytochrome P450 132 (EC 1.14.-.-)| Length = 461 Score = 34.3 bits (77), Expect = 0.077 Identities = 13/37 (35%), Positives = 25/37 (67%) Frame = -3 Query: 307 SYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFEL 197 +Y+ FGGGR C+G+ FA +++ + + ++F F+L Sbjct: 398 AYLPFGGGRRICIGQSFALMEMVLMAAIMSQHFTFDL 434
>CP132_MYCBO (P59954) Putative cytochrome P450 132 (EC 1.14.-.-)| Length = 461 Score = 34.3 bits (77), Expect = 0.077 Identities = 13/37 (35%), Positives = 25/37 (67%) Frame = -3 Query: 307 SYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFEL 197 +Y+ FGGGR C+G+ FA +++ + + ++F F+L Sbjct: 398 AYLPFGGGRRICIGQSFALMEMVLMAAIMSQHFTFDL 434
>C135B_MYCTU (P63715) Putative cytochrome P450 135B1 (EC 1.14.-.-)| Length = 472 Score = 34.3 bits (77), Expect = 0.077 Identities = 15/50 (30%), Positives = 25/50 (50%) Frame = -3 Query: 355 DRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFE 206 +RF R +++ FGGG CLG FA ++++ + +LR E Sbjct: 361 ERFDPDRMVGATLSPTTWLPFGGGNRRCLGATFAMVEMRVVLREILRRVE 410
>C135B_MYCBO (P63716) Putative cytochrome P450 135B1 (EC 1.14.-.-)| Length = 472 Score = 34.3 bits (77), Expect = 0.077 Identities = 15/50 (30%), Positives = 25/50 (50%) Frame = -3 Query: 355 DRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFE 206 +RF R +++ FGGG CLG FA ++++ + +LR E Sbjct: 361 ERFDPDRMVGATLSPTTWLPFGGGNRRCLGATFAMVEMRVVLREILRRVE 410
>CP341_MOUSE (Q9JMA7) Cytochrome P450 3A41 (EC 1.14.14.1)| Length = 504 Score = 34.3 bits (77), Expect = 0.077 Identities = 13/37 (35%), Positives = 23/37 (62%) Frame = -3 Query: 310 FSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFE 200 + Y+ FG G C+G FA++ +K T +++NF F+ Sbjct: 431 YLYMPFGIGPRNCIGMRFAFMTMKLALTKVMQNFSFQ 467
>C97B3_ARATH (O23365) Cytochrome P450 97B3 (EC 1.14.-.-)| Length = 580 Score = 34.3 bits (77), Expect = 0.077 Identities = 13/44 (29%), Positives = 25/44 (56%) Frame = -3 Query: 328 DKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFEL 197 +++ F+++ FGGG C+G+ FA ++ L + F+ EL Sbjct: 507 NEIIADFAFLPFGGGPRKCIGDQFALMESTVALAMLFQKFDVEL 550
>C86A2_ARATH (O23066) Cytochrome P450 86A2 (EC 1.14.-.-)| Length = 553 Score = 34.3 bits (77), Expect = 0.077 Identities = 18/69 (26%), Positives = 33/69 (47%) Frame = -3 Query: 310 FSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVSPFPENDWNAMVVGIKGEVMV 131 + +++F G CLG+ AYLQ+K I +L + ++ + +K ++V Sbjct: 447 YRFVAFNAGPRICLGKDLAYLQMKTIAAAVLLRHRLTVAPGHKVEQKMSLTLFMKNGLLV 506 Query: 130 NYKRRKLVV 104 N +R L V Sbjct: 507 NVHKRDLEV 515
>C505_FUSOX (Q9Y8G7) Bifunctional P-450:NADPH-P450 reductase (Fatty acid| omega-hydroxylase) (P450foxy) [Includes: Cytochrome P450 505 (EC 1.14.14.1); NADPH--cytochrome P450 reductase (EC 1.6.2.4)] Length = 1066 Score = 34.3 bits (77), Expect = 0.077 Identities = 13/36 (36%), Positives = 19/36 (52%) Frame = -3 Query: 295 FGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVSP 188 FG G+ C+G PFA+ + L +NF F + P Sbjct: 400 FGNGKRACIGRPFAWQESLLAMVVLFQNFNFTMTDP 435
>CP3AJ_CAPAE (P79152) Cytochrome P450 3A19 (EC 1.14.14.1) (CYPIIIA19) (Fragment)| Length = 218 Score = 33.9 bits (76), Expect = 0.10 Identities = 14/36 (38%), Positives = 20/36 (55%) Frame = -3 Query: 310 FSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEF 203 + Y+ FG G C+G FA + IK +L+NF F Sbjct: 141 YVYLPFGTGPRNCVGMRFALMNIKLALVRILQNFSF 176
>C6A19_DROME (P82711) Probable cytochrome P450 6a19 (EC 1.14.-.-) (CYPVIA19)| Length = 503 Score = 33.9 bits (76), Expect = 0.10 Identities = 21/72 (29%), Positives = 37/72 (51%), Gaps = 3/72 (4%) Frame = -3 Query: 334 EEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFEL--VSPFP-ENDWNA 164 E+ K +++ FG G C+G F +Q+ L+ NF FEL +P P + N Sbjct: 425 EQVKKRPTCAFLPFGAGPRNCIGLRFGRMQVIIGLALLIHNFRFELHPKTPVPMKYTINN 484 Query: 163 MVVGIKGEVMVN 128 +++G +G + +N Sbjct: 485 LLLGSEGGIHLN 496
>C5B3_AMYOR (Q8RN04) Cytochrome P450 165B3 (EC 1.14.-.-) (Vancomycin| biosynthesis protein oxyB) Length = 398 Score = 33.9 bits (76), Expect = 0.10 Identities = 13/32 (40%), Positives = 21/32 (65%) Frame = -3 Query: 304 YISFGGGRHGCLGEPFAYLQIKAIWTHLLRNF 209 +++FG G H CLG A L+++ ++T L R F Sbjct: 337 HVAFGHGVHHCLGAALARLELRTVFTELWRRF 368
>CP4V2_PONPY (Q5RCN6) Cytochrome P450 4V2 (EC 1.14.-.-)| Length = 525 Score = 33.9 bits (76), Expect = 0.10 Identities = 13/37 (35%), Positives = 23/37 (62%) Frame = -3 Query: 310 FSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFE 200 ++Y+ F G C+G+ FA ++ K I + +LR+F E Sbjct: 455 YAYVPFSAGPRNCIGQKFAVMEEKTILSCILRHFWIE 491
>CP4V2_HUMAN (Q6ZWL3) Cytochrome P450 4V2 (EC 1.14.-.-)| Length = 525 Score = 33.9 bits (76), Expect = 0.10 Identities = 13/37 (35%), Positives = 23/37 (62%) Frame = -3 Query: 310 FSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFE 200 ++Y+ F G C+G+ FA ++ K I + +LR+F E Sbjct: 455 YAYVPFSAGPRNCIGQKFAVMEEKTILSCILRHFWIE 491
>CP39A_HUMAN (Q9NYL5) Cytochrome P450 39A1 (EC 1.14.13.99)| (24-hydroxycholesterol 7-alpha-hydroxylase) (Oxysterol 7-alpha-hydroxylase) (hCYP39A1) Length = 469 Score = 33.9 bits (76), Expect = 0.10 Identities = 17/66 (25%), Positives = 36/66 (54%), Gaps = 3/66 (4%) Frame = -3 Query: 304 YISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVSPFPENDWNAMVVGI---KGEVM 134 +++FG G+ C FA L+++ +L ++ L+ P P+ + +VG+ +G+ Sbjct: 404 FMAFGSGKFQCPARWFALLEVQMCIILILYKYDCSLLDPLPKQSY-LHLVGVPQPEGQCR 462 Query: 133 VNYKRR 116 + YK+R Sbjct: 463 IEYKQR 468
>CP392_DROME (P82713) Probable cytochrome P450 309a2 (EC 1.14.-.-) (CYPCCCIXA2)| Length = 538 Score = 33.9 bits (76), Expect = 0.10 Identities = 20/64 (31%), Positives = 33/64 (51%), Gaps = 2/64 (3%) Frame = -3 Query: 304 YISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVSP--FPENDWNAMVVGIKGEVMV 131 ++ F G C+G P A L +K+ H+L NF+ P+ D VV ++G+V + Sbjct: 473 FLPFSDGPRICMGVPLAMLTLKSALVHILSNFQVVRGRDRLIPKGDSGFGVV-LQGDVNL 531 Query: 130 NYKR 119 Y+R Sbjct: 532 EYRR 535
>C4AA1_DROME (Q9V7G5) Probable cytochrome P450 4aa1 (EC 1.14.-.-) (CYPIVAA1)| Length = 514 Score = 33.9 bits (76), Expect = 0.10 Identities = 15/50 (30%), Positives = 30/50 (60%) Frame = -3 Query: 355 DRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFE 206 +RF+ E++ ++++ F G C+G FA ++IK I + LLR+++ Sbjct: 429 ERFSPENSENR--HPYAFLPFSAGPRYCIGNRFAIMEIKTIVSRLLRSYQ 476
>CP3AF_CAVPO (Q64406) Cytochrome P450 3A15 (EC 1.14.14.1) (CYPIIIA15)| Length = 503 Score = 33.5 bits (75), Expect = 0.13 Identities = 16/51 (31%), Positives = 26/51 (50%) Frame = -3 Query: 355 DRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEF 203 +RF+ +E+ + Y+ FG G C+G A + +K LL+NF F Sbjct: 417 ERFSKKNKEN--IDPYIYMPFGNGPRNCIGRRMALMNLKLALIRLLQNFSF 465
>CP343_HUMAN (Q9HB55) Cytochrome P450 3A43 (EC 1.14.14.1)| Length = 503 Score = 33.5 bits (75), Expect = 0.13 Identities = 15/37 (40%), Positives = 19/37 (51%) Frame = -3 Query: 310 FSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFE 200 + YI FG G C+G FA IK L+NF F+ Sbjct: 430 YRYIPFGAGPRNCIGMRFALTNIKLAVIRALQNFSFK 466
>CP11B_RANCA (Q92104) Cytochrome P450 11B, mitochondrial precursor (EC| 1.14.15.4) (CYPXIB) (P450C11) (Steroid 11-beta-hydroxylase) (P-450(11 beta,aldo)) Length = 517 Score = 33.5 bits (75), Expect = 0.13 Identities = 14/40 (35%), Positives = 22/40 (55%) Frame = -3 Query: 310 FSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVS 191 F ++FG G C+G A +I H+L+NF+ + VS Sbjct: 453 FKALAFGFGSRQCIGRRIAETEITLFLMHMLKNFQIDTVS 492
>C6A14_DROME (Q9V4U7) Probable cytochrome P450 6a14 (EC 1.14.-.-) (CYPVIA14)| Length = 509 Score = 33.5 bits (75), Expect = 0.13 Identities = 17/46 (36%), Positives = 23/46 (50%) Frame = -3 Query: 334 EEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFEL 197 EE K +Y+ FG G C+G F +Q K LLR F+F + Sbjct: 434 EEVKNRHPMAYLPFGDGPRNCIGLRFGKIQAKIGLVSLLRRFKFSV 479
>CP3AG_MOUSE (Q64481) Cytochrome P450 3A16 (EC 1.14.14.1) (CYPIIIA16)| Length = 504 Score = 33.5 bits (75), Expect = 0.13 Identities = 13/37 (35%), Positives = 21/37 (56%) Frame = -3 Query: 310 FSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFE 200 + Y+ FG G C+G FA + +K +L+NF F+ Sbjct: 431 YVYLPFGNGPRNCIGMRFALMNMKLALIKVLQNFSFQ 467
>CP2K3_ONCMY (O93299) Cytochrome P450 2K3 (EC 1.14.14.1) (CYPIIK3) (P450 LMC2)| Length = 491 Score = 33.5 bits (75), Expect = 0.13 Identities = 15/45 (33%), Positives = 26/45 (57%) Frame = -3 Query: 307 SYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVSPFPEND 173 ++++F GR CLGE A +++ +T LL++F F E+D Sbjct: 423 AFMAFSAGRRVCLGEGLARMELFLFFTSLLQHFRFSPPPGVTEDD 467
>CP17A_PANTR (Q8HYN1) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 508 Score = 33.5 bits (75), Expect = 0.13 Identities = 16/53 (30%), Positives = 27/53 (50%) Frame = -3 Query: 355 DRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFEL 197 +RF ++ + SY+ FG G C+GE A ++ I LL+ F+ E+ Sbjct: 415 ERFLNPAGTQLISPSVSYLPFGAGPRSCIGEILARQELFLIMAWLLQRFDLEV 467
>CP17A_HUMAN (P05093) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-monooxygenase) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 508 Score = 33.5 bits (75), Expect = 0.13 Identities = 16/53 (30%), Positives = 27/53 (50%) Frame = -3 Query: 355 DRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFEL 197 +RF ++ + SY+ FG G C+GE A ++ I LL+ F+ E+ Sbjct: 415 ERFLNPAGTQLISPSVSYLPFGAGPRSCIGEILARQELFLIMAWLLQRFDLEV 467
>CP17A_CAVPO (Q64410) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 508 Score = 33.5 bits (75), Expect = 0.13 Identities = 17/53 (32%), Positives = 26/53 (49%) Frame = -3 Query: 355 DRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFEL 197 +RF + + SY+ FG G C+GE A +I I LL+ F+ E+ Sbjct: 415 ERFLDPTGSQIIVPSSSYLPFGAGPRSCVGEALARQEIFLITAWLLQKFDLEV 467
>CP11A_MOUSE (Q9QZ82) Cytochrome P450 11A1, mitochondrial precursor (EC| 1.14.15.6) (CYPXIA1) (P450(scc)) (Cholesterol side-chain cleavage enzyme) (Cholesterol desmolase) Length = 526 Score = 33.5 bits (75), Expect = 0.13 Identities = 15/38 (39%), Positives = 21/38 (55%) Frame = -3 Query: 310 FSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFEL 197 F Y+ FG G CLG A L++ + +LL NF E+ Sbjct: 446 FRYLGFGWGVRQCLGRRIAELEMTILLINLLENFRIEV 483
>C71A2_SOLME (P37118) Cytochrome P450 71A2 (EC 1.14.-.-) (CYPLXXIA2) (P-450EG4)| Length = 505 Score = 33.5 bits (75), Expect = 0.13 Identities = 15/38 (39%), Positives = 19/38 (50%) Frame = -3 Query: 310 FSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFEL 197 F + FG GR GC G FA I+ L+ F+F L Sbjct: 436 FKLLPFGAGRRGCPGSSFAIAVIELALARLVHKFDFAL 473
>CP4FC_HUMAN (Q9HCS2) Cytochrome P450 4F12 (EC 1.14.14.1) (CYPIVF12)| Length = 524 Score = 33.5 bits (75), Expect = 0.13 Identities = 15/51 (29%), Positives = 24/51 (47%) Frame = -3 Query: 355 DRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEF 203 D F E K ++I F G C+G+ FA ++K + +L +F F Sbjct: 441 DPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRF 491
>YJIB_BACSU (O34374) Putative cytochrome P450 yjiB (EC 1.14.-.-)| Length = 396 Score = 33.5 bits (75), Expect = 0.13 Identities = 21/54 (38%), Positives = 29/54 (53%), Gaps = 1/54 (1%) Frame = -3 Query: 304 YISFGGGRHGCLGEPFAYLQIKAIWTHLLRNF-EFELVSPFPENDWNAMVVGIK 146 +I+FG G H CLG P A L+ T L+ F E VS P N+++ G+K Sbjct: 339 HIAFGHGIHFCLGAPLARLEANIALTSLISAFPHMECVSITPIE--NSVIYGLK 390
>CP317_DROME (Q9V776) Probable cytochrome P450 317a1 (EC 1.14.-.-)| (CYPCCCXVIIA1) Length = 518 Score = 33.5 bits (75), Expect = 0.13 Identities = 18/53 (33%), Positives = 28/53 (52%) Frame = -3 Query: 355 DRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFEL 197 DR++ R+ + G ++ FG G C+G FA LQ++ LL +EF L Sbjct: 436 DRWSGPRDSLQEQG--TWFGFGVGARSCIGIQFAQLQLRLALALLLSEYEFSL 486
>C13A7_CAEEL (Q27519) Putative cytochrome P450 CYP13A7 (EC 1.14.-.-)| Length = 518 Score = 33.5 bits (75), Expect = 0.13 Identities = 13/35 (37%), Positives = 23/35 (65%) Frame = -3 Query: 304 YISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFE 200 Y+ FG G C+G A +++K + T++L+N+ FE Sbjct: 454 YLPFGMGPRICIGMRLAMMEMKMLLTNILKNYTFE 488
>CPXM_BACME (Q06069) Cytochrome P450(MEG) (EC 1.14.99.-) (Steroid| 15-beta-hydroxylase) (Steroid 15-beta-monooxygenase) Length = 410 Score = 33.5 bits (75), Expect = 0.13 Identities = 14/33 (42%), Positives = 20/33 (60%) Frame = -3 Query: 304 YISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFE 206 +++FG G H CLG P A L+ K T L+ F+ Sbjct: 345 HLTFGNGPHFCLGAPLARLEAKIALTAFLKKFK 377
>CP52M_DEBHA (Q9Y758) Cytochrome P450 52A13 (EC 1.14.14.-) (Alkane hydroxylase| 2) (Alkane-inducible p450alk 2) (DH-ALK2) Length = 519 Score = 33.1 bits (74), Expect = 0.17 Identities = 17/50 (34%), Positives = 25/50 (50%) Frame = -3 Query: 355 DRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFE 206 D F R + ++Y+ F GG CLG+ FA + I T LL+ F+ Sbjct: 439 DEFKPERWAESRKLGWAYVPFNGGPRICLGQQFALTEASYIVTRLLQMFD 488
>PTGIS_RAT (Q62969) Prostacyclin synthase (EC 5.3.99.4) (Prostaglandin I2| synthase) Length = 501 Score = 33.1 bits (74), Expect = 0.17 Identities = 22/66 (33%), Positives = 34/66 (51%), Gaps = 6/66 (9%) Frame = -3 Query: 295 FGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVS---PFPENDWNAMVVGI---KGEVM 134 +G G + CLG+ +A IK LL +F+ ELVS PE D + G+ + +V Sbjct: 435 WGAGHNQCLGKSYAINSIKQFVVLLLTHFDLELVSEDTEVPEFDLSRYGFGLMQPEEDVP 494 Query: 133 VNYKRR 116 + Y+ R Sbjct: 495 IRYRTR 500
>CP17A_SHEEP (Q29497) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 509 Score = 33.1 bits (74), Expect = 0.17 Identities = 15/53 (28%), Positives = 26/53 (49%) Frame = -3 Query: 355 DRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFEL 197 +RF ++ + SY+ FG G C+GE A ++ + LL+ F E+ Sbjct: 415 ERFLDPTGTQLISPSLSYLPFGAGPRSCVGEMLARQELFLFMSRLLQRFNLEI 467
>CP17A_PIG (P19100) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 509 Score = 33.1 bits (74), Expect = 0.17 Identities = 16/53 (30%), Positives = 26/53 (49%) Frame = -3 Query: 355 DRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFEL 197 +RF ++ + SY+ FG G C+GE A ++ LL+ F+ EL Sbjct: 415 ERFLDPTGTQLISPSLSYLPFGAGPRSCVGEMLARQELFLFTAGLLQRFDLEL 467
>CP17A_CAPHI (Q9N0U7) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 509 Score = 33.1 bits (74), Expect = 0.17 Identities = 15/53 (28%), Positives = 26/53 (49%) Frame = -3 Query: 355 DRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFEL 197 +RF ++ + SY+ FG G C+GE A ++ + LL+ F E+ Sbjct: 415 ERFLDPTGTQLISPSLSYLPFGAGPRSCVGEMLARQELFLFMSRLLQRFNLEI 467
>CP17A_BOVIN (P05185) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 509 Score = 33.1 bits (74), Expect = 0.17 Identities = 15/53 (28%), Positives = 26/53 (49%) Frame = -3 Query: 355 DRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFEL 197 +RF ++ + SY+ FG G C+GE A ++ + LL+ F E+ Sbjct: 415 ERFLDPTGTQLISPSLSYLPFGAGPRSCVGEMLARQELFLFMSRLLQRFNLEI 467
>CP17A_BISBI (Q9GMC7) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 509 Score = 33.1 bits (74), Expect = 0.17 Identities = 15/53 (28%), Positives = 26/53 (49%) Frame = -3 Query: 355 DRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFEL 197 +RF ++ + SY+ FG G C+GE A ++ + LL+ F E+ Sbjct: 415 ERFLDPTGTQLISPSLSYLPFGAGPRSCVGEMLARQELFLFMSRLLQRFNLEI 467
>PID9_FUSSO (Q12645) Pisatin demethylase (EC 1.14.-.-) (Cytochrome P450 57A1)| Length = 515 Score = 33.1 bits (74), Expect = 0.17 Identities = 14/53 (26%), Positives = 28/53 (52%) Frame = -3 Query: 355 DRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFEL 197 +R+ E + G+F+ FG G C+G+ + L++ ++RNF+ E+ Sbjct: 429 ERWLEANENINIGGSFA---FGAGSRSCIGKNISILEMSKAIPQIVRNFDIEI 478
>CP2K4_ONCMY (O93297) Cytochrome P450 2K4 (EC 1.14.14.1) (CYPIIK4)| Length = 504 Score = 33.1 bits (74), Expect = 0.17 Identities = 15/45 (33%), Positives = 25/45 (55%) Frame = -3 Query: 307 SYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVSPFPEND 173 ++++F GR CLGE A +++ +T LL+ F F E+D Sbjct: 436 AFMAFSAGRRVCLGEGLARMELFLFFTSLLQRFRFSPPPGVTEDD 480
>CP2K1_ONCMY (Q92090) Cytochrome P450 2K1 (EC 1.14.14.1) (CYPIIK1) (P450 LMC2)| Length = 504 Score = 33.1 bits (74), Expect = 0.17 Identities = 15/45 (33%), Positives = 25/45 (55%) Frame = -3 Query: 307 SYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVSPFPEND 173 ++++F GR CLGE A +++ +T LL+ F F E+D Sbjct: 436 AFMAFSAGRRVCLGEGLARMELFLFFTSLLQRFRFSPPPGVTEDD 480
>CP2F2_RAT (O35293) Cytochrome P450 2F2 (EC 1.14.14.-) (CYPIIF2) (Naphthalene| dehydrogenase) (Naphthalene hydroxylase) (P450-NAH-2) Length = 491 Score = 33.1 bits (74), Expect = 0.17 Identities = 16/41 (39%), Positives = 24/41 (58%), Gaps = 1/41 (2%) Frame = -3 Query: 307 SYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFE-LVSP 188 +++ F GR CLGEP A +++ T +L+NF LV P Sbjct: 425 AFMPFSAGRRLCLGEPLARMELFIYLTSILQNFTLHPLVEP 465
>CP137_MYCTU (O69653) Putative cytochrome P450 137 (EC 1.14.-.-)| Length = 476 Score = 33.1 bits (74), Expect = 0.17 Identities = 16/44 (36%), Positives = 24/44 (54%) Frame = -3 Query: 310 FSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVSPFPE 179 ++++ FGGG CLG F+ ++ + LLR EF V PE Sbjct: 410 YAWVPFGGGVKRCLGANFSMRELITVLHVLLREGEFTAVDDEPE 453
>CP11A_PIG (P10612) Cytochrome P450 11A1, mitochondrial precursor (EC| 1.14.15.6) (CYPXIA1) (P450(scc)) (Cholesterol side-chain cleavage enzyme) (Cholesterol desmolase) Length = 520 Score = 33.1 bits (74), Expect = 0.17 Identities = 17/48 (35%), Positives = 25/48 (52%) Frame = -3 Query: 340 GREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFEL 197 G+E D + F + FG G C+G A L++ H+L NF+ EL Sbjct: 441 GKERDLIH--FRNLGFGWGVRQCVGRRIAELEMTLFLIHILENFKVEL 486
>C11B1_MESAU (P97720) Cytochrome P450 11B1, mitochondrial precursor (EC| 1.14.15.4) (CYPXIB1) (P450C11) (Steroid 11-beta-hydroxylase) Length = 499 Score = 33.1 bits (74), Expect = 0.17 Identities = 13/39 (33%), Positives = 25/39 (64%) Frame = -3 Query: 316 GAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFE 200 G+F +++FG G CLG+ A +++ + H+L++F E Sbjct: 432 GSFQHLTFGFGVRQCLGKRLAQVEMLLLLHHVLKSFRVE 470
>C11B2_MESAU (Q64658) Cytochrome P450 11B2, mitochondrial precursor (EC| 1.14.15.4) (EC 1.14.15.5) (C450XIB2) (Aldosterone synthase) (P-450Aldo) (ALDOS) (Aldosterone-synthesizing enzyme) (Steroid 18-hydroxylase) (P-450C18) Length = 500 Score = 33.1 bits (74), Expect = 0.17 Identities = 13/39 (33%), Positives = 25/39 (64%) Frame = -3 Query: 316 GAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFE 200 G+F +++FG G CLG+ A +++ + H+L++F E Sbjct: 433 GSFQHLTFGFGVRQCLGKRLAQVEMLLLLHHVLKSFRVE 471
>CP4B1_HUMAN (P13584) Cytochrome P450 4B1 (EC 1.14.14.1) (CYPIVB1) (P450-HP)| Length = 511 Score = 33.1 bits (74), Expect = 0.17 Identities = 13/38 (34%), Positives = 21/38 (55%) Frame = -3 Query: 310 FSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFEL 197 F+++ F G C+G+ FA ++K + L FEF L Sbjct: 441 FAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSL 478
>CP17A_ICTPU (O73853) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 514 Score = 33.1 bits (74), Expect = 0.17 Identities = 19/61 (31%), Positives = 28/61 (45%), Gaps = 2/61 (3%) Frame = -3 Query: 355 DRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELV--SPFP 182 +RF + SY+ FG G CLGE A L++ + +L+ F E+ P P Sbjct: 418 ERFLNEEGNSLCCPSLSYLPFGAGVRVCLGEALAKLELFLFLSWILQRFTLEVPGGQPLP 477 Query: 181 E 179 E Sbjct: 478 E 478
>CPXI_BACME (P14762) Cytochrome P450(BM-1) (EC 1.14.14.-)| Length = 410 Score = 33.1 bits (74), Expect = 0.17 Identities = 16/42 (38%), Positives = 23/42 (54%) Frame = -3 Query: 304 YISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVSPFPE 179 +++FG G H CLG P A L++K I L F + PF + Sbjct: 346 HLTFGNGPHFCLGAPLARLEMKIILEAFLEAFSH--IEPFED 385
>CP3AO_SHEEP (Q29496) Cytochrome P450 3A24 (EC 1.14.14.1) (CYPIIIA24)| Length = 503 Score = 32.7 bits (73), Expect = 0.22 Identities = 13/37 (35%), Positives = 21/37 (56%) Frame = -3 Query: 310 FSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFE 200 + Y+ FG G C+G FA + +K +L+NF F+ Sbjct: 430 YVYLPFGTGPRNCIGMRFAIMNMKLAIVRVLQNFSFK 466
>CP3AH_CAVPO (Q64409) Cytochrome P450 3A17 (EC 1.14.14.1) (CYPIIIA17)| Length = 503 Score = 32.7 bits (73), Expect = 0.22 Identities = 16/51 (31%), Positives = 26/51 (50%) Frame = -3 Query: 355 DRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEF 203 +RF+ +E+ + Y+ FG G C+G A + +K LL+NF F Sbjct: 417 ERFSKKNKEN--IDPYIYMPFGNGPRNCIGMRMALMNLKLALIRLLQNFSF 465
>CP3AE_CAVPO (Q64417) Cytochrome P450 3A14 (EC 1.14.14.1) (CYPIIIA14)| Length = 503 Score = 32.7 bits (73), Expect = 0.22 Identities = 16/51 (31%), Positives = 26/51 (50%) Frame = -3 Query: 355 DRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEF 203 +RF+ +E+ + Y+ FG G C+G A + +K LL+NF F Sbjct: 417 ERFSKKNKEN--IDPYIYMPFGNGPRNCIGMRMALMNLKLALIRLLQNFSF 465
>CP17A_SQUAC (Q92113) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 509 Score = 32.7 bits (73), Expect = 0.22 Identities = 19/66 (28%), Positives = 32/66 (48%), Gaps = 5/66 (7%) Frame = -3 Query: 355 DRFAAGREEDK-----VAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVS 191 D F GR D+ + + SY+ FG G CLGE A +++ + +L+ F ++ Sbjct: 413 DAFDPGRFLDEDGKYVCSSSESYLPFGAGTRVCLGEMLARMELFLFTSWILQRFTVQVPP 472 Query: 190 PFPEND 173 +P D Sbjct: 473 GYPPPD 478
>C71A4_SOLME (P37117) Cytochrome P450 71A4 (EC 1.14.-.-) (CYPLXXIA4) (P-450EG2)| Length = 507 Score = 32.7 bits (73), Expect = 0.22 Identities = 15/38 (39%), Positives = 18/38 (47%) Frame = -3 Query: 310 FSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFEL 197 F + FG GR GC G FA I+ L+ F F L Sbjct: 436 FELLPFGSGRRGCPGSSFAIAVIELALARLVHKFNFAL 473
>CP4B1_RAT (P15129) Cytochrome P450 4B1 (EC 1.14.14.1) (CYPIVB1) (P450-isozyme| 5) (P450 L-2) Length = 510 Score = 32.7 bits (73), Expect = 0.22 Identities = 17/50 (34%), Positives = 25/50 (50%) Frame = -3 Query: 346 AAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFEL 197 AAGR F+++ F G C+G+ FA ++K + L FEF L Sbjct: 434 AAGRHP------FAFMPFSAGPRNCIGQQFAMNEMKVVTALCLLRFEFSL 477
>CP131_DROME (Q9VFJ0) Probable cytochrome P450 313a1 (EC 1.14.-.-)| (CYPCCCXIIIA1) Length = 492 Score = 32.7 bits (73), Expect = 0.22 Identities = 16/50 (32%), Positives = 25/50 (50%) Frame = -3 Query: 355 DRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFE 206 D F A E K ++YI F G+ C+G +A + K +LRN++ Sbjct: 413 DNFLAENMEQK--HPYAYIPFARGKRNCIGSKYAMMSSKFALCRILRNYK 460
>CP6B5_PAPGL (Q95036) Cytochrome P450 6B5 (EC 1.14.14.1) (CYPVIB5) (CYP6B5V1)| (Fragment) Length = 476 Score = 32.7 bits (73), Expect = 0.22 Identities = 15/36 (41%), Positives = 19/36 (52%) Frame = -3 Query: 307 SYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFE 200 +YI FG G+ CLG F Q++ LL F FE Sbjct: 432 AYIPFGAGQRKCLGMRFGQWQVQVCIIKLLSKFRFE 467
>C12B2_DROME (Q9V8M2) Probable cytochrome P450 12b2, mitochondrial precursor (EC| 1.14.-.-) (CYPXIIB2) Length = 561 Score = 32.7 bits (73), Expect = 0.22 Identities = 15/58 (25%), Positives = 31/58 (53%) Frame = -3 Query: 310 FSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVSPFPENDWNAMVVGIKGEV 137 F Y+ FG G C+G+ A L+I+ + LLR+++ + P + +++ G++ Sbjct: 493 FVYLPFGFGPRTCIGKRIAELEIETLLVRLLRSYKVSWLPETPIEYESTIILSPCGDI 550
>CP4P2_DROME (Q9V557) Probable cytochrome P450 4p2 (EC 1.14.-.-) (CYPIVP2)| Length = 520 Score = 32.7 bits (73), Expect = 0.22 Identities = 16/69 (23%), Positives = 35/69 (50%), Gaps = 1/69 (1%) Frame = -3 Query: 310 FSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFE-FELVSPFPENDWNAMVVGIKGEVM 134 ++YI F G+ C+G+ +A ++K + +L++F+ ++ P + + K ++ Sbjct: 452 YAYIPFSAGQRNCIGQKYAMQEMKTLMVVILKHFKILPVIDPKSIVFQVGITLRFKNKIK 511 Query: 133 VNYKRRKLV 107 V RR V Sbjct: 512 VKLVRRNCV 520
>C76A2_SOLME (P37122) Cytochrome P450 76A2 (EC 1.14.-.-) (CYPLXXVIA2) (P-450EG7)| Length = 505 Score = 32.7 bits (73), Expect = 0.22 Identities = 20/54 (37%), Positives = 26/54 (48%), Gaps = 3/54 (5%) Frame = -3 Query: 340 GREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFEL---VSP 188 G + D + I FG GR C+G P + + LLR FE+EL VSP Sbjct: 426 GSKIDVKGQHYGLIPFGAGRRMCVGLPLGHRMMHFALGSLLREFEWELPDGVSP 479
>C72A1_CATRO (Q05047) Cytochrome P450 72A1 (EC 1.3.3.9) (CYPLXXII) (Secologanin| synthase) (SLS) Length = 524 Score = 32.7 bits (73), Expect = 0.22 Identities = 18/63 (28%), Positives = 31/63 (49%) Frame = -3 Query: 307 SYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVSPFPENDWNAMVVGIKGEVMVN 128 +Y+ F G CLG+ FA LQ K +L+ F+F++ + + + V + V Sbjct: 459 TYLPFSWGPRVCLGQNFALLQAKLGLAMILQRFKFDVAPSYVHAPFTILTVQPQFGSHVI 518 Query: 127 YKR 119 YK+ Sbjct: 519 YKK 521
>C71D8_SOYBN (O81974) Cytochrome P450 71D8 (EC 1.14.-.-) (P450 CP7)| Length = 504 Score = 32.7 bits (73), Expect = 0.22 Identities = 22/65 (33%), Positives = 26/65 (40%), Gaps = 4/65 (6%) Frame = -3 Query: 355 DRFAAGREEDKV----AGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVSP 188 DRF R D +F YI FG GR C G F I LL +F +EL + Sbjct: 413 DRFIPERFNDSSIDFKGNSFEYIPFGAGRRMCPGMTFGLASITLPLALLLYHFNWELPNK 472 Query: 187 FPEND 173 D Sbjct: 473 MKPED 477
>C13A5_CAEEL (Q27514) Putative cytochrome P450 CYP13A5 (EC 1.14.-.-)| Length = 520 Score = 32.7 bits (73), Expect = 0.22 Identities = 17/52 (32%), Positives = 28/52 (53%) Frame = -3 Query: 355 DRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFE 200 +R+ +G E G Y+ FG G C+G A ++ K + TH+L+ + FE Sbjct: 439 ERWESGDELFYAKGG--YLPFGMGPRICIGMRLAMMEKKMLLTHILKKYTFE 488
>C71A8_MENPI (Q42716) Cytochrome P450 71A8 (EC 1.14.-.-)| Length = 502 Score = 32.7 bits (73), Expect = 0.22 Identities = 14/38 (36%), Positives = 21/38 (55%) Frame = -3 Query: 310 FSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFEL 197 F I FG GR GC G F ++ +L++ F++EL Sbjct: 435 FELIPFGAGRRGCPGTTFPMATLEFTLANLMQKFDWEL 472
>CP6B4_PAPGL (Q27902) Cytochrome P450 6B4 (EC 1.14.14.1) (CYPVIB4)| (CYP6B4V1/CYP6B4V2) Length = 500 Score = 32.7 bits (73), Expect = 0.22 Identities = 15/36 (41%), Positives = 19/36 (52%) Frame = -3 Query: 307 SYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFE 200 +YI FG G+ CLG F Q++ LL F FE Sbjct: 432 AYIPFGAGQRKCLGMRFGQWQVQVCIIKLLSKFRFE 467
>CP3AD_MOUSE (Q64464) Cytochrome P450 3A13 (EC 1.14.14.1) (CYPIIIA13)| Length = 503 Score = 32.3 bits (72), Expect = 0.29 Identities = 15/49 (30%), Positives = 27/49 (55%) Frame = -3 Query: 355 DRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNF 209 +RF+ + +D + + Y+ FG G C+G FA + +K +L+NF Sbjct: 417 ERFSK-KNQDSI-NPYMYLPFGSGPRNCIGMRFALINMKVALVRVLQNF 463
>CP3A7_HUMAN (P24462) Cytochrome P450 3A7 (EC 1.14.14.1) (CYPIIIA7) (P450-HFLA)| Length = 503 Score = 32.3 bits (72), Expect = 0.29 Identities = 13/37 (35%), Positives = 20/37 (54%) Frame = -3 Query: 310 FSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFE 200 + Y FG G C+G FA + +K +L+NF F+ Sbjct: 430 YIYTPFGSGPRNCIGMRFALVNMKLALVRVLQNFSFK 466
>CP3A3_HUMAN (P05184) Cytochrome P450 3A3 (EC 1.14.14.1) (CYPIIIA3) (HLp)| Length = 503 Score = 32.3 bits (72), Expect = 0.29 Identities = 13/37 (35%), Positives = 20/37 (54%) Frame = -3 Query: 310 FSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFE 200 + Y FG G C+G FA + +K +L+NF F+ Sbjct: 430 YIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFK 466
>CP4G1_DROME (Q9V3S0) Cytochrome P450 4g1 (EC 1.14.-.-) (CYPIVG1)| Length = 556 Score = 32.3 bits (72), Expect = 0.29 Identities = 11/34 (32%), Positives = 22/34 (64%) Frame = -3 Query: 310 FSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNF 209 +S+I F G C+G +A L++K + + ++RN+ Sbjct: 485 YSFIPFSAGPRSCVGRKYAMLKLKVLLSTIVRNY 518
>CP26A_BRARE (P79739) Cytochrome P450 26A1 (EC 1.14.-.-) (Retinoic| acid-metabolizing cytochrome) (P450RAI) (Retinoic acid 4-hydroxylase) Length = 492 Score = 32.3 bits (72), Expect = 0.29 Identities = 17/48 (35%), Positives = 26/48 (54%) Frame = -3 Query: 355 DRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRN 212 +RF + ED F+YI FGGG C+G+ FA + +K L ++ Sbjct: 413 ERFMSKGLED--GSRFNYIPFGGGSRMCVGKEFAKVLLKIFLVELTQH 458
>THAS_RAT (P49430) Thromboxane-A synthase (EC 5.3.99.5) (TXA synthase) (TXS)| Length = 533 Score = 32.3 bits (72), Expect = 0.29 Identities = 14/37 (37%), Positives = 18/37 (48%) Frame = -3 Query: 310 FSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFE 200 F+Y+ FG G CLG L +K +L F FE Sbjct: 467 FTYLPFGAGPRSCLGVRLGLLVVKLTLLQVLHKFRFE 503
>CP11A_RAT (P14137) Cytochrome P450 11A1, mitochondrial precursor (EC| 1.14.15.6) (CYPXIA1) (P450(scc)) (Cholesterol side-chain cleavage enzyme) (Cholesterol desmolase) Length = 526 Score = 32.3 bits (72), Expect = 0.29 Identities = 15/40 (37%), Positives = 21/40 (52%) Frame = -3 Query: 310 FSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVS 191 F Y+ FG G CLG A L++ ++L NF E+ S Sbjct: 447 FRYLGFGWGVRQCLGRRIAELEMTIFLINVLENFRIEVQS 486
>C13A3_CAEEL (Q27517) Putative cytochrome P450 CYP13A3 (EC 1.14.-.-)| Length = 520 Score = 32.3 bits (72), Expect = 0.29 Identities = 16/52 (30%), Positives = 28/52 (53%) Frame = -3 Query: 355 DRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFE 200 +R+ +G E+ GA Y+ FG G C+G AY++ K + +L+ + E Sbjct: 439 ERWESGDEQAVAKGA--YLPFGLGPRICIGMRLAYMEEKMLLAQILKKYSLE 488
>C28A5_DROME (Q9V419) Probable cytochrome P450 28a5 (EC 1.14.-.-) (CYPXXVIIIA5)| Length = 505 Score = 32.3 bits (72), Expect = 0.29 Identities = 17/65 (26%), Positives = 35/65 (53%), Gaps = 3/65 (4%) Frame = -3 Query: 304 YISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVSPF-PENDW--NAMVVGIKGEVM 134 ++ FG G C+G FA +QIKA L+ F ++ +ND+ ++ G++G + Sbjct: 440 FMGFGDGPRVCIGMRFATVQIKAAIVELISKFNVKINDKTRKDNDYEPGQIITGLRGGIW 499 Query: 133 VNYKR 119 ++ ++ Sbjct: 500 LDLEK 504
>PTGIS_BOVIN (Q29626) Prostacyclin synthase (EC 5.3.99.4) (Prostaglandin I2| synthase) Length = 500 Score = 32.3 bits (72), Expect = 0.29 Identities = 21/68 (30%), Positives = 35/68 (51%), Gaps = 6/68 (8%) Frame = -3 Query: 301 ISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVSP---FPENDWNAMVVGI---KGE 140 + +G G + CLG+ +A IK +L F+ EL++P PE D + G+ + + Sbjct: 432 LPWGAGHNQCLGKGYAVNSIKQFVFLVLTQFDLELITPDVDIPEFDLSRYGFGLMQPEHD 491 Query: 139 VMVNYKRR 116 V V Y+ R Sbjct: 492 VPVRYRIR 499
>CP3A4_HUMAN (P08684) Cytochrome P450 3A4 (EC 1.14.13.67) (Quinine| 3-monooxygenase) (CYPIIIA4) (Nifedipine oxidase) (Taurochenodeoxycholate 6-alpha-hydroxylase) (EC 1.14.13.97) (NF-25) (P450-PCN1) Length = 502 Score = 32.3 bits (72), Expect = 0.29 Identities = 13/37 (35%), Positives = 20/37 (54%) Frame = -3 Query: 310 FSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFE 200 + Y FG G C+G FA + +K +L+NF F+ Sbjct: 429 YIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFK 465
>CP2DG_CAVPO (Q64403) Cytochrome P450 2D16 (EC 1.14.14.1) (CYPIID16)| Length = 500 Score = 32.3 bits (72), Expect = 0.29 Identities = 13/37 (35%), Positives = 22/37 (59%) Frame = -3 Query: 307 SYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFEL 197 +++ F G CLGEP A +++ +T LL+ F F + Sbjct: 435 AFMPFSAGPRICLGEPLARMELFLFFTSLLQRFSFSV 471
>C71D7_SOLCH (P93531) Cytochrome P450 71D7 (EC 1.14.-.-)| Length = 500 Score = 32.3 bits (72), Expect = 0.29 Identities = 16/52 (30%), Positives = 24/52 (46%) Frame = -3 Query: 328 DKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVSPFPEND 173 D + F Y+ FGGGR C G F + LL +F+++L + D Sbjct: 423 DFIGNNFEYLPFGGGRRICPGISFGLANVYLPLAQLLYHFDWKLPTGMEPKD 474
>C4G15_DROME (Q9VYY4) Cytochrome P450 4g15 (EC 1.14.-.-) (CYPIVG15)| Length = 574 Score = 32.3 bits (72), Expect = 0.29 Identities = 13/47 (27%), Positives = 28/47 (59%) Frame = -3 Query: 310 FSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVSPFPENDW 170 ++++ F G C+G +A L++K + + +LRN + + S E+D+ Sbjct: 507 YAFVPFSAGPRSCVGRKYAMLKLKILLSTILRN--YRVYSDLTESDF 551
>C340_ORYLA (Q98T91) Cytochrome P450 3A40 (EC 1.14.14.1)| Length = 502 Score = 32.3 bits (72), Expect = 0.29 Identities = 14/53 (26%), Positives = 28/53 (52%) Frame = -3 Query: 355 DRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFEL 197 +RF+ +E ++Y+ FG G C+G FA + +K +L+ ++F + Sbjct: 418 ERFS--KENKDTFDPYTYMPFGAGPRNCIGMRFALVMMKLAVVEILQTYDFSV 468
>CP301_DROME (Q9V6D6) Probable cytochrome P450 301a1, mitochondrial precursor| (EC 1.14.-.-) (CYPCCCIA1) Length = 553 Score = 32.3 bits (72), Expect = 0.29 Identities = 14/37 (37%), Positives = 23/37 (62%) Frame = -3 Query: 310 FSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFE 200 F+ + +G G CLG FA L+++ + LLRN++ E Sbjct: 490 FASLPYGYGARMCLGRRFADLEMQILLAKLLRNYKLE 526
>CP11A_DASAM (Q92045) Cytochrome P450 11A1, mitochondrial precursor (EC| 1.14.15.6) (CYPXIA1) (P450(SCC)) (Cholesterol side-chain cleavage enzyme) (Cholesterol desmolase) (Fragment) Length = 514 Score = 32.3 bits (72), Expect = 0.29 Identities = 13/37 (35%), Positives = 21/37 (56%) Frame = -3 Query: 310 FSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFE 200 F ++ FG G C+G A Q+ + H+L+NF+ E Sbjct: 449 FRHLGFGFGPRQCIGRRIAETQMVLLMIHMLQNFKIE 485
>CP132_DROME (Q9VGB4) Probable cytochrome P450 313a2 (EC 1.14.-.-)| (CYPCCCXIIIA2) Length = 493 Score = 32.3 bits (72), Expect = 0.29 Identities = 15/68 (22%), Positives = 35/68 (51%), Gaps = 1/68 (1%) Frame = -3 Query: 310 FSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVSPFPENDW-NAMVVGIKGEVM 134 +++I F G+ C+G + + K +LRN++ + P+ ++ + MV+ + Sbjct: 426 YAFIPFSKGKRNCIGWRYGLMSSKLALVKILRNYKLKTSFPYENLEFVDHMVIKLAQSPQ 485 Query: 133 VNYKRRKL 110 + ++RR L Sbjct: 486 LAFERRTL 493
>CP17A_MOUSE (P27786) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 507 Score = 32.0 bits (71), Expect = 0.38 Identities = 13/37 (35%), Positives = 21/37 (56%) Frame = -3 Query: 307 SYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFEL 197 SY+ FG G C+GE A ++ LL+ F+F++ Sbjct: 430 SYLPFGAGPRSCIGEALARQELFIFMALLLQRFDFDV 466
>CP3AV_MESAU (O70537) Cytochrome P450 3A31 (EC 1.14.14.1) (CYPIIIA31) (P450| SH3A-1) Length = 501 Score = 32.0 bits (71), Expect = 0.38 Identities = 12/37 (32%), Positives = 21/37 (56%) Frame = -3 Query: 310 FSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFE 200 + ++ FG G C+G FA + +K T +L+NF + Sbjct: 428 YIFLPFGNGPRNCIGMRFALMNMKLALTKVLQNFSLQ 464
>CP3AL_CALJA (O18993) Cytochrome P450 3A21 (EC 1.14.14.1) (CYPIIIA21) (P450| CM3A-10) Length = 503 Score = 32.0 bits (71), Expect = 0.38 Identities = 15/52 (28%), Positives = 27/52 (51%) Frame = -3 Query: 355 DRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFE 200 +RF+ +++ + Y FG G C+G FA + +K +L+NF F+ Sbjct: 417 ERFSKNNKDN--IDPYIYTPFGTGPRNCIGMRFALMNMKLALIRVLQNFSFK 466
>CP3A8_MACFA (P33268) Cytochrome P450 3A8 (EC 1.14.14.1) (CYPIIIA8) (P450-MKNF2)| (P-450-MK2) Length = 503 Score = 32.0 bits (71), Expect = 0.38 Identities = 13/37 (35%), Positives = 20/37 (54%) Frame = -3 Query: 310 FSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFE 200 + Y FG G C+G FA + +K +L+NF F+ Sbjct: 430 YIYTPFGSGPRNCIGMRFALMNMKLAIIRVLQNFSFK 466
>CP21A_CANFA (Q8WNW0) Cytochrome P450 21 (EC 1.14.99.10) (Cytochrome P450 XXI)| (Steroid 21-hydroxylase) (21-OHase) (P450-C21) (P-450c21) Length = 492 Score = 32.0 bits (71), Expect = 0.38 Identities = 14/31 (45%), Positives = 19/31 (61%) Frame = -3 Query: 301 ISFGGGRHGCLGEPFAYLQIKAIWTHLLRNF 209 ++FG G CLGEP A L++ + LLR F Sbjct: 417 LAFGCGARVCLGEPLARLELLVVLAQLLRAF 447
>F3PH_PETHY (Q9SBQ9) Flavonoid 3'-monooxygenase (EC 1.14.13.21) (Flavonoid| 3'-hydroxylase) (Cytochrome P450 75B2) Length = 512 Score = 32.0 bits (71), Expect = 0.38 Identities = 19/58 (32%), Positives = 27/58 (46%), Gaps = 3/58 (5%) Frame = -3 Query: 355 DRFAAGREEDKV---AGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVS 191 +RF G E+ KV F I FG GR C G ++ + L+ F ++LVS Sbjct: 417 ERFLPGGEKPKVDVRGNDFEVIPFGAGRRICAGMNLGIRMVQLMIATLIHAFNWDLVS 474
>C75A1_PETHY (P48418) Flavonoid 3',5'-hydroxylase 1 (EC 1.14.13.88) (F3'5'H)| (Cytochrome P450 75A1) (CYPLXXVA1) Length = 506 Score = 32.0 bits (71), Expect = 0.38 Identities = 18/57 (31%), Positives = 28/57 (49%), Gaps = 2/57 (3%) Frame = -3 Query: 355 DRFAAGREE--DKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVS 191 +RF +GR D F I FG GR C G + ++ I L+ +F+++L S Sbjct: 414 ERFLSGRNSKIDPRGNDFELIPFGAGRRICAGTRMGIVMVEYILGTLVHSFDWKLPS 470
>THAS_MOUSE (P36423) Thromboxane-A synthase (EC 5.3.99.5) (TXA synthase) (TXS)| (TS) Length = 533 Score = 32.0 bits (71), Expect = 0.38 Identities = 14/37 (37%), Positives = 18/37 (48%) Frame = -3 Query: 310 FSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFE 200 F+Y+ FG G CLG L +K +L F FE Sbjct: 467 FTYLPFGAGPRSCLGVRLGLLVVKLTILQVLHKFRFE 503
>T10H_TAXCU (Q9AXM6) Taxane 10-beta-hydroxylase (EC 1.14.13.76)| (5-alpha-taxadienol-10-beta-hydroxylase) (Cytochrome P450 725A1) Length = 497 Score = 32.0 bits (71), Expect = 0.38 Identities = 13/42 (30%), Positives = 23/42 (54%) Frame = -3 Query: 334 EEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNF 209 +E + ++Y+ FGGG C G F+ ++I H ++NF Sbjct: 423 DEGRHVTPYTYVPFGGGLRTCPGWEFSKIEILLFVHHFVKNF 464
>CP21A_HUMAN (P08686) Cytochrome P450 21 (EC 1.14.99.10) (Cytochrome P450 XXI)| (Steroid 21-hydroxylase) (21-OHase) (P450-C21) (P-450c21) (P450-C21B) Length = 494 Score = 32.0 bits (71), Expect = 0.38 Identities = 14/31 (45%), Positives = 20/31 (64%) Frame = -3 Query: 301 ISFGGGRHGCLGEPFAYLQIKAIWTHLLRNF 209 ++FG G CLGEP A L++ + T LL+ F Sbjct: 419 LAFGCGARVCLGEPLARLELFVVLTRLLQAF 449
>CP11A_CAPHI (P79153) Cytochrome P450 11A1, mitochondrial precursor (EC| 1.14.15.6) (CYPXIA1) (P450(scc)) (Cholesterol side-chain cleavage enzyme) (Cholesterol desmolase) Length = 520 Score = 32.0 bits (71), Expect = 0.38 Identities = 15/48 (31%), Positives = 26/48 (54%) Frame = -3 Query: 340 GREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFEL 197 G+++D + F + FG G C+G A L++ H+L NF+ E+ Sbjct: 441 GKDKDLIH--FRNLGFGWGVRQCVGRRIAELEMTLFLIHILENFKIEM 486
>C75A3_PETHY (P48419) Flavonoid 3',5'-hydroxylase 2 (EC 1.14.13.88) (F3'5'H)| (Cytochrome P450 75A3) (CYPLXXVA3) Length = 508 Score = 32.0 bits (71), Expect = 0.38 Identities = 18/57 (31%), Positives = 28/57 (49%), Gaps = 2/57 (3%) Frame = -3 Query: 355 DRFAAGREE--DKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVS 191 +RF +GR D F I FG GR C G + ++ I L+ +F+++L S Sbjct: 414 ERFLSGRNSKIDPRGNDFELIPFGAGRRICAGTRMGIVMVEYILGTLVHSFDWKLPS 470
>CP9H1_DROME (Q9V6H1) Probable cytochrome P450 9h1 (EC 1.14.-.-) (CYPIXH1)| Length = 518 Score = 32.0 bits (71), Expect = 0.38 Identities = 19/51 (37%), Positives = 28/51 (54%), Gaps = 1/51 (1%) Frame = -3 Query: 355 DRFAAGRE-EDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFE 206 +RFA G E +V Y+ FG G C+G A +++K+I LL NF+ Sbjct: 439 ERFADGHALESRV-----YMPFGVGPRNCIGNRMALMELKSIVYQLLLNFK 484
>C12C1_DROME (Q9VVR9) Probable cytochrome P450 12c1, mitochondrial precursor (EC| 1.14.-.-) (CYPXIIC1) Length = 524 Score = 32.0 bits (71), Expect = 0.38 Identities = 15/43 (34%), Positives = 24/43 (55%) Frame = -3 Query: 328 DKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFE 200 +K AF Y+ FG G C+G+ L+++ +L+RNF E Sbjct: 452 NKDLNAFIYLPFGFGPRMCVGKRIVDLEMELTVANLVRNFHIE 494
>CP11A_HORSE (O46515) Cytochrome P450 11A1, mitochondrial precursor (EC| 1.14.15.6) (CYPXIA1) (P450(scc)) (Cholesterol side-chain cleavage enzyme) (Cholesterol desmolase) Length = 520 Score = 31.6 bits (70), Expect = 0.50 Identities = 15/46 (32%), Positives = 23/46 (50%) Frame = -3 Query: 334 EEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFEL 197 +++K F + FG G CLG A L++ H+L NF E+ Sbjct: 441 DKNKDLTHFRNLGFGWGVRQCLGRRIAELEMTLFLIHILENFRVEI 486
>CP11A_BOVIN (P00189) Cytochrome P450 11A1, mitochondrial precursor (EC| 1.14.15.6) (CYPXIA1) (P450(scc)) (Cholesterol side-chain cleavage enzyme) (Cholesterol desmolase) Length = 520 Score = 31.6 bits (70), Expect = 0.50 Identities = 18/55 (32%), Positives = 27/55 (49%), Gaps = 2/55 (3%) Frame = -3 Query: 355 DRFAAGR--EEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFEL 197 D+F R +DK F + FG G C+G A L++ H+L NF+ E+ Sbjct: 432 DKFDPTRWLSKDKDLIHFRNLGFGWGVRQCVGRRIAELEMTLFLIHILENFKVEM 486
>CP52F_CANTR (P30608) Cytochrome P450 52A6 (EC 1.14.14.-) (CYPLIIA6)| (Alkane-inducible P450-ALK3) Length = 524 Score = 31.6 bits (70), Expect = 0.50 Identities = 13/35 (37%), Positives = 21/35 (60%) Frame = -3 Query: 310 FSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFE 206 ++Y+ F GG CLG+ FA + + T L++ FE Sbjct: 460 WAYVPFNGGPRICLGQQFALTEASYVITRLVQMFE 494
>CP3A5_HUMAN (P20815) Cytochrome P450 3A5 (EC 1.14.14.1) (CYPIIIA5) (P450-PCN3)| (HLp2) Length = 502 Score = 31.6 bits (70), Expect = 0.50 Identities = 13/37 (35%), Positives = 20/37 (54%) Frame = -3 Query: 310 FSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFE 200 + Y FG G C+G FA + +K +L+NF F+ Sbjct: 429 YIYTPFGTGPRNCIGMRFALMNMKLALIRVLQNFSFK 465
>CP17A_HORSE (Q95328) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 508 Score = 31.6 bits (70), Expect = 0.50 Identities = 15/53 (28%), Positives = 25/53 (47%) Frame = -3 Query: 355 DRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFEL 197 +RF ++ + SY+ FG G C+GE A ++ LL+ F E+ Sbjct: 415 ERFLDPTGSQLISPSLSYLPFGAGPRSCIGELLARQELFLFTAWLLQRFNLEV 467
>C90B1_ARATH (O64989) Cytochrome P450 90B1 (EC 1.14.-.-) (Steroid| 22-alpha-hydroxylase) (Dwarf4) (Dwarf protein 4) Length = 513 Score = 31.6 bits (70), Expect = 0.50 Identities = 17/46 (36%), Positives = 24/46 (52%), Gaps = 5/46 (10%) Frame = -3 Query: 319 AGAFS-----YISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFEL 197 +G+FS Y+ FGGG C G A L++ HL+ F +EL Sbjct: 442 SGSFSTWGNNYMPFGGGPRLCAGSELAKLEMAVFIHHLVLKFNWEL 487
>C83A1_ARATH (P48421) Cytochrome P450 83A1 (EC 1.14.-.-) (CYPLXXXIII)| Length = 502 Score = 31.6 bits (70), Expect = 0.50 Identities = 22/77 (28%), Positives = 35/77 (45%) Frame = -3 Query: 337 REEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVSPFPENDWNAMV 158 +E D + +I FG GR C G ++ + +LL +F F+L + +D N V Sbjct: 421 KEVDFKGTDYEFIPFGSGRRMCPGMRLGAAMLEVPYANLLLSFNFKLPNGMKPDDINMDV 480 Query: 157 VGIKGEVMVNYKRRKLV 107 + G M + KLV Sbjct: 481 --MTGLAMHKSQHLKLV 495
>T13H_TAXCU (Q8W4T9) Taxane 13-alpha-hydroxylase (EC 1.14.13.77) (Cytochrome| P450 725A2) Length = 485 Score = 31.6 bits (70), Expect = 0.50 Identities = 17/51 (33%), Positives = 25/51 (49%), Gaps = 2/51 (3%) Frame = -3 Query: 355 DRFAAGR--EEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNF 209 D+F R EE K ++Y+ FGGG C G FA ++ H ++ F Sbjct: 402 DQFKPSRFEEEGKHVTPYTYLPFGGGMRVCPGWEFAKMETLLFLHHFVKAF 452
>C6A20_DROME (Q9V773) Probable cytochrome P450 6a20 (EC 1.14.-.-) (CYPVIA20)| Length = 501 Score = 31.2 bits (69), Expect = 0.65 Identities = 16/47 (34%), Positives = 26/47 (55%), Gaps = 2/47 (4%) Frame = -3 Query: 334 EEDKVAG--AFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFE 200 +ED+V A +++ FG G C+G F +Q+ L+ NF+FE Sbjct: 423 DEDQVQQRPACTFLPFGDGPRNCIGLRFGRMQVIVGMALLIHNFKFE 469
>CP52K_CANMA (Q12589) Cytochrome P450 52A11 (EC 1.14.14.-) (CYPLIIA11)| (Alkane-inducible P450-ALK8) Length = 519 Score = 31.2 bits (69), Expect = 0.65 Identities = 13/41 (31%), Positives = 24/41 (58%) Frame = -3 Query: 310 FSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVSP 188 ++++ F GG CLG+ FA + + L+++FE +SP Sbjct: 454 WAFLPFNGGPRICLGQQFALTEASYVLVRLIQSFETLELSP 494
>CP52J_CANMA (Q12588) Cytochrome P450 52A10 (EC 1.14.14.-) (CYPLIIA10)| (Alkane-inducible P450-ALK7) Length = 519 Score = 31.2 bits (69), Expect = 0.65 Identities = 13/41 (31%), Positives = 24/41 (58%) Frame = -3 Query: 310 FSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVSP 188 ++++ F GG CLG+ FA + + L+++FE +SP Sbjct: 454 WAFLPFNGGPRICLGQQFALTEASYVLARLIQSFETLELSP 494
>CP4AA_MOUSE (O88833) Cytochrome P450 4A10 (EC 1.14.15.3) (CYPIVA10) (Lauric| acid omega-hydroxylase) (P450-LA-omega 1) (P452) Length = 509 Score = 31.2 bits (69), Expect = 0.65 Identities = 14/41 (34%), Positives = 21/41 (51%) Frame = -3 Query: 328 DKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFE 206 D + S++ F GG C+G+ FA ++K I L FE Sbjct: 438 DSPRHSHSFLPFSGGARNCIGKQFAMSELKVIVALTLLRFE 478
>CP3AA_MESAU (Q64148) Cytochrome P450 3A10 (EC 1.14.13.94) (CYPIIIA10)| (Lithocholate 6-beta-hydroxylase) (6 beta-hydroxylase) Length = 503 Score = 31.2 bits (69), Expect = 0.65 Identities = 13/37 (35%), Positives = 20/37 (54%) Frame = -3 Query: 310 FSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFE 200 + Y+ FG G C+G FA L +K +L+NF + Sbjct: 430 YVYMPFGNGPRNCIGMRFALLSMKLAVVSVLQNFTLQ 466
>C11B1_PIG (Q29552) Cytochrome P450 11B1, mitochondrial precursor (EC| 1.14.15.4) (CYPXIB1) (P450C11) (Steroid 11-beta-hydroxylase) Length = 503 Score = 31.2 bits (69), Expect = 0.65 Identities = 13/37 (35%), Positives = 22/37 (59%) Frame = -3 Query: 310 FSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFE 200 F +++FG G CLG A +++ + H+L+NF E Sbjct: 438 FPHLAFGFGMRQCLGRRLAQVEMLLLLHHVLKNFLVE 474
>CP2AC_MOUSE (P56593) Cytochrome P450 2A12 (EC 1.14.14.1) (CYPIIA12) (Steroid| hormones 7-alpha-hydroxylase) (Testosterone 7-alpha-hydroxylase) Length = 492 Score = 31.2 bits (69), Expect = 0.65 Identities = 11/36 (30%), Positives = 24/36 (66%) Frame = -3 Query: 307 SYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFE 200 +++ F G+ CLG+ A +++ ++T +L+NF F+ Sbjct: 426 AFLPFSTGKRFCLGDSLAKMELFFLFTTILQNFRFK 461
>STCF_EMENI (Q12609) Probable sterigmatocystin biosynthesis P450 monooxygenase| STCF (EC 1.14.-.-) (Cytochrome P450 60A2) Length = 506 Score = 31.2 bits (69), Expect = 0.65 Identities = 17/46 (36%), Positives = 24/46 (52%), Gaps = 1/46 (2%) Frame = -3 Query: 295 FGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVSPFPEN-DWNAM 161 F G C+G A +++ I HLL +F+ EL EN DW A+ Sbjct: 417 FSIGPRNCIGRQLALAEMRLILVHLLWHFDIELDRRRMENMDWMAV 462
>CP4B1_RABIT (P15128) Cytochrome P450 4B1 (EC 1.14.14.1) (CYPIVB1) (P450-isozyme| 5) Length = 506 Score = 31.2 bits (69), Expect = 0.65 Identities = 12/38 (31%), Positives = 21/38 (55%) Frame = -3 Query: 310 FSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFEL 197 +++I F G C+G+ FA ++K + L FEF + Sbjct: 436 YAFIPFSAGPRNCIGQQFAMNEMKVVTALCLLRFEFSV 473
>C77A1_SOLME (P37123) Cytochrome P450 77A1 (EC 1.14.-.-) (CYPLXXVIIA1)| (P-450EG6) (Fragment) Length = 499 Score = 31.2 bits (69), Expect = 0.65 Identities = 16/53 (30%), Positives = 27/53 (50%), Gaps = 2/53 (3%) Frame = -3 Query: 355 DRFAAGREEDKVAGA--FSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEF 203 DRF +GRE+ + G + FG GR C G A + + + +++ FE+ Sbjct: 414 DRFLSGREDADITGVKEVKMMPFGVGRRICPGLGMATVHVNLMLARMVQEFEW 466
>CPXQ_SACER (P48635) Cytochrome P450 113A1 (Erythromycin B/D C-12 hydroxylase)| Length = 397 Score = 31.2 bits (69), Expect = 0.65 Identities = 17/49 (34%), Positives = 24/49 (48%) Frame = -3 Query: 355 DRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNF 209 DRF R+ +G + SFG G H CLG P A L+ + ++ F Sbjct: 316 DRFDPSRK----SGGAAQFSFGHGVHFCLGAPLARLENRVALEEIIARF 360
>CP6G1_DROME (Q9V674) Cytochrome P450 6g1 (EC 1.14.-.-) (CYPVIG1) (Cyp6-like| protein) Length = 524 Score = 31.2 bits (69), Expect = 0.65 Identities = 18/48 (37%), Positives = 24/48 (50%) Frame = -3 Query: 355 DRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRN 212 +RF+ ++ VA A Y FG G H C+G LQ K LL+N Sbjct: 433 ERFSPANRKNIVAMA--YQPFGSGPHNCIGSRIGLLQSKLGLVSLLKN 478
>CP2G1_RABIT (P24461) Cytochrome P450 2G1 (EC 1.14.14.1) (CYPIIG1) (P450-NMB)| (Olfactive) Length = 494 Score = 31.2 bits (69), Expect = 0.65 Identities = 12/40 (30%), Positives = 23/40 (57%) Frame = -3 Query: 307 SYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVSP 188 +++ F G+ CLGE A +++ +T +L+NF + P Sbjct: 428 AFVPFSSGKRICLGEAMARMELFLYFTSILQNFSLHPLVP 467
>CP11A_SHEEP (P79202) Cytochrome P450 11A1, mitochondrial precursor (EC| 1.14.15.6) (CYPXIA1) (P450(SCC)) (Cholesterol side-chain cleavage enzyme) (Cholesterol desmolase) Length = 520 Score = 31.2 bits (69), Expect = 0.65 Identities = 15/48 (31%), Positives = 25/48 (52%) Frame = -3 Query: 340 GREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFEL 197 G+++D + F + FG G C+G A L++ H+L NF E+ Sbjct: 441 GKDKDLIH--FRNLGFGWGVRQCVGRRIAELEMTLFLIHILENFRVEM 486
>C28D1_DROME (Q9VMT5) Probable cytochrome P450 28d1 (EC 1.14.-.-) (CYPXXVIIID1)| Length = 502 Score = 31.2 bits (69), Expect = 0.65 Identities = 21/67 (31%), Positives = 33/67 (49%), Gaps = 4/67 (5%) Frame = -3 Query: 304 YISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVSPFP----ENDWNAMVVGIKGEV 137 + FG G C G F+ QIKA ++RNF+ + V+P E D + +KG V Sbjct: 436 FFGFGDGPRICPGMRFSLTQIKAALVEIVRNFDIK-VNPKTRKDNEIDDTYFMPALKGGV 494 Query: 136 MVNYKRR 116 +++ R Sbjct: 495 WLDFVER 501
>C13A4_CAEEL (Q27513) Putative cytochrome P450 CYP13A4 (EC 1.14.-.-)| Length = 520 Score = 31.2 bits (69), Expect = 0.65 Identities = 12/35 (34%), Positives = 21/35 (60%) Frame = -3 Query: 304 YISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFE 200 Y+ FG G C+G A ++ K + TH+L+ + F+ Sbjct: 454 YLPFGMGPRICIGMRLAMMEEKLLLTHILKKYTFD 488
>C80A1_BERST (P47195) Berbamunine synthase (EC 1.14.21.3) (Cytochrome P450 80)| (CYPLXXX) ((S)-N-methylcoclaurine oxidase [C-O phenol-coupling]) Length = 487 Score = 31.2 bits (69), Expect = 0.65 Identities = 16/43 (37%), Positives = 20/43 (46%) Frame = -3 Query: 310 FSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVSPFP 182 F +I FG GR C G P A I + L+ F +EL P Sbjct: 417 FQFIPFGSGRRICPGRPLAVRIIPLVLASLVHAFGWELPDGVP 459
>C11B2_MOUSE (P15539) Cytochrome P450 11B2, mitochondrial precursor (EC| 1.14.15.4) (EC 1.14.15.5) (CYPXIB2) (P450C11) (Steroid 11-beta-hydroxylase) (Aldosterone synthase) Length = 500 Score = 31.2 bits (69), Expect = 0.65 Identities = 12/38 (31%), Positives = 23/38 (60%) Frame = -3 Query: 313 AFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFE 200 +F +++FG G CLG A +++ + H+L+ F+ E Sbjct: 434 SFQHLAFGFGVRQCLGRRLAEVEMMLLLHHILKTFQVE 471
>CPXM_BACSU (P27632) Cytochrome P450 109 (EC 1.14.-.-) (ORF405)| Length = 405 Score = 31.2 bits (69), Expect = 0.65 Identities = 18/52 (34%), Positives = 26/52 (50%), Gaps = 9/52 (17%) Frame = -3 Query: 346 AAGREEDKVAG---------AFSYISFGGGRHGCLGEPFAYLQIKAIWTHLL 218 +A R+EDK ++ ++SFG G H CLG P A L+ + LL Sbjct: 318 SANRDEDKFCKPDCFKIDRPSYPHLSFGFGIHFCLGAPLARLEANIALSSLL 369
>CP4B1_MOUSE (Q64462) Cytochrome P450 4B1 (EC 1.14.14.1) (CYPIVB1)| Length = 511 Score = 31.2 bits (69), Expect = 0.65 Identities = 15/43 (34%), Positives = 23/43 (53%) Frame = -3 Query: 310 FSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVSPFP 182 F+++ F G C+G+ FA ++K + L FEF SP P Sbjct: 441 FAFMPFSAGPRNCIGQQFAMNEMKVVTALCLLRFEF---SPDP 480
>CP2CD_RAT (P20814) Cytochrome P450 2C13, male-specific (EC 1.14.14.1)| (CYPIIC13) (P450-G) (P-450g) (UT-5) Length = 490 Score = 31.2 bits (69), Expect = 0.65 Identities = 15/40 (37%), Positives = 24/40 (60%), Gaps = 1/40 (2%) Frame = -3 Query: 304 YISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFE-LVSP 188 +I F G+ CLGE A +++ T +L+NF+ + LV P Sbjct: 425 FIPFSAGKRMCLGESLARMELFLFLTTILQNFKLKSLVDP 464
>C76B1_HELTU (O23976) Cytochrome P450 76B1 (EC 1.14.-.-) (7-ethoxycoumarin| O-deethylase) (ECOD) (Phenylurea dealkylase) Length = 490 Score = 31.2 bits (69), Expect = 0.65 Identities = 15/43 (34%), Positives = 22/43 (51%) Frame = -3 Query: 310 FSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVSPFP 182 F I FG GR C G P A + + LL NF++++ + P Sbjct: 420 FDLIPFGAGRRICPGIPLATRMVPIMLGSLLNNFDWKIDTKVP 462
>C71C3_MAIZE (P93703) Cytochrome P450 71C3 (EC 1.14.-.-) (Benzoxazineless 5)| Length = 535 Score = 31.2 bits (69), Expect = 0.65 Identities = 13/47 (27%), Positives = 25/47 (53%) Frame = -3 Query: 310 FSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVSPFPENDW 170 F Y+ FG GR C G F ++ + +L+ +F++E+ + + W Sbjct: 463 FRYLPFGSGRRICPGANFGLATMEIMLANLMYHFDWEVPNEKEDGCW 509 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 45,791,413 Number of Sequences: 219361 Number of extensions: 822157 Number of successful extensions: 2969 Number of sequences better than 10.0: 457 Number of HSP's better than 10.0 without gapping: 2937 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 2964 length of database: 80,573,946 effective HSP length: 94 effective length of database: 59,954,012 effective search space used: 1438896288 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
