>DCNL4_BRARE (Q5RHX6) DCN1-like protein 4 (Defective in cullin neddylation|
           protein 1-like protein 4) (DCUN1 domain-containing
           protein 4)
          Length = 280

 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 23/44 (52%), Positives = 26/44 (59%)
 Frame = -3

Query: 498 NMDQWMGFLRFCNEINFPSLDNYDADQAWPLILDNFVEWLRANE 367
           N DQW   L F   IN   L NYD D AWP++LD FVEW +  E
Sbjct: 236 NKDQWCNVLEFSRTINL-DLSNYDEDGAWPVLLDEFVEWYKDRE 278

>DCNL4_HUMAN (Q92564) DCN1-like protein 4 (Defective in cullin neddylation|
           protein 1-like protein 4) (DCUN1 domain-containing
           protein 4)
          Length = 292

 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 22/41 (53%), Positives = 25/41 (60%)
 Frame = -3

Query: 498 NMDQWMGFLRFCNEINFPSLDNYDADQAWPLILDNFVEWLR 376
           N DQW   L F   IN   L NYD D AWP++LD FVEW +
Sbjct: 248 NKDQWCNVLEFSRTINL-DLSNYDEDGAWPVLLDEFVEWYK 287

>DCNL4_MOUSE (Q8CCA0) DCN1-like protein 4 (Defective in cullin neddylation|
           protein 1-like protein 4) (DCUN1 domain-containing
           protein 4)
          Length = 292

 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 21/41 (51%), Positives = 25/41 (60%)
 Frame = -3

Query: 498 NMDQWMGFLRFCNEINFPSLDNYDADQAWPLILDNFVEWLR 376
           N DQW   L F   I+   L NYD D AWP++LD FVEW +
Sbjct: 248 NKDQWCNVLEFSRTISL-DLSNYDEDGAWPVLLDEFVEWYK 287

>DCN1_USTMA (Q4PF67) Defective in cullin neddylation protein 1|
          Length = 319

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 22/41 (53%), Positives = 26/41 (63%)
 Frame = -3

Query: 492 DQWMGFLRFCNEINFPSLDNYDADQAWPLILDNFVEWLRAN 370
           D WM FL F  EIN     N+D D AWP I+D+FV W+R N
Sbjct: 270 DTWMQFLDFTKEIN-SDFSNHDFDAAWPSIIDDFVLWVRDN 309

>DCN1L_DROME (Q9VUQ8) DCN1-like protein (Defective in cullin neddylation protein|
           1-like protein)
          Length = 288

 Score = 42.7 bits (99), Expect = 5e-04
 Identities = 17/43 (39%), Positives = 28/43 (65%)
 Frame = -3

Query: 492 DQWMGFLRFCNEINFPSLDNYDADQAWPLILDNFVEWLRANEN 364
           D W   L F   I+   + NYD++ AWP+++D+FVEW + N++
Sbjct: 207 DTWNLLLDFATNID-DRMSNYDSEGAWPVLIDDFVEWCQENDH 248

>DCN1_CAEEL (Q9U3C8) Defective in cullin neddylation protein 1|
          Length = 295

 Score = 38.1 bits (87), Expect = 0.013
 Identities = 18/45 (40%), Positives = 27/45 (60%)
 Frame = -3

Query: 492 DQWMGFLRFCNEINFPSLDNYDADQAWPLILDNFVEWLRANEN*P 358
           D W  F  F   ++ P L +YD + AWP+++D FV++ R N N P
Sbjct: 235 DTWNLFWDFIL-LSKPDLSDYDDEGAWPVLIDQFVDYCRENLNYP 278

>DCNL2_MOUSE (Q8BZJ7) DCN1-like protein 2 (Defective in cullin neddylation|
           protein 2-like protein 2) (DCUN1 domain-containing
           protein 2)
          Length = 258

 Score = 37.4 bits (85), Expect = 0.023
 Identities = 18/39 (46%), Positives = 24/39 (61%)
 Frame = -3

Query: 492 DQWMGFLRFCNEINFPSLDNYDADQAWPLILDNFVEWLR 376
           D W   L F N I    L NYD + AWP+++D+FVE+ R
Sbjct: 210 DTWNLLLDFGNMIA-DDLSNYDEEGAWPVLIDDFVEYAR 247

>DCN1_YARLI (Q6C0B6) Defective in cullin neddylation protein 1|
          Length = 240

 Score = 37.0 bits (84), Expect = 0.030
 Identities = 13/24 (54%), Positives = 20/24 (83%)
 Frame = -3

Query: 447 PSLDNYDADQAWPLILDNFVEWLR 376
           PSL++YD D AWP ++D +VE+L+
Sbjct: 216 PSLESYDEDGAWPSVIDEYVEFLK 239

>DCNL2_HUMAN (Q6PH85) DCN1-like protein 2 (Defective in cullin neddylation|
           protein 2-like protein 2) (DCUN1 domain-containing
           protein 2)
          Length = 259

 Score = 36.6 bits (83), Expect = 0.039
 Identities = 17/39 (43%), Positives = 24/39 (61%)
 Frame = -3

Query: 492 DQWMGFLRFCNEINFPSLDNYDADQAWPLILDNFVEWLR 376
           D W   L F N I    + NYD + AWP+++D+FVE+ R
Sbjct: 211 DTWNLLLDFGNMIA-DDMSNYDEEGAWPVLIDDFVEYAR 248

>DCNL1_MOUSE (Q9QZ73) DCN1-like protein 1 (Defective in cullin neddylation|
           protein 1-like protein 1) (DCUN1 domain-containing
           protein 1) (Testis-specific protein 3)
          Length = 259

 Score = 35.0 bits (79), Expect = 0.11
 Identities = 16/39 (41%), Positives = 24/39 (61%)
 Frame = -3

Query: 492 DQWMGFLRFCNEINFPSLDNYDADQAWPLILDNFVEWLR 376
           D W   L F + I    + NYD + AWP+++D+FVE+ R
Sbjct: 211 DTWNLLLDFSSMIA-DDMSNYDEEGAWPVLIDDFVEFAR 248

>DCNL1_HUMAN (Q96GG9) DCN1-like protein 1 (Defective in cullin neddylation|
           protein 1-like protein 1) (DCUN1 domain-containing
           protein 1) (Squamous cell carcinoma-related oncogene)
          Length = 259

 Score = 34.7 bits (78), Expect = 0.15
 Identities = 16/39 (41%), Positives = 23/39 (58%)
 Frame = -3

Query: 492 DQWMGFLRFCNEINFPSLDNYDADQAWPLILDNFVEWLR 376
           D W   L F   I    + NYD + AWP+++D+FVE+ R
Sbjct: 211 DTWNLLLDFSTMIA-DDMSNYDEEGAWPVLIDDFVEFAR 248

>DCNL1_CHICK (Q5ZKU1) DCN1-like protein 1 (Defective in cullin neddylation|
           protein 1-like protein 1) (DCUN1 domain-containing
           protein 1)
          Length = 259

 Score = 34.7 bits (78), Expect = 0.15
 Identities = 16/39 (41%), Positives = 23/39 (58%)
 Frame = -3

Query: 492 DQWMGFLRFCNEINFPSLDNYDADQAWPLILDNFVEWLR 376
           D W   L F   I    + NYD + AWP+++D+FVE+ R
Sbjct: 211 DTWNLLLDFSTMIA-DDMSNYDEEGAWPVLIDDFVEFAR 248

>DCN1_CAEBR (Q60YT5) Defective in cullin neddylation protein 1|
          Length = 292

 Score = 34.3 bits (77), Expect = 0.19
 Identities = 18/49 (36%), Positives = 25/49 (51%)
 Frame = -3

Query: 492 DQWMGFLRFCNEINFPSLDNYDADQAWPLILDNFVEWLRANEN*PSCTR 346
           D W  F  F   +    L +YD + AWP+++D FV+  R N N P   R
Sbjct: 233 DTWNLFWDFI-VLGKEDLSDYDEEGAWPVLIDQFVDHCRENLNYPKPLR 280

>DCN1_CRYNE (Q5KHV1) Defective in cullin neddylation protein 1|
          Length = 279

 Score = 33.1 bits (74), Expect = 0.43
 Identities = 15/39 (38%), Positives = 22/39 (56%)
 Frame = -3

Query: 492 DQWMGFLRFCNEINFPSLDNYDADQAWPLILDNFVEWLR 376
           D W   + F   I+      YD D AWP ++D+FVE++R
Sbjct: 236 DTWALLVDFARGID-KDFKEYDEDGAWPSMIDDFVEYVR 273

>DCN1_ASHGO (Q750Y3) Defective in cullin neddylation protein 1|
          Length = 256

 Score = 32.7 bits (73), Expect = 0.56
 Identities = 15/43 (34%), Positives = 24/43 (55%), Gaps = 4/43 (9%)
 Frame = -3

Query: 492 DQWMGFLRFCNEINFPS----LDNYDADQAWPLILDNFVEWLR 376
           D W  F RF     FP     L++Y+   +WPL++D + EW++
Sbjct: 211 DTWDMFPRFAQR--FPDDTELLEHYNELASWPLVIDEYYEWVK 251

>DCN1_SCHPO (Q8WZK4) Defective in cullin neddylation protein 1|
          Length = 251

 Score = 32.0 bits (71), Expect = 0.95
 Identities = 11/24 (45%), Positives = 16/24 (66%)
 Frame = -3

Query: 447 PSLDNYDADQAWPLILDNFVEWLR 376
           P+  NYD + AWP ++D FV + R
Sbjct: 219 PNCSNYDFEGAWPTLIDEFVSYYR 242

>DCN1_MAGGR (Q52DM9) Defective in cullin neddylation protein 1|
          Length = 281

 Score = 30.8 bits (68), Expect = 2.1
 Identities = 15/40 (37%), Positives = 21/40 (52%), Gaps = 1/40 (2%)
 Frame = -3

Query: 492 DQWMGFLRFCNEINFPS-LDNYDADQAWPLILDNFVEWLR 376
           D W   L F  +    S L  +  + +WP ++D FVEWLR
Sbjct: 228 DMWNQTLDFAVKSTADSTLSFWTPEGSWPSVIDGFVEWLR 267

>DCN1_CANGA (Q6FJR2) Defective in cullin neddylation protein 1|
          Length = 273

 Score = 30.8 bits (68), Expect = 2.1
 Identities = 17/42 (40%), Positives = 21/42 (50%), Gaps = 4/42 (9%)
 Frame = -3

Query: 492 DQWMGFLRFCNEINFPSLD----NYDADQAWPLILDNFVEWL 379
           D W   L F  +  FPSLD     Y+   AWP  +D F E+L
Sbjct: 228 DTWQMLLLFFKK--FPSLDAIKTEYNEADAWPYTIDEFYEYL 267

>TAXB1_RAT (Q66HA4) Tax1-binding protein 1 homolog (Liver regeneration-related|
           protein LRRG004)
          Length = 813

 Score = 30.4 bits (67), Expect = 2.8
 Identities = 16/41 (39%), Positives = 22/41 (53%)
 Frame = +2

Query: 74  FKTSRKLHALETTHLQSH*KYKYRECRHKILDDDPAKCFKY 196
           F  S K H  E T   +    KY +C+ ++L D+ AKC KY
Sbjct: 517 FDMSAKDHVCEVTKEMAEKVEKYNKCK-QLLQDEKAKCNKY 556

>HANG_DROME (Q9VXG1) Zinc finger protein hangover|
          Length = 1959

 Score = 30.0 bits (66), Expect = 3.6
 Identities = 18/44 (40%), Positives = 21/44 (47%), Gaps = 2/44 (4%)
 Frame = +2

Query: 50   EQHMPTCSFK--TSRKLHALETTHLQSH*KYKYRECRHKILDDD 175
            + H PTC+ K  TS   H  +   L SH   K    RHK  DDD
Sbjct: 1230 DNHTPTCNRKPITSTGAHQQQDGQLHSHHTAKRTIFRHKTGDDD 1273

>DCN1_CANAL (Q5ADL9) Defective in cullin neddylation protein 1|
          Length = 304

 Score = 29.6 bits (65), Expect = 4.7
 Identities = 15/41 (36%), Positives = 20/41 (48%), Gaps = 3/41 (7%)
 Frame = -3

Query: 492 DQWMGFLRFCNEINFPS---LDNYDADQAWPLILDNFVEWL 379
           D W  F  F  EI         +YD   AWP ++D F+E+L
Sbjct: 258 DSWSMFYLFFKEIVLIDPIKFKDYDEMAAWPSVVDEFLEYL 298

>CHD3_HUMAN (Q12873) Chromodomain helicase-DNA-binding protein 3 (EC 3.6.1.-)|
           (ATP-dependent helicase CHD3) (CHD-3) (Mi-2 autoantigen
           240 kDa protein) (Mi2-alpha) (Zinc-finger helicase)
           (hZFH)
          Length = 2000

 Score = 29.6 bits (65), Expect = 4.7
 Identities = 15/32 (46%), Positives = 19/32 (59%)
 Frame = +2

Query: 131 KYKYRECRHKILDDDPAKCFKY*KVKSKLQGD 226
           K  Y   R  I+ +DPA+  KY K K +LQGD
Sbjct: 677 KQSYWRHRELIMGEDPAQPRKYKKKKKELQGD 708

>CD180_HUMAN (Q99467) CD180 antigen precursor (Lymphocyte antigen 64)|
           (Radioprotective 105 kDa protein)
          Length = 661

 Score = 29.3 bits (64), Expect = 6.2
 Identities = 29/124 (23%), Positives = 52/124 (41%), Gaps = 3/124 (2%)
 Frame = +3

Query: 48  KNNICQHV---HLRLPENCMLLKLHTYKAIENTNIENVDIKF*MMTLLSVSSIKK*KANY 218
           K N+ Q V    + +  +C LL +          + +VD+    +T  S+ S+   K  Y
Sbjct: 488 KTNLLQTVGSLEVLILSSCGLLSIDQQAFHSLGKMSHVDLSHNSLTCDSIDSLSHLKGIY 547

Query: 219 KAIDNF*NQTLNTAVTNELDLHPPKFSKVISEYCI*IASSPPLEYKRANFHLLLTIQQNC 398
                     LN A  N +++  P+   ++S+      S  PL+   +N H L   ++N 
Sbjct: 548 ----------LNLAA-NSINIISPRLLPILSQQSTINLSHNPLDCTCSNIHFLTWYKENL 596

Query: 399 LKLK 410
            KL+
Sbjct: 597 HKLE 600

>CBBYP_RALEU (Q04541) Protein cbbY, plasmid|
          Length = 254

 Score = 29.3 bits (64), Expect = 6.2
 Identities = 11/23 (47%), Positives = 16/23 (69%)
 Frame = -1

Query: 329 NLNAILRNHLGEFWRMQIKLVCD 261
           NL+A+L+ HLG  WR +   +CD
Sbjct: 125 NLDALLQAHLGADWRGRFAAICD 147

>YNN1_CAEEL (Q03605) Hypothetical RING finger protein T02C1.1 in chromosome III|
          Length = 160

 Score = 28.9 bits (63), Expect = 8.1
 Identities = 14/56 (25%), Positives = 26/56 (46%)
 Frame = +3

Query: 60  CQHVHLRLPENCMLLKLHTYKAIENTNIENVDIKF*MMTLLSVSSIKK*KANYKAI 227
           C   HL + E C L + HT   I N  +E++ + +     +S    ++ K+  K +
Sbjct: 31  CIESHLNINEKCPLCRAHTGNPIRNRQLESLTMSYVSSRNISTEYYERMKSYQKKL 86


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 70,595,802
Number of Sequences: 219361
Number of extensions: 1356265
Number of successful extensions: 2814
Number of sequences better than 10.0: 25
Number of HSP's better than 10.0 without gapping: 2764
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2813
length of database: 80,573,946
effective HSP length: 104
effective length of database: 57,760,402
effective search space used: 3581144924
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)