ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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更新日:2016年5月1日

Clone Information

BLAST Search Result

Clone Name rbart54a01
Clone Library Name barley_pub

No. Definition Score
(bits)
E
Value
1NADO1_ORYSA (Q7G764) Probable NAD(P)H-dependent oxidoreductase 1... 189 6e-48
2NADO2_ORYSA (Q7G765) Probable NAD(P)H-dependent oxidoreductase 2... 181 2e-45
36DCS_SOYBN (P26690) NAD(P)H dependent 6'-deoxychalcone synthase ... 108 8e-24
4ALDR_HORVU (P23901) Aldose reductase (EC 1.1.1.21) (AR) (Aldehyd... 78 1e-14
5S6PD_MALDO (P28475) NADP-dependent D-sorbitol-6-phosphate dehydr... 69 9e-12
6AK1CD_MOUSE (Q8VC28) Aldo-keto reductase family 1 member C13 (EC... 68 2e-11
7AK1E1_MOUSE (Q9DCT1) Aldo-keto reductase family 1 member E1 (EC ... 66 6e-11
8ALD1_MOUSE (P21300) Aldose reductase-related protein 1 (EC 1.1.1... 64 3e-10
9DHB5_MOUSE (P70694) Estradiol 17 beta-dehydrogenase 5 (EC 1.1.1.... 63 5e-10
10CRO_RANCA (P17264) Rho crystallin 63 6e-10
11CRO_RANTE (P02532) Rho crystallin 62 1e-09
12XYL1_PICST (P31867) NAD(P)H-dependent D-xylose reductase (EC 1.1... 62 1e-09
13ALD2_CRIGR (O08782) Aldose reductase-related protein 2 (EC 1.1.1... 62 1e-09
14AK1BA_HUMAN (O60218) Aldo-keto reductase family 1 member B10 (EC... 62 1e-09
15AK1C4_MACFU (Q95JH4) Aldo-keto reductase family 1 member C4 (EC ... 61 2e-09
16AK1C4_MACFA (Q95JH5) Aldo-keto reductase family 1 member C4 (EC ... 61 2e-09
17AK1C2_HUMAN (P52895) Aldo-keto reductase family 1 member C2 (EC ... 61 2e-09
18AK1C1_MACFU (Q95JH6) Aldo-keto reductase family 1 member C1 homo... 61 2e-09
19AK1C1_HUMAN (Q04828) Aldo-keto reductase family 1 member C1 (EC ... 61 2e-09
20AK1C1_PONPY (Q5REQ0) Aldo-keto reductase family 1 member C1 homo... 60 3e-09
21XYL1_ASPNG (Q9P8R5) NAD(P)H-dependent D-xylose reductase (EC 1.1... 60 3e-09
22ALDR_RAT (P07943) Aldose reductase (EC 1.1.1.21) (AR) (Aldehyde ... 60 5e-09
23AK1C3_PONPY (Q5R7C9) Aldo-keto reductase family 1 member C3 homo... 59 7e-09
24AK1C1_MACFA (Q95JH7) Aldo-keto reductase family 1 member C1 homo... 59 7e-09
25ALDR_PIG (P80276) Aldose reductase (EC 1.1.1.21) (AR) (Aldehyde ... 59 9e-09
26ALDR_MOUSE (P45376) Aldose reductase (EC 1.1.1.21) (AR) (Aldehyd... 59 9e-09
27AK1D1_MOUSE (Q8VCX1) 3-oxo-5-beta-steroid 4-dehydrogenase (EC 1.... 58 2e-08
28AK1C4_HUMAN (P17516) Aldo-keto reductase family 1 member C4 (EC ... 58 2e-08
29AK1D1_HUMAN (P51857) 3-oxo-5-beta-steroid 4-dehydrogenase (EC 1.... 58 2e-08
30DKGA_ECOLI (Q46857) 2,5-diketo-D-gluconic acid reductase A (EC 1... 58 2e-08
31DKGA_ECO57 (Q8XBT6) 2,5-diketo-D-gluconic acid reductase A (EC 1... 58 2e-08
32PGFS2_BOVIN (P52897) Prostaglandin-F synthase 2 (EC 1.1.1.188) (... 57 3e-08
33PGFS1_BOVIN (P05980) Prostaglandin-F synthase 1 (EC 1.1.1.188) (... 57 3e-08
34PE2R_RABIT (P80508) Prostaglandin-E(2) 9-reductase (EC 1.1.1.189... 57 3e-08
35ALDR_RABIT (P15122) Aldose reductase (EC 1.1.1.21) (AR) (Aldehyd... 57 3e-08
36ALDR_HUMAN (P15121) Aldose reductase (EC 1.1.1.21) (AR) (Aldehyd... 57 3e-08
37AK1D1_RABIT (Q9TV64) 3-oxo-5-beta-steroid 4-dehydrogenase (EC 1.... 57 3e-08
38AK1C3_HUMAN (P42330) Aldo-keto reductase family 1 member C3 (EC ... 57 4e-08
39ALD2_MOUSE (P45377) Aldose reductase-related protein 2 (EC 1.1.1... 57 4e-08
40ALDR_BOVIN (P16116) Aldose reductase (EC 1.1.1.21) (AR) (Aldehyd... 55 1e-07
41AK1A1_MOUSE (Q9JII6) Alcohol dehydrogenase [NADP+] (EC 1.1.1.2) ... 55 1e-07
42AK1A1_RAT (P51635) Alcohol dehydrogenase [NADP+] (EC 1.1.1.2) (A... 55 1e-07
43AK1A1_PIG (P50578) Alcohol dehydrogenase [NADP+] (EC 1.1.1.2) (A... 55 2e-07
44XYL1_PACTA (P78736) NAD(P)H-dependent D-xylose reductase (EC 1.1... 54 2e-07
45AK1A1_HUMAN (P14550) Alcohol dehydrogenase [NADP+] (EC 1.1.1.2) ... 54 2e-07
46AK1CD_MESAU (P82809) Aldo-keto reductase family 1 member C13 (EC... 54 3e-07
47XYL2_CANTR (P87039) NADPH-dependent D-xylose reductase II,III (E... 53 5e-07
48DKGA_SALTY (Q8ZM06) 2,5-diketo-D-gluconic acid reductase A (EC 1... 53 5e-07
49DDBX_BOVIN (P52898) Dihydrodiol dehydrogenase 3 (EC 1.-.-.-) (Pr... 53 6e-07
50DKGA_SALTI (P58744) 2,5-diketo-D-gluconic acid reductase A (EC 1... 52 8e-07
51DKGA_YERPE (Q8ZI40) 2,5-diketo-D-gluconic acid reductase A (EC 1... 52 1e-06
52DKGA_CORSC (P06632) 2,5-diketo-D-gluconic acid reductase A (EC 1... 52 1e-06
53XYL1_CANTR (O13283) NAD(P)H-dependent D-xylose reductase I,II (E... 52 1e-06
54XYL1_CANTE (O74237) NAD(P)H-dependent D-xylose reductase (EC 1.1... 51 2e-06
55YOF5_CAEEL (Q09632) Probable oxidoreductase ZK1290.5 in chromoso... 51 2e-06
56P100_LEIMA (P22045) Probable reductase (EC 1.1.-.-) 51 2e-06
57XYL1_CANSH (Q9P430) NAD(P)H-dependent D-xylose reductase (EC 1.1... 51 2e-06
58AKC1H_RAT (P51652) Aldo-keto reductase family 1 member C18 (EC 1... 50 3e-06
59XYL1_PICGU (O94735) NADPH-dependent D-xylose reductase (EC 1.1.1... 50 3e-06
60XYL1_CANPA (Q6Y0Z3) NADH-dependent D-xylose reductase (EC 1.1.1.... 50 3e-06
61DKGB_CORSS (P15339) 2,5-diketo-D-gluconic acid reductase B (EC 1... 49 7e-06
62MORA_PSEPU (Q02198) Morphine 6-dehydrogenase (EC 1.1.1.218) (Nal... 49 1e-05
63AKC1H_MOUSE (Q8K023) Aldo-keto reductase family 1 member C18 (EC... 47 3e-05
64XYL1_TRIRE (Q876L8) NAD(P)H-dependent D-xylose reductase (EC 1.1... 46 8e-05
65XYL1_KLULA (P49378) NAD(P)H-dependent D-xylose reductase (EC 1.1... 45 2e-04
66GRE3_YEAST (P38715) NADPH-dependent aldose reductase GRE3 (EC 1.... 44 3e-04
67DTDH_MUCMU (Q01213) 4-dihydromethyl-trisporate dehydrogenase (EC... 44 4e-04
68YPR1_YEAST (Q12458) Putative reductase 1 (EC 1.1.1.-) 43 5e-04
69AK1D1_RAT (P31210) 3-oxo-5-beta-steroid 4-dehydrogenase (EC 1.3.... 43 7e-04
70YDG7_SCHPO (Q10494) Probable oxidoreductase C26F1.07 in chromoso... 42 0.001
71GCY_YEAST (P14065) GCY protein (EC 1.1.1.-) 42 0.001
72ALDX_SPOSA (P27800) Aldehyde reductase 1 (EC 1.1.1.2) (Aldehyde ... 39 0.012
73DKGB_ECOLI (P30863) 2,5-diketo-D-gluconic acid reductase B (EC 1... 38 0.021
74DKGB_ECO57 (Q8X7Z7) 2,5-diketo-D-gluconic acid reductase B (EC 1... 38 0.021
75YEAE_ECOLI (P76234) Hypothetical protein yeaE 36 0.062
76DKGB_SALTY (Q8ZRM7) 2,5-diketo-D-gluconic acid reductase B (EC 1... 35 0.18
77YDBC_ECOLI (P25906) Putative oxidoreductase ydbC (EC 1.-.-.-) 34 0.23
78YJ66_YEAST (P47137) Probable oxidoreductase YJR096W (EC 1.-.-.-) 34 0.23
79MOVP_TAV (P23626) Movement protein (MP) (Protein 3A) 33 0.68
80DXS_CHLMU (Q9PK62) 1-deoxy-D-xylulose-5-phosphate synthase (EC 2... 33 0.68
81ARA1_YEAST (P38115) D-arabinose dehydrogenase [NAD(P)+] heavy ch... 33 0.68
82GNDS_MOUSE (Q03385) Ral guanine nucleotide dissociation stimulat... 32 0.89
83DKGB_YERPE (Q8ZH36) 2,5-diketo-D-gluconic acid reductase B (EC 1... 32 1.2
84MIB2_HUMAN (Q96AX9) Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (... 32 1.2
85MURA1_STRR6 (Q8DNE8) UDP-N-acetylglucosamine 1-carboxyvinyltrans... 32 1.2
86MURA1_STRPN (Q97NQ4) UDP-N-acetylglucosamine 1-carboxyvinyltrans... 32 1.2
87MOVP_PSVJ (P22117) Movement protein (MP) (Protein 3A) 32 1.2
88RPOA1_THECE (P31813) DNA-directed RNA polymerase subunit A' (EC ... 32 1.2
89ALGC_PSEPK (Q88C93) Phosphomannomutase/phosphoglucomutase (EC 5.... 31 2.0
90SYFB_METKA (Q8TX56) Phenylalanyl-tRNA synthetase beta chain (EC ... 31 2.6
91GATE_PYRFU (Q8U0W9) Glutamyl-tRNA(Gln) amidotransferase subunit ... 31 2.6
92HIS82_BURS3 (Q39CT7) Histidinol-phosphate aminotransferase 2 (EC... 31 2.6
93GS69_BACSU (P80874) General stress protein 69 (EC 1.1.1.-) (GSP6... 31 2.6
94LNT_RHOPA (P61036) Apolipoprotein N-acyltransferase (EC 2.3.1.-)... 31 2.6
95GUAA_ANAMM (Q5P9L5) GMP synthase [glutamine-hydrolyzing] (EC 6.3... 31 2.6
96GNDS_HUMAN (Q12967) Ral guanine nucleotide dissociation stimulat... 30 3.4
97MURA1_BACSU (P70965) UDP-N-acetylglucosamine 1-carboxyvinyltrans... 30 3.4
98THIC2_ARATH (Q9FIK7) Probable acetyl-CoA acetyltransferase, cyto... 30 3.4
99AK1A1_CRIGR (O70473) Alcohol dehydrogenase [NADP+] (EC 1.1.1.2) ... 30 3.4
100YEC4_EBV (P03235) Hypothetical protein EC-RF4 30 4.4
101MURA3_SYMTH (Q67J65) UDP-N-acetylglucosamine 1-carboxyvinyltrans... 30 4.4
102TREF1_MOUSE (Q8BXJ2) Transcriptional-regulating factor 1 (Transc... 30 5.8
103DUT_ASHGO (Q74ZF0) Deoxyuridine 5'-triphosphate nucleotidohydrol... 29 7.6
104ATC1_YARLI (O43108) Calcium-transporting ATPase 1 (EC 3.6.3.8) (... 29 7.6
105MOVP_CMVTR (Q83252) Movement protein (MP) (Protein 3A) 29 7.6
106MOVP_CMVS (Q66134) Movement protein (MP) (Protein 3A) 29 7.6
107MOVP_CMVKI (Q06938) Movement protein (MP) (Protein 3A) 29 7.6
108SWD3_YEAST (P38123) COMPASS component SWD3 (Complex proteins ass... 29 7.6
109PCNB_ECOLI (P0ABF1) Poly(A) polymerase (EC 2.7.7.19) (PAP) (Plas... 29 9.9
110PCNB_ECOL6 (P0ABF2) Poly(A) polymerase (EC 2.7.7.19) (PAP) (Plas... 29 9.9
111PCNB_ECO57 (P0ABF3) Poly(A) polymerase (EC 2.7.7.19) (PAP) (Plas... 29 9.9
112ARLY_LISIN (Q929S8) Argininosuccinate lyase (EC 4.3.2.1) (Argino... 29 9.9
113PPS1_BACSU (P39845) Peptide synthetase 1 29 9.9
114YCCK_BACSU (P46905) Hypothetical oxidoreductase yccK (EC 1.-.-.-) 29 9.9
115Y2006_MYCTU (Q10850) Hypothetical glycosyl hydrolase Rv2006/MT20... 29 9.9

>NADO1_ORYSA (Q7G764) Probable NAD(P)H-dependent oxidoreductase 1 (EC 1.1.1.-)|
          Length = 321

 Score =  189 bits (479), Expect = 6e-48
 Identities = 82/127 (64%), Positives = 109/127 (85%)
 Frame = -1

Query: 546 QQRKLREFCRGKGIQLCAYSPLGAKGTHWGSDAVMDAGVLQDIAASRGKSVAQVCLRWVY 367
           QQR LRE CR +G+QLC YSPLGAKGT WGS AVMD+GVLQ+IA ++GK++AQ+CLRW+Y
Sbjct: 195 QQRTLREVCRREGVQLCGYSPLGAKGTPWGSAAVMDSGVLQEIAGAKGKTLAQICLRWLY 254

Query: 366 EQGDCLIVKSFDEARMRENLDVDGWELTEEERRRIAEIPQRKINLGKRYVSDHGPYKSLE 187
           EQGD L+VK+++E RM+ENLD+  WELT+EER RI+++PQ +   G  ++SDHGPYKS+E
Sbjct: 255 EQGDVLLVKTYNEKRMKENLDIFNWELTDEERERISQLPQLRGLPGLEFISDHGPYKSVE 314

Query: 186 ELWDGEI 166
           +LWDG++
Sbjct: 315 DLWDGDV 321



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>NADO2_ORYSA (Q7G765) Probable NAD(P)H-dependent oxidoreductase 2 (EC 1.-.-.-)|
          Length = 322

 Score =  181 bits (458), Expect = 2e-45
 Identities = 80/125 (64%), Positives = 106/125 (84%)
 Frame = -1

Query: 546 QQRKLREFCRGKGIQLCAYSPLGAKGTHWGSDAVMDAGVLQDIAASRGKSVAQVCLRWVY 367
           QQR LRE CR +G+QLC YSPLGAKGT WGS AVMD+GVL DIA ++GK++AQ+CLRW+Y
Sbjct: 197 QQRTLREVCRREGVQLCGYSPLGAKGTPWGSAAVMDSGVLHDIAQTKGKTLAQICLRWMY 256

Query: 366 EQGDCLIVKSFDEARMRENLDVDGWELTEEERRRIAEIPQRKINLGKRYVSDHGPYKSLE 187
           EQGD L+VK+++E RM+ENLD+  WELTEEER +I+++PQ++   G ++V D+GPYK +E
Sbjct: 257 EQGDVLLVKTYNENRMKENLDIFDWELTEEERDKISKLPQQRGLTGMQFVCDNGPYKCVE 316

Query: 186 ELWDG 172
           +LWDG
Sbjct: 317 DLWDG 321



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>6DCS_SOYBN (P26690) NAD(P)H dependent 6'-deoxychalcone synthase (EC 2.3.1.170)|
          Length = 315

 Score =  108 bits (271), Expect = 8e-24
 Identities = 60/128 (46%), Positives = 84/128 (65%), Gaps = 1/128 (0%)
 Frame = -1

Query: 546 QQRKLREFCRGKGIQLCAYSPLGAKGTHWGSDAVMDAGVLQDIAASRGKSVAQVCLRWVY 367
           QQ+KLREFC+  GI + A+SPL  KG   G + VM+  VL++IA + GKS+AQV LRW+Y
Sbjct: 197 QQKKLREFCKENGIIVTAFSPL-RKGASRGPNEVMENDVLKEIAEAHGKSIAQVSLRWLY 255

Query: 366 EQGDCLIVKSFDEARMRENLDVDGWELTEEERRRIAEIPQRKINLGKRYVSDHGPYK-SL 190
           EQG   + KS+D+ RM +NL +  W LTE++  +I++I Q       R +S  GP K  L
Sbjct: 256 EQGVTFVPKSYDKERMNQNLHIFDWALTEQDHHKISQISQ------SRLIS--GPTKPQL 307

Query: 189 EELWDGEI 166
            +LWD +I
Sbjct: 308 ADLWDDQI 315



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>ALDR_HORVU (P23901) Aldose reductase (EC 1.1.1.21) (AR) (Aldehyde reductase)|
          Length = 320

 Score = 78.2 bits (191), Expect = 1e-14
 Identities = 41/126 (32%), Positives = 71/126 (56%), Gaps = 3/126 (2%)
 Frame = -1

Query: 537 KLREFCRGKGIQLCAYSPLGAKGTHWGSDAVMDAGVLQDIAASRGKSVAQVCLRWVYEQG 358
           K+ E C+  GI + AYSPLG+   +   D V++      +A    K+  QV ++W  ++G
Sbjct: 199 KIFEACKKHGIHVTAYSPLGSSEKNLAHDPVVEK-----VANKLNKTPGQVLIKWALQRG 253

Query: 357 DCLIVKSFDEARMRENLDVDGWELTEEERRRIAEI-PQRKINLGKRYV--SDHGPYKSLE 187
             +I KS  + R++EN+ V GWE+ EE+ + +  I  ++++  G+       HGPY+S  
Sbjct: 254 TSVIPKSSKDERIKENIQVFGWEIPEEDFKVLCSIKDEKRVLTGEELFVNKTHGPYRSAA 313

Query: 186 ELWDGE 169
           ++WD E
Sbjct: 314 DVWDHE 319



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>S6PD_MALDO (P28475) NADP-dependent D-sorbitol-6-phosphate dehydrogenase (EC|
           1.1.1.200) (Aldose-6-phosphate reductase [NADPH])
           (NADP-S6PDH)
          Length = 310

 Score = 68.9 bits (167), Expect = 9e-12
 Identities = 38/104 (36%), Positives = 63/104 (60%), Gaps = 3/104 (2%)
 Frame = -1

Query: 546 QQRKLREFCRGKGIQLCAYSPLGAKGTH---WGSDAVMDAGVLQDIAASRGKSVAQVCLR 376
           Q+  L +FC   G+   A++PLG    +   +GS + +D  VL D+A   GKSVAQ+CLR
Sbjct: 191 QRDSLVKFCMKHGVLPTAHTPLGGAAANKDMFGSVSPLDDPVLNDVAKKYGKSVAQICLR 250

Query: 375 WVYEQGDCLIVKSFDEARMRENLDVDGWELTEEERRRIAEIPQR 244
           W  ++   +I KS    R++ENL+V  ++L++E+ + I  I ++
Sbjct: 251 WGIQRKTAVIPKSSKIQRLKENLEVLEFQLSDEDMQLIYSIDRK 294



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>AK1CD_MOUSE (Q8VC28) Aldo-keto reductase family 1 member C13 (EC 1.1.1.-)|
          Length = 323

 Score = 67.8 bits (164), Expect = 2e-11
 Identities = 41/124 (33%), Positives = 67/124 (54%), Gaps = 4/124 (3%)
 Frame = -1

Query: 543 QRKLREFCRGKGIQLCAYSPLGAKG-THW---GSDAVMDAGVLQDIAASRGKSVAQVCLR 376
           QRKL ++C  K I L AY  LG +    W    S  +++  VL D+A    +S A + LR
Sbjct: 199 QRKLLDYCESKDIVLVAYGALGTQRYKEWVDQNSPVLLNDPVLCDVAKKNKRSPALIALR 258

Query: 375 WVYEQGDCLIVKSFDEARMRENLDVDGWELTEEERRRIAEIPQRKINLGKRYVSDHGPYK 196
           ++ ++G   + +SF E  MRENL V G++L+ E+ + +  + +    L   ++ DH  Y 
Sbjct: 259 YLIQRGIVPLAQSFKENEMRENLQVFGFQLSPEDMKTLDGLNKNFRYLPAEFLVDHPEYP 318

Query: 195 SLEE 184
            +EE
Sbjct: 319 FVEE 322



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>AK1E1_MOUSE (Q9DCT1) Aldo-keto reductase family 1 member E1 (EC 1.1.1.-)|
          Length = 301

 Score = 66.2 bits (160), Expect = 6e-11
 Identities = 35/97 (36%), Positives = 57/97 (58%)
 Frame = -1

Query: 543 QRKLREFCRGKGIQLCAYSPLGAKGTHWGSDAVMDAGVLQDIAASRGKSVAQVCLRWVYE 364
           Q+KL +FC  + + + AY PLG  G   G   +MD  V++ IA   GKS AQ+ +R+  +
Sbjct: 184 QKKLIDFCHKRNVSVTAYRPLGGSG---GGFHLMDDTVIRKIAKKHGKSPAQILIRFQIQ 240

Query: 363 QGDCLIVKSFDEARMRENLDVDGWELTEEERRRIAEI 253
           +   +I KS   +R+REN+ V  +ELTE++   +  +
Sbjct: 241 RNLIVIPKSVTPSRIRENIQVFDFELTEKDMEELLSL 277



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>ALD1_MOUSE (P21300) Aldose reductase-related protein 1 (EC 1.1.1.21) (AR)|
           (Aldehyde reductase) (VAS deferens androgen-dependent
           protein) (MVDP) (Aldo-keto reductase family 1 member B7)
          Length = 315

 Score = 63.9 bits (154), Expect = 3e-10
 Identities = 36/97 (37%), Positives = 59/97 (60%), Gaps = 3/97 (3%)
 Frame = -1

Query: 543 QRKLREFCRGKGIQLCAYSPLGAKGTHWGSD---AVMDAGVLQDIAASRGKSVAQVCLRW 373
           Q KL ++C+ KGI + AYSPLG+    +       VM+   +++IAA   K+VAQV +R+
Sbjct: 192 QEKLIQYCQSKGIAVTAYSPLGSPDRPYAKPEDPVVMEIPKIKEIAAKHKKTVAQVLIRF 251

Query: 372 VYEQGDCLIVKSFDEARMRENLDVDGWELTEEERRRI 262
             ++   +I KS   +R++ENL V  ++L+EE+   I
Sbjct: 252 HVQRNVVVIPKSVTPSRIQENLQVFDFQLSEEDMAAI 288



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>DHB5_MOUSE (P70694) Estradiol 17 beta-dehydrogenase 5 (EC 1.1.1.-)|
           (17-beta-HSD 5)
          Length = 323

 Score = 63.2 bits (152), Expect = 5e-10
 Identities = 39/114 (34%), Positives = 64/114 (56%), Gaps = 4/114 (3%)
 Frame = -1

Query: 543 QRKLREFCRGKGIQLCAYSPLGA-KGTHW---GSDAVMDAGVLQDIAASRGKSVAQVCLR 376
           Q KL +FCR K I L AYS LG+ +   W    S  ++D  VL  +A    ++ A + LR
Sbjct: 199 QGKLLDFCRSKDIVLVAYSALGSHREKQWVDQSSPVLLDNPVLGSMAKKYNRTPALIALR 258

Query: 375 WVYEQGDCLIVKSFDEARMRENLDVDGWELTEEERRRIAEIPQRKINLGKRYVS 214
           +  ++G  ++ KSF E R++EN+ V  ++LT E+ + + +     +N   RY+S
Sbjct: 259 YQLQRGVVVLAKSFSEKRIKENMQVFEFQLTSEDMKVLDD-----LNKNIRYIS 307



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>CRO_RANCA (P17264) Rho crystallin|
          Length = 323

 Score = 62.8 bits (151), Expect = 6e-10
 Identities = 39/125 (31%), Positives = 68/125 (54%), Gaps = 5/125 (4%)
 Frame = -1

Query: 543 QRKLREFCRGKGIQLCAYSPLGA-KGTHW---GSDAVMDAGVLQDIAASRGKSVAQVCLR 376
           Q KL  +C+ K I L  YS LG+ +  +W       ++D  +L  IAA   ++ A+V +R
Sbjct: 199 QNKLHSYCKSKDIVLVTYSVLGSHRDRNWVDLSLPVLLDDPILNKIAAKYNRTSAEVAMR 258

Query: 375 WVYEQGDCLIVKSFDEARMRENLDVDGWELTEEERRRIAEIPQRKINLGK-RYVSDHGPY 199
           ++ ++G  ++ KSF  AR+++NL V  +EL  E+ + +  +  R ++ G  R V  H  Y
Sbjct: 259 FILQKGIVVLAKSFTPARIKQNLGVFEFELKPEDMKTLESL-DRNLHYGPFREVKQHPEY 317

Query: 198 KSLEE 184
              +E
Sbjct: 318 PFHDE 322



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>CRO_RANTE (P02532) Rho crystallin|
          Length = 323

 Score = 62.0 bits (149), Expect = 1e-09
 Identities = 37/125 (29%), Positives = 68/125 (54%), Gaps = 5/125 (4%)
 Frame = -1

Query: 543 QRKLREFCRGKGIQLCAYSPLGA-KGTHW---GSDAVMDAGVLQDIAASRGKSVAQVCLR 376
           Q KL  +C+ K I L  YS LG+ +  +W       ++D  +L  +AA   ++ A++ +R
Sbjct: 199 QNKLHSYCKSKDIVLVTYSVLGSHRDRNWVDLSLPVLLDDPILNKVAAKYNRTSAEIAMR 258

Query: 375 WVYEQGDCLIVKSFDEARMRENLDVDGWELTEEERRRIAEIPQRKINLGK-RYVSDHGPY 199
           ++ ++G  ++ KSF  AR+++NL V  +EL  E+ + +  +  R ++ G  R V  H  Y
Sbjct: 259 FILQKGIVVLAKSFTPARIKQNLGVFEFELKPEDMKSLESL-DRNLHYGPFREVKQHPEY 317

Query: 198 KSLEE 184
              +E
Sbjct: 318 PFHDE 322



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>XYL1_PICST (P31867) NAD(P)H-dependent D-xylose reductase (EC 1.1.1.-) (XR)|
          Length = 318

 Score = 62.0 bits (149), Expect = 1e-09
 Identities = 40/112 (35%), Positives = 61/112 (54%), Gaps = 7/112 (6%)
 Frame = -1

Query: 546 QQRKLREFCRGKGIQLCAYSPLGAK-------GTHWGSDAVMDAGVLQDIAASRGKSVAQ 388
           QQ +L EF + +GI + AYS  G +       G    +  + +   ++ IAA  GKS AQ
Sbjct: 195 QQPRLIEFAQSRGIAVTAYSSFGPQSFVELNQGRALNTSPLFENETIKAIAAKHGKSPAQ 254

Query: 387 VCLRWVYEQGDCLIVKSFDEARMRENLDVDGWELTEEERRRIAEIPQRKINL 232
           V LRW  ++G  +I KS    R+ EN DV+ ++L E++    A+I +  INL
Sbjct: 255 VLLRWSSQRGIAIIPKSNTVPRLLENKDVNSFDLDEQD---FADIAKLDINL 303



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>ALD2_CRIGR (O08782) Aldose reductase-related protein 2 (EC 1.1.1.21) (AR)|
           (Aldehyde reductase) (Aldo-keto reductase)
          Length = 315

 Score = 62.0 bits (149), Expect = 1e-09
 Identities = 34/97 (35%), Positives = 56/97 (57%), Gaps = 3/97 (3%)
 Frame = -1

Query: 543 QRKLREFCRGKGIQLCAYSPLGAKGTHWGSD---AVMDAGVLQDIAASRGKSVAQVCLRW 373
           Q KL E+C  KGI + AYSPLG+    W      ++++   +++IAA   K+ AQV +R+
Sbjct: 192 QEKLIEYCHSKGITVTAYSPLGSPNRPWAKPEDPSLLEDPKIKEIAAKHKKTSAQVLIRF 251

Query: 372 VYEQGDCLIVKSFDEARMRENLDVDGWELTEEERRRI 262
             ++   +I KS   AR+ EN  V  ++L+++E   I
Sbjct: 252 HIQRNVVVIPKSVTPARIHENFQVFDFQLSDQEMATI 288



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>AK1BA_HUMAN (O60218) Aldo-keto reductase family 1 member B10 (EC 1.1.1.-)|
           (Aldose reductase-like) (ARL-1) (Small intestine
           reductase) (SI reductase) (Aldose reductase-related
           protein) (ARP) (hARP)
          Length = 316

 Score = 61.6 bits (148), Expect = 1e-09
 Identities = 34/97 (35%), Positives = 57/97 (58%), Gaps = 3/97 (3%)
 Frame = -1

Query: 543 QRKLREFCRGKGIQLCAYSPLGAKGTHWGSD---AVMDAGVLQDIAASRGKSVAQVCLRW 373
           Q KL ++C  KGI + AYSPLG+    W      ++++   +++IAA   K+ AQV +R+
Sbjct: 193 QEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAKHKKTAAQVLIRF 252

Query: 372 VYEQGDCLIVKSFDEARMRENLDVDGWELTEEERRRI 262
             ++   +I KS   AR+ EN+ V  ++L++EE   I
Sbjct: 253 HIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATI 289



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>AK1C4_MACFU (Q95JH4) Aldo-keto reductase family 1 member C4 (EC 1.1.1.-)|
           (Chlordecone reductase) (EC 1.1.1.225) (CDR)
           (3-alpha-hydroxysteroid dehydrogenase type I) (EC
           1.1.1.50) (3-alpha-HSD1) (Dihydrodiol dehydrogenase 4)
           (DD4) (DD-4)
          Length = 323

 Score = 60.8 bits (146), Expect = 2e-09
 Identities = 38/124 (30%), Positives = 69/124 (55%), Gaps = 4/124 (3%)
 Frame = -1

Query: 543 QRKLREFCRGKGIQLCAYSPLGAKGTH-W---GSDAVMDAGVLQDIAASRGKSVAQVCLR 376
           Q KL +FC+ K I L A+S LG +    W    S A+++  VL  +A    +S A + LR
Sbjct: 199 QSKLLDFCKSKDIVLVAHSALGTQRHKLWVDQNSPALLEDPVLCALAKKHKRSPALIALR 258

Query: 375 WVYEQGDCLIVKSFDEARMRENLDVDGWELTEEERRRIAEIPQRKINLGKRYVSDHGPYK 196
           +  ++G  ++ KS++E R+REN+ V  ++LT E+ + + ++ +    +   ++ DH  Y 
Sbjct: 259 YQLQRGVVVLAKSYNEQRIRENVQVFEFQLTSEDMKVLDDLNRNFRYVVMDFLVDHPDYP 318

Query: 195 SLEE 184
             +E
Sbjct: 319 FSDE 322



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>AK1C4_MACFA (Q95JH5) Aldo-keto reductase family 1 member C4 (EC 1.1.1.-)|
           (Chlordecone reductase) (EC 1.1.1.225) (CDR)
           (3-alpha-hydroxysteroid dehydrogenase type I) (EC
           1.1.1.50) (3-alpha-HSD1) (Dihydrodiol dehydrogenase 4)
           (DD4) (DD-4)
          Length = 323

 Score = 60.8 bits (146), Expect = 2e-09
 Identities = 38/124 (30%), Positives = 69/124 (55%), Gaps = 4/124 (3%)
 Frame = -1

Query: 543 QRKLREFCRGKGIQLCAYSPLGAKGTH-W---GSDAVMDAGVLQDIAASRGKSVAQVCLR 376
           Q KL +FC+ K I L A+S LG +    W    S A+++  VL  +A    +S A + LR
Sbjct: 199 QSKLLDFCKSKDIVLVAHSALGTQRHKLWVDQNSPALLEDPVLCALAKKHKRSPALIALR 258

Query: 375 WVYEQGDCLIVKSFDEARMRENLDVDGWELTEEERRRIAEIPQRKINLGKRYVSDHGPYK 196
           +  ++G  ++ KS++E R+REN+ V  ++LT E+ + + ++ +    +   ++ DH  Y 
Sbjct: 259 YQLQRGVVVLAKSYNEQRIRENVQVFEFQLTSEDMKVLDDLNRNFRYVVMDFLVDHPDYP 318

Query: 195 SLEE 184
             +E
Sbjct: 319 FSDE 322



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>AK1C2_HUMAN (P52895) Aldo-keto reductase family 1 member C2 (EC 1.-.-.-)|
           (Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase) (EC
           1.3.1.20) (Type III 3-alpha-hydroxysteroid
           dehydrogenase) (EC 1.1.1.213) (3-alpha-HSD3)
           (Chlordecone reductase homolog HAKRD) (
          Length = 323

 Score = 60.8 bits (146), Expect = 2e-09
 Identities = 35/98 (35%), Positives = 59/98 (60%), Gaps = 4/98 (4%)
 Frame = -1

Query: 543 QRKLREFCRGKGIQLCAYSPLGA-KGTHW---GSDAVMDAGVLQDIAASRGKSVAQVCLR 376
           QRKL +FC+ K I L AYS LG+ +   W    S  +++  VL  +A    ++ A + LR
Sbjct: 199 QRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALR 258

Query: 375 WVYEQGDCLIVKSFDEARMRENLDVDGWELTEEERRRI 262
           +  ++G  ++ KS++E R+R+N+ V  ++LT EE + I
Sbjct: 259 YQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAI 296



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>AK1C1_MACFU (Q95JH6) Aldo-keto reductase family 1 member C1 homolog (EC|
           1.-.-.-) (20-alpha-hydroxysteroid dehydrogenase) (EC
           1.1.1.149) (20-alpha-HSD) (Dihydrodiol dehydrogenase 1)
           (DD-1) (DD1)
          Length = 323

 Score = 60.8 bits (146), Expect = 2e-09
 Identities = 35/98 (35%), Positives = 59/98 (60%), Gaps = 4/98 (4%)
 Frame = -1

Query: 543 QRKLREFCRGKGIQLCAYSPLGA-KGTHW---GSDAVMDAGVLQDIAASRGKSVAQVCLR 376
           QRKL +FC+ K I L AYS LG+ +   W    S  +++  VL  +A    ++ A + LR
Sbjct: 199 QRKLLDFCKSKDIVLVAYSALGSHREKPWVDQNSPVLLEDPVLCALAKKHKRTPALIALR 258

Query: 375 WVYEQGDCLIVKSFDEARMRENLDVDGWELTEEERRRI 262
           +  ++G  ++ KS++E R+REN+ V  ++LT E+ + I
Sbjct: 259 YQLQRGVVVLAKSYNEQRIRENMKVFEFQLTSEDMKAI 296



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>AK1C1_HUMAN (Q04828) Aldo-keto reductase family 1 member C1 (EC 1.1.1.-)|
           (20-alpha-hydroxysteroid dehydrogenase) (EC 1.1.1.149)
           (20-alpha-HSD) (Trans-1,2-dihydrobenzene-1,2-diol
           dehydrogenase) (EC 1.3.1.20) (High-affinity hepatic bile
           acid-binding protei
          Length = 323

 Score = 60.8 bits (146), Expect = 2e-09
 Identities = 35/98 (35%), Positives = 59/98 (60%), Gaps = 4/98 (4%)
 Frame = -1

Query: 543 QRKLREFCRGKGIQLCAYSPLGA-KGTHW---GSDAVMDAGVLQDIAASRGKSVAQVCLR 376
           QRKL +FC+ K I L AYS LG+ +   W    S  +++  VL  +A    ++ A + LR
Sbjct: 199 QRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALR 258

Query: 375 WVYEQGDCLIVKSFDEARMRENLDVDGWELTEEERRRI 262
           +  ++G  ++ KS++E R+R+N+ V  ++LT EE + I
Sbjct: 259 YQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAI 296



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>AK1C1_PONPY (Q5REQ0) Aldo-keto reductase family 1 member C1 homolog (EC|
           1.-.-.-) (20-alpha-hydroxysteroid dehydrogenase) (EC
           1.1.1.149) (20-alpha-HSD)
          Length = 323

 Score = 60.5 bits (145), Expect = 3e-09
 Identities = 34/98 (34%), Positives = 58/98 (59%), Gaps = 4/98 (4%)
 Frame = -1

Query: 543 QRKLREFCRGKGIQLCAYSPLGA----KGTHWGSDAVMDAGVLQDIAASRGKSVAQVCLR 376
           QRKL +FC+ K I L AYS LG+    K     S  +++  VL  +A    ++ A + LR
Sbjct: 199 QRKLLDFCKSKDIVLVAYSALGSHREEKWVDPNSPVLLEDPVLCALAKKHKQTPALIALR 258

Query: 375 WVYEQGDCLIVKSFDEARMRENLDVDGWELTEEERRRI 262
           +  ++G  ++ KS++E R+R+N+ V  ++LT E+ + I
Sbjct: 259 YQLQRGVVVLAKSYNEQRIRQNMQVFDFQLTSEDMKTI 296



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>XYL1_ASPNG (Q9P8R5) NAD(P)H-dependent D-xylose reductase (EC 1.1.1.-) (XR)|
          Length = 319

 Score = 60.5 bits (145), Expect = 3e-09
 Identities = 34/102 (33%), Positives = 56/102 (54%), Gaps = 7/102 (6%)
 Frame = -1

Query: 543 QRKLREFCRGKGIQLCAYSPLGAKG-------THWGSDAVMDAGVLQDIAASRGKSVAQV 385
           Q +L E+ + +G+ + AYS  G              S  + +  +++ IA   G++ AQV
Sbjct: 197 QTRLVEYAQKEGLTVTAYSSFGPLSFLELSVQNAVDSPPLFEHQLVKSIAEKHGRTPAQV 256

Query: 384 CLRWVYEQGDCLIVKSFDEARMRENLDVDGWELTEEERRRIA 259
            LRW  ++G  +I KS +  R+++NLDV GW L EEE + I+
Sbjct: 257 LLRWATQRGIAVIPKSNNPQRLKQNLDVTGWNLEEEEIKAIS 298



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>ALDR_RAT (P07943) Aldose reductase (EC 1.1.1.21) (AR) (Aldehyde reductase)|
          Length = 315

 Score = 59.7 bits (143), Expect = 5e-09
 Identities = 34/93 (36%), Positives = 54/93 (58%), Gaps = 3/93 (3%)
 Frame = -1

Query: 543 QRKLREFCRGKGIQLCAYSPLGAKGTHWGSD---AVMDAGVLQDIAASRGKSVAQVCLRW 373
           Q KL E+C  KGI + AYSPLG+    W      ++++   +++IAA   K+ AQV +R+
Sbjct: 192 QEKLIEYCHCKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKEIAAKYNKTTAQVLIRF 251

Query: 372 VYEQGDCLIVKSFDEARMRENLDVDGWELTEEE 274
             ++   +I KS   AR+ EN  V  +EL+ E+
Sbjct: 252 PIQRNLVVIPKSVTPARIAENFKVFDFELSNED 284



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>AK1C3_PONPY (Q5R7C9) Aldo-keto reductase family 1 member C3 homolog (EC|
           1.-.-.-) (Trans-1,2-dihydrobenzene-1,2-diol
           dehydrogenase) (EC 1.3.1.20) (3-alpha-hydroxysteroid
           dehydrogenase type 2) (EC 1.1.1.213) (3-alpha-HSD type
           2) (Prostaglandin F synthase)
          Length = 323

 Score = 59.3 bits (142), Expect = 7e-09
 Identities = 37/122 (30%), Positives = 65/122 (53%), Gaps = 4/122 (3%)
 Frame = -1

Query: 537 KLREFCRGKGIQLCAYSPLGA-KGTHW---GSDAVMDAGVLQDIAASRGKSVAQVCLRWV 370
           KL +FC+ K I L AYS LG+ +   W    S  +++  VL  +A    ++ A + LR+ 
Sbjct: 201 KLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQ 260

Query: 369 YEQGDCLIVKSFDEARMRENLDVDGWELTEEERRRIAEIPQRKINLGKRYVSDHGPYKSL 190
            ++G  ++ KS++E R+REN+ V  ++LT E+ R I  + +         ++ H  Y   
Sbjct: 261 LQRGVVVLAKSYNEQRIRENVQVFEFQLTAEDMRAIDGLNRNLHYFNSDSLASHPNYPYS 320

Query: 189 EE 184
           +E
Sbjct: 321 DE 322



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>AK1C1_MACFA (Q95JH7) Aldo-keto reductase family 1 member C1 homolog (EC|
           1.-.-.-) (20-alpha-hydroxysteroid dehydrogenase) (EC
           1.1.1.149) (20-alpha-HSD) (Dihydrodiol dehydrogenase 1)
           (DD-1) (DD1)
          Length = 323

 Score = 59.3 bits (142), Expect = 7e-09
 Identities = 34/98 (34%), Positives = 59/98 (60%), Gaps = 4/98 (4%)
 Frame = -1

Query: 543 QRKLREFCRGKGIQLCAYSPLGA-KGTHW---GSDAVMDAGVLQDIAASRGKSVAQVCLR 376
           QRKL +FC+ K I L A+S LG+ +   W    S  +++  VL  +A    ++ A + LR
Sbjct: 199 QRKLLDFCKSKDIVLVAFSALGSHREKPWVDQNSPVLLEDPVLCALAKKHKRTPALIALR 258

Query: 375 WVYEQGDCLIVKSFDEARMRENLDVDGWELTEEERRRI 262
           +  ++G  ++ KS++E R+REN+ V  ++LT E+ + I
Sbjct: 259 YQLQRGVVVLAKSYNEQRIRENMKVFEFQLTSEDMKAI 296



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>ALDR_PIG (P80276) Aldose reductase (EC 1.1.1.21) (AR) (Aldehyde reductase)|
          Length = 315

 Score = 58.9 bits (141), Expect = 9e-09
 Identities = 36/95 (37%), Positives = 52/95 (54%), Gaps = 5/95 (5%)
 Frame = -1

Query: 543 QRKLREFCRGKGIQLCAYSPLGAKGTHWGSDAVMDAGVLQD-----IAASRGKSVAQVCL 379
           Q KL E+C+ KGI + AYSPLG+    W      D  +L+D     IAA   K+ AQV +
Sbjct: 192 QEKLIEYCKSKGIVVTAYSPLGSPDRPWAKPE--DPSLLEDPRIKAIAAKYNKTTAQVLI 249

Query: 378 RWVYEQGDCLIVKSFDEARMRENLDVDGWELTEEE 274
           R+  ++   +I KS    R+ EN  V  +EL+ E+
Sbjct: 250 RFPMQRNLIVIPKSVTPERIAENFQVFDFELSPED 284



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>ALDR_MOUSE (P45376) Aldose reductase (EC 1.1.1.21) (AR) (Aldehyde reductase)|
          Length = 315

 Score = 58.9 bits (141), Expect = 9e-09
 Identities = 36/95 (37%), Positives = 52/95 (54%), Gaps = 5/95 (5%)
 Frame = -1

Query: 543 QRKLREFCRGKGIQLCAYSPLGAKGTHWGSDAVMDAGVLQD-----IAASRGKSVAQVCL 379
           Q KL E+C  KGI + AYSPLG+    W      D  +L+D     IAA   K+ AQV +
Sbjct: 192 QEKLIEYCHSKGIVVTAYSPLGSPDRPWAKPE--DPSLLEDPRIKAIAAKYNKTTAQVLI 249

Query: 378 RWVYEQGDCLIVKSFDEARMRENLDVDGWELTEEE 274
           R+  ++   +I KS    R+ ENL V  +E++ E+
Sbjct: 250 RFPIQRNLVVIPKSVTPVRIAENLKVFDFEVSSED 284



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>AK1D1_MOUSE (Q8VCX1) 3-oxo-5-beta-steroid 4-dehydrogenase (EC 1.3.99.6)|
           (Delta(4)-3-ketosteroid 5-beta-reductase) (Aldo-keto
           reductase family 1 member D1)
          Length = 325

 Score = 58.2 bits (139), Expect = 2e-08
 Identities = 42/129 (32%), Positives = 65/129 (50%), Gaps = 9/129 (6%)
 Frame = -1

Query: 543 QRKLREFCRGKGIQLCAYSPLGA-KGTHW---GSDAVMDAGVLQDIAASRGKSVAQVCLR 376
           Q KL +FC+   I + A+SPLG  +   W    S  +++  +L  +     K+ AQ+ LR
Sbjct: 201 QTKLLKFCQQHDIVIVAHSPLGTCRNPSWVNVSSPPLLNDELLTSLGKKYNKTQAQIVLR 260

Query: 375 WVYEQGDCLIVKSFDEARMRENLDVDGWELTEEERRRIAEIPQRKINLGKRYV-----SD 211
           +  ++G  +I KSF   R++EN  +  + LTEEE + I       +N   RYV     SD
Sbjct: 261 FNIQRGIVVIPKSFTPERIKENFQIFDFSLTEEEMKDI-----DALNKNVRYVELLMWSD 315

Query: 210 HGPYKSLEE 184
           H  Y   +E
Sbjct: 316 HPEYPFHDE 324



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>AK1C4_HUMAN (P17516) Aldo-keto reductase family 1 member C4 (EC 1.1.1.-)|
           (Chlordecone reductase) (EC 1.1.1.225) (CDR)
           (3-alpha-hydroxysteroid dehydrogenase type I) (EC
           1.1.1.50) (3-alpha-HSD1) (Dihydrodiol dehydrogenase 4)
           (DD4) (HAKRA)
          Length = 323

 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 36/124 (29%), Positives = 67/124 (54%), Gaps = 4/124 (3%)
 Frame = -1

Query: 543 QRKLREFCRGKGIQLCAYSPLGAKGTH-W---GSDAVMDAGVLQDIAASRGKSVAQVCLR 376
           Q KL +FC+ K I L A+S LG +    W    S  +++  VL  +A    ++ A + LR
Sbjct: 199 QSKLLDFCKSKDIVLVAHSALGTQRHKLWVDPNSPVLLEDPVLCALAKKHKRTPALIALR 258

Query: 375 WVYEQGDCLIVKSFDEARMRENLDVDGWELTEEERRRIAEIPQRKINLGKRYVSDHGPYK 196
           +  ++G  ++ KS++E R+REN+ V  ++LT E+ + +  + +    +   ++ DH  Y 
Sbjct: 259 YQLQRGVVVLAKSYNEQRIRENIQVFEFQLTSEDMKVLDGLNRNYRYVVMDFLMDHPDYP 318

Query: 195 SLEE 184
             +E
Sbjct: 319 FSDE 322



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>AK1D1_HUMAN (P51857) 3-oxo-5-beta-steroid 4-dehydrogenase (EC 1.3.1.3)|
           (Delta(4)-3-ketosteroid 5-beta-reductase) (Aldo-keto
           reductase family 1 member D1)
          Length = 326

 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 41/129 (31%), Positives = 65/129 (50%), Gaps = 9/129 (6%)
 Frame = -1

Query: 543 QRKLREFCRGKGIQLCAYSPLG-AKGTHW---GSDAVMDAGVLQDIAASRGKSVAQVCLR 376
           Q KL +FC+   I + AYSPLG ++   W    S  ++   +L  +     K+ AQ+ LR
Sbjct: 202 QPKLLKFCQQHDIVITAYSPLGTSRNPIWVNVSSPPLLKDALLNSLGKRYNKTAAQIVLR 261

Query: 375 WVYEQGDCLIVKSFDEARMRENLDVDGWELTEEERRRIAEIPQRKINLGKRYVS-----D 211
           +  ++G  +I KSF+  R++EN  +  + LTEEE + I       +N   R+V      D
Sbjct: 262 FNIQRGVVVIPKSFNLERIKENFQIFDFSLTEEEMKDI-----EALNKNVRFVELLMWRD 316

Query: 210 HGPYKSLEE 184
           H  Y   +E
Sbjct: 317 HPEYPFHDE 325



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>DKGA_ECOLI (Q46857) 2,5-diketo-D-gluconic acid reductase A (EC 1.1.1.274)|
           (2,5-DKG reductase A) (2,5-DKGR A) (25DKGR-A) (AKR5C)
          Length = 275

 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 36/102 (35%), Positives = 55/102 (53%)
 Frame = -1

Query: 546 QQRKLREFCRGKGIQLCAYSPLGAKGTHWGSDAVMDAGVLQDIAASRGKSVAQVCLRWVY 367
           QQR+L  +     IQ  ++SPL       G   V D  V++D+A   GK+ AQ+ +RW  
Sbjct: 168 QQRQLHAWNATHKIQTESWSPLAQ-----GGKGVFDQKVIRDLADKYGKTPAQIVIRWHL 222

Query: 366 EQGDCLIVKSFDEARMRENLDVDGWELTEEERRRIAEIPQRK 241
           + G  +I KS   +R+ EN DV  + L ++E   IA++ Q K
Sbjct: 223 DSGLVVIPKSVTPSRIAENFDVWDFRLDKDELGEIAKLDQGK 264



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>DKGA_ECO57 (Q8XBT6) 2,5-diketo-D-gluconic acid reductase A (EC 1.1.1.274)|
           (2,5-DKG reductase A) (2,5-DKGR A) (25DKGR-A) (AKR5C)
          Length = 275

 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 36/102 (35%), Positives = 55/102 (53%)
 Frame = -1

Query: 546 QQRKLREFCRGKGIQLCAYSPLGAKGTHWGSDAVMDAGVLQDIAASRGKSVAQVCLRWVY 367
           QQR+L  +     IQ  ++SPL       G   V D  V++D+A   GK+ AQ+ +RW  
Sbjct: 168 QQRQLHAWNATHKIQTESWSPLAQ-----GGKGVFDQKVIRDLADKYGKTPAQIVIRWHL 222

Query: 366 EQGDCLIVKSFDEARMRENLDVDGWELTEEERRRIAEIPQRK 241
           + G  +I KS   +R+ EN DV  + L ++E   IA++ Q K
Sbjct: 223 DSGLVVIPKSVTPSRIAENFDVWDFRLDKDELGEIAKLDQGK 264



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>PGFS2_BOVIN (P52897) Prostaglandin-F synthase 2 (EC 1.1.1.188) (PGF synthase 2)|
           (PGF 2) (Prostaglandin-D2 11 reductase 2) (PGFSII)
          Length = 323

 Score = 57.4 bits (137), Expect = 3e-08
 Identities = 35/98 (35%), Positives = 58/98 (59%), Gaps = 4/98 (4%)
 Frame = -1

Query: 543 QRKLREFCRGKGIQLCAYSPLGAKG-THW---GSDAVMDAGVLQDIAASRGKSVAQVCLR 376
           Q KL EFC+   I L AY+ LGA+  + W    +  +++  VL  IA    ++ A V LR
Sbjct: 199 QSKLLEFCKSHDIVLVAYAALGAQLLSEWVNSNNPVLLEDPVLCAIAKKHKQTPALVALR 258

Query: 375 WVYEQGDCLIVKSFDEARMRENLDVDGWELTEEERRRI 262
           +  ++G  ++ KSF++ R++EN+ V  +ELT E+ + I
Sbjct: 259 YQVQRGVVVLAKSFNKKRIKENMQVFDFELTPEDMKAI 296



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>PGFS1_BOVIN (P05980) Prostaglandin-F synthase 1 (EC 1.1.1.188) (PGF synthase 1)|
           (PGF 1) (Prostaglandin-D2 11 reductase 1) (PGFSI)
          Length = 323

 Score = 57.4 bits (137), Expect = 3e-08
 Identities = 35/98 (35%), Positives = 58/98 (59%), Gaps = 4/98 (4%)
 Frame = -1

Query: 543 QRKLREFCRGKGIQLCAYSPLGAKG-THW---GSDAVMDAGVLQDIAASRGKSVAQVCLR 376
           Q KL EFC+   I L AY+ LGA+  + W    +  +++  VL  IA    ++ A V LR
Sbjct: 199 QSKLLEFCKSHDIVLVAYAALGAQLLSEWVNSNNPVLLEDPVLCAIAKKHKQTPALVALR 258

Query: 375 WVYEQGDCLIVKSFDEARMRENLDVDGWELTEEERRRI 262
           +  ++G  ++ KSF++ R++EN+ V  +ELT E+ + I
Sbjct: 259 YQVQRGVVVLAKSFNKKRIKENMQVFDFELTPEDMKAI 296



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>PE2R_RABIT (P80508) Prostaglandin-E(2) 9-reductase (EC 1.1.1.189)|
           (20-alpha-hydroxysteroid dehydrogenase) (EC 1.1.1.149)
           (20-alpha-HSD)
          Length = 323

 Score = 57.0 bits (136), Expect = 3e-08
 Identities = 36/114 (31%), Positives = 63/114 (55%), Gaps = 4/114 (3%)
 Frame = -1

Query: 543 QRKLREFCRGKGIQLCAYSPLGA-KGTHW---GSDAVMDAGVLQDIAASRGKSVAQVCLR 376
           Q KL EFC+ KGI L AYS LG+ +   W    +  +++  ++  +A    ++ A + LR
Sbjct: 199 QGKLLEFCKSKGIVLVAYSALGSHREPEWVDQSAPVLLEDPLIGALAKKHQQTPALIALR 258

Query: 375 WVYEQGDCLIVKSFDEARMRENLDVDGWELTEEERRRIAEIPQRKINLGKRYVS 214
           +  ++G  ++ KSF E R++EN+ V  ++L  E+ + I       +N   RYV+
Sbjct: 259 YQLQRGIVVLAKSFTEKRIKENIQVFEFQLPSEDMKVI-----DSLNRNFRYVT 307



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>ALDR_RABIT (P15122) Aldose reductase (EC 1.1.1.21) (AR) (Aldehyde reductase)|
          Length = 315

 Score = 57.0 bits (136), Expect = 3e-08
 Identities = 35/95 (36%), Positives = 51/95 (53%), Gaps = 5/95 (5%)
 Frame = -1

Query: 543 QRKLREFCRGKGIQLCAYSPLGAKGTHWGSDAVMDAGVLQD-----IAASRGKSVAQVCL 379
           Q KL ++C  KGI + AYSPLG+    W      D  +L+D     IA    K+ AQV +
Sbjct: 192 QEKLIQYCHSKGIVVTAYSPLGSPDRPWAKPE--DPSLLEDPRIKAIADKHKKTTAQVLI 249

Query: 378 RWVYEQGDCLIVKSFDEARMRENLDVDGWELTEEE 274
           R+  ++   +I KS   AR+ EN  V  +EL+ E+
Sbjct: 250 RFPMQRNLVVIPKSVTPARIAENFQVFDFELSSED 284



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>ALDR_HUMAN (P15121) Aldose reductase (EC 1.1.1.21) (AR) (Aldehyde reductase)|
          Length = 315

 Score = 57.0 bits (136), Expect = 3e-08
 Identities = 34/95 (35%), Positives = 52/95 (54%), Gaps = 5/95 (5%)
 Frame = -1

Query: 543 QRKLREFCRGKGIQLCAYSPLGAKGTHWGSDAVMDAGVLQD-----IAASRGKSVAQVCL 379
           Q KL ++C+ KGI + AYSPLG+    W      D  +L+D     IAA   K+ AQV +
Sbjct: 192 QEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPE--DPSLLEDPRIKAIAAKHNKTTAQVLI 249

Query: 378 RWVYEQGDCLIVKSFDEARMRENLDVDGWELTEEE 274
           R+  ++   +I KS    R+ EN  V  +EL+ ++
Sbjct: 250 RFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQD 284



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>AK1D1_RABIT (Q9TV64) 3-oxo-5-beta-steroid 4-dehydrogenase (EC 1.3.99.6)|
           (Delta(4)-3-ketosteroid 5-beta-reductase) (Aldo-keto
           reductase family 1 member D1)
          Length = 326

 Score = 57.0 bits (136), Expect = 3e-08
 Identities = 41/129 (31%), Positives = 65/129 (50%), Gaps = 9/129 (6%)
 Frame = -1

Query: 543 QRKLREFCRGKGIQLCAYSPLGA-KGTHWGSDAV---MDAGVLQDIAASRGKSVAQVCLR 376
           Q KL +FC+   I + AYSPLG  +   W + ++   +   +L  +     K+ AQ+ LR
Sbjct: 202 QPKLLKFCQQHDIIIVAYSPLGTCRNPMWVNTSLPPLLKDTLLNSLGKKYKKTAAQIVLR 261

Query: 375 WVYEQGDCLIVKSFDEARMRENLDVDGWELTEEERRRIAEIPQRKINLGKRYVS-----D 211
           +  ++G  +I KSF+  R++EN  +  + LTEEE + I       +N   RYV      D
Sbjct: 262 FNVQRGVVVIPKSFNPERIKENFQIFDFSLTEEEMKDI-----EALNKNVRYVELLMWRD 316

Query: 210 HGPYKSLEE 184
           H  Y   +E
Sbjct: 317 HPEYPFNDE 325



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>AK1C3_HUMAN (P42330) Aldo-keto reductase family 1 member C3 (EC 1.-.-.-)|
           (Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase) (EC
           1.3.1.20) (3-alpha-hydroxysteroid dehydrogenase type 2)
           (EC 1.1.1.213) (3-alpha-HSD type 2) (3-alpha-HSD type
           II, brain) (Prost
          Length = 323

 Score = 56.6 bits (135), Expect = 4e-08
 Identities = 32/96 (33%), Positives = 57/96 (59%), Gaps = 4/96 (4%)
 Frame = -1

Query: 537 KLREFCRGKGIQLCAYSPLGA-KGTHW---GSDAVMDAGVLQDIAASRGKSVAQVCLRWV 370
           KL +FC+ K I L AYS LG+ +   W    S  +++  VL  +A    ++ A + LR+ 
Sbjct: 201 KLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQ 260

Query: 369 YEQGDCLIVKSFDEARMRENLDVDGWELTEEERRRI 262
            ++G  ++ KS++E R+R+N+ V  ++LT E+ + I
Sbjct: 261 LQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDMKAI 296



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>ALD2_MOUSE (P45377) Aldose reductase-related protein 2 (EC 1.1.1.21) (AR)|
           (Aldehyde reductase) (Fibroblast growth factor-regulated
           protein) (FR-1 protein)
          Length = 315

 Score = 56.6 bits (135), Expect = 4e-08
 Identities = 32/97 (32%), Positives = 57/97 (58%), Gaps = 3/97 (3%)
 Frame = -1

Query: 543 QRKLREFCRGKGIQLCAYSPLGAKGTHWGSD---AVMDAGVLQDIAASRGKSVAQVCLRW 373
           Q KL ++C  KGI + AYSPLG+           ++++   +++IAA   K+ AQV +R+
Sbjct: 192 QEKLIQYCHSKGISVTAYSPLGSPDRPSAKPEDPSLLEDPKIKEIAAKHEKTSAQVLIRF 251

Query: 372 VYEQGDCLIVKSFDEARMRENLDVDGWELTEEERRRI 262
             ++   +I KS   +R++EN+ V  ++L++EE   I
Sbjct: 252 HIQRNVVVIPKSVTPSRIQENIQVFDFQLSDEEMATI 288



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>ALDR_BOVIN (P16116) Aldose reductase (EC 1.1.1.21) (AR) (Aldehyde reductase)|
           (20-alpha-hydroxysteroid dehydrogenase) (EC 1.1.1.149)
           (20-alpha-HSD)
          Length = 315

 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 34/95 (35%), Positives = 50/95 (52%), Gaps = 5/95 (5%)
 Frame = -1

Query: 543 QRKLREFCRGKGIQLCAYSPLGAKGTHWGSDAVMDAGVLQD-----IAASRGKSVAQVCL 379
           Q KL ++C  KGI + AYSPLG+    W      D  +L+D     IA    K+ AQV +
Sbjct: 192 QEKLIQYCNSKGIVVTAYSPLGSPDRPWAKPE--DPSILEDPRIKAIADKYNKTTAQVLI 249

Query: 378 RWVYEQGDCLIVKSFDEARMRENLDVDGWELTEEE 274
           R+  ++   +I KS    R+ EN  V  +EL +E+
Sbjct: 250 RFPIQRNLIVIPKSVTPERIAENFQVFDFELDKED 284



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>AK1A1_MOUSE (Q9JII6) Alcohol dehydrogenase [NADP+] (EC 1.1.1.2) (Aldehyde|
           reductase) (Aldo-keto reductase family 1 member A1)
          Length = 324

 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 28/97 (28%), Positives = 53/97 (54%), Gaps = 3/97 (3%)
 Frame = -1

Query: 543 QRKLREFCRGKGIQLCAYSPLGAKGTHW---GSDAVMDAGVLQDIAASRGKSVAQVCLRW 373
           Q +L   C  +G+++ AYSPLG+    W       +++  V+  +A   G+S AQ+ LRW
Sbjct: 192 QNELIAHCHARGLEVTAYSPLGSSDRAWRHPDEPVLLEEPVVLALAEKHGRSPAQILLRW 251

Query: 372 VYEQGDCLIVKSFDEARMRENLDVDGWELTEEERRRI 262
             ++    I KS + +R+ +N+ V  +  + EE +++
Sbjct: 252 QVQRKVICIPKSINPSRILQNIQVFDFTFSPEEMKQL 288



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>AK1A1_RAT (P51635) Alcohol dehydrogenase [NADP+] (EC 1.1.1.2) (Aldehyde|
           reductase) (Aldo-keto reductase family 1 member A1)
           (3-DG-reducing enzyme)
          Length = 324

 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 28/97 (28%), Positives = 53/97 (54%), Gaps = 3/97 (3%)
 Frame = -1

Query: 543 QRKLREFCRGKGIQLCAYSPLGAKGTHW---GSDAVMDAGVLQDIAASRGKSVAQVCLRW 373
           Q +L   C+ +G+++ AYSPLG+    W       +++  V+  +A   G+S AQ+ LRW
Sbjct: 192 QNELIAHCQARGLEVTAYSPLGSSDRAWRHPDEPVLLEEPVVLALAEKHGRSPAQILLRW 251

Query: 372 VYEQGDCLIVKSFDEARMRENLDVDGWELTEEERRRI 262
             ++    I KS   +R+ +N+ V  +  + EE +++
Sbjct: 252 QVQRKVICIPKSITPSRILQNIQVFDFTFSPEEMKQL 288



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>AK1A1_PIG (P50578) Alcohol dehydrogenase [NADP+] (EC 1.1.1.2) (Aldehyde|
           reductase) (Aldo-keto reductase family 1 member A1)
          Length = 324

 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 28/97 (28%), Positives = 53/97 (54%), Gaps = 3/97 (3%)
 Frame = -1

Query: 543 QRKLREFCRGKGIQLCAYSPLGAKGTHW---GSDAVMDAGVLQDIAASRGKSVAQVCLRW 373
           Q +L   C+ +G+++ AYSPLG+    W       +++  V+Q +A    +S AQ+ LRW
Sbjct: 192 QNELIAHCQARGLEVTAYSPLGSSDRAWRDPNEPVLLEEPVVQALAEKYNRSPAQILLRW 251

Query: 372 VYEQGDCLIVKSFDEARMRENLDVDGWELTEEERRRI 262
             ++    I KS   +R+ +N+ V  +  + EE +++
Sbjct: 252 QVQRKVICIPKSVTPSRIPQNIQVFDFTFSPEEMKQL 288



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>XYL1_PACTA (P78736) NAD(P)H-dependent D-xylose reductase (EC 1.1.1.-) (XR)|
          Length = 318

 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 36/105 (34%), Positives = 54/105 (51%), Gaps = 7/105 (6%)
 Frame = -1

Query: 546 QQRKLREFCRGKGIQLCAYSPLG-------AKGTHWGSDAVMDAGVLQDIAASRGKSVAQ 388
           QQ KL E+ + KGI +  YS  G          T   +  + +   +  IAA  GK+  Q
Sbjct: 195 QQNKLVEYAQLKGIVVTGYSNFGPLSFLELGNETAKKTQPLYENKTITTIAAKHGKTPFQ 254

Query: 387 VCLRWVYEQGDCLIVKSFDEARMRENLDVDGWELTEEERRRIAEI 253
           V LRWV ++G  +I KS     +  NL VD ++LT+E+   IA++
Sbjct: 255 VLLRWVNQRGIAIIPKSTFPNTLAVNLHVDEFDLTKEDFEEIAKL 299



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>AK1A1_HUMAN (P14550) Alcohol dehydrogenase [NADP+] (EC 1.1.1.2) (Aldehyde|
           reductase) (Aldo-keto reductase family 1 member A1)
          Length = 324

 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 31/112 (27%), Positives = 58/112 (51%), Gaps = 3/112 (2%)
 Frame = -1

Query: 543 QRKLREFCRGKGIQLCAYSPLGAKGTHW---GSDAVMDAGVLQDIAASRGKSVAQVCLRW 373
           Q +L   C+ +G+++ AYSPLG+    W       +++  V+  +A   G+S AQ+ LRW
Sbjct: 192 QNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLLEEPVVLALAEKYGRSPAQILLRW 251

Query: 372 VYEQGDCLIVKSFDEARMRENLDVDGWELTEEERRRIAEIPQRKINLGKRYV 217
             ++    I KS   +R+ +N+ V  +  + EE +++       +N   RY+
Sbjct: 252 QVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQL-----NALNKNWRYI 298



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>AK1CD_MESAU (P82809) Aldo-keto reductase family 1 member C13 (EC 1.1.1.-)|
           (Morphine 6-dehydrogenase) (EC 1.1.1.218)
          Length = 322

 Score = 53.9 bits (128), Expect = 3e-07
 Identities = 36/124 (29%), Positives = 65/124 (52%), Gaps = 4/124 (3%)
 Frame = -1

Query: 543 QRKLREFCRGKGIQLCAYSPLGAKG-THW---GSDAVMDAGVLQDIAASRGKSVAQVCLR 376
           Q KL ++C+ K I L A+  LG +    W    S  +++  VL   A    +S A + LR
Sbjct: 199 QSKLLDYCKSKDIVLVAFGALGTQRYKEWVDQDSPVLLNDPVLCGGAKXXXRSPALIALR 258

Query: 375 WVYEQGDCLIVKSFDEARMRENLDVDGWELTEEERRRIAEIPQRKINLGKRYVSDHGPYK 196
           ++ ++G   + +SF E+ M+ENL V  ++L+ E+ + +  + +    L  ++ +DH  Y 
Sbjct: 259 YLVQRGVVPLAQSFYESEMKENLQVFEFQLSPEDMKILDGLNKNFRYLPAQFFADHPEYP 318

Query: 195 SLEE 184
             EE
Sbjct: 319 FSEE 322



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>XYL2_CANTR (P87039) NADPH-dependent D-xylose reductase II,III (EC 1.1.1.-)|
           (XR)
          Length = 324

 Score = 53.1 bits (126), Expect = 5e-07
 Identities = 35/116 (30%), Positives = 59/116 (50%), Gaps = 7/116 (6%)
 Frame = -1

Query: 546 QQRKLREFCRGKGIQLCAYSPLGAKG-------THWGSDAVMDAGVLQDIAASRGKSVAQ 388
           QQ KL E+ +  GI +  YS  G +            +  + +   ++ IA   GKS AQ
Sbjct: 201 QQPKLIEYVQKAGIAITGYSSFGPQSFLELESKRALNTPTLFEHETIKSIADKHGKSPAQ 260

Query: 387 VCLRWVYEQGDCLIVKSFDEARMRENLDVDGWELTEEERRRIAEIPQRKINLGKRY 220
           V LRW  ++   +I KS +  R+ +NL V  ++LT+++   IA     K+++G R+
Sbjct: 261 VLLRWATQRNIAVIPKSNNPERLAQNLSVVDFDLTKDDLDNIA-----KLDIGLRF 311



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>DKGA_SALTY (Q8ZM06) 2,5-diketo-D-gluconic acid reductase A (EC 1.1.1.274)|
           (2,5-DKG reductase A) (2,5-DKGR A) (25DKGR-A) (AKR5C)
          Length = 275

 Score = 53.1 bits (126), Expect = 5e-07
 Identities = 34/102 (33%), Positives = 55/102 (53%)
 Frame = -1

Query: 546 QQRKLREFCRGKGIQLCAYSPLGAKGTHWGSDAVMDAGVLQDIAASRGKSVAQVCLRWVY 367
           QQR+L  +     IQ  ++SPL       G + V D  V++++A   GK+ AQ+ +RW  
Sbjct: 168 QQRQLHAWNATHKIQTESWSPLAQ-----GGEGVFDQKVIRELADKYGKTPAQIVIRWHL 222

Query: 366 EQGDCLIVKSFDEARMRENLDVDGWELTEEERRRIAEIPQRK 241
           + G  +I KS   +R+ EN  V  + L ++E   IA++ Q K
Sbjct: 223 DCGLVVIPKSVTPSRIAENFAVWDFRLDKDELGEIAKLDQGK 264



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>DDBX_BOVIN (P52898) Dihydrodiol dehydrogenase 3 (EC 1.-.-.-) (Prostaglandin F|
           synthase)
          Length = 323

 Score = 52.8 bits (125), Expect = 6e-07
 Identities = 32/98 (32%), Positives = 56/98 (57%), Gaps = 4/98 (4%)
 Frame = -1

Query: 543 QRKLREFCRGKGIQLCAYSPLGAKGT-HWGSDAV---MDAGVLQDIAASRGKSVAQVCLR 376
           Q KL +FC+   I L AY  LG++    W +  +   ++  VL  IA    ++ A V LR
Sbjct: 199 QSKLLDFCKSHDIVLVAYGALGSQRLKEWVNPNLPFLLEDPVLSAIAKKHRQTPALVALR 258

Query: 375 WVYEQGDCLIVKSFDEARMRENLDVDGWELTEEERRRI 262
           +  ++G  ++ KS+++ R++EN+ V  +ELT E+ + I
Sbjct: 259 YQIQRGVVVLAKSYNKKRIKENIQVFDFELTPEDMKAI 296



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>DKGA_SALTI (P58744) 2,5-diketo-D-gluconic acid reductase A (EC 1.1.1.274)|
           (2,5-DKG reductase A) (2,5-DKGR A) (25DKGR-A) (AKR5C)
          Length = 275

 Score = 52.4 bits (124), Expect = 8e-07
 Identities = 34/102 (33%), Positives = 54/102 (52%)
 Frame = -1

Query: 546 QQRKLREFCRGKGIQLCAYSPLGAKGTHWGSDAVMDAGVLQDIAASRGKSVAQVCLRWVY 367
           QQR+L        IQ  ++SPL       G + V D  V++++A   GK+ AQ+ +RW  
Sbjct: 168 QQRQLHAXNATHKIQTESWSPLAQ-----GGEGVFDQKVIRELADKYGKTPAQIVIRWHL 222

Query: 366 EQGDCLIVKSFDEARMRENLDVDGWELTEEERRRIAEIPQRK 241
           + G  +I KS   +R+ EN  V  + L ++E   IA++ Q K
Sbjct: 223 DCGLVVIPKSVTPSRIAENFAVWDFRLDKDELGEIAKLDQGK 264



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>DKGA_YERPE (Q8ZI40) 2,5-diketo-D-gluconic acid reductase A (EC 1.1.1.274)|
           (2,5-DKG reductase A) (2,5-DKGR A) (25DKGR-A) (AKR5C)
          Length = 277

 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 36/112 (32%), Positives = 56/112 (50%)
 Frame = -1

Query: 546 QQRKLREFCRGKGIQLCAYSPLGAKGTHWGSDAVMDAGVLQDIAASRGKSVAQVCLRWVY 367
           QQR+L  +     I   ++SPL       G   V D  +++ +A    K+ AQ+ +RW  
Sbjct: 168 QQRQLHAWNATHHIATESWSPLAQ-----GGKGVFDQEIIRKLAQQYNKTPAQIVIRWHL 222

Query: 366 EQGDCLIVKSFDEARMRENLDVDGWELTEEERRRIAEIPQRKINLGKRYVSD 211
           + G  +I KS   AR+REN +V  ++L +EE   I      K++ GKR   D
Sbjct: 223 DSGLIVIPKSVTPARIRENFEVFDFKLQKEELLAIT-----KLDCGKRLGPD 269



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>DKGA_CORSC (P06632) 2,5-diketo-D-gluconic acid reductase A (EC 1.1.1.274)|
           (2,5-DKG reductase A) (2,5-DKGR A) (25DKGR-A) (AKR5C)
          Length = 277

 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 38/114 (33%), Positives = 59/114 (51%), Gaps = 1/114 (0%)
 Frame = -1

Query: 546 QQRKLREFCRGKGIQLCAYSPLG-AKGTHWGSDAVMDAGVLQDIAASRGKSVAQVCLRWV 370
           QQR++ ++     +++ ++ PLG  K   +G++ V  A      AA+ GK+ AQ  LRW 
Sbjct: 168 QQREITDWAAAHDVKIESWGPLGQGKYDLFGAEPVTAA------AAAHGKTPAQAVLRWH 221

Query: 369 YEQGDCLIVKSFDEARMRENLDVDGWELTEEERRRIAEIPQRKINLGKRYVSDH 208
            ++G  +  KS    R+ ENLDV  ++LT+ E   IA I       G   VS H
Sbjct: 222 LQKGFVVFPKSVRRERLEENLDVFDFDLTDTE---IAAIDAMDPGDGSGRVSAH 272



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>XYL1_CANTR (O13283) NAD(P)H-dependent D-xylose reductase I,II (EC 1.1.1.-)|
           (XR)
          Length = 324

 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 35/116 (30%), Positives = 59/116 (50%), Gaps = 7/116 (6%)
 Frame = -1

Query: 546 QQRKLREFCRGKGIQLCAYSPLGAKG-------THWGSDAVMDAGVLQDIAASRGKSVAQ 388
           QQ KL E+ +  GI +  YS  G +            +  + +   ++ IA   GKS AQ
Sbjct: 201 QQPKLIEYVQKAGIAITGYSSFGPQSFLELESKRALNTPTLFEHETIKLIADKHGKSPAQ 260

Query: 387 VCLRWVYEQGDCLIVKSFDEARMRENLDVDGWELTEEERRRIAEIPQRKINLGKRY 220
           V LRW  ++   +I KS +  R+ +NL V  ++LT+++   IA     K+++G R+
Sbjct: 261 VLLRWATQRNIAVIPKSNNPERLAQNLSVVDFDLTKDDLDNIA-----KLDIGLRF 311



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>XYL1_CANTE (O74237) NAD(P)H-dependent D-xylose reductase (EC 1.1.1.-) (XR)|
          Length = 322

 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 35/116 (30%), Positives = 59/116 (50%), Gaps = 7/116 (6%)
 Frame = -1

Query: 546 QQRKLREFCRGKGIQLCAYSPLGAK-------GTHWGSDAVMDAGVLQDIAASRGKSVAQ 388
           QQ KL EF +  G+ + AYS  G +       G    +  +     ++ IAA   K+ A+
Sbjct: 199 QQPKLIEFAQKAGVTITAYSSFGPQSFVEMNQGRALNTPTLFAHDTIKAIAAKYNKTPAE 258

Query: 387 VCLRWVYEQGDCLIVKSFDEARMRENLDVDGWELTEEERRRIAEIPQRKINLGKRY 220
           V LRW  ++G  +I KS    R+ +N   + ++LT+E+   IA     K+++G R+
Sbjct: 259 VLLRWAAQRGIAVIPKSNLPERLVQNRSFNTFDLTKEDFEEIA-----KLDIGLRF 309



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>YOF5_CAEEL (Q09632) Probable oxidoreductase ZK1290.5 in chromosome II (EC|
           1.-.-.-)
          Length = 321

 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 33/90 (36%), Positives = 48/90 (53%)
 Frame = -1

Query: 543 QRKLREFCRGKGIQLCAYSPLGAKGTHWGSDAVMDAGVLQDIAASRGKSVAQVCLRWVYE 364
           Q  L+ +C   GI    Y PL AKG +      ++   L  IA+   KS AQ+CLRW  +
Sbjct: 174 QADLKNYCDELGILTMGYCPL-AKGKY------LEDETLCKIASKYQKSPAQICLRWSIQ 226

Query: 363 QGDCLIVKSFDEARMRENLDVDGWELTEEE 274
           Q    + KS D  R++EN +V  +EL+ E+
Sbjct: 227 QNVPTVPKSTDCRRLKENTNVFDFELSAED 256



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>P100_LEIMA (P22045) Probable reductase (EC 1.1.-.-)|
          Length = 284

 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 37/111 (33%), Positives = 51/111 (45%)
 Frame = -1

Query: 543 QRKLREFCRGKGIQLCAYSPLGAKGTHWGSDAVMDAGVLQDIAASRGKSVAQVCLRWVYE 364
           Q  LR FC  K I++ A+SPLG          ++   +L  I A   K+ AQV LRW  +
Sbjct: 180 QADLRAFCDAKQIKVEAWSPLG-------QGKLLSNPILSAIGAKYNKTAAQVILRWNIQ 232

Query: 363 QGDCLIVKSFDEARMRENLDVDGWELTEEERRRIAEIPQRKINLGKRYVSD 211
           +    I KS    R+ EN D+  +EL  E+   I       +N   RY  D
Sbjct: 233 KNLITIPKSVHRERIEENADIFDFELGAEDVMSI-----DALNTNSRYGPD 278



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>XYL1_CANSH (Q9P430) NAD(P)H-dependent D-xylose reductase (EC 1.1.1.-) (XR)|
          Length = 323

 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 33/105 (31%), Positives = 55/105 (52%), Gaps = 7/105 (6%)
 Frame = -1

Query: 546 QQRKLREFCRGKGIQLCAYSPLGAK-------GTHWGSDAVMDAGVLQDIAASRGKSVAQ 388
           QQ KL E+ +  GI + AYS  G +       G    +  + +  V++ IAA   K  A+
Sbjct: 200 QQPKLIEYAQKVGITVTAYSSFGPQSFVEMNQGRALNTPTLFEHDVIKAIAAKHNKVPAE 259

Query: 387 VCLRWVYEQGDCLIVKSFDEARMRENLDVDGWELTEEERRRIAEI 253
           V LRW  ++G  +I KS    R+ +N   + +ELT+E+   I+++
Sbjct: 260 VLLRWSAQRGIAVIPKSNLPERLVQNRSFNDFELTKEDFEEISKL 304



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>AKC1H_RAT (P51652) Aldo-keto reductase family 1 member C18 (EC 1.1.-.-)|
           (20-alpha-hydroxysteroid dehydrogenase) (EC 1.1.1.149)
           (20-alpha-HSD) (HSD1)
          Length = 323

 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 30/94 (31%), Positives = 51/94 (54%), Gaps = 4/94 (4%)
 Frame = -1

Query: 543 QRKLREFCRGKGIQLCAYSPLGAKGTHW----GSDAVMDAGVLQDIAASRGKSVAQVCLR 376
           Q KL  +C+   I L AY  LG +   +     +  ++D  +L  +A    ++ A + LR
Sbjct: 199 QSKLLAYCKMNDIVLVAYGALGTQRYKYCINEDTPVLLDDPILCTMAKKYKRTPALIALR 258

Query: 375 WVYEQGDCLIVKSFDEARMRENLDVDGWELTEEE 274
           +  E+G   +VKSF+E R+RENL V  ++L  ++
Sbjct: 259 YQLERGIVTLVKSFNEERIRENLQVFDFQLASDD 292



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>XYL1_PICGU (O94735) NADPH-dependent D-xylose reductase (EC 1.1.1.-) (XR)|
          Length = 317

 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 32/105 (30%), Positives = 57/105 (54%), Gaps = 7/105 (6%)
 Frame = -1

Query: 546 QQRKLREFCRGKGIQLCAYSPLGAKG-THWGSDAVMDA------GVLQDIAASRGKSVAQ 388
           QQ +L E+ + +GI + AYS  G +         V D        V++ +A    K+ AQ
Sbjct: 194 QQPRLVEYVQSQGIAITAYSSFGPQSFVELDHPRVKDVKPLFEHDVIKSVAGKVKKTPAQ 253

Query: 387 VCLRWVYEQGDCLIVKSFDEARMRENLDVDGWELTEEERRRIAEI 253
           V LRW  ++G  +I KS +  R+  NL V+ ++L++E+ + I+++
Sbjct: 254 VLLRWATQRGLAVIPKSNNPDRLLSNLKVNDFDLSQEDFQEISKL 298



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>XYL1_CANPA (Q6Y0Z3) NADH-dependent D-xylose reductase (EC 1.1.1.175) (XR)|
          Length = 324

 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 33/104 (31%), Positives = 55/104 (52%), Gaps = 7/104 (6%)
 Frame = -1

Query: 543 QRKLREFCRGKGIQLCAYSPLGAKG-------THWGSDAVMDAGVLQDIAASRGKSVAQV 385
           Q KL E+ +   IQ+  YS  G +            +  +++   ++ IA   GKS AQV
Sbjct: 202 QPKLVEYVQLHDIQITGYSSFGPQSFLEMDLKRALDTPVLLEEPTVKSIADKHGKSPAQV 261

Query: 384 CLRWVYEQGDCLIVKSFDEARMRENLDVDGWELTEEERRRIAEI 253
            LR+  ++G  +I +S    RM +NL V  +ELT+++ + IAE+
Sbjct: 262 LLRYQTQRGIAVIPRSNSPDRMAQNLSVIDFELTQDDLQAIAEL 305



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>DKGB_CORSS (P15339) 2,5-diketo-D-gluconic acid reductase B (EC 1.1.1.274)|
           (2,5-DKG reductase B) (2,5-DKGR B) (25DKGR-B) (AKR5D)
          Length = 276

 Score = 49.3 bits (116), Expect = 7e-06
 Identities = 33/102 (32%), Positives = 52/102 (50%)
 Frame = -1

Query: 543 QRKLREFCRGKGIQLCAYSPLGAKGTHWGSDAVMDAGVLQDIAASRGKSVAQVCLRWVYE 364
           Q  LR F    GI+  ++SPL  +        ++   +LQ++A   G +  QV LRW  +
Sbjct: 170 QAALRAFHDEHGIRTESWSPLARRSE------LLTEQLLQELAVVYGVTPTQVVLRWHVQ 223

Query: 363 QGDCLIVKSFDEARMRENLDVDGWELTEEERRRIAEIPQRKI 238
            G   I KS D  R REN DV G+ LT ++   I+ + + ++
Sbjct: 224 LGSTPIPKSADPDRQRENADVFGFALTADQVDAISGLERGRL 265



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>MORA_PSEPU (Q02198) Morphine 6-dehydrogenase (EC 1.1.1.218) (Naloxone|
           reductase)
          Length = 295

 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 32/103 (31%), Positives = 51/103 (49%), Gaps = 6/103 (5%)
 Frame = -1

Query: 543 QRKLREFCRGKGIQLCAYSPLGAK------GTHWGSDAVMDAGVLQDIAASRGKSVAQVC 382
           Q+ L    R  GI   A+SP+G          H G    +   V+  IA + G+S AQV 
Sbjct: 171 QKPLLAKNRALGIVTEAWSPIGGAINDGDGDNHGGRKHPLTDPVITTIAEAHGRSAAQVI 230

Query: 381 LRWVYEQGDCLIVKSFDEARMRENLDVDGWELTEEERRRIAEI 253
           LRW ++     I KS +  R+ +N+DV  + L++ E  ++ E+
Sbjct: 231 LRWHFQNDVVAIPKSVNPERIAKNIDVFDFALSDAEMAQLDEL 273



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>AKC1H_MOUSE (Q8K023) Aldo-keto reductase family 1 member C18 (EC 1.1.-.-)|
           (20-alpha-hydroxysteroid dehydrogenase) (EC 1.1.1.149)
           (20-alpha-HSD)
          Length = 323

 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 28/96 (29%), Positives = 51/96 (53%), Gaps = 4/96 (4%)
 Frame = -1

Query: 543 QRKLREFCRGKGIQLCAYSPLGAKGTHW----GSDAVMDAGVLQDIAASRGKSVAQVCLR 376
           Q KL  +C+   I L AY  LG +   +     +  ++D  VL  +A    ++ A + LR
Sbjct: 199 QSKLLAYCKMNDIVLVAYGALGTQRYKYCINEDTPVLLDDPVLCAMAKKYKRTPALIALR 258

Query: 375 WVYEQGDCLIVKSFDEARMRENLDVDGWELTEEERR 268
           +  ++G   + KSF+E R+REN+ V  ++L  ++ +
Sbjct: 259 YQLDRGIVALAKSFNEERIRENMQVFDFQLASDDMK 294



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>XYL1_TRIRE (Q876L8) NAD(P)H-dependent D-xylose reductase (EC 1.1.1.-) (XR)|
          Length = 324

 Score = 45.8 bits (107), Expect = 8e-05
 Identities = 31/105 (29%), Positives = 52/105 (49%), Gaps = 7/105 (6%)
 Frame = -1

Query: 546 QQRKLREFCRGKGIQLCAYSPLGAKG-------THWGSDAVMDAGVLQDIAASRGKSVAQ 388
           QQ  L    + +GI + AYS  G  G              +MD+ V++ +A    ++ AQ
Sbjct: 198 QQPDLVSLAQTEGIVVTAYSSFGPTGFMELDMPRAKSVAPLMDSPVIKALADKHRRTPAQ 257

Query: 387 VCLRWVYEQGDCLIVKSFDEARMRENLDVDGWELTEEERRRIAEI 253
           V LRW  ++G  +I K+     M +NLD   ++L  E+  +IA++
Sbjct: 258 VLLRWATQRGIAVIPKTSRPEVMAQNLDNTSFDLDSEDLAKIADM 302



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>XYL1_KLULA (P49378) NAD(P)H-dependent D-xylose reductase (EC 1.1.1.-) (XR)|
          Length = 329

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 29/107 (27%), Positives = 53/107 (49%), Gaps = 8/107 (7%)
 Frame = -1

Query: 543 QRKLREFCRGKGIQLCAYSPLGAKG-------THWGSDAVMDAGVLQDIAASRGKSVAQV 385
           Q +L ++ +  GIQ+ AYS  G              +  + +   ++ IA+    +  QV
Sbjct: 204 QERLIKYVKNAGIQVVAYSSFGPVSFLELENKKALNTPTLFEHDTIKSIASKHKVTPQQV 263

Query: 384 CLRWVYEQGDCLIVKSFDEARMRENLDV-DGWELTEEERRRIAEIPQ 247
            LRW  + G  +I KS  + R+ +NL + D   LT++E ++I+ + Q
Sbjct: 264 LLRWATQNGIAIIPKSSKKERLLDNLRINDALTLTDDELKQISGLNQ 310



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>GRE3_YEAST (P38715) NADPH-dependent aldose reductase GRE3 (EC 1.1.1.21)|
           (NADPH-dependent aldo-keto reductase GRE3)
           (NADPH-dependent methylglyoxal reductase GRE3) (EC
           1.1.1.-) (Xylose reductase) (EC 1.1.1.-) (Genes de
           respuesta a estres protein 3)
          Length = 327

 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 30/106 (28%), Positives = 56/106 (52%), Gaps = 9/106 (8%)
 Frame = -1

Query: 543 QRKLREFCRGKGIQLCAYSPLGAKG-------THWGSDAVMDAGVLQDIAASR-GKSVAQ 388
           Q  L EFC+   IQ+ AYS  G +            +  + +  V++ ++ +  G + +Q
Sbjct: 201 QEHLVEFCKLHDIQVVAYSSFGPQSFIEMDLQLAKTTPTLFENDVIKKVSQNHPGSTTSQ 260

Query: 387 VCLRWVYEQGDCLIVKSFDEARMRENLDVD-GWELTEEERRRIAEI 253
           V LRW  ++G  +I KS  + R+  NL+++  + LTE+E + I+ +
Sbjct: 261 VLLRWATQRGIAVIPKSSKKERLLGNLEIEKKFTLTEQELKDISAL 306



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>DTDH_MUCMU (Q01213) 4-dihydromethyl-trisporate dehydrogenase (EC 1.1.1.-)|
           (4-dihydromethyl-TA dehydrogenase)
          Length = 321

 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 27/100 (27%), Positives = 51/100 (51%), Gaps = 6/100 (6%)
 Frame = -1

Query: 543 QRKLREFCRGKGIQLCAYSPLGAKG----THWGSD--AVMDAGVLQDIAASRGKSVAQVC 382
           Q +L ++ + +GIQ+ AYS  G       T  G    ++++   ++ +A     S  QV 
Sbjct: 199 QERLVKWVKEQGIQITAYSSFGPTSYVDLTESGKTYTSLLEHASVKSVADKHNVSTGQVL 258

Query: 381 LRWVYEQGDCLIVKSFDEARMRENLDVDGWELTEEERRRI 262
           LRW  ++   +I KS +  RM+ NL++   +L  E+ + +
Sbjct: 259 LRWALDREFAVIPKSVNAGRMKANLEILDIKLDAEDNKTL 298



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>YPR1_YEAST (Q12458) Putative reductase 1 (EC 1.1.1.-)|
          Length = 312

 Score = 43.1 bits (100), Expect = 5e-04
 Identities = 30/109 (27%), Positives = 56/109 (51%)
 Frame = -1

Query: 543 QRKLREFCRGKGIQLCAYSPLGAKGTHWGSDAVMDAGVLQDIAASRGKSVAQVCLRWVYE 364
           Q +L  FC+ KGI + AYSP G+      +  ++    + D+A   G   AQ+ + W  +
Sbjct: 202 QDELIAFCKEKGIVVEAYSPFGS-----ANAPLLKEQAIIDMAKKHGVEPAQLIISWSIQ 256

Query: 363 QGDCLIVKSFDEARMRENLDVDGWELTEEERRRIAEIPQRKINLGKRYV 217
           +G  ++ KS +  R+  N  +  + L E++ + I+ +   K++  KR V
Sbjct: 257 RGYVVLAKSVNPERIVSNFKI--FTLPEDDFKTISNL--SKVHGTKRVV 301



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>AK1D1_RAT (P31210) 3-oxo-5-beta-steroid 4-dehydrogenase (EC 1.3.99.6)|
           (Delta(4)-3-ketosteroid 5-beta-reductase) (Aldo-keto
           reductase family 1 member D1)
          Length = 326

 Score = 42.7 bits (99), Expect = 7e-04
 Identities = 31/110 (28%), Positives = 53/110 (48%), Gaps = 4/110 (3%)
 Frame = -1

Query: 501 LCAYSPLGA-KGTHW---GSDAVMDAGVLQDIAASRGKSVAQVCLRWVYEQGDCLIVKSF 334
           + AYSPLG  +   W    S  ++   +L  +     K+ AQ+ LR+  ++G  +I KS 
Sbjct: 216 IVAYSPLGTCRNPLWVNVSSPPLLKDELLTSLGKKYNKTQAQIVLRFDIQRGLVVIPKST 275

Query: 333 DEARMRENLDVDGWELTEEERRRIAEIPQRKINLGKRYVSDHGPYKSLEE 184
              R++EN  +  + LT+EE + I  + +    +     SDH  Y   +E
Sbjct: 276 TPERIKENFQIFDFSLTKEEMKDIEALNKNVRFVEMLMWSDHPEYPFHDE 325



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>YDG7_SCHPO (Q10494) Probable oxidoreductase C26F1.07 in chromosome I (EC|
           1.-.-.-)
          Length = 321

 Score = 41.6 bits (96), Expect = 0.001
 Identities = 29/90 (32%), Positives = 47/90 (52%), Gaps = 4/90 (4%)
 Frame = -1

Query: 510 GIQLCAYSPLGAKGTHWGS--DAVMDAGVLQDIAASRGKSV--AQVCLRWVYEQGDCLIV 343
           GI + AYSP G + T + S    +++   +Q IA S+G+ V  A + + W   +G  +I 
Sbjct: 209 GIHVTAYSPFGNQNTIYESKIPKLIEHETIQKIAKSKGEGVTGATIAVSWAITRGTSVIP 268

Query: 342 KSFDEARMRENLDVDGWELTEEERRRIAEI 253
           KS +E R++ N       LT+E+   I  I
Sbjct: 269 KSVNEQRIKSNFKY--IPLTKEDMDEINSI 296



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>GCY_YEAST (P14065) GCY protein (EC 1.1.1.-)|
          Length = 312

 Score = 41.6 bits (96), Expect = 0.001
 Identities = 30/102 (29%), Positives = 52/102 (50%), Gaps = 1/102 (0%)
 Frame = -1

Query: 543 QRKLREFCRGKGIQLCAYSPLGAKGTHWGSDA-VMDAGVLQDIAASRGKSVAQVCLRWVY 367
           Q +L  FC+ KGI + AYSPLG+      +DA ++   V+ +IA         V + W  
Sbjct: 202 QDELINFCKSKGIVVEAYSPLGS------TDAPLLKEPVILEIAKKNNVQPGHVVISWHV 255

Query: 366 EQGDCLIVKSFDEARMRENLDVDGWELTEEERRRIAEIPQRK 241
           ++G  ++ KS +  R++ N  +  + L+ E+   I  I + K
Sbjct: 256 QRGYVVLPKSVNPDRIKTNRKI--FTLSTEDFEAINNISKEK 295



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>ALDX_SPOSA (P27800) Aldehyde reductase 1 (EC 1.1.1.2) (Aldehyde reductase I)|
           (Alcohol dehydrogenase [NADP+]) (ALR)
          Length = 322

 Score = 38.5 bits (88), Expect = 0.012
 Identities = 32/99 (32%), Positives = 45/99 (45%), Gaps = 9/99 (9%)
 Frame = -1

Query: 519 RGKGIQLCAYSPLGAKGTHWGSDAVMDAGVLQDIAASRGKSVAQVCLRWVYEQGDCLIVK 340
           + K I + AYSPLG      G+  ++    ++ IA   G + AQV + W    G  +I K
Sbjct: 199 KAKNIHITAYSPLGNNTV--GAPLLVQHPEIKRIAEKNGCTPAQVLIAWAIVGGHSVIPK 256

Query: 339 SFDEARMRENL--------DVDG-WELTEEERRRIAEIP 250
           S   +R+ EN         DVD   +L E   RR   IP
Sbjct: 257 SVTPSRIGENFKQVSLSQEDVDAVSKLGEGSGRRRYNIP 295



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>DKGB_ECOLI (P30863) 2,5-diketo-D-gluconic acid reductase B (EC 1.1.1.274)|
           (2,5-DKG reductase B) (2,5-DKGR B) (25DKGR-B) (AKR5D)
          Length = 267

 Score = 37.7 bits (86), Expect = 0.021
 Identities = 34/124 (27%), Positives = 51/124 (41%)
 Frame = -1

Query: 546 QQRKLREFCRGKGIQLCAYSPLGAKGTHWGSDAVMDAGVLQDIAASRGKSVAQVCLRWVY 367
           Q RK+  + +  GI + +Y  L          A+ D  V+  IAA    + AQV L W  
Sbjct: 160 QNRKVVAWAKQHGIHITSYMTLAY------GKALKDE-VIARIAAKHNATPAQVILAWAM 212

Query: 366 EQGDCLIVKSFDEARMRENLDVDGWELTEEERRRIAEIPQRKINLGKRYVSDHGPYKSLE 187
            +G  +I  S     +  NL     +L  E+++ IA      ++   R VS  G    L 
Sbjct: 213 GEGYSVIPSSTKRKNLESNLKAQNLQLDAEDKKAIA-----ALDCNDRLVSPEG----LA 263

Query: 186 ELWD 175
             WD
Sbjct: 264 PEWD 267



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>DKGB_ECO57 (Q8X7Z7) 2,5-diketo-D-gluconic acid reductase B (EC 1.1.1.274)|
           (2,5-DKG reductase B) (2,5-DKGR B) (25DKGR-B) (AKR5D)
          Length = 267

 Score = 37.7 bits (86), Expect = 0.021
 Identities = 34/124 (27%), Positives = 51/124 (41%)
 Frame = -1

Query: 546 QQRKLREFCRGKGIQLCAYSPLGAKGTHWGSDAVMDAGVLQDIAASRGKSVAQVCLRWVY 367
           Q RK+  + +  GI + +Y  L          A+ D  V+  IAA    + AQV L W  
Sbjct: 160 QNRKVVAWAKQHGIHITSYMTLAY------GKALKDE-VIARIAAKHNATPAQVILAWAM 212

Query: 366 EQGDCLIVKSFDEARMRENLDVDGWELTEEERRRIAEIPQRKINLGKRYVSDHGPYKSLE 187
            +G  +I  S     +  NL     +L  E+++ IA      ++   R VS  G    L 
Sbjct: 213 GEGYSVIPSSTKRENLESNLKAQNLQLDAEDKKAIA-----ALDCNDRLVSPEG----LA 263

Query: 186 ELWD 175
             WD
Sbjct: 264 PEWD 267



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>YEAE_ECOLI (P76234) Hypothetical protein yeaE|
          Length = 284

 Score = 36.2 bits (82), Expect = 0.062
 Identities = 28/88 (31%), Positives = 44/88 (50%), Gaps = 1/88 (1%)
 Frame = -1

Query: 534 LREFCRGKGIQLCAYSPLGAKGTHWGSDAVMDAGVLQDIAASRGKSVAQVCLRWVY-EQG 358
           L  +C+ + + + AYSPL   G     + ++   V+ +IA +   S AQV L WV   QG
Sbjct: 179 LLPWCQQQQMPVMAYSPLAQAGRL--RNGLLKNAVVNEIAHAHNISAAQVLLAWVISHQG 236

Query: 357 DCLIVKSFDEARMRENLDVDGWELTEEE 274
              I K+   A +++N  V   EL+  E
Sbjct: 237 VMAIPKAATIAHVQQNAAVLEVELSSAE 264



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>DKGB_SALTY (Q8ZRM7) 2,5-diketo-D-gluconic acid reductase B (EC 1.1.1.274)|
           (2,5-DKG reductase B) (2,5-DKGR B) (25DKGR-B) (AKR5D)
          Length = 267

 Score = 34.7 bits (78), Expect = 0.18
 Identities = 33/124 (26%), Positives = 50/124 (40%)
 Frame = -1

Query: 546 QQRKLREFCRGKGIQLCAYSPLGAKGTHWGSDAVMDAGVLQDIAASRGKSVAQVCLRWVY 367
           Q RK+ ++ +  GI + +Y  L          A+ D  V+  IAA    + AQV L W  
Sbjct: 160 QNRKVVDWAKAHGIHITSYMTLAY------GKALKDE-VIARIAAKHNATPAQVILAWAM 212

Query: 366 EQGDCLIVKSFDEARMRENLDVDGWELTEEERRRIAEIPQRKINLGKRYVSDHGPYKSLE 187
            +G  +I  S     +  +L      L  E++  IA      ++   R VS  G    L 
Sbjct: 213 GEGYSVIPSSTRRENLASSLLAQDLHLDAEDKNAIA-----ALDCNDRLVSPEG----LA 263

Query: 186 ELWD 175
             WD
Sbjct: 264 PAWD 267



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>YDBC_ECOLI (P25906) Putative oxidoreductase ydbC (EC 1.-.-.-)|
          Length = 286

 Score = 34.3 bits (77), Expect = 0.23
 Identities = 20/63 (31%), Positives = 32/63 (50%), Gaps = 2/63 (3%)
 Frame = -1

Query: 459 GSDAVMDAGVLQDIAASRGKSVAQVCLRWVYEQGD--CLIVKSFDEARMRENLDVDGWEL 286
           G    + +  L D+AAS G +  QV L W+ ++     LI  +   A +REN+  +   L
Sbjct: 213 GGFTPLQSSTLSDVAASLGATPMQVALAWLLQRSPNILLIPGTSSVAHLRENMAAEKLHL 272

Query: 285 TEE 277
           +EE
Sbjct: 273 SEE 275



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>YJ66_YEAST (P47137) Probable oxidoreductase YJR096W (EC 1.-.-.-)|
          Length = 282

 Score = 34.3 bits (77), Expect = 0.23
 Identities = 23/94 (24%), Positives = 47/94 (50%), Gaps = 2/94 (2%)
 Frame = -1

Query: 543 QRKLREFCRGKGIQLCAYSPL--GAKGTHWGSDAVMDAGVLQDIAASRGKSVAQVCLRWV 370
           +++L ++C+ KG+ + A++PL  G K T+           L  +     ++  QV +RW 
Sbjct: 179 RQELADYCKSKGLVVEAFAPLCHGYKMTN---------PDLLKVCKEVDRNPGQVLIRWS 229

Query: 369 YEQGDCLIVKSFDEARMRENLDVDGWELTEEERR 268
            + G   + K+    R+  NL    +EL++E+ +
Sbjct: 230 LQHGYLPLPKTKTVKRLEGNLAAYNFELSDEQMK 263



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>MOVP_TAV (P23626) Movement protein (MP) (Protein 3A)|
          Length = 277

 Score = 32.7 bits (73), Expect = 0.68
 Identities = 27/82 (32%), Positives = 42/82 (51%), Gaps = 9/82 (10%)
 Frame = +1

Query: 82  VPQSTSHPWPRMTNAGTPAGQSVSTGYSYLAVPELLEGLVRPVVGHVALAEVDLALRDLG 261
           VP++TS+   R   +G  AG+  S G  Y++VP++L  + R V    A   + + L DLG
Sbjct: 59  VPETTSNLLTRWFVSGYEAGELPSKG--YMSVPQVLCAVTRTVTSD-AEGSLRIYLADLG 115

Query: 262 DP---------AALLLRELPAV 300
           D           +L  R+LPA+
Sbjct: 116 DKERAPIDAQVVSLHNRDLPAI 137



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>DXS_CHLMU (Q9PK62) 1-deoxy-D-xylulose-5-phosphate synthase (EC 2.2.1.7)|
           (1-deoxyxylulose-5-phosphate synthase) (DXP synthase)
           (DXPS)
          Length = 632

 Score = 32.7 bits (73), Expect = 0.68
 Identities = 31/93 (33%), Positives = 45/93 (48%), Gaps = 5/93 (5%)
 Frame = +1

Query: 226 LAEVDLALRDLGDPAALLLRELPAVHVQVLPHPG-----LVEALDDEAVPLLVHPPQAHL 390
           L +VD+AL+ L  P    L E   +H  V P  G     L+ AL  EAV  L +P   H+
Sbjct: 224 LHKVDIALKSLSHP----LFEQFGIHY-VGPFDGHNIKKLIPAL--EAVKGLPYPVLFHV 276

Query: 391 RHALAPGRGDVLQDAGVHHGVAAPVRALGPKRR 489
             A   G  +  +D  ++HGV A  +   PK++
Sbjct: 277 CTAKGNGLAEAEKDPALYHGVKAYFKNHSPKKK 309



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>ARA1_YEAST (P38115) D-arabinose dehydrogenase [NAD(P)+] heavy chain (EC|
           1.1.1.117)
          Length = 344

 Score = 32.7 bits (73), Expect = 0.68
 Identities = 23/100 (23%), Positives = 49/100 (49%)
 Frame = -1

Query: 543 QRKLREFCRGKGIQLCAYSPLGAKGTHWGSDAVMDAGVLQDIAASRGKSVAQVCLRWVYE 364
           Q +LR+FC    I L AYSPLG+ G        +   +++ +A     +   + + +   
Sbjct: 223 QMELRKFCFMHDILLTAYSPLGSHGA-----PNLKIPLVKKLAEKYNVTGNDLLISYHIR 277

Query: 363 QGDCLIVKSFDEARMRENLDVDGWELTEEERRRIAEIPQR 244
           QG  +I +S +  R+  +++     LT++E + + +  ++
Sbjct: 278 QGTIVIPRSLNPVRISSSIEFA--SLTKDELQELNDFGEK 315



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>GNDS_MOUSE (Q03385) Ral guanine nucleotide dissociation stimulator (RalGEF)|
           (RalGDS)
          Length = 852

 Score = 32.3 bits (72), Expect = 0.89
 Identities = 42/161 (26%), Positives = 67/161 (41%), Gaps = 9/161 (5%)
 Frame = +1

Query: 19  SFTETQHIVLLIYSKGNQCKAVPQSTSHP--WPRMTNAGTPAGQSVSTGYSYLA--VPEL 186
           +FT TQ ++ L++ +  +C A+  S+ +    P  +  G P  Q  +   S L   + + 
Sbjct: 94  AFTTTQQVLDLLFKRYGRCDALTASSRYGCILPYSSEDGGPQDQLKNAISSILGTWLDQY 153

Query: 187 LEGLVRP-----VVGHVALAEVDLALRDLGDPAALLLRELPAVHVQVLPHPGLVEALDDE 351
            E   +P     +   VA  ++++   DL   A LLL +L  +     P     EAL   
Sbjct: 154 SEDFCQPPDFPCLKQLVAYVQLNMPGSDLERRAHLLLAQLEDLE----PSEAESEAL--S 207

Query: 352 AVPLLVHPPQAHLRHALAPGRGDVLQDAGVHHGVAAPVRAL 474
             P+L   P + L  AL      V+    V    AAPV  L
Sbjct: 208 PAPVLSLKPASQLEPALLLTPSQVVTSTPVREPAAAPVPVL 248



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>DKGB_YERPE (Q8ZH36) 2,5-diketo-D-gluconic acid reductase B (EC 1.1.1.274)|
           (2,5-DKG reductase B) (2,5-DKGR B) (25DKGR-B) (AKR5D)
          Length = 267

 Score = 32.0 bits (71), Expect = 1.2
 Identities = 23/80 (28%), Positives = 36/80 (45%)
 Frame = -1

Query: 546 QQRKLREFCRGKGIQLCAYSPLGAKGTHWGSDAVMDAGVLQDIAASRGKSVAQVCLRWVY 367
           Q R + +F +  GI + +Y  L      +G    +   V++ IA   G + AQV L W  
Sbjct: 160 QNRNVVDFAKQNGIAVTSYMTLA-----YGK--ALAEPVIKTIAEQHGATPAQVILSWAM 212

Query: 366 EQGDCLIVKSFDEARMRENL 307
           + G  +I  S   A +  NL
Sbjct: 213 QLGYGVIPSSTKAANLASNL 232



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>MIB2_HUMAN (Q96AX9) Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb|
           homolog 2) (Zinc finger ZZ type with ankyrin repeat
           domain protein 1) (Skeletrophin) (Novelzin) (Novel zinc
           finger protein) (Putative NF-kappa-B-activating protein
           002N)
          Length = 1013

 Score = 32.0 bits (71), Expect = 1.2
 Identities = 18/41 (43%), Positives = 23/41 (56%)
 Frame = -3

Query: 244 QDQPRQALRVRPRALQVPRGALGRRDMSSLWRPTGLPAYQR 122
           Q Q  QA  ++PR+L+  R A GR D S   RPT  P+  R
Sbjct: 11  QSQSFQASGLQPRSLKAARRATGRPDRSRAARPTTDPSAHR 51



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>MURA1_STRR6 (Q8DNE8) UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1 (EC|
           2.5.1.7) (Enoylpyruvate transferase 1)
           (UDP-N-acetylglucosamine enolpyruvyl transferase 1) (EPT
           1)
          Length = 427

 Score = 32.0 bits (71), Expect = 1.2
 Identities = 16/42 (38%), Positives = 22/42 (52%)
 Frame = +1

Query: 202 RPVVGHVALAEVDLALRDLGDPAALLLRELPAVHVQVLPHPG 327
           RP++  +    V++   D G      L  L AVHV+ LPHPG
Sbjct: 264 RPLIAKLLEMGVEVIEEDEGIRVRSQLENLKAVHVKTLPHPG 305



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>MURA1_STRPN (Q97NQ4) UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1 (EC|
           2.5.1.7) (Enoylpyruvate transferase 1)
           (UDP-N-acetylglucosamine enolpyruvyl transferase 1) (EPT
           1)
          Length = 427

 Score = 32.0 bits (71), Expect = 1.2
 Identities = 16/42 (38%), Positives = 22/42 (52%)
 Frame = +1

Query: 202 RPVVGHVALAEVDLALRDLGDPAALLLRELPAVHVQVLPHPG 327
           RP++  +    V++   D G      L  L AVHV+ LPHPG
Sbjct: 264 RPLIAKLLEMGVEVIEEDEGIRVRSQLENLKAVHVKTLPHPG 305



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>MOVP_PSVJ (P22117) Movement protein (MP) (Protein 3A)|
          Length = 288

 Score = 32.0 bits (71), Expect = 1.2
 Identities = 20/61 (32%), Positives = 34/61 (55%)
 Frame = +1

Query: 82  VPQSTSHPWPRMTNAGTPAGQSVSTGYSYLAVPELLEGLVRPVVGHVALAEVDLALRDLG 261
           VP++TS+   +    G  AG+  S G  Y+ +P++L  + R V  + A   +++ L DLG
Sbjct: 59  VPETTSNKVAQWFKTGYEAGKLPSKG--YMIIPQVLCAVTRTVTSN-AEGSLEIYLADLG 115

Query: 262 D 264
           D
Sbjct: 116 D 116



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>RPOA1_THECE (P31813) DNA-directed RNA polymerase subunit A' (EC 2.7.7.6)|
          Length = 905

 Score = 32.0 bits (71), Expect = 1.2
 Identities = 19/70 (27%), Positives = 37/70 (52%), Gaps = 2/70 (2%)
 Frame = +1

Query: 157 GYSYLAVPELLEGLV-RPVVGHVALAEVDLALRDLG-DPAALLLRELPAVHVQVLPHPGL 330
           G++Y+   +LL G + +   G      +D+ +R+ G + A   L ++  + + V+ H G 
Sbjct: 607 GFTYILNGKLLSGAIDKTAYGREDGKLLDIIVREYGVERARQFLDQVTKLAIWVITHKGF 666

Query: 331 VEALDDEAVP 360
             A+DDE +P
Sbjct: 667 TTAIDDEDLP 676



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>ALGC_PSEPK (Q88C93) Phosphomannomutase/phosphoglucomutase (EC 5.4.2.8) (EC|
           5.4.2.2) (PMM / PGM)
          Length = 463

 Score = 31.2 bits (69), Expect = 2.0
 Identities = 24/84 (28%), Positives = 38/84 (45%)
 Frame = +1

Query: 181 ELLEGLVRPVVGHVALAEVDLALRDLGDPAALLLRELPAVHVQVLPHPGLVEALDDEAVP 360
           E+L+   + +VG V LA+    + D G+ AA ++             P L+EAL  E +P
Sbjct: 154 EILDRYFKQIVGDVKLAKKLKVVVDCGNGAAGVVA------------PQLIEALGCEVIP 201

Query: 361 LLVHPPQAHLRHALAPGRGDVLQD 432
           L          H   PG+ + L+D
Sbjct: 202 LFCEVDGNFPNHHPDPGKPENLED 225



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>SYFB_METKA (Q8TX56) Phenylalanyl-tRNA synthetase beta chain (EC 6.1.1.20)|
           (Phenylalanine--tRNA ligase beta chain) (PheRS)
          Length = 590

 Score = 30.8 bits (68), Expect = 2.6
 Identities = 15/26 (57%), Positives = 19/26 (73%)
 Frame = -1

Query: 345 VKSFDEARMRENLDVDGWELTEEERR 268
           +KS  EA +RE LDV GWE+TE + R
Sbjct: 513 IKSVVEALLRE-LDVTGWEITERKHR 537



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>GATE_PYRFU (Q8U0W9) Glutamyl-tRNA(Gln) amidotransferase subunit E (EC 6.3.5.-)|
           (Glu-ADT subunit E)
          Length = 628

 Score = 30.8 bits (68), Expect = 2.6
 Identities = 19/53 (35%), Positives = 30/53 (56%), Gaps = 4/53 (7%)
 Frame = -1

Query: 330 EARMRENLDVDGWELTEEERRRI----AEIPQRKINLGKRYVSDHGPYKSLEE 184
           +ARM    D+    +TEE +RRI     E+PQ K+   ++YV + G  KS+ +
Sbjct: 425 KARMYPETDIPPIRITEEMKRRIKENLPELPQAKV---EKYVKEFGIDKSMAQ 474



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>HIS82_BURS3 (Q39CT7) Histidinol-phosphate aminotransferase 2 (EC 2.6.1.9)|
           (Imidazole acetol-phosphate transaminase 2)
          Length = 355

 Score = 30.8 bits (68), Expect = 2.6
 Identities = 22/57 (38%), Positives = 26/57 (45%)
 Frame = +1

Query: 226 LAEVDLALRDLGDPAALLLRELPAVHVQVLPHPGLVEALDDEAVPLLVHPPQAHLRH 396
           L E    LR   DP A  LRE  A H ++ P    V    DE   +L H  QA L+H
Sbjct: 50  LGETGDTLRRYPDPVARALRETVATHHRIKPEQVFVGNGSDE---VLAHTFQALLKH 103



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>GS69_BACSU (P80874) General stress protein 69 (EC 1.1.1.-) (GSP69) (AKR11B)|
          Length = 331

 Score = 30.8 bits (68), Expect = 2.6
 Identities = 18/68 (26%), Positives = 35/68 (51%), Gaps = 3/68 (4%)
 Frame = -1

Query: 429 LQDIAASR-GKSVAQVCLRWVYEQ--GDCLIVKSFDEARMRENLDVDGWELTEEERRRIA 259
           L  +A +R GKSV  + +RW+ +Q   D  +  +    ++    ++ GW L  E+++ I 
Sbjct: 248 LDKLAKTRYGKSVIHLAVRWILDQPGADIALWGARKPGQLEALSEITGWTLNSEDQKDIN 307

Query: 258 EIPQRKIN 235
            I +  I+
Sbjct: 308 TILENTIS 315



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>LNT_RHOPA (P61036) Apolipoprotein N-acyltransferase (EC 2.3.1.-) (ALP|
           N-acyltransferase)
          Length = 536

 Score = 30.8 bits (68), Expect = 2.6
 Identities = 18/43 (41%), Positives = 19/43 (44%)
 Frame = -3

Query: 184 ALGRRDMSSLWRPTGLPAYQRLSSSAMDGWLIGGQLCTDFPWN 56
           ALG      LWRP  L       S  +  WL  G L T FPWN
Sbjct: 121 ALGFALARLLWRPDSLRILSLAVSLTISEWL-RGHLLTGFPWN 162



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>GUAA_ANAMM (Q5P9L5) GMP synthase [glutamine-hydrolyzing] (EC 6.3.5.2)|
           (Glutamine amidotransferase) (GMP synthetase)
          Length = 529

 Score = 30.8 bits (68), Expect = 2.6
 Identities = 36/141 (25%), Positives = 63/141 (44%), Gaps = 1/141 (0%)
 Frame = +1

Query: 76  KAVPQSTSHPWPRMTNAGTPAGQSVSTGYSYLAVPELLE-GLVRPVVGHVALAEVDLALR 252
           K + Q T +P    +  G  +G  + + ++   +PE++   LV P+  H+   EV L  +
Sbjct: 327 KFLMQGTIYPDVIESGVGE-SGTKIKSHHNVGGLPEIMNLSLVEPL-RHLFKDEVRLLGK 384

Query: 253 DLGDPAALLLRELPAVHVQVLPHPGLVEALDDEAVPLLVHPPQAHLRHALAPGRGDVLQD 432
           +LG P+A+L R          P PGL   +  E     V   +  L   +     D+++D
Sbjct: 385 ELGLPSAILDR-------HPFPGPGLAVRIMGE-----VTAERVELLREIDNIYIDMMRD 432

Query: 433 AGVHHGVAAPVRALGPKRRVG 495
           +G++  +      L P R VG
Sbjct: 433 SGLYDHIWQAFAVLVPVRTVG 453



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>GNDS_HUMAN (Q12967) Ral guanine nucleotide dissociation stimulator (RalGEF)|
           (RalGDS)
          Length = 914

 Score = 30.4 bits (67), Expect = 3.4
 Identities = 41/167 (24%), Positives = 65/167 (38%), Gaps = 9/167 (5%)
 Frame = +1

Query: 19  SFTETQHIVLLIYSKGNQCKAVPQSTSHP--WPRMTNAGTPAGQSVSTGYSYLA--VPEL 186
           +FT TQ ++ L++ +  +C A+  S+ +    P     G P  Q  +   S L   + + 
Sbjct: 149 AFTTTQQVLDLLFKRYGRCDALTASSRYGCILPYSDEDGGPQDQLKNAISSILGTWLDQY 208

Query: 187 LEGLVRP-----VVGHVALAEVDLALRDLGDPAALLLRELPAVHVQVLPHPGLVEALDDE 351
            E   +P     +   VA  ++++   DL   A LLL +        L H   +EA  + 
Sbjct: 209 SEDFCQPPDFPCLKQLVAYVQLNMPGSDLERRAHLLLAQ--------LEHSEPIEAEPEA 260

Query: 352 AVPLLVHPPQAHLRHALAPGRGDVLQDAGVHHGVAAPVRALGPKRRV 492
             P+    P   L  AL P R      A       AP  A G +  V
Sbjct: 261 LSPVPALKPTPELELALTPARAPSPVPAPAPEPEPAPTPAPGSELEV 307



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>MURA1_BACSU (P70965) UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1 (EC|
           2.5.1.7) (Enoylpyruvate transferase 1)
           (UDP-N-acetylglucosamine enolpyruvyl transferase 1) (EPT
           1)
          Length = 436

 Score = 30.4 bits (67), Expect = 3.4
 Identities = 17/67 (25%), Positives = 35/67 (52%), Gaps = 1/67 (1%)
 Frame = +1

Query: 172 AVPELLEGLVRPVVGHVALAEVDLALRDLGDPAALL-LRELPAVHVQVLPHPGLVEALDD 348
           AVPE L  L+        + E+ + ++D G+   ++  +EL  + ++ +PHPG    +  
Sbjct: 256 AVPEHLTSLI------AKMEEMGVTIKDEGEGLRVIGPKELKPIDIKTMPHPGFPTDMQS 309

Query: 349 EAVPLLV 369
           + + LL+
Sbjct: 310 QMMALLL 316



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>THIC2_ARATH (Q9FIK7) Probable acetyl-CoA acetyltransferase, cytosolic 2 (EC|
           2.3.1.9) (Cytosolic acetoacetyl-CoA thiolase 2)
           (Thiolase 2)
          Length = 415

 Score = 30.4 bits (67), Expect = 3.4
 Identities = 26/100 (26%), Positives = 43/100 (43%), Gaps = 11/100 (11%)
 Frame = -1

Query: 492 YSPLGAKGTHWGSDAVMDAGV---LQDIAASRGKSVA-QVCL---RWVYEQGDCLIVKSF 334
           Y P   +G+  G D V+D  +   L D+    G  V  ++C    R   E+ D   ++SF
Sbjct: 135 YLPDARRGSRLGHDTVVDGMMKDGLWDVYNDFGMGVCGEICADQYRITREEQDAYAIQSF 194

Query: 333 DEARMRENLDVDGWELTEEE----RRRIAEIPQRKINLGK 226
           +     +N  +  WE+   E    R R + +  +   LGK
Sbjct: 195 ERGIAAQNTQLFAWEIVPVEVSTGRGRPSVVIDKDEGLGK 234



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>AK1A1_CRIGR (O70473) Alcohol dehydrogenase [NADP+] (EC 1.1.1.2) (Aldehyde|
           reductase) (Aldo-keto reductase family 1 member A1)
           (Fragment)
          Length = 228

 Score = 30.4 bits (67), Expect = 3.4
 Identities = 11/28 (39%), Positives = 18/28 (64%)
 Frame = -1

Query: 543 QRKLREFCRGKGIQLCAYSPLGAKGTHW 460
           Q +L   C+ +G+++ AYSPLG+    W
Sbjct: 178 QNELIAHCQARGLEVTAYSPLGSSDRAW 205



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>YEC4_EBV (P03235) Hypothetical protein EC-RF4|
          Length = 289

 Score = 30.0 bits (66), Expect = 4.4
 Identities = 14/40 (35%), Positives = 23/40 (57%), Gaps = 4/40 (10%)
 Frame = +1

Query: 349 EAVPLLVHPPQAHLRHALAPGRGDVLQDAGV----HHGVA 456
           +  P+LV  P+ H+ H +  G GD++  AG+    H+G A
Sbjct: 191 DPTPVLVLQPRGHVTHTVGMGEGDLVVVAGMVAVAHNGTA 230



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>MURA3_SYMTH (Q67J65) UDP-N-acetylglucosamine 1-carboxyvinyltransferase 3 (EC|
           2.5.1.7) (Enoylpyruvate transferase 3)
           (UDP-N-acetylglucosamine enolpyruvyl transferase 3) (EPT
           3)
          Length = 424

 Score = 30.0 bits (66), Expect = 4.4
 Identities = 16/48 (33%), Positives = 26/48 (54%), Gaps = 1/48 (2%)
 Frame = +1

Query: 226 LAEVDLALRDLGDPAALLLRELP-AVHVQVLPHPGLVEALDDEAVPLL 366
           L E  + + +LGD   ++ RE P A++V+ LP+PG       +   LL
Sbjct: 268 LREAGVEVHELGDAVRVVGRERPKAINVKTLPYPGFPTDAQSQMTALL 315



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>TREF1_MOUSE (Q8BXJ2) Transcriptional-regulating factor 1|
           (Transcriptional-regulating protein 132) (Zinc finger
           transcription factor TReP-132)
          Length = 1205

 Score = 29.6 bits (65), Expect = 5.8
 Identities = 12/25 (48%), Positives = 14/25 (56%)
 Frame = +1

Query: 316 PHPGLVEALDDEAVPLLVHPPQAHL 390
           PHPG    L   A+P+  H PQ HL
Sbjct: 208 PHPGFTGGLPKPALPVGQHAPQGHL 232



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>DUT_ASHGO (Q74ZF0) Deoxyuridine 5'-triphosphate nucleotidohydrolase (EC|
           3.6.1.23) (dUTPase) (dUTP pyrophosphatase)
          Length = 153

 Score = 29.3 bits (64), Expect = 7.6
 Identities = 13/38 (34%), Positives = 22/38 (57%)
 Frame = -1

Query: 426 QDIAASRGKSVAQVCLRWVYEQGDCLIVKSFDEARMRE 313
           +D A  RG  VAQ+ L  + +  + ++V+S DE+   E
Sbjct: 108 RDYAVKRGDRVAQLVLERIVDDAEVVVVESLDESSRGE 145



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>ATC1_YARLI (O43108) Calcium-transporting ATPase 1 (EC 3.6.3.8) (P-type calcium|
           ATPase)
          Length = 928

 Score = 29.3 bits (64), Expect = 7.6
 Identities = 18/73 (24%), Positives = 34/73 (46%)
 Frame = -1

Query: 468 THWGSDAVMDAGVLQDIAASRGKSVAQVCLRWVYEQGDCLIVKSFDEARMRENLDVDGWE 289
           +H  +D    A +   ++ +    V  +C    + +    +V +  +  + E LD  G E
Sbjct: 387 SHTEADPKAVAALKNSVSLANMLKVGNLCNNSKFNREAGHLVGNATDIALIEVLDYFGLE 446

Query: 288 LTEEERRRIAEIP 250
            T E R+R+AE+P
Sbjct: 447 DTRETRKRVAEVP 459



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>MOVP_CMVTR (Q83252) Movement protein (MP) (Protein 3A)|
          Length = 279

 Score = 29.3 bits (64), Expect = 7.6
 Identities = 22/61 (36%), Positives = 32/61 (52%)
 Frame = +1

Query: 82  VPQSTSHPWPRMTNAGTPAGQSVSTGYSYLAVPELLEGLVRPVVGHVALAEVDLALRDLG 261
           VPQ TS+       +G  AG+  S G  Y++VP++L  + R  V   A   + + L DLG
Sbjct: 59  VPQVTSNNLLSFFKSGYDAGELRSKG--YMSVPQVLCAVTR-TVSTDAEGSLKIYLADLG 115

Query: 262 D 264
           D
Sbjct: 116 D 116



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>MOVP_CMVS (Q66134) Movement protein (MP) (Protein 3A)|
          Length = 279

 Score = 29.3 bits (64), Expect = 7.6
 Identities = 22/61 (36%), Positives = 32/61 (52%)
 Frame = +1

Query: 82  VPQSTSHPWPRMTNAGTPAGQSVSTGYSYLAVPELLEGLVRPVVGHVALAEVDLALRDLG 261
           VPQ TS+       +G  AG+  S G  Y++VP++L  + R  V   A   + + L DLG
Sbjct: 59  VPQVTSNNLLSFFKSGYDAGELRSKG--YMSVPQVLCAVTR-TVSTDAEGSLKIYLADLG 115

Query: 262 D 264
           D
Sbjct: 116 D 116



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>MOVP_CMVKI (Q06938) Movement protein (MP) (Protein 3A)|
          Length = 279

 Score = 29.3 bits (64), Expect = 7.6
 Identities = 22/61 (36%), Positives = 32/61 (52%)
 Frame = +1

Query: 82  VPQSTSHPWPRMTNAGTPAGQSVSTGYSYLAVPELLEGLVRPVVGHVALAEVDLALRDLG 261
           VPQ TS+       +G  AG+  S G  Y++VP++L  + R  V   A   + + L DLG
Sbjct: 59  VPQVTSNNLLSFFKSGYDAGELRSKG--YMSVPQVLCAVTR-TVSTDAEGSLKIYLADLG 115

Query: 262 D 264
           D
Sbjct: 116 D 116



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>SWD3_YEAST (P38123) COMPASS component SWD3 (Complex proteins associated with|
           SET1 protein SWD3) (Set1C component SWD3)
          Length = 315

 Score = 29.3 bits (64), Expect = 7.6
 Identities = 20/67 (29%), Positives = 30/67 (44%), Gaps = 2/67 (2%)
 Frame = +1

Query: 31  TQHIVLLIYSKGNQCKAVPQSTSHPWPRMTNAGTPAGQSVSTGYSYLAVP--ELLEGLVR 204
           TQ + +LIY    +  +    TSH  P      +P GQ ++T     +V    L  GL+ 
Sbjct: 31  TQGLNILIYDINRRTVSQTLVTSHARPFSELCWSPDGQCIATASDDFSVEIIHLSYGLLH 90

Query: 205 PVVGHVA 225
             +GH A
Sbjct: 91  TFIGHTA 97



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>PCNB_ECOLI (P0ABF1) Poly(A) polymerase (EC 2.7.7.19) (PAP) (Plasmid copy|
           number protein)
          Length = 472

 Score = 28.9 bits (63), Expect = 9.9
 Identities = 17/56 (30%), Positives = 29/56 (51%), Gaps = 2/56 (3%)
 Frame = -3

Query: 244 QDQPRQALRVRPRALQVPRG--ALGRRDMSSLWRPTGLPAYQRLSSSAMDGWLIGG 83
           + +  QA+  RP+   +PR   A+ R+D+S       L    RL+ +  + WL+GG
Sbjct: 24  ESEAEQAV-ARPQVTVIPREQHAISRKDISE----NALKVMYRLNKAGYEAWLVGG 74



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>PCNB_ECOL6 (P0ABF2) Poly(A) polymerase (EC 2.7.7.19) (PAP) (Plasmid copy|
           number protein)
          Length = 472

 Score = 28.9 bits (63), Expect = 9.9
 Identities = 17/56 (30%), Positives = 29/56 (51%), Gaps = 2/56 (3%)
 Frame = -3

Query: 244 QDQPRQALRVRPRALQVPRG--ALGRRDMSSLWRPTGLPAYQRLSSSAMDGWLIGG 83
           + +  QA+  RP+   +PR   A+ R+D+S       L    RL+ +  + WL+GG
Sbjct: 24  ESEAEQAV-ARPQVTVIPREQHAISRKDISE----NALKVMYRLNKAGYEAWLVGG 74



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>PCNB_ECO57 (P0ABF3) Poly(A) polymerase (EC 2.7.7.19) (PAP) (Plasmid copy|
           number protein)
          Length = 472

 Score = 28.9 bits (63), Expect = 9.9
 Identities = 17/56 (30%), Positives = 29/56 (51%), Gaps = 2/56 (3%)
 Frame = -3

Query: 244 QDQPRQALRVRPRALQVPRG--ALGRRDMSSLWRPTGLPAYQRLSSSAMDGWLIGG 83
           + +  QA+  RP+   +PR   A+ R+D+S       L    RL+ +  + WL+GG
Sbjct: 24  ESEAEQAV-ARPQVTVIPREQHAISRKDISE----NALKVMYRLNKAGYEAWLVGG 74



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>ARLY_LISIN (Q929S8) Argininosuccinate lyase (EC 4.3.2.1) (Arginosuccinase)|
           (ASAL)
          Length = 456

 Score = 28.9 bits (63), Expect = 9.9
 Identities = 25/80 (31%), Positives = 35/80 (43%), Gaps = 2/80 (2%)
 Frame = +1

Query: 166 YLAVPELLEGLVRPVVG--HVALAEVDLALRDLGDPAALLLRELPAVHVQVLPHPGLVEA 339
           +L + +LL   + PV G  H A +  D    D+     L L+E  A  +Q L H   V  
Sbjct: 85  HLNIEKLLHEEIGPVAGKLHTARSRNDQVATDMH----LYLKEAVAEIIQSLKHLRAVLV 140

Query: 340 LDDEAVPLLVHPPQAHLRHA 399
              EA    + P   HL+HA
Sbjct: 141 QKAEANVETIMPGYTHLQHA 160



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>PPS1_BACSU (P39845) Peptide synthetase 1|
          Length = 2561

 Score = 28.9 bits (63), Expect = 9.9
 Identities = 25/88 (28%), Positives = 38/88 (43%)
 Frame = +1

Query: 28   ETQHIVLLIYSKGNQCKAVPQSTSHPWPRMTNAGTPAGQSVSTGYSYLAVPELLEGLVRP 207
            ET+    L+  + N+     Q+   P P +      A +S+      LAV +   G+  P
Sbjct: 1521 ETEISYRLLNERANRLARTLQNRKGPKPTVA---VLAKRSIDAIVGVLAVMKA-GGVYIP 1576

Query: 208  VVGHVALAEVDLALRDLGDPAALLLREL 291
            +  H   A ++  LRD G    LL REL
Sbjct: 1577 IDAHYPKARIEYILRDSGADILLLQREL 1604



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>YCCK_BACSU (P46905) Hypothetical oxidoreductase yccK (EC 1.-.-.-)|
          Length = 310

 Score = 28.9 bits (63), Expect = 9.9
 Identities = 28/121 (23%), Positives = 48/121 (39%), Gaps = 24/121 (19%)
 Frame = -1

Query: 543 QRKLREFCRGKGIQLCAYSPL--GAKGTHWGSDAVMD--------------------AGV 430
           +++L  +C  +GI    Y PL  G     +  D V D                       
Sbjct: 188 EKELLPYCEKQGISFIPYFPLASGLLTGKFTQDTVFDDFRKDKPQFQGETFIHNLKKVDK 247

Query: 429 LQDIAASRGKSVAQVCLRWVYEQG--DCLIVKSFDEARMRENLDVDGWELTEEERRRIAE 256
           L+ +A  +    A V L W+  +   D +I  +    ++++NL     ELTE+E   I++
Sbjct: 248 LKAVAEEKQADTAHVALAWLLTRPAIDAIIPGAKRPEQLQDNLKTLNIELTEDEVNFISD 307

Query: 255 I 253
           I
Sbjct: 308 I 308



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>Y2006_MYCTU (Q10850) Hypothetical glycosyl hydrolase Rv2006/MT2062 (EC 3.2.1.-)|
          Length = 1327

 Score = 28.9 bits (63), Expect = 9.9
 Identities = 17/59 (28%), Positives = 30/59 (50%)
 Frame = +3

Query: 21  IH*NATHRFIDLFQGKSVQSCPPINQPSMAEDDKRWYAGRPVGLHRLLISRRPRAPRGT 197
           +H  A  +F+D +  +  Q     + P   +D +R+ AG+P G+   L +R  R P G+
Sbjct: 38  VHAAAWTKFLDDYLTRRPQRTGEDHCPLTHDDYRRFLAGKPDGVADFLAARGIRLPPGS 96


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 75,401,697
Number of Sequences: 219361
Number of extensions: 1662130
Number of successful extensions: 6271
Number of sequences better than 10.0: 116
Number of HSP's better than 10.0 without gapping: 5984
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6227
length of database: 80,573,946
effective HSP length: 105
effective length of database: 57,541,041
effective search space used: 4373119116
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
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