>CYLD_HUMAN (Q9NQC7) Probable ubiquitin carboxyl-terminal hydrolase CYLD (EC|
           3.1.2.15) (Ubiquitin thioesterase CYLD)
           (Ubiquitin-specific-processing protease CYLD)
           (Deubiquitinating enzyme CYLD)
          Length = 956

 Score = 32.0 bits (71), Expect = 0.65
 Identities = 23/69 (33%), Positives = 35/69 (50%), Gaps = 3/69 (4%)
 Frame = -1

Query: 332 TPPEHHPFSAPSTPENCFVSMPTSLEPSPATSGSNHMCFNPFQAQSELQTMVSALVEAT- 156
           +PP   P     T EN F S+P SL   P T+GS         AQS ++ + +A V+ + 
Sbjct: 399 SPPLQPPPVNSLTTENRFHSLPFSLTKMPNTNGSIGHSPLSLSAQSVMEELNTAPVQESP 458

Query: 155 --SMPPADT 135
             +MPP ++
Sbjct: 459 PLAMPPGNS 467

>THA10_PONPY (Q5NVM3) THAP domain-containing protein 10|
          Length = 264

 Score = 32.0 bits (71), Expect = 0.65
 Identities = 23/85 (27%), Positives = 33/85 (38%), Gaps = 1/85 (1%)
 Frame = -1

Query: 293 PENCFVSMPTSLEPSPATSGSNHMCFNPFQAQSELQTMVSALVEATSMPPADTEEAGFAY 114
           P N   S+PT  E  P    +      P      +Q  V A  +        TEE     
Sbjct: 167 PSNTVTSVPTHCEEGPVHKSTQISLKRPRHRSVGIQAKVKAFGKRLCNATTQTEE----L 222

Query: 113 WSFDDSALDVNSFDEDV-TNFDISA 42
           WS   S  D+ S D ++ T++DI +
Sbjct: 223 WSRTSSLFDIYSSDSEIDTDWDIKS 247

>THA10_HUMAN (Q9P2Z0) THAP domain-containing protein 10|
          Length = 257

 Score = 30.8 bits (68), Expect = 1.5
 Identities = 23/85 (27%), Positives = 32/85 (37%), Gaps = 1/85 (1%)
 Frame = -1

Query: 293 PENCFVSMPTSLEPSPATSGSNHMCFNPFQAQSELQTMVSALVEATSMPPADTEEAGFAY 114
           P N   S+PT  E  P    +      P      +Q  V A  +        TEE     
Sbjct: 160 PSNTVTSVPTHCEEGPVHKSTQISLKRPRHRSVGIQAKVKAFGKRLCNATTQTEE----L 215

Query: 113 WSFDDSALDVNSFDEDV-TNFDISA 42
           WS   S  D+ S D +  T++DI +
Sbjct: 216 WSRTSSLFDIYSSDSETDTDWDIKS 240

>DYC1_CAEEL (Q8STF6) Dystrophin-like protein 1 (Dyb-1-binding and CAPON-related|
           protein)
          Length = 887

 Score = 30.8 bits (68), Expect = 1.5
 Identities = 22/68 (32%), Positives = 32/68 (47%), Gaps = 2/68 (2%)
 Frame = -1

Query: 341 SGMTPPEHHPFSAPSTPENCFVSMPTSLEPS-PATSGSNHMCFN-PFQAQSELQTMVSAL 168
           S   PP+H P   PST       MP S++ + P   G++ +  N P+Q Q        A 
Sbjct: 510 SSSQPPQHQPIYQPSTSTPLNPKMPLSIDHNDPRIPGNSSIRLNYPYQVQP------LAD 563

Query: 167 VEATSMPP 144
           + A S+PP
Sbjct: 564 LRAGSLPP 571

>PACN2_HUMAN (Q9UNF0) Protein kinase C and casein kinase substrate in neurons|
           protein 2
          Length = 486

 Score = 30.4 bits (67), Expect = 1.9
 Identities = 25/95 (26%), Positives = 42/95 (44%), Gaps = 11/95 (11%)
 Frame = -1

Query: 308 SAPSTPENCFVSMPTSLEPSPATSGSNHMCFNPFQAQSELQTMVS----------ALVEA 159
           S PS P     S   ++  +PA S  +   +NPF+ + +  + VS          +  E 
Sbjct: 336 SLPSKP-----SSTLNVPSNPAQSAQSQSSYNPFEDEDDTGSTVSEKDDTKAKNVSSYEK 390

Query: 158 TSMPPAD-TEEAGFAYWSFDDSALDVNSFDEDVTN 57
           T   P D +++     +S  D+  D N FD+D T+
Sbjct: 391 TQSYPTDWSDDESNNPFSSTDANGDSNPFDDDATS 425

>AMELX_BOVIN (P02817) Amelogenin, X isoform precursor (Class I amelogenin)|
          Length = 213

 Score = 30.4 bits (67), Expect = 1.9
 Identities = 16/52 (30%), Positives = 22/52 (42%)
 Frame = -1

Query: 335 MTPPEHHPFSAPSTPENCFVSMPTSLEPSPATSGSNHMCFNPFQAQSELQTM 180
           MTP +HH  + P   +  F   P S++P P      H    P Q    LQ +
Sbjct: 110 MTPTQHHQPNLPLPAQQPF--QPQSIQPQPHQPLQPHQPLQPMQPMQPLQPL 159

>TRZA_RHOCO (Q52725) S-triazine hydrolase (EC 3.8.1.-) (N-ethylammeline|
           chlorohydrolase)
          Length = 476

 Score = 30.4 bits (67), Expect = 1.9
 Identities = 25/77 (32%), Positives = 29/77 (37%), Gaps = 9/77 (11%)
 Frame = -1

Query: 347 AVSGMTPPEH-------HPFSAPSTPENCFVSMPTSLEPSPATSGSNHMCF--NPFQAQS 195
           A S  TP  H       HP +A S+      S+P SL     TS S H C    PF   S
Sbjct: 59  ASSTPTPTSHKSSSGVVHPMTATSSNGCTTCSIPASLPTQTTTSESEHCCTAPKPFVLAS 118

Query: 194 ELQTMVSALVEATSMPP 144
            L +        TS  P
Sbjct: 119 PLSSTTRTSDPTTSPAP 135

>PHSA_STRAT (Q53692) Phenoxazinone synthase (EC 1.-.-.-) (PHS)|
          Length = 642

 Score = 30.0 bits (66), Expect = 2.5
 Identities = 22/59 (37%), Positives = 29/59 (49%)
 Frame = -3

Query: 378 HHHALQFLLAGRERHDAAGAPPVLGAVDARELLRVDAHVPRTLAGDLGLEPHVFQPVPG 202
           H H   F + GR+ +DA+G    LG    R  +R+D   P  LA +      VFQ VPG
Sbjct: 527 HIHLADFQVLGRDAYDASGFDLALGG--TRTPVRLDPDTPVPLAPNELGHKDVFQ-VPG 582

>PHLB1_HUMAN (Q86UU1) Pleckstrin homology-like domain family B member 1 (Protein|
           LL5-alpha)
          Length = 1377

 Score = 30.0 bits (66), Expect = 2.5
 Identities = 16/52 (30%), Positives = 24/52 (46%), Gaps = 7/52 (13%)
 Frame = -1

Query: 332 TPPEHHPFSAPSTPENCFVSMPTSLEPS-------PATSGSNHMCFNPFQAQ 198
           T P   P S+P++  +C    P+  EP        PA S S H+   P Q++
Sbjct: 251 TSPAFSPLSSPASSGSCASHSPSGQEPGPSVPPLVPARSSSYHLALQPPQSR 302

>PHLB1_MOUSE (Q6PDH0) Pleckstrin homology-like domain family B member 1 (Protein|
           LL5-alpha)
          Length = 1371

 Score = 30.0 bits (66), Expect = 2.5
 Identities = 16/52 (30%), Positives = 24/52 (46%), Gaps = 7/52 (13%)
 Frame = -1

Query: 332 TPPEHHPFSAPSTPENCFVSMPTSLEPS-------PATSGSNHMCFNPFQAQ 198
           T P   P S+P++  +C    P+  EP        PA S S H+   P Q++
Sbjct: 251 TSPAFSPLSSPASSGSCASHSPSGQEPGPSVPPLVPARSSSYHLALQPPQSR 302

>LRP5_HUMAN (O75197) Low-density lipoprotein receptor-related protein 5 precursor|
          Length = 1615

 Score = 29.6 bits (65), Expect = 3.2
 Identities = 14/35 (40%), Positives = 18/35 (51%)
 Frame = -1

Query: 314  PFSAPSTPENCFVSMPTSLEPSPATSGSNHMCFNP 210
            P+  P TP + ++S   S  PSPAT  S    F P
Sbjct: 1572 PYPPPPTPHSQYLSAEDSCPPSPATERSYFHLFPP 1606

>PACN2_RAT (Q9QY17) Protein kinase C and casein kinase substrate in neurons 2|
           protein (Synaptic dynamin-associated protein II)
           (Syndapin 2) (Syndapin-II) (SdpII)
          Length = 488

 Score = 29.6 bits (65), Expect = 3.2
 Identities = 23/80 (28%), Positives = 37/80 (46%), Gaps = 11/80 (13%)
 Frame = -1

Query: 263 SLEPSPATSGSNHMCFNPFQAQSELQTMVS----------ALVEATSMPPAD-TEEAGFA 117
           S+  +PA S      +NPF+ + +  + VS          +  E T   PAD +++    
Sbjct: 348 SVPSNPAQSTQLQSSYNPFEDEDDTGSSVSEKEDIKAKNVSSYEKTQNYPADWSDDESNN 407

Query: 116 YWSFDDSALDVNSFDEDVTN 57
            +S  D+  D N FDED T+
Sbjct: 408 PFSSTDANGDSNPFDEDTTS 427

>PTPR2_MACNE (O02695) Receptor-type tyrosine-protein phosphatase N2 precursor|
           (EC 3.1.3.48) (R-PTP-N2) (M1851)
          Length = 1013

 Score = 29.3 bits (64), Expect = 4.2
 Identities = 21/71 (29%), Positives = 35/71 (49%)
 Frame = -3

Query: 393 NAGLEHHHALQFLLAGRERHDAAGAPPVLGAVDARELLRVDAHVPRTLAGDLGLEPHVFQ 214
           ++ +E HH +  L A   +   A  PP  G+++ + LLR  + +PR L     L P V Q
Sbjct: 232 DSSVERHHLMAALSAYAAQRPPA--PPGKGSLEPQYLLRAPSRMPRPL-----LSPAVPQ 284

Query: 213 PVPGAV*APDN 181
             P  +  P++
Sbjct: 285 KWPSPLGDPED 295

>TR240_HUMAN (Q9UHV7) Thyroid hormone receptor-associated protein complex 240|
           kDa component (Trap240) (Thyroid hormone
           receptor-associated protein 1) (Vitamin D3
           receptor-interacting protein complex component DRIP250)
           (DRIP 250) (Activator-recruited cofac
          Length = 2174

 Score = 29.3 bits (64), Expect = 4.2
 Identities = 19/55 (34%), Positives = 24/55 (43%), Gaps = 3/55 (5%)
 Frame = -1

Query: 284 CFVSMPTSLEPSPATSGSNH---MCFNPFQAQSELQTMVSALVEATSMPPADTEE 129
           CFV +P S  P+P+  GS H    C    Q  +   T   A+   T  PP   EE
Sbjct: 281 CFVLVPQSDIPTPSPVGSTHCSSSCLGVHQVPA--STRDPAMSSVTLTPPTSPEE 333

>FTS1_MOUSE (Q64362) Fused toes protein (FT1)|
          Length = 292

 Score = 28.9 bits (63), Expect = 5.5
 Identities = 16/59 (27%), Positives = 28/59 (47%), Gaps = 2/59 (3%)
 Frame = -1

Query: 332 TPPEHHPFSA-PSTPENCF-VSMPTSLEPSPATSGSNHMCFNPFQAQSELQTMVSALVE 162
           +PP   P    PS P+N   ++ PTS  P+  ++   H  + PF  +  L    + +V+
Sbjct: 30  SPPRSAPKKQLPSIPKNALPIAKPTSPAPAAQSTNGTHASYGPFYLEYSLLAEFTLVVK 88

>CBP_HUMAN (Q92793) CREB-binding protein (EC 2.3.1.48)|
          Length = 2442

 Score = 28.5 bits (62), Expect = 7.2
 Identities = 19/66 (28%), Positives = 29/66 (43%)
 Frame = -1

Query: 338  GMTPPEHHPFSAPSTPENCFVSMPTSLEPSPATSGSNHMCFNPFQAQSELQTMVSALVEA 159
            GMTPP+    + PSTP +     PT   P+P +  S     +    Q+  Q  V+   + 
Sbjct: 876  GMTPPQPAAPTQPSTPVSSSGQTPT---PTPGSVPSATQTQSTPTVQAAAQAQVTPQPQT 932

Query: 158  TSMPPA 141
               PP+
Sbjct: 933  PVQPPS 938

>FTS1_HUMAN (Q9H8T0) Fused toes protein homolog (Ft1)|
          Length = 292

 Score = 28.5 bits (62), Expect = 7.2
 Identities = 16/59 (27%), Positives = 28/59 (47%), Gaps = 2/59 (3%)
 Frame = -1

Query: 332 TPPEHHPFSA-PSTPENCF-VSMPTSLEPSPATSGSNHMCFNPFQAQSELQTMVSALVE 162
           +PP   P    PS P+N   ++ PTS  P+  ++   H  + PF  +  L    + +V+
Sbjct: 30  SPPRTAPKKQLPSIPKNALPITKPTSPAPAAQSTNGTHASYGPFYLEYSLLAEFTLVVK 88

>ULK1_MOUSE (O70405) Serine/threonine-protein kinase ULK1 (EC 2.7.11.1)|
           (Unc-51-like kinase 1) (Serine/threonine-protein kinase
           Unc51.1)
          Length = 1051

 Score = 28.5 bits (62), Expect = 7.2
 Identities = 26/85 (30%), Positives = 33/85 (38%)
 Frame = -1

Query: 320 HHPFSAPSTPENCFVSMPTSLEPSPATSGSNHMCFNPFQAQSELQTMVSALVEATSMPPA 141
           HHPF   STP      +P    PS + SGS+    +     S         ++ T   PA
Sbjct: 274 HHPFLDASTPIKKSPPVPVPSYPS-SGSGSSSSSSSASHLASPPSLGEMPQLQKTLTSPA 332

Query: 140 DTEEAGFAYWSFDDSALDVNSFDED 66
           D   AGF   S D      +S D D
Sbjct: 333 DA--AGFLQGSRDSGGSSKDSCDTD 355

>RRMJ_NATPD (Q3IT24) Ribosomal RNA large subunit methyltransferase J (EC|
           2.1.1.-) (rRNA (uridine-2'-O-)-methyltransferase) (23S
           rRNA m2U2552 methyltransferase)
          Length = 252

 Score = 28.5 bits (62), Expect = 7.2
 Identities = 18/60 (30%), Positives = 31/60 (51%)
 Frame = +1

Query: 238 EVAGEGSRDVGIDTKQFSGVDGAENGWCSGGVMPLTAGEEKLKGVVVLQPCVPAAMSPSV 417
           E+AGE    VG+D ++   ++G E      G M   A  EK++ +V     V + M+P++
Sbjct: 56  ELAGEAGTVVGVDLQRIDPIEGVET---VRGDMTEDATREKVRALVGEADVVISDMAPNM 112

>THS3_HALVO (Q9HHA2) Thermosome subunit 3 (Heat shock protein CCT3)|
          Length = 524

 Score = 28.1 bits (61), Expect = 9.4
 Identities = 18/54 (33%), Positives = 30/54 (55%), Gaps = 6/54 (11%)
 Frame = -3

Query: 369 ALQFLLAGRERHDAAGAPPVLGAVDARELLRVDAH------VPRTLAGDLGLEP 226
           A +  +A R R +AAG       ++ R+ L V+A+      +PRTLA + G++P
Sbjct: 411 ATEIAIADRIRSEAAG-------IEGRKQLAVEAYADAVEALPRTLAENTGMDP 457

>PACN2_MOUSE (Q9WVE8) Protein kinase C and casein kinase substrate in neurons|
           protein 2
          Length = 486

 Score = 28.1 bits (61), Expect = 9.4
 Identities = 21/80 (26%), Positives = 36/80 (45%), Gaps = 11/80 (13%)
 Frame = -1

Query: 263 SLEPSPATSGSNHMCFNPFQAQSELQTMVS----------ALVEATSMPPAD-TEEAGFA 117
           S+  +PA S      +NPF+ + +  + +S          +  E T   P D +++    
Sbjct: 346 SVPSNPAQSTQLQSSYNPFEDEDDTGSSISEKEDIKAKNVSSYEKTQTYPTDWSDDESNN 405

Query: 116 YWSFDDSALDVNSFDEDVTN 57
            +S  D+  D N FDED T+
Sbjct: 406 PFSSTDANGDSNPFDEDTTS 425

>HHP1_SCHPO (P40235) Casein kinase I homolog hhp1 (EC 2.7.11.1)|
          Length = 365

 Score = 28.1 bits (61), Expect = 9.4
 Identities = 13/43 (30%), Positives = 23/43 (53%)
 Frame = -1

Query: 206 QAQSELQTMVSALVEATSMPPADTEEAGFAYWSFDDSALDVNS 78
           Q Q +LQ  +SA  +A + PP  +    +   +FD+   D+N+
Sbjct: 303 QHQQQLQQQLSATPQAINPPPERSSFRNYQKQNFDEKGGDINT 345

>SPE1_SOYBN (Q39827) Arginine decarboxylase (EC 4.1.1.19) (ARGDC) (ADC)|
          Length = 692

 Score = 28.1 bits (61), Expect = 9.4
 Identities = 16/42 (38%), Positives = 18/42 (42%)
 Frame = -3

Query: 396 GNAGLEHHHALQFLLAGRERHDAAGAPPVLGAVDARELLRVD 271
           G A + HH  L F   G    +  GAPP L A    E L  D
Sbjct: 392 GRAIVSHHSVLIFEAVGTSSTNGGGAPPALSAHYLAEELSED 433

>PTPR2_HUMAN (Q92932) Receptor-type tyrosine-protein phosphatase N2 precursor|
           (EC 3.1.3.48) (R-PTP-N2) (Islet cell autoantigen-related
           protein) (ICAAR) (IAR) (Phogrin)
          Length = 1015

 Score = 28.1 bits (61), Expect = 9.4
 Identities = 15/48 (31%), Positives = 27/48 (56%)
 Frame = -3

Query: 393 NAGLEHHHALQFLLAGRERHDAAGAPPVLGAVDARELLRVDAHVPRTL 250
           ++G++ HH +  L A   +   A  PP  G+++ + LLR  + +PR L
Sbjct: 234 DSGVDRHHLMAALSAYAAQRPPA--PPGEGSLEPQYLLRAPSRMPRPL 279

>PSA73_DROVI (O16812) Proteasome subunit alpha type 7-1B (EC 3.4.25.1)|
           (Testis-specific proteasome 28 kDa subunit 1B)
          Length = 245

 Score = 28.1 bits (61), Expect = 9.4
 Identities = 14/31 (45%), Positives = 18/31 (58%)
 Frame = -1

Query: 203 AQSELQTMVSALVEATSMPPADTEEAGFAYW 111
           A S ++ +V AL  ATS+ PA  E A   YW
Sbjct: 184 AASAMKHVVRALFTATSLDPASIELAVLRYW 214

>HXB3A_BRARE (O42368) Homeobox protein Hox-B3a (Hox-B3)|
          Length = 417

 Score = 28.1 bits (61), Expect = 9.4
 Identities = 13/32 (40%), Positives = 15/32 (46%)
 Frame = -1

Query: 329 PPEHHPFSAPSTPENCFVSMPTSLEPSPATSG 234
           PPEHHP    S P+N      T+    P  SG
Sbjct: 79  PPEHHPPPQVSPPQNTVNVAATNATQQPGGSG 110

>CEBPB_HUMAN (P17676) CCAAT/enhancer-binding protein beta (C/EBP beta) (Nuclear|
           factor NF-IL6) (Transcription factor 5)
          Length = 345

 Score = 28.1 bits (61), Expect = 9.4
 Identities = 11/27 (40%), Positives = 18/27 (66%)
 Frame = -1

Query: 305 APSTPENCFVSMPTSLEPSPATSGSNH 225
           AP+T  + F + P +  P+PA+SG +H
Sbjct: 89  APATATDTFEAAPPAPAPAPASSGQHH 115

>CEBPB_BOVIN (O02755) CCAAT/enhancer-binding protein beta (C/EBP beta)|
          Length = 348

 Score = 28.1 bits (61), Expect = 9.4
 Identities = 11/27 (40%), Positives = 18/27 (66%)
 Frame = -1

Query: 305 APSTPENCFVSMPTSLEPSPATSGSNH 225
           AP+T  + F + P++  P PA+SG +H
Sbjct: 89  APTTASDTFEAAPSAPAPVPASSGQHH 115


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 42,298,726
Number of Sequences: 219361
Number of extensions: 813243
Number of successful extensions: 3531
Number of sequences better than 10.0: 28
Number of HSP's better than 10.0 without gapping: 3403
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3531
length of database: 80,573,946
effective HSP length: 101
effective length of database: 58,418,485
effective search space used: 2453576370
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)