ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
menu 
| Clone Name | rbart34g12 |
|---|---|
| Clone Library Name | barley_pub |
>C86A2_ARATH (O23066) Cytochrome P450 86A2 (EC 1.14.-.-)| Length = 553 Score = 89.0 bits (219), Expect = 6e-18 Identities = 45/95 (47%), Positives = 62/95 (65%), Gaps = 1/95 (1%) Frame = -3 Query: 460 WGKDCAEFKPERWLG-ENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEF 284 WG+DC EFKPERW+ ++G F +R+ F+AGPR CLGK++AY+QMK+IAA+VL Sbjct: 421 WGEDCLEFKPERWISPDDGKFVNHDQYRFVAFNAGPRICLGKDLAYLQMKTIAAAVLLRH 480 Query: 283 TVDVVRKNAGSSAPEHVLSVTLRMKGGLPVQIRRR 179 + V A E +S+TL MK GL V + +R Sbjct: 481 RLTV----APGHKVEQKMSLTLFMKNGLLVNVHKR 511
>C86A1_ARATH (P48422) Cytochrome P450 86A1 (EC 1.14.-.-) (CYPLXXXVI)| (P450-dependent fatty acid omega-hydroxylase) Length = 513 Score = 86.7 bits (213), Expect = 3e-17 Identities = 46/99 (46%), Positives = 64/99 (64%), Gaps = 2/99 (2%) Frame = -3 Query: 463 IWGKDCAEFKPERWLGENGAF--RPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLE 290 IWG+DC EF+PERWL +G P+ +++ F+AGPRTCLGK++AY QMKS+A++VL Sbjct: 416 IWGEDCLEFRPERWLTADGERFETPKDGYKFVAFNAGPRTCLGKDLAYNQMKSVASAVLL 475 Query: 289 EFTVDVVRKNAGSSAPEHVLSVTLRMKGGLPVQIRRRVE 173 + V V E +S+TL MK GL V ++ R E Sbjct: 476 RYRVFPV----PGHRVEQKMSLTLFMKNGLRVYLQPRGE 510
>C94A2_VICSA (P98188) Cytochrome P450 94A2 (EC 1.14.-.-) (P450-dependent fatty| acid omega-hydroxylase) Length = 513 Score = 82.8 bits (203), Expect = 4e-16 Identities = 44/99 (44%), Positives = 57/99 (57%), Gaps = 4/99 (4%) Frame = -3 Query: 463 IWGKDCAEFKPERWLGENG----AFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASV 296 IWG D AEF+PERWL + +F + Y VF AGPR C+GKEMA++QMK + A + Sbjct: 413 IWGPDWAEFRPERWLSRDEVGKWSFVGIDYYSYPVFQAGPRVCIGKEMAFLQMKRVVAGI 472 Query: 295 LEEFTVDVVRKNAGSSAPEHVLSVTLRMKGGLPVQIRRR 179 + F VV PE+ T MKGG PV+I +R Sbjct: 473 MGRFR--VVPAMVEGIEPEYTAHFTSVMKGGFPVKIEKR 509
>C94A1_VICSA (O81117) Cytochrome P450 94A1 (EC 1.14.-.-) (P450-dependent fatty| acid omega-hydroxylase) Length = 514 Score = 80.9 bits (198), Expect = 2e-15 Identities = 44/101 (43%), Positives = 63/101 (62%), Gaps = 5/101 (4%) Frame = -3 Query: 466 AIWGKDCAEFKPERWLGE---NG--AFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAA 302 ++WG D AEF+PERWL + NG F + Y VF AGPR CLGKEMA++QMK I A Sbjct: 414 SLWGDDWAEFRPERWLEKDEVNGKWVFVGRDSYSYPVFQAGPRVCLGKEMAFMQMKRIVA 473 Query: 301 SVLEEFTVDVVRKNAGSSAPEHVLSVTLRMKGGLPVQIRRR 179 ++ +F VV + + P + ++ +M+GG PV I++R Sbjct: 474 GIVGKF--KVVPEAHLAQEPGFISFLSSQMEGGFPVTIQKR 512
>CP4V3_MOUSE (Q9DBW0) Cytochrome P450 4V3 (EC 1.14.-.-)| Length = 525 Score = 56.6 bits (135), Expect = 3e-08 Identities = 32/93 (34%), Positives = 52/93 (55%) Frame = -3 Query: 451 DCAEFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTVDV 272 D EF+PER+ EN R P+ Y F AGPR C+G++ A ++ K+I A +L +F V+ Sbjct: 435 DPEEFRPERFFPENSQGR--HPYAYVPFSAGPRNCIGQKFAVMEEKTILACILRQFWVES 492 Query: 271 VRKNAGSSAPEHVLSVTLRMKGGLPVQIRRRVE 173 +K ++ LR G+ ++++RR E Sbjct: 493 NQKREELGLAGDLI---LRPNNGIWIKLKRRHE 522
>C13AA_CAEEL (Q09653) Putative cytochrome P450 CYP13A10 (EC 1.14.-.-)| Length = 519 Score = 56.6 bits (135), Expect = 3e-08 Identities = 29/70 (41%), Positives = 40/70 (57%), Gaps = 3/70 (4%) Frame = -3 Query: 463 IWGKDCAEFKPERWLGENGAFRPESPFR---YTVFHAGPRTCLGKEMAYVQMKSIAASVL 293 IWG D EFKPERWL N + F+ Y F GPR C+G +AY++ K + A +L Sbjct: 428 IWGDDAKEFKPERWLDPNC----DQVFQKGGYISFGLGPRQCVGMRLAYMEEKMLLAHIL 483 Query: 292 EEFTVDVVRK 263 ++T +V K Sbjct: 484 RKYTFEVGTK 493
>CP4D1_DROSI (O16805) Cytochrome P450 4d1 (EC 1.14.-.-) (CYPIVD1)| Length = 512 Score = 55.5 bits (132), Expect = 7e-08 Identities = 33/88 (37%), Positives = 50/88 (56%) Frame = -3 Query: 439 FKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTVDVVRKN 260 FKPER+ A + +P+ Y F AGPR C+G++ A +++K+I A+VL + VD V Sbjct: 427 FKPERFDVVTTAEKL-NPYAYIPFSAGPRNCIGQKFAMLEIKAIVANVLRHYEVDFV--G 483 Query: 259 AGSSAPEHVLSVTLRMKGGLPVQIRRRV 176 S P + + LR K L ++R RV Sbjct: 484 DSSEPPVLIAELILRTKDPLMFKVRERV 511
>C13A6_CAEEL (Q27515) Putative cytochrome P450 CYP13A6 (EC 1.14.-.-)| Length = 518 Score = 55.5 bits (132), Expect = 7e-08 Identities = 27/62 (43%), Positives = 39/62 (62%), Gaps = 1/62 (1%) Frame = -3 Query: 463 IWGKDCAEFKPERWLGENGAFRP-ESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEE 287 IWG+D +FKPERW ENGA E Y F +GPR C+G +A ++ K + A +L+E Sbjct: 426 IWGEDVEDFKPERW--ENGACEHLEHNGSYIPFGSGPRQCIGMRLAQMEQKILLAQILKE 483 Query: 286 FT 281 ++ Sbjct: 484 YS 485
>CP4D1_DROME (P33269) Cytochrome P450 4d1 (EC 1.14.-.-) (CYPIVD1)| Length = 512 Score = 55.1 bits (131), Expect = 9e-08 Identities = 33/88 (37%), Positives = 50/88 (56%) Frame = -3 Query: 439 FKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTVDVVRKN 260 FKPER+ A + +P+ Y F AGPR C+G++ A +++K+I A+VL + VD V Sbjct: 427 FKPERFDVVTTAEKL-NPYAYIPFSAGPRNCIGQKFAMLEIKAIVANVLRHYEVDFV--G 483 Query: 259 AGSSAPEHVLSVTLRMKGGLPVQIRRRV 176 S P + + LR K L ++R RV Sbjct: 484 DSSEPPVLIAELILRTKEPLMFKVRERV 511
>C13A8_CAEEL (Q27516) Putative cytochrome P450 CYP13A8 (EC 1.14.-.-)| Length = 509 Score = 53.9 bits (128), Expect = 2e-07 Identities = 30/96 (31%), Positives = 48/96 (50%) Frame = -3 Query: 463 IWGKDCAEFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEF 284 +WG D EFKPERW + P+ Y F AGPR CLG A ++ K + + +L+++ Sbjct: 422 VWGNDVEEFKPERW---DSPLTPQQA--YLSFGAGPRVCLGMRFALLEQKGLLSHILKKY 476 Query: 283 TVDVVRKNAGSSAPEHVLSVTLRMKGGLPVQIRRRV 176 T + NA + P ++ L + ++ RV Sbjct: 477 TFET---NAKTQLPIKLVGRATARPENLFLSLKPRV 509
>C13A3_CAEEL (Q27517) Putative cytochrome P450 CYP13A3 (EC 1.14.-.-)| Length = 520 Score = 53.9 bits (128), Expect = 2e-07 Identities = 23/62 (37%), Positives = 40/62 (64%) Frame = -3 Query: 460 WGKDCAEFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFT 281 WG++ EFKPERW E+G + + Y F GPR C+G +AY++ K + A +L++++ Sbjct: 429 WGENANEFKPERW--ESGDEQAVAKGAYLPFGLGPRICIGMRLAYMEEKMLLAQILKKYS 486 Query: 280 VD 275 ++ Sbjct: 487 LE 488
>CP4C3_DROME (Q9VA27) Cytochrome P450 4c3 (EC 1.14.-.-) (CYPIVC3)| Length = 535 Score = 53.1 bits (126), Expect = 3e-07 Identities = 30/88 (34%), Positives = 51/88 (57%) Frame = -3 Query: 442 EFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTVDVVRK 263 +F P+ +L EN A R PF Y F AGPR C+G++ A ++ K++ ++VL ++ ++ V + Sbjct: 452 QFNPDNFLPENCAGR--HPFAYIPFSAGPRNCIGQKFAILEEKAVISTVLRKYKIEAVDR 509 Query: 262 NAGSSAPEHVLSVTLRMKGGLPVQIRRR 179 + ++ LR K GL V+I R Sbjct: 510 REDLTLLGELI---LRPKDGLRVKITPR 534
>C4D10_DROMT (O18596) Cytochrome P450 4d10 (EC 1.14.-.-) (CYPIVD10)| Length = 513 Score = 52.8 bits (125), Expect = 4e-07 Identities = 30/88 (34%), Positives = 51/88 (57%) Frame = -3 Query: 439 FKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTVDVVRKN 260 FKPER+ A + +P Y F AGPR C+G++ A +++K+IAA+VL + ++ V Sbjct: 428 FKPERFDVVTSAEKL-NPHAYIPFSAGPRNCIGQKFAMLEIKAIAANVLRHYEIEFV--G 484 Query: 259 AGSSAPEHVLSVTLRMKGGLPVQIRRRV 176 +P + + LR K L ++++RV Sbjct: 485 NAEESPVLIAELILRTKDPLMFKLKKRV 512
>CP4V2_PONPY (Q5RCN6) Cytochrome P450 4V2 (EC 1.14.-.-)| Length = 525 Score = 52.8 bits (125), Expect = 4e-07 Identities = 28/88 (31%), Positives = 49/88 (55%) Frame = -3 Query: 442 EFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTVDVVRK 263 EF+PER+ EN R P+ Y F AGPR C+G++ A ++ K+I + +L F ++ +K Sbjct: 438 EFQPERFFPENAQGR--HPYAYVPFSAGPRNCIGQKFAVMEEKTILSCILRHFWIESNQK 495 Query: 262 NAGSSAPEHVLSVTLRMKGGLPVQIRRR 179 ++ LR G+ ++++RR Sbjct: 496 REELGLEGQLI---LRPSNGIWIKLKRR 520
>CP4V2_HUMAN (Q6ZWL3) Cytochrome P450 4V2 (EC 1.14.-.-)| Length = 525 Score = 52.8 bits (125), Expect = 4e-07 Identities = 28/88 (31%), Positives = 49/88 (55%) Frame = -3 Query: 442 EFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTVDVVRK 263 EF+PER+ EN R P+ Y F AGPR C+G++ A ++ K+I + +L F ++ +K Sbjct: 438 EFQPERFFPENAQGR--HPYAYVPFSAGPRNCIGQKFAVMEEKTILSCILRHFWIESNQK 495 Query: 262 NAGSSAPEHVLSVTLRMKGGLPVQIRRR 179 ++ LR G+ ++++RR Sbjct: 496 REELGLEGQLI---LRPSNGIWIKLKRR 520
>C4AA1_DROME (Q9V7G5) Probable cytochrome P450 4aa1 (EC 1.14.-.-) (CYPIVAA1)| Length = 514 Score = 52.4 bits (124), Expect = 6e-07 Identities = 30/91 (32%), Positives = 49/91 (53%) Frame = -3 Query: 451 DCAEFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTVDV 272 D +F+PER+ EN R P+ + F AGPR C+G A +++K+I + +L + + Sbjct: 422 DPEKFQPERFSPENSENR--HPYAFLPFSAGPRYCIGNRFAIMEIKTIVSRLLRSYQLLP 479 Query: 271 VRKNAGSSAPEHVLSVTLRMKGGLPVQIRRR 179 V G + +TLR GGL V+++ R Sbjct: 480 V---TGKTTIAATFRITLRASGGLWVRLKER 507
>CP311_DROME (Q9VYQ7) Probable cytochrome P450 311a1 (EC 1.14.-.-) (CYPCCCXIA1)| Length = 483 Score = 52.4 bits (124), Expect = 6e-07 Identities = 24/61 (39%), Positives = 37/61 (60%) Frame = -3 Query: 439 FKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTVDVVRKN 260 FKPERWL E+GA P + F Y F GP C+G+ + + MK + A ++ EF +++ + Sbjct: 401 FKPERWLPEDGAVAPPA-FSYIPFSGGPHVCIGRRYSLLLMKLLTARLVREFQMELSPEQ 459 Query: 259 A 257 A Sbjct: 460 A 460
>C13A7_CAEEL (Q27519) Putative cytochrome P450 CYP13A7 (EC 1.14.-.-)| Length = 518 Score = 52.4 bits (124), Expect = 6e-07 Identities = 27/82 (32%), Positives = 43/82 (52%) Frame = -3 Query: 463 IWGKDCAEFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEF 284 +WG D EFKPERW + F + Y F GPR C+G +A ++MK + ++L+ + Sbjct: 428 VWGDDVNEFKPERWESGDELFFAKGG--YLPFGMGPRICIGMRLAMMEMKMLLTNILKNY 485 Query: 283 TVDVVRKNAGSSAPEHVLSVTL 218 T + + PE V+ + L Sbjct: 486 TFE--------TTPETVIPLKL 499
>CP52B_CANTR (P30607) Cytochrome P450 52A2 (EC 1.14.14.-) (CYPLIIA2)| (Alkane-inducible P450-ALK2) Length = 522 Score = 51.6 bits (122), Expect = 1e-06 Identities = 29/95 (30%), Positives = 51/95 (53%), Gaps = 3/95 (3%) Frame = -3 Query: 463 IWGKDCAEFKPERWLGENGAFRPESP---FRYTVFHAGPRTCLGKEMAYVQMKSIAASVL 293 I+G+D EF+PERW F PE+ + + F+ GPR CLG++ A + + +L Sbjct: 434 IYGEDALEFRPERW------FEPETKKLGWAFLPFNGGPRICLGQQFALTEASYVTVRLL 487 Query: 292 EEFTVDVVRKNAGSSAPEHVLSVTLRMKGGLPVQI 188 +EF+ + N S P+ + +T+ + G +Q+ Sbjct: 488 QEFSHLTMDPNTEYS-PKKMSHLTMSLFDGANIQM 521
>C13A1_CAEEL (Q27520) Putative cytochrome P450 CYP13A1 (EC 1.14.-.-)| Length = 519 Score = 51.6 bits (122), Expect = 1e-06 Identities = 25/67 (37%), Positives = 35/67 (52%) Frame = -3 Query: 463 IWGKDCAEFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEF 284 IWG D +FKPERW N + Y F GPR C+G +AY++ K + +L +F Sbjct: 428 IWGDDAEDFKPERWQTPNSD-QIYQKSGYIPFGLGPRQCIGMRLAYMEEKILLVHILRKF 486 Query: 283 TVDVVRK 263 T + K Sbjct: 487 TFETGAK 493
>C4AE1_DROME (O46054) Cytochrome P450 4ae1 (EC 1.14.-.-) (CYPIVAE1)| Length = 496 Score = 51.6 bits (122), Expect = 1e-06 Identities = 29/88 (32%), Positives = 48/88 (54%) Frame = -3 Query: 439 FKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTVDVVRKN 260 F+PER LGE SP+ Y F AGPR C+G++ A ++MK++ V+ + + + + Sbjct: 415 FQPERHLGEEAPRL--SPYSYIPFSAGPRNCIGQKFALLEMKTMVTKVIRHYQLLPMGAD 472 Query: 259 AGSSAPEHVLSVTLRMKGGLPVQIRRRV 176 E + + LR K G+ V +R R+ Sbjct: 473 V-----EPSIKIVLRSKSGVNVGLRPRL 495
>C13A4_CAEEL (Q27513) Putative cytochrome P450 CYP13A4 (EC 1.14.-.-)| Length = 520 Score = 51.2 bits (121), Expect = 1e-06 Identities = 23/63 (36%), Positives = 36/63 (57%) Frame = -3 Query: 463 IWGKDCAEFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEF 284 +WG D +EFKPERW + F + Y F GPR C+G +A ++ K + +L+++ Sbjct: 428 VWGDDASEFKPERWETGDELFYAKGG--YLPFGMGPRICIGMRLAMMEEKLLLTHILKKY 485 Query: 283 TVD 275 T D Sbjct: 486 TFD 488
>CP4C1_BLADI (P29981) Cytochrome P450 4C1 (EC 1.14.14.1) (CYPIVC1)| Length = 511 Score = 50.1 bits (118), Expect = 3e-06 Identities = 28/90 (31%), Positives = 49/90 (54%) Frame = -3 Query: 439 FKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTVDVVRKN 260 F P+ +L E A R P+ Y F AGPR C+G++ A ++ K++ +S+L F V + K Sbjct: 424 FNPDNFLPERVAKR--HPYAYVPFSAGPRNCIGQKFATLEEKTVLSSILRNFKVRSIEKR 481 Query: 259 AGSSAPEHVLSVTLRMKGGLPVQIRRRVEA 170 + ++ LR + G+ V++ R+ A Sbjct: 482 EDLTLMNELI---LRPESGIKVELIPRLPA 508
>C13A5_CAEEL (Q27514) Putative cytochrome P450 CYP13A5 (EC 1.14.-.-)| Length = 520 Score = 49.7 bits (117), Expect = 4e-06 Identities = 21/63 (33%), Positives = 36/63 (57%) Frame = -3 Query: 463 IWGKDCAEFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEF 284 +WG+D EF+PERW + F + Y F GPR C+G +A ++ K + +L+++ Sbjct: 428 VWGEDANEFRPERWESGDELFYAKGG--YLPFGMGPRICIGMRLAMMEKKMLLTHILKKY 485 Query: 283 TVD 275 T + Sbjct: 486 TFE 488
>CP4E3_DROME (Q9VL92) Cytochrome P450 4e3 (EC 1.14.-.-) (CYPIVE3)| Length = 526 Score = 49.7 bits (117), Expect = 4e-06 Identities = 33/117 (28%), Positives = 56/117 (47%), Gaps = 25/117 (21%) Frame = -3 Query: 454 KDCAEFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTV- 278 KD F+PER+ E A PF Y F AGPR C+G++ A +++K++ + V+ F V Sbjct: 413 KDPHHFRPERFEEEKPA-----PFEYLPFSAGPRNCIGQKFALLELKTVISKVVRSFEVL 467 Query: 277 ----------------------DVVRKNAGSSAPEHVLS--VTLRMKGGLPVQIRRR 179 + +++ AG + +LS +TL+ GL +++R R Sbjct: 468 PAVDELVSTDGRLNTYLGLAPDEKLKREAGRHKYDPILSAVLTLKSDNGLHLRLRER 524
>C13A2_CAEEL (Q27518) Putative cytochrome P450 CYP13A2 (EC 1.14.-.-)| Length = 515 Score = 49.7 bits (117), Expect = 4e-06 Identities = 25/72 (34%), Positives = 37/72 (51%), Gaps = 5/72 (6%) Frame = -3 Query: 463 IWGKDCAEFKPERW-----LGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAAS 299 +WG+D EFKPERW L GA+ P F GPR C+G +A ++ K + Sbjct: 425 LWGEDVKEFKPERWSTDEPLEHKGAYLP--------FGLGPRQCIGMRLAIMEQKILLTH 476 Query: 298 VLEEFTVDVVRK 263 +L+ +T + K Sbjct: 477 LLKNYTFETGNK 488
>CP3AR_ONCMY (O42563) Cytochrome P450 3A27 (EC 1.14.14.1) (CYPIIIA27)| Length = 518 Score = 48.9 bits (115), Expect = 6e-06 Identities = 31/97 (31%), Positives = 43/97 (44%), Gaps = 8/97 (8%) Frame = -3 Query: 463 IWGKDCAEFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEF 284 IW D EFKPER+ EN P+ Y F AGPR C+G A + +K +L+ F Sbjct: 412 IWS-DPEEFKPERFSKENK--ESIDPYTYMPFGAGPRNCIGMRFALIMIKLAMVEILQSF 468 Query: 283 TVDVVRK--------NAGSSAPEHVLSVTLRMKGGLP 197 T V + N G P+ + + L + P Sbjct: 469 TFSVCDETEIPLEMDNQGLLMPKRPIKLRLEARRNTP 505
>CP52D_CANMA (P16141) Cytochrome P450 52A4 (EC 1.14.14.-) (CYPLIIA4)| (Alkane-inducible P450-ALK3-A) (P450-CM2) Length = 537 Score = 48.5 bits (114), Expect = 8e-06 Identities = 29/97 (29%), Positives = 52/97 (53%), Gaps = 4/97 (4%) Frame = -3 Query: 466 AIWGKDCAEFKPERWLGENGAFRPESP---FRYTVFHAGPRTCLGKEMAYVQMKSIAASV 296 +I+G+D F+PERW F PE+ + Y F+ GPR CLG++ A + + + Sbjct: 448 SIYGEDANVFRPERW------FEPETRKLGWAYVPFNGGPRICLGQQFALTEASYVTVRL 501 Query: 295 LEEFTVDVVRKNAGSSAPEHVL-SVTLRMKGGLPVQI 188 L+EF + ++A + P + S+T+ + G +Q+ Sbjct: 502 LQEF--HTLTQDANTRYPPRLQNSLTVSLCDGANIQM 536
>CP53_ASPNG (P17549) Benzoate 4-monooxygenase (EC 1.14.13.12)| (Benzoate-para-hydroxylase) (Cytochrome P450 53) (BpH) Length = 517 Score = 48.5 bits (114), Expect = 8e-06 Identities = 28/95 (29%), Positives = 44/95 (46%) Frame = -3 Query: 463 IWGKDCAEFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEF 284 IWG D +F PERW + P + F GPR C+G+ +A +++ I +V F Sbjct: 425 IWGPDAEQFVPERW--DPARLTPRQKAAFIPFSTGPRACVGRNVAEMELLVICGTVFRLF 482 Query: 283 TVDVVRKNAGSSAPEHVLSVTLRMKGGLPVQIRRR 179 ++ ++ P LR GL V ++RR Sbjct: 483 EFEMQQE-----GPMETREGFLRKPLGLQVGMKRR 512
>CP4P2_DROME (Q9V557) Probable cytochrome P450 4p2 (EC 1.14.-.-) (CYPIVP2)| Length = 520 Score = 48.5 bits (114), Expect = 8e-06 Identities = 29/88 (32%), Positives = 48/88 (54%) Frame = -3 Query: 442 EFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTVDVVRK 263 EF+PER+L +N R P+ Y F AG R C+G++ A +MK++ +L+ F + V Sbjct: 435 EFRPERFLPQNCLKR--HPYAYIPFSAGQRNCIGQKYAMQEMKTLMVVILKHFKILPV-- 490 Query: 262 NAGSSAPEHVLSVTLRMKGGLPVQIRRR 179 + + +TLR K + V++ RR Sbjct: 491 -IDPKSIVFQVGITLRFKNKIKVKLVRR 517
>CP4D2_DROME (Q27589) Cytochrome P450 4d2 (EC 1.14.-.-) (CYPIVD2)| Length = 501 Score = 48.1 bits (113), Expect = 1e-05 Identities = 26/88 (29%), Positives = 46/88 (52%) Frame = -3 Query: 442 EFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTVDVVRK 263 EF+PER+ + P + Y F AGPR C+G++ A ++MKS + +L F + + Sbjct: 421 EFRPERFDADVPQIHP---YAYIPFSAGPRNCIGQKFAMLEMKSTVSKLLRHFELLPL-- 475 Query: 262 NAGSSAPEHVLSVTLRMKGGLPVQIRRR 179 P H +++ LR G+ + ++ R Sbjct: 476 ---GPEPRHSMNIVLRSANGVHLGLKPR 500
>CP4D8_DROME (Q9VS79) Cytochrome P450 4d8 (EC 1.14.-.-) (CYPIVD8)| Length = 463 Score = 47.8 bits (112), Expect = 1e-05 Identities = 28/88 (31%), Positives = 51/88 (57%) Frame = -3 Query: 442 EFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTVDVVRK 263 EF PER ENG+ +PF+ F AGPR C+G++ A ++MK + A ++ E+ + + + Sbjct: 382 EFIPERH--ENGS--RVAPFKMIPFSAGPRNCIGQKFAQLEMKMMLAKIVREYELLPMGQ 437 Query: 262 NAGSSAPEHVLSVTLRMKGGLPVQIRRR 179 E ++++ LR + G + +R+R Sbjct: 438 RV-----ECIVNIVLRSETGFQLGMRKR 460
>C72A1_CATRO (Q05047) Cytochrome P450 72A1 (EC 1.3.3.9) (CYPLXXII) (Secologanin| synthase) (SLS) Length = 524 Score = 47.4 bits (111), Expect = 2e-05 Identities = 25/65 (38%), Positives = 36/65 (55%) Frame = -3 Query: 466 AIWGKDCAEFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEE 287 +IWG+D EF P R++ + A ++ Y F GPR CLG+ A +Q K A +L+ Sbjct: 432 SIWGEDAMEFNPMRFV-DGVANATKNNVTYLPFSWGPRVCLGQNFALLQAKLGLAMILQR 490 Query: 286 FTVDV 272 F DV Sbjct: 491 FKFDV 495
>CCD1P_DROME (P82712) Probable cytochrome P450 12d1 proximal, mitochondrial| precursor (EC 1.14.-.-) (CYPXIID1) Length = 521 Score = 47.4 bits (111), Expect = 2e-05 Identities = 24/61 (39%), Positives = 34/61 (55%), Gaps = 2/61 (3%) Frame = -3 Query: 442 EFKPERWLG--ENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTVDVV 269 EF PERWL E G SPF + F GPR C+GK + ++M++ A ++ F V+ Sbjct: 434 EFLPERWLRDPETGKKMQVSPFTFLPFGFGPRMCIGKRVVDLEMETTVAKLIRNFHVEFN 493 Query: 268 R 266 R Sbjct: 494 R 494
>CCD1D_DROME (Q7KR10) Probable cytochrome P450 12d1 distal, mitochondrial| precursor (EC 1.14.-.-) (CYPXIID1) Length = 521 Score = 47.4 bits (111), Expect = 2e-05 Identities = 24/61 (39%), Positives = 34/61 (55%), Gaps = 2/61 (3%) Frame = -3 Query: 442 EFKPERWLG--ENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTVDVV 269 EF PERWL E G SPF + F GPR C+GK + ++M++ A ++ F V+ Sbjct: 434 EFLPERWLRDPETGKKMQVSPFTFLPFGFGPRMCIGKRVVDLEMETTVAKLIRNFHVEFN 493 Query: 268 R 266 R Sbjct: 494 R 494
>PID6_FUSSO (P38364) Pisatin demethylase (EC 1.14.-.-) (Cytochrome P450 57A2)| Length = 506 Score = 47.4 bits (111), Expect = 2e-05 Identities = 21/65 (32%), Positives = 35/65 (53%) Frame = -3 Query: 466 AIWGKDCAEFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEE 287 AI+G D + F+PERWL G F F AG R+C+GK ++ ++M ++ Sbjct: 417 AIFGNDASVFRPERWLETKGNLNIGGSF---AFGAGSRSCIGKNISILEMSKAIPQIVRN 473 Query: 286 FTVDV 272 F +++ Sbjct: 474 FDIEI 478
>CP52A_CANTR (P10615) Cytochrome P450 52A1 (EC 1.14.14.-) (CYPLIIA1)| (Alkane-inducible P450-ALK1) Length = 543 Score = 47.0 bits (110), Expect = 2e-05 Identities = 23/63 (36%), Positives = 35/63 (55%), Gaps = 3/63 (4%) Frame = -3 Query: 463 IWGKDCAEFKPERWLGENGAFRPESP---FRYTVFHAGPRTCLGKEMAYVQMKSIAASVL 293 I+G+D F+PERW F PE+ + Y F+ GPR CLG++ A + + +L Sbjct: 452 IYGEDAYVFRPERW------FEPETRKLGWAYVPFNGGPRICLGQQFALTEASYVTVRLL 505 Query: 292 EEF 284 +EF Sbjct: 506 QEF 508
>C4D14_DROME (O46051) Probable cytochrome P450 4d14 (EC 1.14.-.-) (CYPIVD14)| Length = 507 Score = 47.0 bits (110), Expect = 2e-05 Identities = 30/92 (32%), Positives = 49/92 (53%) Frame = -3 Query: 451 DCAEFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTVDV 272 D +F P+R+ E SPF YT F AGPR C+G++ A ++MKS + ++ F + Sbjct: 422 DPEKFIPDRFSMERKG--EISPFAYTPFSAGPRNCIGQKFAMLEMKSTISKMVRHFELLP 479 Query: 271 VRKNAGSSAPEHVLSVTLRMKGGLPVQIRRRV 176 + + + VL+V LR G+ ++ RV Sbjct: 480 LGEEV-----QPVLNVILRSTTGINCGLKPRV 506
>CP52W_CANAP (Q12573) Cytochrome P450 52E2 (EC 1.14.14.-) (CYPLIIE2)| Length = 519 Score = 47.0 bits (110), Expect = 2e-05 Identities = 22/63 (34%), Positives = 32/63 (50%) Frame = -3 Query: 469 AAIWGKDCAEFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLE 290 A IWG D F+P+RW A S + Y F+ GPR CLG++ A + + + Sbjct: 423 AGIWGPDSTSFRPDRWNEPREALA--SGWDYIPFNGGPRICLGQQFALTEASYTLVRICQ 480 Query: 289 EFT 281 EF+ Sbjct: 481 EFS 483
>CP52K_CANMA (Q12589) Cytochrome P450 52A11 (EC 1.14.14.-) (CYPLIIA11)| (Alkane-inducible P450-ALK8) Length = 519 Score = 47.0 bits (110), Expect = 2e-05 Identities = 28/94 (29%), Positives = 47/94 (50%), Gaps = 3/94 (3%) Frame = -3 Query: 460 WGKDCAEFKPERWLGENGAFRPESP---FRYTVFHAGPRTCLGKEMAYVQMKSIAASVLE 290 +GKD EF+PERW F PE + + F+ GPR CLG++ A + + +++ Sbjct: 432 YGKDANEFRPERW------FEPEVRKLGWAFLPFNGGPRICLGQQFALTEASYVLVRLIQ 485 Query: 289 EFTVDVVRKNAGSSAPEHVLSVTLRMKGGLPVQI 188 F + +A P + +T+ + G PV+I Sbjct: 486 SFETLELSPDA-PYPPAKLTHLTMCLFDGAPVRI 518
>CP52J_CANMA (Q12588) Cytochrome P450 52A10 (EC 1.14.14.-) (CYPLIIA10)| (Alkane-inducible P450-ALK7) Length = 519 Score = 47.0 bits (110), Expect = 2e-05 Identities = 28/93 (30%), Positives = 47/93 (50%), Gaps = 3/93 (3%) Frame = -3 Query: 460 WGKDCAEFKPERWLGENGAFRPESP---FRYTVFHAGPRTCLGKEMAYVQMKSIAASVLE 290 +GKD EF+PERW F PE + + F+ GPR CLG++ A + + A +++ Sbjct: 432 YGKDANEFRPERW------FEPEVRKLGWAFLPFNGGPRICLGQQFALTEASYVLARLIQ 485 Query: 289 EFTVDVVRKNAGSSAPEHVLSVTLRMKGGLPVQ 191 F + A + P + +T+ + G PV+ Sbjct: 486 SFETLELSPEA-AYPPAKLSHLTMCLFDGTPVR 517
>C12B1_DROAC (O44220) Cytochrome P450 12b1, mitochondrial precursor (EC| 1.14.-.-) (CYPXIIB1) Length = 532 Score = 47.0 bits (110), Expect = 2e-05 Identities = 23/63 (36%), Positives = 35/63 (55%), Gaps = 8/63 (12%) Frame = -3 Query: 442 EFKPERWLGENG--------AFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEE 287 +F PERWL + A R +PF Y F GPRTC+GK +A ++M+++ +L Sbjct: 441 QFMPERWLKADTDPDVKACPAARSRNPFVYLAFGFGPRTCIGKRIAELEMETLLTRLLRR 500 Query: 286 FTV 278 + V Sbjct: 501 YQV 503
>CP4P1_DROME (Q9V558) Cytochrome P450 4p1 (EC 1.14.-.-) (CYPIVP1)| Length = 513 Score = 46.6 bits (109), Expect = 3e-05 Identities = 29/91 (31%), Positives = 50/91 (54%), Gaps = 3/91 (3%) Frame = -3 Query: 442 EFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTVDVVRK 263 EF+PER+L EN + + Y F AG R C+GK+ A +MK++ +L++F V Sbjct: 430 EFRPERFLPEN--VQDRHTYAYVPFSAGQRNCIGKKYAMQEMKTLMVVLLKQFKV----- 482 Query: 262 NAGSSAPEHVL---SVTLRMKGGLPVQIRRR 179 + P+ ++ +TLR + + V++ RR Sbjct: 483 -LKAIDPQKIVFHTGITLRTQDKIRVKLVRR 512
>CP4E2_DROME (Q27606) Cytochrome P450 4e2 (EC 1.14.-.-) (CYPIVE2)| Length = 526 Score = 46.6 bits (109), Expect = 3e-05 Identities = 21/59 (35%), Positives = 35/59 (59%) Frame = -3 Query: 454 KDCAEFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTV 278 KD +F+PER+ E PF Y F AGPR C+G++ A +++K++ + ++ F V Sbjct: 414 KDPHKFRPERFELEK-----PGPFEYVPFSAGPRNCIGQKFALLEIKTVVSKIIRNFEV 467
>CP4P3_DROME (Q9V559) Probable cytochrome P450 4p3 (EC 1.14.-.-) (CYPIVP3)| Length = 515 Score = 46.6 bits (109), Expect = 3e-05 Identities = 29/91 (31%), Positives = 50/91 (54%), Gaps = 3/91 (3%) Frame = -3 Query: 442 EFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTVDVVRK 263 EF+PER+L EN R + Y F AG R C+G++ A +MK++ ++L++F + Sbjct: 432 EFRPERFLPENSQNR--HTYAYIPFSAGQRNCIGQKFAMQEMKTLMVALLKQFQI----- 484 Query: 262 NAGSSAPEHVL---SVTLRMKGGLPVQIRRR 179 P+ ++ +TLR K + V++ RR Sbjct: 485 -LPEIDPKTIVFQTGLTLRTKNQIHVKLVRR 514
>CP4E1_DROME (Q9V4T5) Probable cytochrome P450 4e1 (EC 1.14.-.-) (CYPIVE1)| Length = 531 Score = 46.6 bits (109), Expect = 3e-05 Identities = 21/59 (35%), Positives = 35/59 (59%) Frame = -3 Query: 454 KDCAEFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTV 278 KD +F+PER+ E PF Y F AGPR C+G++ A +++K++ + ++ F V Sbjct: 414 KDPHKFQPERFDREK-----PGPFEYVPFSAGPRNCIGQKFALLEIKTVVSKIIRNFEV 467
>C4AC1_DROME (Q9VMS9) Probable cytochrome P450 4ac1 (EC 1.14.-.-) (CYPIVAC1)| Length = 509 Score = 46.6 bits (109), Expect = 3e-05 Identities = 29/96 (30%), Positives = 50/96 (52%), Gaps = 7/96 (7%) Frame = -3 Query: 439 FKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTV------ 278 F+P+R+L EN R PF Y F AG R C+G++ A ++MK + A+V+ F + Sbjct: 426 FQPDRFLPENTVNR--HPFAYVPFSAGQRNCIGQKFAILEMKVLLAAVIRNFKLLPATQL 483 Query: 277 -DVVRKNAGSSAPEHVLSVTLRMKGGLPVQIRRRVE 173 D+ +N + LR + + V++ +RV+ Sbjct: 484 EDLTFEN----------GIVLRTQENIKVKLSKRVK 509
>CP52T_CANMA (Q12585) Cytochrome P450 52D1 (EC 1.14.14.-) (CYPLIID1)| (Alkane-inducible P450-ALK4) Length = 505 Score = 46.6 bits (109), Expect = 3e-05 Identities = 24/89 (26%), Positives = 45/89 (50%) Frame = -3 Query: 454 KDCAEFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTVD 275 KD F+PERW E + + Y F+ GPR CLG++ A + + + + +T Sbjct: 412 KDALIFRPERWC-EEPLIKKNLAWSYLPFNGGPRICLGQQFALTEASYVLTRLAQCYTKI 470 Query: 274 VVRKNAGSSAPEHVLSVTLRMKGGLPVQI 188 ++ N+ P+ + +T+ + G+ V+I Sbjct: 471 SLQPNSFEYPPKKQVHLTMSLLDGVHVKI 499
>C4AC3_DROME (Q9VMS7) Probable cytochrome P450 4ac3 (EC 1.14.-.-) (CYPIVAC3)| Length = 509 Score = 46.2 bits (108), Expect = 4e-05 Identities = 21/53 (39%), Positives = 33/53 (62%) Frame = -3 Query: 442 EFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEF 284 +F PER+L EN R PF + F AGPR C+G++ +++K + A+V+ F Sbjct: 425 QFLPERFLPENSVNR--HPFAFVPFSAGPRNCIGQKFGVLEIKVLLAAVIRNF 475
>PID9_FUSSO (Q12645) Pisatin demethylase (EC 1.14.-.-) (Cytochrome P450 57A1)| Length = 515 Score = 46.2 bits (108), Expect = 4e-05 Identities = 21/65 (32%), Positives = 35/65 (53%) Frame = -3 Query: 466 AIWGKDCAEFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEE 287 AI+G D + F+PERWL N F F AG R+C+GK ++ ++M ++ Sbjct: 417 AIFGNDASIFRPERWLEANENINIGGSF---AFGAGSRSCIGKNISILEMSKAIPQIVRN 473 Query: 286 FTVDV 272 F +++ Sbjct: 474 FDIEI 478
>C12B2_DROME (Q9V8M2) Probable cytochrome P450 12b2, mitochondrial precursor (EC| 1.14.-.-) (CYPXIIB2) Length = 561 Score = 45.8 bits (107), Expect = 5e-05 Identities = 23/64 (35%), Positives = 36/64 (56%), Gaps = 8/64 (12%) Frame = -3 Query: 445 AEFKPERWLGEN--------GAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLE 290 +EF PERWL + A R +PF Y F GPRTC+GK +A ++++++ +L Sbjct: 465 SEFIPERWLKSDLAPDIQACPAARTRNPFVYLPFGFGPRTCIGKRIAELEIETLLVRLLR 524 Query: 289 EFTV 278 + V Sbjct: 525 SYKV 528
>CP52M_DEBHA (Q9Y758) Cytochrome P450 52A13 (EC 1.14.14.-) (Alkane hydroxylase| 2) (Alkane-inducible p450alk 2) (DH-ALK2) Length = 519 Score = 45.8 bits (107), Expect = 5e-05 Identities = 23/59 (38%), Positives = 32/59 (54%) Frame = -3 Query: 460 WGKDCAEFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEF 284 +GKD EFKPERW A + + Y F+ GPR CLG++ A + I +L+ F Sbjct: 434 YGKDADEFKPERW-----AESRKLGWAYVPFNGGPRICLGQQFALTEASYIVTRLLQMF 487
>CP4B1_RAT (P15129) Cytochrome P450 4B1 (EC 1.14.14.1) (CYPIVB1) (P450-isozyme| 5) (P450 L-2) Length = 510 Score = 45.8 bits (107), Expect = 5e-05 Identities = 33/97 (34%), Positives = 49/97 (50%), Gaps = 2/97 (2%) Frame = -3 Query: 469 AAIWGKDCAEFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVL- 293 + +W D F P R+ EN A R PF + F AGPR C+G++ A +MK + A L Sbjct: 415 STVW-PDPEVFDPLRFSPENAAGR--HPFAFMPFSAGPRNCIGQQFAMNEMKVVTALCLL 471 Query: 292 -EEFTVDVVRKNAGSSAPEHVLSVTLRMKGGLPVQIR 185 EF++D S P V + LR K G+ + ++ Sbjct: 472 RFEFSLD------PSKMPIKVPQLILRSKNGIHLYLK 502
>CP52V_CANAP (P43083) Cytochrome P450 52E1 (EC 1.14.14.-) (CYPLIIE1)| Length = 519 Score = 45.4 bits (106), Expect = 7e-05 Identities = 21/61 (34%), Positives = 31/61 (50%) Frame = -3 Query: 463 IWGKDCAEFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEF 284 IWG D F+P+RW A S + Y F+ GPR CLG++ A + + +EF Sbjct: 425 IWGPDATTFRPDRWNEPREALA--SGWDYIPFNGGPRICLGQQFALTEASYTIVRICQEF 482 Query: 283 T 281 + Sbjct: 483 S 483
>CP6B3_PAPPO (Q27756) Cytochrome P450 6B3 (EC 1.14.14.1) (CYPVIB4)| (CYP6B3V1/CYP6B3V2) Length = 498 Score = 45.4 bits (106), Expect = 7e-05 Identities = 31/88 (35%), Positives = 44/88 (50%) Frame = -3 Query: 442 EFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTVDVVRK 263 +F PER+ EN + P Y F AGPR CLG A Q++ VL ++ V+ K Sbjct: 414 KFDPERFNPEN--IKNRHPCAYLPFSAGPRNCLGLRFAKWQIEVCVVKVLSKYRVEPSNK 471 Query: 262 NAGSSAPEHVLSVTLRMKGGLPVQIRRR 179 ++G + + L KGG+ V I RR Sbjct: 472 SSGEFKFDPMRLFVL-PKGGIFVNIVRR 498
>AVNA_ASPPA (Q12732) Averantin oxidoreductase (EC 1.14.-.-) (Cytochrome P450| 60A1) Length = 495 Score = 45.1 bits (105), Expect = 9e-05 Identities = 22/53 (41%), Positives = 31/53 (58%) Frame = -3 Query: 442 EFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEF 284 EF PERW G+ G F + F GPR C+G+++AYV+M+ I +L F Sbjct: 406 EFLPERWQGQ-GEFAHDRREVSQPFSIGPRNCIGRQLAYVEMRLILVKLLWHF 457
>CP135_DROME (Q9VGB5) Probable cytochrome P450 313a5 (EC 1.14.-.-)| (CYPCCCXIIIA5) Length = 487 Score = 45.1 bits (105), Expect = 9e-05 Identities = 21/60 (35%), Positives = 31/60 (51%) Frame = -3 Query: 463 IWGKDCAEFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEF 284 IWG F P+ +L EN RP P+ Y F G +TCLG +++ + K A +L + Sbjct: 397 IWGPQANAFNPDNFLPENKRARP--PYSYLPFSKGKKTCLGWKLSLISAKLALAKILRNY 454
>CP52H_CANTR (P30610) Cytochrome P450 52A8 (EC 1.14.14.-) (CYPLIIA8)| (Alkane-inducible P450-ALK5) Length = 517 Score = 45.1 bits (105), Expect = 9e-05 Identities = 26/91 (28%), Positives = 46/91 (50%) Frame = -3 Query: 460 WGKDCAEFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFT 281 +G D AEF+PERW N + + Y F+ GPR CLG++ A + + + + F Sbjct: 430 YGDDAAEFRPERW---NEPSTRKLGWAYLPFNGGPRICLGQQFALTEAGYVLVRLAQSFD 486 Query: 280 VDVVRKNAGSSAPEHVLSVTLRMKGGLPVQI 188 + K P+ + ++T+ ++ G V+I Sbjct: 487 T-LELKPPVVYPPKRLTNLTMSLQDGTIVKI 516
>CP56_YEAST (P21595) Cytochrome P450-DIT2 (EC 1.14.14.-) (Cytochrome P450 56)| Length = 489 Score = 44.7 bits (104), Expect = 1e-04 Identities = 22/64 (34%), Positives = 34/64 (53%), Gaps = 5/64 (7%) Frame = -3 Query: 460 WGKDCAEFKPERWLGENGAFRP-----ESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASV 296 WG +FKPERW + R ++ T FH G R CLG+++A +M+ A + Sbjct: 393 WGTTADDFKPERWGSDIETIRKNWRMAKNRCAVTGFHGGRRACLGEKLALTEMRISLAEM 452 Query: 295 LEEF 284 L++F Sbjct: 453 LKQF 456
>CP6D5_DROME (Q9VFP1) Probable cytochrome P450 6d5 (EC 1.14.-.-) (CYPVID5)| Length = 508 Score = 44.7 bits (104), Expect = 1e-04 Identities = 29/88 (32%), Positives = 44/88 (50%) Frame = -3 Query: 451 DCAEFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTVDV 272 D +KPER+L ENG + + Y F GPR C+G M V +K A VL F +++ Sbjct: 422 DPLAYKPERYL-ENG--KDYTQAAYLPFGEGPRMCIGARMGKVNVKIAIAKVLSNFDLEI 478 Query: 271 VRKNAGSSAPEHVLSVTLRMKGGLPVQI 188 ++ V + L K G+PV++ Sbjct: 479 RKEKC--EIEFGVYGIPLMPKSGVPVRL 504
>CP4B1_RABIT (P15128) Cytochrome P450 4B1 (EC 1.14.14.1) (CYPIVB1) (P450-isozyme| 5) Length = 506 Score = 44.3 bits (103), Expect = 2e-04 Identities = 31/95 (32%), Positives = 49/95 (51%), Gaps = 2/95 (2%) Frame = -3 Query: 463 IWGKDCAEFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVL--E 290 +W D F P R+ EN + R P+ + F AGPR C+G++ A +MK + A L Sbjct: 413 VW-PDPEVFDPLRFSPENSSGR--HPYAFIPFSAGPRNCIGQQFAMNEMKVVTALCLLRF 469 Query: 289 EFTVDVVRKNAGSSAPEHVLSVTLRMKGGLPVQIR 185 EF+VD +R P + + LR K G+ + ++ Sbjct: 470 EFSVDPLR------LPIKLPQLVLRSKNGIHLYLK 498
>CP2E1_BOVIN (O18963) Cytochrome P450 2E1 (EC 1.14.14.1) (CYPIIE1)| Length = 495 Score = 44.3 bits (103), Expect = 2e-04 Identities = 20/55 (36%), Positives = 35/55 (63%) Frame = -3 Query: 442 EFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTV 278 +FKPE +L ENG F+ F+ F AG R C+G+ +A +++ + A++L+ F + Sbjct: 408 KFKPEHFLNENGKFKYSDHFK--AFSAGKRVCVGEGLARMELFLLLAAILQHFNL 460
>CP3AA_MESAU (Q64148) Cytochrome P450 3A10 (EC 1.14.13.94) (CYPIIIA10)| (Lithocholate 6-beta-hydroxylase) (6 beta-hydroxylase) Length = 503 Score = 44.3 bits (103), Expect = 2e-04 Identities = 23/55 (41%), Positives = 30/55 (54%) Frame = -3 Query: 442 EFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTV 278 EF+PER+ EN P+ Y F GPR C+G A + MK SVL+ FT+ Sbjct: 413 EFRPERFSKENKG--SIDPYVYMPFGNGPRNCIGMRFALLSMKLAVVSVLQNFTL 465
>CP3AD_MOUSE (Q64464) Cytochrome P450 3A13 (EC 1.14.14.1) (CYPIIIA13)| Length = 503 Score = 43.9 bits (102), Expect = 2e-04 Identities = 22/55 (40%), Positives = 31/55 (56%) Frame = -3 Query: 442 EFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTV 278 EF+PER+ +N +P+ Y F +GPR C+G A + MK VL+ FTV Sbjct: 413 EFRPERFSKKNQD--SINPYMYLPFGSGPRNCIGMRFALINMKVALVRVLQNFTV 465
>CP2E1_RAT (P05182) Cytochrome P450 2E1 (EC 1.14.14.1) (CYPIIE1) (P450-J)| (P450RLM6) Length = 492 Score = 43.5 bits (101), Expect = 3e-04 Identities = 20/58 (34%), Positives = 36/58 (62%) Frame = -3 Query: 451 DCAEFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTV 278 D +FKPE +L ENG F+ F+ F AG R C+G+ +A +++ + +++L+ F + Sbjct: 404 DPEKFKPEHFLNENGKFKYSDYFK--AFSAGKRVCVGEGLARMELFLLLSAILQHFNL 459
>CP2E1_PIG (P79383) Cytochrome P450 2E1 (EC 1.14.14.1) (CYPIIE1) (P450-J)| (P-450-J) Length = 495 Score = 43.5 bits (101), Expect = 3e-04 Identities = 20/55 (36%), Positives = 34/55 (61%) Frame = -3 Query: 442 EFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTV 278 +FKPE +L ENG F+ F+ F AG R C+G+ +A +++ A++L+ F + Sbjct: 408 KFKPEHFLNENGKFKYSDHFK--AFSAGKRVCVGEGLARMELFLFMAAILQHFNL 460
>CP2E1_MESAU (P51581) Cytochrome P450 2E1 (EC 1.14.14.1) (CYPIIE1) (P450-J)| Length = 493 Score = 43.5 bits (101), Expect = 3e-04 Identities = 20/58 (34%), Positives = 35/58 (60%) Frame = -3 Query: 451 DCAEFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTV 278 D +FKPE +L ENG F+ F+ F AG R C+G+ +A +++ + ++L+ F + Sbjct: 405 DPEKFKPEHFLNENGKFKYSDHFK--AFSAGKRVCVGEGLARMELFLLLTAILQHFNL 460
>THAS_PIG (P47787) Thromboxane-A synthase (EC 5.3.99.5) (TXA synthase) (TXS)| Length = 534 Score = 43.5 bits (101), Expect = 3e-04 Identities = 26/80 (32%), Positives = 40/80 (50%) Frame = -3 Query: 439 FKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTVDVVRKN 260 F PER+ E A R + PF Y F AGPR+CLG ++ +++K +L +F + Sbjct: 452 FDPERFTAE--AQRLQQPFTYLPFGAGPRSCLGVQLGLLEIKLTLLHILRKFRFE----- 504 Query: 259 AGSSAPEHVLSVTLRMKGGL 200 + PE + + L K L Sbjct: 505 ---ACPETQVPLQLESKSAL 521
>CP51A_RAT (Q64654) Cytochrome P450 51A1 (EC 1.14.13.70) (CYPLI) (P450LI)| (Sterol 14-alpha demethylase) (Lanosterol 14-alpha demethylase) (LDM) (P450-14DM) Length = 503 Score = 43.5 bits (101), Expect = 3e-04 Identities = 21/58 (36%), Positives = 36/58 (62%) Frame = -3 Query: 442 EFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTVDVV 269 +F P+R+L +N A + F Y F AG C+G+ AYVQ+K+I +++L + D++ Sbjct: 420 DFNPDRYLQDNPASGEK--FAYVPFGAGRHRCIGENFAYVQIKTIWSTMLRLYEFDLI 475
>CP51A_PONPY (Q5RE72) Cytochrome P450 51A1 (EC 1.14.13.70) (CYPLI) (P450LI)| (Sterol 14-alpha demethylase) (Lanosterol 14-alpha demethylase) (LDM) (P450-14DM) (P45014DM) Length = 503 Score = 43.5 bits (101), Expect = 3e-04 Identities = 21/58 (36%), Positives = 36/58 (62%) Frame = -3 Query: 442 EFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTVDVV 269 +F P+R+L +N A + F Y F AG C+G+ AYVQ+K+I +++L + D++ Sbjct: 420 DFNPDRYLQDNPASGEK--FAYVPFGAGRHRCIGENFAYVQIKTIWSTMLRLYEFDLI 475
>CP51A_PIG (O46420) Cytochrome P450 51A1 (EC 1.14.13.70) (CYPLI) (P450LI)| (Sterol 14-alpha demethylase) (Lanosterol 14-alpha demethylase) (LDM) (P450-14DM) Length = 503 Score = 43.5 bits (101), Expect = 3e-04 Identities = 21/58 (36%), Positives = 36/58 (62%) Frame = -3 Query: 442 EFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTVDVV 269 +F P+R+L +N A + F Y F AG C+G+ AYVQ+K+I +++L + D++ Sbjct: 420 DFNPDRYLQDNPASGEK--FAYVPFGAGRHRCIGENFAYVQIKTIWSTMLRLYEFDLI 475
>CP51A_HUMAN (Q16850) Cytochrome P450 51A1 (EC 1.14.13.70) (CYPLI) (P450LI)| (Sterol 14-alpha demethylase) (Lanosterol 14-alpha demethylase) (LDM) (P450-14DM) (P45014DM) Length = 503 Score = 43.5 bits (101), Expect = 3e-04 Identities = 21/58 (36%), Positives = 36/58 (62%) Frame = -3 Query: 442 EFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTVDVV 269 +F P+R+L +N A + F Y F AG C+G+ AYVQ+K+I +++L + D++ Sbjct: 420 DFNPDRYLQDNPASGEK--FAYVPFGAGRHRCIGENFAYVQIKTIWSTMLRLYEFDLI 475
>CP4B1_MOUSE (Q64462) Cytochrome P450 4B1 (EC 1.14.14.1) (CYPIVB1)| Length = 511 Score = 43.5 bits (101), Expect = 3e-04 Identities = 33/97 (34%), Positives = 48/97 (49%), Gaps = 2/97 (2%) Frame = -3 Query: 469 AAIWGKDCAEFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVL- 293 +A+W D F P R+ EN R PF + F AGPR C+G++ A +MK + A L Sbjct: 416 SAVW-PDPEVFDPLRFSPENMTGR--HPFAFMPFSAGPRNCIGQQFAMNEMKVVTALCLL 472 Query: 292 -EEFTVDVVRKNAGSSAPEHVLSVTLRMKGGLPVQIR 185 EF+ D S P V + LR K G+ + ++ Sbjct: 473 RFEFSPD------PSKIPIKVPQLILRSKNGIHLYLK 503
>C4D21_DROME (Q9VLZ7) Probable cytochrome P450 4d21 (EC 1.14.-.-) (CYPIVD21)| Length = 511 Score = 43.1 bits (100), Expect = 4e-04 Identities = 18/52 (34%), Positives = 30/52 (57%) Frame = -3 Query: 439 FKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEF 284 FKPERW+ P Y F +GP+ C+G++ A +QMK++ + V+ + Sbjct: 427 FKPERWMDMKTTSNTP-PLAYIPFSSGPKNCIGQKFANLQMKALISKVIRHY 477
>CP6B1_PAPPO (Q04552) Cytochrome P450 6B1 (EC 1.14.14.1) (CYPVIB1)| (CYP6B1V1/CYP6B1V2/ CYP6B1V3) Length = 498 Score = 43.1 bits (100), Expect = 4e-04 Identities = 30/88 (34%), Positives = 43/88 (48%) Frame = -3 Query: 442 EFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTVDVVRK 263 +F PER+ EN + P Y F AGPR CLG A Q + VL ++ V+ K Sbjct: 414 KFDPERFNPEN--VKDRHPCAYLPFSAGPRNCLGMRFAKWQSEVCIMKVLSKYRVEPSMK 471 Query: 262 NAGSSAPEHVLSVTLRMKGGLPVQIRRR 179 ++G + + L KGG+ V + RR Sbjct: 472 SSGPFKFDPMRLFAL-PKGGIYVNLVRR 498
>C340_ORYLA (Q98T91) Cytochrome P450 3A40 (EC 1.14.14.1)| Length = 502 Score = 43.1 bits (100), Expect = 4e-04 Identities = 22/60 (36%), Positives = 31/60 (51%) Frame = -3 Query: 442 EFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTVDVVRK 263 +FKPER+ EN P+ Y F AGPR C+G A V MK +L+ + V ++ Sbjct: 414 KFKPERFSKENKD--TFDPYTYMPFGAGPRNCIGMRFALVMMKLAVVEILQTYDFSVCKE 471
>C4AD1_DROME (Q9V4T3) Probable cytochrome P450 4ad1 (EC 1.14.-.-) (CYPIVAD1)| Length = 516 Score = 43.1 bits (100), Expect = 4e-04 Identities = 29/106 (27%), Positives = 52/106 (49%), Gaps = 15/106 (14%) Frame = -3 Query: 451 DCAEFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTV-- 278 D F+PER+ G E+ F+ F AGPR C+ ++ A QMK++ + +L F + Sbjct: 412 DPCTFRPERFENPTGNVGIEA-FKSVPFSAGPRRCIAEKFAMYQMKALLSQLLRRFEILP 470 Query: 277 ----------DVVRKNAGSSA---PEHVLSVTLRMKGGLPVQIRRR 179 D R++ + P + VTL+ + G+ +++R+R Sbjct: 471 AVDGLPPGINDHSREDCVPQSEYDPVLNIRVTLKSENGIQIRLRKR 516
>CP192_CARAU (O73686) Cytochrome P450 19 type 2 (EC 1.14.14.1) (Ovarian| aromatase) (CYPXIXA2) (Estrogen synthetase) (P-450AROM) Length = 518 Score = 43.1 bits (100), Expect = 4e-04 Identities = 26/67 (38%), Positives = 38/67 (56%), Gaps = 1/67 (1%) Frame = -3 Query: 436 KPERWLGENGAFRPESPFRY-TVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTVDVVRKN 260 KP + +N F+ P R+ F +GPR+C+GK MA V MKSI ++L F+V V+ Sbjct: 429 KPNEFSLDN--FQKNVPSRFFQPFGSGPRSCVGKHMAMVMMKSILVTLLSRFSVCPVKGC 486 Query: 259 AGSSAPE 239 S P+ Sbjct: 487 TVDSIPQ 493
>CP4X1_RAT (Q8K4D6) Cytochrome P450 4X1 (EC 1.14.14.1) (CYPIVX1)| Length = 507 Score = 43.1 bits (100), Expect = 4e-04 Identities = 33/100 (33%), Positives = 49/100 (49%), Gaps = 2/100 (2%) Frame = -3 Query: 466 AIWGKDCAEFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEE 287 A+W KD F P R+ EN R P + F +GPR C+G++ A +++K A L Sbjct: 416 AVW-KDPKVFDPLRFTKENSEQR--HPCAFLPFSSGPRNCIGQQFAMLELKVAIALTLLR 472 Query: 286 FTV--DVVRKNAGSSAPEHVLSVTLRMKGGLPVQIRRRVE 173 F V D+ R A SS LR K G+ + +++ E Sbjct: 473 FRVAADLTRPPAFSS------HTVLRPKHGIYLHLKKLPE 506
>CP52E_CANMA (P24458) Cytochrome P450 52A5 (EC 1.14.14.-) (CYPLIIA5)| (Alkane-inducible P450-ALK2-A) (CYP52A3-B) Length = 523 Score = 42.7 bits (99), Expect = 5e-04 Identities = 21/62 (33%), Positives = 32/62 (51%), Gaps = 3/62 (4%) Frame = -3 Query: 460 WGKDCAEFKPERWLGENGAFRPESP---FRYTVFHAGPRTCLGKEMAYVQMKSIAASVLE 290 +GKD EF+PERW F P + + Y F+ GPR CLG++ A + + + + Sbjct: 437 YGKDAYEFRPERW------FEPSTRKLGWAYVPFNGGPRICLGQQFALTEASYVITRLAQ 490 Query: 289 EF 284 F Sbjct: 491 MF 492
>CP4E5_DROMT (O44221) Cytochrome P450 4e5, mitochondrial precursor (EC 1.14.-.-)| (CYPIVE5) Length = 522 Score = 42.7 bits (99), Expect = 5e-04 Identities = 17/53 (32%), Positives = 31/53 (58%) Frame = -3 Query: 436 KPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTV 278 +P R+ E + PF Y F AGPR C+G++ A +++K++ + ++ F V Sbjct: 414 EPHRFYPERFEKQKPGPFEYVPFSAGPRNCIGQKFALLELKTVISKLVRTFEV 466
>CP2M1_ONCMY (Q92088) Cytochrome P450 2M1 (EC 1.14.14.1) (CYPIIM1) (Lauric acid| omega-6-hydroxylase) (LMC1) Length = 499 Score = 42.7 bits (99), Expect = 5e-04 Identities = 26/74 (35%), Positives = 36/74 (48%) Frame = -3 Query: 454 KDCAEFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTVD 275 K+ EF PE +L ENG F+ F F G R C G+ +A V++ SVL+ FT Sbjct: 408 KNPDEFDPENFLDENGVFKKNDGF--FAFGVGKRACPGEALARVELFLFFTSVLQRFTF- 464 Query: 274 VVRKNAGSSAPEHV 233 G+ PE + Sbjct: 465 -----TGTKPPEEI 473
>CP52F_CANTR (P30608) Cytochrome P450 52A6 (EC 1.14.14.-) (CYPLIIA6)| (Alkane-inducible P450-ALK3) Length = 524 Score = 42.7 bits (99), Expect = 5e-04 Identities = 20/62 (32%), Positives = 33/62 (53%), Gaps = 3/62 (4%) Frame = -3 Query: 460 WGKDCAEFKPERWLGENGAFRPESP---FRYTVFHAGPRTCLGKEMAYVQMKSIAASVLE 290 +GKD +F+PERW F P + + Y F+ GPR CLG++ A + + +++ Sbjct: 438 YGKDADDFRPERW------FEPSTKKLGWAYVPFNGGPRICLGQQFALTEASYVITRLVQ 491 Query: 289 EF 284 F Sbjct: 492 MF 493
>CP2E1_MOUSE (Q05421) Cytochrome P450 2E1 (EC 1.14.14.1) (CYPIIE1) (P450-J)| (P450-ALC) Length = 493 Score = 42.7 bits (99), Expect = 5e-04 Identities = 20/58 (34%), Positives = 35/58 (60%) Frame = -3 Query: 451 DCAEFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTV 278 D FKPE +L ENG F+ F+ F AG R C+G+ +A +++ + +++L+ F + Sbjct: 405 DPETFKPEHFLNENGKFKYSDYFK--AFSAGKRVCVGEGLARMELFLLLSAILQHFNL 460
>CP131_DROME (Q9VFJ0) Probable cytochrome P450 313a1 (EC 1.14.-.-)| (CYPCCCXIIIA1) Length = 492 Score = 42.4 bits (98), Expect = 6e-04 Identities = 18/62 (29%), Positives = 29/62 (46%) Frame = -3 Query: 463 IWGKDCAEFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEF 284 +WG D F P+ +L EN + P+ Y F G R C+G + A + K +L + Sbjct: 402 VWGPDADNFNPDNFLAEN--MEQKHPYAYIPFARGKRNCIGSKYAMMSSKFALCRILRNY 459 Query: 283 TV 278 + Sbjct: 460 KI 461
>CP4F2_HUMAN (P78329) Cytochrome P450 4F2 (EC 1.14.13.30) (CYPIVF2)| (Leukotriene-B(4) omega-hydroxylase) (Leukotriene-B(4) 20-monooxygenase) (Cytochrome P450-LTB-omega) Length = 520 Score = 42.4 bits (98), Expect = 6e-04 Identities = 29/93 (31%), Positives = 44/93 (47%) Frame = -3 Query: 466 AIWGKDCAEFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEE 287 A+W D + P R+ EN + SP + F AGPR C+G+ A +MK + A L Sbjct: 432 AVW-PDPEVYDPFRFDPEN--IKERSPLAFIPFSAGPRNCIGQTFAMAEMKVVLALTLLR 488 Query: 286 FTVDVVRKNAGSSAPEHVLSVTLRMKGGLPVQI 188 F R + P + LR +GGL +++ Sbjct: 489 F-----RVLPDHTEPRRKPELVLRAEGGLWLRV 516
>C4D20_DROME (Q9W011) Probable cytochrome P450 4d20 (EC 1.14.-.-) (CYPIVD20)| Length = 510 Score = 42.4 bits (98), Expect = 6e-04 Identities = 26/91 (28%), Positives = 48/91 (52%) Frame = -3 Query: 451 DCAEFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTVDV 272 D F+PER+L + + + F Y F AGP+ C+G++ A ++MK + + VL + + Sbjct: 423 DPLSFRPERFLEDQE--QGHNTFAYVPFSAGPKNCIGQKFAVLEMKVLISKVLRFYELLP 480 Query: 271 VRKNAGSSAPEHVLSVTLRMKGGLPVQIRRR 179 + + + +L+ LR G+ V +R R Sbjct: 481 LGEEL-----KPMLNFILRSASGINVGLRPR 506
>CP19A_RAT (P22443) Cytochrome P450 19A1 (EC 1.14.14.1) (Aromatase) (CYPXIX)| (Estrogen synthetase) (P-450AROM) Length = 508 Score = 42.4 bits (98), Expect = 6e-04 Identities = 24/68 (35%), Positives = 37/68 (54%), Gaps = 1/68 (1%) Frame = -3 Query: 436 KPERWLGENGAFRPESPFRY-TVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTVDVVRKN 260 KP + EN F P+RY F GPR+C GK +A V MK + ++L+ F V ++K Sbjct: 409 KPNEFTLEN--FEKNVPYRYFQPFGFGPRSCAGKYIAMVMMKVVLVTLLKRFHVKTLQKR 466 Query: 259 AGSSAPEH 236 + P++ Sbjct: 467 CIENMPKN 474
>CP52C_CANMA (P16496) Cytochrome P450 52A3 (EC 1.14.14.-) (CYPLIIA3)| (Alkane-inducible P450-ALK1-A) (P450-CM1) (CYP52A3-A) (Cytochrome P-450ALK) Length = 522 Score = 42.4 bits (98), Expect = 6e-04 Identities = 21/62 (33%), Positives = 33/62 (53%), Gaps = 3/62 (4%) Frame = -3 Query: 460 WGKDCAEFKPERWLGENGAFRPESP---FRYTVFHAGPRTCLGKEMAYVQMKSIAASVLE 290 +G+D EF+PERW F P + + Y F+ GPR CLG++ A + + A + + Sbjct: 436 YGEDAYEFRPERW------FEPSTRKLGWAYLPFNGGPRICLGQQFALTEASYVIARLAQ 489 Query: 289 EF 284 F Sbjct: 490 MF 491
>C4AC2_DROME (Q9VMS8) Probable cytochrome P450 4ac2 (EC 1.14.-.-) (CYPIVAC2)| Length = 497 Score = 42.4 bits (98), Expect = 6e-04 Identities = 19/54 (35%), Positives = 33/54 (61%) Frame = -3 Query: 439 FKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTV 278 F+P+R+ EN R PF + F AG R C+G++ A +++K + A+V+ F + Sbjct: 413 FQPDRFFPENTVNR--HPFAFVPFSAGQRNCIGQKFAILEIKVLLAAVIRNFKI 464
>CP4FC_HUMAN (Q9HCS2) Cytochrome P450 4F12 (EC 1.14.14.1) (CYPIVF12)| Length = 524 Score = 42.4 bits (98), Expect = 6e-04 Identities = 29/92 (31%), Positives = 45/92 (48%) Frame = -3 Query: 463 IWGKDCAEFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEF 284 +W D + P R+ EN R SP + F AGPR C+G+ A +MK + A +L F Sbjct: 433 VW-PDPEVYDPFRFDPENSKGR--SPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHF 489 Query: 283 TVDVVRKNAGSSAPEHVLSVTLRMKGGLPVQI 188 R + P L + +R +GGL +++ Sbjct: 490 -----RFLPDHTEPRRKLELIMRAEGGLWLRV 516
>CP4B1_HUMAN (P13584) Cytochrome P450 4B1 (EC 1.14.14.1) (CYPIVB1) (P450-HP)| Length = 511 Score = 42.4 bits (98), Expect = 6e-04 Identities = 31/97 (31%), Positives = 48/97 (49%), Gaps = 2/97 (2%) Frame = -3 Query: 469 AAIWGKDCAEFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVL- 293 +A+W D F R+ EN + R PF + F AGPR C+G++ A +MK + A L Sbjct: 416 SAVW-PDPEVFDSLRFSTENASKR--HPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLL 472 Query: 292 -EEFTVDVVRKNAGSSAPEHVLSVTLRMKGGLPVQIR 185 EF++D S P + + LR K G + ++ Sbjct: 473 RFEFSLD------PSRLPIKMPQLVLRSKNGFHLHLK 503
>CP4X1_HUMAN (Q8N118) Cytochrome P450 4X1 (EC 1.14.14.1) (CYPIVX1)| Length = 509 Score = 42.0 bits (97), Expect = 8e-04 Identities = 32/100 (32%), Positives = 50/100 (50%), Gaps = 2/100 (2%) Frame = -3 Query: 466 AIWGKDCAEFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEE 287 A+W K+ F P R+ EN R P+ Y F AG R C+G+E A +++K A +L Sbjct: 418 AVW-KNPKVFDPLRFSQENSDQR--HPYAYLPFSAGSRNCIGQEFAMIELKVTIALILLH 474 Query: 286 F--TVDVVRKNAGSSAPEHVLSVTLRMKGGLPVQIRRRVE 173 F T D R + P H + L+ K G+ + +++ E Sbjct: 475 FRVTPDPTRP---LTFPNHFI---LKPKNGMYLHLKKLSE 508
>CP3AI_RAT (Q64581) Cytochrome P450 3A18 (EC 1.14.14.1) (CYPIIIA18)| (P450(6)beta-2) Length = 497 Score = 42.0 bits (97), Expect = 8e-04 Identities = 22/60 (36%), Positives = 28/60 (46%) Frame = -3 Query: 442 EFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTVDVVRK 263 EF PER+ EN P+ Y F GPR C+G A + MK VL+ F + K Sbjct: 413 EFNPERFSKENKG--SIDPYVYLPFGNGPRNCIGMRFALISMKLAVIGVLQNFNIQPCEK 470
>C28D2_DROME (Q9VMT6) Probable cytochrome P450 28d2 (EC 1.14.-.-) (CYPXXVIIID2)| Length = 501 Score = 41.6 bits (96), Expect = 0.001 Identities = 27/87 (31%), Positives = 38/87 (43%), Gaps = 2/87 (2%) Frame = -3 Query: 454 KDCAEFKPERWLGENGAFRPESPFR--YTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFT 281 +D FKPER+L NG R Y F GPR C G A Q+K+ +L F Sbjct: 409 EDPLTFKPERFLESNGGGMKSYRDRGVYLAFGDGPRHCPGMRFALTQLKAALVEILRNFE 468 Query: 280 VDVVRKNAGSSAPEHVLSVTLRMKGGL 200 + V K + + + +KGG+ Sbjct: 469 IKVNPKTRSDNQIDDTFFMA-TLKGGI 494
>CP17A_SQUAC (Q92113) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 509 Score = 41.6 bits (96), Expect = 0.001 Identities = 21/56 (37%), Positives = 32/56 (57%) Frame = -3 Query: 439 FKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTVDV 272 F P R+L E+G + S Y F AG R CLG+ +A +++ + +L+ FTV V Sbjct: 415 FDPGRFLDEDGKYVCSSSESYLPFGAGTRVCLGEMLARMELFLFTSWILQRFTVQV 470
>CP51A_BOVIN (Q4PJW3) Cytochrome P450 51A1 (EC 1.14.13.70) (CYPLI) (P450LI)| (Sterol 14-alpha demethylase) (Lanosterol 14-alpha demethylase) (LDM) (P450-14DM) (P45014DM) Length = 502 Score = 41.6 bits (96), Expect = 0.001 Identities = 20/58 (34%), Positives = 36/58 (62%) Frame = -3 Query: 442 EFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTVDVV 269 +F P+R+L ++ A + F Y F AG C+G+ AYVQ+K+I +++L + D++ Sbjct: 419 DFNPDRYLEDSPASGEK--FAYVPFGAGRHRCIGENFAYVQIKTIWSTMLRLYEFDLI 474
>C11B1_MESAU (P97720) Cytochrome P450 11B1, mitochondrial precursor (EC| 1.14.15.4) (CYPXIB1) (P450C11) (Steroid 11-beta-hydroxylase) Length = 499 Score = 41.6 bits (96), Expect = 0.001 Identities = 21/55 (38%), Positives = 31/55 (56%) Frame = -3 Query: 439 FKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTVD 275 + P+RWL NG+F+ + F G R CLGK +A V+M + VL+ F V+ Sbjct: 422 YLPQRWLERNGSFQ------HLTFGFGVRQCLGKRLAQVEMLLLLHHVLKSFRVE 470
>C11B2_MESAU (Q64658) Cytochrome P450 11B2, mitochondrial precursor (EC| 1.14.15.4) (EC 1.14.15.5) (C450XIB2) (Aldosterone synthase) (P-450Aldo) (ALDOS) (Aldosterone-synthesizing enzyme) (Steroid 18-hydroxylase) (P-450C18) Length = 500 Score = 41.6 bits (96), Expect = 0.001 Identities = 21/55 (38%), Positives = 31/55 (56%) Frame = -3 Query: 439 FKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTVD 275 + P+RWL NG+F+ + F G R CLGK +A V+M + VL+ F V+ Sbjct: 423 YLPQRWLERNGSFQ------HLTFGFGVRQCLGKRLAQVEMLLLLHHVLKSFRVE 471
>CP4F5_RAT (P51870) Cytochrome P450 4F5 (EC 1.14.14.1) (CYPIVF5)| Length = 526 Score = 41.6 bits (96), Expect = 0.001 Identities = 30/89 (33%), Positives = 40/89 (44%) Frame = -3 Query: 466 AIWGKDCAEFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEE 287 ++W D F P R+ EN R SP + F AGPR C+G+ A +MK + A L Sbjct: 434 SVW-PDPEVFDPFRFDSENRQKR--SPLSFIPFSAGPRNCIGQTFAMNEMKVVVALTLLR 490 Query: 286 FTVDVVRKNAGSSAPEHVLSVTLRMKGGL 200 F R P + LR +GGL Sbjct: 491 F-----RVLPDDKEPRRKPEIILRAEGGL 514
>CP19A_ORENI (P70091) Cytochrome P450 19A1 (EC 1.14.14.1) (Aromatase) (CYPXIX)| (Estrogen synthetase) (P-450AROM) Length = 522 Score = 41.2 bits (95), Expect = 0.001 Identities = 20/46 (43%), Positives = 29/46 (63%) Frame = -3 Query: 415 ENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTV 278 EN RP + + F +GPR C+GK MA V MKSI ++L +++V Sbjct: 428 ENNVPRPPT---FQPFGSGPRACIGKHMAMVMMKSILVTLLSQYSV 470
>CP138_MYCTU (P63717) Putative cytochrome P450 138 (EC 1.14.-.-)| Length = 441 Score = 41.2 bits (95), Expect = 0.001 Identities = 26/87 (29%), Positives = 39/87 (44%) Frame = -3 Query: 439 FKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTVDVVRKN 260 F P+R++G SPF + F G R C+G A ++M + +VL FT++ Sbjct: 363 FDPQRYIGSK-----PSPFAWIPFGGGTRRCVGAAFANMEMDVVLRTVLRHFTLET---T 414 Query: 259 AGSSAPEHVLSVTLRMKGGLPVQIRRR 179 + H V K G V +RRR Sbjct: 415 TAAGERSHGRGVAFTPKDGGRVVMRRR 441
>CP138_MYCBO (P63718) Putative cytochrome P450 138 (EC 1.14.-.-)| Length = 441 Score = 41.2 bits (95), Expect = 0.001 Identities = 26/87 (29%), Positives = 39/87 (44%) Frame = -3 Query: 439 FKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTVDVVRKN 260 F P+R++G SPF + F G R C+G A ++M + +VL FT++ Sbjct: 363 FDPQRYIGSK-----PSPFAWIPFGGGTRRCVGAAFANMEMDVVLRTVLRHFTLET---T 414 Query: 259 AGSSAPEHVLSVTLRMKGGLPVQIRRR 179 + H V K G V +RRR Sbjct: 415 TAAGERSHGRGVAFTPKDGGRVVMRRR 441
>CP120_SYNY3 (Q59990) Putative cytochrome P450 120 (EC 1.14.-.-)| Length = 444 Score = 41.2 bits (95), Expect = 0.001 Identities = 21/56 (37%), Positives = 31/56 (55%) Frame = -3 Query: 451 DCAEFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEF 284 D +F PER+ + A PF + F G R CLGKE A ++MK A ++++F Sbjct: 358 DPEKFDPERFTPDGSATH-NPPFAHVPFGGGLRECLGKEFARLEMKLFATRLIQQF 412
>C12A5_DROME (Q9VE01) Probable cytochrome P450 12a5, mitochondrial precursor (EC| 1.14.-.-) (CYPXIIA5) Length = 536 Score = 41.2 bits (95), Expect = 0.001 Identities = 28/89 (31%), Positives = 47/89 (52%), Gaps = 11/89 (12%) Frame = -3 Query: 442 EFKPERWL-------GENGA--FRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLE 290 EF PERWL G+ A + ++PF + F GPR C+GK + ++++ A ++ Sbjct: 442 EFLPERWLRNASDSAGKCPANDLKTKNPFVFLPFGFGPRMCVGKRIVEMELELGTARLIR 501 Query: 289 EFTVDV--VRKNAGSSAPEHVLSVTLRMK 209 F V+ KNA SA ++ ++ L+ K Sbjct: 502 NFNVEFNHSTKNAFRSALINLPNIPLKFK 530
>CP52L_DEBHA (Q9Y757) Cytochrome P450 52A12 (EC 1.14.14.-) (Alkane hydroxylase| 1) (Alkane-inducible p450alk 1) (DH-ALK2) Length = 519 Score = 41.2 bits (95), Expect = 0.001 Identities = 21/62 (33%), Positives = 33/62 (53%), Gaps = 3/62 (4%) Frame = -3 Query: 460 WGKDCAEFKPERWLGENGAFRPESP---FRYTVFHAGPRTCLGKEMAYVQMKSIAASVLE 290 +GKD F+PERW F PE+ + + F+ GPR CLG++ A + + A + + Sbjct: 433 YGKDSEVFRPERW------FEPETRKLGWAFLPFNGGPRICLGQQFALTEASYVIARLAQ 486 Query: 289 EF 284 F Sbjct: 487 LF 488
>TRI11_FUSSP (O13317) Isotrichodermin C-15 hydroxylase (EC 1.14.-.-) (Cytochrome| P450 65A1) Length = 492 Score = 41.2 bits (95), Expect = 0.001 Identities = 20/55 (36%), Positives = 30/55 (54%) Frame = -3 Query: 442 EFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTV 278 +F PERWLG+ F + F GPR C+G +AY +M+ + A + EF + Sbjct: 408 DFIPERWLGDV-RFANDRLDAVKPFSIGPRNCIGMNLAYAEMRMMLARTVWEFDI 461
>CP52Q_CANMA (Q12587) Cytochrome P450 52C2 (EC 1.14.14.-) (CYPLIIC2)| (Alkane-inducible P450-ALK6-A) Length = 510 Score = 41.2 bits (95), Expect = 0.001 Identities = 26/90 (28%), Positives = 48/90 (53%), Gaps = 4/90 (4%) Frame = -3 Query: 460 WGKDCAEFKPERW--LGENG--AFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVL 293 +G+ EF PERW L + G AF P F GPR CLG++ A ++ + ++ Sbjct: 425 FGRKPEEFIPERWRDLPKTGGPAFMP--------FSTGPRMCLGQQFALIEASYVTIRLV 476 Query: 292 EEFTVDVVRKNAGSSAPEHVLSVTLRMKGG 203 + F+ ++ ++ AP+ +++ T+R+ G Sbjct: 477 QTFS--KLKSHSLEYAPKRLVAATIRLIDG 504
>CP17A_RAT (P11715) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 507 Score = 41.2 bits (95), Expect = 0.001 Identities = 20/57 (35%), Positives = 32/57 (56%) Frame = -3 Query: 442 EFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTVDV 272 +F PER+L G+ Y F AGPR+C+G+ +A ++ A +L+ F +DV Sbjct: 410 QFMPERFLDPTGSHLITPTQSYLPFGAGPRSCIGEALARQELFVFTALLLQRFDLDV 466
>CP341_MOUSE (Q9JMA7) Cytochrome P450 3A41 (EC 1.14.14.1)| Length = 504 Score = 41.2 bits (95), Expect = 0.001 Identities = 20/54 (37%), Positives = 29/54 (53%) Frame = -3 Query: 442 EFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFT 281 EF+PER+ EN P+ Y F GPR C+G A++ MK V++ F+ Sbjct: 414 EFQPERFSKENKG--SIDPYLYMPFGIGPRNCIGMRFAFMTMKLALTKVMQNFS 465
>STCF_EMENI (Q12609) Probable sterigmatocystin biosynthesis P450 monooxygenase| STCF (EC 1.14.-.-) (Cytochrome P450 60A2) Length = 506 Score = 40.8 bits (94), Expect = 0.002 Identities = 21/60 (35%), Positives = 33/60 (55%) Frame = -3 Query: 442 EFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTVDVVRK 263 EF PERW E G F + F GPR C+G+++A +M+ I +L F +++ R+ Sbjct: 394 EFIPERWEKE-GEFINDRREASQPFSIGPRNCIGRQLALAEMRLILVHLLWHFDIELDRR 452
>CP27B_RAT (O35132) 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial| precursor (EC 1.14.13.13) (Cytochrome P450 subfamily XXVIIB polypeptide 1) (Cytochrome p450 27B1) (Calcidiol 1-monooxygenase) (25-OHD-1 alpha-hydroxylase) (25-hydroxyvitamin D(3) 1 Length = 501 Score = 40.8 bits (94), Expect = 0.002 Identities = 20/54 (37%), Positives = 29/54 (53%) Frame = -3 Query: 439 FKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTV 278 F P RWLGE A PF F G R+C+G+ +A ++++ A +L F V Sbjct: 421 FNPARWLGEGPA---PHPFASLPFGFGKRSCIGRRLAELELQMALAQILTHFEV 471
>CP24A_HUMAN (Q07973) Cytochrome P450 24A1, mitochondrial precursor (EC| 1.14.-.-) (P450-CC24) (Vitamin D(3) 24-hydroxylase) (1,25-dihydroxyvitamin D(3) 24-hydroxylase) (24-OHase) Length = 514 Score = 40.8 bits (94), Expect = 0.002 Identities = 26/93 (27%), Positives = 46/93 (49%), Gaps = 1/93 (1%) Frame = -3 Query: 454 KDCAEFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTVD 275 +D ++F+PERWL E +PF + F G R C+G+ +A +Q+ ++ ++ + Sbjct: 430 EDSSQFRPERWLQEKEKI---NPFAHLPFGVGKRMCIGRRLAELQLHLALCWIVRKYDI- 485 Query: 274 VVRKNAGSSAPEHVL-SVTLRMKGGLPVQIRRR 179 A + P +L S TL LP+ +R Sbjct: 486 ----QATDNEPVEMLHSGTLVPSRELPIAFCQR 514
>CP11A_DASAM (Q92045) Cytochrome P450 11A1, mitochondrial precursor (EC| 1.14.15.6) (CYPXIA1) (P450(SCC)) (Cholesterol side-chain cleavage enzyme) (Cholesterol desmolase) (Fragment) Length = 514 Score = 40.8 bits (94), Expect = 0.002 Identities = 21/61 (34%), Positives = 35/61 (57%), Gaps = 1/61 (1%) Frame = -3 Query: 454 KDCAEFKPERWL-GENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTV 278 K+ ++ PERWL GE ++ FR+ F GPR C+G+ +A QM + +L+ F + Sbjct: 431 KNPEQYNPERWLKGE------DTHFRHLGFGFGPRQCIGRRIAETQMVLLMIHMLQNFKI 484 Query: 277 D 275 + Sbjct: 485 E 485
>THAS_HUMAN (P24557) Thromboxane-A synthase (EC 5.3.99.5) (TXA synthase) (TXS)| Length = 533 Score = 40.8 bits (94), Expect = 0.002 Identities = 21/52 (40%), Positives = 29/52 (55%) Frame = -3 Query: 439 FKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEF 284 F PER+ E A + PF Y F AGPR+CLG + +++K VL +F Sbjct: 451 FNPERFTAE--ARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKF 500
>C71AN_ARATH (Q9STL0) Cytochrome P450 71A23 (EC 1.14.-.-)| Length = 483 Score = 40.8 bits (94), Expect = 0.002 Identities = 24/62 (38%), Positives = 31/62 (50%) Frame = -3 Query: 469 AAIWGKDCAEFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLE 290 AA WG D EF+PER L FR + F F AG R C G A V + + A+++ Sbjct: 390 AATWGPDANEFRPERHLESPSDFRGQD-FELIPFGAGRRMCPGISFAVVLNEVVLANLVH 448 Query: 289 EF 284 F Sbjct: 449 GF 450
>C13B1_CAEEL (O17624) Putative cytochrome P450 cyp-13B1 (EC 1.14.-.-)| Length = 527 Score = 40.8 bits (94), Expect = 0.002 Identities = 22/64 (34%), Positives = 33/64 (51%), Gaps = 4/64 (6%) Frame = -3 Query: 463 IWGKDCAEFKPERWLGENGAFRPESPFRYTV----FHAGPRTCLGKEMAYVQMKSIAASV 296 IWG++ +F PERWL E R+T+ F AGPR C+G + + K+ A + Sbjct: 422 IWGENADDFVPERWL--------EPSSRHTMSWIPFGAGPRQCVGMRLGLSEAKTALAHL 473 Query: 295 LEEF 284 L + Sbjct: 474 LRRY 477
>CP3A5_HUMAN (P20815) Cytochrome P450 3A5 (EC 1.14.14.1) (CYPIIIA5) (P450-PCN3)| (HLp2) Length = 502 Score = 40.8 bits (94), Expect = 0.002 Identities = 20/54 (37%), Positives = 29/54 (53%) Frame = -3 Query: 442 EFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFT 281 EF+PER+ + + P+ YT F GPR C+G A + MK VL+ F+ Sbjct: 413 EFRPERFSKKKDSI---DPYIYTPFGTGPRNCIGMRFALMNMKLALIRVLQNFS 463
>CP19A_MOUSE (P28649) Cytochrome P450 19A1 (EC 1.14.14.1) (Aromatase) (CYPXIX)| (Estrogen synthetase) (P-450AROM) Length = 503 Score = 40.8 bits (94), Expect = 0.002 Identities = 24/67 (35%), Positives = 34/67 (50%), Gaps = 1/67 (1%) Frame = -3 Query: 436 KPERWLGENGAFRPESPFRY-TVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTVDVVRKN 260 KP + EN F P+RY F GPR C GK +A V MK + ++L F V ++K Sbjct: 409 KPNEFTLEN--FEKNVPYRYFQPFGFGPRGCAGKYIAMVMMKVVLVTLLRRFQVKTLQKR 466 Query: 259 AGSSAPE 239 + P+ Sbjct: 467 CIENIPK 473
>CP3AP_MOUSE (O09158) Cytochrome P450 3A25 (EC 1.14.14.1) (CYPIIIA25)| Length = 503 Score = 40.4 bits (93), Expect = 0.002 Identities = 22/55 (40%), Positives = 28/55 (50%) Frame = -3 Query: 442 EFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTV 278 EF PER+ EN P+ Y F GPR C+G A + +K VL+ FTV Sbjct: 413 EFCPERFSKENKG--NIDPYIYMPFGNGPRNCIGMRFALISIKLAVIGVLQNFTV 465
>CP11A_RAT (P14137) Cytochrome P450 11A1, mitochondrial precursor (EC| 1.14.15.6) (CYPXIA1) (P450(scc)) (Cholesterol side-chain cleavage enzyme) (Cholesterol desmolase) Length = 526 Score = 40.4 bits (93), Expect = 0.002 Identities = 21/57 (36%), Positives = 33/57 (57%) Frame = -3 Query: 442 EFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTVDV 272 +F P RWL ++ + + FRY F G R CLG+ +A ++M +VLE F ++V Sbjct: 431 KFDPTRWLEKS---QNTTHFRYLGFGWGVRQCLGRRIAELEMTIFLINVLENFRIEV 484
>CP4FB_HUMAN (Q9HBI6) Cytochrome P450 4F11 (EC 1.14.14.1) (CYPIVF11)| Length = 524 Score = 40.4 bits (93), Expect = 0.002 Identities = 27/92 (29%), Positives = 43/92 (46%) Frame = -3 Query: 463 IWGKDCAEFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEF 284 +W D + P R+ EN + SP + F AGPR C+G+ A +MK + A L F Sbjct: 433 VW-PDPEVYDPFRFNQEN--IKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALTLLHF 489 Query: 283 TVDVVRKNAGSSAPEHVLSVTLRMKGGLPVQI 188 + + P + LR +GGL +++ Sbjct: 490 RILPTH-----TEPRRKPELILRAEGGLWLRV 516
>CP2E1_RABIT (P08682) Cytochrome P450 2E1 (EC 1.14.14.1) (CYPIIE1) (Isozyme 3A)| (P450-ALC) Length = 493 Score = 40.4 bits (93), Expect = 0.002 Identities = 19/58 (32%), Positives = 35/58 (60%) Frame = -3 Query: 451 DCAEFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTV 278 D +FKPE +L E G F+ F+ F AG R C+G+ +A +++ + +++L+ F + Sbjct: 405 DPEKFKPEHFLNEEGKFKYSDYFK--PFSAGKRVCVGEGLARMELFLLLSAILQHFNL 460
>CP3A1_RAT (P04800) Cytochrome P450 3A1 (EC 1.14.14.1) (CYPIIIA1) (P450-PCN1)| Length = 504 Score = 40.4 bits (93), Expect = 0.002 Identities = 21/54 (38%), Positives = 28/54 (51%) Frame = -3 Query: 442 EFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFT 281 EF+PER+ EN P+ Y F GPR C+G A + MK VL+ F+ Sbjct: 414 EFRPERFSKENKG--SIDPYVYLPFGNGPRNCIGMRFALMNMKLALTKVLQNFS 465
>CP19A_CALJA (Q95M61) Cytochrome P450 19A1 (EC 1.14.14.1) (Aromatase) (CYPXIX)| (Estrogen synthetase) (P-450AROM) Length = 503 Score = 40.0 bits (92), Expect = 0.003 Identities = 24/54 (44%), Positives = 30/54 (55%), Gaps = 1/54 (1%) Frame = -3 Query: 436 KPERWLGENGAFRPESPFRY-TVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTV 278 KP + EN F P+RY F GPR+C GK +A V MKSI ++L F V Sbjct: 409 KPNEFTLEN--FAKNVPYRYFQPFGFGPRSCAGKYIAMVMMKSILVTLLRRFHV 460
>CP11A_MOUSE (Q9QZ82) Cytochrome P450 11A1, mitochondrial precursor (EC| 1.14.15.6) (CYPXIA1) (P450(scc)) (Cholesterol side-chain cleavage enzyme) (Cholesterol desmolase) Length = 526 Score = 40.0 bits (92), Expect = 0.003 Identities = 20/57 (35%), Positives = 34/57 (59%) Frame = -3 Query: 442 EFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTVDV 272 +F P RWL ++ + + FRY F G R CLG+ +A ++M + ++LE F ++V Sbjct: 430 KFDPTRWLEKS---QNTTHFRYLGFGWGVRQCLGRRIAELEMTILLINLLENFRIEV 483
>CP27B_HUMAN (O15528) 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial| precursor (EC 1.14.13.13) (Cytochrome P450 subfamily XXVIIB polypeptide 1) (Cytochrome p450 27B1) (Calcidiol 1-monooxygenase) (25-OHD-1 alpha-hydroxylase) (25-hydroxyvitamin D(3) Length = 508 Score = 40.0 bits (92), Expect = 0.003 Identities = 19/54 (35%), Positives = 29/54 (53%) Frame = -3 Query: 439 FKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTV 278 F+P RWLGE PF F G R+C+G+ +A ++++ A +L F V Sbjct: 428 FRPARWLGEGPT---PHPFASLPFGFGKRSCMGRRLAELELQMALAQILTHFEV 478
>THAS_RAT (P49430) Thromboxane-A synthase (EC 5.3.99.5) (TXA synthase) (TXS)| Length = 533 Score = 40.0 bits (92), Expect = 0.003 Identities = 26/80 (32%), Positives = 37/80 (46%) Frame = -3 Query: 439 FKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTVDVVRKN 260 F PER+ E A + PF Y F AGPR+CLG + + +K VL +F + Sbjct: 451 FDPERFTAE--ARLQQKPFTYLPFGAGPRSCLGVRLGLLVVKLTLLQVLHKFRFE----- 503 Query: 259 AGSSAPEHVLSVTLRMKGGL 200 + PE + + L K L Sbjct: 504 ---ACPETQVPLQLESKSAL 520
>CP2E1_HUMAN (P05181) Cytochrome P450 2E1 (EC 1.14.14.1) (CYPIIE1) (P450-J)| Length = 493 Score = 40.0 bits (92), Expect = 0.003 Identities = 19/58 (32%), Positives = 33/58 (56%) Frame = -3 Query: 451 DCAEFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTV 278 D +FKPE +L ENG F+ F+ F G R C G+ +A +++ + ++L+ F + Sbjct: 405 DPEKFKPEHFLNENGKFKYSDYFK--PFSTGKRVCAGEGLARMELFLLLCAILQHFNL 460
>CP4F8_HUMAN (P98187) Cytochrome P450 4F8 (EC 1.14.14.1) (CYPIVF8)| Length = 520 Score = 40.0 bits (92), Expect = 0.003 Identities = 27/93 (29%), Positives = 44/93 (47%) Frame = -3 Query: 466 AIWGKDCAEFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEE 287 ++W D + P R+ EN R SP + F AGPR C+G++ A +MK + A L Sbjct: 432 SVW-PDPEVYDPFRFDPENAQKR--SPMAFIPFSAGPRNCIGQKFAMAEMKVVLALTLLR 488 Query: 286 FTVDVVRKNAGSSAPEHVLSVTLRMKGGLPVQI 188 F + + P + LR + GL +++ Sbjct: 489 FRILPDHRE-----PRRTPEIVLRAEDGLWLRV 516
>CP11A_MESAU (Q9EPT4) Cytochrome P450 11A1, mitochondrial precursor (EC| 1.14.15.6) (CYPXIA1) (P450(scc)) (Cholesterol side-chain cleavage enzyme) (Cholesterol desmolase) Length = 520 Score = 40.0 bits (92), Expect = 0.003 Identities = 20/57 (35%), Positives = 33/57 (57%) Frame = -3 Query: 442 EFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTVDV 272 +F P RWL ++ + + FRY F G R CLG+ +A ++M +VLE F +++ Sbjct: 430 KFDPTRWLEKS---KNTTHFRYLSFGWGVRQCLGRRIAELEMTIFLINVLENFRIEL 483
>CP301_DROME (Q9V6D6) Probable cytochrome P450 301a1, mitochondrial precursor| (EC 1.14.-.-) (CYPCCCIA1) Length = 553 Score = 40.0 bits (92), Expect = 0.003 Identities = 21/65 (32%), Positives = 32/65 (49%), Gaps = 2/65 (3%) Frame = -3 Query: 451 DCAEFKPERWLGENGAFRPES--PFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTV 278 D A F+PERWL P PF + G R CLG+ A ++M+ + A +L + + Sbjct: 466 DAATFRPERWLKPQHGGTPGKLHPFASLPYGYGARMCLGRRFADLEMQILLAKLLRNYKL 525 Query: 277 DVVRK 263 + K Sbjct: 526 EYNHK 530
>C6A18_DROME (Q9VB31) Probable cytochrome P450 6a18 (EC 1.14.-.-) (CYPVIA18)| Length = 507 Score = 39.7 bits (91), Expect = 0.004 Identities = 23/85 (27%), Positives = 40/85 (47%) Frame = -3 Query: 442 EFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTVDVVRK 263 EF+PER+ E A RP + F GPR C+G +Q + A +++ FT Sbjct: 422 EFRPERFSPEESAKRPS--VAWLPFGEGPRNCIGLRFGQMQARIGLAMLIKNFTFSPCSA 479 Query: 262 NAGSSAPEHVLSVTLRMKGGLPVQI 188 + ++ L +KGG+ +++ Sbjct: 480 TPDPLTFDPHSAILLGIKGGIQLKV 504
>CP2CL_CANFA (P56594) Cytochrome P450 2C21 (EC 1.14.14.1) (CYPIIC21) (DM1-1)| (Fragment) Length = 487 Score = 39.7 bits (91), Expect = 0.004 Identities = 18/55 (32%), Positives = 33/55 (60%) Frame = -3 Query: 442 EFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTV 278 +F P +L ENG+F+ F F AG R C+G+ +A +++ + ++L+ FT+ Sbjct: 403 QFDPGHFLDENGSFKKSDYFM--AFSAGKRVCVGEGLARMELFLLLTNILQHFTL 455
>CP3AG_MOUSE (Q64481) Cytochrome P450 3A16 (EC 1.14.14.1) (CYPIIIA16)| Length = 504 Score = 39.7 bits (91), Expect = 0.004 Identities = 21/54 (38%), Positives = 28/54 (51%) Frame = -3 Query: 442 EFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFT 281 EF+PER+ EN P+ Y F GPR C+G A + MK VL+ F+ Sbjct: 414 EFQPERFSKENKG--SIDPYVYLPFGNGPRNCIGMRFALMNMKLALIKVLQNFS 465
>CP3AB_MOUSE (Q64459) Cytochrome P450 3A11 (EC 1.14.14.1) (CYPIIIA11)| (P-450IIIAM1) (P-450UT) Length = 504 Score = 39.7 bits (91), Expect = 0.004 Identities = 20/54 (37%), Positives = 28/54 (51%) Frame = -3 Query: 442 EFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFT 281 EF+PER+ EN P+ Y F GPR CLG A + MK +++ F+ Sbjct: 414 EFQPERFSKENKG--SIDPYVYLPFGNGPRNCLGMRFALMNMKLALTKIMQNFS 465
>CP2F2_MOUSE (P33267) Cytochrome P450 2F2 (EC 1.14.14.-) (CYPIIF2) (Naphthalene| dehydrogenase) (Naphthalene hydroxylase) (P450-NAH-2) Length = 491 Score = 39.7 bits (91), Expect = 0.004 Identities = 20/55 (36%), Positives = 32/55 (58%) Frame = -3 Query: 442 EFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTV 278 EF PE +L +N +F+ F F AG R CLG+ +A +++ S+L+ FT+ Sbjct: 407 EFNPEHFLDDNHSFKKSPAFM--PFSAGRRLCLGEPLARMELFIYFTSILQNFTL 459
>CP17A_PAPHU (Q9GLD2) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 508 Score = 39.7 bits (91), Expect = 0.004 Identities = 20/57 (35%), Positives = 32/57 (56%) Frame = -3 Query: 442 EFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTVDV 272 +F PER+L G Y F AGPR+C+G+ +A ++ I A +L+ F ++V Sbjct: 411 QFMPERFLNPAGTQLISPSLSYLPFGAGPRSCIGEILARQELFLIMAWLLQRFDLEV 467
>CP17A_PAPCY (Q8HYN0) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 508 Score = 39.7 bits (91), Expect = 0.004 Identities = 20/57 (35%), Positives = 32/57 (56%) Frame = -3 Query: 442 EFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTVDV 272 +F PER+L G Y F AGPR+C+G+ +A ++ I A +L+ F ++V Sbjct: 411 QFMPERFLNPAGTQLISPSLSYLPFGAGPRSCIGEILARQELFLIMAWLLQRFDLEV 467
>CP17A_MACMU (Q8HYM9) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 508 Score = 39.7 bits (91), Expect = 0.004 Identities = 20/57 (35%), Positives = 32/57 (56%) Frame = -3 Query: 442 EFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTVDV 272 +F PER+L G Y F AGPR+C+G+ +A ++ I A +L+ F ++V Sbjct: 411 QFMPERFLNPAGTQLISPSLSYLPFGAGPRSCIGEILARQELFLIMAWLLQRFDLEV 467
>CP17A_MACFA (Q2XVA1) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 508 Score = 39.7 bits (91), Expect = 0.004 Identities = 20/57 (35%), Positives = 32/57 (56%) Frame = -3 Query: 442 EFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTVDV 272 +F PER+L G Y F AGPR+C+G+ +A ++ I A +L+ F ++V Sbjct: 411 QFMPERFLNPAGTQLISPSLSYLPFGAGPRSCIGEILARQELFLIMAWLLQRFDLEV 467
>CP17A_HORSE (Q95328) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 508 Score = 39.7 bits (91), Expect = 0.004 Identities = 24/86 (27%), Positives = 41/86 (47%) Frame = -3 Query: 439 FKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTVDVVRKN 260 F PER+L G+ Y F AGPR+C+G+ +A ++ A +L+ F ++V Sbjct: 412 FMPERFLDPTGSQLISPSLSYLPFGAGPRSCIGELLARQELFLFTAWLLQRFNLEVPDDG 471 Query: 259 AGSSAPEHVLSVTLRMKGGLPVQIRR 182 S H +V L + + +R+ Sbjct: 472 QLPSLEGHPTAVFLIDSFKVKINVRQ 497
>CP17A_CHICK (P12394) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 508 Score = 39.7 bits (91), Expect = 0.004 Identities = 31/98 (31%), Positives = 48/98 (48%), Gaps = 1/98 (1%) Frame = -3 Query: 460 WGKDCAEFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFT 281 W K EF P R+L E G Y F AG R CLG+ +A +++ A VL+ FT Sbjct: 409 WDKP-EEFNPGRFLDEQGQHIHSPSPSYLPFGAGIRVCLGEVLAKMELFLFLAWVLQRFT 467 Query: 280 VDVVRKNAGSSAPEHVLSVTLRMKGGLPVQIRR-RVEA 170 ++ P+ +L K G+ +Q+++ RV+A Sbjct: 468 LE---------CPQDQPLPSLEGKFGVVLQVQKFRVKA 496
>CP24A_MOUSE (Q64441) Cytochrome P450 24A1, mitochondrial precursor (EC| 1.14.-.-) (P450-CC24) (Vitamin D(3) 24-hydroxylase) (1,25-dihydroxyvitamin D(3) 24-hydroxylase) (24-OHase) Length = 514 Score = 39.7 bits (91), Expect = 0.004 Identities = 16/59 (27%), Positives = 34/59 (57%) Frame = -3 Query: 454 KDCAEFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTV 278 +D +F+PERWL + + +PF + F G R C+G+ +A +Q+ +++++ + Sbjct: 430 EDADKFRPERWLEKE---KKINPFAHLPFGVGKRMCIGRRLAELQLHLALCWIIQKYNI 485
>CP17A_ICTPU (O73853) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 514 Score = 39.7 bits (91), Expect = 0.004 Identities = 20/56 (35%), Positives = 31/56 (55%) Frame = -3 Query: 439 FKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTVDV 272 F PER+L E G Y F AG R CLG+ +A +++ + +L+ FT++V Sbjct: 415 FNPERFLNEEGNSLCCPSLSYLPFGAGVRVCLGEALAKLELFLFLSWILQRFTLEV 470
>CP11A_ONCMY (Q07217) Cytochrome P450 11A1, mitochondrial precursor (EC| 1.14.15.6) (CYPXIA1) (P450(SCC)) (Cholesterol side-chain cleavage enzyme) (Cholesterol desmolase) Length = 514 Score = 39.7 bits (91), Expect = 0.004 Identities = 24/71 (33%), Positives = 34/71 (47%) Frame = -3 Query: 442 EFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTVDVVRK 263 ++ P RWL + FR F GPR CLG+ +A +M+ +LE F VD R+ Sbjct: 432 KYLPSRWLRTENQY-----FRSLGFGFGPRQCLGRRIAETEMQLFLIHMLENFRVDKQRQ 486 Query: 262 NAGSSAPEHVL 230 S E +L Sbjct: 487 VEVHSTFELIL 497
>CP306_DROME (Q9VWR5) Cytochrome P450 306a1 (EC 1.14.-.-) (CYPCCCVIA1) (Phantom| protein) (Dmphm) Length = 574 Score = 39.7 bits (91), Expect = 0.004 Identities = 22/74 (29%), Positives = 41/74 (55%) Frame = -3 Query: 442 EFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTVDVVRK 263 EF+PER+L +GA+ ++P ++ F +G R C G+EMA + + +L F +++ Sbjct: 476 EFRPERFLTADGAY--QAPPQFIPFSSGYRMCPGEEMARMILTLFTGRILRRFHLELPSG 533 Query: 262 NAGSSAPEHVLSVT 221 A E +++T Sbjct: 534 TEVDMAGESGITLT 547
>C19AA_BRARE (O42145) Cytochrome P450 19A1a (EC 1.14.14.1) (Aromatase) (CYPXIX)| (Estrogen synthetase) (P-450AROM) Length = 509 Score = 39.7 bits (91), Expect = 0.004 Identities = 22/54 (40%), Positives = 33/54 (61%), Gaps = 1/54 (1%) Frame = -3 Query: 436 KPERWLGENGAFRPESPFRY-TVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTV 278 KP ++ +N F P R+ F +GPR+C+GK +A V MKSI ++L F+V Sbjct: 428 KPNQFSLDN--FHKNVPSRFFQPFGSGPRSCVGKHIAMVMMKSILVALLSRFSV 479
>CP2E1_MACMU (Q6GUQ4) Cytochrome P450 2E1 (EC 1.14.14.1) (CYPIIE1)| Length = 493 Score = 39.7 bits (91), Expect = 0.004 Identities = 19/58 (32%), Positives = 35/58 (60%) Frame = -3 Query: 451 DCAEFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTV 278 D +FKPE +L E+G F+ F+ F AG R C G+ +A +++ + +++L+ F + Sbjct: 405 DPEKFKPEHFLDESGKFKYSDYFK--PFSAGKRVCAGEGLARMELFLLLSAILQHFNL 460
>C11B2_MOUSE (P15539) Cytochrome P450 11B2, mitochondrial precursor (EC| 1.14.15.4) (EC 1.14.15.5) (CYPXIB2) (P450C11) (Steroid 11-beta-hydroxylase) (Aldosterone synthase) Length = 500 Score = 39.7 bits (91), Expect = 0.004 Identities = 25/77 (32%), Positives = 42/77 (54%), Gaps = 1/77 (1%) Frame = -3 Query: 457 GKDCAEF-KPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFT 281 G++ A F +PER++ + R S F++ F G R CLG+ +A V+M + +L+ F Sbjct: 411 GRNPAVFPRPERYMPQRWLERKRS-FQHLAFGFGVRQCLGRRLAEVEMMLLLHHILKTFQ 469 Query: 280 VDVVRKNAGSSAPEHVL 230 V+ +R+ A VL Sbjct: 470 VETLRQEDVQMAYRFVL 486
>CP3AC_CANFA (P24463) Cytochrome P450 3A12 (EC 1.14.14.1) (CYPIIIA12)| (P450-PBD-1) Length = 503 Score = 39.7 bits (91), Expect = 0.004 Identities = 20/54 (37%), Positives = 29/54 (53%) Frame = -3 Query: 442 EFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFT 281 EF+PER+ +N +P+ Y F GPR C+G A + MK VL+ F+ Sbjct: 413 EFRPERFSRKNKD--SINPYTYLPFGTGPRNCIGMRFAIMNMKLALVRVLQNFS 464
>CP19A_HORSE (O46512) Cytochrome P450 19A1 (EC 1.14.14.1) (Aromatase) (CYPXIX)| (Estrogen synthetase) (P-450AROM) (P450 17-alpha) Length = 503 Score = 39.7 bits (91), Expect = 0.004 Identities = 24/60 (40%), Positives = 32/60 (53%), Gaps = 1/60 (1%) Frame = -3 Query: 436 KPERWLGENGAFRPESPFRY-TVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTVDVVRKN 260 KP + EN F P+RY F GPR+C GK +A V MK + S+L F V ++ N Sbjct: 409 KPNEFTLEN--FEKNVPYRYFQPFGFGPRSCAGKFIAMVMMKVMLVSLLRRFHVKTLQGN 466
>CP3A7_HUMAN (P24462) Cytochrome P450 3A7 (EC 1.14.14.1) (CYPIIIA7) (P450-HFLA)| Length = 503 Score = 39.3 bits (90), Expect = 0.005 Identities = 20/55 (36%), Positives = 31/55 (56%), Gaps = 3/55 (5%) Frame = -3 Query: 436 KPERWLGENGAFRPES---PFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFT 281 +PE++L E + + + P+ YT F +GPR C+G A V MK VL+ F+ Sbjct: 410 EPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALVNMKLALVRVLQNFS 464
>CP134_DROME (Q9VG40) Probable cytochrome P450 313a4 (EC 1.14.-.-)| (CYPCCCXIIIA4) Length = 478 Score = 39.3 bits (90), Expect = 0.005 Identities = 19/60 (31%), Positives = 28/60 (46%) Frame = -3 Query: 463 IWGKDCAEFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEF 284 IWG D F P+ +L N + + P+ Y F G R C+G A + K A +L + Sbjct: 388 IWGPDAETFNPDHFLPHN--IQDKHPYAYIPFTKGIRNCIGWRYALISAKVTLAKLLRNY 445
>C12A2_MUSDO (O18635) Cytochrome P450 CYP12A2 (EC 1.14.-.-) (CYPXIIA2)| Length = 537 Score = 39.3 bits (90), Expect = 0.005 Identities = 21/67 (31%), Positives = 35/67 (52%), Gaps = 10/67 (14%) Frame = -3 Query: 445 AEFKPERWLGENG----------AFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASV 296 +EF PERWL + A + SPF Y F G R+C+G+ +A ++++ A + Sbjct: 441 SEFLPERWLRASKENEKSAECPHALKASSPFVYLPFGFGSRSCIGRRIAEMELELGIARL 500 Query: 295 LEEFTVD 275 + F V+ Sbjct: 501 IRNFHVE 507
>CP17A_PANTR (Q8HYN1) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 508 Score = 39.3 bits (90), Expect = 0.005 Identities = 20/57 (35%), Positives = 32/57 (56%) Frame = -3 Query: 442 EFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTVDV 272 +F PER+L G Y F AGPR+C+G+ +A ++ I A +L+ F ++V Sbjct: 411 QFMPERFLNPAGTQLISPSVSYLPFGAGPRSCIGEILARQELFLIMAWLLQRFDLEV 467
>CP17A_HUMAN (P05093) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-monooxygenase) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 508 Score = 39.3 bits (90), Expect = 0.005 Identities = 20/57 (35%), Positives = 32/57 (56%) Frame = -3 Query: 442 EFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTVDV 272 +F PER+L G Y F AGPR+C+G+ +A ++ I A +L+ F ++V Sbjct: 411 QFMPERFLNPAGTQLISPSVSYLPFGAGPRSCIGEILARQELFLIMAWLLQRFDLEV 467
>CP17A_CAVPO (Q64410) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 508 Score = 39.3 bits (90), Expect = 0.005 Identities = 20/57 (35%), Positives = 34/57 (59%) Frame = -3 Query: 442 EFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTVDV 272 +F PER+L G+ Y F AGPR+C+G+ +A ++ I A +L++F ++V Sbjct: 411 QFMPERFLDPTGSQIIVPSSSYLPFGAGPRSCVGEALARQEIFLITAWLLQKFDLEV 467
>THAS_MOUSE (P36423) Thromboxane-A synthase (EC 5.3.99.5) (TXA synthase) (TXS)| (TS) Length = 533 Score = 39.3 bits (90), Expect = 0.005 Identities = 26/80 (32%), Positives = 37/80 (46%) Frame = -3 Query: 439 FKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTVDVVRKN 260 F PER+ E A PF Y F AGPR+CLG + + +K VL +F + Sbjct: 451 FDPERFTAE--ARLQRRPFTYLPFGAGPRSCLGVRLGLLVVKLTILQVLHKFRFE----- 503 Query: 259 AGSSAPEHVLSVTLRMKGGL 200 ++PE + + L K L Sbjct: 504 ---ASPETQVPLQLESKSAL 520
>CP9E2_BLAGE (Q964T2) Cytochrome P450 9e2 (EC 1.14.-.-) (CYPIXE2)| Length = 533 Score = 39.3 bits (90), Expect = 0.005 Identities = 22/60 (36%), Positives = 30/60 (50%) Frame = -3 Query: 442 EFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTVDVVRK 263 +F PER+ EN PF Y F +GPR C+G A ++ K +L F + VV K Sbjct: 446 KFDPERFSDENKD--NIKPFTYLPFGSGPRNCIGNRFALMESKIALVHLLCRFNLKVVSK 503
>CP17A_PERLE (Q91Z85) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 509 Score = 39.3 bits (90), Expect = 0.005 Identities = 20/56 (35%), Positives = 29/56 (51%) Frame = -3 Query: 439 FKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTVDV 272 F PER+L G+ Y F AGPR C+G+ +A + A +L+ F +DV Sbjct: 410 FMPERFLDATGSHLITPSLSYLPFGAGPRACIGEVLARQVLFLYVACLLQRFDLDV 465
>C71AI_ARATH (Q9SAB6) Cytochrome P450 71A18 (EC 1.14.-.-)| Length = 497 Score = 39.3 bits (90), Expect = 0.005 Identities = 29/97 (29%), Positives = 42/97 (43%), Gaps = 19/97 (19%) Frame = -3 Query: 466 AIWGKDCAEFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVL-- 293 AIWG D EFKPER L + + +Y F +G R C G +A ++ A+++ Sbjct: 401 AIWGPDAEEFKPERHLDSTLDYHGQD-LKYIPFGSGRRICPGINLAMGLVEVTLANLVGR 459 Query: 292 -----------------EEFTVDVVRKNAGSSAPEHV 233 E+F +DV RKN + P V Sbjct: 460 FDWSVDPGPNGDQPDLAEDFGLDVCRKNPLIAFPSSV 496
>C71AG_ARATH (Q9FH66) Cytochrome P450 71A16 (EC 1.14.-.-)| Length = 497 Score = 39.3 bits (90), Expect = 0.005 Identities = 25/78 (32%), Positives = 35/78 (44%) Frame = -3 Query: 466 AIWGKDCAEFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEE 287 A WG D EF+PER F + F+Y F AG R C G + V A++++ Sbjct: 401 ATWGSDAQEFRPERHFDSTWDFVGRN-FKYIPFGAGRRLCPGIGLGSVMASVTLANLVKR 459 Query: 286 FTVDVVRKNAGSSAPEHV 233 F V +G P+ V Sbjct: 460 FDWRVEDGPSGYDKPDLV 477
>CPXB_BACME (P14779) Bifunctional P-450:NADPH-P450 reductase (Cytochrome| P450(BM-3)) (P450BM-3) [Includes: Cytochrome P450 102 (EC 1.14.14.1); NADPH--cytochrome P450 reductase (EC 1.6.2.4)] Length = 1048 Score = 39.3 bits (90), Expect = 0.005 Identities = 21/60 (35%), Positives = 33/60 (55%) Frame = -3 Query: 463 IWGKDCAEFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEF 284 IWG D EF+PER+ EN + P+ F+ F G R C+G++ A + + +L+ F Sbjct: 366 IWGDDVEEFRPERF--ENPSAIPQHAFK--PFGNGQRACIGQQFALHEATLVLGMMLKHF 421
>CP19A_ORYLA (Q92087) Cytochrome P450 19A1 (EC 1.14.14.1) (Aromatase) (CYPXIX)| (Estrogen synthetase) (P-450AROM) Length = 518 Score = 39.3 bits (90), Expect = 0.005 Identities = 18/43 (41%), Positives = 29/43 (67%), Gaps = 1/43 (2%) Frame = -3 Query: 403 FRPESPFRY-TVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTV 278 F+ +P RY F +GPR C+G+ +A V MKSI ++L +++V Sbjct: 427 FQKNTPRRYFQPFGSGPRACVGRHIAMVMMKSILVTLLSQYSV 469
>C12A4_DROME (Q9VE00) Probable cytochrome P450 12a4, mitochondrial precursor (EC| 1.14.-.-) (CYPXIIA4) Length = 536 Score = 39.3 bits (90), Expect = 0.005 Identities = 25/90 (27%), Positives = 44/90 (48%), Gaps = 11/90 (12%) Frame = -3 Query: 445 AEFKPERWLGEN---------GAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVL 293 +EF PERWL + +PF + F GPR C+GK + ++++ A ++ Sbjct: 441 SEFLPERWLRSPKDSESKCPANELKSTNPFVFLPFGFGPRMCVGKRIVEMELELGTARLI 500 Query: 292 EEFTVD--VVRKNAGSSAPEHVLSVTLRMK 209 F V+ +NA SA ++ ++ L+ K Sbjct: 501 RNFNVEFNYPTENAFRSALINLPNIPLKFK 530
>STCS_EMENI (Q00714) Probable sterigmatocystin biosynthesis P450 monooxygenase| stcS (EC 1.14.-.-) (Cytochrome P450 59) Length = 505 Score = 39.3 bits (90), Expect = 0.005 Identities = 22/66 (33%), Positives = 36/66 (54%), Gaps = 2/66 (3%) Frame = -3 Query: 469 AAIWGKDCAEFKPERWLGENGAFRPESPFR--YTVFHAGPRTCLGKEMAYVQMKSIAASV 296 +A W + F PERWL G+ P P + + F GPR+C+G+ +A ++++ A Sbjct: 395 SAHWA-EAESFIPERWLV--GSDHPLYPAKGAWRAFEFGPRSCIGQTLAMLELRVALAMT 451 Query: 295 LEEFTV 278 L EF + Sbjct: 452 LREFDI 457
>C71AP_ARATH (Q9STK8) Cytochrome P450 71A25 (EC 1.14.-.-)| Length = 490 Score = 39.3 bits (90), Expect = 0.005 Identities = 23/61 (37%), Positives = 31/61 (50%) Frame = -3 Query: 466 AIWGKDCAEFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEE 287 A WG D EFKPER L + FR ++ F F AG R C A V + + A+++ Sbjct: 393 ATWGPDAEEFKPERHLDTSVDFRGQN-FELLPFGAGRRICPAVSFAVVLNEVVLANLVHG 451 Query: 286 F 284 F Sbjct: 452 F 452
>CP4S3_DROME (Q9VXY0) Probable cytochrome P450 4s3 (EC 1.14.-.-) (CYPIVS3)| Length = 495 Score = 39.3 bits (90), Expect = 0.005 Identities = 18/56 (32%), Positives = 31/56 (55%) Frame = -3 Query: 451 DCAEFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEF 284 D F P+R+L + PF + F AGPR C+G++ A +++K+ A +L + Sbjct: 405 DPERFDPDRFLVNE---KQMHPFAFAAFSAGPRNCIGQKFAMLELKTSLAMLLRSY 457
>CP4F3_HUMAN (Q08477) Cytochrome P450 4F3 (EC 1.14.13.30) (CYPIVF3)| (Leukotriene-B(4) omega-hydroxylase) (Leukotriene-B(4) 20-monooxygenase) (Cytochrome P450-LTB-omega) Length = 520 Score = 39.3 bits (90), Expect = 0.005 Identities = 27/93 (29%), Positives = 43/93 (46%) Frame = -3 Query: 466 AIWGKDCAEFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEE 287 A+W D + P R+ +N + SP + F AGPR C+G+ A +MK + L Sbjct: 432 AVW-PDPEVYDPFRFDPKN--IKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLGLTLLR 488 Query: 286 FTVDVVRKNAGSSAPEHVLSVTLRMKGGLPVQI 188 F R + P + LR +GGL +++ Sbjct: 489 F-----RVLPDHTEPRRKPELVLRAEGGLWLRV 516
>CP3A2_RAT (P05183) Cytochrome P450 3A2 (EC 1.14.14.1) (CYPIIIA2) (P450-PCN2)| (P450/6-beta-A) (Testosterone 6-beta-hydroxylase) Length = 504 Score = 39.3 bits (90), Expect = 0.005 Identities = 21/54 (38%), Positives = 27/54 (50%) Frame = -3 Query: 442 EFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFT 281 EF PER+ EN P+ Y F GPR C+G A + MK VL+ F+ Sbjct: 414 EFHPERFSKENKG--SIDPYVYLPFGNGPRNCIGMRFALMNMKLALTKVLQNFS 465
>CP11A_HORSE (O46515) Cytochrome P450 11A1, mitochondrial precursor (EC| 1.14.15.6) (CYPXIA1) (P450(scc)) (Cholesterol side-chain cleavage enzyme) (Cholesterol desmolase) Length = 520 Score = 38.9 bits (89), Expect = 0.007 Identities = 26/79 (32%), Positives = 37/79 (46%), Gaps = 6/79 (7%) Frame = -3 Query: 439 FKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTVDVVRKN 260 F P RWL +N + + FR F G R CLG+ +A ++M +LE F V++ N Sbjct: 434 FDPTRWLDKN---KDLTHFRNLGFGWGVRQCLGRRIAELEMTLFLIHILENFRVEIQHLN 490 Query: 259 AGSSA------PEHVLSVT 221 S PE +S T Sbjct: 491 DVDSTFGLILIPEKPISFT 509
>C356_FUNHE (Q8AXY5) Cytochrome P450 3A56 (EC 1.14.14.1) (CYPIIIA56)| Length = 496 Score = 38.9 bits (89), Expect = 0.007 Identities = 22/67 (32%), Positives = 36/67 (53%) Frame = -3 Query: 463 IWGKDCAEFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEF 284 IW + A FKPER+ +N P+ Y F +GPR C+G A V +K +L+++ Sbjct: 406 IWPEPEA-FKPERFSKKNKD--NIDPYIYMPFGSGPRNCIGMRFALVLIKLAVVEILQQY 462 Query: 283 TVDVVRK 263 + V ++ Sbjct: 463 SFSVCKE 469
>C330_FUNHE (Q9PVE8) Cytochrome P450 3A30 (EC 1.14.14.1) (CYPIIIA30)| Length = 496 Score = 38.9 bits (89), Expect = 0.007 Identities = 22/67 (32%), Positives = 36/67 (53%) Frame = -3 Query: 463 IWGKDCAEFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEF 284 IW + A FKPER+ +N P+ Y F +GPR C+G A V +K +L+++ Sbjct: 406 IWPEPEA-FKPERFSKKNKD--NIDPYIYMPFGSGPRNCIGMRFALVLIKLAVVEILQQY 462 Query: 283 TVDVVRK 263 + V ++ Sbjct: 463 SFSVCKE 469
>CP52G_CANTR (P30609) Cytochrome P450 52A7 (EC 1.14.14.-) (CYPLIIA7)| (Alkane-inducible P450-ALK4) Length = 507 Score = 38.9 bits (89), Expect = 0.007 Identities = 19/59 (32%), Positives = 29/59 (49%) Frame = -3 Query: 460 WGKDCAEFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEF 284 +GKD F+PERW + + Y F+ GPR CLG++ A + I + + F Sbjct: 422 YGKDAKLFRPERWFESSTR---NLGWAYLPFNGGPRICLGQQFALTEAGYILVRLAQSF 477
>CP17A_MOUSE (P27786) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 507 Score = 38.9 bits (89), Expect = 0.007 Identities = 20/56 (35%), Positives = 30/56 (53%) Frame = -3 Query: 439 FKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTVDV 272 F PER+L G+ Y F AGPR+C+G+ +A ++ A +L+ F DV Sbjct: 411 FMPERFLDPTGSHLITPTPSYLPFGAGPRSCIGEALARQELFIFMALLLQRFDFDV 466
>CP2F2_RAT (O35293) Cytochrome P450 2F2 (EC 1.14.14.-) (CYPIIF2) (Naphthalene| dehydrogenase) (Naphthalene hydroxylase) (P450-NAH-2) Length = 491 Score = 38.9 bits (89), Expect = 0.007 Identities = 20/55 (36%), Positives = 31/55 (56%) Frame = -3 Query: 442 EFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTV 278 EF PE +L N +F+ F F AG R CLG+ +A +++ S+L+ FT+ Sbjct: 407 EFNPEHFLDANQSFKKSPAFM--PFSAGRRLCLGEPLARMELFIYLTSILQNFTL 459
>CP24A_RAT (Q09128) Cytochrome P450 24A1, mitochondrial precursor (EC| 1.14.-.-) (P450-CC24) (Vitamin D(3) 24-hydroxylase) (1,25-dihydroxyvitamin D(3) 24-hydroxylase) (24-OHase) Length = 514 Score = 38.9 bits (89), Expect = 0.007 Identities = 25/93 (26%), Positives = 49/93 (52%), Gaps = 1/93 (1%) Frame = -3 Query: 454 KDCAEFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTVD 275 +D +F+PERWL + + +PF + F G R C+G+ +A +Q+ +++++ D Sbjct: 430 EDSHKFRPERWLQKE---KKINPFAHLPFGIGKRMCIGRRLAELQLHLALCWIIQKY--D 484 Query: 274 VVRKNAGSSAPEHVLSVTLRMKG-GLPVQIRRR 179 +V A + P +L + + + LP+ R R Sbjct: 485 IV---ATDNEPVEMLHLGILVPSRELPIAFRPR 514
>CP4F1_RAT (P33274) Cytochrome P450 4F1 (EC 1.14.14.1) (CYPIVF1) (P450-A3)| Length = 524 Score = 38.9 bits (89), Expect = 0.007 Identities = 28/93 (30%), Positives = 42/93 (45%) Frame = -3 Query: 466 AIWGKDCAEFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEE 287 ++W D + P R+ EN + SP + F AGPR C+G+ A +MK A L Sbjct: 432 SVW-PDPEVYNPFRFDPEN--IKDSSPLAFIPFSAGPRNCIGQTFAMSEMKVALALTLLR 488 Query: 286 FTVDVVRKNAGSSAPEHVLSVTLRMKGGLPVQI 188 F R P + LR +GGL +++ Sbjct: 489 F-----RLLPDDKEPRRQPELILRAEGGLWLRV 516
>CP52P_CANTR (P30612) Cytochrome P450 52C1 (EC 1.14.14.-) (CYPLIIC1)| (Alkane-inducible P450-ALK7) Length = 505 Score = 38.9 bits (89), Expect = 0.007 Identities = 25/89 (28%), Positives = 42/89 (47%) Frame = -3 Query: 460 WGKDCAEFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFT 281 +G + +F PERW R E + F AGPR CLG+++ V+ + +L+ F Sbjct: 422 FGTNTDKFAPERW--SESLRRTE----FIPFSAGPRACLGQQLPRVEASYVTIRLLQTF- 474 Query: 280 VDVVRKNAGSSAPEHVLSVTLRMKGGLPV 194 + + P V++ T+R+ G V Sbjct: 475 -HGLHNASKQYPPNRVVAATMRLTDGCNV 502
>CP3AO_SHEEP (Q29496) Cytochrome P450 3A24 (EC 1.14.14.1) (CYPIIIA24)| Length = 503 Score = 38.9 bits (89), Expect = 0.007 Identities = 20/54 (37%), Positives = 29/54 (53%) Frame = -3 Query: 442 EFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFT 281 EF+PER+ +N +P+ Y F GPR C+G A + MK VL+ F+ Sbjct: 413 EFRPERFSKKNKD--SINPYVYLPFGTGPRNCIGMRFAIMNMKLAIVRVLQNFS 464
>C11B1_BOVIN (P15150) Cytochrome P450 11B1, mitochondrial precursor (EC| 1.14.15.4) (CYPXIB1) (P450C11) (Steroid 11-beta-hydroxylase) Length = 503 Score = 38.9 bits (89), Expect = 0.007 Identities = 20/59 (33%), Positives = 32/59 (54%) Frame = -3 Query: 439 FKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTVDVVRK 263 + P+RWL G+ S F + F G R CLG+ +A V+M + VL+ F V+ + + Sbjct: 423 YHPQRWLDRQGS---GSRFPHLAFGFGVRQCLGRRVAEVEMLLLLHHVLKNFLVETLEQ 478
>CP270_RAT (P19225) Cytochrome P450 2C70 (EC 1.14.14.1) (CYPIIC70) (P-450Md)| (P450 P49) Length = 489 Score = 38.9 bits (89), Expect = 0.007 Identities = 20/55 (36%), Positives = 31/55 (56%) Frame = -3 Query: 442 EFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTV 278 +F P +L E G F+ F F AG R C+G+ +A ++M I S+L+ FT+ Sbjct: 405 KFDPGHFLDEKGNFKKSDYFM--AFSAGRRACIGEGLARMEMFLILTSILQHFTL 457
>C11B3_RAT (P30100) Cytochrome P450 11B3, mitochondrial precursor (EC| 1.14.15.4) (EC 1.14.15.5) (CYPXIB3) (P450-Aldo-2) (Aldosterone synthase) Length = 500 Score = 38.5 bits (88), Expect = 0.009 Identities = 25/77 (32%), Positives = 42/77 (54%), Gaps = 1/77 (1%) Frame = -3 Query: 457 GKDCAEF-KPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFT 281 G++ A F +PER++ + R S F++ F G R CLG+ +A V+M + +L+ F Sbjct: 411 GRNPAVFPRPERYMPQRWLERKRS-FQHLAFGFGVRQCLGRRLAEVEMLLLLHHMLKTFQ 469 Query: 280 VDVVRKNAGSSAPEHVL 230 V+ +R+ A VL Sbjct: 470 VETLRQEDVQMAYRFVL 486
>CP3AF_CAVPO (Q64406) Cytochrome P450 3A15 (EC 1.14.14.1) (CYPIIIA15)| Length = 503 Score = 38.5 bits (88), Expect = 0.009 Identities = 19/54 (35%), Positives = 30/54 (55%) Frame = -3 Query: 442 EFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFT 281 EF+PER+ +N P+ Y F GPR C+G+ MA + +K +L+ F+ Sbjct: 413 EFRPERFSKKNK--ENIDPYIYMPFGNGPRNCIGRRMALMNLKLALIRLLQNFS 464
>C11B1_SHEEP (P51663) Cytochrome P450 11B1, mitochondrial precursor (EC| 1.14.15.4) (CYPXIB1) (P450C11) (Steroid 11-beta-hydroxylase) Length = 503 Score = 38.5 bits (88), Expect = 0.009 Identities = 20/57 (35%), Positives = 31/57 (54%) Frame = -3 Query: 439 FKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTVDVV 269 + P+RWL G+ S F + F G R CLG+ +A V+M + VL+ F V+ + Sbjct: 423 YHPQRWLDRQGS---GSRFPHLAFGFGMRQCLGRRVAEVEMLLLLHHVLKNFLVETL 476
>CP2CV_CAPAE (Q29478) Cytochrome P450 2C31 (EC 1.14.14.1) (CYPIIC31) (Fragment)| Length = 284 Score = 38.5 bits (88), Expect = 0.009 Identities = 19/58 (32%), Positives = 33/58 (56%) Frame = -3 Query: 442 EFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTVDVV 269 +F P +L E+G F+ F F AG R C+G+ +A +++ + S+L+ FT+ V Sbjct: 200 QFDPAHFLDESGNFKKTDHFM--AFSAGKRVCVGEGLARMELFLLLVSILQHFTLKPV 255
>CP4FE_MOUSE (Q9EP75) Cytochrome P450 4F14 (EC 1.14.13.30) (Leukotriene-B4| omega-hydroxylase) (Leukotriene-B4 20-monooxygenase) (Cytochrome P450-LTB-omega) (Cyp4f-14) Length = 524 Score = 38.5 bits (88), Expect = 0.009 Identities = 28/93 (30%), Positives = 42/93 (45%) Frame = -3 Query: 466 AIWGKDCAEFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEE 287 ++W D + P R+ EN + SP + F AGPR C+G+ A +MK A L Sbjct: 432 SVW-PDPEVYDPFRFDPEN--IKDSSPLAFIPFSAGPRNCIGQTFAMSEMKVALALTLLR 488 Query: 286 FTVDVVRKNAGSSAPEHVLSVTLRMKGGLPVQI 188 F R P + LR +GGL +++ Sbjct: 489 F-----RLLPDDKEPRRQPELILRAEGGLWLRV 516
>CP17A_RANDY (O57525) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 519 Score = 38.5 bits (88), Expect = 0.009 Identities = 27/87 (31%), Positives = 45/87 (51%), Gaps = 2/87 (2%) Frame = -3 Query: 439 FKPERWLGENG--AFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTVDVVR 266 F P+R+L ENG + P F F AG R CLG+ +A +++ + +L+ FT++V Sbjct: 425 FSPDRFLDENGNRVYSPSPSF--LPFGAGIRVCLGEALAKMEVFLFLSWILQRFTLEVPE 482 Query: 265 KNAGSSAPEHVLSVTLRMKGGLPVQIR 185 G P+ L K G+ +Q++ Sbjct: 483 ---GDPLPD------LEGKFGVVIQVK 500
>CP4G1_DROME (Q9V3S0) Cytochrome P450 4g1 (EC 1.14.-.-) (CYPIVG1)| Length = 556 Score = 38.5 bits (88), Expect = 0.009 Identities = 21/88 (23%), Positives = 46/88 (52%) Frame = -3 Query: 442 EFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTVDVVRK 263 +F P+ +L E A R + + F AGPR+C+G++ A +++K + ++++ + V Sbjct: 468 KFDPDNFLPERMANRHY--YSFIPFSAGPRSCVGRKYAMLKLKVLLSTIVRNYIVHSTDT 525 Query: 262 NAGSSAPEHVLSVTLRMKGGLPVQIRRR 179 A ++ L+++ G V + +R Sbjct: 526 EADFKLQADII---LKLENGFNVSLEKR 550
>CP6V1_DROME (Q9VRB3) Probable cytochrome P450 6v1 (EC 1.14.-.-) (CYPVIV1)| Length = 520 Score = 38.5 bits (88), Expect = 0.009 Identities = 20/60 (33%), Positives = 31/60 (51%) Frame = -3 Query: 451 DCAEFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTVDV 272 D F PER+ N A ++P Y F AGPR C+G ++ +Q+K L + V++ Sbjct: 433 DPDRFDPERFSAANKAL--QAPMSYMPFGAGPRNCIGMQIGLLQIKLGLVYFLHQHRVEI 490
>CP27B_MOUSE (O35084) 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial| precursor (EC 1.14.13.13) (Cytochrome P450 subfamily XXVIIB polypeptide 1) (Cytochrome p450 27B1) (Calcidiol 1-monooxygenase) (25-OHD-1 alpha-hydroxylase) (25-hydroxyvitamin D(3) Length = 507 Score = 38.5 bits (88), Expect = 0.009 Identities = 19/58 (32%), Positives = 29/58 (50%) Frame = -3 Query: 451 DCAEFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTV 278 D F P RWLGE PF F G R+C+G+ +A ++++ + +L F V Sbjct: 423 DPNSFNPARWLGEGPT---PHPFASLPFGFGKRSCIGRRLAELELQMALSQILTHFEV 477
>C11B2_RAT (P30099) Cytochrome P450 11B2, mitochondrial precursor (EC| 1.14.15.4) (EC 1.14.15.5) (CYPXIB2) (P450-Aldo-1) (Aldosterone synthase) Length = 510 Score = 38.5 bits (88), Expect = 0.009 Identities = 25/77 (32%), Positives = 42/77 (54%), Gaps = 1/77 (1%) Frame = -3 Query: 457 GKDCAEF-KPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFT 281 G++ A F +PER++ + R S F++ F G R CLG+ +A V+M + +L+ F Sbjct: 421 GRNPAVFPRPERYMPQRWLERKRS-FQHLAFGFGVRQCLGRRLAEVEMLLLLHHMLKTFQ 479 Query: 280 VDVVRKNAGSSAPEHVL 230 V+ +R+ A VL Sbjct: 480 VETLRQEDVQMAYRFVL 496
>CP52N_CANTR (P30611) Cytochrome P450 52B1 (EC 1.14.14.-) (CYPLIIB1)| (Alkane-inducible P450-ALK6) Length = 506 Score = 38.1 bits (87), Expect = 0.011 Identities = 20/73 (27%), Positives = 35/73 (47%) Frame = -3 Query: 460 WGKDCAEFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFT 281 +G D F+P+RW + +Y F+AGPRTCLG++ ++ + + + T Sbjct: 417 FGSDAHVFRPDRWFDSS---MKNLGCKYLPFNAGPRTCLGQQYTLIEASYLLVRLAQ--T 471 Query: 280 VDVVRKNAGSSAP 242 + V + S P Sbjct: 472 YETVESHPDSVYP 484
>CP51_WHEAT (P93596) Cytochrome P450 51 (EC 1.14.13.70) (CYPLI) (P450-LIA1)| (Obtusifoliol 14-alpha demethylase) (Fragment) Length = 453 Score = 38.1 bits (87), Expect = 0.011 Identities = 26/93 (27%), Positives = 45/93 (48%), Gaps = 1/93 (1%) Frame = -3 Query: 454 KDCAEFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTVD 275 K+ + P+R+ + F Y F G CLG+ AY+Q+K+I +L F + Sbjct: 360 KNPDSYDPDRFAAGREEDKVAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFE 419 Query: 274 VVRKNAGSSAPEHVL-SVTLRMKGGLPVQIRRR 179 +V S PE+ ++ + +KG + V +RR Sbjct: 420 LV-----SPFPENDWNAMVVGIKGEVMVNYKRR 447
>CP191_CARAU (P79690) Cytochrome P450 19 type 1 (EC 1.14.14.1) (Brain aromatase)| (CYPXIXA1) (Estrogen synthetase) (P-450AROM) Length = 510 Score = 38.1 bits (87), Expect = 0.011 Identities = 23/54 (42%), Positives = 29/54 (53%), Gaps = 1/54 (1%) Frame = -3 Query: 436 KPERWLGENGAFRPESPFRY-TVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTV 278 KP + EN F P RY F GPR C+GK +A V K+I ++L FTV Sbjct: 407 KPNEFNLEN--FENTVPSRYFQPFGCGPRACVGKHIAMVMTKAILVTLLSRFTV 458
>CP4CU_BLAGE (Q964T1) Cytochrome P450 4c21 (EC 1.14.14.1) (CYPIVC21)| Length = 501 Score = 38.1 bits (87), Expect = 0.011 Identities = 21/84 (25%), Positives = 40/84 (47%) Frame = -3 Query: 439 FKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTVDVVRKN 260 F P+ +L + R P+ Y F AGPR C+G+ A ++ K + + +L + V K Sbjct: 419 FNPDNFLPDRVVNR--HPYAYIPFSAGPRNCIGQRFALLEEKVVLSYLLRHYRFRTVNKR 476 Query: 259 AGSSAPEHVLSVTLRMKGGLPVQI 188 S +++ ++ P+Q+ Sbjct: 477 EDSKFKLEMINTPVK-----PIQL 495
>CP27A_HUMAN (Q02318) Cytochrome P450 27, mitochondrial precursor (EC| 1.14.13.15) (Cytochrome P-450C27/25) (Sterol 26-hydroxylase) (Sterol 27-hydroxylase) (Vitamin D(3) 25-hydroxylase) (5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol 27-hydroxylase) Length = 531 Score = 38.1 bits (87), Expect = 0.011 Identities = 18/56 (32%), Positives = 32/56 (57%), Gaps = 2/56 (3%) Frame = -3 Query: 439 FKPERWLGENGAFRP--ESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTV 278 F+P RWL + P + PF F G R CLG+ +A ++M+ + A +++++ V Sbjct: 444 FQPHRWLRNSQPATPRIQHPFGSVPFGYGVRACLGRRIAELEMQLLLARLIQKYKV 499
>CP17A_PIG (P19100) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 509 Score = 38.1 bits (87), Expect = 0.011 Identities = 18/56 (32%), Positives = 30/56 (53%) Frame = -3 Query: 439 FKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTVDV 272 F PER+L G Y F AGPR+C+G+ +A ++ A +L+ F +++ Sbjct: 412 FMPERFLDPTGTQLISPSLSYLPFGAGPRSCVGEMLARQELFLFTAGLLQRFDLEL 467
>CP19A_HUMAN (P11511) Cytochrome P450 19A1 (EC 1.14.14.1) (Aromatase) (CYPXIX)| (Estrogen synthetase) (P-450AROM) Length = 502 Score = 38.1 bits (87), Expect = 0.011 Identities = 23/58 (39%), Positives = 31/58 (53%), Gaps = 1/58 (1%) Frame = -3 Query: 436 KPERWLGENGAFRPESPFRY-TVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTVDVVR 266 KP + EN F P+RY F GPR C GK +A V MK+I ++L F V ++ Sbjct: 408 KPNEFTLEN--FAKNVPYRYFQPFGFGPRGCAGKYIAMVMMKAILVTLLRRFHVKTLQ 463
>STCL_EMENI (Q00707) Probable sterigmatocystin biosynthesis P450 monooxygenase| STCL (EC 1.14.-.-) (Cytochrome P450 60B) Length = 500 Score = 38.1 bits (87), Expect = 0.011 Identities = 25/92 (27%), Positives = 46/92 (50%), Gaps = 6/92 (6%) Frame = -3 Query: 442 EFKPERWLGENGAFRPESPFR------YTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFT 281 +F PER L GA + E PFR Y + G R C+G+ +AY +++ A +L F Sbjct: 410 KFIPERHLA--GA-KLEEPFRHDNYAAYQPWSVGVRNCIGRNLAYAEVRLTLAKLLWHFD 466 Query: 280 VDVVRKNAGSSAPEHVLSVTLRMKGGLPVQIR 185 + + + G+ + + S+ + + L ++ R Sbjct: 467 ISLDEERTGNFLDQKIWSIWAKRELYLEIRTR 498
>CP3A8_MACFA (P33268) Cytochrome P450 3A8 (EC 1.14.14.1) (CYPIIIA8) (P450-MKNF2)| (P-450-MK2) Length = 503 Score = 38.1 bits (87), Expect = 0.011 Identities = 20/54 (37%), Positives = 29/54 (53%) Frame = -3 Query: 442 EFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFT 281 +F PER+ +N P+ YT F +GPR C+G A + MK VL+ F+ Sbjct: 413 KFLPERFSKKNND--NIDPYIYTPFGSGPRNCIGMRFALMNMKLAIIRVLQNFS 464
>CP19A_SHEEP (Q9XS28) Cytochrome P450 19A1 (EC 1.14.14.1) (Aromatase) (CYPXIX)| (Estrogen synthetase) (P-450AROM) Length = 503 Score = 38.1 bits (87), Expect = 0.011 Identities = 23/58 (39%), Positives = 30/58 (51%), Gaps = 1/58 (1%) Frame = -3 Query: 436 KPERWLGENGAFRPESPFRY-TVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTVDVVR 266 KP + EN F P+RY F GPR C GK +A V MK I ++L F V ++ Sbjct: 409 KPNEFTLEN--FAKNVPYRYFQPFGFGPRACAGKYIAMVMMKVILVTLLRRFHVQTLQ 464
>CP19A_CAPHI (Q6YI21) Cytochrome P450 19A1 (EC 1.14.14.1) (Aromatase) (CYPXIX)| (Estrogen synthetase) (P-450AROM) Length = 503 Score = 38.1 bits (87), Expect = 0.011 Identities = 23/58 (39%), Positives = 30/58 (51%), Gaps = 1/58 (1%) Frame = -3 Query: 436 KPERWLGENGAFRPESPFRY-TVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTVDVVR 266 KP + EN F P+RY F GPR C GK +A V MK I ++L F V ++ Sbjct: 409 KPNEFTLEN--FAKNVPYRYFQPFGFGPRACAGKYIAMVMMKVILVTLLRRFHVQTLQ 464
>CP19A_CANFA (Q5QQX7) Cytochrome P450 19A1 (EC 1.14.14.1) (Aromatase) (CYPXIX)| (Estrogen synthetase) (P-450AROM) Length = 503 Score = 38.1 bits (87), Expect = 0.011 Identities = 22/58 (37%), Positives = 31/58 (53%), Gaps = 1/58 (1%) Frame = -3 Query: 436 KPERWLGENGAFRPESPFRY-TVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTVDVVR 266 KP + EN F P+RY F GPR+C GK +A V MK + ++L F V ++ Sbjct: 409 KPNEFTLEN--FAKNVPYRYFQPFGFGPRSCAGKYIAMVMMKVVLVTLLRRFHVQTLQ 464
>CP19A_ANGJA (Q6QHT9) Cytochrome P450 19A1 (EC 1.14.14.1) (Aromatase) (CYPXIX)| (Estrogen synthetase) (P-450AROM) Length = 511 Score = 38.1 bits (87), Expect = 0.011 Identities = 21/54 (38%), Positives = 33/54 (61%), Gaps = 1/54 (1%) Frame = -3 Query: 436 KPERWLGENGAFRPESPFRY-TVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTV 278 KP + EN F P R+ F +GPR+C+GK ++ V MK+I A++L +T+ Sbjct: 422 KPNEFSLEN--FEKTVPNRFFQPFGSGPRSCVGKHISMVMMKAILATLLSRYTM 473
>CP17A_MESAU (P70687) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 511 Score = 38.1 bits (87), Expect = 0.011 Identities = 19/56 (33%), Positives = 30/56 (53%) Frame = -3 Query: 439 FKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTVDV 272 F PER+L G+ Y F AG R+C+G+ +A ++ A +L+ F +DV Sbjct: 412 FMPERFLDPTGSHLITPSLSYLPFGAGARSCIGEVLARQELFLFMAHLLQRFDLDV 467
>C11B1_PIG (Q29552) Cytochrome P450 11B1, mitochondrial precursor (EC| 1.14.15.4) (CYPXIB1) (P450C11) (Steroid 11-beta-hydroxylase) Length = 503 Score = 38.1 bits (87), Expect = 0.011 Identities = 19/57 (33%), Positives = 31/57 (54%) Frame = -3 Query: 439 FKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTVDVV 269 + P+RWL G+ + F + F G R CLG+ +A V+M + VL+ F V+ + Sbjct: 423 YHPQRWLDNQGS---GTRFPHLAFGFGMRQCLGRRLAQVEMLLLLHHVLKNFLVETL 476
>CP270_MOUSE (Q91W64) Cytochrome P450 2C70 (EC 1.14.14.1) (CYPIIC70)| Length = 489 Score = 38.1 bits (87), Expect = 0.011 Identities = 19/55 (34%), Positives = 31/55 (56%) Frame = -3 Query: 442 EFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTV 278 +F P +L E G F+ F F AG R C+G+ +A ++M I ++L+ FT+ Sbjct: 405 KFDPGHFLDEKGNFKKSDYF--VAFSAGRRACIGEGLARMEMFLILTNILQHFTL 457
>CP3AV_MESAU (O70537) Cytochrome P450 3A31 (EC 1.14.14.1) (CYPIIIA31) (P450| SH3A-1) Length = 501 Score = 37.7 bits (86), Expect = 0.015 Identities = 19/55 (34%), Positives = 29/55 (52%) Frame = -3 Query: 442 EFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTV 278 +F+PER+ EN P+ + F GPR C+G A + MK VL+ F++ Sbjct: 411 KFRPERFSKENKG--SIDPYIFLPFGNGPRNCIGMRFALMNMKLALTKVLQNFSL 463
>CP193_PIG (P79304) Cytochrome P450 19 type III (EC 1.14.14.1) (Aromatase)| (CYPXIXA3) (Estrogen synthetase) (P-450AROM) Length = 501 Score = 37.7 bits (86), Expect = 0.015 Identities = 23/54 (42%), Positives = 28/54 (51%), Gaps = 1/54 (1%) Frame = -3 Query: 436 KPERWLGENGAFRPESPFRY-TVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTV 278 KP + EN F P+RY F GPR C GK +A V MK I ++L F V Sbjct: 407 KPNEFTLEN--FAKNVPYRYFQPFGFGPRACAGKYIAMVMMKVILVTLLRRFQV 458
>CP4F4_RAT (P51869) Cytochrome P450 4F4 (EC 1.14.14.1) (CYPIVF4)| Length = 522 Score = 37.7 bits (86), Expect = 0.015 Identities = 28/92 (30%), Positives = 41/92 (44%) Frame = -3 Query: 463 IWGKDCAEFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEF 284 +W D + P R+ EN + SP + F AGPR C+G+ A +MK A L F Sbjct: 433 VW-PDPEVYDPFRFDPEN--IKDRSPLAFIPFSAGPRNCIGQTFAMNEMKVALALTLLRF 489 Query: 283 TVDVVRKNAGSSAPEHVLSVTLRMKGGLPVQI 188 R P + LR +GGL +++ Sbjct: 490 -----RVLPDDKEPRRKPELILRAEGGLWLRV 516
>CP17A_BOVIN (P05185) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 509 Score = 37.7 bits (86), Expect = 0.015 Identities = 22/77 (28%), Positives = 38/77 (49%) Frame = -3 Query: 439 FKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTVDVVRKN 260 F PER+L G Y F AGPR+C+G+ +A ++ + +L+ F +++ Sbjct: 412 FMPERFLDPTGTQLISPSLSYLPFGAGPRSCVGEMLARQELFLFMSRLLQRFNLEIPDDG 471 Query: 259 AGSSAPEHVLSVTLRMK 209 S H S+ L++K Sbjct: 472 KLPSLEGHA-SLVLQIK 487
>CP17A_BISBI (Q9GMC7) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 509 Score = 37.7 bits (86), Expect = 0.015 Identities = 22/77 (28%), Positives = 38/77 (49%) Frame = -3 Query: 439 FKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTVDVVRKN 260 F PER+L G Y F AGPR+C+G+ +A ++ + +L+ F +++ Sbjct: 412 FMPERFLDPTGTQLISPSLSYLPFGAGPRSCVGEMLARQELFLFMSRLLQRFNLEIPDDG 471 Query: 259 AGSSAPEHVLSVTLRMK 209 S H S+ L++K Sbjct: 472 KLPSLEGHA-SLVLQIK 487
>CP1A1_FELCA (Q5KQT7) Cytochrome P450 1A1 (EC 1.14.14.1) (CYPIA1)| Length = 517 Score = 37.7 bits (86), Expect = 0.015 Identities = 21/80 (26%), Positives = 41/80 (51%) Frame = -3 Query: 463 IWGKDCAEFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEF 284 +WG D +EF+PER+L +G + +F G R C+G+ +A +++ A +L++ Sbjct: 425 LWG-DPSEFRPERFLTPDGTINKALSEKVILFGLGKRKCIGETIARLEVFLFLAILLQQV 483 Query: 283 TVDVVRKNAGSSAPEHVLSV 224 V + P + L++ Sbjct: 484 EFSVPQGTKVDMTPIYGLTM 503
>C11B1_RAT (P15393) Cytochrome P450 11B1, mitochondrial precursor (EC| 1.14.15.4) (CYPXIB1) (P450C11) (Steroid 11-beta-hydroxylase) (P450(11 beta)-DS) Length = 499 Score = 37.7 bits (86), Expect = 0.015 Identities = 22/66 (33%), Positives = 39/66 (59%), Gaps = 1/66 (1%) Frame = -3 Query: 457 GKDCAEF-KPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFT 281 G++ A F +PER++ + R S F++ F G R CLG+ +A V+M + +L+ F Sbjct: 410 GRNPAVFPRPERYMPQRWLERKRS-FQHLAFGFGVRQCLGRRLAEVEMLLLLHHMLKTFQ 468 Query: 280 VDVVRK 263 V+ +R+ Sbjct: 469 VETLRQ 474
>CP3A4_HUMAN (P08684) Cytochrome P450 3A4 (EC 1.14.13.67) (Quinine| 3-monooxygenase) (CYPIIIA4) (Nifedipine oxidase) (Taurochenodeoxycholate 6-alpha-hydroxylase) (EC 1.14.13.97) (NF-25) (P450-PCN1) Length = 502 Score = 37.7 bits (86), Expect = 0.015 Identities = 19/55 (34%), Positives = 31/55 (56%), Gaps = 3/55 (5%) Frame = -3 Query: 436 KPERWLGENGAFRPES---PFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFT 281 +PE++L E + + + P+ YT F +GPR C+G A + MK VL+ F+ Sbjct: 409 EPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFS 463
>CP317_DROME (Q9V776) Probable cytochrome P450 317a1 (EC 1.14.-.-)| (CYPCCCXVIIA1) Length = 518 Score = 37.7 bits (86), Expect = 0.015 Identities = 18/56 (32%), Positives = 31/56 (55%) Frame = -3 Query: 451 DCAEFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEF 284 D EFKP+RW G + + + + F G R+C+G + A +Q++ A +L E+ Sbjct: 429 DPEEFKPDRWSGPRDSLQEQG--TWFGFGVGARSCIGIQFAQLQLRLALALLLSEY 482
>C97B2_SOYBN (O48921) Cytochrome P450 97B2 (EC 1.14.-.-)| Length = 576 Score = 37.7 bits (86), Expect = 0.015 Identities = 27/108 (25%), Positives = 47/108 (43%), Gaps = 20/108 (18%) Frame = -3 Query: 442 EFKPERWLGEN-----------------GAFRPE---SPFRYTVFHAGPRTCLGKEMAYV 323 +F+PER+L +N GA P S F + F GPR C+G + A + Sbjct: 468 DFEPERFLVQNKNEEIEGWAGLDPSRSPGALYPNEVISDFAFLPFGGGPRKCVGDQFALM 527 Query: 322 QMKSIAASVLEEFTVDVVRKNAGSSAPEHVLSVTLRMKGGLPVQIRRR 179 + +L+ F V++ + E V T+ K G+ ++++R Sbjct: 528 ESTVALTMLLQNFDVEL---KGTPESVELVTGATIHTKNGMWCRLKKR 572
>CP3AT_PIG (P79401) Cytochrome P450 3A29 (EC 1.14.14.1) (CYPIIIA29)| Length = 503 Score = 37.7 bits (86), Expect = 0.015 Identities = 19/54 (35%), Positives = 29/54 (53%) Frame = -3 Query: 442 EFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFT 281 EF+PER+ ++ +P+ Y F GPR C+G A + MK VL+ F+ Sbjct: 413 EFRPERFSKKHKD--TINPYTYLPFGTGPRNCIGMRFALMNMKLALVRVLQNFS 464
>CP3A9_RAT (P51538) Cytochrome P450 3A9 (EC 1.14.14.1) (CYPIIIA9) (P450-OLF3)| (Olfactive) (3AH15) Length = 503 Score = 37.7 bits (86), Expect = 0.015 Identities = 20/54 (37%), Positives = 29/54 (53%) Frame = -3 Query: 442 EFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFT 281 EF+PER+ +N +P+ Y F GPR C+G A + MK VL+ F+ Sbjct: 413 EFRPERFSKKNQD--NINPYMYLPFGNGPRNCIGMRFALMNMKVALFRVLQNFS 464
>CP3A3_HUMAN (P05184) Cytochrome P450 3A3 (EC 1.14.14.1) (CYPIIIA3) (HLp)| Length = 503 Score = 37.7 bits (86), Expect = 0.015 Identities = 19/55 (34%), Positives = 31/55 (56%), Gaps = 3/55 (5%) Frame = -3 Query: 436 KPERWLGENGAFRPES---PFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFT 281 +PE++L E + + + P+ YT F +GPR C+G A + MK VL+ F+ Sbjct: 410 EPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFS 464
>C71AQ_ARATH (Q9STK7) Cytochrome P450 71A26 (EC 1.14.-.-)| Length = 489 Score = 37.7 bits (86), Expect = 0.015 Identities = 21/62 (33%), Positives = 32/62 (51%) Frame = -3 Query: 469 AAIWGKDCAEFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLE 290 AA WG D EF+PER L + +R ++ F F +G R C A V + + A+++ Sbjct: 392 AATWGPDVEEFRPERHLDSSVDYRGQA-FELIPFGSGRRICPAISFAVVLNEVVLANLVH 450 Query: 289 EF 284 F Sbjct: 451 RF 452
>CP6D4_DROME (Q9VCW1) Probable cytochrome P450 6d4 (EC 1.14.-.-) (CYPVID4)| Length = 515 Score = 37.7 bits (86), Expect = 0.015 Identities = 24/92 (26%), Positives = 43/92 (46%) Frame = -3 Query: 451 DCAEFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTVDV 272 D + PER+ E+ + P + + F GPR C+ + M + K +L+ F V+V Sbjct: 426 DPETYDPERFSEESRNYNPTA---FMPFGEGPRICIAQRMGRINSKLAIIKILQNFNVEV 482 Query: 271 VRKNAGSSAPEHVLSVTLRMKGGLPVQIRRRV 176 + + S + L K G+ V++ +RV Sbjct: 483 MSR---SEIEFENSGIALIPKHGVRVRLSKRV 511
>CP17A_FELCA (Q9GMC8) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 508 Score = 37.4 bits (85), Expect = 0.019 Identities = 19/57 (33%), Positives = 31/57 (54%) Frame = -3 Query: 442 EFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTVDV 272 +F PER+L + Y F AGPR+CLG+ +A ++ A +L+ F ++V Sbjct: 411 QFMPERFLDPTRSQLISPSLSYLPFGAGPRSCLGESLARQEVFLFMAWLLQRFDLEV 467
>CP17A_SHEEP (Q29497) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 509 Score = 37.4 bits (85), Expect = 0.019 Identities = 17/56 (30%), Positives = 30/56 (53%) Frame = -3 Query: 439 FKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTVDV 272 F PER+L G Y F AGPR+C+G+ +A ++ + +L+ F +++ Sbjct: 412 FMPERFLDPTGTQLISPSLSYLPFGAGPRSCVGEMLARQELFLFMSRLLQRFNLEI 467
>CP17A_CAPHI (Q9N0U7) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 509 Score = 37.4 bits (85), Expect = 0.019 Identities = 17/56 (30%), Positives = 30/56 (53%) Frame = -3 Query: 439 FKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTVDV 272 F PER+L G Y F AGPR+C+G+ +A ++ + +L+ F +++ Sbjct: 412 FMPERFLDPTGTQLISPSLSYLPFGAGPRSCVGEMLARQELFLFMSRLLQRFNLEI 467
>C12E1_DROME (Q9VGZ0) Probable cytochrome P450 12e1, mitochondrial precursor (EC| 1.14.-.-) (CYPXIIE1) Length = 514 Score = 37.4 bits (85), Expect = 0.019 Identities = 18/59 (30%), Positives = 29/59 (49%), Gaps = 4/59 (6%) Frame = -3 Query: 442 EFKPERWLGENG----AFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTV 278 EF PERWL + +PF Y F GPR+C GK + + ++ + ++ F + Sbjct: 425 EFIPERWLRDESNSHLVGETATPFMYLPFGFGPRSCAGKRIVDMMLEIAISRLVRNFKI 483
>CP3AH_CAVPO (Q64409) Cytochrome P450 3A17 (EC 1.14.14.1) (CYPIIIA17)| Length = 503 Score = 37.4 bits (85), Expect = 0.019 Identities = 19/54 (35%), Positives = 29/54 (53%) Frame = -3 Query: 442 EFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFT 281 EF+PER+ +N P+ Y F GPR C+G MA + +K +L+ F+ Sbjct: 413 EFRPERFSKKNK--ENIDPYIYMPFGNGPRNCIGMRMALMNLKLALIRLLQNFS 464
>CP3AE_CAVPO (Q64417) Cytochrome P450 3A14 (EC 1.14.14.1) (CYPIIIA14)| Length = 503 Score = 37.4 bits (85), Expect = 0.019 Identities = 19/54 (35%), Positives = 29/54 (53%) Frame = -3 Query: 442 EFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFT 281 EF+PER+ +N P+ Y F GPR C+G MA + +K +L+ F+ Sbjct: 413 EFRPERFSKKNK--ENIDPYIYMPFGNGPRNCIGMRMALMNLKLALIRLLQNFS 464
>CP19A_RABIT (Q29605) Cytochrome P450 19A1 (EC 1.14.14.1) (Aromatase) (CYPXIX)| (Estrogen synthetase) (P-450AROM) Length = 503 Score = 37.4 bits (85), Expect = 0.019 Identities = 23/58 (39%), Positives = 30/58 (51%), Gaps = 1/58 (1%) Frame = -3 Query: 436 KPERWLGENGAFRPESPFRY-TVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTVDVVR 266 KP + EN F P+RY F GPR C GK +A V MK I ++L F V ++ Sbjct: 409 KPNEFTLEN--FAKNVPYRYFQPFGFGPRGCAGKYIAMVMMKVILVTLLRRFQVKALQ 464
>C71AK_ARATH (Q9T0K2) Cytochrome P450 71A20 (EC 1.14.-.-)| Length = 495 Score = 37.4 bits (85), Expect = 0.019 Identities = 20/59 (33%), Positives = 30/59 (50%) Frame = -3 Query: 460 WGKDCAEFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEF 284 WG D EFKPER L N F+ + F++ F +G R C G + A++++ F Sbjct: 402 WGTDAEEFKPERHLDTNLDFQGQD-FKFIPFGSGKRICPGIGFTSALIGVTLANIVKRF 459
>CP26B_BRARE (Q6EIG3) Cytochrome P450 26B1 (EC 1.14.-.-) (Cyp26B1)| (Retinoic-acid metabolizing cytochrome) Length = 511 Score = 37.4 bits (85), Expect = 0.019 Identities = 20/53 (37%), Positives = 29/53 (54%) Frame = -3 Query: 454 KDCAEFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASV 296 KD F P+R+ E R E F Y F G R+CLGK++A + +K +A + Sbjct: 406 KDVEAFDPDRFSPERSEDR-EGRFHYLPFGGGVRSCLGKQLATLFLKLLAVEL 457
>CYPD_BACSU (O08394) Probable bifunctional P-450:NADPH-P450 reductase 1| [Includes: Cytochrome P450 102 (EC 1.14.14.1); NADPH--cytochrome P450 reductase (EC 1.6.2.4)] Length = 1061 Score = 37.4 bits (85), Expect = 0.019 Identities = 19/61 (31%), Positives = 30/61 (49%) Frame = -3 Query: 460 WGKDCAEFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFT 281 WGKD EF+PER+ ++ Y F G R C+G + A + + +L+ FT Sbjct: 370 WGKDAEEFRPERFEHQDQV----PHHAYKPFGNGQRACIGMQFALHEATLVLGMILKYFT 425 Query: 280 V 278 + Sbjct: 426 L 426
>CP3AS_BOVIN (P79102) Cytochrome P450 3A28 (EC 1.14.14.1) (CYPIIIA28)| Length = 507 Score = 37.4 bits (85), Expect = 0.019 Identities = 19/54 (35%), Positives = 28/54 (51%) Frame = -3 Query: 442 EFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFT 281 EF+PER+ N +P+ Y F GPR CLG A + +K +L+ F+ Sbjct: 413 EFRPERFSKNNKD--SINPYVYLPFGTGPRNCLGMRFAIMNIKLALVRILQNFS 464
>C75A4_GENTR (Q96581) Flavonoid 3',5'-hydroxylase (EC 1.14.13.88) (F3'5'H)| (Cytochrome P450 75A4) Length = 516 Score = 37.4 bits (85), Expect = 0.019 Identities = 21/63 (33%), Positives = 32/63 (50%), Gaps = 2/63 (3%) Frame = -3 Query: 466 AIWGKDCAEFKPERWL-GENGAFRPE-SPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVL 293 ++WG + EF PER+L G N P + F F AG R C G M + ++ I +++ Sbjct: 412 SVWGDNPNEFDPERFLYGRNAKIDPRGNHFELIPFGAGRRICAGTRMGILLVEYILGTLV 471 Query: 292 EEF 284 F Sbjct: 472 HSF 474
>CP6J1_BLAGE (Q964R1) Cytochrome P450 6j1 (EC 1.14.-.-) (CYPVIJ1)| Length = 501 Score = 37.4 bits (85), Expect = 0.019 Identities = 20/56 (35%), Positives = 28/56 (50%) Frame = -3 Query: 445 AEFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTV 278 A+F PER+ +N P F Y F GPR C+G +Q+K+ +L F V Sbjct: 414 AKFDPERFSEKNKQNIPH--FAYMPFGEGPRNCIGMRFGSMQVKAALIHILSNFEV 467
>CP3A6_RABIT (P11707) Cytochrome P450 3A6 (EC 1.14.14.1) (CYPIIIA6) (P450-3C)| Length = 501 Score = 37.4 bits (85), Expect = 0.019 Identities = 19/60 (31%), Positives = 33/60 (55%) Frame = -3 Query: 442 EFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTVDVVRK 263 EF+PER+ +N +P+ Y F AGPR CLG A + +K +++ F+ + ++ Sbjct: 411 EFRPERFSKKNKD--NINPYIYHPFGAGPRNCLGMRFALMNIKLALVRLMQNFSFKLCKE 468
>C28A5_DROME (Q9V419) Probable cytochrome P450 28a5 (EC 1.14.-.-) (CYPXXVIIIA5)| Length = 505 Score = 37.4 bits (85), Expect = 0.019 Identities = 26/88 (29%), Positives = 44/88 (50%), Gaps = 2/88 (2%) Frame = -3 Query: 439 FKPERWLGENGA--FRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTVDVVR 266 F+PER+L + A FR F F GPR C+G A VQ+K+ ++ +F V + Sbjct: 420 FQPERFLEPDAAKTFRERGVFMG--FGDGPRVCIGMRFATVQIKAAIVELISKFNVKIND 477 Query: 265 KNAGSSAPEHVLSVTLRMKGGLPVQIRR 182 K + E +T ++GG+ + + + Sbjct: 478 KTRKDNDYEPGQIIT-GLRGGIWLDLEK 504
>CP2H2_CHICK (P20678) Cytochrome P450 2H2 (EC 1.14.14.1) (CYPIIH2) (P450 PCHP7)| Length = 491 Score = 37.4 bits (85), Expect = 0.019 Identities = 22/69 (31%), Positives = 35/69 (50%), Gaps = 6/69 (8%) Frame = -3 Query: 454 KDCAEFK------PERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVL 293 +DC EF P +L NG FR + F F AG R C G+ +A +++ S+L Sbjct: 397 QDCKEFPNPEKFDPGHFLNANGTFRKSNYF--MPFSAGKRICAGEGLARMELFLFLTSIL 454 Query: 292 EEFTVDVVR 266 + F++ V+ Sbjct: 455 QNFSLKPVK 463
>CC44_CAEEL (Q09660) Probable cytochrome P450 CYP44 (EC 1.14.-.-)| Length = 489 Score = 37.4 bits (85), Expect = 0.019 Identities = 18/55 (32%), Positives = 28/55 (50%) Frame = -3 Query: 442 EFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTV 278 EFKP+RWL ++ + PF Y F GPR C G+ A + + A + + + Sbjct: 410 EFKPQRWLEKS---KEVHPFAYLPFGFGPRMCAGRRFAEQDLLTSLAKLCGNYDI 461
>CP2E1_MACFA (P33266) Cytochrome P450 2E1 (EC 1.14.14.1) (CYPIIE1) (P450-MKJ1)| (Fragment) Length = 449 Score = 37.4 bits (85), Expect = 0.019 Identities = 18/58 (31%), Positives = 34/58 (58%) Frame = -3 Query: 451 DCAEFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTV 278 D +FKPE + E+G F+ F+ F AG R C G+ +A +++ + +++L+ F + Sbjct: 361 DPEKFKPEHLVDESGKFKYSDYFK--PFSAGKRVCAGEGLARMELFLLLSAILQHFNL 416
>CP133_DROME (Q9VGB3) Probable cytochrome P450 313a3 (EC 1.14.-.-)| (CYPCCCXIIIA3) Length = 492 Score = 37.0 bits (84), Expect = 0.025 Identities = 18/61 (29%), Positives = 28/61 (45%) Frame = -3 Query: 460 WGKDCAEFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFT 281 WG D + F P+ +L +N R P+ Y F G R C+G + + K + +L Sbjct: 403 WGTDPSSFNPDHFLPDN--VRDRHPYAYIPFSKGRRNCIGWKYGLMSSKLALSKILRNCK 460 Query: 280 V 278 V Sbjct: 461 V 461
>C11B2_HUMAN (P19099) Cytochrome P450 11B2, mitochondrial precursor (EC| 1.14.15.4) (EC 1.14.15.5) (CYPXIB2) (P-450Aldo) (Aldosterone synthase) (ALDOS) (Aldosterone-synthesizing enzyme) (Steroid 18-hydroxylase) (P-450C18) Length = 503 Score = 37.0 bits (84), Expect = 0.025 Identities = 19/57 (33%), Positives = 30/57 (52%) Frame = -3 Query: 439 FKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTVDVV 269 + P+RWL G+ R F + F G R CLG+ +A +M + VL+ F V+ + Sbjct: 423 YNPQRWLDIRGSGRN---FHHVPFGFGMRQCLGRRLAEAEMLLLLHHVLKHFLVETL 476
>C4G15_DROME (Q9VYY4) Cytochrome P450 4g15 (EC 1.14.-.-) (CYPIVG15)| Length = 574 Score = 37.0 bits (84), Expect = 0.025 Identities = 17/54 (31%), Positives = 33/54 (61%) Frame = -3 Query: 439 FKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTV 278 F P+ +L E A R + + F AGPR+C+G++ A +++K + +++L + V Sbjct: 491 FDPDNFLPERQANRHY--YAFVPFSAGPRSCVGRKYAMLKLKILLSTILRNYRV 542
>CP11A_PIG (P10612) Cytochrome P450 11A1, mitochondrial precursor (EC| 1.14.15.6) (CYPXIA1) (P450(scc)) (Cholesterol side-chain cleavage enzyme) (Cholesterol desmolase) Length = 520 Score = 37.0 bits (84), Expect = 0.025 Identities = 20/57 (35%), Positives = 30/57 (52%) Frame = -3 Query: 442 EFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTVDV 272 +F P RWLG+ R FR F G R C+G+ +A ++M +LE F V++ Sbjct: 433 QFDPTRWLGKE---RDLIHFRNLGFGWGVRQCVGRRIAELEMTLFLIHILENFKVEL 486
>C12C1_DROME (Q9VVR9) Probable cytochrome P450 12c1, mitochondrial precursor (EC| 1.14.-.-) (CYPXIIC1) Length = 524 Score = 37.0 bits (84), Expect = 0.025 Identities = 19/63 (30%), Positives = 32/63 (50%), Gaps = 7/63 (11%) Frame = -3 Query: 442 EFKPERWLGENGAFRPE-------SPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEF 284 EF PERWL + + + F Y F GPR C+GK + ++M+ A+++ F Sbjct: 432 EFIPERWLRRKDDDKSDVLMNKDLNAFIYLPFGFGPRMCVGKRIVDLEMELTVANLVRNF 491 Query: 283 TVD 275 ++ Sbjct: 492 HIE 494
>CP6T3_DROME (Q9V676) Probable cytochrome P450 6t3 (EC 1.14.-.-) (CYPVIT3)| Length = 501 Score = 37.0 bits (84), Expect = 0.025 Identities = 20/66 (30%), Positives = 32/66 (48%) Frame = -3 Query: 460 WGKDCAEFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFT 281 W + C F PER+ E R P Y F AGP C+G + +Q+K +L+++ Sbjct: 410 WPEPCV-FDPERFGPERS--RHIHPMTYIPFGAGPHGCIGSRLGVLQLKLGIVHILKQYW 466 Query: 280 VDVVRK 263 V+ + Sbjct: 467 VETCER 472
>CP2R1_MOUSE (Q6VVW9) Cytochrome P450 2R1 (EC 1.14.14.-) (Vitamin D| 25-hydroxylase) Length = 501 Score = 37.0 bits (84), Expect = 0.025 Identities = 21/57 (36%), Positives = 31/57 (54%) Frame = -3 Query: 454 KDCAEFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEF 284 KD F PER+L NG F + F G R CLG+++A ++M S+L++F Sbjct: 415 KDPDMFYPERFLDSNGYFTKKEAL--IPFSLGRRHCLGEQLARMEMFLFFTSLLQQF 469
>CP51_SORBI (P93846) Cytochrome P450 51 (EC 1.14.13.70) (CYPLI) (P450-LIA1)| (Obtusifoliol 14-alpha demethylase) Length = 492 Score = 36.6 bits (83), Expect = 0.033 Identities = 26/93 (27%), Positives = 45/93 (48%), Gaps = 1/93 (1%) Frame = -3 Query: 454 KDCAEFKPERWLGENGAFRPESPFRYTVFHAGPRTCLGKEMAYVQMKSIAASVLEEFTVD 275 K+ + P+R+ + F Y F G CLG+ AY+Q+K+I +L F + Sbjct: 399 KNPDSYDPDRFGPGREEDKAAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFE 458 Query: 274 VVRKNAGSSAPEHVL-SVTLRMKGGLPVQIRRR 179 +V S PE+ ++ + +KG + V +RR Sbjct: 459 LV-----SPFPENDWNAMVVGIKGEVMVNYKRR 486 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 65,195,616 Number of Sequences: 219361 Number of extensions: 1253027 Number of successful extensions: 4236 Number of sequences better than 10.0: 423 Number of HSP's better than 10.0 without gapping: 4024 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 4151 length of database: 80,573,946 effective HSP length: 103 effective length of database: 57,979,763 effective search space used: 3072927439 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
