ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
menu 
| Clone Name | rbart31c01 |
|---|---|
| Clone Library Name | barley_pub |
>C72A1_CATRO (Q05047) Cytochrome P450 72A1 (EC 1.3.3.9) (CYPLXXII) (Secologanin| synthase) (SLS) Length = 524 Score = 134 bits (338), Expect = 1e-31 Identities = 60/118 (50%), Positives = 83/118 (70%) Frame = -3 Query: 474 DLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPNALLSFSS 295 D ++G +P GT + +P +HR+K +WGEDA EF PMRF +GV A K+ L FS Sbjct: 406 DTKLGSYTIPAGTQVMLPTVMLHREKSIWGEDAMEFNPMRFVDGVANATKNNVTYLPFSW 465 Query: 294 GPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITLRPKFGLPMILKSLE 121 GPR C+GQNFA+++AK +AMILQRF F ++P YVHAP ++T++P+FG +I K LE Sbjct: 466 GPRVCLGQNFALLQAKLGLAMILQRFKFDVAPSYVHAPFTILTVQPQFGSHVIYKKLE 523
>CP4B1_RAT (P15129) Cytochrome P450 4B1 (EC 1.14.14.1) (CYPIVB1) (P450-isozyme| 5) (P450 L-2) Length = 510 Score = 91.7 bits (226), Expect = 1e-18 Identities = 50/114 (43%), Positives = 69/114 (60%) Frame = -3 Query: 465 VGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPNALLSFSSGPR 286 V G +P G++I++ I +HR+ VW D F P+RF + AG+HP A + FS+GPR Sbjct: 393 VDGRSLPAGSLISLHIYALHRNSTVW-PDPEVFDPLRF-SPENAAGRHPFAFMPFSAGPR 450 Query: 285 SCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITLRPKFGLPMILKSL 124 +CIGQ FAM E K V A+ L RF FSL P + + + LR K G+ + LK L Sbjct: 451 NCIGQQFAMNEMKVVTALCLLRFEFSLDPSKMPIKVPQLILRSKNGIHLYLKPL 504
>CP4B1_RABIT (P15128) Cytochrome P450 4B1 (EC 1.14.14.1) (CYPIVB1) (P450-isozyme| 5) Length = 506 Score = 90.9 bits (224), Expect = 2e-18 Identities = 48/114 (42%), Positives = 70/114 (61%) Frame = -3 Query: 465 VGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPNALLSFSSGPR 286 V G +P G++I++ I +HR+ +VW D F P+RF + +G+HP A + FS+GPR Sbjct: 389 VDGRSLPAGSLISLHIYALHRNSDVW-PDPEVFDPLRF-SPENSSGRHPYAFIPFSAGPR 446 Query: 285 SCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITLRPKFGLPMILKSL 124 +CIGQ FAM E K V A+ L RF FS+ P + + + LR K G+ + LK L Sbjct: 447 NCIGQQFAMNEMKVVTALCLLRFEFSVDPLRLPIKLPQLVLRSKNGIHLYLKPL 500
>CP4B1_MOUSE (Q64462) Cytochrome P450 4B1 (EC 1.14.14.1) (CYPIVB1)| Length = 511 Score = 88.2 bits (217), Expect = 1e-17 Identities = 48/114 (42%), Positives = 67/114 (58%) Frame = -3 Query: 465 VGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPNALLSFSSGPR 286 V G +P G++I++ I +HR+ VW D F P+RF + G+HP A + FS+GPR Sbjct: 394 VDGRSLPAGSLISLHIYALHRNSAVW-PDPEVFDPLRF-SPENMTGRHPFAFMPFSAGPR 451 Query: 285 SCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITLRPKFGLPMILKSL 124 +CIGQ FAM E K V A+ L RF FS P + + + LR K G+ + LK L Sbjct: 452 NCIGQQFAMNEMKVVTALCLLRFEFSPDPSKIPIKVPQLILRSKNGIHLYLKPL 505
>CP4B1_HUMAN (P13584) Cytochrome P450 4B1 (EC 1.14.14.1) (CYPIVB1) (P450-HP)| Length = 511 Score = 86.3 bits (212), Expect = 4e-17 Identities = 49/114 (42%), Positives = 65/114 (57%) Frame = -3 Query: 465 VGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPNALLSFSSGPR 286 V G +P G++I++ I +HR+ VW D F +RF + +HP A + FS+GPR Sbjct: 394 VDGRSLPAGSLISMHIYALHRNSAVW-PDPEVFDSLRFSTE-NASKRHPFAFMPFSAGPR 451 Query: 285 SCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITLRPKFGLPMILKSL 124 +CIGQ FAM E K V AM L RF FSL P + M + LR K G + LK L Sbjct: 452 NCIGQQFAMSEMKVVTAMCLLRFEFSLDPSRLPIKMPQLVLRSKNGFHLHLKPL 505
>CP3AO_SHEEP (Q29496) Cytochrome P450 3A24 (EC 1.14.14.1) (CYPIIIA24)| Length = 503 Score = 84.0 bits (206), Expect = 2e-16 Identities = 39/95 (41%), Positives = 57/95 (60%) Frame = -3 Query: 495 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPN 316 + R D+E+ G+ +PKGT +T+PI +HRD ++W E EF+P RF + +P Sbjct: 373 LDRLCKKDVEIHGVSIPKGTAVTVPIFVLHRDPQLWPE-PEEFRPERFSK-KNKDSINPY 430 Query: 315 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSF 211 L F +GPR+CIG FA++ K I +LQ FSF Sbjct: 431 VYLPFGTGPRNCIGMRFAIMNMKLAIVRVLQNFSF 465
>CP3AT_PIG (P79401) Cytochrome P450 3A29 (EC 1.14.14.1) (CYPIIIA29)| Length = 503 Score = 82.8 bits (203), Expect = 5e-16 Identities = 39/97 (40%), Positives = 59/97 (60%) Frame = -3 Query: 501 AAIQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKH 322 A ++R D+E+ G+ VPKGTV+ +P+ +HRD ++W E EF+P RF + + Sbjct: 371 ARLERACKKDVEIHGVFVPKGTVVVVPVFVLHRDPDLWPE-PEEFRPERFSK-KHKDTIN 428 Query: 321 PNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSF 211 P L F +GPR+CIG FA++ K + +LQ FSF Sbjct: 429 PYTYLPFGTGPRNCIGMRFALMNMKLALVRVLQNFSF 465
>CP3AC_CANFA (P24463) Cytochrome P450 3A12 (EC 1.14.14.1) (CYPIIIA12)| (P450-PBD-1) Length = 503 Score = 82.8 bits (203), Expect = 5e-16 Identities = 38/95 (40%), Positives = 58/95 (61%) Frame = -3 Query: 495 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPN 316 ++R D+E+ G+ +PKGTV+ +P T+HRD+ +W E EF+P RF + +P Sbjct: 373 LERVCKKDVEISGVFIPKGTVVMVPTFTLHRDQSLWPE-PEEFRPERFSR-KNKDSINPY 430 Query: 315 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSF 211 L F +GPR+CIG FA++ K + +LQ FSF Sbjct: 431 TYLPFGTGPRNCIGMRFAIMNMKLALVRVLQNFSF 465
>C13A6_CAEEL (Q27515) Putative cytochrome P450 CYP13A6 (EC 1.14.-.-)| Length = 518 Score = 81.3 bits (199), Expect = 1e-15 Identities = 40/115 (34%), Positives = 63/115 (54%), Gaps = 3/115 (2%) Frame = -3 Query: 489 RKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPNAL 310 RK + + G+ +G I + T+H + +WGED +FKP R+ENG +H + Sbjct: 394 RKCMRETTINGVNFDEGMNIQVDTWTLHHNPRIWGEDVEDFKPERWENGACEHLEHNGSY 453 Query: 309 LSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVI---TLRPK 154 + F SGPR CIG A +E K ++A IL+ +SF + K P+ ++ TL P+ Sbjct: 454 IPFGSGPRQCIGMRLAQMEQKILLAQILKEYSFR-TTKNTQIPVKLVGKLTLSPE 507
>CP3AR_ONCMY (O42563) Cytochrome P450 3A27 (EC 1.14.14.1) (CYPIIIA27)| Length = 518 Score = 80.5 bits (197), Expect = 2e-15 Identities = 39/97 (40%), Positives = 57/97 (58%) Frame = -3 Query: 495 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPN 316 ++R A +E+ GI +PK ++ +P T+HRD E+W D EFKP RF + P Sbjct: 378 LERVAKKTVEINGIVIPKDCIVLVPTWTLHRDPEIWS-DPEEFKPERFSKE-NKESIDPY 435 Query: 315 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSL 205 + F +GPR+CIG FA+I K + ILQ F+FS+ Sbjct: 436 TYMPFGAGPRNCIGMRFALIMIKLAMVEILQSFTFSV 472
>CP3AJ_CAPAE (P79152) Cytochrome P450 3A19 (EC 1.14.14.1) (CYPIIIA19) (Fragment)| Length = 218 Score = 80.5 bits (197), Expect = 2e-15 Identities = 39/110 (35%), Positives = 62/110 (56%) Frame = -3 Query: 495 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPN 316 ++R D+E+ G+ +PKGT + +P+ +H + E W E EF+P RF + G +P Sbjct: 84 LERLCKKDVEIHGVSIPKGTTVMVPLFVLHNNPEFWPEP-EEFRPERFSKK-NKDGINPY 141 Query: 315 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVIT 166 L F +GPR+C+G FA++ K + ILQ FSF + K P+ + T Sbjct: 142 VYLPFGTGPRNCVGMRFALMNIKLALVRILQNFSF-IPCKETQIPLKLYT 190
>CP4V3_MOUSE (Q9DBW0) Cytochrome P450 4V3 (EC 1.14.-.-)| Length = 525 Score = 80.5 bits (197), Expect = 2e-15 Identities = 56/125 (44%), Positives = 74/125 (59%), Gaps = 5/125 (4%) Frame = -3 Query: 489 RKAGSDLEVGGIKVPKGT-VITIPIATIHRDKEVWGEDANEFKPMRF--ENGVTRAGKHP 319 R D EVGG KV KGT I IP A +HRD + D EF+P RF EN G+HP Sbjct: 400 RSLSEDCEVGGYKVTKGTEAIIIPYA-LHRDPRYF-PDPEEFRPERFFPENS---QGRHP 454 Query: 318 NALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPM--DVITLRPKFGL 145 A + FS+GPR+CIGQ FA++E K ++A IL++F + K + D+I LRP G+ Sbjct: 455 YAYVPFSAGPRNCIGQKFAVMEEKTILACILRQFWVESNQKREELGLAGDLI-LRPNNGI 513 Query: 144 PMILK 130 + LK Sbjct: 514 WIKLK 518
>CP4S3_DROME (Q9VXY0) Probable cytochrome P450 4s3 (EC 1.14.-.-) (CYPIVS3)| Length = 495 Score = 79.0 bits (193), Expect = 7e-15 Identities = 51/122 (41%), Positives = 67/122 (54%) Frame = -3 Query: 489 RKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPNAL 310 RK DLEVG + VPKG I+ I +HRD + + D F P RF V HP A Sbjct: 370 RKVLEDLEVGKLTVPKGASISCLIYMLHRDPKNF-PDPERFDPDRFL--VNEKQMHPFAF 426 Query: 309 LSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITLRPKFGLPMILK 130 +FS+GPR+CIGQ FAM+E K +AM+L+ + F P H P + L K G + L+ Sbjct: 427 AAFSAGPRNCIGQKFAMLELKTSLAMLLRSYRF--LPDKDHQPKPLAELVTKSGNGIRLR 484 Query: 129 SL 124 L Sbjct: 485 IL 486
>CP3AI_RAT (Q64581) Cytochrome P450 3A18 (EC 1.14.14.1) (CYPIIIA18)| (P450(6)beta-2) Length = 497 Score = 79.0 bits (193), Expect = 7e-15 Identities = 39/94 (41%), Positives = 55/94 (58%) Frame = -3 Query: 495 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPN 316 + R + D+E+ G+ +PKGTV+TIPI +HR+ E W E EF P RF + P Sbjct: 373 LDRVSKKDVEINGVFIPKGTVVTIPIYPLHRNPEYWLE-PEEFNPERFSK-ENKGSIDPY 430 Query: 315 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFS 214 L F +GPR+CIG FA+I K + +LQ F+ Sbjct: 431 VYLPFGNGPRNCIGMRFALISMKLAVIGVLQNFN 464
>C13A5_CAEEL (Q27514) Putative cytochrome P450 CYP13A5 (EC 1.14.-.-)| Length = 520 Score = 79.0 bits (193), Expect = 7e-15 Identities = 39/96 (40%), Positives = 57/96 (59%) Frame = -3 Query: 489 RKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPNAL 310 RK + V G+++ KGT + + T+H D +VWGEDANEF+P R+E+G Sbjct: 396 RKCMKETNVLGVQIEKGTNVQVDTWTLHYDPKVWGEDANEFRPERWESG-DELFYAKGGY 454 Query: 309 LSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLS 202 L F GPR CIG AM+E K ++ IL++++F S Sbjct: 455 LPFGMGPRICIGMRLAMMEKKMLLTHILKKYTFETS 490
>CP3AS_BOVIN (P79102) Cytochrome P450 3A28 (EC 1.14.14.1) (CYPIIIA28)| Length = 507 Score = 78.2 bits (191), Expect = 1e-14 Identities = 35/95 (36%), Positives = 56/95 (58%) Frame = -3 Query: 495 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPN 316 ++R D+E+ G+ +PKGT + +P+ +H + E+W E EF+P RF + +P Sbjct: 373 LERVCKKDVEIHGVTIPKGTTVLVPLFVLHNNPELWPEP-EEFRPERFSKN-NKDSINPY 430 Query: 315 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSF 211 L F +GPR+C+G FA++ K + ILQ FSF Sbjct: 431 VYLPFGTGPRNCLGMRFAIMNIKLALVRILQNFSF 465
>CP3A9_RAT (P51538) Cytochrome P450 3A9 (EC 1.14.14.1) (CYPIIIA9) (P450-OLF3)| (Olfactive) (3AH15) Length = 503 Score = 78.2 bits (191), Expect = 1e-14 Identities = 37/95 (38%), Positives = 56/95 (58%) Frame = -3 Query: 495 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPN 316 ++R +D+E+ G+ +PKGTV+ IP +H+D W E EF+P RF + +P Sbjct: 373 LERVCKTDVEINGVFIPKGTVVMIPTFALHKDPHYWPE-PEEFRPERFSK-KNQDNINPY 430 Query: 315 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSF 211 L F +GPR+CIG FA++ K + +LQ FSF Sbjct: 431 MYLPFGNGPRNCIGMRFALMNMKVALFRVLQNFSF 465
>C356_FUNHE (Q8AXY5) Cytochrome P450 3A56 (EC 1.14.14.1) (CYPIIIA56)| Length = 496 Score = 77.8 bits (190), Expect = 2e-14 Identities = 40/99 (40%), Positives = 58/99 (58%) Frame = -3 Query: 501 AAIQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKH 322 A ++R A + +E+ GI +PK V+ IP +HRD E+W E FKP RF + Sbjct: 370 ARLERVAKAAVEINGIVIPKDMVVMIPTWPLHRDPEIWPEP-EAFKPERFSKK-NKDNID 427 Query: 321 PNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSL 205 P + F SGPR+CIG FA++ K + ILQ++SFS+ Sbjct: 428 PYIYMPFGSGPRNCIGMRFALVLIKLAVVEILQQYSFSV 466
>CP3AD_MOUSE (Q64464) Cytochrome P450 3A13 (EC 1.14.14.1) (CYPIIIA13)| Length = 503 Score = 77.8 bits (190), Expect = 2e-14 Identities = 37/94 (39%), Positives = 56/94 (59%) Frame = -3 Query: 495 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPN 316 ++R +D+E+ G+ +PKGTV+ IP +H+D + W E EF+P RF + +P Sbjct: 373 LERVCKTDVEINGLFIPKGTVVMIPTFALHKDPKYWPE-PEEFRPERFSK-KNQDSINPY 430 Query: 315 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFS 214 L F SGPR+CIG FA+I K + +LQ F+ Sbjct: 431 MYLPFGSGPRNCIGMRFALINMKVALVRVLQNFT 464
>CP3A1_RAT (P04800) Cytochrome P450 3A1 (EC 1.14.14.1) (CYPIIIA1) (P450-PCN1)| Length = 504 Score = 77.4 bits (189), Expect = 2e-14 Identities = 37/95 (38%), Positives = 55/95 (57%) Frame = -3 Query: 495 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPN 316 ++R D+E+ G+ +PKG+V+ IP +HRD + W E EF+P RF + P Sbjct: 374 LERVCKKDVEINGVFMPKGSVVMIPSYALHRDPQHWPEP-EEFRPERFSKE-NKGSIDPY 431 Query: 315 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSF 211 L F +GPR+CIG FA++ K + +LQ FSF Sbjct: 432 VYLPFGNGPRNCIGMRFALMNMKLALTKVLQNFSF 466
>CPXB_BACME (P14779) Bifunctional P-450:NADPH-P450 reductase (Cytochrome| P450(BM-3)) (P450BM-3) [Includes: Cytochrome P450 102 (EC 1.14.14.1); NADPH--cytochrome P450 reductase (EC 1.6.2.4)] Length = 1048 Score = 77.4 bits (189), Expect = 2e-14 Identities = 42/111 (37%), Positives = 62/111 (55%), Gaps = 1/111 (0%) Frame = -3 Query: 483 AGSDLEVGG-IKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPNALL 307 A D +GG + KG + + I +HRDK +WG+D EF+P RFEN + +A Sbjct: 335 AKEDTVLGGEYPLEKGDELMVLIPQLHRDKTIWGDDVEEFRPERFEN---PSAIPQHAFK 391 Query: 306 SFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITLRPK 154 F +G R+CIGQ FA+ EA V+ M+L+ F F Y + +TL+P+ Sbjct: 392 PFGNGQRACIGQQFALHEATLVLGMMLKHFDFEDHTNYELDIKETLTLKPE 442
>CP4X1_RAT (Q8K4D6) Cytochrome P450 4X1 (EC 1.14.14.1) (CYPIVX1)| Length = 507 Score = 77.4 bits (189), Expect = 2e-14 Identities = 48/114 (42%), Positives = 61/114 (53%), Gaps = 2/114 (1%) Frame = -3 Query: 459 GIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRF--ENGVTRAGKHPNALLSFSSGPR 286 G +P G + + I +H + VW +D F P+RF EN R HP A L FSSGPR Sbjct: 395 GHSLPAGMTVVLSIWGLHHNPAVW-KDPKVFDPLRFTKENSEQR---HPCAFLPFSSGPR 450 Query: 285 SCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITLRPKFGLPMILKSL 124 +CIGQ FAM+E K IA+ L RF + A LRPK G+ + LK L Sbjct: 451 NCIGQQFAMLELKVAIALTLLRFRVAADLTRPPAFSSHTVLRPKHGIYLHLKKL 504
>C330_FUNHE (Q9PVE8) Cytochrome P450 3A30 (EC 1.14.14.1) (CYPIIIA30)| Length = 496 Score = 77.4 bits (189), Expect = 2e-14 Identities = 39/99 (39%), Positives = 58/99 (58%) Frame = -3 Query: 501 AAIQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKH 322 A ++R A + +E+ G+ +PK V+ IP +HRD E+W E FKP RF + Sbjct: 370 ARLERVAKAAVEINGVVIPKDMVVMIPTWPLHRDPEIWPEP-EAFKPERFSKK-NKDNID 427 Query: 321 PNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSL 205 P + F SGPR+CIG FA++ K + ILQ++SFS+ Sbjct: 428 PYIYMPFGSGPRNCIGMRFALVLIKLAVVEILQQYSFSV 466
>CP4D2_DROME (Q27589) Cytochrome P450 4d2 (EC 1.14.-.-) (CYPIVD2)| Length = 501 Score = 75.9 bits (185), Expect = 6e-14 Identities = 48/123 (39%), Positives = 74/123 (60%), Gaps = 1/123 (0%) Frame = -3 Query: 495 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPN 316 I R D+E+ G +P GT T+ I + RD E + E +EF+P RF+ V + HP Sbjct: 381 IGRWFAEDVEIRGKHIPAGTNFTMGIFVLLRDPEYF-ESPDEFRPERFDADVPQI--HPY 437 Query: 315 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFS-FSLSPKYVHAPMDVITLRPKFGLPM 139 A + FS+GPR+CIGQ FAM+E K+ ++ +L+ F L P+ H+ M+++ LR G+ + Sbjct: 438 AYIPFSAGPRNCIGQKFAMLEMKSTVSKLLRHFELLPLGPEPRHS-MNIV-LRSANGVHL 495 Query: 138 ILK 130 LK Sbjct: 496 GLK 498
>CP3AG_MOUSE (Q64481) Cytochrome P450 3A16 (EC 1.14.14.1) (CYPIIIA16)| Length = 504 Score = 75.9 bits (185), Expect = 6e-14 Identities = 37/95 (38%), Positives = 53/95 (55%) Frame = -3 Query: 495 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPN 316 +QR D+E+ GI +PKG+ + IP +H D + W E EF+P RF + P Sbjct: 374 LQRVCKKDVEINGIYIPKGSTVIIPSYVLHHDPQHWPEP-EEFQPERFSKE-NKGSIDPY 431 Query: 315 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSF 211 L F +GPR+CIG FA++ K + +LQ FSF Sbjct: 432 VYLPFGNGPRNCIGMRFALMNMKLALIKVLQNFSF 466
>CP134_DROME (Q9VG40) Probable cytochrome P450 313a4 (EC 1.14.-.-)| (CYPCCCXIIIA4) Length = 478 Score = 75.9 bits (185), Expect = 6e-14 Identities = 40/99 (40%), Positives = 57/99 (57%), Gaps = 1/99 (1%) Frame = -3 Query: 495 IQRKAGSDLEVG-GIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHP 319 + R+ DL++ GI VPKG I I I +HR K++WG DA F P F + KHP Sbjct: 353 VSRQTSQDLKLSNGIVVPKGVQIAIDIYHMHRSKKIWGPDAETFNPDHFLPHNIQ-DKHP 411 Query: 318 NALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLS 202 A + F+ G R+CIG +A+I AK +A +L+ + F S Sbjct: 412 YAYIPFTKGIRNCIGWRYALISAKVTLAKLLRNYRFKTS 450
>CP3AP_MOUSE (O09158) Cytochrome P450 3A25 (EC 1.14.14.1) (CYPIIIA25)| Length = 503 Score = 75.9 bits (185), Expect = 6e-14 Identities = 37/94 (39%), Positives = 55/94 (58%) Frame = -3 Query: 495 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPN 316 ++R + D+E+ G+ +PKGTV+ IPI +HR+ E W E EF P RF + P Sbjct: 373 LERVSKKDVEINGVFIPKGTVVMIPIYPLHRNPEYWPE-PQEFCPERFSK-ENKGNIDPY 430 Query: 315 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFS 214 + F +GPR+CIG FA+I K + +LQ F+ Sbjct: 431 IYMPFGNGPRNCIGMRFALISIKLAVIGVLQNFT 464
>CP4A7_RABIT (P14581) Cytochrome P450 4A7 precursor (EC 1.14.15.3) (CYPIVA7)| (Lauric acid omega-hydroxylase) (P450-KA-2) Length = 511 Score = 75.9 bits (185), Expect = 6e-14 Identities = 43/112 (38%), Positives = 61/112 (54%) Frame = -3 Query: 459 GIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPNALLSFSSGPRSC 280 G +PKG +IT+ I +H + +VW + F P RF G R H +A L FS G R+C Sbjct: 403 GRSLPKGIIITLSIYGLHHNPKVW-PNPEVFDPSRFAPGSAR---HSHAFLPFSGGSRNC 458 Query: 279 IGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITLRPKFGLPMILKSL 124 IG+ FAM E K +A+ L RF P V P+ + L+ K G+ + L+ L Sbjct: 459 IGKQFAMNELKVAVALTLVRFELLPDPTRVPIPITRLVLKSKNGIHLRLRKL 510
>CP3AF_CAVPO (Q64406) Cytochrome P450 3A15 (EC 1.14.14.1) (CYPIIIA15)| Length = 503 Score = 75.5 bits (184), Expect = 8e-14 Identities = 36/95 (37%), Positives = 55/95 (57%) Frame = -3 Query: 495 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPN 316 I+R + D E+ G+ PKGT++ IP +HRD + W E +EF+P RF + P Sbjct: 373 IERMSKKDFEINGMSFPKGTLVMIPSFALHRDSKYWPE-PDEFRPERFSK-KNKENIDPY 430 Query: 315 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSF 211 + F +GPR+CIG+ A++ K + +LQ FSF Sbjct: 431 IYMPFGNGPRNCIGRRMALMNLKLALIRLLQNFSF 465
>C13A3_CAEEL (Q27517) Putative cytochrome P450 CYP13A3 (EC 1.14.-.-)| Length = 520 Score = 75.5 bits (184), Expect = 8e-14 Identities = 41/107 (38%), Positives = 62/107 (57%) Frame = -3 Query: 489 RKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPNAL 310 RK V G+K+ +GT + T+H D + WGE+ANEFKP R+E+G +A A Sbjct: 396 RKCMKSTTVLGMKIEEGTNVQADTWTLHYDPKFWGENANEFKPERWESGDEQA-VAKGAY 454 Query: 309 LSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVI 169 L F GPR CIG A +E K ++A IL+++S + + H P+ ++ Sbjct: 455 LPFGLGPRICIGMRLAYMEEKMLLAQILKKYSLETTFE-THIPLKLV 500
>CP4C3_DROME (Q9VA27) Cytochrome P450 4c3 (EC 1.14.-.-) (CYPIVC3)| Length = 535 Score = 75.1 bits (183), Expect = 1e-13 Identities = 46/118 (38%), Positives = 69/118 (58%), Gaps = 3/118 (2%) Frame = -3 Query: 489 RKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRF--ENGVTRAGKHPN 316 R G D+ +GG VP GT I +HR+ V+ + +F P F EN AG+HP Sbjct: 414 RMVGEDVNIGGKIVPAGTQAIIMTYALHRNPRVFPKP-EQFNPDNFLPENC---AGRHPF 469 Query: 315 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSF-SLSPKYVHAPMDVITLRPKFGL 145 A + FS+GPR+CIGQ FA++E KAVI+ +L+++ ++ + + + LRPK GL Sbjct: 470 AYIPFSAGPRNCIGQKFAILEEKAVISTVLRKYKIEAVDRREDLTLLGELILRPKDGL 527
>CP3A2_RAT (P05183) Cytochrome P450 3A2 (EC 1.14.14.1) (CYPIIIA2) (P450-PCN2)| (P450/6-beta-A) (Testosterone 6-beta-hydroxylase) Length = 504 Score = 75.1 bits (183), Expect = 1e-13 Identities = 36/95 (37%), Positives = 54/95 (56%) Frame = -3 Query: 495 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPN 316 ++R D+E+ G+ +PKG+V+TIP +H D + W + EF P RF + P Sbjct: 374 LERVCKKDIELDGLFIPKGSVVTIPTYALHHDPQHWPKP-EEFHPERFSKE-NKGSIDPY 431 Query: 315 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSF 211 L F +GPR+CIG FA++ K + +LQ FSF Sbjct: 432 VYLPFGNGPRNCIGMRFALMNMKLALTKVLQNFSF 466
>CP4D1_DROME (P33269) Cytochrome P450 4d1 (EC 1.14.-.-) (CYPIVD1)| Length = 512 Score = 75.1 bits (183), Expect = 1e-13 Identities = 44/123 (35%), Positives = 66/123 (53%) Frame = -3 Query: 489 RKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPNAL 310 RK D E+ G +P GT I I + R +E++ E N FKP RF+ T +P A Sbjct: 388 RKVLEDCEINGKLIPAGTNIGISPLYLGRREELFSEP-NSFKPERFDVVTTAEKLNPYAY 446 Query: 309 LSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITLRPKFGLPMILK 130 + FS+GPR+CIGQ FAM+E KA++A +L+ + P+ + L + P++ K Sbjct: 447 IPFSAGPRNCIGQKFAMLEIKAIVANVLRHYEVDFVGDSSEPPVLIAELILRTKEPLMFK 506 Query: 129 SLE 121 E Sbjct: 507 VRE 509
>CP4D1_DROSI (O16805) Cytochrome P450 4d1 (EC 1.14.-.-) (CYPIVD1)| Length = 512 Score = 74.7 bits (182), Expect = 1e-13 Identities = 44/123 (35%), Positives = 66/123 (53%) Frame = -3 Query: 489 RKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPNAL 310 RK D E+ G +P GT I I + R +E++ E N FKP RF+ T +P A Sbjct: 388 RKVLEDCEINGKLIPAGTNIGISPLYLGRREELFSEP-NSFKPERFDVVTTAEKLNPYAY 446 Query: 309 LSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITLRPKFGLPMILK 130 + FS+GPR+CIGQ FAM+E KA++A +L+ + P+ + L + P++ K Sbjct: 447 IPFSAGPRNCIGQKFAMLEIKAIVANVLRHYEVDFVGDSSEPPVLIAELILRTKDPLMFK 506 Query: 129 SLE 121 E Sbjct: 507 VRE 509
>CP132_MYCTU (P77900) Putative cytochrome P450 132 (EC 1.14.-.-)| Length = 461 Score = 74.7 bits (182), Expect = 1e-13 Identities = 47/121 (38%), Positives = 68/121 (56%), Gaps = 1/121 (0%) Frame = -3 Query: 495 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPN 316 I R+A D + G ++ +GT + IPI IH D W D + F P RF T + Sbjct: 341 IAREAVDDDIIDGHRIRRGTTVVIPIHHIHHDPR-WWPDPDRFDPGRFLRCPTDRPRC-- 397 Query: 315 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMD-VITLRPKFGLPM 139 A L F G R CIGQ+FA++E + A++ Q F+F L+P Y H ++ +TLRPK G+ + Sbjct: 398 AYLPFGGGRRICIGQSFALMEMVLMAAIMSQHFTFDLAPGY-HVELEATLTLRPKHGVHV 456 Query: 138 I 136 I Sbjct: 457 I 457
>CP132_MYCBO (P59954) Putative cytochrome P450 132 (EC 1.14.-.-)| Length = 461 Score = 74.7 bits (182), Expect = 1e-13 Identities = 47/121 (38%), Positives = 68/121 (56%), Gaps = 1/121 (0%) Frame = -3 Query: 495 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPN 316 I R+A D + G ++ +GT + IPI IH D W D + F P RF T + Sbjct: 341 IAREAVDDDIIDGHRIRRGTTVVIPIHHIHHDPR-WWPDPDRFDPGRFLRCPTDRPRC-- 397 Query: 315 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMD-VITLRPKFGLPM 139 A L F G R CIGQ+FA++E + A++ Q F+F L+P Y H ++ +TLRPK G+ + Sbjct: 398 AYLPFGGGRRICIGQSFALMEMVLMAAIMSQHFTFDLAPGY-HVELEATLTLRPKHGVHV 456 Query: 138 I 136 I Sbjct: 457 I 457
>C13A7_CAEEL (Q27519) Putative cytochrome P450 CYP13A7 (EC 1.14.-.-)| Length = 518 Score = 74.3 bits (181), Expect = 2e-13 Identities = 38/100 (38%), Positives = 56/100 (56%) Frame = -3 Query: 489 RKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPNAL 310 RK V G+++ GT I + ++H D +VWG+D NEFKP R+E+G Sbjct: 396 RKCLKTTNVLGMEIEAGTNINVDTWSLHHDPKVWGDDVNEFKPERWESG-DELFFAKGGY 454 Query: 309 LSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYV 190 L F GPR CIG AM+E K ++ IL+ ++F +P+ V Sbjct: 455 LPFGMGPRICIGMRLAMMEMKMLLTNILKNYTFETTPETV 494
>CP3AV_MESAU (O70537) Cytochrome P450 3A31 (EC 1.14.14.1) (CYPIIIA31) (P450| SH3A-1) Length = 501 Score = 74.3 bits (181), Expect = 2e-13 Identities = 44/126 (34%), Positives = 70/126 (55%), Gaps = 4/126 (3%) Frame = -3 Query: 495 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPN 316 ++R D+E+ G+ VPKG+++ +P+ +H D + W E +F+P RF + P Sbjct: 371 LERVCKQDVEMDGVFVPKGSIVMVPVFALHYDPQYWPEP-EKFRPERFSKE-NKGSIDPY 428 Query: 315 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSP-KYVHAPMDV---ITLRPKFG 148 L F +GPR+CIG FA++ K + +LQ +FSL P K PM + L+P+ Sbjct: 429 IFLPFGNGPRNCIGMRFALMNMKLALTKVLQ--NFSLQPCKETQIPMKLSRKAMLQPE-- 484 Query: 147 LPMILK 130 P+ILK Sbjct: 485 KPIILK 490
>CP4V2_PONPY (Q5RCN6) Cytochrome P450 4V2 (EC 1.14.-.-)| Length = 525 Score = 74.3 bits (181), Expect = 2e-13 Identities = 47/123 (38%), Positives = 68/123 (55%), Gaps = 3/123 (2%) Frame = -3 Query: 489 RKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRF--ENGVTRAGKHPN 316 R D EV G +V KGT I +HRD + + EF+P RF EN G+HP Sbjct: 400 RSVSEDCEVAGYRVLKGTEAVIIPYALHRDPRYF-PNPEEFQPERFFPENA---QGRHPY 455 Query: 315 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMD-VITLRPKFGLPM 139 A + FS+GPR+CIGQ FA++E K +++ IL+ F + K ++ + LRP G+ + Sbjct: 456 AYVPFSAGPRNCIGQKFAVMEEKTILSCILRHFWIESNQKREELGLEGQLILRPSNGIWI 515 Query: 138 ILK 130 LK Sbjct: 516 KLK 518
>CP4V2_HUMAN (Q6ZWL3) Cytochrome P450 4V2 (EC 1.14.-.-)| Length = 525 Score = 74.3 bits (181), Expect = 2e-13 Identities = 47/123 (38%), Positives = 68/123 (55%), Gaps = 3/123 (2%) Frame = -3 Query: 489 RKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRF--ENGVTRAGKHPN 316 R D EV G +V KGT I +HRD + + EF+P RF EN G+HP Sbjct: 400 RSVSEDCEVAGYRVLKGTEAVIIPYALHRDPRYF-PNPEEFQPERFFPENA---QGRHPY 455 Query: 315 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMD-VITLRPKFGLPM 139 A + FS+GPR+CIGQ FA++E K +++ IL+ F + K ++ + LRP G+ + Sbjct: 456 AYVPFSAGPRNCIGQKFAVMEEKTILSCILRHFWIESNQKREELGLEGQLILRPSNGIWI 515 Query: 138 ILK 130 LK Sbjct: 516 KLK 518
>C340_ORYLA (Q98T91) Cytochrome P450 3A40 (EC 1.14.14.1)| Length = 502 Score = 73.9 bits (180), Expect = 2e-13 Identities = 37/99 (37%), Positives = 57/99 (57%) Frame = -3 Query: 501 AAIQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKH 322 A ++R A + +EV G+ +PK V+ +P +HRD E+W E +FKP RF + Sbjct: 372 ARLERVAKATVEVNGLVIPKDMVVMVPTWPLHRDPELWPEP-EKFKPERFSKE-NKDTFD 429 Query: 321 PNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSL 205 P + F +GPR+CIG FA++ K + ILQ + FS+ Sbjct: 430 PYTYMPFGAGPRNCIGMRFALVMMKLAVVEILQTYDFSV 468
>C13A8_CAEEL (Q27516) Putative cytochrome P450 CYP13A8 (EC 1.14.-.-)| Length = 509 Score = 73.9 bits (180), Expect = 2e-13 Identities = 41/118 (34%), Positives = 66/118 (55%), Gaps = 3/118 (2%) Frame = -3 Query: 498 AIQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHP 319 A R+ + +G V G + I T+H DK VWG D EFKP R+++ +T Sbjct: 387 ANSRRCMRNTVIGEQIVEAGVDVMIDTWTLHHDKNVWGNDVEEFKPERWDSPLTPQ---- 442 Query: 318 NALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVI---TLRPK 154 A LSF +GPR C+G FA++E K +++ IL++++F + K P+ ++ T RP+ Sbjct: 443 QAYLSFGAGPRVCLGMRFALLEQKGLLSHILKKYTFETNAK-TQLPIKLVGRATARPE 499
>CP3AH_CAVPO (Q64409) Cytochrome P450 3A17 (EC 1.14.14.1) (CYPIIIA17)| Length = 503 Score = 73.9 bits (180), Expect = 2e-13 Identities = 44/125 (35%), Positives = 67/125 (53%), Gaps = 3/125 (2%) Frame = -3 Query: 495 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPN 316 I+R + D E+ G+ PKGT + IP +HRD + W E +EF+P RF + P Sbjct: 373 IERMSKKDFEINGMSFPKGTGVMIPSFALHRDSKYWPE-PDEFRPERFSK-KNKENIDPY 430 Query: 315 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDV---ITLRPKFGL 145 + F +GPR+CIG A++ K + +LQ FSF + K P+ + + L+P Sbjct: 431 IYMPFGNGPRNCIGMRMALMNLKLALIRLLQNFSF-YTCKETQIPLRLGSQVILQP--AK 487 Query: 144 PMILK 130 P+ILK Sbjct: 488 PIILK 492
>C13A4_CAEEL (Q27513) Putative cytochrome P450 CYP13A4 (EC 1.14.-.-)| Length = 520 Score = 73.9 bits (180), Expect = 2e-13 Identities = 37/96 (38%), Positives = 55/96 (57%) Frame = -3 Query: 489 RKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPNAL 310 RK V G+++ +GT + + T+H D +VWG+DA+EFKP R+E G Sbjct: 396 RKCMKKTNVLGVEIDEGTNVQVDTWTLHYDPKVWGDDASEFKPERWETG-DELFYAKGGY 454 Query: 309 LSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLS 202 L F GPR CIG AM+E K ++ IL++++F S Sbjct: 455 LPFGMGPRICIGMRLAMMEEKLLLTHILKKYTFDTS 490
>CP4A6_RABIT (P14580) Cytochrome P450 4A6 precursor (EC 1.14.15.3) (CYPIVA6)| (Lauric acid omega-hydroxylase) (P450-KA-1) Length = 510 Score = 73.6 bits (179), Expect = 3e-13 Identities = 41/112 (36%), Positives = 59/112 (52%) Frame = -3 Query: 459 GIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPNALLSFSSGPRSC 280 G +PKG ++T+ I +H + +VW + F P F G R H +A L FS GPR+C Sbjct: 402 GRSLPKGVIVTLSIYALHHNPKVW-PNPEVFDPFPFAPGSAR---HSHAFLPFSGGPRNC 457 Query: 279 IGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITLRPKFGLPMILKSL 124 IG+ FAM E K +A+ L RF PK V + L+ G+ + L+ L Sbjct: 458 IGKQFAMNELKVAVALTLVRFELLPDPKRVPDQKPRLVLKSSNGIHLRLRKL 509
>CP3AB_MOUSE (Q64459) Cytochrome P450 3A11 (EC 1.14.14.1) (CYPIIIA11)| (P-450IIIAM1) (P-450UT) Length = 504 Score = 73.6 bits (179), Expect = 3e-13 Identities = 34/95 (35%), Positives = 53/95 (55%) Frame = -3 Query: 495 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPN 316 ++R D+E+ G+ +PKG+ + IP +H D + W E EF+P RF + P Sbjct: 374 LERVCKKDVELNGVYIPKGSTVMIPSYALHHDPQHWSEP-EEFQPERFSKE-NKGSIDPY 431 Query: 315 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSF 211 L F +GPR+C+G FA++ K + I+Q FSF Sbjct: 432 VYLPFGNGPRNCLGMRFALMNMKLALTKIMQNFSF 466
>CP3AE_CAVPO (Q64417) Cytochrome P450 3A14 (EC 1.14.14.1) (CYPIIIA14)| Length = 503 Score = 73.6 bits (179), Expect = 3e-13 Identities = 36/95 (37%), Positives = 53/95 (55%) Frame = -3 Query: 495 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPN 316 I+R + D E+ G+ PKGT + IP +HRD + W E +EF+P RF + P Sbjct: 373 IERMSKKDFEINGMSFPKGTGVMIPSFALHRDSKYWPE-PDEFRPERFSK-KNKENIDPY 430 Query: 315 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSF 211 + F +GPR+CIG A++ K + +LQ FSF Sbjct: 431 IYMPFGNGPRNCIGMRMALMNLKLALIRLLQNFSF 465
>CP3A5_HUMAN (P20815) Cytochrome P450 3A5 (EC 1.14.14.1) (CYPIIIA5) (P450-PCN3)| (HLp2) Length = 502 Score = 73.6 bits (179), Expect = 3e-13 Identities = 42/125 (33%), Positives = 67/125 (53%), Gaps = 3/125 (2%) Frame = -3 Query: 495 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPN 316 ++R D+E+ G+ +PKG+++ IP +H D + W E EF+P RF + P Sbjct: 373 LERTCKKDVEINGVFIPKGSMVVIPTYALHHDPKYWTEP-EEFRPERFSK--KKDSIDPY 429 Query: 315 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVIT---LRPKFGL 145 F +GPR+CIG FA++ K + +LQ FSF K P+ + T L+P+ Sbjct: 430 IYTPFGTGPRNCIGMRFALMNMKLALIRVLQNFSFK-PCKETQIPLKLDTQGLLQPE--K 486 Query: 144 PMILK 130 P++LK Sbjct: 487 PIVLK 491
>CP131_DROME (Q9VFJ0) Probable cytochrome P450 313a1 (EC 1.14.-.-)| (CYPCCCXIIIA1) Length = 492 Score = 73.2 bits (178), Expect = 4e-13 Identities = 40/102 (39%), Positives = 58/102 (56%), Gaps = 3/102 (2%) Frame = -3 Query: 489 RKAGSDLEVG-GIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRF--ENGVTRAGKHP 319 R+ +D+ + G+ +PKG VI I + HR+ EVWG DA+ F P F EN KHP Sbjct: 369 RETKNDVRLSNGVLIPKGVVIGIDMFHTHRNPEVWGPDADNFNPDNFLAEN---MEQKHP 425 Query: 318 NALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKY 193 A + F+ G R+CIG +AM+ +K + IL+ + S S Y Sbjct: 426 YAYIPFARGKRNCIGSKYAMMSSKFALCRILRNYKISTSTLY 467
>CP3A6_RABIT (P11707) Cytochrome P450 3A6 (EC 1.14.14.1) (CYPIIIA6) (P450-3C)| Length = 501 Score = 72.8 bits (177), Expect = 5e-13 Identities = 33/97 (34%), Positives = 56/97 (57%) Frame = -3 Query: 495 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPN 316 ++R D+++ G +PKGT++ +P +HRD + W E +EF+P RF + +P Sbjct: 371 LERVCKKDVDINGTFIPKGTIVMMPTYALHRDPQHWTEP-DEFRPERFSKK-NKDNINPY 428 Query: 315 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSL 205 F +GPR+C+G FA++ K + ++Q FSF L Sbjct: 429 IYHPFGAGPRNCLGMRFALMNIKLALVRLMQNFSFKL 465
>CP4AA_RAT (P08516) Cytochrome P450 4A10 (EC 1.14.15.3) (CYPIVA10) (Lauric| acid omega-hydroxylase) (P450-LA-omega 1) (P452) Length = 509 Score = 72.8 bits (177), Expect = 5e-13 Identities = 41/112 (36%), Positives = 60/112 (53%) Frame = -3 Query: 459 GIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPNALLSFSSGPRSC 280 G +PKG +T+ I +H + +VW + F P RF R H ++ L FS G R+C Sbjct: 401 GRSLPKGIQVTLSIYGLHHNPKVW-PNPEVFDPSRFAPDSPR---HSHSFLPFSGGARNC 456 Query: 279 IGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITLRPKFGLPMILKSL 124 IG+ FAM E K ++A+ L RF P V P+ + L+ K G+ + LK L Sbjct: 457 IGKQFAMSEMKVIVALTLLRFELLPDPTKVPIPLPRLVLKSKNGIYLYLKKL 508
>C13A1_CAEEL (Q27520) Putative cytochrome P450 CYP13A1 (EC 1.14.-.-)| Length = 519 Score = 72.8 bits (177), Expect = 5e-13 Identities = 34/101 (33%), Positives = 56/101 (55%) Frame = -3 Query: 498 AIQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHP 319 A R+ + ++G +KV GT+I + T+H D +WG+DA +FKP R++ + Sbjct: 393 ANSRRCMRNTKLGNMKVEVGTMIQVDTWTLHTDPNIWGDDAEDFKPERWQTPNSDQIYQK 452 Query: 318 NALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPK 196 + + F GPR CIG A +E K ++ IL++F+F K Sbjct: 453 SGYIPFGLGPRQCIGMRLAYMEEKILLVHILRKFTFETGAK 493
>CP4CU_BLAGE (Q964T1) Cytochrome P450 4c21 (EC 1.14.14.1) (CYPIVC21)| Length = 501 Score = 72.0 bits (175), Expect = 8e-13 Identities = 37/97 (38%), Positives = 57/97 (58%), Gaps = 4/97 (4%) Frame = -3 Query: 489 RKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGE----DANEFKPMRFENGVTRAGKH 322 R+A D E+GG +P GT I + IHR+ E++ + + F P R N +H Sbjct: 380 REAHQDFELGGYTIPAGTNIDFSVPFIHRNPEIFPNPRCFNPDNFLPDRVVN------RH 433 Query: 321 PNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSF 211 P A + FS+GPR+CIGQ FA++E K V++ +L+ + F Sbjct: 434 PYAYIPFSAGPRNCIGQRFALLEEKVVLSYLLRHYRF 470
>CP4AA_MOUSE (O88833) Cytochrome P450 4A10 (EC 1.14.15.3) (CYPIVA10) (Lauric| acid omega-hydroxylase) (P450-LA-omega 1) (P452) Length = 509 Score = 72.0 bits (175), Expect = 8e-13 Identities = 41/112 (36%), Positives = 60/112 (53%) Frame = -3 Query: 459 GIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPNALLSFSSGPRSC 280 G +PKG +T+ I +H + +VW + F P RF R H ++ L FS G R+C Sbjct: 401 GRSLPKGVQVTLSIYGLHHNPKVW-PNPEVFDPSRFAPDSPR---HSHSFLPFSGGARNC 456 Query: 279 IGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITLRPKFGLPMILKSL 124 IG+ FAM E K ++A+ L RF P V P+ + L+ K G+ + LK L Sbjct: 457 IGKQFAMSELKVIVALTLLRFELLPDPTRVPMPLARLVLKSKNGIYLHLKKL 508
>CP3A4_HUMAN (P08684) Cytochrome P450 3A4 (EC 1.14.13.67) (Quinine| 3-monooxygenase) (CYPIIIA4) (Nifedipine oxidase) (Taurochenodeoxycholate 6-alpha-hydroxylase) (EC 1.14.13.97) (NF-25) (P450-PCN1) Length = 502 Score = 71.2 bits (173), Expect = 1e-12 Identities = 36/95 (37%), Positives = 52/95 (54%) Frame = -3 Query: 495 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPN 316 ++R D+E+ G+ +PKG V+ IP +HRD + W E +F P RF + P Sbjct: 372 LERVCKKDVEINGMFIPKGWVVMIPSYALHRDPKYWTEP-EKFLPERFSKK-NKDNIDPY 429 Query: 315 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSF 211 F SGPR+CIG FA++ K + +LQ FSF Sbjct: 430 IYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSF 464
>CP4A2_RAT (P20816) Cytochrome P450 4A2 precursor (EC 1.14.15.3) (CYPIVA2)| (Lauric acid omega-hydroxylase) (P450-LA-omega 2) (P450 K-5) (P-450 K-2) Length = 504 Score = 71.2 bits (173), Expect = 1e-12 Identities = 42/112 (37%), Positives = 57/112 (50%) Frame = -3 Query: 459 GIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPNALLSFSSGPRSC 280 G +PKG +TI I +H + W + F P RF R H +A L FS G R+C Sbjct: 396 GRSIPKGIRVTILIYGLHHNPSYW-PNPKVFDPSRFSPDSPR---HSHAYLPFSGGARNC 451 Query: 279 IGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITLRPKFGLPMILKSL 124 IG+ FAM E K +A+ L RF P + PM + L+ K G+ + LK L Sbjct: 452 IGKQFAMNELKVAVALTLLRFELLPDPTRIPVPMPRLVLKSKNGIHLRLKKL 503
>CP4X1_HUMAN (Q8N118) Cytochrome P450 4X1 (EC 1.14.14.1) (CYPIVX1)| Length = 509 Score = 71.2 bits (173), Expect = 1e-12 Identities = 45/114 (39%), Positives = 61/114 (53%), Gaps = 2/114 (1%) Frame = -3 Query: 459 GIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRF--ENGVTRAGKHPNALLSFSSGPR 286 G +P G + + I +H + VW ++ F P+RF EN R HP A L FS+G R Sbjct: 397 GCTLPAGITVVLSIWGLHHNPAVW-KNPKVFDPLRFSQENSDQR---HPYAYLPFSAGSR 452 Query: 285 SCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITLRPKFGLPMILKSL 124 +CIGQ FAMIE K IA+IL F + P + L+PK G+ + LK L Sbjct: 453 NCIGQEFAMIELKVTIALILLHFRVTPDPTRPLTFPNHFILKPKNGMYLHLKKL 506
>CP3A8_MACFA (P33268) Cytochrome P450 3A8 (EC 1.14.14.1) (CYPIIIA8) (P450-MKNF2)| (P-450-MK2) Length = 503 Score = 71.2 bits (173), Expect = 1e-12 Identities = 37/95 (38%), Positives = 50/95 (52%) Frame = -3 Query: 495 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPN 316 ++R D+E+ GI +PKG V+ IP +H D + W E +F P RF P Sbjct: 373 LERVCKKDVEINGIFIPKGVVVMIPSYALHHDPKYWPEP-EKFLPERFSKK-NNDNIDPY 430 Query: 315 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSF 211 F SGPR+CIG FA++ K I +LQ FSF Sbjct: 431 IYTPFGSGPRNCIGMRFALMNMKLAIIRVLQNFSF 465
>CP3A7_HUMAN (P24462) Cytochrome P450 3A7 (EC 1.14.14.1) (CYPIIIA7) (P450-HFLA)| Length = 503 Score = 71.2 bits (173), Expect = 1e-12 Identities = 35/95 (36%), Positives = 51/95 (53%) Frame = -3 Query: 495 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPN 316 ++R D+E+ G+ +PKG V+ IP +H D + W E +F P RF + P Sbjct: 373 LERVCKKDVEINGMFIPKGVVVMIPSYVLHHDPKYWREP-EKFLPERFSKK-NKDNIDPY 430 Query: 315 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSF 211 F SGPR+CIG FA++ K + +LQ FSF Sbjct: 431 IYTPFGSGPRNCIGMRFALVNMKLALVRVLQNFSF 465
>CP3A3_HUMAN (P05184) Cytochrome P450 3A3 (EC 1.14.14.1) (CYPIIIA3) (HLp)| Length = 503 Score = 71.2 bits (173), Expect = 1e-12 Identities = 36/95 (37%), Positives = 52/95 (54%) Frame = -3 Query: 495 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPN 316 ++R D+E+ G+ +PKG V+ IP +HRD + W E +F P RF + P Sbjct: 373 LERVCKKDVEINGMFIPKGWVVMIPSYALHRDPKYWTEP-EKFLPERFSKK-NKDNIDPY 430 Query: 315 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSF 211 F SGPR+CIG FA++ K + +LQ FSF Sbjct: 431 IYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSF 465
>CP4AC_MOUSE (Q91WL5) Cytochrome P450 4A12 (EC 1.14.14.1) (CYPIVA12)| Length = 508 Score = 70.5 bits (171), Expect = 2e-12 Identities = 41/113 (36%), Positives = 59/113 (52%) Frame = -3 Query: 459 GIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPNALLSFSSGPRSC 280 G +PKG + + +H + VW + F P RF G +R H ++ L FS G R+C Sbjct: 400 GRSLPKGIHVMLSFYGLHHNPTVW-PNPEVFDPSRFAPGSSR---HSHSFLPFSGGARNC 455 Query: 279 IGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITLRPKFGLPMILKSLE 121 IG+ FAM E K +A+ L RF P V P+ I L+ K G+ + LK L+ Sbjct: 456 IGKQFAMNELKVAVALTLLRFELLPDPTRVPIPIPRIVLKSKNGIHLHLKKLQ 508
>C4D10_DROMT (O18596) Cytochrome P450 4d10 (EC 1.14.-.-) (CYPIVD10)| Length = 513 Score = 70.5 bits (171), Expect = 2e-12 Identities = 40/120 (33%), Positives = 65/120 (54%) Frame = -3 Query: 489 RKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPNAL 310 RK + E+ G +P GT I I + R +++ E N FKP RF+ + +P+A Sbjct: 389 RKVLQECEINGKIIPAGTNIGISPLFLGRSEDISSEP-NTFKPERFDVVTSAEKLNPHAY 447 Query: 309 LSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITLRPKFGLPMILK 130 + FS+GPR+CIGQ FAM+E KA+ A +L+ + +P+ + L + P++ K Sbjct: 448 IPFSAGPRNCIGQKFAMLEIKAIAANVLRHYEIEFVGNAEESPVLIAELILRTKDPLMFK 507
>THAS_MOUSE (P36423) Thromboxane-A synthase (EC 5.3.99.5) (TXA synthase) (TXS)| (TS) Length = 533 Score = 70.5 bits (171), Expect = 2e-12 Identities = 36/98 (36%), Positives = 51/98 (52%) Frame = -3 Query: 489 RKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPNAL 310 R+A D EV G ++P GTV+ I + +H D E W + F P RF R + P Sbjct: 412 REAAQDCEVLGQRIPAGTVLEIAVGALHHDPEHW-PNPETFDPERF-TAEARLQRRPFTY 469 Query: 309 LSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPK 196 L F +GPRSC+G ++ K I +L +F F SP+ Sbjct: 470 LPFGAGPRSCLGVRLGLLVVKLTILQVLHKFRFEASPE 507
>C13A2_CAEEL (Q27518) Putative cytochrome P450 CYP13A2 (EC 1.14.-.-)| Length = 515 Score = 70.5 bits (171), Expect = 2e-12 Identities = 34/98 (34%), Positives = 51/98 (52%) Frame = -3 Query: 489 RKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPNAL 310 RK V G+K+ G + + ++H D E+WGED EFKP R+ +H A Sbjct: 393 RKCMKTTTVNGVKIEAGVYVQMDTWSLHYDPELWGEDVKEFKPERW--STDEPLEHKGAY 450 Query: 309 LSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPK 196 L F GPR CIG A++E K ++ +L+ ++F K Sbjct: 451 LPFGLGPRQCIGMRLAIMEQKILLTHLLKNYTFETGNK 488
>CP3AA_MESAU (Q64148) Cytochrome P450 3A10 (EC 1.14.13.94) (CYPIIIA10)| (Lithocholate 6-beta-hydroxylase) (6 beta-hydroxylase) Length = 503 Score = 70.5 bits (171), Expect = 2e-12 Identities = 32/94 (34%), Positives = 52/94 (55%) Frame = -3 Query: 495 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPN 316 ++R + +E+ G+ +PKG + +P +HRD E W E EF+P RF + P Sbjct: 373 LERISKKAVEINGLFIPKGITVMVPTYPLHRDPEYWPEP-EEFRPERFSKE-NKGSIDPY 430 Query: 315 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFS 214 + F +GPR+CIG FA++ K + +LQ F+ Sbjct: 431 VYMPFGNGPRNCIGMRFALLSMKLAVVSVLQNFT 464
>C13AA_CAEEL (Q09653) Putative cytochrome P450 CYP13A10 (EC 1.14.-.-)| Length = 519 Score = 70.5 bits (171), Expect = 2e-12 Identities = 32/101 (31%), Positives = 57/101 (56%) Frame = -3 Query: 498 AIQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHP 319 A R+ ++G ++V GT++ + ++H D ++WG+DA EFKP R+ + Sbjct: 393 ANSRRCMRATKLGNVEVEVGTMVQVDTWSLHTDTKIWGDDAKEFKPERWLDPNCDQVFQK 452 Query: 318 NALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPK 196 +SF GPR C+G A +E K ++A IL++++F + K Sbjct: 453 GGYISFGLGPRQCVGMRLAYMEEKMLLAHILRKYTFEVGTK 493
>CP4AE_RAT (P20817) Cytochrome P450 4A14 precursor (EC 1.14.15.3) (CYPIVA14)| (Lauric acid omega-hydroxylase) (P450-LA-omega 3) Length = 507 Score = 70.5 bits (171), Expect = 2e-12 Identities = 42/112 (37%), Positives = 56/112 (50%) Frame = -3 Query: 459 GIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPNALLSFSSGPRSC 280 G +PKG TI I +H + W + F P RF R H +A L FS G R+C Sbjct: 399 GRSIPKGITTTILIYGLHHNPSYW-PNPKVFDPSRFSPDSPR---HSHAYLPFSGGARNC 454 Query: 279 IGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITLRPKFGLPMILKSL 124 IG+ FAM E K +A+ L RF P + PM + L+ K G+ + LK L Sbjct: 455 IGKQFAMNELKVAVALTLLRFELLPDPTRIPVPMARLVLKSKNGIHLRLKKL 506
>CP4A5_RABIT (P14579) Cytochrome P450 4A5 precursor (EC 1.14.15.3) (CYPIVA5)| (Lauric acid omega-hydroxylase) Length = 511 Score = 70.1 bits (170), Expect = 3e-12 Identities = 40/113 (35%), Positives = 58/113 (51%) Frame = -3 Query: 459 GIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPNALLSFSSGPRSC 280 G +PKG +T+ I +H + VW + F P RF G R H +A L FS G R+C Sbjct: 403 GRSLPKGFTVTLSIYGLHHNPNVW-PNPEVFDPGRFTPGSAR---HSHAFLPFSGGARNC 458 Query: 279 IGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITLRPKFGLPMILKSLE 121 IG+ FAM E K +A+ L RF P + P + L+ G+ + L+ L+ Sbjct: 459 IGKQFAMNELKVAVALTLVRFELLPDPTRIPKPTARLVLKSNNGIHLRLRKLQ 511
>CP4AE_MOUSE (O35728) Cytochrome P450 4A14 precursor (EC 1.14.15.3) (CYPIVA14)| (Lauric acid omega-hydroxylase 3) (P450-LA-omega 3) Length = 507 Score = 69.7 bits (169), Expect = 4e-12 Identities = 40/112 (35%), Positives = 56/112 (50%) Frame = -3 Query: 459 GIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPNALLSFSSGPRSC 280 G +PKG TI I +H + W + F P RF + H +A L FS G R+C Sbjct: 399 GRSIPKGITATISIYGLHHNPRFW-PNPKVFDPSRF---APDSSHHSHAYLPFSGGSRNC 454 Query: 279 IGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITLRPKFGLPMILKSL 124 IG+ FAM E K +A+ L RF P + P+ + L+ K G+ + LK L Sbjct: 455 IGKQFAMNELKVAVALTLLRFELLPDPTRIPVPIARLVLKSKNGIHLCLKKL 506
>CP3AL_CALJA (O18993) Cytochrome P450 3A21 (EC 1.14.14.1) (CYPIIIA21) (P450| CM3A-10) Length = 503 Score = 69.7 bits (169), Expect = 4e-12 Identities = 34/95 (35%), Positives = 51/95 (53%) Frame = -3 Query: 495 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPN 316 ++R D+E+ G+ +PKG V+ IP +H D + W E +F P RF + P Sbjct: 373 LERVCKKDVEINGVFIPKGVVVMIPSYALHYDPKYWTEP-EKFLPERFSKN-NKDNIDPY 430 Query: 315 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSF 211 F +GPR+CIG FA++ K + +LQ FSF Sbjct: 431 IYTPFGTGPRNCIGMRFALMNMKLALIRVLQNFSF 465
>CP52J_CANMA (Q12588) Cytochrome P450 52A10 (EC 1.14.14.-) (CYPLIIA10)| (Alkane-inducible P450-ALK7) Length = 519 Score = 69.7 bits (169), Expect = 4e-12 Identities = 39/94 (41%), Positives = 57/94 (60%), Gaps = 2/94 (2%) Frame = -3 Query: 456 IKVPKGTVITIPIATIHRDKEVWGEDANEFKPMR-FENGVTRAGKHPNALLSFSSGPRSC 280 I V KG + + + RD++ +G+DANEF+P R FE V + G A L F+ GPR C Sbjct: 410 ILVRKGQTVMYSVYALQRDEKYYGKDANEFRPERWFEPEVRKLGW---AFLPFNGGPRIC 466 Query: 279 IGQNFAMIEAKAVIAMILQRF-SFSLSPKYVHAP 181 +GQ FA+ EA V+A ++Q F + LSP+ + P Sbjct: 467 LGQQFALTEASYVLARLIQSFETLELSPEAAYPP 500
>CP4AB_HUMAN (Q02928) Cytochrome P450 4A11 precursor (EC 1.14.15.3) (CYPIVA11)| (Fatty acid omega-hydroxylase) (P-450 HK omega) (Lauric acid omega-hydroxylase) (CYP4AII) (P450-HL-omega) Length = 519 Score = 69.7 bits (169), Expect = 4e-12 Identities = 39/112 (34%), Positives = 60/112 (53%) Frame = -3 Query: 459 GIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPNALLSFSSGPRSC 280 G +PKG ++ + I +H + +VW + F P RF G + +H +A L FS G R+C Sbjct: 402 GRSLPKGIMVLLSIYGLHHNPKVW-PNPEVFDPFRFAPG---SAQHSHAFLPFSGGSRNC 457 Query: 279 IGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITLRPKFGLPMILKSL 124 IG+ FAM E K A+ L RF P + P+ + L+ K G+ + L+ L Sbjct: 458 IGKQFAMNELKVATALTLLRFELLPDPTRIPIPIARLVLKSKNGIHLRLRRL 509
>CP4A4_RABIT (P10611) Cytochrome P450 4A4 precursor (EC 1.14.14.1) (CYPIVA4)| (Prostaglandin omega-hydroxylase) (P450-P-2) Length = 510 Score = 69.3 bits (168), Expect = 5e-12 Identities = 38/112 (33%), Positives = 60/112 (53%) Frame = -3 Query: 459 GIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPNALLSFSSGPRSC 280 G +PKG ++ + I +H + +VW ++ F P RF + H +A L FS G R+C Sbjct: 402 GRSLPKGVILFLSIYGLHYNPKVW-QNPEVFDPFRF---APDSAYHSHAFLPFSGGARNC 457 Query: 279 IGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITLRPKFGLPMILKSL 124 IG+ FAM E K +A+ L RF P + P+ + L+ K G+ + L+ L Sbjct: 458 IGKQFAMRELKVAVALTLVRFELLPDPTRIPIPIARVVLKSKNGIHLRLRKL 509
>CP341_MOUSE (Q9JMA7) Cytochrome P450 3A41 (EC 1.14.14.1)| Length = 504 Score = 69.3 bits (168), Expect = 5e-12 Identities = 33/95 (34%), Positives = 51/95 (53%) Frame = -3 Query: 495 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPN 316 ++R D+E+ G+ +PKG+ + IP +H D + W E EF+P RF + P Sbjct: 374 LERFCKKDVELNGVYIPKGSTVMIPSYALHHDPQHWPEP-EEFQPERFSKE-NKGSIDPY 431 Query: 315 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSF 211 + F GPR+CIG FA + K + ++Q FSF Sbjct: 432 LYMPFGIGPRNCIGMRFAFMTMKLALTKVMQNFSF 466
>CP4F5_RAT (P51870) Cytochrome P450 4F5 (EC 1.14.14.1) (CYPIVF5)| Length = 526 Score = 69.3 bits (168), Expect = 5e-12 Identities = 43/112 (38%), Positives = 61/112 (54%) Frame = -3 Query: 459 GIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPNALLSFSSGPRSC 280 G +PKG + I I IH + VW D F P RF++ R + P + + FS+GPR+C Sbjct: 413 GRVIPKGNICVISIFGIHHNPSVW-PDPEVFDPFRFDSE-NRQKRSPLSFIPFSAGPRNC 470 Query: 279 IGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITLRPKFGLPMILKSL 124 IGQ FAM E K V+A+ L RF K ++I LR + GL + ++ L Sbjct: 471 IGQTFAMNEMKVVVALTLLRFRVLPDDKEPRRKPEII-LRAEGGLWLRMEPL 521
>C13B1_CAEEL (O17624) Putative cytochrome P450 cyp-13B1 (EC 1.14.-.-)| Length = 527 Score = 68.9 bits (167), Expect = 7e-12 Identities = 31/94 (32%), Positives = 54/94 (57%) Frame = -3 Query: 498 AIQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHP 319 A R+ +G I + KG I + ++HR KE+WGE+A++F P R+ + + +H Sbjct: 387 ACSRECVKPTTLGDIYIDKGVKIEADVMSLHRSKEIWGENADDFVPERW---LEPSSRHT 443 Query: 318 NALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRF 217 + + F +GPR C+G + EAK +A +L+R+ Sbjct: 444 MSWIPFGAGPRQCVGMRLGLSEAKTALAHLLRRY 477
>CYPE_BACSU (O08336) Probable bifunctional P-450:NADPH-P450 reductase 2| [Includes: Cytochrome P450 102 (EC 1.14.14.1); NADPH--cytochrome P450 reductase (EC 1.6.2.4)] Length = 1054 Score = 68.6 bits (166), Expect = 9e-12 Identities = 37/110 (33%), Positives = 59/110 (53%), Gaps = 1/110 (0%) Frame = -3 Query: 483 AGSDLEVGG-IKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPNALL 307 A D +GG + KG +T+ I +HRD+ WG DA +F+P RFE+ + +A Sbjct: 338 AKEDTVLGGEYPISKGQPVTVLIPKLHRDQNAWGPDAEDFRPERFED---PSSIPHHAYK 394 Query: 306 SFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITLRP 157 F +G R+CIG FA+ EA V+ ++L+ F Y + +T++P Sbjct: 395 PFGNGQRACIGMQFALQEATMVLGLVLKHFELINHTGYELKIKEALTIKP 444
>CP4AC_RAT (P24464) Cytochrome P450 4A12 (EC 1.14.14.1) (CYPIVA12) (CYPIVA8)| (P450-KP1) (P450-PP1) Length = 508 Score = 68.2 bits (165), Expect = 1e-11 Identities = 37/113 (32%), Positives = 58/113 (51%) Frame = -3 Query: 459 GIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPNALLSFSSGPRSC 280 G +PKG + + +H + VW + F P RF + +H ++ L FS G R+C Sbjct: 400 GRSLPKGITVMLSFYGLHHNPTVW-PNPEVFDPYRF---APESSRHSHSFLPFSGGARNC 455 Query: 279 IGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITLRPKFGLPMILKSLE 121 IG+ FAM E K +A+ L RF P + P+ + L+ K G+ + LK L+ Sbjct: 456 IGKQFAMNELKVAVALTLLRFELLPDPTRIPIPIPRLVLKSKNGIYLRLKKLQ 508
>CP4Z1_HUMAN (Q86W10) Cytochrome P450 4Z1 (EC 1.14.14.1) (CYPIVZ1)| Length = 505 Score = 67.8 bits (164), Expect = 2e-11 Identities = 41/114 (35%), Positives = 61/114 (53%), Gaps = 2/114 (1%) Frame = -3 Query: 459 GIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPNALLSFSSGPRSC 280 G +P G + I I +H + W ED F P+RF + HP A + FS+G R+C Sbjct: 395 GRSLPAGITVFINIWALHHNPYFW-EDPQVFNPLRFSRENSEK-IHPYAFIPFSAGLRNC 452 Query: 279 IGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDV--ITLRPKFGLPMILKSL 124 IGQ+FA+IE K +A+ L R F L+P + P V + L+ K G+ + K + Sbjct: 453 IGQHFAIIECKVAVALTLLR--FKLAPDHSRPPQPVRQVVLKSKNGIHVFAKKV 504
>CP52C_CANMA (P16496) Cytochrome P450 52A3 (EC 1.14.14.-) (CYPLIIA3)| (Alkane-inducible P450-ALK1-A) (P450-CM1) (CYP52A3-A) (Cytochrome P-450ALK) Length = 522 Score = 67.4 bits (163), Expect = 2e-11 Identities = 41/98 (41%), Positives = 53/98 (54%) Frame = -3 Query: 456 IKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPNALLSFSSGPRSCI 277 I VPKG+ + + HR K+ +GEDA EF+P R+ TR K A L F+ GPR C+ Sbjct: 414 IFVPKGSSVVYSVYKTHRLKQFYGEDAYEFRPERWFEPSTR--KLGWAYLPFNGGPRICL 471 Query: 276 GQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITL 163 GQ FA+ EA VIA + Q F S + P I L Sbjct: 472 GQQFALTEASYVIARLAQMFEHLESKDETYPPNKCIHL 509
>CP53_ASPNG (P17549) Benzoate 4-monooxygenase (EC 1.14.13.12)| (Benzoate-para-hydroxylase) (Cytochrome P450 53) (BpH) Length = 517 Score = 67.4 bits (163), Expect = 2e-11 Identities = 36/106 (33%), Positives = 58/106 (54%), Gaps = 2/106 (1%) Frame = -3 Query: 441 GTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPNALLSFSSGPRSCIGQNFA 262 G V+++P TIHR KE+WG DA +F P R++ + A + FS+GPR+C+G+N A Sbjct: 409 GDVVSVPSYTIHRSKEIWGPDAEQFVPERWD-PARLTPRQKAAFIPFSTGPRACVGRNVA 467 Query: 261 MIEAKAVIAMILQRFSFSLSPKYVHAPMDVIT--LRPKFGLPMILK 130 +E + + + F F + + PM+ LR GL + +K Sbjct: 468 EMELLVICGTVFRLFEFEMQQE---GPMETREGFLRKPLGLQVGMK 510
>CP4F8_HUMAN (P98187) Cytochrome P450 4F8 (EC 1.14.14.1) (CYPIVF8)| Length = 520 Score = 67.4 bits (163), Expect = 2e-11 Identities = 38/80 (47%), Positives = 47/80 (58%), Gaps = 2/80 (2%) Frame = -3 Query: 450 VPKGTVITIPIATIHRDKEVWGEDANEFKPMRF--ENGVTRAGKHPNALLSFSSGPRSCI 277 +PKG V I I IH + VW D + P RF EN R+ P A + FS+GPR+CI Sbjct: 414 IPKGNVCNINIFAIHHNPSVW-PDPEVYDPFRFDPENAQKRS---PMAFIPFSAGPRNCI 469 Query: 276 GQNFAMIEAKAVIAMILQRF 217 GQ FAM E K V+A+ L RF Sbjct: 470 GQKFAMAEMKVVLALTLLRF 489
>CP52B_CANTR (P30607) Cytochrome P450 52A2 (EC 1.14.14.-) (CYPLIIA2)| (Alkane-inducible P450-ALK2) Length = 522 Score = 67.0 bits (162), Expect = 3e-11 Identities = 39/106 (36%), Positives = 59/106 (55%), Gaps = 1/106 (0%) Frame = -3 Query: 495 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPN 316 + R G D + + V KG + + HR+K+++GEDA EF+P R+ T+ K Sbjct: 401 LPRGGGKD-GLSPVLVRKGQTVMYSVYAAHRNKQIYGEDALEFRPERWFEPETK--KLGW 457 Query: 315 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFS-FSLSPKYVHAP 181 A L F+ GPR C+GQ FA+ EA V +LQ FS ++ P ++P Sbjct: 458 AFLPFNGGPRICLGQQFALTEASYVTVRLLQEFSHLTMDPNTEYSP 503
>CP52A_CANTR (P10615) Cytochrome P450 52A1 (EC 1.14.14.-) (CYPLIIA1)| (Alkane-inducible P450-ALK1) Length = 543 Score = 67.0 bits (162), Expect = 3e-11 Identities = 36/90 (40%), Positives = 51/90 (56%) Frame = -3 Query: 486 KAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPNALL 307 + G + + I + KG V+ I HRDK+++GEDA F+P R+ TR K A + Sbjct: 421 RGGGEGGLSPIAIKKGQVVMYTILATHRDKDIYGEDAYVFRPERWFEPETR--KLGWAYV 478 Query: 306 SFSSGPRSCIGQNFAMIEAKAVIAMILQRF 217 F+ GPR C+GQ FA+ EA V +LQ F Sbjct: 479 PFNGGPRICLGQQFALTEASYVTVRLLQEF 508
>C6A14_DROME (Q9V4U7) Probable cytochrome P450 6a14 (EC 1.14.-.-) (CYPVIA14)| Length = 509 Score = 67.0 bits (162), Expect = 3e-11 Identities = 35/85 (41%), Positives = 50/85 (58%) Frame = -3 Query: 456 IKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPNALLSFSSGPRSCI 277 I + KG + IP+ IH D E++ E +F P RF+ + +HP A L F GPR+CI Sbjct: 398 IVLDKGILALIPVHNIHHDPEIYPEP-EKFDPSRFDPEEVK-NRHPMAYLPFGDGPRNCI 455 Query: 276 GQNFAMIEAKAVIAMILQRFSFSLS 202 G F I+AK + +L+RF FS+S Sbjct: 456 GLRFGKIQAKIGLVSLLRRFKFSVS 480
>CP4FC_HUMAN (Q9HCS2) Cytochrome P450 4F12 (EC 1.14.14.1) (CYPIVF12)| Length = 524 Score = 66.6 bits (161), Expect = 4e-11 Identities = 35/83 (42%), Positives = 49/83 (59%) Frame = -3 Query: 459 GIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPNALLSFSSGPRSC 280 G +PKG I I +H + VW D + P RF+ ++ G+ P A + FS+GPR+C Sbjct: 411 GRVIPKGITCLIDIIGVHHNPTVW-PDPEVYDPFRFDPENSK-GRSPLAFIPFSAGPRNC 468 Query: 279 IGQNFAMIEAKAVIAMILQRFSF 211 IGQ FAM E K V+A++L F F Sbjct: 469 IGQAFAMAEMKVVLALMLLHFRF 491
>CYPD_BACSU (O08394) Probable bifunctional P-450:NADPH-P450 reductase 1| [Includes: Cytochrome P450 102 (EC 1.14.14.1); NADPH--cytochrome P450 reductase (EC 1.6.2.4)] Length = 1061 Score = 66.6 bits (161), Expect = 4e-11 Identities = 38/107 (35%), Positives = 58/107 (54%), Gaps = 1/107 (0%) Frame = -3 Query: 474 DLEVGG-IKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPNALLSFS 298 D +GG + I++ I +HRD++ WG+DA EF+P RFE+ + +A F Sbjct: 341 DTVIGGKFPITTNDRISVLIPQLHRDRDAWGKDAEEFRPERFEH---QDQVPHHAYKPFG 397 Query: 297 SGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITLRP 157 +G R+CIG FA+ EA V+ MIL+ F+ Y +TL+P Sbjct: 398 NGQRACIGMQFALHEATLVLGMILKYFTLIDHENYELDIKQTLTLKP 444
>CP52K_CANMA (Q12589) Cytochrome P450 52A11 (EC 1.14.14.-) (CYPLIIA11)| (Alkane-inducible P450-ALK8) Length = 519 Score = 66.6 bits (161), Expect = 4e-11 Identities = 38/94 (40%), Positives = 55/94 (58%), Gaps = 2/94 (2%) Frame = -3 Query: 456 IKVPKGTVITIPIATIHRDKEVWGEDANEFKPMR-FENGVTRAGKHPNALLSFSSGPRSC 280 I V KG + + + RD++ +G+DANEF+P R FE V + G A L F+ GPR C Sbjct: 410 ILVRKGQTVMYSVYALQRDEKYYGKDANEFRPERWFEPEVRKLGW---AFLPFNGGPRIC 466 Query: 279 IGQNFAMIEAKAVIAMILQRF-SFSLSPKYVHAP 181 +GQ FA+ EA V+ ++Q F + LSP + P Sbjct: 467 LGQQFALTEASYVLVRLIQSFETLELSPDAPYPP 500
>THAS_PIG (P47787) Thromboxane-A synthase (EC 5.3.99.5) (TXA synthase) (TXS)| Length = 534 Score = 66.2 bits (160), Expect = 5e-11 Identities = 39/118 (33%), Positives = 59/118 (50%), Gaps = 3/118 (2%) Frame = -3 Query: 489 RKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPNAL 310 R+A D EV G ++P GTV+ + + +H D + W F P RF R + P Sbjct: 413 REAARDCEVLGQRIPAGTVLEVAVGALHHDPKHWPHPET-FDPERFTAEAQRL-QQPFTY 470 Query: 309 LSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDV---ITLRPKFGL 145 L F +GPRSC+G ++E K + IL++F F P+ P+ + L PK G+ Sbjct: 471 LPFGAGPRSCLGVQLGLLEIKLTLLHILRKFRFEACPE-TQVPLQLESKSALSPKNGV 527
>C6A13_DROME (Q9V4U9) Probable cytochrome P450 6a13 (EC 1.14.-.-) (CYPVIA13)| Length = 493 Score = 65.5 bits (158), Expect = 8e-11 Identities = 34/82 (41%), Positives = 49/82 (59%) Frame = -3 Query: 441 GTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPNALLSFSSGPRSCIGQNFA 262 G+ I IP+ +IH D E++ D +F P RFE +A +HP A L F GPR+CIG+ F Sbjct: 384 GSKIIIPVHSIHHDPELY-PDPEKFDPSRFEPEEIKA-RHPFAYLPFGEGPRNCIGERFG 441 Query: 261 MIEAKAVIAMILQRFSFSLSPK 196 ++ K + +L+ F FS S K Sbjct: 442 KLQVKVGLVYLLRDFKFSRSEK 463
>THAS_HUMAN (P24557) Thromboxane-A synthase (EC 5.3.99.5) (TXA synthase) (TXS)| Length = 533 Score = 65.5 bits (158), Expect = 8e-11 Identities = 33/98 (33%), Positives = 48/98 (48%) Frame = -3 Query: 489 RKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPNAL 310 R+A D EV G ++P G V+ + + +H D E W F P RF R P Sbjct: 412 REAAQDCEVLGQRIPAGAVLEMAVGALHHDPEHW-PSPETFNPERF-TAEARQQHRPFTY 469 Query: 309 LSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPK 196 L F +GPRSC+G ++E K + +L +F F P+ Sbjct: 470 LPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQACPE 507
>CP4C1_BLADI (P29981) Cytochrome P450 4C1 (EC 1.14.14.1) (CYPIVC1)| Length = 511 Score = 65.5 bits (158), Expect = 8e-11 Identities = 41/126 (32%), Positives = 68/126 (53%), Gaps = 5/126 (3%) Frame = -3 Query: 495 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGE----DANEFKPMRFENGVTRAG 328 I R D ++G VP G ++ + I +HR+++ + + + F P R A Sbjct: 383 IGRVLKEDTKIGDYLVPAGCMMNLQIYHVHRNQDQYPNPEAFNPDNFLPERV------AK 436 Query: 327 KHPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSF-SLSPKYVHAPMDVITLRPKF 151 +HP A + FS+GPR+CIGQ FA +E K V++ IL+ F S+ + M+ + LRP+ Sbjct: 437 RHPYAYVPFSAGPRNCIGQKFATLEEKTVLSSILRNFKVRSIEKREDLTLMNELILRPES 496 Query: 150 GLPMIL 133 G+ + L Sbjct: 497 GIKVEL 502
>CP52F_CANTR (P30608) Cytochrome P450 52A6 (EC 1.14.14.-) (CYPLIIA6)| (Alkane-inducible P450-ALK3) Length = 524 Score = 65.1 bits (157), Expect = 1e-10 Identities = 36/93 (38%), Positives = 53/93 (56%), Gaps = 1/93 (1%) Frame = -3 Query: 456 IKVPKGTVITIPIATIHRDKEVWGEDANEFKPMR-FENGVTRAGKHPNALLSFSSGPRSC 280 I +PKG+ + + HR +E +G+DA++F+P R FE + G A + F+ GPR C Sbjct: 416 IFIPKGSTVAYIVYKTHRLEEYYGKDADDFRPERWFEPSTKKLGW---AYVPFNGGPRIC 472 Query: 279 IGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAP 181 +GQ FA+ EA VI ++Q F SP V P Sbjct: 473 LGQQFALTEASYVITRLVQMFETVSSPPDVEYP 505
>CP4P3_DROME (Q9V559) Probable cytochrome P450 4p3 (EC 1.14.-.-) (CYPIVP3)| Length = 515 Score = 65.1 bits (157), Expect = 1e-10 Identities = 40/108 (37%), Positives = 62/108 (57%), Gaps = 5/108 (4%) Frame = -3 Query: 498 AIQRKAGSDLEVG-GIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRF--ENGVTRAG 328 A+ R+ + E+ G+ +PKG+ I + + IHR+ E W + EF+P RF EN R Sbjct: 390 AMGRETTRETELSNGLILPKGSQIFVHVFDIHRNPEYW-DSPEEFRPERFLPENSQNR-- 446 Query: 327 KHPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSF--SLSPKYV 190 H A + FS+G R+CIGQ FAM E K ++ +L++F + PK + Sbjct: 447 -HTYAYIPFSAGQRNCIGQKFAMQEMKTLMVALLKQFQILPEIDPKTI 493
>CP2DI_RAT (Q64680) Cytochrome P450 2D18 (EC 1.14.14.1) (CYPIID18) (P450| 2D-29/2D-35) Length = 500 Score = 65.1 bits (157), Expect = 1e-10 Identities = 35/97 (36%), Positives = 54/97 (55%) Frame = -3 Query: 495 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPN 316 + K D+EV G +PKGT + I ++++ +D+ VW E F P F + KH Sbjct: 377 VPHKTSRDIEVQGFLIPKGTTLIINLSSVLKDETVW-EKPLRFHPEHFLDAQGNFVKH-E 434 Query: 315 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSL 205 A + FS+G R+C+G+ A +E +LQRFSFS+ Sbjct: 435 AFMPFSAGRRACLGEPLARMELFLFFTCLLQRFSFSV 471
>CP343_HUMAN (Q9HB55) Cytochrome P450 3A43 (EC 1.14.14.1)| Length = 503 Score = 64.7 bits (156), Expect = 1e-10 Identities = 33/100 (33%), Positives = 52/100 (52%), Gaps = 5/100 (5%) Frame = -3 Query: 495 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPN 316 + R D+E+ G+ +PKG + +PI +H D + W E +F P RF K+ + Sbjct: 373 VTRVCKKDIEINGVFIPKGLAVMVPIYALHHDPKYWTE-PEKFCPERFSK------KNKD 425 Query: 315 AL-----LSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSF 211 ++ + F +GPR+CIG FA+ K + LQ FSF Sbjct: 426 SIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQNFSF 465
>THAS_RAT (P49430) Thromboxane-A synthase (EC 5.3.99.5) (TXA synthase) (TXS)| Length = 533 Score = 64.3 bits (155), Expect = 2e-10 Identities = 33/98 (33%), Positives = 49/98 (50%) Frame = -3 Query: 489 RKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPNAL 310 R+A D EV G +P G+V+ I + +H D E W + F P RF R + P Sbjct: 412 REAAQDCEVLGQHIPAGSVLEIAVGALHHDPEHW-PNPETFDPERF-TAEARLQQKPFTY 469 Query: 309 LSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPK 196 L F +GPRSC+G ++ K + +L +F F P+ Sbjct: 470 LPFGAGPRSCLGVRLGLLVVKLTLLQVLHKFRFEACPE 507
>CP52D_CANMA (P16141) Cytochrome P450 52A4 (EC 1.14.14.-) (CYPLIIA4)| (Alkane-inducible P450-ALK3-A) (P450-CM2) Length = 537 Score = 64.3 bits (155), Expect = 2e-10 Identities = 37/93 (39%), Positives = 51/93 (54%) Frame = -3 Query: 495 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPN 316 + R G D + I + KG + I+ HRD ++GEDAN F+P R+ TR K Sbjct: 416 LPRGGGKD-GMSPIAIKKGQNVMYTISATHRDPSIYGEDANVFRPERWFEPETR--KLGW 472 Query: 315 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRF 217 A + F+ GPR C+GQ FA+ EA V +LQ F Sbjct: 473 AYVPFNGGPRICLGQQFALTEASYVTVRLLQEF 505
>CP133_DROME (Q9VGB3) Probable cytochrome P450 313a3 (EC 1.14.-.-)| (CYPCCCXIIIA3) Length = 492 Score = 63.9 bits (154), Expect = 2e-10 Identities = 32/89 (35%), Positives = 49/89 (55%) Frame = -3 Query: 459 GIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPNALLSFSSGPRSC 280 G+ +PKG I I I HR+++ WG D + F P F R +HP A + FS G R+C Sbjct: 380 GVVIPKGVGIGIDIFATHRNRDHWGTDPSSFNPDHFLPDNVR-DRHPYAYIPFSKGRRNC 438 Query: 279 IGQNFAMIEAKAVIAMILQRFSFSLSPKY 193 IG + ++ +K ++ IL+ S S +Y Sbjct: 439 IGWKYGLMSSKLALSKILRNCKVSTSFRY 467
>CP1A1_RAT (P00185) Cytochrome P450 1A1 (EC 1.14.14.1) (CYP1A1) (CYPIA1)| (P450-C) (P450MT2) [Contains: Cytochrome P450MT2A; Cytochrome P450MT2B] Length = 524 Score = 63.9 bits (154), Expect = 2e-10 Identities = 37/130 (28%), Positives = 65/130 (50%), Gaps = 1/130 (0%) Frame = -3 Query: 474 DLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKH-PNALLSFS 298 D + G +PKG + + ++ D+E+WG D NEF+P RF KH ++ F Sbjct: 397 DTSLNGFYIPKGHCVFVNQWQVNHDQELWG-DPNEFRPERFLTSSGTLDKHLSEKVILFG 455 Query: 297 SGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITLRPKFGLPMILKSLEM 118 G R CIG+ +E +A++LQ+ F++SP + + + P +GL +L+ Sbjct: 456 LGKRKCIGETIGRLEVFLFLAILLQQMEFNVSPG------EKVDMTPAYGL-----TLKH 504 Query: 117 *RCVEYNTRL 88 RC + ++ Sbjct: 505 ARCEHFQVQM 514
>CP4F6_RAT (P51871) Cytochrome P450 4F6 (EC 1.14.14.1) (CYPIVF6)| Length = 537 Score = 63.9 bits (154), Expect = 2e-10 Identities = 36/83 (43%), Positives = 47/83 (56%), Gaps = 2/83 (2%) Frame = -3 Query: 459 GIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRF--ENGVTRAGKHPNALLSFSSGPR 286 G +PKG + I I +H + VW D + P RF EN R+ P A + FS+GPR Sbjct: 411 GRVIPKGNICVISIFGVHHNPSVW-PDPEVYNPFRFDPENPQKRS---PLAFIPFSAGPR 466 Query: 285 SCIGQNFAMIEAKAVIAMILQRF 217 +CIGQ FAM E K +A+ L RF Sbjct: 467 NCIGQTFAMSEIKVALALTLLRF 489
>CP4P2_DROME (Q9V557) Probable cytochrome P450 4p2 (EC 1.14.-.-) (CYPIVP2)| Length = 520 Score = 63.5 bits (153), Expect = 3e-10 Identities = 42/106 (39%), Positives = 62/106 (58%), Gaps = 4/106 (3%) Frame = -3 Query: 459 GIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRF--ENGVTRAGKHPNALLSFSSGPR 286 G+ +PK + I I + IHR+ + W E EF+P RF +N + R HP A + FS+G R Sbjct: 407 GLILPKRSQINIHVFDIHRNPKYW-ESPEEFRPERFLPQNCLKR---HPYAYIPFSAGQR 462 Query: 285 SCIGQNFAMIEAKAVIAMILQRFSF--SLSPKYVHAPMDVITLRPK 154 +CIGQ +AM E K ++ +IL+ F + PK + + ITLR K Sbjct: 463 NCIGQKYAMQEMKTLMVVILKHFKILPVIDPKSIVFQVG-ITLRFK 507
>CP135_DROME (Q9VGB5) Probable cytochrome P450 313a5 (EC 1.14.-.-)| (CYPCCCXIIIA5) Length = 487 Score = 63.2 bits (152), Expect = 4e-10 Identities = 32/89 (35%), Positives = 49/89 (55%) Frame = -3 Query: 459 GIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPNALLSFSSGPRSC 280 G +P+G + I I HR+K++WG AN F P F RA + P + L FS G ++C Sbjct: 375 GFYIPEGVTLMIDIFHTHRNKDIWGPQANAFNPDNFLPENKRA-RPPYSYLPFSKGKKTC 433 Query: 279 IGQNFAMIEAKAVIAMILQRFSFSLSPKY 193 +G ++I AK +A IL+ + S + Y Sbjct: 434 LGWKLSLISAKLALAKILRNYMLSTTFLY 462
>CP4F1_RAT (P33274) Cytochrome P450 4F1 (EC 1.14.14.1) (CYPIVF1) (P450-A3)| Length = 524 Score = 63.2 bits (152), Expect = 4e-10 Identities = 40/105 (38%), Positives = 54/105 (51%) Frame = -3 Query: 459 GIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPNALLSFSSGPRSC 280 G +PKG + I I IH + VW D + P RF+ + P A + FS+GPR+C Sbjct: 411 GRTIPKGIICLISIFGIHHNPSVW-PDPEVYNPFRFDPENIKDSS-PLAFIPFSAGPRNC 468 Query: 279 IGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITLRPKFGL 145 IGQ FAM E K +A+ L RF K ++I LR + GL Sbjct: 469 IGQTFAMSEMKVALALTLLRFRLLPDDKEPRRQPELI-LRAEGGL 512
>CP2D4_RAT (P13108) Cytochrome P450 2D4 (EC 1.14.14.1) (CYPIID4) (P450-DB4)| (P450-CMF3) (Debrisoquine 4-hydroxylase) Length = 500 Score = 63.2 bits (152), Expect = 4e-10 Identities = 34/97 (35%), Positives = 53/97 (54%) Frame = -3 Query: 495 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPN 316 + K D+EV G +PKGT + ++++ +D+ VW E F P F + KH Sbjct: 377 VPHKTSRDIEVQGFLIPKGTTLITNLSSVLKDETVW-EKPLRFHPEHFLDAQGNFVKH-E 434 Query: 315 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSL 205 A + FS+G R+C+G+ A +E +LQRFSFS+ Sbjct: 435 AFMPFSAGRRACLGEPLARMELFLFFTCLLQRFSFSV 471
>CP52H_CANTR (P30610) Cytochrome P450 52A8 (EC 1.14.14.-) (CYPLIIA8)| (Alkane-inducible P450-ALK5) Length = 517 Score = 63.2 bits (152), Expect = 4e-10 Identities = 41/112 (36%), Positives = 58/112 (51%), Gaps = 1/112 (0%) Frame = -3 Query: 495 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPN 316 + R GSD + V KG ++ I + H D +G+DA EF+P R+ TR K Sbjct: 396 LPRGGGSDGN-SPVLVKKGEAVSYGINSTHLDPVYYGDDAAEFRPERWNEPSTR--KLGW 452 Query: 315 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRF-SFSLSPKYVHAPMDVITL 163 A L F+ GPR C+GQ FA+ EA V+ + Q F + L P V+ P + L Sbjct: 453 AYLPFNGGPRICLGQQFALTEAGYVLVRLAQSFDTLELKPPVVYPPKRLTNL 504
>CP52L_DEBHA (Q9Y757) Cytochrome P450 52A12 (EC 1.14.14.-) (Alkane hydroxylase| 1) (Alkane-inducible p450alk 1) (DH-ALK2) Length = 519 Score = 63.2 bits (152), Expect = 4e-10 Identities = 33/80 (41%), Positives = 48/80 (60%) Frame = -3 Query: 456 IKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPNALLSFSSGPRSCI 277 I + KG +T + +HRD++ +G+D+ F+P R+ TR K A L F+ GPR C+ Sbjct: 411 IFIAKGQTVTYTVYAMHRDEQFYGKDSEVFRPERWFEPETR--KLGWAFLPFNGGPRICL 468 Query: 276 GQNFAMIEAKAVIAMILQRF 217 GQ FA+ EA VIA + Q F Sbjct: 469 GQQFALTEASYVIARLAQLF 488
>CP2L1_PANAR (Q27712) Cytochrome P450 2L1 (EC 1.14.14.1) (CYPIIL1)| Length = 492 Score = 62.8 bits (151), Expect = 5e-10 Identities = 36/100 (36%), Positives = 55/100 (55%) Frame = -3 Query: 495 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPN 316 + D E+ G ++PKGTV+ + HRD W E NEF P F + + K + Sbjct: 367 VSHYTNQDTELAGYRLPKGTVVMSHLECCHRDPSYW-EKPNEFYPEHFLDDQGKFVKREH 425 Query: 315 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPK 196 L++FS G R C+G++ A +E ++ ILQ F+FS +PK Sbjct: 426 -LVNFSVGRRVCVGESLARMELFVFLSAILQNFTFS-APK 463
>CP52E_CANMA (P24458) Cytochrome P450 52A5 (EC 1.14.14.-) (CYPLIIA5)| (Alkane-inducible P450-ALK2-A) (CYP52A3-B) Length = 523 Score = 62.8 bits (151), Expect = 5e-10 Identities = 38/98 (38%), Positives = 52/98 (53%) Frame = -3 Query: 456 IKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPNALLSFSSGPRSCI 277 I VPKG+ + + HR +E +G+DA EF+P R+ TR K A + F+ GPR C+ Sbjct: 415 IFVPKGSSVVYTVYKTHRLEEYYGKDAYEFRPERWFEPSTR--KLGWAYVPFNGGPRICL 472 Query: 276 GQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITL 163 GQ FA+ EA VI + Q F S + P I L Sbjct: 473 GQQFALTEASYVITRLAQMFEHLESKDETYPPNKCIHL 510
>C4AA1_DROME (Q9V7G5) Probable cytochrome P450 4aa1 (EC 1.14.-.-) (CYPIVAA1)| Length = 514 Score = 62.8 bits (151), Expect = 5e-10 Identities = 44/125 (35%), Positives = 66/125 (52%), Gaps = 3/125 (2%) Frame = -3 Query: 495 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRF--ENGVTRAGKH 322 I RK G ++ + +P G+ + I HR ++ D +F+P RF EN R H Sbjct: 385 IARKLGEEVRLAKHTLPAGSNVFICPYATHRLAHIY-PDPEKFQPERFSPENSENR---H 440 Query: 321 PNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFS-FSLSPKYVHAPMDVITLRPKFGL 145 P A L FS+GPR CIG FA++E K +++ +L+ + ++ K A ITLR GL Sbjct: 441 PYAFLPFSAGPRYCIGNRFAIMEIKTIVSRLLRSYQLLPVTGKTTIAATFRITLRASGGL 500 Query: 144 PMILK 130 + LK Sbjct: 501 WVRLK 505
>CP4FE_MOUSE (Q9EP75) Cytochrome P450 4F14 (EC 1.14.13.30) (Leukotriene-B4| omega-hydroxylase) (Leukotriene-B4 20-monooxygenase) (Cytochrome P450-LTB-omega) (Cyp4f-14) Length = 524 Score = 62.8 bits (151), Expect = 5e-10 Identities = 40/105 (38%), Positives = 54/105 (51%) Frame = -3 Query: 459 GIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPNALLSFSSGPRSC 280 G +PKG + I I IH + VW D + P RF+ + P A + FS+GPR+C Sbjct: 411 GRTIPKGIICLISIFGIHHNPSVW-PDPEVYDPFRFDPENIKDSS-PLAFIPFSAGPRNC 468 Query: 279 IGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITLRPKFGL 145 IGQ FAM E K +A+ L RF K ++I LR + GL Sbjct: 469 IGQTFAMSEMKVALALTLLRFRLLPDDKEPRRQPELI-LRAEGGL 512
>CP52M_DEBHA (Q9Y758) Cytochrome P450 52A13 (EC 1.14.14.-) (Alkane hydroxylase| 2) (Alkane-inducible p450alk 2) (DH-ALK2) Length = 519 Score = 62.8 bits (151), Expect = 5e-10 Identities = 32/80 (40%), Positives = 48/80 (60%) Frame = -3 Query: 456 IKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPNALLSFSSGPRSCI 277 I V KGT + + + HR +E +G+DA+EFKP R+ + K A + F+ GPR C+ Sbjct: 412 IYVGKGTTVAYSVYSTHRMEEYYGKDADEFKPERW----AESRKLGWAYVPFNGGPRICL 467 Query: 276 GQNFAMIEAKAVIAMILQRF 217 GQ FA+ EA ++ +LQ F Sbjct: 468 GQQFALTEASYIVTRLLQMF 487
>C28C1_DROME (Q9VYT8) Probable cytochrome P450 28c1 (EC 1.14.-.-) (CYPXXVIIIC1)| Length = 505 Score = 62.4 bits (150), Expect = 7e-10 Identities = 30/87 (34%), Positives = 49/87 (56%) Frame = -3 Query: 456 IKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPNALLSFSSGPRSCI 277 +K+ G + +PI +H D +++ E + F+P RF +G + K L F +GPR C+ Sbjct: 387 LKLRPGDHVMVPIYALHNDPDLYPEP-DVFRPERFLDGGLKNCKQQGIFLGFGNGPRQCV 445 Query: 276 GQNFAMIEAKAVIAMILQRFSFSLSPK 196 G + AKA +A I+QRF +SP+ Sbjct: 446 GMRLGLAMAKAALAAIVQRFEVVVSPR 472
>CP2D1_RAT (P10633) Cytochrome P450 2D1 (EC 1.14.14.1) (CYPIID1) (P450-DB1)| (P450-CMF1A) (P450-UT-7) (Debrisoquine 4-hydroxylase) Length = 504 Score = 62.4 bits (150), Expect = 7e-10 Identities = 34/97 (35%), Positives = 54/97 (55%) Frame = -3 Query: 495 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPN 316 + R D+EV +PKGT + I ++++ +D+ VW E + F P F + KH Sbjct: 377 LPRFTSCDIEVQDFVIPKGTTLIINLSSVLKDETVW-EKPHRFHPEHFLDAQGNFVKH-E 434 Query: 315 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSL 205 A + FS+G R+C+G+ A +E +LQRFSFS+ Sbjct: 435 AFMPFSAGRRACLGEPLARMELFLFFTCLLQRFSFSV 471
>CP4E3_DROME (Q9VL92) Cytochrome P450 4e3 (EC 1.14.-.-) (CYPIVE3)| Length = 526 Score = 62.4 bits (150), Expect = 7e-10 Identities = 33/93 (35%), Positives = 53/93 (56%) Frame = -3 Query: 495 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPN 316 I R D ++ G VPKGT + + + + + ++ +D + F+P RFE P Sbjct: 377 IGRYCDKDYDINGSIVPKGTTLNLALILLGYNDRIF-KDPHHFRPERFEEEKPA----PF 431 Query: 315 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRF 217 L FS+GPR+CIGQ FA++E K VI+ +++ F Sbjct: 432 EYLPFSAGPRNCIGQKFALLELKTVISKVVRSF 464
>CP17A_MOUSE (P27786) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 507 Score = 62.4 bits (150), Expect = 7e-10 Identities = 37/102 (36%), Positives = 52/102 (50%), Gaps = 4/102 (3%) Frame = -3 Query: 495 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKH-- 322 I KA D +G +PK T + I + +H DK W + + F P RF + G H Sbjct: 370 IPHKANIDSSIGEFAIPKDTHVIINLWALHHDKNEW-DQPDRFMPERF---LDPTGSHLI 425 Query: 321 --PNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLS 202 + L F +GPRSCIG+ A E +A++LQRF F +S Sbjct: 426 TPTPSYLPFGAGPRSCIGEALARQELFIFMALLLQRFDFDVS 467
>CP2D6_PANTR (Q2XNC8) Cytochrome P450 2D6 (EC 1.14.14.1) (CYPIID6)| Length = 497 Score = 62.0 bits (149), Expect = 9e-10 Identities = 34/90 (37%), Positives = 51/90 (56%) Frame = -3 Query: 474 DLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPNALLSFSS 295 D+EV G ++PKGT + ++++ +DK VW E F P F + K P A L FS+ Sbjct: 381 DIEVQGFRIPKGTTLFTNLSSVLKDKAVW-EKPFRFHPEHFLDAQGHFVK-PEAFLPFSA 438 Query: 294 GPRSCIGQNFAMIEAKAVIAMILQRFSFSL 205 G R+C+G+ A +E +LQ FSFS+ Sbjct: 439 GRRACLGEPLARMELFLFFTSLLQHFSFSV 468
>C71AI_ARATH (Q9SAB6) Cytochrome P450 71A18 (EC 1.14.-.-)| Length = 497 Score = 62.0 bits (149), Expect = 9e-10 Identities = 34/99 (34%), Positives = 49/99 (49%) Frame = -3 Query: 495 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPN 316 + R D++V G + GT + I +IHRD +WG DA EFKP R + Sbjct: 368 LPRLLTEDVKVKGYDIAAGTEVLINAWSIHRDPAIWGPDAEEFKPERHLDSTLDYHGQDL 427 Query: 315 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSP 199 + F SG R C G N AM + +A ++ RF +S+ P Sbjct: 428 KYIPFGSGRRICPGINLAMGLVEVTLANLVGRFDWSVDP 466
>C4D21_DROME (Q9VLZ7) Probable cytochrome P450 4d21 (EC 1.14.-.-) (CYPIVD21)| Length = 511 Score = 62.0 bits (149), Expect = 9e-10 Identities = 32/86 (37%), Positives = 53/86 (61%) Frame = -3 Query: 474 DLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPNALLSFSS 295 DL++G I +P T I + ++RD E + D FKP R+ + T + P A + FSS Sbjct: 393 DLKIGEITIPGNTSILLMPYYVYRDPEYF-PDPLVFKPERWMDMKTTSNTPPLAYIPFSS 451 Query: 294 GPRSCIGQNFAMIEAKAVIAMILQRF 217 GP++CIGQ FA ++ KA+I+ +++ + Sbjct: 452 GPKNCIGQKFANLQMKALISKVIRHY 477
>CP4P1_DROME (Q9V558) Cytochrome P450 4p1 (EC 1.14.-.-) (CYPIVP1)| Length = 513 Score = 62.0 bits (149), Expect = 9e-10 Identities = 37/94 (39%), Positives = 58/94 (61%), Gaps = 3/94 (3%) Frame = -3 Query: 489 RKAGSDLEVG-GIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRF--ENGVTRAGKHP 319 R+A + E+ G+ +PKG ITI + IHR+ + W + EF+P RF EN R H Sbjct: 391 REAVQETELANGLILPKGAQITIHVFDIHRNAKYW-DSPEEFRPERFLPENVQDR---HT 446 Query: 318 NALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRF 217 A + FS+G R+CIG+ +AM E K ++ ++L++F Sbjct: 447 YAYVPFSAGQRNCIGKKYAMQEMKTLMVVLLKQF 480
>CP4F4_RAT (P51869) Cytochrome P450 4F4 (EC 1.14.14.1) (CYPIVF4)| Length = 522 Score = 62.0 bits (149), Expect = 9e-10 Identities = 36/94 (38%), Positives = 51/94 (54%), Gaps = 1/94 (1%) Frame = -3 Query: 495 IQRKAGSDLEV-GGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHP 319 I R+ D+ + G +PKG + I I H + VW D + P RF+ + + P Sbjct: 398 ISRRCTQDIVLPDGRVIPKGVICIINIFATHHNPTVW-PDPEVYDPFRFDPENIK-DRSP 455 Query: 318 NALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRF 217 A + FS+GPR+CIGQ FAM E K +A+ L RF Sbjct: 456 LAFIPFSAGPRNCIGQTFAMNEMKVALALTLLRF 489
>CP4E2_DROME (Q27606) Cytochrome P450 4e2 (EC 1.14.-.-) (CYPIVE2)| Length = 526 Score = 62.0 bits (149), Expect = 9e-10 Identities = 34/93 (36%), Positives = 58/93 (62%) Frame = -3 Query: 495 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPN 316 I R D + G VPKGT + + + + +++V+ +D ++F+P RFE + + G P Sbjct: 378 IGRFTEKDYVIDGDLVPKGTTLNLGLVMLGYNEKVF-KDPHKFRPERFE--LEKPG--PF 432 Query: 315 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRF 217 + FS+GPR+CIGQ FA++E K V++ I++ F Sbjct: 433 EYVPFSAGPRNCIGQKFALLEIKTVVSKIIRNF 465
>CP9F2_DROME (Q9VG82) Probable cytochrome P450 9f2 (EC 1.14.-.-) (CYPIXF2)| Length = 516 Score = 62.0 bits (149), Expect = 9e-10 Identities = 44/125 (35%), Positives = 68/125 (54%), Gaps = 8/125 (6%) Frame = -3 Query: 498 AIQRKAGSDL--EVGG--IKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRA 331 A+ R+ D+ +V G ++V KG VI +P HRD + + E+ +F P RF + + Sbjct: 386 AVDRECNKDITFDVDGQKVEVKKGDVIWLPTCGFHRDPKYF-ENPMKFDPERFSDE-NKE 443 Query: 330 GKHPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVIT----L 163 P F G R+CIG FA++EAKAVI +L+ + F+ + K P+++IT L Sbjct: 444 SIQPFTYFPFGLGQRNCIGSRFALLEAKAVIYYLLKDYRFAPAKKSC-IPLELITSGFQL 502 Query: 162 RPKFG 148 PK G Sbjct: 503 SPKGG 507
>C4AC3_DROME (Q9VMS7) Probable cytochrome P450 4ac3 (EC 1.14.-.-) (CYPIVAC3)| Length = 509 Score = 62.0 bits (149), Expect = 9e-10 Identities = 35/85 (41%), Positives = 52/85 (61%), Gaps = 2/85 (2%) Frame = -3 Query: 465 VGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRF--ENGVTRAGKHPNALLSFSSG 292 + G+ +PK I+I I I RD + + N+F P RF EN V R HP A + FS+G Sbjct: 395 MNGLVLPKNAQISIHIYDIMRDARHFPKP-NQFLPERFLPENSVNR---HPFAFVPFSAG 450 Query: 291 PRSCIGQNFAMIEAKAVIAMILQRF 217 PR+CIGQ F ++E K ++A +++ F Sbjct: 451 PRNCIGQKFGVLEIKVLLAAVIRNF 475
>CP2DR_MESAU (Q9QYG6) Cytochrome P450 2D27 (EC 1.14.14.-) (CYPIID27)| Length = 500 Score = 62.0 bits (149), Expect = 9e-10 Identities = 35/97 (36%), Positives = 53/97 (54%) Frame = -3 Query: 495 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPN 316 I D+EV G +PKGT + ++++ +D+ VW E F P F + R KH Sbjct: 377 IPHMTSHDVEVQGFLIPKGTTLIPNLSSVLKDETVW-EKPLHFHPEHFLDAQGRFVKH-E 434 Query: 315 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSL 205 A + FS+G R+C+G+ A +E +LQRFSFS+ Sbjct: 435 AFMPFSAGRRACLGEPLARMELFLFFTCLLQRFSFSV 471
>CP2D3_RAT (P12938) Cytochrome P450 2D3 (EC 1.14.14.1) (CYPIID3) (P450-DB3)| (Debrisoquine 4-hydroxylase) Length = 500 Score = 62.0 bits (149), Expect = 9e-10 Identities = 34/97 (35%), Positives = 53/97 (54%) Frame = -3 Query: 495 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPN 316 + K D+EV G +PKGT + ++++ +D+ VW E F P F + KH Sbjct: 377 LPHKTSRDIEVQGFLIPKGTTLIPNLSSVLKDETVW-EKPLRFHPEHFLDAQGNFVKH-E 434 Query: 315 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSL 205 A + FS+G R+C+G+ A +E +LQRFSFS+ Sbjct: 435 AFMPFSAGRRACLGEPLARMELFLFFTCLLQRFSFSV 471
>CP4F2_HUMAN (P78329) Cytochrome P450 4F2 (EC 1.14.13.30) (CYPIVF2)| (Leukotriene-B(4) omega-hydroxylase) (Leukotriene-B(4) 20-monooxygenase) (Cytochrome P450-LTB-omega) Length = 520 Score = 62.0 bits (149), Expect = 9e-10 Identities = 33/81 (40%), Positives = 46/81 (56%) Frame = -3 Query: 459 GIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPNALLSFSSGPRSC 280 G +PKG + I + H + VW D + P RF+ + + P A + FS+GPR+C Sbjct: 411 GRVIPKGIICLISVFGTHHNPAVW-PDPEVYDPFRFDPENIKE-RSPLAFIPFSAGPRNC 468 Query: 279 IGQNFAMIEAKAVIAMILQRF 217 IGQ FAM E K V+A+ L RF Sbjct: 469 IGQTFAMAEMKVVLALTLLRF 489
>CP4FB_HUMAN (Q9HBI6) Cytochrome P450 4F11 (EC 1.14.14.1) (CYPIVF11)| Length = 524 Score = 61.6 bits (148), Expect = 1e-09 Identities = 36/81 (44%), Positives = 45/81 (55%) Frame = -3 Query: 459 GIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPNALLSFSSGPRSC 280 G +PKG V I I IH + VW D + P RF N + P A + FS+GPR+C Sbjct: 411 GRVIPKGIVCLINIIGIHYNPTVW-PDPEVYDPFRF-NQENIKERSPLAFIPFSAGPRNC 468 Query: 279 IGQNFAMIEAKAVIAMILQRF 217 IGQ FAM E K V+A+ L F Sbjct: 469 IGQAFAMAEMKVVLALTLLHF 489
>CP132_DROME (Q9VGB4) Probable cytochrome P450 313a2 (EC 1.14.-.-)| (CYPCCCXIIIA2) Length = 493 Score = 61.2 bits (147), Expect = 1e-09 Identities = 32/100 (32%), Positives = 51/100 (51%), Gaps = 1/100 (1%) Frame = -3 Query: 489 RKAGSDLEVG-GIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPNA 313 R+ DL + G+ +PKG I+I I R+ + WG +A +F P F +HP A Sbjct: 369 RETLEDLRLSNGVVIPKGMTISIDIFNTQRNTDYWGSEAAQFNPENFLPEKIH-DRHPYA 427 Query: 312 LLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKY 193 + FS G R+CIG + ++ +K + IL+ + S Y Sbjct: 428 FIPFSKGKRNCIGWRYGLMSSKLALVKILRNYKLKTSFPY 467
>C86A1_ARATH (P48422) Cytochrome P450 86A1 (EC 1.14.-.-) (CYPLXXXVI)| (P450-dependent fatty acid omega-hydroxylase) Length = 513 Score = 61.2 bits (147), Expect = 1e-09 Identities = 37/118 (31%), Positives = 63/118 (53%), Gaps = 3/118 (2%) Frame = -3 Query: 474 DLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPN---ALLS 304 D+ G VP+G+ +T I +I R K +WGED EF+P R+ + P ++ Sbjct: 389 DVLPDGTFVPRGSTVTYSIYSIGRMKTIWGEDCLEFRPERWLTADGERFETPKDGYKFVA 448 Query: 303 FSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITLRPKFGLPMILK 130 F++GPR+C+G++ A + K+V + +L R+ P + +TL K GL + L+ Sbjct: 449 FNAGPRTCLGKDLAYNQMKSVASAVLLRYRVFPVPGHRVEQKMSLTLFMKNGLRVYLQ 506
>C97B3_ARATH (O23365) Cytochrome P450 97B3 (EC 1.14.-.-)| Length = 580 Score = 61.2 bits (147), Expect = 1e-09 Identities = 38/109 (34%), Positives = 54/109 (49%), Gaps = 21/109 (19%) Frame = -3 Query: 468 EVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRF-----ENGV----------TR 334 E G KVPKGT I I + +HR W ++ ++F+P RF NG+ + Sbjct: 443 EKEGHKVPKGTDIFISVYNLHRSPYFW-DNPHDFEPERFLRTKESNGIEGWAGFDPSRSP 501 Query: 333 AGKHPN------ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSL 205 +PN A L F GPR CIG FA++E+ +AM+ Q+F L Sbjct: 502 GALYPNEIIADFAFLPFGGGPRKCIGDQFALMESTVALAMLFQKFDVEL 550
>CP2D6_HUMAN (P10635) Cytochrome P450 2D6 (EC 1.14.14.1) (CYPIID6) (P450-DB1)| (Debrisoquine 4-hydroxylase) Length = 497 Score = 60.8 bits (146), Expect = 2e-09 Identities = 33/90 (36%), Positives = 51/90 (56%) Frame = -3 Query: 474 DLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPNALLSFSS 295 D+EV G ++PKGT + ++++ +D+ VW E F P F + K P A L FS+ Sbjct: 381 DIEVQGFRIPKGTTLITNLSSVLKDEAVW-EKPFRFHPEHFLDAQGHFVK-PEAFLPFSA 438 Query: 294 GPRSCIGQNFAMIEAKAVIAMILQRFSFSL 205 G R+C+G+ A +E +LQ FSFS+ Sbjct: 439 GRRACLGEPLARMELFLFFTSLLQHFSFSV 468
>C71AD_ARATH (O49342) Cytochrome P450 71A13 (EC 1.14.-.-)| Length = 497 Score = 60.8 bits (146), Expect = 2e-09 Identities = 35/96 (36%), Positives = 52/96 (54%), Gaps = 1/96 (1%) Frame = -3 Query: 495 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMR-FENGVTRAGKHP 319 + R D++V G + GT + I I RD +WG DA EFKP R ++G+ GK+ Sbjct: 368 LPRLLSEDVKVKGYNIAAGTEVIINAWAIQRDTAIWGPDAEEFKPERHLDSGLDYHGKNL 427 Query: 318 NALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSF 211 N + F SG R C G N A+ A+ +A ++ RF + Sbjct: 428 N-YIPFGSGRRICPGINLALGLAEVTVANLVGRFDW 462
>CP4E5_DROMT (O44221) Cytochrome P450 4e5, mitochondrial precursor (EC 1.14.-.-)| (CYPIVE5) Length = 522 Score = 60.8 bits (146), Expect = 2e-09 Identities = 34/93 (36%), Positives = 52/93 (55%) Frame = -3 Query: 495 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPN 316 I R D + G +PKGT + + I + D V+ E+ + F P RFE + P Sbjct: 377 IGRYTDKDYNIHGTIMPKGTTLNLGIIVLGYDDRVF-EEPHRFYPERFE----KQKPGPF 431 Query: 315 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRF 217 + FS+GPR+CIGQ FA++E K VI+ +++ F Sbjct: 432 EYVPFSAGPRNCIGQKFALLELKTVISKLVRTF 464
>C28D2_DROME (Q9VMT6) Probable cytochrome P450 28d2 (EC 1.14.-.-) (CYPXXVIIID2)| Length = 501 Score = 60.8 bits (146), Expect = 2e-09 Identities = 31/90 (34%), Positives = 48/90 (53%), Gaps = 3/90 (3%) Frame = -3 Query: 456 IKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRF---ENGVTRAGKHPNALLSFSSGPR 286 + + G V+TIP+ +H D + + ED FKP RF G ++ + L+F GPR Sbjct: 386 VHLKPGDVVTIPVKALHHDPQYY-EDPLTFKPERFLESNGGGMKSYRDRGVYLAFGDGPR 444 Query: 285 SCIGQNFAMIEAKAVIAMILQRFSFSLSPK 196 C G FA+ + KA + IL+ F ++PK Sbjct: 445 HCPGMRFALTQLKAALVEILRNFEIKVNPK 474
>C135A_MYCTU (O08447) Putative cytochrome P450 135A1 (EC 1.14.-.-)| Length = 449 Score = 60.8 bits (146), Expect = 2e-09 Identities = 41/120 (34%), Positives = 58/120 (48%), Gaps = 2/120 (1%) Frame = -3 Query: 501 AAIQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKH 322 A+ RK + E+GG ++P GTV+ I H EV EF+P RF +G Sbjct: 315 ASTARKVTAPAEIGGWRLPAGTVVNTSILLAHAS-EVSHPKPTEFRPSRFLDGSVA---- 369 Query: 321 PNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLS-PKYVHAPM-DVITLRPKFG 148 PN L F G R C+G FA+ E ++ I +RF+ + + P P+ IT PK G Sbjct: 370 PNTWLPFGGGVRRCLGFGFALTEGAVILQEIFRRFTITAAGPSKGETPLVRNITTVPKHG 429
>CP2D6_PANPA (Q2XNC9) Cytochrome P450 2D6 (EC 1.14.14.1) (CYPIID6)| Length = 497 Score = 60.5 bits (145), Expect = 3e-09 Identities = 33/90 (36%), Positives = 51/90 (56%) Frame = -3 Query: 474 DLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPNALLSFSS 295 D+EV G ++PKGT + ++++ +D+ VW E F P F + K P A L FS+ Sbjct: 381 DIEVQGFRIPKGTTLFTNLSSVLKDEAVW-EKPFRFHPEHFLDAQGHFVK-PEAFLPFSA 438 Query: 294 GPRSCIGQNFAMIEAKAVIAMILQRFSFSL 205 G R+C+G+ A +E +LQ FSFS+ Sbjct: 439 GRRACLGEPLARMELFLFFTSLLQHFSFSV 468
>CP52I_CANMA (Q12586) Cytochrome P450 52A9 (EC 1.14.14.-) (CYPLIIA9)| (Alkane-inducible P450-ALK5-A) Length = 521 Score = 60.5 bits (145), Expect = 3e-09 Identities = 36/99 (36%), Positives = 52/99 (52%), Gaps = 1/99 (1%) Frame = -3 Query: 456 IKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPNALLSFSSGPRSCI 277 I + KG V++ I + H D +G DA F P R+ T+ K A L F+ GPR C+ Sbjct: 412 IFIKKGAVVSYGINSTHLDPMYYGPDARLFNPDRWSKPETK--KLGWAFLPFNGGPRICL 469 Query: 276 GQNFAMIEAKAVIAMILQRF-SFSLSPKYVHAPMDVITL 163 GQ FA+ EA V+ ++Q F L+P V+ P + L Sbjct: 470 GQQFALTEASYVLVRMIQNFKELELTPNTVYPPRRLTNL 508
>C86A2_ARATH (O23066) Cytochrome P450 86A2 (EC 1.14.-.-)| Length = 553 Score = 60.5 bits (145), Expect = 3e-09 Identities = 38/114 (33%), Positives = 59/114 (51%), Gaps = 4/114 (3%) Frame = -3 Query: 474 DLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPN----ALL 307 D+ G VP G+ +T I R K WGED EFKP R+ + GK N + Sbjct: 393 DILPDGTFVPAGSSVTYSIYAAGRMKSTWGEDCLEFKPERWIS--PDDGKFVNHDQYRFV 450 Query: 306 SFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITLRPKFGL 145 +F++GPR C+G++ A ++ K + A +L R +++P + +TL K GL Sbjct: 451 AFNAGPRICLGKDLAYLQMKTIAAAVLLRHRLTVAPGHKVEQKMSLTLFMKNGL 504
>CP2DG_CAVPO (Q64403) Cytochrome P450 2D16 (EC 1.14.14.1) (CYPIID16)| Length = 500 Score = 60.5 bits (145), Expect = 3e-09 Identities = 34/90 (37%), Positives = 51/90 (56%) Frame = -3 Query: 474 DLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPNALLSFSS 295 D EV G +PKGT++ ++++ +D+ VW E F P F + R K A + FS+ Sbjct: 384 DTEVQGFLIPKGTMLFTNLSSVLKDETVW-EKPLHFHPGHFLDAEGRFVKR-EAFMPFSA 441 Query: 294 GPRSCIGQNFAMIEAKAVIAMILQRFSFSL 205 GPR C+G+ A +E +LQRFSFS+ Sbjct: 442 GPRICLGEPLARMELFLFFTSLLQRFSFSV 471
>CP17A_RAT (P11715) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 507 Score = 60.1 bits (144), Expect = 3e-09 Identities = 35/102 (34%), Positives = 51/102 (50%), Gaps = 4/102 (3%) Frame = -3 Query: 495 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKH-- 322 I KA D +G VPK T + + + +H D+ W + ++F P RF + G H Sbjct: 370 IPHKANVDSSIGEFTVPKDTHVVVNLWALHHDENEW-DQPDQFMPERF---LDPTGSHLI 425 Query: 321 --PNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLS 202 + L F +GPRSCIG+ A E A++LQRF +S Sbjct: 426 TPTQSYLPFGAGPRSCIGEALARQELFVFTALLLQRFDLDVS 467
>CP2DJ_CALJA (O18992) Cytochrome P450 2D19 (EC 1.14.14.1) (CYPIID19) (P450| CM2D-1) Length = 497 Score = 60.1 bits (144), Expect = 3e-09 Identities = 34/90 (37%), Positives = 51/90 (56%) Frame = -3 Query: 474 DLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPNALLSFSS 295 D+EV G +PKGT + ++++ +D+ W E F P F + R K P A L FS+ Sbjct: 381 DIEVQGFLIPKGTTLFTNLSSVLKDEANW-EKPFRFHPEHFLDAQGRFVK-PEAFLPFSA 438 Query: 294 GPRSCIGQNFAMIEAKAVIAMILQRFSFSL 205 G R+C+G+ A +E +LQRFSFS+ Sbjct: 439 GRRACLGEPLARMELFLFFTCLLQRFSFSV 468
>C81E1_GLYEC (P93147) Cytochrome P450 81E1 (EC 1.14.13.89) (Isoflavone| 2'-hydroxylase) (P450 91A4) (CYP GE-3) Length = 499 Score = 60.1 bits (144), Expect = 3e-09 Identities = 41/125 (32%), Positives = 61/125 (48%), Gaps = 2/125 (1%) Frame = -3 Query: 495 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPN 316 + + +GG KVP+ T++ I IHRD E+W E A FKP RFE + G+ Sbjct: 371 LPHSTSDECNIGGYKVPQDTIVLINAWAIHRDPELWTE-ATTFKPERFE----KKGE-LE 424 Query: 315 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSL--SPKYVHAPMDVITLRPKFGLP 142 L++F G R+C G+ A+ +A+++Q F + L K A D TL L Sbjct: 425 KLIAFGMGRRACPGEGLAIRAISMTLALLIQCFDWKLINGDKIDLAERDGFTLTKLVPLK 484 Query: 141 MILKS 127 + KS Sbjct: 485 AMCKS 489
>C4AC1_DROME (Q9VMS9) Probable cytochrome P450 4ac1 (EC 1.14.-.-) (CYPIVAC1)| Length = 509 Score = 60.1 bits (144), Expect = 3e-09 Identities = 38/95 (40%), Positives = 57/95 (60%), Gaps = 2/95 (2%) Frame = -3 Query: 495 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRF--ENGVTRAGKH 322 I R+ + V G+ +PK T I+I I I RD + + + F+P RF EN V R H Sbjct: 385 IGRQCVEETVVNGMVMPKDTQISIHIYDIMRDPRHFPKP-DLFQPDRFLPENTVNR---H 440 Query: 321 PNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRF 217 P A + FS+G R+CIGQ FA++E K ++A +++ F Sbjct: 441 PFAYVPFSAGQRNCIGQKFAILEMKVLLAAVIRNF 475
>CP4F3_HUMAN (Q08477) Cytochrome P450 4F3 (EC 1.14.13.30) (CYPIVF3)| (Leukotriene-B(4) omega-hydroxylase) (Leukotriene-B(4) 20-monooxygenase) (Cytochrome P450-LTB-omega) Length = 520 Score = 60.1 bits (144), Expect = 3e-09 Identities = 35/95 (36%), Positives = 51/95 (53%), Gaps = 1/95 (1%) Frame = -3 Query: 498 AIQRKAGSDLEV-GGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKH 322 A+ R D+ + G +PKG + I + H + VW D + P RF+ + + Sbjct: 397 AVSRCCTQDIVLPDGRVIPKGIICLISVFGTHHNPAVW-PDPEVYDPFRFDPKNIKE-RS 454 Query: 321 PNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRF 217 P A + FS+GPR+CIGQ FAM E K V+ + L RF Sbjct: 455 PLAFIPFSAGPRNCIGQAFAMAEMKVVLGLTLLRF 489
>CP4E1_DROME (Q9V4T5) Probable cytochrome P450 4e1 (EC 1.14.-.-) (CYPIVE1)| Length = 531 Score = 59.7 bits (143), Expect = 4e-09 Identities = 33/93 (35%), Positives = 54/93 (58%) Frame = -3 Query: 495 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPN 316 I R D + G VPKGT + + + + + V+ +D ++F+P RF+ R P Sbjct: 378 IGRFTEKDYVIDGDIVPKGTTLNLGLLMLGYNDRVF-KDPHKFQPERFD----REKPGPF 432 Query: 315 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRF 217 + FS+GPR+CIGQ FA++E K V++ I++ F Sbjct: 433 EYVPFSAGPRNCIGQKFALLEIKTVVSKIIRNF 465
>CP4D8_DROME (Q9VS79) Cytochrome P450 4d8 (EC 1.14.-.-) (CYPIVD8)| Length = 463 Score = 59.7 bits (143), Expect = 4e-09 Identities = 36/104 (34%), Positives = 59/104 (56%) Frame = -3 Query: 450 VPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPNALLSFSSGPRSCIGQ 271 +P G+ I I I +HR E + + +EF P R ENG A P ++ FS+GPR+CIGQ Sbjct: 357 IPAGSEIIIGIFGVHRQPETF-PNPDEFIPERHENGSRVA---PFKMIPFSAGPRNCIGQ 412 Query: 270 NFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITLRPKFGLPM 139 FA +E K ++A I++ + + V ++++ LR + G + Sbjct: 413 KFAQLEMKMMLAKIVREYELLPMGQRVECIVNIV-LRSETGFQL 455
>CP2DH_MACFA (Q29488) Cytochrome P450 2D17 (EC 1.14.14.1) (CYPIID17)| Length = 497 Score = 59.7 bits (143), Expect = 4e-09 Identities = 33/90 (36%), Positives = 51/90 (56%) Frame = -3 Query: 474 DLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPNALLSFSS 295 D+E+ G +PKGT + ++++ +D+ VW E F P F + K P A L FS+ Sbjct: 381 DIELQGFLIPKGTTLFTNLSSVLKDEAVW-EKPFRFHPEHFLDAQGHFVK-PEAFLPFSA 438 Query: 294 GPRSCIGQNFAMIEAKAVIAMILQRFSFSL 205 G R+C+G+ A +E +LQRFSFS+ Sbjct: 439 GRRACLGEPLARMELFLFFTCLLQRFSFSV 468
>C4AC2_DROME (Q9VMS8) Probable cytochrome P450 4ac2 (EC 1.14.-.-) (CYPIVAC2)| Length = 497 Score = 59.7 bits (143), Expect = 4e-09 Identities = 37/95 (38%), Positives = 55/95 (57%), Gaps = 2/95 (2%) Frame = -3 Query: 495 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRF--ENGVTRAGKH 322 I R+ + V G+ +PK T I I + I RD + + F+P RF EN V R H Sbjct: 372 IGRRCVEEGVVNGLIMPKNTQINIHLYEIMRDARHFS-NPKMFQPDRFFPENTVNR---H 427 Query: 321 PNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRF 217 P A + FS+G R+CIGQ FA++E K ++A +++ F Sbjct: 428 PFAFVPFSAGQRNCIGQKFAILEIKVLLAAVIRNF 462
>C4G15_DROME (Q9VYY4) Cytochrome P450 4g15 (EC 1.14.-.-) (CYPIVG15)| Length = 574 Score = 59.7 bits (143), Expect = 4e-09 Identities = 31/99 (31%), Positives = 57/99 (57%), Gaps = 6/99 (6%) Frame = -3 Query: 495 IQRKAGSDLEV--GGIKVPKGTVITIPIATIHRDKEVWGE----DANEFKPMRFENGVTR 334 I R+ DL++ G +P+G +T+ +HR+ +V+ D + F P R + Sbjct: 448 IARELQEDLKLNSGNYVIPRGATVTVATVLLHRNPKVYANPNVFDPDNFLPER------Q 501 Query: 333 AGKHPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRF 217 A +H A + FS+GPRSC+G+ +AM++ K +++ IL+ + Sbjct: 502 ANRHYYAFVPFSAGPRSCVGRKYAMLKLKILLSTILRNY 540
>CP191_CARAU (P79690) Cytochrome P450 19 type 1 (EC 1.14.14.1) (Brain aromatase)| (CYPXIXA1) (Estrogen synthetase) (P-450AROM) Length = 510 Score = 59.3 bits (142), Expect = 6e-09 Identities = 33/94 (35%), Positives = 52/94 (55%) Frame = -3 Query: 495 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPN 316 I R+A D E+ G +V KGT + + I +H+ + + + NEF FEN V P Sbjct: 371 IMRRALEDDEIDGYRVAKGTNLILNIGRMHKSE--FFQKPNEFNLENFENTVPSRYFQP- 427 Query: 315 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFS 214 F GPR+C+G++ AM+ KA++ +L RF+ Sbjct: 428 ----FGCGPRACVGKHIAMVMTKAILVTLLSRFT 457
>C4D20_DROME (Q9W011) Probable cytochrome P450 4d20 (EC 1.14.-.-) (CYPIVD20)| Length = 510 Score = 59.3 bits (142), Expect = 6e-09 Identities = 34/92 (36%), Positives = 53/92 (57%) Frame = -3 Query: 498 AIQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHP 319 AI R A +LE+G +P T I + + HRD + D F+P RF + G + Sbjct: 385 AIGRHAQKELEIGDKTIPANTSIYLVLYYAHRDANYF-PDPLSFRPERFLEDQEQ-GHNT 442 Query: 318 NALLSFSSGPRSCIGQNFAMIEAKAVIAMILQ 223 A + FS+GP++CIGQ FA++E K +I+ +L+ Sbjct: 443 FAYVPFSAGPKNCIGQKFAVLEMKVLISKVLR 474
>CP2D9_MOUSE (P11714) Cytochrome P450 2D9 (EC 1.14.14.1) (CYPIID9)| (P450-16-alpha) (CA) (Testosterone 16-alpha hydroxylase) Length = 504 Score = 59.3 bits (142), Expect = 6e-09 Identities = 34/97 (35%), Positives = 53/97 (54%) Frame = -3 Query: 495 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPN 316 + R D+EV +PKGT++ ++++ +D+ VW E F P F + K P Sbjct: 377 LPRITSHDIEVQDFLIPKGTILLPNMSSMLKDESVW-EKPLRFHPEHFLDAQGHFVK-PE 434 Query: 315 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSL 205 A + FS+G RSC+G+ A +E +LQRFSFS+ Sbjct: 435 AFMPFSAGRRSCLGEALARMELFLFFTCLLQRFSFSV 471
>C505_FUSOX (Q9Y8G7) Bifunctional P-450:NADPH-P450 reductase (Fatty acid| omega-hydroxylase) (P450foxy) [Includes: Cytochrome P450 505 (EC 1.14.14.1); NADPH--cytochrome P450 reductase (EC 1.6.2.4)] Length = 1066 Score = 59.3 bits (142), Expect = 6e-09 Identities = 34/105 (32%), Positives = 58/105 (55%), Gaps = 3/105 (2%) Frame = -3 Query: 462 GGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRF-ENGVTRAGK-HPNALLSFSSGP 289 G V KG ++T ++ H D V+G DA++F P R ++ R K +PN F +G Sbjct: 345 GKYLVKKGEIVTALLSRGHVDPVVYGNDADKFIPERMLDDEFARLNKEYPNCWKPFGNGK 404 Query: 288 RSCIGQNFAMIEAKAVIAMILQRFSFSLS-PKYVHAPMDVITLRP 157 R+CIG+ FA E+ + ++ Q F+F+++ P Y +T++P Sbjct: 405 RACIGRPFAWQESLLAMVVLFQNFNFTMTDPNYALEIKQTLTIKP 449
>CP2DA_RAT (P12939) Cytochrome P450 2D10 (EC 1.14.14.1) (CYPIID10) (P450-DB5)| (P450-CMF1B) (Debrisoquine 4-hydroxylase) Length = 504 Score = 58.9 bits (141), Expect = 7e-09 Identities = 33/97 (34%), Positives = 52/97 (53%) Frame = -3 Query: 495 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPN 316 + R D+EV +PKGT + I ++++ +D+ VW E F P F + KH Sbjct: 377 LPRITSCDIEVQDFVIPKGTTLIINLSSVLKDETVW-EKPLRFHPEHFLDAQGNFVKH-E 434 Query: 315 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSL 205 A + FS+G R+C+G+ A +E +LQ FSFS+ Sbjct: 435 AFMPFSAGRRACLGEPLARMELFLFFTCLLQHFSFSV 471
>C71AM_ARATH (Q9STL1) Cytochrome P450 71A22 (EC 1.14.-.-)| Length = 490 Score = 58.9 bits (141), Expect = 7e-09 Identities = 30/108 (27%), Positives = 53/108 (49%) Frame = -3 Query: 495 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPN 316 + ++ D+ +G +P GT + I I R+ WG DA +F+P R N H Sbjct: 361 VPHESTQDVRLGDYHIPAGTQVMINAWAIGREAATWGPDAEKFRPERHLNSSVDFRGHNF 420 Query: 315 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDV 172 L+ F +G R C +FA+I + +A ++ R+ + L +Y+ +V Sbjct: 421 ELIPFGAGRRICPAISFAVILIEVTLANLVHRYDWRLPEEYIEDQTNV 468
>C6A18_DROME (Q9VB31) Probable cytochrome P450 6a18 (EC 1.14.-.-) (CYPVIA18)| Length = 507 Score = 58.5 bits (140), Expect = 1e-08 Identities = 31/82 (37%), Positives = 48/82 (58%), Gaps = 1/82 (1%) Frame = -3 Query: 450 VPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPN-ALLSFSSGPRSCIG 274 + G + IP + IH D ++ E NEF+P RF + K P+ A L F GPR+CIG Sbjct: 397 IEAGQSVIIPSSAIHHDPSIYPEP-NEFRPERFSP--EESAKRPSVAWLPFGEGPRNCIG 453 Query: 273 QNFAMIEAKAVIAMILQRFSFS 208 F ++A+ +AM+++ F+FS Sbjct: 454 LRFGQMQARIGLAMLIKNFTFS 475
>C83B1_ARATH (O65782) Cytochrome P450 83B1 (EC 1.14.-.-)| Length = 499 Score = 58.5 bits (140), Expect = 1e-08 Identities = 39/116 (33%), Positives = 59/116 (50%), Gaps = 6/116 (5%) Frame = -3 Query: 495 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFEN---GVTRAGK 325 + R+ +D ++GG +P T+I + + RD WG++ NEF P RF N GV G+ Sbjct: 368 LHRETIADAKIGGYDIPAKTIIQVNAWAVSRDTAAWGDNPNEFIPERFMNEHKGVDFKGQ 427 Query: 324 HPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYV---HAPMDVIT 166 LL F SG R C + + + A +L +F +SL PK + MDV+T Sbjct: 428 -DFELLPFGSGRRMCPAMHLGIAMVEIPFANLLYKFDWSL-PKGIKPEDIKMDVMT 481
>CP2DK_MESAU (Q9QYG5) Cytochrome P450 2D20 (EC 1.14.14.-) (CYPIID20)| Length = 500 Score = 58.5 bits (140), Expect = 1e-08 Identities = 33/90 (36%), Positives = 51/90 (56%) Frame = -3 Query: 474 DLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPNALLSFSS 295 D+EV G +PKGT + ++++ +D+ VW E F P F + R K A + FS+ Sbjct: 384 DVEVQGFLIPKGTTLIPNLSSVLKDETVW-EKPLHFHPEHFLDAQGRFVKQ-EAFMPFSA 441 Query: 294 GPRSCIGQNFAMIEAKAVIAMILQRFSFSL 205 G R+C+G+ A +E +LQRFSFS+ Sbjct: 442 GRRACLGEPLARMELFLFFTCLLQRFSFSV 471
>CP6L1_BLAGE (Q9GQM9) Cytochrome P450 6l1 (EC 1.14.-.-) (CYPVIL1)| Length = 503 Score = 58.5 bits (140), Expect = 1e-08 Identities = 33/93 (35%), Positives = 50/93 (53%), Gaps = 2/93 (2%) Frame = -3 Query: 495 IQRKAGSDLEVGG--IKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKH 322 I R D + G + + KGT I + + +HRD ++ D +F P RF N ++G H Sbjct: 367 IDRVCLHDYHIPGTDVVIEKGTPIFVSLLGLHRDS-IFYPDPEDFNPERF-NKEKKSGVH 424 Query: 321 PNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQ 223 P + + F GPR+CIG ++ K VI M+LQ Sbjct: 425 PFSYIPFGDGPRNCIGLRLGLMSVKLVIIMLLQ 457
>C6A17_DROME (Q9V770) Probable cytochrome P450 6a17 (EC 1.14.-.-) (CYPVIA17)| Length = 501 Score = 58.2 bits (139), Expect = 1e-08 Identities = 32/94 (34%), Positives = 52/94 (55%) Frame = -3 Query: 450 VPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPNALLSFSSGPRSCIGQ 271 + KGT++ IP IH D +++ E FKP RF + A + L F GPR+CIG Sbjct: 390 IAKGTIVVIPALGIHYDPDIYPEP-EIFKPERFTDEEI-AARPSCTWLPFGEGPRNCIGL 447 Query: 270 NFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVI 169 F M++ +A +++ + FS+SP+ PM ++ Sbjct: 448 RFGMMQTCVGLAYLIRGYKFSVSPE-TQIPMKIV 480
>CP1A1_MOUSE (P00184) Cytochrome P450 1A1 (EC 1.14.14.1) (CYPIA1) (P450-P1)| Length = 524 Score = 58.2 bits (139), Expect = 1e-08 Identities = 36/130 (27%), Positives = 63/130 (48%), Gaps = 1/130 (0%) Frame = -3 Query: 474 DLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPNALLS-FS 298 D + G +PKG + + ++ D+E+WG D NEF+P RF K + ++ F Sbjct: 397 DTSLNGFYIPKGCCVFVNQWQVNHDRELWG-DPNEFRPERFLTPSGTLDKRLSEKVTLFG 455 Query: 297 SGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITLRPKFGLPMILKSLEM 118 G R CIG+ E +A++LQ+ F +SP + + + P +GL +L+ Sbjct: 456 LGKRKCIGETIGRSEVFLFLAILLQQIEFKVSPG------EKVDMTPTYGL-----TLKH 504 Query: 117 *RCVEYNTRL 88 RC + ++ Sbjct: 505 ARCEHFQVQM 514
>C4AD1_DROME (Q9V4T3) Probable cytochrome P450 4ad1 (EC 1.14.-.-) (CYPIVAD1)| Length = 516 Score = 58.2 bits (139), Expect = 1e-08 Identities = 35/94 (37%), Positives = 53/94 (56%), Gaps = 1/94 (1%) Frame = -3 Query: 495 IQRKAGSDLEVGGIKVPK-GTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHP 319 I R + +++ G KV K TVI IA + +K + +D F+P RFEN G Sbjct: 375 IARTNRNPIDINGTKVAKCTTVIMCLIAMGYNEK--YFDDPCTFRPERFENPTGNVGIEA 432 Query: 318 NALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRF 217 + FS+GPR CI + FAM + KA+++ +L+RF Sbjct: 433 FKSVPFSAGPRRCIAEKFAMYQMKALLSQLLRRF 466
>CP2J6_MOUSE (O54750) Cytochrome P450 2J6 (EC 1.14.14.1) (CYPIIJ6) (Arachidonic| acid epoxygenase) Length = 501 Score = 57.8 bits (138), Expect = 2e-08 Identities = 34/108 (31%), Positives = 54/108 (50%), Gaps = 7/108 (6%) Frame = -3 Query: 495 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRF-ENGVTRAGKHP 319 + R+ D + G +PKGT++ + +HRD + W + F P F ENG K Sbjct: 379 VPREVAMDTNLNGFHLPKGTMVLTNLTALHRDPKEWA-TPDVFNPEHFLENG---QFKKR 434 Query: 318 NALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFS------LSPKY 193 + L FS G R+C+G+ A E ++Q+F+F+ LSPK+ Sbjct: 435 ESFLPFSMGKRACLGEQLARSELFIFFTSLMQKFTFNPPINEKLSPKF 482
>CP17A_PANTR (Q8HYN1) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 508 Score = 57.8 bits (138), Expect = 2e-08 Identities = 34/98 (34%), Positives = 52/98 (53%), Gaps = 1/98 (1%) Frame = -3 Query: 495 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPN 316 I KA D +G V KGT + I + +H +++ W + ++F P RF N P+ Sbjct: 371 IPHKANVDSSIGEFAVDKGTQVIINLWALHHNEKEWHQP-DQFMPERFLNPAGTQLISPS 429 Query: 315 -ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSL 205 + L F +GPRSCIG+ A E ++A +LQRF + Sbjct: 430 VSYLPFGAGPRSCIGEILARQELFLIMAWLLQRFDLEV 467
>CP17A_HUMAN (P05093) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-monooxygenase) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 508 Score = 57.8 bits (138), Expect = 2e-08 Identities = 34/98 (34%), Positives = 52/98 (53%), Gaps = 1/98 (1%) Frame = -3 Query: 495 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPN 316 I KA D +G V KGT + I + +H +++ W + ++F P RF N P+ Sbjct: 371 IPHKANVDSSIGEFAVDKGTEVIINLWALHHNEKEWHQP-DQFMPERFLNPAGTQLISPS 429 Query: 315 -ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSL 205 + L F +GPRSCIG+ A E ++A +LQRF + Sbjct: 430 VSYLPFGAGPRSCIGEILARQELFLIMAWLLQRFDLEV 467
>C76C3_ARATH (O64638) Cytochrome P450 76C3 (EC 1.14.-.-)| Length = 515 Score = 57.8 bits (138), Expect = 2e-08 Identities = 39/119 (32%), Positives = 58/119 (48%) Frame = -3 Query: 495 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPN 316 I RK+ SD+++ G VPK T + + + I RD VW E+ +F+P RF T Sbjct: 381 IPRKSESDVQIMGFLVPKNTQVVVNVWAIGRDASVW-ENPMKFEPERFLLRETDVKGRDF 439 Query: 315 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITLRPKFGLPM 139 L+ F SG R C G + A+ V+A +L F + L V +D + FGL + Sbjct: 440 ELIPFGSGRRMCPGISMALKTMHMVLASLLYSFDWKLQNGVVPGNID---MSETFGLTL 495
>CP46A_MOUSE (Q9WVK8) Cytochrome p450 46A1 (EC 1.14.13.98) (Cholesterol| 24-hydroxylase) (CH24H) Length = 500 Score = 57.8 bits (138), Expect = 2e-08 Identities = 38/103 (36%), Positives = 50/103 (48%) Frame = -3 Query: 465 VGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPNALLSFSSGPR 286 + G++VP T + + R + + ED F P RF G A K FS G R Sbjct: 380 IDGVRVPGNTPLLFSTYVMGR-MDTYFEDPLTFNPDRFGPG---APKPRFTYFPFSLGHR 435 Query: 285 SCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITLRP 157 SCIGQ FA +E K V+A +LQR F L P + TL+P Sbjct: 436 SCIGQQFAQMEVKVVMAKLLQRIEFRLVPGQRFGLQEQATLKP 478
>CP46A_HUMAN (Q9Y6A2) Cytochrome p450 46A1 (EC 1.14.13.98) (Cholesterol| 24-hydroxylase) (CH24H) Length = 500 Score = 57.8 bits (138), Expect = 2e-08 Identities = 38/103 (36%), Positives = 50/103 (48%) Frame = -3 Query: 465 VGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPNALLSFSSGPR 286 + G++VP T + + R + + ED F P RF G A K FS G R Sbjct: 380 IDGVRVPGNTPLLFSTYVMGR-MDTYFEDPLTFNPDRFGPG---APKPRFTYFPFSLGHR 435 Query: 285 SCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITLRP 157 SCIGQ FA +E K V+A +LQR F L P + TL+P Sbjct: 436 SCIGQQFAQMEVKVVMAKLLQRLEFRLVPGQRFGLQEQATLKP 478
>CP136_MYCTU (P95099) Putative cytochrome P450 136 (EC 1.14.-.-)| Length = 492 Score = 57.4 bits (137), Expect = 2e-08 Identities = 37/125 (29%), Positives = 58/125 (46%), Gaps = 5/125 (4%) Frame = -3 Query: 489 RKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPNAL 310 R+ D E+ G +PKGT + HR E+W D F P RF +H A Sbjct: 371 RQTVRDTELLGYYLPKGTNVIAYPGMNHRLPEIW-TDPLTFDPERFTEPRNEHKRHRYAF 429 Query: 309 LSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLS-----PKYVHAPMDVITLRPKFGL 145 F G CIG F +E K ++ +L+R+ LS P++ ++ M + P G+ Sbjct: 430 TPFGGGVHKCIGMVFDQLEIKTILHRLLRRYRLELSRPDYQPRWDYSAMPI----PMDGM 485 Query: 144 PMILK 130 P++L+ Sbjct: 486 PIVLR 490
>CP1A1_RABIT (P05176) Cytochrome P450 1A1 (EC 1.14.14.1) (CYPIA1) (P450 isozyme| 6) (P-450 PHPAH1) (P450 LM6) Length = 518 Score = 57.4 bits (137), Expect = 2e-08 Identities = 38/116 (32%), Positives = 56/116 (48%), Gaps = 4/116 (3%) Frame = -3 Query: 474 DLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPNAL----L 307 D +GG +PKG + + + D E+WG D F+P RF +T +G AL L Sbjct: 397 DTSLGGFYIPKGRCVFVNQWQNNHDPELWG-DPEAFRPERF---LTPSGAVDKALTEKVL 452 Query: 306 SFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITLRPKFGLPM 139 F G R CIG+ +E +A +LQ+ FS+SP + + P +GL M Sbjct: 453 LFGLGKRKCIGETIGRLEVFLFLATLLQQVEFSVSPG------TTVDMTPIYGLTM 502
>CP52Q_CANMA (Q12587) Cytochrome P450 52C2 (EC 1.14.14.-) (CYPLIIC2)| (Alkane-inducible P450-ALK6-A) Length = 510 Score = 57.4 bits (137), Expect = 2e-08 Identities = 33/96 (34%), Positives = 50/96 (52%) Frame = -3 Query: 456 IKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPNALLSFSSGPRSCI 277 I V KG + P+ +R ++ +G EF P R+ + G A + FS+GPR C+ Sbjct: 403 ILVKKGDQVLFPLYASNRQEKYFGRKPEEFIPERWRDLPKTGGP---AFMPFSTGPRMCL 459 Query: 276 GQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVI 169 GQ FA+IEA V ++Q FS S +AP ++ Sbjct: 460 GQQFALIEASYVTIRLVQTFSKLKSHSLEYAPKRLV 495
>CP2R1_HUMAN (Q6VVX0) Cytochrome P450 2R1 (EC 1.14.14.-) (Vitamin D| 25-hydroxylase) Length = 501 Score = 57.4 bits (137), Expect = 2e-08 Identities = 35/113 (30%), Positives = 58/113 (51%), Gaps = 1/113 (0%) Frame = -3 Query: 474 DLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPNALLSFSS 295 D V G +PKGT + + ++H D++ W D F P RF + K AL+ FS Sbjct: 386 DAVVRGYSIPKGTTVITNLYSVHFDEKYW-RDPEVFHPERFLDSSGYFAKK-EALVPFSL 443 Query: 294 GPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVI-TLRPKFGLPM 139 G R C+G++ A +E +LQRF ++H P +++ L+P+ G+ + Sbjct: 444 GRRHCLGEHLARMEMFLFFTALLQRF-------HLHFPHELVPDLKPRLGMTL 489
>CP17A_PAPHU (Q9GLD2) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 508 Score = 57.4 bits (137), Expect = 2e-08 Identities = 34/98 (34%), Positives = 52/98 (53%), Gaps = 1/98 (1%) Frame = -3 Query: 495 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPN 316 I KA D +G V KGT + I + +H +++ W + ++F P RF N P+ Sbjct: 371 IPHKANVDSSIGEFAVDKGTHVIINLWALHHNEKEWHQP-DQFMPERFLNPAGTQLISPS 429 Query: 315 -ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSL 205 + L F +GPRSCIG+ A E ++A +LQRF + Sbjct: 430 LSYLPFGAGPRSCIGEILARQELFLIMAWLLQRFDLEV 467
>CP17A_PAPCY (Q8HYN0) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 508 Score = 57.4 bits (137), Expect = 2e-08 Identities = 34/98 (34%), Positives = 52/98 (53%), Gaps = 1/98 (1%) Frame = -3 Query: 495 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPN 316 I KA D +G V KGT + I + +H +++ W + ++F P RF N P+ Sbjct: 371 IPHKANVDSSIGEFAVDKGTHVIINLWALHHNEKEWHQP-DQFMPERFLNPAGTQLISPS 429 Query: 315 -ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSL 205 + L F +GPRSCIG+ A E ++A +LQRF + Sbjct: 430 LSYLPFGAGPRSCIGEILARQELFLIMAWLLQRFDLEV 467
>CP17A_MACMU (Q8HYM9) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 508 Score = 57.4 bits (137), Expect = 2e-08 Identities = 34/98 (34%), Positives = 52/98 (53%), Gaps = 1/98 (1%) Frame = -3 Query: 495 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPN 316 I KA D +G V KGT + I + +H +++ W + ++F P RF N P+ Sbjct: 371 IPHKANVDSSIGEFAVDKGTHVIINLWALHHNEKEWHQP-DQFMPERFLNPAGTQLISPS 429 Query: 315 -ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSL 205 + L F +GPRSCIG+ A E ++A +LQRF + Sbjct: 430 LSYLPFGAGPRSCIGEILARQELFLIMAWLLQRFDLEV 467
>CP17A_MACFA (Q2XVA1) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 508 Score = 57.4 bits (137), Expect = 2e-08 Identities = 34/98 (34%), Positives = 52/98 (53%), Gaps = 1/98 (1%) Frame = -3 Query: 495 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPN 316 I KA D +G V KGT + I + +H +++ W + ++F P RF N P+ Sbjct: 371 IPHKANVDSSIGEFAVDKGTHVIINLWALHHNEKEWHQP-DQFMPERFLNPAGTQLISPS 429 Query: 315 -ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSL 205 + L F +GPRSCIG+ A E ++A +LQRF + Sbjct: 430 LSYLPFGAGPRSCIGEILARQELFLIMAWLLQRFDLEV 467
>CP2DF_CANFA (Q29473) Cytochrome P450 2D15 (EC 1.14.14.1) (CYPIID15) (P450 DUT2)| Length = 499 Score = 57.4 bits (137), Expect = 2e-08 Identities = 32/90 (35%), Positives = 50/90 (55%) Frame = -3 Query: 474 DLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPNALLSFSS 295 D EV G +PKGT + ++++ +D++VW + F P F + KH A + FS+ Sbjct: 383 DTEVQGFLIPKGTTLITNLSSVLKDEKVWKKPFR-FYPEHFLDAQGHFVKH-EAFMPFSA 440 Query: 294 GPRSCIGQNFAMIEAKAVIAMILQRFSFSL 205 G R C+G+ A +E +LQRFSFS+ Sbjct: 441 GRRVCLGEPLARMELFLFFTCLLQRFSFSV 470
>CP2DS_MESAU (Q9QUJ1) Cytochrome P450 2D28 (EC 1.14.14.-) (CYPIID28)| Length = 500 Score = 57.4 bits (137), Expect = 2e-08 Identities = 36/104 (34%), Positives = 55/104 (52%) Frame = -3 Query: 474 DLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPNALLSFSS 295 D+EV G +PKGT + ++++ +D+ VW E F P F + K A + FS+ Sbjct: 384 DIEVQGFLIPKGTTLITNLSSVLKDETVW-EKPLHFHPEHFLDAQGCFVKQ-EAFMPFSA 441 Query: 294 GPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITL 163 G R+C+G+ A +E +LQRFSFS+ P P D + L Sbjct: 442 GRRACLGEPLARMELFLFFTCLLQRFSFSV-PAGQPRPSDHVVL 484
>CP304_DROME (Q9VG17) Probable cytochrome P450 304a1 (EC 1.14.-.-) (CYPCCCIVA1)| Length = 510 Score = 57.0 bits (136), Expect = 3e-08 Identities = 31/99 (31%), Positives = 47/99 (47%) Frame = -3 Query: 495 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPN 316 + KA D E+ G ++PK T++ + H D +W D +F+P RF + + + Sbjct: 384 VPHKALEDTELLGYRIPKDTIVVPSLYAFHSDARIW-SDPEQFRPERFLDADGKLCLKLD 442 Query: 315 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSP 199 L F +G R C G+ FA V A + Q F F L P Sbjct: 443 VSLPFGAGKRLCAGETFARNMLFLVTATMCQHFDFVLGP 481
>CP120_SYNY3 (Q59990) Putative cytochrome P450 120 (EC 1.14.-.-)| Length = 444 Score = 57.0 bits (136), Expect = 3e-08 Identities = 36/122 (29%), Positives = 59/122 (48%) Frame = -3 Query: 489 RKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPNAL 310 R+ D + G PKG +++ I+ H D +++ D +F P RF + P A Sbjct: 323 RELIQDCQFQGFHFPKGWLVSYQISQTHADPDLY-PDPEKFDPERFTPDGSATHNPPFAH 381 Query: 309 LSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITLRPKFGLPMILK 130 + F G R C+G+ FA +E K ++Q+F ++L P + + RPK L + L Sbjct: 382 VPFGGGLRECLGKEFARLEMKLFATRLIQQFDWTLLPGQNLELVVTPSPRPKDNLRVKLH 441 Query: 129 SL 124 SL Sbjct: 442 SL 443
>CP2DE_BOVIN (Q01361) Cytochrome P450 2D14 (EC 1.14.14.1) (CYPIID14) (Fragment)| Length = 487 Score = 57.0 bits (136), Expect = 3e-08 Identities = 31/90 (34%), Positives = 50/90 (55%) Frame = -3 Query: 474 DLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPNALLSFSS 295 D+EV G +PKGT + ++++ +D+ VW + F P F + R K A + FS+ Sbjct: 371 DIEVQGFHIPKGTTLITNLSSVLKDETVW-QKPFRFHPEHFLDAQGRFVKQ-EAFIPFSA 428 Query: 294 GPRSCIGQNFAMIEAKAVIAMILQRFSFSL 205 G R+C+G+ A +E +LQ FSFS+ Sbjct: 429 GRRACLGEPLARMELFLFFTSLLQHFSFSV 458
>C76B1_HELTU (O23976) Cytochrome P450 76B1 (EC 1.14.-.-) (7-ethoxycoumarin| O-deethylase) (ECOD) (Phenylurea dealkylase) Length = 490 Score = 57.0 bits (136), Expect = 3e-08 Identities = 35/116 (30%), Positives = 54/116 (46%) Frame = -3 Query: 495 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPN 316 + RK + +E+ G +P GT++ + I RD VW +D+ EFKP RF H Sbjct: 362 LPRKVVTQVELSGYTIPAGTLVFVNAWAIGRDPTVW-DDSLEFKPQRFLESRLDVRGHDF 420 Query: 315 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITLRPKFG 148 L+ F +G R C G A ++ +L F + + K P DV+ + K G Sbjct: 421 DLIPFGAGRRICPGIPLATRMVPIMLGSLLNNFDWKIDTK---VPYDVLDMTEKNG 473
>C6A23_DROME (Q9V771) Probable cytochrome P450 6a23 (EC 1.14.-.-) (CYPVIA23)| Length = 502 Score = 57.0 bits (136), Expect = 3e-08 Identities = 38/110 (34%), Positives = 57/110 (51%) Frame = -3 Query: 450 VPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPNALLSFSSGPRSCIGQ 271 + KGT + IP IH D E++ E +FKP RF + A + L F GPR+CIG Sbjct: 391 IAKGTTVVIPALGIHYDPEIYPEP-EKFKPERFTDEAI-AARPSCTWLPFGEGPRNCIGL 448 Query: 270 NFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITLRPKFGLPMILKSLE 121 F +++A +A +++ + FS+S + PM KF + IL S E Sbjct: 449 RFGLMQACVGLAYLIRGYKFSVSTE-TQIPM-------KFVVKSILLSAE 490
>C28D1_DROME (Q9VMT5) Probable cytochrome P450 28d1 (EC 1.14.-.-) (CYPXXVIIID1)| Length = 502 Score = 57.0 bits (136), Expect = 3e-08 Identities = 28/89 (31%), Positives = 46/89 (51%), Gaps = 2/89 (2%) Frame = -3 Query: 456 IKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFEN--GVTRAGKHPNALLSFSSGPRS 283 +K+ G V+ IP+ +H D + + E+ FKP RF N G + + F GPR Sbjct: 387 VKLRPGDVVIIPVNALHHDPQYY-EEPQSFKPERFLNINGGAKKYRDQGLFFGFGDGPRI 445 Query: 282 CIGQNFAMIEAKAVIAMILQRFSFSLSPK 196 C G F++ + KA + I++ F ++PK Sbjct: 446 CPGMRFSLTQIKAALVEIVRNFDIKVNPK 474
>CP2DQ_RAT (P10634) Cytochrome P450 2D26 (EC 1.14.14.1) (CYPIID26) (P450-DB2)| (P450-CMF2) (Debrisoquine 4-hydroxylase) Length = 500 Score = 57.0 bits (136), Expect = 3e-08 Identities = 32/97 (32%), Positives = 51/97 (52%) Frame = -3 Query: 495 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPN 316 I D++ G +PKGT + ++++ +D+ VW E F P F + KH Sbjct: 377 IPHMTSRDIKFQGFLIPKGTTLIPNLSSVLKDETVW-EKPLRFHPEHFLDAQGNFVKH-E 434 Query: 315 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSL 205 A + FS+G R+C+G+ A +E +LQRFSFS+ Sbjct: 435 AFMPFSAGRRACLGEPLARMELFLFFTCLLQRFSFSV 471
>CP6A2_DROME (P33270) Cytochrome P450 6a2 (EC 1.14.-.-) (CYPVIA2) (P450-B1)| Length = 506 Score = 57.0 bits (136), Expect = 3e-08 Identities = 34/100 (34%), Positives = 53/100 (53%), Gaps = 3/100 (3%) Frame = -3 Query: 495 IQRKAGSDLEVGG---IKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGK 325 ++RKA +D V G + + KGT + IP HRD++++ + F P RF A + Sbjct: 379 LERKALNDYVVPGHEKLVIEKGTQVIIPACAYHRDEDLY-PNPETFDPERFSPEKV-AAR 436 Query: 324 HPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSL 205 L F GPR+CIG F ++A+ +A I+ RF S+ Sbjct: 437 ESVEWLPFGDGPRNCIGMRFGQMQARIGLAQIISRFRVSV 476
>CP2J3_RAT (P51590) Cytochrome P450 2J3 (EC 1.14.14.1) (CYPIIJ3)| Length = 502 Score = 56.6 bits (135), Expect = 4e-08 Identities = 32/96 (33%), Positives = 49/96 (51%), Gaps = 1/96 (1%) Frame = -3 Query: 495 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRF-ENGVTRAGKHP 319 + R+ D + G +PKGT+I + +HRD + W + F P F ENG K Sbjct: 380 VPREVAVDTYLAGFNLPKGTMILTNLTALHRDPKEWA-TPDTFNPEHFLENG---QFKKR 435 Query: 318 NALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSF 211 + L FS G R+C+G+ A E I ++Q+F+F Sbjct: 436 ESFLPFSMGKRACLGEQLARSELFIFITSLIQKFTF 471
>CP2DP_PIG (O46658) Cytochrome P450 2D25 (EC 1.14.14.-) (CYPIID25) (Vitamin| D(3) 25-hydroxylase) Length = 499 Score = 56.6 bits (135), Expect = 4e-08 Identities = 32/90 (35%), Positives = 49/90 (54%) Frame = -3 Query: 474 DLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPNALLSFSS 295 D+EV G +PKGT + + ++ +D+ VW + F P F + R K A + FS+ Sbjct: 383 DIEVQGFLIPKGTTLITNLTSVLKDETVWKKPFR-FYPEHFLDAQGRFTKQ-EAFMPFSA 440 Query: 294 GPRSCIGQNFAMIEAKAVIAMILQRFSFSL 205 G RSC+G+ A +E +LQ FSFS+ Sbjct: 441 GRRSCLGEPLARMELFLFFTTLLQAFSFSV 470
>C75A4_GENTR (Q96581) Flavonoid 3',5'-hydroxylase (EC 1.14.13.88) (F3'5'H)| (Cytochrome P450 75A4) Length = 516 Score = 56.6 bits (135), Expect = 4e-08 Identities = 30/93 (32%), Positives = 48/93 (51%), Gaps = 4/93 (4%) Frame = -3 Query: 471 LEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENG----VTRAGKHPNALLS 304 ++V G +PKGT + + I I RD VWG++ NEF P RF G + G H L+ Sbjct: 387 VDVNGYYIPKGTRLNVNIWAIGRDPSVWGDNPNEFDPERFLYGRNAKIDPRGNH-FELIP 445 Query: 303 FSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSL 205 F +G R C G ++ + ++ ++ F + L Sbjct: 446 FGAGRRICAGTRMGILLVEYILGTLVHSFDWKL 478
>CP6A1_MUSDO (P13527) Cytochrome P450 6A1 (EC 1.14.14.1) (CYPVIA1)| Length = 509 Score = 56.6 bits (135), Expect = 4e-08 Identities = 29/93 (31%), Positives = 53/93 (56%) Frame = -3 Query: 450 VPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPNALLSFSSGPRSCIGQ 271 +PKGT++ IP+ IH D E++ + EF P RF + + + L F GPR+CIG Sbjct: 395 LPKGTLVFIPVLGIHYDPELY-PNPEEFDPERFSPEMVKQRDSVD-WLGFGDGPRNCIGM 452 Query: 270 NFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDV 172 F ++++ +A++++ F F++ + PM + Sbjct: 453 RFGKMQSRLGLALVIRHFRFTVCSR-TDIPMQI 484
>CP1A2_RABIT (P00187) Cytochrome P450 1A2 (EC 1.14.14.1) (CYPIA2) (P450 isozyme| 4) (P450-PM4) (P450 LM4) Length = 515 Score = 56.6 bits (135), Expect = 4e-08 Identities = 43/117 (36%), Positives = 57/117 (48%), Gaps = 5/117 (4%) Frame = -3 Query: 474 DLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPNALLS--- 304 D + G +PK I I I+ D ++WG D EF+P RF +T G N LS Sbjct: 392 DTTLNGFHIPKECCIFINQWQINHDPQLWG-DPEEFRPERF---LTADGAAINKPLSEKV 447 Query: 303 --FSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITLRPKFGLPM 139 F G R CIG+ A E +A++LQR FS+ P P+D L P +GL M Sbjct: 448 TLFGLGKRRCIGETLARWEVFLFLAILLQRLEFSVPP---GVPVD---LTPIYGLTM 498
>CP2DA_MOUSE (P24456) Cytochrome P450 2D10 (EC 1.14.14.1) (CYPIID10)| (P450-16-alpha) (P450CB) (Testosterone 16-alpha hydroxylase) Length = 504 Score = 56.2 bits (134), Expect = 5e-08 Identities = 32/97 (32%), Positives = 52/97 (53%) Frame = -3 Query: 495 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPN 316 + R D+EV +PKG+++ ++++ +D+ VW E F P F + K P Sbjct: 377 LPRITSRDIEVQDFLIPKGSILIPNMSSVLKDETVW-EKPLRFHPEHFLDAQGHFVK-PE 434 Query: 315 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSL 205 A + FS+G RSC+G+ A +E +LQ FSFS+ Sbjct: 435 AFMPFSAGRRSCLGEPLARMELFLFFTCLLQHFSFSV 471
>CP19A_ICTPU (Q92111) Cytochrome P450 19A1 (EC 1.14.14.1) (Aromatase) (CYPXIX)| (Estrogen synthetase) (P-450AROM) Length = 524 Score = 56.2 bits (134), Expect = 5e-08 Identities = 35/92 (38%), Positives = 51/92 (55%) Frame = -3 Query: 489 RKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPNAL 310 R+A D + G +VP+GT I + + +HR E + + A +F F V P Sbjct: 395 RRALDDDVIEGFRVPRGTNIILNVGRMHRS-EFYPKPA-DFSLDNFNKPVPSRFFQP--- 449 Query: 309 LSFSSGPRSCIGQNFAMIEAKAVIAMILQRFS 214 F SGPRSC+G++ AM+ KAV+ M+L RFS Sbjct: 450 --FGSGPRSCVGKHIAMVMMKAVLLMVLSRFS 479
>CP19A_ORENI (P70091) Cytochrome P450 19A1 (EC 1.14.14.1) (Aromatase) (CYPXIX)| (Estrogen synthetase) (P-450AROM) Length = 522 Score = 55.8 bits (133), Expect = 6e-08 Identities = 32/92 (34%), Positives = 51/92 (55%) Frame = -3 Query: 489 RKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPNAL 310 R+A SD + G ++ KGT I + +HR + + N+F FEN V R P Sbjct: 384 RRALSDDIIEGYRISKGTNIILNTGRMHRTE--FFLKGNQFNLEHFENNVPR----PPTF 437 Query: 309 LSFSSGPRSCIGQNFAMIEAKAVIAMILQRFS 214 F SGPR+CIG++ AM+ K+++ +L ++S Sbjct: 438 QPFGSGPRACIGKHMAMVMMKSILVTLLSQYS 469
>C71AC_ARATH (O49340) Cytochrome P450 71A12 (EC 1.14.-.-)| Length = 497 Score = 55.8 bits (133), Expect = 6e-08 Identities = 33/96 (34%), Positives = 49/96 (51%), Gaps = 1/96 (1%) Frame = -3 Query: 495 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMR-FENGVTRAGKHP 319 + R D++V G + GT + I I RD +WG DA EFKP R ++ + GK Sbjct: 368 LPRLLSEDVKVKGYNIAAGTEVIINAWAIQRDPAIWGPDAEEFKPERHLDSTLDYHGKDL 427 Query: 318 NALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSF 211 N + F SG R C G N A+ + +A ++ RF + Sbjct: 428 N-FIPFGSGRRICPGINLALGLVEVTVANLVGRFDW 462
>CP6A8_DROME (Q27593) Cytochrome P450 6a8 (EC 1.14.-.-) (CYPVIA8)| Length = 506 Score = 55.8 bits (133), Expect = 6e-08 Identities = 30/85 (35%), Positives = 47/85 (55%) Frame = -3 Query: 450 VPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPNALLSFSSGPRSCIGQ 271 + G + IP + IH D ++ E EF+P RF + AG+ A L F GPR+CIG Sbjct: 397 IEAGQSVIIPSSAIHHDPSIYPEPF-EFRPERFSPEES-AGRPSVAWLPFGDGPRNCIGL 454 Query: 270 NFAMIEAKAVIAMILQRFSFSLSPK 196 F ++A+ +A++++ F FS K Sbjct: 455 RFGQMQARIGLALLIRNFKFSTCSK 479
>CP2R1_MOUSE (Q6VVW9) Cytochrome P450 2R1 (EC 1.14.14.-) (Vitamin D| 25-hydroxylase) Length = 501 Score = 55.5 bits (132), Expect = 8e-08 Identities = 34/113 (30%), Positives = 59/113 (52%), Gaps = 1/113 (0%) Frame = -3 Query: 474 DLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPNALLSFSS 295 D V G +PKGT + + ++H D++ W +D + F P RF + K AL+ FS Sbjct: 386 DAVVRGYSIPKGTTVITNLYSVHFDEKYW-KDPDMFYPERFLDSNGYFTKK-EALIPFSL 443 Query: 294 GPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVI-TLRPKFGLPM 139 G R C+G+ A +E +LQ+F ++H P +++ L+P+ G+ + Sbjct: 444 GRRHCLGEQLARMEMFLFFTSLLQQF-------HLHFPHELVPNLKPRLGMTL 489
>CP6D5_DROME (Q9VFP1) Probable cytochrome P450 6d5 (EC 1.14.-.-) (CYPVID5)| Length = 508 Score = 55.5 bits (132), Expect = 8e-08 Identities = 40/111 (36%), Positives = 54/111 (48%), Gaps = 5/111 (4%) Frame = -3 Query: 450 VPKGTVITIPIATIHRDKEVWGEDANEFKPMRF-ENG--VTRAGKHPNALLSFSSGPRSC 280 + KGT I I + +HRD+E + D +KP R+ ENG T+A A L F GPR C Sbjct: 400 IQKGTPIIISLIGMHRDEEYF-PDPLAYKPERYLENGKDYTQA-----AYLPFGEGPRMC 453 Query: 279 IGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDV--ITLRPKFGLPMIL 133 IG + K IA +L F + + V I L PK G+P+ L Sbjct: 454 IGARMGKVNVKIAIAKVLSNFDLEIRKEKCEIEFGVYGIPLMPKSGVPVRL 504
>C76C4_ARATH (O64635) Cytochrome P450 76C4 (EC 1.14.-.-)| Length = 511 Score = 55.5 bits (132), Expect = 8e-08 Identities = 35/108 (32%), Positives = 51/108 (47%) Frame = -3 Query: 495 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPN 316 + RKA SD+EV G VPK T + + + I RD VW E+ ++F+P RF Sbjct: 380 VPRKAESDVEVLGFMVPKDTQVLVNVWAIGRDPSVW-ENPSQFEPERFMGKDIDVKGRDY 438 Query: 315 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDV 172 L F G R C G A+ ++A +L F + L V +D+ Sbjct: 439 ELTPFGGGRRICPGLPLAVKTVSLMLASLLYSFDWKLPNGVVSEDLDM 486
>CP56_YEAST (P21595) Cytochrome P450-DIT2 (EC 1.14.14.-) (Cytochrome P450 56)| Length = 489 Score = 55.5 bits (132), Expect = 8e-08 Identities = 32/113 (28%), Positives = 57/113 (50%), Gaps = 11/113 (9%) Frame = -3 Query: 456 IKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVT------RAGKHPNALLSFSS 295 I +PKG + D + WG A++FKP R+ + + R K+ A+ F Sbjct: 371 IVIPKGVYVGYNNFGTSHDPKTWGTTADDFKPERWGSDIETIRKNWRMAKNRCAVTGFHG 430 Query: 294 GPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVH-----APMDVITLRPKF 151 G R+C+G+ A+ E + +A +L++F +SL P++ P+ + L+ KF Sbjct: 431 GRRACLGEKLALTEMRISLAEMLKQFRWSLDPEWEEKLTPAGPLCPLNLKLKF 483
>CP2J1_RABIT (P52786) Cytochrome P450 2J1 (EC 1.14.14.1) (CYPIIJ1) (P-450IB)| Length = 500 Score = 55.5 bits (132), Expect = 8e-08 Identities = 31/96 (32%), Positives = 48/96 (50%), Gaps = 1/96 (1%) Frame = -3 Query: 495 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRF-ENGVTRAGKHP 319 + R+ D + G +PKGTV+ + +H+D E W + F P F ENG K Sbjct: 378 VPREVTVDTTLAGYHLPKGTVVLTNLTALHKDPEEWA-TPDTFNPEHFLENG---QFKKK 433 Query: 318 NALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSF 211 A + FS G R+C+G+ A E ++Q+F+F Sbjct: 434 EAFIPFSIGKRACLGEQLAKSELFIFFTSLMQKFTF 469
>CP6A9_DROME (Q27594) Cytochrome P450 6a9 (EC 1.14.-.-) (CYPVIA9)| Length = 504 Score = 55.1 bits (131), Expect = 1e-07 Identities = 31/100 (31%), Positives = 53/100 (53%), Gaps = 3/100 (3%) Frame = -3 Query: 495 IQRKAGSDLEVGG---IKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGK 325 + R+ D EV G + KG + IP +HRD++++ + N F P F + + Sbjct: 377 LNRECLEDYEVPGHPKYVIKKGMPVLIPCGAMHRDEKLYA-NPNTFNPDNFSPERVKE-R 434 Query: 324 HPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSL 205 L F GPR+CIG F ++A++ +A+++ RF FS+ Sbjct: 435 DSVEWLPFGDGPRNCIGMRFGQMQARSGLALLINRFKFSV 474
>C71BC_ARATH (Q9ZU07) Cytochrome P450 71B12 (EC 1.14.-.-)| Length = 496 Score = 55.1 bits (131), Expect = 1e-07 Identities = 39/117 (33%), Positives = 53/117 (45%) Frame = -3 Query: 495 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPN 316 I R+A D+++GG +PK T I + I IHR+ VW +D F P RF + Sbjct: 366 IPREASKDVKIGGYNIPKKTWIHVNIWAIHRNPNVW-KDPEAFIPERFMDSQIDYKGLNF 424 Query: 315 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITLRPKFGL 145 LL F SG R C G M + +L RF + L A +D L +GL Sbjct: 425 ELLPFGSGRRICPGIGMGMALVHLTLINLLYRFDWKLPEGMKVADVD---LEESYGL 478
>C71AE_ARATH (P58045) Cytochrome P450 71A14 (EC 1.14.-.-)| Length = 497 Score = 55.1 bits (131), Expect = 1e-07 Identities = 29/101 (28%), Positives = 49/101 (48%) Frame = -3 Query: 495 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPN 316 + R+ D+++ G + GT + I I RD WG DA EF+P R + + Sbjct: 369 VPRELSEDIKLKGYDIAAGTQVIINAWAIQRDTMTWGIDAEEFRPERHLDSLVDFRGTNF 428 Query: 315 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKY 193 + F SG R C G FAM + +A ++ RF++ + ++ Sbjct: 429 EFIPFGSGRRICPGIGFAMALVEVTLANLVNRFNWRMEVQH 469
>CP1A1_CHACA (Q92039) Cytochrome P450 1A1 (EC 1.14.14.1) (CYPIA1)| Length = 521 Score = 55.1 bits (131), Expect = 1e-07 Identities = 35/117 (29%), Positives = 57/117 (48%), Gaps = 2/117 (1%) Frame = -3 Query: 483 AGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFE--NGVTRAGKHPNAL 310 + D + G +PK T + I I+RD E+W +D + F P RF NG + + Sbjct: 395 SAKDTSLNGYFIPKDTCVFINQWQINRDPELW-KDPSSFNPDRFLSCNGTEVNKQEGEKV 453 Query: 309 LSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITLRPKFGLPM 139 + F G R CIG+ A E +A+++QR F P +++ + P++GL M Sbjct: 454 MVFGMGKRRCIGEVIARNEVYRGLAILIQRLQFH------EMPGELLDMTPEYGLTM 504
>C71A8_MENPI (Q42716) Cytochrome P450 71A8 (EC 1.14.-.-)| Length = 502 Score = 55.1 bits (131), Expect = 1e-07 Identities = 32/97 (32%), Positives = 49/97 (50%) Frame = -3 Query: 495 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPN 316 + R A +D+EV G VP GT++ I I RD W ++ +F+P RF N Sbjct: 377 VPRVARNDVEVMGYDVPVGTMVMINAWAIGRDPTSW-DEPEKFRPERFLNSSVDFKGLDF 435 Query: 315 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSL 205 L+ F +G R C G F M + +A ++Q+F + L Sbjct: 436 ELIPFGAGRRGCPGTTFPMATLEFTLANLMQKFDWEL 472
>CP4G1_DROME (Q9V3S0) Cytochrome P450 4g1 (EC 1.14.-.-) (CYPIVG1)| Length = 556 Score = 55.1 bits (131), Expect = 1e-07 Identities = 30/99 (30%), Positives = 55/99 (55%), Gaps = 6/99 (6%) Frame = -3 Query: 495 IQRKAGSDLEV--GGIKVPKGTVITIPIATIHRDKEVWGE----DANEFKPMRFENGVTR 334 I R+ DL++ G VPKGT + + +HR +++ D + F P R N Sbjct: 426 IARRLDYDLKLASGPYTVPKGTTVIVLQYCVHRRPDIYPNPTKFDPDNFLPERMAN---- 481 Query: 333 AGKHPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRF 217 +H + + FS+GPRSC+G+ +AM++ K +++ I++ + Sbjct: 482 --RHYYSFIPFSAGPRSCVGRKYAMLKLKVLLSTIVRNY 518
>CP6D4_DROME (Q9VCW1) Probable cytochrome P450 6d4 (EC 1.14.-.-) (CYPVID4)| Length = 515 Score = 55.1 bits (131), Expect = 1e-07 Identities = 35/103 (33%), Positives = 47/103 (45%), Gaps = 1/103 (0%) Frame = -3 Query: 450 VPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPNALLSFSSGPRSCIGQ 271 +PKGT + I + IH D E + D + P RF +P A + F GPR CI Q Sbjct: 404 IPKGTPVVISLYGIHHDAEYF-PDPETYDPERFSE--ESRNYNPTAFMPFGEGPRICIAQ 460 Query: 270 NFAMIEAKAVIAMILQRFSFS-LSPKYVHAPMDVITLRPKFGL 145 I +K I ILQ F+ +S + I L PK G+ Sbjct: 461 RMGRINSKLAIIKILQNFNVEVMSRSEIEFENSGIALIPKHGV 503
>CP21A_PIG (P15540) Cytochrome P450 21 (EC 1.14.99.10) (Cytochrome P450 XXI)| (Steroid 21-hydroxylase) (21-OHase) (P450-C21) (P-450c21) Length = 492 Score = 54.7 bits (130), Expect = 1e-07 Identities = 32/95 (33%), Positives = 51/95 (53%) Frame = -3 Query: 498 AIQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHP 319 A+ +A + G +P+GTV+ + H D+ VW E +EF+P RF G +P Sbjct: 361 ALPHRATRPSSIFGYDIPEGTVVIPNLQGAHLDETVW-EQPHEFRPDRF----LAPGANP 415 Query: 318 NALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFS 214 +A L+F G R C+G+ A +E V+ +LQ F+ Sbjct: 416 SA-LAFGCGARVCLGEPLARLELFVVLVQLLQAFT 449
>CP192_CARAU (O73686) Cytochrome P450 19 type 2 (EC 1.14.14.1) (Ovarian| aromatase) (CYPXIXA2) (Estrogen synthetase) (P-450AROM) Length = 518 Score = 54.7 bits (130), Expect = 1e-07 Identities = 32/92 (34%), Positives = 49/92 (53%) Frame = -3 Query: 489 RKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPNAL 310 R+A D + G KV +GT I + + +HR + + NEF F+ V P Sbjct: 395 RRALDDDVIEGYKVKRGTNIILNVGRMHRSE--FFPKPNEFSLDNFQKNVPSRFFQP--- 449 Query: 309 LSFSSGPRSCIGQNFAMIEAKAVIAMILQRFS 214 F SGPRSC+G++ AM+ K+++ +L RFS Sbjct: 450 --FGSGPRSCVGKHMAMVMMKSILVTLLSRFS 479
>CP1A4_CHICK (P79760) Cytochrome P450 1A4 (EC 1.14.14.1) (CYPIA4) (P450 TCDDAHH)| Length = 530 Score = 54.7 bits (130), Expect = 1e-07 Identities = 37/120 (30%), Positives = 56/120 (46%), Gaps = 2/120 (1%) Frame = -3 Query: 474 DLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFEN--GVTRAGKHPNALLSF 301 D + G +PK T + I + D+++W +D FKP RF N G + + +L F Sbjct: 404 DTVLNGYYIPKDTCVFINQWQANHDEKIW-KDPPSFKPERFLNAAGTELSRTEADKVLIF 462 Query: 300 SSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITLRPKFGLPMILKSLE 121 G R CIG++ E + ILQ+ SL AP + + P++GL M K E Sbjct: 463 GLGKRRCIGESIGRWEVFLFLTTILQQLEISL------APGQRVDITPQYGLTMKYKQCE 516
>CP1A1_MESAU (Q00557) Cytochrome P450 1A1 (EC 1.14.14.1) (CYPIA1) (P-450MC)| Length = 524 Score = 54.7 bits (130), Expect = 1e-07 Identities = 34/116 (29%), Positives = 59/116 (50%), Gaps = 4/116 (3%) Frame = -3 Query: 474 DLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPNALLS--- 304 D + G +PKG + + I+ ++E+WG D N+F+P RF +T +G L Sbjct: 397 DTSLCGFYIPKGHCVFVNQWQINHNQELWG-DPNKFRPERF---LTSSGTLDKVLSGKVT 452 Query: 303 -FSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITLRPKFGLPM 139 F G R CIG+ +E +A++LQ+ F++SP + + + P +GL + Sbjct: 453 LFGLGKRKCIGETIGRLEVFLFLAILLQQIEFTVSPG------EKVDMTPIYGLTL 502
>CP17A_SQUAC (Q92113) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 509 Score = 54.7 bits (130), Expect = 1e-07 Identities = 34/105 (32%), Positives = 54/105 (51%), Gaps = 4/105 (3%) Frame = -3 Query: 495 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKH-- 322 I A +D +G +PKGT + I + IH D++ W ++ + F P RF + GK+ Sbjct: 374 IPHVALADSSIGDYTIPKGTRVIINLWAIHHDEKEW-KNPDAFDPGRF---LDEDGKYVC 429 Query: 321 --PNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKY 193 + L F +G R C+G+ A +E + ILQRF+ + P Y Sbjct: 430 SSSESYLPFGAGTRVCLGEMLARMELFLFTSWILQRFTVQVPPGY 474
>CP305_DROME (Q9VW43) Probable cytochrome P450 305a1 (EC 1.14.-.-) (CYPCCCVA1)| Length = 504 Score = 54.3 bits (129), Expect = 2e-07 Identities = 42/118 (35%), Positives = 57/118 (48%), Gaps = 6/118 (5%) Frame = -3 Query: 489 RKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGK--HPN 316 R+A ++GG +PK I I + ++H DKE W +D EF+P RF + AGK Sbjct: 383 RRALWATKLGGYDIPKNATILISLRSVHLDKEHW-KDPLEFRPERF---IDSAGKCFKDE 438 Query: 315 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSL----SPKYVHAPMDVITLRPK 154 + F G R C+G A + + I+Q FS L SP V P ITL PK Sbjct: 439 YFMPFGMGRRRCLGDALARACIFSFLVRIVQHFSVVLPAGESPSMVLLP--GITLTPK 494
>C76C2_ARATH (O64637) Cytochrome P450 76C2 (EC 1.14.-.-)| Length = 512 Score = 54.3 bits (129), Expect = 2e-07 Identities = 34/97 (35%), Positives = 48/97 (49%) Frame = -3 Query: 495 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPN 316 + RKA SD+EV G VPK T + + + I RD VW E+++ FKP RF Sbjct: 381 VPRKAESDVEVLGFMVPKDTQVFVNVWAIGRDPNVW-ENSSRFKPERFLGKDIDLRGRDY 439 Query: 315 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSL 205 L F +G R C G A+ ++A +L F + L Sbjct: 440 ELTPFGAGRRICPGLPLAVKTVPLMLASLLYSFDWKL 476
>C71AQ_ARATH (Q9STK7) Cytochrome P450 71A26 (EC 1.14.-.-)| Length = 489 Score = 54.3 bits (129), Expect = 2e-07 Identities = 29/98 (29%), Positives = 48/98 (48%) Frame = -3 Query: 495 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPN 316 + ++ D+ +G +P GT + I I R+ WG D EF+P R + Sbjct: 360 VPHESTQDVRLGDHHIPAGTQVLINAWAIGREAATWGPDVEEFRPERHLDSSVDYRGQAF 419 Query: 315 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLS 202 L+ F SG R C +FA++ + V+A ++ RF + LS Sbjct: 420 ELIPFGSGRRICPAISFAVVLNEVVLANLVHRFDWRLS 457
>C98A2_SOYBN (O48922) Cytochrome P450 98A2 (EC 1.14.-.-)| Length = 509 Score = 54.3 bits (129), Expect = 2e-07 Identities = 32/97 (32%), Positives = 53/97 (54%), Gaps = 1/97 (1%) Frame = -3 Query: 495 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRF-ENGVTRAGKHP 319 + +A ++++VGG +PKG+ + + + + RD VW +D EF+P RF E V G H Sbjct: 369 LPHRANANVKVGGYDIPKGSNVHVNVWAVARDPAVW-KDPLEFRPERFLEEDVDMKG-HD 426 Query: 318 NALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFS 208 LL F SG R C G + A +++ +L F ++ Sbjct: 427 FRLLPFGSGRRVCPGAQLGINLAASMLGHLLHHFCWT 463
>CP2DQ_MOUSE (Q8CIM7) Cytochrome P450 2D26 (EC 1.14.14.1) (CYPIID26)| Length = 500 Score = 54.3 bits (129), Expect = 2e-07 Identities = 31/90 (34%), Positives = 49/90 (54%) Frame = -3 Query: 474 DLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPNALLSFSS 295 D++ +PKGT + ++++ +D+ VW E F P F + KH A + FS+ Sbjct: 384 DIKFQDFFIPKGTTLIPNLSSVLKDETVW-EKPLRFYPEHFLDAQGHFVKH-EAFMPFSA 441 Query: 294 GPRSCIGQNFAMIEAKAVIAMILQRFSFSL 205 G RSC+G+ A +E +LQRFSFS+ Sbjct: 442 GRRSCLGEPLARMELFLFFTCLLQRFSFSV 471
>CP52V_CANAP (P43083) Cytochrome P450 52E1 (EC 1.14.14.-) (CYPLIIE1)| Length = 519 Score = 54.3 bits (129), Expect = 2e-07 Identities = 30/79 (37%), Positives = 41/79 (51%) Frame = -3 Query: 450 VPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPNALLSFSSGPRSCIGQ 271 VPKG + ++ R ++WG DA F+P R+ N A + F+ GPR C+GQ Sbjct: 406 VPKGQNVFYSTYSMQRRTDIWGPDATTFRPDRW-NEPREALASGWDYIPFNGGPRICLGQ 464 Query: 270 NFAMIEAKAVIAMILQRFS 214 FA+ EA I I Q FS Sbjct: 465 QFALTEASYTIVRICQEFS 483
>CP310_DROME (Q9VJ71) Probable cytochrome P450 310a1 (EC 1.14.-.-) (CYPCCCXA1)| Length = 492 Score = 53.9 bits (128), Expect = 2e-07 Identities = 35/122 (28%), Positives = 55/122 (45%), Gaps = 11/122 (9%) Frame = -3 Query: 450 VPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGK-----HPNALLSFSSGPR 286 + +G + +P+ +HRD++ + E ++KP+RF G+ N + F G Sbjct: 368 IDEGKTLMVPLLAMHRDEKYFSEPM-KYKPLRFLQTANDVGQCEDKTKSNVFIGFGIGGS 426 Query: 285 SCIGQNFAMIEAKAVIAMILQRFSFSLSPKYV------HAPMDVITLRPKFGLPMILKSL 124 C+GQNFA + K + +LQ F L V H P I K GL + LK Sbjct: 427 QCVGQNFAKLVIKVALIKLLQNFHLELDANQVKTLKVSHRPAPFI--HTKDGLKVKLKRR 484 Query: 123 EM 118 E+ Sbjct: 485 EI 486
>C4D14_DROME (O46051) Probable cytochrome P450 4d14 (EC 1.14.-.-) (CYPIVD14)| Length = 507 Score = 53.9 bits (128), Expect = 2e-07 Identities = 42/123 (34%), Positives = 63/123 (51%), Gaps = 1/123 (0%) Frame = -3 Query: 495 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGK-HP 319 I R D + G +P + + I I RD + + D +F P RF + R G+ P Sbjct: 385 IGRYISQDTVLDGKLIPADSNVIILIYHAQRDPDYF-PDPEKFIPDRFS--MERKGEISP 441 Query: 318 NALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITLRPKFGLPM 139 A FS+GPR+CIGQ FAM+E K+ I+ +++ F + V ++VI LR G+ Sbjct: 442 FAYTPFSAGPRNCIGQKFAMLEMKSTISKMVRHFELLPLGEEVQPVLNVI-LRSTTGINC 500 Query: 138 ILK 130 LK Sbjct: 501 GLK 503
>C71BD_ARATH (P58050) Cytochrome P450 71B13 (EC 1.14.-.-)| Length = 496 Score = 53.9 bits (128), Expect = 2e-07 Identities = 35/96 (36%), Positives = 49/96 (51%), Gaps = 1/96 (1%) Frame = -3 Query: 489 RKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRF-ENGVTRAGKHPNA 313 R+A D+++GG +PK T I + I IHR+ VW +D F P RF +N + G + Sbjct: 368 REASKDVKIGGYNIPKKTWIHVNIWAIHRNPNVW-KDPEAFIPERFMDNQIDYKGLN-FE 425 Query: 312 LLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSL 205 LL F SG R C G M + +L RF + L Sbjct: 426 LLPFGSGRRICPGIGMGMALIHLTLINLLYRFDWKL 461
>C71BB_ARATH (P58049) Cytochrome P450 71B11 (EC 1.14.-.-)| Length = 496 Score = 53.9 bits (128), Expect = 2e-07 Identities = 35/98 (35%), Positives = 49/98 (50%), Gaps = 1/98 (1%) Frame = -3 Query: 495 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRF-ENGVTRAGKHP 319 I R+A D+++GG +PK T I + I IHR+ VW +D F P RF +N + G + Sbjct: 366 IPREASKDVKIGGYDIPKKTWIHVNIWAIHRNPNVW-KDPEAFIPERFMDNQIDYKGLN- 423 Query: 318 NALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSL 205 L F SG R C G M + +L RF + L Sbjct: 424 FEFLPFGSGRRMCPGIGMGMALVHLTLINLLYRFDWKL 461
>CP6B7_HELAM (O61387) Cytochrome P450 6B7 (EC 1.14.14.1) (CYPVIB7)| Length = 504 Score = 53.9 bits (128), Expect = 2e-07 Identities = 38/123 (30%), Positives = 61/123 (49%), Gaps = 6/123 (4%) Frame = -3 Query: 495 IQRKAGSDLEVGG--IKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGK- 325 +QRKA D ++ G + + K T++ I IH D + + ++ +F P RF+ GK Sbjct: 374 LQRKATRDYQIPGTDVVIEKDTMVLISPRGIHYDPKYY-DNPKQFNPDRFD--AEEVGKR 430 Query: 324 HPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLS---PKYVHAPMDVITLRPK 154 HP A L F G R+CIG F +++ I IL +F S + + +T+ PK Sbjct: 431 HPCAYLPFGLGQRNCIGMRFGRLQSLLCITKILSKFRIEPSKNTDRNLQVEPRRVTIGPK 490 Query: 153 FGL 145 G+ Sbjct: 491 GGI 493
>CP392_DROME (P82713) Probable cytochrome P450 309a2 (EC 1.14.-.-) (CYPCCCIXA2)| Length = 538 Score = 53.9 bits (128), Expect = 2e-07 Identities = 31/84 (36%), Positives = 40/84 (47%) Frame = -3 Query: 468 EVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPNALLSFSSGP 289 E + V G I IP H DK+ + E FKP RF+NG + L FS GP Sbjct: 422 ESKSLDVEVGMTIMIPNYQFHHDKQYFPEP-EAFKPERFDNGAYQELMRKGIFLPFSDGP 480 Query: 288 RSCIGQNFAMIEAKAVIAMILQRF 217 R C+G AM+ K+ + IL F Sbjct: 481 RICMGVPLAMLTLKSALVHILSNF 504
>C71AR_ARATH (O65438) Cytochrome P450 71A27 (EC 1.14.-.-)| Length = 499 Score = 53.9 bits (128), Expect = 2e-07 Identities = 29/98 (29%), Positives = 53/98 (54%), Gaps = 3/98 (3%) Frame = -3 Query: 489 RKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMR---FENGVTRAGKHP 319 R D+++ G + GT + I + R+ +WG DANE++P R +E G R Sbjct: 369 RLPSEDVQLKGYDISAGTHVIINAWALQRNPAIWGLDANEYRPERHFWYEFGFQRT---D 425 Query: 318 NALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSL 205 + + F +G R C G F+++ +K +A +++RF++ L Sbjct: 426 SKFVPFGAGRRLCPGIGFSLVLSKLALANLVKRFNWRL 463
>C71AO_ARATH (Q9STK9) Cytochrome P450 71A24 (EC 1.14.-.-)| Length = 486 Score = 53.9 bits (128), Expect = 2e-07 Identities = 29/108 (26%), Positives = 52/108 (48%) Frame = -3 Query: 495 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPN 316 + ++ D+++ +P GT + I I R+ WG DA EF+P R N Sbjct: 360 VPHESTHDVKLRDYHIPAGTHVMINAWAIGREAATWGPDAEEFRPERHLNSYVDYRGQDT 419 Query: 315 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDV 172 L+ F +G R C +FA++ + V+A ++ +F ++L + DV Sbjct: 420 ELVPFGAGRRICPAISFAVVLDEVVLANLVHQFDWTLPEESTEYQTDV 467
>C75A7_EUSGR (O04790) Flavonoid 3',5'-hydroxylase (EC 1.14.13.88) (F3'5'H)| (Cytochrome P450 75A7) Length = 510 Score = 53.5 bits (127), Expect = 3e-07 Identities = 33/110 (30%), Positives = 52/110 (47%), Gaps = 3/110 (2%) Frame = -3 Query: 495 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRF---ENGVTRAGK 325 + R A EV G +PKGT +++ I I RD VW E+ NEF P RF +N Sbjct: 374 LPRIASQACEVNGHYIPKGTRLSVNIWAIGRDPSVW-ENPNEFNPDRFLERKNAKIDPRG 432 Query: 324 HPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMD 175 + L+ F +G R C G ++ + ++ ++ F + L + MD Sbjct: 433 NDFELIPFGAGRRICAGTRLGILLVEYILGTLVHSFVWELPSSVIELNMD 482
>C71AJ_ARATH (Q9T0K0) Cytochrome P450 71A19 (EC 1.14.-.-)| Length = 490 Score = 53.5 bits (127), Expect = 3e-07 Identities = 29/97 (29%), Positives = 44/97 (45%) Frame = -3 Query: 495 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPN 316 + R D+ + G +P GT + I I RD WG DA EF+P R + + Sbjct: 362 VPRVFSEDVTLKGYNIPAGTQVIINAWAIQRDTTTWGIDAEEFRPERHLDSILDFQGQDF 421 Query: 315 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSL 205 + F SG R C G F +A I++RF++ + Sbjct: 422 KFIPFGSGKRICPGIGFTSALIGVTLANIVKRFNWRM 458
>CP391_DROME (Q9VQD2) Probable cytochrome P450 309a1 (EC 1.14.-.-) (CYPCCCIXA1)| Length = 529 Score = 53.5 bits (127), Expect = 3e-07 Identities = 25/75 (33%), Positives = 35/75 (46%) Frame = -3 Query: 441 GTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPNALLSFSSGPRSCIGQNFA 262 G + +P H D +++ E A+EF+P RFENG L F GPR C+G Sbjct: 423 GVTVMVPAYQYHHDNDIYPE-ASEFRPDRFENGAASVLTKRGCFLPFGDGPRICLGMRVG 481 Query: 261 MIEAKAVIAMILQRF 217 + K I IL + Sbjct: 482 QLSVKTAIVHILSNY 496
>CP137_MYCTU (O69653) Putative cytochrome P450 137 (EC 1.14.-.-)| Length = 476 Score = 53.1 bits (126), Expect = 4e-07 Identities = 34/96 (35%), Positives = 50/96 (52%), Gaps = 2/96 (2%) Frame = -3 Query: 489 RKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPN-- 316 R A L +GG +V GT I + I I+R EV+ E +EF+P RF G P Sbjct: 358 RVAAQPLTIGGYRVEAGTRIVVHIIAINRSAEVY-EHPHEFRPERF------LGTRPQTY 410 Query: 315 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFS 208 A + F G + C+G NF+M E V+ ++L+ F+ Sbjct: 411 AWVPFGGGVKRCLGANFSMRELITVLHVLLREGEFT 446
>C75A5_EUSGR (Q96418) Flavonoid 3',5'-hydroxylase (EC 1.14.13.88) (F3'5'H)| (Cytochrome P450 75A5) Length = 510 Score = 53.1 bits (126), Expect = 4e-07 Identities = 32/110 (29%), Positives = 52/110 (47%), Gaps = 3/110 (2%) Frame = -3 Query: 495 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRF---ENGVTRAGK 325 + R A EV G +PKGT +++ I I RD +W E+ NEF P RF +N Sbjct: 374 LPRIASQACEVNGHYIPKGTRLSVNIWAIGRDPSLW-ENPNEFNPDRFLERKNAKIDPRG 432 Query: 324 HPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMD 175 + L+ F +G R C G ++ + ++ ++ F + L + MD Sbjct: 433 NDFELIPFGAGRRICAGTRLGILLVEYILGTLVHSFDWELPSSVIELNMD 482
>C97B2_SOYBN (O48921) Cytochrome P450 97B2 (EC 1.14.-.-)| Length = 576 Score = 53.1 bits (126), Expect = 4e-07 Identities = 36/125 (28%), Positives = 55/125 (44%), Gaps = 28/125 (22%) Frame = -3 Query: 495 IQRKAGSDLEVGGIK-------VPKGTVITIPIATIHRDKEVWGEDANEFKPMRF----- 352 I+R SD+ GG K +P GT + I + +HR W + ++F+P RF Sbjct: 421 IRRSLKSDVLPGGHKGEKDGYAIPAGTDVFISVYNLHRSPYFW-DRPDDFEPERFLVQNK 479 Query: 351 ----------ENGVTRAGKHPN------ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQR 220 + + +PN A L F GPR C+G FA++E+ + M+LQ Sbjct: 480 NEEIEGWAGLDPSRSPGALYPNEVISDFAFLPFGGGPRKCVGDQFALMESTVALTMLLQN 539 Query: 219 FSFSL 205 F L Sbjct: 540 FDVEL 544
>CP2J5_MOUSE (O54749) Cytochrome P450 2J5 (EC 1.14.14.1) (CYPIIJ5) (Arachidonic| acid epoxygenase) Length = 501 Score = 53.1 bits (126), Expect = 4e-07 Identities = 31/94 (32%), Positives = 47/94 (50%), Gaps = 1/94 (1%) Frame = -3 Query: 489 RKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRF-ENGVTRAGKHPNA 313 R+ D + G +PKGT+I + +HRD + W F P F ENG K + Sbjct: 381 REVTVDTKFNGFHLPKGTMILTNLTALHRDPKEWATP-EVFNPEHFLENGQF---KKRES 436 Query: 312 LLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSF 211 L FS G R+C+G+ A E + ++Q+F+F Sbjct: 437 FLPFSMGKRACLGEQLAKSELFIFFSALMQKFTF 470
>C94A1_VICSA (O81117) Cytochrome P450 94A1 (EC 1.14.-.-) (P450-dependent fatty| acid omega-hydroxylase) Length = 514 Score = 53.1 bits (126), Expect = 4e-07 Identities = 30/92 (32%), Positives = 50/92 (54%), Gaps = 6/92 (6%) Frame = -3 Query: 474 DLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRF-----ENGV-TRAGKHPNA 313 D+ G V KGT++T + + R K +WG+D EF+P R+ NG G+ + Sbjct: 388 DVLPDGWVVKKGTIVTYHVYAMGRMKSLWGDDWAEFRPERWLEKDEVNGKWVFVGRDSYS 447 Query: 312 LLSFSSGPRSCIGQNFAMIEAKAVIAMILQRF 217 F +GPR C+G+ A ++ K ++A I+ +F Sbjct: 448 YPVFQAGPRVCLGKEMAFMQMKRIVAGIVGKF 479
>CP6B6_HELAM (Q95031) Cytochrome P450 6B6 (EC 1.14.14.1) (CYPVIB6)| Length = 504 Score = 53.1 bits (126), Expect = 4e-07 Identities = 33/96 (34%), Positives = 51/96 (53%), Gaps = 3/96 (3%) Frame = -3 Query: 495 IQRKAGSDLEVGG--IKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGK- 325 +QRKA D ++ G + + K T++ I IH D + + ++ +F P RF+ GK Sbjct: 374 LQRKATRDYKIPGTDVVIEKDTIVLISPRGIHYDPKYY-DNPKQFNPDRFD--AEEVGKR 430 Query: 324 HPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRF 217 HP A L F G R+CIG F +++ I IL +F Sbjct: 431 HPCAYLPFGLGQRNCIGMRFGRLQSLLCITKILSKF 466
>C6A21_DROME (Q9V774) Probable cytochrome P450 6a21 (EC 1.14.-.-) (CYPVIA21)| Length = 504 Score = 53.1 bits (126), Expect = 4e-07 Identities = 31/103 (30%), Positives = 53/103 (51%), Gaps = 3/103 (2%) Frame = -3 Query: 495 IQRKAGSDLEVGG---IKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGK 325 + R+ D EV G + KG + IP +HRD++++ + N F P F + + Sbjct: 377 LNRECLEDYEVPGHPKYVIKKGMPVLIPCGAMHRDEKLYA-NPNTFNPDNFSPERVKE-R 434 Query: 324 HPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPK 196 L F GPR+CIG F ++A+ +A++++ F FS+ K Sbjct: 435 DSVEWLPFGDGPRNCIGMRFGQMQARIGLALLIKDFKFSVCEK 477
>C71AK_ARATH (Q9T0K2) Cytochrome P450 71A20 (EC 1.14.-.-)| Length = 495 Score = 53.1 bits (126), Expect = 4e-07 Identities = 29/97 (29%), Positives = 44/97 (45%) Frame = -3 Query: 495 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPN 316 + R D+++ G +P GT + + I RD WG DA EFKP R + Sbjct: 367 VPRVLSEDVKLKGYNIPAGTQVIVNAWAIQRDTTTWGTDAEEFKPERHLDTNLDFQGQDF 426 Query: 315 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSL 205 + F SG R C G F +A I++RF++ + Sbjct: 427 KFIPFGSGKRICPGIGFTSALIGVTLANIVKRFNWRM 463
>CP19A_ANGJA (Q6QHT9) Cytochrome P450 19A1 (EC 1.14.14.1) (Aromatase) (CYPXIX)| (Estrogen synthetase) (P-450AROM) Length = 511 Score = 53.1 bits (126), Expect = 4e-07 Identities = 32/92 (34%), Positives = 50/92 (54%) Frame = -3 Query: 489 RKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPNAL 310 RK+ D + G KV KGT I + + +H+ + + NEF FE V P Sbjct: 388 RKSLEDDVIEGYKVFKGTNIILNVGRMHKCE--FFSKPNEFSLENFEKTVPNRFFQP--- 442 Query: 309 LSFSSGPRSCIGQNFAMIEAKAVIAMILQRFS 214 F SGPRSC+G++ +M+ KA++A +L R++ Sbjct: 443 --FGSGPRSCVGKHISMVMMKAILATLLSRYT 472
>CP17A_FELCA (Q9GMC8) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 508 Score = 53.1 bits (126), Expect = 4e-07 Identities = 32/98 (32%), Positives = 51/98 (52%), Gaps = 1/98 (1%) Frame = -3 Query: 495 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPN 316 I KA D +G V KGT + I + +H +++ W ++F P RF + P+ Sbjct: 371 IPHKAIMDSSIGEFAVDKGTNVIINLWALHHNEKEWYRP-DQFMPERFLDPTRSQLISPS 429 Query: 315 -ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSL 205 + L F +GPRSC+G++ A E +A +LQRF + Sbjct: 430 LSYLPFGAGPRSCLGESLARQEVFLFMAWLLQRFDLEV 467
>CP17A_CHICK (P12394) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 508 Score = 53.1 bits (126), Expect = 4e-07 Identities = 35/117 (29%), Positives = 60/117 (51%), Gaps = 6/117 (5%) Frame = -3 Query: 477 SDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPNA----L 310 +D +G +PKG + I + ++H D++ W + EF P RF + G+H ++ Sbjct: 380 ADTSIGEYSIPKGARVVINLWSVHHDEKEW-DKPEEFNPGRF---LDEQGQHIHSPSPSY 435 Query: 309 LSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMD--VITLRPKFGL 145 L F +G R C+G+ A +E +A +LQRF+ + P D + +L KFG+ Sbjct: 436 LPFGAGIRVCLGEVLAKMELFLFLAWVLQRFT-------LECPQDQPLPSLEGKFGV 485
>CP2J2_HUMAN (P51589) Cytochrome P450 2J2 (EC 1.14.14.1) (CYPIIJ2) (Arachidonic| acid epoxygenase) Length = 502 Score = 53.1 bits (126), Expect = 4e-07 Identities = 31/96 (32%), Positives = 47/96 (48%), Gaps = 1/96 (1%) Frame = -3 Query: 495 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRF-ENGVTRAGKHP 319 + R+ D + G +PKGT+I + +HRD W + F P F ENG K Sbjct: 380 VPREVTVDTTLAGYHLPKGTMILTNLTALHRDPTEWATP-DTFNPDHFLENGQF---KKR 435 Query: 318 NALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSF 211 A + FS G R+C+G+ A E ++Q+F+F Sbjct: 436 EAFMPFSIGKRACLGEQLARTELFIFFTSLMQKFTF 471
>CP6D1_MUSDO (Q27698) Cytochrome P450 6d1 (EC 1.14.-.-) (CYPVID1) (Pyrethroid| resistance cytochrome P450) (Cytochrome P450 Ipr) Length = 516 Score = 53.1 bits (126), Expect = 4e-07 Identities = 32/102 (31%), Positives = 50/102 (49%), Gaps = 2/102 (1%) Frame = -3 Query: 495 IQRKAGSDLEVGGIK--VPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKH 322 + RK D +V K +PK T I I + IHRD + + + +++P RF + Sbjct: 391 LNRKCTQDFQVPDTKLTIPKETGIIISLLGIHRDPQYFPQP-EDYRPERFAD--ESKDYD 447 Query: 321 PNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPK 196 P A + F GPR CI Q ++ +K +A IL F+ P+ Sbjct: 448 PAAYMPFGEGPRHCIAQRMGVMNSKVALAKILANFNIQPMPR 489
>CP318_DROME (Q9VYQ5) Probable cytochrome P450 318a1 (EC 1.14.-.-)| (CYPCCCXVIIIA1) Length = 536 Score = 53.1 bits (126), Expect = 4e-07 Identities = 32/130 (24%), Positives = 58/130 (44%), Gaps = 31/130 (23%) Frame = -3 Query: 450 VPKGTVITIPIATIHRDKEVWGEDANEFKPMRF------------------ENGVTRAGK 325 VP+ +++ + + RD+ WG +A +F P RF E R + Sbjct: 403 VPQNSIVVLDTFNMQRDERWWGANARQFDPQRFLDQEEEQLSKGHNDSGSGEKRRQRDRR 462 Query: 324 HPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSF-------------SLSPKYVHA 184 H + L FS+G RSCIG+ + + K + ++ F F ++S K+ +A Sbjct: 463 HSYSFLPFSNGLRSCIGRRYGLFIMKVFLVKLITNFDFQSDFELEKLQFVENISLKFKNA 522 Query: 183 PMDVITLRPK 154 ++T++PK Sbjct: 523 DDILLTIQPK 532
>C81F1_ARATH (O65790) Cytochrome P450 81F1 (EC 1.14.-.-)| Length = 500 Score = 53.1 bits (126), Expect = 4e-07 Identities = 27/95 (28%), Positives = 48/95 (50%) Frame = -3 Query: 495 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPN 316 I R D+++GG VP+ T++ + IHRD E+W E+ +F P R+ +G + + Sbjct: 369 IPRSPTDDMKIGGYDVPRDTIVMVNAWAIHRDPEIW-EEPEKFNPDRYNDG-CGSDYYVY 426 Query: 315 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSF 211 L+ F +G R+C G + ++Q F + Sbjct: 427 KLMPFGNGRRTCPGAGLGQRIVTLALGSLIQCFEW 461
>CP17A_ORYLA (P70085) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 517 Score = 53.1 bits (126), Expect = 4e-07 Identities = 37/118 (31%), Positives = 61/118 (51%), Gaps = 1/118 (0%) Frame = -3 Query: 495 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPN 316 I A SD +G V KGT + I + ++H D++ W + + F P RF + + P+ Sbjct: 380 IPHVALSDTSLGDFTVRKGTRVVINLWSLHHDEKEW-TNPDLFNPGRFLSADGSSLTLPS 438 Query: 315 A-LLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITLRPKFGL 145 + L F +G R C+G+ A +E ++ ILQRF+ S+ P + +L KFG+ Sbjct: 439 SSYLPFGAGLRVCLGEALAKMELFLFLSWILQRFTLSVPPS-----QSLPSLEGKFGV 491
>CP9H1_DROME (Q9V6H1) Probable cytochrome P450 9h1 (EC 1.14.-.-) (CYPIXH1)| Length = 518 Score = 52.8 bits (125), Expect = 5e-07 Identities = 28/76 (36%), Positives = 42/76 (55%) Frame = -3 Query: 444 KGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPNALLSFSSGPRSCIGQNF 265 KG V+ IPI ++H D E + ED F P RF +G + + F GPR+CIG Sbjct: 412 KGDVLQIPIFSLHHDPENF-EDPEFFNPERFADGHALESR---VYMPFGVGPRNCIGNRM 467 Query: 264 AMIEAKAVIAMILQRF 217 A++E K+++ +L F Sbjct: 468 ALMELKSIVYQLLLNF 483
>CP1A2_HUMAN (P05177) Cytochrome P450 1A2 (EC 1.14.14.1) (CYPIA2) (P450-P3)| (P(3)450) (P450 4) Length = 514 Score = 52.8 bits (125), Expect = 5e-07 Identities = 35/114 (30%), Positives = 54/114 (47%), Gaps = 2/114 (1%) Frame = -3 Query: 474 DLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHP--NALLSF 301 D + G +PK + + ++ D E+W ED +EF+P RF A P ++ F Sbjct: 392 DTTLNGFYIPKKCCVFVNQWQVNHDPELW-EDPSEFRPERFLTADGTAINKPLSEKMMLF 450 Query: 300 SSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITLRPKFGLPM 139 G R CIG+ A E +A++LQ+ FS+ P + L P +GL M Sbjct: 451 GMGKRRCIGEVLAKWEIFLFLAILLQQLEFSVPPGV------KVDLTPIYGLTM 498
>CP9E2_BLAGE (Q964T2) Cytochrome P450 9e2 (EC 1.14.-.-) (CYPIXE2)| Length = 533 Score = 52.8 bits (125), Expect = 5e-07 Identities = 29/82 (35%), Positives = 44/82 (53%) Frame = -3 Query: 441 GTVITIPIATIHRDKEVWGEDANEFKPMRFENGVTRAGKHPNALLSFSSGPRSCIGQNFA 262 G + IPI IH D + + + +F P RF + + P L F SGPR+CIG FA Sbjct: 424 GDAVWIPIYAIHHDPKYY-PNPEKFDPERFSDE-NKDNIKPFTYLPFGSGPRNCIGNRFA 481 Query: 261 MIEAKAVIAMILQRFSFSLSPK 196 ++E+K + +L RF+ + K Sbjct: 482 LMESKIALVHLLCRFNLKVVSK 503 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 79,534,598 Number of Sequences: 219361 Number of extensions: 1728838 Number of successful extensions: 5115 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 4635 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 4802 length of database: 80,573,946 effective HSP length: 104 effective length of database: 57,760,402 effective search space used: 3638905326 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
