>NU214_HUMAN (P35658) Nuclear pore complex protein Nup214 (Nucleoporin Nup214)|
            (214 kDa nucleoporin) (CAN protein)
          Length = 2090

 Score = 33.5 bits (75), Expect = 0.34
 Identities = 22/64 (34%), Positives = 30/64 (46%), Gaps = 1/64 (1%)
 Frame = -2

Query: 405  AAGSGGVAGQGHAVEDVGQTIGFGSQPLVDNSPYDSGAPKHGCSLLRIGV-ALGVSSAIV 229
            ++G G VA QG       +T GFG+ P+  + P   G+P  G      GV A G + A  
Sbjct: 1948 SSGGGSVASQGFGFSSPNKTGGFGAAPVFGSPPTFGGSPGFG------GVPAFGSAPAFT 2001

Query: 228  MALG 217
              LG
Sbjct: 2002 SPLG 2005

>HORN_HUMAN (Q86YZ3) Hornerin|
          Length = 2850

 Score = 31.2 bits (69), Expect = 1.7
 Identities = 22/73 (30%), Positives = 31/73 (42%), Gaps = 1/73 (1%)
 Frame = -2

Query: 495 GHGSSNLPFGQEPESNGN-TGVAQPALPLPEAAGSGGVAGQGHAVEDVGQTIGFGSQPLV 319
           GHG      GQ P S  + TG  + +   P  +GSG  +G GH       + G+      
Sbjct: 425 GHGQRGSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQHG-- 482

Query: 318 DNSPYDSGAPKHG 280
             S + SG  +HG
Sbjct: 483 SGSGHSSGHGQHG 495



 Score = 30.0 bits (66), Expect = 3.7
 Identities = 24/80 (30%), Positives = 34/80 (42%), Gaps = 3/80 (3%)
 Frame = -2

Query: 504  EPVGHGSSNLPFGQEPE-SNGN--TGVAQPALPLPEAAGSGGVAGQGHAVEDVGQTIGFG 334
            + +GHG      GQ P  S G   +G  Q +   P  +GSG  + +G      G + G G
Sbjct: 2402 QSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGLG 2461

Query: 333  SQPLVDNSPYDSGAPKHGCS 274
             +     S   SG  +HG S
Sbjct: 2462 HRE--SRSGQSSGYGQHGSS 2479



 Score = 29.3 bits (64), Expect = 6.4
 Identities = 24/80 (30%), Positives = 34/80 (42%), Gaps = 3/80 (3%)
 Frame = -2

Query: 504  EPVGHGSSNLPFGQEPE-SNGN--TGVAQPALPLPEAAGSGGVAGQGHAVEDVGQTIGFG 334
            + +GHG      GQ P  S G   +G  Q +   P  +GSG  + +G      G + G G
Sbjct: 1932 QSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYGSGSGWSSSRGPYESGSGHSSGLG 1991

Query: 333  SQPLVDNSPYDSGAPKHGCS 274
             +     S   SG  +HG S
Sbjct: 1992 HRE--SRSGQSSGYGQHGSS 2009



 Score = 28.9 bits (63), Expect = 8.3
 Identities = 21/72 (29%), Positives = 31/72 (43%)
 Frame = -2

Query: 495  GHGSSNLPFGQEPESNGNTGVAQPALPLPEAAGSGGVAGQGHAVEDVGQTIGFGSQPLVD 316
            G  SS  P+G     + + G        P  +GSG  +G GH     GQ+ G+G      
Sbjct: 2429 GQSSSYSPYGSGSGWSSSRG--------PYESGSGHSSGLGHRESRSGQSSGYGQHG--S 2478

Query: 315  NSPYDSGAPKHG 280
            +S + S   +HG
Sbjct: 2479 SSGHSSTHGQHG 2490



 Score = 28.9 bits (63), Expect = 8.3
 Identities = 22/76 (28%), Positives = 28/76 (36%), Gaps = 1/76 (1%)
 Frame = -2

Query: 504 EPVGHGSSNLPFGQEPES-NGNTGVAQPALPLPEAAGSGGVAGQGHAVEDVGQTIGFGSQ 328
           + +GHG       Q P      +G    +      +GS     +GH     GQT GFG  
Sbjct: 292 QSLGHGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQH 351

Query: 327 PLVDNSPYDSGAPKHG 280
                S   SG  KHG
Sbjct: 352 E--SGSGQSSGYSKHG 365

>IF2_STRAW (Q82K53) Translation initiation factor IF-2|
          Length = 1046

 Score = 30.8 bits (68), Expect = 2.2
 Identities = 25/73 (34%), Positives = 29/73 (39%)
 Frame = -2

Query: 507 AEPVGHGSSNLPFGQEPESNGNTGVAQPALPLPEAAGSGGVAGQGHAVEDVGQTIGFGSQ 328
           A P G    N PF     S G+TG+A+P  P P  A   G AG        G     G Q
Sbjct: 207 ARPAGPRPGNNPF----TSGGSTGMARPQAPRPGGAPRPGGAGAPGGPRPQGA----GGQ 258

Query: 327 PLVDNSPYDSGAP 289
              D +P   G P
Sbjct: 259 ---DRAPRPQGGP 268

>MBN_DROME (P52302) Protein lethal(3)malignant blood neoplasm 1 (Mbn(83))|
          Length = 653

 Score = 30.8 bits (68), Expect = 2.2
 Identities = 28/85 (32%), Positives = 34/85 (40%)
 Frame = -2

Query: 486 SSNLPFGQEPESNGNTGVAQPALPLPEAAGSGGVAGQGHAVEDVGQTIGFGSQPLVDNSP 307
           ++N P G  P SNG    A  A   P+A GSGG+ G G          G GS   +    
Sbjct: 414 TANTPTGNVP-SNGGGIAAGKAPGNPQAGGSGGIIGAGAPGGRKVSAGGIGSGSAI---- 468

Query: 306 YDSGAPKHGCSLLRIGVALGVSSAI 232
              G    G      G A+G  SAI
Sbjct: 469 ---GGVSGGSKASGNGGAIGSGSAI 490

>IF2_STRCO (Q8CJQ8) Translation initiation factor IF-2|
          Length = 1033

 Score = 30.4 bits (67), Expect = 2.9
 Identities = 25/78 (32%), Positives = 32/78 (41%), Gaps = 6/78 (7%)
 Frame = -2

Query: 501 PVGHGSSNLPFGQEPESNGNTGVAQPALPLPEA----AGSGGVAGQGHAVEDVGQTIGFG 334
           P G    N PF     S GN G+A+P+ P P+      G GG  G G   +  G   G G
Sbjct: 213 PGGPRPGNNPF----TSGGNAGMARPSAPRPQGGPRPGGPGGAPGGGPRPQGPGGQ-GGG 267

Query: 333 SQPLV--DNSPYDSGAPK 286
            +P     N P     P+
Sbjct: 268 PRPQAPGGNRPSPGSMPR 285

>NFKB2_HUMAN (Q00653) Nuclear factor NF-kappa-B p100 subunit (DNA-binding factor|
           KBF2) (H2TF1) (Lymphocyte translocation chromosome 10)
           (Oncogene Lyt-10) (Lyt10) [Contains: Nuclear factor
           NF-kappa-B p52 subunit]
          Length = 899

 Score = 30.0 bits (66), Expect = 3.7
 Identities = 19/41 (46%), Positives = 22/41 (53%)
 Frame = -2

Query: 399 GSGGVAGQGHAVEDVGQTIGFGSQPLVDNSPYDSGAPKHGC 277
           GSGG AG G+     G ++GF    L   SPY SGA   GC
Sbjct: 359 GSGGAAG-GYGGAGGGGSLGFFPSSLA-YSPYQSGAGPMGC 397

>CELR3_MOUSE (Q91ZI0) Cadherin EGF LAG seven-pass G-type receptor 3 precursor|
          Length = 3301

 Score = 29.6 bits (65), Expect = 4.9
 Identities = 23/75 (30%), Positives = 24/75 (32%), Gaps = 6/75 (8%)
 Frame = +3

Query: 300  CRMGCCPPMVDC----QIQSSAPRPPLHAPAQRHHRTLPLLAAAERAVLHRYC--RCFLV 461
            C  G CPP  DC    Q  S   RP  + P                      C   C L 
Sbjct: 1939 CASGPCPPHADCKDLWQTFSCTCRPGYYGPG---------------------CVDACLLN 1977

Query: 462  PVQRAGCCFHAQPAP 506
            P Q  G C H Q AP
Sbjct: 1978 PCQNQGSCRHLQGAP 1992

>FLCN_XENTR (Q5M7Q1) Folliculin|
          Length = 579

 Score = 29.6 bits (65), Expect = 4.9
 Identities = 10/18 (55%), Positives = 11/18 (61%)
 Frame = -1

Query: 247 CQLCHCHGPRSLICVHAL 194
           C  C  HGPR+L C  AL
Sbjct: 8   CHFCELHGPRTLFCTEAL 25

>PDZK3_RAT (Q9QZR8) PDZ domain-containing protein 3 (PDZ domain-containing|
            protein 2) (Plakophilin-related armadillo repeat
            protein-interacting PDZ protein)
          Length = 2766

 Score = 29.3 bits (64), Expect = 6.4
 Identities = 26/81 (32%), Positives = 30/81 (37%), Gaps = 13/81 (16%)
 Frame = -2

Query: 495  GHGSSNLPFGQEPES-NGNTGVAQPALPLPEAAGSGGVAGQGHAVE------------DV 355
            G+      F QEP S NG     +  LPL   AG  G A     VE            D 
Sbjct: 2635 GNDQPGPSFKQEPPSANGKGPFPRRTLPLEPGAGRNGAAHDALCVEVLKTSAGLGLSLDG 2694

Query: 354  GQTIGFGSQPLVDNSPYDSGA 292
            G++   G  PLV    Y  GA
Sbjct: 2695 GKSSVSGEGPLVIKRVYKGGA 2715

>BAF1_KLUMA (P33293) Transcription factor BAF1 (ARS-binding factor 1) (Protein|
           ABF1) (Bidirectionally acting factor)
          Length = 496

 Score = 29.3 bits (64), Expect = 6.4
 Identities = 18/76 (23%), Positives = 27/76 (35%), Gaps = 9/76 (11%)
 Frame = +1

Query: 139 APEIIIRNSRNHQRHNAARVHAHKSETEGHDNGRA---------DTQCNSDSEQAASMLR 291
           +P + + +   H  H+    H H     GH NG           + Q + + + AA    
Sbjct: 89  SPGVGVGDEHGHHHHHNMHAHHHHHHQNGHTNGHGNSGDDVSEQEAQQDDEDDDAAVTAA 148

Query: 292 CTAVVWAVVHQWLTAK 339
             A V AV     T K
Sbjct: 149 IAAAVAAVADSQETIK 164

>CLCF_ARATH (Q8RXR2) Chloride channel protein CLC-f (AtCLC-f)|
          Length = 781

 Score = 29.3 bits (64), Expect = 6.4
 Identities = 21/63 (33%), Positives = 32/63 (50%), Gaps = 2/63 (3%)
 Frame = -2

Query: 405 AAGS--GGVAGQGHAVEDVGQTIGFGSQPLVDNSPYDSGAPKHGCSLLRIGVALGVSSAI 232
           AAG   GG     H+V+D     GF  + L D++P +        +LL IG  +GV++ I
Sbjct: 92  AAGEEDGGGISNLHSVDDRNDEYGFDEEVLGDSAPPE-------WALLLIGCLIGVAAGI 144

Query: 231 VMA 223
            +A
Sbjct: 145 CVA 147

>TAF9_YEAST (Q05027) Transcription initiation factor TFIID subunit 9|
           (TBP-associated factor 9) (TBP-associated factor 17 kDa)
           (TAFII-17) (TAFII20)
          Length = 157

 Score = 28.9 bits (63), Expect = 8.3
 Identities = 16/37 (43%), Positives = 20/37 (54%)
 Frame = -2

Query: 438 GVAQPALPLPEAAGSGGVAGQGHAVEDVGQTIGFGSQ 328
           GV + AL   + AGSG  AG G  VED+   I   +Q
Sbjct: 66  GVLKDALVYNDYAGSGNSAGSGLGVEDIRLAIAARTQ 102

>NAF1_MOUSE (Q9WUU8) Nef-associated factor 1 (Naf1) (TNFAIP3-interacting|
           protein 1) (A20-binding inhibitor of NF-kappa B
           activation) (ABIN) (Virion-associated nuclear shuttling
           protein) (VAN) (mVAN)
          Length = 647

 Score = 28.9 bits (63), Expect = 8.3
 Identities = 13/21 (61%), Positives = 14/21 (66%)
 Frame = -2

Query: 429 QPALPLPEAAGSGGVAGQGHA 367
           QP+ P PE AG  GVAGQ  A
Sbjct: 276 QPSSPKPEGAGKKGVAGQQQA 296

>YB88_YEAST (P38330) Protein YBR238C|
          Length = 731

 Score = 28.9 bits (63), Expect = 8.3
 Identities = 18/71 (25%), Positives = 27/71 (38%)
 Frame = +1

Query: 58  QCNPTSRSTPRKGATAGLEFTTHPWLIAPEIIIRNSRNHQRHNAARVHAHKSETEGHDNG 237
           Q +P +   P  G   G     H      +    NS NH  HN  R H H +    H N 
Sbjct: 65  QVSPANHFVPHFGGNIGANNNNH----LAQNNSNNSNNH--HNNNRNHHHNNNRNHHQNN 118

Query: 238 RADTQCNSDSE 270
              ++ N+ ++
Sbjct: 119 HNHSKYNNSNQ 129

>MDC1_MOUSE (Q5PSV9) Mediator of DNA damage checkpoint protein 1|
          Length = 1707

 Score = 28.9 bits (63), Expect = 8.3
 Identities = 17/50 (34%), Positives = 23/50 (46%)
 Frame = -2

Query: 474 PFGQEPESNGNTGVAQPALPLPEAAGSGGVAGQGHAVEDVGQTIGFGSQP 325
           PFG   +++   G  QP +     A S G AG+    E  G T G  +QP
Sbjct: 215 PFGLGSDTDEEQG-QQPGVEESSLADSSGAAGEAEQPEANGTTAGIQAQP 263

>GATA2_ARATH (O49741) GATA transcription factor 2 (AtGATA-2)|
          Length = 264

 Score = 28.9 bits (63), Expect = 8.3
 Identities = 17/58 (29%), Positives = 26/58 (44%), Gaps = 1/58 (1%)
 Frame = +1

Query: 163 SRNHQRHNAARVHAHKSETEGHDNGRADTQCNS-DSEQAASMLRCTAVVWAVVHQWLT 333
           S + Q H+AA+    K ++ G   G    Q +S ++ +   M RCT        QW T
Sbjct: 137 SEHQQLHSAAKFKPKKEQSGGGGGGGGRHQSSSSETTEGGGMRRCTHCASEKTPQWRT 194

>VPF_BPMU (Q01259) F protein (gpF) (Protein gp30)|
          Length = 439

 Score = 28.9 bits (63), Expect = 8.3
 Identities = 23/82 (28%), Positives = 34/82 (41%), Gaps = 8/82 (9%)
 Frame = +1

Query: 64  NPTSRSTPRKGATAGLEFTTHPWLIA-PEIIIRNSRNHQ-------RHNAARVHAHKSET 219
           N  S +T    A    +    P L+A P+ ++ +  NHQ       R   AR+    S+T
Sbjct: 338 NGKSLATTADAALKPEDLQRLPSLMAKPQAVLWDRENHQLLYVVATRDGTARIVVRTSQT 397

Query: 220 EGHDNGRADTQCNSDSEQAASM 285
            G  N RAD   +     A S+
Sbjct: 398 VGRQNDRADVLVSISRVSAQSL 419

>FLCN_RAT (Q76JQ2) Folliculin (Birt-Hogg-Dube syndrome protein homolog)|
          Length = 579

 Score = 28.9 bits (63), Expect = 8.3
 Identities = 14/30 (46%), Positives = 18/30 (60%), Gaps = 4/30 (13%)
 Frame = -1

Query: 247 CQLCHCHGPRSLIC---VHA-LLRRCGAGD 170
           C  C  HGPR+L C   +HA L +  G+GD
Sbjct: 8   CHFCELHGPRTLFCTEVLHAPLPQGAGSGD 37

>FLCN_MOUSE (Q8QZS3) Folliculin|
          Length = 579

 Score = 28.9 bits (63), Expect = 8.3
 Identities = 14/30 (46%), Positives = 18/30 (60%), Gaps = 4/30 (13%)
 Frame = -1

Query: 247 CQLCHCHGPRSLIC---VHA-LLRRCGAGD 170
           C  C  HGPR+L C   +HA L +  G+GD
Sbjct: 8   CHFCELHGPRTLFCTEVLHAPLPQGAGSGD 37

>FLCN_HUMAN (Q8NFG4) Folliculin (Birt-Hogg-Dube syndrome protein) (BHD skin|
           lesion fibrofolliculoma protein)
          Length = 579

 Score = 28.9 bits (63), Expect = 8.3
 Identities = 11/26 (42%), Positives = 12/26 (46%)
 Frame = -1

Query: 247 CQLCHCHGPRSLICVHALLRRCGAGD 170
           C  C  HGPR+L C   L      GD
Sbjct: 8   CHFCELHGPRTLFCTEVLHAPLPQGD 33

>FLCN_BOVIN (Q3B7L5) Folliculin|
          Length = 579

 Score = 28.9 bits (63), Expect = 8.3
 Identities = 14/30 (46%), Positives = 18/30 (60%), Gaps = 4/30 (13%)
 Frame = -1

Query: 247 CQLCHCHGPRSLIC---VHA-LLRRCGAGD 170
           C  C  HGPR+L C   +HA L +  G+GD
Sbjct: 8   CHFCELHGPRTLFCTEVLHAPLPQGAGSGD 37


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 87,608,232
Number of Sequences: 219361
Number of extensions: 2015771
Number of successful extensions: 7242
Number of sequences better than 10.0: 21
Number of HSP's better than 10.0 without gapping: 6731
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7228
length of database: 80,573,946
effective HSP length: 104
effective length of database: 57,760,402
effective search space used: 3696665728
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)