>PKHA4_HUMAN (Q9H4M7) Pleckstrin homology domain-containing family A member 4|
            (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1)
          Length = 779

 Score = 34.7 bits (78), Expect = 0.16
 Identities = 31/124 (25%), Positives = 49/124 (39%), Gaps = 33/124 (26%)
 Frame = +3

Query: 60   GAWSKH-----YISSTESESNILLVLITRLHLDSFRWHTFLQGHT-----NHLPCVPTGI 209
            G+WS       Y+ ++E     +L L   L  ++ +WH  + G       + LP VP   
Sbjct: 651  GSWSSPRNTTPYLPTSEGHRERVLSLSQALATEASQWHRMMTGGNLDSQGDPLPGVPLPP 710

Query: 210  NGTAHRQLEQPRTPPLASY--------------APTP---------TCPPLPTDWSAQQL 320
            +    ++   PR+PP+A+                PTP           P LP D  A  L
Sbjct: 711  SDPTRQETPPPRSPPVANSGSTGFSRRGSGRGGGPTPWGPAWDAGIAPPVLPQDEGAWPL 770

Query: 321  RITV 332
            R+T+
Sbjct: 771  RVTL 774

>GAG_HTL1M (P14077) Gag polyprotein [Contains: Major core protein p19; Major|
           core protein p24; Nucleic acid-binding protein p15]
          Length = 428

 Score = 33.5 bits (75), Expect = 0.35
 Identities = 22/70 (31%), Positives = 27/70 (38%), Gaps = 1/70 (1%)
 Frame = +3

Query: 189 PCVPTGINGTAHRQLEQPRTPPLASYAPTPTCPPLPTDWSAQQLRITVALEASATSGSAI 368
           PC   G  G   R   QPR PP     P P C   PT W     R+   +        A+
Sbjct: 355 PCFRCGKAGHWSRDCTQPRPPP----GPCPLCQD-PTHWKRDCPRLKPTIPEPEPEEDAL 409

Query: 369 KISTP-DLPH 395
            +  P D+PH
Sbjct: 410 LLDLPADIPH 419

>GAG_HTL1C (P14076) Gag polyprotein [Contains: Major core protein p19; Major|
           core protein p24; Nucleic acid-binding protein p15]
          Length = 429

 Score = 33.5 bits (75), Expect = 0.35
 Identities = 22/70 (31%), Positives = 27/70 (38%), Gaps = 1/70 (1%)
 Frame = +3

Query: 189 PCVPTGINGTAHRQLEQPRTPPLASYAPTPTCPPLPTDWSAQQLRITVALEASATSGSAI 368
           PC   G  G   R   QPR PP     P P C   PT W     R+   +        A+
Sbjct: 356 PCFRCGKAGHWSRDCTQPRPPP----GPCPLCQD-PTHWKRDCPRLKPTIPEPEPEEDAL 410

Query: 369 KISTP-DLPH 395
            +  P D+PH
Sbjct: 411 LLDLPADIPH 420

>GAG_HTL1A (P03345) Gag polyprotein [Contains: Major core protein p19; Major|
           core protein p24; Nucleic acid-binding protein p15]
          Length = 429

 Score = 33.5 bits (75), Expect = 0.35
 Identities = 22/70 (31%), Positives = 27/70 (38%), Gaps = 1/70 (1%)
 Frame = +3

Query: 189 PCVPTGINGTAHRQLEQPRTPPLASYAPTPTCPPLPTDWSAQQLRITVALEASATSGSAI 368
           PC   G  G   R   QPR PP     P P C   PT W     R+   +        A+
Sbjct: 356 PCFRCGKAGHWSRDCTQPRPPP----GPCPLCQD-PTHWKRDCPRLKPTIPEPEPEEDAL 410

Query: 369 KISTP-DLPH 395
            +  P D+PH
Sbjct: 411 LLDLPADIPH 420

>SOX30_MACFA (Q8WNV5) Transcription factor SOX-30|
          Length = 753

 Score = 32.0 bits (71), Expect = 1.0
 Identities = 23/87 (26%), Positives = 33/87 (37%), Gaps = 4/87 (4%)
 Frame = +1

Query: 145 PSVGILFFKAIQT----IYPASLPESMARPTDS*NNQEHRR*LAMPQLPLVLHCRPTGAH 312
           PSV      A+Q     +YPA  P+  A P+ +  +Q H       + P  +    T   
Sbjct: 487 PSVSSAAQVAVQDPSLPLYPALPPQRFAGPSQTDTHQLHSEGTHTVKQPTPVSLESTNRI 546

Query: 313 SNSGSXXXXXXXXXAVQPSKSALQIYP 393
           SNS S          +QP K    + P
Sbjct: 547 SNSASTAHARFATSTIQPPKEYSSVSP 573

>MUC5B_HUMAN (Q9HC84) Mucin-5B precursor (Mucin 5 subtype B, tracheobronchial)|
            (High molecular weight salivary mucin MG1) (Sublingual
            gland mucin)
          Length = 5703

 Score = 30.8 bits (68), Expect = 2.3
 Identities = 19/70 (27%), Positives = 26/70 (37%)
 Frame = +3

Query: 183  HLPCVPTGINGTAHRQLEQPRTPPLASYAPTPTCPPLPTDWSAQQLRITVALEASATSGS 362
            ++PC P+   GT+ +      T P        T     T W    +R T AL +   S S
Sbjct: 1430 YVPCGPSPAPGTSPQPSLSASTEPAVPTPTQTTATEKTTLWVTPSIRSTAALTSQTGSSS 1489

Query: 363  AIKISTPDLP 392
                 TP  P
Sbjct: 1490 GPVTVTPSAP 1499

>HOMEZ_HUMAN (Q8IX15) Homeobox and leucine zipper protein Homez (Homeodomain|
           leucine zipper-containing factor)
          Length = 525

 Score = 30.4 bits (67), Expect = 3.0
 Identities = 22/57 (38%), Positives = 26/57 (45%), Gaps = 1/57 (1%)
 Frame = +3

Query: 189 PCVPTGINGTAHRQLEQPRTPPLASYAPTPTCPPLPTDWSA-QQLRITVALEASATS 356
           P +PT    T     E+  TPPL    P P   PL   W+A QQLR T   + S  S
Sbjct: 409 PAIPTPPPSTRSLN-ERAETPPLPIPPPPPDIQPLERYWAAHQQLRETDIPQLSQAS 464

>ATG26_CRYNE (Q5KK25) Sterol 3-beta-glucosyltransferase (EC 2.4.1.173)|
            (Autophagy-related protein 26)
          Length = 1585

 Score = 30.4 bits (67), Expect = 3.0
 Identities = 18/62 (29%), Positives = 29/62 (46%), Gaps = 1/62 (1%)
 Frame = +3

Query: 123  ITRLHLDSFRWHTFLQGHTNHLPCVPTGINGTAHRQLEQPRTPPLASYAPTPTCPPLP-T 299
            +T    D   W   + G  N       G++ T   ++EQ + P L +++PT   PPL  T
Sbjct: 1188 MTYTMFDQVFWRA-ISGQVNRWRRNVLGLDATTFDKMEQHKVPFLYNFSPTVVPPPLDWT 1246

Query: 300  DW 305
            +W
Sbjct: 1247 EW 1248

>ARHGF_HUMAN (O94989) Rho guanine nucleotide exchange factor 15 (Vsm-RhoGEF)|
          Length = 841

 Score = 30.4 bits (67), Expect = 3.0
 Identities = 18/60 (30%), Positives = 26/60 (43%)
 Frame = +3

Query: 213 GTAHRQLEQPRTPPLASYAPTPTCPPLPTDWSAQQLRITVALEASATSGSAIKISTPDLP 392
           G  H        P  ++ APTP C P+  +  A  L+    L  SA+  S    ++PD P
Sbjct: 35  GPPHNGSSPQELPRNSNDAPTPMCTPIFWEPPAASLKPPALLPPSASRASLDSQTSPDSP 94

>WASF1_HUMAN (Q92558) Wiskott-Aldrich syndrome protein family member 1|
           (WASP-family protein member 1) (WAVE-1 protein)
           (Verprolin homology domain-containing protein 1)
          Length = 559

 Score = 30.0 bits (66), Expect = 3.9
 Identities = 23/77 (29%), Positives = 29/77 (37%), Gaps = 3/77 (3%)
 Frame = +3

Query: 171 GHTNHLPCVPTGINGTAHRQLEQP---RTPPLASYAPTPTCPPLPTDWSAQQLRITVALE 341
           G    +P   +   G    + + P   RTP   S  P P  PPLP+  S   LR      
Sbjct: 288 GDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALSTSSLR------ 341

Query: 342 ASATSGSAIKISTPDLP 392
           AS TS     +  P  P
Sbjct: 342 ASMTSTPPPPVPPPPPP 358

>E75BB_DROME (P13055) Ecdysone-induced protein 75B isoform B (E75-C)|
          Length = 1412

 Score = 30.0 bits (66), Expect = 3.9
 Identities = 19/56 (33%), Positives = 23/56 (41%), Gaps = 5/56 (8%)
 Frame = +3

Query: 165 LQGHTNHLPCVPT-----GINGTAHRQLEQPRTPPLASYAPTPTCPPLPTDWSAQQ 317
           L  H+   P  P      G      +Q +Q +TPPLA   P P  PP P     QQ
Sbjct: 232 LHHHSRSAPVSPVIARRGGAAAYMDQQYQQRQTPPLAPPPPPPPPPPPPPPPQQQQ 287

>MLL3_HUMAN (Q8NEZ4) Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog|
            (Histone-lysine N-methyltransferase, H3 lysine-4 specific
            MLL3) (EC 2.1.1.43) (Homologous to ALR protein)
          Length = 4911

 Score = 29.6 bits (65), Expect = 5.0
 Identities = 17/50 (34%), Positives = 23/50 (46%), Gaps = 4/50 (8%)
 Frame = +3

Query: 159  TFLQGHTN--HLPCVP--TGINGTAHRQLEQPRTPPLASYAPTPTCPPLP 296
            T + GHT+   +P +P     +  AH  L  PR  P  +  P  TC P P
Sbjct: 3318 TVISGHTSPVRMPSLPGWQPNSAPAHLPLNPPRIQPPIAQLPIKTCTPAP 3367

>YCX7_CHLRE (P36495) 232.2 kDa protein (ORF1995) (ORF-S) (ORFA)|
          Length = 1995

 Score = 29.6 bits (65), Expect = 5.0
 Identities = 13/48 (27%), Positives = 24/48 (50%)
 Frame = +3

Query: 75  HYISSTESESNILLVLITRLHLDSFRWHTFLQGHTNHLPCVPTGINGT 218
           H+++  E  +  +   +   H D+ RW+T++Q    H   + T I GT
Sbjct: 857 HFLTKNEERALHIRRFLLSEHYDTLRWYTYMQ----HYKTMKTNIGGT 900

>PABPA_XENLA (P20965) Polyadenylate-binding protein 1-A (Poly(A)-binding protein|
           1-A) (Cytoplasmic poly(A)-binding protein 1-A) (PABP-A)
           (PABP 1-A) (xPABP1-A)
          Length = 633

 Score = 29.6 bits (65), Expect = 5.0
 Identities = 19/63 (30%), Positives = 29/63 (46%)
 Frame = +2

Query: 170 RPYKPSTLRPYRNQWHGPQTARTTKNTAAS*LCPNSHLSSIADRLERTATPDHSGAGGVG 349
           RP   ST+RP  NQ     +A+   NT+   + P    ++ A      A P +  A GV 
Sbjct: 458 RPPTFSTMRPASNQVPRVMSAQRVANTSTQTMGPRPTTAAAAAASAVRAVPQYKYAAGVR 517

Query: 350 NKR 358
           N++
Sbjct: 518 NQQ 520

>MLL3_MOUSE (Q8BRH4) Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog|
            (Histone-lysine N-methyltransferase, H3 lysine-4 specific
            MLL3) (EC 2.1.1.43)
          Length = 4903

 Score = 29.6 bits (65), Expect = 5.0
 Identities = 29/91 (31%), Positives = 40/91 (43%), Gaps = 5/91 (5%)
 Frame = +3

Query: 39   QPPIYGPGAWSKHYISSTESESNILLVLITRLHLDSFRWHT-FLQGHTN--HLPCVP--T 203
            QPP+  PGA      S T S+ N  +V     H    + HT  + GHT+   +P +P   
Sbjct: 3283 QPPLV-PGA-----TSLTMSQPNFPMVPQQLQH----QQHTAVISGHTSPARMPSLPGWQ 3332

Query: 204  GINGTAHRQLEQPRTPPLASYAPTPTCPPLP 296
              + +AH  L  PR  P  +     TC P P
Sbjct: 3333 SNSASAHLPLNPPRIQPPIAQLSLKTCTPAP 3363

>BCL9_HUMAN (O00512) B-cell lymphoma 9 protein (Bcl-9) (Legless homolog)|
          Length = 1426

 Score = 29.6 bits (65), Expect = 5.0
 Identities = 13/38 (34%), Positives = 18/38 (47%)
 Frame = +3

Query: 189 PCVPTGINGTAHRQLEQPRTPPLASYAPTPTCPPLPTD 302
           P VP   +  + +      TPP+ + AP P  PP P D
Sbjct: 238 PPVPANQDQNSSQNTRLQPTPPIPAPAPKPAAPPRPLD 275

>CDKL5_HUMAN (O76039) Cyclin-dependent kinase-like 5 (EC 2.7.11.22)|
            (Serine/threonine-protein kinase 9)
          Length = 1030

 Score = 29.3 bits (64), Expect = 6.6
 Identities = 14/37 (37%), Positives = 16/37 (43%)
 Frame = +3

Query: 183  HLPCVPTGINGTAHRQLEQPRTPPLASYAPTPTCPPL 293
            H PCVP   N   HR +  P   P+     T  CP L
Sbjct: 945  HTPCVP---NRALHRPISSPAPYPVLQVRGTSMCPTL 978

>NUMBL_HUMAN (Q9Y6R0) Numb-like protein (Numb-R)|
          Length = 609

 Score = 29.3 bits (64), Expect = 6.6
 Identities = 16/61 (26%), Positives = 25/61 (40%)
 Frame = +3

Query: 189 PCVPTGINGTAHRQLEQPRTPPLASYAPTPTCPPLPTDWSAQQLRITVALEASATSGSAI 368
           P +P+     A  +      PP  + AP P   P    W+A + + TV   ++  SG   
Sbjct: 543 PAIPSAPGSQARPRPNGAPWPPEPAPAPAPELDPFEAQWAALEGKATVEKPSNPFSGDLQ 602

Query: 369 K 371
           K
Sbjct: 603 K 603

>GLI1_HUMAN (P08151) Zinc finger protein GLI1 (Glioma-associated oncogene)|
           (Oncogene GLI)
          Length = 1106

 Score = 29.3 bits (64), Expect = 6.6
 Identities = 22/78 (28%), Positives = 34/78 (43%)
 Frame = +2

Query: 89  DRKRKQHTTSTNYTPTFGFLPLAYFSSRPYKPSTLRPYRNQWHGPQTARTTKNTAAS*LC 268
           DR + Q+ T +N  P    LP    + R   PS+LR +    HGP    T ++     L 
Sbjct: 347 DRAKHQNRTHSNEKPYVCKLPGC--TKRYTDPSSLRKHVKTVHGPDAHVTKRHRGDGPLP 404

Query: 269 PNSHLSSIADRLERTATP 322
               +S++  + ER   P
Sbjct: 405 RAPSISTVEPKREREGGP 422

>PROML_DROME (P82295) Prominin-like protein|
          Length = 1013

 Score = 28.9 bits (63), Expect = 8.6
 Identities = 16/35 (45%), Positives = 18/35 (51%), Gaps = 5/35 (14%)
 Frame = +3

Query: 210 NGTAHRQLEQPRTPPL--ASYAPTPT---CPPLPT 299
           +GT H QL QP  PP+    Y PT      PP PT
Sbjct: 74  HGTTHEQLGQPHWPPVQYTVYRPTTNYTKAPPPPT 108

>WASF1_MOUSE (Q8R5H6) Wiskott-Aldrich syndrome protein family member 1|
           (WASP-family protein member 1) (WAVE-1 protein)
          Length = 559

 Score = 28.9 bits (63), Expect = 8.6
 Identities = 23/77 (29%), Positives = 28/77 (36%), Gaps = 3/77 (3%)
 Frame = +3

Query: 171 GHTNHLPCVPTGINGTAHRQLEQP---RTPPLASYAPTPTCPPLPTDWSAQQLRITVALE 341
           G     P   +   G    + + P   RTP   S  P P  PPLP+  S   LR      
Sbjct: 288 GDAKPTPTCISSATGLIENRPQSPAAGRTPVFVSPTPPPPPPPLPSALSTSSLR------ 341

Query: 342 ASATSGSAIKISTPDLP 392
           AS TS     +  P  P
Sbjct: 342 ASMTSTPPPPVPPPPPP 358

>HOMEZ_MOUSE (Q80W88) Homeobox and leucine zipper protein Homez (Homeodomain|
           leucine zipper-containing factor)
          Length = 518

 Score = 28.9 bits (63), Expect = 8.6
 Identities = 20/57 (35%), Positives = 27/57 (47%), Gaps = 1/57 (1%)
 Frame = +3

Query: 189 PCVPTGINGTAHRQLEQPRTPPLASYAPTPTCPPLPTDWSA-QQLRITVALEASATS 356
           P +PT    +     E  +TPPL +  P P   PL   W+A QQL+    L+ S  S
Sbjct: 403 PAIPTP---STRSLKEWAKTPPLPAPPPPPDIRPLEKYWAAHQQLQEADILKLSQAS 456

>WBS14_MOUSE (Q99MZ3) Williams-Beuren syndrome chromosome region 14 protein|
           homolog (Mlx interactor) (MLX-interacting protein-like)
          Length = 864

 Score = 28.9 bits (63), Expect = 8.6
 Identities = 25/83 (30%), Positives = 37/83 (44%), Gaps = 8/83 (9%)
 Frame = +2

Query: 65  MEQTLHFIDRKRKQHTTSTNY--TPTFGFLPLAYFSSRPYKPSTLRPYRNQW------HG 220
           ME +  F + +  Q  TS+NY  +P+FG +  + FSS    P    P  +        H 
Sbjct: 297 MEISDFFTNYRPPQTPTSSNYIESPSFGPMADSLFSSGILAPEMPSPASSSSSSGMTPHS 356

Query: 221 PQTARTTKNTAAS*LCPNSHLSS 289
             T    +N+ +  L PN  LSS
Sbjct: 357 GNTRLQARNSCSGPLDPNPFLSS 379

>BAT2_RAT (Q6MG48) Large proline-rich protein BAT2 (HLA-B-associated|
           transcript 2)
          Length = 2161

 Score = 28.9 bits (63), Expect = 8.6
 Identities = 21/70 (30%), Positives = 29/70 (41%), Gaps = 2/70 (2%)
 Frame = +3

Query: 189 PCVPTGINGTAHRQLEQPRTPPLASYAPTPTCPPLPTDWSAQQLRITVALEASATSGSAI 368
           P +P     T  +  E+P   P    APT   PP PT        ++    AS+TS  + 
Sbjct: 531 PALPPTPTPTPEKDPEEPAHAPPVQSAPTQAGPPAPTP-------VSGGGTASSTSSGSF 583

Query: 369 KIS--TPDLP 392
           + S   P LP
Sbjct: 584 EASPAEPQLP 593

>SIR4_YEAST (P11978) Regulatory protein SIR4 (Silent information regulator 4)|
          Length = 1358

 Score = 28.9 bits (63), Expect = 8.6
 Identities = 12/28 (42%), Positives = 20/28 (71%)
 Frame = +3

Query: 174 HTNHLPCVPTGINGTAHRQLEQPRTPPL 257
           HT+  P  P+ +  T+H+QL+QP++ PL
Sbjct: 61  HTS--PHQPSDVKPTSHKQLQQPKSSPL 86


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 79,322,766
Number of Sequences: 219361
Number of extensions: 1625217
Number of successful extensions: 5338
Number of sequences better than 10.0: 25
Number of HSP's better than 10.0 without gapping: 4600
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5279
length of database: 80,573,946
effective HSP length: 104
effective length of database: 57,760,402
effective search space used: 3812186532
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)