>GRN_MOUSE (P28798) Granulins precursor (Proepithelin) (PEPI) (PC cell-derived|
           growth factor) (PCDGF) [Contains: Acrogranin;
           Granulin-1; Granulin-2; Granulin-3; Granulin-4;
           Granulin-5; Granulin-6; Granulin-7]
          Length = 589

 Score = 33.1 bits (74), Expect = 0.41
 Identities = 19/81 (23%), Positives = 27/81 (33%)
 Frame = +1

Query: 205 CRDAGCSCCYYTRQCCWVQASLVGRPVNVVCHR*PWQERLASCRAPWIGEIALQHRCPRP 384
           C  A   CC     CC         P    CH       +   + PW+ ++    R P P
Sbjct: 305 CPFAKAVCCEDHIHCC---------PAGFQCHTEKGTCEMGILQVPWMKKVIAPLRLPDP 355

Query: 385 SASQPVSPCHPLTTFPISAVC 447
              +  +PC   T  P +  C
Sbjct: 356 QILKSDTPCDDFTRCPTNNTC 376

>KR10B_HUMAN (P60412) Keratin-associated protein 10-11 (Keratin-associated|
           protein 10.11) (High sulfur keratin-associated protein
           10.11) (Keratin-associated protein 18-11)
           (Keratin-associated protein 18.11)
          Length = 298

 Score = 33.1 bits (74), Expect = 0.41
 Identities = 24/92 (26%), Positives = 36/92 (39%), Gaps = 4/92 (4%)
 Frame = +1

Query: 184 SCMPTSSCRDAGCSCCYYTRQCCWVQASLVGRPVNVVCHR*PWQERLASCRAPWIGEIAL 363
           SC   SSC+ A C+   Y + CC            + C     +   + C+ P       
Sbjct: 167 SCCQQSSCQPACCTSSSYQQACCVPVCCKTVYCKPICCVPVCSRASYSRCQQPSCQPACC 226

Query: 364 QHRCPRPSASQPVSPCHPL----TTFPISAVC 447
              C RPS+S  +  CHP+       P+S+ C
Sbjct: 227 TTSCCRPSSSVSLL-CHPVCRSTCCVPVSSCC 257

>CN065_HUMAN (Q8N9R9) Protein C14orf65|
          Length = 162

 Score = 31.6 bits (70), Expect = 1.2
 Identities = 26/78 (33%), Positives = 35/78 (44%), Gaps = 10/78 (12%)
 Frame = +1

Query: 247 CCWVQASLVGRPVNVVCHR*PWQERLASCRAPWIGEIALQHRCP------RPSASQPVS- 405
           C W++A+L        C   PW+   + C   W G + L H  P      R S S PVS 
Sbjct: 84  CGWLEAAL-----GPSCDPQPWR---SGCPHTW-GSV-LSHPMPAAPCFWRSSPSPPVSA 133

Query: 406 --PCHPLTTFP-ISAVCP 450
             PCHP+   P + + CP
Sbjct: 134 MSPCHPVQAMPFLGSSCP 151

>KRA15_HUMAN (Q9BYS1) Keratin-associated protein 1-5 (Keratin-associated protein|
           1.5) (High sulfur keratin-associated protein 1.5)
          Length = 174

 Score = 31.2 bits (69), Expect = 1.6
 Identities = 19/52 (36%), Positives = 22/52 (42%), Gaps = 5/52 (9%)
 Frame = +1

Query: 112 GLFLPPCC*WIKTSSFHLNTLMVGSCMPTSSCR--DAGCSCC---YYTRQCC 252
           G +LPPCC              V SC P S C+   A  SCC   Y  + CC
Sbjct: 127 GTYLPPCC--------------VVSCTPPSCCQLHHAQASCCRPSYCGQSCC 164

>NHR35_CAEEL (Q17771) Nuclear hormone receptor family member nhr-35|
          Length = 542

 Score = 30.8 bits (68), Expect = 2.1
 Identities = 10/42 (23%), Positives = 25/42 (59%)
 Frame = -3

Query: 431 GKVVNGWHGETGCEADGRGHRCCNAISPIQGALHDASLSCHG 306
           G+++  ++G++  E DG+ +  C+  S +    H  +++C+G
Sbjct: 55  GQMLGTYNGDSKAETDGKDNSICHICSDVATGRHYGAIACNG 96

>PYR1_HUMAN (P27708) CAD protein [Includes: Glutamine-dependent|
           carbamoyl-phosphate synthase (EC 6.3.5.5); Aspartate
           carbamoyltransferase (EC 2.1.3.2); Dihydroorotase (EC
           3.5.2.3)]
          Length = 2225

 Score = 30.4 bits (67), Expect = 2.7
 Identities = 11/24 (45%), Positives = 15/24 (62%)
 Frame = +1

Query: 133 C*WIKTSSFHLNTLMVGSCMPTSS 204
           C W ++S  H+  L+VG C PT S
Sbjct: 73  CKWFESSGIHVAALVVGECCPTPS 96

>KR131_HUMAN (Q8IUC0) Keratin-associated protein 13-1 (High sulfur|
           keratin-associated protein 13.1)
          Length = 172

 Score = 30.4 bits (67), Expect = 2.7
 Identities = 20/73 (27%), Positives = 29/73 (39%)
 Frame = +1

Query: 193 PTSSCRDAGCSCCYYTRQCCWVQASLVGRPVNVVCHR*PWQERLASCRAPWIGEIALQHR 372
           P SSC  +  S   Y+   C      +G  +   C +  W+    SC+  ++     Q  
Sbjct: 22  PASSCGFSYPSNQVYSTDLCSPSTCQLGSSLYRGCQQTCWEP--TSCQTSYVESSPCQTS 79

Query: 373 CPRPSASQPVSPC 411
           C RP  S   SPC
Sbjct: 80  CYRPRTSLLCSPC 92

>KRA43_HUMAN (Q9BYR4) Keratin-associated protein 4-3 (Keratin-associated protein|
           4.3) (Ultrahigh sulfur keratin-associated protein 4.3)
           (Fragment)
          Length = 98

 Score = 30.4 bits (67), Expect = 2.7
 Identities = 19/74 (25%), Positives = 29/74 (39%)
 Frame = +1

Query: 124 PPCC*WIKTSSFHLNTLMVGSCMPTSSCRDAGCSCCYYTRQCCWVQASLVGRPVNVVCHR 303
           P CC         +++    SC  T+ CR + C    Y  QCC          ++  CH 
Sbjct: 15  PSCC---------ISSCCKPSCCQTTCCRPSCCISSCYRPQCCQPSCCRPACCISSCCHP 65

Query: 304 *PWQERLASCRAPW 345
                 ++SCR P+
Sbjct: 66  ---SCCVSSCRCPF 76

>GRN_RAT (P23785) Granulins precursor [Contains: Acrogranin; Granulin-1|
           (Granulin G); Granulin-2 (Granulin F); Granulin-3
           (Granulin B) (Epithelin-2); Granulin-4 (Granulin A)
           (Epithelin-1); Granulin-5 (Granulin C); Granulin-6
           (Granulin D); Granulin-7 (Gran
          Length = 588

 Score = 30.0 bits (66), Expect = 3.5
 Identities = 16/74 (21%), Positives = 28/74 (37%)
 Frame = +1

Query: 226 CCYYTRQCCWVQASLVGRPVNVVCHR*PWQERLASCRAPWIGEIALQHRCPRPSASQPVS 405
           CC +T+  C  +  +   P    CH       L   + PW+ ++      P P   +   
Sbjct: 303 CCPFTKAVC-CEDHIHCCPAGFQCHTETGTCELGVLQVPWMKKVTASLSLPDPQILKNDV 361

Query: 406 PCHPLTTFPISAVC 447
           PC   ++ P +  C
Sbjct: 362 PCDDFSSCPSNNTC 375

>KRA49_HUMAN (Q9BYQ8) Keratin-associated protein 4-9 (Keratin-associated protein|
           4.9) (Ultrahigh sulfur keratin-associated protein 4.9)
           (Fragment)
          Length = 191

 Score = 30.0 bits (66), Expect = 3.5
 Identities = 31/98 (31%), Positives = 35/98 (35%), Gaps = 6/98 (6%)
 Frame = +1

Query: 184 SCMPTSSCRDAGC--SCCYYTRQCCWVQA--SLVGRPVNVVCHR*PWQERLASCRAPWIG 351
           SC  T+ CR   C  SCC     CC  Q   S+  +P    C R P   +   CR     
Sbjct: 9   SCCETTCCRTTCCRPSCC--VSSCCRPQCCQSVCCQP---TCSR-PSCCQTTCCRTTCYR 62

Query: 352 EIALQHRCPRPSASQPVSPCHPLTTFP--ISAVCPHYR 459
                  C RP   QPV  C P    P      C H R
Sbjct: 63  PSCCVSSCCRPQCCQPVC-CQPTCCRPSCCETTCCHPR 99

>PYR1_MESAU (P08955) CAD protein [Includes: Glutamine-dependent|
           carbamoyl-phosphate synthase (EC 6.3.5.5); Aspartate
           carbamoyltransferase (EC 2.1.3.2); Dihydroorotase (EC
           3.5.2.3)]
          Length = 2225

 Score = 29.3 bits (64), Expect = 6.0
 Identities = 13/36 (36%), Positives = 20/36 (55%)
 Frame = +1

Query: 139 WIKTSSFHLNTLMVGSCMPTSSCRDAGCSCCYYTRQ 246
           W ++S  H+  L+VG C PT S   A C+   + +Q
Sbjct: 75  WFESSENHVAGLVVGECCPTPSHWSATCTLHEWLQQ 110

>MT3_PIG (P55944) Metallothionein-3 (MT-3) (Metallothionein-III) (MT-III)|
           (Growth inhibitory factor) (GIF)
          Length = 68

 Score = 29.3 bits (64), Expect = 6.0
 Identities = 10/24 (41%), Positives = 12/24 (50%)
 Frame = +1

Query: 181 GSCMPTSSCRDAGCSCCYYTRQCC 252
           GSC    SC+  GC C    + CC
Sbjct: 12  GSCTCAGSCKCEGCKCTSCKKSCC 35

>MT3_HUMAN (P25713) Metallothionein-3 (MT-3) (Metallothionein-III) (MT-III)|
           (Growth inhibitory factor) (GIF) (GIFB)
          Length = 68

 Score = 29.3 bits (64), Expect = 6.0
 Identities = 10/24 (41%), Positives = 12/24 (50%)
 Frame = +1

Query: 181 GSCMPTSSCRDAGCSCCYYTRQCC 252
           GSC    SC+  GC C    + CC
Sbjct: 12  GSCTCADSCKCEGCKCTSCKKSCC 35

>MT1_MOUSE (P02802) Metallothionein-1 (MT-1) (Metallothionein-I) (MT-I)|
          Length = 61

 Score = 29.3 bits (64), Expect = 6.0
 Identities = 11/24 (45%), Positives = 12/24 (50%)
 Frame = +1

Query: 181 GSCMPTSSCRDAGCSCCYYTRQCC 252
           GSC  TSSC    C C    + CC
Sbjct: 11  GSCTCTSSCACKNCKCTSCKKSCC 34


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 69,517,374
Number of Sequences: 219361
Number of extensions: 1352194
Number of successful extensions: 3999
Number of sequences better than 10.0: 14
Number of HSP's better than 10.0 without gapping: 3714
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3978
length of database: 80,573,946
effective HSP length: 104
effective length of database: 57,760,402
effective search space used: 3465624120
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)