ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | rbart06d10 |
|---|---|
| Clone Library Name | barley_pub |
>C72A1_CATRO (Q05047) Cytochrome P450 72A1 (EC 1.3.3.9) (CYPLXXII) (Secologanin| synthase) (SLS) Length = 524 Score = 133 bits (334), Expect = 3e-31 Identities = 60/129 (46%), Positives = 86/129 (66%) Frame = -3 Query: 460 PVAAIQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAG 281 PV + + D ++G +P GT + +P +HR+K +WGEDA EF P+RF +GV A Sbjct: 395 PVIDLTKIVHKDTKLGSYTIPAGTQVMLPTVMLHREKSIWGEDAMEFNPMRFVDGVANAT 454 Query: 280 KHPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITLRPKFG 101 K+ L FS GPR C+GQNFA+++AK +AMILQRF F ++P YVHAP ++T++P+FG Sbjct: 455 KNNVTYLPFSWGPRVCLGQNFALLQAKLGLAMILQRFKFDVAPSYVHAPFTILTVQPQFG 514 Query: 100 LPMILKSPE 74 +I K E Sbjct: 515 SHVIYKKLE 523
>CP4B1_RAT (P15129) Cytochrome P450 4B1 (EC 1.14.14.1) (CYPIVB1) (P450-isozyme| 5) (P450 L-2) Length = 510 Score = 92.4 bits (228), Expect = 5e-19 Identities = 53/127 (41%), Positives = 74/127 (58%), Gaps = 1/127 (0%) Frame = -3 Query: 460 PVAAIQRKAGSDLE-VGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRA 284 PV + R+ + V G +P G++I++ I +HR+ VW D F PLRF + A Sbjct: 378 PVPQVYRQLNKPVTFVDGRSLPAGSLISLHIYALHRNSTVW-PDPEVFDPLRF-SPENAA 435 Query: 283 GKHPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITLRPKF 104 G+HP A + FS+GPR+CIGQ FAM E K V A+ L RF FSL P + + + LR K Sbjct: 436 GRHPFAFMPFSAGPRNCIGQQFAMNEMKVVTALCLLRFEFSLDPSKMPIKVPQLILRSKN 495 Query: 103 GLPMILK 83 G+ + LK Sbjct: 496 GIHLYLK 502
>CP4B1_RABIT (P15128) Cytochrome P450 4B1 (EC 1.14.14.1) (CYPIVB1) (P450-isozyme| 5) Length = 506 Score = 92.0 bits (227), Expect = 7e-19 Identities = 51/127 (40%), Positives = 75/127 (59%), Gaps = 1/127 (0%) Frame = -3 Query: 460 PVAAIQRKAGSDLE-VGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRA 284 PV + R+ + V G +P G++I++ I +HR+ +VW D F PLRF + + Sbjct: 374 PVPQVYRQLSKPVSFVDGRSLPAGSLISLHIYALHRNSDVW-PDPEVFDPLRF-SPENSS 431 Query: 283 GKHPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITLRPKF 104 G+HP A + FS+GPR+CIGQ FAM E K V A+ L RF FS+ P + + + LR K Sbjct: 432 GRHPYAFIPFSAGPRNCIGQQFAMNEMKVVTALCLLRFEFSVDPLRLPIKLPQLVLRSKN 491 Query: 103 GLPMILK 83 G+ + LK Sbjct: 492 GIHLYLK 498
>CP4B1_MOUSE (Q64462) Cytochrome P450 4B1 (EC 1.14.14.1) (CYPIVB1)| Length = 511 Score = 89.0 bits (219), Expect = 6e-18 Identities = 51/127 (40%), Positives = 72/127 (56%), Gaps = 1/127 (0%) Frame = -3 Query: 460 PVAAIQRKAGSDLE-VGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRA 284 PV + R+ + V G +P G++I++ I +HR+ VW D F PLRF + Sbjct: 379 PVPQVYRQLSKPVTFVDGRSLPAGSLISLHIYALHRNSAVW-PDPEVFDPLRF-SPENMT 436 Query: 283 GKHPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITLRPKF 104 G+HP A + FS+GPR+CIGQ FAM E K V A+ L RF FS P + + + LR K Sbjct: 437 GRHPFAFMPFSAGPRNCIGQQFAMNEMKVVTALCLLRFEFSPDPSKIPIKVPQLILRSKN 496 Query: 103 GLPMILK 83 G+ + LK Sbjct: 497 GIHLYLK 503
>CP4B1_HUMAN (P13584) Cytochrome P450 4B1 (EC 1.14.14.1) (CYPIVB1) (P450-HP)| Length = 511 Score = 87.0 bits (214), Expect = 2e-17 Identities = 52/127 (40%), Positives = 70/127 (55%), Gaps = 1/127 (0%) Frame = -3 Query: 460 PVAAIQRKAGSDLE-VGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRA 284 PV + R+ + V G +P G++I++ I +HR+ VW D F LRF + Sbjct: 379 PVPQVYRQLSKPVTFVDGRSLPAGSLISMHIYALHRNSAVW-PDPEVFDSLRFSTE-NAS 436 Query: 283 GKHPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITLRPKF 104 +HP A + FS+GPR+CIGQ FAM E K V AM L RF FSL P + M + LR K Sbjct: 437 KRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSRLPIKMPQLVLRSKN 496 Query: 103 GLPMILK 83 G + LK Sbjct: 497 GFHLHLK 503
>CP3AO_SHEEP (Q29496) Cytochrome P450 3A24 (EC 1.14.14.1) (CYPIIIA24)| Length = 503 Score = 84.3 bits (207), Expect = 1e-16 Identities = 41/100 (41%), Positives = 60/100 (60%), Gaps = 1/100 (1%) Frame = -3 Query: 460 PVAA-IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRA 284 P+A + R D+E+ G+ +PKGT +T+PI +HRD ++W E EF+P RF + Sbjct: 368 PIAVRLDRLCKKDVEIHGVSIPKGTAVTVPIFVLHRDPQLWPE-PEEFRPERFSK-KNKD 425 Query: 283 GKHPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSF 164 +P L F +GPR+CIG FA++ K I +LQ FSF Sbjct: 426 SINPYVYLPFGTGPRNCIGMRFAIMNMKLAIVRVLQNFSF 465
>CP3AT_PIG (P79401) Cytochrome P450 3A29 (EC 1.14.14.1) (CYPIIIA29)| Length = 503 Score = 83.6 bits (205), Expect = 2e-16 Identities = 41/100 (41%), Positives = 62/100 (62%), Gaps = 1/100 (1%) Frame = -3 Query: 460 PVAA-IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRA 284 P+AA ++R D+E+ G+ VPKGTV+ +P+ +HRD ++W E EF+P RF + Sbjct: 368 PIAARLERACKKDVEIHGVFVPKGTVVVVPVFVLHRDPDLWPE-PEEFRPERFSK-KHKD 425 Query: 283 GKHPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSF 164 +P L F +GPR+CIG FA++ K + +LQ FSF Sbjct: 426 TINPYTYLPFGTGPRNCIGMRFALMNMKLALVRVLQNFSF 465
>CP3AC_CANFA (P24463) Cytochrome P450 3A12 (EC 1.14.14.1) (CYPIIIA12)| (P450-PBD-1) Length = 503 Score = 83.2 bits (204), Expect = 3e-16 Identities = 40/100 (40%), Positives = 61/100 (61%), Gaps = 1/100 (1%) Frame = -3 Query: 460 PVAA-IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRA 284 P+A ++R D+E+ G+ +PKGTV+ +P T+HRD+ +W E EF+P RF + Sbjct: 368 PIAGRLERVCKKDVEISGVFIPKGTVVMVPTFTLHRDQSLWPE-PEEFRPERFSR-KNKD 425 Query: 283 GKHPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSF 164 +P L F +GPR+CIG FA++ K + +LQ FSF Sbjct: 426 SINPYTYLPFGTGPRNCIGMRFAIMNMKLALVRVLQNFSF 465
>CP3AJ_CAPAE (P79152) Cytochrome P450 3A19 (EC 1.14.14.1) (CYPIIIA19) (Fragment)| Length = 218 Score = 80.9 bits (198), Expect = 2e-15 Identities = 41/115 (35%), Positives = 65/115 (56%), Gaps = 1/115 (0%) Frame = -3 Query: 460 PVAA-IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRA 284 P+A ++R D+E+ G+ +PKGT + +P+ +H + E W E EF+P RF + Sbjct: 79 PIAGRLERLCKKDVEIHGVSIPKGTTVMVPLFVLHNNPEFWPEP-EEFRPERFSKK-NKD 136 Query: 283 GKHPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVIT 119 G +P L F +GPR+C+G FA++ K + ILQ FSF + K P+ + T Sbjct: 137 GINPYVYLPFGTGPRNCVGMRFALMNIKLALVRILQNFSF-IPCKETQIPLKLYT 190
>C13A6_CAEEL (Q27515) Putative cytochrome P450 CYP13A6 (EC 1.14.-.-)| Length = 518 Score = 80.9 bits (198), Expect = 2e-15 Identities = 40/115 (34%), Positives = 63/115 (54%), Gaps = 3/115 (2%) Frame = -3 Query: 442 RKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGKHPNAL 263 RK + + G+ +G I + T+H + +WGED +FKP R+ENG +H + Sbjct: 394 RKCMRETTINGVNFDEGMNIQVDTWTLHHNPRIWGEDVEDFKPERWENGACEHLEHNGSY 453 Query: 262 LSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVI---TLRPK 107 + F SGPR CIG A +E K ++A IL+ +SF + K P+ ++ TL P+ Sbjct: 454 IPFGSGPRQCIGMRLAQMEQKILLAQILKEYSFR-TTKNTQIPVKLVGKLTLSPE 507
>CP4V3_MOUSE (Q9DBW0) Cytochrome P450 4V3 (EC 1.14.-.-)| Length = 525 Score = 80.5 bits (197), Expect = 2e-15 Identities = 57/130 (43%), Positives = 75/130 (57%), Gaps = 5/130 (3%) Frame = -3 Query: 457 VAAIQRKAGSDLEVGGIKVPKGT-VITIPIATIHRDKEVWGEDANEFKPLRF--ENGVTR 287 V R D EVGG KV KGT I IP A +HRD + D EF+P RF EN Sbjct: 395 VPLFARSLSEDCEVGGYKVTKGTEAIIIPYA-LHRDPRYF-PDPEEFRPERFFPENS--- 449 Query: 286 AGKHPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPM--DVITLR 113 G+HP A + FS+GPR+CIGQ FA++E K ++A IL++F + K + D+I LR Sbjct: 450 QGRHPYAYVPFSAGPRNCIGQKFAVMEEKTILACILRQFWVESNQKREELGLAGDLI-LR 508 Query: 112 PKFGLPMILK 83 P G+ + LK Sbjct: 509 PNNGIWIKLK 518
>CP3AR_ONCMY (O42563) Cytochrome P450 3A27 (EC 1.14.14.1) (CYPIIIA27)| Length = 518 Score = 80.5 bits (197), Expect = 2e-15 Identities = 41/102 (40%), Positives = 60/102 (58%), Gaps = 1/102 (0%) Frame = -3 Query: 460 PVAA-IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRA 284 P+A ++R A +E+ GI +PK ++ +P T+HRD E+W D EFKP RF + Sbjct: 373 PIAPRLERVAKKTVEINGIVIPKDCIVLVPTWTLHRDPEIWS-DPEEFKPERFSKE-NKE 430 Query: 283 GKHPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSL 158 P + F +GPR+CIG FA+I K + ILQ F+FS+ Sbjct: 431 SIDPYTYMPFGAGPRNCIGMRFALIMIKLAMVEILQSFTFSV 472
>C13A5_CAEEL (Q27514) Putative cytochrome P450 CYP13A5 (EC 1.14.-.-)| Length = 520 Score = 80.1 bits (196), Expect = 3e-15 Identities = 42/104 (40%), Positives = 62/104 (59%), Gaps = 2/104 (1%) Frame = -3 Query: 460 PVAAI--QRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTR 287 P+A+I RK + V G+++ KGT + + T+H D +VWGEDANEF+P R+E+G Sbjct: 388 PLASIVHNRKCMKETNVLGVQIEKGTNVQVDTWTLHYDPKVWGEDANEFRPERWESG-DE 446 Query: 286 AGKHPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLS 155 L F GPR CIG AM+E K ++ IL++++F S Sbjct: 447 LFYAKGGYLPFGMGPRICIGMRLAMMEKKMLLTHILKKYTFETS 490
>CP4X1_RAT (Q8K4D6) Cytochrome P450 4X1 (EC 1.14.14.1) (CYPIVX1)| Length = 507 Score = 80.1 bits (196), Expect = 3e-15 Identities = 52/129 (40%), Positives = 68/129 (52%), Gaps = 3/129 (2%) Frame = -3 Query: 460 PVAAIQRKAGSDLEV-GGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRF--ENGVT 290 P+ +I R+ L + G +P G + + I +H + VW +D F PLRF EN Sbjct: 378 PIPSISRELSKPLTLPDGHSLPAGMTVVLSIWGLHHNPAVW-KDPKVFDPLRFTKENSEQ 436 Query: 289 RAGKHPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITLRP 110 R HP A L FSSGPR+CIGQ FAM+E K IA+ L RF + A LRP Sbjct: 437 R---HPCAFLPFSSGPRNCIGQQFAMLELKVAIALTLLRFRVAADLTRPPAFSSHTVLRP 493 Query: 109 KFGLPMILK 83 K G+ + LK Sbjct: 494 KHGIYLHLK 502
>CP3AI_RAT (Q64581) Cytochrome P450 3A18 (EC 1.14.14.1) (CYPIIIA18)| (P450(6)beta-2) Length = 497 Score = 79.3 bits (194), Expect = 4e-15 Identities = 41/99 (41%), Positives = 58/99 (58%), Gaps = 1/99 (1%) Frame = -3 Query: 460 PVAA-IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRA 284 P+A + R + D+E+ G+ +PKGTV+TIPI +HR+ E W E EF P RF + Sbjct: 368 PIATRLDRVSKKDVEINGVFIPKGTVVTIPIYPLHRNPEYWLE-PEEFNPERFSK-ENKG 425 Query: 283 GKHPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFS 167 P L F +GPR+CIG FA+I K + +LQ F+ Sbjct: 426 SIDPYVYLPFGNGPRNCIGMRFALISMKLAVIGVLQNFN 464
>CP134_DROME (Q9VG40) Probable cytochrome P450 313a4 (EC 1.14.-.-)| (CYPCCCXIIIA4) Length = 478 Score = 79.3 bits (194), Expect = 4e-15 Identities = 42/103 (40%), Positives = 59/103 (57%), Gaps = 1/103 (0%) Frame = -3 Query: 460 PVAAIQRKAGSDLEVG-GIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRA 284 PV + R+ DL++ GI VPKG I I I +HR K++WG DA F P F + Sbjct: 349 PVPVVSRQTSQDLKLSNGIVVPKGVQIAIDIYHMHRSKKIWGPDAETFNPDHFLPHNIQ- 407 Query: 283 GKHPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLS 155 KHP A + F+ G R+CIG +A+I AK +A +L+ + F S Sbjct: 408 DKHPYAYIPFTKGIRNCIGWRYALISAKVTLAKLLRNYRFKTS 450
>CP4D2_DROME (Q27589) Cytochrome P450 4d2 (EC 1.14.-.-) (CYPIVD2)| Length = 501 Score = 79.0 bits (193), Expect = 6e-15 Identities = 50/127 (39%), Positives = 76/127 (59%), Gaps = 1/127 (0%) Frame = -3 Query: 460 PVAAIQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAG 281 PV I R D+E+ G +P GT T+ I + RD E + E +EF+P RF+ V + Sbjct: 377 PVPMIGRWFAEDVEIRGKHIPAGTNFTMGIFVLLRDPEYF-ESPDEFRPERFDADVPQI- 434 Query: 280 KHPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFS-FSLSPKYVHAPMDVITLRPKF 104 HP A + FS+GPR+CIGQ FAM+E K+ ++ +L+ F L P+ H+ M+++ LR Sbjct: 435 -HPYAYIPFSAGPRNCIGQKFAMLEMKSTVSKLLRHFELLPLGPEPRHS-MNIV-LRSAN 491 Query: 103 GLPMILK 83 G+ + LK Sbjct: 492 GVHLGLK 498
>CP3AS_BOVIN (P79102) Cytochrome P450 3A28 (EC 1.14.14.1) (CYPIIIA28)| Length = 507 Score = 78.6 bits (192), Expect = 8e-15 Identities = 37/100 (37%), Positives = 59/100 (59%), Gaps = 1/100 (1%) Frame = -3 Query: 460 PVAA-IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRA 284 P+A ++R D+E+ G+ +PKGT + +P+ +H + E+W E EF+P RF + Sbjct: 368 PIAGRLERVCKKDVEIHGVTIPKGTTVLVPLFVLHNNPELWPEP-EEFRPERFSKN-NKD 425 Query: 283 GKHPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSF 164 +P L F +GPR+C+G FA++ K + ILQ FSF Sbjct: 426 SINPYVYLPFGTGPRNCLGMRFAIMNIKLALVRILQNFSF 465
>C356_FUNHE (Q8AXY5) Cytochrome P450 3A56 (EC 1.14.14.1) (CYPIIIA56)| Length = 496 Score = 78.6 bits (192), Expect = 8e-15 Identities = 42/102 (41%), Positives = 61/102 (59%), Gaps = 1/102 (0%) Frame = -3 Query: 460 PVAA-IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRA 284 P+AA ++R A + +E+ GI +PK V+ IP +HRD E+W E FKP RF + Sbjct: 367 PIAARLERVAKAAVEINGIVIPKDMVVMIPTWPLHRDPEIWPEP-EAFKPERFSKK-NKD 424 Query: 283 GKHPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSL 158 P + F SGPR+CIG FA++ K + ILQ++SFS+ Sbjct: 425 NIDPYIYMPFGSGPRNCIGMRFALVLIKLAVVEILQQYSFSV 466
>CP4S3_DROME (Q9VXY0) Probable cytochrome P450 4s3 (EC 1.14.-.-) (CYPIVS3)| Length = 495 Score = 78.6 bits (192), Expect = 8e-15 Identities = 50/119 (42%), Positives = 64/119 (53%) Frame = -3 Query: 457 VAAIQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGK 278 V RK DLEVG + VPKG I+ I +HRD + + D F P RF V Sbjct: 365 VPFFSRKVLEDLEVGKLTVPKGASISCLIYMLHRDPKNF-PDPERFDPDRFL--VNEKQM 421 Query: 277 HPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITLRPKFG 101 HP A +FS+GPR+CIGQ FAM+E K +AM+L+ + F P H P + L K G Sbjct: 422 HPFAFAAFSAGPRNCIGQKFAMLELKTSLAMLLRSYRF--LPDKDHQPKPLAELVTKSG 478
>CP3A9_RAT (P51538) Cytochrome P450 3A9 (EC 1.14.14.1) (CYPIIIA9) (P450-OLF3)| (Olfactive) (3AH15) Length = 503 Score = 78.6 bits (192), Expect = 8e-15 Identities = 39/100 (39%), Positives = 59/100 (59%), Gaps = 1/100 (1%) Frame = -3 Query: 460 PVAA-IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRA 284 P+A ++R +D+E+ G+ +PKGTV+ IP +H+D W E EF+P RF + Sbjct: 368 PIAGRLERVCKTDVEINGVFIPKGTVVMIPTFALHKDPHYWPE-PEEFRPERFSK-KNQD 425 Query: 283 GKHPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSF 164 +P L F +GPR+CIG FA++ K + +LQ FSF Sbjct: 426 NINPYMYLPFGNGPRNCIGMRFALMNMKVALFRVLQNFSF 465
>CP3AD_MOUSE (Q64464) Cytochrome P450 3A13 (EC 1.14.14.1) (CYPIIIA13)| Length = 503 Score = 78.2 bits (191), Expect = 1e-14 Identities = 39/99 (39%), Positives = 59/99 (59%), Gaps = 1/99 (1%) Frame = -3 Query: 460 PVAA-IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRA 284 P+A ++R +D+E+ G+ +PKGTV+ IP +H+D + W E EF+P RF + Sbjct: 368 PIAGRLERVCKTDVEINGLFIPKGTVVMIPTFALHKDPKYWPE-PEEFRPERFSK-KNQD 425 Query: 283 GKHPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFS 167 +P L F SGPR+CIG FA+I K + +LQ F+ Sbjct: 426 SINPYMYLPFGSGPRNCIGMRFALINMKVALVRVLQNFT 464
>C330_FUNHE (Q9PVE8) Cytochrome P450 3A30 (EC 1.14.14.1) (CYPIIIA30)| Length = 496 Score = 78.2 bits (191), Expect = 1e-14 Identities = 41/102 (40%), Positives = 61/102 (59%), Gaps = 1/102 (0%) Frame = -3 Query: 460 PVAA-IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRA 284 P+AA ++R A + +E+ G+ +PK V+ IP +HRD E+W E FKP RF + Sbjct: 367 PIAARLERVAKAAVEINGVVIPKDMVVMIPTWPLHRDPEIWPEP-EAFKPERFSKK-NKD 424 Query: 283 GKHPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSL 158 P + F SGPR+CIG FA++ K + ILQ++SFS+ Sbjct: 425 NIDPYIYMPFGSGPRNCIGMRFALVLIKLAVVEILQQYSFSV 466
>CP3A1_RAT (P04800) Cytochrome P450 3A1 (EC 1.14.14.1) (CYPIIIA1) (P450-PCN1)| Length = 504 Score = 77.0 bits (188), Expect = 2e-14 Identities = 37/95 (38%), Positives = 55/95 (57%) Frame = -3 Query: 448 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGKHPN 269 ++R D+E+ G+ +PKG+V+ IP +HRD + W E EF+P RF + P Sbjct: 374 LERVCKKDVEINGVFMPKGSVVMIPSYALHRDPQHWPEP-EEFRPERFSKE-NKGSIDPY 431 Query: 268 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSF 164 L F +GPR+CIG FA++ K + +LQ FSF Sbjct: 432 VYLPFGNGPRNCIGMRFALMNMKLALTKVLQNFSF 466
>CPXB_BACME (P14779) Bifunctional P-450:NADPH-P450 reductase (Cytochrome| P450(BM-3)) (P450BM-3) [Includes: Cytochrome P450 102 (EC 1.14.14.1); NADPH--cytochrome P450 reductase (EC 1.6.2.4)] Length = 1048 Score = 77.0 bits (188), Expect = 2e-14 Identities = 42/111 (37%), Positives = 62/111 (55%), Gaps = 1/111 (0%) Frame = -3 Query: 436 AGSDLEVGG-IKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGKHPNALL 260 A D +GG + KG + + I +HRDK +WG+D EF+P RFEN + +A Sbjct: 335 AKEDTVLGGEYPLEKGDELMVLIPQLHRDKTIWGDDVEEFRPERFEN---PSAIPQHAFK 391 Query: 259 SFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITLRPK 107 F +G R+CIGQ FA+ EA V+ M+L+ F F Y + +TL+P+ Sbjct: 392 PFGNGQRACIGQQFALHEATLVLGMMLKHFDFEDHTNYELDIKETLTLKPE 442
>C13A3_CAEEL (Q27517) Putative cytochrome P450 CYP13A3 (EC 1.14.-.-)| Length = 520 Score = 76.6 bits (187), Expect = 3e-14 Identities = 44/115 (38%), Positives = 67/115 (58%), Gaps = 2/115 (1%) Frame = -3 Query: 460 PVAAI--QRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTR 287 P+A+I RK V G+K+ +GT + T+H D + WGE+ANEFKP R+E+G + Sbjct: 388 PLASIVHNRKCMKSTTVLGMKIEEGTNVQADTWTLHYDPKFWGENANEFKPERWESGDEQ 447 Query: 286 AGKHPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVI 122 A A L F GPR CIG A +E K ++A IL+++S + + H P+ ++ Sbjct: 448 A-VAKGAYLPFGLGPRICIGMRLAYMEEKMLLAQILKKYSLETTFE-THIPLKLV 500
>CP3AP_MOUSE (O09158) Cytochrome P450 3A25 (EC 1.14.14.1) (CYPIIIA25)| Length = 503 Score = 75.9 bits (185), Expect = 5e-14 Identities = 39/99 (39%), Positives = 58/99 (58%), Gaps = 1/99 (1%) Frame = -3 Query: 460 PVAA-IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRA 284 P+A ++R + D+E+ G+ +PKGTV+ IPI +HR+ E W E EF P RF + Sbjct: 368 PIAIRLERVSKKDVEINGVFIPKGTVVMIPIYPLHRNPEYWPE-PQEFCPERFSK-ENKG 425 Query: 283 GKHPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFS 167 P + F +GPR+CIG FA+I K + +LQ F+ Sbjct: 426 NIDPYIYMPFGNGPRNCIGMRFALISIKLAVIGVLQNFT 464
>CP3AF_CAVPO (Q64406) Cytochrome P450 3A15 (EC 1.14.14.1) (CYPIIIA15)| Length = 503 Score = 75.9 bits (185), Expect = 5e-14 Identities = 39/100 (39%), Positives = 58/100 (58%), Gaps = 1/100 (1%) Frame = -3 Query: 460 PVA-AIQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRA 284 PVA I+R + D E+ G+ PKGT++ IP +HRD + W E +EF+P RF + Sbjct: 368 PVANRIERMSKKDFEINGMSFPKGTLVMIPSFALHRDSKYWPE-PDEFRPERFSK-KNKE 425 Query: 283 GKHPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSF 164 P + F +GPR+CIG+ A++ K + +LQ FSF Sbjct: 426 NIDPYIYMPFGNGPRNCIGRRMALMNLKLALIRLLQNFSF 465
>CP4D1_DROME (P33269) Cytochrome P450 4d1 (EC 1.14.-.-) (CYPIVD1)| Length = 512 Score = 75.5 bits (184), Expect = 6e-14 Identities = 45/128 (35%), Positives = 68/128 (53%) Frame = -3 Query: 457 VAAIQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGK 278 V + RK D E+ G +P GT I I + R +E++ E N FKP RF+ T Sbjct: 383 VPLLGRKVLEDCEINGKLIPAGTNIGISPLYLGRREELFSEP-NSFKPERFDVVTTAEKL 441 Query: 277 HPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITLRPKFGL 98 +P A + FS+GPR+CIGQ FAM+E KA++A +L+ + P+ + L + Sbjct: 442 NPYAYIPFSAGPRNCIGQKFAMLEIKAIVANVLRHYEVDFVGDSSEPPVLIAELILRTKE 501 Query: 97 PMILKSPE 74 P++ K E Sbjct: 502 PLMFKVRE 509
>CP4C3_DROME (Q9VA27) Cytochrome P450 4c3 (EC 1.14.-.-) (CYPIVC3)| Length = 535 Score = 75.5 bits (184), Expect = 6e-14 Identities = 47/123 (38%), Positives = 71/123 (57%), Gaps = 3/123 (2%) Frame = -3 Query: 457 VAAIQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRF--ENGVTRA 284 V + R G D+ +GG VP GT I +HR+ V+ + +F P F EN A Sbjct: 409 VPMMARMVGEDVNIGGKIVPAGTQAIIMTYALHRNPRVFPKP-EQFNPDNFLPENC---A 464 Query: 283 GKHPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSF-SLSPKYVHAPMDVITLRPK 107 G+HP A + FS+GPR+CIGQ FA++E KAVI+ +L+++ ++ + + + LRPK Sbjct: 465 GRHPFAYIPFSAGPRNCIGQKFAILEEKAVISTVLRKYKIEAVDRREDLTLLGELILRPK 524 Query: 106 FGL 98 GL Sbjct: 525 DGL 527
>CP3AG_MOUSE (Q64481) Cytochrome P450 3A16 (EC 1.14.14.1) (CYPIIIA16)| Length = 504 Score = 75.5 bits (184), Expect = 6e-14 Identities = 37/95 (38%), Positives = 53/95 (55%) Frame = -3 Query: 448 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGKHPN 269 +QR D+E+ GI +PKG+ + IP +H D + W E EF+P RF + P Sbjct: 374 LQRVCKKDVEINGIYIPKGSTVIIPSYVLHHDPQHWPEP-EEFQPERFSKE-NKGSIDPY 431 Query: 268 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSF 164 L F +GPR+CIG FA++ K + +LQ FSF Sbjct: 432 VYLPFGNGPRNCIGMRFALMNMKLALIKVLQNFSF 466
>CP4A7_RABIT (P14581) Cytochrome P450 4A7 precursor (EC 1.14.15.3) (CYPIVA7)| (Lauric acid omega-hydroxylase) (P450-KA-2) Length = 511 Score = 75.1 bits (183), Expect = 8e-14 Identities = 46/127 (36%), Positives = 66/127 (51%), Gaps = 1/127 (0%) Frame = -3 Query: 460 PVAAIQRKAGSDLEV-GGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRA 284 PV + K S + G +PKG +IT+ I +H + +VW + F P RF G R Sbjct: 386 PVPGVGSKLSSPVTFPDGRSLPKGIIITLSIYGLHHNPKVW-PNPEVFDPSRFAPGSAR- 443 Query: 283 GKHPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITLRPKF 104 H +A L FS G R+CIG+ FAM E K +A+ L RF P V P+ + L+ K Sbjct: 444 --HSHAFLPFSGGSRNCIGKQFAMNELKVAVALTLVRFELLPDPTRVPIPITRLVLKSKN 501 Query: 103 GLPMILK 83 G+ + L+ Sbjct: 502 GIHLRLR 508
>CP4D1_DROSI (O16805) Cytochrome P450 4d1 (EC 1.14.-.-) (CYPIVD1)| Length = 512 Score = 75.1 bits (183), Expect = 8e-14 Identities = 45/128 (35%), Positives = 68/128 (53%) Frame = -3 Query: 457 VAAIQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGK 278 V + RK D E+ G +P GT I I + R +E++ E N FKP RF+ T Sbjct: 383 VPLLGRKVLEDCEINGKLIPAGTNIGISPLYLGRREELFSEP-NSFKPERFDVVTTAEKL 441 Query: 277 HPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITLRPKFGL 98 +P A + FS+GPR+CIGQ FAM+E KA++A +L+ + P+ + L + Sbjct: 442 NPYAYIPFSAGPRNCIGQKFAMLEIKAIVANVLRHYEVDFVGDSSEPPVLIAELILRTKD 501 Query: 97 PMILKSPE 74 P++ K E Sbjct: 502 PLMFKVRE 509
>C340_ORYLA (Q98T91) Cytochrome P450 3A40 (EC 1.14.14.1)| Length = 502 Score = 74.7 bits (182), Expect = 1e-13 Identities = 39/102 (38%), Positives = 60/102 (58%), Gaps = 1/102 (0%) Frame = -3 Query: 460 PVAA-IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRA 284 P+AA ++R A + +EV G+ +PK V+ +P +HRD E+W E +FKP RF + Sbjct: 369 PIAARLERVAKATVEVNGLVIPKDMVVMVPTWPLHRDPELWPEP-EKFKPERFSKE-NKD 426 Query: 283 GKHPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSL 158 P + F +GPR+CIG FA++ K + ILQ + FS+ Sbjct: 427 TFDPYTYMPFGAGPRNCIGMRFALVMMKLAVVEILQTYDFSV 468
>CP3A2_RAT (P05183) Cytochrome P450 3A2 (EC 1.14.14.1) (CYPIIIA2) (P450-PCN2)| (P450/6-beta-A) (Testosterone 6-beta-hydroxylase) Length = 504 Score = 74.7 bits (182), Expect = 1e-13 Identities = 36/95 (37%), Positives = 54/95 (56%) Frame = -3 Query: 448 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGKHPN 269 ++R D+E+ G+ +PKG+V+TIP +H D + W + EF P RF + P Sbjct: 374 LERVCKKDIELDGLFIPKGSVVTIPTYALHHDPQHWPKP-EEFHPERFSKE-NKGSIDPY 431 Query: 268 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSF 164 L F +GPR+CIG FA++ K + +LQ FSF Sbjct: 432 VYLPFGNGPRNCIGMRFALMNMKLALTKVLQNFSF 466
>C13A7_CAEEL (Q27519) Putative cytochrome P450 CYP13A7 (EC 1.14.-.-)| Length = 518 Score = 74.7 bits (182), Expect = 1e-13 Identities = 40/108 (37%), Positives = 61/108 (56%), Gaps = 2/108 (1%) Frame = -3 Query: 460 PVAAI--QRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTR 287 P+A++ RK V G+++ GT I + ++H D +VWG+D NEFKP R+E+G Sbjct: 388 PLASLVHNRKCLKTTNVLGMEIEAGTNINVDTWSLHHDPKVWGDDVNEFKPERWESG-DE 446 Query: 286 AGKHPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYV 143 L F GPR CIG AM+E K ++ IL+ ++F +P+ V Sbjct: 447 LFFAKGGYLPFGMGPRICIGMRLAMMEMKMLLTNILKNYTFETTPETV 494
>C13A4_CAEEL (Q27513) Putative cytochrome P450 CYP13A4 (EC 1.14.-.-)| Length = 520 Score = 74.3 bits (181), Expect = 1e-13 Identities = 39/104 (37%), Positives = 60/104 (57%), Gaps = 2/104 (1%) Frame = -3 Query: 460 PVAAI--QRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTR 287 P+A++ RK V G+++ +GT + + T+H D +VWG+DA+EFKP R+E G Sbjct: 388 PLASLVHNRKCMKKTNVLGVEIDEGTNVQVDTWTLHYDPKVWGDDASEFKPERWETG-DE 446 Query: 286 AGKHPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLS 155 L F GPR CIG AM+E K ++ IL++++F S Sbjct: 447 LFYAKGGYLPFGMGPRICIGMRLAMMEEKLLLTHILKKYTFDTS 490
>CP4V2_PONPY (Q5RCN6) Cytochrome P450 4V2 (EC 1.14.-.-)| Length = 525 Score = 74.3 bits (181), Expect = 1e-13 Identities = 48/128 (37%), Positives = 69/128 (53%), Gaps = 3/128 (2%) Frame = -3 Query: 457 VAAIQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRF--ENGVTRA 284 V R D EV G +V KGT I +HRD + + EF+P RF EN Sbjct: 395 VPLFARSVSEDCEVAGYRVLKGTEAVIIPYALHRDPRYF-PNPEEFQPERFFPENA---Q 450 Query: 283 GKHPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMD-VITLRPK 107 G+HP A + FS+GPR+CIGQ FA++E K +++ IL+ F + K ++ + LRP Sbjct: 451 GRHPYAYVPFSAGPRNCIGQKFAVMEEKTILSCILRHFWIESNQKREELGLEGQLILRPS 510 Query: 106 FGLPMILK 83 G+ + LK Sbjct: 511 NGIWIKLK 518
>CP4V2_HUMAN (Q6ZWL3) Cytochrome P450 4V2 (EC 1.14.-.-)| Length = 525 Score = 74.3 bits (181), Expect = 1e-13 Identities = 48/128 (37%), Positives = 69/128 (53%), Gaps = 3/128 (2%) Frame = -3 Query: 457 VAAIQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRF--ENGVTRA 284 V R D EV G +V KGT I +HRD + + EF+P RF EN Sbjct: 395 VPLFARSVSEDCEVAGYRVLKGTEAVIIPYALHRDPRYF-PNPEEFQPERFFPENA---Q 450 Query: 283 GKHPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMD-VITLRPK 107 G+HP A + FS+GPR+CIGQ FA++E K +++ IL+ F + K ++ + LRP Sbjct: 451 GRHPYAYVPFSAGPRNCIGQKFAVMEEKTILSCILRHFWIESNQKREELGLEGQLILRPS 510 Query: 106 FGLPMILK 83 G+ + LK Sbjct: 511 NGIWIKLK 518
>CP132_MYCTU (P77900) Putative cytochrome P450 132 (EC 1.14.-.-)| Length = 461 Score = 74.3 bits (181), Expect = 1e-13 Identities = 47/121 (38%), Positives = 68/121 (56%), Gaps = 1/121 (0%) Frame = -3 Query: 448 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGKHPN 269 I R+A D + G ++ +GT + IPI IH D W D + F P RF T + Sbjct: 341 IAREAVDDDIIDGHRIRRGTTVVIPIHHIHHDPR-WWPDPDRFDPGRFLRCPTDRPRC-- 397 Query: 268 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMD-VITLRPKFGLPM 92 A L F G R CIGQ+FA++E + A++ Q F+F L+P Y H ++ +TLRPK G+ + Sbjct: 398 AYLPFGGGRRICIGQSFALMEMVLMAAIMSQHFTFDLAPGY-HVELEATLTLRPKHGVHV 456 Query: 91 I 89 I Sbjct: 457 I 457
>CP132_MYCBO (P59954) Putative cytochrome P450 132 (EC 1.14.-.-)| Length = 461 Score = 74.3 bits (181), Expect = 1e-13 Identities = 47/121 (38%), Positives = 68/121 (56%), Gaps = 1/121 (0%) Frame = -3 Query: 448 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGKHPN 269 I R+A D + G ++ +GT + IPI IH D W D + F P RF T + Sbjct: 341 IAREAVDDDIIDGHRIRRGTTVVIPIHHIHHDPR-WWPDPDRFDPGRFLRCPTDRPRC-- 397 Query: 268 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMD-VITLRPKFGLPM 92 A L F G R CIGQ+FA++E + A++ Q F+F L+P Y H ++ +TLRPK G+ + Sbjct: 398 AYLPFGGGRRICIGQSFALMEMVLMAAIMSQHFTFDLAPGY-HVELEATLTLRPKHGVHV 456 Query: 91 I 89 I Sbjct: 457 I 457
>CP3A5_HUMAN (P20815) Cytochrome P450 3A5 (EC 1.14.14.1) (CYPIIIA5) (P450-PCN3)| (HLp2) Length = 502 Score = 73.9 bits (180), Expect = 2e-13 Identities = 45/130 (34%), Positives = 70/130 (53%), Gaps = 4/130 (3%) Frame = -3 Query: 460 PVAA-IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRA 284 PVA ++R D+E+ G+ +PKG+++ IP +H D + W E EF+P RF + Sbjct: 368 PVAIRLERTCKKDVEINGVFIPKGSMVVIPTYALHHDPKYWTEP-EEFRPERFSK--KKD 424 Query: 283 GKHPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVIT---LR 113 P F +GPR+CIG FA++ K + +LQ FSF K P+ + T L+ Sbjct: 425 SIDPYIYTPFGTGPRNCIGMRFALMNMKLALIRVLQNFSFK-PCKETQIPLKLDTQGLLQ 483 Query: 112 PKFGLPMILK 83 P+ P++LK Sbjct: 484 PE--KPIVLK 491
>CP4A6_RABIT (P14580) Cytochrome P450 4A6 precursor (EC 1.14.15.3) (CYPIVA6)| (Lauric acid omega-hydroxylase) (P450-KA-1) Length = 510 Score = 73.9 bits (180), Expect = 2e-13 Identities = 44/127 (34%), Positives = 65/127 (51%), Gaps = 1/127 (0%) Frame = -3 Query: 460 PVAAIQRKAGSDLEV-GGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRA 284 PV + R+ S + G +PKG ++T+ I +H + +VW + F P F G R Sbjct: 385 PVPGVGRQLSSPVTFPDGRSLPKGVIVTLSIYALHHNPKVW-PNPEVFDPFPFAPGSAR- 442 Query: 283 GKHPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITLRPKF 104 H +A L FS GPR+CIG+ FAM E K +A+ L RF PK V + L+ Sbjct: 443 --HSHAFLPFSGGPRNCIGKQFAMNELKVAVALTLVRFELLPDPKRVPDQKPRLVLKSSN 500 Query: 103 GLPMILK 83 G+ + L+ Sbjct: 501 GIHLRLR 507
>CP3AV_MESAU (O70537) Cytochrome P450 3A31 (EC 1.14.14.1) (CYPIIIA31) (P450| SH3A-1) Length = 501 Score = 73.9 bits (180), Expect = 2e-13 Identities = 44/126 (34%), Positives = 70/126 (55%), Gaps = 4/126 (3%) Frame = -3 Query: 448 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGKHPN 269 ++R D+E+ G+ VPKG+++ +P+ +H D + W E +F+P RF + P Sbjct: 371 LERVCKQDVEMDGVFVPKGSIVMVPVFALHYDPQYWPEP-EKFRPERFSKE-NKGSIDPY 428 Query: 268 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSP-KYVHAPMDV---ITLRPKFG 101 L F +GPR+CIG FA++ K + +LQ +FSL P K PM + L+P+ Sbjct: 429 IFLPFGNGPRNCIGMRFALMNMKLALTKVLQ--NFSLQPCKETQIPMKLSRKAMLQPE-- 484 Query: 100 LPMILK 83 P+ILK Sbjct: 485 KPIILK 490
>C13A8_CAEEL (Q27516) Putative cytochrome P450 CYP13A8 (EC 1.14.-.-)| Length = 509 Score = 73.6 bits (179), Expect = 2e-13 Identities = 41/118 (34%), Positives = 66/118 (55%), Gaps = 3/118 (2%) Frame = -3 Query: 451 AIQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGKHP 272 A R+ + +G V G + I T+H DK VWG D EFKP R+++ +T Sbjct: 387 ANSRRCMRNTVIGEQIVEAGVDVMIDTWTLHHDKNVWGNDVEEFKPERWDSPLTPQ---- 442 Query: 271 NALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVI---TLRPK 107 A LSF +GPR C+G FA++E K +++ IL++++F + K P+ ++ T RP+ Sbjct: 443 QAYLSFGAGPRVCLGMRFALLEQKGLLSHILKKYTFETNAK-TQLPIKLVGRATARPE 499
>CP3AB_MOUSE (Q64459) Cytochrome P450 3A11 (EC 1.14.14.1) (CYPIIIA11)| (P-450IIIAM1) (P-450UT) Length = 504 Score = 73.6 bits (179), Expect = 2e-13 Identities = 36/100 (36%), Positives = 56/100 (56%), Gaps = 1/100 (1%) Frame = -3 Query: 460 PVA-AIQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRA 284 P+A ++R D+E+ G+ +PKG+ + IP +H D + W E EF+P RF + Sbjct: 369 PIANRLERVCKKDVELNGVYIPKGSTVMIPSYALHHDPQHWSEP-EEFQPERFSKE-NKG 426 Query: 283 GKHPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSF 164 P L F +GPR+C+G FA++ K + I+Q FSF Sbjct: 427 SIDPYVYLPFGNGPRNCLGMRFALMNMKLALTKIMQNFSF 466
>CP3AH_CAVPO (Q64409) Cytochrome P450 3A17 (EC 1.14.14.1) (CYPIIIA17)| Length = 503 Score = 73.6 bits (179), Expect = 2e-13 Identities = 44/125 (35%), Positives = 67/125 (53%), Gaps = 3/125 (2%) Frame = -3 Query: 448 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGKHPN 269 I+R + D E+ G+ PKGT + IP +HRD + W E +EF+P RF + P Sbjct: 373 IERMSKKDFEINGMSFPKGTGVMIPSFALHRDSKYWPE-PDEFRPERFSK-KNKENIDPY 430 Query: 268 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDV---ITLRPKFGL 98 + F +GPR+CIG A++ K + +LQ FSF + K P+ + + L+P Sbjct: 431 IYMPFGNGPRNCIGMRMALMNLKLALIRLLQNFSF-YTCKETQIPLRLGSQVILQP--AK 487 Query: 97 PMILK 83 P+ILK Sbjct: 488 PIILK 492
>CP3A6_RABIT (P11707) Cytochrome P450 3A6 (EC 1.14.14.1) (CYPIIIA6) (P450-3C)| Length = 501 Score = 73.2 bits (178), Expect = 3e-13 Identities = 35/102 (34%), Positives = 59/102 (57%), Gaps = 1/102 (0%) Frame = -3 Query: 460 PVAA-IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRA 284 P+A ++R D+++ G +PKGT++ +P +HRD + W E +EF+P RF + Sbjct: 366 PIAGRLERVCKKDVDINGTFIPKGTIVMMPTYALHRDPQHWTEP-DEFRPERFSKK-NKD 423 Query: 283 GKHPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSL 158 +P F +GPR+C+G FA++ K + ++Q FSF L Sbjct: 424 NINPYIYHPFGAGPRNCLGMRFALMNIKLALVRLMQNFSFKL 465
>CP131_DROME (Q9VFJ0) Probable cytochrome P450 313a1 (EC 1.14.-.-)| (CYPCCCXIIIA1) Length = 492 Score = 73.2 bits (178), Expect = 3e-13 Identities = 42/107 (39%), Positives = 58/107 (54%), Gaps = 2/107 (1%) Frame = -3 Query: 460 PVAAIQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRF--ENGVTR 287 P+ A + K L G+ +PKG VI I + HR+ EVWG DA+ F P F EN Sbjct: 365 PITARETKNDVRLS-NGVLIPKGVVIGIDMFHTHRNPEVWGPDADNFNPDNFLAEN---M 420 Query: 286 AGKHPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKY 146 KHP A + F+ G R+CIG +AM+ +K + IL+ + S S Y Sbjct: 421 EQKHPYAYIPFARGKRNCIGSKYAMMSSKFALCRILRNYKISTSTLY 467
>CP3AE_CAVPO (Q64417) Cytochrome P450 3A14 (EC 1.14.14.1) (CYPIIIA14)| Length = 503 Score = 73.2 bits (178), Expect = 3e-13 Identities = 36/95 (37%), Positives = 53/95 (55%) Frame = -3 Query: 448 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGKHPN 269 I+R + D E+ G+ PKGT + IP +HRD + W E +EF+P RF + P Sbjct: 373 IERMSKKDFEINGMSFPKGTGVMIPSFALHRDSKYWPE-PDEFRPERFSK-KNKENIDPY 430 Query: 268 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSF 164 + F +GPR+CIG A++ K + +LQ FSF Sbjct: 431 IYMPFGNGPRNCIGMRMALMNLKLALIRLLQNFSF 465
>CP4A2_RAT (P20816) Cytochrome P450 4A2 precursor (EC 1.14.15.3) (CYPIVA2)| (Lauric acid omega-hydroxylase) (P450-LA-omega 2) (P450 K-5) (P-450 K-2) Length = 504 Score = 72.4 bits (176), Expect = 5e-13 Identities = 45/127 (35%), Positives = 64/127 (50%), Gaps = 1/127 (0%) Frame = -3 Query: 460 PVAAIQRKAGSDLEV-GGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRA 284 PV ++ R+ S + G +PKG +TI I +H + W + F P RF R Sbjct: 379 PVPSVSRELSSPVTFPDGRSIPKGIRVTILIYGLHHNPSYW-PNPKVFDPSRFSPDSPR- 436 Query: 283 GKHPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITLRPKF 104 H +A L FS G R+CIG+ FAM E K +A+ L RF P + PM + L+ K Sbjct: 437 --HSHAYLPFSGGARNCIGKQFAMNELKVAVALTLLRFELLPDPTRIPVPMPRLVLKSKN 494 Query: 103 GLPMILK 83 G+ + LK Sbjct: 495 GIHLRLK 501
>C13A1_CAEEL (Q27520) Putative cytochrome P450 CYP13A1 (EC 1.14.-.-)| Length = 519 Score = 72.4 bits (176), Expect = 5e-13 Identities = 34/101 (33%), Positives = 56/101 (55%) Frame = -3 Query: 451 AIQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGKHP 272 A R+ + ++G +KV GT+I + T+H D +WG+DA +FKP R++ + Sbjct: 393 ANSRRCMRNTKLGNMKVEVGTMIQVDTWTLHTDPNIWGDDAEDFKPERWQTPNSDQIYQK 452 Query: 271 NALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPK 149 + + F GPR CIG A +E K ++ IL++F+F K Sbjct: 453 SGYIPFGLGPRQCIGMRLAYMEEKILLVHILRKFTFETGAK 493
>CP4AA_RAT (P08516) Cytochrome P450 4A10 (EC 1.14.15.3) (CYPIVA10) (Lauric| acid omega-hydroxylase) (P450-LA-omega 1) (P452) Length = 509 Score = 72.4 bits (176), Expect = 5e-13 Identities = 44/127 (34%), Positives = 66/127 (51%), Gaps = 1/127 (0%) Frame = -3 Query: 460 PVAAIQRKAGSDLEV-GGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRA 284 PV I R+ + + G +PKG +T+ I +H + +VW + F P RF R Sbjct: 384 PVPGIVRELSTSVTFPDGRSLPKGIQVTLSIYGLHHNPKVW-PNPEVFDPSRFAPDSPR- 441 Query: 283 GKHPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITLRPKF 104 H ++ L FS G R+CIG+ FAM E K ++A+ L RF P V P+ + L+ K Sbjct: 442 --HSHSFLPFSGGARNCIGKQFAMSEMKVIVALTLLRFELLPDPTKVPIPLPRLVLKSKN 499 Query: 103 GLPMILK 83 G+ + LK Sbjct: 500 GIYLYLK 506
>CP4AA_MOUSE (O88833) Cytochrome P450 4A10 (EC 1.14.15.3) (CYPIVA10) (Lauric| acid omega-hydroxylase) (P450-LA-omega 1) (P452) Length = 509 Score = 71.6 bits (174), Expect = 9e-13 Identities = 44/127 (34%), Positives = 66/127 (51%), Gaps = 1/127 (0%) Frame = -3 Query: 460 PVAAIQRKAGSDLEV-GGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRA 284 PV I R+ + + G +PKG +T+ I +H + +VW + F P RF R Sbjct: 384 PVPGIVRELSTSVTFPDGRSLPKGVQVTLSIYGLHHNPKVW-PNPEVFDPSRFAPDSPR- 441 Query: 283 GKHPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITLRPKF 104 H ++ L FS G R+CIG+ FAM E K ++A+ L RF P V P+ + L+ K Sbjct: 442 --HSHSFLPFSGGARNCIGKQFAMSELKVIVALTLLRFELLPDPTRVPMPLARLVLKSKN 499 Query: 103 GLPMILK 83 G+ + LK Sbjct: 500 GIYLHLK 506
>CP4AE_RAT (P20817) Cytochrome P450 4A14 precursor (EC 1.14.15.3) (CYPIVA14)| (Lauric acid omega-hydroxylase) (P450-LA-omega 3) Length = 507 Score = 71.6 bits (174), Expect = 9e-13 Identities = 45/127 (35%), Positives = 63/127 (49%), Gaps = 1/127 (0%) Frame = -3 Query: 460 PVAAIQRKAGSDLEV-GGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRA 284 PV ++ R+ S + G +PKG TI I +H + W + F P RF R Sbjct: 382 PVPSVSRELSSPVTFPDGRSIPKGITTTILIYGLHHNPSYW-PNPKVFDPSRFSPDSPR- 439 Query: 283 GKHPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITLRPKF 104 H +A L FS G R+CIG+ FAM E K +A+ L RF P + PM + L+ K Sbjct: 440 --HSHAYLPFSGGARNCIGKQFAMNELKVAVALTLLRFELLPDPTRIPVPMARLVLKSKN 497 Query: 103 GLPMILK 83 G+ + LK Sbjct: 498 GIHLRLK 504
>CP4CU_BLAGE (Q964T1) Cytochrome P450 4c21 (EC 1.14.14.1) (CYPIVC21)| Length = 501 Score = 71.6 bits (174), Expect = 9e-13 Identities = 37/97 (38%), Positives = 57/97 (58%), Gaps = 4/97 (4%) Frame = -3 Query: 442 RKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGE----DANEFKPLRFENGVTRAGKH 275 R+A D E+GG +P GT I + IHR+ E++ + + F P R N +H Sbjct: 380 REAHQDFELGGYTIPAGTNIDFSVPFIHRNPEIFPNPRCFNPDNFLPDRVVN------RH 433 Query: 274 PNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSF 164 P A + FS+GPR+CIGQ FA++E K V++ +L+ + F Sbjct: 434 PYAYIPFSAGPRNCIGQRFALLEEKVVLSYLLRHYRF 470
>C13A2_CAEEL (Q27518) Putative cytochrome P450 CYP13A2 (EC 1.14.-.-)| Length = 515 Score = 71.6 bits (174), Expect = 9e-13 Identities = 37/106 (34%), Positives = 56/106 (52%), Gaps = 2/106 (1%) Frame = -3 Query: 460 PVAAIQ--RKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTR 287 P+A+I RK V G+K+ G + + ++H D E+WGED EFKP R+ Sbjct: 385 PLASISNSRKCMKTTTVNGVKIEAGVYVQMDTWSLHYDPELWGEDVKEFKPERW--STDE 442 Query: 286 AGKHPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPK 149 +H A L F GPR CIG A++E K ++ +L+ ++F K Sbjct: 443 PLEHKGAYLPFGLGPRQCIGMRLAIMEQKILLTHLLKNYTFETGNK 488
>CP3A7_HUMAN (P24462) Cytochrome P450 3A7 (EC 1.14.14.1) (CYPIIIA7) (P450-HFLA)| Length = 503 Score = 71.6 bits (174), Expect = 9e-13 Identities = 38/100 (38%), Positives = 54/100 (54%), Gaps = 1/100 (1%) Frame = -3 Query: 460 PVAA-IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRA 284 PVA ++R D+E+ G+ +PKG V+ IP +H D + W E +F P RF + Sbjct: 368 PVAMRLERVCKKDVEINGMFIPKGVVVMIPSYVLHHDPKYWREP-EKFLPERFSKK-NKD 425 Query: 283 GKHPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSF 164 P F SGPR+CIG FA++ K + +LQ FSF Sbjct: 426 NIDPYIYTPFGSGPRNCIGMRFALVNMKLALVRVLQNFSF 465
>CP3A8_MACFA (P33268) Cytochrome P450 3A8 (EC 1.14.14.1) (CYPIIIA8) (P450-MKNF2)| (P-450-MK2) Length = 503 Score = 71.2 bits (173), Expect = 1e-12 Identities = 39/100 (39%), Positives = 53/100 (53%), Gaps = 1/100 (1%) Frame = -3 Query: 460 PVAA-IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRA 284 P+A ++R D+E+ GI +PKG V+ IP +H D + W E +F P RF Sbjct: 368 PIAMRLERVCKKDVEINGIFIPKGVVVMIPSYALHHDPKYWPEP-EKFLPERFSKK-NND 425 Query: 283 GKHPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSF 164 P F SGPR+CIG FA++ K I +LQ FSF Sbjct: 426 NIDPYIYTPFGSGPRNCIGMRFALMNMKLAIIRVLQNFSF 465
>CP3A3_HUMAN (P05184) Cytochrome P450 3A3 (EC 1.14.14.1) (CYPIIIA3) (HLp)| Length = 503 Score = 71.2 bits (173), Expect = 1e-12 Identities = 38/100 (38%), Positives = 55/100 (55%), Gaps = 1/100 (1%) Frame = -3 Query: 460 PVAA-IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRA 284 P+A ++R D+E+ G+ +PKG V+ IP +HRD + W E +F P RF + Sbjct: 368 PIAMRLERVCKKDVEINGMFIPKGWVVMIPSYALHRDPKYWTEP-EKFLPERFSKK-NKD 425 Query: 283 GKHPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSF 164 P F SGPR+CIG FA++ K + +LQ FSF Sbjct: 426 NIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSF 465
>CP4A5_RABIT (P14579) Cytochrome P450 4A5 precursor (EC 1.14.15.3) (CYPIVA5)| (Lauric acid omega-hydroxylase) Length = 511 Score = 71.2 bits (173), Expect = 1e-12 Identities = 45/127 (35%), Positives = 63/127 (49%), Gaps = 1/127 (0%) Frame = -3 Query: 460 PVAAIQRKAGSDLEV-GGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRA 284 PV AI R S + G +PKG +T+ I +H + VW + F P RF G R Sbjct: 386 PVPAISRDLSSPVTFPDGRSLPKGFTVTLSIYGLHHNPNVW-PNPEVFDPGRFTPGSAR- 443 Query: 283 GKHPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITLRPKF 104 H +A L FS G R+CIG+ FAM E K +A+ L RF P + P + L+ Sbjct: 444 --HSHAFLPFSGGARNCIGKQFAMNELKVAVALTLVRFELLPDPTRIPKPTARLVLKSNN 501 Query: 103 GLPMILK 83 G+ + L+ Sbjct: 502 GIHLRLR 508
>THAS_MOUSE (P36423) Thromboxane-A synthase (EC 5.3.99.5) (TXA synthase) (TXS)| (TS) Length = 533 Score = 71.2 bits (173), Expect = 1e-12 Identities = 37/104 (35%), Positives = 52/104 (50%) Frame = -3 Query: 460 PVAAIQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAG 281 P R+A D EV G ++P GTV+ I + +H D E W + F P RF R Sbjct: 406 PAFRFTREAAQDCEVLGQRIPAGTVLEIAVGALHHDPEHW-PNPETFDPERF-TAEARLQ 463 Query: 280 KHPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPK 149 + P L F +GPRSC+G ++ K I +L +F F SP+ Sbjct: 464 RRPFTYLPFGAGPRSCLGVRLGLLVVKLTILQVLHKFRFEASPE 507
>CP3A4_HUMAN (P08684) Cytochrome P450 3A4 (EC 1.14.13.67) (Quinine| 3-monooxygenase) (CYPIIIA4) (Nifedipine oxidase) (Taurochenodeoxycholate 6-alpha-hydroxylase) (EC 1.14.13.97) (NF-25) (P450-PCN1) Length = 502 Score = 71.2 bits (173), Expect = 1e-12 Identities = 38/100 (38%), Positives = 55/100 (55%), Gaps = 1/100 (1%) Frame = -3 Query: 460 PVAA-IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRA 284 P+A ++R D+E+ G+ +PKG V+ IP +HRD + W E +F P RF + Sbjct: 367 PIAMRLERVCKKDVEINGMFIPKGWVVMIPSYALHRDPKYWTEP-EKFLPERFSKK-NKD 424 Query: 283 GKHPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSF 164 P F SGPR+CIG FA++ K + +LQ FSF Sbjct: 425 NIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSF 464
>CP4AC_MOUSE (Q91WL5) Cytochrome P450 4A12 (EC 1.14.14.1) (CYPIVA12)| Length = 508 Score = 70.9 bits (172), Expect = 2e-12 Identities = 44/127 (34%), Positives = 65/127 (51%), Gaps = 1/127 (0%) Frame = -3 Query: 460 PVAAIQRKAGSDLEV-GGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRA 284 PV ++ R+ S + G +PKG + + +H + VW + F P RF G +R Sbjct: 383 PVPSVSRELSSPVTFPDGRSLPKGIHVMLSFYGLHHNPTVW-PNPEVFDPSRFAPGSSR- 440 Query: 283 GKHPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITLRPKF 104 H ++ L FS G R+CIG+ FAM E K +A+ L RF P V P+ I L+ K Sbjct: 441 --HSHSFLPFSGGARNCIGKQFAMNELKVAVALTLLRFELLPDPTRVPIPIPRIVLKSKN 498 Query: 103 GLPMILK 83 G+ + LK Sbjct: 499 GIHLHLK 505
>CP4AE_MOUSE (O35728) Cytochrome P450 4A14 precursor (EC 1.14.15.3) (CYPIVA14)| (Lauric acid omega-hydroxylase 3) (P450-LA-omega 3) Length = 507 Score = 70.9 bits (172), Expect = 2e-12 Identities = 43/127 (33%), Positives = 63/127 (49%), Gaps = 1/127 (0%) Frame = -3 Query: 460 PVAAIQRKAGSDLEV-GGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRA 284 PV ++ R+ S + G +PKG TI I +H + W + F P RF + Sbjct: 382 PVISVSRELSSPVTFPDGRSIPKGITATISIYGLHHNPRFW-PNPKVFDPSRF---APDS 437 Query: 283 GKHPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITLRPKF 104 H +A L FS G R+CIG+ FAM E K +A+ L RF P + P+ + L+ K Sbjct: 438 SHHSHAYLPFSGGSRNCIGKQFAMNELKVAVALTLLRFELLPDPTRIPVPIARLVLKSKN 497 Query: 103 GLPMILK 83 G+ + LK Sbjct: 498 GIHLCLK 504
>C4D10_DROMT (O18596) Cytochrome P450 4d10 (EC 1.14.-.-) (CYPIVD10)| Length = 513 Score = 70.9 bits (172), Expect = 2e-12 Identities = 41/125 (32%), Positives = 67/125 (53%) Frame = -3 Query: 457 VAAIQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGK 278 V + RK + E+ G +P GT I I + R +++ E N FKP RF+ + Sbjct: 384 VPLLGRKVLQECEINGKIIPAGTNIGISPLFLGRSEDISSEP-NTFKPERFDVVTSAEKL 442 Query: 277 HPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITLRPKFGL 98 +P+A + FS+GPR+CIGQ FAM+E KA+ A +L+ + +P+ + L + Sbjct: 443 NPHAYIPFSAGPRNCIGQKFAMLEIKAIAANVLRHYEIEFVGNAEESPVLIAELILRTKD 502 Query: 97 PMILK 83 P++ K Sbjct: 503 PLMFK 507
>CP4X1_HUMAN (Q8N118) Cytochrome P450 4X1 (EC 1.14.14.1) (CYPIVX1)| Length = 509 Score = 70.5 bits (171), Expect = 2e-12 Identities = 45/112 (40%), Positives = 60/112 (53%), Gaps = 2/112 (1%) Frame = -3 Query: 412 GIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRF--ENGVTRAGKHPNALLSFSSGPR 239 G +P G + + I +H + VW ++ F PLRF EN R HP A L FS+G R Sbjct: 397 GCTLPAGITVVLSIWGLHHNPAVW-KNPKVFDPLRFSQENSDQR---HPYAYLPFSAGSR 452 Query: 238 SCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITLRPKFGLPMILK 83 +CIGQ FAMIE K IA+IL F + P + L+PK G+ + LK Sbjct: 453 NCIGQEFAMIELKVTIALILLHFRVTPDPTRPLTFPNHFILKPKNGMYLHLK 504
>CP3AA_MESAU (Q64148) Cytochrome P450 3A10 (EC 1.14.13.94) (CYPIIIA10)| (Lithocholate 6-beta-hydroxylase) (6 beta-hydroxylase) Length = 503 Score = 70.5 bits (171), Expect = 2e-12 Identities = 34/99 (34%), Positives = 55/99 (55%), Gaps = 1/99 (1%) Frame = -3 Query: 460 PVA-AIQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRA 284 P+A ++R + +E+ G+ +PKG + +P +HRD E W E EF+P RF + Sbjct: 368 PIANRLERISKKAVEINGLFIPKGITVMVPTYPLHRDPEYWPEP-EEFRPERFSKE-NKG 425 Query: 283 GKHPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFS 167 P + F +GPR+CIG FA++ K + +LQ F+ Sbjct: 426 SIDPYVYMPFGNGPRNCIGMRFALLSMKLAVVSVLQNFT 464
>CP4F5_RAT (P51870) Cytochrome P450 4F5 (EC 1.14.14.1) (CYPIVF5)| Length = 526 Score = 70.1 bits (170), Expect = 3e-12 Identities = 45/122 (36%), Positives = 64/122 (52%), Gaps = 1/122 (0%) Frame = -3 Query: 460 PVAAIQRKAGSDLEV-GGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRA 284 P + R+ D+ + G +PKG + I I IH + VW D F P RF++ R Sbjct: 396 PAIDLLRRCTQDIVLPDGRVIPKGNICVISIFGIHHNPSVW-PDPEVFDPFRFDSE-NRQ 453 Query: 283 GKHPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITLRPKF 104 + P + + FS+GPR+CIGQ FAM E K V+A+ L RF K ++I LR + Sbjct: 454 KRSPLSFIPFSAGPRNCIGQTFAMNEMKVVVALTLLRFRVLPDDKEPRRKPEII-LRAEG 512 Query: 103 GL 98 GL Sbjct: 513 GL 514
>C13AA_CAEEL (Q09653) Putative cytochrome P450 CYP13A10 (EC 1.14.-.-)| Length = 519 Score = 70.1 bits (170), Expect = 3e-12 Identities = 32/101 (31%), Positives = 57/101 (56%) Frame = -3 Query: 451 AIQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGKHP 272 A R+ ++G ++V GT++ + ++H D ++WG+DA EFKP R+ + Sbjct: 393 ANSRRCMRATKLGNVEVEVGTMVQVDTWSLHTDTKIWGDDAKEFKPERWLDPNCDQVFQK 452 Query: 271 NALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPK 149 +SF GPR C+G A +E K ++A IL++++F + K Sbjct: 453 GGYISFGLGPRQCVGMRLAYMEEKMLLAHILRKYTFEVGTK 493
>CP4AB_HUMAN (Q02928) Cytochrome P450 4A11 precursor (EC 1.14.15.3) (CYPIVA11)| (Fatty acid omega-hydroxylase) (P-450 HK omega) (Lauric acid omega-hydroxylase) (CYP4AII) (P450-HL-omega) Length = 519 Score = 69.7 bits (169), Expect = 3e-12 Identities = 42/127 (33%), Positives = 66/127 (51%), Gaps = 1/127 (0%) Frame = -3 Query: 460 PVAAIQRKAGSDLEV-GGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRA 284 PV I R+ + + G +PKG ++ + I +H + +VW + F P RF G + Sbjct: 385 PVPGIGRELSTPVTFPDGRSLPKGIMVLLSIYGLHHNPKVW-PNPEVFDPFRFAPG---S 440 Query: 283 GKHPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITLRPKF 104 +H +A L FS G R+CIG+ FAM E K A+ L RF P + P+ + L+ K Sbjct: 441 AQHSHAFLPFSGGSRNCIGKQFAMNELKVATALTLLRFELLPDPTRIPIPIARLVLKSKN 500 Query: 103 GLPMILK 83 G+ + L+ Sbjct: 501 GIHLRLR 507
>C13B1_CAEEL (O17624) Putative cytochrome P450 cyp-13B1 (EC 1.14.-.-)| Length = 527 Score = 69.3 bits (168), Expect = 5e-12 Identities = 34/99 (34%), Positives = 56/99 (56%), Gaps = 2/99 (2%) Frame = -3 Query: 460 PVA--AIQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTR 287 PVA A R+ +G I + KG I + ++HR KE+WGE+A++F P E + Sbjct: 382 PVAWFACSRECVKPTTLGDIYIDKGVKIEADVMSLHRSKEIWGENADDFVP---ERWLEP 438 Query: 286 AGKHPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRF 170 + +H + + F +GPR C+G + EAK +A +L+R+ Sbjct: 439 SSRHTMSWIPFGAGPRQCVGMRLGLSEAKTALAHLLRRY 477
>CP52J_CANMA (Q12588) Cytochrome P450 52A10 (EC 1.14.14.-) (CYPLIIA10)| (Alkane-inducible P450-ALK7) Length = 519 Score = 69.3 bits (168), Expect = 5e-12 Identities = 39/94 (41%), Positives = 57/94 (60%), Gaps = 2/94 (2%) Frame = -3 Query: 409 IKVPKGTVITIPIATIHRDKEVWGEDANEFKPLR-FENGVTRAGKHPNALLSFSSGPRSC 233 I V KG + + + RD++ +G+DANEF+P R FE V + G A L F+ GPR C Sbjct: 410 ILVRKGQTVMYSVYALQRDEKYYGKDANEFRPERWFEPEVRKLGW---AFLPFNGGPRIC 466 Query: 232 IGQNFAMIEAKAVIAMILQRF-SFSLSPKYVHAP 134 +GQ FA+ EA V+A ++Q F + LSP+ + P Sbjct: 467 LGQQFALTEASYVLARLIQSFETLELSPEAAYPP 500
>CP3AL_CALJA (O18993) Cytochrome P450 3A21 (EC 1.14.14.1) (CYPIIIA21) (P450| CM3A-10) Length = 503 Score = 69.3 bits (168), Expect = 5e-12 Identities = 34/95 (35%), Positives = 51/95 (53%) Frame = -3 Query: 448 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGKHPN 269 ++R D+E+ G+ +PKG V+ IP +H D + W E +F P RF + P Sbjct: 373 LERVCKKDVEINGVFIPKGVVVMIPSYALHYDPKYWTEP-EKFLPERFSKN-NKDNIDPY 430 Query: 268 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSF 164 F +GPR+CIG FA++ K + +LQ FSF Sbjct: 431 IYTPFGTGPRNCIGMRFALMNMKLALIRVLQNFSF 465
>CP4A4_RABIT (P10611) Cytochrome P450 4A4 precursor (EC 1.14.14.1) (CYPIVA4)| (Prostaglandin omega-hydroxylase) (P450-P-2) Length = 510 Score = 68.9 bits (167), Expect = 6e-12 Identities = 40/127 (31%), Positives = 66/127 (51%), Gaps = 1/127 (0%) Frame = -3 Query: 460 PVAAIQRKAGSDLEV-GGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRA 284 PV ++ R+ + G +PKG ++ + I +H + +VW ++ F P RF + Sbjct: 385 PVPSVTRQLSKPVTFPDGRSLPKGVILFLSIYGLHYNPKVW-QNPEVFDPFRF---APDS 440 Query: 283 GKHPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITLRPKF 104 H +A L FS G R+CIG+ FAM E K +A+ L RF P + P+ + L+ K Sbjct: 441 AYHSHAFLPFSGGARNCIGKQFAMRELKVAVALTLVRFELLPDPTRIPIPIARVVLKSKN 500 Query: 103 GLPMILK 83 G+ + L+ Sbjct: 501 GIHLRLR 507
>CP341_MOUSE (Q9JMA7) Cytochrome P450 3A41 (EC 1.14.14.1)| Length = 504 Score = 68.9 bits (167), Expect = 6e-12 Identities = 33/95 (34%), Positives = 51/95 (53%) Frame = -3 Query: 448 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGKHPN 269 ++R D+E+ G+ +PKG+ + IP +H D + W E EF+P RF + P Sbjct: 374 LERFCKKDVELNGVYIPKGSTVMIPSYALHHDPQHWPEP-EEFQPERFSKE-NKGSIDPY 431 Query: 268 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSF 164 + F GPR+CIG FA + K + ++Q FSF Sbjct: 432 LYMPFGIGPRNCIGMRFAFMTMKLALTKVMQNFSF 466
>CP4AC_RAT (P24464) Cytochrome P450 4A12 (EC 1.14.14.1) (CYPIVA12) (CYPIVA8)| (P450-KP1) (P450-PP1) Length = 508 Score = 68.6 bits (166), Expect = 8e-12 Identities = 40/127 (31%), Positives = 63/127 (49%), Gaps = 1/127 (0%) Frame = -3 Query: 460 PVAAIQRKAGSDLEV-GGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRA 284 PV A+ R + + G +PKG + + +H + VW + F P RF + Sbjct: 383 PVTAVSRMLSTPVTFPDGRSLPKGITVMLSFYGLHHNPTVW-PNPEVFDPYRF---APES 438 Query: 283 GKHPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITLRPKF 104 +H ++ L FS G R+CIG+ FAM E K +A+ L RF P + P+ + L+ K Sbjct: 439 SRHSHSFLPFSGGARNCIGKQFAMNELKVAVALTLLRFELLPDPTRIPIPIPRLVLKSKN 498 Query: 103 GLPMILK 83 G+ + LK Sbjct: 499 GIYLRLK 505
>CP4Z1_HUMAN (Q86W10) Cytochrome P450 4Z1 (EC 1.14.14.1) (CYPIVZ1)| Length = 505 Score = 68.2 bits (165), Expect = 1e-11 Identities = 42/112 (37%), Positives = 60/112 (53%), Gaps = 2/112 (1%) Frame = -3 Query: 412 GIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGKHPNALLSFSSGPRSC 233 G +P G + I I +H + W ED F PLRF + HP A + FS+G R+C Sbjct: 395 GRSLPAGITVFINIWALHHNPYFW-EDPQVFNPLRFSRENSEK-IHPYAFIPFSAGLRNC 452 Query: 232 IGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDV--ITLRPKFGLPMILK 83 IGQ+FA+IE K +A+ L R F L+P + P V + L+ K G+ + K Sbjct: 453 IGQHFAIIECKVAVALTLLR--FKLAPDHSRPPQPVRQVVLKSKNGIHVFAK 502
>CYPE_BACSU (O08336) Probable bifunctional P-450:NADPH-P450 reductase 2| [Includes: Cytochrome P450 102 (EC 1.14.14.1); NADPH--cytochrome P450 reductase (EC 1.6.2.4)] Length = 1054 Score = 68.2 bits (165), Expect = 1e-11 Identities = 37/110 (33%), Positives = 59/110 (53%), Gaps = 1/110 (0%) Frame = -3 Query: 436 AGSDLEVGG-IKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGKHPNALL 260 A D +GG + KG +T+ I +HRD+ WG DA +F+P RFE+ + +A Sbjct: 338 AKEDTVLGGEYPISKGQPVTVLIPKLHRDQNAWGPDAEDFRPERFED---PSSIPHHAYK 394 Query: 259 SFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITLRP 110 F +G R+CIG FA+ EA V+ ++L+ F Y + +T++P Sbjct: 395 PFGNGQRACIGMQFALQEATMVLGLVLKHFELINHTGYELKIKEALTIKP 444
>CP4F8_HUMAN (P98187) Cytochrome P450 4F8 (EC 1.14.14.1) (CYPIVF8)| Length = 520 Score = 67.8 bits (164), Expect = 1e-11 Identities = 42/100 (42%), Positives = 54/100 (54%), Gaps = 3/100 (3%) Frame = -3 Query: 460 PVAAIQRKAGSDLEVGGIKV-PKGTVITIPIATIHRDKEVWGEDANEFKPLRF--ENGVT 290 P+ R D+ + +V PKG V I I IH + VW D + P RF EN Sbjct: 394 PIPTFARGCTQDVVLPDSRVIPKGNVCNINIFAIHHNPSVW-PDPEVYDPFRFDPENAQK 452 Query: 289 RAGKHPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRF 170 R+ P A + FS+GPR+CIGQ FAM E K V+A+ L RF Sbjct: 453 RS---PMAFIPFSAGPRNCIGQKFAMAEMKVVLALTLLRF 489
>CP4FC_HUMAN (Q9HCS2) Cytochrome P450 4F12 (EC 1.14.14.1) (CYPIVF12)| Length = 524 Score = 67.4 bits (163), Expect = 2e-11 Identities = 39/100 (39%), Positives = 55/100 (55%), Gaps = 1/100 (1%) Frame = -3 Query: 460 PVAAIQRKAGSDLEV-GGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRA 284 P I R D+ + G +PKG I I +H + VW D + P RF+ ++ Sbjct: 394 PAPFISRCCTQDIVLPDGRVIPKGITCLIDIIGVHHNPTVW-PDPEVYDPFRFDPENSK- 451 Query: 283 GKHPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSF 164 G+ P A + FS+GPR+CIGQ FAM E K V+A++L F F Sbjct: 452 GRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRF 491
>CP4F6_RAT (P51871) Cytochrome P450 4F6 (EC 1.14.14.1) (CYPIVF6)| Length = 537 Score = 67.4 bits (163), Expect = 2e-11 Identities = 41/100 (41%), Positives = 54/100 (54%), Gaps = 3/100 (3%) Frame = -3 Query: 460 PVAAIQRKAGSDLEV-GGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRF--ENGVT 290 PV I R D+ + G +PKG + I I +H + VW D + P RF EN Sbjct: 394 PVLLISRCCSQDIVLPDGRVIPKGNICVISIFGVHHNPSVW-PDPEVYNPFRFDPENPQK 452 Query: 289 RAGKHPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRF 170 R+ P A + FS+GPR+CIGQ FAM E K +A+ L RF Sbjct: 453 RS---PLAFIPFSAGPRNCIGQTFAMSEIKVALALTLLRF 489
>CP52C_CANMA (P16496) Cytochrome P450 52A3 (EC 1.14.14.-) (CYPLIIA3)| (Alkane-inducible P450-ALK1-A) (P450-CM1) (CYP52A3-A) (Cytochrome P-450ALK) Length = 522 Score = 67.0 bits (162), Expect = 2e-11 Identities = 41/98 (41%), Positives = 53/98 (54%) Frame = -3 Query: 409 IKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGKHPNALLSFSSGPRSCI 230 I VPKG+ + + HR K+ +GEDA EF+P R+ TR K A L F+ GPR C+ Sbjct: 414 IFVPKGSSVVYSVYKTHRLKQFYGEDAYEFRPERWFEPSTR--KLGWAYLPFNGGPRICL 471 Query: 229 GQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITL 116 GQ FA+ EA VIA + Q F S + P I L Sbjct: 472 GQQFALTEASYVIARLAQMFEHLESKDETYPPNKCIHL 509
>THAS_PIG (P47787) Thromboxane-A synthase (EC 5.3.99.5) (TXA synthase) (TXS)| Length = 534 Score = 67.0 bits (162), Expect = 2e-11 Identities = 40/124 (32%), Positives = 60/124 (48%), Gaps = 3/124 (2%) Frame = -3 Query: 460 PVAAIQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAG 281 P R+A D EV G ++P GTV+ + + +H D + W F P RF R Sbjct: 407 PAFRFTREAARDCEVLGQRIPAGTVLEVAVGALHHDPKHWPHPET-FDPERFTAEAQRL- 464 Query: 280 KHPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDV---ITLRP 110 + P L F +GPRSC+G ++E K + IL++F F P+ P+ + L P Sbjct: 465 QQPFTYLPFGAGPRSCLGVQLGLLEIKLTLLHILRKFRFEACPE-TQVPLQLESKSALSP 523 Query: 109 KFGL 98 K G+ Sbjct: 524 KNGV 527
>CP53_ASPNG (P17549) Benzoate 4-monooxygenase (EC 1.14.13.12)| (Benzoate-para-hydroxylase) (Cytochrome P450 53) (BpH) Length = 517 Score = 67.0 bits (162), Expect = 2e-11 Identities = 36/106 (33%), Positives = 58/106 (54%), Gaps = 2/106 (1%) Frame = -3 Query: 394 GTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGKHPNALLSFSSGPRSCIGQNFA 215 G V+++P TIHR KE+WG DA +F P R++ + A + FS+GPR+C+G+N A Sbjct: 409 GDVVSVPSYTIHRSKEIWGPDAEQFVPERWD-PARLTPRQKAAFIPFSTGPRACVGRNVA 467 Query: 214 MIEAKAVIAMILQRFSFSLSPKYVHAPMDVIT--LRPKFGLPMILK 83 +E + + + F F + + PM+ LR GL + +K Sbjct: 468 EMELLVICGTVFRLFEFEMQQE---GPMETREGFLRKPLGLQVGMK 510
>C6A14_DROME (Q9V4U7) Probable cytochrome P450 6a14 (EC 1.14.-.-) (CYPVIA14)| Length = 509 Score = 66.6 bits (161), Expect = 3e-11 Identities = 35/85 (41%), Positives = 50/85 (58%) Frame = -3 Query: 409 IKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGKHPNALLSFSSGPRSCI 230 I + KG + IP+ IH D E++ E +F P RF+ + +HP A L F GPR+CI Sbjct: 398 IVLDKGILALIPVHNIHHDPEIYPEP-EKFDPSRFDPEEVK-NRHPMAYLPFGDGPRNCI 455 Query: 229 GQNFAMIEAKAVIAMILQRFSFSLS 155 G F I+AK + +L+RF FS+S Sbjct: 456 GLRFGKIQAKIGLVSLLRRFKFSVS 480
>CP52B_CANTR (P30607) Cytochrome P450 52A2 (EC 1.14.14.-) (CYPLIIA2)| (Alkane-inducible P450-ALK2) Length = 522 Score = 66.6 bits (161), Expect = 3e-11 Identities = 39/106 (36%), Positives = 59/106 (55%), Gaps = 1/106 (0%) Frame = -3 Query: 448 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGKHPN 269 + R G D + + V KG + + HR+K+++GEDA EF+P R+ T+ K Sbjct: 401 LPRGGGKD-GLSPVLVRKGQTVMYSVYAAHRNKQIYGEDALEFRPERWFEPETK--KLGW 457 Query: 268 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFS-FSLSPKYVHAP 134 A L F+ GPR C+GQ FA+ EA V +LQ FS ++ P ++P Sbjct: 458 AFLPFNGGPRICLGQQFALTEASYVTVRLLQEFSHLTMDPNTEYSP 503
>CP52A_CANTR (P10615) Cytochrome P450 52A1 (EC 1.14.14.-) (CYPLIIA1)| (Alkane-inducible P450-ALK1) Length = 543 Score = 66.6 bits (161), Expect = 3e-11 Identities = 36/90 (40%), Positives = 51/90 (56%) Frame = -3 Query: 439 KAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGKHPNALL 260 + G + + I + KG V+ I HRDK+++GEDA F+P R+ TR K A + Sbjct: 421 RGGGEGGLSPIAIKKGQVVMYTILATHRDKDIYGEDAYVFRPERWFEPETR--KLGWAYV 478 Query: 259 SFSSGPRSCIGQNFAMIEAKAVIAMILQRF 170 F+ GPR C+GQ FA+ EA V +LQ F Sbjct: 479 PFNGGPRICLGQQFALTEASYVTVRLLQEF 508
>CYPD_BACSU (O08394) Probable bifunctional P-450:NADPH-P450 reductase 1| [Includes: Cytochrome P450 102 (EC 1.14.14.1); NADPH--cytochrome P450 reductase (EC 1.6.2.4)] Length = 1061 Score = 66.2 bits (160), Expect = 4e-11 Identities = 38/107 (35%), Positives = 58/107 (54%), Gaps = 1/107 (0%) Frame = -3 Query: 427 DLEVGG-IKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGKHPNALLSFS 251 D +GG + I++ I +HRD++ WG+DA EF+P RFE+ + +A F Sbjct: 341 DTVIGGKFPITTNDRISVLIPQLHRDRDAWGKDAEEFRPERFEH---QDQVPHHAYKPFG 397 Query: 250 SGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITLRP 110 +G R+CIG FA+ EA V+ MIL+ F+ Y +TL+P Sbjct: 398 NGQRACIGMQFALHEATLVLGMILKYFTLIDHENYELDIKQTLTLKP 444
>THAS_HUMAN (P24557) Thromboxane-A synthase (EC 5.3.99.5) (TXA synthase) (TXS)| Length = 533 Score = 66.2 bits (160), Expect = 4e-11 Identities = 34/104 (32%), Positives = 49/104 (47%) Frame = -3 Query: 460 PVAAIQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAG 281 P R+A D EV G ++P G V+ + + +H D E W F P RF R Sbjct: 406 PAFRFTREAAQDCEVLGQRIPAGAVLEMAVGALHHDPEHW-PSPETFNPERF-TAEARQQ 463 Query: 280 KHPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPK 149 P L F +GPRSC+G ++E K + +L +F F P+ Sbjct: 464 HRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQACPE 507
>CP4F4_RAT (P51869) Cytochrome P450 4F4 (EC 1.14.14.1) (CYPIVF4)| Length = 522 Score = 66.2 bits (160), Expect = 4e-11 Identities = 38/98 (38%), Positives = 53/98 (54%), Gaps = 1/98 (1%) Frame = -3 Query: 460 PVAAIQRKAGSDLEV-GGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRA 284 PV I R+ D+ + G +PKG + I I H + VW D + P RF+ + Sbjct: 394 PVTVISRRCTQDIVLPDGRVIPKGVICIINIFATHHNPTVW-PDPEVYDPFRFDPENIK- 451 Query: 283 GKHPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRF 170 + P A + FS+GPR+CIGQ FAM E K +A+ L RF Sbjct: 452 DRSPLAFIPFSAGPRNCIGQTFAMNEMKVALALTLLRF 489
>CP4F1_RAT (P33274) Cytochrome P450 4F1 (EC 1.14.14.1) (CYPIVF1) (P450-A3)| Length = 524 Score = 66.2 bits (160), Expect = 4e-11 Identities = 45/122 (36%), Positives = 61/122 (50%), Gaps = 1/122 (0%) Frame = -3 Query: 460 PVAAIQRKAGSDLEV-GGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRA 284 PV I R D+ + G +PKG + I I IH + VW D + P RF+ + Sbjct: 394 PVTVISRCCTQDILLPDGRTIPKGIICLISIFGIHHNPSVW-PDPEVYNPFRFDPENIKD 452 Query: 283 GKHPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITLRPKF 104 P A + FS+GPR+CIGQ FAM E K +A+ L RF K ++I LR + Sbjct: 453 SS-PLAFIPFSAGPRNCIGQTFAMSEMKVALALTLLRFRLLPDDKEPRRQPELI-LRAEG 510 Query: 103 GL 98 GL Sbjct: 511 GL 512
>CP52K_CANMA (Q12589) Cytochrome P450 52A11 (EC 1.14.14.-) (CYPLIIA11)| (Alkane-inducible P450-ALK8) Length = 519 Score = 66.2 bits (160), Expect = 4e-11 Identities = 38/94 (40%), Positives = 55/94 (58%), Gaps = 2/94 (2%) Frame = -3 Query: 409 IKVPKGTVITIPIATIHRDKEVWGEDANEFKPLR-FENGVTRAGKHPNALLSFSSGPRSC 233 I V KG + + + RD++ +G+DANEF+P R FE V + G A L F+ GPR C Sbjct: 410 ILVRKGQTVMYSVYALQRDEKYYGKDANEFRPERWFEPEVRKLGW---AFLPFNGGPRIC 466 Query: 232 IGQNFAMIEAKAVIAMILQRF-SFSLSPKYVHAP 134 +GQ FA+ EA V+ ++Q F + LSP + P Sbjct: 467 LGQQFALTEASYVLVRLIQSFETLELSPDAPYPP 500
>CP343_HUMAN (Q9HB55) Cytochrome P450 3A43 (EC 1.14.14.1)| Length = 503 Score = 65.9 bits (159), Expect = 5e-11 Identities = 34/103 (33%), Positives = 54/103 (52%), Gaps = 5/103 (4%) Frame = -3 Query: 457 VAAIQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGK 278 V+ + R D+E+ G+ +PKG + +PI +H D + W E +F P RF K Sbjct: 370 VSRVTRVCKKDIEINGVFIPKGLAVMVPIYALHHDPKYWTE-PEKFCPERFSK------K 422 Query: 277 HPNAL-----LSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSF 164 + +++ + F +GPR+CIG FA+ K + LQ FSF Sbjct: 423 NKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQNFSF 465
>CP4F2_HUMAN (P78329) Cytochrome P450 4F2 (EC 1.14.13.30) (CYPIVF2)| (Leukotriene-B(4) omega-hydroxylase) (Leukotriene-B(4) 20-monooxygenase) (Cytochrome P450-LTB-omega) Length = 520 Score = 65.9 bits (159), Expect = 5e-11 Identities = 38/98 (38%), Positives = 53/98 (54%), Gaps = 1/98 (1%) Frame = -3 Query: 460 PVAAIQRKAGSDLEV-GGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRA 284 PV I R D+ + G +PKG + I + H + VW D + P RF+ + Sbjct: 394 PVPVISRHVTQDIVLPDGRVIPKGIICLISVFGTHHNPAVW-PDPEVYDPFRFDPENIKE 452 Query: 283 GKHPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRF 170 + P A + FS+GPR+CIGQ FAM E K V+A+ L RF Sbjct: 453 -RSPLAFIPFSAGPRNCIGQTFAMAEMKVVLALTLLRF 489
>CP4FE_MOUSE (Q9EP75) Cytochrome P450 4F14 (EC 1.14.13.30) (Leukotriene-B4| omega-hydroxylase) (Leukotriene-B4 20-monooxygenase) (Cytochrome P450-LTB-omega) (Cyp4f-14) Length = 524 Score = 65.9 bits (159), Expect = 5e-11 Identities = 45/122 (36%), Positives = 61/122 (50%), Gaps = 1/122 (0%) Frame = -3 Query: 460 PVAAIQRKAGSDLEV-GGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRA 284 PV I R D+ + G +PKG + I I IH + VW D + P RF+ + Sbjct: 394 PVTVISRCCTQDILLPDGRTIPKGIICLISIFGIHHNPSVW-PDPEVYDPFRFDPENIKD 452 Query: 283 GKHPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITLRPKF 104 P A + FS+GPR+CIGQ FAM E K +A+ L RF K ++I LR + Sbjct: 453 SS-PLAFIPFSAGPRNCIGQTFAMSEMKVALALTLLRFRLLPDDKEPRRQPELI-LRAEG 510 Query: 103 GL 98 GL Sbjct: 511 GL 512
>CP4P3_DROME (Q9V559) Probable cytochrome P450 4p3 (EC 1.14.-.-) (CYPIVP3)| Length = 515 Score = 65.9 bits (159), Expect = 5e-11 Identities = 41/110 (37%), Positives = 63/110 (57%), Gaps = 5/110 (4%) Frame = -3 Query: 457 VAAIQRKAGSDLEVG-GIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRF--ENGVTR 287 V A+ R+ + E+ G+ +PKG+ I + + IHR+ E W + EF+P RF EN R Sbjct: 388 VPAMGRETTRETELSNGLILPKGSQIFVHVFDIHRNPEYW-DSPEEFRPERFLPENSQNR 446 Query: 286 AGKHPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSF--SLSPKYV 143 H A + FS+G R+CIGQ FAM E K ++ +L++F + PK + Sbjct: 447 ---HTYAYIPFSAGQRNCIGQKFAMQEMKTLMVALLKQFQILPEIDPKTI 493
>CP4C1_BLADI (P29981) Cytochrome P450 4C1 (EC 1.14.14.1) (CYPIVC1)| Length = 511 Score = 65.5 bits (158), Expect = 7e-11 Identities = 42/129 (32%), Positives = 69/129 (53%), Gaps = 5/129 (3%) Frame = -3 Query: 457 VAAIQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGE----DANEFKPLRFENGVT 290 V I R D ++G VP G ++ + I +HR+++ + + + F P R Sbjct: 380 VPFIGRVLKEDTKIGDYLVPAGCMMNLQIYHVHRNQDQYPNPEAFNPDNFLPERV----- 434 Query: 289 RAGKHPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSF-SLSPKYVHAPMDVITLR 113 A +HP A + FS+GPR+CIGQ FA +E K V++ IL+ F S+ + M+ + LR Sbjct: 435 -AKRHPYAYVPFSAGPRNCIGQKFATLEEKTVLSSILRNFKVRSIEKREDLTLMNELILR 493 Query: 112 PKFGLPMIL 86 P+ G+ + L Sbjct: 494 PESGIKVEL 502
>CP4P2_DROME (Q9V557) Probable cytochrome P450 4p2 (EC 1.14.-.-) (CYPIVP2)| Length = 520 Score = 65.1 bits (157), Expect = 9e-11 Identities = 46/122 (37%), Positives = 69/122 (56%), Gaps = 4/122 (3%) Frame = -3 Query: 460 PVAAIQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRF--ENGVTR 287 P+ Q ++LE G+ +PK + I I + IHR+ + W E EF+P RF +N + R Sbjct: 392 PIMGRQTLQETELE-NGLILPKRSQINIHVFDIHRNPKYW-ESPEEFRPERFLPQNCLKR 449 Query: 286 AGKHPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSF--SLSPKYVHAPMDVITLR 113 HP A + FS+G R+CIGQ +AM E K ++ +IL+ F + PK + + ITLR Sbjct: 450 ---HPYAYIPFSAGQRNCIGQKYAMQEMKTLMVVILKHFKILPVIDPKSIVFQVG-ITLR 505 Query: 112 PK 107 K Sbjct: 506 FK 507
>C4D21_DROME (Q9VLZ7) Probable cytochrome P450 4d21 (EC 1.14.-.-) (CYPIVD21)| Length = 511 Score = 65.1 bits (157), Expect = 9e-11 Identities = 35/97 (36%), Positives = 57/97 (58%) Frame = -3 Query: 460 PVAAIQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAG 281 PV + R DL++G I +P T I + ++RD E + D FKP R+ + T + Sbjct: 382 PVPILGRYIPEDLKIGEITIPGNTSILLMPYYVYRDPEYF-PDPLVFKPERWMDMKTTSN 440 Query: 280 KHPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRF 170 P A + FSSGP++CIGQ FA ++ KA+I+ +++ + Sbjct: 441 TPPLAYIPFSSGPKNCIGQKFANLQMKALISKVIRHY 477
>THAS_RAT (P49430) Thromboxane-A synthase (EC 5.3.99.5) (TXA synthase) (TXS)| Length = 533 Score = 65.1 bits (157), Expect = 9e-11 Identities = 34/104 (32%), Positives = 50/104 (48%) Frame = -3 Query: 460 PVAAIQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAG 281 P R+A D EV G +P G+V+ I + +H D E W + F P RF R Sbjct: 406 PAFRFTREAAQDCEVLGQHIPAGSVLEIAVGALHHDPEHW-PNPETFDPERF-TAEARLQ 463 Query: 280 KHPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPK 149 + P L F +GPRSC+G ++ K + +L +F F P+ Sbjct: 464 QKPFTYLPFGAGPRSCLGVRLGLLVVKLTLLQVLHKFRFEACPE 507
>C6A13_DROME (Q9V4U9) Probable cytochrome P450 6a13 (EC 1.14.-.-) (CYPVIA13)| Length = 493 Score = 65.1 bits (157), Expect = 9e-11 Identities = 34/82 (41%), Positives = 49/82 (59%) Frame = -3 Query: 394 GTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGKHPNALLSFSSGPRSCIGQNFA 215 G+ I IP+ +IH D E++ D +F P RFE +A +HP A L F GPR+CIG+ F Sbjct: 384 GSKIIIPVHSIHHDPELY-PDPEKFDPSRFEPEEIKA-RHPFAYLPFGEGPRNCIGERFG 441 Query: 214 MIEAKAVIAMILQRFSFSLSPK 149 ++ K + +L+ F FS S K Sbjct: 442 KLQVKVGLVYLLRDFKFSRSEK 463
>CP52F_CANTR (P30608) Cytochrome P450 52A6 (EC 1.14.14.-) (CYPLIIA6)| (Alkane-inducible P450-ALK3) Length = 524 Score = 64.7 bits (156), Expect = 1e-10 Identities = 36/93 (38%), Positives = 53/93 (56%), Gaps = 1/93 (1%) Frame = -3 Query: 409 IKVPKGTVITIPIATIHRDKEVWGEDANEFKPLR-FENGVTRAGKHPNALLSFSSGPRSC 233 I +PKG+ + + HR +E +G+DA++F+P R FE + G A + F+ GPR C Sbjct: 416 IFIPKGSTVAYIVYKTHRLEEYYGKDADDFRPERWFEPSTKKLGW---AYVPFNGGPRIC 472 Query: 232 IGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAP 134 +GQ FA+ EA VI ++Q F SP V P Sbjct: 473 LGQQFALTEASYVITRLVQMFETVSSPPDVEYP 505
>CP2DI_RAT (Q64680) Cytochrome P450 2D18 (EC 1.14.14.1) (CYPIID18) (P450| 2D-29/2D-35) Length = 500 Score = 64.7 bits (156), Expect = 1e-10 Identities = 35/97 (36%), Positives = 54/97 (55%) Frame = -3 Query: 448 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGKHPN 269 + K D+EV G +PKGT + I ++++ +D+ VW E F P F + KH Sbjct: 377 VPHKTSRDIEVQGFLIPKGTTLIINLSSVLKDETVW-EKPLRFHPEHFLDAQGNFVKH-E 434 Query: 268 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSL 158 A + FS+G R+C+G+ A +E +LQRFSFS+ Sbjct: 435 AFMPFSAGRRACLGEPLARMELFLFFTCLLQRFSFSV 471
>CP4F3_HUMAN (Q08477) Cytochrome P450 4F3 (EC 1.14.13.30) (CYPIVF3)| (Leukotriene-B(4) omega-hydroxylase) (Leukotriene-B(4) 20-monooxygenase) (Cytochrome P450-LTB-omega) Length = 520 Score = 63.9 bits (154), Expect = 2e-10 Identities = 37/98 (37%), Positives = 53/98 (54%), Gaps = 1/98 (1%) Frame = -3 Query: 460 PVAAIQRKAGSDLEV-GGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRA 284 PV A+ R D+ + G +PKG + I + H + VW D + P RF+ + Sbjct: 394 PVPAVSRCCTQDIVLPDGRVIPKGIICLISVFGTHHNPAVW-PDPEVYDPFRFDPKNIKE 452 Query: 283 GKHPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRF 170 + P A + FS+GPR+CIGQ FAM E K V+ + L RF Sbjct: 453 -RSPLAFIPFSAGPRNCIGQAFAMAEMKVVLGLTLLRF 489
>CP4FB_HUMAN (Q9HBI6) Cytochrome P450 4F11 (EC 1.14.14.1) (CYPIVF11)| Length = 524 Score = 63.9 bits (154), Expect = 2e-10 Identities = 41/98 (41%), Positives = 51/98 (52%), Gaps = 1/98 (1%) Frame = -3 Query: 460 PVAAIQRKAGSDLEV-GGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRA 284 PV I R D + G +PKG V I I IH + VW D + P RF N Sbjct: 394 PVPVISRCCTQDFVLPDGRVIPKGIVCLINIIGIHYNPTVW-PDPEVYDPFRF-NQENIK 451 Query: 283 GKHPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRF 170 + P A + FS+GPR+CIGQ FAM E K V+A+ L F Sbjct: 452 ERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALTLLHF 489
>CP52D_CANMA (P16141) Cytochrome P450 52A4 (EC 1.14.14.-) (CYPLIIA4)| (Alkane-inducible P450-ALK3-A) (P450-CM2) Length = 537 Score = 63.9 bits (154), Expect = 2e-10 Identities = 37/93 (39%), Positives = 51/93 (54%) Frame = -3 Query: 448 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGKHPN 269 + R G D + I + KG + I+ HRD ++GEDAN F+P R+ TR K Sbjct: 416 LPRGGGKD-GMSPIAIKKGQNVMYTISATHRDPSIYGEDANVFRPERWFEPETR--KLGW 472 Query: 268 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRF 170 A + F+ GPR C+GQ FA+ EA V +LQ F Sbjct: 473 AYVPFNGGPRICLGQQFALTEASYVTVRLLQEF 505
>C71AI_ARATH (Q9SAB6) Cytochrome P450 71A18 (EC 1.14.-.-)| Length = 497 Score = 63.5 bits (153), Expect = 3e-10 Identities = 41/124 (33%), Positives = 58/124 (46%) Frame = -3 Query: 448 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGKHPN 269 + R D++V G + GT + I +IHRD +WG DA EFKP R + Sbjct: 368 LPRLLTEDVKVKGYDIAAGTEVLINAWSIHRDPAIWGPDAEEFKPERHLDSTLDYHGQDL 427 Query: 268 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITLRPKFGLPMI 89 + F SG R C G N AM + +A ++ RF +S+ P D L FGL + Sbjct: 428 KYIPFGSGRRICPGINLAMGLVEVTLANLVGRFDWSVDP---GPNGDQPDLAEDFGLDVC 484 Query: 88 LKSP 77 K+P Sbjct: 485 RKNP 488
>CP133_DROME (Q9VGB3) Probable cytochrome P450 313a3 (EC 1.14.-.-)| (CYPCCCXIIIA3) Length = 492 Score = 63.5 bits (153), Expect = 3e-10 Identities = 32/89 (35%), Positives = 49/89 (55%) Frame = -3 Query: 412 GIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGKHPNALLSFSSGPRSC 233 G+ +PKG I I I HR+++ WG D + F P F R +HP A + FS G R+C Sbjct: 380 GVVIPKGVGIGIDIFATHRNRDHWGTDPSSFNPDHFLPDNVR-DRHPYAYIPFSKGRRNC 438 Query: 232 IGQNFAMIEAKAVIAMILQRFSFSLSPKY 146 IG + ++ +K ++ IL+ S S +Y Sbjct: 439 IGWKYGLMSSKLALSKILRNCKVSTSFRY 467
>CP1A1_RAT (P00185) Cytochrome P450 1A1 (EC 1.14.14.1) (CYP1A1) (CYPIA1)| (P450-C) (P450MT2) [Contains: Cytochrome P450MT2A; Cytochrome P450MT2B] Length = 524 Score = 63.2 bits (152), Expect = 3e-10 Identities = 34/113 (30%), Positives = 58/113 (51%), Gaps = 1/113 (0%) Frame = -3 Query: 427 DLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGKH-PNALLSFS 251 D + G +PKG + + ++ D+E+WG D NEF+P RF KH ++ F Sbjct: 397 DTSLNGFYIPKGHCVFVNQWQVNHDQELWG-DPNEFRPERFLTSSGTLDKHLSEKVILFG 455 Query: 250 SGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITLRPKFGLPM 92 G R CIG+ +E +A++LQ+ F++SP + + + P +GL + Sbjct: 456 LGKRKCIGETIGRLEVFLFLAILLQQMEFNVSPG------EKVDMTPAYGLTL 502
>C4AA1_DROME (Q9V7G5) Probable cytochrome P450 4aa1 (EC 1.14.-.-) (CYPIVAA1)| Length = 514 Score = 63.2 bits (152), Expect = 3e-10 Identities = 45/128 (35%), Positives = 67/128 (52%), Gaps = 3/128 (2%) Frame = -3 Query: 457 VAAIQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRF--ENGVTRA 284 V I RK G ++ + +P G+ + I HR ++ D +F+P RF EN R Sbjct: 382 VPLIARKLGEEVRLAKHTLPAGSNVFICPYATHRLAHIY-PDPEKFQPERFSPENSENR- 439 Query: 283 GKHPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFS-FSLSPKYVHAPMDVITLRPK 107 HP A L FS+GPR CIG FA++E K +++ +L+ + ++ K A ITLR Sbjct: 440 --HPYAFLPFSAGPRYCIGNRFAIMEIKTIVSRLLRSYQLLPVTGKTTIAATFRITLRAS 497 Query: 106 FGLPMILK 83 GL + LK Sbjct: 498 GGLWVRLK 505
>CP2D4_RAT (P13108) Cytochrome P450 2D4 (EC 1.14.14.1) (CYPIID4) (P450-DB4)| (P450-CMF3) (Debrisoquine 4-hydroxylase) Length = 500 Score = 62.8 bits (151), Expect = 4e-10 Identities = 34/97 (35%), Positives = 53/97 (54%) Frame = -3 Query: 448 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGKHPN 269 + K D+EV G +PKGT + ++++ +D+ VW E F P F + KH Sbjct: 377 VPHKTSRDIEVQGFLIPKGTTLITNLSSVLKDETVW-EKPLRFHPEHFLDAQGNFVKH-E 434 Query: 268 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSL 158 A + FS+G R+C+G+ A +E +LQRFSFS+ Sbjct: 435 AFMPFSAGRRACLGEPLARMELFLFFTCLLQRFSFSV 471
>C505_FUSOX (Q9Y8G7) Bifunctional P-450:NADPH-P450 reductase (Fatty acid| omega-hydroxylase) (P450foxy) [Includes: Cytochrome P450 505 (EC 1.14.14.1); NADPH--cytochrome P450 reductase (EC 1.6.2.4)] Length = 1066 Score = 62.8 bits (151), Expect = 4e-10 Identities = 39/121 (32%), Positives = 66/121 (54%), Gaps = 4/121 (3%) Frame = -3 Query: 460 PVAAIQRKAGSDLEVGG-IKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRF-ENGVTR 287 P+ A +A D +GG V KG ++T ++ H D V+G DA++F P R ++ R Sbjct: 329 PITAFGLEAIDDTFLGGKYLVKKGEIVTALLSRGHVDPVVYGNDADKFIPERMLDDEFAR 388 Query: 286 AGK-HPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLS-PKYVHAPMDVITLR 113 K +PN F +G R+CIG+ FA E+ + ++ Q F+F+++ P Y +T++ Sbjct: 389 LNKEYPNCWKPFGNGKRACIGRPFAWQESLLAMVVLFQNFNFTMTDPNYALEIKQTLTIK 448 Query: 112 P 110 P Sbjct: 449 P 449
>C4G15_DROME (Q9VYY4) Cytochrome P450 4g15 (EC 1.14.-.-) (CYPIVG15)| Length = 574 Score = 62.8 bits (151), Expect = 4e-10 Identities = 33/103 (32%), Positives = 59/103 (57%), Gaps = 6/103 (5%) Frame = -3 Query: 460 PVAAIQRKAGSDLEV--GGIKVPKGTVITIPIATIHRDKEVWGE----DANEFKPLRFEN 299 PV I R+ DL++ G +P+G +T+ +HR+ +V+ D + F P R Sbjct: 444 PVPLIARELQEDLKLNSGNYVIPRGATVTVATVLLHRNPKVYANPNVFDPDNFLPER--- 500 Query: 298 GVTRAGKHPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRF 170 +A +H A + FS+GPRSC+G+ +AM++ K +++ IL+ + Sbjct: 501 ---QANRHYYAFVPFSAGPRSCVGRKYAMLKLKILLSTILRNY 540
>C4D20_DROME (Q9W011) Probable cytochrome P450 4d20 (EC 1.14.-.-) (CYPIVD20)| Length = 510 Score = 62.8 bits (151), Expect = 4e-10 Identities = 36/95 (37%), Positives = 55/95 (57%) Frame = -3 Query: 460 PVAAIQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAG 281 PV AI R A +LE+G +P T I + + HRD + D F+P RF + G Sbjct: 382 PVPAIGRHAQKELEIGDKTIPANTSIYLVLYYAHRDANYF-PDPLSFRPERFLEDQEQ-G 439 Query: 280 KHPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQ 176 + A + FS+GP++CIGQ FA++E K +I+ +L+ Sbjct: 440 HNTFAYVPFSAGPKNCIGQKFAVLEMKVLISKVLR 474
>CP135_DROME (Q9VGB5) Probable cytochrome P450 313a5 (EC 1.14.-.-)| (CYPCCCXIIIA5) Length = 487 Score = 62.8 bits (151), Expect = 4e-10 Identities = 32/89 (35%), Positives = 49/89 (55%) Frame = -3 Query: 412 GIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGKHPNALLSFSSGPRSC 233 G +P+G + I I HR+K++WG AN F P F RA + P + L FS G ++C Sbjct: 375 GFYIPEGVTLMIDIFHTHRNKDIWGPQANAFNPDNFLPENKRA-RPPYSYLPFSKGKKTC 433 Query: 232 IGQNFAMIEAKAVIAMILQRFSFSLSPKY 146 +G ++I AK +A IL+ + S + Y Sbjct: 434 LGWKLSLISAKLALAKILRNYMLSTTFLY 462
>CP52H_CANTR (P30610) Cytochrome P450 52A8 (EC 1.14.14.-) (CYPLIIA8)| (Alkane-inducible P450-ALK5) Length = 517 Score = 62.8 bits (151), Expect = 4e-10 Identities = 41/112 (36%), Positives = 58/112 (51%), Gaps = 1/112 (0%) Frame = -3 Query: 448 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGKHPN 269 + R GSD + V KG ++ I + H D +G+DA EF+P R+ TR K Sbjct: 396 LPRGGGSDGN-SPVLVKKGEAVSYGINSTHLDPVYYGDDAAEFRPERWNEPSTR--KLGW 452 Query: 268 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRF-SFSLSPKYVHAPMDVITL 116 A L F+ GPR C+GQ FA+ EA V+ + Q F + L P V+ P + L Sbjct: 453 AYLPFNGGPRICLGQQFALTEAGYVLVRLAQSFDTLELKPPVVYPPKRLTNL 504
>CP52L_DEBHA (Q9Y757) Cytochrome P450 52A12 (EC 1.14.14.-) (Alkane hydroxylase| 1) (Alkane-inducible p450alk 1) (DH-ALK2) Length = 519 Score = 62.8 bits (151), Expect = 4e-10 Identities = 33/80 (41%), Positives = 48/80 (60%) Frame = -3 Query: 409 IKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGKHPNALLSFSSGPRSCI 230 I + KG +T + +HRD++ +G+D+ F+P R+ TR K A L F+ GPR C+ Sbjct: 411 IFIAKGQTVTYTVYAMHRDEQFYGKDSEVFRPERWFEPETR--KLGWAFLPFNGGPRICL 468 Query: 229 GQNFAMIEAKAVIAMILQRF 170 GQ FA+ EA VIA + Q F Sbjct: 469 GQQFALTEASYVIARLAQLF 488
>CP17A_MOUSE (P27786) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 507 Score = 62.4 bits (150), Expect = 6e-10 Identities = 40/108 (37%), Positives = 55/108 (50%), Gaps = 6/108 (5%) Frame = -3 Query: 460 PVAA--IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTR 287 PVA I KA D +G +PK T + I + +H DK W + + F P RF + Sbjct: 364 PVAPLLIPHKANIDSSIGEFAIPKDTHVIINLWALHHDKNEW-DQPDRFMPERF---LDP 419 Query: 286 AGKH----PNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLS 155 G H + L F +GPRSCIG+ A E +A++LQRF F +S Sbjct: 420 TGSHLITPTPSYLPFGAGPRSCIGEALARQELFIFMALLLQRFDFDVS 467
>CP4E3_DROME (Q9VL92) Cytochrome P450 4e3 (EC 1.14.-.-) (CYPIVE3)| Length = 526 Score = 62.4 bits (150), Expect = 6e-10 Identities = 34/96 (35%), Positives = 54/96 (56%) Frame = -3 Query: 457 VAAIQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGK 278 V I R D ++ G VPKGT + + + + + ++ +D + F+P RFE Sbjct: 374 VPFIGRYCDKDYDINGSIVPKGTTLNLALILLGYNDRIF-KDPHHFRPERFEEEKPA--- 429 Query: 277 HPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRF 170 P L FS+GPR+CIGQ FA++E K VI+ +++ F Sbjct: 430 -PFEYLPFSAGPRNCIGQKFALLELKTVISKVVRSF 464
>CP52E_CANMA (P24458) Cytochrome P450 52A5 (EC 1.14.14.-) (CYPLIIA5)| (Alkane-inducible P450-ALK2-A) (CYP52A3-B) Length = 523 Score = 62.4 bits (150), Expect = 6e-10 Identities = 38/98 (38%), Positives = 52/98 (53%) Frame = -3 Query: 409 IKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGKHPNALLSFSSGPRSCI 230 I VPKG+ + + HR +E +G+DA EF+P R+ TR K A + F+ GPR C+ Sbjct: 415 IFVPKGSSVVYTVYKTHRLEEYYGKDAYEFRPERWFEPSTR--KLGWAYVPFNGGPRICL 472 Query: 229 GQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITL 116 GQ FA+ EA VI + Q F S + P I L Sbjct: 473 GQQFALTEASYVITRLAQMFEHLESKDETYPPNKCIHL 510
>CP2L1_PANAR (Q27712) Cytochrome P450 2L1 (EC 1.14.14.1) (CYPIIL1)| Length = 492 Score = 62.4 bits (150), Expect = 6e-10 Identities = 36/100 (36%), Positives = 55/100 (55%) Frame = -3 Query: 448 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGKHPN 269 + D E+ G ++PKGTV+ + HRD W E NEF P F + + K + Sbjct: 367 VSHYTNQDTELAGYRLPKGTVVMSHLECCHRDPSYW-EKPNEFYPEHFLDDQGKFVKREH 425 Query: 268 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPK 149 L++FS G R C+G++ A +E ++ ILQ F+FS +PK Sbjct: 426 -LVNFSVGRRVCVGESLARMELFVFLSAILQNFTFS-APK 463
>CP52M_DEBHA (Q9Y758) Cytochrome P450 52A13 (EC 1.14.14.-) (Alkane hydroxylase| 2) (Alkane-inducible p450alk 2) (DH-ALK2) Length = 519 Score = 62.4 bits (150), Expect = 6e-10 Identities = 32/80 (40%), Positives = 48/80 (60%) Frame = -3 Query: 409 IKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGKHPNALLSFSSGPRSCI 230 I V KGT + + + HR +E +G+DA+EFKP R+ + K A + F+ GPR C+ Sbjct: 412 IYVGKGTTVAYSVYSTHRMEEYYGKDADEFKPERW----AESRKLGWAYVPFNGGPRICL 467 Query: 229 GQNFAMIEAKAVIAMILQRF 170 GQ FA+ EA ++ +LQ F Sbjct: 468 GQQFALTEASYIVTRLLQMF 487
>CP4D8_DROME (Q9VS79) Cytochrome P450 4d8 (EC 1.14.-.-) (CYPIVD8)| Length = 463 Score = 62.0 bits (149), Expect = 7e-10 Identities = 42/128 (32%), Positives = 68/128 (53%), Gaps = 5/128 (3%) Frame = -3 Query: 460 PVAAIQRKAGSDLEV-----GGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENG 296 PV + RK +D + G +P G+ I I I +HR E + + +EF P R ENG Sbjct: 333 PVPIVGRKLQTDFKYTHSVHGDGVIPAGSEIIIGIFGVHRQPETF-PNPDEFIPERHENG 391 Query: 295 VTRAGKHPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITL 116 A P ++ FS+GPR+CIGQ FA +E K ++A I++ + + V ++++ L Sbjct: 392 SRVA---PFKMIPFSAGPRNCIGQKFAQLEMKMMLAKIVREYELLPMGQRVECIVNIV-L 447 Query: 115 RPKFGLPM 92 R + G + Sbjct: 448 RSETGFQL 455
>CP4P1_DROME (Q9V558) Cytochrome P450 4p1 (EC 1.14.-.-) (CYPIVP1)| Length = 513 Score = 62.0 bits (149), Expect = 7e-10 Identities = 38/99 (38%), Positives = 60/99 (60%), Gaps = 3/99 (3%) Frame = -3 Query: 457 VAAIQRKAGSDLEVG-GIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRF--ENGVTR 287 V + R+A + E+ G+ +PKG ITI + IHR+ + W + EF+P RF EN R Sbjct: 386 VPIMGREAVQETELANGLILPKGAQITIHVFDIHRNAKYW-DSPEEFRPERFLPENVQDR 444 Query: 286 AGKHPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRF 170 H A + FS+G R+CIG+ +AM E K ++ ++L++F Sbjct: 445 ---HTYAYVPFSAGQRNCIGKKYAMQEMKTLMVVLLKQF 480
>CP4E2_DROME (Q27606) Cytochrome P450 4e2 (EC 1.14.-.-) (CYPIVE2)| Length = 526 Score = 62.0 bits (149), Expect = 7e-10 Identities = 35/96 (36%), Positives = 59/96 (61%) Frame = -3 Query: 457 VAAIQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGK 278 V I R D + G VPKGT + + + + +++V+ +D ++F+P RFE + + G Sbjct: 375 VPFIGRFTEKDYVIDGDLVPKGTTLNLGLVMLGYNEKVF-KDPHKFRPERFE--LEKPG- 430 Query: 277 HPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRF 170 P + FS+GPR+CIGQ FA++E K V++ I++ F Sbjct: 431 -PFEYVPFSAGPRNCIGQKFALLEIKTVVSKIIRNF 465
>CP2D1_RAT (P10633) Cytochrome P450 2D1 (EC 1.14.14.1) (CYPIID1) (P450-DB1)| (P450-CMF1A) (P450-UT-7) (Debrisoquine 4-hydroxylase) Length = 504 Score = 62.0 bits (149), Expect = 7e-10 Identities = 34/97 (35%), Positives = 54/97 (55%) Frame = -3 Query: 448 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGKHPN 269 + R D+EV +PKGT + I ++++ +D+ VW E + F P F + KH Sbjct: 377 LPRFTSCDIEVQDFVIPKGTTLIINLSSVLKDETVW-EKPHRFHPEHFLDAQGNFVKH-E 434 Query: 268 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSL 158 A + FS+G R+C+G+ A +E +LQRFSFS+ Sbjct: 435 AFMPFSAGRRACLGEPLARMELFLFFTCLLQRFSFSV 471
>C28C1_DROME (Q9VYT8) Probable cytochrome P450 28c1 (EC 1.14.-.-) (CYPXXVIIIC1)| Length = 505 Score = 62.0 bits (149), Expect = 7e-10 Identities = 30/87 (34%), Positives = 49/87 (56%) Frame = -3 Query: 409 IKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGKHPNALLSFSSGPRSCI 230 +K+ G + +PI +H D +++ E + F+P RF +G + K L F +GPR C+ Sbjct: 387 LKLRPGDHVMVPIYALHNDPDLYPEP-DVFRPERFLDGGLKNCKQQGIFLGFGNGPRQCV 445 Query: 229 GQNFAMIEAKAVIAMILQRFSFSLSPK 149 G + AKA +A I+QRF +SP+ Sbjct: 446 GMRLGLAMAKAALAAIVQRFEVVVSPR 472
>CP9F2_DROME (Q9VG82) Probable cytochrome P450 9f2 (EC 1.14.-.-) (CYPIXF2)| Length = 516 Score = 61.6 bits (148), Expect = 1e-09 Identities = 44/125 (35%), Positives = 68/125 (54%), Gaps = 8/125 (6%) Frame = -3 Query: 451 AIQRKAGSDL--EVGG--IKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRA 284 A+ R+ D+ +V G ++V KG VI +P HRD + + E+ +F P RF + + Sbjct: 386 AVDRECNKDITFDVDGQKVEVKKGDVIWLPTCGFHRDPKYF-ENPMKFDPERFSDE-NKE 443 Query: 283 GKHPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVIT----L 116 P F G R+CIG FA++EAKAVI +L+ + F+ + K P+++IT L Sbjct: 444 SIQPFTYFPFGLGQRNCIGSRFALLEAKAVIYYLLKDYRFAPAKKSC-IPLELITSGFQL 502 Query: 115 RPKFG 101 PK G Sbjct: 503 SPKGG 507
>CP2D6_PANTR (Q2XNC8) Cytochrome P450 2D6 (EC 1.14.14.1) (CYPIID6)| Length = 497 Score = 61.6 bits (148), Expect = 1e-09 Identities = 34/90 (37%), Positives = 51/90 (56%) Frame = -3 Query: 427 DLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGKHPNALLSFSS 248 D+EV G ++PKGT + ++++ +DK VW E F P F + K P A L FS+ Sbjct: 381 DIEVQGFRIPKGTTLFTNLSSVLKDKAVW-EKPFRFHPEHFLDAQGHFVK-PEAFLPFSA 438 Query: 247 GPRSCIGQNFAMIEAKAVIAMILQRFSFSL 158 G R+C+G+ A +E +LQ FSFS+ Sbjct: 439 GRRACLGEPLARMELFLFFTSLLQHFSFSV 468
>C135A_MYCTU (O08447) Putative cytochrome P450 135A1 (EC 1.14.-.-)| Length = 449 Score = 61.6 bits (148), Expect = 1e-09 Identities = 41/121 (33%), Positives = 59/121 (48%), Gaps = 2/121 (1%) Frame = -3 Query: 457 VAAIQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGK 278 +A+ RK + E+GG ++P GTV+ I H EV EF+P RF +G Sbjct: 314 IASTARKVTAPAEIGGWRLPAGTVVNTSILLAHAS-EVSHPKPTEFRPSRFLDGSVA--- 369 Query: 277 HPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLS-PKYVHAPM-DVITLRPKF 104 PN L F G R C+G FA+ E ++ I +RF+ + + P P+ IT PK Sbjct: 370 -PNTWLPFGGGVRRCLGFGFALTEGAVILQEIFRRFTITAAGPSKGETPLVRNITTVPKH 428 Query: 103 G 101 G Sbjct: 429 G 429
>C4AC3_DROME (Q9VMS7) Probable cytochrome P450 4ac3 (EC 1.14.-.-) (CYPIVAC3)| Length = 509 Score = 61.6 bits (148), Expect = 1e-09 Identities = 35/85 (41%), Positives = 52/85 (61%), Gaps = 2/85 (2%) Frame = -3 Query: 418 VGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRF--ENGVTRAGKHPNALLSFSSG 245 + G+ +PK I+I I I RD + + N+F P RF EN V R HP A + FS+G Sbjct: 395 MNGLVLPKNAQISIHIYDIMRDARHFPKP-NQFLPERFLPENSVNR---HPFAFVPFSAG 450 Query: 244 PRSCIGQNFAMIEAKAVIAMILQRF 170 PR+CIGQ F ++E K ++A +++ F Sbjct: 451 PRNCIGQKFGVLEIKVLLAAVIRNF 475
>CP2DR_MESAU (Q9QYG6) Cytochrome P450 2D27 (EC 1.14.14.-) (CYPIID27)| Length = 500 Score = 61.6 bits (148), Expect = 1e-09 Identities = 35/97 (36%), Positives = 53/97 (54%) Frame = -3 Query: 448 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGKHPN 269 I D+EV G +PKGT + ++++ +D+ VW E F P F + R KH Sbjct: 377 IPHMTSHDVEVQGFLIPKGTTLIPNLSSVLKDETVW-EKPLHFHPEHFLDAQGRFVKH-E 434 Query: 268 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSL 158 A + FS+G R+C+G+ A +E +LQRFSFS+ Sbjct: 435 AFMPFSAGRRACLGEPLARMELFLFFTCLLQRFSFSV 471
>CP2D3_RAT (P12938) Cytochrome P450 2D3 (EC 1.14.14.1) (CYPIID3) (P450-DB3)| (Debrisoquine 4-hydroxylase) Length = 500 Score = 61.6 bits (148), Expect = 1e-09 Identities = 34/97 (35%), Positives = 53/97 (54%) Frame = -3 Query: 448 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGKHPN 269 + K D+EV G +PKGT + ++++ +D+ VW E F P F + KH Sbjct: 377 LPHKTSRDIEVQGFLIPKGTTLIPNLSSVLKDETVW-EKPLRFHPEHFLDAQGNFVKH-E 434 Query: 268 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSL 158 A + FS+G R+C+G+ A +E +LQRFSFS+ Sbjct: 435 AFMPFSAGRRACLGEPLARMELFLFFTCLLQRFSFSV 471
>CP6L1_BLAGE (Q9GQM9) Cytochrome P450 6l1 (EC 1.14.-.-) (CYPVIL1)| Length = 503 Score = 60.8 bits (146), Expect = 2e-09 Identities = 34/97 (35%), Positives = 53/97 (54%), Gaps = 2/97 (2%) Frame = -3 Query: 460 PVAAIQRKAGSDLEVGG--IKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTR 287 P++ I R D + G + + KGT I + + +HRD ++ D +F P RF N + Sbjct: 363 PMSFIDRVCLHDYHIPGTDVVIEKGTPIFVSLLGLHRDS-IFYPDPEDFNPERF-NKEKK 420 Query: 286 AGKHPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQ 176 +G HP + + F GPR+CIG ++ K VI M+LQ Sbjct: 421 SGVHPFSYIPFGDGPRNCIGLRLGLMSVKLVIIMLLQ 457
>CP4E5_DROMT (O44221) Cytochrome P450 4e5, mitochondrial precursor (EC 1.14.-.-)| (CYPIVE5) Length = 522 Score = 60.8 bits (146), Expect = 2e-09 Identities = 35/96 (36%), Positives = 53/96 (55%) Frame = -3 Query: 457 VAAIQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGK 278 V I R D + G +PKGT + + I + D V+ E+ + F P RFE + Sbjct: 374 VPFIGRYTDKDYNIHGTIMPKGTTLNLGIIVLGYDDRVF-EEPHRFYPERFE----KQKP 428 Query: 277 HPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRF 170 P + FS+GPR+CIGQ FA++E K VI+ +++ F Sbjct: 429 GPFEYVPFSAGPRNCIGQKFALLELKTVISKLVRTF 464
>C97B3_ARATH (O23365) Cytochrome P450 97B3 (EC 1.14.-.-)| Length = 580 Score = 60.8 bits (146), Expect = 2e-09 Identities = 38/109 (34%), Positives = 54/109 (49%), Gaps = 21/109 (19%) Frame = -3 Query: 421 EVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRF-----ENGV----------TR 287 E G KVPKGT I I + +HR W ++ ++F+P RF NG+ + Sbjct: 443 EKEGHKVPKGTDIFISVYNLHRSPYFW-DNPHDFEPERFLRTKESNGIEGWAGFDPSRSP 501 Query: 286 AGKHPN------ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSL 158 +PN A L F GPR CIG FA++E+ +AM+ Q+F L Sbjct: 502 GALYPNEIIADFAFLPFGGGPRKCIGDQFALMESTVALAMLFQKFDVEL 550
>C86A1_ARATH (P48422) Cytochrome P450 86A1 (EC 1.14.-.-) (CYPLXXXVI)| (P450-dependent fatty acid omega-hydroxylase) Length = 513 Score = 60.8 bits (146), Expect = 2e-09 Identities = 37/118 (31%), Positives = 63/118 (53%), Gaps = 3/118 (2%) Frame = -3 Query: 427 DLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGKHPN---ALLS 257 D+ G VP+G+ +T I +I R K +WGED EF+P R+ + P ++ Sbjct: 389 DVLPDGTFVPRGSTVTYSIYSIGRMKTIWGEDCLEFRPERWLTADGERFETPKDGYKFVA 448 Query: 256 FSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITLRPKFGLPMILK 83 F++GPR+C+G++ A + K+V + +L R+ P + +TL K GL + L+ Sbjct: 449 FNAGPRTCLGKDLAYNQMKSVASAVLLRYRVFPVPGHRVEQKMSLTLFMKNGLRVYLQ 506
>CP132_DROME (Q9VGB4) Probable cytochrome P450 313a2 (EC 1.14.-.-)| (CYPCCCXIIIA2) Length = 493 Score = 60.8 bits (146), Expect = 2e-09 Identities = 32/100 (32%), Positives = 51/100 (51%), Gaps = 1/100 (1%) Frame = -3 Query: 442 RKAGSDLEVG-GIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGKHPNA 266 R+ DL + G+ +PKG I+I I R+ + WG +A +F P F +HP A Sbjct: 369 RETLEDLRLSNGVVIPKGMTISIDIFNTQRNTDYWGSEAAQFNPENFLPEKIH-DRHPYA 427 Query: 265 LLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKY 146 + FS G R+CIG + ++ +K + IL+ + S Y Sbjct: 428 FIPFSKGKRNCIGWRYGLMSSKLALVKILRNYKLKTSFPY 467
>CP2D6_HUMAN (P10635) Cytochrome P450 2D6 (EC 1.14.14.1) (CYPIID6) (P450-DB1)| (Debrisoquine 4-hydroxylase) Length = 497 Score = 60.5 bits (145), Expect = 2e-09 Identities = 33/90 (36%), Positives = 51/90 (56%) Frame = -3 Query: 427 DLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGKHPNALLSFSS 248 D+EV G ++PKGT + ++++ +D+ VW E F P F + K P A L FS+ Sbjct: 381 DIEVQGFRIPKGTTLITNLSSVLKDEAVW-EKPFRFHPEHFLDAQGHFVK-PEAFLPFSA 438 Query: 247 GPRSCIGQNFAMIEAKAVIAMILQRFSFSL 158 G R+C+G+ A +E +LQ FSFS+ Sbjct: 439 GRRACLGEPLARMELFLFFTSLLQHFSFSV 468
>C71AD_ARATH (O49342) Cytochrome P450 71A13 (EC 1.14.-.-)| Length = 497 Score = 60.5 bits (145), Expect = 2e-09 Identities = 35/96 (36%), Positives = 52/96 (54%), Gaps = 1/96 (1%) Frame = -3 Query: 448 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLR-FENGVTRAGKHP 272 + R D++V G + GT + I I RD +WG DA EFKP R ++G+ GK+ Sbjct: 368 LPRLLSEDVKVKGYNIAAGTEVIINAWAIQRDTAIWGPDAEEFKPERHLDSGLDYHGKNL 427 Query: 271 NALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSF 164 N + F SG R C G N A+ A+ +A ++ RF + Sbjct: 428 N-YIPFGSGRRICPGINLALGLAEVTVANLVGRFDW 462
>C28D2_DROME (Q9VMT6) Probable cytochrome P450 28d2 (EC 1.14.-.-) (CYPXXVIIID2)| Length = 501 Score = 60.5 bits (145), Expect = 2e-09 Identities = 31/90 (34%), Positives = 48/90 (53%), Gaps = 3/90 (3%) Frame = -3 Query: 409 IKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRF---ENGVTRAGKHPNALLSFSSGPR 239 + + G V+TIP+ +H D + + ED FKP RF G ++ + L+F GPR Sbjct: 386 VHLKPGDVVTIPVKALHHDPQYY-EDPLTFKPERFLESNGGGMKSYRDRGVYLAFGDGPR 444 Query: 238 SCIGQNFAMIEAKAVIAMILQRFSFSLSPK 149 C G FA+ + KA + IL+ F ++PK Sbjct: 445 HCPGMRFALTQLKAALVEILRNFEIKVNPK 474
>C86A2_ARATH (O23066) Cytochrome P450 86A2 (EC 1.14.-.-)| Length = 553 Score = 60.1 bits (144), Expect = 3e-09 Identities = 38/114 (33%), Positives = 59/114 (51%), Gaps = 4/114 (3%) Frame = -3 Query: 427 DLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGKHPN----ALL 260 D+ G VP G+ +T I R K WGED EFKP R+ + GK N + Sbjct: 393 DILPDGTFVPAGSSVTYSIYAAGRMKSTWGEDCLEFKPERWIS--PDDGKFVNHDQYRFV 450 Query: 259 SFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITLRPKFGL 98 +F++GPR C+G++ A ++ K + A +L R +++P + +TL K GL Sbjct: 451 AFNAGPRICLGKDLAYLQMKTIAAAVLLRHRLTVAPGHKVEQKMSLTLFMKNGL 504
>C4AC1_DROME (Q9VMS9) Probable cytochrome P450 4ac1 (EC 1.14.-.-) (CYPIVAC1)| Length = 509 Score = 60.1 bits (144), Expect = 3e-09 Identities = 39/98 (39%), Positives = 58/98 (59%), Gaps = 2/98 (2%) Frame = -3 Query: 457 VAAIQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRF--ENGVTRA 284 V I R+ + V G+ +PK T I+I I I RD + + + F+P RF EN V R Sbjct: 382 VPFIGRQCVEETVVNGMVMPKDTQISIHIYDIMRDPRHFPKP-DLFQPDRFLPENTVNR- 439 Query: 283 GKHPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRF 170 HP A + FS+G R+CIGQ FA++E K ++A +++ F Sbjct: 440 --HPFAYVPFSAGQRNCIGQKFAILEMKVLLAAVIRNF 475
>CP2DG_CAVPO (Q64403) Cytochrome P450 2D16 (EC 1.14.14.1) (CYPIID16)| Length = 500 Score = 60.1 bits (144), Expect = 3e-09 Identities = 34/90 (37%), Positives = 51/90 (56%) Frame = -3 Query: 427 DLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGKHPNALLSFSS 248 D EV G +PKGT++ ++++ +D+ VW E F P F + R K A + FS+ Sbjct: 384 DTEVQGFLIPKGTMLFTNLSSVLKDETVW-EKPLHFHPGHFLDAEGRFVKR-EAFMPFSA 441 Query: 247 GPRSCIGQNFAMIEAKAVIAMILQRFSFSL 158 GPR C+G+ A +E +LQRFSFS+ Sbjct: 442 GPRICLGEPLARMELFLFFTSLLQRFSFSV 471
>CP2D6_PANPA (Q2XNC9) Cytochrome P450 2D6 (EC 1.14.14.1) (CYPIID6)| Length = 497 Score = 60.1 bits (144), Expect = 3e-09 Identities = 33/90 (36%), Positives = 51/90 (56%) Frame = -3 Query: 427 DLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGKHPNALLSFSS 248 D+EV G ++PKGT + ++++ +D+ VW E F P F + K P A L FS+ Sbjct: 381 DIEVQGFRIPKGTTLFTNLSSVLKDEAVW-EKPFRFHPEHFLDAQGHFVK-PEAFLPFSA 438 Query: 247 GPRSCIGQNFAMIEAKAVIAMILQRFSFSL 158 G R+C+G+ A +E +LQ FSFS+ Sbjct: 439 GRRACLGEPLARMELFLFFTSLLQHFSFSV 468
>CP17A_RAT (P11715) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 507 Score = 60.1 bits (144), Expect = 3e-09 Identities = 38/108 (35%), Positives = 54/108 (50%), Gaps = 6/108 (5%) Frame = -3 Query: 460 PVAA--IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTR 287 PVA I KA D +G VPK T + + + +H D+ W + ++F P RF + Sbjct: 364 PVAPMLIPHKANVDSSIGEFTVPKDTHVVVNLWALHHDENEW-DQPDQFMPERF---LDP 419 Query: 286 AGKH----PNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLS 155 G H + L F +GPRSCIG+ A E A++LQRF +S Sbjct: 420 TGSHLITPTQSYLPFGAGPRSCIGEALARQELFVFTALLLQRFDLDVS 467
>CP52I_CANMA (Q12586) Cytochrome P450 52A9 (EC 1.14.14.-) (CYPLIIA9)| (Alkane-inducible P450-ALK5-A) Length = 521 Score = 60.1 bits (144), Expect = 3e-09 Identities = 36/99 (36%), Positives = 52/99 (52%), Gaps = 1/99 (1%) Frame = -3 Query: 409 IKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGKHPNALLSFSSGPRSCI 230 I + KG V++ I + H D +G DA F P R+ T+ K A L F+ GPR C+ Sbjct: 412 IFIKKGAVVSYGINSTHLDPMYYGPDARLFNPDRWSKPETK--KLGWAFLPFNGGPRICL 469 Query: 229 GQNFAMIEAKAVIAMILQRF-SFSLSPKYVHAPMDVITL 116 GQ FA+ EA V+ ++Q F L+P V+ P + L Sbjct: 470 GQQFALTEASYVLVRMIQNFKELELTPNTVYPPRRLTNL 508
>C81E1_GLYEC (P93147) Cytochrome P450 81E1 (EC 1.14.13.89) (Isoflavone| 2'-hydroxylase) (P450 91A4) (CYP GE-3) Length = 499 Score = 59.7 bits (143), Expect = 4e-09 Identities = 41/125 (32%), Positives = 61/125 (48%), Gaps = 2/125 (1%) Frame = -3 Query: 448 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGKHPN 269 + + +GG KVP+ T++ I IHRD E+W E A FKP RFE + G+ Sbjct: 371 LPHSTSDECNIGGYKVPQDTIVLINAWAIHRDPELWTE-ATTFKPERFE----KKGE-LE 424 Query: 268 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSL--SPKYVHAPMDVITLRPKFGLP 95 L++F G R+C G+ A+ +A+++Q F + L K A D TL L Sbjct: 425 KLIAFGMGRRACPGEGLAIRAISMTLALLIQCFDWKLINGDKIDLAERDGFTLTKLVPLK 484 Query: 94 MILKS 80 + KS Sbjct: 485 AMCKS 489
>CP4E1_DROME (Q9V4T5) Probable cytochrome P450 4e1 (EC 1.14.-.-) (CYPIVE1)| Length = 531 Score = 59.7 bits (143), Expect = 4e-09 Identities = 34/96 (35%), Positives = 55/96 (57%) Frame = -3 Query: 457 VAAIQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGK 278 V I R D + G VPKGT + + + + + V+ +D ++F+P RF+ R Sbjct: 375 VPFIGRFTEKDYVIDGDIVPKGTTLNLGLLMLGYNDRVF-KDPHKFQPERFD----REKP 429 Query: 277 HPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRF 170 P + FS+GPR+CIGQ FA++E K V++ I++ F Sbjct: 430 GPFEYVPFSAGPRNCIGQKFALLEIKTVVSKIIRNF 465
>CP2DJ_CALJA (O18992) Cytochrome P450 2D19 (EC 1.14.14.1) (CYPIID19) (P450| CM2D-1) Length = 497 Score = 59.7 bits (143), Expect = 4e-09 Identities = 34/90 (37%), Positives = 51/90 (56%) Frame = -3 Query: 427 DLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGKHPNALLSFSS 248 D+EV G +PKGT + ++++ +D+ W E F P F + R K P A L FS+ Sbjct: 381 DIEVQGFLIPKGTTLFTNLSSVLKDEANW-EKPFRFHPEHFLDAQGRFVK-PEAFLPFSA 438 Query: 247 GPRSCIGQNFAMIEAKAVIAMILQRFSFSL 158 G R+C+G+ A +E +LQRFSFS+ Sbjct: 439 GRRACLGEPLARMELFLFFTCLLQRFSFSV 468
>C4AC2_DROME (Q9VMS8) Probable cytochrome P450 4ac2 (EC 1.14.-.-) (CYPIVAC2)| Length = 497 Score = 59.7 bits (143), Expect = 4e-09 Identities = 38/98 (38%), Positives = 56/98 (57%), Gaps = 2/98 (2%) Frame = -3 Query: 457 VAAIQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRF--ENGVTRA 284 V I R+ + V G+ +PK T I I + I RD + + F+P RF EN V R Sbjct: 369 VPFIGRRCVEEGVVNGLIMPKNTQINIHLYEIMRDARHFS-NPKMFQPDRFFPENTVNR- 426 Query: 283 GKHPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRF 170 HP A + FS+G R+CIGQ FA++E K ++A +++ F Sbjct: 427 --HPFAFVPFSAGQRNCIGQKFAILEIKVLLAAVIRNF 462
>CP2D9_MOUSE (P11714) Cytochrome P450 2D9 (EC 1.14.14.1) (CYPIID9)| (P450-16-alpha) (CA) (Testosterone 16-alpha hydroxylase) Length = 504 Score = 59.7 bits (143), Expect = 4e-09 Identities = 36/101 (35%), Positives = 56/101 (55%), Gaps = 4/101 (3%) Frame = -3 Query: 448 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRF--ENGVTRAGKH 275 + R D+EV +PKGT++ ++++ +D+ VW KPLRF E+ + G Sbjct: 377 LPRITSHDIEVQDFLIPKGTILLPNMSSMLKDESVWE------KPLRFHPEHFLDAQGHF 430 Query: 274 --PNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSL 158 P A + FS+G RSC+G+ A +E +LQRFSFS+ Sbjct: 431 VKPEAFMPFSAGRRSCLGEALARMELFLFFTCLLQRFSFSV 471
>CP2DH_MACFA (Q29488) Cytochrome P450 2D17 (EC 1.14.14.1) (CYPIID17)| Length = 497 Score = 59.3 bits (142), Expect = 5e-09 Identities = 33/90 (36%), Positives = 51/90 (56%) Frame = -3 Query: 427 DLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGKHPNALLSFSS 248 D+E+ G +PKGT + ++++ +D+ VW E F P F + K P A L FS+ Sbjct: 381 DIELQGFLIPKGTTLFTNLSSVLKDEAVW-EKPFRFHPEHFLDAQGHFVK-PEAFLPFSA 438 Query: 247 GPRSCIGQNFAMIEAKAVIAMILQRFSFSL 158 G R+C+G+ A +E +LQRFSFS+ Sbjct: 439 GRRACLGEPLARMELFLFFTCLLQRFSFSV 468
>CP136_MYCTU (P95099) Putative cytochrome P450 136 (EC 1.14.-.-)| Length = 492 Score = 59.3 bits (142), Expect = 5e-09 Identities = 39/131 (29%), Positives = 60/131 (45%), Gaps = 5/131 (3%) Frame = -3 Query: 460 PVAAIQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAG 281 PV R+ D E+ G +PKGT + HR E+W D F P RF Sbjct: 365 PVQWAMRQTVRDTELLGYYLPKGTNVIAYPGMNHRLPEIW-TDPLTFDPERFTEPRNEHK 423 Query: 280 KHPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLS-----PKYVHAPMDVITL 116 +H A F G CIG F +E K ++ +L+R+ LS P++ ++ M + Sbjct: 424 RHRYAFTPFGGGVHKCIGMVFDQLEIKTILHRLLRRYRLELSRPDYQPRWDYSAMPI--- 480 Query: 115 RPKFGLPMILK 83 P G+P++L+ Sbjct: 481 -PMDGMPIVLR 490
>CP191_CARAU (P79690) Cytochrome P450 19 type 1 (EC 1.14.14.1) (Brain aromatase)| (CYPXIXA1) (Estrogen synthetase) (P-450AROM) Length = 510 Score = 58.9 bits (141), Expect = 6e-09 Identities = 33/94 (35%), Positives = 52/94 (55%) Frame = -3 Query: 448 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGKHPN 269 I R+A D E+ G +V KGT + + I +H+ + + + NEF FEN V P Sbjct: 371 IMRRALEDDEIDGYRVAKGTNLILNIGRMHKSE--FFQKPNEFNLENFENTVPSRYFQP- 427 Query: 268 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFS 167 F GPR+C+G++ AM+ KA++ +L RF+ Sbjct: 428 ----FGCGPRACVGKHIAMVMTKAILVTLLSRFT 457
>C71AM_ARATH (Q9STL1) Cytochrome P450 71A22 (EC 1.14.-.-)| Length = 490 Score = 58.5 bits (140), Expect = 8e-09 Identities = 30/108 (27%), Positives = 53/108 (49%) Frame = -3 Query: 448 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGKHPN 269 + ++ D+ +G +P GT + I I R+ WG DA +F+P R N H Sbjct: 361 VPHESTQDVRLGDYHIPAGTQVMINAWAIGREAATWGPDAEKFRPERHLNSSVDFRGHNF 420 Query: 268 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDV 125 L+ F +G R C +FA+I + +A ++ R+ + L +Y+ +V Sbjct: 421 ELIPFGAGRRICPAISFAVILIEVTLANLVHRYDWRLPEEYIEDQTNV 468
>C4AD1_DROME (Q9V4T3) Probable cytochrome P450 4ad1 (EC 1.14.-.-) (CYPIVAD1)| Length = 516 Score = 58.5 bits (140), Expect = 8e-09 Identities = 36/97 (37%), Positives = 54/97 (55%), Gaps = 1/97 (1%) Frame = -3 Query: 457 VAAIQRKAGSDLEVGGIKVPK-GTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAG 281 V I R + +++ G KV K TVI IA + +K + +D F+P RFEN G Sbjct: 372 VPLIARTNRNPIDINGTKVAKCTTVIMCLIAMGYNEK--YFDDPCTFRPERFENPTGNVG 429 Query: 280 KHPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRF 170 + FS+GPR CI + FAM + KA+++ +L+RF Sbjct: 430 IEAFKSVPFSAGPRRCIAEKFAMYQMKALLSQLLRRF 466
>CP2DA_RAT (P12939) Cytochrome P450 2D10 (EC 1.14.14.1) (CYPIID10) (P450-DB5)| (P450-CMF1B) (Debrisoquine 4-hydroxylase) Length = 504 Score = 58.5 bits (140), Expect = 8e-09 Identities = 33/97 (34%), Positives = 52/97 (53%) Frame = -3 Query: 448 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGKHPN 269 + R D+EV +PKGT + I ++++ +D+ VW E F P F + KH Sbjct: 377 LPRITSCDIEVQDFVIPKGTTLIINLSSVLKDETVW-EKPLRFHPEHFLDAQGNFVKH-E 434 Query: 268 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSL 158 A + FS+G R+C+G+ A +E +LQ FSFS+ Sbjct: 435 AFMPFSAGRRACLGEPLARMELFLFFTCLLQHFSFSV 471
>C83B1_ARATH (O65782) Cytochrome P450 83B1 (EC 1.14.-.-)| Length = 499 Score = 58.2 bits (139), Expect = 1e-08 Identities = 39/116 (33%), Positives = 59/116 (50%), Gaps = 6/116 (5%) Frame = -3 Query: 448 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFEN---GVTRAGK 278 + R+ +D ++GG +P T+I + + RD WG++ NEF P RF N GV G+ Sbjct: 368 LHRETIADAKIGGYDIPAKTIIQVNAWAVSRDTAAWGDNPNEFIPERFMNEHKGVDFKGQ 427 Query: 277 HPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYV---HAPMDVIT 119 LL F SG R C + + + A +L +F +SL PK + MDV+T Sbjct: 428 -DFELLPFGSGRRMCPAMHLGIAMVEIPFANLLYKFDWSL-PKGIKPEDIKMDVMT 481
>CP4G1_DROME (Q9V3S0) Cytochrome P450 4g1 (EC 1.14.-.-) (CYPIVG1)| Length = 556 Score = 58.2 bits (139), Expect = 1e-08 Identities = 32/103 (31%), Positives = 57/103 (55%), Gaps = 6/103 (5%) Frame = -3 Query: 460 PVAAIQRKAGSDLEV--GGIKVPKGTVITIPIATIHRDKEVWGE----DANEFKPLRFEN 299 PV I R+ DL++ G VPKGT + + +HR +++ D + F P R N Sbjct: 422 PVPLIARRLDYDLKLASGPYTVPKGTTVIVLQYCVHRRPDIYPNPTKFDPDNFLPERMAN 481 Query: 298 GVTRAGKHPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRF 170 +H + + FS+GPRSC+G+ +AM++ K +++ I++ + Sbjct: 482 ------RHYYSFIPFSAGPRSCVGRKYAMLKLKVLLSTIVRNY 518
>CP2DS_MESAU (Q9QUJ1) Cytochrome P450 2D28 (EC 1.14.14.-) (CYPIID28)| Length = 500 Score = 58.2 bits (139), Expect = 1e-08 Identities = 40/117 (34%), Positives = 60/117 (51%) Frame = -3 Query: 427 DLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGKHPNALLSFSS 248 D+EV G +PKGT + ++++ +D+ VW E F P F + K A + FS+ Sbjct: 384 DIEVQGFLIPKGTTLITNLSSVLKDETVW-EKPLHFHPEHFLDAQGCFVKQ-EAFMPFSA 441 Query: 247 GPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITLRPKFGLPMILKSP 77 G R+C+G+ A +E +LQRFSFS+ P P D + L +LKSP Sbjct: 442 GRRACLGEPLARMELFLFFTCLLQRFSFSV-PAGQPRPSDHVVLG-------VLKSP 490
>CP2DK_MESAU (Q9QYG5) Cytochrome P450 2D20 (EC 1.14.14.-) (CYPIID20)| Length = 500 Score = 58.2 bits (139), Expect = 1e-08 Identities = 33/90 (36%), Positives = 51/90 (56%) Frame = -3 Query: 427 DLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGKHPNALLSFSS 248 D+EV G +PKGT + ++++ +D+ VW E F P F + R K A + FS+ Sbjct: 384 DVEVQGFLIPKGTTLIPNLSSVLKDETVW-EKPLHFHPEHFLDAQGRFVKQ-EAFMPFSA 441 Query: 247 GPRSCIGQNFAMIEAKAVIAMILQRFSFSL 158 G R+C+G+ A +E +LQRFSFS+ Sbjct: 442 GRRACLGEPLARMELFLFFTCLLQRFSFSV 471
>C6A18_DROME (Q9VB31) Probable cytochrome P450 6a18 (EC 1.14.-.-) (CYPVIA18)| Length = 507 Score = 58.2 bits (139), Expect = 1e-08 Identities = 31/82 (37%), Positives = 48/82 (58%), Gaps = 1/82 (1%) Frame = -3 Query: 403 VPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGKHPN-ALLSFSSGPRSCIG 227 + G + IP + IH D ++ E NEF+P RF + K P+ A L F GPR+CIG Sbjct: 397 IEAGQSVIIPSSAIHHDPSIYPEP-NEFRPERFSP--EESAKRPSVAWLPFGEGPRNCIG 453 Query: 226 QNFAMIEAKAVIAMILQRFSFS 161 F ++A+ +AM+++ F+FS Sbjct: 454 LRFGQMQARIGLAMLIKNFTFS 475
>CP17A_PANTR (Q8HYN1) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 508 Score = 57.8 bits (138), Expect = 1e-08 Identities = 37/104 (35%), Positives = 55/104 (52%), Gaps = 3/104 (2%) Frame = -3 Query: 460 PVAA--IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTR 287 PVA I KA D +G V KGT + I + +H +++ W + ++F P RF N Sbjct: 365 PVAPMLIPHKANVDSSIGEFAVDKGTQVIINLWALHHNEKEWHQP-DQFMPERFLNPAGT 423 Query: 286 AGKHPN-ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSL 158 P+ + L F +GPRSCIG+ A E ++A +LQRF + Sbjct: 424 QLISPSVSYLPFGAGPRSCIGEILARQELFLIMAWLLQRFDLEV 467
>CP17A_HUMAN (P05093) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-monooxygenase) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 508 Score = 57.8 bits (138), Expect = 1e-08 Identities = 37/104 (35%), Positives = 55/104 (52%), Gaps = 3/104 (2%) Frame = -3 Query: 460 PVAA--IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTR 287 PVA I KA D +G V KGT + I + +H +++ W + ++F P RF N Sbjct: 365 PVAPMLIPHKANVDSSIGEFAVDKGTEVIINLWALHHNEKEWHQP-DQFMPERFLNPAGT 423 Query: 286 AGKHPN-ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSL 158 P+ + L F +GPRSCIG+ A E ++A +LQRF + Sbjct: 424 QLISPSVSYLPFGAGPRSCIGEILARQELFLIMAWLLQRFDLEV 467
>C6A17_DROME (Q9V770) Probable cytochrome P450 6a17 (EC 1.14.-.-) (CYPVIA17)| Length = 501 Score = 57.8 bits (138), Expect = 1e-08 Identities = 32/94 (34%), Positives = 52/94 (55%) Frame = -3 Query: 403 VPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGKHPNALLSFSSGPRSCIGQ 224 + KGT++ IP IH D +++ E FKP RF + A + L F GPR+CIG Sbjct: 390 IAKGTIVVIPALGIHYDPDIYPEP-EIFKPERFTDEEI-AARPSCTWLPFGEGPRNCIGL 447 Query: 223 NFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVI 122 F M++ +A +++ + FS+SP+ PM ++ Sbjct: 448 RFGMMQTCVGLAYLIRGYKFSVSPE-TQIPMKIV 480
>CP1A1_MOUSE (P00184) Cytochrome P450 1A1 (EC 1.14.14.1) (CYPIA1) (P450-P1)| Length = 524 Score = 57.4 bits (137), Expect = 2e-08 Identities = 33/113 (29%), Positives = 56/113 (49%), Gaps = 1/113 (0%) Frame = -3 Query: 427 DLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGKHPNALLS-FS 251 D + G +PKG + + ++ D+E+WG D NEF+P RF K + ++ F Sbjct: 397 DTSLNGFYIPKGCCVFVNQWQVNHDRELWG-DPNEFRPERFLTPSGTLDKRLSEKVTLFG 455 Query: 250 SGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITLRPKFGLPM 92 G R CIG+ E +A++LQ+ F +SP + + + P +GL + Sbjct: 456 LGKRKCIGETIGRSEVFLFLAILLQQIEFKVSPG------EKVDMTPTYGLTL 502
>CP46A_MOUSE (Q9WVK8) Cytochrome p450 46A1 (EC 1.14.13.98) (Cholesterol| 24-hydroxylase) (CH24H) Length = 500 Score = 57.4 bits (137), Expect = 2e-08 Identities = 38/103 (36%), Positives = 50/103 (48%) Frame = -3 Query: 418 VGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGKHPNALLSFSSGPR 239 + G++VP T + + R + + ED F P RF G A K FS G R Sbjct: 380 IDGVRVPGNTPLLFSTYVMGR-MDTYFEDPLTFNPDRFGPG---APKPRFTYFPFSLGHR 435 Query: 238 SCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITLRP 110 SCIGQ FA +E K V+A +LQR F L P + TL+P Sbjct: 436 SCIGQQFAQMEVKVVMAKLLQRIEFRLVPGQRFGLQEQATLKP 478
>CP46A_HUMAN (Q9Y6A2) Cytochrome p450 46A1 (EC 1.14.13.98) (Cholesterol| 24-hydroxylase) (CH24H) Length = 500 Score = 57.4 bits (137), Expect = 2e-08 Identities = 38/103 (36%), Positives = 50/103 (48%) Frame = -3 Query: 418 VGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGKHPNALLSFSSGPR 239 + G++VP T + + R + + ED F P RF G A K FS G R Sbjct: 380 IDGVRVPGNTPLLFSTYVMGR-MDTYFEDPLTFNPDRFGPG---APKPRFTYFPFSLGHR 435 Query: 238 SCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITLRP 110 SCIGQ FA +E K V+A +LQR F L P + TL+P Sbjct: 436 SCIGQQFAQMEVKVVMAKLLQRLEFRLVPGQRFGLQEQATLKP 478
>CP17A_PAPHU (Q9GLD2) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 508 Score = 57.4 bits (137), Expect = 2e-08 Identities = 37/104 (35%), Positives = 55/104 (52%), Gaps = 3/104 (2%) Frame = -3 Query: 460 PVAA--IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTR 287 PVA I KA D +G V KGT + I + +H +++ W + ++F P RF N Sbjct: 365 PVAPMLIPHKANVDSSIGEFAVDKGTHVIINLWALHHNEKEWHQP-DQFMPERFLNPAGT 423 Query: 286 AGKHPN-ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSL 158 P+ + L F +GPRSCIG+ A E ++A +LQRF + Sbjct: 424 QLISPSLSYLPFGAGPRSCIGEILARQELFLIMAWLLQRFDLEV 467
>CP17A_PAPCY (Q8HYN0) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 508 Score = 57.4 bits (137), Expect = 2e-08 Identities = 37/104 (35%), Positives = 55/104 (52%), Gaps = 3/104 (2%) Frame = -3 Query: 460 PVAA--IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTR 287 PVA I KA D +G V KGT + I + +H +++ W + ++F P RF N Sbjct: 365 PVAPMLIPHKANVDSSIGEFAVDKGTHVIINLWALHHNEKEWHQP-DQFMPERFLNPAGT 423 Query: 286 AGKHPN-ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSL 158 P+ + L F +GPRSCIG+ A E ++A +LQRF + Sbjct: 424 QLISPSLSYLPFGAGPRSCIGEILARQELFLIMAWLLQRFDLEV 467
>CP17A_MACMU (Q8HYM9) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 508 Score = 57.4 bits (137), Expect = 2e-08 Identities = 37/104 (35%), Positives = 55/104 (52%), Gaps = 3/104 (2%) Frame = -3 Query: 460 PVAA--IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTR 287 PVA I KA D +G V KGT + I + +H +++ W + ++F P RF N Sbjct: 365 PVAPMLIPHKANVDSSIGEFAVDKGTHVIINLWALHHNEKEWHQP-DQFMPERFLNPAGT 423 Query: 286 AGKHPN-ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSL 158 P+ + L F +GPRSCIG+ A E ++A +LQRF + Sbjct: 424 QLISPSLSYLPFGAGPRSCIGEILARQELFLIMAWLLQRFDLEV 467
>CP17A_MACFA (Q2XVA1) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 508 Score = 57.4 bits (137), Expect = 2e-08 Identities = 37/104 (35%), Positives = 55/104 (52%), Gaps = 3/104 (2%) Frame = -3 Query: 460 PVAA--IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTR 287 PVA I KA D +G V KGT + I + +H +++ W + ++F P RF N Sbjct: 365 PVAPMLIPHKANVDSSIGEFAVDKGTHVIINLWALHHNEKEWHQP-DQFMPERFLNPAGT 423 Query: 286 AGKHPN-ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSL 158 P+ + L F +GPRSCIG+ A E ++A +LQRF + Sbjct: 424 QLISPSLSYLPFGAGPRSCIGEILARQELFLIMAWLLQRFDLEV 467
>C76C3_ARATH (O64638) Cytochrome P450 76C3 (EC 1.14.-.-)| Length = 515 Score = 57.4 bits (137), Expect = 2e-08 Identities = 39/119 (32%), Positives = 58/119 (48%) Frame = -3 Query: 448 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGKHPN 269 I RK+ SD+++ G VPK T + + + I RD VW E+ +F+P RF T Sbjct: 381 IPRKSESDVQIMGFLVPKNTQVVVNVWAIGRDASVW-ENPMKFEPERFLLRETDVKGRDF 439 Query: 268 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITLRPKFGLPM 92 L+ F SG R C G + A+ V+A +L F + L V +D + FGL + Sbjct: 440 ELIPFGSGRRMCPGISMALKTMHMVLASLLYSFDWKLQNGVVPGNID---MSETFGLTL 495
>CP2J6_MOUSE (O54750) Cytochrome P450 2J6 (EC 1.14.14.1) (CYPIIJ6) (Arachidonic| acid epoxygenase) Length = 501 Score = 57.4 bits (137), Expect = 2e-08 Identities = 34/108 (31%), Positives = 54/108 (50%), Gaps = 7/108 (6%) Frame = -3 Query: 448 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRF-ENGVTRAGKHP 272 + R+ D + G +PKGT++ + +HRD + W + F P F ENG K Sbjct: 379 VPREVAMDTNLNGFHLPKGTMVLTNLTALHRDPKEWA-TPDVFNPEHFLENG---QFKKR 434 Query: 271 NALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFS------LSPKY 146 + L FS G R+C+G+ A E ++Q+F+F+ LSPK+ Sbjct: 435 ESFLPFSMGKRACLGEQLARSELFIFFTSLMQKFTFNPPINEKLSPKF 482
>CP2DF_CANFA (Q29473) Cytochrome P450 2D15 (EC 1.14.14.1) (CYPIID15) (P450 DUT2)| Length = 499 Score = 57.0 bits (136), Expect = 2e-08 Identities = 32/90 (35%), Positives = 50/90 (55%) Frame = -3 Query: 427 DLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGKHPNALLSFSS 248 D EV G +PKGT + ++++ +D++VW + F P F + KH A + FS+ Sbjct: 383 DTEVQGFLIPKGTTLITNLSSVLKDEKVWKKPFR-FYPEHFLDAQGHFVKH-EAFMPFSA 440 Query: 247 GPRSCIGQNFAMIEAKAVIAMILQRFSFSL 158 G R C+G+ A +E +LQRFSFS+ Sbjct: 441 GRRVCLGEPLARMELFLFFTCLLQRFSFSV 470
>CP52Q_CANMA (Q12587) Cytochrome P450 52C2 (EC 1.14.14.-) (CYPLIIC2)| (Alkane-inducible P450-ALK6-A) Length = 510 Score = 57.0 bits (136), Expect = 2e-08 Identities = 33/96 (34%), Positives = 50/96 (52%) Frame = -3 Query: 409 IKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGKHPNALLSFSSGPRSCI 230 I V KG + P+ +R ++ +G EF P R+ + G A + FS+GPR C+ Sbjct: 403 ILVKKGDQVLFPLYASNRQEKYFGRKPEEFIPERWRDLPKTGGP---AFMPFSTGPRMCL 459 Query: 229 GQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVI 122 GQ FA+IEA V ++Q FS S +AP ++ Sbjct: 460 GQQFALIEASYVTIRLVQTFSKLKSHSLEYAPKRLV 495
>CP6A2_DROME (P33270) Cytochrome P450 6a2 (EC 1.14.-.-) (CYPVIA2) (P450-B1)| Length = 506 Score = 57.0 bits (136), Expect = 2e-08 Identities = 35/103 (33%), Positives = 54/103 (52%), Gaps = 3/103 (2%) Frame = -3 Query: 457 VAAIQRKAGSDLEVGG---IKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTR 287 V ++RKA +D V G + + KGT + IP HRD++++ + F P RF Sbjct: 376 VPHLERKALNDYVVPGHEKLVIEKGTQVIIPACAYHRDEDLY-PNPETFDPERFSPEKV- 433 Query: 286 AGKHPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSL 158 A + L F GPR+CIG F ++A+ +A I+ RF S+ Sbjct: 434 AARESVEWLPFGDGPRNCIGMRFGQMQARIGLAQIISRFRVSV 476
>CP2R1_HUMAN (Q6VVX0) Cytochrome P450 2R1 (EC 1.14.14.-) (Vitamin D| 25-hydroxylase) Length = 501 Score = 57.0 bits (136), Expect = 2e-08 Identities = 35/113 (30%), Positives = 58/113 (51%), Gaps = 1/113 (0%) Frame = -3 Query: 427 DLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGKHPNALLSFSS 248 D V G +PKGT + + ++H D++ W D F P RF + K AL+ FS Sbjct: 386 DAVVRGYSIPKGTTVITNLYSVHFDEKYW-RDPEVFHPERFLDSSGYFAKK-EALVPFSL 443 Query: 247 GPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVI-TLRPKFGLPM 92 G R C+G++ A +E +LQRF ++H P +++ L+P+ G+ + Sbjct: 444 GRRHCLGEHLARMEMFLFFTALLQRF-------HLHFPHELVPDLKPRLGMTL 489
>CP1A1_RABIT (P05176) Cytochrome P450 1A1 (EC 1.14.14.1) (CYPIA1) (P450 isozyme| 6) (P-450 PHPAH1) (P450 LM6) Length = 518 Score = 57.0 bits (136), Expect = 2e-08 Identities = 38/116 (32%), Positives = 56/116 (48%), Gaps = 4/116 (3%) Frame = -3 Query: 427 DLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGKHPNAL----L 260 D +GG +PKG + + + D E+WG D F+P RF +T +G AL L Sbjct: 397 DTSLGGFYIPKGRCVFVNQWQNNHDPELWG-DPEAFRPERF---LTPSGAVDKALTEKVL 452 Query: 259 SFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITLRPKFGLPM 92 F G R CIG+ +E +A +LQ+ FS+SP + + P +GL M Sbjct: 453 LFGLGKRKCIGETIGRLEVFLFLATLLQQVEFSVSPG------TTVDMTPIYGLTM 502
>CP120_SYNY3 (Q59990) Putative cytochrome P450 120 (EC 1.14.-.-)| Length = 444 Score = 56.6 bits (135), Expect = 3e-08 Identities = 37/127 (29%), Positives = 60/127 (47%) Frame = -3 Query: 460 PVAAIQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAG 281 PV R+ D + G PKG +++ I+ H D +++ D +F P RF + Sbjct: 317 PVGGGFRELIQDCQFQGFHFPKGWLVSYQISQTHADPDLY-PDPEKFDPERFTPDGSATH 375 Query: 280 KHPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITLRPKFG 101 P A + F G R C+G+ FA +E K ++Q+F ++L P + + RPK Sbjct: 376 NPPFAHVPFGGGLRECLGKEFARLEMKLFATRLIQQFDWTLLPGQNLELVVTPSPRPKDN 435 Query: 100 LPMILKS 80 L + L S Sbjct: 436 LRVKLHS 442
>C6A23_DROME (Q9V771) Probable cytochrome P450 6a23 (EC 1.14.-.-) (CYPVIA23)| Length = 502 Score = 56.6 bits (135), Expect = 3e-08 Identities = 38/110 (34%), Positives = 57/110 (51%) Frame = -3 Query: 403 VPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGKHPNALLSFSSGPRSCIGQ 224 + KGT + IP IH D E++ E +FKP RF + A + L F GPR+CIG Sbjct: 391 IAKGTTVVIPALGIHYDPEIYPEP-EKFKPERFTDEAI-AARPSCTWLPFGEGPRNCIGL 448 Query: 223 NFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITLRPKFGLPMILKSPE 74 F +++A +A +++ + FS+S + PM KF + IL S E Sbjct: 449 RFGLMQACVGLAYLIRGYKFSVSTE-TQIPM-------KFVVKSILLSAE 490
>C28D1_DROME (Q9VMT5) Probable cytochrome P450 28d1 (EC 1.14.-.-) (CYPXXVIIID1)| Length = 502 Score = 56.6 bits (135), Expect = 3e-08 Identities = 28/89 (31%), Positives = 46/89 (51%), Gaps = 2/89 (2%) Frame = -3 Query: 409 IKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFEN--GVTRAGKHPNALLSFSSGPRS 236 +K+ G V+ IP+ +H D + + E+ FKP RF N G + + F GPR Sbjct: 387 VKLRPGDVVIIPVNALHHDPQYY-EEPQSFKPERFLNINGGAKKYRDQGLFFGFGDGPRI 445 Query: 235 CIGQNFAMIEAKAVIAMILQRFSFSLSPK 149 C G F++ + KA + I++ F ++PK Sbjct: 446 CPGMRFSLTQIKAALVEIVRNFDIKVNPK 474
>CP304_DROME (Q9VG17) Probable cytochrome P450 304a1 (EC 1.14.-.-) (CYPCCCIVA1)| Length = 510 Score = 56.6 bits (135), Expect = 3e-08 Identities = 31/99 (31%), Positives = 47/99 (47%) Frame = -3 Query: 448 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGKHPN 269 + KA D E+ G ++PK T++ + H D +W D +F+P RF + + + Sbjct: 384 VPHKALEDTELLGYRIPKDTIVVPSLYAFHSDARIW-SDPEQFRPERFLDADGKLCLKLD 442 Query: 268 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSP 152 L F +G R C G+ FA V A + Q F F L P Sbjct: 443 VSLPFGAGKRLCAGETFARNMLFLVTATMCQHFDFVLGP 481
>CP2DE_BOVIN (Q01361) Cytochrome P450 2D14 (EC 1.14.14.1) (CYPIID14) (Fragment)| Length = 487 Score = 56.6 bits (135), Expect = 3e-08 Identities = 31/90 (34%), Positives = 50/90 (55%) Frame = -3 Query: 427 DLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGKHPNALLSFSS 248 D+EV G +PKGT + ++++ +D+ VW + F P F + R K A + FS+ Sbjct: 371 DIEVQGFHIPKGTTLITNLSSVLKDETVW-QKPFRFHPEHFLDAQGRFVKQ-EAFIPFSA 428 Query: 247 GPRSCIGQNFAMIEAKAVIAMILQRFSFSL 158 G R+C+G+ A +E +LQ FSFS+ Sbjct: 429 GRRACLGEPLARMELFLFFTSLLQHFSFSV 458
>CP2DQ_RAT (P10634) Cytochrome P450 2D26 (EC 1.14.14.1) (CYPIID26) (P450-DB2)| (P450-CMF2) (Debrisoquine 4-hydroxylase) Length = 500 Score = 56.6 bits (135), Expect = 3e-08 Identities = 32/97 (32%), Positives = 51/97 (52%) Frame = -3 Query: 448 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGKHPN 269 I D++ G +PKGT + ++++ +D+ VW E F P F + KH Sbjct: 377 IPHMTSRDIKFQGFLIPKGTTLIPNLSSVLKDETVW-EKPLRFHPEHFLDAQGNFVKH-E 434 Query: 268 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSL 158 A + FS+G R+C+G+ A +E +LQRFSFS+ Sbjct: 435 AFMPFSAGRRACLGEPLARMELFLFFTCLLQRFSFSV 471
>C76B1_HELTU (O23976) Cytochrome P450 76B1 (EC 1.14.-.-) (7-ethoxycoumarin| O-deethylase) (ECOD) (Phenylurea dealkylase) Length = 490 Score = 56.6 bits (135), Expect = 3e-08 Identities = 36/124 (29%), Positives = 56/124 (45%) Frame = -3 Query: 448 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGKHPN 269 + RK + +E+ G +P GT++ + I RD VW +D+ EFKP RF H Sbjct: 362 LPRKVVTQVELSGYTIPAGTLVFVNAWAIGRDPTVW-DDSLEFKPQRFLESRLDVRGHDF 420 Query: 268 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITLRPKFGLPMI 89 L+ F +G R C G A ++ +L F + + K P DV+ + K G + Sbjct: 421 DLIPFGAGRRICPGIPLATRMVPIMLGSLLNNFDWKIDTK---VPYDVLDMTEKNGTTIS 477 Query: 88 LKSP 77 P Sbjct: 478 KAKP 481
>CP2DA_MOUSE (P24456) Cytochrome P450 2D10 (EC 1.14.14.1) (CYPIID10)| (P450-16-alpha) (P450CB) (Testosterone 16-alpha hydroxylase) Length = 504 Score = 56.6 bits (135), Expect = 3e-08 Identities = 34/101 (33%), Positives = 55/101 (54%), Gaps = 4/101 (3%) Frame = -3 Query: 448 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRF--ENGVTRAGKH 275 + R D+EV +PKG+++ ++++ +D+ VW KPLRF E+ + G Sbjct: 377 LPRITSRDIEVQDFLIPKGSILIPNMSSVLKDETVWE------KPLRFHPEHFLDAQGHF 430 Query: 274 --PNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSL 158 P A + FS+G RSC+G+ A +E +LQ FSFS+ Sbjct: 431 VKPEAFMPFSAGRRSCLGEPLARMELFLFFTCLLQHFSFSV 471
>CP2DP_PIG (O46658) Cytochrome P450 2D25 (EC 1.14.14.-) (CYPIID25) (Vitamin| D(3) 25-hydroxylase) Length = 499 Score = 56.2 bits (134), Expect = 4e-08 Identities = 32/90 (35%), Positives = 49/90 (54%) Frame = -3 Query: 427 DLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGKHPNALLSFSS 248 D+EV G +PKGT + + ++ +D+ VW + F P F + R K A + FS+ Sbjct: 383 DIEVQGFLIPKGTTLITNLTSVLKDETVWKKPFR-FYPEHFLDAQGRFTKQ-EAFMPFSA 440 Query: 247 GPRSCIGQNFAMIEAKAVIAMILQRFSFSL 158 G RSC+G+ A +E +LQ FSFS+ Sbjct: 441 GRRSCLGEPLARMELFLFFTTLLQAFSFSV 470
>CP2J3_RAT (P51590) Cytochrome P450 2J3 (EC 1.14.14.1) (CYPIIJ3)| Length = 502 Score = 56.2 bits (134), Expect = 4e-08 Identities = 32/96 (33%), Positives = 49/96 (51%), Gaps = 1/96 (1%) Frame = -3 Query: 448 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRF-ENGVTRAGKHP 272 + R+ D + G +PKGT+I + +HRD + W + F P F ENG K Sbjct: 380 VPREVAVDTYLAGFNLPKGTMILTNLTALHRDPKEWA-TPDTFNPEHFLENG---QFKKR 435 Query: 271 NALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSF 164 + L FS G R+C+G+ A E I ++Q+F+F Sbjct: 436 ESFLPFSMGKRACLGEQLARSELFIFITSLIQKFTF 471
>CP6A1_MUSDO (P13527) Cytochrome P450 6A1 (EC 1.14.14.1) (CYPVIA1)| Length = 509 Score = 56.2 bits (134), Expect = 4e-08 Identities = 29/93 (31%), Positives = 53/93 (56%) Frame = -3 Query: 403 VPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGKHPNALLSFSSGPRSCIGQ 224 +PKGT++ IP+ IH D E++ + EF P RF + + + L F GPR+CIG Sbjct: 395 LPKGTLVFIPVLGIHYDPELY-PNPEEFDPERFSPEMVKQRDSVD-WLGFGDGPRNCIGM 452 Query: 223 NFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDV 125 F ++++ +A++++ F F++ + PM + Sbjct: 453 RFGKMQSRLGLALVIRHFRFTVCSR-TDIPMQI 484
>C75A4_GENTR (Q96581) Flavonoid 3',5'-hydroxylase (EC 1.14.13.88) (F3'5'H)| (Cytochrome P450 75A4) Length = 516 Score = 56.2 bits (134), Expect = 4e-08 Identities = 30/93 (32%), Positives = 48/93 (51%), Gaps = 4/93 (4%) Frame = -3 Query: 424 LEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENG----VTRAGKHPNALLS 257 ++V G +PKGT + + I I RD VWG++ NEF P RF G + G H L+ Sbjct: 387 VDVNGYYIPKGTRLNVNIWAIGRDPSVWGDNPNEFDPERFLYGRNAKIDPRGNH-FELIP 445 Query: 256 FSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSL 158 F +G R C G ++ + ++ ++ F + L Sbjct: 446 FGAGRRICAGTRMGILLVEYILGTLVHSFDWKL 478
>CP1A2_RABIT (P00187) Cytochrome P450 1A2 (EC 1.14.14.1) (CYPIA2) (P450 isozyme| 4) (P450-PM4) (P450 LM4) Length = 515 Score = 56.2 bits (134), Expect = 4e-08 Identities = 43/117 (36%), Positives = 57/117 (48%), Gaps = 5/117 (4%) Frame = -3 Query: 427 DLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGKHPNALLS--- 257 D + G +PK I I I+ D ++WG D EF+P RF +T G N LS Sbjct: 392 DTTLNGFHIPKECCIFINQWQINHDPQLWG-DPEEFRPERF---LTADGAAINKPLSEKV 447 Query: 256 --FSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITLRPKFGLPM 92 F G R CIG+ A E +A++LQR FS+ P P+D L P +GL M Sbjct: 448 TLFGLGKRRCIGETLARWEVFLFLAILLQRLEFSVPP---GVPVD---LTPIYGLTM 498
>CP19A_ICTPU (Q92111) Cytochrome P450 19A1 (EC 1.14.14.1) (Aromatase) (CYPXIX)| (Estrogen synthetase) (P-450AROM) Length = 524 Score = 55.8 bits (133), Expect = 5e-08 Identities = 35/92 (38%), Positives = 51/92 (55%) Frame = -3 Query: 442 RKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGKHPNAL 263 R+A D + G +VP+GT I + + +HR E + + A +F F V P Sbjct: 395 RRALDDDVIEGFRVPRGTNIILNVGRMHRS-EFYPKPA-DFSLDNFNKPVPSRFFQP--- 449 Query: 262 LSFSSGPRSCIGQNFAMIEAKAVIAMILQRFS 167 F SGPRSC+G++ AM+ KAV+ M+L RFS Sbjct: 450 --FGSGPRSCVGKHIAMVMMKAVLLMVLSRFS 479
>CP313_DROME (Q9VHP4) Probable cytochrome P450 313b1 (EC 1.14.-.-)| (CYPCCCXIIIB1) Length = 502 Score = 55.5 bits (132), Expect = 7e-08 Identities = 32/104 (30%), Positives = 52/104 (50%), Gaps = 4/104 (3%) Frame = -3 Query: 460 PVAAIQRKAGSDLEV----GGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGV 293 PV + R A D+++ G +P+GT I I I + RD+ VWG + + P G+ Sbjct: 371 PVPMVLRSADQDIQLKRGDGEFLIPRGTQIGIDIYNMQRDERVWGPLSRTYNP-DAHFGL 429 Query: 292 TRAGKHPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFS 161 +H A + F+ G R CIG +A + K ++A I + + S Sbjct: 430 DSPQRHAFAFVPFTKGLRMCIGYRYAQMLMKLLLARIFRSYRIS 473
>CP19A_ORENI (P70091) Cytochrome P450 19A1 (EC 1.14.14.1) (Aromatase) (CYPXIX)| (Estrogen synthetase) (P-450AROM) Length = 522 Score = 55.5 bits (132), Expect = 7e-08 Identities = 32/92 (34%), Positives = 51/92 (55%) Frame = -3 Query: 442 RKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGKHPNAL 263 R+A SD + G ++ KGT I + +HR + + N+F FEN V R P Sbjct: 384 RRALSDDIIEGYRISKGTNIILNTGRMHRTE--FFLKGNQFNLEHFENNVPR----PPTF 437 Query: 262 LSFSSGPRSCIGQNFAMIEAKAVIAMILQRFS 167 F SGPR+CIG++ AM+ K+++ +L ++S Sbjct: 438 QPFGSGPRACIGKHMAMVMMKSILVTLLSQYS 469
>CP6A8_DROME (Q27593) Cytochrome P450 6a8 (EC 1.14.-.-) (CYPVIA8)| Length = 506 Score = 55.5 bits (132), Expect = 7e-08 Identities = 30/85 (35%), Positives = 47/85 (55%) Frame = -3 Query: 403 VPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGKHPNALLSFSSGPRSCIGQ 224 + G + IP + IH D ++ E EF+P RF + AG+ A L F GPR+CIG Sbjct: 397 IEAGQSVIIPSSAIHHDPSIYPEPF-EFRPERFSPEES-AGRPSVAWLPFGDGPRNCIGL 454 Query: 223 NFAMIEAKAVIAMILQRFSFSLSPK 149 F ++A+ +A++++ F FS K Sbjct: 455 RFGQMQARIGLALLIRNFKFSTCSK 479
>C71AE_ARATH (P58045) Cytochrome P450 71A14 (EC 1.14.-.-)| Length = 497 Score = 55.5 bits (132), Expect = 7e-08 Identities = 36/124 (29%), Positives = 55/124 (44%) Frame = -3 Query: 448 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGKHPN 269 + R+ D+++ G + GT + I I RD WG DA EF+P R + + Sbjct: 369 VPRELSEDIKLKGYDIAAGTQVIINAWAIQRDTMTWGIDAEEFRPERHLDSLVDFRGTNF 428 Query: 268 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITLRPKFGLPMI 89 + F SG R C G FAM + +A ++ RF++ + V D L GL + Sbjct: 429 EFIPFGSGRRICPGIGFAMALVEVTLANLVNRFNWRME---VQHSGDEYDLAESTGLDVC 485 Query: 88 LKSP 77 K P Sbjct: 486 RKFP 489
>C71AC_ARATH (O49340) Cytochrome P450 71A12 (EC 1.14.-.-)| Length = 497 Score = 55.5 bits (132), Expect = 7e-08 Identities = 33/96 (34%), Positives = 49/96 (51%), Gaps = 1/96 (1%) Frame = -3 Query: 448 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLR-FENGVTRAGKHP 272 + R D++V G + GT + I I RD +WG DA EFKP R ++ + GK Sbjct: 368 LPRLLSEDVKVKGYNIAAGTEVIINAWAIQRDPAIWGPDAEEFKPERHLDSTLDYHGKDL 427 Query: 271 NALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSF 164 N + F SG R C G N A+ + +A ++ RF + Sbjct: 428 N-FIPFGSGRRICPGINLALGLVEVTVANLVGRFDW 462
>C71BC_ARATH (Q9ZU07) Cytochrome P450 71B12 (EC 1.14.-.-)| Length = 496 Score = 55.5 bits (132), Expect = 7e-08 Identities = 41/124 (33%), Positives = 55/124 (44%) Frame = -3 Query: 448 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGKHPN 269 I R+A D+++GG +PK T I + I IHR+ VW +D F P RF + Sbjct: 366 IPREASKDVKIGGYNIPKKTWIHVNIWAIHRNPNVW-KDPEAFIPERFMDSQIDYKGLNF 424 Query: 268 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITLRPKFGLPMI 89 LL F SG R C G M + +L RF + L A +D L +GL Sbjct: 425 ELLPFGSGRRICPGIGMGMALVHLTLINLLYRFDWKLPEGMKVADVD---LEESYGLVCP 481 Query: 88 LKSP 77 K P Sbjct: 482 KKIP 485
>C76C4_ARATH (O64635) Cytochrome P450 76C4 (EC 1.14.-.-)| Length = 511 Score = 55.1 bits (131), Expect = 9e-08 Identities = 35/108 (32%), Positives = 51/108 (47%) Frame = -3 Query: 448 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGKHPN 269 + RKA SD+EV G VPK T + + + I RD VW E+ ++F+P RF Sbjct: 380 VPRKAESDVEVLGFMVPKDTQVLVNVWAIGRDPSVW-ENPSQFEPERFMGKDIDVKGRDY 438 Query: 268 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDV 125 L F G R C G A+ ++A +L F + L V +D+ Sbjct: 439 ELTPFGGGRRICPGLPLAVKTVSLMLASLLYSFDWKLPNGVVSEDLDM 486
>CP2J1_RABIT (P52786) Cytochrome P450 2J1 (EC 1.14.14.1) (CYPIIJ1) (P-450IB)| Length = 500 Score = 55.1 bits (131), Expect = 9e-08 Identities = 31/96 (32%), Positives = 48/96 (50%), Gaps = 1/96 (1%) Frame = -3 Query: 448 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRF-ENGVTRAGKHP 272 + R+ D + G +PKGTV+ + +H+D E W + F P F ENG K Sbjct: 378 VPREVTVDTTLAGYHLPKGTVVLTNLTALHKDPEEWA-TPDTFNPEHFLENG---QFKKK 433 Query: 271 NALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSF 164 A + FS G R+C+G+ A E ++Q+F+F Sbjct: 434 EAFIPFSIGKRACLGEQLAKSELFIFFTSLMQKFTF 469
>CP6D5_DROME (Q9VFP1) Probable cytochrome P450 6d5 (EC 1.14.-.-) (CYPVID5)| Length = 508 Score = 55.1 bits (131), Expect = 9e-08 Identities = 40/111 (36%), Positives = 54/111 (48%), Gaps = 5/111 (4%) Frame = -3 Query: 403 VPKGTVITIPIATIHRDKEVWGEDANEFKPLRF-ENG--VTRAGKHPNALLSFSSGPRSC 233 + KGT I I + +HRD+E + D +KP R+ ENG T+A A L F GPR C Sbjct: 400 IQKGTPIIISLIGMHRDEEYF-PDPLAYKPERYLENGKDYTQA-----AYLPFGEGPRMC 453 Query: 232 IGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDV--ITLRPKFGLPMIL 86 IG + K IA +L F + + V I L PK G+P+ L Sbjct: 454 IGARMGKVNVKIAIAKVLSNFDLEIRKEKCEIEFGVYGIPLMPKSGVPVRL 504
>CP2R1_MOUSE (Q6VVW9) Cytochrome P450 2R1 (EC 1.14.14.-) (Vitamin D| 25-hydroxylase) Length = 501 Score = 55.1 bits (131), Expect = 9e-08 Identities = 34/113 (30%), Positives = 59/113 (52%), Gaps = 1/113 (0%) Frame = -3 Query: 427 DLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGKHPNALLSFSS 248 D V G +PKGT + + ++H D++ W +D + F P RF + K AL+ FS Sbjct: 386 DAVVRGYSIPKGTTVITNLYSVHFDEKYW-KDPDMFYPERFLDSNGYFTKK-EALIPFSL 443 Query: 247 GPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVI-TLRPKFGLPM 92 G R C+G+ A +E +LQ+F ++H P +++ L+P+ G+ + Sbjct: 444 GRRHCLGEQLARMEMFLFFTSLLQQF-------HLHFPHELVPNLKPRLGMTL 489
>CP310_DROME (Q9VJ71) Probable cytochrome P450 310a1 (EC 1.14.-.-) (CYPCCCXA1)| Length = 492 Score = 55.1 bits (131), Expect = 9e-08 Identities = 40/143 (27%), Positives = 62/143 (43%), Gaps = 13/143 (9%) Frame = -3 Query: 460 PVAAIQRKAGSDLEVGGIK--VPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTR 287 P+ I+R + K + +G + +P+ +HRD++ + E ++KPLRF Sbjct: 347 PLPIIERVCRKSYSLPNSKFTIDEGKTLMVPLLAMHRDEKYFSEPM-KYKPLRFLQTAND 405 Query: 286 AGK-----HPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYV------H 140 G+ N + F G C+GQNFA + K + +LQ F L V H Sbjct: 406 VGQCEDKTKSNVFIGFGIGGSQCVGQNFAKLVIKVALIKLLQNFHLELDANQVKTLKVSH 465 Query: 139 APMDVITLRPKFGLPMILKSPEM 71 P I K GL + LK E+ Sbjct: 466 RPAPFI--HTKDGLKVKLKRREI 486
>CP56_YEAST (P21595) Cytochrome P450-DIT2 (EC 1.14.14.-) (Cytochrome P450 56)| Length = 489 Score = 55.1 bits (131), Expect = 9e-08 Identities = 32/113 (28%), Positives = 57/113 (50%), Gaps = 11/113 (9%) Frame = -3 Query: 409 IKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVT------RAGKHPNALLSFSS 248 I +PKG + D + WG A++FKP R+ + + R K+ A+ F Sbjct: 371 IVIPKGVYVGYNNFGTSHDPKTWGTTADDFKPERWGSDIETIRKNWRMAKNRCAVTGFHG 430 Query: 247 GPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVH-----APMDVITLRPKF 104 G R+C+G+ A+ E + +A +L++F +SL P++ P+ + L+ KF Sbjct: 431 GRRACLGEKLALTEMRISLAEMLKQFRWSLDPEWEEKLTPAGPLCPLNLKLKF 483
>C71A8_MENPI (Q42716) Cytochrome P450 71A8 (EC 1.14.-.-)| Length = 502 Score = 54.7 bits (130), Expect = 1e-07 Identities = 32/97 (32%), Positives = 49/97 (50%) Frame = -3 Query: 448 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGKHPN 269 + R A +D+EV G VP GT++ I I RD W ++ +F+P RF N Sbjct: 377 VPRVARNDVEVMGYDVPVGTMVMINAWAIGRDPTSW-DEPEKFRPERFLNSSVDFKGLDF 435 Query: 268 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSL 158 L+ F +G R C G F M + +A ++Q+F + L Sbjct: 436 ELIPFGAGRRGCPGTTFPMATLEFTLANLMQKFDWEL 472
>CP1A1_CHACA (Q92039) Cytochrome P450 1A1 (EC 1.14.14.1) (CYPIA1)| Length = 521 Score = 54.7 bits (130), Expect = 1e-07 Identities = 35/117 (29%), Positives = 57/117 (48%), Gaps = 2/117 (1%) Frame = -3 Query: 436 AGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFE--NGVTRAGKHPNAL 263 + D + G +PK T + I I+RD E+W +D + F P RF NG + + Sbjct: 395 SAKDTSLNGYFIPKDTCVFINQWQINRDPELW-KDPSSFNPDRFLSCNGTEVNKQEGEKV 453 Query: 262 LSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITLRPKFGLPM 92 + F G R CIG+ A E +A+++QR F P +++ + P++GL M Sbjct: 454 MVFGMGKRRCIGEVIARNEVYRGLAILIQRLQFH------EMPGELLDMTPEYGLTM 504
>C4AE1_DROME (O46054) Cytochrome P450 4ae1 (EC 1.14.-.-) (CYPIVAE1)| Length = 496 Score = 54.7 bits (130), Expect = 1e-07 Identities = 37/126 (29%), Positives = 64/126 (50%) Frame = -3 Query: 460 PVAAIQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAG 281 P+ A+ R DL + +P GT + + + + RD+ ++ D F+P R G Sbjct: 370 PIPAVARCLEKDLVIDEGYIPVGTNVVVLLWQLLRDEAIF-TDPLVFQPER-HLGEEAPR 427 Query: 280 KHPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITLRPKFG 101 P + + FS+GPR+CIGQ FA++E K ++ +++ + V P I LR K G Sbjct: 428 LSPYSYIPFSAGPRNCIGQKFALLEMKTMVTKVIRHYQLLPMGADVE-PSIKIVLRSKSG 486 Query: 100 LPMILK 83 + + L+ Sbjct: 487 VNVGLR 492
>CP6D4_DROME (Q9VCW1) Probable cytochrome P450 6d4 (EC 1.14.-.-) (CYPVID4)| Length = 515 Score = 54.7 bits (130), Expect = 1e-07 Identities = 35/103 (33%), Positives = 47/103 (45%), Gaps = 1/103 (0%) Frame = -3 Query: 403 VPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGKHPNALLSFSSGPRSCIGQ 224 +PKGT + I + IH D E + D + P RF +P A + F GPR CI Q Sbjct: 404 IPKGTPVVISLYGIHHDAEYF-PDPETYDPERFSE--ESRNYNPTAFMPFGEGPRICIAQ 460 Query: 223 NFAMIEAKAVIAMILQRFSFS-LSPKYVHAPMDVITLRPKFGL 98 I +K I ILQ F+ +S + I L PK G+ Sbjct: 461 RMGRINSKLAIIKILQNFNVEVMSRSEIEFENSGIALIPKHGV 503
>CP6A9_DROME (Q27594) Cytochrome P450 6a9 (EC 1.14.-.-) (CYPVIA9)| Length = 504 Score = 54.7 bits (130), Expect = 1e-07 Identities = 31/100 (31%), Positives = 53/100 (53%), Gaps = 3/100 (3%) Frame = -3 Query: 448 IQRKAGSDLEVGG---IKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGK 278 + R+ D EV G + KG + IP +HRD++++ + N F P F + + Sbjct: 377 LNRECLEDYEVPGHPKYVIKKGMPVLIPCGAMHRDEKLYA-NPNTFNPDNFSPERVKE-R 434 Query: 277 HPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSL 158 L F GPR+CIG F ++A++ +A+++ RF FS+ Sbjct: 435 DSVEWLPFGDGPRNCIGMRFGQMQARSGLALLINRFKFSV 474
>CP1A1_MESAU (Q00557) Cytochrome P450 1A1 (EC 1.14.14.1) (CYPIA1) (P-450MC)| Length = 524 Score = 54.3 bits (129), Expect = 2e-07 Identities = 34/116 (29%), Positives = 59/116 (50%), Gaps = 4/116 (3%) Frame = -3 Query: 427 DLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGKHPNALLS--- 257 D + G +PKG + + I+ ++E+WG D N+F+P RF +T +G L Sbjct: 397 DTSLCGFYIPKGHCVFVNQWQINHNQELWG-DPNKFRPERF---LTSSGTLDKVLSGKVT 452 Query: 256 -FSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITLRPKFGLPM 92 F G R CIG+ +E +A++LQ+ F++SP + + + P +GL + Sbjct: 453 LFGLGKRKCIGETIGRLEVFLFLAILLQQIEFTVSPG------EKVDMTPIYGLTL 502
>CP17A_SQUAC (Q92113) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 509 Score = 54.3 bits (129), Expect = 2e-07 Identities = 34/105 (32%), Positives = 54/105 (51%), Gaps = 4/105 (3%) Frame = -3 Query: 448 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGKH-- 275 I A +D +G +PKGT + I + IH D++ W ++ + F P RF + GK+ Sbjct: 374 IPHVALADSSIGDYTIPKGTRVIINLWAIHHDEKEW-KNPDAFDPGRF---LDEDGKYVC 429 Query: 274 --PNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKY 146 + L F +G R C+G+ A +E + ILQRF+ + P Y Sbjct: 430 SSSESYLPFGAGTRVCLGEMLARMELFLFTSWILQRFTVQVPPGY 474
>C4D14_DROME (O46051) Probable cytochrome P450 4d14 (EC 1.14.-.-) (CYPIVD14)| Length = 507 Score = 54.3 bits (129), Expect = 2e-07 Identities = 43/126 (34%), Positives = 64/126 (50%), Gaps = 1/126 (0%) Frame = -3 Query: 457 VAAIQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGK 278 V I R D + G +P + + I I RD + + D +F P RF + R G+ Sbjct: 382 VPIIGRYISQDTVLDGKLIPADSNVIILIYHAQRDPDYF-PDPEKFIPDRFS--MERKGE 438 Query: 277 -HPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITLRPKFG 101 P A FS+GPR+CIGQ FAM+E K+ I+ +++ F + V ++VI LR G Sbjct: 439 ISPFAYTPFSAGPRNCIGQKFAMLEMKSTISKMVRHFELLPLGEEVQPVLNVI-LRSTTG 497 Query: 100 LPMILK 83 + LK Sbjct: 498 INCGLK 503
>CP21A_PIG (P15540) Cytochrome P450 21 (EC 1.14.99.10) (Cytochrome P450 XXI)| (Steroid 21-hydroxylase) (21-OHase) (P450-C21) (P-450c21) Length = 492 Score = 54.3 bits (129), Expect = 2e-07 Identities = 32/95 (33%), Positives = 51/95 (53%) Frame = -3 Query: 451 AIQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGKHP 272 A+ +A + G +P+GTV+ + H D+ VW E +EF+P RF G +P Sbjct: 361 ALPHRATRPSSIFGYDIPEGTVVIPNLQGAHLDETVW-EQPHEFRPDRF----LAPGANP 415 Query: 271 NALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFS 167 +A L+F G R C+G+ A +E V+ +LQ F+ Sbjct: 416 SA-LAFGCGARVCLGEPLARLELFVVLVQLLQAFT 449
>CP192_CARAU (O73686) Cytochrome P450 19 type 2 (EC 1.14.14.1) (Ovarian| aromatase) (CYPXIXA2) (Estrogen synthetase) (P-450AROM) Length = 518 Score = 54.3 bits (129), Expect = 2e-07 Identities = 32/92 (34%), Positives = 49/92 (53%) Frame = -3 Query: 442 RKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGKHPNAL 263 R+A D + G KV +GT I + + +HR + + NEF F+ V P Sbjct: 395 RRALDDDVIEGYKVKRGTNIILNVGRMHRSE--FFPKPNEFSLDNFQKNVPSRFFQP--- 449 Query: 262 LSFSSGPRSCIGQNFAMIEAKAVIAMILQRFS 167 F SGPRSC+G++ AM+ K+++ +L RFS Sbjct: 450 --FGSGPRSCVGKHMAMVMMKSILVTLLSRFS 479
>CP6B7_HELAM (O61387) Cytochrome P450 6B7 (EC 1.14.14.1) (CYPVIB7)| Length = 504 Score = 54.3 bits (129), Expect = 2e-07 Identities = 39/126 (30%), Positives = 62/126 (49%), Gaps = 6/126 (4%) Frame = -3 Query: 457 VAAIQRKAGSDLEVGG--IKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRA 284 V +QRKA D ++ G + + K T++ I IH D + + ++ +F P RF+ Sbjct: 371 VEPLQRKATRDYQIPGTDVVIEKDTMVLISPRGIHYDPKYY-DNPKQFNPDRFD--AEEV 427 Query: 283 GK-HPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLS---PKYVHAPMDVITL 116 GK HP A L F G R+CIG F +++ I IL +F S + + +T+ Sbjct: 428 GKRHPCAYLPFGLGQRNCIGMRFGRLQSLLCITKILSKFRIEPSKNTDRNLQVEPRRVTI 487 Query: 115 RPKFGL 98 PK G+ Sbjct: 488 GPKGGI 493
>C76C2_ARATH (O64637) Cytochrome P450 76C2 (EC 1.14.-.-)| Length = 512 Score = 53.9 bits (128), Expect = 2e-07 Identities = 34/97 (35%), Positives = 48/97 (49%) Frame = -3 Query: 448 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGKHPN 269 + RKA SD+EV G VPK T + + + I RD VW E+++ FKP RF Sbjct: 381 VPRKAESDVEVLGFMVPKDTQVFVNVWAIGRDPNVW-ENSSRFKPERFLGKDIDLRGRDY 439 Query: 268 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSL 158 L F +G R C G A+ ++A +L F + L Sbjct: 440 ELTPFGAGRRICPGLPLAVKTVPLMLASLLYSFDWKL 476
>CP137_MYCTU (O69653) Putative cytochrome P450 137 (EC 1.14.-.-)| Length = 476 Score = 53.9 bits (128), Expect = 2e-07 Identities = 35/102 (34%), Positives = 51/102 (50%), Gaps = 2/102 (1%) Frame = -3 Query: 460 PVAAIQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAG 281 P R A L +GG +V GT I + I I+R EV+ E +EF+P RF G Sbjct: 352 PAPLTARVAAQPLTIGGYRVEAGTRIVVHIIAINRSAEVY-EHPHEFRPERF------LG 404 Query: 280 KHPN--ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFS 161 P A + F G + C+G NF+M E V+ ++L+ F+ Sbjct: 405 TRPQTYAWVPFGGGVKRCLGANFSMRELITVLHVLLREGEFT 446
>C98A2_SOYBN (O48922) Cytochrome P450 98A2 (EC 1.14.-.-)| Length = 509 Score = 53.9 bits (128), Expect = 2e-07 Identities = 32/97 (32%), Positives = 53/97 (54%), Gaps = 1/97 (1%) Frame = -3 Query: 448 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRF-ENGVTRAGKHP 272 + +A ++++VGG +PKG+ + + + + RD VW +D EF+P RF E V G H Sbjct: 369 LPHRANANVKVGGYDIPKGSNVHVNVWAVARDPAVW-KDPLEFRPERFLEEDVDMKG-HD 426 Query: 271 NALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFS 161 LL F SG R C G + A +++ +L F ++ Sbjct: 427 FRLLPFGSGRRVCPGAQLGINLAASMLGHLLHHFCWT 463
>CP2DQ_MOUSE (Q8CIM7) Cytochrome P450 2D26 (EC 1.14.14.1) (CYPIID26)| Length = 500 Score = 53.9 bits (128), Expect = 2e-07 Identities = 31/90 (34%), Positives = 49/90 (54%) Frame = -3 Query: 427 DLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGKHPNALLSFSS 248 D++ +PKGT + ++++ +D+ VW E F P F + KH A + FS+ Sbjct: 384 DIKFQDFFIPKGTTLIPNLSSVLKDETVW-EKPLRFYPEHFLDAQGHFVKH-EAFMPFSA 441 Query: 247 GPRSCIGQNFAMIEAKAVIAMILQRFSFSL 158 G RSC+G+ A +E +LQRFSFS+ Sbjct: 442 GRRSCLGEPLARMELFLFFTCLLQRFSFSV 471
>C97B2_SOYBN (O48921) Cytochrome P450 97B2 (EC 1.14.-.-)| Length = 576 Score = 53.9 bits (128), Expect = 2e-07 Identities = 37/129 (28%), Positives = 56/129 (43%), Gaps = 28/129 (21%) Frame = -3 Query: 460 PVAAIQRKAGSDLEVGGIK-------VPKGTVITIPIATIHRDKEVWGEDANEFKPLRF- 305 P I+R SD+ GG K +P GT + I + +HR W + ++F+P RF Sbjct: 417 PPLLIRRSLKSDVLPGGHKGEKDGYAIPAGTDVFISVYNLHRSPYFW-DRPDDFEPERFL 475 Query: 304 --------------ENGVTRAGKHPN------ALLSFSSGPRSCIGQNFAMIEAKAVIAM 185 + + +PN A L F GPR C+G FA++E+ + M Sbjct: 476 VQNKNEEIEGWAGLDPSRSPGALYPNEVISDFAFLPFGGGPRKCVGDQFALMESTVALTM 535 Query: 184 ILQRFSFSL 158 +LQ F L Sbjct: 536 LLQNFDVEL 544
>C71BD_ARATH (P58050) Cytochrome P450 71B13 (EC 1.14.-.-)| Length = 496 Score = 53.9 bits (128), Expect = 2e-07 Identities = 41/123 (33%), Positives = 61/123 (49%), Gaps = 1/123 (0%) Frame = -3 Query: 442 RKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRF-ENGVTRAGKHPNA 266 R+A D+++GG +PK T I + I IHR+ VW +D F P RF +N + G + Sbjct: 368 REASKDVKIGGYNIPKKTWIHVNIWAIHRNPNVW-KDPEAFIPERFMDNQIDYKGLN-FE 425 Query: 265 LLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITLRPKFGLPMIL 86 LL F SG R C G M + +L RF + L P+ + ++ + L +GL Sbjct: 426 LLPFGSGRRICPGIGMGMALIHLTLINLLYRFDWKL-PEGME--VEDVDLEESYGLVCPK 482 Query: 85 KSP 77 K P Sbjct: 483 KVP 485
>C71BB_ARATH (P58049) Cytochrome P450 71B11 (EC 1.14.-.-)| Length = 496 Score = 53.9 bits (128), Expect = 2e-07 Identities = 41/125 (32%), Positives = 61/125 (48%), Gaps = 1/125 (0%) Frame = -3 Query: 448 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRF-ENGVTRAGKHP 272 I R+A D+++GG +PK T I + I IHR+ VW +D F P RF +N + G + Sbjct: 366 IPREASKDVKIGGYDIPKKTWIHVNIWAIHRNPNVW-KDPEAFIPERFMDNQIDYKGLN- 423 Query: 271 NALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITLRPKFGLPM 92 L F SG R C G M + +L RF + L P+ + ++ + L +GL Sbjct: 424 FEFLPFGSGRRMCPGIGMGMALVHLTLINLLYRFDWKL-PEGME--VEDVDLEESYGLVC 480 Query: 91 ILKSP 77 K P Sbjct: 481 PKKVP 485
>CP305_DROME (Q9VW43) Probable cytochrome P450 305a1 (EC 1.14.-.-) (CYPCCCVA1)| Length = 504 Score = 53.9 bits (128), Expect = 2e-07 Identities = 42/118 (35%), Positives = 57/118 (48%), Gaps = 6/118 (5%) Frame = -3 Query: 442 RKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGK--HPN 269 R+A ++GG +PK I I + ++H DKE W +D EF+P RF + AGK Sbjct: 383 RRALWATKLGGYDIPKNATILISLRSVHLDKEHW-KDPLEFRPERF---IDSAGKCFKDE 438 Query: 268 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSL----SPKYVHAPMDVITLRPK 107 + F G R C+G A + + I+Q FS L SP V P ITL PK Sbjct: 439 YFMPFGMGRRRCLGDALARACIFSFLVRIVQHFSVVLPAGESPSMVLLP--GITLTPK 494
>C71AQ_ARATH (Q9STK7) Cytochrome P450 71A26 (EC 1.14.-.-)| Length = 489 Score = 53.9 bits (128), Expect = 2e-07 Identities = 29/98 (29%), Positives = 48/98 (48%) Frame = -3 Query: 448 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGKHPN 269 + ++ D+ +G +P GT + I I R+ WG D EF+P R + Sbjct: 360 VPHESTQDVRLGDHHIPAGTQVLINAWAIGREAATWGPDVEEFRPERHLDSSVDYRGQAF 419 Query: 268 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLS 155 L+ F SG R C +FA++ + V+A ++ RF + LS Sbjct: 420 ELIPFGSGRRICPAISFAVVLNEVVLANLVHRFDWRLS 457
>CP52V_CANAP (P43083) Cytochrome P450 52E1 (EC 1.14.14.-) (CYPLIIE1)| Length = 519 Score = 53.9 bits (128), Expect = 2e-07 Identities = 30/79 (37%), Positives = 41/79 (51%) Frame = -3 Query: 403 VPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGKHPNALLSFSSGPRSCIGQ 224 VPKG + ++ R ++WG DA F+P R+ N A + F+ GPR C+GQ Sbjct: 406 VPKGQNVFYSTYSMQRRTDIWGPDATTFRPDRW-NEPREALASGWDYIPFNGGPRICLGQ 464 Query: 223 NFAMIEAKAVIAMILQRFS 167 FA+ EA I I Q FS Sbjct: 465 QFALTEASYTIVRICQEFS 483
>CP392_DROME (P82713) Probable cytochrome P450 309a2 (EC 1.14.-.-) (CYPCCCIXA2)| Length = 538 Score = 53.5 bits (127), Expect = 3e-07 Identities = 31/84 (36%), Positives = 40/84 (47%) Frame = -3 Query: 421 EVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGKHPNALLSFSSGP 242 E + V G I IP H DK+ + E FKP RF+NG + L FS GP Sbjct: 422 ESKSLDVEVGMTIMIPNYQFHHDKQYFPEP-EAFKPERFDNGAYQELMRKGIFLPFSDGP 480 Query: 241 RSCIGQNFAMIEAKAVIAMILQRF 170 R C+G AM+ K+ + IL F Sbjct: 481 RICMGVPLAMLTLKSALVHILSNF 504
>C71AR_ARATH (O65438) Cytochrome P450 71A27 (EC 1.14.-.-)| Length = 499 Score = 53.5 bits (127), Expect = 3e-07 Identities = 29/98 (29%), Positives = 53/98 (54%), Gaps = 3/98 (3%) Frame = -3 Query: 442 RKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLR---FENGVTRAGKHP 272 R D+++ G + GT + I + R+ +WG DANE++P R +E G R Sbjct: 369 RLPSEDVQLKGYDISAGTHVIINAWALQRNPAIWGLDANEYRPERHFWYEFGFQRT---D 425 Query: 271 NALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSL 158 + + F +G R C G F+++ +K +A +++RF++ L Sbjct: 426 SKFVPFGAGRRLCPGIGFSLVLSKLALANLVKRFNWRL 463
>C71AO_ARATH (Q9STK9) Cytochrome P450 71A24 (EC 1.14.-.-)| Length = 486 Score = 53.5 bits (127), Expect = 3e-07 Identities = 29/108 (26%), Positives = 52/108 (48%) Frame = -3 Query: 448 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGKHPN 269 + ++ D+++ +P GT + I I R+ WG DA EF+P R N Sbjct: 360 VPHESTHDVKLRDYHIPAGTHVMINAWAIGREAATWGPDAEEFRPERHLNSYVDYRGQDT 419 Query: 268 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDV 125 L+ F +G R C +FA++ + V+A ++ +F ++L + DV Sbjct: 420 ELVPFGAGRRICPAISFAVVLDEVVLANLVHQFDWTLPEESTEYQTDV 467
>CP1A4_CHICK (P79760) Cytochrome P450 1A4 (EC 1.14.14.1) (CYPIA4) (P450 TCDDAHH)| Length = 530 Score = 53.5 bits (127), Expect = 3e-07 Identities = 37/120 (30%), Positives = 56/120 (46%), Gaps = 2/120 (1%) Frame = -3 Query: 427 DLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFEN--GVTRAGKHPNALLSF 254 D + G +PK T + I + D+++W +D FKP RF N G + + +L F Sbjct: 404 DTVLNGYYIPKDTCVFINQWQANHDEKIW-KDPPSFKPERFLNAAGTELSRTEADKVLIF 462 Query: 253 SSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITLRPKFGLPMILKSPE 74 G R CIG++ E + ILQ+ SL AP + + P++GL M K E Sbjct: 463 GLGKRRCIGESIGRWEVFLFLTTILQQLEISL------APGQRVDITPQYGLTMKYKQCE 516
>CP6B6_HELAM (Q95031) Cytochrome P450 6B6 (EC 1.14.14.1) (CYPVIB6)| Length = 504 Score = 53.5 bits (127), Expect = 3e-07 Identities = 34/99 (34%), Positives = 52/99 (52%), Gaps = 3/99 (3%) Frame = -3 Query: 457 VAAIQRKAGSDLEVGG--IKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRA 284 V +QRKA D ++ G + + K T++ I IH D + + ++ +F P RF+ Sbjct: 371 VEPLQRKATRDYKIPGTDVVIEKDTIVLISPRGIHYDPKYY-DNPKQFNPDRFD--AEEV 427 Query: 283 GK-HPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRF 170 GK HP A L F G R+CIG F +++ I IL +F Sbjct: 428 GKRHPCAYLPFGLGQRNCIGMRFGRLQSLLCITKILSKF 466
>C75A7_EUSGR (O04790) Flavonoid 3',5'-hydroxylase (EC 1.14.13.88) (F3'5'H)| (Cytochrome P450 75A7) Length = 510 Score = 53.1 bits (126), Expect = 3e-07 Identities = 33/110 (30%), Positives = 52/110 (47%), Gaps = 3/110 (2%) Frame = -3 Query: 448 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRF---ENGVTRAGK 278 + R A EV G +PKGT +++ I I RD VW E+ NEF P RF +N Sbjct: 374 LPRIASQACEVNGHYIPKGTRLSVNIWAIGRDPSVW-ENPNEFNPDRFLERKNAKIDPRG 432 Query: 277 HPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMD 128 + L+ F +G R C G ++ + ++ ++ F + L + MD Sbjct: 433 NDFELIPFGAGRRICAGTRLGILLVEYILGTLVHSFVWELPSSVIELNMD 482
>C81F1_ARATH (O65790) Cytochrome P450 81F1 (EC 1.14.-.-)| Length = 500 Score = 53.1 bits (126), Expect = 3e-07 Identities = 30/101 (29%), Positives = 51/101 (50%), Gaps = 2/101 (1%) Frame = -3 Query: 460 PVAA--IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTR 287 PVA I R D+++GG VP+ T++ + IHRD E+W E+ +F P R+ +G Sbjct: 363 PVAPFLIPRSPTDDMKIGGYDVPRDTIVMVNAWAIHRDPEIW-EEPEKFNPDRYNDG-CG 420 Query: 286 AGKHPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSF 164 + + L+ F +G R+C G + ++Q F + Sbjct: 421 SDYYVYKLMPFGNGRRTCPGAGLGQRIVTLALGSLIQCFEW 461
>C94A1_VICSA (O81117) Cytochrome P450 94A1 (EC 1.14.-.-) (P450-dependent fatty| acid omega-hydroxylase) Length = 514 Score = 53.1 bits (126), Expect = 3e-07 Identities = 33/104 (31%), Positives = 55/104 (52%), Gaps = 7/104 (6%) Frame = -3 Query: 460 PVAAIQRKA-GSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRF-----EN 299 PV ++A D+ G V KGT++T + + R K +WG+D EF+P R+ N Sbjct: 376 PVPMDSKEAVNDDVLPDGWVVKKGTIVTYHVYAMGRMKSLWGDDWAEFRPERWLEKDEVN 435 Query: 298 GV-TRAGKHPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRF 170 G G+ + F +GPR C+G+ A ++ K ++A I+ +F Sbjct: 436 GKWVFVGRDSYSYPVFQAGPRVCLGKEMAFMQMKRIVAGIVGKF 479
>C71AJ_ARATH (Q9T0K0) Cytochrome P450 71A19 (EC 1.14.-.-)| Length = 490 Score = 53.1 bits (126), Expect = 3e-07 Identities = 29/97 (29%), Positives = 44/97 (45%) Frame = -3 Query: 448 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGKHPN 269 + R D+ + G +P GT + I I RD WG DA EF+P R + + Sbjct: 362 VPRVFSEDVTLKGYNIPAGTQVIINAWAIQRDTTTWGIDAEEFRPERHLDSILDFQGQDF 421 Query: 268 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSL 158 + F SG R C G F +A I++RF++ + Sbjct: 422 KFIPFGSGKRICPGIGFTSALIGVTLANIVKRFNWRM 458
>CP17A_FELCA (Q9GMC8) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 508 Score = 53.1 bits (126), Expect = 3e-07 Identities = 35/104 (33%), Positives = 54/104 (51%), Gaps = 3/104 (2%) Frame = -3 Query: 460 PVAA--IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTR 287 PVA I KA D +G V KGT + I + +H +++ W ++F P RF + Sbjct: 365 PVAPTLIPHKAIMDSSIGEFAVDKGTNVIINLWALHHNEKEWYRP-DQFMPERFLDPTRS 423 Query: 286 AGKHPN-ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSL 158 P+ + L F +GPRSC+G++ A E +A +LQRF + Sbjct: 424 QLISPSLSYLPFGAGPRSCLGESLARQEVFLFMAWLLQRFDLEV 467
>CP391_DROME (Q9VQD2) Probable cytochrome P450 309a1 (EC 1.14.-.-) (CYPCCCIXA1)| Length = 529 Score = 53.1 bits (126), Expect = 3e-07 Identities = 25/75 (33%), Positives = 35/75 (46%) Frame = -3 Query: 394 GTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGKHPNALLSFSSGPRSCIGQNFA 215 G + +P H D +++ E A+EF+P RFENG L F GPR C+G Sbjct: 423 GVTVMVPAYQYHHDNDIYPE-ASEFRPDRFENGAASVLTKRGCFLPFGDGPRICLGMRVG 481 Query: 214 MIEAKAVIAMILQRF 170 + K I IL + Sbjct: 482 QLSVKTAIVHILSNY 496
>CP17A_ORYLA (P70085) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 517 Score = 53.1 bits (126), Expect = 3e-07 Identities = 40/124 (32%), Positives = 64/124 (51%), Gaps = 3/124 (2%) Frame = -3 Query: 460 PVAA--IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTR 287 PVA I A SD +G V KGT + I + ++H D++ W + + F P RF + Sbjct: 374 PVAPLLIPHVALSDTSLGDFTVRKGTRVVINLWSLHHDEKEW-TNPDLFNPGRFLSADGS 432 Query: 286 AGKHPNA-LLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVITLRP 110 + P++ L F +G R C+G+ A +E ++ ILQRF+ S+ P + +L Sbjct: 433 SLTLPSSSYLPFGAGLRVCLGEALAKMELFLFLSWILQRFTLSVPPS-----QSLPSLEG 487 Query: 109 KFGL 98 KFG+ Sbjct: 488 KFGV 491
>CP19A_ANGJA (Q6QHT9) Cytochrome P450 19A1 (EC 1.14.14.1) (Aromatase) (CYPXIX)| (Estrogen synthetase) (P-450AROM) Length = 511 Score = 52.8 bits (125), Expect = 4e-07 Identities = 32/92 (34%), Positives = 50/92 (54%) Frame = -3 Query: 442 RKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGKHPNAL 263 RK+ D + G KV KGT I + + +H+ + + NEF FE V P Sbjct: 388 RKSLEDDVIEGYKVFKGTNIILNVGRMHKCE--FFSKPNEFSLENFEKTVPNRFFQP--- 442 Query: 262 LSFSSGPRSCIGQNFAMIEAKAVIAMILQRFS 167 F SGPRSC+G++ +M+ KA++A +L R++ Sbjct: 443 --FGSGPRSCVGKHISMVMMKAILATLLSRYT 472
>CP17A_MESAU (P70687) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 511 Score = 52.8 bits (125), Expect = 4e-07 Identities = 36/107 (33%), Positives = 55/107 (51%), Gaps = 6/107 (5%) Frame = -3 Query: 460 PVAA--IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTR 287 PVA I +A SD+ +G +PK T + I + +H ++ W + + F P RF + Sbjct: 365 PVAPMLIPHRANSDMSIGEFSIPKFTPVIINLWALHHSEKEW-DQPDRFMPERF---LDP 420 Query: 286 AGKH---PN-ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSL 158 G H P+ + L F +G RSCIG+ A E +A +LQRF + Sbjct: 421 TGSHLITPSLSYLPFGAGARSCIGEVLARQELFLFMAHLLQRFDLDV 467
>C75A5_EUSGR (Q96418) Flavonoid 3',5'-hydroxylase (EC 1.14.13.88) (F3'5'H)| (Cytochrome P450 75A5) Length = 510 Score = 52.8 bits (125), Expect = 4e-07 Identities = 32/110 (29%), Positives = 52/110 (47%), Gaps = 3/110 (2%) Frame = -3 Query: 448 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRF---ENGVTRAGK 278 + R A EV G +PKGT +++ I I RD +W E+ NEF P RF +N Sbjct: 374 LPRIASQACEVNGHYIPKGTRLSVNIWAIGRDPSLW-ENPNEFNPDRFLERKNAKIDPRG 432 Query: 277 HPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMD 128 + L+ F +G R C G ++ + ++ ++ F + L + MD Sbjct: 433 NDFELIPFGAGRRICAGTRLGILLVEYILGTLVHSFDWELPSSVIELNMD 482
>CP2J2_HUMAN (P51589) Cytochrome P450 2J2 (EC 1.14.14.1) (CYPIIJ2) (Arachidonic| acid epoxygenase) Length = 502 Score = 52.8 bits (125), Expect = 4e-07 Identities = 31/96 (32%), Positives = 47/96 (48%), Gaps = 1/96 (1%) Frame = -3 Query: 448 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRF-ENGVTRAGKHP 272 + R+ D + G +PKGT+I + +HRD W + F P F ENG K Sbjct: 380 VPREVTVDTTLAGYHLPKGTMILTNLTALHRDPTEWATP-DTFNPDHFLENGQF---KKR 435 Query: 271 NALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSF 164 A + FS G R+C+G+ A E ++Q+F+F Sbjct: 436 EAFMPFSIGKRACLGEQLARTELFIFFTSLMQKFTF 471
>CP17A_PERLE (Q91Z85) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 509 Score = 52.8 bits (125), Expect = 4e-07 Identities = 40/124 (32%), Positives = 60/124 (48%), Gaps = 6/124 (4%) Frame = -3 Query: 460 PVAA--IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTR 287 PVA I KA D +G +PK T + I + +H +++ W + + F P RF + Sbjct: 363 PVAPMLIPHKANIDSSIGEFTIPKDTHVVINLWALHHNEKEW-DQPDRFMPERF---LDA 418 Query: 286 AGKH---PN-ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMDVIT 119 G H P+ + L F +GPR+CIG+ A +A +LQRF + APM + Sbjct: 419 TGSHLITPSLSYLPFGAGPRACIGEVLARQVLFLYVACLLQRFDLDVPD---GAPMPCLK 475 Query: 118 LRPK 107 PK Sbjct: 476 GDPK 479
>CP6D1_MUSDO (Q27698) Cytochrome P450 6d1 (EC 1.14.-.-) (CYPVID1) (Pyrethroid| resistance cytochrome P450) (Cytochrome P450 Ipr) Length = 516 Score = 52.8 bits (125), Expect = 4e-07 Identities = 32/102 (31%), Positives = 50/102 (49%), Gaps = 2/102 (1%) Frame = -3 Query: 448 IQRKAGSDLEVGGIK--VPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGKH 275 + RK D +V K +PK T I I + IHRD + + + +++P RF + Sbjct: 391 LNRKCTQDFQVPDTKLTIPKETGIIISLLGIHRDPQYFPQP-EDYRPERFAD--ESKDYD 447 Query: 274 PNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPK 149 P A + F GPR CI Q ++ +K +A IL F+ P+ Sbjct: 448 PAAYMPFGEGPRHCIAQRMGVMNSKVALAKILANFNIQPMPR 489
>CP17A_CHICK (P12394) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 508 Score = 52.8 bits (125), Expect = 4e-07 Identities = 35/117 (29%), Positives = 60/117 (51%), Gaps = 6/117 (5%) Frame = -3 Query: 430 SDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGKHPNA----L 263 +D +G +PKG + I + ++H D++ W + EF P RF + G+H ++ Sbjct: 380 ADTSIGEYSIPKGARVVINLWSVHHDEKEW-DKPEEFNPGRF---LDEQGQHIHSPSPSY 435 Query: 262 LSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPKYVHAPMD--VITLRPKFGL 98 L F +G R C+G+ A +E +A +LQRF+ + P D + +L KFG+ Sbjct: 436 LPFGAGIRVCLGEVLAKMELFLFLAWVLQRFT-------LECPQDQPLPSLEGKFGV 485
>CP2J5_MOUSE (O54749) Cytochrome P450 2J5 (EC 1.14.14.1) (CYPIIJ5) (Arachidonic| acid epoxygenase) Length = 501 Score = 52.8 bits (125), Expect = 4e-07 Identities = 31/94 (32%), Positives = 47/94 (50%), Gaps = 1/94 (1%) Frame = -3 Query: 442 RKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRF-ENGVTRAGKHPNA 266 R+ D + G +PKGT+I + +HRD + W F P F ENG K + Sbjct: 381 REVTVDTKFNGFHLPKGTMILTNLTALHRDPKEWATP-EVFNPEHFLENGQF---KKRES 436 Query: 265 LLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSF 164 L FS G R+C+G+ A E + ++Q+F+F Sbjct: 437 FLPFSMGKRACLGEQLAKSELFIFFSALMQKFTF 470
>C6A21_DROME (Q9V774) Probable cytochrome P450 6a21 (EC 1.14.-.-) (CYPVIA21)| Length = 504 Score = 52.8 bits (125), Expect = 4e-07 Identities = 31/103 (30%), Positives = 53/103 (51%), Gaps = 3/103 (2%) Frame = -3 Query: 448 IQRKAGSDLEVGG---IKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGK 278 + R+ D EV G + KG + IP +HRD++++ + N F P F + + Sbjct: 377 LNRECLEDYEVPGHPKYVIKKGMPVLIPCGAMHRDEKLYA-NPNTFNPDNFSPERVKE-R 434 Query: 277 HPNALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSLSPK 149 L F GPR+CIG F ++A+ +A++++ F FS+ K Sbjct: 435 DSVEWLPFGDGPRNCIGMRFGQMQARIGLALLIKDFKFSVCEK 477
>C71AK_ARATH (Q9T0K2) Cytochrome P450 71A20 (EC 1.14.-.-)| Length = 495 Score = 52.8 bits (125), Expect = 4e-07 Identities = 29/97 (29%), Positives = 44/97 (45%) Frame = -3 Query: 448 IQRKAGSDLEVGGIKVPKGTVITIPIATIHRDKEVWGEDANEFKPLRFENGVTRAGKHPN 269 + R D+++ G +P GT + + I RD WG DA EFKP R + Sbjct: 367 VPRVLSEDVKLKGYNIPAGTQVIVNAWAIQRDTTTWGTDAEEFKPERHLDTNLDFQGQDF 426 Query: 268 ALLSFSSGPRSCIGQNFAMIEAKAVIAMILQRFSFSL 158 + F SG R C G F +A I++RF++ + Sbjct: 427 KFIPFGSGKRICPGIGFTSALIGVTLANIVKRFNWRM 463 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 75,132,009 Number of Sequences: 219361 Number of extensions: 1649317 Number of successful extensions: 5293 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 4808 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 4975 length of database: 80,573,946 effective HSP length: 102 effective length of database: 58,199,124 effective search space used: 3026354448 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
