>SIN3A_MOUSE (Q60520) Paired amphipathic helix protein Sin3a (Transcriptional|
corepressor Sin3a) (Histone deacetylase complex subunit
Sin3a)
Length = 1282
Score = 57.0 bits (136), Expect = 2e-08
Identities = 31/75 (41%), Positives = 47/75 (62%), Gaps = 1/75 (1%)
Frame = +3
Query: 162 DALKSAYTQEFHFCEKVKEKLEY-DAYQEFLKCLHIYSQEIITRSELKNLVSDILQHYPD 338
DA K E F +KV++ L +AY+ FL+CL I++QE+I+R+EL LVS L +P+
Sbjct: 455 DASKHGVGTESLFFDKVRKALRSAEAYENFLRCLVIFNQEVISRAELVQLVSPFLGKFPE 514
Query: 339 LMVGFNEFLEHCENI 383
L F FL + E++
Sbjct: 515 LFNWFKNFLGYKESV 529
Score = 30.0 bits (66), Expect = 2.4
Identities = 13/43 (30%), Positives = 25/43 (58%)
Frame = +3
Query: 237 YQEFLKCLHIYSQEIITRSELKNLVSDILQHYPDLMVGFNEFL 365
+ +FL + + + I + + VS + + +PDL++GFN FL
Sbjct: 144 HNDFLDIMKEFKSQSIDTPGVISRVSQLFKGHPDLIMGFNTFL 186
Score = 29.6 bits (65), Expect = 3.1
Identities = 18/77 (23%), Positives = 35/77 (45%), Gaps = 15/77 (19%)
Frame = +3
Query: 180 YTQEFHFCEKVKEKLEY--DAYQEFLKCLHIYSQE-------------IITRSELKNLVS 314
+ ++ K+K + + D Y+ FL+ LH Y +E +T E+ V+
Sbjct: 304 FNHAINYVNKIKNRFQGQPDIYKAFLEILHTYQKEQRNAKEAGGNYTPALTEQEVYAQVA 363
Query: 315 DILQHYPDLMVGFNEFL 365
+ ++ DL+ F +FL
Sbjct: 364 RLFKNQEDLLSEFGQFL 380
>SIN3A_HUMAN (Q96ST3) Paired amphipathic helix protein Sin3a (Transcriptional|
corepressor Sin3a) (Histone deacetylase complex subunit
Sin3a)
Length = 1273
Score = 56.2 bits (134), Expect = 3e-08
Identities = 31/75 (41%), Positives = 47/75 (62%), Gaps = 1/75 (1%)
Frame = +3
Query: 162 DALKSAYTQEFHFCEKVKEKLEY-DAYQEFLKCLHIYSQEIITRSELKNLVSDILQHYPD 338
DA K E F +KV++ L +AY+ FL+CL I++QE+I+R+EL LVS L +P+
Sbjct: 454 DASKHGGGTESLFFDKVRKALRSAEAYENFLRCLVIFNQEVISRAELVQLVSPFLGKFPE 513
Query: 339 LMVGFNEFLEHCENI 383
L F FL + E++
Sbjct: 514 LFNWFKNFLGYKESV 528
Score = 32.0 bits (71), Expect = 0.62
Identities = 14/43 (32%), Positives = 25/43 (58%)
Frame = +3
Query: 237 YQEFLKCLHIYSQEIITRSELKNLVSDILQHYPDLMVGFNEFL 365
Y +FL + + + I + + VS + + +PDL++GFN FL
Sbjct: 144 YNDFLDIMKEFKSQSIDTPGVISRVSQLFKGHPDLIMGFNTFL 186
Score = 29.6 bits (65), Expect = 3.1
Identities = 18/77 (23%), Positives = 35/77 (45%), Gaps = 15/77 (19%)
Frame = +3
Query: 180 YTQEFHFCEKVKEKLEY--DAYQEFLKCLHIYSQE-------------IITRSELKNLVS 314
+ ++ K+K + + D Y+ FL+ LH Y +E +T E+ V+
Sbjct: 304 FNHAINYVNKIKNRFQGQPDIYKAFLEILHTYQKEQRNAKEAGGNYTPALTEQEVYAQVA 363
Query: 315 DILQHYPDLMVGFNEFL 365
+ ++ DL+ F +FL
Sbjct: 364 RLFKNQEDLLSEFGQFL 380
>SIN3B_HUMAN (O75182) Paired amphipathic helix protein Sin3b (Transcriptional|
corepressor Sin3b) (Histone deacetylase complex subunit
Sin3b)
Length = 1162
Score = 53.5 bits (127), Expect = 2e-07
Identities = 25/61 (40%), Positives = 40/61 (65%), Gaps = 1/61 (1%)
Frame = +3
Query: 186 QEFHFCEKVKEKLE-YDAYQEFLKCLHIYSQEIITRSELKNLVSDILQHYPDLMVGFNEF 362
QEF F +KV+ L+ + Y+ FL+C+ +++QE+++ SEL LVS L +P+L F F
Sbjct: 306 QEFSFFDKVRRVLKSQEVYENFLRCIALFNQELVSGSELLQLVSPFLGKFPELFAQFKSF 365
Query: 363 L 365
L
Sbjct: 366 L 366
Score = 33.5 bits (75), Expect = 0.21
Identities = 20/65 (30%), Positives = 32/65 (49%), Gaps = 2/65 (3%)
Frame = +3
Query: 198 FCEKVKEKLEYD--AYQEFLKCLHIYSQEIITRSELKNLVSDILQHYPDLMVGFNEFLEH 371
+ ++VK + D Y FL+ + + + I + VS + +PDL+VGFN FL
Sbjct: 47 YLDQVKIRFGSDPATYNGFLEIMKEFKSQSIDTPGVIRRVSQLFHEHPDLIVGFNAFLPL 106
Query: 372 CENID 386
ID
Sbjct: 107 GYRID 111
>SIN3B_MOUSE (Q62141) Paired amphipathic helix protein Sin3b (Transcriptional|
corepressor Sin3b) (Histone deacetylase complex subunit
Sin3b)
Length = 1098
Score = 53.5 bits (127), Expect = 2e-07
Identities = 25/61 (40%), Positives = 40/61 (65%), Gaps = 1/61 (1%)
Frame = +3
Query: 186 QEFHFCEKVKEKLE-YDAYQEFLKCLHIYSQEIITRSELKNLVSDILQHYPDLMVGFNEF 362
QEF F +KV+ L+ + Y+ FL+C+ +++QE+++ SEL LVS L +P+L F F
Sbjct: 297 QEFSFFDKVRRVLKSQEVYENFLRCIALFNQELVSGSELLQLVSPFLGKFPELFAQFKSF 356
Query: 363 L 365
L
Sbjct: 357 L 357
Score = 33.5 bits (75), Expect = 0.21
Identities = 20/65 (30%), Positives = 32/65 (49%), Gaps = 2/65 (3%)
Frame = +3
Query: 198 FCEKVKEKLEYD--AYQEFLKCLHIYSQEIITRSELKNLVSDILQHYPDLMVGFNEFLEH 371
+ ++VK + D Y FL+ + + + I + VS + +PDL+VGFN FL
Sbjct: 40 YLDQVKIRFGSDPATYNGFLEIMKEFKSQSIDTPGVIRRVSQLFHEHPDLIVGFNAFLPL 99
Query: 372 CENID 386
ID
Sbjct: 100 GYRID 104
>SIN3_YEAST (P22579) Paired amphipathic helix protein SIN3|
Length = 1536
Score = 37.4 bits (85), Expect = 0.015
Identities = 21/73 (28%), Positives = 38/73 (52%), Gaps = 2/73 (2%)
Frame = +3
Query: 153 DNKDALKSAYTQEFHFCEKVKEKL--EYDAYQEFLKCLHIYSQEIITRSELKNLVSDILQ 326
D K + ++Q + K+K + + D Y+ FL+ L Y +E +E+ V+ + Q
Sbjct: 399 DAKKNVDVEFSQAISYVNKIKTRFADQPDIYKHFLEILQTYQREQKPINEVYAQVTHLFQ 458
Query: 327 HYPDLMVGFNEFL 365
+ PDL+ F +FL
Sbjct: 459 NAPDLLEDFKKFL 471
Score = 35.0 bits (79), Expect = 0.074
Identities = 22/65 (33%), Positives = 32/65 (49%), Gaps = 1/65 (1%)
Frame = +3
Query: 186 QEFHFCEKVKEKL-EYDAYQEFLKCLHIYSQEIITRSELKNLVSDILQHYPDLMVGFNEF 362
+E F EK K + Y EFLK L++YSQ+I+ +L V L +L F F
Sbjct: 664 EEVTFFEKAKRYIGNKHLYTEFLKILNLYSQDILDLDDLVEKVDFYLGSNKELFTWFKNF 723
Query: 363 LEHCE 377
+ + E
Sbjct: 724 VGYQE 728
Score = 33.5 bits (75), Expect = 0.21
Identities = 34/121 (28%), Positives = 49/121 (40%), Gaps = 4/121 (3%)
Frame = +3
Query: 15 QDSKELDVG-QHKRKPFPSANLAAGAEAH---QGGHPEIHGIXXXXXXXHDNKDALKSAY 182
QD KE+ G Q P PS+N A + + + H E + KDAL
Sbjct: 175 QDCKEVPAGVQPADAPDPSSNHADANDDNNNNENSHDE-----DADYRPLNVKDALSYLE 229
Query: 183 TQEFHFCEKVKEKLEYDAYQEFLKCLHIYSQEIITRSELKNLVSDILQHYPDLMVGFNEF 362
+F F + D Y FL + + + I + VS + + YP L+ GFN F
Sbjct: 230 QVKFQFSSRP------DIYNLFLDIMKDFKSQAIDTPGVIERVSTLFRGYPILIQGFNTF 283
Query: 363 L 365
L
Sbjct: 284 L 284
>PST1_SCHPO (Q09750) Paired amphipathic helix protein pst1 (SIN3 homolog 1)|
Length = 1522
Score = 36.2 bits (82), Expect = 0.033
Identities = 23/72 (31%), Positives = 36/72 (50%), Gaps = 6/72 (8%)
Frame = +3
Query: 207 KVKEKLEYDAYQEFLKCLHIYSQEIITRSELKNLVSDILQHYPDLMVGFNEFLEHCENID 386
K++ E + Y EFL + + + I E+ VS + YP+L+ GFN FL +I+
Sbjct: 193 KLQFHQEPEIYNEFLDIMKEFKSQAIETPEVITRVSKLFAGYPNLIQGFNTFLPPGYSIE 252
Query: 387 ------GFLAGV 404
G LAG+
Sbjct: 253 ISSADPGSLAGI 264
Score = 30.4 bits (67), Expect = 1.8
Identities = 14/38 (36%), Positives = 23/38 (60%), Gaps = 1/38 (2%)
Frame = +3
Query: 189 EFHFCEKVKEKLEYDA-YQEFLKCLHIYSQEIITRSEL 299
E F E ++ L ++ Y EF+K L +YSQE+ ++ L
Sbjct: 514 ELEFLEHARQYLANESKYNEFIKLLELYSQEVFDKNAL 551
>PST2_SCHPO (O13919) Paired amphipathic helix protein pst2 (SIN3 homolog 2)|
Length = 1075
Score = 30.0 bits (66), Expect = 2.4
Identities = 18/50 (36%), Positives = 25/50 (50%), Gaps = 1/50 (2%)
Frame = +3
Query: 153 DNKDALKSAYTQEFHFCEKVKEKL-EYDAYQEFLKCLHIYSQEIITRSEL 299
DN + F + VK L + + Y EFLK L++Y Q II R+ L
Sbjct: 245 DNLSPFSHLSNESSDFFKNVKNVLTDVETYHEFLKLLNLYVQGIIDRNIL 294
Score = 30.0 bits (66), Expect = 2.4
Identities = 20/61 (32%), Positives = 31/61 (50%), Gaps = 5/61 (8%)
Frame = +3
Query: 198 FCEKVKEKL-----EYDAYQEFLKCLHIYSQEIITRSELKNLVSDILQHYPDLMVGFNEF 362
F +K+ ++L Y A+ + +K LH EI+ +S IL+ YPDL+ N F
Sbjct: 42 FVQKLGQRLCHRPYVYSAFMDVVKALH---NEIVDFPGFIERISVILRDYPDLLEYLNIF 98
Query: 363 L 365
L
Sbjct: 99 L 99
>RDRP_SHMV (P89202) RNA-directed RNA polymerase (EC 2.7.7.48) (186 kDa|
protein) [Contains: Methyltransferase/RNA helicase
(MT/HEL) (128 kDa protein)]
Length = 1629
Score = 28.5 bits (62), Expect = 6.9
Identities = 11/38 (28%), Positives = 21/38 (55%)
Frame = +3
Query: 270 SQEIITRSELKNLVSDILQHYPDLMVGFNEFLEHCENI 383
S+ ++ +E VSD++ P L F +F ++CE +
Sbjct: 557 SEHLVATNEYYAKVSDLVDRNPTLAFDFEKFQDYCEKL 594
Database: uniprot_sprot.fasta
Posted date: May 25, 2006 5:36 PM
Number of letters in database: 80,573,946
Number of sequences in database: 219,361
Lambda K H
0.318 0.135 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 59,351,275
Number of Sequences: 219361
Number of extensions: 1167910
Number of successful extensions: 3027
Number of sequences better than 10.0: 19
Number of HSP's better than 10.0 without gapping: 2944
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3026
length of database: 80,573,946
effective HSP length: 101
effective length of database: 58,418,485
effective search space used: 2336739400
frameshift window, decay const: 50, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)