>ULK1_HUMAN (O75385) Serine/threonine-protein kinase ULK1 (EC 2.7.11.1)|
           (Unc-51-like kinase 1)
          Length = 1050

 Score = 33.1 bits (74), Expect = 0.33
 Identities = 16/40 (40%), Positives = 21/40 (52%)
 Frame = +3

Query: 6   PLLLPPVPSRGSNPCAGRRPAARLPDSCKGRPFLLPPLIG 125
           P   PP PS G   C   R + +LPD  +  P  LPP++G
Sbjct: 585 PQASPPQPSHGLQSCRNLRGSPKLPDFLQRNP--LPPILG 622

>YLPM1_HUMAN (P49750) YLP motif-containing protein 1 (Nuclear protein ZAP3)|
            (ZAP113)
          Length = 1951

 Score = 33.1 bits (74), Expect = 0.33
 Identities = 20/55 (36%), Positives = 24/55 (43%)
 Frame = -3

Query: 169  ERNPPSFLSSHQRAPPISGGRRKGRPLQESGSRAAGRRPAHGFDPREGTGGRRRG 5
            ER PP    S +R P    G R+  P + +GSR  G        P  G G R RG
Sbjct: 915  ERGPPRRAGSQERGPLRRAGSRERIPPRRAGSRERG--------PPRGPGSRERG 961

>KTNA1_STRPU (O61577) Katanin p60 ATPase-containing subunit (EC 3.6.4.3)|
           (Katanin p60 subunit) (p60 katanin)
          Length = 516

 Score = 28.9 bits (63), Expect(2) = 0.51
 Identities = 17/55 (30%), Positives = 23/55 (41%), Gaps = 3/55 (5%)
 Frame = -3

Query: 160 PPSFLSSHQRAPPISGGRRKGRPLQESGSRAAGRRPAH---GFDPREGTGGRRRG 5
           PP     H+ +PP     RK  P +   S+ A R P +   G  P +  G  R G
Sbjct: 116 PPPTPVDHRPSPPYQRAARKDPPRRSEPSKPANRAPGNDRGGRGPSDRRGDARSG 170



 Score = 22.3 bits (46), Expect(2) = 0.51
 Identities = 18/91 (19%), Positives = 36/91 (39%), Gaps = 18/91 (19%)
 Frame = -2

Query: 419 CQRGRGGRQE---DSYQRSVEPHGGILEDLP--------PNEGREEDVEGERQRQEHGHG 273
           C+  + GR+     +Y+ S+  + G+L+ +         P    +     +   QE+ H 
Sbjct: 7   CENTKMGREYALLGNYETSLVYYQGVLQQIQKLLTSVHEPQRKHQWQTIRQELSQEYEHV 66

Query: 272 DHLERVVRELP-------PMPPHRLAPDNQH 201
            ++ + +           P P HR AP + H
Sbjct: 67  KNITKTLNGFKSEPAAPEPAPNHRAAPFSHH 97

>ACRBP_MOUSE (Q3V140) Acrosin-binding protein precursor (Proacrosin-binding|
           protein sp32)
          Length = 540

 Score = 31.2 bits (69), Expect = 1.3
 Identities = 23/68 (33%), Positives = 31/68 (45%), Gaps = 2/68 (2%)
 Frame = -2

Query: 446 ASQTTGRSPCQRGRGGRQEDSYQRSVEPHGGILEDLPPNEGREEDVEGERQRQEHGHGDH 267
           +S + G    Q  R   QE   Q  ++ H   LE+    E +EE+ E E  +QE G G  
Sbjct: 181 SSLSLGGKDQQSSRRPGQEQRKQEQIQEHK--LEEAQEQEEQEEEEEEEEAKQEEGQGTE 238

Query: 266 --LERVVR 249
             LE V R
Sbjct: 239 AGLESVSR 246

>SNUT1_HUMAN (O43290) U4/U6.U5 tri-snRNP-associated protein 1 (U4/U6.U5|
           tri-snRNP-associated 110 kDa protein) (Squamous cell
           carcinoma antigen recognized by T cells 1) (SART-1)
           (hSART-1) (hSnu66)
          Length = 800

 Score = 30.8 bits (68), Expect = 1.7
 Identities = 16/37 (43%), Positives = 20/37 (54%)
 Frame = -3

Query: 118 SGGRRKGRPLQESGSRAAGRRPAHGFDPREGTGGRRR 8
           SGG R+ R  +  G R +GRR A   + R  T GR R
Sbjct: 48  SGGERRKRSRERGGERGSGRRGAEA-EARSSTHGRER 83

>H2B3_PARAN (P02292) Histone H2B.3, sperm|
          Length = 148

 Score = 30.4 bits (67), Expect = 2.2
 Identities = 18/45 (40%), Positives = 21/45 (46%)
 Frame = -3

Query: 142 SHQRAPPISGGRRKGRPLQESGSRAAGRRPAHGFDPREGTGGRRR 8
           S  +  P  G  RKG P + S SR A  +       R G GGRRR
Sbjct: 3   SPAKTSPRKGSPRKGSPRKGSPSRKASPKRGGKGAKRAGKGGRRR 47

>IF2_SYNY3 (P72689) Translation initiation factor IF-2|
          Length = 1001

 Score = 24.3 bits (51), Expect(2) = 2.8
 Identities = 11/28 (39%), Positives = 15/28 (53%)
 Frame = +2

Query: 182 LPSSRSRAGCQGRGDEAAWVAAPLPPSP 265
           L  +R +A   G  +E   +AAP PP P
Sbjct: 213 LKDNRGQARSPGDREEKVAIAAPEPPKP 240



 Score = 24.3 bits (51), Expect(2) = 2.8
 Identities = 14/33 (42%), Positives = 17/33 (51%)
 Frame = +3

Query: 3   KPLLLPPVPSRGSNPCAGRRPAARLPDSCKGRP 101
           +PL  PPVPS  S P    +PA   P + K  P
Sbjct: 149 QPLAPPPVPSLQSPP---SKPAPPTPPAKKAAP 178

>CS007_MOUSE (Q6ZPZ3) Zinc finger CCCH-type domain-containing protein C19orf7|
           homolog
          Length = 1304

 Score = 29.6 bits (65), Expect = 3.7
 Identities = 22/79 (27%), Positives = 31/79 (39%), Gaps = 11/79 (13%)
 Frame = -2

Query: 410 GRGGRQEDSYQRSVEPHGGILEDLPP-----------NEGREEDVEGERQRQEHGHGDHL 264
           G GG     Y     PH G++  +PP            EG E +       +++GH + L
Sbjct: 675 GPGGPPMMPYGPGDSPHSGMMPPIPPAQNFYENFYPQQEGMEMEPGLVGDAEDYGHYEEL 734

Query: 263 ERVVRELPPMPPHRLAPDN 207
                E P  P H L PD+
Sbjct: 735 PGQPGE-PLFPEHPLEPDS 752

>EBNA6_EBV (P03204) Epstein-Barr nuclear antigen 6 (EBV nuclear antigen 6)|
           (EBNA-6) (EBNA-3C) (EBNA-4B)
          Length = 992

 Score = 29.6 bits (65), Expect = 3.7
 Identities = 23/78 (29%), Positives = 32/78 (41%), Gaps = 2/78 (2%)
 Frame = -2

Query: 440 QTTGRSPCQRGRGGR--QEDSYQRSVEPHGGILEDLPPNEGREEDVEGERQRQEHGHGDH 267
           Q  G  P   G   R   E+SY R  +P G    D   N G  + +   R+R+    G  
Sbjct: 30  QDPGPGPPSSGASERLVPEESYSRDQQPWGQSRGD--ENRGWMQRIRRRRRRRAALSGHL 87

Query: 266 LERVVRELPPMPPHRLAP 213
           L+      P +PPH + P
Sbjct: 88  LDTEDNVPPWLPPHDITP 105

>CENPB_HUMAN (P07199) Major centromere autoantigen B (Centromere protein B)|
           (CENP-B)
          Length = 599

 Score = 29.6 bits (65), Expect = 3.7
 Identities = 15/50 (30%), Positives = 23/50 (46%)
 Frame = -2

Query: 413 RGRGGRQEDSYQRSVEPHGGILEDLPPNEGREEDVEGERQRQEHGHGDHL 264
           +  G  +E+  +   E  G         EG EE+ EGE + +E G G+ L
Sbjct: 402 KSEGEEEEEEEEEEEEEEG---------EGEEEEEEGEEEEEEGGEGEEL 442

>HCN3_RAT (Q9JKA8) Potassium/sodium hyperpolarization-activated cyclic|
           nucleotide-gated channel 3
          Length = 780

 Score = 29.3 bits (64), Expect = 4.8
 Identities = 17/42 (40%), Positives = 20/42 (47%), Gaps = 3/42 (7%)
 Frame = -3

Query: 127 PPISGGRR---KGRPLQESGSRAAGRRPAHGFDPREGTGGRR 11
           PP  GGRR   +GRPL  S      R    G   R+G+G  R
Sbjct: 703 PPGGGGRRLGPRGRPLSASQPSLPQRATGDGSPRRKGSGSER 744

>HCN3_HUMAN (Q9P1Z3) Potassium/sodium hyperpolarization-activated cyclic|
           nucleotide-gated channel 3
          Length = 774

 Score = 29.3 bits (64), Expect = 4.8
 Identities = 17/42 (40%), Positives = 20/42 (47%), Gaps = 3/42 (7%)
 Frame = -3

Query: 127 PPISGGRR---KGRPLQESGSRAAGRRPAHGFDPREGTGGRR 11
           PP  GGRR   +GRPL  S      R    G   R+G+G  R
Sbjct: 697 PPGGGGRRLGPRGRPLSASQPSLPQRATGDGSPGRKGSGSER 738

>SMR1_PODAN (Q08142) Sporulation minus regulator 1|
          Length = 356

 Score = 29.3 bits (64), Expect = 4.8
 Identities = 18/61 (29%), Positives = 28/61 (45%), Gaps = 7/61 (11%)
 Frame = -2

Query: 383 YQRSVEPHGGILEDLPPNEGREEDV-------EGERQRQEHGHGDHLERVVRELPPMPPH 225
           Y R V+  GG L  L P    +E++       E   +   + HG+ L   +R+LP  P H
Sbjct: 135 YDRDVKYFGGTLFHLNPQVNLDEELPELDDYYEDVDELTNYYHGEKLSHPLRQLPGNPWH 194

Query: 224 R 222
           +
Sbjct: 195 K 195

>Y2887_RHIME (Q92LX6) UPF0176 protein R02887|
          Length = 315

 Score = 29.3 bits (64), Expect = 4.8
 Identities = 26/93 (27%), Positives = 37/93 (39%), Gaps = 8/93 (8%)
 Frame = -2

Query: 452 KCASQTTGRSPCQRGRGGRQEDSYQRSVEPHGGI---LEDLPPNEGREED---VEGERQR 291
           K A   TG   C++     +E  ++      GGI   LE++PP E   E    V  ER  
Sbjct: 185 KIAMYCTGGIRCEKATAFMKEQGFEEVYHLKGGILKYLEEIPPEESLWEGACFVFDERVS 244

Query: 290 QEHG--HGDHLERVVRELPPMPPHRLAPDNQHG 198
             HG   G+H        P  P    +P ++ G
Sbjct: 245 VTHGLQEGEHTLCHACRQPLTPEDLQSPLHEEG 277

>NOP12_GIBZE (Q4IQW0) Nucleolar protein 12|
          Length = 559

 Score = 29.3 bits (64), Expect = 4.8
 Identities = 14/45 (31%), Positives = 20/45 (44%)
 Frame = -2

Query: 395 QEDSYQRSVEPHGGILEDLPPNEGREEDVEGERQRQEHGHGDHLE 261
           ++D     +       ED P +E  +ED + E   QE G GD  E
Sbjct: 58  EDDEVLSEISEELSFEEDGPSDEDEDEDEDEENSEQEDGSGDEQE 102

>DNL3_HUMAN (P49916) DNA ligase 3 (EC 6.5.1.1) (DNA ligase III)|
           (Polydeoxyribonucleotide synthase [ATP] 3)
          Length = 922

 Score = 29.3 bits (64), Expect = 4.8
 Identities = 14/31 (45%), Positives = 19/31 (61%)
 Frame = -2

Query: 308 EGERQRQEHGHGDHLERVVRELPPMPPHRLA 216
           +GER  Q H +GDH     R L P+ PH++A
Sbjct: 423 DGERV-QVHKNGDHFSYFSRSLKPVLPHKVA 452

>Y4491_AGRT5 (Q8U7F8) UPF0176 protein Atu4491/AGR_L_756|
          Length = 314

 Score = 29.3 bits (64), Expect = 4.8
 Identities = 28/93 (30%), Positives = 36/93 (38%), Gaps = 8/93 (8%)
 Frame = -2

Query: 452 KCASQTTGRSPCQRGRGGRQEDSYQRSVEPHGGI---LEDLPPNEGREED---VEGERQR 291
           K A   TG   C++     +E  +       GGI   LE++P  E   E    V  ER  
Sbjct: 184 KIAMYCTGGIRCEKATAFMKEQGFDEVYHLKGGILKYLEEVPEEESLWEGACFVFDERVS 243

Query: 290 QEHG--HGDHLERVVRELPPMPPHRLAPDNQHG 198
             HG   GDH        P  P  RL+P  + G
Sbjct: 244 VVHGLAEGDHQLCHACRNPITPDVRLSPKFEEG 276

>RYR1_PIG (P16960) Ryanodine receptor 1 (Skeletal muscle-type ryanodine|
            receptor) (RyR1) (RYR-1) (Skeletal muscle calcium release
            channel)
          Length = 5035

 Score = 29.3 bits (64), Expect = 4.8
 Identities = 16/45 (35%), Positives = 23/45 (51%)
 Frame = -2

Query: 347  EDLPPNEGREEDVEGERQRQEHGHGDHLERVVRELPPMPPHRLAP 213
            E+LPP    E + E E+   E+G  +     V + PP PP + AP
Sbjct: 4481 EELPPEPEPEPEPEPEKADAENGEKEE----VPKPPPEPPKKTAP 4521

>VASP_HUMAN (P50552) Vasodilator-stimulated phosphoprotein (VASP)|
          Length = 379

 Score = 29.3 bits (64), Expect = 4.8
 Identities = 16/38 (42%), Positives = 23/38 (60%), Gaps = 2/38 (5%)
 Frame = -2

Query: 335 PNEGREEDVEGERQRQEHGHGDHLERVVREL--PPMPP 228
           PN    E+VE +++RQ+ G  +H+ER V     PP PP
Sbjct: 129 PNGPSPEEVE-QQKRQQPGPSEHIERRVSNAGGPPAPP 165

>RRS1_HUMAN (Q15050) Ribosome biogenesis regulatory protein homolog|
          Length = 365

 Score = 29.3 bits (64), Expect = 4.8
 Identities = 15/37 (40%), Positives = 19/37 (51%)
 Frame = -3

Query: 115 GGRRKGRPLQESGSRAAGRRPAHGFDPREGTGGRRRG 5
           GG+RKG P  + G R  G        P  G GG+R+G
Sbjct: 320 GGKRKGGPPSQGGKRKGGLGGKMNSGP-PGLGGKRKG 355

>ADRB3_MOUSE (P25962) Beta-3 adrenergic receptor (Beta-3 adrenoceptor) (Beta-3|
           adrenoreceptor)
          Length = 400

 Score = 29.3 bits (64), Expect = 4.8
 Identities = 18/37 (48%), Positives = 19/37 (51%), Gaps = 3/37 (8%)
 Frame = +3

Query: 18  PPVPSRGSNPCAGRRPAARLPDS---CKGRPFLLPPL 119
           PP PSR  +P  G  PAA  PD    C  RP  L PL
Sbjct: 248 PPSPSRSPSPATGGTPAA--PDGVPPCGRRPARLLPL 282

>YP158_YEAST (Q99299) Protein YPL158C|
          Length = 758

 Score = 28.9 bits (63), Expect = 6.3
 Identities = 15/46 (32%), Positives = 25/46 (54%)
 Frame = -2

Query: 347 EDLPPNEGREEDVEGERQRQEHGHGDHLERVVRELPPMPPHRLAPD 210
           E+   +E  +ED E E ++++ G G +L + V EL  + P R   D
Sbjct: 673 EEDEEDEEDDEDDEEEEEKRKEGEGRNLAKEVDELAELSPMRKQSD 718

>IF2_STRCO (Q8CJQ8) Translation initiation factor IF-2|
          Length = 1033

 Score = 28.9 bits (63), Expect = 6.3
 Identities = 14/36 (38%), Positives = 16/36 (44%)
 Frame = -3

Query: 115 GGRRKGRPLQESGSRAAGRRPAHGFDPREGTGGRRR 8
           GG+R G P Q  G R  G RP +      G  G  R
Sbjct: 198 GGQRPGAPAQRPGGRPGGPRPGNNPFTSGGNAGMAR 233

>SNUT1_RAT (Q5XIW8) U4/U6.U5 tri-snRNP-associated protein 1 (Squamous cell|
           carcinoma antigen recognized by T-cells 1) (SART-1)
           (rSART-1)
          Length = 806

 Score = 28.9 bits (63), Expect = 6.3
 Identities = 15/37 (40%), Positives = 19/37 (51%)
 Frame = -3

Query: 118 SGGRRKGRPLQESGSRAAGRRPAHGFDPREGTGGRRR 8
           SGG R+ R  +    R +GRR A   + R G  GR R
Sbjct: 48  SGGERRKRSRERGAERGSGRRGAEA-EARSGAHGRER 83

>SNUT1_MOUSE (Q9Z315) U4/U6.U5 tri-snRNP-associated protein 1 (Squamous cell|
           carcinoma antigen recognized by T-cells 1) (SART-1)
           (mSART-1) (Hypoxia-associated factor)
          Length = 806

 Score = 28.9 bits (63), Expect = 6.3
 Identities = 15/37 (40%), Positives = 19/37 (51%)
 Frame = -3

Query: 118 SGGRRKGRPLQESGSRAAGRRPAHGFDPREGTGGRRR 8
           SGG R+ R  +    R +GRR A   + R G  GR R
Sbjct: 48  SGGERRKRSRERGSERGSGRRGAEA-EARSGAHGRER 83

>DNL3_MOUSE (P97386) DNA ligase 3 (EC 6.5.1.1) (DNA ligase III)|
           (Polydeoxyribonucleotide synthase [ATP] 3)
          Length = 1015

 Score = 28.5 bits (62), Expect = 8.2
 Identities = 14/31 (45%), Positives = 18/31 (58%)
 Frame = -2

Query: 308 EGERQRQEHGHGDHLERVVRELPPMPPHRLA 216
           +GER  Q H  GDH     R L P+ PH++A
Sbjct: 514 DGERV-QVHKKGDHFSYFSRSLKPVLPHKVA 543


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 62,001,551
Number of Sequences: 219361
Number of extensions: 1269286
Number of successful extensions: 4932
Number of sequences better than 10.0: 26
Number of HSP's better than 10.0 without gapping: 4493
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4898
length of database: 80,573,946
effective HSP length: 102
effective length of database: 58,199,124
effective search space used: 2793557952
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)