>UBE11_WHEAT (P20973) Ubiquitin-activating enzyme E1 1|
          Length = 1051

 Score =  122 bits (305), Expect = 6e-28
 Identities = 64/82 (78%), Positives = 65/82 (79%)
 Frame = +2

Query: 218 MLPRKREIVAGEVEDLQKKXXXXXXXXXXXXXXXXMARRGNEIDEDLHSRQLAVYGRETM 397
           MLPRKREIVAGEVEDLQKK                MA RGNEIDEDLHSRQLAVYGRETM
Sbjct: 1   MLPRKREIVAGEVEDLQKKTRAGEGEVTREEGDAAMAGRGNEIDEDLHSRQLAVYGRETM 60

Query: 398 KRLFGSNVLVSGLQGLGAEIAR 463
           KRLFGSNVLVSGLQGLGAEIA+
Sbjct: 61  KRLFGSNVLVSGLQGLGAEIAK 82

>UBE12_WHEAT (P31251) Ubiquitin-activating enzyme E1 2|
          Length = 1051

 Score =  119 bits (299), Expect = 3e-27
 Identities = 63/82 (76%), Positives = 64/82 (78%)
 Frame = +2

Query: 218 MLPRKREIVAGEVEDLQKKXXXXXXXXXXXXXXXXMARRGNEIDEDLHSRQLAVYGRETM 397
           MLPRKREIVAGEVEDLQKK                MA RGNEIDEDLHSRQLAVYGRETM
Sbjct: 1   MLPRKREIVAGEVEDLQKKTRAGEGEATREEGDAAMAGRGNEIDEDLHSRQLAVYGRETM 60

Query: 398 KRLFGSNVLVSGLQGLGAEIAR 463
           K LFGSNVLVSGLQGLGAEIA+
Sbjct: 61  KPLFGSNVLVSGLQGLGAEIAK 82

>UBE13_WHEAT (P31252) Ubiquitin-activating enzyme E1 3|
          Length = 1053

 Score = 73.9 bits (180), Expect = 2e-13
 Identities = 36/41 (87%), Positives = 39/41 (95%)
 Frame = +2

Query: 341 EIDEDLHSRQLAVYGRETMKRLFGSNVLVSGLQGLGAEIAR 463
           EIDEDLHSRQLAVYGRETM+RLF S+VLVSGL GLGAEIA+
Sbjct: 45  EIDEDLHSRQLAVYGRETMRRLFASDVLVSGLNGLGAEIAK 85

>UBE1_RABIT (Q29504) Ubiquitin-activating enzyme E1|
          Length = 1058

 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 32/49 (65%), Positives = 38/49 (77%), Gaps = 2/49 (4%)
 Frame = +2

Query: 323 MARRGNE--IDEDLHSRQLAVYGRETMKRLFGSNVLVSGLQGLGAEIAR 463
           MA+ G+E  IDE L+SRQL V G E MKRL  S+VLVSGL+GLG EIA+
Sbjct: 41  MAKNGSEADIDEGLYSRQLYVLGHEAMKRLQTSSVLVSGLRGLGVEIAK 89

>UBE1_HUMAN (P22314) Ubiquitin-activating enzyme E1 (A1S9 protein)|
          Length = 1058

 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 32/49 (65%), Positives = 38/49 (77%), Gaps = 2/49 (4%)
 Frame = +2

Query: 323 MARRGNE--IDEDLHSRQLAVYGRETMKRLFGSNVLVSGLQGLGAEIAR 463
           MA+ G+E  IDE L+SRQL V G E MKRL  S+VLVSGL+GLG EIA+
Sbjct: 41  MAKNGSEADIDEGLYSRQLYVLGHEAMKRLQTSSVLVSGLRGLGVEIAK 89

>UBE1_MOUSE (Q02053) Ubiquitin-activating enzyme E1 1|
          Length = 1058

 Score = 55.5 bits (132), Expect = 7e-08
 Identities = 31/49 (63%), Positives = 37/49 (75%), Gaps = 2/49 (4%)
 Frame = +2

Query: 323 MARRGNE--IDEDLHSRQLAVYGRETMKRLFGSNVLVSGLQGLGAEIAR 463
           MA+ G+E  IDE L+SRQL V G E MK L  S+VLVSGL+GLG EIA+
Sbjct: 41  MAKNGSEADIDESLYSRQLYVLGHEAMKMLQTSSVLVSGLRGLGVEIAK 89

>UBE1L_HUMAN (P41226) Ubiquitin-activating enzyme E1 homolog (D8)|
          Length = 1011

 Score = 53.1 bits (126), Expect = 3e-07
 Identities = 25/40 (62%), Positives = 33/40 (82%)
 Frame = +2

Query: 344 IDEDLHSRQLAVYGRETMKRLFGSNVLVSGLQGLGAEIAR 463
           +DE+L+SRQL V G   M+R+ G+ VLVSGLQGLGAE+A+
Sbjct: 10  LDEELYSRQLYVLGSPAMQRIQGARVLVSGLQGLGAEVAK 49

>UBA1_YEAST (P22515) Ubiquitin-activating enzyme E1 1|
          Length = 1024

 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 25/41 (60%), Positives = 32/41 (78%)
 Frame = +2

Query: 341 EIDEDLHSRQLAVYGRETMKRLFGSNVLVSGLQGLGAEIAR 463
           EIDE L+SRQL V G+E M ++  SNVL+ GL+GLG EIA+
Sbjct: 13  EIDESLYSRQLYVLGKEAMLKMQTSNVLILGLKGLGVEIAK 53

>UBA1_SCHPO (O94609) Ubiquitin-activating enzyme E1 1 (Poly(A)+ RNA transport|
           protein 3)
          Length = 1012

 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 25/42 (59%), Positives = 31/42 (73%)
 Frame = +2

Query: 338 NEIDEDLHSRQLAVYGRETMKRLFGSNVLVSGLQGLGAEIAR 463
           N IDE L+SRQL V G E MK++  SNVL+ G +GLG EIA+
Sbjct: 13  NTIDEGLYSRQLYVLGHEAMKQMSQSNVLIIGCKGLGVEIAK 54

>ULE1A_HUMAN (Q9UBE0) Ubiquitin-like 1-activating enzyme E1A (SUMO-1-activating|
           enzyme subunit 1)
          Length = 346

 Score = 40.4 bits (93), Expect = 0.002
 Identities = 19/35 (54%), Positives = 26/35 (74%)
 Frame = +2

Query: 359 HSRQLAVYGRETMKRLFGSNVLVSGLQGLGAEIAR 463
           + RQ+ ++G E  KRL  S VL+ GL+GLGAEIA+
Sbjct: 19  YDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAK 53

>ULE1A_MOUSE (Q9R1T2) Ubiquitin-like 1-activating enzyme E1A (SUMO-1-activating|
           enzyme subunit 1)
          Length = 350

 Score = 40.4 bits (93), Expect = 0.002
 Identities = 18/35 (51%), Positives = 26/35 (74%)
 Frame = +2

Query: 359 HSRQLAVYGRETMKRLFGSNVLVSGLQGLGAEIAR 463
           + RQ+ ++G E  KRL  S VL+ G++GLGAEIA+
Sbjct: 23  YDRQIRLWGLEAQKRLRASRVLIVGMKGLGAEIAK 57

>CP2D6_HUMAN (P10635) Cytochrome P450 2D6 (EC 1.14.14.1) (CYPIID6) (P450-DB1)|
           (Debrisoquine 4-hydroxylase)
          Length = 497

 Score = 30.8 bits (68), Expect = 1.8
 Identities = 22/49 (44%), Positives = 26/49 (53%)
 Frame = -2

Query: 406 EALHGLAAIDGELATVQVLVDLVPPPCHGCVSFLPGRLPLPGAGFLLQV 260
           EAL  LA I   +A   +LVDL+         + PG LPLPG G LL V
Sbjct: 4   EALVPLAVI---VAIFLLLVDLMHRRQRWAARYPPGPLPLPGLGNLLHV 49

>YBHO_SALTY (Q8ZQP4) Putative cardiolipin synthetase ybhO (EC 2.7.8.-)|
           (Cardiolipin synthase) (CL synthase)
          Length = 413

 Score = 30.0 bits (66), Expect = 3.1
 Identities = 16/39 (41%), Positives = 18/39 (46%), Gaps = 5/39 (12%)
 Frame = +1

Query: 355 PAQSPARRLWPRDHEA-----PLRLQRPRLWTSGSRCRD 456
           P QSPARR W R H+A     P   Q   +W      RD
Sbjct: 168 PGQSPARRWWKRHHQAEENRHPGEAQALFVWRDNEEHRD 206

>YBHO_SALTI (Q8Z883) Putative cardiolipin synthetase ybhO (EC 2.7.8.-)|
           (Cardiolipin synthase) (CL synthase)
          Length = 413

 Score = 30.0 bits (66), Expect = 3.1
 Identities = 16/39 (41%), Positives = 18/39 (46%), Gaps = 5/39 (12%)
 Frame = +1

Query: 355 PAQSPARRLWPRDHEA-----PLRLQRPRLWTSGSRCRD 456
           P QSPARR W R H+A     P   Q   +W      RD
Sbjct: 168 PGQSPARRWWKRHHQAEENRHPGEAQALFVWRDNEEHRD 206

>CP2DQ_RAT (P10634) Cytochrome P450 2D26 (EC 1.14.14.1) (CYPIID26) (P450-DB2)|
           (P450-CMF2) (Debrisoquine 4-hydroxylase)
          Length = 500

 Score = 29.3 bits (64), Expect = 5.2
 Identities = 16/32 (50%), Positives = 19/32 (59%)
 Frame = -2

Query: 355 VLVDLVPPPCHGCVSFLPGRLPLPGAGFLLQV 260
           +LVDLV         + PG +PLPG G LLQV
Sbjct: 21  LLVDLVHRHKFWTAHYPPGPVPLPGLGNLLQV 52

>CP2DH_MACFA (Q29488) Cytochrome P450 2D17 (EC 1.14.14.1) (CYPIID17)|
          Length = 497

 Score = 29.3 bits (64), Expect = 5.2
 Identities = 18/47 (38%), Positives = 23/47 (48%)
 Frame = -2

Query: 400 LHGLAAIDGELATVQVLVDLVPPPCHGCVSFLPGRLPLPGAGFLLQV 260
           L  L  +   +A   +LVDL+         + PG LPLPG G LL V
Sbjct: 3   LDALVPLAVTVAIFLLLVDLMHRRQRWAARYPPGPLPLPGLGNLLHV 49

>CP2D6_PANTR (Q2XNC8) Cytochrome P450 2D6 (EC 1.14.14.1) (CYPIID6)|
          Length = 497

 Score = 29.3 bits (64), Expect = 5.2
 Identities = 21/49 (42%), Positives = 25/49 (51%)
 Frame = -2

Query: 406 EALHGLAAIDGELATVQVLVDLVPPPCHGCVSFLPGRLPLPGAGFLLQV 260
           EAL  LA I   +    +LVDL+         + PG LPLPG G LL V
Sbjct: 4   EALVPLAVI---VTIFLLLVDLMHRRQRWAARYPPGPLPLPGLGNLLHV 49

>CP2D6_PANPA (Q2XNC9) Cytochrome P450 2D6 (EC 1.14.14.1) (CYPIID6)|
          Length = 497

 Score = 29.3 bits (64), Expect = 5.2
 Identities = 21/49 (42%), Positives = 25/49 (51%)
 Frame = -2

Query: 406 EALHGLAAIDGELATVQVLVDLVPPPCHGCVSFLPGRLPLPGAGFLLQV 260
           EAL  LA I   +    +LVDL+         + PG LPLPG G LL V
Sbjct: 4   EALVPLAVI---VTIFLLLVDLMHRRQRWAARYPPGPLPLPGLGNLLHV 49

>CP2DP_PIG (O46658) Cytochrome P450 2D25 (EC 1.14.14.-) (CYPIID25) (Vitamin|
           D(3) 25-hydroxylase)
          Length = 499

 Score = 29.3 bits (64), Expect = 5.2
 Identities = 15/32 (46%), Positives = 19/32 (59%)
 Frame = -2

Query: 355 VLVDLVPPPCHGCVSFLPGRLPLPGAGFLLQV 260
           +LVDL+         + PG +PLPG G LLQV
Sbjct: 20  LLVDLMHRRSRWAPRYPPGPMPLPGLGNLLQV 51

>CP2DJ_CALJA (O18992) Cytochrome P450 2D19 (EC 1.14.14.1) (CYPIID19) (P450|
           CM2D-1)
          Length = 497

 Score = 28.5 bits (62), Expect = 8.9
 Identities = 17/47 (36%), Positives = 23/47 (48%)
 Frame = -2

Query: 400 LHGLAAIDGELATVQVLVDLVPPPCHGCVSFLPGRLPLPGAGFLLQV 260
           L  L  +   +A   +LVDL+         + PG +PLPG G LL V
Sbjct: 3   LDALVPLAVTVAIFVLLVDLMHRRQRWAARYPPGPMPLPGLGNLLHV 49

>UBA3_SCHPO (Q09765) NEDD8-activating enzyme E1 catalytic subunit (EC 6.3.2.-)|
           (Ubiquitin-activating enzyme E1 3)
          Length = 444

 Score = 28.5 bits (62), Expect = 8.9
 Identities = 12/25 (48%), Positives = 16/25 (64%)
 Frame = +2

Query: 389 ETMKRLFGSNVLVSGLQGLGAEIAR 463
           ET+K  F S +L+ G  GLG EI +
Sbjct: 37  ETLKSAFSSKILIIGAGGLGCEILK 61

>LEU1_STRCO (O31046) 2-isopropylmalate synthase (EC 2.3.3.13)|
           (Alpha-isopropylmalate synthase) (Alpha-IPM synthetase)
          Length = 573

 Score = 28.5 bits (62), Expect = 8.9
 Identities = 13/46 (28%), Positives = 21/46 (45%)
 Frame = +3

Query: 9   CNPVLQSHPRNPRRTVPRLLPSPTRQANPRFRGGRTRWI*RGSSRR 146
           C  V+ ++   P R +   LP+   ++ P     R  W+ R  SRR
Sbjct: 200 CEAVMDTYQPGPGREIILNLPATVERSTPSTHADRFEWMGRNLSRR 245


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 53,710,588
Number of Sequences: 219361
Number of extensions: 914468
Number of successful extensions: 3547
Number of sequences better than 10.0: 22
Number of HSP's better than 10.0 without gapping: 3345
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3544
length of database: 80,573,946
effective HSP length: 102
effective length of database: 58,199,124
effective search space used: 3026354448
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)