ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | bastl44c11 |
|---|---|
| Clone Library Name | barley_pub |
>MRP3_ARATH (Q9LK64) Multidrug resistance-associated protein 3 (EC 3.6.3.44)| (Glutathione S-conjugate transporting ATPase 3) (ATP-energized glutathione S-conjugate pump 3) Length = 1514 Score = 224 bits (571), Expect = 8e-59 Identities = 109/148 (73%), Positives = 127/148 (85%) Frame = +2 Query: 2 LGIPLESGKVLSALATFRVLQEPIYNLPDTISMMIQTKVSLDRIASFLCLEELPTDAVDR 181 LGIPLESGK+LSALATFR+LQEPIYNLPDTISM++QTKVSLDR+AS+LCL+ L D V+R Sbjct: 571 LGIPLESGKILSALATFRILQEPIYNLPDTISMIVQTKVSLDRLASYLCLDNLQPDIVER 630 Query: 182 LPSGSSNVAIEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILG 361 LP GSS+VA+EV N SWD S PTLKD+NF+ GM+VAVCGTVGSGKSSLLS +LG Sbjct: 631 LPKGSSDVAVEVINSTLSWDVSSSNPTLKDINFKVFPGMKVAVCGTVGSGKSSLLSSLLG 690 Query: 362 EVPKLSGEVKTCGTMAYVSQTAWIQSGK 445 EVPK+SG +K CGT AYV+Q+ WIQSGK Sbjct: 691 EVPKVSGSLKVCGTKAYVAQSPWIQSGK 718 Score = 32.7 bits (73), Expect = 0.43 Identities = 16/53 (30%), Positives = 29/53 (54%), Gaps = 1/53 (1%) Frame = +2 Query: 245 SPELP-TLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEVKTCG 400 +P +P L+ + + G+R + G GSGKS+L+ + V +GE++ G Sbjct: 1279 APHMPLVLRGITCTFKGGLRTGIVGRTGSGKSTLIQTLFRIVEPSAGEIRIDG 1331
>MRP8_ARATH (Q8VZZ4) Multidrug resistance-associated protein 8 (EC 3.6.3.44)| (Glutathione S-conjugate transporting ATPase 8) (ATP-energized glutathione S-conjugate pump 8) Length = 1466 Score = 222 bits (565), Expect = 4e-58 Identities = 105/148 (70%), Positives = 127/148 (85%) Frame = +2 Query: 2 LGIPLESGKVLSALATFRVLQEPIYNLPDTISMMIQTKVSLDRIASFLCLEELPTDAVDR 181 L IPLESGK+L+ALATFR+LQ PIY LP+TISM++QTKVSL+RIASFLCL++L D V R Sbjct: 532 LKIPLESGKILAALATFRILQGPIYKLPETISMIVQTKVSLNRIASFLCLDDLQQDVVGR 591 Query: 182 LPSGSSNVAIEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILG 361 LPSGSS +A+E+SNG FSWD S +PTL+D+NF+ QGM VA+CGTVGSGKSSLLS ILG Sbjct: 592 LPSGSSEMAVEISNGTFSWDDSSPIPTLRDMNFKVSQGMNVAICGTVGSGKSSLLSSILG 651 Query: 362 EVPKLSGEVKTCGTMAYVSQTAWIQSGK 445 EVPK+SG +K CG AY++Q+ WIQSGK Sbjct: 652 EVPKISGNLKVCGRKAYIAQSPWIQSGK 679 Score = 29.3 bits (64), Expect = 4.7 Identities = 16/52 (30%), Positives = 25/52 (48%), Gaps = 1/52 (1%) Frame = +2 Query: 248 PELP-TLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEVKTCG 400 P LP L L G++ + G G GKS+L+ + V +GE++ G Sbjct: 1230 PHLPMVLHGLTCTFPGGLKTGIVGRTGCGKSTLIQTLFRIVEPAAGEIRIDG 1281
>MRP7_ARATH (Q9LK62) Multidrug resistance-associated protein 7 (EC 3.6.3.44)| (Glutathione S-conjugate transporting ATPase 7) (ATP-energized glutathione S-conjugate pump 7) Length = 1493 Score = 218 bits (555), Expect = 5e-57 Identities = 102/148 (68%), Positives = 125/148 (84%) Frame = +2 Query: 2 LGIPLESGKVLSALATFRVLQEPIYNLPDTISMMIQTKVSLDRIASFLCLEELPTDAVDR 181 L IPLESGK+++ALATFR+LQ PIY LPDTISM++QTKVSLDRIA+FLCL++L D ++R Sbjct: 555 LKIPLESGKIIAALATFRILQTPIYKLPDTISMIVQTKVSLDRIATFLCLDDLQQDGMER 614 Query: 182 LPSGSSNVAIEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILG 361 LPSGSS + +EVSNG FSWD S +PTLKD+ F+ GM +A+CGTVGSGKSSLLS ILG Sbjct: 615 LPSGSSKMDVEVSNGAFSWDDSSPIPTLKDIRFKIPHGMNIAICGTVGSGKSSLLSSILG 674 Query: 362 EVPKLSGEVKTCGTMAYVSQTAWIQSGK 445 EVPK+SG +K CG AY++Q+ WIQSGK Sbjct: 675 EVPKISGNLKVCGRKAYIAQSPWIQSGK 702 Score = 31.2 bits (69), Expect = 1.2 Identities = 16/52 (30%), Positives = 27/52 (51%), Gaps = 1/52 (1%) Frame = +2 Query: 248 PELP-TLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEVKTCG 400 P LP L+ L + G++ + G G GKS+L+ + V +GE++ G Sbjct: 1252 PHLPMVLRGLTCTFRGGLKTGIVGRTGCGKSTLIQTLFRIVEPAAGEIRIDG 1303
>MRP5_ARATH (Q7GB25) Multidrug resistance-associated protein 5 (EC 3.6.3.44)| (Glutathione S-conjugate transporting ATPase 5) (ATP-energized glutathione S-conjugate pump 5) Length = 1514 Score = 191 bits (486), Expect = 6e-49 Identities = 94/147 (63%), Positives = 112/147 (76%) Frame = +2 Query: 2 LGIPLESGKVLSALATFRVLQEPIYNLPDTISMMIQTKVSLDRIASFLCLEELPTDAVDR 181 LG L +G VLSALATFR+LQEP+ N PD +SMM QTKVSLDRI+ FL EEL DA Sbjct: 553 LGTQLTAGGVLSALATFRILQEPLRNFPDLVSMMAQTKVSLDRISGFLQEEELQEDATVV 612 Query: 182 LPSGSSNVAIEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILG 361 +P G SN+AIE+ +G F WD PTL + + ++GMRVAVCGTVGSGKSS +SCILG Sbjct: 613 IPRGLSNIAIEIKDGVFCWDPFSSRPTLSGIQMKVEKGMRVAVCGTVGSGKSSFISCILG 672 Query: 362 EVPKLSGEVKTCGTMAYVSQTAWIQSG 442 E+PK+SGEV+ CGT YVSQ+AWIQSG Sbjct: 673 EIPKISGEVRICGTTGYVSQSAWIQSG 699
>MRP9_ARATH (Q9M1C7) Multidrug resistance-associated protein 9 (EC 3.6.3.44)| (Glutathione S-conjugate transporting ATPase 9) (ATP-energized glutathione S-conjugate pump 9) Length = 1490 Score = 158 bits (400), Expect = 5e-39 Identities = 77/147 (52%), Positives = 102/147 (69%) Frame = +2 Query: 2 LGIPLESGKVLSALATFRVLQEPIYNLPDTISMMIQTKVSLDRIASFLCLEELPTDAVDR 181 +G+ L +G VLSALATF++LQ PI+ LPD +S ++Q+KVS DRIAS+L E DAV+ Sbjct: 561 MGVKLTAGAVLSALATFQMLQSPIFGLPDLLSALVQSKVSADRIASYLQQSETQKDAVEY 620 Query: 182 LPSGSSNVAIEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILG 361 + +++E+ NG FSW+ PTL D+ + + GM+VAVCG VGSGKSSLLS ILG Sbjct: 621 CSKDHTELSVEIENGAFSWEPESSRPTLDDIELKVKSGMKVAVCGAVGSGKSSLLSSILG 680 Query: 362 EVPKLSGEVKTCGTMAYVSQTAWIQSG 442 E+ KL G V+ G AYV Q+ WI SG Sbjct: 681 EIQKLKGTVRVSGKQAYVPQSPWILSG 707
>MRP15_ARATH (Q7FB56) Putative multidrug resistance-associated protein 15 (EC| 3.6.3.44) (Glutathione S-conjugate transporting ATPase 15) (ATP-energized glutathione S-conjugate pump 15) Length = 1037 Score = 155 bits (391), Expect = 6e-38 Identities = 75/147 (51%), Positives = 101/147 (68%) Frame = +2 Query: 2 LGIPLESGKVLSALATFRVLQEPIYNLPDTISMMIQTKVSLDRIASFLCLEELPTDAVDR 181 +G+ L +G VLSALATF++LQ PI+ LPD +S ++Q+KVS DRIAS+L E DAV+ Sbjct: 145 MGVKLTAGAVLSALATFQMLQSPIFGLPDLLSALVQSKVSADRIASYLQQSETQKDAVEY 204 Query: 182 LPSGSSNVAIEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILG 361 + + ++E+ NG FSW+ PTL D+ + + GM+VA+CG VGSGKSSL S ILG Sbjct: 205 CSNDHTEFSVEIENGAFSWEPESSRPTLDDIELKVKSGMKVAICGAVGSGKSSLPSSILG 264 Query: 362 EVPKLSGEVKTCGTMAYVSQTAWIQSG 442 E+ KL G V+ G AYV Q+ WI SG Sbjct: 265 EIQKLKGTVRVSGKQAYVPQSPWILSG 291
>MRP6_ARATH (Q8LGU1) Multidrug resistance-associated protein 6 precursor (EC| 3.6.3.44) (Glutathione S-conjugate transporting ATPase 6) (ATP-energized glutathione S-conjugate pump 6) Length = 1295 Score = 144 bits (364), Expect = 8e-35 Identities = 67/144 (46%), Positives = 100/144 (69%) Frame = +2 Query: 11 PLESGKVLSALATFRVLQEPIYNLPDTISMMIQTKVSLDRIASFLCLEELPTDAVDRLPS 190 PL + + + LAT RV+ EP+ +PD IS +IQ VS R+ +FL +EL D ++R Sbjct: 373 PLNASTIFTVLATLRVMSEPVKIIPDAISAIIQGNVSFQRLNNFLLDDELKMDEIERSGL 432 Query: 191 GSSNVAIEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVP 370 +S A+++ G F W+ ++PTL++++ + + G +VAVCG VG+GKSSLL +LGE+P Sbjct: 433 DASGTAVDIQVGNFGWEPETKIPTLRNIHLEIKHGQKVAVCGPVGAGKSSLLHAVLGEIP 492 Query: 371 KLSGEVKTCGTMAYVSQTAWIQSG 442 K+SG VK G++AYVSQT+WIQSG Sbjct: 493 KVSGTVKVFGSIAYVSQTSWIQSG 516
>MRP10_ARATH (Q9LZJ5) Multidrug resistance-associated protein 10 (EC 3.6.3.44)| (Glutathione S-conjugate transporting ATPase 10) (ATP-energized glutathione S-conjugate pump 10) Length = 1539 Score = 144 bits (363), Expect = 1e-34 Identities = 65/147 (44%), Positives = 101/147 (68%) Frame = +2 Query: 2 LGIPLESGKVLSALATFRVLQEPIYNLPDTISMMIQTKVSLDRIASFLCLEELPTDAVDR 181 LG+ L++G V + F++LQEPI P ++ + Q +SL R+ +++ EL + V+R Sbjct: 570 LGVKLDAGTVFTTTTIFKILQEPIRTFPQSMISLSQAMISLGRLDAYMMSRELSEETVER 629 Query: 182 LPSGSSNVAIEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILG 361 NVA+E+ +G FSWD + P ++++NF+ ++G A+ GTVGSGKSSLL+ +LG Sbjct: 630 SQGCDGNVAVEIKDGSFSWDDEDDEPAIENINFEVKKGELAAIVGTVGSGKSSLLASVLG 689 Query: 362 EVPKLSGEVKTCGTMAYVSQTAWIQSG 442 E+ KLSG+V+ CGT AYV+QT+WIQ+G Sbjct: 690 EMHKLSGKVRVCGTTAYVAQTSWIQNG 716
>MRP4_ARATH (Q7DM58) Multidrug resistance-associated protein 4 (EC 3.6.3.44)| (Glutathione S-conjugate transporting ATPase 4) (ATP-energized glutathione S-conjugate pump 4) Length = 1516 Score = 142 bits (358), Expect = 4e-34 Identities = 65/147 (44%), Positives = 99/147 (67%) Frame = +2 Query: 2 LGIPLESGKVLSALATFRVLQEPIYNLPDTISMMIQTKVSLDRIASFLCLEELPTDAVDR 181 LG+ L++G V + F++LQEPI P ++ + Q +SL R+ S++ +EL DAV+R Sbjct: 572 LGVKLDAGTVFTTTTIFKILQEPIRTFPQSMISLSQAMISLGRLDSYMMSKELSEDAVER 631 Query: 182 LPSGSSNVAIEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILG 361 N A+EV +G FSWD P L D+NF+ ++G A+ GTVGSGKSSLL+ +LG Sbjct: 632 ALGCDGNTAVEVRDGSFSWDDEDNEPALSDINFKVKKGELTAIVGTVGSGKSSLLASVLG 691 Query: 362 EVPKLSGEVKTCGTMAYVSQTAWIQSG 442 E+ ++SG+V+ CG+ YV+QT+WI++G Sbjct: 692 EMHRISGQVRVCGSTGYVAQTSWIENG 718
>MRP14_ARATH (Q9LYS2) Multidrug resistance-associated protein 14 (EC 3.6.3.44)| (Glutathione S-conjugate transporting ATPase 14) (ATP-energized glutathione S-conjugate pump 14) Length = 1389 Score = 122 bits (306), Expect = 4e-28 Identities = 69/150 (46%), Positives = 97/150 (64%), Gaps = 3/150 (2%) Frame = +2 Query: 2 LGIPLESGKVLSALATFRVLQEPIYNLPDTISMMIQTKVSLDRIASFLCLEELPTDAVDR 181 L IPL + V + +AT R++Q+P+ +PD I + IQ KV+ RIA+FL EL R Sbjct: 467 LDIPLRASNVFTFVATLRLVQDPVRMIPDVIGVTIQAKVAFSRIATFLEAPELQGGERRR 526 Query: 182 LPSGSSNV-AIEVSNGCFSWD--GSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSC 352 N AI + + FSW+ GS + P L++++ + + G +VAVCG VGSGKS+LL+ Sbjct: 527 KQRSEGNQNAIIIKSASFSWEEKGSTK-PNLRNVSLEVKFGEKVAVCGEVGSGKSTLLAA 585 Query: 353 ILGEVPKLSGEVKTCGTMAYVSQTAWIQSG 442 ILGE P +SG + GT+AYVSQTAWIQ+G Sbjct: 586 ILGETPCVSGTIDFYGTIAYVSQTAWIQTG 615
>MRP2_RABIT (Q28689) Canalicular multispecific organic anion transporter 1| (ATP-binding cassette sub-family C member 2) (Multidrug resistance-associated protein 2) (Canalicular multidrug resistance protein) (Epithelial basolateral chloride conductance reg Length = 1564 Score = 114 bits (285), Expect = 1e-25 Identities = 59/143 (41%), Positives = 91/143 (63%) Frame = +2 Query: 14 LESGKVLSALATFRVLQEPIYNLPDTISMMIQTKVSLDRIASFLCLEELPTDAVDRLPSG 193 L++ K +++ F +L+ P+ LP+ IS M+Q VS+DR+ +L ++L T A+ R P+ Sbjct: 572 LDAEKAFTSITLFNILRFPMSMLPNVISAMLQASVSVDRLEKYLSGDDLDTSAIQRDPNF 631 Query: 194 SSNVAIEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPK 373 A++ S F+WD + E PT++++N G VAV GTVGSGKSSL+S +LGE+ Sbjct: 632 DK--AVQFSEASFTWDRNLE-PTIRNVNLDIMPGQLVAVVGTVGSGKSSLMSAMLGEMEN 688 Query: 374 LSGEVKTCGTMAYVSQTAWIQSG 442 + G + GT AYV Q +WIQ+G Sbjct: 689 VHGHITIKGTTAYVPQQSWIQNG 711 Score = 35.4 bits (80), Expect = 0.066 Identities = 24/96 (25%), Positives = 42/96 (43%), Gaps = 1/96 (1%) Frame = +2 Query: 116 VSLDRIASFLCLEELPTDAVDRLPSGSSNVAIEVSNGCFSWDGSPELP-TLKDLNFQAQQ 292 V+++RI ++ +E D+ P E+ + PEL LK +N + Sbjct: 1265 VAVERITEYIKVENEAPWVTDKRPPAGWPHKGEIQFSNYQVRYRPELDLVLKGINCDIKS 1324 Query: 293 GMRVAVCGTVGSGKSSLLSCILGEVPKLSGEVKTCG 400 ++ V G G+GKSSL +C+ + G + G Sbjct: 1325 MEKIGVVGRTGAGKSSLTNCLFRILEAAGGHITIDG 1360
>MRP3_RAT (O88563) Canalicular multispecific organic anion transporter 2| (Multidrug resistance-associated protein 3) (MRP-like protein 2) (MLP-2) Length = 1522 Score = 110 bits (276), Expect = 1e-24 Identities = 68/143 (47%), Positives = 88/143 (61%), Gaps = 1/143 (0%) Frame = +2 Query: 14 LESGKVLSALATFRVLQEPIYNLPDTISMMIQTKVSLDRIASFLCLEELPTDAVDRLPSG 193 L++ K +L+ F +L+ P+ LP IS M QT VSL RI FL +EL V+R + Sbjct: 561 LDAEKAFVSLSLFNILKIPLNLLPQLISGMTQTSVSLKRIQDFLNQDELDPQCVER-KTI 619 Query: 194 SSNVAIEVSNGCFSWDGSPELP-TLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVP 370 S AI + NG FSW S +LP TL +N Q +G VAV G VG GKSSL+S +LGE+ Sbjct: 620 SPGRAITIHNGTFSW--SKDLPPTLHSINIQIPKGALVAVVGPVGCGKSSLVSALLGEME 677 Query: 371 KLSGEVKTCGTMAYVSQTAWIQS 439 KL G V G++AYV Q AWIQ+ Sbjct: 678 KLEGAVSVKGSVAYVPQQAWIQN 700 Score = 34.3 bits (77), Expect = 0.15 Identities = 15/42 (35%), Positives = 23/42 (54%) Frame = +2 Query: 263 LKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEV 388 LK+L Q G +V + G G+GKSS+ C+ + GE+ Sbjct: 1301 LKNLTLHVQGGEKVGIVGRTGAGKSSMTLCLFRILEAAEGEI 1342
>MRP1_MACFA (Q864R9) Multidrug resistance-associated protein 1 (ATP-binding| cassette sub-family C member 1) (Leukotriene C(4) transporter) (LTC4 transporter) Length = 1531 Score = 109 bits (272), Expect = 4e-24 Identities = 63/144 (43%), Positives = 86/144 (59%), Gaps = 2/144 (1%) Frame = +2 Query: 14 LESGKVLSALATFRVLQEPIYNLPDTISMMIQTKVSLDRIASFLCLEELPTDAVDRLP-- 187 L++ K +LA F +L+ P+ LP IS ++Q VSL R+ FL EEL D+++R P Sbjct: 577 LDAQKAFVSLALFNILRFPLNILPMVISSIVQASVSLKRLRIFLSHEELEPDSIERRPVK 636 Query: 188 SGSSNVAIEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEV 367 G +I V N F+W S + PTL + F +G VAV G VG GKSSLLS +L E+ Sbjct: 637 DGGDTNSITVRNATFTWARS-DPPTLNGITFSIPEGALVAVVGQVGCGKSSLLSALLAEM 695 Query: 368 PKLSGEVKTCGTMAYVSQTAWIQS 439 K+ G V G++AYV Q AWIQ+ Sbjct: 696 DKVEGHVALKGSVAYVPQQAWIQN 719
>MRP1_CHICK (Q5F364) Multidrug resistance-associated protein 1 (ATP-binding| cassette sub-family C member 1) (Leukotriene C(4) transporter) (LTC4 transporter) Length = 1525 Score = 109 bits (272), Expect = 4e-24 Identities = 61/142 (42%), Positives = 87/142 (61%) Frame = +2 Query: 14 LESGKVLSALATFRVLQEPIYNLPDTISMMIQTKVSLDRIASFLCLEELPTDAVDRLPSG 193 L++ K +LA F +L+ P+ LP IS +++ VSL R+ FL EEL D++ R P Sbjct: 576 LDAQKAFVSLALFNILRFPLNILPMVISSIVEASVSLKRLRVFLSHEELDPDSIIRGPIT 635 Query: 194 SSNVAIEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPK 373 ++ +I V N FSW + + P+L +NF +G +AV G VG GKSSLLS +LGE+ K Sbjct: 636 NAEGSIVVKNATFSWSKT-DPPSLNSINFTVPEGSLIAVVGQVGCGKSSLLSALLGEMDK 694 Query: 374 LSGEVKTCGTMAYVSQTAWIQS 439 G V G++AYV Q AWIQ+ Sbjct: 695 KEGYVVVKGSIAYVPQQAWIQN 716
>MRP1_CANFA (Q6UR05) Multidrug resistance-associated protein 1 (ATP-binding| cassette sub-family C member 1) (Leukotriene C(4) transporter) (LTC4 transporter) Length = 1531 Score = 108 bits (271), Expect = 5e-24 Identities = 63/144 (43%), Positives = 86/144 (59%), Gaps = 2/144 (1%) Frame = +2 Query: 14 LESGKVLSALATFRVLQEPIYNLPDTISMMIQTKVSLDRIASFLCLEELPTDAVDRLP-- 187 L++ K +LA F +L+ P+ LP IS ++Q VSL R+ FL EEL D+++R P Sbjct: 577 LDAQKAFVSLALFNILRFPLNILPMVISSIVQASVSLKRLRIFLSHEELEPDSIERRPVK 636 Query: 188 SGSSNVAIEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEV 367 G +I V N F+W S + PTL + F +G VAV G VG GKSSLLS +L E+ Sbjct: 637 DGGGANSITVKNATFTWARS-DPPTLSGITFSIPEGSLVAVVGQVGCGKSSLLSALLAEM 695 Query: 368 PKLSGEVKTCGTMAYVSQTAWIQS 439 K+ G V G++AYV Q AWIQ+ Sbjct: 696 DKVEGHVAIKGSVAYVPQQAWIQN 719
>MRP1_MOUSE (O35379) Multidrug resistance-associated protein 1 (ATP-binding| cassette sub-family C member 1) (Leukotriene C(4) transporter) (LTC4 transporter) Length = 1528 Score = 108 bits (270), Expect = 6e-24 Identities = 64/144 (44%), Positives = 87/144 (60%), Gaps = 2/144 (1%) Frame = +2 Query: 14 LESGKVLSALATFRVLQEPIYNLPDTISMMIQTKVSLDRIASFLCLEELPTDAVDR--LP 187 L++ K +LA F +L+ P+ LP IS ++Q VSL R+ FL EEL D+++R + Sbjct: 578 LDAKKAFVSLALFNILRFPLNILPMVISSIVQASVSLKRLRIFLSHEELEPDSIERRSIK 637 Query: 188 SGSSNVAIEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEV 367 SG N +I V N F+W E PTL + F +G VAV G VG GKSSLLS +L E+ Sbjct: 638 SGEGN-SITVKNATFTW-ARGEPPTLNGITFSIPEGALVAVVGQVGCGKSSLLSALLAEM 695 Query: 368 PKLSGEVKTCGTMAYVSQTAWIQS 439 K+ G V G++AYV Q AWIQ+ Sbjct: 696 DKVEGHVTLKGSVAYVPQQAWIQN 719
>MRP1_HUMAN (P33527) Multidrug resistance-associated protein 1 (ATP-binding| cassette sub-family C member 1) (Leukotriene C(4) transporter) (LTC4 transporter) Length = 1531 Score = 107 bits (266), Expect = 2e-23 Identities = 62/144 (43%), Positives = 85/144 (59%), Gaps = 2/144 (1%) Frame = +2 Query: 14 LESGKVLSALATFRVLQEPIYNLPDTISMMIQTKVSLDRIASFLCLEELPTDAVDRLP-- 187 L++ +LA F +L+ P+ LP IS ++Q VSL R+ FL EEL D+++R P Sbjct: 577 LDAQTAFVSLALFNILRFPLNILPMVISSIVQASVSLKRLRIFLSHEELEPDSIERRPVK 636 Query: 188 SGSSNVAIEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEV 367 G +I V N F+W S + PTL + F +G VAV G VG GKSSLLS +L E+ Sbjct: 637 DGGGTNSITVRNATFTWARS-DPPTLNGITFSIPEGALVAVVGQVGCGKSSLLSALLAEM 695 Query: 368 PKLSGEVKTCGTMAYVSQTAWIQS 439 K+ G V G++AYV Q AWIQ+ Sbjct: 696 DKVEGHVAIKGSVAYVPQQAWIQN 719
>MRP1_RAT (Q8CG09) Multidrug resistance-associated protein 1 (ATP-binding| cassette sub-family C member 1) (Leukotriene C(4) transporter) (LTC4 transporter) Length = 1532 Score = 106 bits (265), Expect = 2e-23 Identities = 62/144 (43%), Positives = 84/144 (58%), Gaps = 2/144 (1%) Frame = +2 Query: 14 LESGKVLSALATFRVLQEPIYNLPDTISMMIQTKVSLDRIASFLCLEELPTDAVDR--LP 187 L++ K +LA F +L+ P+ LP IS ++Q VSL R+ FL EEL D+++R + Sbjct: 578 LDAKKAFVSLALFNILRFPLNILPMVISSIVQASVSLKRLRIFLSHEELEPDSIERWSIK 637 Query: 188 SGSSNVAIEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEV 367 G +I V N F+W E PTL + F G VAV G VG GKSSLLS +L E+ Sbjct: 638 DGGGMNSITVKNATFTW-ARDEPPTLNGITFAIPDGALVAVVGQVGCGKSSLLSALLAEM 696 Query: 368 PKLSGEVKTCGTMAYVSQTAWIQS 439 K+ G V G++AYV Q AWIQ+ Sbjct: 697 DKVEGHVTLKGSVAYVPQQAWIQN 720
>MRP1_BOVIN (Q8HXQ5) Multidrug resistance-associated protein 1 (ATP-binding| cassette sub-family C member 1) (Leukotriene C(4) transporter) (LTC4 transporter) Length = 1530 Score = 106 bits (265), Expect = 2e-23 Identities = 62/145 (42%), Positives = 89/145 (61%), Gaps = 3/145 (2%) Frame = +2 Query: 14 LESGKVLSALATFRVLQEPIYNLPDTISMMIQTKVSLDRIASFLCLEELPTDAVDRLP-- 187 L++ K +LA F +L+ P+ LP IS ++Q VSL R+ FL E+L D++ R P Sbjct: 577 LDAQKAFVSLALFNILRFPLNILPMVISSIVQASVSLKRLRVFLSHEDLDPDSIQRRPIK 636 Query: 188 -SGSSNVAIEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGE 364 +G++N +I V N F+W + + PTL + F +G VAV G VG GKSSLLS +L E Sbjct: 637 DAGATN-SITVKNATFTWARN-DPPTLHGITFSVPEGSLVAVVGQVGCGKSSLLSALLAE 694 Query: 365 VPKLSGEVKTCGTMAYVSQTAWIQS 439 + K+ G V G++AYV Q AWIQ+ Sbjct: 695 MDKVEGHVTVKGSVAYVPQQAWIQN 719
>YAWB_SCHPO (Q10185) Probable ATP-dependent permease C3F10.11c| Length = 1478 Score = 106 bits (264), Expect = 3e-23 Identities = 57/140 (40%), Positives = 83/140 (59%), Gaps = 5/140 (3%) Frame = +2 Query: 29 VLSALATFRVLQEPIYNLPDTISMMIQTKVSLDRIASFLCLEELPTDAVDRLPSGS--SN 202 V + L+ F +LQ P+ LP +S +++ V++ RI FL EL ++AV R P+ S Sbjct: 531 VFACLSLFNLLQFPLTMLPIVVSSVLEASVAISRIYGFLTAGELDSNAVQRYPANKEPSG 590 Query: 203 VAIEVSNGCFSWDGSPEL---PTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPK 373 V +E+ G FSW G + PTL+D++F A++G + G VG GKSSLL LG + K Sbjct: 591 VCLEIKKGTFSWSGPGQNAAEPTLRDIDFVARRGELCCIVGKVGMGKSSLLEACLGNMQK 650 Query: 374 LSGEVKTCGTMAYVSQTAWI 433 SG V CG++AY +Q WI Sbjct: 651 HSGSVFRCGSIAYAAQQPWI 670 Score = 28.5 bits (62), Expect = 8.1 Identities = 26/96 (27%), Positives = 49/96 (51%), Gaps = 4/96 (4%) Frame = +2 Query: 116 VSLDRIASFLCL-EELPTDAVD-RLPSG-SSNVAIEVSNGCFSWDGSPELP-TLKDLNFQ 283 VS++R+ ++ L E P+ D R P G S+ AI+ + +S LP L D++ Sbjct: 1205 VSVERMLEYIGLPSEAPSIIPDHRPPEGWPSHGAIKFDH--YSVRYRENLPLVLNDISVN 1262 Query: 284 AQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEVK 391 + ++ + G G+GKS+L + + SG+++ Sbjct: 1263 IKPQEKIGIVGRTGAGKSTLTLALFRLIEPTSGDIQ 1298
>MRP3_HUMAN (O15438) Canalicular multispecific organic anion transporter 2| (Multidrug resistance-associated protein 3) (Multi-specific organic anion transporter-D) (MOAT-D) Length = 1527 Score = 105 bits (262), Expect = 5e-23 Identities = 63/143 (44%), Positives = 89/143 (62%), Gaps = 1/143 (0%) Frame = +2 Query: 14 LESGKVLSALATFRVLQEPIYNLPDTISMMIQTKVSLDRIASFLCLEELPTDAVDRLPSG 193 L++ K +++ F +L+ P+ LP IS + Q VSL RI FL EEL +V+R + Sbjct: 563 LDAEKAFVSVSLFNILRLPLNMLPQLISNLTQASVSLKRIQQFLSQEELDPQSVER-KTI 621 Query: 194 SSNVAIEVSNGCFSWDGSPELP-TLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVP 370 S AI + +G F+W + +LP TL L+ Q +G VAV G VG GKSSL+S +LGE+ Sbjct: 622 SPGYAITIHSGTFTW--AQDLPPTLHSLDIQVPKGALVAVVGPVGCGKSSLVSALLGEME 679 Query: 371 KLSGEVKTCGTMAYVSQTAWIQS 439 KL G+V G++AYV Q AWIQ+ Sbjct: 680 KLEGKVHMKGSVAYVPQQAWIQN 702 Score = 35.0 bits (79), Expect = 0.086 Identities = 15/46 (32%), Positives = 25/46 (54%) Frame = +2 Query: 263 LKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEVKTCG 400 L+DL+ G +V + G G+GKSS+ C+ + GE++ G Sbjct: 1306 LRDLSLHVHGGEKVGIVGRTGAGKSSMTLCLFRILEAAKGEIRIDG 1351
>MRP6_RAT (O88269) Multidrug resistance-associated protein 6 (ATP-binding| cassette sub-family C member 6) (MRP-like protein 1) (MLP-1) Length = 1502 Score = 103 bits (256), Expect = 3e-22 Identities = 57/143 (39%), Positives = 84/143 (58%), Gaps = 1/143 (0%) Frame = +2 Query: 14 LESGKVLSALATFRVLQEPIYNLPDTISMMIQTKVSLDRIASFLCLEELPTDAVDRLPSG 193 +++ K L +L + LP ++ ++Q +VS DR+A+FLCLEE+ + + PS Sbjct: 561 MDAEKAFVTLTVLSILNKAQAFLPFSVHCLVQARVSFDRLAAFLCLEEVDPNGMVLSPSR 620 Query: 194 -SSNVAIEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVP 370 SS I + NG F+W P L +N QG +AV G VG+GKSSLLS +LGE+ Sbjct: 621 CSSKDRISIHNGTFAWSQESP-PCLHGINLTVPQGCLLAVVGPVGAGKSSLLSALLGELL 679 Query: 371 KLSGEVKTCGTMAYVSQTAWIQS 439 K+ G V G++AYV Q AW+Q+ Sbjct: 680 KVEGSVSIEGSVAYVPQEAWVQN 702 Score = 32.7 bits (73), Expect = 0.43 Identities = 31/119 (26%), Positives = 55/119 (46%), Gaps = 5/119 (4%) Frame = +2 Query: 2 LGIPLESGKVLSALATFRVLQEPIYNLPDTISMMIQTKVSLDRIASFLCLEELPTDAVDR 181 L L V +AL + LQ + + D + M V+++R+ ++ P +A R Sbjct: 1196 LSAGLAGFSVSAALQVTQTLQWVVRSWTDLENSM----VAVERVQDYV---HTPKEAPWR 1248 Query: 182 LPSGSSN----VAIEVSNGCFSWDGSPELP-TLKDLNFQAQQGMRVAVCGTVGSGKSSL 343 LPS ++ ++ F PELP ++ ++ + G +V + G G+GKSSL Sbjct: 1249 LPSSAAQPLWPCGGQIEFRDFGLRHRPELPMAVQGVSLKIHAGEKVGIVGRTGAGKSSL 1307
>MRP2_RAT (Q63120) Canalicular multispecific organic anion transporter 1| (ATP-binding cassette sub-family C member 2) (Multidrug resistance-associated protein 2) (Canalicular multidrug resistance protein) Length = 1541 Score = 102 bits (254), Expect = 4e-22 Identities = 55/143 (38%), Positives = 88/143 (61%) Frame = +2 Query: 14 LESGKVLSALATFRVLQEPIYNLPDTISMMIQTKVSLDRIASFLCLEELPTDAVDRLPSG 193 L + K +++ F +L+ P+ LP S ++Q VS+DR+ +L ++L T A+ R+ Sbjct: 570 LNAEKAFTSITLFNILRFPLSMLPMVTSSILQASVSVDRLERYLGGDDLDTSAIRRV--S 627 Query: 194 SSNVAIEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPK 373 + + A++ S F+WD E T++D+N + G VAV GTVGSGKSSL+S +LGE+ Sbjct: 628 NFDKAVKFSEASFTWDPDLEA-TIQDVNLDIKPGQLVAVVGTVGSGKSSLVSAMLGEMEN 686 Query: 374 LSGEVKTCGTMAYVSQTAWIQSG 442 + G + G+ AYV Q +WIQ+G Sbjct: 687 VHGHITIQGSTAYVPQQSWIQNG 709 Score = 37.7 bits (86), Expect = 0.013 Identities = 24/92 (26%), Positives = 43/92 (46%), Gaps = 1/92 (1%) Frame = +2 Query: 116 VSLDRIASFLCLEELPTDAVDRLPSGSSNVAIEVSNGCFSWDGSPELP-TLKDLNFQAQQ 292 V+++RI+ ++ +E D+ P E+ + PEL LK + + Sbjct: 1263 VAVERISEYINVENEAPWVTDKRPPADWPRHGEIQFNNYQVRYRPELDLVLKGITCNIKS 1322 Query: 293 GMRVAVCGTVGSGKSSLLSCILGEVPKLSGEV 388 G +V V G G+GKSSL +C+ + G++ Sbjct: 1323 GEKVGVVGRTGAGKSSLTNCLFRILESAGGQI 1354
>MRP2_MOUSE (Q8VI47) Canalicular multispecific organic anion transporter 1| (ATP-binding cassette sub-family C member 2) Length = 1543 Score = 102 bits (254), Expect = 4e-22 Identities = 56/143 (39%), Positives = 86/143 (60%) Frame = +2 Query: 14 LESGKVLSALATFRVLQEPIYNLPDTISMMIQTKVSLDRIASFLCLEELPTDAVDRLPSG 193 L + K +++ F +L+ P+ LP IS +IQ VS+DR+ +L ++L A+ + Sbjct: 572 LNAEKAFTSITLFNILRFPLAMLPMVISSVIQASVSVDRLERYLGSDDLDLSAIRHVCHF 631 Query: 194 SSNVAIEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPK 373 A++ S F+WD E T++D+N + G VAV GTVGSGKSSL+S +LGE+ Sbjct: 632 DK--AVQFSEASFTWDRDLEA-TIQDVNLDIKPGQLVAVVGTVGSGKSSLISAMLGEMEN 688 Query: 374 LSGEVKTCGTMAYVSQTAWIQSG 442 + G + G++AYV Q AWIQ+G Sbjct: 689 VHGHITIKGSIAYVPQQAWIQNG 711 Score = 33.1 bits (74), Expect = 0.33 Identities = 22/92 (23%), Positives = 41/92 (44%), Gaps = 1/92 (1%) Frame = +2 Query: 116 VSLDRIASFLCLEELPTDAVDRLPSGSSNVAIEVSNGCFSWDGSPELP-TLKDLNFQAQQ 292 V+++RI ++ ++ D+ P E+ + PEL LK + + Sbjct: 1265 VAVERINEYINVDNEAPWVTDKKPPADWPKKGEIQFNNYQVRYRPELDLVLKGITCNIKS 1324 Query: 293 GMRVAVCGTVGSGKSSLLSCILGEVPKLSGEV 388 +V V G G+GKSSL +C+ + G++ Sbjct: 1325 TEKVGVVGRTGAGKSSLTNCLFRILESAGGQI 1356
>MRP6_MOUSE (Q9R1S7) Multidrug resistance-associated protein 6 (ATP-binding| cassette sub-family C member 6) Length = 1498 Score = 101 bits (252), Expect = 7e-22 Identities = 57/143 (39%), Positives = 82/143 (57%), Gaps = 1/143 (0%) Frame = +2 Query: 14 LESGKVLSALATFRVLQEPIYNLPDTISMMIQTKVSLDRIASFLCLEEL-PTDAVDRLPS 190 +++ K L +L + LP ++ ++Q +VS DR+A+FLCLEE+ P + Sbjct: 561 MDAEKAFVTLTVLSILNKAQAFLPFSVHCIVQARVSFDRLAAFLCLEEVDPNGMIASNSR 620 Query: 191 GSSNVAIEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVP 370 SS I V NG F+W P L +N QG +AV G VG+GKSSLLS +LGE+ Sbjct: 621 RSSKDRISVHNGTFAWSQESP-PCLHGINLTVPQGCLLAVVGPVGAGKSSLLSALLGELL 679 Query: 371 KLSGEVKTCGTMAYVSQTAWIQS 439 K+ G V G++AYV Q AW+Q+ Sbjct: 680 KVEGSVSIEGSVAYVPQEAWVQN 702 Score = 30.4 bits (67), Expect = 2.1 Identities = 28/110 (25%), Positives = 53/110 (48%), Gaps = 5/110 (4%) Frame = +2 Query: 29 VLSALATFRVLQEPIYNLPDTISMMIQTKVSLDRIASFLCLEELPTDAVDRLPSGSSN-- 202 V +AL + LQ + + D + M V+++R+ + +P +A RLP+ ++ Sbjct: 1201 VSAALQVTQTLQWVVRSWTDLENSM----VAVERVQDYA---RIPKEAPWRLPTCAAQPL 1253 Query: 203 --VAIEVSNGCFSWDGSPELP-TLKDLNFQAQQGMRVAVCGTVGSGKSSL 343 ++ F PELP ++ ++ + G +V + G G+GKSSL Sbjct: 1254 WPCGGQIEFRDFGLRHRPELPLAVQGVSLKIHAGEKVGIVGRTGAGKSSL 1303
>YCFI_YEAST (P39109) Metal resistance protein YCF1 (Yeast cadmium factor 1)| Length = 1515 Score = 101 bits (251), Expect = 1e-21 Identities = 57/147 (38%), Positives = 87/147 (59%), Gaps = 4/147 (2%) Frame = +2 Query: 14 LESGKVLSALATFRVLQEPIYNLPDTISMMIQTKVSLDRIASFLCLEELPTDAVDRLPSG 193 L + V AL F +L P+ +P ++ I+ VS+ R+ +F EEL D+V RLP Sbjct: 559 LTTDLVFPALTLFNLLSFPLMIIPMVLNSFIEASVSIGRLFTFFTNEELQPDSVQRLPKV 618 Query: 194 SS--NVAIEVSNGC-FSWDGSPELPT-LKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILG 361 + +VAI + + F W PE LK++NFQA++G + G VGSGK++LLSC+LG Sbjct: 619 KNIGDVAINIGDDATFLWQRKPEYKVALKNINFQAKKGNLTCIVGKVGSGKTALLSCMLG 678 Query: 362 EVPKLSGEVKTCGTMAYVSQTAWIQSG 442 ++ ++ G G++AYVSQ WI +G Sbjct: 679 DLFRVKGFATVHGSVAYVSQVPWIMNG 705 Score = 29.6 bits (65), Expect = 3.6 Identities = 24/93 (25%), Positives = 39/93 (41%), Gaps = 2/93 (2%) Frame = +2 Query: 116 VSLDRIASFLCLE-ELPTDAVDRLPSGSSNVAIEVSNGCFSWDGSPELP-TLKDLNFQAQ 289 VS++RI + L+ E P P ++ +S PEL LK +N + Sbjct: 1238 VSVERIKEYADLKSEAPLIVEGHRPPKEWPSQGDIKFNNYSTRYRPELDLVLKHINIHIK 1297 Query: 290 QGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEV 388 +V + G G+GKSSL + + G + Sbjct: 1298 PNEKVGIVGRTGAGKSSLTLALFRMIEASEGNI 1330
>MRP2_ARATH (Q42093) Multidrug resistance-associated protein 2 (EC 3.6.3.44)| (Glutathione S-conjugate transporting ATPase 2) (ATP-energized glutathione S-conjugate pump 2) Length = 1623 Score = 100 bits (249), Expect = 2e-21 Identities = 57/148 (38%), Positives = 83/148 (56%), Gaps = 4/148 (2%) Frame = +2 Query: 2 LGIPLESGKVLSALATFRVLQEPIYNLPDTISMMIQTKVSLDRIASFLCLEE---LPTDA 172 LG L + ++L+ F VL+ P++ LP+ I+ ++ VSL R+ L EE LP Sbjct: 547 LGGDLTPARAFTSLSLFAVLRFPLFMLPNIITQVVNANVSLKRLEEVLATEERILLPNPP 606 Query: 173 VDRLPSGSSNVAIEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSC 352 ++ AI + NG FSWD + PTL ++N G VAV G+ G GK+SL+S Sbjct: 607 IE-----PGEPAISIRNGYFSWDSKGDRPTLSNINLDVPLGSLVAVVGSTGEGKTSLISA 661 Query: 353 ILGEVPKLSGEVKTC-GTMAYVSQTAWI 433 ILGE+P S + T G++AYV Q +WI Sbjct: 662 ILGELPATSDAIVTLRGSVAYVPQVSWI 689
>YH85_SCHPO (Q9P5N0) Probable ATP-dependent permease C359.05| Length = 1465 Score = 100 bits (248), Expect = 2e-21 Identities = 54/141 (38%), Positives = 79/141 (56%), Gaps = 6/141 (4%) Frame = +2 Query: 29 VLSALATFRVLQEPIYNLPDTISMMIQTKVSLDRIASFLCLEELPTDAVDRLPSGS--SN 202 V A++ F +LQ P+ LP IS +++ VS+ RI FL +EL + V R P+ Sbjct: 513 VFPAVSLFNLLQFPLAMLPTVISSLLEASVSVSRIYEFLIAQELDYNGVQRFPATEIPHE 572 Query: 203 VAIEVSNGCFSWDGSP----ELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVP 370 + +E+ +G FSW PTL+ +NF A+ G + G VG+GKSSLL +G + Sbjct: 573 ICLEIKSGTFSWSKKTLKQQVTPTLRQINFVAKNGELTCIFGKVGAGKSSLLEACMGNMY 632 Query: 371 KLSGEVKTCGTMAYVSQTAWI 433 K SG V CG++AY +Q WI Sbjct: 633 KNSGSVFQCGSLAYAAQQPWI 653
>MRP1_ARATH (Q9C8G9) Multidrug resistance-associated protein 1 (EC 3.6.3.44)| (Glutathione S-conjugate transporting ATPase 1) (ATP-energized glutathione S-conjugate pump 1) Length = 1622 Score = 99.8 bits (247), Expect = 3e-21 Identities = 57/148 (38%), Positives = 83/148 (56%), Gaps = 4/148 (2%) Frame = +2 Query: 2 LGIPLESGKVLSALATFRVLQEPIYNLPDTISMMIQTKVSLDRIASFLCLEE---LPTDA 172 LG L + ++L+ F VL+ P++ LP+ I+ M+ VSL+R+ L EE LP Sbjct: 547 LGGDLTPARAFTSLSLFSVLRFPLFMLPNIITQMVNANVSLNRLEEVLSTEERVLLPNPP 606 Query: 173 VDRLPSGSSNVAIEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSC 352 ++ AI + NG FSWD + PTL ++N G VAV G+ G GK+SL+S Sbjct: 607 IE-----PGQPAISIRNGYFSWDSKADRPTLSNINLDIPLGSLVAVVGSTGEGKTSLISA 661 Query: 353 ILGEVPKLSGEVKTC-GTMAYVSQTAWI 433 +LGE+P S T G++AYV Q +WI Sbjct: 662 MLGELPARSDATVTLRGSVAYVPQVSWI 689 Score = 30.0 bits (66), Expect = 2.8 Identities = 27/97 (27%), Positives = 50/97 (51%), Gaps = 7/97 (7%) Frame = +2 Query: 119 SLDRIASFLCLEELPTDAV-----DRLPSG-SSNVAIEVSNGCFSWDGSPELP-TLKDLN 277 S++R+ +++ E+P++A +R P G S+ +I+ + + PELP L ++ Sbjct: 1204 SVERVGNYI---EIPSEAPLVIENNRPPPGWPSSGSIKFEDVVLRY--RPELPPVLHGVS 1258 Query: 278 FQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEV 388 F +V + G G+GKSSLL+ + V G + Sbjct: 1259 FLISPMDKVGIVGRTGAGKSSLLNALFRIVELEKGRI 1295
>MRP6_HUMAN (O95255) Multidrug resistance-associated protein 6 (ATP-binding| cassette sub-family C member 6) (Anthracycline resistance-associated protein) (Multi-specific organic anion transporter-E) (MOAT-E) Length = 1503 Score = 99.0 bits (245), Expect = 5e-21 Identities = 56/144 (38%), Positives = 80/144 (55%), Gaps = 2/144 (1%) Frame = +2 Query: 14 LESGKVLSALATFRVLQEPIYNLPDTISMMIQTKVSLDRIASFLCLEELPTDAVDRLPSG 193 + + K L +L + LP +I ++Q +VS DR+ +FLCLEE+ VD SG Sbjct: 562 MNAEKAFVTLTVLNILNKAQAFLPFSIHSLVQARVSFDRLVTFLCLEEVDPGVVDSSSSG 621 Query: 194 SS--NVAIEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEV 367 S+ I + + F+W P L +N QG +AV G VG+GKSSLLS +LGE+ Sbjct: 622 SAAGKDCITIHSATFAWSQESP-PCLHRINLTVPQGCLLAVVGPVGAGKSSLLSALLGEL 680 Query: 368 PKLSGEVKTCGTMAYVSQTAWIQS 439 K+ G V G +AYV Q AW+Q+ Sbjct: 681 SKVEGFVSIEGAVAYVPQEAWVQN 704 Score = 33.1 bits (74), Expect = 0.33 Identities = 32/115 (27%), Positives = 56/115 (48%), Gaps = 5/115 (4%) Frame = +2 Query: 29 VLSALATFRVLQEPIYNLPDTISMMIQTKVSLDRIASFLCLEELPTDAVDRLPSGSSNVA 208 V +AL + LQ + N D + + VS++R+ + P +A RLP+ ++ Sbjct: 1206 VSAALQVTQTLQWVVRNWTDLENSI----VSVERMQDYAWT---PKEAPWRLPTCAAQPP 1258 Query: 209 I----EVSNGCFSWDGSPELP-TLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCIL 358 ++ F PELP ++ ++F+ G +V + G G+GKSSL S +L Sbjct: 1259 WPQGGQIEFRDFGLRYRPELPLAVQGVSFKIHAGEKVGIVGRTGAGKSSLASGLL 1313
>MRP2_HUMAN (Q92887) Canalicular multispecific organic anion transporter 1| (ATP-binding cassette sub-family C member 2) (Multidrug resistance-associated protein 2) (Canalicular multidrug resistance protein) Length = 1545 Score = 99.0 bits (245), Expect = 5e-21 Identities = 54/143 (37%), Positives = 85/143 (59%) Frame = +2 Query: 14 LESGKVLSALATFRVLQEPIYNLPDTISMMIQTKVSLDRIASFLCLEELPTDAVDRLPSG 193 L++ K +++ F +L+ P+ LP IS M+Q VS +R+ +L ++L T A+ Sbjct: 574 LDAQKAFTSITLFNILRFPLSMLPMMISSMLQASVSTERLEKYLGGDDLDTSAIRH--DC 631 Query: 194 SSNVAIEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPK 373 + + A++ S F+W+ E T++D+N G VAV G VGSGKSSL+S +LGE+ Sbjct: 632 NFDKAMQFSEASFTWEHDSEA-TVRDVNLDIMAGQLVAVIGPVGSGKSSLISAMLGEMEN 690 Query: 374 LSGEVKTCGTMAYVSQTAWIQSG 442 + G + GT AYV Q +WIQ+G Sbjct: 691 VHGHITIKGTTAYVPQQSWIQNG 713
>MRP12_ARATH (Q9C8H1) Multidrug resistance-associated protein 12 (EC 3.6.3.44)| (Glutathione S-conjugate transporting ATPase 12) (ATP-energized glutathione S-conjugate pump 12) Length = 1495 Score = 95.1 bits (235), Expect = 7e-20 Identities = 56/145 (38%), Positives = 77/145 (53%), Gaps = 1/145 (0%) Frame = +2 Query: 2 LGIPLESGKVLSALATFRVLQEPIYNLPDTISMMIQTKVSLDRIASFLCLEELPTDAVDR 181 LG L + ++L+ F VL+ P+ LP+ IS + VSL RI L EE Sbjct: 548 LGGDLTPARAFTSLSLFAVLRSPLSTLPNLISQAVNANVSLQRIEELLLSEERILAQNPP 607 Query: 182 LPSGSSNVAIEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILG 361 L G+ AI + NG FSWD PTL D+N + G VA+ G G GK+SL+S +LG Sbjct: 608 LQPGAP--AISIKNGYFSWDSKTSKPTLSDINLEIPVGSLVAIVGGTGEGKTSLISAMLG 665 Query: 362 EVPKL-SGEVKTCGTMAYVSQTAWI 433 E+ + V G++AYV Q +WI Sbjct: 666 ELSHAETSSVDIRGSVAYVPQVSWI 690 Score = 28.9 bits (63), Expect = 6.2 Identities = 15/44 (34%), Positives = 22/44 (50%) Frame = +2 Query: 257 PTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEV 388 P L L+F +V V G G+GKSS+L+ + V G + Sbjct: 1250 PVLHGLSFFVYPSEKVGVVGRTGAGKSSMLNALYRIVELEKGRI 1293
>MRP13_ARATH (Q9C8H0) Multidrug resistance-associated protein 13 (EC 3.6.3.44)| (Glutathione S-conjugate transporting ATPase 13) (ATP-energized glutathione S-conjugate pump 13) Length = 1495 Score = 91.7 bits (226), Expect = 8e-19 Identities = 55/145 (37%), Positives = 78/145 (53%), Gaps = 1/145 (0%) Frame = +2 Query: 2 LGIPLESGKVLSALATFRVLQEPIYNLPDTISMMIQTKVSLDRIASFLCLEELPTDAVDR 181 LG L + ++L+ F VL+ P+ LP+ +S ++ VSL RI L EE Sbjct: 548 LGGDLTPARAFTSLSLFAVLRFPLNMLPNLLSQVVNANVSLQRIEELLLSEERILAQNPP 607 Query: 182 LPSGSSNVAIEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILG 361 L G+ AI + NG FSWD PTL D+N + G VA+ G G GK+SL+S +LG Sbjct: 608 LQPGTP--AISIKNGYFSWDSKTTKPTLSDINLEIPVGTLVAIVGGTGEGKTSLISAMLG 665 Query: 362 EVPKL-SGEVKTCGTMAYVSQTAWI 433 E+ + V G++AYV Q +WI Sbjct: 666 ELSHAETTSVVIRGSVAYVPQVSWI 690 Score = 31.2 bits (69), Expect = 1.2 Identities = 27/97 (27%), Positives = 44/97 (45%), Gaps = 7/97 (7%) Frame = +2 Query: 119 SLDRIASFLCLEELPTDAVDR------LPSGSSNVAIEVSNGCFSW-DGSPELPTLKDLN 277 S++R+ +++ L TD ++ PSG S I+ + + G P P L L Sbjct: 1202 SVERVGNYIDLPSEATDIIENNRPVCGWPSGGS---IKFEDVHLRYRPGLP--PVLHGLT 1256 Query: 278 FQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEV 388 F +V V G G+GKSS+L+ + V G + Sbjct: 1257 FFVSPSEKVGVVGRTGAGKSSMLNALFRIVEVEKGRI 1293
>YBT1_YEAST (P32386) ATP-dependent bile acid permease| Length = 1661 Score = 84.3 bits (207), Expect = 1e-16 Identities = 55/159 (34%), Positives = 80/159 (50%), Gaps = 16/159 (10%) Frame = +2 Query: 5 GIPLESGKVLSALATFRVLQEPIYNLPDTISMMIQTKVSLDRIASFLCLEELPTDAVDRL 184 G L + +AL+ F +L++P+ L D +S ++Q+KVSLDR+ FL E T D+L Sbjct: 628 GEVLTTPVAFTALSLFTLLRDPLDRLSDMLSFVVQSKVSLDRVQDFL--NENDTKKYDQL 685 Query: 185 PSGSSNVAIEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGE 364 + N SWD + LKDLN + + G V G GSGK+SLL +LGE Sbjct: 686 TIDPNGNRFAFENSTISWDKDNQDFKLKDLNIEFKTGKLNVVIGPTGSGKTSLLMALLGE 745 Query: 365 VPKLSGEV----------------KTCGTMAYVSQTAWI 433 + L+G+V T ++AY SQ AW+ Sbjct: 746 MYLLNGKVVVPALEPRQELIVDANGTTNSIAYCSQAAWL 784
>MRP4_HUMAN (O15439) Multidrug resistance-associated protein 4| (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter-B) (MOAT-B) Length = 1325 Score = 83.6 bits (205), Expect = 2e-16 Identities = 53/148 (35%), Positives = 82/148 (55%), Gaps = 1/148 (0%) Frame = +2 Query: 2 LGIPLESGKVLSALATFRVLQEPI-YNLPDTISMMIQTKVSLDRIASFLCLEELPTDAVD 178 LG + + +V A+ + ++ + P I + + VS+ RI +FL L+E+ + Sbjct: 342 LGSVITASRVFVAVTLYGAVRLTVTLFFPSAIERVSEAIVSIRRIQTFLLLDEI-SQRNR 400 Query: 179 RLPSGSSNVAIEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCIL 358 +LPS + + V + WD + E PTL+ L+F + G +AV G VG+GKSSLLS +L Sbjct: 401 QLPSDGKKM-VHVQDFTAFWDKASETPTLQGLSFTVRPGELLAVVGPVGAGKSSLLSAVL 459 Query: 359 GEVPKLSGEVKTCGTMAYVSQTAWIQSG 442 GE+ G V G +AYVSQ W+ SG Sbjct: 460 GELAPSHGLVSVHGRIAYVSQQPWVFSG 487 Score = 28.5 bits (62), Expect = 8.1 Identities = 23/82 (28%), Positives = 41/82 (50%), Gaps = 2/82 (2%) Frame = +2 Query: 116 VSLDRIASFLCLE-ELPTDAVDRLPSGSSNVAIEVSNGCFSWDGSPELP-TLKDLNFQAQ 289 +S++R+ + LE E P + R P + + + + ++ SP P LK L + Sbjct: 1008 ISVERVIEYTDLEKEAPWEYQKRPPPAWPHEGVIIFDNV-NFMYSPGGPLVLKHLTALIK 1066 Query: 290 QGMRVAVCGTVGSGKSSLLSCI 355 +V + G G+GKSSL+S + Sbjct: 1067 SQEKVGIVGRTGAGKSSLISAL 1088
>MRP11_ARATH (Q9SKX0) Multidrug resistance-associated protein 11 (EC 3.6.3.44)| (Glutathione S-conjugate transporting ATPase 11) (ATP-energized glutathione S-conjugate pump 11) Length = 1194 Score = 82.8 bits (203), Expect = 4e-16 Identities = 50/150 (33%), Positives = 81/150 (54%), Gaps = 3/150 (2%) Frame = +2 Query: 2 LGIPLESGKVLSALATFRVLQEPIYNLPDTISMMIQTKVSLDRIASFLCLEELPTDAVDR 181 +G L++ V + LA F L P+ + P I+ +I +S R++ FLC E D Sbjct: 279 MGHQLDAATVFTCLALFNSLISPLNSFPWVINGLIDAFISTRRVSKFLCCLEHSRDFSID 338 Query: 182 LPSGSSNVAIEVSNGCFSWDGSPELP---TLKDLNFQAQQGMRVAVCGTVGSGKSSLLSC 352 S ++A+ V + +W + E T+K ++ + +G VAV G VGSGK+SLL+ Sbjct: 339 SGFTSEDLAVCVEDASCTWSSNVEEDYNLTIKQVSLRVPKGSFVAVIGEVGSGKTSLLNS 398 Query: 353 ILGEVPKLSGEVKTCGTMAYVSQTAWIQSG 442 +LGE+ + G + G++AYV Q W+ SG Sbjct: 399 LLGEMRCVHGSILLNGSVAYVPQVPWLLSG 428 Score = 41.6 bits (96), Expect = 0.001 Identities = 20/48 (41%), Positives = 27/48 (56%) Frame = +2 Query: 257 PTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEVKTCG 400 P L ++F Q GM V V G G+GKSS+L+ + P SGE+ G Sbjct: 973 PALTQISFTIQGGMHVGVIGRTGAGKSSILNALFRLTPVCSGEILVDG 1020
>BPT1_YEAST (P14772) Bile pigment transporter 1| Length = 1559 Score = 82.0 bits (201), Expect = 6e-16 Identities = 54/176 (30%), Positives = 88/176 (50%), Gaps = 33/176 (18%) Frame = +2 Query: 11 PLESGKVLSALATFRVLQEPIYNLPDTISMMIQTKVSLDRIASFLCLEELPTDAVDRL-P 187 PL V +L+ F +L IY++P I+ +I+T VS++R+ SFL +E+ ++R+ P Sbjct: 546 PLSPAIVFPSLSLFNILNSAIYSVPSMINTIIETSVSMERLKSFLLSDEIDDSFIERIDP 605 Query: 188 SGSSNV--AIEVSNGCFSWD----------------------GSPELPTLKDLNFQAQQG 295 S AIE++N F W GS ++ +F+A++G Sbjct: 606 SADERALPAIEMNNITFLWKSKEVLTSSQSGDNLRTDEESIIGSSQIALKNIDHFEAKRG 665 Query: 296 MRVAVCGTVGSGKSSLLSCILGEVPKLSGE--------VKTCGTMAYVSQTAWIQS 439 V V G VG+GKS+ L ILG++P +SG + ++AY SQ +WI + Sbjct: 666 DLVCVVGRVGAGKSTFLKAILGQLPCMSGSRDSIPPKLIIRSSSVAYCSQESWIMN 721
>ABCCB_HUMAN (Q96J66) ATP-binding cassette transporter sub-family C member 11| (Multidrug resistance-associated protein 8) Length = 1382 Score = 69.3 bits (168), Expect = 4e-12 Identities = 55/182 (30%), Positives = 79/182 (43%), Gaps = 35/182 (19%) Frame = +2 Query: 2 LGIPLESGKVLSALATFRVLQEPIYNLPDTISMMIQTKVSLDRIASFLCLEELPTDAVDR 181 L + L + S LA+ +L+ ++ +P + + +K ++ R F L+E P V Sbjct: 408 LKLKLTASMAFSMLASLNLLRLSVFFVPIAVKGLTNSKSAVMRFKKFF-LQESPVFYVQT 466 Query: 182 LPSGSSNVAIEVSNGCFSW--------DGSPEL--------------------------- 256 L S + E + SW +G+ EL Sbjct: 467 LQDPSKALVFEEAT--LSWQQTCPGIVNGALELERNGHASEGMTRPRDALGPEEEGNSLG 524 Query: 257 PTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEVKTCGTMAYVSQTAWIQ 436 P L +N +GM + VCG GSGKSSLLS IL E+ L G V G++AYV Q AWI Sbjct: 525 PELHKINLVVSKGMMLGVCGNTGSGKSSLLSAILEEMHLLEGSVGVQGSLAYVPQQAWIV 584 Query: 437 SG 442 SG Sbjct: 585 SG 586
>L259_DROME (P91660) Probable multidrug resistance-associated protein| lethal(2)03659 (Wunen region A protein) Length = 1290 Score = 68.6 bits (166), Expect = 7e-12 Identities = 45/136 (33%), Positives = 68/136 (50%), Gaps = 15/136 (11%) Frame = +2 Query: 80 LPDTISMMIQTKVSLDRIASFLCLEELPT---------DAVDRLPSGSSNVA------IE 214 +P I Q S+ R+ F+ EEL + D V P ++N A I Sbjct: 358 VPSAIIQTAQFLTSIRRVEQFMQSEELGSSDKSEGPSKDTVPGNPPSNNNEADLLKSAIS 417 Query: 215 VSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEVKT 394 + + WD + TL +N + + G VAV G GSGKSSL+ ILGE+ SG+++ Sbjct: 418 IRDLKAKWDPNSPDYTLSGINLEIKPGSVVAVIGLTGSGKSSLIQAILGELKANSGQLQV 477 Query: 395 CGTMAYVSQTAWIQSG 442 G+++Y SQ +W+ SG Sbjct: 478 NGSLSYTSQESWLFSG 493 Score = 29.6 bits (65), Expect = 3.6 Identities = 13/31 (41%), Positives = 20/31 (64%) Frame = +2 Query: 263 LKDLNFQAQQGMRVAVCGTVGSGKSSLLSCI 355 LK L+F Q +V + G G+GKSSL++ + Sbjct: 1053 LKSLSFVIQPREKVGIVGRTGAGKSSLINAL 1083
>NFT1_YEAST (P36028) ABC transporter NFT1 (New full-length MRP-type transporter| 1) Length = 1558 Score = 68.6 bits (166), Expect = 7e-12 Identities = 46/152 (30%), Positives = 76/152 (50%), Gaps = 16/152 (10%) Frame = +2 Query: 35 SALATFRVLQEPIYNLPDTISMMIQTKVSLDRIASFLCLEELPTDAVDRLPSGSSNVAIE 214 +AL+ F +L+ P+ + T+S++IQ+ +SL+RI +L E T + L ++ E Sbjct: 597 TALSLFAILRTPMDQIASTVSLLIQSFISLERIQDYL--NESETRKYEILEQSNTKFGFE 654 Query: 215 VSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEVKT 394 + W+ + LK+++ + A+ G GSGKSSLL +LGE+ LSG++ Sbjct: 655 --DASMEWEAAETSFKLKNISIDFKLNSLNAIIGPTGSGKSSLLLGLLGELNLLSGKIYV 712 Query: 395 ----------------CGTMAYVSQTAWIQSG 442 +MAY SQT W+ SG Sbjct: 713 PTVESRDDLEIGKDGMTNSMAYCSQTPWLISG 744 Score = 30.0 bits (66), Expect = 2.8 Identities = 11/31 (35%), Positives = 22/31 (70%) Frame = +2 Query: 263 LKDLNFQAQQGMRVAVCGTVGSGKSSLLSCI 355 L +++F+ + G +V + G G+GKSS+++ I Sbjct: 1302 LDNVSFKVKAGTKVGIVGRTGAGKSSIIAAI 1332
>MRP5_HUMAN (O15440) Multidrug resistance-associated protein 5 (Multi-specific| organic anion transporter-C) (MOAT-C) (pABC11) (SMRP) Length = 1437 Score = 65.9 bits (159), Expect = 5e-11 Identities = 29/58 (50%), Positives = 41/58 (70%) Frame = +2 Query: 260 TLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEVKTCGTMAYVSQTAWI 433 TL ++ + Q+G V +CG+VGSGK+SL+S ILG++ L G + GT AYV+Q AWI Sbjct: 577 TLHSIDLEIQEGKLVGICGSVGSGKTSLISAILGQMTLLEGSIAISGTFAYVAQQAWI 634 Score = 34.7 bits (78), Expect = 0.11 Identities = 19/82 (23%), Positives = 39/82 (47%) Frame = +2 Query: 2 LGIPLESGKVLSALATFRVLQEPIYNLPDTISMMIQTKVSLDRIASFLCLEELPTDAVDR 181 LG L + + + + F + + P ++ + + V++DR S +EE+ + Sbjct: 424 LGFDLTAAQAFTVVTVFNSMTFALKVTPFSVKSLSEASVAVDRFKSLFLMEEV--HMIKN 481 Query: 182 LPSGSSNVAIEVSNGCFSWDGS 247 P+ S ++ IE+ N +WD S Sbjct: 482 KPA-SPHIKIEMKNATLAWDSS 502
>CFTR_CANFA (Q5U820) Cystic fibrosis transmembrane conductance regulator (CFTR)| (cAMP-dependent chloride channel) (ATP-binding cassette transporter sub-family C member 7) Length = 1483 Score = 65.1 bits (157), Expect = 8e-11 Identities = 41/117 (35%), Positives = 68/117 (58%), Gaps = 6/117 (5%) Frame = +2 Query: 110 TKVSLDRIASFL------CLEELPTDAVDRLPSGSSNVAIEVSNGCFSWDGSPELPTLKD 271 T+V ++ + +F LE+ ++ DR S N ++ SN FS G+P LKD Sbjct: 390 TEVMMENVTAFWEEGFGELLEKAKENSNDRKISNGDN-SLFFSN--FSLLGTP---VLKD 443 Query: 272 LNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEVKTCGTMAYVSQTAWIQSG 442 +NF+ ++G +AV G+ G+GK+SLL I+GE+ G++K G +++ SQ +WI G Sbjct: 444 INFKIERGQLLAVAGSTGAGKTSLLMMIMGELEPSEGKIKHSGRISFCSQFSWIMPG 500 Score = 35.4 bits (80), Expect = 0.066 Identities = 18/46 (39%), Positives = 28/46 (60%) Frame = +2 Query: 263 LKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEVKTCG 400 L++++F G RV + G GSGKS+LLS +L + GE++ G Sbjct: 1230 LENISFSISPGQRVGLLGRTGSGKSTLLSALL-RLVNTEGEIQIDG 1274
>YHD5_YEAST (P38735) Probable ATP-dependent permease YHL035C| Length = 1592 Score = 65.1 bits (157), Expect = 8e-11 Identities = 47/159 (29%), Positives = 76/159 (47%), Gaps = 19/159 (11%) Frame = +2 Query: 14 LESGKVLSALATFRVLQEPIYNLPDTISMMIQTKVSLDRIASFLCLEELPTDAVDRLPSG 193 L + + L+ F +L+ P+ L + +S + Q+KVSL RI+ FL +++ T+ ++L Sbjct: 601 LNAPLAFTTLSLFTLLKTPLDQLSNMLSFINQSKVSLKRISDFLRMDD--TEKYNQLTIS 658 Query: 194 SSNVAIEVSNGCFSW---DGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGE 364 IE N +W D L LN + Q G + G+ GSGKS+LL +LGE Sbjct: 659 PDKNKIEFKNATLTWNENDSDMNAFKLCGLNIKFQIGKLNLILGSTGSGKSALLLGLLGE 718 Query: 365 VPKLSGEV----------------KTCGTMAYVSQTAWI 433 + +SG + + AY SQ+AW+ Sbjct: 719 LNLISGSIIVPSLEPKHDLIPDCEGLTNSFAYCSQSAWL 757
>MRP5_RAT (Q9QYM0) Multidrug resistance-associated protein 5| Length = 1436 Score = 65.1 bits (157), Expect = 8e-11 Identities = 28/58 (48%), Positives = 42/58 (72%) Frame = +2 Query: 260 TLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEVKTCGTMAYVSQTAWI 433 TL +++ + ++G V +CG+VGSGK+SL+S ILG++ L G + GT AYV+Q AWI Sbjct: 577 TLYNIDLEIEEGKLVGICGSVGSGKTSLISAILGQMTLLEGSIAVSGTFAYVAQQAWI 634 Score = 34.7 bits (78), Expect = 0.11 Identities = 19/82 (23%), Positives = 39/82 (47%) Frame = +2 Query: 2 LGIPLESGKVLSALATFRVLQEPIYNLPDTISMMIQTKVSLDRIASFLCLEELPTDAVDR 181 LG L + + + + F + + P ++ + + V++DR S +EE+ + Sbjct: 424 LGFDLTAAQAFTVVTVFNSMTFALKVTPFSVKSLSEASVAVDRFKSLFLMEEV--HMIKN 481 Query: 182 LPSGSSNVAIEVSNGCFSWDGS 247 P+ S ++ IE+ N +WD S Sbjct: 482 KPA-SPHIKIEMKNATLAWDSS 502
>MRP5_MOUSE (Q9R1X5) Multidrug resistance-associated protein 5 (ABC transporter| MOAT-C) (SMRP) Length = 1436 Score = 64.7 bits (156), Expect = 1e-10 Identities = 28/58 (48%), Positives = 42/58 (72%) Frame = +2 Query: 260 TLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEVKTCGTMAYVSQTAWI 433 TL +++ + ++G V +CG+VGSGK+SL+S ILG++ L G + GT AYV+Q AWI Sbjct: 577 TLYNIDLEIEEGKLVGICGSVGSGKTSLVSAILGQMTLLEGSIAVSGTFAYVAQQAWI 634 Score = 34.3 bits (77), Expect = 0.15 Identities = 19/82 (23%), Positives = 39/82 (47%) Frame = +2 Query: 2 LGIPLESGKVLSALATFRVLQEPIYNLPDTISMMIQTKVSLDRIASFLCLEELPTDAVDR 181 LG L + + + + F + + P ++ + + V++DR S +EE+ + Sbjct: 424 LGFHLTAAQAFTVVTVFNSMTFALKVTPFSVKSLSEASVAVDRFKSLFLMEEV--HMIKN 481 Query: 182 LPSGSSNVAIEVSNGCFSWDGS 247 P+ S ++ IE+ N +WD S Sbjct: 482 KPA-SPHIKIEMKNATLAWDSS 502
>ABC1_SCHPO (Q92337) ATP-binding cassette transporter abc1| Length = 1427 Score = 63.9 bits (154), Expect = 2e-10 Identities = 45/152 (29%), Positives = 75/152 (49%), Gaps = 5/152 (3%) Frame = +2 Query: 2 LGIPLESGKVLSALATFRVLQEPIYNLPDTISMMIQTKVSLDRIASFLCLEELPTDAVDR 181 +G L ++++ F +L+ L IQ KVSL R+ +F+ + +++ Sbjct: 514 MGHQLTPATAFTSISMFGLLRYQFIWLASVSRQFIQFKVSLKRVDNFVYGNMVNDSSIE- 572 Query: 182 LPSGSSNVAIEVSNGCFSWDGSPE--LPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCI 355 S+ + N SW +P L LK+LNF + V G+ GSGKS+L + Sbjct: 573 -----SSDSFVFENTSLSWSPTPSTALFQLKNLNFTIPRNQFTLVVGSTGSGKSTLAMAL 627 Query: 356 LGEVPKLSGEVKT---CGTMAYVSQTAWIQSG 442 LGE+ +SG++ T +AYV Q AW+++G Sbjct: 628 LGELHVISGKMTTPSISQRIAYVPQAAWLRNG 659 Score = 29.6 bits (65), Expect = 3.6 Identities = 15/46 (32%), Positives = 26/46 (56%) Frame = +2 Query: 263 LKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEVKTCG 400 L+D+N + ++A+ G GSGKS++ +L +SG V+ G Sbjct: 1197 LEDINLEILPKEKIAIVGRTGSGKSTMGLTLLRFTMIMSGAVEVDG 1242
>CFTR_PONPY (Q2IBE4) Cystic fibrosis transmembrane conductance regulator (CFTR)| (cAMP-dependent chloride channel) (ATP-binding cassette transporter sub-family C member 7) Length = 1480 Score = 62.8 bits (151), Expect = 4e-10 Identities = 27/62 (43%), Positives = 43/62 (69%) Frame = +2 Query: 257 PTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEVKTCGTMAYVSQTAWIQ 436 P LKD+NF+ ++G +AV G+ G+GK+SLL I+GE+ G++K G +++ SQ +WI Sbjct: 439 PVLKDINFKIERGQLLAVAGSTGAGKTSLLMMIMGELEPSEGKIKHSGRISFCSQFSWIM 498 Query: 437 SG 442 G Sbjct: 499 PG 500 Score = 34.3 bits (77), Expect = 0.15 Identities = 18/46 (39%), Positives = 27/46 (58%) Frame = +2 Query: 263 LKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEVKTCG 400 L++++F G RV + G GSGKS+LLS L + GE++ G Sbjct: 1227 LENISFSISPGQRVGLLGRTGSGKSTLLSAFL-RLLNTEGEIQIDG 1271
>CFTR_PANTR (Q2QLE5) Cystic fibrosis transmembrane conductance regulator (CFTR)| (cAMP-dependent chloride channel) (ATP-binding cassette transporter sub-family C member 7) Length = 1480 Score = 62.8 bits (151), Expect = 4e-10 Identities = 27/62 (43%), Positives = 43/62 (69%) Frame = +2 Query: 257 PTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEVKTCGTMAYVSQTAWIQ 436 P LKD+NF+ ++G +AV G+ G+GK+SLL I+GE+ G++K G +++ SQ +WI Sbjct: 439 PVLKDINFKIERGQLLAVAGSTGAGKTSLLMMIMGELEPSEGKIKHSGRISFCSQFSWIM 498 Query: 437 SG 442 G Sbjct: 499 PG 500 Score = 34.3 bits (77), Expect = 0.15 Identities = 18/46 (39%), Positives = 27/46 (58%) Frame = +2 Query: 263 LKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEVKTCG 400 L++++F G RV + G GSGKS+LLS L + GE++ G Sbjct: 1227 LENISFSISPGQRVGLLGRTGSGKSTLLSAFL-RLLNTEGEIQIDG 1271
>CFTR_HUMAN (P13569) Cystic fibrosis transmembrane conductance regulator (CFTR)| (cAMP-dependent chloride channel) (ATP-binding cassette transporter sub-family C member 7) Length = 1480 Score = 62.8 bits (151), Expect = 4e-10 Identities = 27/62 (43%), Positives = 43/62 (69%) Frame = +2 Query: 257 PTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEVKTCGTMAYVSQTAWIQ 436 P LKD+NF+ ++G +AV G+ G+GK+SLL I+GE+ G++K G +++ SQ +WI Sbjct: 439 PVLKDINFKIERGQLLAVAGSTGAGKTSLLMMIMGELEPSEGKIKHSGRISFCSQFSWIM 498 Query: 437 SG 442 G Sbjct: 499 PG 500 Score = 34.3 bits (77), Expect = 0.15 Identities = 18/46 (39%), Positives = 27/46 (58%) Frame = +2 Query: 263 LKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEVKTCG 400 L++++F G RV + G GSGKS+LLS L + GE++ G Sbjct: 1227 LENISFSISPGQRVGLLGRTGSGKSTLLSAFL-RLLNTEGEIQIDG 1271
>CFTR_CALMO (Q2QLB4) Cystic fibrosis transmembrane conductance regulator (CFTR)| (cAMP-dependent chloride channel) (ATP-binding cassette transporter sub-family C member 7) Length = 1480 Score = 62.8 bits (151), Expect = 4e-10 Identities = 27/62 (43%), Positives = 43/62 (69%) Frame = +2 Query: 257 PTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEVKTCGTMAYVSQTAWIQ 436 P LKD+NF+ ++G +AV G+ G+GK+SLL I+GE+ G++K G +++ SQ +WI Sbjct: 439 PVLKDINFKIERGQLLAVAGSTGAGKTSLLMMIMGELEPSEGKIKHSGRISFCSQFSWIM 498 Query: 437 SG 442 G Sbjct: 499 PG 500 Score = 34.3 bits (77), Expect = 0.15 Identities = 18/46 (39%), Positives = 27/46 (58%) Frame = +2 Query: 263 LKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEVKTCG 400 L++++F G RV + G GSGKS+LLS L + GE++ G Sbjct: 1227 LENISFSISPGQRVGLLGRTGSGKSTLLSAFL-RLLNTEGEIQIDG 1271
>CFTR_CARPS (Q2QLC5) Cystic fibrosis transmembrane conductance regulator (CFTR)| (cAMP-dependent chloride channel) (ATP-binding cassette transporter sub-family C member 7) Length = 1482 Score = 62.8 bits (151), Expect = 4e-10 Identities = 26/62 (41%), Positives = 43/62 (69%) Frame = +2 Query: 257 PTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEVKTCGTMAYVSQTAWIQ 436 P L+D+NFQ ++G +A+ G+ G+GK+SLL +LGE+ G++K G +++ SQ +WI Sbjct: 439 PVLRDINFQIERGQLLAIAGSTGAGKTSLLMMLLGELEPSEGKIKHSGRISFCSQFSWIM 498 Query: 437 SG 442 G Sbjct: 499 PG 500 Score = 35.0 bits (79), Expect = 0.086 Identities = 18/46 (39%), Positives = 28/46 (60%) Frame = +2 Query: 263 LKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEVKTCG 400 L++++F G RV + G GSGKS+LLS +L + GE++ G Sbjct: 1229 LENISFSISPGQRVGLLGRTGSGKSTLLSALL-RLLNTEGEIQIDG 1273
>CFTR_PAPAN (Q9TSP5) Cystic fibrosis transmembrane conductance regulator (CFTR)| (cAMP-dependent chloride channel) (ATP-binding cassette transporter sub-family C member 7) Length = 1481 Score = 62.8 bits (151), Expect = 4e-10 Identities = 27/62 (43%), Positives = 43/62 (69%) Frame = +2 Query: 257 PTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEVKTCGTMAYVSQTAWIQ 436 P LKD+NF+ ++G +AV G+ G+GK+SLL I+GE+ G++K G +++ SQ +WI Sbjct: 439 PVLKDINFKIERGQLLAVAGSTGAGKTSLLMMIMGELEPSEGKIKHSGRISFCSQFSWIM 498 Query: 437 SG 442 G Sbjct: 499 PG 500 Score = 36.6 bits (83), Expect = 0.030 Identities = 19/48 (39%), Positives = 28/48 (58%) Frame = +2 Query: 257 PTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEVKTCG 400 P L++++F G RV + G GSGKS+LLS L + GE++ G Sbjct: 1226 PILENISFSISPGQRVGLLGRTGSGKSTLLSAFL-RLLNTEGEIQIDG 1272
>CFTR_MACNE (Q9TUQ2) Cystic fibrosis transmembrane conductance regulator (CFTR)| (cAMP-dependent chloride channel) (ATP-binding cassette transporter sub-family C member 7) Length = 1481 Score = 62.8 bits (151), Expect = 4e-10 Identities = 27/62 (43%), Positives = 43/62 (69%) Frame = +2 Query: 257 PTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEVKTCGTMAYVSQTAWIQ 436 P LKD+NF+ ++G +AV G+ G+GK+SLL I+GE+ G++K G +++ SQ +WI Sbjct: 439 PVLKDINFKIERGQLLAVAGSTGAGKTSLLMMIMGELEPSEGKIKHSGRISFCSQFSWIM 498 Query: 437 SG 442 G Sbjct: 499 PG 500 Score = 36.6 bits (83), Expect = 0.030 Identities = 19/48 (39%), Positives = 28/48 (58%) Frame = +2 Query: 257 PTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEVKTCG 400 P L++++F G RV + G GSGKS+LLS L + GE++ G Sbjct: 1226 PILENISFSISPGQRVGLLGRTGSGKSTLLSAFL-RLLNTEGEIQIDG 1272
>CFTR_MACMU (Q00553) Cystic fibrosis transmembrane conductance regulator (CFTR)| (cAMP-dependent chloride channel) (ATP-binding cassette transporter sub-family C member 7) Length = 1481 Score = 62.8 bits (151), Expect = 4e-10 Identities = 27/62 (43%), Positives = 43/62 (69%) Frame = +2 Query: 257 PTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEVKTCGTMAYVSQTAWIQ 436 P LKD+NF+ ++G +AV G+ G+GK+SLL I+GE+ G++K G +++ SQ +WI Sbjct: 439 PVLKDINFKIERGQLLAVAGSTGAGKTSLLMMIMGELEPSEGKIKHSGRISFCSQFSWIM 498 Query: 437 SG 442 G Sbjct: 499 PG 500 Score = 36.6 bits (83), Expect = 0.030 Identities = 19/48 (39%), Positives = 28/48 (58%) Frame = +2 Query: 257 PTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEVKTCG 400 P L++++F G RV + G GSGKS+LLS L + GE++ G Sbjct: 1226 PILENISFSISPGQRVGLLGRTGSGKSTLLSAFL-RLLNTEGEIQIDG 1272
>CFTR_MACFU (Q7JII7) Cystic fibrosis transmembrane conductance regulator (CFTR)| (cAMP-dependent chloride channel) (ATP-binding cassette transporter sub-family C member 7) Length = 1481 Score = 62.8 bits (151), Expect = 4e-10 Identities = 27/62 (43%), Positives = 43/62 (69%) Frame = +2 Query: 257 PTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEVKTCGTMAYVSQTAWIQ 436 P LKD+NF+ ++G +AV G+ G+GK+SLL I+GE+ G++K G +++ SQ +WI Sbjct: 439 PVLKDINFKIERGQLLAVAGSTGAGKTSLLMMIMGELEPSEGKIKHSGRISFCSQFSWIM 498 Query: 437 SG 442 G Sbjct: 499 PG 500 Score = 36.6 bits (83), Expect = 0.030 Identities = 19/48 (39%), Positives = 28/48 (58%) Frame = +2 Query: 257 PTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEVKTCG 400 P L++++F G RV + G GSGKS+LLS L + GE++ G Sbjct: 1226 PILENISFSISPGQRVGLLGRTGSGKSTLLSAFL-RLLNTEGEIQIDG 1272
>CFTR_MACFA (Q7JII8) Cystic fibrosis transmembrane conductance regulator (CFTR)| (cAMP-dependent chloride channel) (ATP-binding cassette transporter sub-family C member 7) Length = 1481 Score = 62.8 bits (151), Expect = 4e-10 Identities = 27/62 (43%), Positives = 43/62 (69%) Frame = +2 Query: 257 PTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEVKTCGTMAYVSQTAWIQ 436 P LKD+NF+ ++G +AV G+ G+GK+SLL I+GE+ G++K G +++ SQ +WI Sbjct: 439 PVLKDINFKIERGQLLAVAGSTGAGKTSLLMMIMGELEPSEGKIKHSGRISFCSQFSWIM 498 Query: 437 SG 442 G Sbjct: 499 PG 500 Score = 36.6 bits (83), Expect = 0.030 Identities = 19/48 (39%), Positives = 28/48 (58%) Frame = +2 Query: 257 PTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEVKTCG 400 P L++++F G RV + G GSGKS+LLS L + GE++ G Sbjct: 1226 PILENISFSISPGQRVGLLGRTGSGKSTLLSAFL-RLLNTEGEIQIDG 1272
>CFTR_CALJA (Q2QLF9) Cystic fibrosis transmembrane conductance regulator (CFTR)| (cAMP-dependent chloride channel) (ATP-binding cassette transporter sub-family C member 7) Length = 1481 Score = 62.8 bits (151), Expect = 4e-10 Identities = 27/62 (43%), Positives = 43/62 (69%) Frame = +2 Query: 257 PTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEVKTCGTMAYVSQTAWIQ 436 P LKD+NF+ ++G +AV G+ G+GK+SLL I+GE+ G++K G +++ SQ +WI Sbjct: 439 PVLKDINFKIERGQLLAVAGSTGAGKTSLLMMIMGELEPSEGKIKHSGRISFCSQFSWIM 498 Query: 437 SG 442 G Sbjct: 499 PG 500 Score = 34.3 bits (77), Expect = 0.15 Identities = 18/46 (39%), Positives = 27/46 (58%) Frame = +2 Query: 263 LKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEVKTCG 400 L++++F G RV + G GSGKS+LLS L + GE++ G Sbjct: 1228 LENISFSISPGQRVGLLGRTGSGKSTLLSAFL-RLLNTEGEIQIDG 1272
>CFTR_TRIVU (Q5D1Z7) Cystic fibrosis transmembrane conductance regulator (CFTR)| (cAMP-dependent chloride channel) (ATP-binding cassette transporter sub-family C member 7) Length = 1478 Score = 62.4 bits (150), Expect = 5e-10 Identities = 40/123 (32%), Positives = 68/123 (55%) Frame = +2 Query: 74 YNLPDTISMMIQTKVSLDRIASFLCLEELPTDAVDRLPSGSSNVAIEVSNGCFSWDGSPE 253 YNL T MM D L ++ +++ ++P+G + SN FS G+P Sbjct: 385 YNLTTTDVMMENITAFWDEGFGDLFIKVKQSNSDGKIPNGDHGLFF--SN--FSLLGTP- 439 Query: 254 LPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEVKTCGTMAYVSQTAWI 433 LK+++F+ ++G +AV G+ G+GK+SLL I+GE+ G++K G +++ SQ +WI Sbjct: 440 --VLKNISFKIEKGQLLAVAGSTGAGKTSLLMLIMGELEPSEGKIKHSGRISFCSQFSWI 497 Query: 434 QSG 442 G Sbjct: 498 MPG 500
>CFTR_RABIT (Q00554) Cystic fibrosis transmembrane conductance regulator (CFTR)| (cAMP-dependent chloride channel) (ATP-binding cassette transporter sub-family C member 7) Length = 1480 Score = 61.2 bits (147), Expect = 1e-09 Identities = 38/115 (33%), Positives = 66/115 (57%), Gaps = 4/115 (3%) Frame = +2 Query: 110 TKVSLDRIASFLCLEELPTDAVDRLPSGSSNVAIEVSNG----CFSWDGSPELPTLKDLN 277 T+V +D + +F EE + ++ +S+ ++SNG FS P LKD++ Sbjct: 390 TEVVMDNVTAFW--EEGFGELFEKAKQNNSDR--KISNGDNNLFFSNFSLLGAPVLKDIS 445 Query: 278 FQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEVKTCGTMAYVSQTAWIQSG 442 F+ ++G +AV G+ G+GK+SLL I+GE+ G++K G +++ SQ +WI G Sbjct: 446 FKIERGQLLAVAGSTGAGKTSLLMMIMGELEPSEGKIKHSGRISFCSQFSWIMPG 500 Score = 34.3 bits (77), Expect = 0.15 Identities = 18/46 (39%), Positives = 27/46 (58%) Frame = +2 Query: 263 LKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEVKTCG 400 L++++F G RV + G GSGKS+LLS L + GE++ G Sbjct: 1227 LENISFSISPGQRVGLLGRTGSGKSTLLSAFL-RLLNTEGEIQIDG 1271
>ABCC9_RABIT (P82451) ATP-binding cassette transporter sub-family C member 9| (Sulfonylurea receptor 2) Length = 1549 Score = 61.2 bits (147), Expect = 1e-09 Identities = 43/169 (25%), Positives = 73/169 (43%), Gaps = 41/169 (24%) Frame = +2 Query: 5 GIPLESGKVLSALATFRVLQEPIYNLPDTISMMIQTKVSLDRIASFLCLEELPTDA---- 172 G L+ + ++L+ F +L P++ L + ++ +S+ ++ FL +E+ D+ Sbjct: 563 GNNLQPAEAFASLSLFHILVTPLFLLSTVVRFAVKAIISVQKLNEFLLSDEIGDDSWRTG 622 Query: 173 ------------------------------------VDRL-PSGSSNVAIEVSNGCFSWD 241 RL P + ++AI+V+NGCFSW Sbjct: 623 EASLPFESCKKHTGVQPKTINRKQPGRYHLDSYEQSTRRLRPMETEDIAIKVTNGCFSWG 682 Query: 242 GSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEV 388 TL +++ + G + G VG GKSSLL ILGE+ L G+V Sbjct: 683 SGAA--TLSNIDIRIPTGQLTMIVGQVGCGKSSLLLAILGEMQTLDGKV 729 Score = 36.6 bits (83), Expect = 0.030 Identities = 33/127 (25%), Positives = 53/127 (41%), Gaps = 7/127 (5%) Frame = +2 Query: 29 VLSALATFRVLQEPIYNLPDTISMMIQTKVSLDRIASFLCLEEL-------PTDAVDRLP 187 +L AL L + NL D M K ++ SFL +E P+ + P Sbjct: 1252 LLYALTITNYLNWVVRNLADLEVQMGAVK----KVNSFLTMESENYEGTMDPSQVPEHWP 1307 Query: 188 SGSSNVAIEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEV 367 I++ + C ++ + + P LK + + G +V +CG GSGKSSL V Sbjct: 1308 QEGE---IKIHDLCVRYENNLK-PVLKHVKAYIKPGQKVGICGRTGSGKSSLSLAFFRMV 1363 Query: 368 PKLSGEV 388 G++ Sbjct: 1364 DIFDGKI 1370
>CFTR_BOVIN (P35071) Cystic fibrosis transmembrane conductance regulator (CFTR)| (cAMP-dependent chloride channel) (ATP-binding cassette transporter sub-family C member 7) Length = 1481 Score = 61.2 bits (147), Expect = 1e-09 Identities = 39/114 (34%), Positives = 66/114 (57%), Gaps = 3/114 (2%) Frame = +2 Query: 110 TKVSLDRIASFLCLEELPTDAVDRLPSGSSNVAIEVSNGCFSWDGSPEL---PTLKDLNF 280 T V +D + +F EE + ++ ++N ++SNG S S L P LKD++F Sbjct: 390 TDVVMDNVTAFW--EEGFSKLFEKAKENNNNR--KISNGDNSLFFSNLLLGTPVLKDISF 445 Query: 281 QAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEVKTCGTMAYVSQTAWIQSG 442 + ++G +AV G+ G+GK+SLL I+GE+ G++K G +++ SQ +WI G Sbjct: 446 KIERGQLLAVAGSTGAGKTSLLLMIMGELEASEGKIKHSGRISFCSQYSWIMPG 499
>CFTR_PIG (Q6PQZ2) Cystic fibrosis transmembrane conductance regulator (CFTR)| (cAMP-dependent chloride channel) (ATP-binding cassette transporter sub-family C member 7) Length = 1482 Score = 60.8 bits (146), Expect = 1e-09 Identities = 26/62 (41%), Positives = 43/62 (69%) Frame = +2 Query: 257 PTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEVKTCGTMAYVSQTAWIQ 436 P LKD++F+ ++G +AV G+ G+GK+SLL I+GE+ G++K G +++ SQ +WI Sbjct: 439 PVLKDISFKIERGQLLAVAGSTGAGKTSLLMMIMGELEPSEGKIKHSGRISFCSQFSWIM 498 Query: 437 SG 442 G Sbjct: 499 PG 500
>CFTR_SHEEP (Q00555) Cystic fibrosis transmembrane conductance regulator (CFTR)| (cAMP-dependent chloride channel) (ATP-binding cassette transporter sub-family C member 7) Length = 1481 Score = 60.8 bits (146), Expect = 1e-09 Identities = 26/62 (41%), Positives = 43/62 (69%) Frame = +2 Query: 257 PTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEVKTCGTMAYVSQTAWIQ 436 P LKD++F+ ++G +AV G+ G+GK+SLL I+GE+ G++K G +++ SQ +WI Sbjct: 438 PVLKDISFKIERGQLLAVAGSTGAGKTSLLMMIMGELEPSEGKIKHSGRISFCSQYSWIM 497 Query: 437 SG 442 G Sbjct: 498 PG 499
>CFTR_MICMU (Q2QL83) Cystic fibrosis transmembrane conductance regulator (CFTR)| (cAMP-dependent chloride channel) (ATP-binding cassette transporter sub-family C member 7) Length = 1481 Score = 60.8 bits (146), Expect = 1e-09 Identities = 26/62 (41%), Positives = 43/62 (69%) Frame = +2 Query: 257 PTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEVKTCGTMAYVSQTAWIQ 436 P LKD++F+ ++G +AV G+ G+GK+SLL I+GE+ G++K G +++ SQ +WI Sbjct: 439 PVLKDISFKIERGQLLAVAGSTGAGKTSLLMMIMGELEPSEGKIKHSGRISFCSQFSWIM 498 Query: 437 SG 442 G Sbjct: 499 PG 500 Score = 34.3 bits (77), Expect = 0.15 Identities = 18/46 (39%), Positives = 27/46 (58%) Frame = +2 Query: 263 LKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEVKTCG 400 L++++F G RV + G GSGKS+LLS L + GE++ G Sbjct: 1228 LENISFSISPGQRVGLLGRTGSGKSTLLSAFL-RLLNTEGEIQIDG 1272
>CFTR_HORSE (Q2QLA3) Cystic fibrosis transmembrane conductance regulator (CFTR)| (cAMP-dependent chloride channel) (ATP-binding cassette transporter sub-family C member 7) Length = 1481 Score = 60.8 bits (146), Expect = 1e-09 Identities = 26/62 (41%), Positives = 43/62 (69%) Frame = +2 Query: 257 PTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEVKTCGTMAYVSQTAWIQ 436 P LKD++F+ ++G +AV G+ G+GK+SLL I+GE+ G++K G +++ SQ +WI Sbjct: 438 PVLKDISFKIERGQLLAVAGSTGAGKTSLLMMIMGELEPSEGKIKHSGRISFCSQFSWIM 497 Query: 437 SG 442 G Sbjct: 498 PG 499 Score = 34.3 bits (77), Expect = 0.15 Identities = 18/46 (39%), Positives = 27/46 (58%) Frame = +2 Query: 263 LKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEVKTCG 400 L++++F G RV + G GSGKS+LLS L + GE++ G Sbjct: 1228 LENISFSISPGQRVGLLGRTGSGKSTLLSAFL-RLLNTEGEIQIDG 1272
>CFTR_XENLA (P26363) Cystic fibrosis transmembrane conductance regulator (CFTR)| (cAMP-dependent chloride channel) (ATP-binding cassette transporter sub-family C member 7) Length = 1485 Score = 60.5 bits (145), Expect = 2e-09 Identities = 28/88 (31%), Positives = 52/88 (59%) Frame = +2 Query: 179 RLPSGSSNVAIEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCIL 358 +L N++ E + FS P L+++NF+ ++G +A+ G+ G+GK+SLL I+ Sbjct: 414 KLEVNGGNISNEDPSAFFSNFSLHVAPVLRNINFKIEKGQLLAIAGSTGAGKTSLLMMIM 473 Query: 359 GEVPKLSGEVKTCGTMAYVSQTAWIQSG 442 GE+ +G++K G +++ Q +WI G Sbjct: 474 GELEPSAGKIKHSGRISFSPQVSWIMPG 501 Score = 33.5 bits (75), Expect = 0.25 Identities = 15/32 (46%), Positives = 21/32 (65%) Frame = +2 Query: 263 LKDLNFQAQQGMRVAVCGTVGSGKSSLLSCIL 358 L++++F G RV + G GSGKS+LLS L Sbjct: 1230 LENISFSLSPGQRVGLLGRTGSGKSTLLSAFL 1261
>ABCC9_RAT (Q63563) ATP-binding cassette transporter sub-family C member 9| (Sulfonylurea receptor 2) Length = 1545 Score = 60.1 bits (144), Expect = 2e-09 Identities = 44/168 (26%), Positives = 74/168 (44%), Gaps = 40/168 (23%) Frame = +2 Query: 5 GIPLESGKVLSALATFRVLQEPIYNLPDTISMMIQTKVSLDRIASFLCLEELPTDA---- 172 G L+ + ++L+ F +L P++ L + ++ +S+ ++ FL +E+ D+ Sbjct: 560 GNNLKPAEAFASLSLFHILVTPLFLLSTVVRFAVKAIISVQKLNEFLLSDEIGEDSWRTG 619 Query: 173 -----------------------------------VDRL-PSGSSNVAIEVSNGCFSWDG 244 RL P+ + +VAI+V+NG FSW Sbjct: 620 EGTLPFESCKKHTGVQSKPINRKQPGRYHLDNYEQARRLRPAETEDVAIKVTNGYFSWGS 679 Query: 245 SPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEV 388 L TL +++ + G + G VG GKSSLL ILGE+ L G+V Sbjct: 680 G--LATLSNIDIRIPTGQLTMIVGQVGCGKSSLLLAILGEMQTLEGKV 725 Score = 36.6 bits (83), Expect = 0.030 Identities = 33/127 (25%), Positives = 53/127 (41%), Gaps = 7/127 (5%) Frame = +2 Query: 29 VLSALATFRVLQEPIYNLPDTISMMIQTKVSLDRIASFLCLEEL-------PTDAVDRLP 187 +L AL L + NL D M K ++ SFL +E P+ + P Sbjct: 1248 LLYALTITNYLNWVVRNLADLEVQMGAVK----KVNSFLTMESENYEGTMDPSQVPEHWP 1303 Query: 188 SGSSNVAIEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEV 367 I++ + C ++ + + P LK + + G +V +CG GSGKSSL V Sbjct: 1304 QEGE---IKIHDLCVRYENNLK-PVLKHVKAYIKPGQKVGICGRTGSGKSSLSLAFFRMV 1359 Query: 368 PKLSGEV 388 G++ Sbjct: 1360 DIFDGKI 1366
>CFTR_DIDMA (Q2QL74) Cystic fibrosis transmembrane conductance regulator (CFTR)| (cAMP-dependent chloride channel) (ATP-binding cassette transporter sub-family C member 7) Length = 1482 Score = 59.7 bits (143), Expect = 3e-09 Identities = 31/86 (36%), Positives = 53/86 (61%), Gaps = 4/86 (4%) Frame = +2 Query: 197 SNVAIEVSNG----CFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGE 364 +N +++SNG FS P LK+++F+ ++G +AV G+ G+GK+SLL I+GE Sbjct: 415 NNSDVKMSNGDNGLFFSNFSLLGTPVLKNISFKIEKGQLLAVAGSTGAGKTSLLMMIMGE 474 Query: 365 VPKLSGEVKTCGTMAYVSQTAWIQSG 442 + G++K G +++ SQ +WI G Sbjct: 475 LEPSEGKIKHSGRISFCSQFSWIMPG 500
>ABCC9_MOUSE (P70170) ATP-binding cassette transporter sub-family C member 9| (Sulfonylurea receptor 2) Length = 1546 Score = 59.7 bits (143), Expect = 3e-09 Identities = 43/168 (25%), Positives = 74/168 (44%), Gaps = 40/168 (23%) Frame = +2 Query: 5 GIPLESGKVLSALATFRVLQEPIYNLPDTISMMIQTKVSLDRIASFLCLEELPTDA---- 172 G L+ + ++L+ F +L P++ L + ++ +S+ ++ FL +E+ D+ Sbjct: 561 GNNLKPAEAFASLSLFHILVTPLFLLSTVVRFAVKAIISVQKLNEFLLSDEIGEDSWRAG 620 Query: 173 -----------------------------------VDRL-PSGSSNVAIEVSNGCFSWDG 244 RL P+ + ++AI+V+NG FSW Sbjct: 621 EGTLPFESCKKHTGVQSKPINRKQPGRYHLDSYEQARRLRPAETEDIAIKVTNGYFSWGS 680 Query: 245 SPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEV 388 L TL +++ + G + G VG GKSSLL ILGE+ L G+V Sbjct: 681 G--LATLSNIDIRIPTGQLTMIVGQVGCGKSSLLLAILGEMQTLEGKV 726 Score = 36.6 bits (83), Expect = 0.030 Identities = 33/127 (25%), Positives = 53/127 (41%), Gaps = 7/127 (5%) Frame = +2 Query: 29 VLSALATFRVLQEPIYNLPDTISMMIQTKVSLDRIASFLCLEEL-------PTDAVDRLP 187 +L AL L + NL D M K ++ SFL +E P+ + P Sbjct: 1249 LLYALTITNYLNWVVRNLADLEVQMGAVK----KVNSFLTMESENYEGTMDPSQVPEHWP 1304 Query: 188 SGSSNVAIEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEV 367 I++ + C ++ + + P LK + + G +V +CG GSGKSSL V Sbjct: 1305 QEGE---IKIHDLCVRYENNLK-PVLKHVKAYIKPGQKVGICGRTGSGKSSLSLAFFRMV 1360 Query: 368 PKLSGEV 388 G++ Sbjct: 1361 DIFDGKI 1367
>CFTR_SQUAC (P26362) Cystic fibrosis transmembrane conductance regulator (CFTR)| (cAMP-dependent chloride channel) (ATP-binding cassette transporter sub-family C member 7) Length = 1492 Score = 59.3 bits (142), Expect = 4e-09 Identities = 26/62 (41%), Positives = 41/62 (66%) Frame = +2 Query: 257 PTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEVKTCGTMAYVSQTAWIQ 436 P LK+++F+ ++G +A+ G+ GSGKSSLL I+GE+ G++K G ++Y Q WI Sbjct: 440 PVLKNISFKLEKGELLAIAGSTGSGKSSLLMMIMGELEPSDGKIKHSGRISYSPQVPWIM 499 Query: 437 SG 442 G Sbjct: 500 PG 501 Score = 37.0 bits (84), Expect = 0.023 Identities = 19/46 (41%), Positives = 28/46 (60%) Frame = +2 Query: 263 LKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEVKTCG 400 L+DL+F G RV + G G+GKS+LLS +L + GE++ G Sbjct: 1237 LQDLSFSVNAGQRVGLLGRTGAGKSTLLSALL-RLLSTEGEIQIDG 1281
>CFTR_MOUSE (P26361) Cystic fibrosis transmembrane conductance regulator (CFTR)| (cAMP-dependent chloride channel) (ATP-binding cassette transporter sub-family C member 7) Length = 1476 Score = 57.4 bits (137), Expect = 2e-08 Identities = 26/62 (41%), Positives = 40/62 (64%) Frame = +2 Query: 257 PTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEVKTCGTMAYVSQTAWIQ 436 P LK++N ++G +A+ G+ GSGK+SLL ILGE+ G +K G +++ SQ +WI Sbjct: 439 PVLKNINLNIEKGEMLAITGSTGSGKTSLLMLILGELEASEGIIKHSGRVSFCSQFSWIM 498 Query: 437 SG 442 G Sbjct: 499 PG 500 Score = 36.6 bits (83), Expect = 0.030 Identities = 35/142 (24%), Positives = 60/142 (42%), Gaps = 21/142 (14%) Frame = +2 Query: 38 ALATFRVLQEPIYNLPDTISMMIQTKVSLDRIASFLCL---EELPTDAVDRLPSGSSNVA 208 A+ LQ + + DT S+M S+ R+ F+ + E + T + LP S+ Sbjct: 1131 AMNIMSTLQWAVNSSIDTDSLMR----SVSRVFKFIDIQTEESMYTQIIKELPREGSSDV 1186 Query: 209 IEVSNGCFS----WDGSPEL--------------PTLKDLNFQAQQGMRVAVCGTVGSGK 334 + + N W E+ L++++F G RV + G GSGK Sbjct: 1187 LVIKNEHVKKSDIWPSGGEMVVKDLTVKYMDDGNAVLENISFSISPGQRVGLLGRTGSGK 1246 Query: 335 SSLLSCILGEVPKLSGEVKTCG 400 S+LLS L + + G+++ G Sbjct: 1247 STLLSAFL-RMLNIKGDIEIDG 1267
>ABCC9_HUMAN (O60706) ATP-binding cassette transporter sub-family C member 9| (Sulfonylurea receptor 2) Length = 1549 Score = 56.2 bits (134), Expect = 4e-08 Identities = 43/169 (25%), Positives = 73/169 (43%), Gaps = 41/169 (24%) Frame = +2 Query: 5 GIPLESGKVLSALATFRVLQEPIYNLPDTISMMIQTKVSLDRIASFLCLEELPTDA---- 172 G L+ + ++L+ F +L P+ L + ++ +S+ ++ FL +E+ D+ Sbjct: 563 GNNLKPAEAFASLSLFHILVTPLSLLFTVVRFAVKAIISVQKLNEFLLSDEIGDDSWRTG 622 Query: 173 ------------------------------------VDRL-PSGSSNVAIEVSNGCFSWD 241 RL P+ + ++AI+V+NG FSW Sbjct: 623 ESSLPFESCKKHTGVQPKTINRKQPGRYHLDSYEQSTRRLRPAETEDIAIKVTNGYFSWG 682 Query: 242 GSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEV 388 L TL +++ + G + G VG GKSSLL ILGE+ L G+V Sbjct: 683 SG--LATLSNIDIRIPTGQLTMIVGQVGCGKSSLLLAILGEMQTLEGKV 729 Score = 36.6 bits (83), Expect = 0.030 Identities = 33/127 (25%), Positives = 53/127 (41%), Gaps = 7/127 (5%) Frame = +2 Query: 29 VLSALATFRVLQEPIYNLPDTISMMIQTKVSLDRIASFLCLEEL-------PTDAVDRLP 187 +L AL L + NL D M K ++ SFL +E P+ + P Sbjct: 1252 LLYALTITNYLNWVVRNLADLEVQMGAVK----KVNSFLTMESENYEGTMDPSQVPEHWP 1307 Query: 188 SGSSNVAIEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEV 367 I++ + C ++ + + P LK + + G +V +CG GSGKSSL V Sbjct: 1308 QEGE---IKIHDLCVRYENNLK-PVLKHVKAYIKPGQKVGICGRTGSGKSSLSLAFFRMV 1363 Query: 368 PKLSGEV 388 G++ Sbjct: 1364 DIFDGKI 1370
>ABCC8_CRICR (Q09427) ATP-binding cassette transporter sub-family C member 8| (Sulfonylurea receptor 1) Length = 1581 Score = 53.1 bits (126), Expect = 3e-07 Identities = 44/211 (20%), Positives = 81/211 (38%), Gaps = 71/211 (33%) Frame = +2 Query: 14 LESGKVLSALATFRVLQEPIYNLPDTISMMIQTKVSLDRIASFLCLEEL----------- 160 L ++L+ F +L P++ L + ++ VS+ +++ FL E+ Sbjct: 570 LSPSVAFASLSLFHILVTPLFLLSSVVRSTVKALVSVQKLSEFLSSAEIREEQCAPREPA 629 Query: 161 -----------PTDAVDR---------------------LPSGSSNVAIEVSNGCFSWDG 244 P V+R + + N +++ G F+W Sbjct: 630 PQGQAGKYQAVPLKVVNRKRPAREEVRDLLGPLQRLAPSMDGDADNFCVQIIGGFFTW-- 687 Query: 245 SPE-LPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSG------------- 382 +P+ +PTL ++ + +G + G VG GKSSLL LGE+ K+SG Sbjct: 688 TPDGIPTLSNITIRIPRGQLTMIVGQVGCGKSSLLLATLGEMQKVSGAVFWNSNLPDSEG 747 Query: 383 --------------EVKTCGTMAYVSQTAWI 433 ++++ G +AY SQ W+ Sbjct: 748 EDPSSPERETAAGSDIRSRGPVAYASQKPWL 778 Score = 36.2 bits (82), Expect = 0.039 Identities = 19/60 (31%), Positives = 28/60 (46%) Frame = +2 Query: 209 IEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEV 388 I++ N +D S + P LK +N G ++ +CG GSGKSS V G + Sbjct: 1344 IQIQNLSVRYDSSLK-PVLKHVNTLISPGQKIGICGRTGSGKSSFSLAFFRMVDMFEGRI 1402
>ABCC8_HUMAN (Q09428) ATP-binding cassette transporter sub-family C member 8| (Sulfonylurea receptor 1) Length = 1580 Score = 52.8 bits (125), Expect = 4e-07 Identities = 40/162 (24%), Positives = 71/162 (43%), Gaps = 44/162 (27%) Frame = +2 Query: 35 SALATFRVLQEPIYNLPDTISMMIQTKVSLDRIASFLCLEEL------------------ 160 ++L+ F +L P++ L + ++ VS+ +++ FL E+ Sbjct: 577 ASLSLFHILVTPLFLLSSVVRSTVKALVSVQKLSEFLSSAEIREEQCAPHEPTPQGPASK 636 Query: 161 ----PTDAVDR------------------LPSG---SSNVAIEVSNGCFSWDGSPE-LPT 262 P V+R +PS + N +++ G F+W +P+ +PT Sbjct: 637 YQAVPLRVVNRKRPAREDCRGLTGPLQSLVPSADGDADNCCVQIMGGYFTW--TPDGIPT 694 Query: 263 LKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEV 388 L ++ + +G + G VG GKSSLL LGE+ K+SG V Sbjct: 695 LSNITIRIPRGQLTMIVGQVGCGKSSLLLAALGEMQKVSGAV 736 Score = 36.2 bits (82), Expect = 0.039 Identities = 19/60 (31%), Positives = 28/60 (46%) Frame = +2 Query: 209 IEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEV 388 I++ N +D S + P LK +N G ++ +CG GSGKSS V G + Sbjct: 1343 IQIQNLSVRYDSSLK-PVLKHVNALISPGQKIGICGRTGSGKSSFSLAFFRMVDTFEGHI 1401
>EF3_ASHGO (Q75EV6) Elongation factor 3 (EF-3)| Length = 1044 Score = 52.0 bits (123), Expect = 7e-07 Identities = 30/77 (38%), Positives = 48/77 (62%), Gaps = 3/77 (3%) Frame = +2 Query: 209 IEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEV 388 ++VSN F + G+ + P + D+NFQ R+AV G G+GKS+L++ + GE+ +GEV Sbjct: 667 VKVSNMSFQYPGTSK-PQIADINFQCSLSSRIAVIGPNGAGKSTLINVLTGELLPTTGEV 725 Query: 389 KT---CGTMAYVSQTAW 430 T C +AY+ Q A+ Sbjct: 726 YTHENC-RIAYIKQHAF 741
>EF3_CANGA (O93796) Elongation factor 3 (EF-3)| Length = 1045 Score = 51.6 bits (122), Expect = 9e-07 Identities = 30/77 (38%), Positives = 48/77 (62%), Gaps = 3/77 (3%) Frame = +2 Query: 209 IEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEV 388 ++VSN F + G+ + P + D++FQ R+AV G G+GKS+L++ + GE+ SGEV Sbjct: 667 VKVSNMTFQYPGTSK-PQISDISFQCSLSSRIAVIGPNGAGKSTLINVLTGELLPTSGEV 725 Query: 389 KT---CGTMAYVSQTAW 430 T C +AY+ Q A+ Sbjct: 726 YTHENC-RIAYIKQHAF 741 Score = 28.9 bits (63), Expect = 6.2 Identities = 21/74 (28%), Positives = 36/74 (48%), Gaps = 5/74 (6%) Frame = +2 Query: 149 LEELPTDAVDRLPSGSS-----NVAIEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVC 313 L+E AVD +P G + + ++ N FS ++ L + ++G R +C Sbjct: 404 LDEFRKRAVDNIPVGPNFDDEEDEGEDLCNCEFSLAYGAKI-LLNKTQLRLKRGRRYGLC 462 Query: 314 GTVGSGKSSLLSCI 355 G G+GKS+L+ I Sbjct: 463 GPNGAGKSTLMRAI 476
>ABCC8_RAT (Q09429) ATP-binding cassette transporter sub-family C member 8| (Sulfonylurea receptor 1) Length = 1581 Score = 51.6 bits (122), Expect = 9e-07 Identities = 40/162 (24%), Positives = 70/162 (43%), Gaps = 44/162 (27%) Frame = +2 Query: 35 SALATFRVLQEPIYNLPDTISMMIQTKVSLDRIASFLCLEEL------------------ 160 ++L+ F +L P++ L + ++ VS+ +++ FL E+ Sbjct: 577 ASLSLFHILVTPLFLLSSVVRSTVKALVSVQKLSEFLSSAEIREEQCAPREPAPQGQAGK 636 Query: 161 ----PTDAVDR------------------LPS---GSSNVAIEVSNGCFSWDGSPE-LPT 262 P V+R PS + N +++ G F+W +P+ +PT Sbjct: 637 YQAVPLKVVNRKRPAREEVRDLLGPLQRLTPSTDGDADNFCVQIIGGFFTW--TPDGIPT 694 Query: 263 LKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEV 388 L ++ + +G + G VG GKSSLL LGE+ K+SG V Sbjct: 695 LSNITIRIPRGQLTMIVGQVGCGKSSLLLATLGEMQKVSGAV 736 Score = 36.2 bits (82), Expect = 0.039 Identities = 19/60 (31%), Positives = 28/60 (46%) Frame = +2 Query: 209 IEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEV 388 I++ N +D S + P LK +N G ++ +CG GSGKSS V G + Sbjct: 1344 IQIQNLSVRYDSSLK-PVLKHVNALISPGQKIGICGRTGSGKSSFSLAFFRMVDMFEGRI 1402
>YOR1_YEAST (P53049) Oligomycin resistance ATP-dependent permease YOR1| Length = 1477 Score = 51.2 bits (121), Expect = 1e-06 Identities = 31/90 (34%), Positives = 47/90 (52%), Gaps = 5/90 (5%) Frame = +2 Query: 185 PSGSSNVAIEVSNGCFSWDGSPELPT-----LKDLNFQAQQGMRVAVCGTVGSGKSSLLS 349 PS S+N A + N DG +L KDLNF ++G + + G +G+GKSSLL+ Sbjct: 573 PSASTNKAKRLDNMLKDRDGPEDLEKTSFRGFKDLNFDIKKGEFIMITGPIGTGKSSLLN 632 Query: 350 CILGEVPKLSGEVKTCGTMAYVSQTAWIQS 439 + G + K G+V+ G + WIQ+ Sbjct: 633 AMAGSMRKTDGKVEVNGDLLMCGY-PWIQN 661 Score = 38.9 bits (89), Expect = 0.006 Identities = 33/118 (27%), Positives = 57/118 (48%), Gaps = 14/118 (11%) Frame = +2 Query: 44 ATFRVLQEPIYNLPDTISMMIQTKV-------SLDRIASFLCLEELPTDAVDRLP----- 187 A+ VL + LP ++ +++ S +R+ ++ ELP +A R P Sbjct: 1147 ASVGVLLTYVLQLPGLLNTILRAMTQTENDMNSAERLVTYAT--ELPLEASYRKPEMTPP 1204 Query: 188 -SGSSNVAIEVSNGCFSWDGSPELP-TLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCI 355 S S I N F++ P LP LK+LN + G ++ +CG G+GKS+++S + Sbjct: 1205 ESWPSMGEIIFENVDFAY--RPGLPIVLKNLNLNIKSGEKIGICGRTGAGKSTIMSAL 1260
>EF3A_YEAST (P16521) Elongation factor 3A (EF-3A) (EF-3) (Translation| elongation factor 3A) (Eukaryotic elongation factor 3) (eEF3) (Yeast elongation factor 3) Length = 1043 Score = 50.8 bits (120), Expect = 2e-06 Identities = 30/77 (38%), Positives = 48/77 (62%), Gaps = 3/77 (3%) Frame = +2 Query: 209 IEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEV 388 ++V+N F + G+ + P + D+NFQ R+AV G G+GKS+L++ + GE+ SGEV Sbjct: 666 VKVTNMEFQYPGTSK-PQITDINFQCSLSSRIAVIGPNGAGKSTLINVLTGELLPTSGEV 724 Query: 389 KT---CGTMAYVSQTAW 430 T C +AY+ Q A+ Sbjct: 725 YTHENC-RIAYIKQHAF 740
>Y288_THEMA (Q9WYC4) Hypothetical ABC transporter ATP-binding protein TM0288| Length = 598 Score = 50.8 bits (120), Expect = 2e-06 Identities = 33/112 (29%), Positives = 55/112 (49%) Frame = +2 Query: 23 GKVLSALATFRVLQEPIYNLPDTISMMIQTKVSLDRIASFLCLEELPTDAVDRLPSGSSN 202 G + + + R P+ L + +M+ S +RI L LEE D D + Sbjct: 294 GTIATFIGYSRQFTRPLNELSNQFNMIQMALASAERIFEILDLEEEKDDP-DAVELREVR 352 Query: 203 VAIEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCIL 358 IE N FS+D + P LKD+ F + G +VA+ G GSGK+++++ ++ Sbjct: 353 GEIEFKNVWFSYD--KKKPVLKDITFHIKPGQKVALVGPTGSGKTTIVNLLM 402
>EF3B_YEAST (P53978) Elongation factor 3B (EF-3B) (Translation elongation| factor 3B) (Homolog of EF-3) Length = 1043 Score = 50.4 bits (119), Expect = 2e-06 Identities = 30/77 (38%), Positives = 47/77 (61%), Gaps = 3/77 (3%) Frame = +2 Query: 209 IEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEV 388 ++VSN F + G+ + P + D+ FQ R+AV G G+GKS+L++ + GE+ SGEV Sbjct: 666 VKVSNMTFQYPGTTK-PQVSDVTFQCSLSSRIAVIGPNGAGKSTLINVLTGELLPTSGEV 724 Query: 389 KT---CGTMAYVSQTAW 430 T C +AY+ Q A+ Sbjct: 725 YTHENC-RIAYIKQHAF 740
>EF3_CANAL (P25997) Elongation factor 3 (EF-3)| Length = 1049 Score = 50.1 bits (118), Expect = 3e-06 Identities = 28/76 (36%), Positives = 47/76 (61%), Gaps = 2/76 (2%) Frame = +2 Query: 209 IEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGE- 385 ++VSN F + G+ + P ++D+NFQ R+AV G G+GKS+L++ + GE+ +GE Sbjct: 671 VKVSNMSFQYPGTSK-PQIQDINFQCSLSSRIAVIGPNGAGKSTLINVLTGELLPTTGEF 729 Query: 386 -VKTCGTMAYVSQTAW 430 V +AY+ Q A+ Sbjct: 730 YVHENCRIAYIKQHAF 745
>CBIO_VIBPA (Q87G35) Putative cobalt import ATP-binding protein cbiO| Length = 579 Score = 48.5 bits (114), Expect = 8e-06 Identities = 28/74 (37%), Positives = 45/74 (60%), Gaps = 1/74 (1%) Frame = +2 Query: 203 VAIEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVP-KLS 379 + IE SN F ++ S + PTLK++N + ++G ++ + G GSGKS+L C+ G +P + Sbjct: 1 MTIEFSNFSFRYE-SLDKPTLKNINLRIEKGEKIVIIGPSGSGKSTLGQCLNGLIPHAIK 59 Query: 380 GEVKTCGTMAYVSQ 421 GE T GT+ Q Sbjct: 60 GE--TSGTLTIYGQ 71 Score = 43.5 bits (101), Expect = 2e-04 Identities = 38/148 (25%), Positives = 69/148 (46%), Gaps = 17/148 (11%) Frame = +2 Query: 8 IPLESGKVLSALATFRVLQEPI---YNL--PDTISMMIQTKVSLDRIASFLCLEELPTD- 169 I +ESG++++ +L P+ Y + P IS + + +++ A L LP + Sbjct: 215 ILMESGEIIADTTPDEILASPLLEDYGIREPLYISALKEAGCAIEGDAKPSSLTTLPLEQ 274 Query: 170 -----------AVDRLPSGSSNVAIEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCG 316 + + P + +EV +S+DG E L+D++F ++G V+V G Sbjct: 275 YKPTVQAWFDGSTAQPPKTPAETLLEVRGLTYSYDG--EKNALEDVSFDIKRGEFVSVLG 332 Query: 317 TVGSGKSSLLSCILGEVPKLSGEVKTCG 400 GSGKS++ I+G + SG + G Sbjct: 333 KNGSGKSTITKLIMGVIEADSGSMSMNG 360
>EF3_SCHPO (O94489) Elongation factor 3 (EF-3)| Length = 1047 Score = 48.1 bits (113), Expect = 1e-05 Identities = 29/81 (35%), Positives = 47/81 (58%), Gaps = 3/81 (3%) Frame = +2 Query: 209 IEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEV 388 I+V + F + G+ + P L D++FQ R+AV G G+GKS+L+ + GE+ GE+ Sbjct: 673 IKVQHMSFQYPGTSK-PQLNDISFQVSLSSRIAVIGPNGAGKSTLIKVLTGELLPTVGEI 731 Query: 389 ---KTCGTMAYVSQTAWIQSG 442 + C +AYV+Q A+ G Sbjct: 732 YQHENC-RIAYVAQAAFTHLG 751 Score = 33.9 bits (76), Expect = 0.19 Identities = 25/88 (28%), Positives = 46/88 (52%), Gaps = 6/88 (6%) Frame = +2 Query: 149 LEELPTDAVDRLPSGSSNVAIE-----VSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVC 313 +E+L T ++ ++P G+S+ E + N FS ++ L + ++G R +C Sbjct: 408 VEQLRTRSIAKIPGGASHAEEEEEGEDLCNCEFSLAYGAKI-LLNRTRLRLKRGRRYGLC 466 Query: 314 GTVGSGKSSLLSCIL-GEVPKLSGEVKT 394 G GSGKS+L+ I+ G+V ++T Sbjct: 467 GPNGSGKSTLMRAIVNGQVEGFPTHLRT 494
>CBIO1_ENTFA (Q839D5) Cobalt import ATP-binding protein cbiO 1| Length = 279 Score = 46.6 bits (109), Expect = 3e-05 Identities = 26/64 (40%), Positives = 37/64 (57%) Frame = +2 Query: 209 IEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEV 388 IE++N F++ P LKD++F QQG VA+ G GSGKS+L I G + +G + Sbjct: 5 IELNNIQFNYQPEDASPALKDVSFSIQQGEWVAIIGHNGSGKSTLAKTINGLLLPAAGTI 64 Query: 389 KTCG 400 K G Sbjct: 65 KVGG 68
>MDR_LEITA (P21441) Multidrug resistance protein (EC 3.6.3.44)| (P-glycoprotein) Length = 1548 Score = 46.2 bits (108), Expect = 4e-05 Identities = 23/59 (38%), Positives = 36/59 (61%) Frame = +2 Query: 263 LKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEVKTCGTMAYVSQTAWIQS 439 L++++ +G V G+ GSGKS+LL ++GE SGE+ ++AYV Q AWI + Sbjct: 650 LRNVSLTIPKGKLTMVIGSTGSGKSTLLGALMGEYSVESGELWAERSIAYVPQQAWIMN 708 Score = 28.5 bits (62), Expect = 8.1 Identities = 15/46 (32%), Positives = 23/46 (50%) Frame = +2 Query: 263 LKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEVKTCG 400 L+ ++FQ +V + G GSGKS+LL + V G + G Sbjct: 1303 LRGVSFQIAPREKVGIVGRTGSGKSTLLLTFMRMVEVCGGVIHVNG 1348
>Y015_MYCGE (P47261) Hypothetical ABC transporter ATP-binding protein MG015| Length = 589 Score = 46.2 bits (108), Expect = 4e-05 Identities = 34/124 (27%), Positives = 64/124 (51%), Gaps = 4/124 (3%) Frame = +2 Query: 29 VLSALATFRVLQ---EPIYNLPDTISMMIQTKVSLDRIASFLCLE-ELPTDAVDRLPSGS 196 +LS +A+ R + + I+ L + + + + VS +R+ L L E T +D+LP Sbjct: 293 MLSYIASLRQITLALDQIFTLWNLVQLGV---VSAERVFKVLDLNVEKDTATIDKLPDIK 349 Query: 197 SNVAIEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKL 376 N+ E N F ++ + PTL +NF + G VA+ G G+GKS++++ ++ Sbjct: 350 GNIRFE--NVAFGYN--KDKPTLTGINFSVKHGDVVAIVGPTGAGKSTIINLLMKFYKPF 405 Query: 377 SGEV 388 G++ Sbjct: 406 EGKI 409
>CBIO_VIBVY (Q7MFH3) Putative cobalt import ATP-binding protein cbiO| Length = 574 Score = 46.2 bits (108), Expect = 4e-05 Identities = 24/63 (38%), Positives = 41/63 (65%), Gaps = 1/63 (1%) Frame = +2 Query: 203 VAIEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVP-KLS 379 + IE SN F ++ S + PTL+++N + ++G ++ + G GSGKS+L C+ G +P + Sbjct: 1 MTIEFSNFSFRYE-SLDKPTLRNINLRIEKGEKIVIIGPSGSGKSTLGQCLNGLIPHAIK 59 Query: 380 GEV 388 GEV Sbjct: 60 GEV 62 Score = 38.5 bits (88), Expect = 0.008 Identities = 22/68 (32%), Positives = 37/68 (54%) Frame = +2 Query: 197 SNVAIEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKL 376 S ++V N +S+DG E L+ ++F Q+G V++ G GSGKS++ I+G + Sbjct: 295 SETLLDVRNLTYSYDG--EKNALEGVSFNVQRGEFVSILGKNGSGKSTITKLIMGVIEPD 352 Query: 377 SGEVKTCG 400 G + G Sbjct: 353 DGTMHLNG 360
>CBIO_VIBVU (Q8D3Z9) Cobalt import ATP-binding protein cbiO| Length = 574 Score = 46.2 bits (108), Expect = 4e-05 Identities = 24/63 (38%), Positives = 41/63 (65%), Gaps = 1/63 (1%) Frame = +2 Query: 203 VAIEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVP-KLS 379 + IE SN F ++ S + PTL+++N + ++G ++ + G GSGKS+L C+ G +P + Sbjct: 1 MTIEFSNFSFRYE-SLDKPTLRNINLRIEKGEKIVIIGPSGSGKSTLGQCLNGLIPHAIK 59 Query: 380 GEV 388 GEV Sbjct: 60 GEV 62 Score = 38.9 bits (89), Expect = 0.006 Identities = 21/64 (32%), Positives = 36/64 (56%) Frame = +2 Query: 197 SNVAIEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKL 376 S ++V N +S+DG E L+ ++F Q+G V++ G GSGKS++ I+G + Sbjct: 295 SETLLDVRNLTYSYDG--EKNALEGVSFNVQRGEFVSILGKNGSGKSTITKLIMGVIEPD 352 Query: 377 SGEV 388 G + Sbjct: 353 DGAI 356
>EF3_PNECA (P29551) Elongation factor 3 (EF-3)| Length = 1042 Score = 45.8 bits (107), Expect = 5e-05 Identities = 26/73 (35%), Positives = 43/73 (58%), Gaps = 2/73 (2%) Frame = +2 Query: 230 FSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEVKTCGTM- 406 F ++G+ E P +K+++ Q R+AV G G+GKS+L+ + GE+ GEV + Sbjct: 675 FQYEGTSE-PQIKNVSLQVSLSSRIAVIGPNGAGKSTLIKVLCGELIPQKGEVWCHPNLR 733 Query: 407 -AYVSQTAWIQSG 442 AYV+Q A++ G Sbjct: 734 IAYVAQAAFVHLG 746 Score = 30.4 bits (67), Expect = 2.1 Identities = 17/45 (37%), Positives = 25/45 (55%), Gaps = 1/45 (2%) Frame = +2 Query: 263 LKDLNFQAQQGMRVAVCGTVGSGKSSLLSCIL-GEVPKLSGEVKT 394 L + ++G R +CG GSGKS+LL I G++ E+KT Sbjct: 445 LNRTSLNLKRGYRYGLCGPNGSGKSTLLRSIFNGQLEGFPTELKT 489
>MDLA_ECOLI (P77265) Multidrug resistance-like ATP-binding protein mdlA (EC| 3.6.3.44) Length = 590 Score = 45.8 bits (107), Expect = 5e-05 Identities = 28/126 (22%), Positives = 58/126 (46%) Frame = +2 Query: 14 LESGKVLSALATFRVLQEPIYNLPDTISMMIQTKVSLDRIASFLCLEELPTDAVDRLPSG 193 L G++ S + ++ P+ L +++ + + RI + L + D + +P G Sbjct: 272 LTLGQLTSFMMYLGLMIWPMLALAWMFNIVERGSAAYSRIRAMLAEAPVVNDGSEPVPEG 331 Query: 194 SSNVAIEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPK 373 + + + + + P L+++NF + G + +CG GSGKS+LLS I Sbjct: 332 RGELDVNIHQFTYP---QTDHPALENVNFALKPGQMLGICGPTGSGKSTLLSLIQRHFDV 388 Query: 374 LSGEVK 391 G+++ Sbjct: 389 SEGDIR 394
>MNTB_BACSU (O34338) Manganese transport system ATP-binding protein mntB| Length = 250 Score = 45.4 bits (106), Expect = 6e-05 Identities = 19/48 (39%), Positives = 31/48 (64%) Frame = +2 Query: 257 PTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEVKTCG 400 P L+D++ Q +G + + G G+GKS+L+ ILG VP+ SG++ G Sbjct: 17 PVLQDISLQVPEGKLIGIIGPNGAGKSTLIKTILGLVPRASGDISIYG 64
>MDLB_ECOLI (P0AAG5) Multidrug resistance-like ATP-binding protein mdlB (EC| 3.6.3.44) Length = 593 Score = 45.1 bits (105), Expect = 8e-05 Identities = 38/130 (29%), Positives = 62/130 (47%), Gaps = 1/130 (0%) Frame = +2 Query: 14 LESGKVLSALATFRVLQEPIYNLPDTISMMIQTKVSLDRIASFLCLEELPTDAVDR-LPS 190 +E G + + ++ L EP+ L +M+ Q V+ +R+ + DR L S Sbjct: 279 IEVGVLYAFISYLGRLNEPLIELTTQQAMLQQAVVAGERVFELMDGPRQQYGNDDRPLQS 338 Query: 191 GSSNVAIEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVP 370 G+ IEV N F++ + LK++N VA+ G GSGKS+L S ++G P Sbjct: 339 GT----IEVDNVSFAY--RDDNLVLKNINLSVPSRNFVALVGHTGSGKSTLASLLMGYYP 392 Query: 371 KLSGEVKTCG 400 GE++ G Sbjct: 393 LTEGEIRLDG 402
>MDLB_ECOL6 (P0AAG6) Multidrug resistance-like ATP-binding protein mdlB (EC| 3.6.3.44) Length = 593 Score = 45.1 bits (105), Expect = 8e-05 Identities = 38/130 (29%), Positives = 62/130 (47%), Gaps = 1/130 (0%) Frame = +2 Query: 14 LESGKVLSALATFRVLQEPIYNLPDTISMMIQTKVSLDRIASFLCLEELPTDAVDR-LPS 190 +E G + + ++ L EP+ L +M+ Q V+ +R+ + DR L S Sbjct: 279 IEVGVLYAFISYLGRLNEPLIELTTQQAMLQQAVVAGERVFELMDGPRQQYGNDDRPLQS 338 Query: 191 GSSNVAIEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVP 370 G+ IEV N F++ + LK++N VA+ G GSGKS+L S ++G P Sbjct: 339 GT----IEVDNVSFAY--RDDNLVLKNINLSVPSRNFVALVGHTGSGKSTLASLLMGYYP 392 Query: 371 KLSGEVKTCG 400 GE++ G Sbjct: 393 LTEGEIRLDG 402
>MDLB_ECO57 (P0AAG7) Multidrug resistance-like ATP-binding protein mdlB (EC| 3.6.3.44) Length = 593 Score = 45.1 bits (105), Expect = 8e-05 Identities = 38/130 (29%), Positives = 62/130 (47%), Gaps = 1/130 (0%) Frame = +2 Query: 14 LESGKVLSALATFRVLQEPIYNLPDTISMMIQTKVSLDRIASFLCLEELPTDAVDR-LPS 190 +E G + + ++ L EP+ L +M+ Q V+ +R+ + DR L S Sbjct: 279 IEVGVLYAFISYLGRLNEPLIELTTQQAMLQQAVVAGERVFELMDGPRQQYGNDDRPLQS 338 Query: 191 GSSNVAIEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVP 370 G+ IEV N F++ + LK++N VA+ G GSGKS+L S ++G P Sbjct: 339 GT----IEVDNVSFAY--RDDNLVLKNINLSVPSRNFVALVGHTGSGKSTLASLLMGYYP 392 Query: 371 KLSGEVKTCG 400 GE++ G Sbjct: 393 LTEGEIRLDG 402
>CCMA_WOLPM (Q73HX8) Cytochrome c biogenesis ATP-binding export protein ccmA| (EC 3.6.3.41) (Heme exporter protein A) Length = 207 Score = 44.7 bits (104), Expect = 1e-04 Identities = 20/58 (34%), Positives = 36/58 (62%) Frame = +2 Query: 266 KDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEVKTCGTMAYVSQTAWIQS 439 K+L+F+A+ ++ + G GSGK+SL+ + G +P +SG ++ CG Y ++I S Sbjct: 18 KNLSFKAELKSKILITGPNGSGKTSLIRSLSGLLPPVSGNIRHCGKDIYDDPKSYISS 75
>EXP8_STRPN (P35598) Putative ABC transporter ATP-binding protein exp8| (Exported protein 8) Length = 583 Score = 44.3 bits (103), Expect = 1e-04 Identities = 33/130 (25%), Positives = 59/130 (45%), Gaps = 3/130 (2%) Frame = +2 Query: 8 IPLESGKVLSALATFRVLQEPIYNLPDTISMMIQTKVSLDRIASFL---CLEELPTDAVD 178 I + G + + + L +P+ + S + VS R+ + + E L + Sbjct: 275 IGITVGTMYAFIQYINRLFDPLIEVTQNFSTLQTAMVSAGRVFALIDERTYEPLQENGQA 334 Query: 179 RLPSGSSNVAIEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCIL 358 ++ G+ I + CFS+DG P L D++F +G +A G GSGKSS+++ ++ Sbjct: 335 KVQEGN----IRFEHVCFSYDGKH--PILDDISFSVNKGETIAFVGHTGSGKSSIINVLM 388 Query: 359 GEVPKLSGEV 388 SG V Sbjct: 389 RFYEFQSGRV 398
>CBIO3_LACJO (Q74I62) Putative cobalt import ATP-binding protein cbiO 3| Length = 573 Score = 44.3 bits (103), Expect = 1e-04 Identities = 23/62 (37%), Positives = 38/62 (61%), Gaps = 1/62 (1%) Frame = +2 Query: 209 IEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKL-SGE 385 IE + F ++ E PTLK++N + +G ++ + G GSGKS++ C+ G +P + GE Sbjct: 6 IEFKDFSFKYNSQAE-PTLKNINLKINKGEKILLAGPSGSGKSTIGRCLNGLIPNIDQGE 64 Query: 386 VK 391 VK Sbjct: 65 VK 66 Score = 30.0 bits (66), Expect = 2.8 Identities = 26/110 (23%), Positives = 51/110 (46%) Frame = +2 Query: 32 LSALATFRVLQEPIYNLPDTISMMIQTKVSLDRIASFLCLEELPTDAVDRLPSGSSNVAI 211 L AL V I + ++ + K+S D++A++ ++ VD LP + Sbjct: 251 LKALTAADVNLSSIKEVDQISTLPVSEKIS-DKLAAWTKQAKITKKEVDNLP------LL 303 Query: 212 EVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILG 361 ++ + + + P LKD++ QG +++ G G+GK++L I G Sbjct: 304 KLDHVGHQYSKNQPYP-LKDVSTTINQGDFISIVGQNGAGKTTLCRTICG 352
>CBIO3_ENTFA (Q832R5) Putative cobalt import ATP-binding protein cbiO 3| Length = 568 Score = 44.3 bits (103), Expect = 1e-04 Identities = 25/68 (36%), Positives = 37/68 (54%), Gaps = 1/68 (1%) Frame = +2 Query: 209 IEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKL-SGE 385 I +N F + E PTLK + +G +V + G GSGKS+L CI G +P + GE Sbjct: 6 ITFNNFSFQYHSQSE-PTLKGIQLTIYEGEKVLIVGPSGSGKSTLAQCINGLIPNIYEGE 64 Query: 386 VKTCGTMA 409 ++ T+A Sbjct: 65 IQGTATVA 72
>MDR17_ARATH (Q9M1Q9) Multidrug resistance protein 17 (P-glycoprotein 21)| Length = 1292 Score = 43.9 bits (102), Expect = 2e-04 Identities = 27/77 (35%), Positives = 38/77 (49%) Frame = +2 Query: 209 IEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEV 388 IE++N FS+ PE + + G VA+ G GSGKS+++S I SGEV Sbjct: 403 IELNNVNFSYPARPEEQIFRGFSLSISSGSTVALVGQSGSGKSTVVSLIERFYDPQSGEV 462 Query: 389 KTCGTMAYVSQTAWIQS 439 + G Q WI+S Sbjct: 463 RIDGINLKEFQLKWIRS 479 Score = 36.6 bits (83), Expect = 0.030 Identities = 19/76 (25%), Positives = 37/76 (48%) Frame = +2 Query: 209 IEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEV 388 IE+ + F + P++ +DL + G +A+ G GSGKS++++ + SG++ Sbjct: 1048 IELRHISFKYPSRPDVQIFQDLCLSIRAGKTIALVGESGSGKSTVIALLQRFYDPDSGQI 1107 Query: 389 KTCGTMAYVSQTAWIQ 436 G Q W++ Sbjct: 1108 TLDGVEIKTLQLKWLR 1123
>Y1618_HAEIN (P45275) Hypothetical ABC transporter ATP-binding protein HI1618| Length = 217 Score = 43.9 bits (102), Expect = 2e-04 Identities = 25/67 (37%), Positives = 38/67 (56%) Frame = +2 Query: 200 NVAIEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLS 379 N + V+N C +G ++DL+F + R+ V G +GSGK++LL +LG VP Sbjct: 11 NNMLAVNNLCIERNGRA---IIQDLSFTLEGQKRLFVQGEIGSGKTTLLLALLGFVPVTK 67 Query: 380 GEVKTCG 400 GE+K G Sbjct: 68 GEIKLFG 74
>CBIO2_MYCMS (Q6MSQ1) Cobalt import ATP-binding protein cbiO 2| Length = 408 Score = 43.5 bits (101), Expect = 2e-04 Identities = 24/71 (33%), Positives = 41/71 (57%), Gaps = 1/71 (1%) Frame = +2 Query: 197 SNVAIEVSNGCFSWDGSPELPT-LKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPK 373 S++AIE+++ F + PE P + D++F QG V + G GSGKS++ ++G + Sbjct: 136 SDIAIEINHLSFKY--GPEFPNAIDDVSFTINQGEYVTIIGHNGSGKSTISKILIGVLNA 193 Query: 374 LSGEVKTCGTM 406 GE+K G + Sbjct: 194 QHGEIKIFGNI 204
>CBIO1_METAC (Q8TIX0) Cobalt import ATP-binding protein cbiO 1| Length = 326 Score = 43.5 bits (101), Expect = 2e-04 Identities = 35/94 (37%), Positives = 48/94 (51%), Gaps = 2/94 (2%) Frame = +2 Query: 125 DRIASFLCLEELPTDAVDRLPSGSSNVAIEVSNGCFSWDGSPELP--TLKDLNFQAQQGM 298 DR S E +AV+R S +EV N C + P L TL+++N + +G Sbjct: 22 DRHGSIEPGSEKAANAVER----SGIPILEVKNLCHRY---PHLDANTLEEINLKVYKGE 74 Query: 299 RVAVCGTVGSGKSSLLSCILGEVPKLSGEVKTCG 400 RVAV G G+GKS+L + G + LSGEV G Sbjct: 75 RVAVLGANGAGKSTLFKHLNGILKPLSGEVLVKG 108
>ABCBA_HUMAN (Q9NRK6) ATP-binding cassette sub-family B member 10, mitochondrial| precursor (ATP-binding cassette transporter 10) (ABC transporter 10 protein) (Mitochondrial ATP-binding cassette 2) (M-ABC2) Length = 738 Score = 43.1 bits (100), Expect = 3e-04 Identities = 24/78 (30%), Positives = 37/78 (47%) Frame = +2 Query: 206 AIEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGE 385 A+E N F++ PE+P +D + G A+ G GSGKS++LS +L SG Sbjct: 491 ALEFKNVHFAYPARPEVPIFQDFSLSIPSGSVTALVGPSGSGKSTVLSLLLRLYNPASGT 550 Query: 386 VKTCGTMAYVSQTAWIQS 439 + G W++S Sbjct: 551 ISLDGHDIRQLNPVWLRS 568
>MDR20_ARATH (Q9LSJ5) Putative multidrug resistance protein 20 (P-glycoprotein| 18) Length = 1225 Score = 43.1 bits (100), Expect = 3e-04 Identities = 23/77 (29%), Positives = 39/77 (50%) Frame = +2 Query: 209 IEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEV 388 +E ++ F++ PE P DL + G VA+ G GSGKS+++S + ++GE+ Sbjct: 347 VEFNHVKFTYPSRPETPIFDDLCLRVPSGKTVALVGGSGSGKSTVISLLQRFYDPIAGEI 406 Query: 389 KTCGTMAYVSQTAWIQS 439 G Q W++S Sbjct: 407 LIDGLPINKLQVKWLRS 423
>MDR2_ARATH (Q8LPK2) Multidrug resistance protein 2 (P-glycoprotein 2)| Length = 1233 Score = 43.1 bits (100), Expect = 3e-04 Identities = 32/120 (26%), Positives = 55/120 (45%), Gaps = 2/120 (1%) Frame = +2 Query: 35 SALATFRVLQEPIYNLPDTISMMIQTKVSLDRIASFLCLEELPTDAVDRLPSGSSNV--A 208 S + TF VL + +T+++ +AS + + T V +NV Sbjct: 930 SVMKTFMVLIVTALAMGETLALAPDLLKGNQMVASVFEILDRKTQIVGETSEELNNVEGT 989 Query: 209 IEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEV 388 IE+ FS+ P++ +D + + G +A+ G GSGKSS++S IL +G+V Sbjct: 990 IELKGVHFSYPSRPDVVIFRDFDLIVRAGKSMALVGQSGSGKSSVISLILRFYDPTAGKV 1049 Score = 35.4 bits (80), Expect = 0.066 Identities = 22/76 (28%), Positives = 34/76 (44%) Frame = +2 Query: 209 IEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEV 388 I+ + FS+ P++ LN G VA+ G GSGKS+++S I +SG V Sbjct: 361 IQFKDATFSYPSRPDVVIFDRLNLAIPAGKIVALVGGSGSGKSTVISLIERFYEPISGAV 420 Query: 389 KTCGTMAYVSQTAWIQ 436 G W++ Sbjct: 421 LLDGNNISELDIKWLR 436
>MDR12_ARATH (Q9C7F2) Multidrug resistance protein 12 (P-glycoprotein 14)| Length = 1247 Score = 43.1 bits (100), Expect = 3e-04 Identities = 30/111 (27%), Positives = 56/111 (50%), Gaps = 4/111 (3%) Frame = +2 Query: 38 ALATFRVLQEPIYNLPDTISM---MIQTKVSLDRIASFLCLE-ELPTDAVDRLPSGSSNV 205 ++ +F VL Y++ +T+++ +++ +L + L E E+P D + Sbjct: 945 SIKSFMVLLVTAYSVAETLALTPDIVKGTQALGSVFRVLHRETEIPPDQPNSRLVTHIKG 1004 Query: 206 AIEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCIL 358 IE N F++ PE+ K+LN + G +AV G GSGKS+++ I+ Sbjct: 1005 DIEFRNVSFAYPTRPEIAIFKNLNLRVSAGKSLAVVGPSGSGKSTVIGLIM 1055 Score = 33.1 bits (74), Expect = 0.33 Identities = 25/94 (26%), Positives = 45/94 (47%), Gaps = 4/94 (4%) Frame = +2 Query: 167 DAVDRLPSGSS--NVA--IEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGK 334 ++ +RL +G++ NV IE F++ P + ++L+F G A G GSGK Sbjct: 355 ESSERLENGTTLQNVVGKIEFCGVSFAYPSRPNM-VFENLSFTIHSGKTFAFVGPSGSGK 413 Query: 335 SSLLSCILGEVPKLSGEVKTCGTMAYVSQTAWIQ 436 S+++S + SGE+ G + W++ Sbjct: 414 STIISMVQRFYEPRSGEILLDGNDIKNLKLKWLR 447
>LOLD_PASMU (Q9CN78) Lipoprotein-releasing system ATP-binding protein lolD| Length = 227 Score = 43.1 bits (100), Expect = 3e-04 Identities = 23/50 (46%), Positives = 31/50 (62%) Frame = +2 Query: 239 DGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEV 388 +GS + LKD++F Q G VA+ G+ GSGKS+LL + G SGEV Sbjct: 17 EGSQQTQVLKDVSFSMQAGELVAIVGSSGSGKSTLLHVLGGLDQPTSGEV 66
>ABCB8_HUMAN (Q9NUT2) ATP-binding cassette sub-family B member 8, mitochondrial| precursor (Mitochondrial ATP-binding cassette 1) (M-ABC1) Length = 735 Score = 42.7 bits (99), Expect = 4e-04 Identities = 32/145 (22%), Positives = 58/145 (40%), Gaps = 1/145 (0%) Frame = +2 Query: 5 GIPLESGKVLSALATFRVLQEPIYNLPDTISMMIQTKVSLDRIASFLCLEE-LPTDAVDR 181 G L G ++S L + +Q + NL +++ + R+ ++ L +P Sbjct: 403 GQQLTGGDLMSFLVASQTVQRSMANLSVLFGQVVRGLSAGARVFEYMALNPCIPLSGGCC 462 Query: 182 LPSGSSNVAIEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILG 361 +P ++ N CFS+ P LKD G VA+ G G GK+++ S + Sbjct: 463 VPKEQLRGSVTFQNVCFSYPCRPGFEVLKDFTLTLPPGKIVALVGQSGGGKTTVASLLER 522 Query: 362 EVPKLSGEVKTCGTMAYVSQTAWIQ 436 +G V G +W++ Sbjct: 523 FYDPTAGVVMLDGRDLRTLDPSWLR 547
>CBIO_PHOPR (Q6LQ00) Putative cobalt import ATP-binding protein cbiO| Length = 564 Score = 42.7 bits (99), Expect = 4e-04 Identities = 23/56 (41%), Positives = 34/56 (60%) Frame = +2 Query: 203 VAIEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVP 370 + IE SN F + + E PTLK++N +G +V + G GSGKS+L C+ G +P Sbjct: 1 MTIEFSNFTFKY-WALEKPTLKNINLTIGKGEKVVIVGPSGSGKSTLGQCLNGLIP 55 Score = 37.4 bits (85), Expect = 0.017 Identities = 21/65 (32%), Positives = 37/65 (56%) Frame = +2 Query: 194 SSNVAIEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPK 373 +S + V+N +S+DG TL D++F +G V++ G GSGKS++ I+G + Sbjct: 294 NSERLLTVNNLSYSYDGIKN--TLDDVSFHINKGEFVSILGKNGSGKSTITRLIMGVLEP 351 Query: 374 LSGEV 388 +G + Sbjct: 352 DTGSI 356
>CBIO1_MESFL (Q6F1W5) Cobalt import ATP-binding protein cbiO 1| Length = 406 Score = 42.7 bits (99), Expect = 4e-04 Identities = 31/83 (37%), Positives = 45/83 (54%), Gaps = 1/83 (1%) Frame = +2 Query: 203 VAIEVSNGCFSWDGSPELP-TLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLS 379 VAI+V N F + +P+ P L D++F+ G VAV G GSGKS+L ++G + Sbjct: 137 VAIKVENLKFKY--APDFPYALNDVSFEINDGEYVAVIGHNGSGKSTLSKMLIGVLSAQE 194 Query: 380 GEVKTCGTMAYVSQTAWIQSGKF 448 G V G + V+Q Q+ KF Sbjct: 195 GHVSIYGNV--VTQDNLDQARKF 215
>MDR14_ARATH (Q9M3B9) Multidrug resistance protein 14 (P-glycoprotein 20)| Length = 1408 Score = 42.7 bits (99), Expect = 4e-04 Identities = 35/144 (24%), Positives = 68/144 (47%), Gaps = 6/144 (4%) Frame = +2 Query: 26 KVLSALATFRVLQEPIYNLPDTISM---MIQTKVSLDRIASFLCLEELPT---DAVDRLP 187 K+ +A+ + V + L + + +++ + SL I+ F ++ +PT D L Sbjct: 1094 KLSTAITEYMVFSFATFALVEPFGLAPYILKRRKSL--ISVFEIVDRVPTIEPDDNSALK 1151 Query: 188 SGSSNVAIEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEV 367 + +IE+ N F + PE+ L + + + G VAV G GSGKS+++S + Sbjct: 1152 PPNVYGSIELKNVDFCYPTRPEILVLSNFSLKISGGQTVAVVGVSGSGKSTIISLVERYY 1211 Query: 368 PKLSGEVKTCGTMAYVSQTAWIQS 439 ++G+V G + W++S Sbjct: 1212 DPVAGQVLLDGRDLKLYNLRWLRS 1235 Score = 34.7 bits (78), Expect = 0.11 Identities = 24/77 (31%), Positives = 33/77 (42%) Frame = +2 Query: 209 IEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEV 388 IE N FS+ PE+P L VA+ G GSGKSS++ + GEV Sbjct: 414 IEFRNVYFSYLSRPEIPILSGFYLTVPAKKAVALVGRNGSGKSSIIPLMERFYDPTLGEV 473 Query: 389 KTCGTMAYVSQTAWIQS 439 G + W++S Sbjct: 474 LLDGENIKNLKLEWLRS 490
>CBIO4_LACPL (Q88ZZ2) Putative cobalt import ATP-binding protein cbiO 4| Length = 566 Score = 42.4 bits (98), Expect = 5e-04 Identities = 23/69 (33%), Positives = 37/69 (53%), Gaps = 5/69 (7%) Frame = +2 Query: 209 IEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPK----- 373 I N F ++ E PTL+D+N G +V + G GSGKS+L C+ G +P+ Sbjct: 6 ISFKNFSFQYNSQTE-PTLRDINLDIYPGEKVLIAGPSGSGKSTLGRCLNGLIPQSYPGT 64 Query: 374 LSGEVKTCG 400 ++G+ + G Sbjct: 65 VTGQARIAG 73
>MDR6_ARATH (Q8LPT1) Multidrug resistance protein 6 (P-glycoprotein 6)| Length = 1407 Score = 42.4 bits (98), Expect = 5e-04 Identities = 36/144 (25%), Positives = 66/144 (45%), Gaps = 6/144 (4%) Frame = +2 Query: 26 KVLSALATFRVLQEPIYNLPDTISM---MIQTKVSLDRIASFLCLEELPT---DAVDRLP 187 K+ +AL + V + L + + +++ + SL + F ++ +PT D L Sbjct: 1093 KLSTALTEYMVFSFATFALVEPFGLAPYILKRRRSLASV--FEIIDRVPTIEPDDTSALS 1150 Query: 188 SGSSNVAIEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEV 367 + +IE+ N F + PE+ L + + + G VAV G GSGKS+++S I Sbjct: 1151 PPNVYGSIELKNIDFCYPTRPEVLVLSNFSLKVNGGQTVAVVGVSGSGKSTIISLIERYY 1210 Query: 368 PKLSGEVKTCGTMAYVSQTAWIQS 439 ++G+V G W++S Sbjct: 1211 DPVAGQVLLDGRDLKSYNLRWLRS 1234 Score = 34.7 bits (78), Expect = 0.11 Identities = 24/77 (31%), Positives = 33/77 (42%) Frame = +2 Query: 209 IEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEV 388 IE N FS+ PE+P L VA+ G GSGKSS++ + GEV Sbjct: 412 IEFRNVYFSYLSRPEIPILSGFYLTVPAKKAVALVGRNGSGKSSIIPLMERFYDPTLGEV 471 Query: 389 KTCGTMAYVSQTAWIQS 439 G + W++S Sbjct: 472 LLDGENIKNLKLEWLRS 488
>CBIO3_STRMU (Q93D97) Putative cobalt import ATP-binding protein cbiO 3| Length = 558 Score = 42.4 bits (98), Expect = 5e-04 Identities = 20/56 (35%), Positives = 33/56 (58%) Frame = +2 Query: 209 IEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKL 376 IE + F +D E PTLK++ ++G +V + G GSGKS++ C+ G +P + Sbjct: 5 IEFKDFSFKYDAQAE-PTLKEITLSIEKGEKVLIIGPSGSGKSTIGHCLNGIIPNI 59
>Y4FO_RHISN (P55453) Putative ABC transporter ATP-binding protein y4fO| Length = 339 Score = 42.0 bits (97), Expect = 7e-04 Identities = 21/49 (42%), Positives = 28/49 (57%) Frame = +2 Query: 242 GSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEV 388 G P + ++DLN G V++ G GSGKSS+L I G +P L G V Sbjct: 21 GFPGMTVVRDLNLDVADGAFVSLLGPSGSGKSSVLRTIAGLLPALGGRV 69
>AAPP_RHILV (Q52815) General L-amino acid transport ATP-binding protein aapP| Length = 257 Score = 42.0 bits (97), Expect = 7e-04 Identities = 23/75 (30%), Positives = 40/75 (53%) Frame = +2 Query: 179 RLPSGSSNVAIEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCIL 358 +L ++ VA+E+ N W G + L+D+N + +G R+ + G GSGKS+++ CI Sbjct: 8 KLTVSATEVAVEIVN-MNKWYG--DFHVLRDINLKVMRGERIVIAGPSGSGKSTMIRCIN 64 Query: 359 GEVPKLSGEVKTCGT 403 G++ GT Sbjct: 65 RLEEHQKGKIVVDGT 79
>CBIO4_METAC (Q8TSC8) Putative cobalt import ATP-binding protein cbiO 4| Length = 641 Score = 42.0 bits (97), Expect = 7e-04 Identities = 23/60 (38%), Positives = 36/60 (60%) Frame = +2 Query: 209 IEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEV 388 IE+ + +++ G E PTLK +N + ++G V + G G GKS+LL + G +P SG V Sbjct: 10 IEIKDLWYTYPGRTE-PTLKGVNLKIEEGEFVLLTGPTGCGKSTLLKTLNGIIPHESGGV 68 Score = 39.7 bits (91), Expect = 0.003 Identities = 20/46 (43%), Positives = 28/46 (60%) Frame = +2 Query: 263 LKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEVKTCG 400 LK +N + ++G RVA+ GT GSGKS+LL + + G VK G Sbjct: 354 LKGINLEIRKGERVAIMGTNGSGKSTLLLNLAAMLKPYKGSVKVFG 399
>CBIO4_CLOPE (Q8XK20) Putative cobalt import ATP-binding protein cbiO 4| Length = 568 Score = 42.0 bits (97), Expect = 7e-04 Identities = 21/53 (39%), Positives = 32/53 (60%), Gaps = 5/53 (9%) Frame = +2 Query: 257 PTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVP-----KLSGEVKTCG 400 PTL ++N +G +V + G GSGKS+L +CI G +P ++SG +K G Sbjct: 22 PTLNNINLTIYEGEKVLIAGPSGSGKSTLANCINGLIPFSTDIEISGSLKIKG 74 Score = 37.4 bits (85), Expect = 0.017 Identities = 20/60 (33%), Positives = 34/60 (56%) Frame = +2 Query: 209 IEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEV 388 +E N FS+D ++ L D+NF+ +G V+V G G+GKS++ I G + G++ Sbjct: 303 LEFKNVSFSYDKKKDI--LSDINFKINRGDIVSVVGKNGAGKSTISKIICGFFKESKGDI 360
>CBIO2_STRMU (Q8DRR9) Cobalt import ATP-binding protein cbiO 2| Length = 280 Score = 42.0 bits (97), Expect = 7e-04 Identities = 21/60 (35%), Positives = 36/60 (60%) Frame = +2 Query: 209 IEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEV 388 IE+ N F +D + E PTL +++F + G +++ G GSGKS+ + I G + SG++ Sbjct: 6 IELKNVTFRYDENQEKPTLNNISFHVKHGEWLSIIGHNGSGKSTTVRLIDGLLEAESGQI 65
>PHNC2_ANASP (Q8YUI9) Phosphonates import ATP-binding protein phnC 2 (EC| 3.6.3.28) Length = 244 Score = 42.0 bits (97), Expect = 7e-04 Identities = 25/68 (36%), Positives = 38/68 (55%) Frame = +2 Query: 197 SNVAIEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKL 376 S+ IE N ++ GS P L +++ +QG V + G G+GKS+LL ++G VP + Sbjct: 2 SDYVIECHNLETAYVGSLNRPILNEISCHIKQGEFVVLLGLNGAGKSTLLRSLVGLVPLV 61 Query: 377 SGEVKTCG 400 GEV G Sbjct: 62 RGEVHING 69
>CBIO1_ONYPE (Q6YRJ4) Putative cobalt import ATP-binding protein cbiO 1| Length = 588 Score = 41.6 bits (96), Expect = 0.001 Identities = 22/53 (41%), Positives = 30/53 (56%) Frame = +2 Query: 245 SPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEVKTCGT 403 S + PTL +N +G +V + G GSGKS+ L CI G +P S + K GT Sbjct: 17 SQQTPTLNQINLTIYEGQKVLIVGKNGSGKSTFLKCINGLIPH-SYQGKITGT 68
>TROB_TREPA (P96117) Zinc transport system ATP-binding protein troB| Length = 266 Score = 41.6 bits (96), Expect = 0.001 Identities = 20/48 (41%), Positives = 31/48 (64%) Frame = +2 Query: 257 PTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEVKTCG 400 P L D++ + +G+ A+ G G+GKS+LL I+G +P SGEV+ G Sbjct: 24 PVLWDVDVRIPEGVIEAIIGPNGAGKSTLLKAIMGLLPLASGEVRVFG 71
>ZURA_LISIN (Q926D8) Zinc uptake system ATP-binding protein zurA| Length = 257 Score = 41.2 bits (95), Expect = 0.001 Identities = 23/67 (34%), Positives = 37/67 (55%) Frame = +2 Query: 200 NVAIEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLS 379 N IEV+N + +D L++++FQ ++G + G GSGKS++L ILG + K Sbjct: 2 NKIIEVNNVSYHYDKEH---ALENIHFQVEKGSFTGLIGPNGSGKSTMLKLILGVLKKQQ 58 Query: 380 GEVKTCG 400 G + G Sbjct: 59 GSIALFG 65
>BEXA_HAEIN (P10640) ATP-binding protein bexA| Length = 217 Score = 41.2 bits (95), Expect = 0.001 Identities = 21/62 (33%), Positives = 37/62 (59%), Gaps = 1/62 (1%) Frame = +2 Query: 209 IEVSNGCFSWDGSPELPT-LKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGE 385 I V+N C + + T LK++NF+ Q+G ++ + G G+GKS+L+ + G P SG Sbjct: 2 IRVNNVCKKYHTNSGWKTVLKNINFELQKGEKIGILGRNGAGKSTLIRLMSGVEPPTSGT 61 Query: 386 VK 391 ++ Sbjct: 62 IE 63
>CBIO1_MYCGE (P47425) Cobalt import ATP-binding protein cbiO 1| Length = 274 Score = 41.2 bits (95), Expect = 0.001 Identities = 22/82 (26%), Positives = 42/82 (51%) Frame = +2 Query: 194 SSNVAIEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPK 373 + A N FS++ ELP +++L+F +G V + G GSGKS++ + G + Sbjct: 4 TKQAACSFINVAFSYN---ELPLIRELSFSVYEGEYVCIVGHNGSGKSTISKLLTGLLKP 60 Query: 374 LSGEVKTCGTMAYVSQTAWIQS 439 +GE+K G +++++ Sbjct: 61 QAGEIKIFGKTVDFDNVSYLRN 82
>CBIO3_BACCR (Q81CT8) Putative cobalt import ATP-binding protein cbiO 3| Length = 566 Score = 40.8 bits (94), Expect = 0.002 Identities = 19/43 (44%), Positives = 24/43 (55%) Frame = +2 Query: 242 GSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVP 370 G PTL D+ F G +V + G GSGKS+L CI G +P Sbjct: 15 GHAAQPTLSDITFHIYPGEKVLIAGRSGSGKSTLAHCINGLIP 57
>MDR21_ARATH (Q9LSJ2) Putative multidrug resistance protein 21 (P-glycoprotein| 22) Length = 1262 Score = 40.8 bits (94), Expect = 0.002 Identities = 22/70 (31%), Positives = 33/70 (47%) Frame = +2 Query: 230 FSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEVKTCGTMA 409 F + PE P DL + G VA+ G GSGKS+++S + + GE+ G Sbjct: 386 FMYSSRPETPIFDDLCLRIPSGKSVALVGGSGSGKSTVISLLQRFYDPIVGEILIDGVSI 445 Query: 410 YVSQTAWIQS 439 Q W++S Sbjct: 446 KKLQVKWLRS 455
>MDR10_ARATH (Q9SGY1) Multidrug resistance protein 10 (P-glycoprotein 10)| Length = 1316 Score = 40.8 bits (94), Expect = 0.002 Identities = 31/110 (28%), Positives = 47/110 (42%), Gaps = 2/110 (1%) Frame = +2 Query: 35 SALATFRVLQEPIYNLPDTISMMIQTKVSLDRIASFLCLEELPTDAVDRLPSGSSNV--A 208 S + TF VL + + +++ + S L + T V SNV Sbjct: 1011 SVMKTFMVLIVTALVMGEVLALAPDLLKGNQMVVSVFELLDRRTQVVGDTGEELSNVEGT 1070 Query: 209 IEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCIL 358 IE+ FS+ P++ D N G +A+ G GSGKSS+LS +L Sbjct: 1071 IELKGVHFSYPSRPDVTIFSDFNLLVPSGKSMALVGQSGSGKSSVLSLVL 1120 Score = 33.9 bits (76), Expect = 0.19 Identities = 23/82 (28%), Positives = 35/82 (42%) Frame = +2 Query: 191 GSSNVAIEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVP 370 G+ N I + F++ P++ LNF G VA+ G GSGKS+++S I Sbjct: 392 GNVNGDILFKDVTFTYPSRPDVVIFDKLNFVIPAGKVVALVGGSGSGKSTMISLIERFYE 451 Query: 371 KLSGEVKTCGTMAYVSQTAWIQ 436 G V G W++ Sbjct: 452 PTDGAVMLDGNDIRYLDLKWLR 473
>CBIO4_CLOAB (Q97JB8) Putative cobalt import ATP-binding protein cbiO 4| Length = 279 Score = 40.8 bits (94), Expect = 0.002 Identities = 20/46 (43%), Positives = 29/46 (63%) Frame = +2 Query: 263 LKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEVKTCG 400 L D+N ++G RVA+ G G+GKS+L + + G + SGEVK G Sbjct: 20 LHDINMSIKKGERVAILGPNGAGKSTLFNMLNGIISPTSGEVKING 65
>MDLA_BUCBP (Q89A97) Multidrug resistance-like ATP-binding protein mdlA (EC| 3.6.3.44) Length = 579 Score = 40.8 bits (94), Expect = 0.002 Identities = 30/129 (23%), Positives = 61/129 (47%), Gaps = 4/129 (3%) Frame = +2 Query: 14 LESGKVLSALATFRVLQEPIYNLPDTISMMIQTKVSLDRIASF----LCLEELPTDAVDR 181 + +G+++S + ++ P+ +++ + S DRI S L + + + Sbjct: 272 ISTGELMSFILYLGLIIWPMLAFAWMFNIIERGSASWDRIKSMINNNLFIHKKKYKNISN 331 Query: 182 LPSGSSNVAIEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILG 361 +P +EV F + S + LK++NF+ + G + +CG GSGKS+LL I Sbjct: 332 IPG-----ILEVKINYFKYSKSNKT-ILKNINFKIRPGQILGICGPTGSGKSTLLKLIQR 385 Query: 362 EVPKLSGEV 388 ++ G++ Sbjct: 386 QIELYDGKI 394
>CBIO3_STRA5 (Q8DY60) Putative cobalt import ATP-binding protein cbiO 3| Length = 558 Score = 40.4 bits (93), Expect = 0.002 Identities = 22/54 (40%), Positives = 31/54 (57%) Frame = +2 Query: 209 IEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVP 370 IE + F +D E PTLK +N +G +V + G GSGKS+L C+ G +P Sbjct: 5 IEWKDFTFQYDVQSE-PTLKGINLSIPKGEKVLILGPSGSGKSTLGHCLNGIIP 57
>CBIO3_STRA3 (Q8E3S6) Putative cobalt import ATP-binding protein cbiO 3| Length = 558 Score = 40.4 bits (93), Expect = 0.002 Identities = 22/54 (40%), Positives = 31/54 (57%) Frame = +2 Query: 209 IEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVP 370 IE + F +D E PTLK +N +G +V + G GSGKS+L C+ G +P Sbjct: 5 IEWKDFTFQYDVQSE-PTLKGINLSIPKGEKVLILGPSGSGKSTLGHCLNGIIP 57
>ABCD3_HUMAN (P28288) ATP-binding cassette sub-family D member 3 (70 kDa| peroxisomal membrane protein) (PMP70) Length = 659 Score = 40.4 bits (93), Expect = 0.002 Identities = 25/63 (39%), Positives = 35/63 (55%), Gaps = 3/63 (4%) Frame = +2 Query: 263 LKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEVKT---CGTMAYVSQTAWI 433 ++DLNF+ + G V +CG G GKSSL +LGE+ L G T G + YV Q ++ Sbjct: 456 IRDLNFEVRSGANVLICGPNGCGKSSLFR-VLGELWPLFGGRLTKPERGKLFYVPQRPYM 514 Query: 434 QSG 442 G Sbjct: 515 TLG 517
>MSBA_PHOLL (Q7N6C6) Lipid A export ATP-binding/permease protein msbA| Length = 581 Score = 40.4 bits (93), Expect = 0.002 Identities = 29/114 (25%), Positives = 55/114 (48%) Frame = +2 Query: 14 LESGKVLSALATFRVLQEPIYNLPDTISMMIQTKVSLDRIASFLCLEELPTDAVDRLPSG 193 L +GK+ ++ L P+ +L + + + + + S L +E+ D +L Sbjct: 278 LTAGKITVVFSSMIALMRPLKSLTNVNAQFQRGMAACQTLFSILDMEQEKDDG--KLELK 335 Query: 194 SSNVAIEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCI 355 +N IE N F + + ELP L++++ G VA+ G GSGKS++ + + Sbjct: 336 KANGDIEFRNVTFCYP-TKELPALQNISMYIPAGKIVALVGRSGSGKSTIANLL 388
>CBIO_PROFR (Q51719) Cobalt import ATP-binding protein cbiO| Length = 297 Score = 40.4 bits (93), Expect = 0.002 Identities = 21/54 (38%), Positives = 32/54 (59%), Gaps = 1/54 (1%) Frame = +2 Query: 242 GSPELPTLKD-LNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEVKTCG 400 G P+ P + D +N +G R+A+ G GSGK++LLSC+ G + G V+ G Sbjct: 13 GFPDRPRVLDTVNLAIGRGTRLALLGANGSGKTTLLSCLAGSLKPTGGAVERDG 66
>HMT1_SCHPO (Q02592) Heavy metal tolerance protein precursor| Length = 830 Score = 40.4 bits (93), Expect = 0.002 Identities = 36/120 (30%), Positives = 59/120 (49%), Gaps = 4/120 (3%) Frame = +2 Query: 41 LATFRV-LQEPIYNLPDTISMMIQTKVSLDRIASFLCLEELPTDAVDRLPSGSSNVA--- 208 L T+ + LQ+P+ N T+ +Q + +D EE PT V++ + V Sbjct: 527 LLTYMIQLQQPL-NFFGTLYRSLQNSI-IDTERLLEIFEEKPT-VVEKPNAPDLKVTQGK 583 Query: 209 IEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEV 388 + S+ F++D P P L D+NF AQ G +A+ G G GKS+++ +L SG + Sbjct: 584 VIFSHVSFAYD--PRKPVLSDINFVAQPGKVIALVGESGGGKSTIMRILLRFFDVNSGSI 641
>CBIO2_METAC (Q8TIW9) Cobalt import ATP-binding protein cbiO 2| Length = 276 Score = 40.4 bits (93), Expect = 0.002 Identities = 21/58 (36%), Positives = 37/58 (63%) Frame = +2 Query: 212 EVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGE 385 ++ N +S+ G E+ LKD++F+ G ++++ G+ GSGKS+LLS + G + GE Sbjct: 6 DLKNISYSYVG--EITVLKDISFKVDPGEQISIIGSNGSGKSTLLSLLDGLIYPTVGE 61
>CBIO4_BACC1 (Q737I0) Putative cobalt import ATP-binding protein cbiO 4| Length = 566 Score = 40.4 bits (93), Expect = 0.002 Identities = 21/50 (42%), Positives = 30/50 (60%) Frame = +2 Query: 257 PTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEVKTCGTM 406 PT+KD+ F G +V + G GSGKS+L C+ G +P S E + GT+ Sbjct: 20 PTVKDVTFHIYPGEKVLIAGRSGSGKSTLAHCMNGLIP-FSYEGTSTGTI 68 Score = 29.6 bits (65), Expect = 3.6 Identities = 17/51 (33%), Positives = 30/51 (58%) Frame = +2 Query: 209 IEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILG 361 ++V N FS+ ++ L ++NF +G VA+ G G+GKS+L ++G Sbjct: 300 LKVENLSFSYPNKQKV--LDNVNFSLFKGEIVALLGHNGAGKSTLAHSLIG 348
>CBIO3_BACHK (Q6HI76) Putative cobalt import ATP-binding protein cbiO 3| Length = 566 Score = 40.0 bits (92), Expect = 0.003 Identities = 17/38 (44%), Positives = 24/38 (63%) Frame = +2 Query: 257 PTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVP 370 PT+KD+ F G +V + G GSGKS+L C+ G +P Sbjct: 20 PTVKDITFHIYPGEKVLIAGRSGSGKSTLAHCMNGLIP 57
>CBIO3_BACAN (Q81PZ8) Putative cobalt import ATP-binding protein cbiO 3| Length = 566 Score = 40.0 bits (92), Expect = 0.003 Identities = 17/38 (44%), Positives = 24/38 (63%) Frame = +2 Query: 257 PTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVP 370 PT+KD+ F G +V + G GSGKS+L C+ G +P Sbjct: 20 PTVKDITFHIYPGEKVLIAGRSGSGKSTLAHCMNGLIP 57
>YMEB_LACLA (Q02151) Hypothetical ABC transporter ATP-binding protein ymeB| Length = 259 Score = 39.7 bits (91), Expect = 0.003 Identities = 21/47 (44%), Positives = 26/47 (55%) Frame = +2 Query: 263 LKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEVKTCGT 403 LKD+ ++ G + G GSGKSSLL IL E K SGE+ T Sbjct: 19 LKDITWKVNPGENWVILGLNGSGKSSLLKLILAEEWKTSGEITVLNT 65
>Y1303_MYCBO (P63398) Hypothetical ABC transporter ATP-binding protein Mb1303c| Length = 631 Score = 39.7 bits (91), Expect = 0.003 Identities = 26/112 (23%), Positives = 50/112 (44%) Frame = +2 Query: 23 GKVLSALATFRVLQEPIYNLPDTISMMIQTKVSLDRIASFLCLEELPTDAVDRLPSGSSN 202 G + + + R P+ L + + S +R+ L E + LP+ + Sbjct: 337 GSIQAFIQYIRQFNMPLSQLAGMYNALQSGVASAERVFDVLDEPEESPEPEPELPNLTGR 396 Query: 203 VAIEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCIL 358 V E N + P P ++DL+ A+ G VA+ G G+GK++L++ ++ Sbjct: 397 VEFEHVNFAYL----PGTPVIRDLSLVAEPGSTVAIVGPTGAGKTTLVNLLM 444
>Y1272_MYCTU (P63397) Hypothetical ABC transporter ATP-binding protein| Rv1272c/MT1310 Length = 631 Score = 39.7 bits (91), Expect = 0.003 Identities = 26/112 (23%), Positives = 50/112 (44%) Frame = +2 Query: 23 GKVLSALATFRVLQEPIYNLPDTISMMIQTKVSLDRIASFLCLEELPTDAVDRLPSGSSN 202 G + + + R P+ L + + S +R+ L E + LP+ + Sbjct: 337 GSIQAFIQYIRQFNMPLSQLAGMYNALQSGVASAERVFDVLDEPEESPEPEPELPNLTGR 396 Query: 203 VAIEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCIL 358 V E N + P P ++DL+ A+ G VA+ G G+GK++L++ ++ Sbjct: 397 VEFEHVNFAYL----PGTPVIRDLSLVAEPGSTVAIVGPTGAGKTTLVNLLM 444
>YTRE_BACSU (O34392) Hypothetical ABC transporter ATP-binding protein ytrE| Length = 231 Score = 39.7 bits (91), Expect = 0.003 Identities = 21/63 (33%), Positives = 33/63 (52%), Gaps = 1/63 (1%) Frame = +2 Query: 251 ELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEVKTCGT-MAYVSQTA 427 E+P LKD++ +G + G GSGKS+LL+ I G + G + GT + ++ Sbjct: 21 EVPVLKDVSLSVAKGEIACIVGRSGSGKSTLLNLISGYISPTKGRIVINGTDVTGFNEKE 80 Query: 428 WIQ 436 W Q Sbjct: 81 WAQ 83
>ZURA_LISMO (Q9XDA6) Zinc uptake system ATP-binding protein zurA| Length = 257 Score = 39.3 bits (90), Expect = 0.005 Identities = 22/64 (34%), Positives = 35/64 (54%) Frame = +2 Query: 209 IEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEV 388 IEV+N + +D L++++FQ +G + G GSGKS++L ILG + K G + Sbjct: 5 IEVNNVSYHYDKEH---ALENIHFQVAKGSFTGLIGPNGSGKSTMLKLILGVLKKQQGSI 61 Query: 389 KTCG 400 G Sbjct: 62 SLFG 65
>CBIO3_STAAR (Q6GDC0) Putative cobalt import ATP-binding protein cbiO 3| Length = 570 Score = 39.3 bits (90), Expect = 0.005 Identities = 21/49 (42%), Positives = 28/49 (57%), Gaps = 1/49 (2%) Frame = +2 Query: 245 SPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVP-KLSGEV 388 S PTL+++N G +V V G GSGKS+ +CI G +P K G V Sbjct: 17 SQATPTLQNINVDIYPGEKVLVVGASGSGKSTFANCINGLIPFKTKGNV 65
>CTRD_NEIMB (P32016) Capsule polysaccharide export ATP-binding protein ctrD (EC| 3.6.3.38) (Capsular-polysaccharide-transporting ATPase) Length = 216 Score = 39.3 bits (90), Expect = 0.005 Identities = 16/43 (37%), Positives = 29/43 (67%) Frame = +2 Query: 263 LKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEVK 391 L D++F+ ++G ++ + G G+GKS+L+ I G P +GE+K Sbjct: 21 LHDISFKMEKGEKIGILGRNGAGKSTLIRLISGVEPPTTGEIK 63
>CTRD_NEIMA (P57013) Capsule polysaccharide export ATP-binding protein ctrD (EC| 3.6.3.38) (Capsular-polysaccharide-transporting ATPase) Length = 216 Score = 39.3 bits (90), Expect = 0.005 Identities = 16/43 (37%), Positives = 29/43 (67%) Frame = +2 Query: 263 LKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEVK 391 L D++F+ ++G ++ + G G+GKS+L+ I G P +GE+K Sbjct: 21 LHDISFKMEKGEKIGILGRNGAGKSTLIRLISGVEPPTTGEIK 63
>BZTD_RHOCA (Q52666) Glutamate/glutamine/aspartate/asparagine transport| ATP-binding protein bztD Length = 263 Score = 38.9 bits (89), Expect = 0.006 Identities = 19/54 (35%), Positives = 31/54 (57%) Frame = +2 Query: 194 SSNVAIEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCI 355 S +AI++S W G + L+D+N +G R+ + G GSGKS+++ CI Sbjct: 18 SDEIAIQISQ-MNKWYG--QFHVLRDINLTVHRGERIVIAGPSGSGKSTMIRCI 68
>CBIO3_STAAN (Q7A342) Putative cobalt import ATP-binding protein cbiO 3| Length = 570 Score = 38.9 bits (89), Expect = 0.006 Identities = 20/49 (40%), Positives = 28/49 (57%), Gaps = 1/49 (2%) Frame = +2 Query: 245 SPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVP-KLSGEV 388 S PTL+++N G +V V G GSGKS+ +CI G +P K G + Sbjct: 17 SQATPTLQNINVDIYPGEKVLVVGASGSGKSTFANCINGLIPFKTKGNI 65
>CBIO3_STAAM (Q99QV7) Putative cobalt import ATP-binding protein cbiO 3| Length = 570 Score = 38.9 bits (89), Expect = 0.006 Identities = 20/49 (40%), Positives = 28/49 (57%), Gaps = 1/49 (2%) Frame = +2 Query: 245 SPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVP-KLSGEV 388 S PTL+++N G +V V G GSGKS+ +CI G +P K G + Sbjct: 17 SQATPTLQNINVDIYPGEKVLVVGASGSGKSTFANCINGLIPFKTKGNI 65
>CBIO3_STAAC (Q5HCL3) Putative cobalt import ATP-binding protein cbiO 3| Length = 570 Score = 38.9 bits (89), Expect = 0.006 Identities = 20/49 (40%), Positives = 28/49 (57%), Gaps = 1/49 (2%) Frame = +2 Query: 245 SPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVP-KLSGEV 388 S PTL+++N G +V V G GSGKS+ +CI G +P K G + Sbjct: 17 SQATPTLQNINVDIYPGEKVLVVGASGSGKSTFANCINGLIPFKTKGNI 65
>ABCBA_MOUSE (Q9JI39) ATP-binding cassette sub-family B member 10, mitochondrial| precursor (ATP-binding cassette transporter 10) (ABC transporter 10 protein) (ABC-mitochondrial erythroid protein) (ABC-me protein) Length = 715 Score = 38.9 bits (89), Expect = 0.006 Identities = 23/78 (29%), Positives = 36/78 (46%) Frame = +2 Query: 206 AIEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGE 385 A+E N F++ PE+ +D + G A+ G GSGKS+++S +L SG Sbjct: 456 ALEFRNVHFTYPARPEVSVFQDFSLSIPSGSVTALVGPSGSGKSTVVSLLLRLYDPNSGT 515 Query: 386 VKTCGTMAYVSQTAWIQS 439 V G W++S Sbjct: 516 VSLDGHDIRQLNPVWLRS 533
>CBIO5_METMA (Q8PVG9) Putative cobalt import ATP-binding protein cbiO 5| Length = 581 Score = 38.9 bits (89), Expect = 0.006 Identities = 21/46 (45%), Positives = 27/46 (58%) Frame = +2 Query: 263 LKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEVKTCG 400 LK +N + +G RVAV GT GSGKS+LL + + G VK G Sbjct: 329 LKGINLEIHRGERVAVMGTNGSGKSTLLLNLAAMLRPYKGNVKIFG 374 Score = 35.4 bits (80), Expect = 0.066 Identities = 22/69 (31%), Positives = 37/69 (53%), Gaps = 5/69 (7%) Frame = +2 Query: 209 IEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPK----- 373 IE+ + +++ G E TLK ++ + ++G V + G G GKS+LL + G +P Sbjct: 10 IEIRDLWYTYPGRAET-TLKGIDLKIKEGEFVLLTGPTGCGKSTLLKTLNGIIPHESEGI 68 Query: 374 LSGEVKTCG 400 SG +K G Sbjct: 69 FSGSIKISG 77
>NODI_AZOCA (Q07756) Nod factor export ATP-binding protein I (Nodulation| ATP-binding protein I) Length = 320 Score = 38.9 bits (89), Expect = 0.006 Identities = 20/55 (36%), Positives = 29/55 (52%) Frame = +2 Query: 236 WDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEVKTCG 400 W + L+ L+ ++G R + GT G+GKSSL++ ILG P G V G Sbjct: 21 WKKRGGIDVLRGLDMYVRRGERYGIMGTNGAGKSSLINIILGLTPPDRGTVTVFG 75
>MDR1_ARATH (Q9ZR72) Multidrug resistance protein 1 (P-glycoprotein 1) (AtPgp1)| Length = 1286 Score = 38.9 bits (89), Expect = 0.006 Identities = 21/64 (32%), Positives = 35/64 (54%) Frame = +2 Query: 209 IEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEV 388 +E+ + FS+ P++ +DL+ +A+ G +A+ G G GKSS++S I SG V Sbjct: 1024 VELKHIDFSYPSRPDIQIFRDLSLRARAGKTLALVGPSGCGKSSVISLIQRFYEPSSGRV 1083 Query: 389 KTCG 400 G Sbjct: 1084 MIDG 1087 Score = 37.0 bits (84), Expect = 0.023 Identities = 21/76 (27%), Positives = 37/76 (48%) Frame = +2 Query: 209 IEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEV 388 +E+ N FS+ P++ L + G +A+ G+ GSGKS+++S I SG+V Sbjct: 368 VELKNVDFSYPSRPDVKILNNFCLSVPAGKTIALVGSSGSGKSTVVSLIERFYDPNSGQV 427 Query: 389 KTCGTMAYVSQTAWIQ 436 G + W++ Sbjct: 428 LLDGQDLKTLKLRWLR 443
>CBIO1_BACCR (Q81J16) Cobalt import ATP-binding protein cbiO 1| Length = 280 Score = 38.9 bits (89), Expect = 0.006 Identities = 22/74 (29%), Positives = 36/74 (48%) Frame = +2 Query: 209 IEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEV 388 + + N F + G+ LKD++F +G V++ G GSGKS+L + G +G + Sbjct: 6 LRIENISFQYPGAATY-ALKDVSFSLYEGEWVSIIGQNGSGKSTLAKLLNGLFLPEAGTI 64 Query: 389 KTCGTMAYVSQTAW 430 TM +T W Sbjct: 65 TVNDTMVLSEETVW 78
>CBIO3_BACSU (O34362) Putative cobalt import ATP-binding protein cbiO 3| Length = 490 Score = 38.9 bits (89), Expect = 0.006 Identities = 28/97 (28%), Positives = 49/97 (50%), Gaps = 2/97 (2%) Frame = +2 Query: 104 IQTKVSLDRIAS--FLCLEELPTDAVDRLPSGSSNVAIEVSNGCFSWDGSPELPTLKDLN 277 +Q K+S+ S L E +P V + + S +EVS+ F+ + KD++ Sbjct: 258 LQEKLSMPFTLSKEMLFKEPIPAGHVKKKKAPSGESVLEVSSLSFA---RGQQAIFKDIS 314 Query: 278 FQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEV 388 F ++G A+ G G+GKS+LLS + + SG++ Sbjct: 315 FSLREGSLTALVGPNGTGKSTLLSVLASLMKPQSGKI 351 Score = 37.0 bits (84), Expect = 0.023 Identities = 19/48 (39%), Positives = 29/48 (60%) Frame = +2 Query: 230 FSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPK 373 FS++ E P +D++F+ Q+G V + G G GKSSL C+ G P+ Sbjct: 15 FSYE-EDEKPVFQDISFELQKGECVLLLGPSGCGKSSLALCLNGLYPE 61
>MDR7_ARATH (Q9FHF1) Multidrug resistance protein 7 (P-glycoprotein 7)| Length = 1248 Score = 38.9 bits (89), Expect = 0.006 Identities = 25/77 (32%), Positives = 36/77 (46%) Frame = +2 Query: 209 IEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEV 388 IE+ + F + P++ + GM VA+ G GSGKS+++S I SGEV Sbjct: 357 IELRDVYFRYPARPDVQIFVGFSLTVPNGMTVALVGQSGSGKSTVISLIERFYDPESGEV 416 Query: 389 KTCGTMAYVSQTAWIQS 439 G Q WI+S Sbjct: 417 LIDGIDLKKFQVKWIRS 433
>LOLD_NITEU (Q82VL9) Lipoprotein-releasing system ATP-binding protein lolD| Length = 224 Score = 38.5 bits (88), Expect = 0.008 Identities = 20/51 (39%), Positives = 29/51 (56%) Frame = +2 Query: 236 WDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEV 388 + G+ E+P L ++ Q +G VA+ G GSGKS+LL + G GEV Sbjct: 16 FQGNLEVPVLHGIDLQVNEGEMVAIVGASGSGKSTLLHVLGGLDKPTRGEV 66
>EXPZ_BACSU (P39115) Nucleotide binding protein expZ| Length = 547 Score = 38.5 bits (88), Expect = 0.008 Identities = 23/58 (39%), Positives = 33/58 (56%), Gaps = 1/58 (1%) Frame = +2 Query: 251 ELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILG-EVPKLSGEVKTCGTMAYVSQ 421 E K+ NF Q G +VA+ G GSGK++LL+ ILG E + S V + Y++Q Sbjct: 303 ERTLFKNANFTIQHGEKVAIIGPNGSGKTTLLNIILGQETAEGSVWVSPSANIGYLTQ 360 Score = 30.4 bits (67), Expect = 2.1 Identities = 14/41 (34%), Positives = 23/41 (56%) Frame = +2 Query: 266 KDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEV 388 K +N QQG + + G G+GKS+LL I ++ G++ Sbjct: 21 KHVNASVQQGDIIGIIGKNGAGKSTLLHLIHNDLAPAQGQI 61
>TAUB_SHIFL (Q83MA0) Taurine import ATP-binding protein tauB (EC 3.6.3.36)| Length = 255 Score = 38.5 bits (88), Expect = 0.008 Identities = 18/48 (37%), Positives = 27/48 (56%) Frame = +2 Query: 257 PTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEVKTCG 400 P L+D+N + G + V G G GK++LL+ I G VP G ++ G Sbjct: 15 PALEDINLTLESGELLVVLGPSGCGKTTLLNLIAGFVPYQHGSIQLAG 62
>TAUB_ECOLI (Q47538) Taurine import ATP-binding protein tauB (EC 3.6.3.36)| Length = 255 Score = 38.5 bits (88), Expect = 0.008 Identities = 18/48 (37%), Positives = 27/48 (56%) Frame = +2 Query: 257 PTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEVKTCG 400 P L+D+N + G + V G G GK++LL+ I G VP G ++ G Sbjct: 15 PALEDINLTLESGELLVVLGPSGCGKTTLLNLIAGFVPYQHGSIQLAG 62
>TAUB_ECOL6 (Q8FKF5) Taurine import ATP-binding protein tauB (EC 3.6.3.36)| Length = 255 Score = 38.5 bits (88), Expect = 0.008 Identities = 18/48 (37%), Positives = 27/48 (56%) Frame = +2 Query: 257 PTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEVKTCG 400 P L+D+N + G + V G G GK++LL+ I G VP G ++ G Sbjct: 15 PALEDINLTLESGELLVVLGPSGCGKTTLLNLIAGFVPYQHGSIQLAG 62
>TAUB_ECO57 (Q8X5I6) Taurine import ATP-binding protein tauB (EC 3.6.3.36)| Length = 255 Score = 38.5 bits (88), Expect = 0.008 Identities = 18/48 (37%), Positives = 27/48 (56%) Frame = +2 Query: 257 PTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEVKTCG 400 P L+D+N + G + V G G GK++LL+ I G VP G ++ G Sbjct: 15 PVLEDINLTLESGELLVVLGPSGCGKTTLLNLIAGFVPYQHGSIQLAG 62
>MDR15_ARATH (Q9C7F8) Putative multidrug resistance protein 15 (P-glycoprotein 13)| Length = 1245 Score = 38.5 bits (88), Expect = 0.008 Identities = 19/50 (38%), Positives = 28/50 (56%) Frame = +2 Query: 209 IEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCIL 358 IE N F + PE+ K+LN + G +AV G GSGKS+++ I+ Sbjct: 1004 IEFRNVSFVYPTRPEIDIFKNLNLRVSAGKSLAVVGPSGSGKSTVIGLIM 1053 Score = 33.9 bits (76), Expect = 0.19 Identities = 26/95 (27%), Positives = 45/95 (47%), Gaps = 4/95 (4%) Frame = +2 Query: 164 TDAVDRLPSGSS--NVA--IEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSG 331 +++ RL G++ NVA IE F++ P + ++L+F + G A G GSG Sbjct: 353 SESSQRLDEGTTLQNVAGRIEFQKVSFAYPSRPNM-VFENLSFTIRSGKTFAFVGPSGSG 411 Query: 332 KSSLLSCILGEVPKLSGEVKTCGTMAYVSQTAWIQ 436 KS+++S + SGE+ G + W + Sbjct: 412 KSTIISMVQRFYEPNSGEILLDGNDIKSLKLKWFR 446
>PHNC_LACLA (Q9CIQ6) Phosphonates import ATP-binding protein phnC (EC 3.6.3.28)| Length = 246 Score = 38.5 bits (88), Expect = 0.008 Identities = 17/33 (51%), Positives = 23/33 (69%) Frame = +2 Query: 263 LKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILG 361 L D+N Q QG VA+ GT G+GKS+L+ C+ G Sbjct: 18 LTDVNLQINQGEFVAIIGTSGAGKSTLIRCVNG 50
>CYDD_HAEIN (P45082) Transport ATP-binding protein cydD| Length = 586 Score = 38.5 bits (88), Expect = 0.008 Identities = 35/110 (31%), Positives = 50/110 (45%), Gaps = 7/110 (6%) Frame = +2 Query: 125 DRIASFLCLEELPTDAVDRLPSGSSNVAIEVSN-GCFSWDGSPELPTLKDLNFQAQQGMR 301 D I FL + L ++ S S V I N S GS K LNFQ Sbjct: 322 DAIVDFLESDYLTVHQNEKTISLESAVEISAENLVVLSTQGSA---LTKPLNFQIPANHN 378 Query: 302 VAVCGTVGSGKSSLLSCILGEVP-----KLSG-EVKTCGTMAYVSQTAWI 433 VA+ G G+GK+SL++ ILG +P K++G E++ + AW+ Sbjct: 379 VALVGQSGAGKTSLMNVILGFLPYEGSLKINGQELRESNLADWRKHIAWV 428
>UUP_ECOLI (P43672) ABC transporter ATP-binding protein uup| Length = 635 Score = 38.5 bits (88), Expect = 0.008 Identities = 20/67 (29%), Positives = 37/67 (55%) Frame = +2 Query: 188 SGSSNVAIEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEV 367 S S + E+ + C+ +G +KD + Q +G ++A+ G G GK++LL +LG++ Sbjct: 313 SRSGKIVFEMEDVCYQVNGKQ---LVKDFSAQVLRGDKIALIGPNGCGKTTLLKLMLGQL 369 Query: 368 PKLSGEV 388 SG + Sbjct: 370 QADSGRI 376
>LOLD_VIBVY (Q7MJ01) Lipoprotein-releasing system ATP-binding protein lolD| Length = 227 Score = 38.5 bits (88), Expect = 0.008 Identities = 24/51 (47%), Positives = 33/51 (64%), Gaps = 1/51 (1%) Frame = +2 Query: 239 DGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLS-GEV 388 +G E LK ++F+ +QG VA+ GT GSGKS+LL ILG + + GEV Sbjct: 16 EGEFETEVLKGVDFELEQGELVAIVGTSGSGKSTLLH-ILGALDDATHGEV 65
>LOLD_VIBVU (Q8DAV6) Lipoprotein-releasing system ATP-binding protein lolD| Length = 227 Score = 38.5 bits (88), Expect = 0.008 Identities = 24/51 (47%), Positives = 33/51 (64%), Gaps = 1/51 (1%) Frame = +2 Query: 239 DGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLS-GEV 388 +G E LK ++F+ +QG VA+ GT GSGKS+LL ILG + + GEV Sbjct: 16 EGEFETEVLKGVDFELEQGELVAIVGTSGSGKSTLLH-ILGALDDATHGEV 65
>LOLD_PSEPK (Q88KY4) Lipoprotein-releasing system ATP-binding protein lolD| Length = 227 Score = 38.5 bits (88), Expect = 0.008 Identities = 23/57 (40%), Positives = 32/57 (56%), Gaps = 1/57 (1%) Frame = +2 Query: 233 SWDGSPE-LPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEVKTCG 400 S+D PE + L LN + + G RVA+ G+ GSGKS+LL+ + G G V G Sbjct: 15 SYDEGPESVQVLSGLNLELRAGERVAIVGSSGSGKSTLLNLLGGLDRPTQGSVWLAG 71
>CBIO3_OCEIH (Q8ES39) Putative cobalt import ATP-binding protein cbiO 3| Length = 527 Score = 38.5 bits (88), Expect = 0.008 Identities = 15/33 (45%), Positives = 24/33 (72%) Frame = +2 Query: 263 LKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILG 361 LKD++F +QG + + G G+GKS+LL C++G Sbjct: 293 LKDISFSVKQGEFITILGENGAGKSTLLQCLIG 325
>TAGH_ENTFA (Q831L8) Teichoic acids export ATP-binding protein tagH (EC| 3.6.3.40) Length = 447 Score = 38.1 bits (87), Expect = 0.010 Identities = 19/57 (33%), Positives = 31/57 (54%) Frame = +2 Query: 248 PELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEVKTCGTMAYVS 418 P LK ++ G + + G GSGKS+L + I G P+ SGE++ G ++ +S Sbjct: 38 PTFWALKGVSLDVYSGETIGIIGLNGSGKSTLSNIISGITPQTSGELEINGEVSIIS 94
>CBIO3_STAAW (Q8NUH8) Putative cobalt import ATP-binding protein cbiO 3| Length = 570 Score = 38.1 bits (87), Expect = 0.010 Identities = 20/49 (40%), Positives = 27/49 (55%), Gaps = 1/49 (2%) Frame = +2 Query: 245 SPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVP-KLSGEV 388 S PTL+ +N G +V V G GSGKS+ +CI G +P K G + Sbjct: 17 SQATPTLQKINVDIYPGEKVLVVGASGSGKSTFANCINGLIPFKTKGNI 65
>CBIO3_STAAS (Q6G5Z1) Putative cobalt import ATP-binding protein cbiO 3| Length = 570 Score = 38.1 bits (87), Expect = 0.010 Identities = 20/49 (40%), Positives = 27/49 (55%), Gaps = 1/49 (2%) Frame = +2 Query: 245 SPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVP-KLSGEV 388 S PTL+ +N G +V V G GSGKS+ +CI G +P K G + Sbjct: 17 SQATPTLQKINVDIYPGEKVLVVGASGSGKSTFANCINGLIPFKTKGNI 65
>ARTP_HAEIN (P45092) Arginine transport ATP-binding protein artP| Length = 243 Score = 38.1 bits (87), Expect = 0.010 Identities = 27/63 (42%), Positives = 39/63 (61%), Gaps = 1/63 (1%) Frame = +2 Query: 203 VAIEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCI-LGEVPKLS 379 +AI V N F + S TL D+N +A++G V + G G+GKS+L+ + L EVPK S Sbjct: 1 MAIRVKNLNFFYGSSQ---TLFDINLEAEEGDTVVLLGPSGAGKSTLIRTLNLLEVPK-S 56 Query: 380 GEV 388 GE+ Sbjct: 57 GEL 59
>ABCD3_RAT (P16970) ATP-binding cassette sub-family D member 3 (70 kDa| peroxisomal membrane protein) (PMP70) Length = 658 Score = 38.1 bits (87), Expect = 0.010 Identities = 24/63 (38%), Positives = 35/63 (55%), Gaps = 3/63 (4%) Frame = +2 Query: 263 LKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEVKT---CGTMAYVSQTAWI 433 ++DL+F+ + G V +CG G GKSSL +LGE+ L G T G + YV Q ++ Sbjct: 455 IQDLSFEVRSGANVLICGPNGCGKSSLFR-VLGELWPLFGGHLTKPERGKLFYVPQRPYM 513 Query: 434 QSG 442 G Sbjct: 514 TLG 516
>PHNC_YERPS (Q66D26) Phosphonates import ATP-binding protein phnC (EC 3.6.3.28)| Length = 278 Score = 38.1 bits (87), Expect = 0.010 Identities = 17/42 (40%), Positives = 27/42 (64%) Frame = +2 Query: 263 LKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEV 388 L ++NF+ G VA+ G G+GKS+LL + G +P +GE+ Sbjct: 41 LDNINFELHAGEFVAIIGRSGAGKSTLLHILNGTIPTSAGEI 82
>PHNC_YERPE (Q8ZGU5) Phosphonates import ATP-binding protein phnC (EC 3.6.3.28)| Length = 278 Score = 38.1 bits (87), Expect = 0.010 Identities = 17/42 (40%), Positives = 27/42 (64%) Frame = +2 Query: 263 LKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEV 388 L ++NF+ G VA+ G G+GKS+LL + G +P +GE+ Sbjct: 41 LDNINFELHAGEFVAIIGRSGAGKSTLLHILNGTIPTSAGEI 82
>UUP2_HAEIN (P45167) ABC transporter ATP-binding protein uup-2| Length = 459 Score = 38.1 bits (87), Expect = 0.010 Identities = 20/56 (35%), Positives = 34/56 (60%), Gaps = 3/56 (5%) Frame = +2 Query: 263 LKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEVKTCGT---MAYVSQ 421 LKD + +G ++A+ G G GK++ + +LGE+ SG+++ CGT +AY Q Sbjct: 147 LKDFSTTILRGDKIALVGPNGCGKTTFIKLLLGEIQPTSGKIR-CGTKLEIAYFDQ 201
>SPAT_BACSU (P33116) Subtilin transport ATP-binding protein spaT| Length = 614 Score = 38.1 bits (87), Expect = 0.010 Identities = 28/122 (22%), Positives = 57/122 (46%) Frame = +2 Query: 23 GKVLSALATFRVLQEPIYNLPDTISMMIQTKVSLDRIASFLCLEELPTDAVDRLPSGSSN 202 G V+S + + ++Q ++ +I + + + ++++ FL L+E + + P Sbjct: 292 GNVMSYIRSVSLVQNHSQSIMTSIYSIYNSNLYMNQLYEFLELKEEKSQG-HKKPIVEPI 350 Query: 203 VAIEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSG 382 ++ N F + E TLK +N +G RVA+ G GSGK + + + G G Sbjct: 351 HSVVFQNVSFIYPNQGE-QTLKHINVSLHKGERVAIVGPNGSGKKTFIKLLTGLYEVHEG 409 Query: 383 EV 388 ++ Sbjct: 410 DI 411
>LOLD_SHEON (Q8EEV5) Lipoprotein-releasing system ATP-binding protein lolD| Length = 230 Score = 38.1 bits (87), Expect = 0.010 Identities = 25/64 (39%), Positives = 36/64 (56%), Gaps = 1/64 (1%) Frame = +2 Query: 239 DGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPK-LSGEVKTCGTMAYV 415 DG L D++ Q +G ++A+ GT GSGKS+LL I+G + K SG+V G Y Sbjct: 17 DGDVTTQVLSDVDLQVFKGEQLAIVGTSGSGKSTLLH-IMGTLDKPSSGKVLLAGEDLYQ 75 Query: 416 SQTA 427 +A Sbjct: 76 VSSA 79
>MDR3_CAEEL (P34713) Multidrug resistance protein 3 (EC 3.6.3.44)| (P-glycoprotein C) Length = 1268 Score = 38.1 bits (87), Expect = 0.010 Identities = 20/70 (28%), Positives = 35/70 (50%) Frame = +2 Query: 230 FSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEVKTCGTMA 409 F++ PEL LK ++F+ G VA+ G G GKS+ + ++ + +G +K G Sbjct: 383 FTYPTRPELKILKGVSFEVNPGETVALVGHSGCGKSTSIGLLMRFYNQCAGMIKLDGIPI 442 Query: 410 YVSQTAWIQS 439 W++S Sbjct: 443 QEYNIRWLRS 452
>MDR19_ARATH (Q9LSJ6) Putative multidrug resistance protein 19 (P-glycoprotein| 17) Length = 1240 Score = 38.1 bits (87), Expect = 0.010 Identities = 22/77 (28%), Positives = 38/77 (49%) Frame = +2 Query: 209 IEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEV 388 +E ++ F++ PE DL + G VA+ G GSGKS+++S + ++GE+ Sbjct: 359 VEFNHVKFTYLSRPETTIFDDLCLKIPAGKTVALVGGSGSGKSTVISLLQRFYDPIAGEI 418 Query: 389 KTCGTMAYVSQTAWIQS 439 G Q W++S Sbjct: 419 LIDGVSIDKLQVNWLRS 435
>CBIO1_BACC1 (Q73F67) Cobalt import ATP-binding protein cbiO 1| Length = 280 Score = 38.1 bits (87), Expect = 0.010 Identities = 23/74 (31%), Positives = 35/74 (47%) Frame = +2 Query: 209 IEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEV 388 + N F + G+ LKD++F +G V+V G GSGKS+L + G +G + Sbjct: 6 LRTENISFQYPGAATY-ALKDVSFSLYEGEWVSVIGQNGSGKSTLAKLLNGLFLPEAGTI 64 Query: 389 KTCGTMAYVSQTAW 430 TM +T W Sbjct: 65 TVNDTMVLSEETVW 78
>CBIO2_STRPY (P0C0E9) Cobalt import ATP-binding protein cbiO| Length = 279 Score = 38.1 bits (87), Expect = 0.010 Identities = 21/70 (30%), Positives = 37/70 (52%) Frame = +2 Query: 209 IEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEV 388 IE+ F++ E PTL ++F +QG +++ G GSGKS+ + I G + SG + Sbjct: 5 IELKKVTFNYHKDQEKPTLDGVSFHVKQGEWLSIIGHNGSGKSTTIRLIDGLLEPESGSI 64 Query: 389 KTCGTMAYVS 418 G + ++ Sbjct: 65 IVDGDLLTIT 74
>CBIO2_STRP8 (Q7CMM7) Cobalt import ATP-binding protein cbiO 2| Length = 279 Score = 38.1 bits (87), Expect = 0.010 Identities = 21/70 (30%), Positives = 37/70 (52%) Frame = +2 Query: 209 IEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEV 388 IE+ F++ E PTL ++F +QG +++ G GSGKS+ + I G + SG + Sbjct: 5 IELKKVTFNYHKDQEKPTLDGVSFHVKQGEWLSIIGHNGSGKSTTIRLIDGLLEPESGSI 64 Query: 389 KTCGTMAYVS 418 G + ++ Sbjct: 65 IVDGDLLTIT 74
>CBIO2_STRP6 (Q5X9B5) Cobalt import ATP-binding protein cbiO 2| Length = 279 Score = 38.1 bits (87), Expect = 0.010 Identities = 21/70 (30%), Positives = 37/70 (52%) Frame = +2 Query: 209 IEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEV 388 IE+ F++ E PTL ++F +QG +++ G GSGKS+ + I G + SG + Sbjct: 5 IELKKVTFNYHKDQEKPTLDGVSFHVKQGEWLSIIGHNGSGKSTTIRLIDGLLEPESGSI 64 Query: 389 KTCGTMAYVS 418 G + ++ Sbjct: 65 IVDGDLLTIT 74
>CBIO2_STRP3 (Q877W5) Cobalt import ATP-binding protein cbiO 2| Length = 279 Score = 38.1 bits (87), Expect = 0.010 Identities = 21/70 (30%), Positives = 37/70 (52%) Frame = +2 Query: 209 IEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEV 388 IE+ F++ E PTL ++F +QG +++ G GSGKS+ + I G + SG + Sbjct: 5 IELKKVTFNYHKDQEKPTLDGVSFHVKQGEWLSIIGHNGSGKSTTIRLIDGLLEPESGSI 64 Query: 389 KTCGTMAYVS 418 G + ++ Sbjct: 65 IVDGDLLTIT 74
>CBIO2_STRP1 (P0C0E8) Cobalt import ATP-binding protein cbiO 2| Length = 279 Score = 38.1 bits (87), Expect = 0.010 Identities = 21/70 (30%), Positives = 37/70 (52%) Frame = +2 Query: 209 IEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEV 388 IE+ F++ E PTL ++F +QG +++ G GSGKS+ + I G + SG + Sbjct: 5 IELKKVTFNYHKDQEKPTLDGVSFHVKQGEWLSIIGHNGSGKSTTIRLIDGLLEPESGSI 64 Query: 389 KTCGTMAYVS 418 G + ++ Sbjct: 65 IVDGDLLTIT 74
>UUP1_HAEIN (Q57242) ABC transporter ATP-binding protein uup-1| Length = 647 Score = 38.1 bits (87), Expect = 0.010 Identities = 20/56 (35%), Positives = 34/56 (60%), Gaps = 3/56 (5%) Frame = +2 Query: 263 LKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEVKTCGT---MAYVSQ 421 LKD + +G ++A+ G G GK++ + +LGE+ SG+++ CGT +AY Q Sbjct: 335 LKDFSTTILRGDKIALVGPNGCGKTTFIKLLLGEIQPTSGKIR-CGTKLEIAYFDQ 389 Score = 29.3 bits (64), Expect = 4.7 Identities = 18/61 (29%), Positives = 30/61 (49%) Frame = +2 Query: 209 IEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEV 388 I ++NG S+ + P L + V + G G+GKS+LL I G+V G++ Sbjct: 4 ISLTNGYLSFS---DAPLLDHAELHIEPNECVCLVGRNGAGKSTLLKIIAGDVLMDDGKI 60 Query: 389 K 391 + Sbjct: 61 Q 61
>APRD_PSEAE (Q03024) Alkaline protease secretion ATP-binding protein aprD| Length = 593 Score = 37.7 bits (86), Expect = 0.013 Identities = 25/59 (42%), Positives = 29/59 (49%), Gaps = 3/59 (5%) Frame = +2 Query: 233 SWDGSP---ELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEVKTCG 400 S D +P E TL+ L G V V G GSGKSSL +LG P L G V+ G Sbjct: 336 SLDAAPPGSEARTLRGLTLAIPAGSVVGVIGPSGSGKSSLARVVLGIWPTLHGSVRLDG 394
>ABCD3_MOUSE (P55096) ATP-binding cassette sub-family D member 3 (70 kDa| peroxisomal membrane protein) (PMP70) (PMP68) Length = 659 Score = 37.7 bits (86), Expect = 0.013 Identities = 24/63 (38%), Positives = 35/63 (55%), Gaps = 3/63 (4%) Frame = +2 Query: 263 LKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEVKT---CGTMAYVSQTAWI 433 ++DL+F+ + G V +CG G GKSSL +LGE+ L G T G + YV Q ++ Sbjct: 456 IQDLSFEVRSGNHVLICGPNGRGKSSLFR-VLGELWPLFGGRLTKPERGKLFYVPQRPYM 514 Query: 434 QSG 442 G Sbjct: 515 TLG 517
>TAGH_BACSK (Q5WCL2) Teichoic acids export ATP-binding protein tagH (EC| 3.6.3.40) Length = 360 Score = 37.7 bits (86), Expect = 0.013 Identities = 16/52 (30%), Positives = 29/52 (55%) Frame = +2 Query: 263 LKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEVKTCGTMAYVS 418 LKD+N + +G + V G GSGKS++ + + +P GE+ G + ++ Sbjct: 42 LKDINLEVYEGETIGVIGINGSGKSTISNILASVIPPTEGEMTVNGETSLIA 93
>LOLD_HAEDU (Q7VMV4) Lipoprotein-releasing system ATP-binding protein lolD| Length = 226 Score = 37.7 bits (86), Expect = 0.013 Identities = 21/53 (39%), Positives = 30/53 (56%) Frame = +2 Query: 230 FSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEV 388 F +GS + L D++F G VA+ G+ GSGKS+LL + G +GEV Sbjct: 13 FYEEGSQSVQVLNDVSFTINTGGLVAIVGSSGSGKSTLLHILGGLDKPTTGEV 65
>PHNC_HALSA (Q9HNI8) Phosphonates import ATP-binding protein phnC (EC 3.6.3.28)| Length = 280 Score = 37.7 bits (86), Expect = 0.013 Identities = 18/50 (36%), Positives = 29/50 (58%) Frame = +2 Query: 251 ELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEVKTCG 400 ++ L+D++F+ G V + G G+GKS+LL C+ G +G VK G Sbjct: 15 DVDALEDVSFEILDGEFVVILGESGAGKSTLLRCLNGLTEPTTGSVKIDG 64
>LAGD_LACLA (P59852) Lactococcin-G-processing and transport ATP-binding protein| lagD (EC 3.4.22.-) Length = 703 Score = 37.7 bits (86), Expect = 0.013 Identities = 25/112 (22%), Positives = 54/112 (48%) Frame = +2 Query: 23 GKVLSALATFRVLQEPIYNLPDTISMMIQTKVSLDRIASFLCLEELPTDAVDRLPSGSSN 202 G++++ A EP+ N+ + M + +V+ R+ + + + + N Sbjct: 407 GQLITYNALLVFFTEPLQNIINLQVKMQKARVANKRLNEIMSISPEQRNTNINISKNIFN 466 Query: 203 VAIEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCIL 358 I++ FS++ +LP L+D++ + +VA+ G GSGKS+L ++ Sbjct: 467 KDIKLDKVSFSYN--MKLPVLRDVSLEIYSKSKVALVGVSGSGKSTLAKLLV 516
>MODF_ECOLI (P31060) Putative molybdenum transport ATP-binding protein modF| (Photorepair protein phrA) Length = 490 Score = 37.7 bits (86), Expect = 0.013 Identities = 23/75 (30%), Positives = 40/75 (53%), Gaps = 1/75 (1%) Frame = +2 Query: 209 IEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPK-LSGE 385 I ++NG S++ + P L +L++Q G + G G+GKS+LLS + G+ P+ S + Sbjct: 261 IVLNNGVVSYN---DRPILNNLSWQVNPGEHWQIVGPNGAGKSTLLSLVTGDHPQGYSND 317 Query: 386 VKTCGTMAYVSQTAW 430 + G +T W Sbjct: 318 LTLFGRRRGSGETIW 332 Score = 30.4 bits (67), Expect = 2.1 Identities = 14/27 (51%), Positives = 18/27 (66%) Frame = +2 Query: 305 AVCGTVGSGKSSLLSCILGEVPKLSGE 385 A G+ GSGKS+L + GE+P L GE Sbjct: 33 AFVGSNGSGKSALARALAGELPLLKGE 59
>CYDC_HAEIN (P45081) Transport ATP-binding protein cydC| Length = 576 Score = 37.7 bits (86), Expect = 0.013 Identities = 22/60 (36%), Positives = 31/60 (51%) Frame = +2 Query: 209 IEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEV 388 I N FS+ L LK+L +QG ++A+ G GSGKSSLL ++ GE+ Sbjct: 338 ISAKNLNFSYPEQETL-VLKNLTLDLEQGKKIAILGKTGSGKSSLLQLLVRNYDANQGEL 396
>YFC8_YEAST (P43569) Probable ATP-dependent transporter YFL028C| Length = 289 Score = 37.7 bits (86), Expect = 0.013 Identities = 24/68 (35%), Positives = 36/68 (52%) Frame = +2 Query: 197 SNVAIEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKL 376 S AIEV N + + S + P++ D+N Q R V G G+GKS+LL + G+ L Sbjct: 3 SQFAIEVRNLTYKFKESSD-PSVVDINLQIPWNTRSLVVGANGAGKSTLLKLLSGKHLCL 61 Query: 377 SGEVKTCG 400 G++ G Sbjct: 62 DGKILVNG 69
>YHDZ_ECOLI (P45769) Hypothetical amino-acid ABC transporter ATP-binding| protein yhdZ Length = 252 Score = 37.7 bits (86), Expect = 0.013 Identities = 17/40 (42%), Positives = 24/40 (60%) Frame = +2 Query: 236 WDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCI 355 W G + LK++N Q G R+ +CG GSGKS+ + CI Sbjct: 21 WYG--QFHVLKNINLTVQPGERIVLCGPSGSGKSTTIRCI 58
>Y1470_HAEIN (Q57399) Hypothetical ABC transporter ATP-binding protein HI1470| Length = 253 Score = 37.4 bits (85), Expect = 0.017 Identities = 24/74 (32%), Positives = 38/74 (51%) Frame = +2 Query: 200 NVAIEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLS 379 N A+ V N F + L + LNF +G +AV G G GKS+LL +LG + Sbjct: 2 NKALSVENLGFYYQAENFL--FQQLNFDLNKGDILAVLGQNGCGKSTLLDLLLGIHRPIQ 59 Query: 380 GEVKTCGTMAYVSQ 421 G+++ ++ +V Q Sbjct: 60 GKIEVYQSIGFVPQ 73
>CBIO3_CLOTE (Q897I2) Putative cobalt import ATP-binding protein cbiO 3| Length = 437 Score = 37.4 bits (85), Expect = 0.017 Identities = 21/62 (33%), Positives = 35/62 (56%) Frame = +2 Query: 203 VAIEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSG 382 V +E+ F ++ ++ LKDL+F+ +G + V G G+GKS+L I G + K G Sbjct: 184 VVMEIEKLNFEYERGYKI--LKDLSFKLHRGEIMTVMGENGAGKSTLFKIIAGMIDKYKG 241 Query: 383 EV 388 +V Sbjct: 242 KV 243
>MDR1_CRIGR (P21448) Multidrug resistance protein 1 (EC 3.6.3.44) (P-glycoprotein| 1) (CD243 antigen) Length = 1276 Score = 37.4 bits (85), Expect = 0.017 Identities = 17/70 (24%), Positives = 37/70 (52%) Frame = +2 Query: 230 FSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEVKTCGTMA 409 F++ P++P L+ LN + ++G +A+ G+ G GKS+++ + ++G V G Sbjct: 1039 FNYPTRPDIPVLQGLNLEVKKGQTLALVGSSGCGKSTVVQLLERFYDPMAGTVFLDGKEV 1098 Query: 410 YVSQTAWIQS 439 W+++ Sbjct: 1099 NQLNVQWLRA 1108 Score = 34.7 bits (78), Expect = 0.11 Identities = 17/49 (34%), Positives = 26/49 (53%) Frame = +2 Query: 209 IEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCI 355 +E N FS+ ++ LK LN + Q G VA+ G G GKS+ + + Sbjct: 389 LEFKNIHFSYPSRKDVQILKGLNLKVQSGQTVALVGNSGCGKSTTVQLL 437
>MSBA_SALTY (P63359) Lipid A export ATP-binding/permease protein msbA| Length = 582 Score = 37.4 bits (85), Expect = 0.017 Identities = 26/114 (22%), Positives = 54/114 (47%) Frame = +2 Query: 14 LESGKVLSALATFRVLQEPIYNLPDTISMMIQTKVSLDRIASFLCLEELPTDAVDRLPSG 193 L +G + ++ L P+ +L + + + + + + L E+ + + Sbjct: 279 LTAGTITVVFSSMIALMRPLKSLTNVNAQFQRGMAACQTLFAILDSEQEKDEGKRVIDRA 338 Query: 194 SSNVAIEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCI 355 + + +E N F++ G E+P L+++N + G VA+ G GSGKS++ S I Sbjct: 339 TGD--LEFRNVTFTYPGR-EVPALRNINLKIPAGKTVALVGRSGSGKSTIASLI 389
>MSBA_SALTI (P63360) Lipid A export ATP-binding/permease protein msbA| Length = 582 Score = 37.4 bits (85), Expect = 0.017 Identities = 26/114 (22%), Positives = 54/114 (47%) Frame = +2 Query: 14 LESGKVLSALATFRVLQEPIYNLPDTISMMIQTKVSLDRIASFLCLEELPTDAVDRLPSG 193 L +G + ++ L P+ +L + + + + + + L E+ + + Sbjct: 279 LTAGTITVVFSSMIALMRPLKSLTNVNAQFQRGMAACQTLFAILDSEQEKDEGKRVIDRA 338 Query: 194 SSNVAIEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCI 355 + + +E N F++ G E+P L+++N + G VA+ G GSGKS++ S I Sbjct: 339 TGD--LEFRNVTFTYPGR-EVPALRNINLKIPAGKTVALVGRSGSGKSTIASLI 389
>MDR1_RAT (P43245) Multidrug resistance protein 1 (EC 3.6.3.44)| (P-glycoprotein 1) (CD243 antigen) Length = 1277 Score = 37.4 bits (85), Expect = 0.017 Identities = 20/64 (31%), Positives = 31/64 (48%) Frame = +2 Query: 209 IEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEV 388 +E N F++ E+ LK LN + + G VA+ G G GKS+ + + + GEV Sbjct: 391 LEFKNVYFNYPSRSEVKILKGLNLKVKSGQTVALVGNSGCGKSTTVQLLQRLYDPIEGEV 450 Query: 389 KTCG 400 G Sbjct: 451 SIDG 454
>CBIO1_STRCO (Q9KXJ6) Putative cobalt import ATP-binding protein cbiO 1| Length = 563 Score = 37.4 bits (85), Expect = 0.017 Identities = 18/50 (36%), Positives = 32/50 (64%) Frame = +2 Query: 233 SWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSG 382 ++DG+ E PT++ ++F+ +G V + G G GKS++L + G VP +G Sbjct: 10 TYDGATE-PTVRAVDFEVPEGELVLLAGPSGVGKSTVLGAVGGLVPHFTG 58 Score = 33.5 bits (75), Expect = 0.25 Identities = 22/69 (31%), Positives = 35/69 (50%) Frame = +2 Query: 185 PSGSSNVAIEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGE 364 PS + A EV + D + L+ ++ G VA+ G G+GKS+LLS ++G Sbjct: 309 PSAPTPYAAEVRSLAVRRD---RVQALRHVDLTVSPGETVALMGRNGAGKSTLLSALVGL 365 Query: 365 VPKLSGEVK 391 V +G V+ Sbjct: 366 VEPSAGSVR 374
>MDR8_ARATH (Q9FWX7) Multidrug resistance protein 8 (P-glycoprotein 11)| Length = 1278 Score = 37.4 bits (85), Expect = 0.017 Identities = 21/76 (27%), Positives = 37/76 (48%) Frame = +2 Query: 209 IEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEV 388 IE+ + F++ P++ +DL + G VA+ G GSGKS+++S + SG + Sbjct: 1032 IELRHLSFTYPARPDIQIFRDLCLTIRAGKTVALVGESGSGKSTVISLLQRFYDPDSGHI 1091 Query: 389 KTCGTMAYVSQTAWIQ 436 G Q W++ Sbjct: 1092 TLDGVELKKLQLKWLR 1107 Score = 33.1 bits (74), Expect = 0.33 Identities = 23/77 (29%), Positives = 33/77 (42%) Frame = +2 Query: 209 IEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEV 388 IE+ + FS+ P+ + G A+ G GSGKS+++S I SG V Sbjct: 381 IELKDVHFSYPARPDEEIFDGFSLFIPSGATAALVGESGSGKSTVISLIERFYDPKSGAV 440 Query: 389 KTCGTMAYVSQTAWIQS 439 G Q WI+S Sbjct: 441 LIDGVNLKEFQLKWIRS 457
>CYDD_BACSU (P94367) Transport ATP-binding protein cydD| Length = 575 Score = 37.4 bits (85), Expect = 0.017 Identities = 23/67 (34%), Positives = 38/67 (56%) Frame = +2 Query: 200 NVAIEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLS 379 +V + + FS+D S ++ L + +F +QG ++A+ G GSGKS+ L+ I G + S Sbjct: 334 DVTLAFRDVTFSYDNSSQV--LHNFSFTLRQGEKMALLGRSGSGKSTSLALIEGALKPDS 391 Query: 380 GEVKTCG 400 G V G Sbjct: 392 GSVTLNG 398
>CBIO2_METTH (O27739) Putative cobalt import ATP-binding protein cbiO 2| Length = 311 Score = 37.4 bits (85), Expect = 0.017 Identities = 23/61 (37%), Positives = 38/61 (62%), Gaps = 1/61 (1%) Frame = +2 Query: 209 IEVSNGCFSW-DGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGE 385 IE+ + +S+ DG+P L+ +N + ++G RVAV G G+GKS+L + G + +GE Sbjct: 2 IELRDLSYSYPDGTP---ALRGINMKVERGERVAVIGPNGAGKSTLFLHLNGILKPAAGE 58 Query: 386 V 388 V Sbjct: 59 V 59
>YEM6_YEAST (P40024) Probable ATP-dependent transporter YER036C| Length = 610 Score = 37.4 bits (85), Expect = 0.017 Identities = 19/53 (35%), Positives = 28/53 (52%) Frame = +2 Query: 230 FSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEV 388 F ++ +P + LNF R+A+ G G GKS+LL + GE+ SG V Sbjct: 400 FHYESNPSENLYEHLNFGVDMDSRIALVGPNGVGKSTLLKIMTGELTPQSGRV 452
>CBIO2_THETN (Q8R7Y4) Cobalt import ATP-binding protein cbiO 2| Length = 277 Score = 37.4 bits (85), Expect = 0.017 Identities = 17/39 (43%), Positives = 24/39 (61%) Frame = +2 Query: 227 CFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSL 343 C+S S P LKD+N Q ++G + + G GSGKS+L Sbjct: 13 CYSEGESKSPPVLKDINLQFEKGQFIGIIGHNGSGKSTL 51
>TAGH_LISIN (Q92CV8) Teichoic acids export ATP-binding protein tagH (EC| 3.6.3.40) Length = 335 Score = 37.4 bits (85), Expect = 0.017 Identities = 18/52 (34%), Positives = 29/52 (55%) Frame = +2 Query: 263 LKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEVKTCGTMAYVS 418 L+D++F G V + G GSGKS++ S + G +P GEV G + ++ Sbjct: 43 LRDVSFDIHDGETVGLIGINGSGKSTISSIMSGVIPPTQGEVVINGETSLIA 94
>TAGH_LISMF (Q720Z5) Teichoic acids export ATP-binding protein tagH (EC| 3.6.3.40) Length = 335 Score = 37.0 bits (84), Expect = 0.023 Identities = 18/52 (34%), Positives = 29/52 (55%) Frame = +2 Query: 263 LKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEVKTCGTMAYVS 418 L+D++F G V + G GSGKS++ S + G +P GEV G + ++ Sbjct: 43 LRDVSFDIHDGETVGLIGINGSGKSTISSIMSGVIPPTQGEVIINGETSLIA 94
>MDR11_ARATH (Q9LJX0) Multidrug resistance protein 11 (P-glycoprotein 19)| Length = 1252 Score = 37.0 bits (84), Expect = 0.023 Identities = 23/78 (29%), Positives = 38/78 (48%) Frame = +2 Query: 167 DAVDRLPSGSSNVAIEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLL 346 D D P + IE + F++ P++ +D N + + G A+ G GSGKSS++ Sbjct: 996 DDADADPVETIRGDIEFRHVDFAYPSRPDVMVFRDFNLRIRAGHSQALVGASGSGKSSVI 1055 Query: 347 SCILGEVPKLSGEVKTCG 400 + I L+G+V G Sbjct: 1056 AMIERFYDPLAGKVMIDG 1073 Score = 34.7 bits (78), Expect = 0.11 Identities = 20/60 (33%), Positives = 31/60 (51%) Frame = +2 Query: 209 IEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEV 388 IE + FS+ P++ ++ N G VAV G GSGKS+++S I SG++ Sbjct: 365 IEFKDVTFSYPSRPDVMIFRNFNIFFPSGKTVAVVGGSGSGKSTVVSLIERFYDPNSGQI 424
>ABCB9_RAT (Q9QYJ4) ATP-binding cassette sub-family B member 9 precursor| (ATP-binding cassette transporter 9) (ABC transporter 9 protein) (TAP-like protein) (TAPL) Length = 762 Score = 37.0 bits (84), Expect = 0.023 Identities = 29/126 (23%), Positives = 58/126 (46%), Gaps = 1/126 (0%) Frame = +2 Query: 14 LESGKVLSALATFRVLQEPIYNLPDTISMMIQTKVSLDRIASFLCLEELPTDAVD-RLPS 190 + SG +++ + VL + + ++ S ++Q + +++ F+ + PT D RL Sbjct: 436 MSSGNLIAFIIYEFVLGDCMESVGSVYSGLMQGVGAAEKVFEFI--DRQPTMVHDGRLAP 493 Query: 191 GSSNVAIEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVP 370 ++ N F++ P L++++F G A+ G GSGKSS ++ + P Sbjct: 494 DHLEGRVDFENVTFTYRTRPHTQVLQNVSFSLSPGKVTALVGPSGSGKSSCVNILENFYP 553 Query: 371 KLSGEV 388 G V Sbjct: 554 LQGGRV 559
>MSBA_SHIFL (Q83LP0) Lipid A export ATP-binding/permease protein msbA| Length = 582 Score = 37.0 bits (84), Expect = 0.023 Identities = 26/114 (22%), Positives = 54/114 (47%) Frame = +2 Query: 14 LESGKVLSALATFRVLQEPIYNLPDTISMMIQTKVSLDRIASFLCLEELPTDAVDRLPSG 193 L +G + ++ L P+ +L + + + + + + L E+ + + Sbjct: 279 LTAGTITVVFSSMIALMRPLKSLTNVNAQFQRGMAACQTLFTILDSEQEKDEGKRVIERA 338 Query: 194 SSNVAIEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCI 355 + +V E N F++ G ++P L+++N + G VA+ G GSGKS++ S I Sbjct: 339 TGDV--EFRNVTFTYPGR-DVPALRNINLKIPAGKTVALVGRSGSGKSTIASLI 389
>MSBA_ECOLI (P60752) Lipid A export ATP-binding/permease protein msbA| Length = 582 Score = 37.0 bits (84), Expect = 0.023 Identities = 26/114 (22%), Positives = 54/114 (47%) Frame = +2 Query: 14 LESGKVLSALATFRVLQEPIYNLPDTISMMIQTKVSLDRIASFLCLEELPTDAVDRLPSG 193 L +G + ++ L P+ +L + + + + + + L E+ + + Sbjct: 279 LTAGTITVVFSSMIALMRPLKSLTNVNAQFQRGMAACQTLFTILDSEQEKDEGKRVIERA 338 Query: 194 SSNVAIEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCI 355 + +V E N F++ G ++P L+++N + G VA+ G GSGKS++ S I Sbjct: 339 TGDV--EFRNVTFTYPGR-DVPALRNINLKIPAGKTVALVGRSGSGKSTIASLI 389
>MSBA_ECOL6 (Q8FJB1) Lipid A export ATP-binding/permease protein msbA| Length = 582 Score = 37.0 bits (84), Expect = 0.023 Identities = 26/114 (22%), Positives = 54/114 (47%) Frame = +2 Query: 14 LESGKVLSALATFRVLQEPIYNLPDTISMMIQTKVSLDRIASFLCLEELPTDAVDRLPSG 193 L +G + ++ L P+ +L + + + + + + L E+ + + Sbjct: 279 LTAGTITVVFSSMIALMRPLKSLTNVNAQFQRGMAACQTLFTILDSEQEKDEGKRVIERA 338 Query: 194 SSNVAIEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCI 355 + +V E N F++ G ++P L+++N + G VA+ G GSGKS++ S I Sbjct: 339 TGDV--EFRNVTFTYPGR-DVPALRNINLKIPAGKTVALVGRSGSGKSTIASLI 389
>MSBA_ECO57 (P60753) Lipid A export ATP-binding/permease protein msbA| Length = 582 Score = 37.0 bits (84), Expect = 0.023 Identities = 26/114 (22%), Positives = 54/114 (47%) Frame = +2 Query: 14 LESGKVLSALATFRVLQEPIYNLPDTISMMIQTKVSLDRIASFLCLEELPTDAVDRLPSG 193 L +G + ++ L P+ +L + + + + + + L E+ + + Sbjct: 279 LTAGTITVVFSSMIALMRPLKSLTNVNAQFQRGMAACQTLFTILDSEQEKDEGKRVIERA 338 Query: 194 SSNVAIEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCI 355 + +V E N F++ G ++P L+++N + G VA+ G GSGKS++ S I Sbjct: 339 TGDV--EFRNVTFTYPGR-DVPALRNINLKIPAGKTVALVGRSGSGKSTIASLI 389
>CBIO2_STRAW (Q82B58) Putative cobalt import ATP-binding protein cbiO 2| Length = 561 Score = 37.0 bits (84), Expect = 0.023 Identities = 18/50 (36%), Positives = 31/50 (62%) Frame = +2 Query: 233 SWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSG 382 ++DG+ E PT++ ++F +G V + G G GKS++L + G VP +G Sbjct: 10 TYDGAAE-PTVRGVDFTVPEGELVLLVGPSGVGKSTVLGAVSGLVPHFTG 58
>MSBA_WIGBR (Q8D2U8) Lipid A export ATP-binding/permease protein msbA| Length = 581 Score = 37.0 bits (84), Expect = 0.023 Identities = 18/49 (36%), Positives = 32/49 (65%) Frame = +2 Query: 209 IEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCI 355 I+ N F++ G E P+LKD+N + G VA+ G+ G+GKS++++ + Sbjct: 341 IKFKNITFTYPGK-ENPSLKDINIKISAGCTVALIGSSGAGKSTIVNLL 388
>MSBA_XANCP (Q8P8W4) Lipid A export ATP-binding/permease protein msbA| Length = 589 Score = 37.0 bits (84), Expect = 0.023 Identities = 32/125 (25%), Positives = 56/125 (44%) Frame = +2 Query: 14 LESGKVLSALATFRVLQEPIYNLPDTISMMIQTKVSLDRIASFLCLEELPTDAVDRLPSG 193 L +G + + + + + L + +M+ + S +R+ S L + P ++P Sbjct: 283 LTAGDFVVLMTSMLTIIPGLKQLTNVQNMVQRGLASAERLFSVLDSPDEPDQG--QVPLT 340 Query: 194 SSNVAIEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPK 373 + IE + + G P L D++F AQ G A+ G GSGKSSL+ I Sbjct: 341 RAKGLIEFRDVTARYPGQAN-PALADVSFVAQPGTVTAIVGRSGSGKSSLIKLIPRFYEA 399 Query: 374 LSGEV 388 SG++ Sbjct: 400 ESGQI 404
>MDLA_BUCAI (P57551) Multidrug resistance-like ATP-binding protein mdlA (EC| 3.6.3.44) Length = 589 Score = 37.0 bits (84), Expect = 0.023 Identities = 26/111 (23%), Positives = 52/111 (46%) Frame = +2 Query: 23 GKVLSALATFRVLQEPIYNLPDTISMMIQTKVSLDRIASFLCLEELPTDAVDRLPSGSSN 202 G++ S + ++ P+ L +++ + + DRI S + + D + +P Sbjct: 275 GQLTSFIMYLGLMIWPMLALAWMFNIVERGSAAWDRIHSIINKKLYIEDGKNNIPPYPGI 334 Query: 203 VAIEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCI 355 + I + + + + P+LKD+ + G + +CG GSGKS+LL I Sbjct: 335 LNINIKKFYYP---NNQKPSLKDIRILIKPGNTLGICGPTGSGKSTLLMLI 382
>CBIO1_BACHK (Q6HPN0) Cobalt import ATP-binding protein cbiO 1| Length = 280 Score = 37.0 bits (84), Expect = 0.023 Identities = 23/74 (31%), Positives = 35/74 (47%) Frame = +2 Query: 209 IEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEV 388 + N F + G+ LKD++F +G V+V G GSGKS+L + G +G + Sbjct: 6 LRTENISFQYPGAATY-ALKDVSFSLFEGEWVSVIGQNGSGKSTLAKLLNGLFLPEAGTI 64 Query: 389 KTCGTMAYVSQTAW 430 TM +T W Sbjct: 65 TVNDTMILSEETVW 78
>CBIO1_BACAN (Q81VQ2) Cobalt import ATP-binding protein cbiO 1| Length = 280 Score = 37.0 bits (84), Expect = 0.023 Identities = 23/74 (31%), Positives = 35/74 (47%) Frame = +2 Query: 209 IEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEV 388 + N F + G+ LKD++F +G V+V G GSGKS+L + G +G + Sbjct: 6 LRTENISFQYPGAATY-ALKDVSFSLFEGEWVSVIGQNGSGKSTLAKLLNGLFLPEAGTI 64 Query: 389 KTCGTMAYVSQTAW 430 TM +T W Sbjct: 65 TVNDTMILSEETVW 78
>GLTL_ECOLI (P0AAG3) Glutamate/aspartate transport ATP-binding protein gltL| Length = 241 Score = 37.0 bits (84), Expect = 0.023 Identities = 19/54 (35%), Positives = 29/54 (53%) Frame = +2 Query: 263 LKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEVKTCGTMAYVSQT 424 L D + + ++G V VCG GSGKS+L+ + G P GE+ G + +T Sbjct: 17 LTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVNDKKT 70
>GLTL_ECO57 (P0AAG4) Glutamate/aspartate transport ATP-binding protein gltL| Length = 241 Score = 37.0 bits (84), Expect = 0.023 Identities = 19/54 (35%), Positives = 29/54 (53%) Frame = +2 Query: 263 LKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEVKTCGTMAYVSQT 424 L D + + ++G V VCG GSGKS+L+ + G P GE+ G + +T Sbjct: 17 LTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVNDKKT 70
>LOLD_SALTY (P61482) Lipoprotein-releasing system ATP-binding protein lolD| Length = 233 Score = 37.0 bits (84), Expect = 0.023 Identities = 20/65 (30%), Positives = 37/65 (56%), Gaps = 1/65 (1%) Frame = +2 Query: 197 SNVAIEVSNGCFSW-DGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPK 373 + + ++ N C + +G+ + L D++F +G +A+ G+ GSGKS+LL + G Sbjct: 2 NKILLQCDNLCKRYQEGTVQTDVLHDVSFSIGEGEMMAIVGSSGSGKSTLLHLLGGLDTP 61 Query: 374 LSGEV 388 SG+V Sbjct: 62 TSGDV 66
>LOLD_SALTI (P61481) Lipoprotein-releasing system ATP-binding protein lolD| Length = 233 Score = 37.0 bits (84), Expect = 0.023 Identities = 20/65 (30%), Positives = 37/65 (56%), Gaps = 1/65 (1%) Frame = +2 Query: 197 SNVAIEVSNGCFSW-DGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPK 373 + + ++ N C + +G+ + L D++F +G +A+ G+ GSGKS+LL + G Sbjct: 2 NKILLQCDNLCKRYQEGTVQTDVLHDVSFSIGEGEMMAIVGSSGSGKSTLLHLLGGLDTP 61 Query: 374 LSGEV 388 SG+V Sbjct: 62 TSGDV 66
>CBIO_ENTFC (Q8VNL9) Cobalt import ATP-binding protein cbiO| Length = 279 Score = 36.6 bits (83), Expect = 0.030 Identities = 22/58 (37%), Positives = 30/58 (51%) Frame = +2 Query: 257 PTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEVKTCGTMAYVSQTAW 430 P LKD++F +G +A+ G GSGKS+L I G + SG VK G + W Sbjct: 21 PALKDVSFTIDKGEWIAIIGHNGSGKSTLAKTINGLLLPESGIVKV-GNQILDEENIW 77
>PHNC1_PSESM (Q889G0) Phosphonates import ATP-binding protein phnC 1 (EC| 3.6.3.28) Length = 265 Score = 36.6 bits (83), Expect = 0.030 Identities = 15/46 (32%), Positives = 30/46 (65%) Frame = +2 Query: 263 LKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEVKTCG 400 L+ L+ ++G RVA+ G G+GK++LL+ + +P +G+++ G Sbjct: 19 LRGLDLSIERGERVAIIGPSGAGKTTLLNLLASALPPSAGQLEVLG 64
>LOLD_ECOLI (P75957) Lipoprotein-releasing system ATP-binding protein lolD| Length = 233 Score = 36.6 bits (83), Expect = 0.030 Identities = 20/65 (30%), Positives = 37/65 (56%), Gaps = 1/65 (1%) Frame = +2 Query: 197 SNVAIEVSNGCFSW-DGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPK 373 + + ++ N C + +GS + L +++F +G +A+ G+ GSGKS+LL + G Sbjct: 2 NKILLQCDNLCKRYQEGSVQTDVLHNVSFSVGEGEMMAIVGSSGSGKSTLLHLLGGLDTP 61 Query: 374 LSGEV 388 SG+V Sbjct: 62 TSGDV 66
>LOLD_ECOL6 (Q8FIM7) Lipoprotein-releasing system ATP-binding protein lolD| Length = 233 Score = 36.6 bits (83), Expect = 0.030 Identities = 20/65 (30%), Positives = 37/65 (56%), Gaps = 1/65 (1%) Frame = +2 Query: 197 SNVAIEVSNGCFSW-DGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPK 373 + + ++ N C + +GS + L +++F +G +A+ G+ GSGKS+LL + G Sbjct: 2 NKILLQCDNLCKRYQEGSVQTDVLHNVSFSVGEGEMMAIVGSSGSGKSTLLHLLGGLDTP 61 Query: 374 LSGEV 388 SG+V Sbjct: 62 TSGDV 66
>LOLD_ECO57 (Q8X8E3) Lipoprotein-releasing system ATP-binding protein lolD| Length = 233 Score = 36.6 bits (83), Expect = 0.030 Identities = 20/65 (30%), Positives = 37/65 (56%), Gaps = 1/65 (1%) Frame = +2 Query: 197 SNVAIEVSNGCFSW-DGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPK 373 + + ++ N C + +GS + L +++F +G +A+ G+ GSGKS+LL + G Sbjct: 2 NKILLQCDNLCKRYQEGSVQTDVLHNVSFSVGEGEMMAIVGSSGSGKSTLLHLLGGLDTP 61 Query: 374 LSGEV 388 SG+V Sbjct: 62 TSGDV 66
>MDR3_ARATH (Q9SYI2) Putative multidrug resistance protein 3 (P-glycoprotein 3)| Length = 1229 Score = 36.6 bits (83), Expect = 0.030 Identities = 21/76 (27%), Positives = 37/76 (48%) Frame = +2 Query: 209 IEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEV 388 IE+ + F++ P++ +DL F + G VA+ G GSGKS+++S + SG + Sbjct: 984 IELCHISFTYQTRPDVQIFRDLCFAIRAGQTVALVGESGSGKSTVISLLQRFYDPDSGHI 1043 Query: 389 KTCGTMAYVSQTAWIQ 436 Q W++ Sbjct: 1044 TLDRVELKKLQLKWVR 1059 Score = 36.2 bits (82), Expect = 0.039 Identities = 24/76 (31%), Positives = 32/76 (42%) Frame = +2 Query: 209 IEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEV 388 IE+ + CFS+ P + G A+ G GSGKSS++S I SG V Sbjct: 348 IELRDVCFSYPARPMEEVFGGFSLLIPSGATAALVGESGSGKSSVISLIERFYDPSSGSV 407 Query: 389 KTCGTMAYVSQTAWIQ 436 G Q WI+ Sbjct: 408 LIDGVNLKEFQLKWIR 423
>MDR16_ARATH (Q9FWX8) Multidrug resistance protein 16 (P-glycoprotein 12)| Length = 1229 Score = 36.6 bits (83), Expect = 0.030 Identities = 21/76 (27%), Positives = 37/76 (48%) Frame = +2 Query: 209 IEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEV 388 IE+ + F++ P + +DL + G VA+ G GSGKS+++S + SG++ Sbjct: 983 IELRHLSFTYPARPGIQIFRDLCLTIRAGKTVALVGESGSGKSTVISLLQRFYDPDSGQI 1042 Query: 389 KTCGTMAYVSQTAWIQ 436 G Q W++ Sbjct: 1043 TLDGVELKKLQLKWLR 1058 Score = 32.7 bits (73), Expect = 0.43 Identities = 22/77 (28%), Positives = 34/77 (44%) Frame = +2 Query: 209 IEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEV 388 IE+ + FS+ P+ + G A+ G GSGKS++++ I +GEV Sbjct: 324 IELKDVHFSYPARPDEEIFDGFSLFIPSGATAALVGESGSGKSTVINLIERFYDPKAGEV 383 Query: 389 KTCGTMAYVSQTAWIQS 439 G Q WI+S Sbjct: 384 LIDGINLKEFQLKWIRS 400
>METN_VIBCH (Q9KTJ5) Probable D-methionine transport ATP-binding protein metN| Length = 344 Score = 36.6 bits (83), Expect = 0.030 Identities = 18/51 (35%), Positives = 28/51 (54%) Frame = +2 Query: 236 WDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEV 388 + G ++ LKD+N QG V G+ G+GKS+L+ C+ SG+V Sbjct: 12 YQGDKQIHALKDINLFIPQGTIFGVIGSSGAGKSTLIRCVNMLEKPTSGQV 62
>CBIO2_SPIKU (Q6XYZ3) Cobalt import ATP-binding protein cbiO 2| Length = 305 Score = 36.6 bits (83), Expect = 0.030 Identities = 26/78 (33%), Positives = 41/78 (52%), Gaps = 4/78 (5%) Frame = +2 Query: 200 NVAIEVSNGCFSWDGSPELP----TLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEV 367 NV I +N + + SP+ P +L+D+N + G A+ G+ GSGKS+L+ I G + Sbjct: 15 NVDITFTNVSYVY--SPKTPYEYTSLQDINVVIKPGKITAIIGSTGSGKSTLIQHINGLL 72 Query: 368 PKLSGEVKTCGTMAYVSQ 421 +G V T G + Q Sbjct: 73 IPTTGVVDTNGFIIKAKQ 90
>Y018_MYCPN (P75095) Hypothetical ABC transporter ATP-binding protein MG014| homolog (D12_orf623) Length = 623 Score = 36.6 bits (83), Expect = 0.030 Identities = 29/101 (28%), Positives = 44/101 (43%), Gaps = 1/101 (0%) Frame = +2 Query: 89 TISMMIQTKVSLDRIASFLCLEELPTDAV-DRLPSGSSNVAIEVSNGCFSWDGSPELPTL 265 T+ +++V+L RI L E+ V D+ S +E N F L Sbjct: 327 TMVNFTRSRVALGRIKDVLNKPEIQQHVVPDQTVLAPS---LEFKNVAFGLGNKENRDFL 383 Query: 266 KDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEV 388 +DLNF+ + G + G GSGKS + + I G GE+ Sbjct: 384 QDLNFKFEAGKTYGIVGPTGSGKSLIANIIGGLYEPNQGEI 424
>MDL1_CANAL (P97998) ATP-dependent permease MDL1| Length = 685 Score = 36.6 bits (83), Expect = 0.030 Identities = 20/53 (37%), Positives = 27/53 (50%) Frame = +2 Query: 200 NVAIEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCIL 358 N IE F++ PE KDLN +QG V + G GSGKS++ +L Sbjct: 437 NGDIEFKGIDFTYPSRPESGIFKDLNLHIKQGENVCLVGPSGSGKSTVSQLLL 489
>YDDA_ECOLI (P31826) Inner membrane ABC transporter ATP-binding protein yddA| (CDS102) Length = 561 Score = 36.6 bits (83), Expect = 0.030 Identities = 20/60 (33%), Positives = 33/60 (55%) Frame = +2 Query: 263 LKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEVKTCGTMAYVSQTAWIQSG 442 L++LNF G + + G G+GK++LL + P G++ + YVSQT I++G Sbjct: 383 LENLNFHVSPGKWLLLKGYSGAGKTTLLKTLSHCWPWFKGDISSPADSWYVSQTPLIKTG 442
>MDR13_ARATH (Q9LHD1) Multidrug resistance protein 13 (P-glycoprotein 15)| Length = 1240 Score = 36.6 bits (83), Expect = 0.030 Identities = 31/122 (25%), Positives = 49/122 (40%), Gaps = 4/122 (3%) Frame = +2 Query: 47 TFRVLQEPIYNLPDTISMMIQTKVSLDRIASFLCLEELPTDAVDRLPSGSSNVAI----E 214 TF +L + D SM D + S + + T P G I E Sbjct: 937 TFMILVSTGRVIADAGSMTTDLAKGSDAVGSVFAVLDRYTSIDPEDPDGYETERITGQVE 996 Query: 215 VSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEVKT 394 + FS+ P++ K+ + + ++G A+ G GSGKS+++ I L G VK Sbjct: 997 FLDVDFSYPTRPDVIIFKNFSIKIEEGKSTAIVGPSGSGKSTIIGLIERFYDPLKGIVKI 1056 Query: 395 CG 400 G Sbjct: 1057 DG 1058 Score = 36.2 bits (82), Expect = 0.039 Identities = 22/77 (28%), Positives = 34/77 (44%) Frame = +2 Query: 209 IEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEV 388 +E N F + E D + G VA+ G GSGKS+++S + L+GE+ Sbjct: 359 VEFKNVKFVYPSRLETSIFDDFCLRVPSGKTVALVGGSGSGKSTVISLLQRFYDPLAGEI 418 Query: 389 KTCGTMAYVSQTAWIQS 439 G Q W++S Sbjct: 419 LIDGVSIDKLQVKWLRS 435
>MDR1_HUMAN (P08183) Multidrug resistance protein 1 (EC 3.6.3.44) (P-glycoprotein| 1) (CD243 antigen) Length = 1280 Score = 36.6 bits (83), Expect = 0.030 Identities = 17/70 (24%), Positives = 38/70 (54%) Frame = +2 Query: 230 FSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEVKTCGTMA 409 F++ P++P L+ L+ + ++G +A+ G+ G GKS+++ + L+G+V G Sbjct: 1042 FNYPTRPDIPVLQGLSLEVKKGQTLALVGSSGCGKSTVVQLLERFYDPLAGKVLLDGKEI 1101 Query: 410 YVSQTAWIQS 439 W+++ Sbjct: 1102 KRLNVQWLRA 1111 Score = 35.4 bits (80), Expect = 0.066 Identities = 18/44 (40%), Positives = 24/44 (54%) Frame = +2 Query: 209 IEVSNGCFSWDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSS 340 +E N FS+ E+ LK LN + Q G VA+ G G GKS+ Sbjct: 392 LEFRNVHFSYPSRKEVKILKGLNLKVQSGQTVALVGNSGCGKST 435
>SAPF_SHIFL (P0AAI0) Peptide transport system ATP-binding protein sapF| Length = 268 Score = 36.6 bits (83), Expect = 0.030 Identities = 17/51 (33%), Positives = 28/51 (54%) Frame = +2 Query: 236 WDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEV 388 W + +K L+F ++G +A+ G GSGKS+L + G + SGE+ Sbjct: 21 WFRRQTVEAVKPLSFTLREGQTLAIIGENGSGKSTLAKMLAGMIEPTSGEL 71
>SAPF_ECOLI (P0AAH8) Peptide transport system ATP-binding protein sapF| Length = 268 Score = 36.6 bits (83), Expect = 0.030 Identities = 17/51 (33%), Positives = 28/51 (54%) Frame = +2 Query: 236 WDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEV 388 W + +K L+F ++G +A+ G GSGKS+L + G + SGE+ Sbjct: 21 WFRRQTVEAVKPLSFTLREGQTLAIIGENGSGKSTLAKMLAGMIEPTSGEL 71
>SAPF_ECOL6 (P0AAH9) Peptide transport system ATP-binding protein sapF| Length = 268 Score = 36.6 bits (83), Expect = 0.030 Identities = 17/51 (33%), Positives = 28/51 (54%) Frame = +2 Query: 236 WDGSPELPTLKDLNFQAQQGMRVAVCGTVGSGKSSLLSCILGEVPKLSGEV 388 W + +K L+F ++G +A+ G GSGKS+L + G + SGE+ Sbjct: 21 WFRRQTVEAVKPLSFTLREGQTLAIIGENGSGKSTLAKMLAGMIEPTSGEL 71 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 69,820,534 Number of Sequences: 219361 Number of extensions: 1416694 Number of successful extensions: 5949 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 5577 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 5918 length of database: 80,573,946 effective HSP length: 102 effective length of database: 58,199,124 effective search space used: 2735358828 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
