>ACOC_CUCMA (P49608) Aconitate hydratase, cytoplasmic (EC 4.2.1.3) (Citrate|
           hydro-lyase) (Aconitase)
          Length = 898

 Score = 97.4 bits (241), Expect = 1e-20
 Identities = 44/55 (80%), Positives = 50/55 (90%)
 Frame = +2

Query: 278 EHAYSNILTSLPKPGGGEYGKFYSLPALNDPRIDKLPYSIRILLESAIRNCDGFQ 442
           E+ +   LTSLPKPGGGE+GK+YSLP+LNDPRID+LPYSIRILLESAIRNCD FQ
Sbjct: 4   ENPFKENLTSLPKPGGGEFGKYYSLPSLNDPRIDRLPYSIRILLESAIRNCDNFQ 58

>ACOC_ARATH (Q42560) Aconitate hydratase, cytoplasmic (EC 4.2.1.3) (Citrate|
           hydro-lyase) (Aconitase)
          Length = 898

 Score = 90.9 bits (224), Expect = 1e-18
 Identities = 42/56 (75%), Positives = 49/56 (87%)
 Frame = +2

Query: 275 TEHAYSNILTSLPKPGGGEYGKFYSLPALNDPRIDKLPYSIRILLESAIRNCDGFQ 442
           +E+ + +IL +L KP GGE+G +YSLPALNDPRIDKLPYSIRILLESAIRNCD FQ
Sbjct: 3   SENPFRSILKALEKPDGGEFGNYYSLPALNDPRIDKLPYSIRILLESAIRNCDEFQ 58

>IREB2_RAT (Q62751) Iron-responsive element-binding protein 2 (IRE-BP 2) (Iron|
           regulatory protein 2) (IRP2)
          Length = 963

 Score = 52.4 bits (124), Expect = 5e-07
 Identities = 22/39 (56%), Positives = 29/39 (74%)
 Frame = +2

Query: 323 GGEYGKFYSLPALNDPRIDKLPYSIRILLESAIRNCDGF 439
           G    KF+++P L   + D LPYSIR+LLE+A+RNCDGF
Sbjct: 19  GSSQKKFFNVPKLGGTKYDILPYSIRVLLEAAVRNCDGF 57

>IREB2_MOUSE (Q811J3) Iron-responsive element-binding protein 2 (IRE-BP 2) (Iron|
           regulatory protein 2) (IRP2)
          Length = 963

 Score = 52.4 bits (124), Expect = 5e-07
 Identities = 22/39 (56%), Positives = 29/39 (74%)
 Frame = +2

Query: 323 GGEYGKFYSLPALNDPRIDKLPYSIRILLESAIRNCDGF 439
           G    KF+++P L   + D LPYSIR+LLE+A+RNCDGF
Sbjct: 19  GNSQKKFFNVPKLGGTKYDILPYSIRVLLEAAVRNCDGF 57

>IREB1_HUMAN (P21399) Iron-responsive element-binding protein 1 (IRE-BP 1) (Iron|
           regulatory protein 1) (IRP1) (Ferritin repressor
           protein) (Aconitate hydratase) (EC 4.2.1.3) (Citrate
           hydro-lyase) (Aconitase)
          Length = 889

 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 21/34 (61%), Positives = 27/34 (79%)
 Frame = +2

Query: 338 KFYSLPALNDPRIDKLPYSIRILLESAIRNCDGF 439
           KF++L  L D R  +LP+SIR+LLE+AIRNCD F
Sbjct: 20  KFFNLNKLEDSRYGRLPFSIRVLLEAAIRNCDEF 53

>IREB1_RAT (Q63270) Iron-responsive element-binding protein 1 (IRE-BP 1) (Iron|
           regulatory protein 1) (IRP1) (Ferritin repressor
           protein) (Aconitate hydratase) (EC 4.2.1.3) (Citrate
           hydro-lyase) (Aconitase)
          Length = 889

 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 20/34 (58%), Positives = 27/34 (79%)
 Frame = +2

Query: 338 KFYSLPALNDPRIDKLPYSIRILLESAIRNCDGF 439
           KF++L  L D R  +LP+SIR+LLE+A+RNCD F
Sbjct: 20  KFFNLNKLEDSRYGRLPFSIRVLLEAAVRNCDEF 53

>IREB1_CHICK (Q90875) Iron-responsive element binding protein (IRE-BP) (Iron|
           regulatory protein) (IRP) (Ferritin repressor protein)
           (Aconitate hydratase) (EC 4.2.1.3) (Citrate hydro-lyase)
           (Aconitase)
          Length = 889

 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 21/34 (61%), Positives = 27/34 (79%)
 Frame = +2

Query: 338 KFYSLPALNDPRIDKLPYSIRILLESAIRNCDGF 439
           KF++L  L D R  +LP+SIR+LLE+AIRNCD F
Sbjct: 20  KFFNLSKLEDVRYARLPFSIRVLLEAAIRNCDEF 53

>IREB1_MOUSE (P28271) Iron-responsive element-binding protein 1 (IRE-BP 1) (Iron|
           regulatory protein 1) (IRP1) (Ferritin repressor
           protein) (Aconitate hydratase) (EC 4.2.1.3) (Citrate
           hydro-lyase) (Aconitase)
          Length = 889

 Score = 46.2 bits (108), Expect = 4e-05
 Identities = 19/34 (55%), Positives = 27/34 (79%)
 Frame = +2

Query: 338 KFYSLPALNDPRIDKLPYSIRILLESAIRNCDGF 439
           +F++L  L D R  +LP+SIR+LLE+A+RNCD F
Sbjct: 20  RFFNLNKLEDSRYGRLPFSIRVLLEAAVRNCDEF 53

>ACOC_CAEEL (Q23500) Probable aconitate hydratase, cytoplasmic (EC 4.2.1.3)|
           (Citrate hydro-lyase) (Aconitase)
          Length = 887

 Score = 45.1 bits (105), Expect = 8e-05
 Identities = 22/52 (42%), Positives = 35/52 (67%)
 Frame = +2

Query: 284 AYSNILTSLPKPGGGEYGKFYSLPALNDPRIDKLPYSIRILLESAIRNCDGF 439
           A++N++ +L    G    K++ L  LND R ++LP SI+ LLE+A+R+CD F
Sbjct: 2   AFNNLIRNLAI--GDNVYKYFDLNGLNDARYNELPISIKYLLEAAVRHCDEF 51

>IREB1_RABIT (Q01059) Iron-responsive element-binding protein 1 (IRE-BP 1) (Iron|
           regulatory protein 1) (IRP1) (Ferritin repressor
           protein) (Aconitate hydratase) (EC 4.2.1.3) (Citrate
           hydro-lyase) (Aconitase)
          Length = 889

 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 19/34 (55%), Positives = 27/34 (79%)
 Frame = +2

Query: 338 KFYSLPALNDPRIDKLPYSIRILLESAIRNCDGF 439
           KF++L  L+  R  +LP+SIR+LLE+A+RNCD F
Sbjct: 20  KFFNLNKLDYSRYGRLPFSIRVLLEAAVRNCDKF 53

>IREB2_HUMAN (P48200) Iron-responsive element-binding protein 2 (IRE-BP 2) (Iron|
           regulatory protein 2) (IRP2)
          Length = 963

 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 20/34 (58%), Positives = 26/34 (76%)
 Frame = +2

Query: 338 KFYSLPALNDPRIDKLPYSIRILLESAIRNCDGF 439
           KF+ +  L   + D LPYSIR+LLE+A+RNCDGF
Sbjct: 24  KFFDVSKLGT-KYDVLPYSIRVLLEAAVRNCDGF 56

>ACON_BACSU (P09339) Aconitate hydratase (EC 4.2.1.3) (Citrate hydro-lyase)|
           (Aconitase)
          Length = 908

 Score = 42.7 bits (99), Expect = 4e-04
 Identities = 21/41 (51%), Positives = 28/41 (68%), Gaps = 3/41 (7%)
 Frame = +2

Query: 326 GEYGKFYSLPALNDP---RIDKLPYSIRILLESAIRNCDGF 439
           G+   +YSL AL D    ++ KLPYSI++LLES +R  DGF
Sbjct: 22  GKTYHYYSLKALEDSGIGKVSKLPYSIKVLLESVLRQVDGF 62

>ACON_FRATH (Q2A1K3) Aconitate hydratase (EC 4.2.1.3) (Citrate hydro-lyase)|
           (Aconitase)
          Length = 937

 Score = 37.4 bits (85), Expect = 0.017
 Identities = 20/51 (39%), Positives = 30/51 (58%), Gaps = 3/51 (5%)
 Frame = +2

Query: 299 LTSLPKPGGGEYGKFYSLPALNDPR---IDKLPYSIRILLESAIRNCDGFQ 442
           +T L     G+    YSL  L+      + +LPYSIR+LLE+ +RN DG++
Sbjct: 7   ITKLQIEDKGKKYSLYSLKKLSQELGKDVTRLPYSIRVLLENQLRNIDGYK 57

>ACON_STAES (Q8CPC2) Aconitate hydratase (EC 4.2.1.3) (Citrate hydro-lyase)|
           (Aconitase)
          Length = 901

 Score = 36.2 bits (82), Expect = 0.038
 Identities = 19/41 (46%), Positives = 25/41 (60%), Gaps = 3/41 (7%)
 Frame = +2

Query: 326 GEYGKFYSLPALNDP---RIDKLPYSIRILLESAIRNCDGF 439
           G+   +Y L  L +    +I KLPYSIR+LLES +R  D F
Sbjct: 17  GQSYTYYDLQTLEEKGLAKISKLPYSIRVLLESVLRQEDDF 57

>ACON_STAEQ (Q5HPJ0) Aconitate hydratase (EC 4.2.1.3) (Citrate hydro-lyase)|
           (Aconitase)
          Length = 901

 Score = 36.2 bits (82), Expect = 0.038
 Identities = 19/41 (46%), Positives = 25/41 (60%), Gaps = 3/41 (7%)
 Frame = +2

Query: 326 GEYGKFYSLPALNDP---RIDKLPYSIRILLESAIRNCDGF 439
           G+   +Y L  L +    +I KLPYSIR+LLES +R  D F
Sbjct: 17  GQSYTYYDLQTLEEKGLAKISKLPYSIRVLLESVLRQEDDF 57

>ACON_STAAR (Q6GH55) Aconitate hydratase (EC 4.2.1.3) (Citrate hydro-lyase)|
           (Aconitase)
          Length = 901

 Score = 35.8 bits (81), Expect = 0.049
 Identities = 18/41 (43%), Positives = 26/41 (63%), Gaps = 3/41 (7%)
 Frame = +2

Query: 326 GEYGKFYSLPALNDP---RIDKLPYSIRILLESAIRNCDGF 439
           G+   +Y L A+ +    ++ KLPYSIR+LLES +R  D F
Sbjct: 17  GQSYTYYDLKAVEEQGITKVSKLPYSIRVLLESLLRQEDDF 57

>ACON_STAAW (P63434) Aconitate hydratase (EC 4.2.1.3) (Citrate hydro-lyase)|
           (Aconitase)
          Length = 901

 Score = 34.3 bits (77), Expect = 0.14
 Identities = 19/41 (46%), Positives = 25/41 (60%), Gaps = 3/41 (7%)
 Frame = +2

Query: 326 GEYGKFYSLPALNDPRIDK---LPYSIRILLESAIRNCDGF 439
           G+   +Y L A+ +  I K   LPYSIR+LLES +R  D F
Sbjct: 17  GQSYTYYDLKAVEEQGITKVSNLPYSIRVLLESLLRQEDDF 57

>ACON_STAAS (Q6G9K9) Aconitate hydratase (EC 4.2.1.3) (Citrate hydro-lyase)|
           (Aconitase)
          Length = 901

 Score = 34.3 bits (77), Expect = 0.14
 Identities = 19/41 (46%), Positives = 25/41 (60%), Gaps = 3/41 (7%)
 Frame = +2

Query: 326 GEYGKFYSLPALNDPRIDK---LPYSIRILLESAIRNCDGF 439
           G+   +Y L A+ +  I K   LPYSIR+LLES +R  D F
Sbjct: 17  GQSYTYYDLKAVEEQGITKVSNLPYSIRVLLESLLRQEDDF 57

>ACON_STAAN (P99148) Aconitate hydratase (EC 4.2.1.3) (Citrate hydro-lyase)|
           (Aconitase)
          Length = 901

 Score = 34.3 bits (77), Expect = 0.14
 Identities = 19/41 (46%), Positives = 25/41 (60%), Gaps = 3/41 (7%)
 Frame = +2

Query: 326 GEYGKFYSLPALNDPRIDK---LPYSIRILLESAIRNCDGF 439
           G+   +Y L A+ +  I K   LPYSIR+LLES +R  D F
Sbjct: 17  GQSYTYYDLKAVEEQGITKVSNLPYSIRVLLESLLRQEDDF 57

>ACON_STAAM (P63433) Aconitate hydratase (EC 4.2.1.3) (Citrate hydro-lyase)|
           (Aconitase)
          Length = 901

 Score = 34.3 bits (77), Expect = 0.14
 Identities = 19/41 (46%), Positives = 25/41 (60%), Gaps = 3/41 (7%)
 Frame = +2

Query: 326 GEYGKFYSLPALNDPRIDK---LPYSIRILLESAIRNCDGF 439
           G+   +Y L A+ +  I K   LPYSIR+LLES +R  D F
Sbjct: 17  GQSYTYYDLKAVEEQGITKVSNLPYSIRVLLESLLRQEDDF 57

>ACON_STAAC (Q5HG69) Aconitate hydratase (EC 4.2.1.3) (Citrate hydro-lyase)|
           (Aconitase)
          Length = 901

 Score = 34.3 bits (77), Expect = 0.14
 Identities = 19/41 (46%), Positives = 25/41 (60%), Gaps = 3/41 (7%)
 Frame = +2

Query: 326 GEYGKFYSLPALNDPRIDK---LPYSIRILLESAIRNCDGF 439
           G+   +Y L A+ +  I K   LPYSIR+LLES +R  D F
Sbjct: 17  GQSYTYYDLKAVEEQGITKVSNLPYSIRVLLESLLRQEDDF 57

>ACON_BRAJA (P70920) Aconitate hydratase (EC 4.2.1.3) (Citrate hydro-lyase)|
           (Aconitase)
          Length = 906

 Score = 34.3 bits (77), Expect = 0.14
 Identities = 17/35 (48%), Positives = 23/35 (65%), Gaps = 3/35 (8%)
 Frame = +2

Query: 341 FYSLPALND---PRIDKLPYSIRILLESAIRNCDG 436
           +YSLP         I KLPYS+++LLE+ +RN DG
Sbjct: 22  YYSLPTAEKNGLKGISKLPYSMKVLLENLLRNEDG 56

>ACON_MYCAV (O08451) Aconitate hydratase (EC 4.2.1.3) (Citrate hydro-lyase)|
           (Aconitase)
          Length = 961

 Score = 33.1 bits (74), Expect = 0.32
 Identities = 16/38 (42%), Positives = 25/38 (65%)
 Frame = +2

Query: 323 GGEYGKFYSLPALNDPRIDKLPYSIRILLESAIRNCDG 436
           G +  + Y L A+  P  +KLPYS+++L E+ +RN DG
Sbjct: 44  GDKSYQIYRLDAV--PNTEKLPYSLKVLAENLLRNEDG 79

>ACON_CORJK (Q4JVM4) Aconitate hydratase (EC 4.2.1.3)|
          Length = 936

 Score = 31.6 bits (70), Expect = 0.93
 Identities = 14/32 (43%), Positives = 25/32 (78%)
 Frame = +2

Query: 341 FYSLPALNDPRIDKLPYSIRILLESAIRNCDG 436
           +++L A+  P ++KLPYS+++L E+ +RN DG
Sbjct: 23  YFALDAV--PGMEKLPYSLKVLGENLLRNEDG 52

>ACON_COREF (Q8FTA8) Aconitate hydratase (EC 4.2.1.3)|
          Length = 937

 Score = 30.8 bits (68), Expect = 1.6
 Identities = 14/32 (43%), Positives = 24/32 (75%)
 Frame = +2

Query: 341 FYSLPALNDPRIDKLPYSIRILLESAIRNCDG 436
           +Y+L A+  P ++KLPYS+++L E+ +R  DG
Sbjct: 23  YYALSAV--PGMEKLPYSLKVLGENLLRTEDG 52

>ACON_STRMU (Q59938) Aconitate hydratase (EC 4.2.1.3) (Citrate hydro-lyase)|
           (Aconitase)
          Length = 888

 Score = 30.0 bits (66), Expect = 2.7
 Identities = 13/23 (56%), Positives = 17/23 (73%)
 Frame = +2

Query: 365 DPRIDKLPYSIRILLESAIRNCD 433
           D  +D LPY+I+ILLES +R  D
Sbjct: 28  DIELDSLPYTIKILLESLLRKHD 50

>UBP30_HUMAN (Q70CQ3) Ubiquitin carboxyl-terminal hydrolase 30 (EC 3.1.2.15)|
           (Ubiquitin thioesterase 30)
           (Ubiquitin-specific-processing protease 30)
           (Deubiquitinating enzyme 30)
          Length = 517

 Score = 30.0 bits (66), Expect = 2.7
 Identities = 13/26 (50%), Positives = 20/26 (76%)
 Frame = +3

Query: 312 LSPGVVNMGNSTAFLH*MIQGSISCP 389
           L PG+VN+GN T F++ ++QG  +CP
Sbjct: 66  LVPGLVNLGN-TCFMNSLLQGLSACP 90

>ACON_CORGL (Q8NQ98) Aconitate hydratase (EC 4.2.1.3)|
          Length = 939

 Score = 29.3 bits (64), Expect = 4.6
 Identities = 13/32 (40%), Positives = 24/32 (75%)
 Frame = +2

Query: 341 FYSLPALNDPRIDKLPYSIRILLESAIRNCDG 436
           +++L A+  P ++KLPYS+++L E+ +R  DG
Sbjct: 23  YFALSAV--PGMEKLPYSLKVLGENLLRTEDG 52

>ACON_LEGPH (P37032) Aconitate hydratase (EC 4.2.1.3) (Citrate hydro-lyase)|
           (Aconitase) (Major iron-containing protein) (MICP)
           (IP210)
          Length = 891

 Score = 29.3 bits (64), Expect = 4.6
 Identities = 15/40 (37%), Positives = 25/40 (62%), Gaps = 3/40 (7%)
 Frame = +2

Query: 326 GEYGKFYSLPALNDPR---IDKLPYSIRILLESAIRNCDG 436
           G+   +YSL    +     I++LPYS+++LLE+ +R  DG
Sbjct: 18  GKTYNYYSLKEAENKHFKGINRLPYSLKVLLENLLRFEDG 57

>HYIN1_BRAJA (P59385) Indoleacetamide hydrolase (EC 3.5.1.-) (IAH)|
           (Indole-3-acetamide hydrolase)
          Length = 524

 Score = 28.9 bits (63), Expect = 6.0
 Identities = 12/32 (37%), Positives = 17/32 (53%)
 Frame = -1

Query: 386 AAYRSLDHLVQEGCRISHIHHPRA*GGWSKYC 291
           A  R+ DHL + G R+S +  P   G W  +C
Sbjct: 334 ALRRAADHLERSGYRVSEVEVPDINGVWQTWC 365


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 37,459,105
Number of Sequences: 219361
Number of extensions: 590374
Number of successful extensions: 1185
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1166
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 1185
length of database: 80,573,946
effective HSP length: 102
effective length of database: 58,199,124
effective search space used: 2677159704
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)