>TNPO3_MOUSE (Q6P2B1) Transportin 3|
          Length = 923

 Score = 66.6 bits (161), Expect = 2e-11
 Identities = 33/97 (34%), Positives = 57/97 (58%)
 Frame = +1

Query: 124 VKEALAALYHHPDDTTRTAADRWLQKFQHTLDAWQVADSLLHDESSNLETLMFCSQTLRS 303
           V +A+ ALYH PD + +  A  WL + Q ++ AW+++D LL     ++E+  F +QT++ 
Sbjct: 11  VYQAVQALYHDPDPSGKERASFWLGELQRSVHAWEISDQLLQIR-QDVESCYFAAQTMKM 69

Query: 304 KVQRDFEELPSEAFRPLQDSLYGLLKKFNKGPPKVRT 414
           K+Q  F ELP+++   L+DSL   ++      P + T
Sbjct: 70  KIQTSFYELPTDSHASLRDSLLTHIQNLKDLSPVIVT 106

>TNPO3_HUMAN (Q9Y5L0) Transportin 3 (Transportin-SR) (TRN-SR) (Importin 12)|
          Length = 975

 Score = 66.6 bits (161), Expect = 2e-11
 Identities = 33/97 (34%), Positives = 57/97 (58%)
 Frame = +1

Query: 124 VKEALAALYHHPDDTTRTAADRWLQKFQHTLDAWQVADSLLHDESSNLETLMFCSQTLRS 303
           V +A+ ALYH PD + +  A  WL + Q ++ AW+++D LL     ++E+  F +QT++ 
Sbjct: 11  VYQAVQALYHDPDPSGKERASFWLGELQRSVHAWEISDQLLQIR-QDVESCYFAAQTMKM 69

Query: 304 KVQRDFEELPSEAFRPLQDSLYGLLKKFNKGPPKVRT 414
           K+Q  F ELP+++   L+DSL   ++      P + T
Sbjct: 70  KIQTSFYELPTDSHASLRDSLLTHIQNLKDLSPVIVT 106

>YNR7_SCHPO (Q9USZ2) Hypothetical protein C11G11.07 in chromosome II|
          Length = 955

 Score = 65.9 bits (159), Expect = 4e-11
 Identities = 33/93 (35%), Positives = 53/93 (56%)
 Frame = +1

Query: 121 TVKEALAALYHHPDDTTRTAADRWLQKFQHTLDAWQVADSLLHDESSNLETLMFCSQTLR 300
           T+  ALA LY + D   +  A+ +L++FQ +  AWQ+  S+L+ + S++E  +F +QTLR
Sbjct: 3   TLLSALATLYANTDREQKLQANNYLEEFQKSPAAWQICFSILNQDDSSIEAKLFAAQTLR 62

Query: 301 SKVQRDFEELPSEAFRPLQDSLYGLLKKFNKGP 399
            K+  DF +LP E     ++SL  L       P
Sbjct: 63  QKIVYDFHQLPKETHIEFRNSLLQLFLAAKDSP 95

>IPO13_MOUSE (Q8K0C1) Importin-13 (Imp13)|
          Length = 963

 Score = 46.2 bits (108), Expect = 3e-05
 Identities = 31/118 (26%), Positives = 55/118 (46%), Gaps = 4/118 (3%)
 Frame = +1

Query: 73  EEEVGFGADMEAQA----TATVKEALAALYHHPDDTTRTAADRWLQKFQHTLDAWQVADS 240
           EE++G      A A       V++AL  LY+ P+   +  A +WL + Q +  AW  +  
Sbjct: 5   EEQLGAAGAGAAPALDFTVENVEKALHQLYYDPNIDNKNLAQKWLMQAQVSPQAWHFSWQ 64

Query: 241 LLHDESSNLETLMFCSQTLRSKVQRDFEELPSEAFRPLQDSLYGLLKKFNKGPPKVRT 414
           LL  +    E   F +  L  K+ R + ++P++ +  L+  L+  + +F  G   V T
Sbjct: 65  LLQPDKVP-EIQYFGASALHIKISRYWSDIPTDQYESLKAQLFTQITRFASGSKIVLT 121

>IPO13_HUMAN (O94829) Importin-13 (Imp13) (Ran-binding protein 13) (RanBP13)|
           (Karyopherin 13) (Kap13)
          Length = 963

 Score = 45.4 bits (106), Expect = 5e-05
 Identities = 26/97 (26%), Positives = 48/97 (49%)
 Frame = +1

Query: 124 VKEALAALYHHPDDTTRTAADRWLQKFQHTLDAWQVADSLLHDESSNLETLMFCSQTLRS 303
           V++AL  LY+ P+   +  A +WL + Q +  AW  +  LL  +    E   F +  L  
Sbjct: 26  VEKALHQLYYDPNIENKNLAQKWLMQAQVSPQAWHFSWQLLQPDKVP-EIQYFGASALHI 84

Query: 304 KVQRDFEELPSEAFRPLQDSLYGLLKKFNKGPPKVRT 414
           K+ R + ++P++ +  L+  L+  + +F  G   V T
Sbjct: 85  KISRYWSDIPTDQYESLKAQLFTQITRFASGSKIVLT 121

>IPO13_RAT (Q9JM04) Importin-13 (Imp13) (Late gestation lung 2 protein)|
          Length = 963

 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 30/118 (25%), Positives = 54/118 (45%), Gaps = 4/118 (3%)
 Frame = +1

Query: 73  EEEVGFGADMEAQA----TATVKEALAALYHHPDDTTRTAADRWLQKFQHTLDAWQVADS 240
           EE++G      A A       V++AL  LY+ P+   +  A +WL + Q +  AW  +  
Sbjct: 5   EEQLGAAGAGAAPALDFTVENVEKALHQLYYDPNIENKNLAQKWLMQAQVSPQAWHFSWQ 64

Query: 241 LLHDESSNLETLMFCSQTLRSKVQRDFEELPSEAFRPLQDSLYGLLKKFNKGPPKVRT 414
           LL  +    E   F +  L  K+ R + ++P++ +  L+   +  + +F  G   V T
Sbjct: 65  LLQPDKVP-EIQYFGASALHIKISRYWSDIPTDQYESLKAHSFTQITRFASGSKIVLT 121

>MTR10_YEAST (Q99189) mRNA transport regulator MTR10|
          Length = 972

 Score = 42.0 bits (97), Expect = 6e-04
 Identities = 28/101 (27%), Positives = 51/101 (50%), Gaps = 3/101 (2%)
 Frame = +1

Query: 100 MEAQATATVKEALAALYHHPDDTTRTAADRWLQKFQHTLDAWQVADSLLHDE---SSNLE 270
           M+    + ++ AL  +        +  A ++L++FQ +  AW + + +L  E   ++ LE
Sbjct: 1   MDNLQVSDIETALQCISSTASQDDKNKALQFLEQFQRSTVAWSICNEILSKEDPTNALLE 60

Query: 271 TLMFCSQTLRSKVQRDFEELPSEAFRPLQDSLYGLLKKFNK 393
             +F +QTLR+KV  D  +L +      +DSL  LL   N+
Sbjct: 61  LNIFAAQTLRNKVTYDLSQLENN-LPQFKDSLLTLLLSHNQ 100

>SORL_RABIT (Q95209) Sortilin-related receptor precursor (Sorting|
           protein-related receptor containing LDLR class A
           repeats) (SorLA) (SorLA-1) (Low-density lipoprotein
           receptor relative with 11 ligand-binding repeats) (LDLR
           relative with 11 ligand-binding
          Length = 2213

 Score = 33.1 bits (74), Expect = 0.27
 Identities = 28/96 (29%), Positives = 40/96 (41%), Gaps = 11/96 (11%)
 Frame = +1

Query: 13  PRKSSTVEGYSRKRAAGGSVEEEVGFGADMEAQATATVKEALAALYHHPDDTTRTA-ADR 189
           PR S     Y   ++    + E++ FGA    +A       +A  YH P D  R   AD 
Sbjct: 130 PRSSDVYVSYDYGKSFN-KISEKLNFGAGNNTEAV------VAQFYHSPADNKRYIFADA 182

Query: 190 WLQKFQHTLD----------AWQVADSLLHDESSNL 267
           + Q    T D           ++ AD LLH ++SNL
Sbjct: 183 YAQYLWITFDFCNTIHGFSIPFRAADLLLHSKASNL 218

>XPO1_YEAST (P30822) Exportin-1 (Chromosome region maintenance protein 1)|
          Length = 1084

 Score = 31.6 bits (70), Expect = 0.78
 Identities = 19/83 (22%), Positives = 40/83 (48%)
 Frame = +1

Query: 130 EALAALYHHPDDTTRTAADRWLQKFQHTLDAWQVADSLLHDESSNLETLMFCSQTLRSKV 309
           + + + ++      +  A   L KFQ   DAWQ AD +L   S+N ++       L   +
Sbjct: 17  DQVVSTFYQGSGVQQKQAQEILTKFQDNPDAWQKADQIL-QFSTNPQSKFIALSILDKLI 75

Query: 310 QRDFEELPSEAFRPLQDSLYGLL 378
            R ++ LP++    +++ + G++
Sbjct: 76  TRKWKLLPNDHRIGIRNFVVGMI 98

>HPPD_TETTH (Q27203) 4-hydroxyphenylpyruvate dioxygenase (EC 1.13.11.27)|
           (4HPPD) (HPD) (HPPDase) (4-hydroxyphenylpyruvic acid
           oxidase) (F-antigen homolog) (TF-AG)
          Length = 404

 Score = 31.2 bits (69), Expect = 1.0
 Identities = 16/53 (30%), Positives = 28/53 (52%)
 Frame = +1

Query: 151 HHPDDTTRTAADRWLQKFQHTLDAWQVADSLLHDESSNLETLMFCSQTLRSKV 309
           + PD+   +AAD W +K       W V DS++H E S+L +++      + K+
Sbjct: 201 NQPDNMMTSAAD-WYEKTLDFHRFWSVDDSMIHTEFSSLRSIVMTDYDQKIKM 252

>MURA_BORPE (Q7VSZ3) UDP-N-acetylglucosamine 1-carboxyvinyltransferase (EC|
           2.5.1.7) (Enoylpyruvate transferase)
           (UDP-N-acetylglucosamine enolpyruvyl transferase) (EPT)
          Length = 422

 Score = 29.6 bits (65), Expect = 2.9
 Identities = 20/59 (33%), Positives = 25/59 (42%), Gaps = 10/59 (16%)
 Frame = +1

Query: 40  YSRKRAAGGSVEEEVGFGADMEAQATA--TVKEALAAL--------YHHPDDTTRTAAD 186
           + R RA G    E  GF  DM+AQ  A  TV +  A +        Y H  +  R  AD
Sbjct: 286 HGRPRAVGARTHEYPGFATDMQAQLMALDTVADGTAVIVENIFENRYMHVQELCRLGAD 344

>MURA_BORBR (Q7WDY6) UDP-N-acetylglucosamine 1-carboxyvinyltransferase (EC|
           2.5.1.7) (Enoylpyruvate transferase)
           (UDP-N-acetylglucosamine enolpyruvyl transferase) (EPT)
          Length = 422

 Score = 29.6 bits (65), Expect = 2.9
 Identities = 20/59 (33%), Positives = 25/59 (42%), Gaps = 10/59 (16%)
 Frame = +1

Query: 40  YSRKRAAGGSVEEEVGFGADMEAQATA--TVKEALAAL--------YHHPDDTTRTAAD 186
           + R RA G    E  GF  DM+AQ  A  TV +  A +        Y H  +  R  AD
Sbjct: 286 HGRPRAVGARTHEYPGFATDMQAQLMALDTVADGTAVIVENIFENRYMHVQELCRLGAD 344

>SORL_HUMAN (Q92673) Sortilin-related receptor precursor (Sorting|
           protein-related receptor containing LDLR class A
           repeats) (SorLA) (SorLA-1) (Low-density lipoprotein
           receptor relative with 11 ligand-binding repeats) (LDLR
           relative with 11 ligand-binding
          Length = 2214

 Score = 28.9 bits (63), Expect = 5.0
 Identities = 22/77 (28%), Positives = 34/77 (44%), Gaps = 11/77 (14%)
 Frame = +1

Query: 70  VEEEVGFGADMEAQATATVKEALAALYHHPDDTTRTA-ADRWLQKFQHTLD--------- 219
           + +++ FG    ++A       +A  YH P D  R   AD + Q    T D         
Sbjct: 148 ISDKLNFGLGNRSEAV------IAQFYHSPADNKRYIFADAYAQYLWITFDFCNTLQGFS 201

Query: 220 -AWQVADSLLHDESSNL 267
             ++ AD LLH ++SNL
Sbjct: 202 IPFRAADLLLHSKASNL 218

>ESYN_FUSEQ (Q00869) Enniatin synthetase [Includes: N-methylcyclopeptide|
            synthetase (EC 6.3.2.-);
            S-adenosyl-L-methionine-dependent N-methyltransferase (EC
            2.1.1.-)]
          Length = 3131

 Score = 28.9 bits (63), Expect = 5.0
 Identities = 23/75 (30%), Positives = 32/75 (42%), Gaps = 17/75 (22%)
 Frame = +1

Query: 70   VEEEVGFGADMEAQATATVKEALAALYHH--PDDTTR---------------TAADRWLQ 198
            + +E GF  ++ A    +   AL A++HH  P  T R               T A+R LQ
Sbjct: 2379 IAKEAGFRVEVSAARQWSQSGALDAVFHHFPPSSTDRTLIQFPTDNELRSSLTLANRPLQ 2438

Query: 199  KFQHTLDAWQVADSL 243
            K Q    A QV + L
Sbjct: 2439 KLQRRRAALQVREKL 2453

>CHSC_ASPFU (Q92197) Chitin synthase C (EC 2.4.1.16) (Chitin-UDP|
           acetyl-glucosaminyl transferase C) (Class-III chitin
           synthase C)
          Length = 893

 Score = 28.9 bits (63), Expect = 5.0
 Identities = 23/79 (29%), Positives = 38/79 (48%), Gaps = 3/79 (3%)
 Frame = +1

Query: 19  KSSTVEGYSRKRAAGGS---VEEEVGFGADMEAQATATVKEALAALYHHPDDTTRTAADR 189
           K+  +     K+A G     +EE     AD+++Q  ATVK ALA  Y  P + +  + D 
Sbjct: 755 KADALPSAQTKKADGSKSNFIEEIDKPQADIDSQFEATVKRALAP-YQEPKEDSTISLDD 813

Query: 190 WLQKFQHTLDAWQVADSLL 246
             + F+ +L    +  +LL
Sbjct: 814 SYRNFRTSLVLLWILSNLL 832

>DYHC_FUSSO (P78716) Dynein heavy chain, cytosolic (DYHC)|
          Length = 4349

 Score = 28.5 bits (62), Expect = 6.6
 Identities = 28/133 (21%), Positives = 51/133 (38%), Gaps = 18/133 (13%)
 Frame = +1

Query: 1    RSSTPRKSSTVEGYSRKRAAGGSVEEEVGFGADMEAQATATVKEALAALYH--------- 153
            R +  RK++++E  +        V        +  A+A   V+EA A++ +         
Sbjct: 3257 REAEQRKNTSLEIQANLEKQEAEVASRKKVVLEDLAKAEPAVEEAKASVSNIKRQHLTEV 3316

Query: 154  ----HPDDTTRTAADRWLQKFQHTLDAWQVADSLLHDESSNLETLMF-----CSQTLRSK 306
                +P    R A D       H ++ W+    +L  +      LMF      ++ LR+K
Sbjct: 3317 RSMGNPPQGVRLAMDAVCTLLGHRINDWKAVQGILRKDDFIASILMFDNAKQMTKGLRNK 3376

Query: 307  VQRDFEELPSEAF 345
            ++ DF   P   F
Sbjct: 3377 MRNDFLSNPEFTF 3389

>ESYN_GIBPU (Q00868) Enniatin synthetase [Includes: N-methylcyclopeptide|
           synthetase (EC 6.3.2.-);
           S-adenosyl-L-methionine-dependent N-methyltransferase
           (EC 2.1.1.-)] (Fragment)
          Length = 983

 Score = 28.5 bits (62), Expect = 6.6
 Identities = 23/75 (30%), Positives = 33/75 (44%), Gaps = 17/75 (22%)
 Frame = +1

Query: 70  VEEEVGFGADMEAQATATVKEALAALYHH-------------PDD----TTRTAADRWLQ 198
           +  E GF  ++ A    +   AL A++HH             P D    ++ T A+R LQ
Sbjct: 756 IANEAGFRVEVSAARQWSQNGALDAVFHHFPSSNTDRTLIQFPTDNQLRSSLTLANRPLQ 815

Query: 199 KFQHTLDAWQVADSL 243
           K Q    A QV +SL
Sbjct: 816 KLQRRRAALQVRESL 830

>SORL_MOUSE (O88307) Sortilin-related receptor precursor (Sorting|
           protein-related receptor containing LDLR class A
           repeats) (mSorLA) (SorLA-1) (Low-density lipoprotein
           receptor relative with 11 ligand-binding repeats) (LDLR
           relative with 11 ligand-binding
          Length = 2215

 Score = 28.5 bits (62), Expect = 6.6
 Identities = 24/96 (25%), Positives = 39/96 (40%), Gaps = 11/96 (11%)
 Frame = +1

Query: 13  PRKSSTVEGYSRKRAAGGSVEEEVGFGADMEAQATATVKEALAALYHHPDDTTRTA-ADR 189
           P+ S     Y   ++    + E++ FG    ++A       ++  YH P D  R    D 
Sbjct: 130 PKSSDVYVSYDYGKSFS-KISEKLNFGVGNNSEAV------ISQFYHSPADNKRYIFVDA 182

Query: 190 WLQKFQHTLD----------AWQVADSLLHDESSNL 267
           + Q    T D           ++ AD LLH ++SNL
Sbjct: 183 YAQYLWITFDFCSTIHGFSIPFRAADLLLHSKASNL 218

>K1H1_HUMAN (Q15323) Keratin, type I cuticular Ha1 (Hair keratin, type I Ha1)|
          Length = 416

 Score = 28.1 bits (61), Expect = 8.6
 Identities = 17/56 (30%), Positives = 27/56 (48%)
 Frame = +1

Query: 163 DTTRTAADRWLQKFQHTLDAWQVADSLLHDESSNLETLMFCSQTLRSKVQRDFEEL 330
           D  + AAD +  K+Q  L    V +S ++     L+ L  C   L ++V+   EEL
Sbjct: 132 DNAKLAADDFRTKYQTELSLRHVVESDINGLRRILDELTLCKSDLEAQVESLKEEL 187

>CHS3_EXODE (P30602) Chitin synthase 3 (EC 2.4.1.16) (Chitin-UDP|
            acetyl-glucosaminyl transferase 3) (Class-III chitin
            synthase 3)
          Length = 885

 Score = 28.1 bits (61), Expect = 8.6
 Identities = 26/80 (32%), Positives = 41/80 (51%), Gaps = 3/80 (3%)
 Frame = +1

Query: 70   VEEEVGFGADMEAQATATVKEALAALYHHPDDTTRTAADRWLQKFQHTLDA-WQVADSLL 246
            VEE     AD+++Q  ATV+ ALA  Y  P++      +   + F+  L A W  +++LL
Sbjct: 790  VEEVDKPQADIDSQFEATVRRALAP-YKPPEEKEEKTLEDSYKNFRTRLVATWIFSNALL 848

Query: 247  --HDESSNLETLMFCSQTLR 300
                 S +L+   F S+ LR
Sbjct: 849  AVAITSDSLDRFGFTSEPLR 868

>SYI_CHLTE (Q8KFL5) Isoleucyl-tRNA synthetase (EC 6.1.1.5) (Isoleucine--tRNA|
           ligase) (IleRS)
          Length = 1084

 Score = 28.1 bits (61), Expect = 8.6
 Identities = 28/119 (23%), Positives = 54/119 (45%), Gaps = 15/119 (12%)
 Frame = +1

Query: 28  TVEGYSRKRAAGG---------SVEEEVGFGADMEAQATATV---KEALAALYHHPDDTT 171
           T++GY   R AG          SVE+++G       +        +EA A +YHH DD  
Sbjct: 76  TMQGYQVPRKAGWDTHGLPVEISVEKKLGLKNKSHVEEYGVGEFNREARALVYHHIDDN- 134

Query: 172 RTAADRWLQKFQHTLDAWQVADS-LLHDESSNLETLMFCSQTLRSK--VQRDFEELPSE 339
               + W  K    +  W   DS  +  +++ +E++ +  +T+  K  + +D++ +P +
Sbjct: 135 ---REGW-GKLTERMGYWVDMDSPYITCDNNYIESVWWALKTIFDKGLIYKDYKIVPQD 189


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.313    0.127    0.364 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 43,321,596
Number of Sequences: 219361
Number of extensions: 647827
Number of successful extensions: 1907
Number of sequences better than 10.0: 21
Number of HSP's better than 10.0 without gapping: 1784
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 1905
length of database: 80,573,946
effective HSP length: 100
effective length of database: 58,637,846
effective search space used: 2228238148
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)