>COPB_RAT (P23514) Coatomer subunit beta (Beta-coat protein) (Beta-COP)|
          Length = 953

 Score = 92.0 bits (227), Expect = 7e-19
 Identities = 45/100 (45%), Positives = 68/100 (68%), Gaps = 1/100 (1%)
 Frame = +3

Query: 162 AMDKPCTLLVHFDKGSAAMAN-EIKADLEGSDVAAKVEAMKRAVMLLLNGETLPTLFITV 338
           A +  C  L++    S   +   +K DLE  DV +K EA+K+ ++++LNGE LP L +T+
Sbjct: 3   AAENVCYTLINVPMDSEPPSEISLKNDLEKGDVKSKTEALKKVIIMILNGEKLPGLLMTI 62

Query: 339 VRYVLPSEDHTIQKLLLLYLEIIDKRDAAGRVLPEMILIC 458
           +R+VLP +DHTI+KLLL++ EI+ K    GR+L EMIL+C
Sbjct: 63  IRFVLPLQDHTIKKLLLVFWEIVPKTTPDGRLLHEMILVC 102

>COPB_MOUSE (Q9JIF7) Coatomer subunit beta (Beta-coat protein) (Beta-COP)|
          Length = 953

 Score = 92.0 bits (227), Expect = 7e-19
 Identities = 45/100 (45%), Positives = 68/100 (68%), Gaps = 1/100 (1%)
 Frame = +3

Query: 162 AMDKPCTLLVHFDKGSAAMAN-EIKADLEGSDVAAKVEAMKRAVMLLLNGETLPTLFITV 338
           A +  C  L++    S   +   +K DLE  DV +K EA+K+ ++++LNGE LP L +T+
Sbjct: 3   AAENVCYTLINVPMDSEPPSEISLKNDLEKGDVKSKTEALKKVIIMILNGEKLPGLLMTI 62

Query: 339 VRYVLPSEDHTIQKLLLLYLEIIDKRDAAGRVLPEMILIC 458
           +R+VLP +DHTI+KLLL++ EI+ K    GR+L EMIL+C
Sbjct: 63  IRFVLPLQDHTIKKLLLVFWEIVPKTTPDGRLLHEMILVC 102

>COPB_HUMAN (P53618) Coatomer subunit beta (Beta-coat protein) (Beta-COP)|
          Length = 953

 Score = 92.0 bits (227), Expect = 7e-19
 Identities = 45/100 (45%), Positives = 68/100 (68%), Gaps = 1/100 (1%)
 Frame = +3

Query: 162 AMDKPCTLLVHFDKGSAAMAN-EIKADLEGSDVAAKVEAMKRAVMLLLNGETLPTLFITV 338
           A +  C  L++    S   +   +K DLE  DV +K EA+K+ ++++LNGE LP L +T+
Sbjct: 3   AAENVCYTLINVPMDSEPPSEISLKNDLEKGDVKSKTEALKKVIIMILNGEKLPGLLMTI 62

Query: 339 VRYVLPSEDHTIQKLLLLYLEIIDKRDAAGRVLPEMILIC 458
           +R+VLP +DHTI+KLLL++ EI+ K    GR+L EMIL+C
Sbjct: 63  IRFVLPLQDHTIKKLLLVFWEIVPKTTPDGRLLHEMILVC 102

>COPB_DROME (P45437) Coatomer subunit beta (Beta-coat protein) (Beta-COP)|
          Length = 964

 Score = 92.0 bits (227), Expect = 7e-19
 Identities = 42/95 (44%), Positives = 63/95 (66%)
 Frame = +3

Query: 174 PCTLLVHFDKGSAAMANEIKADLEGSDVAAKVEAMKRAVMLLLNGETLPTLFITVVRYVL 353
           PC  +++          ++K DLE  D   K+E +KR + LLLNGE  P L +T++R+VL
Sbjct: 6   PCYTIINSPDLEVTNEMQLKRDLEKGDTNVKIETLKRVIKLLLNGERYPGLIMTIIRFVL 65

Query: 354 PSEDHTIQKLLLLYLEIIDKRDAAGRVLPEMILIC 458
           P ++HTI+KLLL++ EI+ K  A G++L EMIL+C
Sbjct: 66  PVQNHTIKKLLLIFWEIVPKTSADGKLLQEMILVC 100

>COPB_SCHPO (Q9UUF7) Coatomer subunit beta (Beta-coat protein) (Beta-COP)|
          Length = 940

 Score = 66.6 bits (161), Expect = 3e-11
 Identities = 33/94 (35%), Positives = 55/94 (58%)
 Frame = +3

Query: 177 CTLLVHFDKGSAAMANEIKADLEGSDVAAKVEAMKRAVMLLLNGETLPTLFITVVRYVLP 356
           C  LV  D   A   + +K  LE  +   K+ AMK  + +++NG++LP++ + V+R+V+P
Sbjct: 3   CWTLVQQDFLEAPSVDALKTSLESKNDYVKISAMKTILRVVINGDSLPSILMHVIRFVMP 62

Query: 357 SEDHTIQKLLLLYLEIIDKRDAAGRVLPEMILIC 458
           S +  ++KLL  Y E+  K +  G +  EMIL C
Sbjct: 63  SRNKELKKLLYYYWEVCPKYNNDGTMKQEMILAC 96

>COPB_YEAST (P41810) Coatomer subunit beta (Beta-coat protein) (Beta-COP)|
          Length = 973

 Score = 58.9 bits (141), Expect = 6e-09
 Identities = 29/76 (38%), Positives = 49/76 (64%)
 Frame = +3

Query: 231 KADLEGSDVAAKVEAMKRAVMLLLNGETLPTLFITVVRYVLPSEDHTIQKLLLLYLEIID 410
           KA  +GSD   K++ MK  ++ +L G  +P L + ++R+V+PS++  ++KLL  Y EI+ 
Sbjct: 30  KALEKGSD-EQKIDTMKSILVTMLEGNPMPELLMHIIRFVMPSKNKELKKLLYFYWEIVP 88

Query: 411 KRDAAGRVLPEMILIC 458
           K    G++  EMIL+C
Sbjct: 89  KLAEDGKLRHEMILVC 104

>ABTAP_MOUSE (Q3V1V3) ABT1-associated protein|
          Length = 845

 Score = 40.4 bits (93), Expect = 0.002
 Identities = 22/58 (37%), Positives = 31/58 (53%)
 Frame = -2

Query: 467 GDLADEDHLREDAASGIALVNDLEVEEQQLLDGVVLGGEDVANDGDEERRQGLAIEEE 294
           G + DED L ED+ S   L +D E E++ + DG     ED + + DEE  +    EEE
Sbjct: 226 GKMPDEDALEEDSDSASELGSDEESEDEIISDGKTSADEDESEEEDEEEEEDSEEEEE 283

>SM1L2_HUMAN (Q8NDV3) Structural maintenance of chromosome 1-like 2 protein|
            (SMC1beta protein)
          Length = 1235

 Score = 32.7 bits (73), Expect = 0.47
 Identities = 20/57 (35%), Positives = 32/57 (56%), Gaps = 3/57 (5%)
 Frame = -2

Query: 455  DEDHLREDAASGIALVNDLEVEEQQLLDGVVL---GGEDVANDGDEERRQGLAIEEE 294
            D DHL++   + +  VN+L  ++QQL D  V      E V    +EER++ LA++ E
Sbjct: 848  DIDHLKKAEENCLQTVNELMAKQQQLKDIRVTQNSSAEKVQTQIEEERKKFLAVDRE 904

>MAM1_SCHPO (P78966) Mating factor M secretion protein mam1 (Multiple drug|
            resistance protein homolog) (P-glycoprotein)
          Length = 1336

 Score = 31.2 bits (69), Expect = 1.4
 Identities = 21/77 (27%), Positives = 40/77 (51%)
 Frame = +3

Query: 135  PARVHGRSGAMDKPCTLLVHFDKGSAAMANEIKADLEGSDVAAKVEAMKRAVMLLLNGET 314
            P  +H +SG +  P    + FD  S A  +  +  L  ++V+  +EA ++  ++ ++G  
Sbjct: 1082 PGNLH-KSGYLKFPLVGKIEFDGVSFAYPDSERNHLALNNVSLSIEAREKVAIVGISGSG 1140

Query: 315  LPTLFITVVRYVLPSED 365
              TL + ++R   PSED
Sbjct: 1141 KSTL-VELLRKTYPSED 1156

>DAB1_MACFA (Q9BGX5) Disabled homolog 1|
          Length = 555

 Score = 31.2 bits (69), Expect = 1.4
 Identities = 16/30 (53%), Positives = 18/30 (60%), Gaps = 6/30 (20%)
 Frame = +1

Query: 43  PVNHSPPLPAPRSRSTS------AADPTTD 114
           P  +SPP PAPR  S S      A+DPTTD
Sbjct: 477 PSTNSPPTPAPRQSSPSKSSASHASDPTTD 506

>DAB1_HUMAN (O75553) Disabled homolog 1|
          Length = 555

 Score = 31.2 bits (69), Expect = 1.4
 Identities = 16/30 (53%), Positives = 18/30 (60%), Gaps = 6/30 (20%)
 Frame = +1

Query: 43  PVNHSPPLPAPRSRSTS------AADPTTD 114
           P  +SPP PAPR  S S      A+DPTTD
Sbjct: 477 PSTNSPPTPAPRQSSPSKSSASHASDPTTD 506

>IRS1_MOUSE (P35569) Insulin receptor substrate 1 (IRS-1)|
          Length = 1233

 Score = 30.8 bits (68), Expect = 1.8
 Identities = 15/44 (34%), Positives = 22/44 (50%)
 Frame = +1

Query: 25  ASRLFAPVNHSPPLPAPRSRSTSAADPTTDTPHAVALRRGCTAD 156
           +SRL  P+NHS  +P P SR + +A        +     G T+D
Sbjct: 357 SSRLHPPLNHSRSIPMPSSRCSPSATSPVSLSSSSTSGHGSTSD 400

>ABTAP_HUMAN (Q9H501) ABT1-associated protein|
          Length = 851

 Score = 30.8 bits (68), Expect = 1.8
 Identities = 18/58 (31%), Positives = 29/58 (50%)
 Frame = -2

Query: 467 GDLADEDHLREDAASGIALVNDLEVEEQQLLDGVVLGGEDVANDGDEERRQGLAIEEE 294
           G++ D+D L ED+ S   + +D E E +    G   G +D + D +EE       E+E
Sbjct: 231 GEMCDKDALEEDSESVSEIGSDEESENEITSVGRASGDDDGSEDDEEEDEDEEEDEDE 288

>IRS1_RAT (P35570) Insulin receptor substrate 1 (IRS-1) (pp185)|
          Length = 1235

 Score = 30.8 bits (68), Expect = 1.8
 Identities = 15/44 (34%), Positives = 22/44 (50%)
 Frame = +1

Query: 25  ASRLFAPVNHSPPLPAPRSRSTSAADPTTDTPHAVALRRGCTAD 156
           +SRL  P+NHS  +P P SR + +A        +     G T+D
Sbjct: 357 SSRLHPPLNHSRSIPMPSSRCSPSATSPVSLSSSSTSGHGSTSD 400

>THIC_RHILO (Q98AZ3) Thiamine biosynthesis protein thiC|
          Length = 619

 Score = 30.0 bits (66), Expect = 3.1
 Identities = 29/87 (33%), Positives = 40/87 (45%), Gaps = 11/87 (12%)
 Frame = +3

Query: 27  ISPLRSCQPLPPS-----SG---SQISIHLRRRSNHRYPTRRRPPARVHGRSGAMDKPCT 182
           ++P  S  PLP S     SG    QI + +R  S H  PT   PP  V+  SG    P T
Sbjct: 12  LTPAVSTGPLPASRKIHKSGVLHPQIRVPMREISVH--PTAGEPPVIVYDPSGPYTDP-T 68

Query: 183 LLVHFDKGSAAMANE---IKADLEGSD 254
           +    +KG A + +E    + D+E  D
Sbjct: 69  VETSIEKGLARLRHEWITARGDVEAYD 95

>IRS1_HUMAN (P35568) Insulin receptor substrate 1 (IRS-1)|
          Length = 1242

 Score = 29.6 bits (65), Expect = 4.0
 Identities = 14/44 (31%), Positives = 22/44 (50%)
 Frame = +1

Query: 25  ASRLFAPVNHSPPLPAPRSRSTSAADPTTDTPHAVALRRGCTAD 156
           ++RL  P+NHS  +P P SR + +A        +     G T+D
Sbjct: 362 SARLHPPLNHSRSIPMPASRCSPSATSPVSLSSSSTSGHGSTSD 405

>IRS1_CERAE (Q28224) Insulin receptor substrate 1 (IRS-1)|
          Length = 1251

 Score = 29.6 bits (65), Expect = 4.0
 Identities = 14/44 (31%), Positives = 22/44 (50%)
 Frame = +1

Query: 25  ASRLFAPVNHSPPLPAPRSRSTSAADPTTDTPHAVALRRGCTAD 156
           ++RL  P+NHS  +P P SR + +A        +     G T+D
Sbjct: 362 SARLHPPLNHSRSIPMPASRCSPSATSPVSLSSSSTSGHGSTSD 405

>RSNL2_MOUSE (Q8CI96) Restin-like protein 2|
          Length = 704

 Score = 29.6 bits (65), Expect = 4.0
 Identities = 26/83 (31%), Positives = 44/83 (53%), Gaps = 5/83 (6%)
 Frame = +3

Query: 198 DKG---SAAMANEIKADLEGSDVAAKVEAMKRAVMLLLNGETLPTLFITVVRYVLPSEDH 368
           DKG   +  + + +   LE +D AA  + +K+   +LL+   LP    T  + VLP+ DH
Sbjct: 218 DKGQIPAEVVPDPVDMPLEMADAAAIAKEIKQ---MLLDAVPLPC---TSAKAVLPNSDH 271

Query: 369 TIQKLLL--LYLEIIDKRDAAGR 431
           T  + +L  L L++ D+   AG+
Sbjct: 272 TTSRAMLTSLGLKLGDRVVIAGQ 294

>IRS1B_XENLA (P84770) Insulin receptor substrate 1-B (IRS1-B) (xIRS-1-B)|
           (XIRS-L')
          Length = 1088

 Score = 29.6 bits (65), Expect = 4.0
 Identities = 14/44 (31%), Positives = 22/44 (50%)
 Frame = +1

Query: 25  ASRLFAPVNHSPPLPAPRSRSTSAADPTTDTPHAVALRRGCTAD 156
           +SRL  P+NHS  +P P +R + +A        +     G T+D
Sbjct: 358 SSRLHPPLNHSRSIPMPATRCSPSATSPVSLSSSSTSGHGSTSD 401

>DNAE2_SYMTH (Q67N73) Error-prone DNA polymerase (EC 2.7.7.7)|
          Length = 1085

 Score = 29.6 bits (65), Expect = 4.0
 Identities = 19/58 (32%), Positives = 31/58 (53%)
 Frame = -2

Query: 230  DLIRHGGGALVEVD*QRARLVHGAGSAVHPRRRATACGVSVVGSAAEVDRDLGAGRGG 57
            DL+R  GGA+     + A ++ GA   +H  RRA    V+ +  A  + ++ GAG+ G
Sbjct: 868  DLVRRTGGAVPRGPLE-ALVLAGAFDRLHSNRRAALWQVAHLLEAERIRQERGAGQAG 924

>IRS1A_XENLA (Q91615) Insulin receptor substrate 1-A (IRS1-A) (xIRS-1-A)|
           (XIRS-L)
          Length = 885

 Score = 29.6 bits (65), Expect = 4.0
 Identities = 14/44 (31%), Positives = 22/44 (50%)
 Frame = +1

Query: 25  ASRLFAPVNHSPPLPAPRSRSTSAADPTTDTPHAVALRRGCTAD 156
           +SRL  P+NHS  +P P +R + +A        +     G T+D
Sbjct: 155 SSRLHPPLNHSRSIPMPATRCSPSATSPVSLSSSSTSGHGSTSD 198

>GR43A_DROME (Q9V4K2) Putative gustatory receptor 43a|
          Length = 427

 Score = 28.9 bits (63), Expect = 6.8
 Identities = 20/63 (31%), Positives = 32/63 (50%)
 Frame = +3

Query: 270 EAMKRAVMLLLNGETLPTLFITVVRYVLPSEDHTIQKLLLLYLEIIDKRDAAGRVLPEMI 449
           E++ + V LL N   +  LFI V   +     H +     L+LE++ KRD  G +  +M+
Sbjct: 279 ESLGKCVHLLSNSFGIAVLFILVSCLL-----HLVATAYFLFLELLSKRD-NGYLWVQML 332

Query: 450 LIC 458
            IC
Sbjct: 333 WIC 335

>Y720_LEPIN (Q8F839) UPF0082 protein LA_0720|
          Length = 249

 Score = 28.9 bits (63), Expect = 6.8
 Identities = 14/35 (40%), Positives = 22/35 (62%), Gaps = 1/35 (2%)
 Frame = -2

Query: 422 GIALVNDLEVEEQQLLDGVVLGG-EDVANDGDEER 321
           G+ ++   ++ E +L+D  V GG EDV N+GD  R
Sbjct: 138 GVIVLESSQISEDELVDVAVGGGAEDVINEGDVYR 172

>Y2886_LEPIC (P62038) UPF0082 protein LIC_12886|
          Length = 249

 Score = 28.9 bits (63), Expect = 6.8
 Identities = 14/35 (40%), Positives = 22/35 (62%), Gaps = 1/35 (2%)
 Frame = -2

Query: 422 GIALVNDLEVEEQQLLDGVVLGG-EDVANDGDEER 321
           G+ ++   ++ E +L+D  V GG EDV N+GD  R
Sbjct: 138 GVIVLESSQISEDELVDVAVGGGAEDVINEGDVYR 172

>FREM2_MOUSE (Q6NVD0) FRAS1-related extracellular matrix protein 2 precursor|
           (ECM3 homolog) (NV domain-containing protein 1)
          Length = 3160

 Score = 28.9 bits (63), Expect = 6.8
 Identities = 18/54 (33%), Positives = 27/54 (50%)
 Frame = +3

Query: 294 LLLNGETLPTLFITVVRYVLPSEDHTIQKLLLLYLEIIDKRDAAGRVLPEMILI 455
           L L+  T   L +  + Y  PSED   ++L  L LEI+D   AA      M+++
Sbjct: 371 LPLSSFTQRDLRLLKIAYQPPSEDSDQERLFELELEIVDPEGAASDPFAFMVVV 424

>ISPG_AQUAE (O67496) 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (EC|
           1.17.4.3) (1-hydroxy-2-methyl-2-(E)-butenyl
           4-diphosphate synthase)
          Length = 357

 Score = 28.5 bits (62), Expect = 8.9
 Identities = 12/25 (48%), Positives = 14/25 (56%)
 Frame = -2

Query: 122 CGVSVVGSAAEVDRDLGAGRGGEWL 48
           C V+ +G A E D  L  GRG  WL
Sbjct: 300 CVVNAIGEAREADIGLACGRGFAWL 324

>ANPRC_MOUSE (P70180) Atrial natriuretic peptide clearance receptor precursor|
           (ANP-C) (ANPRC) (NPR-C) (Atrial natriuretic peptide
           C-type receptor) (EF-2)
          Length = 536

 Score = 28.5 bits (62), Expect = 8.9
 Identities = 11/44 (25%), Positives = 26/44 (59%)
 Frame = +3

Query: 237 DLEGSDVAAKVEAMKRAVMLLLNGETLPTLFITVVRYVLPSEDH 368
           DL+  D+   ++  +R V++  +G+T+  + + V R+ + S D+
Sbjct: 236 DLDLDDIVRYIQGSERVVIMCASGDTIRRIMLAVHRHGMTSGDY 279

>POTE8_HUMAN (Q6S8J7) Prostate, ovary, testis expressed protein on chromosome 8|
          Length = 498

 Score = 28.5 bits (62), Expect = 8.9
 Identities = 24/91 (26%), Positives = 42/91 (46%), Gaps = 3/91 (3%)
 Frame = +3

Query: 165 MDKPCTLLVHFDKGSAAMANEIKADLEGSDVAAKVEAMKRAVMLLLNGE--TLPTLF-IT 335
           +D+ C L V   K   A+   ++   +           + A+MLL +G    LP ++  T
Sbjct: 119 LDRQCQLHVFDSKKRTALIKAVQCQED-----------ECALMLLQHGTDPNLPDMYGNT 167

Query: 336 VVRYVLPSEDHTIQKLLLLYLEIIDKRDAAG 428
            + Y + +ED  + K LLLY   I+ ++  G
Sbjct: 168 ALHYAVYNEDKLMAKTLLLYGADIESKNKGG 198

>ANPRC_RAT (P41740) Atrial natriuretic peptide clearance receptor precursor|
           (ANP-C) (ANPRC) (NPR-C) (Atrial natriuretic peptide
           C-type receptor)
          Length = 535

 Score = 28.5 bits (62), Expect = 8.9
 Identities = 11/44 (25%), Positives = 26/44 (59%)
 Frame = +3

Query: 237 DLEGSDVAAKVEAMKRAVMLLLNGETLPTLFITVVRYVLPSEDH 368
           DL+  D+   ++  +R V++  +G+T+  + + V R+ + S D+
Sbjct: 236 DLDLDDIVRYIQGSERVVIMCASGDTIRRIMLAVHRHGMTSGDY 279


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 54,145,352
Number of Sequences: 219361
Number of extensions: 966474
Number of successful extensions: 4812
Number of sequences better than 10.0: 29
Number of HSP's better than 10.0 without gapping: 4416
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4795
length of database: 80,573,946
effective HSP length: 103
effective length of database: 57,979,763
effective search space used: 3014947676
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)