>CUL1_ARATH (Q94AH6) Cullin-1|
          Length = 738

 Score =  167 bits (424), Expect = 9e-42
 Identities = 78/93 (83%), Positives = 84/93 (90%)
 Frame = +3

Query: 186 ERKTVDLEEGWAFMQKGITKLKNILEGKPEPQFSSEDYMMLYTTIYNMCTQKPPHDYSQQ 365
           ERKT+DLE+GW +MQ GITKLK ILEG  EP F SE YMMLYTTIYNMCTQKPPHDYSQQ
Sbjct: 2   ERKTIDLEQGWDYMQTGITKLKRILEGLNEPAFDSEQYMMLYTTIYNMCTQKPPHDYSQQ 61

Query: 366 LYDKYRESFEEYISSMVLPSLREKHDEFMLREL 464
           LYDKYRE+FEEYI+S VLP+LREKHDEFMLREL
Sbjct: 62  LYDKYREAFEEYINSTVLPALREKHDEFMLREL 94

>CUL6_CAEEL (Q21346) Cullin-6|
          Length = 729

 Score = 32.3 bits (72), Expect = 0.62
 Identities = 23/82 (28%), Positives = 34/82 (41%), Gaps = 8/82 (9%)
 Frame = +3

Query: 198 VDLEEGWAFMQKGITKLKNILEGKPEPQFSSEDYMMLYTTIYNMCT--------QKPPHD 353
           + +E  W  +Q G+  L            S + YMMLY  +YN+CT           P  
Sbjct: 1   MSIEAVWGTLQDGLNLLYR------REHMSKKYYMMLYDAVYNICTTTTLANSNNNSPEF 54

Query: 354 YSQQLYDKYRESFEEYISSMVL 419
            S+ LY    +  E YI + V+
Sbjct: 55  ASEFLY----KQLENYIRTYVI 72

>CUL1_DROME (Q24311) Cullin homolog 1 (Lin-19 homolog protein)|
          Length = 774

 Score = 32.0 bits (71), Expect = 0.80
 Identities = 21/89 (23%), Positives = 42/89 (47%), Gaps = 13/89 (14%)
 Frame = +3

Query: 189 RKTVDLEEGWAFMQKGITKLKNILEGKPEPQFSSEDYMMLYTTIYNMCT--QKPPHDYS- 359
           +K V+L++ W+ + +GI ++      + E   +   YM  YT +Y+ CT     P   S 
Sbjct: 11  QKLVNLDDIWSELVEGIMQVF-----EHEKSLTRSQYMRFYTHVYDYCTSVSAAPSGRSS 65

Query: 360 ----------QQLYDKYRESFEEYISSMV 416
                     ++LYD+  +  + Y+S ++
Sbjct: 66  GKTGGAQLVGKKLYDRLEQFLKSYLSELL 94

>CDC53_YEAST (Q12018) Cell division control protein 53 (Cullin-A) (E3 ubiquitin|
           ligase complex SCF subunit CDC53)
          Length = 815

 Score = 31.2 bits (69), Expect = 1.4
 Identities = 17/53 (32%), Positives = 24/53 (45%), Gaps = 6/53 (11%)
 Frame = +3

Query: 201 DLEEGWAFMQKGITKLKNILEGKPEPQ------FSSEDYMMLYTTIYNMCTQK 341
           DLE  W F++ GI ++    + +           S   YM +YT IYN C  K
Sbjct: 10  DLEATWNFIEPGINQILGNEKNQASTSKRVYKILSPTMYMEVYTAIYNYCVNK 62

>CUL1_CAEEL (Q17389) Cullin-1 (Abnormal cell lineage protein 19)|
          Length = 780

 Score = 31.2 bits (69), Expect = 1.4
 Identities = 19/56 (33%), Positives = 26/56 (46%), Gaps = 2/56 (3%)
 Frame = +3

Query: 174 MTTHE--RKTVDLEEGWAFMQKGITKLKNILEGKPEPQFSSEDYMMLYTTIYNMCT 335
           MT  E  R T D E  W  +Q G+               + +DYM LYT++Y+ CT
Sbjct: 1   MTNSEPRRMTCDSEVVWKKLQDGLDVAYR------RENMAPKDYMTLYTSVYDYCT 50

>JEM1_YEAST (P40358) DnaJ-like chaperone JEM1 precursor (DnaJ-like protein of|
           the ER membrane 1)
          Length = 645

 Score = 30.4 bits (67), Expect = 2.3
 Identities = 16/65 (24%), Positives = 32/65 (49%), Gaps = 2/65 (3%)
 Frame = +3

Query: 210 EGWAFMQKGITKLKNILEGKPEPQFSSEDYMMLY--TTIYNMCTQKPPHDYSQQLYDKYR 383
           E W   Q   ++ K + E      ++S  ++++Y   +I N    KP   + +QLYD+  
Sbjct: 410 ETWKHYQDAKSEQKPLPETVLSDVWNSNPHLLMYMVNSILNKSRSKPHSQFKKQLYDQIN 469

Query: 384 ESFEE 398
           + F++
Sbjct: 470 KFFQD 474

>CUL1_PONPY (Q5R4G6) Cullin-1 (CUL-1)|
          Length = 776

 Score = 29.6 bits (65), Expect = 4.0
 Identities = 15/51 (29%), Positives = 24/51 (47%)
 Frame = +3

Query: 183 HERKTVDLEEGWAFMQKGITKLKNILEGKPEPQFSSEDYMMLYTTIYNMCT 335
           H  K + L++ W  ++ GI ++            +   YM LYT +YN CT
Sbjct: 10  HGLKQIGLDQIWDDLRAGIQQVYT------RQSMAKSRYMELYTHVYNYCT 54

>CUL1_MOUSE (Q9WTX6) Cullin-1 (CUL-1)|
          Length = 776

 Score = 29.6 bits (65), Expect = 4.0
 Identities = 15/51 (29%), Positives = 24/51 (47%)
 Frame = +3

Query: 183 HERKTVDLEEGWAFMQKGITKLKNILEGKPEPQFSSEDYMMLYTTIYNMCT 335
           H  K + L++ W  ++ GI ++            +   YM LYT +YN CT
Sbjct: 10  HGLKQIGLDQIWDDLRAGIQQVYT------RQSMAKSRYMELYTHVYNYCT 54

>CUL1_HUMAN (Q13616) Cullin-1 (CUL-1)|
          Length = 776

 Score = 29.6 bits (65), Expect = 4.0
 Identities = 15/51 (29%), Positives = 24/51 (47%)
 Frame = +3

Query: 183 HERKTVDLEEGWAFMQKGITKLKNILEGKPEPQFSSEDYMMLYTTIYNMCT 335
           H  K + L++ W  ++ GI ++            +   YM LYT +YN CT
Sbjct: 10  HGLKQIGLDQIWDDLRAGIQQVYT------RQSMAKSRYMELYTHVYNYCT 54

>AMA1_PLAFH (P50491) Apical membrane antigen 1 precursor (Merozoite surface|
           antigen)
          Length = 622

 Score = 28.9 bits (63), Expect = 6.8
 Identities = 18/66 (27%), Positives = 30/66 (45%), Gaps = 6/66 (9%)
 Frame = +3

Query: 279 QFSSEDYMMLYTTIYNMCTQKPPHDYSQQL--YDKYRESFEEYISSMV----LPSLREKH 440
           +FS+ D       ++ +     P  Y Q L  Y+K +E F+   +SM+    LP+   K 
Sbjct: 328 EFSANDLFECNKLVFELSASDQPKQYEQHLTDYEKIKEGFKNKNASMIKSAFLPTGAFKA 387

Query: 441 DEFMLR 458
           D +  R
Sbjct: 388 DRYKSR 393

>AMA1_PLAF8 (P50492) Apical membrane antigen 1 precursor (Merozoite surface|
           antigen)
          Length = 622

 Score = 28.9 bits (63), Expect = 6.8
 Identities = 18/66 (27%), Positives = 30/66 (45%), Gaps = 6/66 (9%)
 Frame = +3

Query: 279 QFSSEDYMMLYTTIYNMCTQKPPHDYSQQL--YDKYRESFEEYISSMV----LPSLREKH 440
           +FS+ D       ++ +     P  Y Q L  Y+K +E F+   +SM+    LP+   K 
Sbjct: 328 EFSANDLFECNKLVFELSASDQPKQYEQHLTDYEKIKEGFKNKNASMIKSAFLPTGAFKA 387

Query: 441 DEFMLR 458
           D +  R
Sbjct: 388 DRYKSR 393

>ABCA1_MOUSE (P41233) ATP-binding cassette sub-family A member 1 (ATP-binding|
            cassette transporter 1) (ATP-binding cassette 1) (ABC-1)
          Length = 2261

 Score = 28.5 bits (62), Expect = 8.9
 Identities = 13/29 (44%), Positives = 19/29 (65%)
 Frame = -1

Query: 123  SSCRVASSPLSCVGKENGRTRREGKAGRG 37
            SSCR +SS +SC+ KE+  ++    AG G
Sbjct: 1140 SSCRNSSSTVSCLKKEDSVSQSSSDAGLG 1168

>IF4G1_HUMAN (Q04637) Eukaryotic translation initiation factor 4 gamma 1|
           (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1) (p220)
          Length = 1600

 Score = 28.5 bits (62), Expect = 8.9
 Identities = 25/110 (22%), Positives = 46/110 (41%), Gaps = 1/110 (0%)
 Frame = +3

Query: 96  GATTRPDTS*GSGEPPRPDPTXXXXXMTTHERKTVDLEEGWAFMQKGITKLKNILEGKPE 275
           G+   P++  GSG PPRP+                + +E W   +  I   +NI  G+ +
Sbjct: 551 GSNPGPESE-GSGVPPRPE----------------EADETWDSKEDKIHNAENIQPGEQK 593

Query: 276 PQFSSEDYMMLYTTIYNMCTQKPPHDYSQQLYDK-YRESFEEYISSMVLP 422
            ++ S+ +             KPP+   ++ YD+ +   F+   +SM  P
Sbjct: 594 YEYKSDQW-------------KPPNLEEKKRYDREFLLGFQFIFASMQKP 630


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 46,191,063
Number of Sequences: 219361
Number of extensions: 777092
Number of successful extensions: 2770
Number of sequences better than 10.0: 13
Number of HSP's better than 10.0 without gapping: 2708
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2769
length of database: 80,573,946
effective HSP length: 103
effective length of database: 57,979,763
effective search space used: 3014947676
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)