ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | bastl29g09 |
|---|---|
| Clone Library Name | barley_pub |
>COPA_BOVIN (Q27954) Coatomer subunit alpha (Alpha-coat protein) (Alpha-COP)| (HEPCOP) (HEP-COP) [Contains: Xenin (Xenopsin-related peptide); Proxenin] Length = 1224 Score = 255 bits (651), Expect = 5e-68 Identities = 118/157 (75%), Positives = 134/157 (85%), Gaps = 3/157 (1%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPA-- 174 R+WNWQSRTCV VLTGHNHYVMCA FHP EDLVVSASLDQTVRVWDI LRKK +SP Sbjct: 118 RVWNWQSRTCVCVLTGHNHYVMCAQFHPSEDLVVSASLDQTVRVWDISGLRKKNLSPGAV 177 Query: 175 -DDIMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMN 351 D+ +T DLFG DAVVK+VLEGHDRGVNWA+FHPT+PLIVSGADDRQVK+WRMN Sbjct: 178 ESDVRGIT--GVDLFGTTDAVVKHVLEGHDRGVNWAAFHPTMPLIVSGADDRQVKIWRMN 235 Query: 352 DTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSEDKA 462 ++KAWEVDT RGH NNVSC +FH +Q++I+SNSEDK+ Sbjct: 236 ESKAWEVDTCRGHYNNVSCAVFHPRQELILSNSEDKS 272 Score = 56.6 bits (135), Expect = 3e-08 Identities = 37/153 (24%), Positives = 62/153 (40%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 ++W+++ T + H+ V FH ++ L VS D ++VW+ R Sbjct: 34 QLWDYRMCTLIDKFDEHDGPVRGIDFHKQQPLFVSGGDDYKIKVWNYKLRR--------- 84 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTK 360 + L GH + FH P I+S +DD+ +++W Sbjct: 85 ------------------CLFTLLGHLDYIRTTFFHHEYPWILSASDDQTIRVWNWQSRT 126 Query: 361 AWEVDTLRGHMNNVSCVMFHAKQDIIVSNSEDK 459 V L GH + V C FH +D++VS S D+ Sbjct: 127 C--VCVLTGHNHYVMCAQFHPSEDLVVSASLDQ 157 Score = 46.2 bits (108), Expect = 5e-05 Identities = 19/43 (44%), Positives = 30/43 (69%) Frame = +1 Query: 13 WQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI 141 W+ TC GH + V CA FHP+++L++S S D+++RVWD+ Sbjct: 240 WEVDTC----RGHYNNVSCAVFHPRQELILSNSEDKSIRVWDM 278 Score = 31.2 bits (69), Expect = 1.5 Identities = 18/63 (28%), Positives = 29/63 (46%) Frame = +1 Query: 268 VNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSN 447 V SFHP P I++ + ++LW + +D H V + FH +Q + VS Sbjct: 12 VKGLSFHPKRPWILTSLHNGVIQLW--DYRMCTLIDKFDEHDGPVRGIDFHKQQPLFVSG 69 Query: 448 SED 456 +D Sbjct: 70 GDD 72
>COPA_HUMAN (P53621) Coatomer subunit alpha (Alpha-coat protein) (Alpha-COP)| (HEPCOP) (HEP-COP) [Contains: Xenin (Xenopsin-related peptide); Proxenin] Length = 1224 Score = 254 bits (650), Expect = 6e-68 Identities = 118/157 (75%), Positives = 134/157 (85%), Gaps = 3/157 (1%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPA-- 174 R+WNWQSRTCV VLTGHNHYVMCA FHP EDLVVSASLDQTVRVWDI LRKK +SP Sbjct: 118 RVWNWQSRTCVCVLTGHNHYVMCAQFHPTEDLVVSASLDQTVRVWDISGLRKKNLSPGAV 177 Query: 175 -DDIMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMN 351 D+ +T DLFG DAVVK+VLEGHDRGVNWA+FHPT+PLIVSGADDRQVK+WRMN Sbjct: 178 ESDVRGIT--GVDLFGTTDAVVKHVLEGHDRGVNWAAFHPTMPLIVSGADDRQVKIWRMN 235 Query: 352 DTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSEDKA 462 ++KAWEVDT RGH NNVSC +FH +Q++I+SNSEDK+ Sbjct: 236 ESKAWEVDTCRGHYNNVSCAVFHPRQELILSNSEDKS 272 Score = 56.2 bits (134), Expect = 4e-08 Identities = 37/153 (24%), Positives = 62/153 (40%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 ++W+++ T + H+ V FH ++ L VS D ++VW+ R Sbjct: 34 QLWDYRMCTLIDKFDEHDGPVRGIDFHKQQPLFVSGGDDYKIKVWNYKLRR--------- 84 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTK 360 + L GH + FH P I+S +DD+ +++W Sbjct: 85 ------------------CLFTLLGHLDYIRTTFFHHEYPWILSASDDQTIRVWNWQSRT 126 Query: 361 AWEVDTLRGHMNNVSCVMFHAKQDIIVSNSEDK 459 V L GH + V C FH +D++VS S D+ Sbjct: 127 C--VCVLTGHNHYVMCAQFHPTEDLVVSASLDQ 157 Score = 46.2 bits (108), Expect = 5e-05 Identities = 19/43 (44%), Positives = 30/43 (69%) Frame = +1 Query: 13 WQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI 141 W+ TC GH + V CA FHP+++L++S S D+++RVWD+ Sbjct: 240 WEVDTC----RGHYNNVSCAVFHPRQELILSNSEDKSIRVWDM 278 Score = 31.2 bits (69), Expect = 1.5 Identities = 18/63 (28%), Positives = 29/63 (46%) Frame = +1 Query: 268 VNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSN 447 V SFHP P I++ + ++LW + +D H V + FH +Q + VS Sbjct: 12 VKGLSFHPKRPWILTSLHNGVIQLW--DYRMCTLIDKFDEHDGPVRGIDFHKQQPLFVSG 69 Query: 448 SED 456 +D Sbjct: 70 GDD 72
>COPA_YEAST (P53622) Coatomer subunit alpha (Alpha-coat protein) (Alpha-COP)| Length = 1201 Score = 211 bits (538), Expect = 6e-55 Identities = 99/156 (63%), Positives = 121/156 (77%), Gaps = 3/156 (1%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 RIWNWQ+R +A LTGHNH+VMCA FHP +DL+VSASLD+T+R+WDI LRK+ +P Sbjct: 120 RIWNWQNRKEIACLTGHNHFVMCAQFHPTDDLIVSASLDETIRIWDISGLRKRHSAPGTS 179 Query: 181 IM--RLTQMNTDLFGGV-DAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMN 351 +++ L G + D VVK++LEGH RGVNWASFHPTLPLIVSG+DDRQVKLWRM+ Sbjct: 180 SFEEQMSAQQNLLDGSLGDCVVKFILEGHTRGVNWASFHPTLPLIVSGSDDRQVKLWRMS 239 Query: 352 DTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSEDK 459 TKAWEVDT RGH NNV V+FH Q++I+S EDK Sbjct: 240 ATKAWEVDTCRGHTNNVDSVIFHPHQNLIISVGEDK 275 Score = 70.1 bits (170), Expect = 3e-12 Identities = 43/153 (28%), Positives = 66/153 (43%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 ++W+++ T + H V FHP + + VSA D T++VW + + Sbjct: 36 QLWDYRMGTLLHRFEDHEGPVRGLDFHPTQPIFVSAGDDYTIKVWSLDTNK--------- 86 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTK 360 Y L GH V FH LP I+S +DD+ +++W + K Sbjct: 87 ------------------CLYTLTGHLDYVRTVFFHRELPWIISASDDQTIRIWNWQNRK 128 Query: 361 AWEVDTLRGHMNNVSCVMFHAKQDIIVSNSEDK 459 E+ L GH + V C FH D+IVS S D+ Sbjct: 129 --EIACLTGHNHFVMCAQFHPTDDLIVSASLDE 159 Score = 40.4 bits (93), Expect = 0.002 Identities = 17/43 (39%), Positives = 26/43 (60%) Frame = +1 Query: 13 WQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI 141 W+ TC GH + V FHP ++L++S D+T+RVWD+ Sbjct: 244 WEVDTC----RGHTNNVDSVIFHPHQNLIISVGEDKTLRVWDL 282
>COPB2_MOUSE (O55029) Coatomer subunit beta' (Beta'-coat protein) (Beta'-COP)| (p102) Length = 905 Score = 96.7 bits (239), Expect = 3e-20 Identities = 56/156 (35%), Positives = 81/156 (51%), Gaps = 4/156 (2%) Frame = +1 Query: 1 RIWNWQSR-TCVAVLTGHNHYVMCASFHPKED-LVVSASLDQTVRVWDIGALRKKTVSPA 174 ++W+W + +C V GH HYVM +PK++ SASLD+T++VW +G+ SP Sbjct: 124 KLWDWDKKWSCSQVFEGHTHYVMQIVINPKDNNQFASASLDRTIKVWQLGSS-----SP- 177 Query: 175 DDIMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHP--TLPLIVSGADDRQVKLWRM 348 + LEGH++GVN ++ P ++SGADDR VK+W Sbjct: 178 ---------------------NFTLEGHEKGVNCIDYYSGGDKPYLISGADDRLVKIWDY 216 Query: 349 NDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 + V TL GH NVSC FH + II++ SED Sbjct: 217 QNKTC--VQTLEGHAQNVSCASFHPELPIIITGSED 250 Score = 58.2 bits (139), Expect = 1e-08 Identities = 23/51 (45%), Positives = 34/51 (66%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALR 153 +IW++Q++TCV L GH V CASFHP+ ++++ S D TVR+W R Sbjct: 212 KIWDYQNKTCVQTLEGHAQNVSCASFHPELPIIITGSEDGTVRIWHSSTYR 262 Score = 40.8 bits (94), Expect = 0.002 Identities = 37/165 (22%), Positives = 62/165 (37%), Gaps = 21/165 (12%) Frame = +1 Query: 40 LTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIG--------------------ALRKK 159 LT + V HP E ++++ + +V VW+ RK Sbjct: 11 LTARSDRVKSVDLHPTEPWMLASLYNGSVCVWNHETQTLVKTFEVCDLPVRAAKFVARKN 70 Query: 160 TVSPADDIMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKL 339 V D M++ N + V ++ E H + + HPT P I++ +DD +KL Sbjct: 71 WVVTGADDMQIRVFNYNTLERV-----HMFEAHSDYIRCIAVHPTQPFILTSSDDMLIKL 125 Query: 340 WRMNDTKAWEV-DTLRGHMNNVSCVMFHAKQDIIVSNSEDKAFAS 471 W + K W GH H I+++ ++ FAS Sbjct: 126 WDWD--KKWSCSQVFEGHT--------HYVMQIVINPKDNNQFAS 160
>COPB2_HUMAN (P35606) Coatomer subunit beta' (Beta'-coat protein) (Beta'-COP)| (p102) Length = 905 Score = 96.7 bits (239), Expect = 3e-20 Identities = 56/156 (35%), Positives = 81/156 (51%), Gaps = 4/156 (2%) Frame = +1 Query: 1 RIWNWQSR-TCVAVLTGHNHYVMCASFHPKED-LVVSASLDQTVRVWDIGALRKKTVSPA 174 ++W+W + +C V GH HYVM +PK++ SASLD+T++VW +G+ SP Sbjct: 123 KLWDWDKKWSCSQVFEGHTHYVMQIVINPKDNNQFASASLDRTIKVWQLGSS-----SP- 176 Query: 175 DDIMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHP--TLPLIVSGADDRQVKLWRM 348 + LEGH++GVN ++ P ++SGADDR VK+W Sbjct: 177 ---------------------NFTLEGHEKGVNCIDYYSGGDKPYLISGADDRLVKIWDY 215 Query: 349 NDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 + V TL GH NVSC FH + II++ SED Sbjct: 216 QNKTC--VQTLEGHAQNVSCASFHPELPIIITGSED 249 Score = 58.2 bits (139), Expect = 1e-08 Identities = 23/51 (45%), Positives = 34/51 (66%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALR 153 +IW++Q++TCV L GH V CASFHP+ ++++ S D TVR+W R Sbjct: 211 KIWDYQNKTCVQTLEGHAQNVSCASFHPELPIIITGSEDGTVRIWHSSTYR 261 Score = 40.8 bits (94), Expect = 0.002 Identities = 37/165 (22%), Positives = 62/165 (37%), Gaps = 21/165 (12%) Frame = +1 Query: 40 LTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIG--------------------ALRKK 159 LT + V HP E ++++ + +V VW+ RK Sbjct: 10 LTARSDRVKSVDLHPTEPWMLASLYNGSVCVWNHETQTLVKTFEVCDLPVRAAKFVARKN 69 Query: 160 TVSPADDIMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKL 339 V D M++ N + V ++ E H + + HPT P I++ +DD +KL Sbjct: 70 WVVTGADDMQIRVFNYNTLERV-----HMFEAHSDYIRCIAVHPTQPFILTSSDDMLIKL 124 Query: 340 WRMNDTKAWEV-DTLRGHMNNVSCVMFHAKQDIIVSNSEDKAFAS 471 W + K W GH H I+++ ++ FAS Sbjct: 125 WDWD--KKWSCSQVFEGHT--------HYVMQIVINPKDNNQFAS 159
>COPB2_BOVIN (P35605) Coatomer subunit beta' (Beta'-coat protein) (Beta'-COP)| (p102) Length = 905 Score = 96.7 bits (239), Expect = 3e-20 Identities = 56/156 (35%), Positives = 81/156 (51%), Gaps = 4/156 (2%) Frame = +1 Query: 1 RIWNWQSR-TCVAVLTGHNHYVMCASFHPKED-LVVSASLDQTVRVWDIGALRKKTVSPA 174 ++W+W + +C V GH HYVM +PK++ SASLD+T++VW +G+ SP Sbjct: 123 KLWDWDKKWSCSQVFEGHTHYVMQIVINPKDNNQFASASLDRTIKVWQLGSS-----SP- 176 Query: 175 DDIMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHP--TLPLIVSGADDRQVKLWRM 348 + LEGH++GVN ++ P ++SGADDR VK+W Sbjct: 177 ---------------------NFTLEGHEKGVNCIDYYSGGDKPYLISGADDRLVKIWDY 215 Query: 349 NDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 + V TL GH NVSC FH + II++ SED Sbjct: 216 QNKTC--VQTLEGHAQNVSCASFHPELPIIITGSED 249 Score = 58.2 bits (139), Expect = 1e-08 Identities = 23/51 (45%), Positives = 34/51 (66%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALR 153 +IW++Q++TCV L GH V CASFHP+ ++++ S D TVR+W R Sbjct: 211 KIWDYQNKTCVQTLEGHAQNVSCASFHPELPIIITGSEDGTVRIWHSSTYR 261 Score = 40.8 bits (94), Expect = 0.002 Identities = 37/165 (22%), Positives = 62/165 (37%), Gaps = 21/165 (12%) Frame = +1 Query: 40 LTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIG--------------------ALRKK 159 LT + V HP E ++++ + +V VW+ RK Sbjct: 10 LTARSDRVKSVDLHPTEPWMLASLYNGSVCVWNHETQTLVKTFEVCDLPVRAAKFVARKN 69 Query: 160 TVSPADDIMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKL 339 V D M++ N + V ++ E H + + HPT P I++ +DD +KL Sbjct: 70 WVVTGADDMQIRVFNYNTLERV-----HMFEAHSDYIRCIAVHPTQPFILTSSDDMLIKL 124 Query: 340 WRMNDTKAWEV-DTLRGHMNNVSCVMFHAKQDIIVSNSEDKAFAS 471 W + K W GH H I+++ ++ FAS Sbjct: 125 WDWD--KKWSCSQVFEGHT--------HYVMQIVINPKDNNQFAS 159
>COPB2_RAT (O35142) Coatomer subunit beta' (Beta'-coat protein) (Beta'-COP)| (p102) Length = 904 Score = 94.0 bits (232), Expect = 2e-19 Identities = 55/156 (35%), Positives = 80/156 (51%), Gaps = 4/156 (2%) Frame = +1 Query: 1 RIWNWQSR-TCVAVLTGHNHYVMCASFHPKED-LVVSASLDQTVRVWDIGALRKKTVSPA 174 ++W+W + +C V GH HYVM +PK++ SASLD+T++VW +G+ SP Sbjct: 123 KLWDWDKKWSCSQVFEGHTHYVMQIVINPKDNNQFASASLDRTIKVWQLGSS-----SP- 176 Query: 175 DDIMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHP--TLPLIVSGADDRQVKLWRM 348 + LEGH++GVN ++ P ++SGADDR VK+W Sbjct: 177 ---------------------NFTLEGHEKGVNCIDYYSGGDKPYLISGADDRLVKIWDY 215 Query: 349 NDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 + V T GH NVSC FH + II++ SED Sbjct: 216 QNKTC--VQTPEGHAQNVSCATFHPELPIIITGSED 249 Score = 54.3 bits (129), Expect = 2e-07 Identities = 21/51 (41%), Positives = 33/51 (64%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALR 153 +IW++Q++TCV GH V CA+FHP+ ++++ S D TVR+W R Sbjct: 211 KIWDYQNKTCVQTPEGHAQNVSCATFHPELPIIITGSEDGTVRIWHSSTYR 261 Score = 40.0 bits (92), Expect = 0.003 Identities = 37/165 (22%), Positives = 62/165 (37%), Gaps = 21/165 (12%) Frame = +1 Query: 40 LTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIG--------------------ALRKK 159 LT + V HP E ++++ + +V VW+ RK Sbjct: 10 LTAMSDRVKSVDLHPTEPWMLASLYNGSVCVWNHETQTLVKTFEVCDLPVRAAKFVARKN 69 Query: 160 TVSPADDIMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKL 339 V D M++ N + V ++ E H + + HPT P I++ +DD +KL Sbjct: 70 WVVTGADDMQIRVFNYNTLERV-----HMFEAHSDYIRCIAVHPTQPFILTSSDDMLIKL 124 Query: 340 WRMNDTKAWEV-DTLRGHMNNVSCVMFHAKQDIIVSNSEDKAFAS 471 W + K W GH H I+++ ++ FAS Sbjct: 125 WDWD--KKWSCSQVFEGHT--------HYVMQIVINPKDNNQFAS 159
>COPB2_SCHPO (O42937) Probable coatomer subunit beta' (Beta'-coat protein)| (Beta'-COP) Length = 796 Score = 87.4 bits (215), Expect = 2e-17 Identities = 54/156 (34%), Positives = 78/156 (50%), Gaps = 4/156 (2%) Frame = +1 Query: 1 RIWNWQ-SRTCVAVLTGHNHYVMCASFHPKE-DLVVSASLDQTVRVWDIGALRKKTVSPA 174 + +NW S CV GH+ YVM + +PK+ + S+ LD TV+VW G+ Sbjct: 123 KCFNWDMSWKCVQTFEGHSRYVMSLAINPKDTNTFASSCLDGTVKVWSFGS--------- 173 Query: 175 DDIMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPT--LPLIVSGADDRQVKLWRM 348 +V + L+ HDRGVN+ +++P P +++ DD +K+W Sbjct: 174 ------------------SVANFTLQAHDRGVNYVNYYPAGDKPYLITAGDDNLIKVWDY 215 Query: 349 NDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 TKA V L GH NNVS FH+K II+S SED Sbjct: 216 Q-TKAC-VRILEGHTNNVSFAFFHSKFPIIISGSED 249 Score = 49.7 bits (117), Expect = 4e-06 Identities = 18/45 (40%), Positives = 31/45 (68%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVW 135 ++W++Q++ CV +L GH + V A FH K +++S S D TV++W Sbjct: 211 KVWDYQTKACVRILEGHTNNVSFAFFHSKFPIIISGSEDGTVKIW 255 Score = 38.1 bits (87), Expect = 0.012 Identities = 33/145 (22%), Positives = 57/145 (39%), Gaps = 16/145 (11%) Frame = +1 Query: 40 LTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGA---LRKKTVS--PADDIMRLTQMN 204 L H V FHP E V+++ + V +W+ +R ++ P + + N Sbjct: 10 LLSHTERVKAVDFHPTEPWVIASHYNGQVGIWNYNTQTLVRSFDINDVPIRACAFIARKN 69 Query: 205 TDLFGGVDAVVKYV----------LEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMND 354 + G D V+ E H + HPT P +++ +DD +K + N Sbjct: 70 WFVCGSDDFQVRVYNYNTGEKVTQFEAHPDYIRALVVHPTQPFLLTSSDDMTIKCF--NW 127 Query: 355 TKAWE-VDTLRGHMNNVSCVMFHAK 426 +W+ V T GH V + + K Sbjct: 128 DMSWKCVQTFEGHSRYVMSLAINPK 152
>PKWA_THECU (P49695) Probable serine/threonine-protein kinase pkwA (EC 2.7.11.1)| Length = 742 Score = 87.0 bits (214), Expect = 2e-17 Identities = 56/166 (33%), Positives = 84/166 (50%), Gaps = 14/166 (8%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTV--SPA 174 R+WN + T AVL GH YV +F P +V S S D T+R+WD+ +++ V +PA Sbjct: 568 RLWNVATGTEHAVLKGHTDYVYAVAFSPDGSMVASGSRDGTIRLWDVATGKERDVLQAPA 627 Query: 175 DDIMRL--TQMNTDLFGGVDAVVK----------YVLEGHDRGVNWASFHPTLPLIVSGA 318 ++++ L + + L G D+ V + EGH V +F P L+ SG+ Sbjct: 628 ENVVSLAFSPDGSMLVHGSDSTVHLWDVASGEALHTFEGHTDWVRAVAFSPDGALLASGS 687 Query: 319 DDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 DDR ++LW + + E TL GH V V FH + + S SED Sbjct: 688 DDRTIRLWDVAAQE--EHTTLEGHTEPVHSVAFHPEGTTLASASED 731 Score = 57.8 bits (138), Expect = 1e-08 Identities = 41/151 (27%), Positives = 60/151 (39%) Frame = +1 Query: 4 IWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDI 183 +W+ S + L GH +V +F P L+ S S D TVR+WD+ A ++ Sbjct: 485 VWDVASGDELHTLEGHTDWVRAVAFSPDGALLASGSDDATVRLWDVAAAEERA------- 537 Query: 184 MRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKA 363 V EGH V +F P ++ SG+ D +LW N Sbjct: 538 --------------------VFEGHTHYVLDIAFSPDGSMVASGSRDGTARLW--NVATG 575 Query: 364 WEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 E L+GH + V V F ++ S S D Sbjct: 576 TEHAVLKGHTDYVYAVAFSPDGSMVASGSRD 606 Score = 51.2 bits (121), Expect = 1e-06 Identities = 28/113 (24%), Positives = 47/113 (41%) Frame = +1 Query: 4 IWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDI 183 +W+ S + GH +V +F P L+ S S D+T+R+WD+ A + T Sbjct: 652 LWDVASGEALHTFEGHTDWVRAVAFSPDGALLASGSDDRTIRLWDVAAQEEHTT------ 705 Query: 184 MRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLW 342 LEGH V+ +FHP + S ++D +++W Sbjct: 706 ---------------------LEGHTEPVHSVAFHPEGTTLASASEDGTIRIW 737 Score = 38.1 bits (87), Expect = 0.012 Identities = 17/47 (36%), Positives = 26/47 (55%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI 141 R+W+ ++ L GH V +FHP+ + SAS D T+R+W I Sbjct: 693 RLWDVAAQEEHTTLEGHTEPVHSVAFHPEGTTLASASEDGTIRIWPI 739
>COPB2_CAEEL (Q20168) Probable coatomer subunit beta' (Beta'-coat protein)| (Beta'-COP) Length = 1000 Score = 86.7 bits (213), Expect = 3e-17 Identities = 52/156 (33%), Positives = 78/156 (50%), Gaps = 4/156 (2%) Frame = +1 Query: 1 RIWNWQSRTCVAV-LTGHNHYVMCASFHPKED-LVVSASLDQTVRVWDIGALRKKTVSPA 174 ++W+W ++ + GH HYVM + +PK++ +ASLD+TV+VW G+ Sbjct: 124 KMWDWDNKWAMKQSFEGHTHYVMQIAINPKDNNTFATASLDKTVKVWQFGS--------- 174 Query: 175 DDIMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHP--TLPLIVSGADDRQVKLWRM 348 V + LEGH++GVN ++ P I+SGADD VK+W Sbjct: 175 ------------------NVPNFTLEGHEKGVNCVDYYHGGEKPYIISGADDHLVKIWDY 216 Query: 349 NDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 + V TL GH NVS V FH + +I++ SED Sbjct: 217 QNKTC--VQTLDGHAQNVSSVCFHPELPLIITGSED 250 Score = 52.8 bits (125), Expect = 5e-07 Identities = 21/53 (39%), Positives = 33/53 (62%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKK 159 +IW++Q++TCV L GH V FHP+ L+++ S D TVR+W R++ Sbjct: 212 KIWDYQNKTCVQTLDGHAQNVSSVCFHPELPLIITGSEDSTVRLWHANTYRQE 264 Score = 43.1 bits (100), Expect = 4e-04 Identities = 34/151 (22%), Positives = 57/151 (37%), Gaps = 20/151 (13%) Frame = +1 Query: 40 LTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGAL--------------------RKK 159 L + V C HP E +++A + V +W+ RK Sbjct: 11 LLARSDRVKCVDLHPVETWLLAALYNGNVHIWNYETQTLVKSFEVCDVPVRAAKFVPRKS 70 Query: 160 TVSPADDIMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKL 339 V D M + N + V + E H + HPTLP ++S +DD VK+ Sbjct: 71 WVVTGSDDMHIRVFNYNTLERV-----HQFEAHSDYLRSLVVHPTLPYVISSSDDMLVKM 125 Query: 340 WRMNDTKAWEVDTLRGHMNNVSCVMFHAKQD 432 W ++ A + + GH + V + + K + Sbjct: 126 WDWDNKWAMK-QSFEGHTHYVMQIAINPKDN 155
>COPB2_YEAST (P41811) Coatomer subunit beta' (Beta'-coat protein) (Beta'-COP)| Length = 889 Score = 85.5 bits (210), Expect = 7e-17 Identities = 50/156 (32%), Positives = 77/156 (49%), Gaps = 4/156 (2%) Frame = +1 Query: 1 RIWNWQSRTCVA-VLTGHNHYVMCASFHPKE-DLVVSASLDQTVRVWDIGALRKKTVSPA 174 ++WNW++ + GH H+VMC +F+PK+ S LD+TV+VW +G Sbjct: 122 KLWNWENNWALEQTFEGHEHFVMCVAFNPKDPSTFASGCLDRTVKVWSLG---------- 171 Query: 175 DDIMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPT--LPLIVSGADDRQVKLWRM 348 +T F + G +RGVN+ ++P P +++ +DD +K+W Sbjct: 172 --------QSTPNFT--------LTTGQERGVNYVDYYPLPDKPYMITASDDLTIKIWDY 215 Query: 349 NDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 V TL GHM+NVS +FH II+S SED Sbjct: 216 QTKSC--VATLEGHMSNVSFAVFHPTLPIIISGSED 249 Score = 49.7 bits (117), Expect = 4e-06 Identities = 19/46 (41%), Positives = 32/46 (69%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWD 138 +IW++Q+++CVA L GH V A FHP +++S S D T+++W+ Sbjct: 211 KIWDYQTKSCVATLEGHMSNVSFAVFHPTLPIIISGSEDGTLKIWN 256
>COPB2_DROME (O62621) Coatomer subunit beta' (Beta'-coat protein) (Beta'-COP)| Length = 914 Score = 84.7 bits (208), Expect = 1e-16 Identities = 51/171 (29%), Positives = 87/171 (50%), Gaps = 19/171 (11%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWD---IGALRKKTVSP 171 R++N+ + V H+ Y+ C + HP + LV+++S D +++W+ + A ++ Sbjct: 82 RVFNYNTLEKVHSFEAHSDYLRCIAVHPTQPLVLTSSDDMLIKLWNWEKMWACQRVFEGH 141 Query: 172 ADDIMRLT----QMNTDLFGGVDAVVK----------YVLEGHDRGVNWASFH--PTLPL 303 +M++ NT +D VK + LEGH++GVN ++ P Sbjct: 142 THYVMQIVFNPKDNNTFASASLDRTVKVWQLGSNFANFTLEGHEKGVNCVDYYHGGDKPY 201 Query: 304 IVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 ++SGADDR VK+W + V TL GH N+S V FH + I+++ SED Sbjct: 202 LISGADDRLVKIWDYQNKTC--VQTLEGHAQNISAVCFHPELPIVLTGSED 250 Score = 75.5 bits (184), Expect = 7e-14 Identities = 49/171 (28%), Positives = 81/171 (47%), Gaps = 36/171 (21%) Frame = +1 Query: 1 RIWNWQSR-TCVAVLTGHNHYVMCASFHPKED-LVVSASLDQTVRVWDIGAL-------- 150 ++WNW+ C V GH HYVM F+PK++ SASLD+TV+VW +G+ Sbjct: 124 KLWNWEKMWACQRVFEGHTHYVMQIVFNPKDNNTFASASLDRTVKVWQLGSNFANFTLEG 183 Query: 151 ---------------RKKTVSPADDIMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASF 285 + +S ADD RL + ++ + LEGH + ++ F Sbjct: 184 HEKGVNCVDYYHGGDKPYLISGADD--RLVK----IWDYQNKTCVQTLEGHAQNISAVCF 237 Query: 286 HPTLPLIVSGADDRQVKLWRMND-----------TKAWEVDTLRGHMNNVS 405 HP LP++++G++D V++W + W + ++RG NNV+ Sbjct: 238 HPELPIVLTGSEDGTVRIWHSGTYRLETCLNYGFERVWTISSMRG-TNNVA 287 Score = 43.1 bits (100), Expect = 4e-04 Identities = 35/152 (23%), Positives = 58/152 (38%), Gaps = 21/152 (13%) Frame = +1 Query: 40 LTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIG--------------------ALRKK 159 LT + V C HP E ++ A + V + + RK Sbjct: 11 LTSRSDRVKCVDLHPAEPWMLCALYNGHVHIMNYENQQMVKDFEVCDVPVRSARFVARKN 70 Query: 160 TVSPADDIMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKL 339 + D M++ N + V + E H + + HPT PL+++ +DD +KL Sbjct: 71 WILTGSDDMQIRVFNYNTLEKV-----HSFEAHSDYLRCIAVHPTQPLVLTSSDDMLIKL 125 Query: 340 WRMNDTKAWEVD-TLRGHMNNVSCVMFHAKQD 432 W N K W GH + V ++F+ K + Sbjct: 126 W--NWEKMWACQRVFEGHTHYVMQIVFNPKDN 155
>YY46_ANASP (Q8YRI1) Hypothetical WD-repeat protein alr3466| Length = 1526 Score = 80.1 bits (196), Expect = 3e-15 Identities = 46/153 (30%), Positives = 74/153 (48%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 R+W+ S+ C+ L GH ++V +F P + S S DQTVR+WDI + + Sbjct: 1141 RLWDISSKKCLYTLQGHTNWVNAVAFSPDGATLASGSGDQTVRLWDISSSK--------- 1191 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTK 360 Y+L+GH VN F+P + SG+ D+ V+LW +N +K Sbjct: 1192 ------------------CLYILQGHTSWVNSVVFNPDGSTLASGSSDQTVRLWEINSSK 1233 Query: 361 AWEVDTLRGHMNNVSCVMFHAKQDIIVSNSEDK 459 + T +GH + V+ V+F+ ++ S S DK Sbjct: 1234 C--LCTFQGHTSWVNSVVFNPDGSMLASGSSDK 1264 Score = 73.9 bits (180), Expect = 2e-13 Identities = 49/168 (29%), Positives = 76/168 (45%), Gaps = 15/168 (8%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGA----------- 147 R+W S C+ GH +V +F P ++ S S DQTVR+W I + Sbjct: 1309 RLWEISSSKCLHTFQGHTSWVSSVTFSPDGTMLASGSDDQTVRLWSISSGECLYTFLGHT 1368 Query: 148 --LRKKTVSPADDIMRLTQ--MNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSG 315 + SP I+ L+ Y L+GH+ V F P L+ SG Sbjct: 1369 NWVGSVIFSPDGAILASGSGDQTVRLWSISSGKCLYTLQGHNNWVGSIVFSPDGTLLASG 1428 Query: 316 ADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSEDK 459 +DD+ V+LW ++ + + TL GH+N+V V F + I+ S S+D+ Sbjct: 1429 SDDQTVRLWNISSGEC--LYTLHGHINSVRSVAFSSDGLILASGSDDE 1474 Score = 70.9 bits (172), Expect = 2e-12 Identities = 46/168 (27%), Positives = 79/168 (47%), Gaps = 15/168 (8%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALR--------- 153 R+W+ S C+ GH ++V +F+P ++ S S DQTVR+W+I + + Sbjct: 1267 RLWDISSSKCLHTFQGHTNWVNSVAFNPDGSMLASGSGDQTVRLWEISSSKCLHTFQGHT 1326 Query: 154 --KKTVSPADDIMRLTQMNTD----LFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSG 315 +V+ + D L + D L+ Y GH V F P ++ SG Sbjct: 1327 SWVSSVTFSPDGTMLASGSDDQTVRLWSISSGECLYTFLGHTNWVGSVIFSPDGAILASG 1386 Query: 316 ADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSEDK 459 + D+ V+LW ++ K + TL+GH N V ++F ++ S S+D+ Sbjct: 1387 SGDQTVRLWSISSGKC--LYTLQGHNNWVGSIVFSPDGTLLASGSDDQ 1432 Score = 61.2 bits (147), Expect = 1e-09 Identities = 45/168 (26%), Positives = 72/168 (42%), Gaps = 15/168 (8%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPA-D 177 R+W+ S C+ GH V F P ++ S S DQTVR+WDI + + Sbjct: 931 RLWDISSGQCLKTFKGHTSRVRSVVFSPNSLMLASGSSDQTVRLWDISSGECLYIFQGHT 990 Query: 178 DIMRLTQMNTD----LFGGVDAVVK----------YVLEGHDRGVNWASFHPTLPLIVSG 315 + N D G D V+ Y+ +GH V F ++ SG Sbjct: 991 GWVYSVAFNLDGSMLATGSGDQTVRLWDISSSQCFYIFQGHTSCVRSVVFSSDGAMLASG 1050 Query: 316 ADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSEDK 459 +DD+ V+LW ++ + TL+GH + V V+F ++ S +D+ Sbjct: 1051 SDDQTVRLWDISSGNC--LYTLQGHTSCVRSVVFSPDGAMLASGGDDQ 1096 Score = 58.9 bits (141), Expect = 7e-09 Identities = 42/166 (25%), Positives = 82/166 (49%), Gaps = 17/166 (10%) Frame = +1 Query: 13 WQSRTCVAVLT--GHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGA-----------LR 153 W++ T +LT GHN +V F ++ S S DQTVR+WDI + R Sbjct: 891 WEAATGKELLTCKGHNSWVNSVGFSQDGKMLASGSDDQTVRLWDISSGQCLKTFKGHTSR 950 Query: 154 KKTVSPADDIMRLTQMNTD----LFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGAD 321 ++V + + + L ++D L+ Y+ +GH V +F+ ++ +G+ Sbjct: 951 VRSVVFSPNSLMLASGSSDQTVRLWDISSGECLYIFQGHTGWVYSVAFNLDGSMLATGSG 1010 Query: 322 DRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSEDK 459 D+ V+LW ++ ++ + + +GH + V V+F + ++ S S+D+ Sbjct: 1011 DQTVRLWDISSSQCFYI--FQGHTSCVRSVVFSSDGAMLASGSDDQ 1054 Score = 56.6 bits (135), Expect = 3e-08 Identities = 39/129 (30%), Positives = 55/129 (42%), Gaps = 1/129 (0%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 R+W+ S C+ L GHN++V F P L+ S S DQTVR+W+I + Sbjct: 1393 RLWSISSGKCLYTLQGHNNWVGSIVFSPDGTLLASGSDDQTVRLWNISS----------- 1441 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTK 360 Y L GH V +F ++ SG+DD +KLW D K Sbjct: 1442 ----------------GECLYTLHGHINSVRSVAFSSDGLILASGSDDETIKLW---DVK 1482 Query: 361 AWE-VDTLR 384 E + TL+ Sbjct: 1483 TGECIKTLK 1491 Score = 38.5 bits (88), Expect = 0.009 Identities = 16/47 (34%), Positives = 27/47 (57%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI 141 R+WN S C+ L GH + V +F ++ S S D+T+++WD+ Sbjct: 1435 RLWNISSGECLYTLHGHINSVRSVAFSSDGLILASGSDDETIKLWDV 1481
>FBW1B_HUMAN (Q9UKB1) F-box/WD-repeat protein 11 (F-box/WD-repeat protein 1B)| (F-box and WD-repeats protein beta-TrCP2) Length = 542 Score = 73.6 bits (179), Expect = 3e-13 Identities = 50/168 (29%), Positives = 79/168 (47%), Gaps = 16/168 (9%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI--GALRKKTVSPA 174 +IW+ S C+ VLTGH V+C + E ++V+ S D TVRVWD+ G + + Sbjct: 263 KIWDKTSLECLKVLTGHTGSVLCLQY--DERVIVTGSSDSTVRVWDVNTGEVLNTLIHHN 320 Query: 175 DDIMRLTQMN--------------TDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVS 312 + ++ L N D+ D ++ VL GH VN F IVS Sbjct: 321 EAVLHLRFSNGLMVTCSKDRSIAVWDMASATDITLRRVLVGHRAAVNVVDFDD--KYIVS 378 Query: 313 GADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 + DR +K+W + + V TL GH ++C+ + + ++VS S D Sbjct: 379 ASGDRTIKVWSTSTCEF--VRTLNGHKRGIACLQY--RDRLVVSGSSD 422 Score = 45.1 bits (105), Expect = 1e-04 Identities = 48/159 (30%), Positives = 66/159 (41%), Gaps = 11/159 (6%) Frame = +1 Query: 13 WQSRTC--VAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI--GALRKKTVSPADD 180 W + TC V L GH + C + ++ LVVS S D T+R+WDI GA + Sbjct: 388 WSTSTCEFVRTLNGHKRGIACLQY--RDRLVVSGSSDNTIRLWDIECGACLR-------- 437 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMN--- 351 VLEGH+ V F IVSGA D ++K+W + Sbjct: 438 ---------------------VLEGHEELVRCIRFDNKR--IVSGAYDGKIKVWDLQAAL 474 Query: 352 DTKAWE----VDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 D +A + TL H V + F Q I+S+S D Sbjct: 475 DPRAPASTLCLRTLVEHSGRVFRLQFDEFQ--IISSSHD 511 Score = 40.4 bits (93), Expect = 0.002 Identities = 18/49 (36%), Positives = 27/49 (55%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGA 147 R+W+ + C+ VL GH V C F K +VS + D ++VWD+ A Sbjct: 426 RLWDIECGACLRVLEGHEELVRCIRFDNKR--IVSGAYDGKIKVWDLQA 472 Score = 31.2 bits (69), Expect = 1.5 Identities = 16/51 (31%), Positives = 27/51 (52%) Frame = +1 Query: 304 IVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 I+SG D +K+W + +V L GH +V C+ + + +IV+ S D Sbjct: 253 IISGLRDNSIKIWDKTSLECLKV--LTGHTGSVLCLQYDER--VIVTGSSD 299
>LIN23_CAEEL (Q09990) F-box/WD-repeat protein lin-23 (Abnormal cell lineage| protein 23) Length = 665 Score = 73.2 bits (178), Expect = 3e-13 Identities = 48/168 (28%), Positives = 80/168 (47%), Gaps = 16/168 (9%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI--GALRKKTVSPA 174 +IW+ + +C +L+GH V+C + + +++S S D TVRVWD+ G K + Sbjct: 245 KIWDRKDYSCSRILSGHTGSVLCLQYDNR--VIISGSSDATVRVWDVETGECIKTLIHHC 302 Query: 175 DDIMRLTQMN--------------TDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVS 312 + ++ L N D+ D ++ VL GH VN F IVS Sbjct: 303 EAVLHLRFANGIMVTCSKDRSIAVWDMVSPRDITIRRVLVGHRAAVNVVDFDDR--YIVS 360 Query: 313 GADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 + DR +K+W M+ + V TL GH ++C+ + + ++VS S D Sbjct: 361 ASGDRTIKVWSMDTLEF--VRTLAGHRRGIACLQYRGR--LVVSGSSD 404 Score = 46.2 bits (108), Expect = 5e-05 Identities = 45/159 (28%), Positives = 65/159 (40%), Gaps = 7/159 (4%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 ++W+ + V L GH + C + + LVVS S D T+R+WDI + Sbjct: 368 KVWSMDTLEFVRTLAGHRRGIACLQYRGR--LVVSGSSDNTIRLWDIHS----------- 414 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMN--- 351 V VLEGH+ V F IVSGA D ++K+W + Sbjct: 415 ----------------GVCLRVLEGHEELVRCIRFDEKR--IVSGAYDGKIKVWDLQAAL 456 Query: 352 DTKAWEVD----TLRGHMNNVSCVMFHAKQDIIVSNSED 456 D +A + +L H V + F Q IVS+S D Sbjct: 457 DPRALSSEICLCSLVQHTGRVFRLQFDDFQ--IVSSSHD 493 Score = 32.0 bits (71), Expect = 0.88 Identities = 17/51 (33%), Positives = 26/51 (50%) Frame = +1 Query: 304 IVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 IVSG D +K+W D + L GH +V C+ + + +I+S S D Sbjct: 235 IVSGLRDNTIKIWDRKDYSCSRI--LSGHTGSVLCLQYDNR--VIISGSSD 281
>WDR5_MOUSE (P61965) WD-repeat protein 5 (BMP2-induced 3-kb gene protein)| (WD-repeat protein BIG-3) Length = 334 Score = 72.8 bits (177), Expect = 5e-13 Identities = 48/171 (28%), Positives = 82/171 (47%), Gaps = 19/171 (11%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALR-KKTVSPAD 177 +IW+ S C+ L GH++YV C +F+P+ +L+VS S D++VR+WD+ + KT+ Sbjct: 112 KIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHS 171 Query: 178 DIMRLTQMNTD-------LFGGVDAV--------VKYVLEGHDRGVNWASFHPTLPLIVS 312 D + N D + G+ + +K +++ + V++ F P I++ Sbjct: 172 DPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILA 231 Query: 313 GADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFH---AKQDIIVSNSED 456 D +KLW + K + T GH N C+ + IVS SED Sbjct: 232 ATLDNTLKLWDYSKGKC--LKTYTGHKNEKYCIFANFSVTGGKWIVSGSED 280 Score = 61.6 bits (148), Expect = 1e-09 Identities = 36/141 (25%), Positives = 64/141 (45%) Frame = +1 Query: 40 LTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDIMRLTQMNTDLFG 219 L GH V F P + + S+S D+ +++W G Sbjct: 41 LAGHTKAVSSVKFSPNGEWLASSSADKLIKIW---------------------------G 73 Query: 220 GVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVDTLRGHMNN 399 D + + GH G++ ++ L+VS +DD+ +K+W ++ K + TL+GH N Sbjct: 74 AYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKC--LKTLKGHSNY 131 Query: 400 VSCVMFHAKQDIIVSNSEDKA 462 V C F+ + ++IVS S D++ Sbjct: 132 VFCCNFNPQSNLIVSGSFDES 152 Score = 55.8 bits (133), Expect = 6e-08 Identities = 40/152 (26%), Positives = 66/152 (43%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 +IW ++GH + ++ +L+VSAS D+T+++WD+ + Sbjct: 70 KIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSS----------- 118 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTK 360 L+GH V +F+P LIVSG+ D V++W + K Sbjct: 119 ----------------GKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGK 162 Query: 361 AWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 + TL H + VS V F+ +IVS+S D Sbjct: 163 C--LKTLPAHSDPVSAVHFNRDGSLIVSSSYD 192 Score = 44.7 bits (104), Expect = 1e-04 Identities = 23/75 (30%), Positives = 41/75 (54%) Frame = +1 Query: 235 VKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVM 414 +K+ L GH + V+ F P + S + D+ +K+W D K + T+ GH +S V Sbjct: 37 LKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEK--TISGHKLGISDVA 94 Query: 415 FHAKQDIIVSNSEDK 459 + + +++VS S+DK Sbjct: 95 WSSDSNLLVSASDDK 109 Score = 42.4 bits (98), Expect = 7e-04 Identities = 18/46 (39%), Positives = 30/46 (65%), Gaps = 2/46 (4%) Frame = +1 Query: 4 IWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASL--DQTVRVW 135 IWN Q++ V L GH V+ + HP E+++ SA+L D+T+++W Sbjct: 285 IWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLW 330
>WDR5_HUMAN (P61964) WD-repeat protein 5 (BMP2-induced 3-kb gene protein)| Length = 334 Score = 72.8 bits (177), Expect = 5e-13 Identities = 48/171 (28%), Positives = 82/171 (47%), Gaps = 19/171 (11%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALR-KKTVSPAD 177 +IW+ S C+ L GH++YV C +F+P+ +L+VS S D++VR+WD+ + KT+ Sbjct: 112 KIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHS 171 Query: 178 DIMRLTQMNTD-------LFGGVDAV--------VKYVLEGHDRGVNWASFHPTLPLIVS 312 D + N D + G+ + +K +++ + V++ F P I++ Sbjct: 172 DPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILA 231 Query: 313 GADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFH---AKQDIIVSNSED 456 D +KLW + K + T GH N C+ + IVS SED Sbjct: 232 ATLDNTLKLWDYSKGKC--LKTYTGHKNEKYCIFANFSVTGGKWIVSGSED 280 Score = 61.6 bits (148), Expect = 1e-09 Identities = 36/141 (25%), Positives = 64/141 (45%) Frame = +1 Query: 40 LTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDIMRLTQMNTDLFG 219 L GH V F P + + S+S D+ +++W G Sbjct: 41 LAGHTKAVSSVKFSPNGEWLASSSADKLIKIW---------------------------G 73 Query: 220 GVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVDTLRGHMNN 399 D + + GH G++ ++ L+VS +DD+ +K+W ++ K + TL+GH N Sbjct: 74 AYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKC--LKTLKGHSNY 131 Query: 400 VSCVMFHAKQDIIVSNSEDKA 462 V C F+ + ++IVS S D++ Sbjct: 132 VFCCNFNPQSNLIVSGSFDES 152 Score = 55.8 bits (133), Expect = 6e-08 Identities = 40/152 (26%), Positives = 66/152 (43%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 +IW ++GH + ++ +L+VSAS D+T+++WD+ + Sbjct: 70 KIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSS----------- 118 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTK 360 L+GH V +F+P LIVSG+ D V++W + K Sbjct: 119 ----------------GKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGK 162 Query: 361 AWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 + TL H + VS V F+ +IVS+S D Sbjct: 163 C--LKTLPAHSDPVSAVHFNRDGSLIVSSSYD 192 Score = 44.7 bits (104), Expect = 1e-04 Identities = 23/75 (30%), Positives = 41/75 (54%) Frame = +1 Query: 235 VKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVM 414 +K+ L GH + V+ F P + S + D+ +K+W D K + T+ GH +S V Sbjct: 37 LKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEK--TISGHKLGISDVA 94 Query: 415 FHAKQDIIVSNSEDK 459 + + +++VS S+DK Sbjct: 95 WSSDSNLLVSASDDK 109 Score = 42.4 bits (98), Expect = 7e-04 Identities = 18/46 (39%), Positives = 30/46 (65%), Gaps = 2/46 (4%) Frame = +1 Query: 4 IWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASL--DQTVRVW 135 IWN Q++ V L GH V+ + HP E+++ SA+L D+T+++W Sbjct: 285 IWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLW 330
>Y2800_ANASP (Q8YTC2) Hypothetical WD-repeat protein alr2800| Length = 1258 Score = 72.0 bits (175), Expect = 8e-13 Identities = 46/168 (27%), Positives = 77/168 (45%), Gaps = 15/168 (8%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI-GALRKKTVSPAD 177 ++W+ + C+ LTGH H V +FHP + + SAS D+T+++WDI +T++ Sbjct: 709 KLWSVRDGVCIKTLTGHEHEVFSVAFHPDGETLASASGDKTIKLWDIQDGTCLQTLTGHT 768 Query: 178 DIMRLTQM----NTDLFGGVDAVVKY----------VLEGHDRGVNWASFHPTLPLIVSG 315 D +R NT D +K L+ H V +F + SG Sbjct: 769 DWVRCVAFSPDGNTLASSAADHTIKLWDVSQGKCLRTLKSHTGWVRSVAFSADGQTLASG 828 Query: 316 ADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSEDK 459 + DR +K+W + + + T GH N+V + + I+VS S D+ Sbjct: 829 SGDRTIKIWNYHTGEC--LKTYIGHTNSVYSIAYSPDSKILVSGSGDR 874 Score = 70.9 bits (172), Expect = 2e-12 Identities = 45/169 (26%), Positives = 75/169 (44%), Gaps = 15/169 (8%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALR-KKTVSPAD 177 ++W+ Q TC+ LTGH +V C +F P + + S++ D T+++WD+ + +T+ Sbjct: 751 KLWDIQDGTCLQTLTGHTDWVRCVAFSPDGNTLASSAADHTIKLWDVSQGKCLRTLKSHT 810 Query: 178 DIMRLTQMNTD----LFGGVDAVVKY----------VLEGHDRGVNWASFHPTLPLIVSG 315 +R + D G D +K GH V ++ P ++VSG Sbjct: 811 GWVRSVAFSADGQTLASGSGDRTIKIWNYHTGECLKTYIGHTNSVYSIAYSPDSKILVSG 870 Query: 316 ADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSEDKA 462 + DR +KLW + TL GH N V V F + S D++ Sbjct: 871 SGDRTIKLWDCQTHIC--IKTLHGHTNEVCSVAFSPDGQTLACVSLDQS 917 Score = 65.1 bits (157), Expect = 9e-11 Identities = 44/168 (26%), Positives = 78/168 (46%), Gaps = 15/168 (8%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWD------IGALRKKT 162 ++WN + C+ L+ H+ ++ ++ P L+ SAS DQ+VR+WD +G LR + Sbjct: 1045 KLWNISTGQCLKTLSEHSDKILGMAWSPDGQLLASASADQSVRLWDCCTGRCVGILRGHS 1104 Query: 163 -------VSPADDIMRL--TQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSG 315 SP +I+ T ++ L GH V +F P ++ S Sbjct: 1105 NRVYSAIFSPNGEIIATCSTDQTVKIWDWQQGKCLKTLTGHTNWVFDIAFSPDGKILASA 1164 Query: 316 ADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSEDK 459 + D+ V++W +N K + GH + VS V F +++ S S+D+ Sbjct: 1165 SHDQTVRIWDVNTGKCHHICI--GHTHLVSSVAFSPDGEVVASGSQDQ 1210 Score = 63.9 bits (154), Expect = 2e-10 Identities = 32/124 (25%), Positives = 57/124 (45%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 +IW+WQ C+ LTGH ++V +F P ++ SAS DQTVR+WD+ + Sbjct: 1129 KIWDWQQGKCLKTLTGHTNWVFDIAFSPDGKILASASHDQTVRIWDVNTGK--------- 1179 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTK 360 ++ GH V+ +F P ++ SG+ D+ V++W + + Sbjct: 1180 ------------------CHHICIGHTHLVSSVAFSPDGEVVASGSQDQTVRIWNVKTGE 1221 Query: 361 AWEV 372 ++ Sbjct: 1222 CLQI 1225 Score = 63.5 bits (153), Expect = 3e-10 Identities = 47/168 (27%), Positives = 73/168 (43%), Gaps = 15/168 (8%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALR-KKTVSPAD 177 R+WN + C +L H +V FHP+ ++ + S D TV++W+I + KT+S Sbjct: 1003 RLWNISTGQCFQILLEHTDWVYAVVFHPQGKIIATGSADCTVKLWNISTGQCLKTLSEHS 1062 Query: 178 DIMRLTQMNTD----LFGGVDAVVKY----------VLEGHDRGVNWASFHPTLPLIVSG 315 D + + D D V+ +L GH V A F P +I + Sbjct: 1063 DKILGMAWSPDGQLLASASADQSVRLWDCCTGRCVGILRGHSNRVYSAIFSPNGEIIATC 1122 Query: 316 ADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSEDK 459 + D+ VK+W K + TL GH N V + F I+ S S D+ Sbjct: 1123 STDQTVKIWDWQQGKC--LKTLTGHTNWVFDIAFSPDGKILASASHDQ 1168 Score = 61.6 bits (148), Expect = 1e-09 Identities = 37/152 (24%), Positives = 64/152 (42%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 R+W +S + + GH+++V F P +++ S D+ V++W + Sbjct: 667 RVWEVKSGKLLLICRGHSNWVRFVVFSPDGEILASCGADENVKLWSVR------------ 714 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTK 360 D V L GH+ V +FHP + S + D+ +KLW + D Sbjct: 715 ---------------DGVCIKTLTGHEHEVFSVAFHPDGETLASASGDKTIKLWDIQDGT 759 Query: 361 AWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 + TL GH + V CV F + + S++ D Sbjct: 760 C--LQTLTGHTDWVRCVAFSPDGNTLASSAAD 789 Score = 61.2 bits (147), Expect = 1e-09 Identities = 45/167 (26%), Positives = 74/167 (44%), Gaps = 15/167 (8%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWD--IGALRKKTVSPA 174 ++W+ Q+ C+ L GH + V +F P + SLDQ+VR+W+ G K Sbjct: 877 KLWDCQTHICIKTLHGHTNEVCSVAFSPDGQTLACVSLDQSVRLWNCRTGQCLKAWYGNT 936 Query: 175 DDIMRLT---QMNTDLFGGVDAVV--------KYV--LEGHDRGVNWASFHPTLPLIVSG 315 D + + G D V KY+ LEGH + +F P + S Sbjct: 937 DWALPVAFSPDRQILASGSNDKTVKLWDWQTGKYISSLEGHTDFIYGIAFSPDSQTLASA 996 Query: 316 ADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 + D V+LW ++ + +++ L H + V V+FH + II + S D Sbjct: 997 STDSSVRLWNISTGQCFQI--LLEHTDWVYAVVFHPQGKIIATGSAD 1041 Score = 60.5 bits (145), Expect = 2e-09 Identities = 44/168 (26%), Positives = 73/168 (43%), Gaps = 15/168 (8%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI--GALRKKTVSPA 174 ++W+WQ+ ++ L GH ++ +F P + SAS D +VR+W+I G + + Sbjct: 961 KLWDWQTGKYISSLEGHTDFIYGIAFSPDSQTLASASTDSSVRLWNISTGQCFQILLEHT 1020 Query: 175 DDIMRLT---QMNTDLFGGVDAVVKY----------VLEGHDRGVNWASFHPTLPLIVSG 315 D + + Q G D VK L H + ++ P L+ S Sbjct: 1021 DWVYAVVFHPQGKIIATGSADCTVKLWNISTGQCLKTLSEHSDKILGMAWSPDGQLLASA 1080 Query: 316 ADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSEDK 459 + D+ V+LW + V LRGH N V +F +II + S D+ Sbjct: 1081 SADQSVRLWDCCTGRC--VGILRGHSNRVYSAIFSPNGEIIATCSTDQ 1126
>FBW1A_HUMAN (Q9Y297) F-box/WD-repeat protein 1A (F-box and WD-repeats protein| beta-TrCP) (E3RSIkappaB) (pIkappaBalpha-E3 receptor subunit) Length = 605 Score = 72.0 bits (175), Expect = 8e-13 Identities = 48/168 (28%), Positives = 78/168 (46%), Gaps = 16/168 (9%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI--GALRKKTVSPA 174 +IW+ + C +LTGH V+C + E ++++ S D TVRVWD+ G + + Sbjct: 326 KIWDKNTLECKRILTGHTGSVLCLQY--DERVIITGSSDSTVRVWDVNTGEMLNTLIHHC 383 Query: 175 DDIMRLTQMN--------------TDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVS 312 + ++ L N D+ D ++ VL GH VN F IVS Sbjct: 384 EAVLHLRFNNGMMVTCSKDRSIAVWDMASPTDITLRRVLVGHRAAVNVVDFDD--KYIVS 441 Query: 313 GADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 + DR +K+W N + V TL GH ++C+ + + ++VS S D Sbjct: 442 ASGDRTIKVW--NTSTCEFVRTLNGHKRGIACLQY--RDRLVVSGSSD 485 Score = 45.4 bits (106), Expect = 8e-05 Identities = 35/116 (30%), Positives = 49/116 (42%), Gaps = 2/116 (1%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI--GALRKKTVSPA 174 ++WN + V L GH + C + ++ LVVS S D T+R+WDI GA + Sbjct: 449 KVWNTSTCEFVRTLNGHKRGIACLQY--RDRLVVSGSSDNTIRLWDIECGACLR------ 500 Query: 175 DDIMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLW 342 VLEGH+ V F IVSGA D ++K+W Sbjct: 501 -----------------------VLEGHEELVRCIRFDNKR--IVSGAYDGKIKVW 531 Score = 40.0 bits (92), Expect = 0.003 Identities = 18/49 (36%), Positives = 27/49 (55%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGA 147 R+W+ + C+ VL GH V C F K +VS + D ++VWD+ A Sbjct: 489 RLWDIECGACLRVLEGHEELVRCIRFDNKR--IVSGAYDGKIKVWDLVA 535 Score = 31.6 bits (70), Expect = 1.2 Identities = 16/51 (31%), Positives = 27/51 (52%) Frame = +1 Query: 304 IVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 IVSG D +K+W N + + L GH +V C+ + + +I++ S D Sbjct: 316 IVSGLRDNTIKIWDKNTLECKRI--LTGHTGSVLCLQYDER--VIITGSSD 362
>TRCB_XENLA (Q91854) Beta-TrCP (Beta-transducin repeat-containing protein)| Length = 518 Score = 70.9 bits (172), Expect = 2e-12 Identities = 48/168 (28%), Positives = 77/168 (45%), Gaps = 16/168 (9%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI--GALRKKTVSPA 174 +IW+ + C VL GH V+C + E ++++ S D TVRVWD+ G + + Sbjct: 255 KIWDKNTLECKRVLMGHTGSVLCLQYD--ERVIITGSSDSTVRVWDVNTGEMLNTLIHHC 312 Query: 175 DDIMRLTQMN--------------TDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVS 312 + ++ L N D+ D ++ VL GH VN F IVS Sbjct: 313 EAVLHLRFNNGMMVTCSKDRSIAVWDMASATDITLRRVLVGHRAAVNVVDFDD--KYIVS 370 Query: 313 GADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 + DR +K+W N + V TL GH ++C+ + + ++VS S D Sbjct: 371 ASGDRTIKVW--NTSTCEFVRTLNGHKRGIACLQY--RDRLVVSGSSD 414 Score = 45.4 bits (106), Expect = 8e-05 Identities = 35/116 (30%), Positives = 49/116 (42%), Gaps = 2/116 (1%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI--GALRKKTVSPA 174 ++WN + V L GH + C + ++ LVVS S D T+R+WDI GA + Sbjct: 378 KVWNTSTCEFVRTLNGHKRGIACLQY--RDRLVVSGSSDNTIRLWDIECGACLR------ 429 Query: 175 DDIMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLW 342 VLEGH+ V F IVSGA D ++K+W Sbjct: 430 -----------------------VLEGHEELVRCIRFDNKR--IVSGAYDGKIKVW 460 Score = 40.0 bits (92), Expect = 0.003 Identities = 18/49 (36%), Positives = 27/49 (55%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGA 147 R+W+ + C+ VL GH V C F K +VS + D ++VWD+ A Sbjct: 418 RLWDIECGACLRVLEGHEELVRCIRFDNKR--IVSGAYDGKIKVWDLVA 464 Score = 32.0 bits (71), Expect = 0.88 Identities = 17/51 (33%), Positives = 27/51 (52%) Frame = +1 Query: 304 IVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 IVSG D +K+W N + V L GH +V C+ + + +I++ S D Sbjct: 245 IVSGLRDNTIKIWDKNTLECKRV--LMGHTGSVLCLQYDER--VIITGSSD 291
>GBLP_LEIMA (Q25306) Guanine nucleotide-binding protein beta subunit-like| protein (Antigen LACK) Length = 312 Score = 69.3 bits (168), Expect = 5e-12 Identities = 46/159 (28%), Positives = 78/159 (49%), Gaps = 18/159 (11%) Frame = +1 Query: 40 LTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI--GALRKKTVSPADDIMRLTQMNTD- 210 L GH +V C S D ++AS D+++R+WD+ G ++K + D++ + D Sbjct: 61 LEGHTGFVSCVSLAHATDYALTASWDRSIRMWDLRNGQCQRKFLKHTKDVLAVAFSPDDR 120 Query: 211 --LFGGVDAVVK-----------YVLEGHDRGVNWASFHPTL--PLIVSGADDRQVKLWR 345 + G D V++ ++ +GH+ V+ F P+L P++VSG+ D +K+W Sbjct: 121 LIVSAGRDNVIRVWNVAGECMHEFLRDGHEDWVSSICFSPSLEHPIVVSGSWDNTIKVWN 180 Query: 346 MNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSEDKA 462 +N K TL+GH N VS V + S +D A Sbjct: 181 VNGGKCER--TLKGHSNYVSTVTVSPDGSLCASGGKDGA 217 Score = 35.4 bits (80), Expect = 0.080 Identities = 14/47 (29%), Positives = 21/47 (44%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI 141 ++WN C L GH++YV + P L S D +WD+ Sbjct: 177 KVWNVNGGKCERTLKGHSNYVSTVTVSPDGSLCASGGKDGAALLWDL 223
>GBLP_LEIIN (P62884) Guanine nucleotide-binding protein beta subunit-like| protein (Antigen LACK) (LiP36) (p36Li) Length = 312 Score = 69.3 bits (168), Expect = 5e-12 Identities = 46/159 (28%), Positives = 78/159 (49%), Gaps = 18/159 (11%) Frame = +1 Query: 40 LTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI--GALRKKTVSPADDIMRLTQMNTD- 210 L GH +V C S D ++AS D+++R+WD+ G ++K + D++ + D Sbjct: 61 LEGHTGFVSCVSLAHATDYALTASWDRSIRMWDLRNGQCQRKFLKHTKDVLAVAFSPDDR 120 Query: 211 --LFGGVDAVVK-----------YVLEGHDRGVNWASFHPTL--PLIVSGADDRQVKLWR 345 + G D V++ ++ +GH+ V+ F P+L P++VSG+ D +K+W Sbjct: 121 LIVSAGRDNVIRVWNVAGECMHEFLRDGHEDWVSSICFSPSLEHPIVVSGSWDNTIKVWN 180 Query: 346 MNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSEDKA 462 +N K TL+GH N VS V + S +D A Sbjct: 181 VNGGKCER--TLKGHSNYVSTVTVSPDGSLCASGGKDGA 217 Score = 35.4 bits (80), Expect = 0.080 Identities = 14/47 (29%), Positives = 21/47 (44%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI 141 ++WN C L GH++YV + P L S D +WD+ Sbjct: 177 KVWNVNGGKCERTLKGHSNYVSTVTVSPDGSLCASGGKDGAALLWDL 223
>GBLP_LEICH (P62883) Guanine nucleotide-binding protein beta subunit-like| protein (Antigen LACK) Length = 312 Score = 69.3 bits (168), Expect = 5e-12 Identities = 46/159 (28%), Positives = 78/159 (49%), Gaps = 18/159 (11%) Frame = +1 Query: 40 LTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI--GALRKKTVSPADDIMRLTQMNTD- 210 L GH +V C S D ++AS D+++R+WD+ G ++K + D++ + D Sbjct: 61 LEGHTGFVSCVSLAHATDYALTASWDRSIRMWDLRNGQCQRKFLKHTKDVLAVAFSPDDR 120 Query: 211 --LFGGVDAVVK-----------YVLEGHDRGVNWASFHPTL--PLIVSGADDRQVKLWR 345 + G D V++ ++ +GH+ V+ F P+L P++VSG+ D +K+W Sbjct: 121 LIVSAGRDNVIRVWNVAGECMHEFLRDGHEDWVSSICFSPSLEHPIVVSGSWDNTIKVWN 180 Query: 346 MNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSEDKA 462 +N K TL+GH N VS V + S +D A Sbjct: 181 VNGGKCER--TLKGHSNYVSTVTVSPDGSLCASGGKDGA 217 Score = 35.4 bits (80), Expect = 0.080 Identities = 14/47 (29%), Positives = 21/47 (44%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI 141 ++WN C L GH++YV + P L S D +WD+ Sbjct: 177 KVWNVNGGKCERTLKGHSNYVSTVTVSPDGSLCASGGKDGAALLWDL 223
>KTNB1_BRARE (Q7ZUV2) Katanin p80 WD40-containing subunit B1 homolog| Length = 694 Score = 67.4 bits (163), Expect = 2e-11 Identities = 49/171 (28%), Positives = 76/171 (44%), Gaps = 19/171 (11%) Frame = +1 Query: 4 IWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALR--------KK 159 IW C+ LTGH V C F+ E+ VV+ SL ++R+WD+ A + K Sbjct: 47 IWAVSKPNCIMSLTGHTSAVGCIQFNSSEERVVAGSLSGSLRLWDLEAAKILRTLMGHKA 106 Query: 160 TVSPADDIMRLTQMNTDL-FGGVDAVVK----------YVLEGHDRGVNWASFHPTLPLI 306 ++S D M L G VD+ +K + +GH + V +F P + Sbjct: 107 SISSLD----FHPMGEYLASGSVDSNIKLWDVRRKGCVFRYKGHTQAVRCLAFSPDGKWL 162 Query: 307 VSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSEDK 459 S +DD VKLW + K + H + V+ V FH + ++ S S D+ Sbjct: 163 ASASDDSTVKLWDLIAGKM--ITEFTSHTSAVNVVQFHPNEYLLASGSADR 211 Score = 59.3 bits (142), Expect = 5e-09 Identities = 42/152 (27%), Positives = 62/152 (40%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 ++W+ + + CV GH V C +F P + SAS D TV++WD+ A + T Sbjct: 130 KLWDVRRKGCVFRYKGHTQAVRCLAFSPDGKWLASASDDSTVKLWDLIAGKMIT------ 183 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTK 360 H VN FHP L+ SG+ DR VKLW + K Sbjct: 184 ---------------------EFTSHTSAVNVVQFHPNEYLLASGSADRTVKLWDLE--K 220 Query: 361 AWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 + + G V V+F+ + S SE+ Sbjct: 221 FNMIGSSEGETGVVRSVLFNPDGSCLYSGSEN 252
>WDS_DROME (Q9V3J8) Protein will die slowly| Length = 361 Score = 67.4 bits (163), Expect = 2e-11 Identities = 45/171 (26%), Positives = 80/171 (46%), Gaps = 19/171 (11%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALR-KKTVSPAD 177 ++W + + L GH++YV C +F+P+ +L+VS S D++VR+WD+ + KT+ Sbjct: 139 KVWELSTGKSLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVRTGKCLKTLPAHS 198 Query: 178 DIMRLTQMNTD-------LFGGVDAV--------VKYVLEGHDRGVNWASFHPTLPLIVS 312 D + N D + G+ + +K +++ + V++ F P I++ Sbjct: 199 DPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILA 258 Query: 313 GADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFH---AKQDIIVSNSED 456 D +KLW + K + T GH N C+ + IVS SED Sbjct: 259 ATLDNTLKLWDYSKGKC--LKTYTGHKNEKYCIFANFSVTGGKWIVSGSED 307 Score = 65.1 bits (157), Expect = 9e-11 Identities = 37/141 (26%), Positives = 66/141 (46%) Frame = +1 Query: 40 LTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDIMRLTQMNTDLFG 219 L GH V F P + + S+S D+ +++W G Sbjct: 68 LAGHTKAVSAVKFSPNGEWLASSSADKLIKIW---------------------------G 100 Query: 220 GVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVDTLRGHMNN 399 D + + GH G++ ++ L+VSG+DD+ +K+W ++ K+ + TL+GH N Sbjct: 101 AYDGKFEKTISGHKLGISDVAWSSDSRLLVSGSDDKTLKVWELSTGKS--LKTLKGHSNY 158 Query: 400 VSCVMFHAKQDIIVSNSEDKA 462 V C F+ + ++IVS S D++ Sbjct: 159 VFCCNFNPQSNLIVSGSFDES 179 Score = 52.0 bits (123), Expect = 8e-07 Identities = 39/152 (25%), Positives = 64/152 (42%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 +IW ++GH + ++ L+VS S D+T++VW++ + Sbjct: 97 KIWGAYDGKFEKTISGHKLGISDVAWSSDSRLLVSGSDDKTLKVWELSTGKSLK------ 150 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTK 360 L+GH V +F+P LIVSG+ D V++W + K Sbjct: 151 ---------------------TLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVRTGK 189 Query: 361 AWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 + TL H + VS V F+ +IVS+S D Sbjct: 190 C--LKTLPAHSDPVSAVHFNRDGSLIVSSSYD 219 Score = 47.4 bits (111), Expect = 2e-05 Identities = 20/46 (43%), Positives = 31/46 (67%), Gaps = 2/46 (4%) Frame = +1 Query: 4 IWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASL--DQTVRVW 135 IWN QS+ V L GH V+C + HP E+++ SA+L D+T+++W Sbjct: 312 IWNLQSKEVVQKLQGHTDTVLCTACHPTENIIASAALENDKTIKLW 357 Score = 44.3 bits (103), Expect = 2e-04 Identities = 23/75 (30%), Positives = 40/75 (53%) Frame = +1 Query: 235 VKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVM 414 +K+ L GH + V+ F P + S + D+ +K+W D K + T+ GH +S V Sbjct: 64 LKFTLAGHTKAVSAVKFSPNGEWLASSSADKLIKIWGAYDGKFEK--TISGHKLGISDVA 121 Query: 415 FHAKQDIIVSNSEDK 459 + + ++VS S+DK Sbjct: 122 WSSDSRLLVSGSDDK 136 Score = 40.8 bits (94), Expect = 0.002 Identities = 37/136 (27%), Positives = 57/136 (41%), Gaps = 21/136 (15%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGH-NHYVMCASFHPKEDLVVSASLDQTVRVWDIGALR-KKTVSPA 174 RIW+ S C+ L N V F P +++A+LD T+++WD + KT + Sbjct: 223 RIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGH 282 Query: 175 DDIMRLTQMNTDLFGGVDAV-----------------VKYVLEGHDRGVNWASFHPTLPL 303 + N + GG V V L+GH V + HPT + Sbjct: 283 KNEKYCIFANFSVTGGKWIVSGSEDNMVYIWNLQSKEVVQKLQGHTDTVLCTACHPTENI 342 Query: 304 IVSGA--DDRQVKLWR 345 I S A +D+ +KLW+ Sbjct: 343 IASAALENDKTIKLWK 358
>SPG16_MOUSE (Q8K450) Sperm-associated antigen 16 protein (PF20 protein homolog)| Length = 639 Score = 66.6 bits (161), Expect = 3e-11 Identities = 40/148 (27%), Positives = 64/148 (43%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 ++W+ C L GHNH V ++H D V SASLD T ++WD+ + R Sbjct: 427 KLWDLNKGECTLTLEGHNHAVWSCTWHSCGDFVASASLDMTSKIWDVNSER--------- 477 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTK 360 +Y L GH VN F P ++++ + D+ + +W K Sbjct: 478 ------------------CRYTLYGHTDSVNSIEFFPFSNILLTASADKTLSVWDARTGK 519 Query: 361 AWEVDTLRGHMNNVSCVMFHAKQDIIVS 444 + +L GHM++V+ F + II S Sbjct: 520 CEQ--SLYGHMHSVNDATFTPRGHIIAS 545 Score = 41.2 bits (95), Expect = 0.001 Identities = 37/136 (27%), Positives = 54/136 (39%) Frame = +1 Query: 49 HNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDIMRLTQMNTDLFGGVD 228 H V C HP D ++S S D R+W + + L Q N L G Sbjct: 359 HELPVSCIVMHPCRDYLISCSED---RLWKM--------------VGLPQGNVLLTGS-- 399 Query: 229 AVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSC 408 GH ++ FHP+ + + + D +KLW +N K TL GH + V Sbjct: 400 --------GHTDWLSGCCFHPSGSKLATSSGDSTIKLWDLN--KGECTLTLEGHNHAVWS 449 Query: 409 VMFHAKQDIIVSNSED 456 +H+ D + S S D Sbjct: 450 CTWHSCGDFVASASLD 465 Score = 35.8 bits (81), Expect = 0.061 Identities = 31/131 (23%), Positives = 50/131 (38%), Gaps = 18/131 (13%) Frame = +1 Query: 4 IWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGAL---RKKTVSPA 174 +W+ ++ C L GH H V A+F P+ ++ S ++WD L V P+ Sbjct: 512 VWDARTGKCEQSLYGHMHSVNDATFTPRGHIIASCDARGVTKLWDFRKLIPIVSIDVGPS 571 Query: 175 DDIMRLTQMNTDLFGGVDAVVK---------------YVLEGHDRGVNWASFHPTLPLIV 309 ++N D G V A + L GH+ V+ F + Sbjct: 572 SG----NEVNFDQSGRVLAQASANGIIHLLDLKSGQIHKLVGHESEVHSVVFSHLGENLY 627 Query: 310 SGADDRQVKLW 342 SG D ++LW Sbjct: 628 SGGSDGTIRLW 638 Score = 28.5 bits (62), Expect = 9.7 Identities = 14/35 (40%), Positives = 22/35 (62%), Gaps = 1/35 (2%) Frame = +1 Query: 382 RGHMNNVSCVMFHAKQDIIVSNSEDKAFAS-GMPQ 483 R H VSC++ H +D ++S SED+ + G+PQ Sbjct: 357 RLHELPVSCIVMHPCRDYLISCSEDRLWKMVGLPQ 391
>YH92_CAEEL (Q23256) Hypothetical WD-repeat protein ZC302.2| Length = 501 Score = 66.2 bits (160), Expect = 4e-11 Identities = 49/171 (28%), Positives = 78/171 (45%), Gaps = 19/171 (11%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI--GALRKKTVSPA 174 +I++ S C+ + GH +YV C SF+P+ L+ SA D+TVRVWD G K + + Sbjct: 280 KIFDVISGACLRTMRGHTNYVFCCSFNPQSSLIASAGFDETVRVWDFKTGLCVKCIPAHS 339 Query: 175 DDIMRLT------QMNTDLFGGVDAV--------VKYVLEGHDRGVNWASFHPTLPLIVS 312 D I ++ M T + G V +K +++ V + F P ++S Sbjct: 340 DPITSISYNHDGNTMATSSYDGCIRVWDAASGSCLKTLVDTDHAPVTFVCFSPNGKYLLS 399 Query: 313 GADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDI---IVSNSED 456 D +KLW + KA + GH N C+ + + I+S SED Sbjct: 400 AQLDSSLKLW--DPKKAKPLKYYNGHKNKKYCLFANMSVPLGKHIISGSED 448 Score = 44.3 bits (103), Expect = 2e-04 Identities = 37/138 (26%), Positives = 59/138 (42%), Gaps = 21/138 (15%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHY-VMCASFHPKEDLVVSASLDQTVRVWDI----------GA 147 R+W+ S +C+ L +H V F P ++SA LD ++++WD G Sbjct: 364 RVWDAASGSCLKTLVDTDHAPVTFVCFSPNGKYLLSAQLDSSLKLWDPKKAKPLKYYNGH 423 Query: 148 LRKK-------TVSPADDIMRLTQMNTDLFGGVDAV-VKYVLEGHDRGVNWASFHPTLPL 303 KK +V I+ ++ L + + +LEGH V HPTL + Sbjct: 424 KNKKYCLFANMSVPLGKHIISGSEDGRILVWSIQTKQIVQILEGHTTPVLATDSHPTLNI 483 Query: 304 IVSGA--DDRQVKLWRMN 351 I SG D +++WR N Sbjct: 484 IASGGLEPDNVIRIWRRN 501 Score = 40.4 bits (93), Expect = 0.002 Identities = 33/143 (23%), Positives = 53/143 (37%) Frame = +1 Query: 31 VAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDIMRLTQMNTD 210 V ++GH V F + + S D+ ++VW+ Sbjct: 206 VKTISGHTKSVSVIKFSYCGKYLGTGSADKQIKVWNT----------------------- 242 Query: 211 LFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVDTLRGH 390 VD L H G+N S+ I S +DD VK++ + + T+RGH Sbjct: 243 ----VDMTYLQTLASHQLGINDFSWSSNSQFIASASDDTTVKIFDVISGAC--LRTMRGH 296 Query: 391 MNNVSCVMFHAKQDIIVSNSEDK 459 N V C F+ + +I S D+ Sbjct: 297 TNYVFCCSFNPQSSLIASAGFDE 319 Score = 37.4 bits (85), Expect = 0.021 Identities = 29/152 (19%), Positives = 55/152 (36%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 ++WN T + L H + S+ + SAS D TV+++D+ Sbjct: 238 KVWNTVDMTYLQTLASHQLGINDFSWSSNSQFIASASDDTTVKIFDV------------- 284 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTK 360 + + GH V SF+P LI S D V++W Sbjct: 285 --------------ISGACLRTMRGHTNYVFCCSFNPQSSLIASAGFDETVRVWDFKTGL 330 Query: 361 AWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 V + H + ++ + ++ + + ++S D Sbjct: 331 C--VKCIPAHSDPITSISYNHDGNTMATSSYD 360 Score = 35.4 bits (80), Expect = 0.080 Identities = 14/46 (30%), Positives = 25/46 (54%), Gaps = 2/46 (4%) Frame = +1 Query: 4 IWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASL--DQTVRVW 135 +W+ Q++ V +L GH V+ HP +++ S L D +R+W Sbjct: 453 VWSIQTKQIVQILEGHTTPVLATDSHPTLNIIASGGLEPDNVIRIW 498
>HETE1_PODAN (Q00808) Vegetatible incompatibility protein HET-E-1| Length = 1356 Score = 65.5 bits (158), Expect = 7e-11 Identities = 47/169 (27%), Positives = 74/169 (43%), Gaps = 16/169 (9%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGA----------- 147 +IW+ S T L GH V +F P + V S S D+T+++WD + Sbjct: 866 KIWDTASGTGTQTLEGHGGSVWSVAFSPDRERVASGSDDKTIKIWDAASGTCTQTLEGHG 925 Query: 148 LRKKTVSPADDIMRLTQMNTD----LFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSG 315 R ++V+ + D R+ + D ++ LEGH V +F P + SG Sbjct: 926 GRVQSVAFSPDGQRVASGSDDHTIKIWDAASGTCTQTLEGHGSSVLSVAFSPDGQRVASG 985 Query: 316 ADDRQVKLWRMNDTKAWE-VDTLRGHMNNVSCVMFHAKQDIIVSNSEDK 459 + D+ +K+W DT + TL GH +V V F + S S+DK Sbjct: 986 SGDKTIKIW---DTASGTCTQTLEGHGGSVWSVAFSPDGQRVASGSDDK 1031 Score = 64.3 bits (155), Expect = 2e-10 Identities = 47/168 (27%), Positives = 71/168 (42%), Gaps = 16/168 (9%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGA----------- 147 +IW+ S TC L GH V +F P V S S D T+++WD + Sbjct: 908 KIWDAASGTCTQTLEGHGGRVQSVAFSPDGQRVASGSDDHTIKIWDAASGTCTQTLEGHG 967 Query: 148 LRKKTVSPADDIMRLTQMNTD----LFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSG 315 +V+ + D R+ + D ++ LEGH V +F P + SG Sbjct: 968 SSVLSVAFSPDGQRVASGSGDKTIKIWDTASGTCTQTLEGHGGSVWSVAFSPDGQRVASG 1027 Query: 316 ADDRQVKLWRMNDTKAWE-VDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 +DD+ +K+W DT + TL GH V V+F + S S+D Sbjct: 1028 SDDKTIKIW---DTASGTCTQTLEGHGGWVQSVVFSPDGQRVASGSDD 1072 Score = 63.9 bits (154), Expect = 2e-10 Identities = 48/170 (28%), Positives = 68/170 (40%), Gaps = 18/170 (10%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI------------- 141 +IW+ S TC L GH V +F P V S S+D T+++WD Sbjct: 1076 KIWDAVSGTCTQTLEGHGDSVWSVAFSPDGQRVASGSIDGTIKIWDAASGTCTQTLEGHG 1135 Query: 142 GALRKKTVSPADDIMRLTQMNTD----LFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIV 309 G + SP D R+ + D ++ LEGH V +F P + Sbjct: 1136 GWVHSVAFSP--DGQRVASGSIDGTIKIWDAASGTCTQTLEGHGGWVQSVAFSPDGQRVA 1193 Query: 310 SGADDRQVKLWRMNDTKAWE-VDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 SG+ D+ +K+W DT + TL GH V V F + S S D Sbjct: 1194 SGSSDKTIKIW---DTASGTCTQTLEGHGGWVQSVAFSPDGQRVASGSSD 1240 Score = 57.4 bits (137), Expect = 2e-08 Identities = 45/168 (26%), Positives = 66/168 (39%), Gaps = 17/168 (10%) Frame = +1 Query: 7 WNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI-------------GA 147 WN C L GH V+ +F V S S D+T+++WD G+ Sbjct: 830 WN----ACTQTLEGHGSSVLSVAFSADGQRVASGSDDKTIKIWDTASGTGTQTLEGHGGS 885 Query: 148 LRKKTVSPADDIMRLTQMNTD----LFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSG 315 + SP D R+ + D ++ LEGH V +F P + SG Sbjct: 886 VWSVAFSP--DRERVASGSDDKTIKIWDAASGTCTQTLEGHGGRVQSVAFSPDGQRVASG 943 Query: 316 ADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSEDK 459 +DD +K+W + TL GH ++V V F + S S DK Sbjct: 944 SDDHTIKIW--DAASGTCTQTLEGHGSSVLSVAFSPDGQRVASGSGDK 989 Score = 44.7 bits (104), Expect = 1e-04 Identities = 18/46 (39%), Positives = 25/46 (54%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWD 138 +IW+ S TC L GH +V +F P V S S D T+++WD Sbjct: 1202 KIWDTASGTCTQTLEGHGGWVQSVAFSPDGQRVASGSSDNTIKIWD 1247
>KTNB1_STRPU (O61585) Katanin p80 WD40-containing subunit B1 (Katanin p80| subunit B1) (p80 katanin) Length = 690 Score = 65.5 bits (158), Expect = 7e-11 Identities = 39/153 (25%), Positives = 66/153 (43%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 +I++ + V LTGH + + C FHP + V S S D V++WD+ RK + Sbjct: 84 KIYDLEPAKIVRTLTGHRNSIRCMDFHPFGEFVASGSTDTNVKLWDV--RRKGCI----- 136 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTK 360 Y +GH VN F P +V+ ++D +KLW + K Sbjct: 137 --------------------YTYKGHSDQVNMIKFSPDGKWLVTASEDTTIKLWDLTMGK 176 Query: 361 AWEVDTLRGHMNNVSCVMFHAKQDIIVSNSEDK 459 ++ + H V+ + FH + ++ S S D+ Sbjct: 177 LFQ--EFKNHTGGVTGIEFHPNEFLLASGSSDR 207
>LIS1_CAEEL (Q9NDC9) Lissencephaly-1 homolog (Pronuclear migration abnormal| protein 1) Length = 404 Score = 64.3 bits (155), Expect = 2e-10 Identities = 52/184 (28%), Positives = 83/184 (45%), Gaps = 31/184 (16%) Frame = +1 Query: 1 RIWNW-QSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIG-ALRKKTVSPA 174 ++W++ Q+ C+ L GH H V +F P D V+SAS D T++ WDI T Sbjct: 173 KLWDFGQTYDCLKSLKGHEHTVSSVTFLPTGDFVLSASRDHTIKQWDISTGYCVYTFRGH 232 Query: 175 DDIMRLTQMNTD--LF--GGVDAVV----------KYVLEGHDRGVNWASFHP------- 291 +D +R+ +++ D LF +D V K VL H+ V + P Sbjct: 233 NDWVRMIRISNDGTLFASASLDQTVTVWSFATKSAKLVLRDHEHAVECVEWAPDTAYTNV 292 Query: 292 --------TLPLIVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSN 447 + ++ SG+ DR +K W +N + TL H N V + FH K ++S Sbjct: 293 TGQQPEGNSTHILFSGSRDRSIKAWNINTGDV--LFTLLAHENWVRGLAFHPKGKYLISV 350 Query: 448 SEDK 459 ++DK Sbjct: 351 ADDK 354 Score = 58.9 bits (141), Expect = 7e-09 Identities = 46/180 (25%), Positives = 71/180 (39%), Gaps = 30/180 (16%) Frame = +1 Query: 7 WNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTV------- 165 W+ + CV GHN +V L SASLDQTV VW K V Sbjct: 218 WDISTGYCVYTFRGHNDWVRMIRISNDGTLFASASLDQTVTVWSFATKSAKLVLRDHEHA 277 Query: 166 ------SPADDIMRLTQMNTD------LFGGV-DAVVK----------YVLEGHDRGVNW 276 +P +T + LF G D +K + L H+ V Sbjct: 278 VECVEWAPDTAYTNVTGQQPEGNSTHILFSGSRDRSIKAWNINTGDVLFTLLAHENWVRG 337 Query: 277 ASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 +FHP ++S ADD+ +++W ++ + + + H + VS V FH +++ S D Sbjct: 338 LAFHPKGKYLISVADDKTLRVWELSAQRC--MKAIEAHEHFVSTVAFHQTSPFVITGSVD 395 Score = 53.5 bits (127), Expect = 3e-07 Identities = 28/114 (24%), Positives = 50/114 (43%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 + WN + + L H ++V +FHPK ++S + D+T+RVW++ A R Sbjct: 315 KAWNINTGDVLFTLLAHENWVRGLAFHPKGKYLISVADDKTLRVWELSAQR--------- 365 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLW 342 +E H+ V+ +FH T P +++G+ D K+W Sbjct: 366 ------------------CMKAIEAHEHFVSTVAFHQTSPFVITGSVDMSCKVW 401 Score = 50.4 bits (119), Expect = 2e-06 Identities = 43/157 (27%), Positives = 69/157 (43%), Gaps = 17/157 (10%) Frame = +1 Query: 40 LTGHNHYVMCASFHPKEDLVVSASLDQTVRVWD--IGALRKKTVSPADDI---------M 186 LTGH + FHP ++ S S D T++VWD G L + D + Sbjct: 102 LTGHRLPITRVIFHPLWTIMASCSEDATIKVWDYETGQLERTLKGHTDAVNDIAIDAAGK 161 Query: 187 RLTQMNTDL------FGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRM 348 +L ++DL FG +K L+GH+ V+ +F PT ++S + D +K W + Sbjct: 162 QLVSCSSDLSIKLWDFGQTYDCLK-SLKGHEHTVSSVTFLPTGDFVLSASRDHTIKQWDI 220 Query: 349 NDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSEDK 459 + + V T RGH + V + + S S D+ Sbjct: 221 --STGYCVYTFRGHNDWVRMIRISNDGTLFASASLDQ 255 Score = 42.7 bits (99), Expect = 5e-04 Identities = 13/46 (28%), Positives = 26/46 (56%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWD 138 R+W ++ C+ + H H+V +FH V++ S+D + +VW+ Sbjct: 357 RVWELSAQRCMKAIEAHEHFVSTVAFHQTSPFVITGSVDMSCKVWE 402
>KTNB1_ARATH (Q8H0T9) Katanin p80 WD40-containing subunit B1 homolog 1| Length = 837 Score = 63.9 bits (154), Expect = 2e-10 Identities = 40/153 (26%), Positives = 64/153 (41%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 ++W+ + V LTGH + FHP + S SLD +++WDI RKK Sbjct: 84 KLWDLEEAKIVRTLTGHRSNCISVDFHPFGEFFASGSLDTNLKIWDI---RKKGCI---- 136 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTK 360 + +GH RGVN F P +VSG +D VK+W + K Sbjct: 137 --------------------HTYKGHTRGVNVLRFTPDGRWVVSGGEDNIVKVWDLTAGK 176 Query: 361 AWEVDTLRGHMNNVSCVMFHAKQDIIVSNSEDK 459 + + H + + FH + ++ + S D+ Sbjct: 177 L--LTEFKSHEGQIQSLDFHPHEFLLATGSADR 207 Score = 36.2 bits (82), Expect = 0.047 Identities = 13/47 (27%), Positives = 24/47 (51%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI 141 ++W+ + + H + FHP E L+ + S D+TV+ WD+ Sbjct: 168 KVWDLTAGKLLTEFKSHEGQIQSLDFHPHEFLLATGSADRTVKFWDL 214
>KTNB1_MOUSE (Q8BG40) Katanin p80 WD40-containing subunit B1 (Katanin p80| subunit B1) (p80 katanin) Length = 658 Score = 63.5 bits (153), Expect = 3e-10 Identities = 42/153 (27%), Positives = 63/153 (41%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 R+W+ ++ + L GH + FHP + V S S D +++WDI R+K Sbjct: 88 RVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDI---RRK------- 137 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTK 360 V +Y GH + V F P + S ADD VKLW + K Sbjct: 138 ---------------GCVFRY--RGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGK 180 Query: 361 AWEVDTLRGHMNNVSCVMFHAKQDIIVSNSEDK 459 + GH V+ V FH + ++ S S D+ Sbjct: 181 M--MSEFPGHTGPVNVVEFHPNEYLLASGSSDR 211 Score = 58.9 bits (141), Expect = 7e-09 Identities = 39/152 (25%), Positives = 62/152 (40%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 ++W+ + + CV GH+ V C F P + SA+ D TV++WD+ A + + P Sbjct: 130 KLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFP--- 186 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTK 360 GH VN FHP L+ SG+ DR ++ W + K Sbjct: 187 ------------------------GHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLE--K 220 Query: 361 AWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 V + G V V+F+ + S +D Sbjct: 221 FQVVSCIEGEPGPVRSVLFNPDGCCLYSGCQD 252 Score = 33.9 bits (76), Expect = 0.23 Identities = 16/51 (31%), Positives = 29/51 (56%) Frame = +1 Query: 301 LIVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSE 453 L+ +G DD +V LW +N + +L GH + V V + +++IV+ S+ Sbjct: 35 LLATGGDDCRVNLWSINKPNC--IMSLTGHTSPVESVRLNTPEELIVAGSQ 83
>KTNB1_HUMAN (Q9BVA0) Katanin p80 WD40-containing subunit B1 (Katanin p80| subunit B1) (p80 katanin) Length = 655 Score = 63.5 bits (153), Expect = 3e-10 Identities = 42/153 (27%), Positives = 63/153 (41%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 R+W+ ++ + L GH + FHP + V S S D +++WDI R+K Sbjct: 88 RVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDI---RRK------- 137 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTK 360 V +Y GH + V F P + S ADD VKLW + K Sbjct: 138 ---------------GCVFRY--RGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGK 180 Query: 361 AWEVDTLRGHMNNVSCVMFHAKQDIIVSNSEDK 459 + GH V+ V FH + ++ S S D+ Sbjct: 181 M--MSEFPGHTGPVNVVEFHPNEYLLASGSSDR 211 Score = 58.9 bits (141), Expect = 7e-09 Identities = 39/152 (25%), Positives = 62/152 (40%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 ++W+ + + CV GH+ V C F P + SA+ D TV++WD+ A + + P Sbjct: 130 KLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFP--- 186 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTK 360 GH VN FHP L+ SG+ DR ++ W + K Sbjct: 187 ------------------------GHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLE--K 220 Query: 361 AWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 V + G V V+F+ + S +D Sbjct: 221 FQVVSCIEGEPGPVRSVLFNPDGCCLYSGCQD 252 Score = 33.9 bits (76), Expect = 0.23 Identities = 16/51 (31%), Positives = 29/51 (56%) Frame = +1 Query: 301 LIVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSE 453 L+ +G DD +V LW +N + +L GH + V V + +++IV+ S+ Sbjct: 35 LLATGGDDCRVNLWSINKPNC--IMSLTGHTSPVESVRLNTPEELIVAGSQ 83
>YKY4_CAEEL (Q17963) Hypothetical WD-repeat protein C14B1.4| Length = 376 Score = 63.5 bits (153), Expect = 3e-10 Identities = 47/158 (29%), Positives = 73/158 (46%), Gaps = 19/158 (12%) Frame = +1 Query: 40 LTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI-GALRKKTVSPADDIMRLTQMNTD-- 210 L GHN+YV C +F+P+ LVVS S D++VR+WD+ + KT+ D + N D Sbjct: 167 LKGHNNYVFCCNFNPQSSLVVSGSFDESVRIWDVKTGMCIKTLPAHSDPVSAVSFNRDGS 226 Query: 211 --LFGGVDAVV-----------KYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMN 351 G D +V K +++ + V + F P I++ D +KLW + Sbjct: 227 LIASGSYDGLVRIWDTANGQCIKTLVDDENPPVAFVKFSPNGKYILASNLDSTLKLWDFS 286 Query: 352 DTKAWEVDTLRGHMNNVSCVMFH---AKQDIIVSNSED 456 K + T GH N+ C+ + I+S SED Sbjct: 287 KGKTLKQYT--GHENSKYCIFANFSVTGGKWIISGSED 322 Score = 57.8 bits (138), Expect = 1e-08 Identities = 42/152 (27%), Positives = 66/152 (43%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 +IWN C LTGH V ++ VVSAS D+T+++++I Sbjct: 112 KIWNMDHMICERTLTGHKLGVNDIAWSSDSRCVVSASDDKTLKIFEI------------- 158 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTK 360 V + + L+GH+ V +F+P L+VSG+ D V++W + Sbjct: 159 --------------VTSRMTKTLKGHNNYVFCCNFNPQSSLVVSGSFDESVRIWDVKTGM 204 Query: 361 AWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 + TL H + VS V F+ +I S S D Sbjct: 205 C--IKTLPAHSDPVSAVSFNRDGSLIASGSYD 234 Score = 48.5 bits (114), Expect = 9e-06 Identities = 42/169 (24%), Positives = 72/169 (42%), Gaps = 19/169 (11%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI--GALRKKTVSPA 174 RIW+ ++ C+ L H+ V SF+ L+ S S D VR+WD G K V Sbjct: 196 RIWDVKTGMCIKTLPAHSDPVSAVSFNRDGSLIASGSYDGLVRIWDTANGQCIKTLVDDE 255 Query: 175 DDIMRLTQMNTD----LFGGVDAVVK------------YVLEGHDRGVNWASFHPT-LPL 303 + + + + + L +D+ +K Y + + +A+F T Sbjct: 256 NPPVAFVKFSPNGKYILASNLDSTLKLWDFSKGKTLKQYTGHENSKYCIFANFSVTGGKW 315 Query: 304 IVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNS 450 I+SG++D ++ +W + + V L GH V H Q+II S + Sbjct: 316 IISGSEDCKIYIWNLQTREI--VQCLEGHTQPVLASDCHPVQNIIASGA 362 Score = 40.4 bits (93), Expect = 0.002 Identities = 23/81 (28%), Positives = 40/81 (49%) Frame = +1 Query: 217 GGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVDTLRGHMN 396 G + + LEGH + ++ A F P + + + D+ VK+W M+ TL GH Sbjct: 73 GSANYKLMCTLEGHTKSISSAKFSPCGKYLGTSSADKTVKIWNMDHMICER--TLTGHKL 130 Query: 397 NVSCVMFHAKQDIIVSNSEDK 459 V+ + + + +VS S+DK Sbjct: 131 GVNDIAWSSDSRCVVSASDDK 151 Score = 39.7 bits (91), Expect = 0.004 Identities = 32/136 (23%), Positives = 56/136 (41%), Gaps = 21/136 (15%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTG-HNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRK-KTVSPA 174 RIW+ + C+ L N V F P +++++LD T+++WD + K + Sbjct: 238 RIWDTANGQCIKTLVDDENPPVAFVKFSPNGKYILASNLDSTLKLWDFSKGKTLKQYTGH 297 Query: 175 DDIMRLTQMNTDLFGGVDAV-----------------VKYVLEGHDRGVNWASFHPTLPL 303 ++ N + GG + + LEGH + V + HP + Sbjct: 298 ENSKYCIFANFSVTGGKWIISGSEDCKIYIWNLQTREIVQCLEGHTQPVLASDCHPVQNI 357 Query: 304 IVSGA--DDRQVKLWR 345 I SGA D ++ +WR Sbjct: 358 IASGALEPDNKIHIWR 373 Score = 38.5 bits (88), Expect = 0.009 Identities = 16/46 (34%), Positives = 26/46 (56%), Gaps = 2/46 (4%) Frame = +1 Query: 4 IWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASL--DQTVRVW 135 IWN Q+R V L GH V+ + HP ++++ S +L D + +W Sbjct: 327 IWNLQTREIVQCLEGHTQPVLASDCHPVQNIIASGALEPDNKIHIW 372
>KTNB1_CHICK (Q5ZIU8) Katanin p80 WD40-containing subunit B1 (Katanin p80| subunit B1) (p80 katanin) Length = 657 Score = 62.8 bits (151), Expect = 5e-10 Identities = 41/155 (26%), Positives = 67/155 (43%), Gaps = 15/155 (9%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI---GALRK-KTVS 168 R+W+ ++ + L GH + FHP V S SLD +++WD+ G + K K+ + Sbjct: 87 RVWDLEAAKILRTLLGHKANICSLDFHPYGSFVASGSLDTDIKLWDVRRKGCIFKYKSHT 146 Query: 169 PADDIMRLTQMNTDLFGGVD-----------AVVKYVLEGHDRGVNWASFHPTLPLIVSG 315 A +R + L D V + GH VN FHP+ L+ SG Sbjct: 147 QAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKVMFEFTGHSGPVNVVEFHPSEYLLASG 206 Query: 316 ADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFH 420 + DR ++ W + K V + V C++F+ Sbjct: 207 SSDRTIRFWDLE--KFHVVSCIEEEATPVRCILFN 239 Score = 55.1 bits (131), Expect = 1e-07 Identities = 42/155 (27%), Positives = 66/155 (42%), Gaps = 15/155 (9%) Frame = +1 Query: 40 LTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALR--KKTVSPADDIMRLTQMNTDL 213 LTGH + KE+L+V+ S ++RVWD+ A + + + +I L Sbjct: 58 LTGHTTPIESLQISAKEELIVAGSQSGSIRVWDLEAAKILRTLLGHKANICSLDFHPYGS 117 Query: 214 F---GGVDAVVK----------YVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMND 354 F G +D +K + + H + V F P + S ADD VKLW + Sbjct: 118 FVASGSLDTDIKLWDVRRKGCIFKYKSHTQAVRCLRFSPDGKWLASAADDHTVKLWDLTA 177 Query: 355 TKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSEDK 459 K + GH V+ V FH + ++ S S D+ Sbjct: 178 GKV--MFEFTGHSGPVNVVEFHPSEYLLASGSSDR 210 Score = 36.2 bits (82), Expect = 0.047 Identities = 21/78 (26%), Positives = 35/78 (44%) Frame = +1 Query: 223 VDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNV 402 V A +++ L GH + LIV+G+ +++W + K + TL GH N+ Sbjct: 50 VKAQLRHELTGHTTPIESLQISAKEELIVAGSQSGSIRVWDLEAAKI--LRTLLGHKANI 107 Query: 403 SCVMFHAKQDIIVSNSED 456 + FH + S S D Sbjct: 108 CSLDFHPYGSFVASGSLD 125 Score = 33.1 bits (74), Expect = 0.40 Identities = 17/51 (33%), Positives = 27/51 (52%) Frame = +1 Query: 301 LIVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSE 453 L+ +G DD QV +W KA L GH + + AK+++IV+ S+ Sbjct: 35 LLATGGDDCQVNVW---SVKAQLRHELTGHTTPIESLQISAKEELIVAGSQ 82
>YCW2_YEAST (P25382) Hypothetical WD-repeat protein YCR072C| Length = 515 Score = 62.0 bits (149), Expect = 8e-10 Identities = 43/161 (26%), Positives = 75/161 (46%), Gaps = 8/161 (4%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 RIW+ ++T + L GH ++V+C S+ P +++ + S+D T+R+WD K+ D Sbjct: 169 RIWDCDTQTPMHTLKGHYNWVLCVSWSPDGEVIATGSMDNTIRLWD-----PKSGQCLGD 223 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHP-------TLPLIVSGADDRQVKL 339 +R GH + + S+ P + P + S + D +K+ Sbjct: 224 ALR---------------------GHSKWITSLSWEPIHLVKPGSKPRLASSSKDGTIKI 262 Query: 340 WRMNDTKAWEVD-TLRGHMNNVSCVMFHAKQDIIVSNSEDK 459 W DT + T+ GH N+VSCV + Q ++ S S D+ Sbjct: 263 W---DTVSRVCQYTMSGHTNSVSCVKW-GGQGLLYSGSHDR 299 Score = 44.3 bits (103), Expect = 2e-04 Identities = 39/153 (25%), Positives = 61/153 (39%), Gaps = 1/153 (0%) Frame = +1 Query: 4 IWN-WQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 +WN +S +A +TGH V +F P +VSAS D ++++WD Sbjct: 385 LWNPLKSTKPIARMTGHQKLVNHVAFSPDGRYIVSASFDNSIKLWD-------------- 430 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTK 360 G D GH V ++ L+VS + D +K+W + T+ Sbjct: 431 -------------GRDGKFISTFRGHVASVYQVAWSSDCRLLVSCSKDTTLKVWDVR-TR 476 Query: 361 AWEVDTLRGHMNNVSCVMFHAKQDIIVSNSEDK 459 VD L GH + V V + + S +DK Sbjct: 477 KLSVD-LPGHKDEVYTVDWSVDGKRVCSGGKDK 508 Score = 42.7 bits (99), Expect = 5e-04 Identities = 48/171 (28%), Positives = 75/171 (43%), Gaps = 17/171 (9%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI---GALRKKTVSP 171 +IW+ SR C ++GH + V C + + L+ S S D+TVRVWDI G S Sbjct: 261 KIWDTVSRVCQYTMSGHTNSVSCVKWGG-QGLLYSGSHDRTVRVWDINSQGRCINILKSH 319 Query: 172 ADDIMRLTQMNTDL---FGGVD----------AVVKYVLEGHDRGVNWASFHPTLPLIVS 312 A + L+ ++TD G D K LE +++ + ++V+ Sbjct: 320 AHWVNHLS-LSTDYALRIGAFDHTGKKPSTPEEAQKKALENYEKICK--KNGNSEEMMVT 376 Query: 313 GADDRQVKLWR-MNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSEDKA 462 +DD + LW + TK + + GH V+ V F IVS S D + Sbjct: 377 ASDDYTMFLWNPLKSTK--PIARMTGHQKLVNHVAFSPDGRYIVSASFDNS 425 Score = 40.0 bits (92), Expect = 0.003 Identities = 32/122 (26%), Positives = 52/122 (42%), Gaps = 3/122 (2%) Frame = +1 Query: 34 AVLTGHNHYVMCASFHPK-EDLVVSASLDQTVRVWDIGALRKKTVSPADDIMRLTQMNTD 210 + + GH ++C++F P +V+ + D T R+WD T M+T Sbjct: 137 SAIAGHGSTILCSAFAPHTSSRMVTGAGDNTARIWDCDTQ--------------TPMHT- 181 Query: 211 LFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEV--DTLR 384 L+GH V S+ P +I +G+ D ++LW D K+ + D LR Sbjct: 182 ------------LKGHYNWVLCVSWSPDGEVIATGSMDNTIRLW---DPKSGQCLGDALR 226 Query: 385 GH 390 GH Sbjct: 227 GH 228 Score = 36.6 bits (83), Expect = 0.036 Identities = 23/71 (32%), Positives = 38/71 (53%), Gaps = 1/71 (1%) Frame = +1 Query: 247 LEGHDRGVNWASFHP-TLPLIVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHA 423 + GH + ++F P T +V+GA D ++W DT+ + TL+GH N V CV + Sbjct: 139 IAGHGSTILCSAFAPHTSSRMVTGAGDNTARIWDC-DTQT-PMHTLKGHYNWVLCVSWSP 196 Query: 424 KQDIIVSNSED 456 ++I + S D Sbjct: 197 DGEVIATGSMD 207 Score = 33.5 bits (75), Expect = 0.30 Identities = 27/114 (23%), Positives = 47/114 (41%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 ++W+ + ++ GH V ++ L+VS S D T++VWD+ Sbjct: 427 KLWDGRDGKFISTFRGHVASVYQVAWSSDCRLLVSCSKDTTLKVWDV------------- 473 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLW 342 R +++ DL G D V Y ++ G + SG D+ V+LW Sbjct: 474 --RTRKLSVDLPGHKDEV--YTVDWSVDGKR----------VCSGGKDKMVRLW 513
>LIS1_RAT (P63004) Platelet-activating factor acetylhydrolase IB alpha| subunit (PAF acetylhydrolase 45 kDa subunit) (PAF-AH 45 kDa subunit) (PAF-AH alpha) (PAFAH alpha) (Lissencephaly-1 protein) (LIS-1) Length = 409 Score = 61.6 bits (148), Expect = 1e-09 Identities = 49/188 (26%), Positives = 83/188 (44%), Gaps = 35/188 (18%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI--GALRK------ 156 ++W++Q C+ + GH+H V + P D +VSAS D+T+++W++ G K Sbjct: 174 KLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHR 233 Query: 157 ---KTVSPADDIMRLTQMNTDLFGGVDAVV----KYVLEGHDRGVNWASFHPTL------ 297 + V P D + + D V V K L H+ V S+ P Sbjct: 234 EWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSIS 293 Query: 298 --------------PLIVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDI 435 P ++SG+ D+ +K+W ++ + TL GH N V V+FH+ Sbjct: 294 EATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMC--LMTLVGHDNWVRGVLFHSGGKF 351 Query: 436 IVSNSEDK 459 I+S ++DK Sbjct: 352 ILSCADDK 359 Score = 57.8 bits (138), Expect = 1e-08 Identities = 49/188 (26%), Positives = 71/188 (37%), Gaps = 35/188 (18%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTV----- 165 ++W Q+ CV TGH +V + L+ S S DQTVRVW + K Sbjct: 216 KMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHE 275 Query: 166 -----------SPADDIMRLTQMNTD---------LFGGVDAVVKY----------VLEG 255 S I T T L G D +K L G Sbjct: 276 HVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVG 335 Query: 256 HDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDI 435 HD V FH I+S ADD+ +++W + + + TL H + V+ + FH Sbjct: 336 HDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRC--MKTLNAHEHFVTSLDFHKTAPY 393 Query: 436 IVSNSEDK 459 +V+ S D+ Sbjct: 394 VVTGSVDQ 401 Score = 55.5 bits (132), Expect = 7e-08 Identities = 46/141 (32%), Positives = 61/141 (43%), Gaps = 1/141 (0%) Frame = +1 Query: 40 LTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDIMRLTQMNTDLFG 219 L+GH V FHP ++VSAS D T++VWD D R Sbjct: 103 LSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDY---------ETGDFER---------- 143 Query: 220 GVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWE-VDTLRGHMN 396 L+GH V SF + L+ S + D +KLW D + +E + T+ GH + Sbjct: 144 --------TLKGHTDSVQDISFDHSGKLLASCSADMTIKLW---DFQGFECIRTMHGHDH 192 Query: 397 NVSCVMFHAKQDIIVSNSEDK 459 NVS V D IVS S DK Sbjct: 193 NVSSVAIMPNGDHIVSASRDK 213 Score = 50.8 bits (120), Expect = 2e-06 Identities = 18/46 (39%), Positives = 30/46 (65%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWD 138 R+W+++++ C+ L H H+V FH VV+ S+DQTV+VW+ Sbjct: 362 RVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWE 407 Score = 50.8 bits (120), Expect = 2e-06 Identities = 31/114 (27%), Positives = 50/114 (43%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 ++W+ + C+ L GH+++V FH ++S + D+T+RVWD R Sbjct: 320 KMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRC-------- 371 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLW 342 M T L H+ V FH T P +V+G+ D+ VK+W Sbjct: 372 ------MKT-------------LNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVW 406 Score = 44.7 bits (104), Expect = 1e-04 Identities = 25/73 (34%), Positives = 39/73 (53%) Frame = +1 Query: 238 KYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMF 417 KY L GH V FHP ++VS ++D +K+W +T +E TL+GH ++V + F Sbjct: 100 KYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDY-ETGDFE-RTLKGHTDSVQDISF 157 Query: 418 HAKQDIIVSNSED 456 ++ S S D Sbjct: 158 DHSGKLLASCSAD 170
>LIS1_PANTR (Q5IS43) Platelet-activating factor acetylhydrolase IB alpha| subunit (PAF acetylhydrolase 45 kDa subunit) (PAF-AH 45 kDa subunit) (PAF-AH alpha) (PAFAH alpha) (Lissencephaly-1 protein) (LIS-1) Length = 409 Score = 61.6 bits (148), Expect = 1e-09 Identities = 49/188 (26%), Positives = 83/188 (44%), Gaps = 35/188 (18%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI--GALRK------ 156 ++W++Q C+ + GH+H V + P D +VSAS D+T+++W++ G K Sbjct: 174 KLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHR 233 Query: 157 ---KTVSPADDIMRLTQMNTDLFGGVDAVV----KYVLEGHDRGVNWASFHPTL------ 297 + V P D + + D V V K L H+ V S+ P Sbjct: 234 EWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSIS 293 Query: 298 --------------PLIVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDI 435 P ++SG+ D+ +K+W ++ + TL GH N V V+FH+ Sbjct: 294 EATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMC--LMTLVGHDNWVRGVLFHSGGKF 351 Query: 436 IVSNSEDK 459 I+S ++DK Sbjct: 352 ILSCADDK 359 Score = 55.5 bits (132), Expect = 7e-08 Identities = 48/188 (25%), Positives = 70/188 (37%), Gaps = 35/188 (18%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTV----- 165 ++W Q+ CV TGH +V + L+ S S DQTVRVW + K Sbjct: 216 KMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHE 275 Query: 166 -----------SPADDIMRLTQMNTD---------LFGGVDAVVKY----------VLEG 255 S I T T L G D +K L G Sbjct: 276 HVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVG 335 Query: 256 HDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDI 435 HD V FH I+S ADD+ +++W + + + TL H + V+ + FH Sbjct: 336 HDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRC--MKTLNAHEHFVTSLDFHKTAPY 393 Query: 436 IVSNSEDK 459 +V+ D+ Sbjct: 394 VVTGFVDQ 401 Score = 55.5 bits (132), Expect = 7e-08 Identities = 46/141 (32%), Positives = 61/141 (43%), Gaps = 1/141 (0%) Frame = +1 Query: 40 LTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDIMRLTQMNTDLFG 219 L+GH V FHP ++VSAS D T++VWD D R Sbjct: 103 LSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDY---------ETGDFER---------- 143 Query: 220 GVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWE-VDTLRGHMN 396 L+GH V SF + L+ S + D +KLW D + +E + T+ GH + Sbjct: 144 --------TLKGHTDSVQDISFDHSGKLLASCSADMTIKLW---DFQGFECIRTMHGHDH 192 Query: 397 NVSCVMFHAKQDIIVSNSEDK 459 NVS V D IVS S DK Sbjct: 193 NVSSVAIMPNGDHIVSASRDK 213 Score = 49.7 bits (117), Expect = 4e-06 Identities = 31/114 (27%), Positives = 49/114 (42%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 ++W+ + C+ L GH+++V FH ++S + D+T+RVWD R Sbjct: 320 KMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRC-------- 371 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLW 342 M T L H+ V FH T P +V+G D+ VK+W Sbjct: 372 ------MKT-------------LNAHEHFVTSLDFHKTAPYVVTGFVDQTVKVW 406 Score = 48.5 bits (114), Expect = 9e-06 Identities = 17/46 (36%), Positives = 29/46 (63%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWD 138 R+W+++++ C+ L H H+V FH VV+ +DQTV+VW+ Sbjct: 362 RVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGFVDQTVKVWE 407 Score = 44.7 bits (104), Expect = 1e-04 Identities = 25/73 (34%), Positives = 39/73 (53%) Frame = +1 Query: 238 KYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMF 417 KY L GH V FHP ++VS ++D +K+W +T +E TL+GH ++V + F Sbjct: 100 KYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDY-ETGDFE-RTLKGHTDSVQDISF 157 Query: 418 HAKQDIIVSNSED 456 ++ S S D Sbjct: 158 DHSGKLLASCSAD 170
>LIS1_MOUSE (P63005) Platelet-activating factor acetylhydrolase IB alpha| subunit (PAF acetylhydrolase 45 kDa subunit) (PAF-AH 45 kDa subunit) (PAF-AH alpha) (PAFAH alpha) (Lissencephaly-1 protein) (LIS-1) Length = 409 Score = 61.6 bits (148), Expect = 1e-09 Identities = 49/188 (26%), Positives = 83/188 (44%), Gaps = 35/188 (18%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI--GALRK------ 156 ++W++Q C+ + GH+H V + P D +VSAS D+T+++W++ G K Sbjct: 174 KLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHR 233 Query: 157 ---KTVSPADDIMRLTQMNTDLFGGVDAVV----KYVLEGHDRGVNWASFHPTL------ 297 + V P D + + D V V K L H+ V S+ P Sbjct: 234 EWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSIS 293 Query: 298 --------------PLIVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDI 435 P ++SG+ D+ +K+W ++ + TL GH N V V+FH+ Sbjct: 294 EATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMC--LMTLVGHDNWVRGVLFHSGGKF 351 Query: 436 IVSNSEDK 459 I+S ++DK Sbjct: 352 ILSCADDK 359 Score = 57.8 bits (138), Expect = 1e-08 Identities = 49/188 (26%), Positives = 71/188 (37%), Gaps = 35/188 (18%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTV----- 165 ++W Q+ CV TGH +V + L+ S S DQTVRVW + K Sbjct: 216 KMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHE 275 Query: 166 -----------SPADDIMRLTQMNTD---------LFGGVDAVVKY----------VLEG 255 S I T T L G D +K L G Sbjct: 276 HVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVG 335 Query: 256 HDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDI 435 HD V FH I+S ADD+ +++W + + + TL H + V+ + FH Sbjct: 336 HDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRC--MKTLNAHEHFVTSLDFHKTAPY 393 Query: 436 IVSNSEDK 459 +V+ S D+ Sbjct: 394 VVTGSVDQ 401 Score = 55.5 bits (132), Expect = 7e-08 Identities = 46/141 (32%), Positives = 61/141 (43%), Gaps = 1/141 (0%) Frame = +1 Query: 40 LTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDIMRLTQMNTDLFG 219 L+GH V FHP ++VSAS D T++VWD D R Sbjct: 103 LSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDY---------ETGDFER---------- 143 Query: 220 GVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWE-VDTLRGHMN 396 L+GH V SF + L+ S + D +KLW D + +E + T+ GH + Sbjct: 144 --------TLKGHTDSVQDISFDHSGKLLASCSADMTIKLW---DFQGFECIRTMHGHDH 192 Query: 397 NVSCVMFHAKQDIIVSNSEDK 459 NVS V D IVS S DK Sbjct: 193 NVSSVAIMPNGDHIVSASRDK 213 Score = 50.8 bits (120), Expect = 2e-06 Identities = 18/46 (39%), Positives = 30/46 (65%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWD 138 R+W+++++ C+ L H H+V FH VV+ S+DQTV+VW+ Sbjct: 362 RVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWE 407 Score = 50.8 bits (120), Expect = 2e-06 Identities = 31/114 (27%), Positives = 50/114 (43%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 ++W+ + C+ L GH+++V FH ++S + D+T+RVWD R Sbjct: 320 KMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRC-------- 371 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLW 342 M T L H+ V FH T P +V+G+ D+ VK+W Sbjct: 372 ------MKT-------------LNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVW 406 Score = 44.7 bits (104), Expect = 1e-04 Identities = 25/73 (34%), Positives = 39/73 (53%) Frame = +1 Query: 238 KYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMF 417 KY L GH V FHP ++VS ++D +K+W +T +E TL+GH ++V + F Sbjct: 100 KYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDY-ETGDFE-RTLKGHTDSVQDISF 157 Query: 418 HAKQDIIVSNSED 456 ++ S S D Sbjct: 158 DHSGKLLASCSAD 170
>LIS1_HUMAN (P43034) Platelet-activating factor acetylhydrolase IB alpha| subunit (PAF acetylhydrolase 45 kDa subunit) (PAF-AH 45 kDa subunit) (PAF-AH alpha) (PAFAH alpha) (Lissencephaly-1 protein) (LIS-1) Length = 409 Score = 61.6 bits (148), Expect = 1e-09 Identities = 49/188 (26%), Positives = 83/188 (44%), Gaps = 35/188 (18%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI--GALRK------ 156 ++W++Q C+ + GH+H V + P D +VSAS D+T+++W++ G K Sbjct: 174 KLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHR 233 Query: 157 ---KTVSPADDIMRLTQMNTDLFGGVDAVV----KYVLEGHDRGVNWASFHPTL------ 297 + V P D + + D V V K L H+ V S+ P Sbjct: 234 EWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSIS 293 Query: 298 --------------PLIVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDI 435 P ++SG+ D+ +K+W ++ + TL GH N V V+FH+ Sbjct: 294 EATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMC--LMTLVGHDNWVRGVLFHSGGKF 351 Query: 436 IVSNSEDK 459 I+S ++DK Sbjct: 352 ILSCADDK 359 Score = 57.8 bits (138), Expect = 1e-08 Identities = 49/188 (26%), Positives = 71/188 (37%), Gaps = 35/188 (18%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTV----- 165 ++W Q+ CV TGH +V + L+ S S DQTVRVW + K Sbjct: 216 KMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHE 275 Query: 166 -----------SPADDIMRLTQMNTD---------LFGGVDAVVKY----------VLEG 255 S I T T L G D +K L G Sbjct: 276 HVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVG 335 Query: 256 HDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDI 435 HD V FH I+S ADD+ +++W + + + TL H + V+ + FH Sbjct: 336 HDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRC--MKTLNAHEHFVTSLDFHKTAPY 393 Query: 436 IVSNSEDK 459 +V+ S D+ Sbjct: 394 VVTGSVDQ 401 Score = 55.5 bits (132), Expect = 7e-08 Identities = 46/141 (32%), Positives = 61/141 (43%), Gaps = 1/141 (0%) Frame = +1 Query: 40 LTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDIMRLTQMNTDLFG 219 L+GH V FHP ++VSAS D T++VWD D R Sbjct: 103 LSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDY---------ETGDFER---------- 143 Query: 220 GVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWE-VDTLRGHMN 396 L+GH V SF + L+ S + D +KLW D + +E + T+ GH + Sbjct: 144 --------TLKGHTDSVQDISFDHSGKLLASCSADMTIKLW---DFQGFECIRTMHGHDH 192 Query: 397 NVSCVMFHAKQDIIVSNSEDK 459 NVS V D IVS S DK Sbjct: 193 NVSSVAIMPNGDHIVSASRDK 213 Score = 50.8 bits (120), Expect = 2e-06 Identities = 18/46 (39%), Positives = 30/46 (65%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWD 138 R+W+++++ C+ L H H+V FH VV+ S+DQTV+VW+ Sbjct: 362 RVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWE 407 Score = 50.8 bits (120), Expect = 2e-06 Identities = 31/114 (27%), Positives = 50/114 (43%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 ++W+ + C+ L GH+++V FH ++S + D+T+RVWD R Sbjct: 320 KMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRC-------- 371 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLW 342 M T L H+ V FH T P +V+G+ D+ VK+W Sbjct: 372 ------MKT-------------LNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVW 406 Score = 44.7 bits (104), Expect = 1e-04 Identities = 25/73 (34%), Positives = 39/73 (53%) Frame = +1 Query: 238 KYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMF 417 KY L GH V FHP ++VS ++D +K+W +T +E TL+GH ++V + F Sbjct: 100 KYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDY-ETGDFE-RTLKGHTDSVQDISF 157 Query: 418 HAKQDIIVSNSED 456 ++ S S D Sbjct: 158 DHSGKLLASCSAD 170
>LIS1_BOVIN (P43033) Platelet-activating factor acetylhydrolase IB alpha| subunit (PAF acetylhydrolase 45 kDa subunit) (PAF-AH 45 kDa subunit) (PAF-AH alpha) (PAFAH alpha) (Lissencephaly-1 protein) (LIS-1) Length = 409 Score = 61.6 bits (148), Expect = 1e-09 Identities = 49/188 (26%), Positives = 83/188 (44%), Gaps = 35/188 (18%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI--GALRK------ 156 ++W++Q C+ + GH+H V + P D +VSAS D+T+++W++ G K Sbjct: 174 KLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHR 233 Query: 157 ---KTVSPADDIMRLTQMNTDLFGGVDAVV----KYVLEGHDRGVNWASFHPTL------ 297 + V P D + + D V V K L H+ V S+ P Sbjct: 234 EWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSIS 293 Query: 298 --------------PLIVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDI 435 P ++SG+ D+ +K+W ++ + TL GH N V V+FH+ Sbjct: 294 EATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMC--LMTLVGHDNWVRGVLFHSGGKF 351 Query: 436 IVSNSEDK 459 I+S ++DK Sbjct: 352 ILSCADDK 359 Score = 57.8 bits (138), Expect = 1e-08 Identities = 49/188 (26%), Positives = 71/188 (37%), Gaps = 35/188 (18%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTV----- 165 ++W Q+ CV TGH +V + L+ S S DQTVRVW + K Sbjct: 216 KMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHE 275 Query: 166 -----------SPADDIMRLTQMNTD---------LFGGVDAVVKY----------VLEG 255 S I T T L G D +K L G Sbjct: 276 HVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVG 335 Query: 256 HDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDI 435 HD V FH I+S ADD+ +++W + + + TL H + V+ + FH Sbjct: 336 HDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRC--MKTLNAHEHFVTSLDFHKTAPY 393 Query: 436 IVSNSEDK 459 +V+ S D+ Sbjct: 394 VVTGSVDQ 401 Score = 55.5 bits (132), Expect = 7e-08 Identities = 46/141 (32%), Positives = 61/141 (43%), Gaps = 1/141 (0%) Frame = +1 Query: 40 LTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDIMRLTQMNTDLFG 219 L+GH V FHP ++VSAS D T++VWD D R Sbjct: 103 LSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDY---------ETGDFER---------- 143 Query: 220 GVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWE-VDTLRGHMN 396 L+GH V SF + L+ S + D +KLW D + +E + T+ GH + Sbjct: 144 --------TLKGHTDSVEDISFDHSGKLLASCSADMTIKLW---DFQGFECIRTMHGHDH 192 Query: 397 NVSCVMFHAKQDIIVSNSEDK 459 NVS V D IVS S DK Sbjct: 193 NVSSVAIMPNGDHIVSASRDK 213 Score = 50.8 bits (120), Expect = 2e-06 Identities = 18/46 (39%), Positives = 30/46 (65%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWD 138 R+W+++++ C+ L H H+V FH VV+ S+DQTV+VW+ Sbjct: 362 RVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWE 407 Score = 50.8 bits (120), Expect = 2e-06 Identities = 31/114 (27%), Positives = 50/114 (43%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 ++W+ + C+ L GH+++V FH ++S + D+T+RVWD R Sbjct: 320 KMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRC-------- 371 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLW 342 M T L H+ V FH T P +V+G+ D+ VK+W Sbjct: 372 ------MKT-------------LNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVW 406 Score = 44.7 bits (104), Expect = 1e-04 Identities = 25/73 (34%), Positives = 39/73 (53%) Frame = +1 Query: 238 KYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMF 417 KY L GH V FHP ++VS ++D +K+W +T +E TL+GH ++V + F Sbjct: 100 KYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDY-ETGDFE-RTLKGHTDSVEDISF 157 Query: 418 HAKQDIIVSNSED 456 ++ S S D Sbjct: 158 DHSGKLLASCSAD 170
>TUP1_CANAL (P56093) Transcriptional repressor TUP1| Length = 514 Score = 61.6 bits (148), Expect = 1e-09 Identities = 51/189 (26%), Positives = 83/189 (43%), Gaps = 29/189 (15%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 RIW+ ++ + +L GH + F P D +VS S D++VR+WD+ + +D Sbjct: 282 RIWDLSTKRIIKILRGHEQDIYSLDFFPDGDRLVSGSGDRSVRIWDLRTSQCSLTLSIED 341 Query: 181 IMRLTQMNTD----LFGGVDAVVK-------YVLE----------GHDRGVNWASFHPTL 297 + ++ D G +D V+ +++E GH+ V +F Sbjct: 342 GVTTVAVSPDGKLIAAGSLDRTVRVWDSTTGFLVERLDSGNENGNGHEDSVYSVAFSNNG 401 Query: 298 PLIVSGADDRQVKLWRM---NDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSEDKAF- 465 I SG+ DR VKLW + +D K+ T GH + V V + I+S S+D+ Sbjct: 402 EQIASGSLDRTVKLWHLEGKSDKKSTCEVTYIGHKDFVLSVCCTPDNEYILSGSKDRGVI 461 Query: 466 ----ASGMP 480 ASG P Sbjct: 462 FWDQASGNP 470 Score = 39.7 bits (91), Expect = 0.004 Identities = 22/101 (21%), Positives = 43/101 (42%) Frame = +1 Query: 58 YVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDIMRLTQMNTDLFGGVDAVV 237 Y+ F P L+ + + D+ +R+WD+ R ++ Sbjct: 259 YIRSVCFSPDGKLLATGAEDKLIRIWDLSTKR--------------------------II 292 Query: 238 KYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTK 360 K +L GH++ + F P +VSG+ DR V++W + ++ Sbjct: 293 K-ILRGHEQDIYSLDFFPDGDRLVSGSGDRSVRIWDLRTSQ 332
>WD51B_PONPY (Q5RD06) WD-repeat protein 51B| Length = 451 Score = 61.2 bits (147), Expect = 1e-09 Identities = 38/152 (25%), Positives = 65/152 (42%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 ++W+ + + L H H+V CA F P L+VS S D+T+++WD K+ V+ D Sbjct: 127 KVWSMYRQRFLYSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIWD--TTNKQCVNNFSD 184 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTK 360 + N+ F+P+ I S D+ VK+W + K Sbjct: 185 SVGF-------------------------ANFVDFNPSGTCIASAGSDQTVKVWDVRVNK 219 Query: 361 AWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 + + H V+C+ FH + +V+ S D Sbjct: 220 L--LQHYQVHSGGVNCISFHPSDNYLVTASSD 249 Score = 52.0 bits (123), Expect = 8e-07 Identities = 36/132 (27%), Positives = 56/132 (42%), Gaps = 15/132 (11%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI------------- 141 +IW+ ++ CV + + F+P + SA DQTV+VWD+ Sbjct: 169 KIWDTTNKQCVNNFSDSVGFANFVDFNPSGTCIASAGSDQTVKVWDVRVNKLLQHYQVHS 228 Query: 142 GALRKKTVSPADDIMRLTQMNTDL--FGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSG 315 G + + P+D+ + + L ++ + Y L+GH V SF L SG Sbjct: 229 GGVNCISFHPSDNYLVTASSDGTLKILDLLEGRLIYTLQGHTGPVFTVSFSKGGELFASG 288 Query: 316 ADDRQVKLWRMN 351 D QV LWR N Sbjct: 289 GADTQVLLWRTN 300 Score = 44.7 bits (104), Expect = 1e-04 Identities = 38/152 (25%), Positives = 58/152 (38%) Frame = +1 Query: 4 IWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDI 183 +WN++ GH V F P +L+ SAS D+TVR+W I R K Sbjct: 44 LWNFKPHARAYRYVGHKDVVTSVQFSPHGNLLASASRDRTVRLW-IPDKRGKFSE----- 97 Query: 184 MRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKA 363 + H V F + + ++D+ +K+W M + Sbjct: 98 ---------------------FKAHTAPVRSVDFSADGQFLATASEDKSIKVWSMYRQRF 136 Query: 364 WEVDTLRGHMNNVSCVMFHAKQDIIVSNSEDK 459 + +L H + V C F +IVS SEDK Sbjct: 137 --LYSLYRHTHWVRCAKFSPDGRLIVSCSEDK 166 Score = 33.1 bits (74), Expect = 0.40 Identities = 23/74 (31%), Positives = 32/74 (43%) Frame = +1 Query: 241 YVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFH 420 Y GH V F P L+ S + DR V+LW + K + + H V V F Sbjct: 54 YRYVGHKDVVTSVQFSPHGNLLASASRDRTVRLWIPD--KRGKFSEFKAHTAPVRSVDFS 111 Query: 421 AKQDIIVSNSEDKA 462 A + + SEDK+ Sbjct: 112 ADGQFLATASEDKS 125
>LIS1_MACFA (Q8HXX0) Platelet-activating factor acetylhydrolase IB alpha| subunit (PAF acetylhydrolase 45 kDa subunit) (PAF-AH 45 kDa subunit) (PAF-AH alpha) (PAFAH alpha) (Lissencephaly-1 protein) (LIS-1) Length = 409 Score = 60.8 bits (146), Expect = 2e-09 Identities = 49/188 (26%), Positives = 83/188 (44%), Gaps = 35/188 (18%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI--GALRK------ 156 ++W++Q C+ + GH+H V + P D +VSAS D+T+++W++ G K Sbjct: 174 KLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHLVSASRDKTIKMWEVQTGYCVKTFTGHR 233 Query: 157 ---KTVSPADDIMRLTQMNTDLFGGVDAVV----KYVLEGHDRGVNWASFHPTL------ 297 + V P D + + D V V K L H+ V S+ P Sbjct: 234 EWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSIS 293 Query: 298 --------------PLIVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDI 435 P ++SG+ D+ +K+W ++ + TL GH N V V+FH+ Sbjct: 294 EATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMC--LMTLVGHDNWVRGVLFHSGGKF 351 Query: 436 IVSNSEDK 459 I+S ++DK Sbjct: 352 ILSCADDK 359 Score = 57.8 bits (138), Expect = 1e-08 Identities = 49/188 (26%), Positives = 71/188 (37%), Gaps = 35/188 (18%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTV----- 165 ++W Q+ CV TGH +V + L+ S S DQTVRVW + K Sbjct: 216 KMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHE 275 Query: 166 -----------SPADDIMRLTQMNTD---------LFGGVDAVVKY----------VLEG 255 S I T T L G D +K L G Sbjct: 276 HVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVG 335 Query: 256 HDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDI 435 HD V FH I+S ADD+ +++W + + + TL H + V+ + FH Sbjct: 336 HDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRC--MKTLNAHEHFVTSLDFHKTAPY 393 Query: 436 IVSNSEDK 459 +V+ S D+ Sbjct: 394 VVTGSVDQ 401 Score = 54.7 bits (130), Expect = 1e-07 Identities = 45/141 (31%), Positives = 61/141 (43%), Gaps = 1/141 (0%) Frame = +1 Query: 40 LTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDIMRLTQMNTDLFG 219 L+GH V FHP ++VSAS D T++VWD D R Sbjct: 103 LSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDY---------ETGDFER---------- 143 Query: 220 GVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWE-VDTLRGHMN 396 L+GH V SF + L+ S + D +KLW D + +E + T+ GH + Sbjct: 144 --------TLKGHTDSVQDISFDHSGKLLTSCSADMTIKLW---DFQGFECIRTMHGHDH 192 Query: 397 NVSCVMFHAKQDIIVSNSEDK 459 NVS V D +VS S DK Sbjct: 193 NVSSVAIMPNGDHLVSASRDK 213 Score = 50.8 bits (120), Expect = 2e-06 Identities = 18/46 (39%), Positives = 30/46 (65%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWD 138 R+W+++++ C+ L H H+V FH VV+ S+DQTV+VW+ Sbjct: 362 RVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWE 407 Score = 50.8 bits (120), Expect = 2e-06 Identities = 31/114 (27%), Positives = 50/114 (43%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 ++W+ + C+ L GH+++V FH ++S + D+T+RVWD R Sbjct: 320 KMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRC-------- 371 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLW 342 M T L H+ V FH T P +V+G+ D+ VK+W Sbjct: 372 ------MKT-------------LNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVW 406 Score = 44.7 bits (104), Expect = 1e-04 Identities = 25/73 (34%), Positives = 39/73 (53%) Frame = +1 Query: 238 KYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMF 417 KY L GH V FHP ++VS ++D +K+W +T +E TL+GH ++V + F Sbjct: 100 KYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDY-ETGDFE-RTLKGHTDSVQDISF 157 Query: 418 HAKQDIIVSNSED 456 ++ S S D Sbjct: 158 DHSGKLLTSCSAD 170
>PLRG1_MOUSE (Q922V4) Pleiotropic regulator 1| Length = 513 Score = 60.1 bits (144), Expect = 3e-09 Identities = 46/155 (29%), Positives = 74/155 (47%), Gaps = 15/155 (9%) Frame = +1 Query: 37 VLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKT-----VSPADDIMRLTQM 201 V++GH +V C + P V+ S D+T+++WD+ + + K +S ++ T+ Sbjct: 198 VISGHLGWVRCIAVEPGNQWFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRS 257 Query: 202 NTDLFGGVDAVVK-YVLE---------GHDRGVNWASFHPTLPLIVSGADDRQVKLWRMN 351 G D VK + LE GH V HPTL ++V+ + D ++W + Sbjct: 258 PYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTLDVLVTCSRDSTARIWDVR 317 Query: 352 DTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 TKA V TL GH N V+ V A + I++ S D Sbjct: 318 -TKA-SVHTLSGHTNAVATVRCQAAEPQIITGSHD 350 Score = 45.8 bits (107), Expect = 6e-05 Identities = 34/152 (22%), Positives = 61/152 (40%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 RIW+ +++ V L+GH + V E +++ S D T+R+WD+ Sbjct: 312 RIWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDL------------- 358 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTK 360 V + L H + V HP L SG+ D +K W+ D Sbjct: 359 --------------VAGKTRVTLTNHKKSVRAVVLHPLLYTFASGSPD-NIKQWKFPD-- 401 Query: 361 AWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 + L GH ++ + +A ++VS +++ Sbjct: 402 GGFIQNLSGHNAIINTLAVNA-DGVLVSGADN 432 Score = 45.4 bits (106), Expect = 8e-05 Identities = 36/152 (23%), Positives = 55/152 (36%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 + W+ + + GH V HP D++V+ S D T R+WD+ K +V Sbjct: 270 KCWDLEYNKVIRHYHGHLSAVYGLDLHPTLDVLVTCSRDSTARIWDVRT--KASV----- 322 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTK 360 + L GH V P I++G+ D ++LW + K Sbjct: 323 --------------------HTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVAGK 362 Query: 361 AWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 TL H +V V+ H S S D Sbjct: 363 TRV--TLTNHKKSVRAVVLHPLLYTFASGSPD 392
>WD51B_HUMAN (Q8TC44) WD-repeat protein 51B| Length = 478 Score = 60.1 bits (144), Expect = 3e-09 Identities = 37/152 (24%), Positives = 65/152 (42%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 ++W+ + + L H H+V CA F P L+VS S D+T+++WD K+ V+ D Sbjct: 127 KVWSMYRQRFLYSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIWD--TTNKQCVNNFSD 184 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTK 360 + N+ F+P+ I S D+ VK+W + K Sbjct: 185 SVGF-------------------------ANFVDFNPSGTCIASAGSDQTVKVWDVRVNK 219 Query: 361 AWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 + + H V+C+ FH + +++ S D Sbjct: 220 L--LQHYQVHSGGVNCISFHPSGNYLITASSD 249 Score = 49.3 bits (116), Expect = 5e-06 Identities = 35/132 (26%), Positives = 55/132 (41%), Gaps = 15/132 (11%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI------------- 141 +IW+ ++ CV + + F+P + SA DQTV+VWD+ Sbjct: 169 KIWDTTNKQCVNNFSDSVGFANFVDFNPSGTCIASAGSDQTVKVWDVRVNKLLQHYQVHS 228 Query: 142 GALRKKTVSPADD--IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSG 315 G + + P+ + I + + ++ + Y L+GH V SF L SG Sbjct: 229 GGVNCISFHPSGNYLITASSDGTLKILDLLEGRLIYTLQGHTGPVFTVSFSKGGELFASG 288 Query: 316 ADDRQVKLWRMN 351 D QV LWR N Sbjct: 289 GADTQVLLWRTN 300 Score = 44.7 bits (104), Expect = 1e-04 Identities = 38/152 (25%), Positives = 58/152 (38%) Frame = +1 Query: 4 IWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDI 183 +WN++ GH V F P +L+ SAS D+TVR+W I R K Sbjct: 44 LWNFKPHARAYRYVGHKDVVTSVQFSPHGNLLASASRDRTVRLW-IPDKRGKFSE----- 97 Query: 184 MRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKA 363 + H V F + + ++D+ +K+W M + Sbjct: 98 ---------------------FKAHTAPVRSVDFSADGQFLATASEDKSIKVWSMYRQRF 136 Query: 364 WEVDTLRGHMNNVSCVMFHAKQDIIVSNSEDK 459 + +L H + V C F +IVS SEDK Sbjct: 137 --LYSLYRHTHWVRCAKFSPDGRLIVSCSEDK 166 Score = 33.1 bits (74), Expect = 0.40 Identities = 23/74 (31%), Positives = 32/74 (43%) Frame = +1 Query: 241 YVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFH 420 Y GH V F P L+ S + DR V+LW + K + + H V V F Sbjct: 54 YRYVGHKDVVTSVQFSPHGNLLASASRDRTVRLWIPD--KRGKFSEFKAHTAPVRSVDFS 111 Query: 421 AKQDIIVSNSEDKA 462 A + + SEDK+ Sbjct: 112 ADGQFLATASEDKS 125
>PRL1_ARATH (Q42384) PP1/PP2A phosphatases pleiotropic regulator PRL1| Length = 486 Score = 59.7 bits (143), Expect = 4e-09 Identities = 40/161 (24%), Positives = 63/161 (39%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 + W+ + + GH V C + HP D++++ D RVWDI Sbjct: 243 KCWDLEQNKVIRSYHGHLSGVYCLALHPTLDVLLTGGRDSVCRVWDI------------- 289 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTK 360 T+M + L GHD V PT P +V+G+ D +K W + K Sbjct: 290 ---RTKMQI-----------FALSGHDNTVCSVFTRPTDPQVVTGSHDTTIKFWDLRYGK 335 Query: 361 AWEVDTLRGHMNNVSCVMFHAKQDIIVSNSEDKAFASGMPQ 483 + TL H +V + H K++ S S D +P+ Sbjct: 336 T--MSTLTHHKKSVRAMTLHPKENAFASASADNTKKFSLPK 374 Score = 57.0 bits (136), Expect = 3e-08 Identities = 43/155 (27%), Positives = 70/155 (45%), Gaps = 15/155 (9%) Frame = +1 Query: 37 VLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI--GALRKKTVSPADDIMRLTQMNTD 210 V+ GH +V +F P + + S D+T+++WD+ G L+ + + L N Sbjct: 171 VIQGHLGWVRSVAFDPSNEWFCTGSADRTIKIWDVATGVLKLTLTGHIEQVRGLAVSNRH 230 Query: 211 LF---GGVDAVVK-YVLE---------GHDRGVNWASFHPTLPLIVSGADDRQVKLWRMN 351 + G D VK + LE GH GV + HPTL ++++G D ++W + Sbjct: 231 TYMFSAGDDKQVKCWDLEQNKVIRSYHGHLSGVYCLALHPTLDVLLTGGRDSVCRVWDIR 290 Query: 352 DTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 TK ++ L GH N V V +V+ S D Sbjct: 291 -TK-MQIFALSGHDNTVCSVFTRPTDPQVVTGSHD 323
>Y2124_ANASP (Q8YV57) Hypothetical WD-repeat protein all2124| Length = 1683 Score = 59.7 bits (143), Expect = 4e-09 Identities = 43/167 (25%), Positives = 70/167 (41%), Gaps = 15/167 (8%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWD-IGALRKKTVSPAD 177 ++WN L GH V SF P ++ SAS D+T+R+WD K++ + Sbjct: 1471 KLWNVSDGKFKKTLKGHTDEVFWVSFSPDGKIIASASADKTIRLWDSFSGNLIKSLPAHN 1530 Query: 178 DIMRLTQMNTD--------------LFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSG 315 D++ N D L+ D + + GH V +SF P I S Sbjct: 1531 DLVYSVNFNPDGSMLASTSADKTVKLWRSHDGHLLHTFSGHSNVVYSSSFSPDGRYIASA 1590 Query: 316 ADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 ++D+ VK+W+++ + TL H V +F ++S S D Sbjct: 1591 SEDKTVKIWQID---GHLLTTLPQHQAGVMSAIFSPDGKTLISGSLD 1634 Score = 59.7 bits (143), Expect = 4e-09 Identities = 48/171 (28%), Positives = 76/171 (44%), Gaps = 19/171 (11%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 ++WN + TGH+ V +F P +++ SASLD T+R+W ++ +SP + Sbjct: 1306 KLWNRHGIE-LETFTGHSGGVYAVNFLPDSNIIASASLDNTIRLW-----QRPLISPLEV 1359 Query: 181 IMRLTQM-------------------NTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPL 303 + + + N L+ D + L G ++ + SF P L Sbjct: 1360 LAGNSGVYAVSFLHDGSIIATAGADGNIQLWHSQDGSLLKTLPG-NKAIYGISFTPQGDL 1418 Query: 304 IVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 I S D+ VK+WR+ D KA + TL GH N V+ V F + S S D Sbjct: 1419 IASANADKTVKIWRVRDGKA--LKTLIGHDNEVNKVNFSPDGKTLASASRD 1467 Score = 59.7 bits (143), Expect = 4e-09 Identities = 47/168 (27%), Positives = 69/168 (41%), Gaps = 15/168 (8%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI--GALRK------ 156 ++W+ R L GH V SF P + S D+T+++W G L K Sbjct: 1097 KLWSRDGRL-FRTLNGHEDAVYSVSFSPDGQTIASGGSDKTIKLWQTSDGTLLKTITGHE 1155 Query: 157 ---KTVSPADDIMRLTQMNTD----LFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSG 315 V + D L ++D L+ + L GH GV F P I +G Sbjct: 1156 QTVNNVYFSPDGKNLASASSDHSIKLWDTTSGQLLMTLTGHSAGVITVRFSPDGQTIAAG 1215 Query: 316 ADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSEDK 459 ++D+ VKLW D K + TL GH + V+ + F + S S DK Sbjct: 1216 SEDKTVKLWHRQDGKL--LKTLNGHQDWVNSLSFSPDGKTLASASADK 1261 Score = 57.0 bits (136), Expect = 3e-08 Identities = 42/154 (27%), Positives = 64/154 (41%), Gaps = 14/154 (9%) Frame = +1 Query: 40 LTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDIMRLTQMNTD--- 210 L GH V+ S + S SLD+T+++W +T++ +D + + D Sbjct: 1068 LEGHKDGVISISISRDGQTIASGSLDKTIKLWSRDGRLFRTLNGHEDAVYSVSFSPDGQT 1127 Query: 211 -LFGGVDAVVKY----------VLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDT 357 GG D +K + GH++ VN F P + S + D +KLW + T Sbjct: 1128 IASGGSDKTIKLWQTSDGTLLKTITGHEQTVNNVYFSPDGKNLASASSDHSIKLW--DTT 1185 Query: 358 KAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSEDK 459 + TL GH V V F I + SEDK Sbjct: 1186 SGQLLMTLTGHSAGVITVRFSPDGQTIAAGSEDK 1219 Score = 56.6 bits (135), Expect = 3e-08 Identities = 39/153 (25%), Positives = 63/153 (41%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 +IW + + L GH++ V +F P + SAS D TV++W++ Sbjct: 1429 KIWRVRDGKALKTLIGHDNEVNKVNFSPDGKTLASASRDNTVKLWNVS------------ 1476 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTK 360 D K L+GH V W SF P +I S + D+ ++LW + Sbjct: 1477 ---------------DGKFKKTLKGHTDEVFWVSFSPDGKIIASASADKTIRLW--DSFS 1519 Query: 361 AWEVDTLRGHMNNVSCVMFHAKQDIIVSNSEDK 459 + +L H + V V F+ ++ S S DK Sbjct: 1520 GNLIKSLPAHNDLVYSVNFNPDGSMLASTSADK 1552 Score = 54.3 bits (129), Expect = 2e-07 Identities = 40/152 (26%), Positives = 60/152 (39%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 ++W+ Q + L GH +V SF P + SAS D+T+++W I Sbjct: 1222 KLWHRQDGKLLKTLNGHQDWVNSLSFSPDGKTLASASADKTIKLWRI------------- 1268 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTK 360 D + L+GH+ V +F I S + D +KLW + Sbjct: 1269 --------------ADGKLVKTLKGHNDSVWDVNFSSDGKAIASASRDNTIKLWNRHGI- 1313 Query: 361 AWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 E++T GH V V F +II S S D Sbjct: 1314 --ELETFTGHSGGVYAVNFLPDSNIIASASLD 1343 Score = 48.1 bits (113), Expect = 1e-05 Identities = 34/135 (25%), Positives = 56/135 (41%), Gaps = 14/135 (10%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVW-------------DI 141 R+W+ S + L HN V +F+P ++ S S D+TV++W Sbjct: 1513 RLWDSFSGNLIKSLPAHNDLVYSVNFNPDGSMLASTSADKTVKLWRSHDGHLLHTFSGHS 1572 Query: 142 GALRKKTVSPADD-IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGA 318 + + SP I ++ T +D + L H GV A F P ++SG+ Sbjct: 1573 NVVYSSSFSPDGRYIASASEDKTVKIWQIDGHLLTTLPQHQAGVMSAIFSPDGKTLISGS 1632 Query: 319 DDRQVKLWRMNDTKA 363 D K+WR + +A Sbjct: 1633 LDTTTKIWRFDSQQA 1647 Score = 32.3 bits (72), Expect = 0.67 Identities = 21/69 (30%), Positives = 30/69 (43%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 +IW + L H VM A F P ++S SLD T ++W + + KT Sbjct: 1597 KIWQIDGHL-LTTLPQHQAGVMSAIFSPDGKTLISGSLDTTTKIWRFDSQQAKT------ 1649 Query: 181 IMRLTQMNT 207 +QMNT Sbjct: 1650 ----SQMNT 1654
>TUP12_SCHPO (Q9UUG8) Transcriptional repressor tup12| Length = 586 Score = 59.7 bits (143), Expect = 4e-09 Identities = 46/183 (25%), Positives = 72/183 (39%), Gaps = 23/183 (12%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 RIW+ + +LTGH + F +VS S D+TV +WD+ A +K + DD Sbjct: 359 RIWDIAQKRVYRLLTGHEQEIYSLDFSKDGKTLVSGSGDRTVCLWDVEAGEQKLILHTDD 418 Query: 181 IMRLTQMNTD----LFGGVDAVVKY---------VLEGHDRGVNWASFHPTLPLIVSGAD 321 + + D G +D V++ L GH+ V +F P +VSG+ Sbjct: 419 GVTTVMFSPDGQFIAAGSLDKVIRIWTSSGTLVEQLHGHEESVYSVAFSPDGKYLVSGSL 478 Query: 322 DRQVKLWRMNDTKAWE----------VDTLRGHMNNVSCVMFHAKQDIIVSNSEDKAFAS 471 D +KLW + T GH + + V I+S S+D+ Sbjct: 479 DNTIKLWELQCVSNVAPSMYKEGGICKQTFTGHKDFILSVTVSPDGKWIISGSKDRTIQF 538 Query: 472 GMP 480 P Sbjct: 539 WSP 541 Score = 48.1 bits (113), Expect = 1e-05 Identities = 35/145 (24%), Positives = 60/145 (41%), Gaps = 27/145 (18%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI------------- 141 RIW S T V L GH V +F P +VS SLD T+++W++ Sbjct: 442 RIWT-SSGTLVEQLHGHEESVYSVAFSPDGKYLVSGSLDNTIKLWELQCVSNVAPSMYKE 500 Query: 142 GALRKKTVSPADDIMRLTQMNTD----LFGGVDAVVKY----------VLEGHDRGVNWA 279 G + K+T + D + ++ D + G D +++ L+GH+ V Sbjct: 501 GGICKQTFTGHKDFILSVTVSPDGKWIISGSKDRTIQFWSPDSPHSQLTLQGHNNSVISV 560 Query: 280 SFHPTLPLIVSGADDRQVKLWRMND 354 + P +G+ D + ++W D Sbjct: 561 AVSPNGHCFATGSGDLRARIWSYED 585 Score = 42.7 bits (99), Expect = 5e-04 Identities = 39/154 (25%), Positives = 59/154 (38%), Gaps = 21/154 (13%) Frame = +1 Query: 58 YVMCASFHPKEDLVVSASLDQTVRVWDIGALR---------------------KKTVSPA 174 YV +F P + + DQ +R+WDI R K VS + Sbjct: 336 YVRSVAFSPDGKYLATGVEDQQIRIWDIAQKRVYRLLTGHEQEIYSLDFSKDGKTLVSGS 395 Query: 175 DDIMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMND 354 D T V+A + ++ D GV F P I +G+ D+ +++W + Sbjct: 396 GD-------RTVCLWDVEAGEQKLILHTDDGVTTVMFSPDGQFIAAGSLDKVIRIWTSSG 448 Query: 355 TKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 T V+ L GH +V V F +VS S D Sbjct: 449 TL---VEQLHGHEESVYSVAFSPDGKYLVSGSLD 479 Score = 31.2 bits (69), Expect = 1.5 Identities = 16/67 (23%), Positives = 32/67 (47%) Frame = +1 Query: 259 DRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDII 438 D V +F P + +G +D+Q+++W + + + + L GH + + F + Sbjct: 334 DLYVRSVAFSPDGKYLATGVEDQQIRIWDIAQKRVYRL--LTGHEQEIYSLDFSKDGKTL 391 Query: 439 VSNSEDK 459 VS S D+ Sbjct: 392 VSGSGDR 398
>POF11_SCHPO (Q09855) F-box/WD-repeat protein pof11| Length = 506 Score = 59.3 bits (142), Expect = 5e-09 Identities = 42/154 (27%), Positives = 70/154 (45%), Gaps = 2/154 (1%) Frame = +1 Query: 4 IWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDI 183 +W+ SR + L GH+ V+C F + +L+VS S D T+ +WD R V Sbjct: 245 VWDVNSRFILYKLYGHSGSVLCLDFCRRRNLLVSGSSDSTIIIWDWQNRRPLKV------ 298 Query: 184 MRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKA 363 FG D V+ V+ + I+S + D ++WR++ T Sbjct: 299 ---------YFGHTDNVLGVVVSEN--------------YIISSSRDHTARVWRLDATSP 335 Query: 364 WE--VDTLRGHMNNVSCVMFHAKQDIIVSNSEDK 459 E + LRGH+ +V+ V + +K +IV+ S D+ Sbjct: 336 AEACMHVLRGHLASVNSVQYSSKTGLIVTASSDR 369 Score = 43.9 bits (102), Expect = 2e-04 Identities = 39/156 (25%), Positives = 67/156 (42%), Gaps = 4/156 (2%) Frame = +1 Query: 1 RIWNWQSRT----CVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVS 168 R+W + + C+ VL GH V + K L+V+AS D+T+R WDI Sbjct: 326 RVWRLDATSPAEACMHVLRGHLASVNSVQYSSKTGLIVTASSDRTLRTWDI--------- 376 Query: 169 PADDIMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRM 348 +R ++ H RG+ A ++ IVSG+ D ++++ Sbjct: 377 TTGHCIR------------------IIHAHQRGIACAQYNG--KFIVSGSSDLTIRIFEA 416 Query: 349 NDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 + K + L+GH + + V F+ ++ IVS D Sbjct: 417 SSGKLLRM--LQGHEDLIRTVRFNDEK--IVSGGYD 448
>PRL2_ARATH (Q39190) PP1/PP2A phosphatases pleiotropic regulator PRL2| Length = 479 Score = 59.3 bits (142), Expect = 5e-09 Identities = 39/161 (24%), Positives = 62/161 (38%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 + W+ + + GH H V C + HP D+V++ D RVWDI + V P Sbjct: 237 KCWDLEQNKVIRSYHGHLHGVYCLALHPTLDVVLTGGRDSVCRVWDIRTKMQIFVLP--- 293 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTK 360 HD V PT P +++G+ D +K W + K Sbjct: 294 -------------------------HDSDVFSVLARPTDPQVITGSHDSTIKFWDLRYGK 328 Query: 361 AWEVDTLRGHMNNVSCVMFHAKQDIIVSNSEDKAFASGMPQ 483 + + T+ H V + H K++ VS S D +P+ Sbjct: 329 S--MATITNHKKTVRAMALHPKENDFVSASADNIKKFSLPK 367 Score = 56.6 bits (135), Expect = 3e-08 Identities = 33/140 (23%), Positives = 56/140 (40%) Frame = +1 Query: 37 VLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDIMRLTQMNTDLF 216 VL GH +V +F P + + S D+T+++WD+ Sbjct: 165 VLQGHLGWVRSVAFDPSNEWFCTGSADRTIKIWDVAT----------------------- 201 Query: 217 GGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVDTLRGHMN 396 V+K L GH V + + S DD+QVK W + K + + GH++ Sbjct: 202 ----GVLKLTLTGHIGQVRGLAVSNRHTYMFSAGDDKQVKCWDLEQNKV--IRSYHGHLH 255 Query: 397 NVSCVMFHAKQDIIVSNSED 456 V C+ H D++++ D Sbjct: 256 GVYCLALHPTLDVVLTGGRD 275
>PLRG1_RAT (Q9WUC8) Pleiotropic regulator 1| Length = 514 Score = 59.3 bits (142), Expect = 5e-09 Identities = 45/155 (29%), Positives = 74/155 (47%), Gaps = 15/155 (9%) Frame = +1 Query: 37 VLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKT-----VSPADDIMRLTQM 201 V++GH +V C + P V+ S D+T+++WD+ + + K +S ++ T+ Sbjct: 199 VISGHLGWVRCIAVEPGNQWFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRS 258 Query: 202 NTDLFGGVDAVVK-YVLE---------GHDRGVNWASFHPTLPLIVSGADDRQVKLWRMN 351 G D VK + LE GH V HPT+ ++V+ + D ++W + Sbjct: 259 PYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDVR 318 Query: 352 DTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 TKA V TL GH N V+ V A + I++ S D Sbjct: 319 -TKA-SVHTLSGHTNAVATVRCQAAEPQIITGSHD 351 Score = 46.2 bits (108), Expect = 5e-05 Identities = 36/152 (23%), Positives = 55/152 (36%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 + W+ + + GH V HP D++V+ S D T R+WD+ K +V Sbjct: 271 KCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDVRT--KASV----- 323 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTK 360 + L GH V P I++G+ D ++LW + K Sbjct: 324 --------------------HTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVAGK 363 Query: 361 AWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 TL H +V V+ H S S D Sbjct: 364 TRV--TLTNHKKSVRAVVLHPLHYTFASGSPD 393 Score = 43.5 bits (101), Expect = 3e-04 Identities = 33/128 (25%), Positives = 63/128 (49%), Gaps = 14/128 (10%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKK-TVSPAD 177 RIW+ +++ V L+GH + V E +++ S D T+R+WD+ A + + T++ Sbjct: 313 RIWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVAGKTRVTLTNHK 372 Query: 178 DIMRLTQMN----TDLFGGVDAVVKYV---------LEGHDRGVNWASFHPTLPLIVSGA 318 +R ++ T G D + ++ L GH+ +N + + T ++VSGA Sbjct: 373 KSVRAVVLHPLHYTFASGSPDNIKQWKFPDGGFIQNLSGHNAIINTLAVN-TDGVLVSGA 431 Query: 319 DDRQVKLW 342 D+ + LW Sbjct: 432 DNGTMHLW 439
>PLRG1_HUMAN (O43660) Pleiotropic regulator 1| Length = 514 Score = 59.3 bits (142), Expect = 5e-09 Identities = 45/155 (29%), Positives = 74/155 (47%), Gaps = 15/155 (9%) Frame = +1 Query: 37 VLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKT-----VSPADDIMRLTQM 201 V++GH +V C + P V+ S D+T+++WD+ + + K +S ++ T+ Sbjct: 199 VISGHLGWVRCIAVEPGNQWFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRS 258 Query: 202 NTDLFGGVDAVVK-YVLE---------GHDRGVNWASFHPTLPLIVSGADDRQVKLWRMN 351 G D VK + LE GH V HPT+ ++V+ + D ++W + Sbjct: 259 PYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDVR 318 Query: 352 DTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 TKA V TL GH N V+ V A + I++ S D Sbjct: 319 -TKA-SVHTLSGHTNAVATVRCQAAEPQIITGSHD 351 Score = 47.8 bits (112), Expect = 2e-05 Identities = 36/152 (23%), Positives = 56/152 (36%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 + W+ + + GH V HP D++V+ S D T R+WD+ K +V Sbjct: 271 KCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDVRT--KASV----- 323 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTK 360 + L GH V P I++G+ D ++LW + K Sbjct: 324 --------------------HTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVAGK 363 Query: 361 AWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 TL H +V V+ H + S S D Sbjct: 364 TRV--TLTNHKKSVRAVVLHPRHYTFASGSPD 393 Score = 42.4 bits (98), Expect = 7e-04 Identities = 32/128 (25%), Positives = 62/128 (48%), Gaps = 14/128 (10%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKK-TVSPAD 177 RIW+ +++ V L+GH + V E +++ S D T+R+WD+ A + + T++ Sbjct: 313 RIWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVAGKTRVTLTNHK 372 Query: 178 DIMRLTQMN----TDLFGGVDAVVKYV---------LEGHDRGVNWASFHPTLPLIVSGA 318 +R ++ T G D + ++ L GH+ +N + + ++VSGA Sbjct: 373 KSVRAVVLHPRHYTFASGSPDNIKQWKFPDGSFIQNLSGHNAIINTLTVNSD-GVLVSGA 431 Query: 319 DDRQVKLW 342 D+ + LW Sbjct: 432 DNGTMHLW 439
>LIS1_DROME (Q7KNS3) Lissencephaly-1 homolog (Lissencephaly1) (Dlis1) (DLis-1)| Length = 411 Score = 59.3 bits (142), Expect = 5e-09 Identities = 38/173 (21%), Positives = 66/173 (38%), Gaps = 20/173 (11%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKE--------------------DLVVSASLDQ 120 R+W S+ C L H H V C ++ P+ + S S D+ Sbjct: 260 RVWLTNSKDCKVELRDHEHTVECIAWAPEAAASAINEAAGADNKKGHHQGPFLASGSRDK 319 Query: 121 TVRVWDIGALRKKTVSPADDIMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLP 300 T+R+WD+ + L GHD V +FHP Sbjct: 320 TIRIWDVSV---------------------------GLCLLTLSGHDNWVRGLAFHPGGK 352 Query: 301 LIVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSEDK 459 +VS +DD+ +++W + + + + TL H + + + FH ++S S D+ Sbjct: 353 YLVSASDDKTIRVWDLRNKRC--MKTLYAHQHFCTSIDFHKAHPYVISGSVDQ 403 Score = 57.8 bits (138), Expect = 1e-08 Identities = 45/157 (28%), Positives = 66/157 (42%), Gaps = 17/157 (10%) Frame = +1 Query: 40 LTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI--GALRKKTVSPADDIM--------- 186 LTGH + FHP L+VSAS D T+R+WD G + D + Sbjct: 104 LTGHRASITRVIFHPIFALMVSASEDATIRIWDFETGEYERSLKGHTDSVQDVAFDAQGK 163 Query: 187 RLTQMNTDL------FGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRM 348 L + DL F +K + GHD V+ +F P ++S + DR +K+W + Sbjct: 164 LLASCSADLSIKLWDFQQSYECIK-TMHGHDHNVSSVAFVPAGDYVLSASRDRTIKMWEV 222 Query: 349 NDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSEDK 459 + V T GH V V H + I + S D+ Sbjct: 223 --ATGYCVKTYTGHREWVRMVRVHIEGSIFATCSNDQ 257 Score = 56.6 bits (135), Expect = 3e-08 Identities = 37/114 (32%), Positives = 52/114 (45%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 RIW+ C+ L+GH+++V +FHP +VSAS D+T+RVWD LR K Sbjct: 322 RIWDVSVGLCLLTLSGHDNWVRGLAFHPGGKYLVSASDDKTIRVWD---LRNKRC----- 373 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLW 342 M T L H FH P ++SG+ D+ VK+W Sbjct: 374 ------MKT-------------LYAHQHFCTSIDFHKAHPYVISGSVDQTVKVW 408 Score = 56.2 bits (134), Expect = 4e-08 Identities = 48/191 (25%), Positives = 85/191 (44%), Gaps = 38/191 (19%) Frame = +1 Query: 1 RIWNWQ-SRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIG-ALRKKTVSPA 174 ++W++Q S C+ + GH+H V +F P D V+SAS D+T+++W++ KT + Sbjct: 175 KLWDFQQSYECIKTMHGHDHNVSSVAFVPAGDYVLSASRDRTIKMWEVATGYCVKTYTGH 234 Query: 175 DDIMRLTQMNTDLFGGVDAV----------------VKYVLEGHDRGVN---WA------ 279 + +R+ +++ + G + A K L H+ V WA Sbjct: 235 REWVRMVRVHIE--GSIFATCSNDQTIRVWLTNSKDCKVELRDHEHTVECIAWAPEAAAS 292 Query: 280 -----------SFHPTLPLIVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAK 426 H P + SG+ D+ +++W ++ + TL GH N V + FH Sbjct: 293 AINEAAGADNKKGHHQGPFLASGSRDKTIRIWDVSVGLC--LLTLSGHDNWVRGLAFHPG 350 Query: 427 QDIIVSNSEDK 459 +VS S+DK Sbjct: 351 GKYLVSASDDK 361 Score = 47.8 bits (112), Expect = 2e-05 Identities = 17/46 (36%), Positives = 28/46 (60%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWD 138 R+W+ +++ C+ L H H+ FH V+S S+DQTV+VW+ Sbjct: 364 RVWDLRNKRCMKTLYAHQHFCTSIDFHKAHPYVISGSVDQTVKVWE 409 Score = 45.1 bits (105), Expect = 1e-04 Identities = 24/73 (32%), Positives = 41/73 (56%) Frame = +1 Query: 238 KYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMF 417 K+ L GH + FHP L+VS ++D +++W +T +E +L+GH ++V V F Sbjct: 101 KFSLTGHRASITRVIFHPIFALMVSASEDATIRIWDF-ETGEYE-RSLKGHTDSVQDVAF 158 Query: 418 HAKQDIIVSNSED 456 A+ ++ S S D Sbjct: 159 DAQGKLLASCSAD 171
>WD51B_MOUSE (Q8BHD1) WD-repeat protein 51B| Length = 476 Score = 59.3 bits (142), Expect = 5e-09 Identities = 46/169 (27%), Positives = 73/169 (43%), Gaps = 17/169 (10%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 ++W+ + + L H H+V CA F P L+VS S D+T+++WD K+ V+ D Sbjct: 127 KVWSMFRQRFLYSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIWD--TTNKQCVNNFSD 184 Query: 181 ---IMRLTQMNTD----LFGGVDAVVK----------YVLEGHDRGVNWASFHPTLPLIV 309 N + G D VK + H GVN SFHP +V Sbjct: 185 SVGFANFVDFNPNGTCIASAGSDHAVKIWDIRMNKLLQHYQVHSCGVNCLSFHPLGNSLV 244 Query: 310 SGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 + + D VK+ + + + + TL+GH V V F +++ S D Sbjct: 245 TASSDGTVKMLDLIEGRL--IYTLQGHTGPVFTVSFSKDGELLTSGGAD 291 Score = 47.0 bits (110), Expect = 3e-05 Identities = 37/152 (24%), Positives = 60/152 (39%) Frame = +1 Query: 4 IWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDI 183 +W+ + GH V F P+ +L+ SAS D+TVR+W + K + Sbjct: 44 LWSLKPHARAYRYVGHKDVVTSLQFSPQGNLLASASRDRTVRLWVLDRKGKSS------- 96 Query: 184 MRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKA 363 + H V F L+V+ ++D+ +K+W M + Sbjct: 97 --------------------EFKAHTAPVRSVDFSADGQLLVTASEDKSIKVWSMFRQRF 136 Query: 364 WEVDTLRGHMNNVSCVMFHAKQDIIVSNSEDK 459 + +L H + V C F +IVS SEDK Sbjct: 137 --LYSLYRHTHWVRCAKFSPDGRLIVSCSEDK 166 Score = 45.4 bits (106), Expect = 8e-05 Identities = 32/117 (27%), Positives = 49/117 (41%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 +IW+ + + H+ V C SFHP + +V+AS D TV++ D+ Sbjct: 211 KIWDIRMNKLLQHYQVHSCGVNCLSFHPLGNSLVTASSDGTVKMLDL------------- 257 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMN 351 ++ + Y L+GH V SF L+ SG D QV +WR N Sbjct: 258 --------------IEGRLIYTLQGHTGPVFTVSFSKDGELLTSGGADAQVLIWRTN 300 Score = 30.0 bits (66), Expect = 3.3 Identities = 18/79 (22%), Positives = 37/79 (46%), Gaps = 1/79 (1%) Frame = +1 Query: 226 DAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMN-DTKAWEVDTLRGHMNNV 402 D +++ +GH + A F P I + + D + LW + +A+ GH + V Sbjct: 7 DPILERSFKGHKAAITSADFSPNCKQIATASWDTFLMLWSLKPHARAYR---YVGHKDVV 63 Query: 403 SCVMFHAKQDIIVSNSEDK 459 + + F + +++ S S D+ Sbjct: 64 TSLQFSPQGNLLASASRDR 82
>WDR37_HUMAN (Q9Y2I8) WD-repeat protein 37| Length = 494 Score = 58.9 bits (141), Expect = 7e-09 Identities = 50/208 (24%), Positives = 79/208 (37%), Gaps = 56/208 (26%) Frame = +1 Query: 4 IWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDI 183 +W+ ++ C+ GH V FHP E L ++AS DQT +W A++ T P D Sbjct: 183 LWSIETGKCLVKYAGHVGSVNSIKFHPSEQLALTASGDQTAHIWRY-AVQLPTPQPVADT 241 Query: 184 ------------------------------MRLTQMNTD---------LFGGVDAV---- 234 + LT + + L GG AV Sbjct: 242 SISGEDEVECSDKDEPDLDGDVSSDCPTIRVPLTSLKSHQGVVIASDWLVGGKQAVTASW 301 Query: 235 -------------VKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVD 375 + + L GHD+ + HPT L+V+ + D +LW D V+ Sbjct: 302 DRTANLYDVETSELVHSLTGHDQELTHCCTHPTQRLVVTSSRDTTFRLWDFRDPSIHSVN 361 Query: 376 TLRGHMNNVSCVMFHAKQDIIVSNSEDK 459 +GH + V+ +F D +VS S+D+ Sbjct: 362 VFQGHTDTVTSAVF-TVGDNVVSGSDDR 388 Score = 43.1 bits (100), Expect = 4e-04 Identities = 32/120 (26%), Positives = 54/120 (45%) Frame = +1 Query: 4 IWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDI 183 +++ ++ V LTGH+ + HP + LVV++S D T R+WD R ++ + Sbjct: 307 LYDVETSELVHSLTGHDQELTHCCTHPTQRLVVTSSRDTTFRLWD---FRDPSIHSVN-- 361 Query: 184 MRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKA 363 V +GH V A F +VSG+DDR VK+W + + ++ Sbjct: 362 --------------------VFQGHTDTVTSAVF-TVGDNVVSGSDDRTVKVWDLKNMRS 400
>GBLP_DICDI (P46800) Guanine nucleotide-binding protein beta subunit-like| protein Length = 329 Score = 58.2 bits (139), Expect = 1e-08 Identities = 45/157 (28%), Positives = 70/157 (44%), Gaps = 18/157 (11%) Frame = +1 Query: 40 LTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI--GALRKKTVSPADDIMRLTQMNTD- 210 L GH+H+V +S S D T+R+WDI G + D+M + + + Sbjct: 66 LKGHSHFVQDVVISHDGQFALSGSWDNTLRLWDITKGVSTRLFKGHTQDVMSVAFSSDNR 125 Query: 211 --LFGGVDAVVK---------YVLEGHDRGVNWAS---FHPTLPLIVSGADDRQVKLWRM 348 + G DA +K + LEG + +W S F P P IVSG+ D +VK+W Sbjct: 126 QIISGSRDATIKVWNTLGECKFTLEGPEAHQDWVSCIRFSPNTPTIVSGSWDNKVKIW-- 183 Query: 349 NDTKAWEVD-TLRGHMNNVSCVMFHAKQDIIVSNSED 456 D K+++ + TL H V+ V + S +D Sbjct: 184 -DIKSFKCNHTLTDHTGYVNTVTISPDGSLCASGGKD 219 Score = 48.5 bits (114), Expect = 9e-06 Identities = 40/164 (24%), Positives = 66/164 (40%), Gaps = 22/164 (13%) Frame = +1 Query: 31 VAVLTGHNHYVMCASFHPKE-DLVVSASLDQTVRVWDIGALRKKTVSPA----------- 174 V L GHN +V + P+ D ++S+S D+TV VW + + A Sbjct: 14 VGSLVGHNGFVTSIAVSPENPDTIISSSRDKTVMVWQLTPTDATSPGKAHRSLKGHSHFV 73 Query: 175 DDIMRLTQMNTDLFGGVDAVVKY----------VLEGHDRGVNWASFHPTLPLIVSGADD 324 D++ L G D ++ + +GH + V +F I+SG+ D Sbjct: 74 QDVVISHDGQFALSGSWDNTLRLWDITKGVSTRLFKGHTQDVMSVAFSSDNRQIISGSRD 133 Query: 325 RQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 +K+W + ++ H + VSC+ F IVS S D Sbjct: 134 ATIKVWNTLGECKFTLEGPEAHQDWVSCIRFSPNTPTIVSGSWD 177 Score = 39.7 bits (91), Expect = 0.004 Identities = 30/123 (24%), Positives = 42/123 (34%), Gaps = 3/123 (2%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTG---HNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSP 171 ++WN C L G H +V C F P +VS S D V++WDI + + Sbjct: 137 KVWNTLGE-CKFTLEGPEAHQDWVSCIRFSPNTPTIVSGSWDNKVKIWDIKSFK------ 189 Query: 172 ADDIMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMN 351 + L H VN + P L SG D LW ++ Sbjct: 190 ---------------------CNHTLTDHTGYVNTVTISPDGSLCASGGKDTFACLWELS 228 Query: 352 DTK 360 K Sbjct: 229 SGK 231
>POF1_SCHPO (P87053) F-box/WD-repeat protein pof1 (Skp1-binding protein 1)| Length = 605 Score = 58.2 bits (139), Expect = 1e-08 Identities = 46/164 (28%), Positives = 76/164 (46%), Gaps = 15/164 (9%) Frame = +1 Query: 10 NWQSRTC-VAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTV----SPA 174 NW+ C VL+GH+ VMC +++ S S D T+R+W++ ++ + S Sbjct: 258 NWRHGRCRQVVLSGHSDGVMCLQL--VRNILASGSYDATIRLWNLATFQQVALLEGHSSG 315 Query: 175 DDIMRLTQMNTDLFGGVDAVVKY----------VLEGHDRGVNWASFHPTLPLIVSGADD 324 ++ Q + G +D ++ +L GH V +F TL +VSG+ D Sbjct: 316 VTCLQFDQCKL-ISGSMDKTIRIWNYRTSECISILHGHTDSVLCLTFDSTL--LVSGSAD 372 Query: 325 RQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 VKLW + K TLRGH V+ V + +++S S+D Sbjct: 373 CTVKLWHFSGGKR---ITLRGHTGPVNSVRIIRDRGLVLSGSDD 413 Score = 53.5 bits (127), Expect = 3e-07 Identities = 32/116 (27%), Positives = 51/116 (43%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 RIWN+++ C+++L GH V+C +F L+VS S D TV++W ++ T Sbjct: 336 RIWNYRTSECISILHGHTDSVLCLTF--DSTLLVSGSADCTVKLWHFSGGKRIT------ 387 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRM 348 L GH VN L++SG+DD +K+W + Sbjct: 388 ----------------------LRGHTGPVNSVRIIRDRGLVLSGSDDSTIKIWSL 421 Score = 40.4 bits (93), Expect = 0.002 Identities = 38/156 (24%), Positives = 68/156 (43%), Gaps = 21/156 (13%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPA-- 174 +IW+ ++ TC+ + H V + + + S SLD T++ WDI +KK V Sbjct: 417 KIWSLETNTCLHTFSAHIGPVQSLAL--ADSRLFSCSLDGTIKQWDIE--KKKCVHTLFG 472 Query: 175 --DDIMRLTQMNTDLFGGV-DAVVK--------YVLEGHDRGVNWASFHPTLPLIVSGAD 321 + + + + L G D VVK + L+ H V + +VSG++ Sbjct: 473 HIEGVWEIAADHLRLISGAHDGVVKVWEACECVHTLKNHSEPVTSVALGDCE--VVSGSE 530 Query: 322 DRQVKLWRMND--------TKAWEVDTLRGHMNNVS 405 D ++ LW N+ T++ + +L G +N S Sbjct: 531 DGKIYLWLFNNAPNESPVSTQSVPISSLNGQRSNSS 566
>KMHA_DICDI (P42527) Myosin heavy chain kinase A (EC 2.7.11.7) (MHCK A)| Length = 1146 Score = 57.8 bits (138), Expect = 1e-08 Identities = 47/160 (29%), Positives = 75/160 (46%), Gaps = 15/160 (9%) Frame = +1 Query: 28 CVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRK-KTVSPADD--IMRLTQ 198 C+ L GH V C + K + S S D+T++VWD+ ++ K+ I L Sbjct: 946 CIETLVGHTGEVNCVVANEK--YLFSCSYDKTIKVWDLSTFKEIKSFEGVHTKYIKTLAL 1003 Query: 199 MNTDLFGGVDAVVKYV-----------LEGHDRGVNWASFHPTLPLIVSGADDRQVKLWR 345 LF G + + YV ++GH+ V S H T + S + D +K+W Sbjct: 1004 SGRYLFSGGNDQIIYVWDTETLSMLFNMQGHEDWV--LSLHCTASYLFSTSKDNVIKIWD 1061 Query: 346 MNDTKAWEVDTLRGHMNNV-SCVMFHAKQDIIVSNSEDKA 462 +++ +DTL+GH N+V SCV+ K + S SED + Sbjct: 1062 LSNFSC--IDTLKGHWNSVSSCVV---KDRYLYSGSEDNS 1096 Score = 33.5 bits (75), Expect = 0.30 Identities = 30/144 (20%), Positives = 55/144 (38%) Frame = +1 Query: 4 IWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDI 183 +W+ ++ + + + GH +V+ S H + S S D +++WD+ Sbjct: 1019 VWDTETLSMLFNMQGHEDWVL--SLHCTASYLFSTSKDNVIKIWDLSN------------ 1064 Query: 184 MRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKA 363 F +D L+GH V+ + SG++D +K+W + DT Sbjct: 1065 ----------FSCID-----TLKGHWNSVSSCVVKDR--YLYSGSEDNSIKVWDL-DTLE 1106 Query: 364 WEVDTLRGHMNNVSCVMFHAKQDI 435 + H V C+M Q I Sbjct: 1107 CVYTIPKSHSLGVKCLMVFNNQII 1130 Score = 32.7 bits (73), Expect = 0.52 Identities = 16/50 (32%), Positives = 29/50 (58%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGAL 150 +IW+ + +C+ L GH + V +S K+ + S S D +++VWD+ L Sbjct: 1058 KIWDLSNFSCIDTLKGHWNSV--SSCVVKDRYLYSGSEDNSIKVWDLDTL 1105 Score = 29.6 bits (65), Expect = 4.4 Identities = 31/144 (21%), Positives = 54/144 (37%) Frame = +1 Query: 28 CVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDIMRLTQMNT 207 CV+ + V +F + L+ + D T RV+D+ K Sbjct: 861 CVSTIQSFRERVNSIAFFDNQKLLCAGYGDGTYRVFDVNDNWK----------------- 903 Query: 208 DLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVDTLRG 387 Y + GH + + + + S + +V + R +TK ++TL G Sbjct: 904 ---------CLYTVNGHRKSIESIACNSNYIFTSSPDNTIKVHIIRSGNTKC--IETLVG 952 Query: 388 HMNNVSCVMFHAKQDIIVSNSEDK 459 H V+CV+ A + + S S DK Sbjct: 953 HTGEVNCVV--ANEKYLFSCSYDK 974
>Y163_SYNY3 (Q55563) Hypothetical WD-repeat protein sll0163| Length = 1693 Score = 57.4 bits (137), Expect = 2e-08 Identities = 46/165 (27%), Positives = 73/165 (44%), Gaps = 13/165 (7%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 R W+ + + LTGH+H+V A F+PK D +++ S D+T R+W ++ Sbjct: 1326 RQWDISQKDTIT-LTGHSHWVRNAHFNPKGDRLLTVSRDKTARLWTTEGECVAVLADHQG 1384 Query: 181 IMRLTQMNTD----LFGGVDAVVKY---------VLEGHDRGVNWASFHPTLPLIVSGAD 321 +R Q + D + G D + VL GH V F P IV+ + Sbjct: 1385 WVREGQFSPDGQWIVTGSADKTAQLWNVLGKKLTVLRGHQDAVLNVRFSPDSQYIVTASK 1444 Query: 322 DRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 D ++W N+T E+ LR + N+ F A IV+ S+D Sbjct: 1445 DGTARVW--NNT-GRELAVLRHYEKNIFAAEFSADGQFIVTASDD 1486 Score = 53.9 bits (128), Expect = 2e-07 Identities = 44/166 (26%), Positives = 73/166 (43%), Gaps = 13/166 (7%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWD-----IGALR---- 153 R+W+ S+ C AVL GH ++V A + P ++++S D T RVW +G LR Sbjct: 1203 RLWDLSSQ-CFAVLKGHQNWVNNALWSPDGQHIITSSSDGTARVWSRHGKCLGTLRGHDH 1261 Query: 154 ----KKTVSPADDIMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGAD 321 + I+ + NT + + +L GH + V A F + + + Sbjct: 1262 NIHGARFSLDGQKIVTYSTDNTARLWTKEGTLLTILRGHQKEVYDADFSADGRFVFTVSA 1321 Query: 322 DRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSEDK 459 D+ + W D + TL GH + V F+ K D +++ S DK Sbjct: 1322 DQTARQW---DISQKDTITLTGHSHWVRNAHFNPKGDRLLTVSRDK 1364 Score = 51.2 bits (121), Expect = 1e-06 Identities = 42/152 (27%), Positives = 63/152 (41%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 RIW++ R + L GH V A F P+ +L+ + S D T R+WD KTV+ Sbjct: 1531 RIWDFLGRPLLT-LAGHQSIVYQARFSPEGNLIATVSADHTARLWDRSG---KTVA---- 1582 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTK 360 VL GH V + P ++V+ ++D +LW D Sbjct: 1583 ---------------------VLYGHQGLVGTVDWSPDGQMLVTASNDGTARLW---DLS 1618 Query: 361 AWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 E+ TL GH N V F ++++S D Sbjct: 1619 GRELLTLEGHGNWVRSAEFSPDGRWVLTSSAD 1650 Score = 47.0 bits (110), Expect = 3e-05 Identities = 38/155 (24%), Positives = 61/155 (39%), Gaps = 13/155 (8%) Frame = +1 Query: 31 VAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDIMRLTQMNTD 210 VA L GH +V F P +V++ D T R+W+ + D +R + N Sbjct: 1089 VATLRGHEDWVRSVHFSPHHQFLVTSGQDNTARIWNFAGEQLTLCQGHADWVRNAEFNCH 1148 Query: 211 ----LFGGVDAVVKY---------VLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMN 351 L D + + +GH V A F P IV+ + D +LW Sbjct: 1149 GQILLTASRDGTARLWDLEGREIGLCQGHTSWVRNAQFSPDGQWIVTCSADGTARLW--- 1205 Query: 352 DTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 D + L+GH N V+ ++ I+++S D Sbjct: 1206 DLSSQCFAVLKGHQNWVNNALWSPDGQHIITSSSD 1240 Score = 44.7 bits (104), Expect = 1e-04 Identities = 43/165 (26%), Positives = 62/165 (37%), Gaps = 13/165 (7%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 R+WN R +AVL + + A F +V+AS D T +W+I + Sbjct: 1449 RVWNNTGRE-LAVLRHYEKNIFAAEFSADGQFIVTASDDNTAGIWEIVGREVGICRGHEG 1507 Query: 181 IMRLTQMNTD----LFGGVDAVVK---------YVLEGHDRGVNWASFHPTLPLIVSGAD 321 + Q + D L VD + L GH V A F P LI + + Sbjct: 1508 PVYFAQFSADSRYILTASVDNTARIWDFLGRPLLTLAGHQSIVYQARFSPEGNLIATVSA 1567 Query: 322 DRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 D +LW D V L GH V V + ++V+ S D Sbjct: 1568 DHTARLW---DRSGKTVAVLYGHQGLVGTVDWSPDGQMLVTASND 1609 Score = 43.9 bits (102), Expect = 2e-04 Identities = 32/114 (28%), Positives = 45/114 (39%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 R+W+ +T VAVL GH V + P ++V+AS D T R+WD+ T Sbjct: 1572 RLWDRSGKT-VAVLYGHQGLVGTVDWSPDGQMLVTASNDGTARLWDLSGRELLT------ 1624 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLW 342 LEGH V A F P +++ + D KLW Sbjct: 1625 ----------------------LEGHGNWVRSAEFSPDGRWVLTSSADGTAKLW 1656 Score = 35.4 bits (80), Expect = 0.080 Identities = 21/71 (29%), Positives = 32/71 (45%) Frame = +1 Query: 244 VLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHA 423 VL GH + + + + D VKLW+ + EV TLRGH + V V F Sbjct: 1050 VLRGHQEAITALDWSADGQYFATASADHTVKLWQRHGE---EVATLRGHEDWVRSVHFSP 1106 Query: 424 KQDIIVSNSED 456 +V++ +D Sbjct: 1107 HHQFLVTSGQD 1117 Score = 35.0 bits (79), Expect = 0.10 Identities = 35/164 (21%), Positives = 61/164 (37%), Gaps = 13/164 (7%) Frame = +1 Query: 4 IWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDI 183 +W++ + VL GH + + +AS D TV++W T+ +D Sbjct: 1040 LWSFHGEL-INVLRGHQEAITALDWSADGQYFATASADHTVKLWQRHGEEVATLRGHEDW 1098 Query: 184 MRLT-------------QMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADD 324 +R Q NT + +GH V A F+ ++++ + D Sbjct: 1099 VRSVHFSPHHQFLVTSGQDNTARIWNFAGEQLTLCQGHADWVRNAEFNCHGQILLTASRD 1158 Query: 325 RQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 +LW D + E+ +GH + V F IV+ S D Sbjct: 1159 GTARLW---DLEGREIGLCQGHTSWVRNAQFSPDGQWIVTCSAD 1199
>WD51A_HUMAN (Q8NBT0) WD-repeat protein 51A| Length = 407 Score = 56.6 bits (135), Expect = 3e-08 Identities = 33/132 (25%), Positives = 55/132 (41%), Gaps = 15/132 (11%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI------------- 141 ++W+ SR CV H +V FHP + +A +D TV+VWD+ Sbjct: 170 KLWDKSSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHS 229 Query: 142 GALRKKTVSPADDIMRLTQMNTDL--FGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSG 315 A+ + P+ + + ++ L ++ + Y L GH +F T SG Sbjct: 230 AAVNGLSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFASG 289 Query: 316 ADDRQVKLWRMN 351 D QV +W+ N Sbjct: 290 GSDEQVMVWKSN 301 Score = 56.6 bits (135), Expect = 3e-08 Identities = 48/166 (28%), Positives = 69/166 (41%), Gaps = 15/166 (9%) Frame = +1 Query: 4 IWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD- 180 +W+ + ++ TGH V C +F P L+ S S D+TVR+W + TV A Sbjct: 45 VWHMKPQSRAYRFTGHKDAVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTA 104 Query: 181 IMRLTQMNTD----LFGGVDAVVK----------YVLEGHDRGVNWASFHPTLPLIVSGA 318 +R +D + D VK + L H V A F P LIVS + Sbjct: 105 TVRSVHFCSDGQSFVTASDDKTVKVWATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSAS 164 Query: 319 DDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 DD+ VKLW + + V + H V+ V FH I + D Sbjct: 165 DDKTVKLWDKSSREC--VHSYCEHGGFVTYVDFHPSGTCIAAAGMD 208 Score = 52.8 bits (125), Expect = 5e-07 Identities = 45/171 (26%), Positives = 77/171 (45%), Gaps = 18/171 (10%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 ++W + + L+ H ++V CA F P L+VSAS D+TV++WD + R+ S + Sbjct: 128 KVWATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKSS-RECVHSYCEH 186 Query: 181 IMRLTQMNTDLFG------GVDAVVK------------YVLEGHDRGVNWASFHPTLPLI 306 +T ++ G G+D VK Y L H VN SFHP+ + Sbjct: 187 GGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQL--HSAAVNGLSFHPSGNYL 244 Query: 307 VSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSEDK 459 ++ + D +K+ + + + + TL GH + V F + S D+ Sbjct: 245 ITASSDSTLKILDLMEGRL--LYTLHGHQGPATTVAFSRTGEYFASGGSDE 293 Score = 41.2 bits (95), Expect = 0.001 Identities = 35/138 (25%), Positives = 49/138 (35%) Frame = +1 Query: 46 GHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDIMRLTQMNTDLFGGV 225 GH V C F + S S+D + VW + P R T Sbjct: 17 GHRDAVTCVDFSINTKQLASGSMDSCLMVWH--------MKPQSRAYRFT---------- 58 Query: 226 DAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVS 405 GH V +F P+ L+ SG+ D+ V++W N E R H V Sbjct: 59 ---------GHKDAVTCVNFSPSGHLLASGSRDKTVRIWVPN--VKGESTVFRAHTATVR 107 Query: 406 CVMFHAKQDIIVSNSEDK 459 V F + V+ S+DK Sbjct: 108 SVHFCSDGQSFVTASDDK 125 Score = 33.9 bits (76), Expect = 0.23 Identities = 21/78 (26%), Positives = 34/78 (43%), Gaps = 1/78 (1%) Frame = +1 Query: 250 EGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMN-DTKAWEVDTLRGHMNNVSCVMFHAK 426 +GH V F + SG+ D + +W M ++A+ GH + V+CV F Sbjct: 16 KGHRDAVTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYR---FTGHKDAVTCVNFSPS 72 Query: 427 QDIIVSNSEDKAFASGMP 480 ++ S S DK +P Sbjct: 73 GHLLASGSRDKTVRIWVP 90
>WD51A_BOVIN (Q2TBP4) WD-repeat protein 51A| Length = 407 Score = 56.6 bits (135), Expect = 3e-08 Identities = 33/132 (25%), Positives = 55/132 (41%), Gaps = 15/132 (11%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI------------- 141 ++W+ SR CV H +V FHP + +A +D TV+VWD+ Sbjct: 170 KLWDKTSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHS 229 Query: 142 GALRKKTVSPADDIMRLTQMNTDL--FGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSG 315 A+ + P+ + + ++ L ++ + Y L GH +F T SG Sbjct: 230 AAVNALSFHPSGNYLVTASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFASG 289 Query: 316 ADDRQVKLWRMN 351 D QV +W+ N Sbjct: 290 GSDEQVMVWKSN 301 Score = 55.8 bits (133), Expect = 6e-08 Identities = 49/166 (29%), Positives = 68/166 (40%), Gaps = 15/166 (9%) Frame = +1 Query: 4 IWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD- 180 +W+ + +T GH V C +F P L+ S S D+TVR+W + TV A Sbjct: 45 VWHMKPQTRAYRFAGHKDAVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTA 104 Query: 181 IMRLTQMNTD----LFGGVDAVVK----------YVLEGHDRGVNWASFHPTLPLIVSGA 318 +R +D + D VK + L H V A F P LIVS + Sbjct: 105 TVRSVHFCSDGQSFVTASDDKTVKVWSTHRQKFLFSLSQHINWVRCAKFSPDGRLIVSAS 164 Query: 319 DDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 DD+ VKLW + T V + H V+ V FH I + D Sbjct: 165 DDKTVKLW--DKTSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMD 208 Score = 53.1 bits (126), Expect = 4e-07 Identities = 46/171 (26%), Positives = 77/171 (45%), Gaps = 18/171 (10%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 ++W+ + + L+ H ++V CA F P L+VSAS D+TV++WD R+ S + Sbjct: 128 KVWSTHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWD-KTSRECVHSYCEH 186 Query: 181 IMRLTQMNTDLFG------GVDAVVK------------YVLEGHDRGVNWASFHPTLPLI 306 +T ++ G G+D VK Y L H VN SFHP+ + Sbjct: 187 GGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQL--HSAAVNALSFHPSGNYL 244 Query: 307 VSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSEDK 459 V+ + D +K+ + + + + TL GH + V F + S D+ Sbjct: 245 VTASSDSTLKILDLMEGRL--LYTLHGHQGPATTVAFSRTGEYFASGGSDE 293 Score = 36.2 bits (82), Expect = 0.047 Identities = 32/138 (23%), Positives = 47/138 (34%) Frame = +1 Query: 46 GHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDIMRLTQMNTDLFGGV 225 GH V F + S S+D + VW + + Sbjct: 17 GHRDAVTSVDFSLNTKQLASGSMDSCLMVWHMKPQTR----------------------- 53 Query: 226 DAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVS 405 Y GH V +F P+ L+ SG+ D+ V++W N E R H V Sbjct: 54 ----AYRFAGHKDAVTCVNFSPSGHLLASGSRDKTVRIWVPN--VKGESTVFRAHTATVR 107 Query: 406 CVMFHAKQDIIVSNSEDK 459 V F + V+ S+DK Sbjct: 108 SVHFCSDGQSFVTASDDK 125 Score = 35.0 bits (79), Expect = 0.10 Identities = 22/78 (28%), Positives = 34/78 (43%), Gaps = 1/78 (1%) Frame = +1 Query: 250 EGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMN-DTKAWEVDTLRGHMNNVSCVMFHAK 426 +GH V F + SG+ D + +W M T+A+ GH + V+CV F Sbjct: 16 KGHRDAVTSVDFSLNTKQLASGSMDSCLMVWHMKPQTRAYR---FAGHKDAVTCVNFSPS 72 Query: 427 QDIIVSNSEDKAFASGMP 480 ++ S S DK +P Sbjct: 73 GHLLASGSRDKTVRIWVP 90
>PRP46_YARLI (Q6C709) Pre-mRNA-splicing factor PRP46 (Pre-mRNA-processing| protein 46) Length = 472 Score = 56.6 bits (135), Expect = 3e-08 Identities = 38/140 (27%), Positives = 57/140 (40%) Frame = +1 Query: 37 VLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDIMRLTQMNTDLF 216 V+TGH +V P+ + S D+T+++WD+ A +RLT Sbjct: 158 VITGHQGWVRSVCVEPENQWFATGSADKTIKIWDL----------ATGKLRLT------- 200 Query: 217 GGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVDTLRGHMN 396 L GH GV P P + SG +D+ VK W + K V GH++ Sbjct: 201 ----------LTGHIMGVRALGVSPRHPYMFSGGEDKMVKCWDLETNKV--VRHYHGHLS 248 Query: 397 NVSCVMFHAKQDIIVSNSED 456 V + H D++VS D Sbjct: 249 AVYSLDIHPTLDVLVSAGRD 268 Score = 51.2 bits (121), Expect = 1e-06 Identities = 36/143 (25%), Positives = 56/143 (39%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 + W+ ++ V GH V HP D++VSA D RVWDI +T P Sbjct: 230 KCWDLETNKVVRHYHGHLSAVYSLDIHPTLDVLVSAGRDAVARVWDI-----RTRDPV-- 282 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTK 360 VL GH +N F + P +++ + D V+LW + K Sbjct: 283 --------------------VVLSGHKSTINRVKFQASEPQVITASADETVRLWNLQAGK 322 Query: 361 AWEVDTLRGHMNNVSCVMFHAKQ 429 + TL H +V + H ++ Sbjct: 323 T--MTTLTHHKKSVRGLTLHPEE 343
>TUP1_YEAST (P16649) Glucose repression regulatory protein TUP1 (Flocculation| suppressor protein) (Repressor AER2) Length = 713 Score = 56.6 bits (135), Expect = 3e-08 Identities = 51/185 (27%), Positives = 80/185 (43%), Gaps = 32/185 (17%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALR-KKTVSPAD 177 RIW+ ++R V +L GH + + P D +VS S D+TVR+WD+ + T+S D Sbjct: 468 RIWDIENRKIVMILQGHEQDIYSLDYFPSGDKLVSGSGDRTVRIWDLRTGQCSLTLSIED 527 Query: 178 DIMRLTQMNTD----LFGGVDAVVK-------YVLE----------GHDRGVNWASFHPT 294 + + D G +D V+ +++E GH V F Sbjct: 528 GVTTVAVSPGDGKYIAAGSLDRAVRVWDSETGFLVERLDSENESGTGHKDSVYSVVFTRD 587 Query: 295 LPLIVSGADDRQVKLWRM------NDTKAWEVDTLR----GHMNNVSCVMFHAKQDIIVS 444 +VSG+ DR VKLW + +D+K T GH + V V + I+S Sbjct: 588 GQSVVSGSLDRSVKLWNLQNANNKSDSKTPNSGTCEVTYIGHKDFVLSVATTQNDEYILS 647 Query: 445 NSEDK 459 S+D+ Sbjct: 648 GSKDR 652 Score = 33.9 bits (76), Expect = 0.23 Identities = 17/59 (28%), Positives = 32/59 (54%) Frame = +1 Query: 283 FHPTLPLIVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSEDK 459 F P + +GA+DR +++W + + K V L+GH ++ + + D +VS S D+ Sbjct: 451 FSPDGKFLATGAEDRLIRIWDIENRKI--VMILQGHEQDIYSLDYFPSGDKLVSGSGDR 507 Score = 32.0 bits (71), Expect = 0.88 Identities = 27/133 (20%), Positives = 49/133 (36%), Gaps = 18/133 (13%) Frame = +1 Query: 1 RIWNWQ------------SRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIG 144 ++WN Q S TC GH +V+ + ++ ++S S D+ V WD Sbjct: 601 KLWNLQNANNKSDSKTPNSGTCEVTYIGHKDFVLSVATTQNDEYILSGSKDRGVLFWD-- 658 Query: 145 ALRKKTVSPADDIMRLTQMNTDLFGGVDAVVKYVLEGHDRGV------NWASFHPTLPLI 306 KK+ +P +L+GH V N + P + Sbjct: 659 ---KKSGNPL----------------------LMLQGHRNSVISVAVANGSPLGPEYNVF 693 Query: 307 VSGADDRQVKLWR 345 +G+ D + ++W+ Sbjct: 694 ATGSGDCKARIWK 706
>YQF1_SCHPO (O94394) Hypothetical WD-repeat protein C126.01c in chromosome III| Length = 369 Score = 56.6 bits (135), Expect = 3e-08 Identities = 33/139 (23%), Positives = 55/139 (39%), Gaps = 2/139 (1%) Frame = +1 Query: 7 WNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDIM 186 WN + CV L GH YV C +E L++S S D ++ VWD+ + + + Sbjct: 117 WNVSTGECVETLIGHTDYVKCLLLLEEEGLLLSGSTDASLIVWDVSSQPSRLL------- 169 Query: 187 RLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDT--K 360 Y L GH RG+ + P + + + ++ W + Sbjct: 170 ------------------YKLTGHSRGIECITRQPNTDIFWTCGSESSIRCWHITKVGGS 211 Query: 361 AWEVDTLRGHMNNVSCVMF 417 E + GH +NV C++F Sbjct: 212 QLEEEGFWGHQSNVYCLLF 230 Score = 33.5 bits (75), Expect = 0.30 Identities = 15/47 (31%), Positives = 26/47 (55%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI 141 R+W+ + + +GH Y + ++S+SLDQT+RVWD+ Sbjct: 289 RVWDTTTGNVKDIYSGH--YESVTKILQWKSYLISSSLDQTIRVWDL 333 Score = 32.3 bits (72), Expect = 0.67 Identities = 15/51 (29%), Positives = 30/51 (58%) Frame = +1 Query: 304 IVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 I +G+ D +K W ++ + V+TL GH + V C++ ++ +++S S D Sbjct: 105 IYTGSWDHTIKKWNVSTGEC--VETLIGHTDYVKCLLLLEEEGLLLSGSTD 153
>FBXW7_DROME (Q9VZF4) F-box/WD-repeat protein 7 (F-box and WD-40 domain protein 7)| (Protein archipelago) Length = 1326 Score = 55.8 bits (133), Expect = 6e-08 Identities = 47/152 (30%), Positives = 60/152 (39%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 ++W+ S CV L GH V C H + VVS S D T+RVWDI Sbjct: 1058 KVWDMDSGACVHTLQGHTSTVRCMHLHGSK--VVSGSRDATLRVWDI------------- 1102 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTK 360 +VL GH V + LIVSGA D VK+W + Sbjct: 1103 --------------EQGSCLHVLVGHLAAVRCVQYDG--KLIVSGAYDYMVKIWHPERQE 1146 Query: 361 AWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 + TL+GH N V + F +VS S D Sbjct: 1147 C--LHTLQGHTNRVYSLQFDGLH--VVSGSLD 1174 Score = 42.7 bits (99), Expect = 5e-04 Identities = 40/131 (30%), Positives = 57/131 (43%), Gaps = 17/131 (12%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALR-KKTVSPAD 177 +IW+ + + C+ L GH + V F VVS SLD ++RVWD+ K T+ Sbjct: 1138 KIWHPERQECLHTLQGHTNRVYSLQFDGLH--VVSGSLDTSIRVWDVETGNCKHTLMGHQ 1195 Query: 178 DI---MRLTQMNTDLFGGVDAVVKY----------VLEG---HDRGVNWASFHPTLPLIV 309 + M L Q N + G D+ VK L G H V F+ +V Sbjct: 1196 SLTSGMELRQ-NILVSGNADSTVKVWDITTGQCLQTLSGPNKHHSAVTCLQFNSRF--VV 1252 Query: 310 SGADDRQVKLW 342 + +DD VKLW Sbjct: 1253 TSSDDGTVKLW 1263 Score = 29.6 bits (65), Expect = 4.4 Identities = 25/72 (34%), Positives = 35/72 (48%) Frame = +1 Query: 244 VLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHA 423 VL+GHD V + IVSG+DD +K+W + K + TL GH V Sbjct: 989 VLKGHDDHVI-TCLQFSGNRIVSGSDDNTLKVWSAVNGKC--LRTLVGHTGGVWSSQMSG 1045 Query: 424 KQDIIVSNSEDK 459 +II+S S D+ Sbjct: 1046 --NIIISGSTDR 1055
>PF20_CHLRE (P93107) Flagellar WD-repeat protein PF20| Length = 606 Score = 55.8 bits (133), Expect = 6e-08 Identities = 38/153 (24%), Positives = 61/153 (39%), Gaps = 1/153 (0%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 +IW+++ + CV T H + FH ++V S SLD TVR+WD+ A Sbjct: 393 KIWDFEKQRCVTTFTDHKQAIWSVRFHHLGEVVASGSLDHTVRLWDLPA----------- 441 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTK 360 + L GH VN ++ P + + + D+ V +W D + Sbjct: 442 ----------------GKCRMALRGHVDSVNDLAWQPFSSSLATASSDKTVSVW---DAR 482 Query: 361 AWE-VDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 A T GH N+ + V F+ + S D Sbjct: 483 AGLCTQTYYGHQNSCNGVSFNILGTQLASTDAD 515 Score = 47.8 bits (112), Expect = 2e-05 Identities = 35/137 (25%), Positives = 55/137 (40%) Frame = +1 Query: 46 GHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDIMRLTQMNTDLFGGV 225 GH V + HP + ++V+AS D+T ++W + P D++ + + D GV Sbjct: 324 GHLLSVANLALHPTKPILVTASDDKTWKMWHM---------PGGDLIMCGEGHKDWVAGV 374 Query: 226 DAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVS 405 D FHP + SG D VK+W + V T H + Sbjct: 375 D------------------FHPAGTCLASGGGDSAVKIWDFEKQRC--VTTFTDHKQAIW 414 Query: 406 CVMFHAKQDIIVSNSED 456 V FH +++ S S D Sbjct: 415 SVRFHHLGEVVASGSLD 431 Score = 41.2 bits (95), Expect = 0.001 Identities = 32/153 (20%), Positives = 55/153 (35%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 ++W+ + GH +V FHP + S D V++WD R T Sbjct: 351 KMWHMPGGDLIMCGEGHKDWVAGVDFHPAGTCLASGGGDSAVKIWDFEKQRCVT------ 404 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTK 360 H + + FH ++ SG+ D V+LW + K Sbjct: 405 ---------------------TFTDHKQAIWSVRFHHLGEVVASGSLDHTVRLWDLPAGK 443 Query: 361 AWEVDTLRGHMNNVSCVMFHAKQDIIVSNSEDK 459 LRGH+++V+ + + + + S DK Sbjct: 444 CRM--ALRGHVDSVNDLAWQPFSSSLATASSDK 474 Score = 37.4 bits (85), Expect = 0.021 Identities = 22/71 (30%), Positives = 34/71 (47%) Frame = +1 Query: 250 EGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQ 429 +GH V + HPT P++V+ +DD+ K+W M + GH + V+ V FH Sbjct: 323 KGHLLSVANLALHPTKPILVTASDDKTWKMWHMPGGDL--IMCGEGHKDWVAGVDFHPAG 380 Query: 430 DIIVSNSEDKA 462 + S D A Sbjct: 381 TCLASGGGDSA 391
>RCO1_NEUCR (P78706) Transcriptional repressor rco-1| Length = 604 Score = 55.8 bits (133), Expect = 6e-08 Identities = 45/179 (25%), Positives = 75/179 (41%), Gaps = 26/179 (14%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 R+W+ QSRT GH + F + S S D+TVR+WDI + +V +D Sbjct: 369 RVWDIQSRTIRNTFHGHEQDIYSLDFSRDGRTIASGSGDRTVRLWDIETGQNTSVLSIED 428 Query: 181 IMRLTQMNTD----LFGGVDAVVK------YVLE------GHDRGVNWASFHPTLPLIVS 312 + ++ D G +D V+ Y+ E GH V +F P +VS Sbjct: 429 GVTTVAISPDKQFVAAGSLDKSVRVWDMRGYLAERLEGPDGHKDSVYSVAFSPDGRNLVS 488 Query: 313 GADDRQVKLWRMNDTKAWE----------VDTLRGHMNNVSCVMFHAKQDIIVSNSEDK 459 G+ D+ +K+W ++ + + T GH + V V ++S S+D+ Sbjct: 489 GSLDKTIKMWELSAPRGIPSSAPPKGGRCIKTFEGHRDFVLSVALTPDSQWVLSGSKDR 547 Score = 42.0 bits (97), Expect = 9e-04 Identities = 42/155 (27%), Positives = 64/155 (41%), Gaps = 15/155 (9%) Frame = +1 Query: 40 LTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGA--LRKKTVSPADDIMRL---TQMN 204 LTG + Y+ F P + + + D+ +RVWDI + +R DI L Sbjct: 341 LTG-DLYIRSVCFSPDGKYLATGAEDKLIRVWDIQSRTIRNTFHGHEQDIYSLDFSRDGR 399 Query: 205 TDLFGGVDAVVKY----------VLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMND 354 T G D V+ VL D GV + P + +G+ D+ V++W M Sbjct: 400 TIASGSGDRTVRLWDIETGQNTSVLSIED-GVTTVAISPDKQFVAAGSLDKSVRVWDMRG 458 Query: 355 TKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSEDK 459 A ++ GH ++V V F +VS S DK Sbjct: 459 YLAERLEGPDGHKDSVYSVAFSPDGRNLVSGSLDK 493 Score = 41.2 bits (95), Expect = 0.001 Identities = 35/124 (28%), Positives = 52/124 (41%), Gaps = 2/124 (1%) Frame = +1 Query: 46 GHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDIMRLTQMNTDLFGGV 225 GH V +F P +VS SLD+T+++W++ A R S R + Sbjct: 469 GHKDSVYSVAFSPDGRNLVSGSLDKTIKMWELSAPRGIPSSAPPKGGRCIK--------- 519 Query: 226 DAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLW--RMNDTKAWEVDTLRGHMNN 399 EGH V + P ++SG+ DR V+ W R T+ L+GH N+ Sbjct: 520 ------TFEGHRDFVLSVALTPDSQWVLSGSKDRGVQFWDPRTGHTQL----MLQGHKNS 569 Query: 400 VSCV 411 V V Sbjct: 570 VISV 573 Score = 32.0 bits (71), Expect = 0.88 Identities = 12/37 (32%), Positives = 19/37 (51%) Frame = +1 Query: 28 CVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWD 138 C+ GH +V+ + P V+S S D+ V+ WD Sbjct: 517 CIKTFEGHRDFVLSVALTPDSQWVLSGSKDRGVQFWD 553
>WD51A_MOUSE (Q8JZX3) WD-repeat protein 51A| Length = 405 Score = 55.8 bits (133), Expect = 6e-08 Identities = 49/166 (29%), Positives = 69/166 (41%), Gaps = 15/166 (9%) Frame = +1 Query: 4 IWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD- 180 IW+ + ++ TGH V C +F P L+ S S D+TVR+W + TV A Sbjct: 45 IWHMKPQSRAYRFTGHKDAVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTA 104 Query: 181 IMRLTQMNTD----LFGGVDAVVK----------YVLEGHDRGVNWASFHPTLPLIVSGA 318 +R +D + D VK + L H V A F P LIVS + Sbjct: 105 TVRSVHFCSDGQSLVTASDDKTVKVWSTHRQRFLFSLTQHINWVRCAKFSPDGRLIVSAS 164 Query: 319 DDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 DD+ VKLW + T + + H V+ V FH I + D Sbjct: 165 DDKTVKLW--DKTSRECIHSYCEHGGFVTYVDFHPSGTCIAAAGMD 208 Score = 54.7 bits (130), Expect = 1e-07 Identities = 32/132 (24%), Positives = 54/132 (40%), Gaps = 15/132 (11%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI------------- 141 ++W+ SR C+ H +V FHP + +A +D TV+VWD Sbjct: 170 KLWDKTSRECIHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDARTHRLLQHYQLHS 229 Query: 142 GALRKKTVSPADDIMRLTQMNTDL--FGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSG 315 A+ + P+ + + ++ L ++ + Y L GH +F T SG Sbjct: 230 AAVNALSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFASG 289 Query: 316 ADDRQVKLWRMN 351 D QV +W+ N Sbjct: 290 GSDEQVMVWKSN 301 Score = 53.9 bits (128), Expect = 2e-07 Identities = 46/171 (26%), Positives = 77/171 (45%), Gaps = 18/171 (10%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 ++W+ + + LT H ++V CA F P L+VSAS D+TV++WD R+ S + Sbjct: 128 KVWSTHRQRFLFSLTQHINWVRCAKFSPDGRLIVSASDDKTVKLWD-KTSRECIHSYCEH 186 Query: 181 IMRLTQMNTDLFG------GVDAVVK------------YVLEGHDRGVNWASFHPTLPLI 306 +T ++ G G+D VK Y L H VN SFHP+ + Sbjct: 187 GGFVTYVDFHPSGTCIAAAGMDNTVKVWDARTHRLLQHYQL--HSAAVNALSFHPSGNYL 244 Query: 307 VSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSEDK 459 ++ + D +K+ + + + + TL GH + V F + S D+ Sbjct: 245 ITASSDSTLKILDLMEGRL--LYTLHGHQGPATTVAFSRTGEYFASGGSDE 293 Score = 43.5 bits (101), Expect = 3e-04 Identities = 35/138 (25%), Positives = 51/138 (36%) Frame = +1 Query: 46 GHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDIMRLTQMNTDLFGGV 225 GH V C F + S S+D T+ +W + P R T Sbjct: 17 GHRDAVTCVDFSLNTKHLASGSMDSTLMIWH--------MKPQSRAYRFT---------- 58 Query: 226 DAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVS 405 GH V +F P+ L+ SG+ D+ V++W N E R H V Sbjct: 59 ---------GHKDAVTCVNFSPSGHLLASGSRDKTVRIWVPN--VKGESTVFRAHTATVR 107 Query: 406 CVMFHAKQDIIVSNSEDK 459 V F + +V+ S+DK Sbjct: 108 SVHFCSDGQSLVTASDDK 125 Score = 34.7 bits (78), Expect = 0.14 Identities = 21/78 (26%), Positives = 34/78 (43%), Gaps = 1/78 (1%) Frame = +1 Query: 250 EGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMN-DTKAWEVDTLRGHMNNVSCVMFHAK 426 +GH V F + SG+ D + +W M ++A+ GH + V+CV F Sbjct: 16 KGHRDAVTCVDFSLNTKHLASGSMDSTLMIWHMKPQSRAYR---FTGHKDAVTCVNFSPS 72 Query: 427 QDIIVSNSEDKAFASGMP 480 ++ S S DK +P Sbjct: 73 GHLLASGSRDKTVRIWVP 90
>TUP11_SCHPO (Q09715) Transcriptional repressor tup11| Length = 614 Score = 55.5 bits (132), Expect = 7e-08 Identities = 41/152 (26%), Positives = 66/152 (43%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 R+W+ S T V L GH V +F P +++S SLD+T++VW++ A R +S Sbjct: 468 RVWS-VSGTLVERLEGHKESVYSIAFSPDSSILLSGSLDKTIKVWELQATRSVGLSAIKP 526 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTK 360 + + K GH V + P +SG+ DR ++ W + + Sbjct: 527 ---------------EGICKATYTGHTDFVLSVAVSPDSRWGLSGSKDRSMQFWDLQTGQ 571 Query: 361 AWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 ++ T +GH N+V V F S S D Sbjct: 572 SYL--TCQGHKNSVISVCFSPDGRQFASGSGD 601 Score = 52.0 bits (123), Expect = 8e-07 Identities = 30/134 (22%), Positives = 60/134 (44%), Gaps = 13/134 (9%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI------------G 144 ++W+ ++ V +GH + F +VS S D+T R+WD+ Sbjct: 385 KLWDLSTQKVRYVFSGHEQDIYSLDFSHNGRFIVSGSGDRTARLWDVETGQCILKLEIEN 444 Query: 145 ALRKKTVSPADDIMRLTQMNTDL-FGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGAD 321 + +SP D + + ++ + V + LEGH V +F P +++SG+ Sbjct: 445 GVTAIAISPNDQFIAVGSLDQIIRVWSVSGTLVERLEGHKESVYSIAFSPDSSILLSGSL 504 Query: 322 DRQVKLWRMNDTKA 363 D+ +K+W + T++ Sbjct: 505 DKTIKVWELQATRS 518 Score = 41.2 bits (95), Expect = 0.001 Identities = 36/148 (24%), Positives = 63/148 (42%), Gaps = 14/148 (9%) Frame = +1 Query: 58 YVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTV--SPADDIMRLTQMNTDLF---GG 222 YV +F P +V+ + D+ +++WD+ + + V DI L + F G Sbjct: 362 YVRTIAFSPDGKYLVTGTEDRQIKLWDLSTQKVRYVFSGHEQDIYSLDFSHNGRFIVSGS 421 Query: 223 VDAVVKY--VLEGH-------DRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVD 375 D + V G + GV + P I G+ D+ +++W ++ T V+ Sbjct: 422 GDRTARLWDVETGQCILKLEIENGVTAIAISPNDQFIAVGSLDQIIRVWSVSGTL---VE 478 Query: 376 TLRGHMNNVSCVMFHAKQDIIVSNSEDK 459 L GH +V + F I++S S DK Sbjct: 479 RLEGHKESVYSIAFSPDSSILLSGSLDK 506 Score = 36.6 bits (83), Expect = 0.036 Identities = 22/67 (32%), Positives = 33/67 (49%) Frame = +1 Query: 259 DRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDII 438 D V +F P +V+G +DRQ+KLW ++ K V GH ++ + F I Sbjct: 360 DLYVRTIAFSPDGKYLVTGTEDRQIKLWDLSTQKVRYV--FSGHEQDIYSLDFSHNGRFI 417 Query: 439 VSNSEDK 459 VS S D+ Sbjct: 418 VSGSGDR 424
>TAF5_HUMAN (Q15542) Transcription initiation factor TFIID subunit 5| (Transcription initiation factor TFIID 100 kDa subunit) (TAF(II)100) (TAFII-100) (TAFII100) Length = 800 Score = 55.1 bits (131), Expect = 1e-07 Identities = 37/152 (24%), Positives = 60/152 (39%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 R+W + + GH V C FHP + V + S D+TVR+WD+ Sbjct: 610 RLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDV------------- 656 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTK 360 ++ + GH ++ +F P + +GA D +V LW + Sbjct: 657 --------------LNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIG--H 700 Query: 361 AWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 V L+GH + V + F +I+ S S D Sbjct: 701 GLMVGELKGHTDTVCSLRFSRDGEILASGSMD 732 Score = 53.9 bits (128), Expect = 2e-07 Identities = 41/153 (26%), Positives = 67/153 (43%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 RI + ++ + + +L GH+ V ASF P + ++S+S D TVR+W + Sbjct: 526 RIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSL------------- 572 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTK 360 Q T L G +GH+ V F P VSG DR +LW + + Sbjct: 573 -----QTFTCLVG---------YKGHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQ 618 Query: 361 AWEVDTLRGHMNNVSCVMFHAKQDIIVSNSEDK 459 + GH+ +V+C FH + + + S D+ Sbjct: 619 PLRI--FAGHLADVNCTRFHPNSNYVATGSADR 649
>SEL10_CAEEL (Q93794) F-box/WD-repeat protein sel-10 (Suppressor/enhancer of| lin-12) (Sel-10 protein) Length = 587 Score = 55.1 bits (131), Expect = 1e-07 Identities = 39/152 (25%), Positives = 71/152 (46%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 +IWN + C+ LTGHN+ V F + +V S SLD ++RVWD T + Sbjct: 401 KIWNAHTGRCIRTLTGHNNRVYSLLFESERSIVCSGSLDTSIRVWDF------TRPEGQE 454 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTK 360 + L Q +T L G+ L G+ ++VS D V++W +++ Sbjct: 455 CVALLQGHTSLTSGMQ------LRGN--------------ILVSCNADSHVRVWDIHEGT 494 Query: 361 AWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 V L GH + ++ + + + +++ ++S+D Sbjct: 495 C--VHMLSGHRSAITSLQWFGR-NMVATSSDD 523 Score = 49.7 bits (117), Expect = 4e-06 Identities = 42/165 (25%), Positives = 66/165 (40%), Gaps = 13/165 (7%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWD-IGALRKKTVSPAD 177 ++W + L GH V + +VS S D+TV+VW + T+ Sbjct: 279 KVWCIDKGEVMYTLVGHTGGVWTSQISQCGRYIVSGSTDRTVKVWSTVDGSLLHTLQGHT 338 Query: 178 DIMRLTQMNTDLF--GGVDAVVKY----------VLEGHDRGVNWASFHPTLPLIVSGAD 321 +R M + G D ++ L GH V F T +VSG Sbjct: 339 STVRCMAMAGSILVTGSRDTTLRVWDVESGRHLATLHGHHAAVRCVQFDGT--TVVSGGY 396 Query: 322 DRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 D VK+W + + + TL GH N V ++F +++ I+ S S D Sbjct: 397 DFTVKIWNAHTGRC--IRTLTGHNNRVYSLLFESERSIVCSGSLD 439 Score = 29.3 bits (64), Expect = 5.7 Identities = 23/73 (31%), Positives = 34/73 (46%), Gaps = 1/73 (1%) Frame = +1 Query: 244 VLEGH-DRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFH 420 VL GH D + H + +V+G+DD +K+W ++ K + TL GH V Sbjct: 250 VLRGHEDHVITCMQIHDDV--LVTGSDDNTLKVWCID--KGEVMYTLVGHTGGVWTSQIS 305 Query: 421 AKQDIIVSNSEDK 459 IVS S D+ Sbjct: 306 QCGRYIVSGSTDR 318
>TAF5_DROME (P49846) Transcription initiation factor TFIID subunit 5| (Transcription initiation factor TFIID 85 kDa subunit) (p85) (TAFII-80) Length = 704 Score = 54.7 bits (130), Expect = 1e-07 Identities = 42/152 (27%), Positives = 60/152 (39%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 R+W+ + +CV GH + V F P VS S D+T R+W Sbjct: 475 RLWSLLTWSCVVTYRGHVYPVWDVRFAPHGYYFVSCSYDKTARLW--------------- 519 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTK 360 T N L V GH V+ FHP + +G+ DR V+LW ++ Sbjct: 520 ---ATDSNQAL---------RVFVGHLSDVDCVQFHPNSNYVATGSSDRTVRLW--DNMT 565 Query: 361 AWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 V + GH +VS + F A + S S D Sbjct: 566 GQSVRLMTGHKGSVSSLAFSACGRYLASGSVD 597 Score = 50.8 bits (120), Expect = 2e-06 Identities = 41/146 (28%), Positives = 62/146 (42%), Gaps = 5/146 (3%) Frame = +1 Query: 37 VLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDIMRL----TQMN 204 VL H V CA ++ D +VR+W + + +T+ AD + L +N Sbjct: 373 VLNSHQG-VTCAEISDDSTMLACGFGDSSVRIWSLTPAKLRTLKDADSLRELDKESADIN 431 Query: 205 TDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWE-VDTL 381 + V L GH V +F P + L++S ++D ++LW + W V T Sbjct: 432 VRMLDDRSGEVTRSLMGHTGPVYRCAFAPEMNLLLSCSEDSTIRLWSL---LTWSCVVTY 488 Query: 382 RGHMNNVSCVMFHAKQDIIVSNSEDK 459 RGH+ V V F VS S DK Sbjct: 489 RGHVYPVWDVRFAPHGYYFVSCSYDK 514 Score = 50.1 bits (118), Expect = 3e-06 Identities = 36/152 (23%), Positives = 60/152 (39%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 R+W S + V GH V C FHP + V + S D+TVR+WD Sbjct: 517 RLWATDSNQALRVFVGHLSDVDCVQFHPNSNYVATGSSDRTVRLWD-------------- 562 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTK 360 +T + L + GH V+ +F + SG+ D + +W +++ Sbjct: 563 --NMTGQSVRL-----------MTGHKGSVSSLAFSACGRYLASGSVDHNIIIWDLSNGS 609 Query: 361 AWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 V TL H + V+ + F ++ + D Sbjct: 610 L--VTTLLRHTSTVTTITFSRDGTVLAAAGLD 639
>WDR57_PONPY (Q5RF51) WD-repeat protein 57| Length = 357 Score = 54.7 bits (130), Expect = 1e-07 Identities = 39/158 (24%), Positives = 70/158 (44%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 ++W+ + + GH V S + ++S ++D TVRVWD+ + +P + Sbjct: 218 KVWDLRQNKLTYTMRGHADSVTGLSLSSEGSYLLSNAMDNTVRVWDV-----RPFAPKER 272 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTK 360 +++ Q N F ++ + S+ P I +G+ DR V +W + T Sbjct: 273 CVKIFQGNVHNF--------------EKNLLRCSWSPDGSKIAAGSADRSVCVW--DTTS 316 Query: 361 AWEVDTLRGHMNNVSCVMFHAKQDIIVSNSEDKAFASG 474 + L GH +++ V FH + II+S S DK G Sbjct: 317 RRILYKLPGHAGSINEVAFHPDEPIIISASSDKRLYMG 354 Score = 43.5 bits (101), Expect = 3e-04 Identities = 47/200 (23%), Positives = 76/200 (38%), Gaps = 58/200 (29%) Frame = +1 Query: 31 VAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI--GALRKKTVSPADDIMRLTQMN 204 + +L+GH V C FHP + SA D+ + +W++ T+ + N Sbjct: 59 IMLLSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCGNYATLKGYSGAVMELHYN 118 Query: 205 TD---LF-GGVDAVVKY----------VLEGHDRGVNWASFHPTL---PLIVSGADDRQV 333 TD LF D V L+GH VN S +P L+ +G+DD V Sbjct: 119 TDGSMLFSASTDKTVAVWDSETGERVKRLKGHTSFVN--SCYPARRGPQLVCTGSDDGTV 176 Query: 334 KLWRM---------------------------------NDTKAWEVD------TLRGHMN 396 KLW + ND K W++ T+RGH + Sbjct: 177 KLWDIRKKAAIQTFQNTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHAD 236 Query: 397 NVSCVMFHAKQDIIVSNSED 456 +V+ + ++ ++SN+ D Sbjct: 237 SVTGLSLSSEGSYLLSNAMD 256 Score = 34.3 bits (77), Expect = 0.18 Identities = 15/46 (32%), Positives = 27/46 (58%) Frame = +1 Query: 4 IWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI 141 +W+ SR + L GH + +FHP E +++SAS D+ + + +I Sbjct: 311 VWDTTSRRILYKLPGHAGSINEVAFHPDEPIIISASSDKRLYMGEI 356 Score = 33.9 bits (76), Expect = 0.23 Identities = 21/75 (28%), Positives = 33/75 (44%) Frame = +1 Query: 244 VLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHA 423 +L GH+ V FHP + S DR + LW + TL+G+ V + ++ Sbjct: 61 LLSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYG-DCGNYATLKGYSGAVMELHYNT 119 Query: 424 KQDIIVSNSEDKAFA 468 ++ S S DK A Sbjct: 120 DGSMLFSASTDKTVA 134
>POP2_SCHPO (O14170) WD-repeat protein pop2 (Proteolysis factor sud1)| Length = 703 Score = 54.3 bits (129), Expect = 2e-07 Identities = 42/170 (24%), Positives = 74/170 (43%), Gaps = 16/170 (9%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASF--------------HPKEDLVVSASLDQTVRVWD 138 R+WN + C + GH + C P + +VS S D T+RVW Sbjct: 414 RVWNIEKAKCTHIFRGHISIIRCLEILVPSRLIRHGVEIVEPDQPYIVSGSRDHTLRVWK 473 Query: 139 IGALRKKTVSP--ADDIMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVS 312 L K T P D+ + + + + + L GH V S + + +VS Sbjct: 474 ---LPKNTDPPYLPDNTNSIDRWEKNPY------FVHTLIGHTDSVRTISGYGDI--LVS 522 Query: 313 GADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSEDKA 462 G+ D +++WR++ + + LRGH + V++ +++I +S S DK+ Sbjct: 523 GSYDSSIRIWRVSTGEC--LYHLRGHSLRIYSVLYEPERNICISGSMDKS 570 Score = 53.5 bits (127), Expect = 3e-07 Identities = 30/120 (25%), Positives = 52/120 (43%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 RIW + C+ L GH+ + + P+ ++ +S S+D+++RVWD+ Sbjct: 530 RIWRVSTGECLYHLRGHSLRIYSVLYEPERNICISGSMDKSIRVWDLST----------- 578 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTK 360 KYVLEGHD V + ++SG+ D +++W +N K Sbjct: 579 ----------------GTCKYVLEGHDAFVTLLNVFQN--RLISGSADSTIRIWDLNTGK 620 Score = 45.8 bits (107), Expect = 6e-05 Identities = 45/161 (27%), Positives = 70/161 (43%), Gaps = 18/161 (11%) Frame = +1 Query: 34 AVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDIMRLTQMNTDL 213 A L GH V H E+ +VS S+D+TVRVW+I + + + + + Sbjct: 385 ARLEGHKEGVWAVKIH--ENTLVSGSIDKTVRVWNIEKAK---------CTHIFRGHISI 433 Query: 214 FGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRM-------------ND 354 ++ +V L H GV P P IVSG+ D +++W++ N Sbjct: 434 IRCLEILVPSRLIRH--GVE--IVEPDQPYIVSGSRDHTLRVWKLPKNTDPPYLPDNTNS 489 Query: 355 TKAWE-----VDTLRGHMNNVSCVMFHAKQDIIVSNSEDKA 462 WE V TL GH ++V + + DI+VS S D + Sbjct: 490 IDRWEKNPYFVHTLIGHTDSVRTISGYG--DILVSGSYDSS 528 Score = 37.0 bits (84), Expect = 0.027 Identities = 19/67 (28%), Positives = 34/67 (50%) Frame = +1 Query: 211 LFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVDTLRGH 390 + + V++ LEGH GV H +VSG+ D+ V++W + K + RGH Sbjct: 375 IHNAITGVLEARLEGHKEGVWAVKIHENT--LVSGSIDKTVRVWNIEKAKCTHI--FRGH 430 Query: 391 MNNVSCV 411 ++ + C+ Sbjct: 431 ISIIRCL 437
>PRP19_CHICK (Q5ZMA2) Pre-mRNA-splicing factor 19 (PRP19/PSO4 homolog)| Length = 505 Score = 54.3 bits (129), Expect = 2e-07 Identities = 39/171 (22%), Positives = 72/171 (42%), Gaps = 18/171 (10%) Frame = +1 Query: 4 IWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI-------------G 144 +++ S +A L GH+ V FHP +DLV SAS D T+R+W + G Sbjct: 249 VFDKSSEQILATLKGHSKKVTSVVFHPSQDLVFSASPDATIRIWSVPNASCVQVVRAHEG 308 Query: 145 ALRKKTVSPADDIMRLTQMNTDLFGGVD-----AVVKYVLEGHDRGVNWASFHPTLPLIV 309 ++ ++ D + L+ + + D + K E + A FHP + Sbjct: 309 SVTGLSLHATGDYL-LSSSDDQYWAFSDIQTGRVLTKVTDESSGCALTCAQFHPDGLIFG 367 Query: 310 SGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSEDKA 462 +G D Q+K+W + + V GH ++ + F + + ++D + Sbjct: 368 TGTMDSQIKIWDLKERT--NVANFPGHSGPITSIAFSENGYYLATAADDSS 416 Score = 48.1 bits (113), Expect = 1e-05 Identities = 24/89 (26%), Positives = 46/89 (51%) Frame = +1 Query: 202 NTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVDTL 381 N +F + L+GH + V FHP+ L+ S + D +++W + + V + Sbjct: 246 NVIVFDKSSEQILATLKGHSKKVTSVVFHPSQDLVFSASPDATIRIWSVPNASC--VQVV 303 Query: 382 RGHMNNVSCVMFHAKQDIIVSNSEDKAFA 468 R H +V+ + HA D ++S+S+D+ +A Sbjct: 304 RAHEGSVTGLSLHATGDYLLSSSDDQYWA 332 Score = 39.7 bits (91), Expect = 0.004 Identities = 37/137 (27%), Positives = 56/137 (40%), Gaps = 17/137 (12%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGA---LRKKTVSP 171 RIW+ + +CV V+ H V S H D ++S+S DQ DI L K T Sbjct: 290 RIWSVPNASCVQVVRAHEGSVTGLSLHATGDYLLSSSDDQYWAFSDIQTGRVLTKVTDES 349 Query: 172 ADDIMRLTQMNTD--LFGG--VDAVVKYV----------LEGHDRGVNWASFHPTLPLIV 309 + + Q + D +FG +D+ +K GH + +F + Sbjct: 350 SGCALTCAQFHPDGLIFGTGTMDSQIKIWDLKERTNVANFPGHSGPITSIAFSENGYYLA 409 Query: 310 SGADDRQVKLWRMNDTK 360 + ADD VKLW + K Sbjct: 410 TAADDSSVKLWDLRKLK 426 Score = 34.3 bits (77), Expect = 0.18 Identities = 18/73 (24%), Positives = 35/73 (47%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 +IW+ + RT VA GH+ + +F + +A+ D +V++WD+ L+ D+ Sbjct: 376 KIWDLKERTNVANFPGHSGPITSIAFSENGYYLATAADDSSVKLWDLRKLKNFKTLQLDN 435 Query: 181 IMRLTQMNTDLFG 219 + + D G Sbjct: 436 NFEVKSLIFDQSG 448
>GBLP_TRYBR (P69104) Guanine nucleotide-binding protein beta subunit-like| protein (Activated protein kinase C receptor homolog) (Track) Length = 318 Score = 54.3 bits (129), Expect = 2e-07 Identities = 41/154 (26%), Positives = 61/154 (39%), Gaps = 2/154 (1%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 R+WN Q+ C GH V+ +F P +VS D +RVW++ T+S Sbjct: 92 RLWNLQNGQCQYKFLGHTKDVLSVAFSPDNRQIVSGGRDNALRVWNVKGECMHTLSRG-- 149 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTL--PLIVSGADDRQVKLWRMND 354 H V+ F P+L P+IVSG D VK+W + Sbjct: 150 ------------------------AHTDWVSCVRFSPSLDAPVIVSGGWDNLVKVWDLAT 185 Query: 355 TKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 + V L+GH N V+ V + S+ +D Sbjct: 186 GRL--VTDLKGHTNYVTSVTVSPDGSLCASSDKD 217
>GBLP_TRYBB (P69103) Guanine nucleotide-binding protein beta subunit-like| protein (Activated protein kinase C receptor homolog) Length = 318 Score = 54.3 bits (129), Expect = 2e-07 Identities = 41/154 (26%), Positives = 61/154 (39%), Gaps = 2/154 (1%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 R+WN Q+ C GH V+ +F P +VS D +RVW++ T+S Sbjct: 92 RLWNLQNGQCQYKFLGHTKDVLSVAFSPDNRQIVSGGRDNALRVWNVKGECMHTLSRG-- 149 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTL--PLIVSGADDRQVKLWRMND 354 H V+ F P+L P+IVSG D VK+W + Sbjct: 150 ------------------------AHTDWVSCVRFSPSLDAPVIVSGGWDNLVKVWDLAT 185 Query: 355 TKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 + V L+GH N V+ V + S+ +D Sbjct: 186 GRL--VTDLKGHTNYVTSVTVSPDGSLCASSDKD 217
>FBXW7_HUMAN (Q969H0) F-box/WD-repeat protein 7 (F-box and WD-40 domain protein| 7) (F-box protein FBX30) (hCdc4) (Archipelago homolog) (hAgo) (SEL-10) Length = 707 Score = 54.3 bits (129), Expect = 2e-07 Identities = 48/171 (28%), Positives = 73/171 (42%), Gaps = 19/171 (11%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI------------- 141 ++WN ++ C+ L GH V C H K VVS S D T+RVWDI Sbjct: 444 KVWNAETGECIHTLYGHTSTVRCMHLHEKR--VVSGSRDATLRVWDIETGQCLHVLMGHV 501 Query: 142 GALR------KKTVSPADDIMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPL 303 A+R ++ VS A D M ++ + L+GH V F Sbjct: 502 AAVRCVQYDGRRVVSGAYDFM------VKVWDPETETCLHTLQGHTNRVYSLQFDGI--H 553 Query: 304 IVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 +VSG+ D +++W + + TL GH + S + K +I+VS + D Sbjct: 554 VVSGSLDTSIRVWDVETGNC--IHTLTGHQSLTSGM--ELKDNILVSGNAD 600 Score = 45.1 bits (105), Expect = 1e-04 Identities = 41/141 (29%), Positives = 58/141 (41%), Gaps = 1/141 (0%) Frame = +1 Query: 37 VLTGHN-HYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDIMRLTQMNTDL 213 VL GH+ H + C F +VS S D T++VW Sbjct: 375 VLKGHDDHVITCLQFCGNR--IVSGSDDNTLKVWS------------------------- 407 Query: 214 FGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVDTLRGHM 393 V L GH GV W+S +I+SG+ DR +K+W + + TL GH Sbjct: 408 --AVTGKCLRTLVGHTGGV-WSS-QMRDNIIISGSTDRTLKVWNAETGEC--IHTLYGHT 461 Query: 394 NNVSCVMFHAKQDIIVSNSED 456 + V C+ H K+ +VS S D Sbjct: 462 STVRCMHLHEKR--VVSGSRD 480 Score = 43.1 bits (100), Expect = 4e-04 Identities = 34/130 (26%), Positives = 58/130 (44%), Gaps = 16/130 (12%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRK-KTVSPAD 177 ++W+ ++ TC+ L GH + V F VVS SLD ++RVWD+ T++ Sbjct: 524 KVWDPETETCLHTLQGHTNRVYSLQFDGIH--VVSGSLDTSIRVWDVETGNCIHTLTGHQ 581 Query: 178 DIMRLTQMNTDLF--GGVDAVVKY----------VLEG---HDRGVNWASFHPTLPLIVS 312 + ++ ++ G D+ VK L+G H V F+ +++ Sbjct: 582 SLTSGMELKDNILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKNF--VIT 639 Query: 313 GADDRQVKLW 342 +DD VKLW Sbjct: 640 SSDDGTVKLW 649 Score = 42.4 bits (98), Expect = 7e-04 Identities = 44/168 (26%), Positives = 73/168 (43%), Gaps = 16/168 (9%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWD------IGALRKKT 162 ++W+ + C+ L GH V + ++++++S S D+T++VW+ I L T Sbjct: 404 KVWSAVTGKCLRTLVGHTGGVWSSQM--RDNIIISGSTDRTLKVWNAETGECIHTLYGHT 461 Query: 163 VSPADDIMRLTQMNTDLFGGVDAVVK----------YVLEGHDRGVNWASFHPTLPLIVS 312 + M L + + G DA ++ +VL GH V + +VS Sbjct: 462 STVR--CMHLHEKRV-VSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYDGR--RVVS 516 Query: 313 GADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 GA D VK+W + TL+GH N V + F +VS S D Sbjct: 517 GAYDFMVKVWDPETETC--LHTLQGHTNRVYSLQFDGIH--VVSGSLD 560 Score = 29.3 bits (64), Expect = 5.7 Identities = 19/52 (36%), Positives = 27/52 (51%) Frame = +1 Query: 304 IVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSEDK 459 IVSG+DD +K+W K + TL GH V + +II+S S D+ Sbjct: 394 IVSGSDDNTLKVWSAVTGKC--LRTLVGHTGGVWSSQM--RDNIIISGSTDR 441
>FBXW7_MOUSE (Q8VBV4) F-box/WD-repeat protein 7 (F-box and WD-40 domain protein| 7) (F-box protein FBW7) (F-box protein Fbxw6) (F-box-WD40 repeat protein 6) (SEL-10) Length = 629 Score = 54.3 bits (129), Expect = 2e-07 Identities = 48/171 (28%), Positives = 73/171 (42%), Gaps = 19/171 (11%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI------------- 141 ++WN ++ C+ L GH V C H K VVS S D T+RVWDI Sbjct: 366 KVWNAETGECIHTLYGHTSTVRCMHLHEKR--VVSGSRDATLRVWDIETGQCLHVLMGHV 423 Query: 142 GALR------KKTVSPADDIMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPL 303 A+R ++ VS A D M ++ + L+GH V F Sbjct: 424 AAVRCVQYDGRRVVSGAYDFM------VKVWDPETETCLHTLQGHTNRVYSLQFDGI--H 475 Query: 304 IVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 +VSG+ D +++W + + TL GH + S + K +I+VS + D Sbjct: 476 VVSGSLDTSIRVWDVETGNC--IHTLTGHQSLTSGM--ELKDNILVSGNAD 522 Score = 45.1 bits (105), Expect = 1e-04 Identities = 41/141 (29%), Positives = 58/141 (41%), Gaps = 1/141 (0%) Frame = +1 Query: 37 VLTGHN-HYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDIMRLTQMNTDL 213 VL GH+ H + C F +VS S D T++VW Sbjct: 297 VLKGHDDHVITCLQFCGNR--IVSGSDDNTLKVWS------------------------- 329 Query: 214 FGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVDTLRGHM 393 V L GH GV W+S +I+SG+ DR +K+W + + TL GH Sbjct: 330 --AVTGKCLRTLVGHTGGV-WSS-QMRDNIIISGSTDRTLKVWNAETGEC--IHTLYGHT 383 Query: 394 NNVSCVMFHAKQDIIVSNSED 456 + V C+ H K+ +VS S D Sbjct: 384 STVRCMHLHEKR--VVSGSRD 402 Score = 43.1 bits (100), Expect = 4e-04 Identities = 34/130 (26%), Positives = 58/130 (44%), Gaps = 16/130 (12%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRK-KTVSPAD 177 ++W+ ++ TC+ L GH + V F VVS SLD ++RVWD+ T++ Sbjct: 446 KVWDPETETCLHTLQGHTNRVYSLQFDGIH--VVSGSLDTSIRVWDVETGNCIHTLTGHQ 503 Query: 178 DIMRLTQMNTDLF--GGVDAVVKY----------VLEG---HDRGVNWASFHPTLPLIVS 312 + ++ ++ G D+ VK L+G H V F+ +++ Sbjct: 504 SLTSGMELKDNILVSGNADSTVKIWDIKTGQCLQTLQGPSKHQSAVTCLQFNKNF--VIT 561 Query: 313 GADDRQVKLW 342 +DD VKLW Sbjct: 562 SSDDGTVKLW 571 Score = 42.4 bits (98), Expect = 7e-04 Identities = 44/168 (26%), Positives = 73/168 (43%), Gaps = 16/168 (9%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWD------IGALRKKT 162 ++W+ + C+ L GH V + ++++++S S D+T++VW+ I L T Sbjct: 326 KVWSAVTGKCLRTLVGHTGGVWSSQM--RDNIIISGSTDRTLKVWNAETGECIHTLYGHT 383 Query: 163 VSPADDIMRLTQMNTDLFGGVDAVVK----------YVLEGHDRGVNWASFHPTLPLIVS 312 + M L + + G DA ++ +VL GH V + +VS Sbjct: 384 STVR--CMHLHEKRV-VSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYDGR--RVVS 438 Query: 313 GADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 GA D VK+W + TL+GH N V + F +VS S D Sbjct: 439 GAYDFMVKVWDPETETC--LHTLQGHTNRVYSLQFDGIH--VVSGSLD 482 Score = 29.3 bits (64), Expect = 5.7 Identities = 19/52 (36%), Positives = 27/52 (51%) Frame = +1 Query: 304 IVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSEDK 459 IVSG+DD +K+W K + TL GH V + +II+S S D+ Sbjct: 316 IVSGSDDNTLKVWSAVTGKC--LRTLVGHTGGVWSSQM--RDNIIISGSTDR 363
>GBLP_ORYSA (P49027) Guanine nucleotide-binding protein beta subunit-like| protein (GPB-LR) (RWD) Length = 334 Score = 54.3 bits (129), Expect = 2e-07 Identities = 43/154 (27%), Positives = 65/154 (42%), Gaps = 2/154 (1%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 R+W+ + GH+ V+ +F +VSAS D+T+++W+ K T+ Sbjct: 100 RLWDLSTGVTTRRFVGHDKDVLSVAFSVDNRQIVSASRDRTIKLWNTLGECKYTI----- 154 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTL--PLIVSGADDRQVKLWRMND 354 DL GG EGH+ V+ F P P IVSG+ DR VK+W + + Sbjct: 155 -------GGDLGGG---------EGHNGWVSCVRFSPNTFQPTIVSGSWDRTVKVWNLTN 198 Query: 355 TKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 K L GH V+ V + S +D Sbjct: 199 CKL--RCNLEGHGGYVNAVAVSPDGSLCASGGKD 230 Score = 40.0 bits (92), Expect = 0.003 Identities = 29/107 (27%), Positives = 42/107 (39%), Gaps = 2/107 (1%) Frame = +1 Query: 46 GHNHYVMCASFHPK--EDLVVSASLDQTVRVWDIGALRKKTVSPADDIMRLTQMNTDLFG 219 GHN +V C F P + +VS S D+TV+VW++ Sbjct: 163 GHNGWVSCVRFSPNTFQPTIVSGSWDRTVKVWNL-------------------------- 196 Query: 220 GVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTK 360 + ++ LEGH VN + P L SG D LW + + K Sbjct: 197 -TNCKLRCNLEGHGGYVNAVAVSPDGSLCASGGKDGVTLLWDLAEGK 242 Score = 28.9 bits (63), Expect = 7.5 Identities = 13/47 (27%), Positives = 19/47 (40%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI 141 ++WN + L GH YV + P L S D +WD+ Sbjct: 192 KVWNLTNCKLRCNLEGHGGYVNAVAVSPDGSLCASGGKDGVTLLWDL 238
>PWP2_NEUCR (Q9C270) Periodic tryptophan protein 2 homolog| Length = 899 Score = 54.3 bits (129), Expect = 2e-07 Identities = 33/131 (25%), Positives = 60/131 (45%), Gaps = 17/131 (12%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 ++W+ +S C+ T H + F K +++ ++SLD ++R WD+ R A + Sbjct: 364 KVWDTESGFCIVTFTEHTSGITACEFSKKGNVLFTSSLDGSIRAWDLIRYRNFRTFTAPE 423 Query: 181 IMRLTQMNTD------LFGGVDAVVKYV-----------LEGHDRGVNWASFHPTLPLIV 309 + + M D G VD+ ++ L GH+ V+ +F P L+V Sbjct: 424 RLSFSCMAVDPSGEIVAAGSVDSFDIHIWSVQTGQLLDRLSGHEGPVSSLAFAPNGGLLV 483 Query: 310 SGADDRQVKLW 342 SG+ DR ++W Sbjct: 484 SGSWDRTARIW 494 Score = 37.4 bits (85), Expect = 0.021 Identities = 18/46 (39%), Positives = 26/46 (56%) Frame = +1 Query: 4 IWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI 141 IW+ Q+ + L+GH V +F P L+VS S D+T R+W I Sbjct: 451 IWSVQTGQLLDRLSGHEGPVSSLAFAPNGGLLVSGSWDRTARIWSI 496 Score = 37.4 bits (85), Expect = 0.021 Identities = 34/149 (22%), Positives = 71/149 (47%), Gaps = 17/149 (11%) Frame = +1 Query: 61 VMCASFHPKEDLVVSASLDQTVRVW---DIGALRKKTVSPAD-DIMRLTQMNTDLFGGVD 228 V CA+FHP+ +L+V+ + ++ D + ++S + D + + + L G Sbjct: 257 VRCAAFHPESNLLVAGFSNGIFGLYEMPDFNMIHTLSISQNEIDFVTINKSGEWLAFGAS 316 Query: 229 AVVK----------YVL--EGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKA-WE 369 + + Y+L +GH +N + P IV+ ADD ++K+W DT++ + Sbjct: 317 KLGQLLVWEWQSESYILKQQGHFDSMNSLVYSPDGQRIVTVADDGKIKVW---DTESGFC 373 Query: 370 VDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 + T H + ++ F K +++ ++S D Sbjct: 374 IVTFTEHTSGITACEFSKKGNVLFTSSLD 402
>TAF5_MOUSE (Q8C092) Transcription initiation factor TFIID subunit 5| (Transcription initiation factor TFIID 100 kDa subunit) (TAF(II)100) (TAFII-100) (TAFII100) Length = 801 Score = 53.9 bits (128), Expect = 2e-07 Identities = 36/152 (23%), Positives = 60/152 (39%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 R+W + + GH V C +HP + V + S D+TVR+WD+ Sbjct: 611 RLWATDHYQPLRIFAGHLADVNCTRYHPNSNYVATGSADRTVRLWDV------------- 657 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTK 360 ++ + GH ++ +F P + +GA D +V LW + Sbjct: 658 --------------LNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIG--H 701 Query: 361 AWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 V L+GH + V + F +I+ S S D Sbjct: 702 GLMVGELKGHTDTVCSLRFSRDGEILASGSMD 733 Score = 52.8 bits (125), Expect = 5e-07 Identities = 40/153 (26%), Positives = 67/153 (43%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 RI + ++ + + +L GH+ V ASF P + ++S+S D TVR+W + Sbjct: 527 RIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSL------------- 573 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTK 360 Q T L G +GH+ V F P VSG DR +LW + + Sbjct: 574 -----QTFTCLVG---------YKGHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQ 619 Query: 361 AWEVDTLRGHMNNVSCVMFHAKQDIIVSNSEDK 459 + GH+ +V+C +H + + + S D+ Sbjct: 620 PLRI--FAGHLADVNCTRYHPNSNYVATGSADR 650
>PRP46_YEAST (Q12417) Pre-mRNA-splicing factor PRP46 (Pre-mRNA-processing| protein 46) (Complexed with CEF1 protein 1) (PRP19-associated complex protein 50) (PRP nineteen-associated complex protein 50) Length = 451 Score = 53.9 bits (128), Expect = 2e-07 Identities = 49/157 (31%), Positives = 70/157 (44%), Gaps = 17/157 (10%) Frame = +1 Query: 37 VLTGHNHYVMCASFHPKE-DLVVSASLDQTVRVWDIGALRKKTVSPADDIMRLTQMNTD- 210 V+ GH +V C + P + + ++ S D T++VWD+ + KT A +M + + Sbjct: 134 VINGHLGWVRCVAIDPVDNEWFITGSNDTTMKVWDLATGKLKTTL-AGHVMTVRDVAVSD 192 Query: 211 ----LFG-GVDAVVK-YVLE---------GHDRGVNWASFHPTLPLIVSGADDRQVKLWR 345 LF D VK + LE GH GV S HPTL LI + D +KLW Sbjct: 193 RHPYLFSVSEDKTVKCWDLEKNQIIRDYYGHLSGVRTVSIHPTLDLIATAGRDSVIKLWD 252 Query: 346 MNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 M V TL GH ++ V +VS+S D Sbjct: 253 MR--TRIPVITLVGHKGPINQVQCTPVDPQVVSSSTD 287 Score = 48.1 bits (113), Expect = 1e-05 Identities = 37/161 (22%), Positives = 60/161 (37%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 + W+ + + GH V S HP DL+ +A D +++WD+ +T P Sbjct: 207 KCWDLEKNQIIRDYYGHLSGVRTVSIHPTLDLIATAGRDSVIKLWDM-----RTRIPV-- 259 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTK 360 L GH +N P P +VS + D V+LW + K Sbjct: 260 --------------------ITLVGHKGPINQVQCTPVDPQVVSSSTDATVRLWDVVAGK 299 Query: 361 AWEVDTLRGHMNNVSCVMFHAKQDIIVSNSEDKAFASGMPQ 483 +V L H +V H K+ + S D + G+ + Sbjct: 300 TMKV--LTHHKRSVRATALHPKEFSVASACTDDIRSWGLAE 338
>WDR57_HUMAN (Q96DI7) WD-repeat protein 57 (Prp8-binding protein) (hPRP8BP) (U5| snRNP-specific 40 kDa protein) (38 kDa splicing factor) Length = 357 Score = 53.9 bits (128), Expect = 2e-07 Identities = 39/158 (24%), Positives = 70/158 (44%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 ++W+ + + GH V S + ++S ++D TVRVWD+ + +P + Sbjct: 218 KVWDLRQNKLTYTMRGHADSVTGLSLSSEGSYLLSNAMDNTVRVWDV-----RPFAPKER 272 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTK 360 +++ Q N F ++ + S+ P I +G+ DR V +W + T Sbjct: 273 CVKIFQGNVHNF--------------EKNLLRCSWSPDGSKIAAGSADRFVYVW--DTTS 316 Query: 361 AWEVDTLRGHMNNVSCVMFHAKQDIIVSNSEDKAFASG 474 + L GH +++ V FH + II+S S DK G Sbjct: 317 RRILYKLPGHAGSINEVAFHPDEPIIISASSDKRLYMG 354 Score = 43.5 bits (101), Expect = 3e-04 Identities = 47/200 (23%), Positives = 76/200 (38%), Gaps = 58/200 (29%) Frame = +1 Query: 31 VAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI--GALRKKTVSPADDIMRLTQMN 204 + +L+GH V C FHP + SA D+ + +W++ T+ + N Sbjct: 59 IMLLSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYN 118 Query: 205 TD---LF-GGVDAVVKY----------VLEGHDRGVNWASFHPTL---PLIVSGADDRQV 333 TD LF D V L+GH VN S +P L+ +G+DD V Sbjct: 119 TDGSMLFSASTDKTVAVWDSETGERVKRLKGHTSFVN--SCYPARRGPQLVCTGSDDGTV 176 Query: 334 KLWRM---------------------------------NDTKAWEVD------TLRGHMN 396 KLW + ND K W++ T+RGH + Sbjct: 177 KLWDIRKKAAIQTFQNTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHAD 236 Query: 397 NVSCVMFHAKQDIIVSNSED 456 +V+ + ++ ++SN+ D Sbjct: 237 SVTGLSLSSEGSYLLSNAMD 256 Score = 34.3 bits (77), Expect = 0.18 Identities = 15/46 (32%), Positives = 27/46 (58%) Frame = +1 Query: 4 IWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI 141 +W+ SR + L GH + +FHP E +++SAS D+ + + +I Sbjct: 311 VWDTTSRRILYKLPGHAGSINEVAFHPDEPIIISASSDKRLYMGEI 356
>SCON2_NEUCR (Q01277) Sulfur controller 2 (SCON2)| Length = 650 Score = 53.9 bits (128), Expect = 2e-07 Identities = 41/170 (24%), Positives = 74/170 (43%), Gaps = 18/170 (10%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWD--IGALRKKTVSPA 174 +IWN ++ C+ L GH + F + ++S SLD T++VW+ G + Sbjct: 317 KIWNIETEECIRTLVGHTAGIRALQFDDSK--LISGSLDHTIKVWNWHTGECLSTFAAHT 374 Query: 175 DDIMRLTQMNTDLF--GGVDAVVK---------YVLEGHDRGVNWASFHPTLPLIVSGAD 321 D ++ + + L G D VK Y L+GH VN + S +D Sbjct: 375 DSVISV-HFDGHLLASGSSDKTVKIFDFNSKETYCLKGHSDWVNSTHVDIKSRTVFSASD 433 Query: 322 DRQVKLWRMNDTKAWEVDTLRGHMNNVSCVM-----FHAKQDIIVSNSED 456 D +KLW ++ + + T GH+ +V V+ + ++++ S+D Sbjct: 434 DTTIKLWDLDTRQV--IRTYEGHVGHVQQVLILPPEYEPDEEVLNGASQD 481 Score = 32.7 bits (73), Expect = 0.52 Identities = 28/90 (31%), Positives = 40/90 (44%), Gaps = 10/90 (11%) Frame = +1 Query: 217 GGVDAVVKY----------VLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAW 366 GG+D+ ++ L GH GV W+ T+ ++SGA+D VK W K Sbjct: 554 GGLDSTMRLWDSATGRCLRTLFGHLEGV-WSLAGDTIR-VISGANDGMVKTWEPRSGKC- 610 Query: 367 EVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 T GH V+CV ++ S SED Sbjct: 611 -DATYTGHCGPVTCV--GLSDSLMASGSED 637
>WDR57_MOUSE (Q6PE01) WD-repeat protein 57| Length = 358 Score = 53.5 bits (127), Expect = 3e-07 Identities = 39/158 (24%), Positives = 70/158 (44%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 ++W+ + + GH V S + ++S ++D TVRVWD+ + +P + Sbjct: 219 KVWDLRQNKLTYTMRGHADSVTGLSLSSEGSYLLSNAMDNTVRVWDV-----RPFAPKER 273 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTK 360 +++ Q N F ++ + S+ P I +G+ DR V +W + T Sbjct: 274 CVKIFQGNVHNF--------------EKNLLRCSWSPDGSKIAAGSADRFVYVW--DTTS 317 Query: 361 AWEVDTLRGHMNNVSCVMFHAKQDIIVSNSEDKAFASG 474 + L GH +++ V FH + II+S S DK G Sbjct: 318 RRVLYKLPGHAGSINEVAFHPDEPIILSASSDKRLYMG 355 Score = 43.5 bits (101), Expect = 3e-04 Identities = 47/200 (23%), Positives = 76/200 (38%), Gaps = 58/200 (29%) Frame = +1 Query: 31 VAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI--GALRKKTVSPADDIMRLTQMN 204 + +L+GH V C FHP + SA D+ + +W++ T+ + N Sbjct: 60 IMLLSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYN 119 Query: 205 TD---LF-GGVDAVVKY----------VLEGHDRGVNWASFHPTL---PLIVSGADDRQV 333 TD LF D V L+GH VN S +P L+ +G+DD V Sbjct: 120 TDGSMLFSASTDKTVAVWDSETGERVKRLKGHTSFVN--SCYPARRGPQLVCTGSDDGTV 177 Query: 334 KLWRM---------------------------------NDTKAWEVD------TLRGHMN 396 KLW + ND K W++ T+RGH + Sbjct: 178 KLWDIRKKAAVQTFQNTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHAD 237 Query: 397 NVSCVMFHAKQDIIVSNSED 456 +V+ + ++ ++SN+ D Sbjct: 238 SVTGLSLSSEGSYLLSNAMD 257 Score = 33.5 bits (75), Expect = 0.30 Identities = 15/46 (32%), Positives = 27/46 (58%) Frame = +1 Query: 4 IWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI 141 +W+ SR + L GH + +FHP E +++SAS D+ + + +I Sbjct: 312 VWDTTSRRVLYKLPGHAGSINEVAFHPDEPIILSASSDKRLYMGEI 357
>MET30_YEAST (P39014) F-box protein MET30 (Methionine requiring protein 30) (E3| ubiquitin ligase complex SCF(Met30) subunit MET30) Length = 640 Score = 53.5 bits (127), Expect = 3e-07 Identities = 34/138 (24%), Positives = 57/138 (41%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 R+WN+ + C++ GH+ V+ + K ++VS S D+TV+VW Sbjct: 365 RVWNYITGECISTYRGHSDSVLSVDSYQK--VIVSGSADKTVKVWH-------------- 408 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTK 360 V++ Y L GH VN HP S +DD +++W + Sbjct: 409 --------------VESRTCYTLRGHTEWVNCVKLHPKSFSCFSCSDDTTIRMWDIRTNS 454 Query: 361 AWEVDTLRGHMNNVSCVM 414 +V RGH+ V ++ Sbjct: 455 CLKV--FRGHVGQVQKII 470 Score = 53.1 bits (126), Expect = 4e-07 Identities = 45/163 (27%), Positives = 71/163 (43%), Gaps = 14/163 (8%) Frame = +1 Query: 10 NWQSRTC-VAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI--GALRKKTVSPADD 180 NW+ C + GH V+ F+ + L+ + S D T+ +WD+ G L ++ +D Sbjct: 287 NWRKGHCRIQEFKGHMDGVLTLQFNYR--LLFTGSYDSTIGIWDLFTGKLIRRLSGHSDG 344 Query: 181 IMRLTQMNTDLF-GGVDAVVKY----------VLEGHDRGVNWASFHPTLPLIVSGADDR 327 + L + L G +D ++ GH V S +IVSG+ D+ Sbjct: 345 VKTLYFDDRKLITGSLDKTIRVWNYITGECISTYRGHSDSV--LSVDSYQKVIVSGSADK 402 Query: 328 QVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 VK+W + + TLRGH V+CV H K S S+D Sbjct: 403 TVKVWHVESRTCY---TLRGHTEWVNCVKLHPKSFSCFSCSDD 442
>Y143_SYNY3 (P74442) Hypothetical WD-repeat protein slr0143| Length = 1191 Score = 53.5 bits (127), Expect = 3e-07 Identities = 46/153 (30%), Positives = 64/153 (41%), Gaps = 1/153 (0%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 R+W+W+S +AVL GH V A F P +VS D +R+WD+ Sbjct: 667 RLWHWRSGKTLAVLGGHTKSVDDAQFSPDGQTLVSVCRDGQIRLWDLDG----------- 715 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWR-MNDT 357 N G+ V + GVNW HP L+ ADD V+LW + Sbjct: 716 -------NLIRQFGLPEVAFF-------GVNW---HPNGNLLAVAADDGTVRLWTPQGEI 758 Query: 358 KAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 KA TL GH V+ V+F + S+S + Sbjct: 759 KA----TLSGHDEFVTRVVFTPDGKQLFSSSSN 787 Score = 53.1 bits (126), Expect = 4e-07 Identities = 44/153 (28%), Positives = 61/153 (39%), Gaps = 13/153 (8%) Frame = +1 Query: 37 VLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWD------------IGALRKKTVSPADD 180 VLTGH V + ++L+ SAS D TV +W G++ + SP Sbjct: 555 VLTGHRDGVTSVAISSHKNLIASASRDGTVHLWTPQGEFLREFTGHTGSIYRVDFSPNGK 614 Query: 181 IMRLT-QMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDT 357 I Q T +D + L+GH V SF P ++ S + DR V+LW Sbjct: 615 IFATAGQDQTVKIWDLDGNLLQTLKGHQDSVYSVSFSPDGEILASTSRDRTVRLWHWRSG 674 Query: 358 KAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 K V L GH +V F +VS D Sbjct: 675 KTLAV--LGGHTKSVDDAQFSPDGQTLVSVCRD 705
>TUP1_KLULA (P56094) Transcriptional repressor TUP1| Length = 682 Score = 53.1 bits (126), Expect = 4e-07 Identities = 47/180 (26%), Positives = 76/180 (42%), Gaps = 27/180 (15%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI-GALRKKTVSPAD 177 RIW+ +++ V L GH + + P + +VS S D+TVR+WD+ T+S D Sbjct: 431 RIWDLETKKIVMTLKGHEQDIYSLDYFPSGNKLVSGSGDRTVRIWDLTTGTCSLTLSIED 490 Query: 178 DIMRLTQMNTD----LFGGVDAVVK-------YVLE----------GHDRGVNWASFHPT 294 + + + G +D V+ +++E GH V F Sbjct: 491 GVTTVAVSPGEGKFIAAGSLDRTVRVWDSDTGFLVERLDSENELGTGHRDSVYSVVFTRD 550 Query: 295 LPLIVSGADDRQVKLWRMNDTKAWEVD-----TLRGHMNNVSCVMFHAKQDIIVSNSEDK 459 +VSG+ DR VKLW +N + T GH + V V + I+S S+D+ Sbjct: 551 GKGVVSGSLDRSVKLWNLNGLSGQKSHAECEVTYTGHKDFVLSVATTQNDEYILSGSKDR 610 Score = 33.1 bits (74), Expect = 0.40 Identities = 16/59 (27%), Positives = 32/59 (54%) Frame = +1 Query: 283 FHPTLPLIVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSEDK 459 F P + +GA+D+ +++W + K V TL+GH ++ + + + +VS S D+ Sbjct: 414 FSPDGKFLATGAEDKLIRIWDLETKKI--VMTLKGHEQDIYSLDYFPSGNKLVSGSGDR 470 Score = 29.6 bits (65), Expect = 4.4 Identities = 24/117 (20%), Positives = 45/117 (38%) Frame = +1 Query: 28 CVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDIMRLTQMNT 207 C TGH +V+ + ++ ++S S D+ V WD T S +M N+ Sbjct: 580 CEVTYTGHKDFVLSVATTQNDEYILSGSKDRGVLFWD-------TKSGNPLLMLQGHRNS 632 Query: 208 DLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVDT 378 + V GH G P + +G+ D + ++W+ + + + T Sbjct: 633 -------VISVTVANGHPLG-------PEYGVFATGSGDCKARIWKYSKKNSQQNST 675
>SWD3_SCHPO (O43017) Set1 complex component swd3 (Set1C component swd3)| (COMPASS component swd3) (Complex proteins associated with set1 protein swd3) Length = 380 Score = 53.1 bits (126), Expect = 4e-07 Identities = 38/156 (24%), Positives = 66/156 (42%), Gaps = 3/156 (1%) Frame = +1 Query: 1 RIWNWQSRTCVA---VLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSP 171 RI N++S + + L GH V C S P + + ++S D T+++W R Sbjct: 34 RIRNYESHSGFSEYCTLFGHEKSVTCVSVSPNKRWIATSSSDGTIKIWSALTFR------ 87 Query: 172 ADDIMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMN 351 ++ L GH RG++ + + S +DD+ +++W Sbjct: 88 ---------------------LECTLFGHYRGISQVKWATGSKYLASASDDKTIRIWDFE 126 Query: 352 DTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSEDK 459 K V L+GH N VS + F+ ++VS S D+ Sbjct: 127 --KRCSVRCLKGHTNYVSSIDFNPLGTLLVSGSWDE 160 Score = 50.1 bits (118), Expect = 3e-06 Identities = 21/47 (44%), Positives = 31/47 (65%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI 141 RIW+++ R V L GH +YV F+P L+VS S D+TVR+W++ Sbjct: 121 RIWDFEKRCSVRCLKGHTNYVSSIDFNPLGTLLVSGSWDETVRIWNL 167 Score = 42.0 bits (97), Expect = 9e-04 Identities = 21/59 (35%), Positives = 29/59 (49%), Gaps = 2/59 (3%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI--GALRKKTVSP 171 RIWN Q TC+ +L H+ ++ S L +AS D R+WD+ G K V P Sbjct: 163 RIWNLQDGTCLRMLPAHSEPIISVSISADGTLCATASYDGMARIWDVLSGQCLKTLVEP 221
>WSB2_MOUSE (O54929) WD repeat and SOCS box-containing protein 2 (WSB-2) (SOCS| box-containing WD protein SWiP-2) Length = 404 Score = 53.1 bits (126), Expect = 4e-07 Identities = 42/153 (27%), Positives = 63/153 (41%), Gaps = 1/153 (0%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLV-VSASLDQTVRVWDIGALRKKTVSPAD 177 +IW Q+ + L+GH V SF P L+ VSAS D+T+R+WD+ K+ Sbjct: 136 KIWEVQTGLLLLNLSGHQDVVRDLSFTPSGSLILVSASRDKTLRIWDLNKHGKQI----- 190 Query: 178 DIMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDT 357 VL GH + V S P ++ S A ++ V LW M Sbjct: 191 ---------------------QVLSGHLQWVYCCSISPDCSMLCSAAGEKSVFLWSMRSY 229 Query: 358 KAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 + L GH ++V F ++V+ S D Sbjct: 230 TL--IRKLEGHQSSVVSCDFSPDSALLVTASYD 260 Score = 42.0 bits (97), Expect = 9e-04 Identities = 36/151 (23%), Positives = 59/151 (39%) Frame = +1 Query: 4 IWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDI 183 +W+ +S T + L GH V+ F P L+V+AS D +V +WD P Sbjct: 223 LWSMRSYTLIRKLEGHQSSVVSCDFSPDSALLVTASYDTSVIMWD----------PYTGA 272 Query: 184 MRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKA 363 + +T L +D + H + F P + + ADDR +++W + Sbjct: 273 RLRSLHHTQLEPTMDD-----SDVHMSSLRSVCFSPEGLYLATVADDRLLRIWALE---- 323 Query: 364 WEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 + M N C F II + + D Sbjct: 324 LKAPVAFAPMTNGLCCTFFPHGGIIATGTRD 354 Score = 30.8 bits (68), Expect = 2.0 Identities = 21/68 (30%), Positives = 32/68 (47%), Gaps = 6/68 (8%) Frame = +1 Query: 274 WASFHPTLP-----LIVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQD-I 435 WA HP P ++ +G +D Q+K+W + + L GH + V + F I Sbjct: 111 WARHHPQAPDVSCLILATGLNDGQIKIWEVQ--TGLLLLNLSGHQDVVRDLSFTPSGSLI 168 Query: 436 IVSNSEDK 459 +VS S DK Sbjct: 169 LVSASRDK 176
>WSB2_HUMAN (Q9NYS7) WD repeat and SOCS box-containing protein 2 (WSB-2) (CS| box-containing WD protein) Length = 404 Score = 53.1 bits (126), Expect = 4e-07 Identities = 42/153 (27%), Positives = 63/153 (41%), Gaps = 1/153 (0%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLV-VSASLDQTVRVWDIGALRKKTVSPAD 177 +IW Q+ + L+GH V SF P L+ VSAS D+T+R+WD+ K+ Sbjct: 136 KIWEVQTGLLLLNLSGHQDVVRDLSFTPSGSLILVSASRDKTLRIWDLNKHGKQI----- 190 Query: 178 DIMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDT 357 VL GH + V S P ++ S A ++ V LW M Sbjct: 191 ---------------------QVLSGHLQWVYCCSISPDCSMLCSAAGEKSVFLWSMRSY 229 Query: 358 KAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 + L GH ++V F ++V+ S D Sbjct: 230 TL--IRKLEGHQSSVVSCDFSPDSALLVTASYD 260 Score = 43.5 bits (101), Expect = 3e-04 Identities = 37/157 (23%), Positives = 61/157 (38%), Gaps = 6/157 (3%) Frame = +1 Query: 4 IWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWD------IGALRKKTV 165 +W+ +S T + L GH V+ F P L+V+AS D V +WD + +L V Sbjct: 223 LWSMRSYTLIRKLEGHQSSVVSCDFSPDSALLVTASYDTNVIMWDPYTGERLRSLHHTQV 282 Query: 166 SPADDIMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWR 345 PA D ++D+ H + F P + + ADDR +++W Sbjct: 283 DPAMD-------DSDV--------------HISSLRSVCFSPEGLYLATVADDRLLRIWA 321 Query: 346 MNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 + + M N C F +I + + D Sbjct: 322 LE----LKTPIAFAPMTNGLCCTFFPHGGVIATGTRD 354 Score = 31.2 bits (69), Expect = 1.5 Identities = 21/68 (30%), Positives = 33/68 (48%), Gaps = 6/68 (8%) Frame = +1 Query: 274 WASFHPTLP-----LIVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQD-I 435 WA HP +P ++ +G +D Q+K+W + + L GH + V + F I Sbjct: 111 WARHHPQVPDVSCLVLATGLNDGQIKIWEVQ--TGLLLLNLSGHQDVVRDLSFTPSGSLI 168 Query: 436 IVSNSEDK 459 +VS S DK Sbjct: 169 LVSASRDK 176
>PRP46_SCHPO (O13615) Pre-mRNA-splicing factor prp46 (Pre-mRNA-processing| protein 5) (Complexed with cdc5 protein 1) Length = 473 Score = 53.1 bits (126), Expect = 4e-07 Identities = 32/144 (22%), Positives = 57/144 (39%) Frame = +1 Query: 25 TCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDIMRLTQMN 204 T + V++GH +V C P + + D+T+++WD+ + Sbjct: 154 TLMRVISGHLGWVRCVDVEPGNQWFCTGAGDRTIKIWDLAS------------------- 194 Query: 205 TDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVDTLR 384 V+K L GH V + P P + S +D+ VK W + K + Sbjct: 195 --------GVLKLTLTGHIATVRGLAVSPRHPYLFSCGEDKMVKCWDLETNKV--IRHYH 244 Query: 385 GHMNNVSCVMFHAKQDIIVSNSED 456 GH++ V + H D++V+ D Sbjct: 245 GHLSGVYALKLHPTLDVLVTAGRD 268 Score = 47.0 bits (110), Expect = 3e-05 Identities = 35/128 (27%), Positives = 61/128 (47%), Gaps = 14/128 (10%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRK-KTVSPAD 177 R+W+ ++R V VL+GH V + + VV+ S+D T+R+WD+ A + T++ Sbjct: 272 RVWDMRTRQNVHVLSGHKSTVASLAVQEFDPQVVTGSMDSTIRLWDLAAGKTLTTLTHHK 331 Query: 178 DIMRLTQMNTDLF----GGVDAVVKYV---------LEGHDRGVNWASFHPTLPLIVSGA 318 +R ++ D F G D + + EGH+ VN S + ++ SGA Sbjct: 332 KTVRALSLHPDEFTFASGSSDNIKHWKFPEGAFMGNFEGHNAIVNTLSINSD-NVMFSGA 390 Query: 319 DDRQVKLW 342 D+ + W Sbjct: 391 DNGSMCFW 398 Score = 46.2 bits (108), Expect = 5e-05 Identities = 36/152 (23%), Positives = 57/152 (37%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 + W+ ++ + GH V HP D++V+A D RVWD+ Sbjct: 230 KCWDLETNKVIRHYHGHLSGVYALKLHPTLDVLVTAGRDAVARVWDM------------- 276 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTK 360 T+ N +VL GH V + P +V+G+ D ++LW + K Sbjct: 277 ---RTRQNV-----------HVLSGHKSTVASLAVQEFDPQVVTGSMDSTIRLWDLAAGK 322 Query: 361 AWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 + TL H V + H + S S D Sbjct: 323 T--LTTLTHHKKTVRALSLHPDEFTFASGSSD 352 Score = 44.3 bits (103), Expect = 2e-04 Identities = 35/152 (23%), Positives = 58/152 (38%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 +IW+ S LTGH V + P+ + S D+ V+ WD+ Sbjct: 188 KIWDLASGVLKLTLTGHIATVRGLAVSPRHPYLFSCGEDKMVKCWDL------------- 234 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTK 360 + V+++ GH GV HPTL ++V+ D ++W M + Sbjct: 235 -------------ETNKVIRH-YHGHLSGVYALKLHPTLDVLVTAGRDAVARVWDMRTRQ 280 Query: 361 AWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 V L GH + V+ + +V+ S D Sbjct: 281 --NVHVLSGHKSTVASLAVQEFDPQVVTGSMD 310
>PRP46_CRYNE (Q5KDR4) Pre-mRNA-splicing factor PRP46 (Pre-mRNA-processing| protein 46) Length = 473 Score = 53.1 bits (126), Expect = 4e-07 Identities = 45/155 (29%), Positives = 72/155 (46%), Gaps = 15/155 (9%) Frame = +1 Query: 37 VLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI--GALRKKTVSPADDI--MRLTQMN 204 V++GH +V + P + + D+ +++WD+ G L+ I + ++ + Sbjct: 177 VISGHMGWVRAVAMDPGNQWFATGAGDRVIKIWDLASGELKLSLTGHISTIRGLAVSDRH 236 Query: 205 TDLFG-GVDAVVK-YVLE---------GHDRGVNWASFHPTLPLIVSGADDRQVKLWRMN 351 LF D +VK + LE GH GV S HPTL ++V+G D V++W M Sbjct: 237 PYLFSCAEDKMVKCWDLETNKVIRHYHGHFSGVYSLSVHPTLDVLVTGGRDASVRVWDMR 296 Query: 352 DTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 T+A + TL GH + V V I+S S D Sbjct: 297 -TRA-NIFTLTGHTSTVGDVKTQDSDPQIISGSMD 329 Score = 45.4 bits (106), Expect = 8e-05 Identities = 37/150 (24%), Positives = 59/150 (39%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 + W+ ++ + GH V S HP D++V+ D +VRVWD+ Sbjct: 249 KCWDLETNKVIRHYHGHFSGVYSLSVHPTLDVLVTGGRDASVRVWDM------------- 295 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTK 360 T+ N + L GH V + P I+SG+ D V+LW + K Sbjct: 296 ---RTRANI-----------FTLTGHTSTVGDVKTQDSDPQIISGSMDSTVRLWDLAAGK 341 Query: 361 AWEVDTLRGHMNNVSCVMFHAKQDIIVSNS 450 ++TL H +V + H + S S Sbjct: 342 C--MNTLTHHKKSVRALAIHPTEYSFASAS 369 Score = 42.4 bits (98), Expect = 7e-04 Identities = 17/49 (34%), Positives = 28/49 (57%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGA 147 R+W+ ++R + LTGH V + ++S S+D TVR+WD+ A Sbjct: 291 RVWDMRTRANIFTLTGHTSTVGDVKTQDSDPQIISGSMDSTVRLWDLAA 339
>CWF17_SCHPO (O94620) Cell cycle control protein cwf17| Length = 340 Score = 52.4 bits (124), Expect = 6e-07 Identities = 37/158 (23%), Positives = 65/158 (41%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 +IW+ ++ C VL GH + + ++S S+D TVR++D+ Sbjct: 202 KIWDLRNNHCSHVLKGHKDIITSLAISKDGSSLLSNSMDNTVRIFDVKPFAS-------- 253 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTK 360 Q +F G + G + + ++ + +G+ D+ V +W Sbjct: 254 ----AQRQLQIFEG-------AIHGQEHNLLGVAWSRNSRFVGAGSSDKNVYVWSATGDL 302 Query: 361 AWEVDTLRGHMNNVSCVMFHAKQDIIVSNSEDKAFASG 474 + L GH +V+ V FH QDII+S S D+ G Sbjct: 303 RY---VLPGHEGSVNHVDFHPHQDIILSCSSDRTIFLG 337 Score = 28.9 bits (63), Expect = 7.5 Identities = 20/69 (28%), Positives = 31/69 (44%), Gaps = 1/69 (1%) Frame = +1 Query: 253 GHDRGVNWASFHPTLPLIVSGADDRQVKLWRM-NDTKAWEVDTLRGHMNNVSCVMFHAKQ 429 GH V A F P+ SG DRQ+ LW + D K + V L G ++ + + Sbjct: 48 GHTAEVLVARFDPSGSYFASGGMDRQILLWNVFGDVKNYGV--LNGCKGAITDLQWSRDS 105 Query: 430 DIIVSNSED 456 ++ +S D Sbjct: 106 RVVYCSSSD 114
>TAF5_YEAST (P38129) Transcription initiation factor TFIID subunit 5| (TBP-associated factor 5) (TBP-associated factor 90 kDa) (TAFII-90) Length = 798 Score = 52.4 bits (124), Expect = 6e-07 Identities = 41/145 (28%), Positives = 61/145 (42%) Frame = +1 Query: 25 TCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDIMRLTQMN 204 TC L GH+ V SF P ++S S D+TVR+W M+ Sbjct: 517 TC-KTLVGHSGTVYSTSFSPDNKYLLSGSEDKTVRLWS--------------------MD 555 Query: 205 TDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVDTLR 384 T A+V Y +GH+ V SF P + + D+ +LW + + + Sbjct: 556 THT-----ALVSY--KGHNHPVWDVSFSPLGHYFATASHDQTARLWSCDHI--YPLRIFA 606 Query: 385 GHMNNVSCVMFHAKQDIIVSNSEDK 459 GH+N+V CV FH + + S DK Sbjct: 607 GHLNDVDCVSFHPNGCYVFTGSSDK 631 Score = 49.3 bits (116), Expect = 5e-06 Identities = 31/114 (27%), Positives = 45/114 (39%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 R+W+ + T + GHNH V SF P +AS DQT R+W D Sbjct: 550 RLWSMDTHTALVSYKGHNHPVWDVSFSPLGHYFATASHDQTARLWS-----------CDH 598 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLW 342 I L + GH V+ SFHP + +G+ D+ ++W Sbjct: 599 IYPLR----------------IFAGHLNDVDCVSFHPNGCYVFTGSSDKTCRMW 636 Score = 43.9 bits (102), Expect = 2e-04 Identities = 35/153 (22%), Positives = 63/153 (41%), Gaps = 1/153 (0%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 R+W+ + + GH + V C SFHP V + S D+T R+WD VS D Sbjct: 592 RLWSCDHIYPLRIFAGHLNDVDCVSFHPNGCYVFTGSSDKTCRMWD--------VSTGDS 643 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTK 360 + + GH V + P + +G++D + +W + K Sbjct: 644 VR-------------------LFLGHTAPVISIAVCPDGRWLSTGSEDGIINVWDIGTGK 684 Query: 361 AWEVDTLRGHMNNVSCVMFHAKQ-DIIVSNSED 456 + +RGH N + ++K+ ++++S D Sbjct: 685 --RLKQMRGHGKNAIYSLSYSKEGNVLISGGAD 715 Score = 31.2 bits (69), Expect = 1.5 Identities = 17/58 (29%), Positives = 31/58 (53%), Gaps = 1/58 (1%) Frame = +1 Query: 4 IWNWQSRTCVAVLTGHNHYVMCASFHPKE-DLVVSASLDQTVRVWDIGALRKKTVSPA 174 +W+ + + + GH + + + KE ++++S D TVRVWD L+K T P+ Sbjct: 677 VWDIGTGKRLKQMRGHGKNAIYSLSYSKEGNVLISGGADHTVRVWD---LKKATTEPS 731
>GBLP_NICPL (P93340) Guanine nucleotide-binding protein beta subunit-like| protein Length = 326 Score = 52.0 bits (123), Expect = 8e-07 Identities = 41/157 (26%), Positives = 64/157 (40%), Gaps = 5/157 (3%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 R+W+ Q+ T GH V+ +F +VSAS D+++R+W+ T+ Sbjct: 89 RLWDLQAGTTARRFVGHTKDVLSVAFSADNRQIVSASRDKSIRLWN-------TLGEC-- 139 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWAS---FHPT--LPLIVSGADDRQVKLWR 345 KY+++ D +W S F P P IVSG+ DR VK+W Sbjct: 140 -------------------KYIIQDGDSHSDWVSCVRFSPNNLQPTIVSGSWDRTVKIWN 180 Query: 346 MNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 + + K TL GH V+ + S +D Sbjct: 181 LTNCKLRA--TLAGHTGYVNTTAVSPDGSLCASGGKD 215 Score = 33.9 bits (76), Expect = 0.23 Identities = 16/52 (30%), Positives = 23/52 (44%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRK 156 +IWN + A L GH YV + P L S D + +WD+ +K Sbjct: 177 KIWNLTNCKLRATLAGHTGYVNTTAVSPDGSLCASGGKDGVILLWDLAEGKK 228
>WSB1_HUMAN (Q9Y6I7) WD repeat and SOCS box-containing protein 1 (WSB-1) (SOCS| box-containing WD protein SWiP-1) Length = 421 Score = 52.0 bits (123), Expect = 8e-07 Identities = 40/154 (25%), Positives = 63/154 (40%), Gaps = 3/154 (1%) Frame = +1 Query: 4 IWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDI 183 +WN T + L GH+H V+ F P L+ +AS D V +WD D + Sbjct: 240 LWNMDKYTMIRKLEGHHHDVVACDFSPDGALLATASYDTRVYIWD--------PHNGDIL 291 Query: 184 MRLTQM---NTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMND 354 M + T +F G +DR V SF + S ADD+ V+ WR+++ Sbjct: 292 MEFGHLFPPPTPIFAG---------GANDRWVRSVSFSHDGLHVASLADDKMVRFWRIDE 342 Query: 355 TKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 +V L +N C F ++ + + D Sbjct: 343 DYPVQVAPL----SNGLCCAFSTDGSVLAAGTHD 372 Score = 43.5 bits (101), Expect = 3e-04 Identities = 39/153 (25%), Positives = 60/153 (39%), Gaps = 1/153 (0%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLV-VSASLDQTVRVWDIGALRKKTVSPAD 177 +IW+ + + L H V +F P L+ VSAS D+T+RVWD+ Sbjct: 153 KIWDVYTGKLLLNLVDHTEVVRDLTFAPDGSLILVSASRDKTLRVWDLKD---------- 202 Query: 178 DIMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDT 357 D + VL GH V +F P ++ S + V LW M+ Sbjct: 203 ----------------DGNMMKVLRGHQNWVYSCAFSPDSSMLCSVGASKAVFLWNMD-- 244 Query: 358 KAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 K + L GH ++V F ++ + S D Sbjct: 245 KYTMIRKLEGHHHDVVACDFSPDGALLATASYD 277
>PRP19_HUMAN (Q9UMS4) Pre-mRNA-splicing factor 19 (PRP19/PSO4 homolog) (Nuclear| matrix protein 200) (hPso4) Length = 504 Score = 52.0 bits (123), Expect = 8e-07 Identities = 39/171 (22%), Positives = 70/171 (40%), Gaps = 18/171 (10%) Frame = +1 Query: 4 IWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI-------------G 144 +++ S +A L GH V FHP +DLV SAS D T+R+W + Sbjct: 248 VFDKSSEQILATLKGHTKKVTSVVFHPSQDLVFSASPDATIRIWSVPNASCVQVVRAHES 307 Query: 145 ALRKKTVSPADDIMRLTQMNTDLFGGVD-----AVVKYVLEGHDRGVNWASFHPTLPLIV 309 A+ ++ D + L+ + + D + K E + A FHP + Sbjct: 308 AVTGLSLHATGDYL-LSSSDDQYWAFSDIQTGRVLTKVTDETSGCSLTCAQFHPDGLIFG 366 Query: 310 SGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSEDKA 462 +G D Q+K+W + + V GH ++ + F + + ++D + Sbjct: 367 TGTMDSQIKIWDLKERT--NVANFPGHSGPITSIAFSENGYYLATAADDSS 415 Score = 47.0 bits (110), Expect = 3e-05 Identities = 24/89 (26%), Positives = 46/89 (51%) Frame = +1 Query: 202 NTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVDTL 381 N +F + L+GH + V FHP+ L+ S + D +++W + + V + Sbjct: 245 NVVVFDKSSEQILATLKGHTKKVTSVVFHPSQDLVFSASPDATIRIWSVPNASC--VQVV 302 Query: 382 RGHMNNVSCVMFHAKQDIIVSNSEDKAFA 468 R H + V+ + HA D ++S+S+D+ +A Sbjct: 303 RAHESAVTGLSLHATGDYLLSSSDDQYWA 331 Score = 34.3 bits (77), Expect = 0.18 Identities = 18/73 (24%), Positives = 35/73 (47%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 +IW+ + RT VA GH+ + +F + +A+ D +V++WD+ L+ D+ Sbjct: 375 KIWDLKERTNVANFPGHSGPITSIAFSENGYYLATAADDSSVKLWDLRKLKNFKTLQLDN 434 Query: 181 IMRLTQMNTDLFG 219 + + D G Sbjct: 435 NFEVKSLIFDQSG 447 Score = 34.3 bits (77), Expect = 0.18 Identities = 17/51 (33%), Positives = 30/51 (58%) Frame = +1 Query: 304 IVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 I++G D+ V ++ + + + TL+GH V+ V+FH QD++ S S D Sbjct: 237 ILTGGADKNVVVFDKSSEQI--LATLKGHTKKVTSVVFHPSQDLVFSASPD 285
>WSB1_MOUSE (O54927) WD repeat and SOCS box-containing protein 1 (WSB-1)| Length = 421 Score = 51.6 bits (122), Expect = 1e-06 Identities = 40/151 (26%), Positives = 61/151 (40%) Frame = +1 Query: 4 IWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDI 183 +WN T + L GH+H V+ F P L+ +AS D V VWD + Sbjct: 240 LWNMDKYTMIRKLEGHHHDVVACDFSPDGALLATASYDTRVYVWD-----PHNGDLLMEF 294 Query: 184 MRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKA 363 L T +F G +DR V SF + S ADD+ V+ WR+++ Sbjct: 295 GHLFPSPTPIFAG---------GANDRWVRAVSFSHDGLHVASLADDKMVRFWRIDEDCP 345 Query: 364 WEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 +V L +N C F ++ + + D Sbjct: 346 VQVAPL----SNGLCCAFSTDGSVLAAGTHD 372 Score = 39.3 bits (90), Expect = 0.006 Identities = 38/153 (24%), Positives = 59/153 (38%), Gaps = 1/153 (0%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLV-VSASLDQTVRVWDIGALRKKTVSPAD 177 +IW+ + + L H V +F P L+ VSAS D+T+RVWD+ Sbjct: 153 KIWDVYTGKLLLNLVDHIEMVRDLTFAPDGSLLLVSASRDKTLRVWDLKD---------- 202 Query: 178 DIMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDT 357 D + VL H V +F P ++ S + V LW M+ Sbjct: 203 ----------------DGNMVKVLRAHQNWVYSCAFSPDCSMLCSVGASKAVFLWNMD-- 244 Query: 358 KAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 K + L GH ++V F ++ + S D Sbjct: 245 KYTMIRKLEGHHHDVVACDFSPDGALLATASYD 277
>GBLP_CHLRE (P25387) Guanine nucleotide-binding protein beta subunit-like| protein Length = 318 Score = 51.6 bits (122), Expect = 1e-06 Identities = 39/154 (25%), Positives = 61/154 (39%), Gaps = 2/154 (1%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 R+W+ + T GH V+ +F +VS S D+T+++W+ K T+ Sbjct: 89 RLWDLNTGTTTRRFVGHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLGECKYTIGEP-- 146 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHP--TLPLIVSGADDRQVKLWRMND 354 EGH V+ F P T P+IVSG D+ VK+W + + Sbjct: 147 -----------------------EGHTEWVSCVRFSPMTTNPIIVSGGWDKMVKVWNLTN 183 Query: 355 TKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 K + L GH V+ V + S +D Sbjct: 184 CKL--KNNLVGHHGYVNTVTVSPDGSLCASGGKD 215 Score = 47.4 bits (111), Expect = 2e-05 Identities = 46/172 (26%), Positives = 71/172 (41%), Gaps = 24/172 (13%) Frame = +1 Query: 16 QSRTCVAVLTGHNHYV--MCASFHPKEDLVVSASLDQTVRVWDI-------GALRKKTVS 168 ++ T A L GH ++V + P + ++SAS D++V VW++ G RK Sbjct: 3 ETLTLRATLKGHTNWVTAIATPLDPSSNTLLSASRDKSVLVWELERSESNYGYARKALRG 62 Query: 169 PA---DDIMRLTQMNTDLFGGVDAVVKYV----------LEGHDRGVNWASFHPTLPLIV 309 + D++ + L G D ++ GH + V +F IV Sbjct: 63 HSHFVQDVVISSDGQFCLTGSWDGTLRLWDLNTGTTTRRFVGHTKDVLSVAFSVDNRQIV 122 Query: 310 SGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFH--AKQDIIVSNSEDK 459 SG+ D+ +KLW + + GH VSCV F IIVS DK Sbjct: 123 SGSRDKTIKLWNTLGECKYTIGEPEGHTEWVSCVRFSPMTTNPIIVSGGWDK 174 Score = 30.0 bits (66), Expect = 3.3 Identities = 15/62 (24%), Positives = 26/62 (41%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 ++WN + L GH+ YV + P L S D +WD+ ++ A D Sbjct: 177 KVWNLTNCKLKNNLVGHHGYVNTVTVSPDGSLCASGGKDGIAMLWDLAEGKRLYSLDAGD 236 Query: 181 IM 186 ++ Sbjct: 237 VI 238
>WDR48_MOUSE (Q8BH57) WD-repeat protein 48| Length = 676 Score = 51.6 bits (122), Expect = 1e-06 Identities = 41/177 (23%), Positives = 69/177 (38%), Gaps = 24/177 (13%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSP--- 171 ++WN C++ L H YV ++ ++LV SA LD+ + +WD+ L T S Sbjct: 100 KVWNAHKGFCMSTLRTHKDYVKALAYAKDKELVASAGLDRQIFLWDVNTLTALTASNNTV 159 Query: 172 --------ADDI--MRLTQMNTDLFGGVDAVVKYV-----------LEGHDRGVNWASFH 288 D I + + Q+ T + G V V L+GH V H Sbjct: 160 TTSSLSGNKDSIYSLAMNQLGTIIVSGSTEKVLRVWDPRTCAKLMKLKGHTDNVKALLLH 219 Query: 289 PTLPLIVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSEDK 459 +SG+ D ++LW + + + T R H V + + + S D+ Sbjct: 220 RDGTQCLSGSSDGTIRLWSLGQQRC--IATYRVHDEGVWALQVNDAFTHVYSGGRDR 274 Score = 33.9 bits (76), Expect = 0.23 Identities = 38/159 (23%), Positives = 69/159 (43%), Gaps = 24/159 (15%) Frame = +1 Query: 52 NHYVMCASFHPKEDLVVSASLDQTVRVWD------IGALR--------------KKTVSP 171 N V+C + ++SAS D TV+VW+ + LR K+ V+ Sbjct: 79 NDVVLCCN----GKTLISASSDTTVKVWNAHKGFCMSTLRTHKDYVKALAYAKDKELVAS 134 Query: 172 A--DDIMRLTQMN--TDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKL 339 A D + L +N T L + V L G+ + + + +IVSG+ ++ +++ Sbjct: 135 AGLDRQIFLWDVNTLTALTASNNTVTTSSLSGNKDSIYSLAMNQLGTIIVSGSTEKVLRV 194 Query: 340 WRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 W + ++ L+GH +NV ++ H +S S D Sbjct: 195 W--DPRTCAKLMKLKGHTDNVKALLLHRDGTQCLSGSSD 231
>WDR39_HUMAN (O76071) WD-repeat protein 39 (Ciao 1 protein)| Length = 339 Score = 51.6 bits (122), Expect = 1e-06 Identities = 43/156 (27%), Positives = 71/156 (45%), Gaps = 4/156 (2%) Frame = +1 Query: 1 RIWNWQ--SRTCVAVLT-GHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSP 171 RIW + S C +VL+ GH V ++ P + + SAS D T +W KK Sbjct: 41 RIWGTEGDSWICKSVLSEGHQRTVRKVAWSPCGNYLASASFDATTCIW------KKN--- 91 Query: 172 ADDIMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMN 351 DD +T LEGH+ V ++ P+ L+ + + D+ V +W ++ Sbjct: 92 QDDFECVT----------------TLEGHENEVKSVAWAPSGNLLATCSRDKSVWVWEVD 135 Query: 352 DTKAWE-VDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 + +E V L H +V V++H Q+++ S S D Sbjct: 136 EEDEYECVSVLNSHTQDVKHVVWHPSQELLASASYD 171 Score = 49.3 bits (116), Expect = 5e-06 Identities = 40/154 (25%), Positives = 64/154 (41%), Gaps = 2/154 (1%) Frame = +1 Query: 4 IW--NWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPAD 177 IW N CV L GH + V ++ P +L+ + S D++V VW+ V D Sbjct: 87 IWKKNQDDFECVTTLEGHENEVKSVAWAPSGNLLATCSRDKSVWVWE--------VDEED 138 Query: 178 DIMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDT 357 + ++ VL H + V +HP+ L+ S + D VKL+R + Sbjct: 139 EYECVS----------------VLNSHTQDVKHVVWHPSQELLASASYDDTVKLYREEED 182 Query: 358 KAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSEDK 459 TL GH + V + F + S S+D+ Sbjct: 183 DWVCCATLEGHESTVWSLAFDPSGQRLASCSDDR 216 Score = 48.5 bits (114), Expect = 9e-06 Identities = 34/119 (28%), Positives = 52/119 (43%), Gaps = 5/119 (4%) Frame = +1 Query: 4 IWNWQ-----SRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVS 168 +W W+ CV+VL H V +HP ++L+ SAS D TV+++ Sbjct: 129 VWVWEVDEEDEYECVSVLNSHTQDVKHVVWHPSQELLASASYDDTVKLY----------R 178 Query: 169 PADDIMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWR 345 +D D V LEGH+ V +F P+ + S +DDR V++WR Sbjct: 179 EEED---------------DWVCCATLEGHESTVWSLAFDPSGQRLASCSDDRTVRIWR 222 Score = 38.9 bits (89), Expect = 0.007 Identities = 24/78 (30%), Positives = 37/78 (47%), Gaps = 1/78 (1%) Frame = +1 Query: 232 VVKYVL-EGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSC 408 + K VL EGH R V ++ P + S + D +W+ N V TL GH N V Sbjct: 51 ICKSVLSEGHQRTVRKVAWSPCGNYLASASFDATTCIWKKNQDDFECVTTLEGHENEVKS 110 Query: 409 VMFHAKQDIIVSNSEDKA 462 V + +++ + S DK+ Sbjct: 111 VAWAPSGNLLATCSRDKS 128
>GBLP_BRANA (Q39336) Guanine nucleotide-binding protein beta subunit-like| protein Length = 327 Score = 51.6 bits (122), Expect = 1e-06 Identities = 42/154 (27%), Positives = 63/154 (40%), Gaps = 2/154 (1%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 R+W+ + GH V+ +F +VSAS D+T+++W+ K T+S Sbjct: 88 RLWDLAAGVSTRRFVGHTKDVLSVAFSLDNRQIVSASRDRTIKLWNTLGECKYTISE--- 144 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTL--PLIVSGADDRQVKLWRMND 354 GG EGH V+ F P P IVS + D+ VK+W +++ Sbjct: 145 ------------GG---------EGHRDWVSCVRFSPNTLQPTIVSASCDKTVKVWNLSN 183 Query: 355 TKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 K TL GH VS V + S +D Sbjct: 184 CKL--RSTLAGHTGYVSTVAVSPDGSLCASGGKD 215 Score = 38.5 bits (88), Expect = 0.009 Identities = 40/146 (27%), Positives = 64/146 (43%), Gaps = 23/146 (15%) Frame = +1 Query: 91 DLVVSASLDQTVRVWDI-------GALRKKTVSPA---DDIMRLTQMNTDLFGGVDAVVK 240 D +VSAS D+++ VW + G +++ + +D++ + L G D ++ Sbjct: 29 DTIVSASRDKSIIVWKLTKDDKSYGVRQRRLTGHSHFVEDVVLSSDGQFALSGSWDGELR 88 Query: 241 Y----------VLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWR-MNDTKAWEVDTLRG 387 GH + V +F IVS + DR +KLW + + K + G Sbjct: 89 LWDLAAGVSTRRFVGHTKDVLSVAFSLDNRQIVSASRDRTIKLWNTLGECKYTISEGGEG 148 Query: 388 HMNNVSCVMF--HAKQDIIVSNSEDK 459 H + VSCV F + Q IVS S DK Sbjct: 149 HRDWVSCVRFSPNTLQPTIVSASCDK 174 Score = 33.5 bits (75), Expect = 0.30 Identities = 15/52 (28%), Positives = 23/52 (44%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRK 156 ++WN + + L GH YV + P L S D V +WD+ +K Sbjct: 177 KVWNLSNCKLRSTLAGHTGYVSTVAVSPDGSLCASGGKDGVVLLWDLAEGKK 228
>GBLP_ARATH (O24456) Guanine nucleotide-binding protein beta subunit-like| protein (WD-40 repeat auxin-dependent protein ARCA) Length = 327 Score = 51.2 bits (121), Expect = 1e-06 Identities = 42/154 (27%), Positives = 63/154 (40%), Gaps = 2/154 (1%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 R+W+ + GH V+ +F +VSAS D+T+++W+ K T+S Sbjct: 88 RLWDLAAGVSTRRFVGHTKDVLSVAFSLDNRQIVSASRDRTIKLWNTLGECKYTISE--- 144 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTL--PLIVSGADDRQVKLWRMND 354 GG EGH V+ F P P IVS + D+ VK+W +++ Sbjct: 145 ------------GG---------EGHRDWVSCVRFSPNTLQPTIVSASWDKTVKVWNLSN 183 Query: 355 TKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 K TL GH VS V + S +D Sbjct: 184 CKL--RSTLAGHTGYVSTVAVSPDGSLCASGGKD 215 Score = 39.3 bits (90), Expect = 0.006 Identities = 39/146 (26%), Positives = 65/146 (44%), Gaps = 23/146 (15%) Frame = +1 Query: 91 DLVVSASLDQTVRVWDI-------GALRKKTVSPA---DDIMRLTQMNTDLFGGVDAVVK 240 D++VSAS D+++ +W + G +++ + +D++ + L G D ++ Sbjct: 29 DIIVSASRDKSIILWKLTKDDKAYGVAQRRLTGHSHFVEDVVLSSDGQFALSGSWDGELR 88 Query: 241 Y----------VLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWR-MNDTKAWEVDTLRG 387 GH + V +F IVS + DR +KLW + + K + G Sbjct: 89 LWDLAAGVSTRRFVGHTKDVLSVAFSLDNRQIVSASRDRTIKLWNTLGECKYTISEGGEG 148 Query: 388 HMNNVSCVMF--HAKQDIIVSNSEDK 459 H + VSCV F + Q IVS S DK Sbjct: 149 HRDWVSCVRFSPNTLQPTIVSASWDK 174 Score = 38.5 bits (88), Expect = 0.009 Identities = 28/107 (26%), Positives = 42/107 (39%), Gaps = 2/107 (1%) Frame = +1 Query: 46 GHNHYVMCASFHPK--EDLVVSASLDQTVRVWDIGALRKKTVSPADDIMRLTQMNTDLFG 219 GH +V C F P + +VSAS D+TV+VW++ + ++ Sbjct: 148 GHRDWVSCVRFSPNTLQPTIVSASWDKTVKVWNLSNCKLRST------------------ 189 Query: 220 GVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTK 360 L GH V+ + P L SG D V LW + + K Sbjct: 190 ---------LAGHTGYVSTVAVSPDGSLCASGGKDGVVLLWDLAEGK 227 Score = 33.5 bits (75), Expect = 0.30 Identities = 15/52 (28%), Positives = 23/52 (44%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRK 156 ++WN + + L GH YV + P L S D V +WD+ +K Sbjct: 177 KVWNLSNCKLRSTLAGHTGYVSTVAVSPDGSLCASGGKDGVVLLWDLAEGKK 228
>TAF5L_HUMAN (O75529) TAF5-like RNA polymerase II p300/CBP-associated| factor-associated factor 65 kDa subunit 5L (PCAF-associated factor 65 beta) (PAF65-beta) Length = 589 Score = 51.2 bits (121), Expect = 1e-06 Identities = 40/172 (23%), Positives = 66/172 (38%), Gaps = 24/172 (13%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI------------- 141 R+W++ + + GH V C FHP + + + S D+TVR+W Sbjct: 409 RLWSFDRTYPLRIYAGHLADVDCVKFHPNSNYLATGSTDKTVRLWSAQQGNSVRLFTGHR 468 Query: 142 GALRKKTVSPADDIMRLT--QMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSG 315 G + SP + L+ + L GH + +F P LI S Sbjct: 469 GPVLSLAFSPNGKYLASAGEDQRLKLWDLASGTLYKELRGHTDNITSLTFSPDSGLIASA 528 Query: 316 ADDRQVKLWRMNDT---------KAWEVDTLRGHMNNVSCVMFHAKQDIIVS 444 + D V++W + +T + V G M+NV V F A ++V+ Sbjct: 529 SMDNSVRVWDIRNTYCSAPADGSSSELVGVYTGQMSNVLSVQFMACNLLLVT 580 Score = 47.4 bits (111), Expect = 2e-05 Identities = 37/145 (25%), Positives = 57/145 (39%) Frame = +1 Query: 25 TCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDIMRLTQMN 204 T + +L GH V F ++S S D ++R WD+G+ N Sbjct: 333 TEMKILRGHCGPVYSTRFLADSSGLLSCSEDMSIRYWDLGSF----------------TN 376 Query: 205 TDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVDTLR 384 T L+ +GH V P SG+ DR +LW + T + + Sbjct: 377 TVLY-----------QGHAYPVWDLDISPYSLYFASGSHDRTARLWSFDRT--YPLRIYA 423 Query: 385 GHMNNVSCVMFHAKQDIIVSNSEDK 459 GH+ +V CV FH + + + S DK Sbjct: 424 GHLADVDCVKFHPNSNYLATGSTDK 448 Score = 45.4 bits (106), Expect = 8e-05 Identities = 39/169 (23%), Positives = 65/169 (38%), Gaps = 15/169 (8%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIG-----ALRKKTV 165 R W+ S T + GH + V P S S D+T R+W + + Sbjct: 367 RYWDLGSFTNTVLYQGHAYPVWDLDISPYSLYFASGSHDRTARLWSFDRTYPLRIYAGHL 426 Query: 166 SPADDIMRLTQMNTDLFGGVDAVVKY----------VLEGHDRGVNWASFHPTLPLIVSG 315 + D + N G D V+ + GH V +F P + S Sbjct: 427 ADVDCVKFHPNSNYLATGSTDKTVRLWSAQQGNSVRLFTGHRGPVLSLAFSPNGKYLASA 486 Query: 316 ADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSEDKA 462 +D+++KLW + ++ LRGH +N++ + F +I S S D + Sbjct: 487 GEDQRLKLWDLASGTLYK--ELRGHTDNITSLTFSPDSGLIASASMDNS 533 Score = 43.9 bits (102), Expect = 2e-04 Identities = 19/47 (40%), Positives = 27/47 (57%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI 141 ++W+ S T L GH + +F P L+ SAS+D +VRVWDI Sbjct: 493 KLWDLASGTLYKELRGHTDNITSLTFSPDSGLIASASMDNSVRVWDI 539
>YZLL_CAEEL (Q93847) Hypothetical WD-repeat protein K04G11.4| Length = 395 Score = 51.2 bits (121), Expect = 1e-06 Identities = 45/173 (26%), Positives = 71/173 (41%), Gaps = 21/173 (12%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPA-- 174 ++++ S CV L GH +YV C F+P L+ S S D+T+R+W A T+ Sbjct: 173 KVFDVSSGRCVKTLKGHTNYVFCCCFNPSGTLIASGSFDETIRIW--CARNGNTIFSIPG 230 Query: 175 -DDIMRLTQMNTD----LFGGVDAV-----------VKYVLEGHDRGVNWASFHPTLPLI 306 +D + N D G D + VK +++ + F P I Sbjct: 231 HEDPVSSVCFNRDGAYLASGSYDGIVRIWDSTTGTCVKTLIDEEHPPITHVKFSPNGKYI 290 Query: 307 VSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFH---AKQDIIVSNSED 456 ++ + +KLW + + T GH N+ CV + IVS SED Sbjct: 291 LASNLNNTLKLWDYQKLRVLKEYT--GHENSKYCVAANFSVTGGKWIVSGSED 341 Score = 49.3 bits (116), Expect = 5e-06 Identities = 39/150 (26%), Positives = 63/150 (42%), Gaps = 2/150 (1%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHY-VMCASFHPKEDLVVSASLDQTVRVWDIGALRK-KTVSPA 174 RIW+ + TCV L H + F P +++++L+ T+++WD LR K + Sbjct: 257 RIWDSTTGTCVKTLIDEEHPPITHVKFSPNGKYILASNLNNTLKLWDYQKLRVLKEYTGH 316 Query: 175 DDIMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMND 354 ++ N + GG W IVSG++D +V +W + Sbjct: 317 ENSKYCVAANFSVTGG----------------KW---------IVSGSEDHKVYIWNLQT 351 Query: 355 TKAWEVDTLRGHMNNVSCVMFHAKQDIIVS 444 + + TL GH V C H Q+II S Sbjct: 352 REI--LQTLDGHNTAVMCTDCHPGQNIIAS 379 Score = 48.1 bits (113), Expect = 1e-05 Identities = 39/150 (26%), Positives = 63/150 (42%), Gaps = 1/150 (0%) Frame = +1 Query: 13 WQSRTCVAVL-TGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDIMR 189 W + VA + H + F P + S S D ++++W + + +KT Sbjct: 93 WPTYKLVAEIPNAHKKSISGIKFSPDGRYMGSGSADCSIKIWRMDFVYEKT--------- 143 Query: 190 LTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWE 369 L GH G+N S+ LIVS +DD+ VK++ ++ + Sbjct: 144 -------------------LMGHRLGINEFSWSSDSKLIVSCSDDKLVKVFDVSSGRC-- 182 Query: 370 VDTLRGHMNNVSCVMFHAKQDIIVSNSEDK 459 V TL+GH N V C F+ +I S S D+ Sbjct: 183 VKTLKGHTNYVFCCCFNPSGTLIASGSFDE 212 Score = 46.2 bits (108), Expect = 5e-05 Identities = 19/46 (41%), Positives = 29/46 (63%), Gaps = 2/46 (4%) Frame = +1 Query: 4 IWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASL--DQTVRVW 135 IWN Q+R + L GHN VMC HP ++++ SA+L D +++W Sbjct: 346 IWNLQTREILQTLDGHNTAVMCTDCHPGQNIIASAALEPDMRIKIW 391
>SCONB_EMENI (Q00659) Sulfur metabolite repression control protein| Length = 678 Score = 51.2 bits (121), Expect = 1e-06 Identities = 37/138 (26%), Positives = 59/138 (42%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 ++WNW++ C++ TGH V+ H ++ S S+D+TV++W+ K T S Sbjct: 412 KVWNWRTGECISTYTGHRGGVI--GLHFDASILASGSVDKTVKIWNFED--KSTFS---- 463 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTK 360 L GH VN + + S +DD V+LW + DTK Sbjct: 464 ----------------------LRGHTDWVNAVRVDTSSRTVFSASDDCTVRLWDL-DTK 500 Query: 361 AWEVDTLRGHMNNVSCVM 414 + T GH+ V V+ Sbjct: 501 TC-IRTFHGHVGQVQQVV 517 Score = 35.8 bits (81), Expect = 0.061 Identities = 22/71 (30%), Positives = 38/71 (53%), Gaps = 1/71 (1%) Frame = +1 Query: 250 EGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWE-VDTLRGHMNNVSCVMFHAK 426 +GH GV F + + +G+ D +K+W DT+ E + TLRGH + + C+ F Sbjct: 346 KGHTNGVMCLQFEDNI--LATGSYDTTIKIW---DTETGEELRTLRGHESGIRCLQFDDT 400 Query: 427 QDIIVSNSEDK 459 + ++S S D+ Sbjct: 401 K--LISGSMDR 409 Score = 35.4 bits (80), Expect = 0.080 Identities = 23/53 (43%), Positives = 28/53 (52%) Frame = +1 Query: 253 GHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCV 411 GH GV WA TL IVSGA+DR +K+W K T GH V+C+ Sbjct: 607 GHLEGV-WALGADTLR-IVSGAEDRMIKIWDPRTGKCER--TFTGHSGPVTCI 655
>GBLP_MEDSA (O24076) Guanine nucleotide-binding protein beta subunit-like| protein Length = 325 Score = 50.8 bits (120), Expect = 2e-06 Identities = 41/158 (25%), Positives = 66/158 (41%), Gaps = 19/158 (12%) Frame = +1 Query: 40 LTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI--GALRKKTVSPADDIMRL------- 192 LTGH+H+V +S S D +R+WD+ G ++ V D++ + Sbjct: 59 LTGHSHFVQDVVLSSDGQFALSGSWDGELRLWDLNAGTSARRFVGHTKDVLSVAFSIDNR 118 Query: 193 -----TQMNTDLFGGVDAVVKYVLEGHDRGVNWAS---FHPTL--PLIVSGADDRQVKLW 342 ++ T KY ++ D +W S F P+ P IVS + DR VK+W Sbjct: 119 QIVSASRDRTIKLWNTLGECKYTIQDGDAHSDWVSCVRFSPSTPQPTIVSASWDRTVKVW 178 Query: 343 RMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 + + K +TL GH V+ V + S +D Sbjct: 179 NLTNCKL--RNTLAGHSGYVNTVAVSPDGSLCASGGKD 214 Score = 43.1 bits (100), Expect = 4e-04 Identities = 36/139 (25%), Positives = 54/139 (38%), Gaps = 19/139 (13%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPAD- 177 R+W+ + T GH V+ +F +VSAS D+T+++W+ K T+ D Sbjct: 88 RLWDLNAGTSARRFVGHTKDVLSVAFSIDNRQIVSASRDRTIKLWNTLGECKYTIQDGDA 147 Query: 178 -----DIMRL---TQMNTDLFGGVDAVVKY----------VLEGHDRGVNWASFHPTLPL 303 +R T T + D VK L GH VN + P L Sbjct: 148 HSDWVSCVRFSPSTPQPTIVSASWDRTVKVWNLTNCKLRNTLAGHSGYVNTVAVSPDGSL 207 Query: 304 IVSGADDRQVKLWRMNDTK 360 SG D + LW + + K Sbjct: 208 CASGGKDGVILLWDLAEGK 226
>NUDF_EMENI (Q00664) Nuclear migration protein nudF| Length = 444 Score = 50.8 bits (120), Expect = 2e-06 Identities = 45/181 (24%), Positives = 72/181 (39%), Gaps = 38/181 (20%) Frame = +1 Query: 31 VAVLTGHNHYVMCASFHPKEDL-VVSASLDQTVRVWDIGA------LRKKTVSPADDIMR 189 + L+GH+H V F D ++SAS D T+R+WD+ ++ T S D+ Sbjct: 194 IRTLSGHDHSVSSVRFLTSNDNHLISASRDGTLRIWDVSTGFCVKVIKSATESWIRDVSP 253 Query: 190 LTQMNTDLFGGVDAVV----------KYVLEGHDRGVNWASFHP---------------- 291 + GG D + K L GH+ + F P Sbjct: 254 SFDGKWLVSGGRDQAITVWEVSSAEPKAALLGHENFIECCVFAPPASYEHLATLAGLKKP 313 Query: 292 -----TLPLIVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 + + +GA D+ +KLW + + + TL GH N V ++FH + S S+D Sbjct: 314 PPATSSCEFVATGARDKTIKLW---EARGRLIKTLHGHDNWVRGLVFHPGGKYLFSVSDD 370 Query: 457 K 459 K Sbjct: 371 K 371 Score = 48.1 bits (113), Expect = 1e-05 Identities = 42/155 (27%), Positives = 64/155 (41%), Gaps = 6/155 (3%) Frame = +1 Query: 10 NWQSR-TCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWD--IGALRKKTVSPADD 180 NW + + LT H V C +FHP + S S D T+++WD +G + + Sbjct: 99 NWLPKPSSTHTLTSHRDAVTCVAFHPVFTSLASGSEDCTIKIWDWELGEIER-------- 150 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASF--HPTLPLIVSGADDRQVKLWRMND 354 L+GH RGV+ + L+ S + D +KLW + Sbjct: 151 ---------------------TLKGHIRGVSGLDYGGQKGNTLLASCSSDLTIKLWDPSK 189 Query: 355 TKAWEVDTLRGHMNNVSCVMFHAKQD-IIVSNSED 456 A + TL GH ++VS V F D ++S S D Sbjct: 190 DYA-NIRTLSGHDHSVSSVRFLTSNDNHLISASRD 223 Score = 40.0 bits (92), Expect = 0.003 Identities = 34/158 (21%), Positives = 57/158 (36%), Gaps = 22/158 (13%) Frame = +1 Query: 4 IWNWQSRTCVAVLTGHNHYVMCASFHPKE---------------------DLVVSASLDQ 120 +W S A L GH +++ C F P + V + + D+ Sbjct: 271 VWEVSSAEPKAALLGHENFIECCVFAPPASYEHLATLAGLKKPPPATSSCEFVATGARDK 330 Query: 121 TVRVWDIGALRKKTVSPADDIMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLP 300 T+++W+ KT L GHD V FHP Sbjct: 331 TIKLWEARGRLIKT----------------------------LHGHDNWVRGLVFHPGGK 362 Query: 301 LIVSGADDRQVKLWRMNDTKAWEVDTLRG-HMNNVSCV 411 + S +DD+ ++ W ++ + V T+ G H + VSC+ Sbjct: 363 YLFSVSDDKTIRCWDLSQ-EGRLVKTISGAHEHFVSCI 399 Score = 38.5 bits (88), Expect = 0.009 Identities = 19/56 (33%), Positives = 31/56 (55%), Gaps = 1/56 (1%) Frame = +1 Query: 241 YVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVD-TLRGHMNNVS 405 + L H V +FHP + SG++D +K+W D + E++ TL+GH+ VS Sbjct: 108 HTLTSHRDAVTCVAFHPVFTSLASGSEDCTIKIW---DWELGEIERTLKGHIRGVS 160
>PRP46_EMENI (Q5BE22) Pre-mRNA-splicing factor prp46 (Pre-mRNA-processing| protein 46) Length = 452 Score = 50.8 bits (120), Expect = 2e-06 Identities = 41/155 (26%), Positives = 70/155 (45%), Gaps = 15/155 (9%) Frame = +1 Query: 37 VLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI--GALRKKTVSPADDI--MRLTQMN 204 V++GH +V + P + S + D+T+++W++ GALR + + ++ + Sbjct: 138 VISGHLGWVRSLAVEPNNEWFASGAGDRTIKIWNLATGALRLTLTGHISTVRGLAVSPRH 197 Query: 205 TDLFG-GVDAVVK-YVLE---------GHDRGVNWASFHPTLPLIVSGADDRQVKLWRMN 351 LF G D +VK + LE GH GV + HP L L+V+G D ++W M Sbjct: 198 PYLFSCGEDKMVKCWDLETNKVIRHYHGHLSGVYTLALHPRLDLLVTGGRDGVARVWDMR 257 Query: 352 DTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 + L GH V+ V +++ S D Sbjct: 258 TRS--NIHVLSGHTGTVADVQCQEADPQVITGSLD 290 Score = 42.4 bits (98), Expect = 7e-04 Identities = 18/49 (36%), Positives = 30/49 (61%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGA 147 R+W+ ++R+ + VL+GH V + V++ SLD TVR+WD+ A Sbjct: 252 RVWDMRTRSNIHVLSGHTGTVADVQCQEADPQVITGSLDATVRLWDLAA 300 Score = 40.0 bits (92), Expect = 0.003 Identities = 34/150 (22%), Positives = 56/150 (37%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 + W+ ++ + GH V + HP+ DL+V+ D RVWD+ Sbjct: 210 KCWDLETNKVIRHYHGHLSGVYTLALHPRLDLLVTGGRDGVARVWDM------------- 256 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTK 360 T+ N +VL GH V P +++G+ D V+LW + K Sbjct: 257 ---RTRSNI-----------HVLSGHTGTVADVQCQEADPQVITGSLDATVRLWDLAAGK 302 Query: 361 AWEVDTLRGHMNNVSCVMFHAKQDIIVSNS 450 V L H + + H ++ S S Sbjct: 303 TMGV--LTHHKKGIRSLATHPREFTFASAS 330
>GBLP_TOBAC (P49026) Guanine nucleotide-binding protein beta subunit-like| protein Length = 326 Score = 50.4 bits (119), Expect = 2e-06 Identities = 40/154 (25%), Positives = 60/154 (38%), Gaps = 2/154 (1%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 R+W+ Q+ T GH V+ +F +VSAS D+++R+W+ K T+ D Sbjct: 89 RLWDLQAGTTARRFVGHTKDVLSVAFSVDNRQIVSASRDKSIRLWNTLGECKYTIQDGD- 147 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPT--LPLIVSGADDRQVKLWRMND 354 H V+ F P P IVSG+ DR VK+W + + Sbjct: 148 ------------------------SHSDWVSCVRFSPNNLQPTIVSGSWDRTVKIWNLTN 183 Query: 355 TKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 K TL GH V+ + S +D Sbjct: 184 CKLRL--TLAGHTGYVNTPAVSPDGSLCASGGKD 215 Score = 31.6 bits (70), Expect = 1.2 Identities = 15/52 (28%), Positives = 22/52 (42%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRK 156 +IWN + L GH YV + P L S D + +WD+ +K Sbjct: 177 KIWNLTNCKLRLTLAGHTGYVNTPAVSPDGSLCASGGKDGVILLWDLAEGKK 228
>SPG16_HUMAN (Q8N0X2) Sperm-associated antigen 16 protein (PF20 protein homolog)| Length = 631 Score = 50.4 bits (119), Expect = 2e-06 Identities = 33/148 (22%), Positives = 64/148 (43%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 ++W+ + C+ GH+ V ++H + V S+SLD+T ++WD+ + R Sbjct: 419 KLWDLCTGDCILTFEGHSRAVWSCTWHSCGNFVASSSLDKTSKIWDVNSER--------- 469 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTK 360 + L GH VN F P +++ + D+ + +W T Sbjct: 470 ------------------CRCTLYGHTDSVNSIEFFPFSNTLLTSSADKTLSIWDAR-TG 510 Query: 361 AWEVDTLRGHMNNVSCVMFHAKQDIIVS 444 E +L GHM++++ +F + +I S Sbjct: 511 ICE-QSLYGHMHSINDAIFDPRGHMIAS 537 Score = 50.4 bits (119), Expect = 2e-06 Identities = 37/149 (24%), Positives = 65/149 (43%), Gaps = 2/149 (1%) Frame = +1 Query: 28 CVAVLTGHNH--YVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDIMRLTQM 201 C +LTG H ++ FHP D + ++S D TV++WD+ D I+ Sbjct: 384 CNVLLTGFGHTDWLSDCCFHPSGDKLATSSGDTTVKLWDL--------CTGDCIL----- 430 Query: 202 NTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVDTL 381 EGH R V ++H + S + D+ K+W +N + TL Sbjct: 431 --------------TFEGHSRAVWSCTWHSCGNFVASSSLDKTSKIWDVNSERC--RCTL 474 Query: 382 RGHMNNVSCVMFHAKQDIIVSNSEDKAFA 468 GH ++V+ + F + ++++S DK + Sbjct: 475 YGHTDSVNSIEFFPFSNTLLTSSADKTLS 503 Score = 37.7 bits (86), Expect = 0.016 Identities = 35/137 (25%), Positives = 53/137 (38%) Frame = +1 Query: 49 HNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDIMRLTQMNTDLFGGVD 228 H V C S P +D++VS D R+W + L K V L G Sbjct: 351 HELPVSCVSMQPHKDILVSCGED---RLWKVLGLPKCNV---------------LLTGF- 391 Query: 229 AVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSC 408 GH ++ FHP+ + + + D VKLW + + T GH V Sbjct: 392 --------GHTDWLSDCCFHPSGDKLATSSGDTTVKLWDLCTGDC--ILTFEGHSRAVWS 441 Query: 409 VMFHAKQDIIVSNSEDK 459 +H+ + + S+S DK Sbjct: 442 CTWHSCGNFVASSSLDK 458 Score = 34.7 bits (78), Expect = 0.14 Identities = 34/151 (22%), Positives = 56/151 (37%) Frame = +1 Query: 4 IWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDI 183 IW+ ++ C L GH H + A F P+ ++ S ++WD L Sbjct: 504 IWDARTGICEQSLYGHMHSINDAIFDPRGHMIASCDACGVTKLWDFRKL----------- 552 Query: 184 MRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKA 363 L ++ D+ V + G R + AS + + L+ D K+ Sbjct: 553 --LPIVSIDIGPSPGNEVNFDSSG--RVLAQASGNGVIHLL---------------DLKS 593 Query: 364 WEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 E+ L GH N V+F +I+ S D Sbjct: 594 GEIHKLMGHENEAHTVVFSHDGEILFSGGSD 624
>GBLP_SOYBN (Q39836) Guanine nucleotide-binding protein beta subunit-like| protein Length = 325 Score = 50.4 bits (119), Expect = 2e-06 Identities = 41/158 (25%), Positives = 66/158 (41%), Gaps = 19/158 (12%) Frame = +1 Query: 40 LTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI--GALRKKTVSPADDIMRL------- 192 LTGH+H+V +S S D +R+WD+ G ++ V D++ + Sbjct: 59 LTGHSHFVQDVVLSSDGQFALSGSWDGELRLWDLAAGTSARRFVGHTKDVLSVAFSIDNR 118 Query: 193 -----TQMNTDLFGGVDAVVKYVLEGHDRGVNWAS---FHPTL--PLIVSGADDRQVKLW 342 ++ T KY ++ D +W S F P+ P IVS + DR VK+W Sbjct: 119 QIVSASRDRTIKLWNTLGECKYTIQDGDAHSDWVSCVRFSPSTLQPTIVSASWDRTVKVW 178 Query: 343 RMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 + + K +TL GH V+ V + S +D Sbjct: 179 NLTNCKL--RNTLAGHNGYVNTVAVSPDGSLCASGGKD 214 Score = 32.7 bits (73), Expect = 0.52 Identities = 14/47 (29%), Positives = 21/47 (44%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI 141 ++WN + L GHN YV + P L S D + +WD+ Sbjct: 176 KVWNLTNCKLRNTLAGHNGYVNTVAVSPDGSLCASGGKDGVILLWDL 222
>APAF_BRARE (Q9I9H8) Apoptotic protease-activating factor 1 (Apaf-1)| Length = 1261 Score = 50.4 bits (119), Expect = 2e-06 Identities = 44/165 (26%), Positives = 76/165 (46%), Gaps = 14/165 (8%) Frame = +1 Query: 4 IWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIG--------ALRKK 159 +WN++S A +GH +V C F P L++S+S DQT+R+W+ AL++ Sbjct: 868 LWNFESSKKKAECSGHLSWVHCVQFSPDGSLLLSSSDDQTIRLWETDRVHTSSAVALKRD 927 Query: 160 T--VSPADDIMRLTQMNTD----LFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGAD 321 T +S D + +++ L G AVV E R + + + G++ Sbjct: 928 TDVLSSHSDATIIAPDSSNRLQVLSGSTGAVVLESEELSSR-IRCSCISRNAAFVALGSE 986 Query: 322 DRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 D V++ + +KA L GH V F +I++++SED Sbjct: 987 DGTVQVIEVPSSKA--SVKLSGHTKTVHHCQFTDDCEILITSSED 1029 Score = 44.3 bits (103), Expect = 2e-04 Identities = 36/138 (26%), Positives = 60/138 (43%), Gaps = 20/138 (14%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGH-----NHYVMCASFHPKEDLVVSASLDQTVRVWDI-------- 141 R+W W++ C+ VL GH +++ +S P + S S D TV+VWD+ Sbjct: 1033 RVWKWRTGECM-VLQGHMEPVRKFHLLSSSSSPH---LFSWSFDGTVKVWDLTRGQMLQD 1088 Query: 142 -----GALRKKTVSPADDIMRLTQMN--TDLFGGVDAVVKYVLEGHDRGVNWASFHPTLP 300 GA+ VS + T N ++ + ++LEGH V F Sbjct: 1089 LVCHEGAVLSCDVSSDGRLFATTSANRTAKVWSSASWKMLFLLEGHKDCVRSCRFSWDNK 1148 Query: 301 LIVSGADDRQVKLWRMND 354 + +G D+ +++LW M D Sbjct: 1149 RLATGDDNGEIRLWSMLD 1166 Score = 35.8 bits (81), Expect = 0.061 Identities = 27/143 (18%), Positives = 57/143 (39%), Gaps = 20/143 (13%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI--GALRKKTVSPA 174 R++ S + L H V+C +F P + + + + D+ V++W++ G L ++ Sbjct: 642 RVFKSTSGEKLLELQAHEEDVLCCAFSPDDRHIATCASDRKVKLWNVERGVLIREFEVEH 701 Query: 175 DDIMRLTQM------------------NTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLP 300 ++ + Q NT L+ + + GH VN F P Sbjct: 702 EEQINHCQFTNTGRRVLLATCSNDKFTNTRLWNPNKKTSQNTMFGHMEPVNHCCFSPNDL 761 Query: 301 LIVSGADDRQVKLWRMNDTKAWE 369 + + + D +KL+ ++ W+ Sbjct: 762 YLATSSSDGSLKLFEVSSANEWK 784 Score = 33.5 bits (75), Expect = 0.30 Identities = 33/178 (18%), Positives = 74/178 (41%), Gaps = 25/178 (14%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRK-KTVS--- 168 R+WN +T + GH V F P + + ++S D +++++++ + + K++ Sbjct: 731 RLWNPNKKTSQNTMFGHMEPVNHCCFSPNDLYLATSSSDGSLKLFEVSSANEWKSIDVDS 790 Query: 169 --PADD-----IMRLTQMNTD----LFGGVDAVVKYVLEGHD----------RGVNWASF 285 P D +++ + + D + + V + +E D + + Sbjct: 791 FFPESDEEIKAMVKCSTWSADGSQIICAARNTVFVFDVETSDLLLKLKTSRLSTIQFCHA 850 Query: 286 HPTLPLIVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSEDK 459 P L+ V+LW +K + GH++ V CV F +++S+S+D+ Sbjct: 851 CPNSSLLAVALSHYTVELWNFESSK--KKAECSGHLSWVHCVQFSPDGSLLLSSSDDQ 906 Score = 29.6 bits (65), Expect = 4.4 Identities = 22/88 (25%), Positives = 39/88 (44%) Frame = +1 Query: 190 LTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWE 369 L+ +L+ + K GH V+ F P L++S +DD+ ++LW Sbjct: 861 LSHYTVELWNFESSKKKAECSGHLSWVHCVQFSPDGSLLLSSSDDQTIRLW--------- 911 Query: 370 VDTLRGHMNNVSCVMFHAKQDIIVSNSE 453 +T R H + S V D++ S+S+ Sbjct: 912 -ETDRVHTS--SAVALKRDTDVLSSHSD 936
>GBLP_HYDAT (Q25189) Guanine nucleotide-binding protein beta subunit-like| protein (Receptor of activated protein kinase C) (RACK) Length = 317 Score = 50.4 bits (119), Expect = 2e-06 Identities = 36/125 (28%), Positives = 55/125 (44%), Gaps = 18/125 (14%) Frame = +1 Query: 40 LTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI--GALRKKTVSPADDIMRL------- 192 LTGHNH+V +S S D+T+R+WD+ G K+ V D++ + Sbjct: 59 LTGHNHFVSDVVLSSDGQFALSCSWDKTLRLWDLNQGITTKQFVGHTKDVLSVAFSADNR 118 Query: 193 -----TQMNTDLFGGVDAVVKYVL--EGHDRGVNWASFHPTL--PLIVSGADDRQVKLWR 345 ++ NT KY + E H V+ F P P+IVS D+ VK+W Sbjct: 119 QIVSGSRDNTIKLWNTLGQCKYTIQDESHSEWVSCVRFSPNTQNPIIVSCGWDKMVKVWN 178 Query: 346 MNDTK 360 + + K Sbjct: 179 LTNCK 183 Score = 40.0 bits (92), Expect = 0.003 Identities = 43/172 (25%), Positives = 69/172 (40%), Gaps = 24/172 (13%) Frame = +1 Query: 16 QSRTCVAVLTGHNHYVMCASFHPKE-DLVVSASLDQTVRVWDIG-------ALRKKTVSP 171 + T L GHN +V + P+ DL++SAS D+T+ W + KK ++ Sbjct: 2 EQMTLRGTLKGHNGWVTQIATTPQNPDLILSASRDKTLIQWQLTRDDQTNYGFPKKCLTG 61 Query: 172 ADDIMRLTQMNTD--------------LFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIV 309 + + +++D L+ + GH + V +F IV Sbjct: 62 HNHFVSDVVLSSDGQFALSCSWDKTLRLWDLNQGITTKQFVGHTKDVLSVAFSADNRQIV 121 Query: 310 SGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMF--HAKQDIIVSNSEDK 459 SG+ D +KLW + + H VSCV F + + IIVS DK Sbjct: 122 SGSRDNTIKLWNTLGQCKYTIQD-ESHSEWVSCVRFSPNTQNPIIVSCGWDK 172
>APAF_RAT (Q9EPV5) Apoptotic protease-activating factor 1 (Apaf-1)| Length = 1249 Score = 50.1 bits (118), Expect = 3e-06 Identities = 43/181 (23%), Positives = 76/181 (41%), Gaps = 28/181 (15%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI-GALRKKTVS--- 168 ++W+ + C + GH + V F P ++L+ S S D T+++WD+ A KK+++ Sbjct: 726 KLWDLNQKECRNTMFGHTNSVTHCRFSPDDELLASCSADGTLKLWDVRSANEKKSINVKR 785 Query: 169 -------PADD---IMRLTQMNTDLFGGVDAVVKYVL--------------EGHDRGVNW 276 P +D I++ + D + A VL GH + + Sbjct: 786 FFLSSEDPPEDVEVIVKCCSWSADGDRIIVAAKNKVLLLDIHTSGLLTEIHTGHHSTIQY 845 Query: 277 ASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 F P L V V+LW ++ +V RGH++ V VMF ++ S+D Sbjct: 846 CDFSPYDHLAVIALSQYCVELWNIDSRV--KVADCRGHLSWVHGVMFSPDGSSFLTASDD 903 Query: 457 K 459 + Sbjct: 904 Q 904 Score = 49.3 bits (116), Expect = 5e-06 Identities = 42/164 (25%), Positives = 69/164 (42%), Gaps = 13/164 (7%) Frame = +1 Query: 4 IWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKT------- 162 +WN SR VA GH +V F P ++AS DQT+RVW+ + K + Sbjct: 866 LWNIDSRVKVADCRGHLSWVHGVMFSPDGSSFLTASDDQTIRVWETRKVCKNSAIVLKQE 925 Query: 163 ---VSPADDIMRLTQMN---TDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADD 324 V +++M L N L G + Y+ E V+ P L + G ++ Sbjct: 926 IDVVFQENEMMVLAVDNIRGLQLIAGKTGQIDYLPEAQ---VSCCCLSPHLEYVAFGDEE 982 Query: 325 RQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 +K+ + + + + GH V + F A ++S+SED Sbjct: 983 GAIKIIELPNNRVFSSGI--GHKKAVRHIQFTADGKTLISSSED 1024 Score = 44.7 bits (104), Expect = 1e-04 Identities = 31/141 (21%), Positives = 57/141 (40%), Gaps = 2/141 (1%) Frame = +1 Query: 40 LTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDIMRLTQMNTDLFG 219 + H V+C +F + + + S+D+ V++WD G Sbjct: 653 IKAHEDEVLCCAFSSDDSYIATCSVDKKVKIWDSGT------------------------ 688 Query: 220 GVDAVVKYVLEGHDRGVNWASF--HPTLPLIVSGADDRQVKLWRMNDTKAWEVDTLRGHM 393 + + E H VN F L+ +G++D +KLW +N + +T+ GH Sbjct: 689 ---GKLVHTYEEHSEQVNCCHFTNKSNHLLLATGSNDSFLKLWDLNQKEC--RNTMFGHT 743 Query: 394 NNVSCVMFHAKQDIIVSNSED 456 N+V+ F +++ S S D Sbjct: 744 NSVTHCRFSPDDELLASCSAD 764 Score = 30.8 bits (68), Expect = 2.0 Identities = 12/47 (25%), Positives = 27/47 (57%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI 141 +IW+++ + + L GHN V C++F L+ + + +R+W++ Sbjct: 1110 KIWSFELPSPLHELKGHNSCVRCSAFSLDGILLATGDDNGEIRIWNV 1156
>APAF_MOUSE (O88879) Apoptotic protease-activating factor 1 (Apaf-1)| Length = 1249 Score = 50.1 bits (118), Expect = 3e-06 Identities = 43/164 (26%), Positives = 68/164 (41%), Gaps = 13/164 (7%) Frame = +1 Query: 4 IWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKT------- 162 +WN SR VA GH +V F P ++AS DQT+RVW+ + K + Sbjct: 866 LWNIDSRLKVADCRGHLSWVHGVMFSPDGSSFLTASDDQTIRVWETKKVCKNSAIVLKQE 925 Query: 163 ---VSPADDIMRLTQMN---TDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADD 324 V ++ M L N L G + Y+ E V+ P L + G +D Sbjct: 926 IDVVFQENETMVLAVDNIRGLQLIAGKTGQIDYLPEAQ---VSCCCLSPHLEYVAFGDED 982 Query: 325 RQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 +K+ + + + + GH V + F A ++S+SED Sbjct: 983 GAIKIIELPNNRVFSSGV--GHKKAVRHIQFTADGKTLISSSED 1024 Score = 49.7 bits (117), Expect = 4e-06 Identities = 43/181 (23%), Positives = 76/181 (41%), Gaps = 28/181 (15%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI-GALRKKTVS--- 168 ++W+ + C + GH + V F P ++L+ S S D T+R+WD+ A +K+++ Sbjct: 726 KLWDLNQKECRNTMFGHTNSVNHCRFSPDDELLASCSADGTLRLWDVRSANERKSINVKR 785 Query: 169 -------PADD---IMRLTQMNTD-------------LFG-GVDAVVKYVLEGHDRGVNW 276 P +D I++ + D LF ++ + GH + + Sbjct: 786 FFLSSEDPPEDVEVIVKCCSWSADGDKIIVAAKNKVLLFDIHTSGLLAEIHTGHHSTIQY 845 Query: 277 ASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 F P L V V+LW N +V RGH++ V VMF ++ S+D Sbjct: 846 CDFSPYDHLAVIALSQYCVELW--NIDSRLKVADCRGHLSWVHGVMFSPDGSSFLTASDD 903 Query: 457 K 459 + Sbjct: 904 Q 904 Score = 40.8 bits (94), Expect = 0.002 Identities = 32/141 (22%), Positives = 58/141 (41%), Gaps = 2/141 (1%) Frame = +1 Query: 40 LTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDIMRLTQMNTDLFG 219 + H V+C +F + + + S D+ V++WD + K V D+ Sbjct: 653 IKAHEDEVLCCAFSSDDSYIATCSADKKVKIWD--SATGKLVHTYDE------------- 697 Query: 220 GVDAVVKYVLEGHDRGVNWASFHPTLP--LIVSGADDRQVKLWRMNDTKAWEVDTLRGHM 393 H VN F + L+ +G++D +KLW +N + +T+ GH Sbjct: 698 ------------HSEQVNCCHFTNSSNHLLLATGSNDFFLKLWDLNQKEC--RNTMFGHT 743 Query: 394 NNVSCVMFHAKQDIIVSNSED 456 N+V+ F +++ S S D Sbjct: 744 NSVNHCRFSPDDELLASCSAD 764 Score = 34.3 bits (77), Expect = 0.18 Identities = 30/134 (22%), Positives = 63/134 (47%), Gaps = 16/134 (11%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDL-VVSASLDQTVRVWDI--GALRKK---- 159 ++WNWQ+ V L H V F +D ++S S D TV+VW++ G + + Sbjct: 1028 QVWNWQTGDYV-FLQAHQETVK--DFRLLQDSRLLSWSFDGTVKVWNVITGRIERDFTCH 1084 Query: 160 -----TVSPADDIMRLTQMNTDLFGGVDAV----VKYVLEGHDRGVNWASFHPTLPLIVS 312 + + + D + + + D + + + L+GH+ V ++F L+ + Sbjct: 1085 QGTVLSCAISSDATKFSSTSADKTAKIWSFDLLSPLHELKGHNGCVRCSAFSLDGILLAT 1144 Query: 313 GADDRQVKLWRMND 354 G D+ ++++W ++D Sbjct: 1145 GDDNGEIRIWNVSD 1158 Score = 29.6 bits (65), Expect = 4.4 Identities = 12/47 (25%), Positives = 26/47 (55%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI 141 +IW++ + + L GHN V C++F L+ + + +R+W++ Sbjct: 1110 KIWSFDLLSPLHELKGHNGCVRCSAFSLDGILLATGDDNGEIRIWNV 1156
>GRWD1_MOUSE (Q810D6) Glutamate-rich WD repeat-containing protein 1 (Protein| A301) Length = 446 Score = 50.1 bits (118), Expect = 3e-06 Identities = 42/150 (28%), Positives = 60/150 (40%), Gaps = 2/150 (1%) Frame = +1 Query: 7 WNWQSRTCVAVLTGHNHYVMCASFHPKEDLV-VSASLDQTVRVWDIGALRKKTVSPADDI 183 WN R V GH V + P ED V S S D ++R+WDI A K Sbjct: 250 WNVDQRPFV----GHTRSVEDLQWSPTEDTVFASCSADASIRIWDIRAAPGK-------- 297 Query: 184 MRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKA 363 A + HD VN S+ P ++SG DD +K+W + K+ Sbjct: 298 ---------------ACMLTTATAHDGDVNVISWSRREPFLLSGGDDGALKVWDLRQFKS 342 Query: 364 WE-VDTLRGHMNNVSCVMFHAKQDIIVSNS 450 V T + HM V+ V +H + + + S Sbjct: 343 GSPVATFKQHMAPVTSVEWHPQDSGVFAAS 372
>TAF5_SCHPO (O13282) Transcription initiation factor TFIID subunit 5| (Transcription initiation factor TFIID 72 kDa subunit) (TAFII-72) Length = 643 Score = 50.1 bits (118), Expect = 3e-06 Identities = 35/152 (23%), Positives = 60/152 (39%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 ++W+ + V GH V C +FHP V++ S D+T R+WD+ R +V Sbjct: 446 QLWSCDHIYPLRVFAGHLSDVDCVTFHPNSAYVLTGSSDKTCRLWDVH--RGHSVR---- 499 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTK 360 V GH + V + P + S + + LW + + Sbjct: 500 ---------------------VFNGHTQPVTAVAIAPDGHTMASADSEGLIHLWDIGTGR 538 Query: 361 AWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 + T+RGH N+ + F + ++VS D Sbjct: 539 --RIKTMRGHRGNIYSLSFSRESTVLVSGGSD 568 Score = 46.6 bits (109), Expect = 3e-05 Identities = 39/174 (22%), Positives = 70/174 (40%), Gaps = 30/174 (17%) Frame = +1 Query: 28 CVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKK-----TVSPADDIMRL 192 C+ N+ + CA F P ++ + +R+W I A +K +V +D +RL Sbjct: 316 CMYTFHHTNNNMNCAEFSPDSTMIACGFQESYIRLWSIKADKKSLPKSTSVEDSDGSVRL 375 Query: 193 TQMNTDLFG----------------------GVD---AVVKYVLEGHDRGVNWASFHPTL 297 + ++G VD A+V Y +GH V +F P Sbjct: 376 LSHSGPVYGTTFSPDNKYLLSCSEDASARLWSVDTKTALVAY--KGHTGPVWDVAFGPFG 433 Query: 298 PLIVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSEDK 459 + + D+ +LW + + + GH+++V CV FH +++ S DK Sbjct: 434 HYFATASHDQTAQLWSCDHI--YPLRVFAGHLSDVDCVTFHPNSAYVLTGSSDK 485 Score = 31.2 bits (69), Expect = 1.5 Identities = 13/46 (28%), Positives = 23/46 (50%) Frame = +1 Query: 4 IWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI 141 +W+ + + + GH + SF + ++VS D TVR WD+ Sbjct: 531 LWDIGTGRRIKTMRGHRGNIYSLSFSRESTVLVSGGSDCTVRAWDV 576
>GBB_ARATH (P49177) Guanine nucleotide-binding protein beta subunit| (transducin) (AGB1) Length = 377 Score = 49.7 bits (117), Expect = 4e-06 Identities = 41/131 (31%), Positives = 58/131 (44%), Gaps = 4/131 (3%) Frame = +1 Query: 37 VLTGHNHYVMCASFHPKEDL-VVSASLDQTVRVWDIGALRKKTVSPADDIMRLTQMNTDL 213 +LTGH YV C + P ED ++++S DQT +WD+ T + T + Sbjct: 151 MLTGHRGYVSCCQYVPNEDAHLITSSGDQTCILWDV----------------TTGLKTSV 194 Query: 214 FGGVDAVVKYVLEGHDRGVNWASFHPTLP-LIVSGADDRQVKLWRMNDTKAWE--VDTLR 384 FGG GH V S + P +SG+ D +LW DT+A V T Sbjct: 195 FGG------EFQSGHTADVLSVSISGSNPNWFISGSCDSTARLW---DTRAASRAVRTFH 245 Query: 385 GHMNNVSCVMF 417 GH +V+ V F Sbjct: 246 GHEGDVNTVKF 256
>PRP46_ASPFU (Q4WT34) Pre-mRNA-splicing factor prp46 (Pre-mRNA-processing| protein 46) Length = 453 Score = 49.7 bits (117), Expect = 4e-06 Identities = 41/155 (26%), Positives = 70/155 (45%), Gaps = 15/155 (9%) Frame = +1 Query: 37 VLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI--GALRKKTVSPADDI--MRLTQMN 204 V++GH +V + P + S + D+T+++W++ GALR + + ++ + Sbjct: 139 VISGHLGWVRSLAVEPNNEWFASGAGDRTIKIWNLATGALRLTLTGHISTVRGLAVSPRH 198 Query: 205 TDLFG-GVDAVVK-YVLE---------GHDRGVNWASFHPTLPLIVSGADDRQVKLWRMN 351 LF G D +VK + LE GH GV + HP L L+V+G D ++W M Sbjct: 199 PYLFSCGEDKMVKCWDLETNKVIRHYHGHLSGVYTLALHPRLDLLVTGGRDGVARVWDMR 258 Query: 352 DTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 + L GH V+ + I++ S D Sbjct: 259 TRS--NIHVLSGHKGTVADLKCQEADPQIITGSLD 291 Score = 41.6 bits (96), Expect = 0.001 Identities = 17/49 (34%), Positives = 30/49 (61%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGA 147 R+W+ ++R+ + VL+GH V + +++ SLD TVR+WD+ A Sbjct: 253 RVWDMRTRSNIHVLSGHKGTVADLKCQEADPQIITGSLDATVRLWDLAA 301 Score = 40.4 bits (93), Expect = 0.002 Identities = 36/150 (24%), Positives = 56/150 (37%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 + W+ ++ + GH V + HP+ DL+V+ D RVWD+ Sbjct: 211 KCWDLETNKVIRHYHGHLSGVYTLALHPRLDLLVTGGRDGVARVWDM------------- 257 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTK 360 T+ N +VL GH V P I++G+ D V+LW + K Sbjct: 258 ---RTRSNI-----------HVLSGHKGTVADLKCQEADPQIITGSLDATVRLWDLAAGK 303 Query: 361 AWEVDTLRGHMNNVSCVMFHAKQDIIVSNS 450 V L H V + H ++ S S Sbjct: 304 TMGV--LTHHKKGVRNLAIHPREFTFASAS 331
>WDR37_MOUSE (Q8CBE3) WD-repeat protein 37| Length = 496 Score = 49.3 bits (116), Expect = 5e-06 Identities = 42/169 (24%), Positives = 72/169 (42%), Gaps = 15/169 (8%) Frame = +1 Query: 4 IWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVW---------DIGALRK 156 +W+ ++ C+ GH V FHP E L ++AS DQT +W A Sbjct: 183 LWSIETGKCLVKYAGHVGSVNSIKFHPSEQLALTASGDQTAHIWRYVVQLPTPQPVADTS 242 Query: 157 KTVSPADDIMRLTQMNTDLFGGVDAVVKYV------LEGHDRGVNWASFHPTLPLIVSGA 318 + +S D+I + D+ G V + V L+ H V A + +V+ + Sbjct: 243 QQISGEDEIECSDKDEPDIDGDVSSDCPTVRVPLTSLKSHQGVVIAADWLVGGKQVVTAS 302 Query: 319 DDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSEDKAF 465 DR L+ + ++ V +L GH ++ H Q ++V++S D F Sbjct: 303 WDRTANLYDVETSEL--VHSLTGHDQELTHCCTHPTQRLVVTSSRDTTF 349 Score = 47.8 bits (112), Expect = 2e-05 Identities = 35/146 (23%), Positives = 60/146 (41%) Frame = +1 Query: 22 RTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDIMRLTQM 201 R + L H V+ A + VV+AS D+T ++D+ Sbjct: 273 RVPLTSLKSHQGVVIAADWLVGGKQVVTASWDRTANLYDVET------------------ 314 Query: 202 NTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVDTL 381 + + + L GHD+ + HPT L+V+ + D +LW D V+ Sbjct: 315 ---------SELVHSLTGHDQELTHCCTHPTQRLVVTSSRDTTFRLWDFRDPSIHSVNVF 365 Query: 382 RGHMNNVSCVMFHAKQDIIVSNSEDK 459 +GH + V+ +F D +VS S+D+ Sbjct: 366 QGHTDTVTSAVF-TVGDNVVSGSDDR 390 Score = 43.1 bits (100), Expect = 4e-04 Identities = 32/120 (26%), Positives = 54/120 (45%) Frame = +1 Query: 4 IWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDI 183 +++ ++ V LTGH+ + HP + LVV++S D T R+WD R ++ + Sbjct: 309 LYDVETSELVHSLTGHDQELTHCCTHPTQRLVVTSSRDTTFRLWD---FRDPSIHSVN-- 363 Query: 184 MRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKA 363 V +GH V A F +VSG+DDR VK+W + + ++ Sbjct: 364 --------------------VFQGHTDTVTSAVF-TVGDNVVSGSDDRTVKVWDLKNMRS 402
>PRP46_CANAL (Q5A7Q3) Pre-mRNA-splicing factor PRP46 (Pre-mRNA-processing| protein 46) Length = 389 Score = 49.3 bits (116), Expect = 5e-06 Identities = 36/152 (23%), Positives = 65/152 (42%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 +IW++++ + AVLTGH + + + S D+++R WD Sbjct: 111 KIWDFENNSLKAVLTGHVLGIRSLCISKRHPYLFSGGEDKSLRCWD-------------- 156 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTK 360 L + N+D + + GH GV HP L ++ SG D V++W + Sbjct: 157 ---LERSNSDAGCQIRS-----YHGHLGGVYSIGLHPELDVLFSGGKDCVVRVWDIRSRV 208 Query: 361 AWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 E TL GH N+++ + ++++S D Sbjct: 209 --EAMTLLGHTNDITSIETDYNDPQVITSSMD 238 Score = 40.4 bits (93), Expect = 0.002 Identities = 25/114 (21%), Positives = 46/114 (40%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 R+W+ +SR L GH + + + V+++S+D T+R+WD Sbjct: 200 RVWDIRSRVEAMTLLGHTNDITSIETDYNDPQVITSSMDGTIRLWD-------------- 245 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLW 342 L + T+L ++ H + + HP VSG + ++K W Sbjct: 246 ---LRKSKTEL----------LITNHSKSIRSMKSHPKEATFVSGDSNGEIKQW 286
>PRP46_KLULA (Q6CKE8) Pre-mRNA-splicing factor PRP46 (Pre-mRNA-processing| protein 46) Length = 434 Score = 49.3 bits (116), Expect = 5e-06 Identities = 40/161 (24%), Positives = 63/161 (39%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 + W+ + T + GH V HP D++ +A D VR+WDI + + Sbjct: 190 KCWDLERNTAIRDFHGHLSGVHTVDVHPSLDIIATAGRDAVVRLWDIRS--------RSE 241 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTK 360 IM VL GH +N P P I+S + D V+LW + K Sbjct: 242 IM-------------------VLPGHKSPINKVKCLPVDPQIISCSGDATVRLWDIIAGK 282 Query: 361 AWEVDTLRGHMNNVSCVMFHAKQDIIVSNSEDKAFASGMPQ 483 A +V L H N+ + H + S S + + +P+ Sbjct: 283 ASKV--LTHHSRNIRDLTLHPAEFSFASVSTNDVRSWKLPE 321
>PRP19_RAT (Q9JMJ4) Pre-mRNA-splicing factor 19 (PRP19/PSO4 homolog) (Neuronal| differentiation-related gene protein) Length = 504 Score = 49.3 bits (116), Expect = 5e-06 Identities = 37/171 (21%), Positives = 70/171 (40%), Gaps = 18/171 (10%) Frame = +1 Query: 4 IWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI-------------G 144 +++ + +A L GH V FHP ++LV SAS D T+R+W + Sbjct: 248 VFDKSTEQILATLKGHTKKVTSVVFHPSQELVFSASPDATIRIWSVPNTSCVQVVRAHES 307 Query: 145 ALRKKTVSPADDIMRLTQMNTDLFGGVD-----AVVKYVLEGHDRGVNWASFHPTLPLIV 309 A+ ++ D + L+ + + D + K E + A FHP + Sbjct: 308 AVTGLSLHATGDYL-LSSSDDQYWAFSDIQTGRVLTKVTDETSGCSLTCAQFHPDGLIFG 366 Query: 310 SGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSEDKA 462 +G D Q+K+W + + V GH ++ + F + + ++D + Sbjct: 367 TGTMDSQIKIWDLKERT--NVANFPGHSGPITSIAFSENGYYLATAADDSS 415 Score = 48.5 bits (114), Expect = 9e-06 Identities = 23/74 (31%), Positives = 43/74 (58%) Frame = +1 Query: 247 LEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAK 426 L+GH + V FHP+ L+ S + D +++W + +T V +R H + V+ + HA Sbjct: 260 LKGHTKKVTSVVFHPSQELVFSASPDATIRIWSVPNTSC--VQVVRAHESAVTGLSLHAT 317 Query: 427 QDIIVSNSEDKAFA 468 D ++S+S+D+ +A Sbjct: 318 GDYLLSSSDDQYWA 331 Score = 34.3 bits (77), Expect = 0.18 Identities = 18/73 (24%), Positives = 35/73 (47%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 +IW+ + RT VA GH+ + +F + +A+ D +V++WD+ L+ D+ Sbjct: 375 KIWDLKERTNVANFPGHSGPITSIAFSENGYYLATAADDSSVKLWDLRKLKNFKTLQLDN 434 Query: 181 IMRLTQMNTDLFG 219 + + D G Sbjct: 435 NFEVKSLIFDQSG 447 Score = 32.3 bits (72), Expect = 0.67 Identities = 16/51 (31%), Positives = 30/51 (58%) Frame = +1 Query: 304 IVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 I++G D+ V ++ + + + TL+GH V+ V+FH Q+++ S S D Sbjct: 237 ILTGGADKNVVVFDKSTEQI--LATLKGHTKKVTSVVFHPSQELVFSASPD 285
>PRP19_MOUSE (Q99KP6) Pre-mRNA-splicing factor 19 (PRP19/PSO4 homolog) (Nuclear| matrix protein 200) (Nuclear matrix protein SNEV) Length = 504 Score = 49.3 bits (116), Expect = 5e-06 Identities = 37/171 (21%), Positives = 70/171 (40%), Gaps = 18/171 (10%) Frame = +1 Query: 4 IWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI-------------G 144 +++ + +A L GH V FHP ++LV SAS D T+R+W + Sbjct: 248 VFDKSTEQILATLKGHTKKVTSVVFHPSQELVFSASPDATIRIWSVPNTSCVQVVRAHES 307 Query: 145 ALRKKTVSPADDIMRLTQMNTDLFGGVD-----AVVKYVLEGHDRGVNWASFHPTLPLIV 309 A+ ++ D + L+ + + D + K E + A FHP + Sbjct: 308 AVTGLSLHATGDYL-LSSSDDQYWAFSDIQTGRVLTKVTDETSGCSLTCAQFHPDGLIFG 366 Query: 310 SGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSEDKA 462 +G D Q+K+W + + V GH ++ + F + + ++D + Sbjct: 367 TGTMDSQIKIWDLKERT--NVANFPGHSGPITSIAFSENGYYLATAADDSS 415 Score = 48.5 bits (114), Expect = 9e-06 Identities = 23/74 (31%), Positives = 43/74 (58%) Frame = +1 Query: 247 LEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAK 426 L+GH + V FHP+ L+ S + D +++W + +T V +R H + V+ + HA Sbjct: 260 LKGHTKKVTSVVFHPSQELVFSASPDATIRIWSVPNTSC--VQVVRAHESAVTGLSLHAT 317 Query: 427 QDIIVSNSEDKAFA 468 D ++S+S+D+ +A Sbjct: 318 GDYLLSSSDDQYWA 331 Score = 34.3 bits (77), Expect = 0.18 Identities = 18/73 (24%), Positives = 35/73 (47%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 +IW+ + RT VA GH+ + +F + +A+ D +V++WD+ L+ D+ Sbjct: 375 KIWDLKERTNVANFPGHSGPITSIAFSENGYYLATAADDSSVKLWDLRKLKNFKTLQLDN 434 Query: 181 IMRLTQMNTDLFG 219 + + D G Sbjct: 435 NFEVKSLIFDQSG 447 Score = 32.3 bits (72), Expect = 0.67 Identities = 16/51 (31%), Positives = 30/51 (58%) Frame = +1 Query: 304 IVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 I++G D+ V ++ + + + TL+GH V+ V+FH Q+++ S S D Sbjct: 237 ILTGGADKNVVVFDKSTEQI--LATLKGHTKKVTSVVFHPSQELVFSASPD 285
>PWP2_YEAST (P25635) Periodic tryptophan protein 2 (U3 small nucleolar| RNA-associated protein 1) (U3 snoRNA-associated protein 1) Length = 923 Score = 49.3 bits (116), Expect = 5e-06 Identities = 36/154 (23%), Positives = 64/154 (41%), Gaps = 1/154 (0%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 ++W+ S C+A H V F + ++ S+SLD TVR WD+ Sbjct: 370 KVWDITSGFCLATFEEHTSSVTAVQFAKRGQVMFSSSLDGTVRAWDL------------- 416 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGA-DDRQVKLWRMNDT 357 + N F G + + N + P+ ++ +G+ D+ + +W + Sbjct: 417 ---IRYRNFRTFTGTERI----------QFNCLAVDPSGEVVCAGSLDNFDIHVWSVQTG 463 Query: 358 KAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSEDK 459 + +D L GH VSC+ F + ++ S S DK Sbjct: 464 QL--LDALSGHEGPVSCLSFSQENSVLASASWDK 495 Score = 43.1 bits (100), Expect = 4e-04 Identities = 22/67 (32%), Positives = 38/67 (56%), Gaps = 3/67 (4%) Frame = +1 Query: 4 IWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPAD-- 177 +W+ Q+ + L+GH V C SF + ++ SAS D+T+R+W I R + V P + Sbjct: 457 VWSVQTGQLLDALSGHEGPVSCLSFSQENSVLASASWDKTIRIWSIFG-RSQQVEPIEVY 515 Query: 178 -DIMRLT 195 D++ L+ Sbjct: 516 SDVLALS 522 Score = 34.7 bits (78), Expect = 0.14 Identities = 19/74 (25%), Positives = 40/74 (54%), Gaps = 2/74 (2%) Frame = +1 Query: 241 YVL--EGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVM 414 Y+L +GH N ++ P +V+ ++D ++K+W + T + + T H ++V+ V Sbjct: 337 YILKQQGHFDSTNSLAYSPDGSRVVTASEDGKIKVWDI--TSGFCLATFEEHTSSVTAVQ 394 Query: 415 FHAKQDIIVSNSED 456 F + ++ S+S D Sbjct: 395 FAKRGQVMFSSSLD 408 Score = 34.3 bits (77), Expect = 0.18 Identities = 31/128 (24%), Positives = 50/128 (39%), Gaps = 10/128 (7%) Frame = +1 Query: 1 RIWNWQSRT---CVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSP 171 +IW+ S GH YVM A F ++ + + S D V VW+ T P Sbjct: 171 KIWSVDSEEKNLAATTFNGHRDYVMGAFFSHDQEKIYTVSKDGAVFVWEF------TKRP 224 Query: 172 ADDIMRLTQMNTDLFGGVD-------AVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQ 330 +DD ++ + D VD K+ + V +FHP L+ G + Sbjct: 225 SDDDDNESE-DDDKQEEVDISKYSWRITKKHFFYANQAKVKCVTFHPATRLLAVGFTSGE 283 Query: 331 VKLWRMND 354 +L+ + D Sbjct: 284 FRLYDLPD 291
>WDR33_HUMAN (Q9C0J8) WD-repeat protein 33 (WD-repeat protein WDC146)| Length = 1336 Score = 49.3 bits (116), Expect = 5e-06 Identities = 41/152 (26%), Positives = 61/152 (40%), Gaps = 4/152 (2%) Frame = +1 Query: 13 WQSR-TCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDIMR 189 WQS V + H + ASF P ++ + S D TVR+WD ++ + Sbjct: 188 WQSNMNNVKMFQAHKEAIREASFSPTDNKFATCSDDGTVRIWDFLRCHEERI-------- 239 Query: 190 LTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQ--VKLWRMNDTKA 363 L GH V +HPT L+VSG+ D Q +K W D K Sbjct: 240 -------------------LRGHGADVKCVDWHPTKGLVVSGSKDSQQPIKFW---DPKT 277 Query: 364 WE-VDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 + + TL H N V V + + +++ S D Sbjct: 278 GQSLATLHAHKNTVMEVKLNLNGNWLLTASRD 309 Score = 40.8 bits (94), Expect = 0.002 Identities = 43/172 (25%), Positives = 68/172 (39%), Gaps = 20/172 (11%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLD--QTVRVWDIGALRK-KTVSP 171 RIW++ +L GH V C +HP + LVVS S D Q ++ WD + T+ Sbjct: 227 RIWDFLRCHEERILRGHGADVKCVDWHPTKGLVVSGSKDSQQPIKFWDPKTGQSLATLHA 286 Query: 172 ADDIMRLTQMNTD----LFGGVDAVVK-----------YVLEGHDRGVNWASFHPTLP-L 303 + + ++N + L D + K V GH + ++HP L Sbjct: 287 HKNTVMEVKLNLNGNWLLTASRDHLCKLFDIRNLKEELQVFRGHKKEATAVAWHPVHEGL 346 Query: 304 IVSGADDRQVKLWRMNDTKAWEVDTLR-GHMNNVSCVMFHAKQDIIVSNSED 456 SG D + W + K EV + H + + +H I+ S S D Sbjct: 347 FASGGSDGSLLFWHVGVEK--EVGGMEMAHEGMIWSLAWHPLGHILCSGSND 396
>YAGE_SCHPO (Q9UTN4) Hypothetical WD-repeat protein C12G12.14c in chromosome I| Length = 509 Score = 48.9 bits (115), Expect = 7e-06 Identities = 32/121 (26%), Positives = 57/121 (47%), Gaps = 3/121 (2%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPK--EDLVVSASLDQTVRVWDIGALRKKTVSPA 174 + W+ ++ TC+A L GH + +M ASF + + + S D T RV+D+ A++ Sbjct: 231 KFWDPRTGTCIATLHGHKNTIMQASFQKNFGSNYLATVSRDSTCRVFDLRAMK------- 283 Query: 175 DDIMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLP-LIVSGADDRQVKLWRMN 351 D+ VL GH++ VN ++HP P L+ +G D V + ++ Sbjct: 284 -DVR-------------------VLRGHEKDVNCVTWHPLYPNLLTTGGSDGSVNHYSLD 323 Query: 352 D 354 + Sbjct: 324 E 324 Score = 41.6 bits (96), Expect = 0.001 Identities = 32/129 (24%), Positives = 51/129 (39%) Frame = +1 Query: 31 VAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDIMRLTQMNTD 210 V ++ H V +F P + V+AS D +++VW+ M+T+ Sbjct: 157 VKIVQAHEMEVRDVAFSPNDSKFVTASDDGSLKVWNF------------------HMSTE 198 Query: 211 LFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVDTLRGH 390 + L GH V +HP+ L+ SG+ D VK W + + TL GH Sbjct: 199 ---------ELKLTGHGWDVKTVDWHPSKGLLASGSKDNLVKFW--DPRTGTCIATLHGH 247 Query: 391 MNNVSCVMF 417 N + F Sbjct: 248 KNTIMQASF 256
>PWP2_MOUSE (Q8BU03) Periodic tryptophan protein 2 homolog| Length = 919 Score = 48.9 bits (115), Expect = 7e-06 Identities = 34/136 (25%), Positives = 60/136 (44%), Gaps = 17/136 (12%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 ++WN S C LT H+ V +F ++V++SLD TVR +D+ R + Sbjct: 398 KVWNTLSGFCFVTLTEHSSGVTGVTFTTTGHVIVTSSLDGTVRAFDLHRYRNFRTFTSPR 457 Query: 181 IMRLTQMNTDLFGGVDAV-----------------VKYVLEGHDRGVNWASFHPTLPLIV 309 + + + D G + + + VL GH+ V+ F+P ++ Sbjct: 458 PTQFSCVAVDSSGEIVSAGAQDSFEIFVWSMQTGRLLDVLSGHEGPVSGLCFNPMKSILA 517 Query: 310 SGADDRQVKLWRMNDT 357 S + D+ V+LW M D+ Sbjct: 518 SASWDKTVRLWDMFDS 533 Score = 43.5 bits (101), Expect = 3e-04 Identities = 22/66 (33%), Positives = 39/66 (59%), Gaps = 2/66 (3%) Frame = +1 Query: 4 IWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI--GALRKKTVSPAD 177 +W+ Q+ + VL+GH V F+P + ++ SAS D+TVR+WD+ K+T++ Sbjct: 485 VWSMQTGRLLDVLSGHEGPVSGLCFNPMKSILASASWDKTVRLWDMFDSWRTKETLTLTS 544 Query: 178 DIMRLT 195 D + +T Sbjct: 545 DALAVT 550 Score = 41.2 bits (95), Expect = 0.001 Identities = 39/169 (23%), Positives = 71/169 (42%), Gaps = 17/169 (10%) Frame = +1 Query: 4 IWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI--GALRKKTVSPAD 177 +W WQS + V GH + ++ ++ P +V+ D V+VW+ G + Sbjct: 357 VWEWQSESYVLKQQGHFNSMVALAYSPDGQYIVTGGDDGKVKVWNTLSGFCFVTLTEHSS 416 Query: 178 DIMRLTQMNTD---LFGGVDAVVK-YVLEGHDRGVNWASFHPTL----------PLIVSG 315 + +T T + +D V+ + L + + S PT ++ +G Sbjct: 417 GVTGVTFTTTGHVIVTSSLDGTVRAFDLHRYRNFRTFTSPRPTQFSCVAVDSSGEIVSAG 476 Query: 316 ADDR-QVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSEDK 459 A D ++ +W M + +D L GH VS + F+ + I+ S S DK Sbjct: 477 AQDSFEIFVWSMQTGRL--LDVLSGHEGPVSGLCFNPMKSILASASWDK 523 Score = 36.2 bits (82), Expect = 0.047 Identities = 25/74 (33%), Positives = 38/74 (51%), Gaps = 2/74 (2%) Frame = +1 Query: 241 YVL--EGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVM 414 YVL +GH + ++ P IV+G DD +VK+W N + TL H + V+ V Sbjct: 365 YVLKQQGHFNSMVALAYSPDGQYIVTGGDDGKVKVW--NTLSGFCFVTLTEHSSGVTGVT 422 Query: 415 FHAKQDIIVSNSED 456 F +IV++S D Sbjct: 423 FTTTGHVIVTSSLD 436
>CAF1B_MOUSE (Q9D0N7) Chromatin assembly factor 1 subunit B (CAF-1 subunit B)| (Chromatin assembly factor I p60 subunit) (CAF-I 60 kDa subunit) (CAF-Ip60) Length = 572 Score = 48.9 bits (115), Expect = 7e-06 Identities = 46/152 (30%), Positives = 68/152 (44%), Gaps = 24/152 (15%) Frame = +1 Query: 73 SFHPKEDLVVSASLD-QTVRVWDIGALRKKTVSPADDIMRLTQMNTDLFGGVD--AVVKY 243 ++H KE + SLD Q W I L V A I +L + G D A+V++ Sbjct: 9 AWHNKEPVY---SLDFQHGATWKIHRLASAGVDTAVRIWKLER-------GPDGKAIVEF 58 Query: 244 V--LEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWE---------------- 369 + L H + VN F PT ++ SG DD + LW+MND+K E Sbjct: 59 LSNLARHTKAVNVVRFSPTGEILASGGDDAVILLWKMNDSKEPEQIAFQDEEEAQLNKEN 118 Query: 370 ---VDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 V TLRGH+ +V + + +++ S S D Sbjct: 119 WTVVKTLRGHLEDVYDICWATDGNLMTSASVD 150 Score = 31.6 bits (70), Expect = 1.2 Identities = 18/52 (34%), Positives = 27/52 (51%) Frame = +1 Query: 10 NWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTV 165 NW T V L GH V + +L+ SAS+D TV +WD+ +K ++ Sbjct: 118 NW---TVVKTLRGHLEDVYDICWATDGNLMTSASVDNTVIIWDVSKGQKISI 166
>PLAP_MOUSE (P27612) Phospholipase A-2-activating protein (PLAP)| Length = 646 Score = 48.9 bits (115), Expect = 7e-06 Identities = 35/158 (22%), Positives = 66/158 (41%), Gaps = 11/158 (6%) Frame = +1 Query: 13 WQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDIMRL 192 W + C+ L GH V P++ L+++ S D+T+++W G + + D + L Sbjct: 81 WLNDKCMMTLQGHTAAVWAVKILPEQGLMLTGSADKTIKLWKAGRCERTFLGHEDCVRGL 140 Query: 193 TQMNTDLFGGV--DAVVK---------YVLEGHDRGVNWASFHPTLPLIVSGADDRQVKL 339 ++ F DA ++ V GH + S P V+ A+DR +++ Sbjct: 141 AILSETEFLSCANDASIRRWQITGECLEVYFGHTNYIYSISVFPNSKDFVTTAEDRSLRI 200 Query: 340 WRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSE 453 W+ + T+R ++ C DI+V S+ Sbjct: 201 WKHGEC----AQTIRLPAQSIWCCCVLENGDIVVGASD 234
>GBB1_RAT (P54311) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 1 (Transducin beta chain 1) Length = 339 Score = 48.9 bits (115), Expect = 7e-06 Identities = 41/153 (26%), Positives = 62/153 (40%), Gaps = 17/153 (11%) Frame = +1 Query: 4 IWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI--GALRKKTVSPAD 177 +W+ ++ TGH VM S P L VS + D + ++WD+ G R+ Sbjct: 167 LWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHES 226 Query: 178 DIMRL---TQMNTDLFGGVDAVVK---------YVLEGHDR---GVNWASFHPTLPLIVS 312 DI + N G DA + + HD G+ SF + L+++ Sbjct: 227 DINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLA 286 Query: 313 GADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCV 411 G DD +W + KA L GH N VSC+ Sbjct: 287 GYDDFNCNVW--DALKADRAGVLAGHDNRVSCL 317
>GBB1_MOUSE (P62874) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 1 (Transducin beta chain 1) Length = 339 Score = 48.9 bits (115), Expect = 7e-06 Identities = 41/153 (26%), Positives = 62/153 (40%), Gaps = 17/153 (11%) Frame = +1 Query: 4 IWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI--GALRKKTVSPAD 177 +W+ ++ TGH VM S P L VS + D + ++WD+ G R+ Sbjct: 167 LWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHES 226 Query: 178 DIMRL---TQMNTDLFGGVDAVVK---------YVLEGHDR---GVNWASFHPTLPLIVS 312 DI + N G DA + + HD G+ SF + L+++ Sbjct: 227 DINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLA 286 Query: 313 GADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCV 411 G DD +W + KA L GH N VSC+ Sbjct: 287 GYDDFNCNVW--DALKADRAGVLAGHDNRVSCL 317
>GBB1_HUMAN (P62873) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 1 (Transducin beta chain 1) Length = 339 Score = 48.9 bits (115), Expect = 7e-06 Identities = 41/153 (26%), Positives = 62/153 (40%), Gaps = 17/153 (11%) Frame = +1 Query: 4 IWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI--GALRKKTVSPAD 177 +W+ ++ TGH VM S P L VS + D + ++WD+ G R+ Sbjct: 167 LWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHES 226 Query: 178 DIMRL---TQMNTDLFGGVDAVVK---------YVLEGHDR---GVNWASFHPTLPLIVS 312 DI + N G DA + + HD G+ SF + L+++ Sbjct: 227 DINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLA 286 Query: 313 GADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCV 411 G DD +W + KA L GH N VSC+ Sbjct: 287 GYDDFNCNVW--DALKADRAGVLAGHDNRVSCL 317
>GBB1_CRIGR (Q6TMK6) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 1 (Transducin beta chain 1) Length = 339 Score = 48.9 bits (115), Expect = 7e-06 Identities = 41/153 (26%), Positives = 62/153 (40%), Gaps = 17/153 (11%) Frame = +1 Query: 4 IWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI--GALRKKTVSPAD 177 +W+ ++ TGH VM S P L VS + D + ++WD+ G R+ Sbjct: 167 LWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHES 226 Query: 178 DIMRL---TQMNTDLFGGVDAVVK---------YVLEGHDR---GVNWASFHPTLPLIVS 312 DI + N G DA + + HD G+ SF + L+++ Sbjct: 227 DINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLA 286 Query: 313 GADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCV 411 G DD +W + KA L GH N VSC+ Sbjct: 287 GYDDFNCNVW--DALKADRAGVLAGHDNRVSCL 317
>GBB1_CANFA (P62872) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 1 (Transducin beta chain 1) Length = 339 Score = 48.9 bits (115), Expect = 7e-06 Identities = 41/153 (26%), Positives = 62/153 (40%), Gaps = 17/153 (11%) Frame = +1 Query: 4 IWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI--GALRKKTVSPAD 177 +W+ ++ TGH VM S P L VS + D + ++WD+ G R+ Sbjct: 167 LWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHES 226 Query: 178 DIMRL---TQMNTDLFGGVDAVVK---------YVLEGHDR---GVNWASFHPTLPLIVS 312 DI + N G DA + + HD G+ SF + L+++ Sbjct: 227 DINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLA 286 Query: 313 GADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCV 411 G DD +W + KA L GH N VSC+ Sbjct: 287 GYDDFNCNVW--DALKADRAGVLAGHDNRVSCL 317
>GBB1_BOVIN (P62871) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 1 (Transducin beta chain 1) Length = 339 Score = 48.9 bits (115), Expect = 7e-06 Identities = 41/153 (26%), Positives = 62/153 (40%), Gaps = 17/153 (11%) Frame = +1 Query: 4 IWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI--GALRKKTVSPAD 177 +W+ ++ TGH VM S P L VS + D + ++WD+ G R+ Sbjct: 167 LWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHES 226 Query: 178 DIMRL---TQMNTDLFGGVDAVVK---------YVLEGHDR---GVNWASFHPTLPLIVS 312 DI + N G DA + + HD G+ SF + L+++ Sbjct: 227 DINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLA 286 Query: 313 GADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCV 411 G DD +W + KA L GH N VSC+ Sbjct: 287 GYDDFNCNVW--DALKADRAGVLAGHDNRVSCL 317
>PLAP_HUMAN (Q9Y263) Phospholipase A-2-activating protein (PLAP) (PLA2P)| Length = 738 Score = 48.5 bits (114), Expect = 9e-06 Identities = 38/159 (23%), Positives = 68/159 (42%), Gaps = 12/159 (7%) Frame = +1 Query: 13 WQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDIMR- 189 W + C+ L GH V P++ L+++ S D+TV++W G ++T S +D +R Sbjct: 81 WLNDKCMMTLQGHTAAVWAVKILPEQGLMLTGSADKTVKLWKAGRC-ERTFSGHEDCVRG 139 Query: 190 --LTQMNTDLFGGVDAVVK---------YVLEGHDRGVNWASFHPTLPLIVSGADDRQVK 336 + L DA ++ V GH + S P V+ A+DR ++ Sbjct: 140 LAILSETEFLSCANDASIRRWQITGECLEVYYGHTNYIYSISVFPNCRDFVTTAEDRSLR 199 Query: 337 LWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSE 453 +W+ + T+R ++ C DI+V S+ Sbjct: 200 IWKHGEC----AQTIRLPAQSIWCCCVLDNGDIVVGASD 234 Score = 33.5 bits (75), Expect = 0.30 Identities = 33/140 (23%), Positives = 55/140 (39%), Gaps = 24/140 (17%) Frame = +1 Query: 40 LTGHNHYVMCASFHPKED-----LVVSASLDQTVRVWDIGAL--------RKKTVSPADD 180 ++GH+++V C P D L+ + D + ++ + + K TV Sbjct: 4 MSGHSNFVSCVCIIPSSDIYPHGLIATGGNDHNICIFSLDSPMPLYILKGHKNTVCS--- 60 Query: 181 IMRLTQMNTDLFGGVDAVVK--------YVLEGHDRGVNWASFHPTLPLIVSGADDRQVK 336 + + T L G D K L+GH V P L+++G+ D+ VK Sbjct: 61 -LSSGKFGTLLSGSWDTTAKVWLNDKCMMTLQGHTAAVWAVKILPEQGLMLTGSADKTVK 119 Query: 337 LW---RMNDTKAWEVDTLRG 387 LW R T + D +RG Sbjct: 120 LWKAGRCERTFSGHEDCVRG 139
>GBLP_SCHPO (Q10281) Guanine nucleotide-binding protein beta subunit-like| protein (Receptor of activated protein kinase C) Length = 314 Score = 48.5 bits (114), Expect = 9e-06 Identities = 39/143 (27%), Positives = 57/143 (39%), Gaps = 2/143 (1%) Frame = +1 Query: 40 LTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDIMRLTQMNTDLFG 219 LTGH+H+V + +SAS D+T+R+WD+ Sbjct: 59 LTGHSHFVSDCALSFDSHYALSASWDKTIRLWDL-------------------------- 92 Query: 220 GVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVDTLRGHMNN 399 + GH V S P +VSG+ D+ +K+W + + + T GH + Sbjct: 93 -EKGECTHQFVGHTSDVLSVSISPDNRQVVSGSRDKTIKIWNIIGNCKYTI-TDGGHSDW 150 Query: 400 VSCVMFHAKQD--IIVSNSEDKA 462 VSCV F D VS DKA Sbjct: 151 VSCVRFSPNPDNLTFVSAGWDKA 173 Score = 46.6 bits (109), Expect = 3e-05 Identities = 37/137 (27%), Positives = 59/137 (43%), Gaps = 18/137 (13%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPA-- 174 R+W+ + C GH V+ S P VVS S D+T+++W+I K T++ Sbjct: 88 RLWDLEKGECTHQFVGHTSDVLSVSISPDNRQVVSGSRDKTIKIWNIIGNCKYTITDGGH 147 Query: 175 DDIMRLTQMN------TDLFGGVDAVVK-YVLE---------GHDRGVNWASFHPTLPLI 306 D + + + T + G D VK + LE GH V+ + P L Sbjct: 148 SDWVSCVRFSPNPDNLTFVSAGWDKAVKVWDLETFSLRTSHYGHTGYVSAVTISPDGSLC 207 Query: 307 VSGADDRQVKLWRMNDT 357 SG D + LW +N++ Sbjct: 208 ASGGRDGTLMLWDLNES 224
>STRAP_HUMAN (Q9Y3F4) Serine-threonine kinase receptor-associated protein| (UNR-interacting protein) (WD-40 repeat protein PT-WD) (MAP activator with WD repeats) Length = 350 Score = 48.5 bits (114), Expect = 9e-06 Identities = 37/151 (24%), Positives = 70/151 (46%), Gaps = 12/151 (7%) Frame = +1 Query: 40 LTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRK-------KTVS-----PADDI 183 ++GH + A + ++ ++SA D+TVR+WD + + +VS P +I Sbjct: 139 ISGHTSGIKKALWCSEDKQILSAD-DKTVRLWDHATMTEVKSLNFNMSVSSMEYIPEGEI 197 Query: 184 MRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKA 363 + +T + F ++ +N AS HP +V+G +D KL++ + Sbjct: 198 LVITYGRSIAFHSAVSLDPIKSFEAPATINSASLHPEKEFLVAGGED--FKLYKYDYNSG 255 Query: 364 WEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 E+++ +GH + CV F ++ S SED Sbjct: 256 EELESYKGHFGPIHCVRFSPDGELYASGSED 286 Score = 33.5 bits (75), Expect = 0.30 Identities = 36/164 (21%), Positives = 65/164 (39%), Gaps = 15/164 (9%) Frame = +1 Query: 31 VAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDIMRLTQMNTD 210 + GH V A+ + +A+ D T +VWD + + I++ D Sbjct: 52 IGTFLGHKGAVWGATLNKDATKAATAAADFTAKVWDAVSGDELMTLAHKHIVKTVDFTQD 111 Query: 211 ----LFGGVDAVVKYV-----------LEGHDRGVNWASFHPTLPLIVSGADDRQVKLWR 345 L GG D +++ + GH G+ A + I+S ADD+ V+LW Sbjct: 112 SNYLLTGGQDKLLRIYDLNKPEAEPKEISGHTSGIKKALWCSEDKQILS-ADDKTVRLW- 169 Query: 346 MNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSEDKAFASGM 477 + EV +L +M+ S + ++++ AF S + Sbjct: 170 -DHATMTEVKSLNFNMSVSSMEYIPEGEILVITYGRSIAFHSAV 212
>GRWD1_RAT (Q5XI13) Glutamate-rich WD repeat-containing protein 1| Length = 445 Score = 48.5 bits (114), Expect = 9e-06 Identities = 41/150 (27%), Positives = 60/150 (40%), Gaps = 2/150 (1%) Frame = +1 Query: 7 WNWQSRTCVAVLTGHNHYVMCASFHPKEDLV-VSASLDQTVRVWDIGALRKKTVSPADDI 183 WN R V GH V + P ED V S S D ++R+WDI A K Sbjct: 249 WNVDQRPFV----GHTRSVEDLQWSPTEDTVFASCSADASIRIWDIRAAPGK-------- 296 Query: 184 MRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKA 363 A + HD VN S+ P ++SG DD +K+W + K+ Sbjct: 297 ---------------ACMLTTAAAHDGDVNVISWSRREPFLLSGGDDGTLKVWDLRQFKS 341 Query: 364 WE-VDTLRGHMNNVSCVMFHAKQDIIVSNS 450 V T + H+ V+ V +H + + + S Sbjct: 342 GSPVATFKQHVAPVTSVEWHPQDSGVFAAS 371
>TBL3_HUMAN (Q12788) WD-repeat protein SAZD (Transducin beta-like 3 protein)| Length = 519 Score = 48.5 bits (114), Expect = 9e-06 Identities = 37/122 (30%), Positives = 54/122 (44%), Gaps = 6/122 (4%) Frame = +1 Query: 1 RIWNWQSR---TCVAVLTGHNHYV--MCASFHPKEDLVVSASLDQTVRVWDIG-ALRKKT 162 RIW CVA +GH H V +C S KE +V+ S D TV++W + AL K Sbjct: 287 RIWRMNKAGQVMCVAQGSGHTHSVGTVCCS-RLKESFLVTGSQDCTVKLWPLPKALLSKN 345 Query: 163 VSPADDIMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLW 342 +P + + L T HD+ +N + P L+ +G+ DR KLW Sbjct: 346 TAPDNGPILLQAHTTQ-------------RCHDKDINSVAIAPNDKLLATGSQDRTAKLW 392 Query: 343 RM 348 + Sbjct: 393 AL 394 Score = 40.4 bits (93), Expect = 0.002 Identities = 35/131 (26%), Positives = 51/131 (38%), Gaps = 2/131 (1%) Frame = +1 Query: 73 SFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDIMRLTQMNTDLFGGVDAVVKYVLE 252 +F P L+ + D VRVWDI + T F G VV V Sbjct: 2 AFDPTSTLLATGGCDGAVRVWDI----------------VRHYGTHHFRGSPGVVHLV-- 43 Query: 253 GHDRGVNWASFH--PTLPLIVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAK 426 +FH PT L+ S A D +++W + D V L H + V+ + F A Sbjct: 44 ---------AFHPDPTRLLLFSSATDAAIRVWSLQDRSCLAV--LTAHYSAVTSLAFSAD 92 Query: 427 QDIIVSNSEDK 459 ++S+ DK Sbjct: 93 GHTMLSSGRDK 103 Score = 39.3 bits (90), Expect = 0.006 Identities = 17/57 (29%), Positives = 30/57 (52%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSP 171 R+W+ Q R+C+AVLT H V +F ++S+ D+ +WD+ + + P Sbjct: 64 RVWSLQDRSCLAVLTAHYSAVTSLAFSADGHTMLSSGRDKICIIWDLQSCQATRTVP 120 Score = 29.3 bits (64), Expect = 5.7 Identities = 20/56 (35%), Positives = 31/56 (55%), Gaps = 4/56 (7%) Frame = +1 Query: 301 LIVSGADDRQVKLWRMNDTKAWEVDTL---RGHMNNVSCV-MFHAKQDIIVSNSED 456 L S A D+ V++WRMN KA +V + GH ++V V K+ +V+ S+D Sbjct: 276 LFASCAKDQSVRIWRMN--KAGQVMCVAQGSGHTHSVGTVCCSRLKESFLVTGSQD 329
>STRAP_MOUSE (Q9Z1Z2) Serine-threonine kinase receptor-associated protein| (UNR-interacting protein) Length = 351 Score = 48.1 bits (113), Expect = 1e-05 Identities = 37/151 (24%), Positives = 69/151 (45%), Gaps = 12/151 (7%) Frame = +1 Query: 40 LTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRK-------KTVS-----PADDI 183 ++GH + A + + ++SA D+TVR+WD + + +VS P +I Sbjct: 139 ISGHTSGIKKALWCSDDKQILSAD-DKTVRLWDHATMTEVKSLNFNMSVSSMEYIPEGEI 197 Query: 184 MRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKA 363 + +T + F ++ +N AS HP +V+G +D KL++ + Sbjct: 198 LVITYGRSIAFHSAVSLEPIKSFEAPATINSASLHPEKEFLVAGGED--FKLYKYDYNSG 255 Query: 364 WEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 E+++ +GH + CV F ++ S SED Sbjct: 256 EELESYKGHFGPIHCVRFSPDGELYASGSED 286 Score = 33.5 bits (75), Expect = 0.30 Identities = 36/164 (21%), Positives = 65/164 (39%), Gaps = 15/164 (9%) Frame = +1 Query: 31 VAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDIMRLTQMNTD 210 + GH V A+ + +A+ D T +VWD + + I++ D Sbjct: 52 IGTFLGHKGAVWGATLNKDATKAATAAADFTAKVWDAVSGDELMTLAHKHIVKTVDFTQD 111 Query: 211 ----LFGGVDAVVKYV-----------LEGHDRGVNWASFHPTLPLIVSGADDRQVKLWR 345 L GG D +++ + GH G+ A + I+S ADD+ V+LW Sbjct: 112 SNYLLTGGQDKLLRIYDLNKPEAEPKEISGHTSGIKKALWCSDDKQILS-ADDKTVRLW- 169 Query: 346 MNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSEDKAFASGM 477 + EV +L +M+ S + ++++ AF S + Sbjct: 170 -DHATMTEVKSLNFNMSVSSMEYIPEGEILVITYGRSIAFHSAV 212
>PLAP_RAT (P54319) Phospholipase A-2-activating protein (PLAP)| Length = 647 Score = 48.1 bits (113), Expect = 1e-05 Identities = 37/159 (23%), Positives = 68/159 (42%), Gaps = 12/159 (7%) Frame = +1 Query: 13 WQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDIMR- 189 W + C+ L GH V P++ L+++ S D+T+++W G ++T S +D +R Sbjct: 81 WLNDKCMMTLQGHTAAVWAVKILPEQGLMLTGSADKTIKLWKAGRC-ERTFSGHEDCVRG 139 Query: 190 --LTQMNTDLFGGVDAVVKY---------VLEGHDRGVNWASFHPTLPLIVSGADDRQVK 336 + L DA ++ V GH + S P V+ A+DR ++ Sbjct: 140 LAILSETEFLSCANDASIRRWQITGECLGVYYGHTNYIYSISVFPNCRDFVTTAEDRSLR 199 Query: 337 LWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSE 453 +W+ + T+R ++ C DI+V S+ Sbjct: 200 IWKHGEC----AQTIRLPAQSIWCCCVLDNGDIVVGASD 234 Score = 34.7 bits (78), Expect = 0.14 Identities = 31/136 (22%), Positives = 56/136 (41%), Gaps = 20/136 (14%) Frame = +1 Query: 40 LTGHNHYVMCASFHPKED-----LVVSASLDQTVRVWDIGALRKKTV--SPADDIMRLT- 195 ++GH+++V C P D L+ + D + ++ + + + D + L+ Sbjct: 4 MSGHSNFVSCVCIIPSSDIYPHGLIATGGNDHNICIFSLDSPMPLYILKGHKDTVCSLSS 63 Query: 196 -QMNTDLFGGVDAVVK--------YVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLW-- 342 + T L G D K L+GH V P L+++G+ D+ +KLW Sbjct: 64 GKFGTLLSGSWDTTAKVWLNDKCMMTLQGHTAAVWAVKILPEQGLMLTGSADKTIKLWKA 123 Query: 343 -RMNDTKAWEVDTLRG 387 R T + D +RG Sbjct: 124 GRCERTFSGHEDCVRG 139
>CDC4_YEAST (P07834) Cell division control protein 4 (F-box protein CDC4) (E3| ubiquitin ligase complex SCF subunit CDC4) Length = 779 Score = 47.8 bits (112), Expect = 2e-05 Identities = 37/161 (22%), Positives = 64/161 (39%), Gaps = 9/161 (5%) Frame = +1 Query: 4 IWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIG--------ALRKK 159 +W+ C+ +L+GH + + + +SAS+D T+R+WD+ + Sbjct: 554 VWDVAQMKCLYILSGHTDRIYSTIYDHERKRCISASMDTTIRIWDLENIWNNGECSYATN 613 Query: 160 TVSPADDIMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKL 339 + SP I+ Y L+GH V +VS A D ++ Sbjct: 614 SASPCAKILG---------------AMYTLQGHTALVGLLRLSD--KFLVSAAADGSIRG 656 Query: 340 WRMNDTKAWEVDTLRGHMNNVSCV-MFHAKQDIIVSNSEDK 459 W ND H N+S + F+ +I+VS SE++ Sbjct: 657 WDANDYSR----KFSYHHTNLSAITTFYVSDNILVSGSENQ 693 Score = 43.1 bits (100), Expect = 4e-04 Identities = 39/161 (24%), Positives = 66/161 (40%), Gaps = 9/161 (5%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDL--VVSASLDQTVRVWDIGALRKKTVSPA 174 R+W+ + C V GHN V C +++ +V+ S D T+ VW L K++ P Sbjct: 446 RVWDIKKGCCTHVFKGHNSTVRCLDIVEYKNIKYIVTGSRDNTLHVW---KLPKESSVPD 502 Query: 175 DD-------IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQV 333 + + N G VL GH V S H ++VSG+ D + Sbjct: 503 HGEEHDYPLVFHTPEENPYFVG--------VLRGHMASVRTVSGHGN--IVVSGSYDNTL 552 Query: 334 KLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 +W + K + L GH + + ++ ++ +S S D Sbjct: 553 IVWDVAQMKCLYI--LSGHTDRIYSTIYDHERKRCISASMD 591 Score = 37.7 bits (86), Expect = 0.016 Identities = 40/155 (25%), Positives = 67/155 (43%), Gaps = 6/155 (3%) Frame = +1 Query: 10 NWQSRTCV---AVLTGH-NHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPAD 177 NW + V L GH + C F +++ V++ + D+ +RV+D ++ KK + Sbjct: 364 NWYNPKFVPQRTTLRGHMTSVITCLQF--EDNYVITGADDKMIRVYD--SINKKFLLQ-- 417 Query: 178 DIMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDT 357 L GHD GV WA + ++VSG+ DR V++W + Sbjct: 418 -----------------------LSGHDGGV-WALKYAHGGILVSGSTDRTVRVWDIK-- 451 Query: 358 KAWEVDTLRGHMNNVSCVMFHAKQDI--IVSNSED 456 K +GH + V C+ ++I IV+ S D Sbjct: 452 KGCCTHVFKGHNSTVRCLDIVEYKNIKYIVTGSRD 486 Score = 36.6 bits (83), Expect = 0.036 Identities = 41/175 (23%), Positives = 69/175 (39%), Gaps = 23/175 (13%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 R+++ ++ + L+GH+ V + ++VS S D+TVRVWDI KK Sbjct: 405 RVYDSINKKFLLQLSGHDGGVWALKY-AHGGILVSGSTDRTVRVWDI----KK------- 452 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASF--HPTLPLIVSGADDRQVKLWRM-- 348 +V +GH+ V + + IV+G+ D + +W++ Sbjct: 453 ----------------GCCTHVFKGHNSTVRCLDIVEYKNIKYIVTGSRDNTLHVWKLPK 496 Query: 349 -------------------NDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 + + V LRGHM +V V H +I+VS S D Sbjct: 497 ESSVPDHGEEHDYPLVFHTPEENPYFVGVLRGHMASVRTVSGHG--NIVVSGSYD 549
>KMHB_DICDI (P90648) Myosin heavy chain kinase B (EC 2.7.11.7) (MHCK B)| Length = 732 Score = 47.8 bits (112), Expect = 2e-05 Identities = 47/205 (22%), Positives = 79/205 (38%), Gaps = 51/205 (24%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTV--SPA 174 ++W+ + C+ L GH+ V + K + S S D+T++VWD+ L K S A Sbjct: 525 KVWDLKKLRCIFTLEGHDKPVHTVLLNDK--YLFSGSSDKTIKVWDLKTLECKYTLESHA 582 Query: 175 DDIMRLTQMNTDLFGGV-DAVVK----------YVLEGHDRGVNWASFHPTLPLIVSGAD 321 + L LF G D +K Y L+GH + V T + SG+ Sbjct: 583 RAVKTLCISGQYLFSGSNDKTIKVWDLKTFRCNYTLKGHTKWVTTICILGTN--LYSGSY 640 Query: 322 DRQVKLWRM--------------------------------NDTKAWEVDTLR------G 387 D+ +++W + N K W+++TLR G Sbjct: 641 DKTIRVWNLKSLECSATLRGHDRWVEHMVICDKLLFTASDDNTIKIWDLETLRCNTTLEG 700 Query: 388 HMNNVSCVMFHAKQDIIVSNSEDKA 462 H V C+ + ++S S D++ Sbjct: 701 HNATVQCLAVWEDKKCVISCSHDQS 725 Score = 47.0 bits (110), Expect = 3e-05 Identities = 31/121 (25%), Positives = 51/121 (42%), Gaps = 4/121 (3%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHN----HYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVS 168 R+WN +S C A L GH+ H V+C + L+ +AS D T+++WD+ LR T Sbjct: 645 RVWNLKSLECSATLRGHDRWVEHMVIC------DKLLFTASDDNTIKIWDLETLRCNT-- 696 Query: 169 PADDIMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRM 348 LEGH+ V + ++S + D+ +++W Sbjct: 697 -------------------------TLEGHNATVQCLAVWEDKKCVISCSHDQSIRVWGW 731 Query: 349 N 351 N Sbjct: 732 N 732
>APAF_HUMAN (O14727) Apoptotic protease-activating factor 1 (Apaf-1)| Length = 1248 Score = 47.8 bits (112), Expect = 2e-05 Identities = 42/181 (23%), Positives = 73/181 (40%), Gaps = 28/181 (15%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWD-IGALRKKTVS--- 168 ++W+ + C + GH + V F P + L+ S S D T+++WD A +K+++ Sbjct: 726 KLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSANERKSINVKQ 785 Query: 169 -------PADD----------------IMRLTQMNTDLFG-GVDAVVKYVLEGHDRGVNW 276 P +D IM + LF ++ + GH + + Sbjct: 786 FFLNLEDPQEDMEVIVKCCSWSADGARIMVAAKNKIFLFDIHTSGLLGEIHTGHHSTIQY 845 Query: 277 ASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 F P L V V+LW N +V RGH++ V VMF +++S+D Sbjct: 846 CDFSPQNHLAVVALSQYCVELW--NTDSRSKVADCRGHLSWVHGVMFSPDGSSFLTSSDD 903 Query: 457 K 459 + Sbjct: 904 Q 904 Score = 43.5 bits (101), Expect = 3e-04 Identities = 37/164 (22%), Positives = 71/164 (43%), Gaps = 13/164 (7%) Frame = +1 Query: 4 IWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKT------- 162 +WN SR+ VA GH +V F P +++S DQT+R+W+ + K + Sbjct: 866 LWNTDSRSKVADCRGHLSWVHGVMFSPDGSSFLTSSDDQTIRLWETKKVCKNSAVMLKQE 925 Query: 163 ---VSPADDIMRLTQ---MNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADD 324 V +++M L L G + Y+ E V+ P L I G ++ Sbjct: 926 VDVVFQENEVMVLAVDHIRRLQLINGRTGQIDYLTEAQ---VSCCCLSPHLQYIAFGDEN 982 Query: 325 RQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 +++ + + + ++ + H V + F A + ++S+S+D Sbjct: 983 GAIEILELVNNRIFQ--SRFQHKKTVWHIQFTADEKTLISSSDD 1024 Score = 41.6 bits (96), Expect = 0.001 Identities = 34/133 (25%), Positives = 62/133 (46%), Gaps = 15/133 (11%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKK------- 159 ++WNWQ C+ L GH V K ++S S D TV+VW+I K+ Sbjct: 1028 QVWNWQLDKCI-FLRGHQETVKDFRLL-KNSRLLSWSFDGTVKVWNIITGNKEKDFVCHQ 1085 Query: 160 -TVSPAD---DIMRLTQMNTDLFGGV---DAVVK-YVLEGHDRGVNWASFHPTLPLIVSG 315 TV D D + + + D + D ++ + L GH+ V ++F L+ +G Sbjct: 1086 GTVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHELRGHNGCVRCSAFSVDSTLLATG 1145 Query: 316 ADDRQVKLWRMND 354 D+ ++++W +++ Sbjct: 1146 DDNGEIRIWNVSN 1158
>PWP2_SCHPO (Q9C1X1) Periodic tryptophan protein 2 homolog| Length = 854 Score = 47.8 bits (112), Expect = 2e-05 Identities = 31/131 (23%), Positives = 57/131 (43%), Gaps = 17/131 (12%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 ++W+ S C+ T H V F + +++ S+SLD +VR WD+ R A Sbjct: 364 KVWDMNSGFCIVTFTQHTSAVSGLCFSKRGNVLFSSSLDGSVRAWDLIRYRNFRTFTAPS 423 Query: 181 IMRLTQMNTDLFGGV-----------------DAVVKYVLEGHDRGVNWASFHPTLPLIV 309 ++ + + D G + + L GH+ V+ SF+ + L+ Sbjct: 424 RVQFSCIAVDPSGEIVCAGSQDSFEIFMWSVQTGQLLETLAGHEGPVSSLSFNSSGSLLA 483 Query: 310 SGADDRQVKLW 342 SG+ D+ V++W Sbjct: 484 SGSWDKTVRIW 494 Score = 39.3 bits (90), Expect = 0.006 Identities = 18/46 (39%), Positives = 26/46 (56%) Frame = +1 Query: 4 IWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI 141 +W+ Q+ + L GH V SF+ L+ S S D+TVR+WDI Sbjct: 451 MWSVQTGQLLETLAGHEGPVSSLSFNSSGSLLASGSWDKTVRIWDI 496 Score = 34.7 bits (78), Expect = 0.14 Identities = 34/152 (22%), Positives = 71/152 (46%), Gaps = 17/152 (11%) Frame = +1 Query: 52 NHYVMCASFHPKEDLVVSASLDQTVRVWDIGA---LRKKTVSPADDIMRLTQMNTDLFGG 222 N + CA+FHP +L+V ++++ + L + +++ ++ I LT +T + Sbjct: 254 NSKLRCAAFHPTSNLLVVGFSSGLFGIYELPSFTMLYQLSITQSN-IDTLTVNSTGDWIA 312 Query: 223 VDAVV------------KYVL--EGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTK 360 + + YVL + H ++ + I++GADD ++K+W MN Sbjct: 313 IGSSKLGQLLVWEWQSESYVLKQQSHYDALSTLQYSSDGQRIITGADDGKIKVWDMN--S 370 Query: 361 AWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 + + T H + VS + F + +++ S+S D Sbjct: 371 GFCIVTFTQHTSAVSGLCFSKRGNVLFSSSLD 402
>TAF5L_MOUSE (Q91WQ5) TAF5-like RNA polymerase II p300/CBP-associated| factor-associated factor 65 kDa subunit 5L (PCAF-associated factor 65 beta) (PAF65-beta) Length = 589 Score = 47.8 bits (112), Expect = 2e-05 Identities = 37/145 (25%), Positives = 57/145 (39%) Frame = +1 Query: 25 TCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDIMRLTQMN 204 T + +L GH V F ++S S D ++R WD+G+ N Sbjct: 333 TEMKILRGHCGPVYSTRFLADSSGLLSCSEDMSIRYWDLGSF----------------TN 376 Query: 205 TDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVDTLR 384 T L+ +GH V P SG+ DR +LW + T + + Sbjct: 377 TVLY-----------QGHAYPVWDVDISPFSLYFASGSHDRTARLWSFDRT--YPLRIYA 423 Query: 385 GHMNNVSCVMFHAKQDIIVSNSEDK 459 GH+ +V CV FH + + + S DK Sbjct: 424 GHLADVDCVKFHPNSNYLATGSTDK 448 Score = 44.3 bits (103), Expect = 2e-04 Identities = 23/59 (38%), Positives = 32/59 (54%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPAD 177 ++W+ S T L GH + +F P L+ SAS+D +VRVWDI + T PAD Sbjct: 493 KLWDLASGTLFKELRGHTDSITSLAFSPDSGLIASASMDNSVRVWDIRSTCCNT--PAD 549 Score = 44.3 bits (103), Expect = 2e-04 Identities = 39/169 (23%), Positives = 65/169 (38%), Gaps = 15/169 (8%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIG-----ALRKKTV 165 R W+ S T + GH + V P S S D+T R+W + + Sbjct: 367 RYWDLGSFTNTVLYQGHAYPVWDVDISPFSLYFASGSHDRTARLWSFDRTYPLRIYAGHL 426 Query: 166 SPADDIMRLTQMNTDLFGGVDAVVKY----------VLEGHDRGVNWASFHPTLPLIVSG 315 + D + N G D V+ + GH V SF P + S Sbjct: 427 ADVDCVKFHPNSNYLATGSTDKTVRLWSAQQGNSVRLFTGHRGPVLSLSFSPNGKYLASA 486 Query: 316 ADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSEDKA 462 +D+++KLW + ++ LRGH ++++ + F +I S S D + Sbjct: 487 GEDQRLKLWDLASGTLFK--ELRGHTDSITSLAFSPDSGLIASASMDNS 533
>GBB1_XENLA (P79959) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 1 (Transducin beta chain 1) (XGbeta1) Length = 340 Score = 47.4 bits (111), Expect = 2e-05 Identities = 39/153 (25%), Positives = 62/153 (40%), Gaps = 17/153 (11%) Frame = +1 Query: 4 IWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI--GALRKKTVSPAD 177 +W+ ++ TGH VM S P VS + D + ++WD+ G R+ Sbjct: 168 LWDIETGQQTTTFTGHTGDVMSLSLAPDSRCFVSGACDASAKLWDVREGMCRQTFTGHES 227 Query: 178 DIMRL---TQMNTDLFGGVDAVVK---------YVLEGHDR---GVNWASFHPTLPLIVS 312 DI + N G DA + ++ HD G+ +F + L+++ Sbjct: 228 DINAICFFPNGNAFATGSDDATCRLFDLRADQELMVYSHDNIICGITSVAFSKSGRLLLA 287 Query: 313 GADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCV 411 G DD +W + KA L GH N VSC+ Sbjct: 288 GYDDFNCNVW--DTLKADRAGVLAGHDNRVSCL 318 Score = 38.1 bits (87), Expect = 0.012 Identities = 30/154 (19%), Positives = 61/154 (39%), Gaps = 15/154 (9%) Frame = +1 Query: 40 LTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTV--SPADDIMRLT------ 195 L GH Y+ C F ++ S+ D T +WDI ++ T D+M L+ Sbjct: 139 LAGHTGYLSCCRFLDDNQIITSSG-DTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDSR 197 Query: 196 -------QMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMND 354 + L+ + + + GH+ +N F P +G+DD +L+ + Sbjct: 198 CFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRA 257 Query: 355 TKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 + V + + ++ V F ++++ +D Sbjct: 258 DQELMVYSHDNIICGITSVAFSKSGRLLLAGYDD 291
>PWP2_CAEEL (P91341) Periodic tryptophan protein 2 homolog| Length = 910 Score = 47.0 bits (110), Expect = 3e-05 Identities = 37/142 (26%), Positives = 57/142 (40%), Gaps = 17/142 (11%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 +IWN +S C H V + ++SASLD TVR D+ R + Sbjct: 385 KIWNSRSSFCTVTFDEHTSGVTAVKWTQSGRAILSASLDGTVRAHDLKRYRNFRTLVCPE 444 Query: 181 IMRLTQMNTDLFG-----GVDAVVKY------------VLEGHDRGVNWASFHPTLPLIV 309 +L + D G G V +L GH+ ++ H IV Sbjct: 445 PTQLATLAVDKAGDLVIAGAKEVFNIYIWSFETGHLLDILSGHESAISSIDIHGN--HIV 502 Query: 310 SGADDRQVKLWRMNDTKAWEVD 375 SG+ DR +K+W + D++A V+ Sbjct: 503 SGSWDRTIKMWTIVDSQAETVE 524 Score = 33.5 bits (75), Expect = 0.30 Identities = 15/61 (24%), Positives = 33/61 (54%) Frame = +1 Query: 4 IWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDI 183 IW++++ + +L+GH + H +VS S D+T+++W I + +TV + + Sbjct: 472 IWSFETGHLLDILSGHESAISSIDIHGNH--IVSGSWDRTIKMWTIVDSQAETVEVSHEA 529 Query: 184 M 186 + Sbjct: 530 L 530 Score = 31.6 bits (70), Expect = 1.2 Identities = 19/69 (27%), Positives = 33/69 (47%) Frame = +1 Query: 250 EGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQ 429 + H + A + P L+ +GA+D +VK+W N ++ T H + V+ V + Sbjct: 357 QAHSLRITTAEYSPDGSLMATGAEDGKVKIW--NSRSSFCTVTFDEHTSGVTAVKWTQSG 414 Query: 430 DIIVSNSED 456 I+S S D Sbjct: 415 RAILSASLD 423
>TAF73_SCHPO (O74319) Transcription initiation factor TFIID subunit taf73| (Transcription initiation factor TFIID 73 kDa subunit) (TAFII-73) Length = 642 Score = 47.0 bits (110), Expect = 3e-05 Identities = 27/114 (23%), Positives = 43/114 (37%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 R+W+ +++ + GHN + F P +AS DQT R+WD+ Sbjct: 428 RLWSKDTKSTIVKYAGHNAPIWDVQFSPFGYYFATASHDQTARLWDV------------- 474 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLW 342 A V GH V+ SFHP + +G+ D ++W Sbjct: 475 --------------EHAAPLRVFVGHQNDVDCVSFHPNAAYLATGSSDHTTRMW 514 Score = 43.5 bits (101), Expect = 3e-04 Identities = 17/47 (36%), Positives = 26/47 (55%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI 141 R+W+ + + V GH + V C SFHP + + S D T R+WD+ Sbjct: 470 RLWDVEHAAPLRVFVGHQNDVDCVSFHPNAAYLATGSSDHTTRMWDV 516 Score = 43.5 bits (101), Expect = 3e-04 Identities = 35/139 (25%), Positives = 52/139 (37%) Frame = +1 Query: 40 LTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDIMRLTQMNTDLFG 219 L GH V S P+++ ++S S D R+W K T S Sbjct: 399 LIGHTRPVFGVSISPQKEFILSCSEDGFTRLWS-----KDTKS----------------- 436 Query: 220 GVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVDTLRGHMNN 399 +VKY GH+ + F P + + D+ +LW + V GH N+ Sbjct: 437 ---TIVKYA--GHNAPIWDVQFSPFGYYFATASHDQTARLWDVEHAAPLRVFV--GHQND 489 Query: 400 VSCVMFHAKQDIIVSNSED 456 V CV FH + + S D Sbjct: 490 VDCVSFHPNAAYLATGSSD 508
>UTP13_YEAST (Q05946) U3 small nucleolar RNA-associated protein 13 (U3| snoRNA-associated protein 13) Length = 817 Score = 47.0 bits (110), Expect = 3e-05 Identities = 39/155 (25%), Positives = 61/155 (39%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 +IWN ++ A L H + SF + L+ ++S D+TV++W + Sbjct: 516 KIWNLENGELEATLANHKRGLWDVSFCQYDKLLATSSGDKTVKIWSL------------- 562 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTK 360 D F V LEGH V SF ++S D +K+W + + Sbjct: 563 ---------DTFS-----VMKTLEGHTNAVQRCSFINKQKQLISCGADGLIKIWDCSSGE 608 Query: 361 AWEVDTLRGHMNNVSCVMFHAKQDIIVSNSEDKAF 465 + TL GH N + + D+IVS D F Sbjct: 609 C--LKTLDGHNNRLWALSTMNDGDMIVSADADGVF 641 Score = 34.7 bits (78), Expect = 0.14 Identities = 15/45 (33%), Positives = 23/45 (51%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVW 135 +IW+ S C+ L GHN+ + S D++VSA D + W Sbjct: 600 KIWDCSSGECLKTLDGHNNRLWALSTMNDGDMIVSADADGVFQFW 644 Score = 34.3 bits (77), Expect = 0.18 Identities = 33/163 (20%), Positives = 65/163 (39%), Gaps = 11/163 (6%) Frame = +1 Query: 4 IWNWQSRTC----VAVLTGHNHYVMCASF-------HPKEDLVVSASLDQTVRVWDIGAL 150 +W + +C A GH+ V +P + +++AS D T++ W I Sbjct: 414 VWRYNENSCKFDIYAKYIGHSAAVTAVGLPNIVSKGYP--EFLLTASNDLTIKKWIIP-- 469 Query: 151 RKKTVSPADDIMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQ 330 K T S I+++++ Y H++ +N S P + + + D+ Sbjct: 470 -KPTASMDVQIIKVSE--------------YTRHAHEKDINALSVSPNDSIFATASYDKT 514 Query: 331 VKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSEDK 459 K+W + + + TL H + V F ++ ++S DK Sbjct: 515 CKIWNLENGEL--EATLANHKRGLWDVSFCQYDKLLATSSGDK 555
>PRP46_CANGA (Q6FJZ9) Pre-mRNA-splicing factor PRP46 (Pre-mRNA-processing| protein 46) Length = 427 Score = 47.0 bits (110), Expect = 3e-05 Identities = 39/156 (25%), Positives = 73/156 (46%), Gaps = 16/156 (10%) Frame = +1 Query: 37 VLTGHNHYVMCASFHPKE-DLVVSASLDQTVRVWDIGALRKKTVSPADDI----MRLTQM 201 V+ GH+ +V C + + + + S D+T+++W++ + + K A D+ + ++ Sbjct: 110 VIHGHHGWVRCIAMDKVDNEWFATGSNDKTIKIWNLASGKLKVTLKAHDMTVRDLAISNR 169 Query: 202 NTDLFG-GVDAVVK-YVLE---------GHDRGVNWASFHPTLPLIVSGADDRQVKLWRM 348 + +F D VK + LE GH GV+ HPT+ ++V+ D VK+W + Sbjct: 170 HPYMFSVSEDKTVKCWDLEKNTAIRNYHGHLSGVHTVDIHPTVDVVVTAGRDSVVKVWDI 229 Query: 349 NDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 V TL GH ++ V ++S+S D Sbjct: 230 R--TRLPVMTLPGHKGPITKVRCLPVDPQVISSSVD 263 Score = 45.1 bits (105), Expect = 1e-04 Identities = 35/143 (24%), Positives = 53/143 (37%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 + W+ + T + GH V HP D+VV+A D V+VWDI Sbjct: 183 KCWDLEKNTAIRNYHGHLSGVHTVDIHPTVDVVVTAGRDSVVKVWDIRT----------- 231 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTK 360 RL M L GH + P P ++S + D ++LW + K Sbjct: 232 --RLPVMT--------------LPGHKGPITKVRCLPVDPQVISSSVDASIRLWDLVAGK 275 Query: 361 AWEVDTLRGHMNNVSCVMFHAKQ 429 + +V L H V + H + Sbjct: 276 SMKV--LTHHQRTVRDISVHPSE 296 Score = 42.4 bits (98), Expect = 7e-04 Identities = 38/142 (26%), Positives = 61/142 (42%), Gaps = 23/142 (16%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI--GALRKKTVSPA 174 R+W+ + + VLT H V S HP E SA + +R W + G L VS Sbjct: 267 RLWDLVAGKSMKVLTHHQRTVRDISVHPSEFSFASACTND-IRSWLLPKGELLTNFVSQD 325 Query: 175 DDIMRLTQMNTD--LFGGVDAVVKYVLE---GH----------------DRGVNWASFHP 291 D++ +N D LF G D + GH +RG+ ++F Sbjct: 326 LDVINTVSINQDDVLFAGSDNGSLTFFDYKSGHKYQTFKTKEAPGSPESERGILSSTFDG 385 Query: 292 TLPLIVSGADDRQVKLWRMNDT 357 T +++G DR +K+W+ ++T Sbjct: 386 TGLRLLTGETDRTIKIWKQDET 407
>PRP46_DEBHA (Q6BU94) Pre-mRNA-splicing factor PRP46 (Pre-mRNA-processing| protein 46) Length = 417 Score = 47.0 bits (110), Expect = 3e-05 Identities = 33/134 (24%), Positives = 64/134 (47%), Gaps = 20/134 (14%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPA-- 174 R+W+ +SRT + VL+GH + + + ++++S+D T+R+WDI RK T A Sbjct: 236 RVWDLRSRTEIMVLSGHRSDITSIASQIGDPQIITSSMDATIRLWDI---RKATTQLALT 292 Query: 175 --DDIMRLTQMNTD----------------LFGGVDAVVKYVLEGHDRGVNWASFHPTLP 300 +RL M+ L G + + ++ G ++ +N S +P+ Sbjct: 293 HHSKSIRLMAMHPQEMTMCSGDTSGNLKEWLLPGGELLNEFGHSGENKIINTLSINPSNN 352 Query: 301 LIVSGADDRQVKLW 342 + SG DD +++ + Sbjct: 353 TLFSGYDDGRMEFY 366 Score = 46.6 bits (109), Expect = 3e-05 Identities = 35/152 (23%), Positives = 63/152 (41%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 +IW+ S A +TGH V + + + S S D+TV+ WD+ Sbjct: 147 KIWDLASLNLKATITGHIMGVRSLAVSSRYPYLFSGSEDKTVKCWDL------------- 193 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTK 360 + L G + Y GH G+ + HP L L+ +G D +++W + Sbjct: 194 -----ERTNSLLG--CQIRNY--HGHVGGIYAMALHPELDLLFTGGRDSVIRVWDLRSRT 244 Query: 361 AWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 E+ L GH ++++ + I+++S D Sbjct: 245 --EIMVLSGHRSDITSIASQIGDPQIITSSMD 274
>GBB1_PONPY (Q5R5W8) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 1 (Transducin beta chain 1) Length = 339 Score = 47.0 bits (110), Expect = 3e-05 Identities = 40/153 (26%), Positives = 62/153 (40%), Gaps = 17/153 (11%) Frame = +1 Query: 4 IWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI--GALRKKTVSPAD 177 +W+ ++ TGH VM S P L VS + D + ++WD+ G R+ Sbjct: 167 LWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHES 226 Query: 178 DIMRL---TQMNTDLFGGVDAVVK---------YVLEGHDR---GVNWASFHPTLPLIVS 312 DI + N G DA + + HD G+ SF + L+++ Sbjct: 227 DINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLA 286 Query: 313 GADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCV 411 G DD +W + KA L GH + VSC+ Sbjct: 287 GYDDFNCNVW--DALKADRAGVLAGHDDRVSCL 317
>GBB1_BRARE (Q6PH57) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 1 (Transducin beta chain 1) Length = 340 Score = 46.6 bits (109), Expect = 3e-05 Identities = 39/153 (25%), Positives = 62/153 (40%), Gaps = 17/153 (11%) Frame = +1 Query: 4 IWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI--GALRKKTVSPAD 177 +W+ ++ GH VM S P L VS + D + ++WD+ G R+ Sbjct: 168 LWDIETGQQTTTFAGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHES 227 Query: 178 DIMRL---TQMNTDLFGGVDAVVK---------YVLEGHDR---GVNWASFHPTLPLIVS 312 DI + N G DA + ++ HD G+ +F + L+++ Sbjct: 228 DINAICFFPNGNAFATGSDDATCRLFDLRADQELMVYSHDNIICGITSVAFSKSGRLLLA 287 Query: 313 GADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCV 411 G DD +W + KA L GH N VSC+ Sbjct: 288 GYDDFNCNVW--DALKADRAGVLAGHDNRVSCL 318 Score = 40.8 bits (94), Expect = 0.002 Identities = 37/154 (24%), Positives = 63/154 (40%), Gaps = 15/154 (9%) Frame = +1 Query: 40 LTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTV--SPADDIMRLTQM-NTD 210 L GH Y+ C F +V S+ D T +WDI ++ T D+M L+ +T Sbjct: 139 LAGHTGYLSCCRFLDDNQIVTSSG-DTTCALWDIETGQQTTTFAGHTGDVMSLSLAPDTR 197 Query: 211 LF--GGVDAVVKY----------VLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMND 354 LF G DA K GH+ +N F P +G+DD +L+ + Sbjct: 198 LFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRA 257 Query: 355 TKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 + V + + ++ V F ++++ +D Sbjct: 258 DQELMVYSHDNIICGITSVAFSKSGRLLLAGYDD 291
>PRP46_ASHGO (Q75BY3) Pre-mRNA-splicing factor PRP46 (Pre-mRNA-processing| protein 46) Length = 425 Score = 46.6 bits (109), Expect = 3e-05 Identities = 43/152 (28%), Positives = 56/152 (36%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 + W+ + T V G V HP DL+VSA D VRVWDI R ++ Sbjct: 181 KCWDLERNTVVRDFHGTLSGVHSVDLHPSLDLIVSAGRDSVVRVWDI---RSRS------ 231 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTK 360 L GH +N P P IVS + D VKLW + K Sbjct: 232 ------------------CVLTLAGHRGPINKVRCLPVDPQIVSCSTDATVKLWDLVAGK 273 Query: 361 AWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 + TL H NV + F+ + S D Sbjct: 274 --PMKTLTHHKRNVRDLAFNPTEFSFASACTD 303 Score = 46.6 bits (109), Expect = 3e-05 Identities = 45/156 (28%), Positives = 64/156 (41%), Gaps = 16/156 (10%) Frame = +1 Query: 37 VLTGHNHYVMCASFHPKEDL-VVSASLDQTVRVWDIGALRKKT-----VSPADDIMRLTQ 198 V+ GH +V C P ++ + S D T+RVWD+ + K + DI + Sbjct: 108 VINGHTGWVRCVCVDPVDNAWFATGSNDSTIRVWDLATGKLKVTLQGHIMTVRDICISAR 167 Query: 199 MNTDLFGGVDAVVK-YVLE---------GHDRGVNWASFHPTLPLIVSGADDRQVKLWRM 348 D +VK + LE G GV+ HP+L LIVS D V++W + Sbjct: 168 HPYMFSASQDKLVKCWDLERNTVVRDFHGTLSGVHSVDLHPSLDLIVSAGRDSVVRVWDI 227 Query: 349 NDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 V TL GH ++ V IVS S D Sbjct: 228 RSRSC--VLTLAGHRGPINKVRCLPVDPQIVSCSTD 261
>GBLP_NEUCR (Q01369) Guanine nucleotide-binding protein beta subunit-like| protein (Cross-pathway control WD-repeat protein cpc-2) Length = 316 Score = 46.6 bits (109), Expect = 3e-05 Identities = 44/143 (30%), Positives = 59/143 (41%), Gaps = 3/143 (2%) Frame = +1 Query: 40 LTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDIMRLTQMNTDLFG 219 L GH+H V +SAS D+T+R+W++ T T F Sbjct: 59 LHGHSHIVSDCVISSDGAYALSASWDKTLRLWELS----------------TGTTTRRF- 101 Query: 220 GVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWR-MNDTKAWEVDTLRGHMN 396 GH V SF IVSG+ DR +KLW + D K T +GH Sbjct: 102 ----------VGHTNDVLSVSFSADNRQIVSGSRDRTIKLWNTLGDCKF--TITEKGHTE 149 Query: 397 NVSCVMF--HAKQDIIVSNSEDK 459 VSCV F + + +IVS+ DK Sbjct: 150 WVSCVRFSPNPQNPVIVSSGWDK 172 Score = 46.2 bits (108), Expect = 5e-05 Identities = 36/154 (23%), Positives = 62/154 (40%), Gaps = 2/154 (1%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 R+W + T GH + V+ SF +VS S D+T+++W+ K T++ Sbjct: 88 RLWELSTGTTTRRFVGHTNDVLSVSFSADNRQIVSGSRDRTIKLWNTLGDCKFTITE--- 144 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASF--HPTLPLIVSGADDRQVKLWRMND 354 +GH V+ F +P P+IVS D+ VK+W ++ Sbjct: 145 -----------------------KGHTEWVSCVRFSPNPQNPVIVSSGWDKLVKVWELSS 181 Query: 355 TKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 K + D + GH ++ V + S +D Sbjct: 182 CKL-QTDHI-GHTGYINAVTISPDGSLCASGGKD 213
>WDR3_HUMAN (Q9UNX4) WD-repeat protein 3| Length = 943 Score = 46.6 bits (109), Expect = 3e-05 Identities = 37/149 (24%), Positives = 60/149 (40%), Gaps = 15/149 (10%) Frame = +1 Query: 61 VMCASFHPKEDLVVSASLDQTVRVWDIGALR-------KKTVSPADDIMR--------LT 195 V+C S+ P + L+ + LD TV+++ + L+ K DI Sbjct: 552 VLCVSYSPNQKLLAVSLLDCTVKIFYVDTLKFFLSLYGHKLPVICMDISHDGALIATGSA 611 Query: 196 QMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVD 375 N ++G L HD V + F P L + D ++K W + K + Sbjct: 612 DRNVKIWGLDFGDCHKSLFAHDDSVMYLQFVPKSHLFFTAGKDHKIKQWDAD--KFEHIQ 669 Query: 376 TLRGHMNNVSCVMFHAKQDIIVSNSEDKA 462 TL GH + C+ D +VS+S DK+ Sbjct: 670 TLEGHHQEIWCLAVSPSGDYVVSSSHDKS 698 Score = 40.8 bits (94), Expect = 0.002 Identities = 31/116 (26%), Positives = 51/116 (43%), Gaps = 15/116 (12%) Frame = +1 Query: 40 LTGHNHYVMCASFHPKEDLVVSASLDQTVRVW--DIGALRKKTVSPADDIMRLTQM-NTD 210 L GH V+C L+ + S D+ V++W D G K + D +M L + + Sbjct: 587 LYGHKLPVICMDISHDGALIATGSADRNVKIWGLDFGDCHKSLFAHDDSVMYLQFVPKSH 646 Query: 211 LF--GGVDAVVKY----------VLEGHDRGVNWASFHPTLPLIVSGADDRQVKLW 342 LF G D +K LEGH + + + P+ +VS + D+ ++LW Sbjct: 647 LFFTAGKDHKIKQWDADKFEHIQTLEGHHQEIWCLAVSPSGDYVVSSSHDKSLRLW 702 Score = 35.8 bits (81), Expect = 0.061 Identities = 14/44 (31%), Positives = 25/44 (56%) Frame = +1 Query: 7 WNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWD 138 W+ + L GH+ + C + P D VVS+S D+++R+W+ Sbjct: 660 WDADKFEHIQTLEGHHQEIWCLAVSPSGDYVVSSSHDKSLRLWE 703 Score = 31.2 bits (69), Expect = 1.5 Identities = 13/50 (26%), Positives = 25/50 (50%) Frame = +1 Query: 7 WNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRK 156 W+ ++ C + GH V +E +++ + D +RVWDI L++ Sbjct: 176 WDLDTQHCFKTMVGHRTEVWGLVLLSEEKRLITGASDSELRVWDIAYLQE 225 Score = 30.8 bits (68), Expect = 2.0 Identities = 33/166 (19%), Positives = 66/166 (39%), Gaps = 15/166 (9%) Frame = +1 Query: 4 IWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI----GALRKKTVSP 171 IW+ + + +L G V C P + D ++R++ + G + Sbjct: 49 IWDLRKGEKILILQGLKQEVTCLCPSPDGLHLAVGYEDGSIRIFSLLSGEGNVTFNGHKA 108 Query: 172 ADDIMRLTQMNTDLFGG---VDAVV--------KYVLEGHDRGVNWASFHPTLPLIVSGA 318 A ++ Q+ L G D +V Y L+GH + A F L+V+ Sbjct: 109 AITTLKYDQLGGRLASGSKDTDIIVWDVINESGLYRLKGHKDAITQALFLREKNLLVTSG 168 Query: 319 DDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 D VK W ++ ++ T+ GH V ++ +++ +++ + D Sbjct: 169 KDTMVKWWDLDTQHCFK--TMVGHRTEVWGLVLLSEEKRLITGASD 212
>GBB4_HUMAN (Q9HAV0) Guanine nucleotide-binding protein beta subunit 4| (Transducin beta chain 4) Length = 339 Score = 46.2 bits (108), Expect = 5e-05 Identities = 41/153 (26%), Positives = 64/153 (41%), Gaps = 17/153 (11%) Frame = +1 Query: 4 IWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI--GALRKKTVSPAD 177 +W+ ++ TGH+ VM S P VS + D + ++WDI G R+ Sbjct: 167 LWDIETAQQTTTFTGHSGDVMSLSLSPDMRTFVSGACDASSKLWDIRDGMCRQSFTGHVS 226 Query: 178 DIMRLTQM-NTDLF--GGVDAVVK---------YVLEGHDR---GVNWASFHPTLPLIVS 312 DI ++ N F G DA + +L HD G+ +F + L+++ Sbjct: 227 DINAVSFFPNGYAFATGSDDATCRLFDLRADQELLLYSHDNIICGITSVAFSKSGRLLLA 286 Query: 313 GADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCV 411 G DD +W + K L GH N VSC+ Sbjct: 287 GYDDFNCNVW--DTLKGDRAGVLAGHDNRVSCL 317
>GBLP_CAEEL (Q21215) Guanine nucleotide-binding protein beta subunit 2-like 1| Length = 324 Score = 45.8 bits (107), Expect = 6e-05 Identities = 41/160 (25%), Positives = 68/160 (42%), Gaps = 18/160 (11%) Frame = +1 Query: 31 VAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI--GALRKKTVSPADDIMRL--TQ 198 V LTGHNH+V +S S D+T+R+WD+ G ++ +S D++ + + Sbjct: 61 VRSLTGHNHFVSDVVISSDGQFALSGSWDKTLRLWDLNQGVSTRQFISHTKDVLSVAFSA 120 Query: 199 MNTDLFGG----------VDAVVKYVL--EGHDRGVNWASFHPTL--PLIVSGADDRQVK 336 N + G A KY + + H V+ F P+ P+IVS D+ VK Sbjct: 121 DNRQIVSGSRDKSIKLWNTLAQCKYTITDDCHTDWVSTVRFSPSNRDPVIVSAGWDKVVK 180 Query: 337 LWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 +W + + + GH V+ V + S +D Sbjct: 181 VWNLGNCRL--KTNHIGHTGYVNTVTVSPDGSLCASGGKD 218 Score = 43.5 bits (101), Expect = 3e-04 Identities = 39/143 (27%), Positives = 64/143 (44%), Gaps = 2/143 (1%) Frame = +1 Query: 40 LTGHNHYVMCASFHPKED--LVVSASLDQTVRVWDIGALRKKTVSPADDIMRLTQMNTDL 213 L GH +V + + + D V+S+S D+T+ VWD+ +V+P D+ Sbjct: 11 LEGHTGWVTQIATYTRNDKTTVLSSSRDKTILVWDV-----DSVAPVDE----------- 54 Query: 214 FGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVDTLRGHM 393 G + V+ L GH+ V+ +SG+ D+ ++LW +N + H Sbjct: 55 -GPIGRPVR-SLTGHNHFVSDVVISSDGQFALSGSWDKTLRLWDLN--QGVSTRQFISHT 110 Query: 394 NNVSCVMFHAKQDIIVSNSEDKA 462 +V V F A IVS S DK+ Sbjct: 111 KDVLSVAFSADNRQIVSGSRDKS 133 Score = 42.0 bits (97), Expect = 9e-04 Identities = 37/140 (26%), Positives = 56/140 (40%), Gaps = 20/140 (14%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 R+W+ H V+ +F +VS S D+++++W+ A K T++ DD Sbjct: 93 RLWDLNQGVSTRQFISHTKDVLSVAFSADNRQIVSGSRDKSIKLWNTLAQCKYTIT--DD 150 Query: 181 I-------MRLTQMNTD---LFGGVDAVVKYVLEG----------HDRGVNWASFHPTLP 300 +R + N D + G D VVK G H VN + P Sbjct: 151 CHTDWVSTVRFSPSNRDPVIVSAGWDKVVKVWNLGNCRLKTNHIGHTGYVNTVTVSPDGS 210 Query: 301 LIVSGADDRQVKLWRMNDTK 360 L SG D Q LW +N+ K Sbjct: 211 LCASGGKDGQAMLWDLNEGK 230 Score = 28.9 bits (63), Expect = 7.5 Identities = 14/62 (22%), Positives = 24/62 (38%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 ++WN + GH YV + P L S D +WD+ + P +D Sbjct: 180 KVWNLGNCRLKTNHIGHTGYVNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLPGND 239 Query: 181 IM 186 ++ Sbjct: 240 VI 241
>NLE1_MOUSE (Q8VEJ4) Notchless homolog 1| Length = 484 Score = 45.8 bits (107), Expect = 6e-05 Identities = 39/144 (27%), Positives = 60/144 (41%), Gaps = 1/144 (0%) Frame = +1 Query: 31 VAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDIMRLTQMNTD 210 +A +TGH + F P +V SAS D+++++WD G K S Sbjct: 364 LARMTGHQALINQVLFSPDSRIVASASFDKSIKLWD-GRTGKYLAS-------------- 408 Query: 211 LFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVDT-LRG 387 L GH V ++ L+VSG+ D +K+W D KA ++ T L G Sbjct: 409 ------------LRGHVAAVYQIAWSADSRLLVSGSSDSTLKVW---DVKAQKLATDLPG 453 Query: 388 HMNNVSCVMFHAKQDIIVSNSEDK 459 H + V V + + S +DK Sbjct: 454 HADEVYAVDWSPDGQRVASGGKDK 477 Score = 44.3 bits (103), Expect = 2e-04 Identities = 42/166 (25%), Positives = 69/166 (41%), Gaps = 22/166 (13%) Frame = +1 Query: 28 CVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKK-----------TVSPA 174 C + L GH+ V+ +F P + S S D TVR WD+ ++S + Sbjct: 105 CTSSLEGHSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISWS 164 Query: 175 DDIMRLTQ--MNTDLF---GGVDAVVKYVLEGHDR---GVNWASFH--PTLPLIVSGADD 324 D +L N + V L GH + G++W H P + S + D Sbjct: 165 PDGKKLASGCKNGQILLWDPSTGLQVGRTLTGHSKWITGLSWEPLHMNPECRYVASSSKD 224 Query: 325 RQVKLWRMNDTKAWEVD-TLRGHMNNVSCVMFHAKQDIIVSNSEDK 459 V++W DT A + L GH +V+C+ + ++ S S+D+ Sbjct: 225 GSVRVW---DTTAGRCERILTGHTQSVTCLRW-GGDGLLYSASQDR 266 Score = 42.7 bits (99), Expect = 5e-04 Identities = 45/169 (26%), Positives = 76/169 (44%), Gaps = 15/169 (8%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI-GALRKKTVSPAD 177 R+W+ + C +LTGH V C + + L+ SAS D+T++VW + +T+ Sbjct: 228 RVWDTTAGRCERILTGHTQSVTCLRW-GGDGLLYSASQDRTIKVWRAHDGVLCRTLQGHG 286 Query: 178 DIMRLTQMNTD------LFGGVDAVVK-YVLEGHDRGV-NWASFHPTL------PLIVSG 315 + ++TD F +A V L+G + + AS L +VSG Sbjct: 287 HWVNTMALSTDYALRTGAFEPAEATVNAQDLQGSLKELKERASSRYNLVRGQGPERLVSG 346 Query: 316 ADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSEDKA 462 +DD + LW + K + + GH ++ V+F I+ S S DK+ Sbjct: 347 SDDFTLFLWSPAEDKK-PLARMTGHQALINQVLFSPDSRIVASASFDKS 394 Score = 40.0 bits (92), Expect = 0.003 Identities = 30/115 (26%), Positives = 51/115 (44%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 ++W+ ++ +A L GH V ++ L+VS S D T++VWD+ A Sbjct: 396 KLWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKA----------- 444 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWR 345 ++ TDL G D V V+W+ P + SG D+ +++WR Sbjct: 445 ----QKLATDLPGHADEVY---------AVDWS---PDGQRVASGGKDKCLRIWR 483 Score = 35.4 bits (80), Expect = 0.080 Identities = 36/134 (26%), Positives = 53/134 (39%), Gaps = 8/134 (5%) Frame = +1 Query: 13 WQSRTCVAV---LTGHNHYVMCASFHPKE-----DLVVSASLDQTVRVWDIGALRKKTVS 168 W T + V LTGH+ ++ S+ P V S+S D +VRVWD A R Sbjct: 182 WDPSTGLQVGRTLTGHSKWITGLSWEPLHMNPECRYVASSSKDGSVRVWDTTAGR----- 236 Query: 169 PADDIMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRM 348 + +L GH + V + L+ S + DR +K+WR Sbjct: 237 ----------------------CERILTGHTQSVTCLRWGGD-GLLYSASQDRTIKVWRA 273 Query: 349 NDTKAWEVDTLRGH 390 +D TL+GH Sbjct: 274 HDGVLCR--TLQGH 285
>GBB4_RAT (O35353) Guanine nucleotide-binding protein beta subunit 4| (Transducin beta chain 4) Length = 339 Score = 45.8 bits (107), Expect = 6e-05 Identities = 39/153 (25%), Positives = 63/153 (41%), Gaps = 17/153 (11%) Frame = +1 Query: 4 IWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI--GALRKKTVSPAD 177 +W+ ++ TGH+ VM S P VS + D + ++WDI G R+ Sbjct: 167 LWDIETGQQTTTFTGHSGDVMSLSLSPDLKTFVSGACDASSKLWDIRDGMCRQSFTGHIS 226 Query: 178 DIMRLTQMNTD---LFGGVDAVVK---------YVLEGHDR---GVNWASFHPTLPLIVS 312 DI ++ + G DA + +L HD G+ +F + L+++ Sbjct: 227 DINAVSFFPSGYAFATGSDDATCRLFDLRADQELLLYSHDNIICGITSVAFSKSGRLLLA 286 Query: 313 GADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCV 411 G DD +W + K L GH N VSC+ Sbjct: 287 GYDDFNCSVW--DALKGGRAGVLAGHDNRVSCL 317
>NLE1_BOVIN (Q58D20) Notchless homolog 1| Length = 485 Score = 45.8 bits (107), Expect = 6e-05 Identities = 38/144 (26%), Positives = 60/144 (41%), Gaps = 1/144 (0%) Frame = +1 Query: 31 VAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDIMRLTQMNTD 210 +A +TGH + F P ++ SAS D+++++WD G K S Sbjct: 365 LARMTGHQALINQVVFSPDSRVIASASFDKSIKLWD-GRTGKYLAS-------------- 409 Query: 211 LFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVDT-LRG 387 L GH V ++ L+VSG+ D +K+W D KA ++ T L G Sbjct: 410 ------------LRGHVAAVYQIAWSADSRLLVSGSSDSTLKVW---DVKAQKLSTDLPG 454 Query: 388 HMNNVSCVMFHAKQDIIVSNSEDK 459 H + V V + + S +DK Sbjct: 455 HADEVYAVDWSPDGQRVASGGKDK 478 Score = 45.1 bits (105), Expect = 1e-04 Identities = 43/166 (25%), Positives = 71/166 (42%), Gaps = 22/166 (13%) Frame = +1 Query: 28 CVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKK-----------TVSPA 174 C + L GH+ V+ +F P + S S D TVR WD+ ++S + Sbjct: 106 CTSSLEGHSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHFTCQGHRHWVLSISWS 165 Query: 175 DDIMRLTQ--MNTDLFGGVDAVVKYV---LEGHDR---GVNWASFH--PTLPLIVSGADD 324 D +L N + + K V L GH + ++W H P + S + D Sbjct: 166 PDGKKLASGCKNGQILLWDPSTGKQVGRALTGHSKWITALSWEPLHANPECRYVASSSKD 225 Query: 325 RQVKLWRMNDTKAWEVD-TLRGHMNNVSCVMFHAKQDIIVSNSEDK 459 V++W DT A + TL GH +V+C+ + ++ S S+D+ Sbjct: 226 GSVRVW---DTTAGRCERTLTGHAQSVTCLRW-GGDGLLYSASQDR 267 Score = 41.2 bits (95), Expect = 0.001 Identities = 30/115 (26%), Positives = 52/115 (45%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 ++W+ ++ +A L GH V ++ L+VS S D T++VWD+ A Sbjct: 397 KLWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKA----------- 445 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWR 345 +++TDL G D V V+W+ P + SG D+ +++WR Sbjct: 446 ----QKLSTDLPGHADEVY---------AVDWS---PDGQRVASGGKDKCLRIWR 484 Score = 40.8 bits (94), Expect = 0.002 Identities = 45/180 (25%), Positives = 72/180 (40%), Gaps = 26/180 (14%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIG------------ 144 R+W+ + C LTGH V C + + L+ SAS D+T++VW Sbjct: 229 RVWDTTAGRCERTLTGHAQSVTCLRW-GGDGLLYSASQDRTIKVWRAHDGVLCRTLQGHG 287 Query: 145 ------------ALRKKTVSPADDIMRLTQMNTDLFGGVDAVVKYVLEGHD--RGVNWAS 282 ALR PA+ + DL G + + + L ++ RG Sbjct: 288 HWVNTMALSTDYALRTGAFEPAEASVNA----QDLRGSLQELKERALSRYNLVRGQG--- 340 Query: 283 FHPTLPLIVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSEDKA 462 +VSG+DD + LW + K + + GH ++ V+F +I S S DK+ Sbjct: 341 ----PERLVSGSDDFTLFLWSPAEDKK-PLARMTGHQALINQVVFSPDSRVIASASFDKS 395
>PWP2_HUMAN (Q15269) Periodic tryptophan protein 2 homolog| Length = 919 Score = 45.8 bits (107), Expect = 6e-05 Identities = 32/136 (23%), Positives = 59/136 (43%), Gaps = 17/136 (12%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 ++WN S C T H+ V +F +VV++S+D TVR +D+ R + Sbjct: 398 KVWNTLSGFCFVTFTEHSSGVTGVTFTATGYVVVTSSMDGTVRAFDLHRYRNFRTFTSPR 457 Query: 181 IMRLTQMNTDLFGGVDAV-----------------VKYVLEGHDRGVNWASFHPTLPLIV 309 + + + D G + + + VL GH+ ++ F+P ++ Sbjct: 458 PTQFSCVAVDASGEIVSAGAQDSFEIFVWSMQTGRLLDVLSGHEGPISGLCFNPMKSVLA 517 Query: 310 SGADDRQVKLWRMNDT 357 S + D+ V+LW M D+ Sbjct: 518 SASWDKTVRLWDMFDS 533 Score = 42.7 bits (99), Expect = 5e-04 Identities = 21/66 (31%), Positives = 39/66 (59%), Gaps = 2/66 (3%) Frame = +1 Query: 4 IWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI--GALRKKTVSPAD 177 +W+ Q+ + VL+GH + F+P + ++ SAS D+TVR+WD+ K+T++ Sbjct: 485 VWSMQTGRLLDVLSGHEGPISGLCFNPMKSVLASASWDKTVRLWDMFDSWRTKETLALTS 544 Query: 178 DIMRLT 195 D + +T Sbjct: 545 DALAVT 550 Score = 39.3 bits (90), Expect = 0.006 Identities = 37/169 (21%), Positives = 71/169 (42%), Gaps = 17/169 (10%) Frame = +1 Query: 4 IWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI--GALRKKTVSPAD 177 +W WQS + V GH + ++ ++ P +V+ D V+VW+ G + Sbjct: 357 VWEWQSESYVLKQQGHFNSMVALAYSPDGQYIVTGGDDGKVKVWNTLSGFCFVTFTEHSS 416 Query: 178 DIMRLTQMNTD---LFGGVDAVVK-YVLEGHDRGVNWASFHPTL----------PLIVSG 315 + +T T + +D V+ + L + + S PT ++ +G Sbjct: 417 GVTGVTFTATGYVVVTSSMDGTVRAFDLHRYRNFRTFTSPRPTQFSCVAVDASGEIVSAG 476 Query: 316 ADDR-QVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSEDK 459 A D ++ +W M + +D L GH +S + F+ + ++ S S DK Sbjct: 477 AQDSFEIFVWSMQTGRL--LDVLSGHEGPISGLCFNPMKSVLASASWDK 523 Score = 35.4 bits (80), Expect = 0.080 Identities = 24/74 (32%), Positives = 38/74 (51%), Gaps = 2/74 (2%) Frame = +1 Query: 241 YVL--EGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVM 414 YVL +GH + ++ P IV+G DD +VK+W N + T H + V+ V Sbjct: 365 YVLKQQGHFNSMVALAYSPDGQYIVTGGDDGKVKVW--NTLSGFCFVTFTEHSSGVTGVT 422 Query: 415 FHAKQDIIVSNSED 456 F A ++V++S D Sbjct: 423 FTATGYVVVTSSMD 436
>WDR16_MACFA (Q95JL5) WD-repeat protein 16| Length = 571 Score = 45.8 bits (107), Expect = 6e-05 Identities = 43/171 (25%), Positives = 67/171 (39%), Gaps = 17/171 (9%) Frame = +1 Query: 1 RIWN--WQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPA 174 R+W Q++ L H V C + V+AS D T +WD+ LR+ + A Sbjct: 393 RVWQIGCQTQKLEEALKEHKSSVSCIRVKKNNEECVTASTDGTCIIWDLVRLRRNQMILA 452 Query: 175 DDIMRLTQMNTDLF----GGVDAVVKY----------VLEGHDRG-VNWASFHPTLPLIV 309 + + + + + F G D + Y LEG G +N V Sbjct: 453 NTLFQCVCYHPEEFQIITSGTDRKIAYWEVFDGTVIRELEGSLSGSINGMDITQEGVHFV 512 Query: 310 SGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSEDKA 462 +G +D VK+W N+ + V GH N++ + IVS S D A Sbjct: 513 TGGNDHLVKVWDYNEGEVTHVGV--GHSGNITRIRISPGNQYIVSVSADGA 561 Score = 29.3 bits (64), Expect = 5.7 Identities = 12/51 (23%), Positives = 27/51 (52%) Frame = +1 Query: 304 IVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 ++SG + +V++W++ + L+ H ++VSC+ + V+ S D Sbjct: 383 VISGGGEGEVRVWQIGCQTQKLEEALKEHKSSVSCIRVKKNNEECVTASTD 433
>GRWD1_HUMAN (Q9BQ67) Glutamate-rich WD repeat-containing protein 1| Length = 446 Score = 45.8 bits (107), Expect = 6e-05 Identities = 36/137 (26%), Positives = 56/137 (40%), Gaps = 2/137 (1%) Frame = +1 Query: 46 GHNHYVMCASFHPKEDLV-VSASLDQTVRVWDIGALRKKTVSPADDIMRLTQMNTDLFGG 222 GH V + P E+ V S S D ++R+WDI A K Sbjct: 259 GHTRSVEDLQWSPTENTVFASCSADASIRIWDIRAAPSK--------------------- 297 Query: 223 VDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWE-VDTLRGHMNN 399 A + HD VN S+ P ++SG DD +K+W + K+ V T + H+ Sbjct: 298 --ACMLTTATAHDGDVNVISWSRREPFLLSGGDDGALKIWDLRQFKSGSPVATFKQHVAP 355 Query: 400 VSCVMFHAKQDIIVSNS 450 V+ V +H + + + S Sbjct: 356 VTSVEWHPQDSGVFAAS 372
>WDR16_HUMAN (Q8N1V2) WD-repeat protein 16 (WD40-repeat protein up-regulated in| HCC) Length = 620 Score = 45.4 bits (106), Expect = 8e-05 Identities = 43/171 (25%), Positives = 67/171 (39%), Gaps = 17/171 (9%) Frame = +1 Query: 1 RIWN--WQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPA 174 R+W Q++ L H V C + V+AS D T +WD+ LR+ + A Sbjct: 442 RVWQIGCQTQKLEEALKEHKSSVSCIRVKRNNEECVTASTDGTCIIWDLVRLRRNQMILA 501 Query: 175 DDIMRLTQMNTDLF----GGVDAVVKY----------VLEGHDRG-VNWASFHPTLPLIV 309 + + + + + F G D + Y LEG G +N V Sbjct: 502 NTLFQCVCYHPEEFQIITSGTDRKIAYWEVFDGTVIRELEGSLSGSINGMDITQEGVHFV 561 Query: 310 SGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSEDKA 462 +G +D VK+W N+ + V GH N++ + IVS S D A Sbjct: 562 TGGNDHLVKVWDYNEGEVTHVGV--GHSGNITRIRISPGNQYIVSVSADGA 610 Score = 29.6 bits (65), Expect = 4.4 Identities = 17/73 (23%), Positives = 34/73 (46%), Gaps = 1/73 (1%) Frame = +1 Query: 241 YVLEG-HDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMF 417 YV+ H GV + ++SG + +V++W++ + L+ H ++VSC+ Sbjct: 410 YVINNAHRIGVTAIATTSDCKRVISGGGEGEVRVWQIGCQTQKLEEALKEHKSSVSCIRV 469 Query: 418 HAKQDIIVSNSED 456 + V+ S D Sbjct: 470 KRNNEECVTASTD 482
>UTP13_SCHPO (Q9USN3) Probable U3 small nucleolar RNA-associated protein 13 (U3| snoRNA-associated protein 13) Length = 777 Score = 45.4 bits (106), Expect = 8e-05 Identities = 37/152 (24%), Positives = 60/152 (39%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 ++W+ + V VL GH V SF+P + S S D+T+R+W++ D Sbjct: 490 KLWDSSTGEVVGVLRGHRRGVWACSFNPFSRQLASGSGDRTIRIWNV------------D 537 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTK 360 + Q LEGH + + +VS A D VK+W ++ + Sbjct: 538 TQQCVQ---------------TLEGHTGAILKLIYISQGTQVVSAAADGLVKVWSLSSGE 582 Query: 361 AWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 V TL H + V + ++VS D Sbjct: 583 C--VATLDNHEDRVWALASRFDGSLLVSGGAD 612 Score = 45.4 bits (106), Expect = 8e-05 Identities = 41/163 (25%), Positives = 66/163 (40%), Gaps = 10/163 (6%) Frame = +1 Query: 1 RIWNWQSRT----CVAVLTGHNHYVMCASFHPKE-----DLVVSASLDQTVRVWDIGALR 153 R+WN C+ V TGH V + P + + S+S D+T++ +++G+ Sbjct: 389 RLWNLNIEDNVYKCIHVFTGHTASVTAVALGPLDVNGYPTFLASSSQDRTLKRFNLGS-- 446 Query: 154 KKTVSPADDIMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQV 333 Q+N F + ++ HDR VN +I S + D+ + Sbjct: 447 --------------QLNKSDFSNRAV---WTIKAHDRDVNAIQVSKDGRIIASASQDKTI 489 Query: 334 KLWRMNDTKAWE-VDTLRGHMNNVSCVMFHAKQDIIVSNSEDK 459 KLW D+ E V LRGH V F+ + S S D+ Sbjct: 490 KLW---DSSTGEVVGVLRGHRRGVWACSFNPFSRQLASGSGDR 529 Score = 43.1 bits (100), Expect = 4e-04 Identities = 32/142 (22%), Positives = 55/142 (38%), Gaps = 2/142 (1%) Frame = +1 Query: 40 LTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDIMRLTQMNTDLFG 219 + H V+ + P L+ + + V+VWDI Sbjct: 99 MKAHETPVITMTIDPTNTLLATGGAEGLVKVWDIAG------------------------ 134 Query: 220 GVDAVVKYVLEGHDRGVNWASF--HPTLPLIVSGADDRQVKLWRMNDTKAWEVDTLRGHM 393 A V + GH ++ F H ++ SGADD +V+LW +N +++ V GH Sbjct: 135 ---AYVTHSFRGHGGVISALCFGKHQNTWVLASGADDSRVRLWDLNSSRSMAV--FEGHS 189 Query: 394 NNVSCVMFHAKQDIIVSNSEDK 459 + + + F ++S S DK Sbjct: 190 SVIRGLTFEPTGSFLLSGSRDK 211 Score = 40.4 bits (93), Expect = 0.002 Identities = 17/47 (36%), Positives = 28/47 (59%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI 141 R+W+ S +AV GH+ + +F P ++S S D+TV+VW+I Sbjct: 172 RLWDLNSSRSMAVFEGHSSVIRGLTFEPTGSFLLSGSRDKTVQVWNI 218 Score = 38.1 bits (87), Expect = 0.012 Identities = 25/123 (20%), Positives = 45/123 (36%), Gaps = 2/123 (1%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYV--MCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPA 174 ++W+ GH + +C H ++ S + D VR+WD+ + R V Sbjct: 128 KVWDIAGAYVTHSFRGHGGVISALCFGKHQNTWVLASGADDSRVRLWDLNSSRSMAV--- 184 Query: 175 DDIMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMND 354 EGH + +F PT ++SG+ D+ V++W + Sbjct: 185 ------------------------FEGHSSVIRGLTFEPTGSFLLSGSRDKTVQVWNIKK 220 Query: 355 TKA 363 A Sbjct: 221 RSA 223 Score = 31.6 bits (70), Expect = 1.2 Identities = 15/45 (33%), Positives = 20/45 (44%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVW 135 ++W+ S CVA L H V + L+VS D V VW Sbjct: 574 KVWSLSSGECVATLDNHEDRVWALASRFDGSLLVSGGADAVVSVW 618
>POP1_SCHPO (P87060) WD-repeat protein pop1| Length = 775 Score = 45.4 bits (106), Expect = 8e-05 Identities = 35/120 (29%), Positives = 52/120 (43%) Frame = +1 Query: 91 DLVVSASLDQTVRVWDIGALRKKTVSPADDIMRLTQMNTDLFGGVDAVVKYVLEGHDRGV 270 DL+VSAS D T+RVW V +VL GH V Sbjct: 588 DLIVSASYDGTLRVWKAST---------------------------GVCLHVLRGHVGRV 620 Query: 271 NWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNS 450 + +P+ +S D ++++W + + + TL GH N VS V F+ Q+I+VS S Sbjct: 621 YSVTINPSRQQCISAGTDAKIRIWNLESGEL--LQTLHGHSNLVSQVTFN--QNILVSAS 676 Score = 39.7 bits (91), Expect = 0.004 Identities = 23/117 (19%), Positives = 44/117 (37%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 R+W + C+ VL GH V + +P +SA D +R+W++ + Sbjct: 600 RVWKASTGVCLHVLRGHVGRVYSVTINPSRQQCISAGTDAKIRIWNLES----------- 648 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMN 351 + L GH V+ +F+ + + S D +++W +N Sbjct: 649 ----------------GELLQTLHGHSNLVSQVTFNQNILVSASAPPDTSLRVWDLN 689 Score = 34.3 bits (77), Expect = 0.18 Identities = 47/179 (26%), Positives = 74/179 (41%), Gaps = 27/179 (15%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTV----S 168 RI + ++T V + + H +F D +V+ S D+TVRVWD+ K V + Sbjct: 427 RINIYDTKTGVLIRSLEEHEGDVWTFEYVGDTLVTGSTDRTVRVWDLRTGECKQVFYGHT 486 Query: 169 PADDIMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRM 348 +++ Q N D V + + N A+ P P I+S + D ++LW + Sbjct: 487 STIRCIKIVQGNQSTTDTDD-----VEKENRPASNDANSMP--PYIISSSRDCTIRLWSL 539 Query: 349 ------------------ND-----TKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 ND T + + TLRGH ++V V D+IVS S D Sbjct: 540 PCLDDPPFVNVNENPDQNNDFTSATTNPFYIRTLRGHTDSVREVA--CLGDLIVSASYD 596
>GBLP_DROME (O18640) Guanine nucleotide-binding protein beta subunit-like| protein (Receptor of activated protein kinase C homolog) Length = 318 Score = 45.4 bits (106), Expect = 8e-05 Identities = 40/142 (28%), Positives = 58/142 (40%), Gaps = 2/142 (1%) Frame = +1 Query: 40 LTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDIMRLTQMNTDLFG 219 L GH+H++ + +S S DQT+R+WD+ A KT Sbjct: 60 LYGHSHFISDVVLSSDGNYALSGSWDQTLRLWDLAA--GKTTRR---------------- 101 Query: 220 GVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVDTLRGHMNN 399 EGH + V +F IVSG+ D+ +KLW + + GH + Sbjct: 102 ---------FEGHTKDVLSVAFSADNRQIVSGSRDKTIKLWNTLAECKFTIQE-DGHTDW 151 Query: 400 VSCVMF--HAKQDIIVSNSEDK 459 VSCV F + IIVS D+ Sbjct: 152 VSCVRFSPNHSNPIIVSCGWDR 173 Score = 41.6 bits (96), Expect = 0.001 Identities = 40/141 (28%), Positives = 60/141 (42%), Gaps = 1/141 (0%) Frame = +1 Query: 40 LTGHNHYVMCASFHPKE-DLVVSASLDQTVRVWDIGALRKKTVSPADDIMRLTQMNTDLF 216 L GHN +V + +PK+ D ++SAS D+T+ VW + D+ L+ Sbjct: 11 LIGHNGWVTQIATNPKDPDTIISASRDKTLIVWKL---------TRDEDTNYGYPQKRLY 61 Query: 217 GGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVDTLRGHMN 396 G + VL N+A +SG+ D+ ++LW + K GH Sbjct: 62 GHSHFISDVVLSSDG---NYA---------LSGSWDQTLRLWDLAAGKTTR--RFEGHTK 107 Query: 397 NVSCVMFHAKQDIIVSNSEDK 459 +V V F A IVS S DK Sbjct: 108 DVLSVAFSADNRQIVSGSRDK 128 Score = 40.8 bits (94), Expect = 0.002 Identities = 29/123 (23%), Positives = 46/123 (37%), Gaps = 3/123 (2%) Frame = +1 Query: 1 RIWNWQSRTCVAVLT-GHNHYVMCASFHPKED--LVVSASLDQTVRVWDIGALRKKTVSP 171 ++WN + + GH +V C F P ++VS D+TV+VW++ + K Sbjct: 131 KLWNTLAECKFTIQEDGHTDWVSCVRFSPNHSNPIIVSCGWDRTVKVWNLANCKLKNNH- 189 Query: 172 ADDIMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMN 351 GH+ +N + P L SG D + LW +N Sbjct: 190 --------------------------HGHNGYLNTVTVSPDGSLCTSGGKDSKALLWDLN 223 Query: 352 DTK 360 D K Sbjct: 224 DGK 226
>NLE1_PONPY (Q5RFF8) Notchless homolog 1| Length = 484 Score = 45.4 bits (106), Expect = 8e-05 Identities = 43/166 (25%), Positives = 71/166 (42%), Gaps = 22/166 (13%) Frame = +1 Query: 28 CVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKK-----------TVSPA 174 C + L GH+ V+ +F P + S S D TVR WD+ ++S + Sbjct: 105 CTSSLEGHSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISWS 164 Query: 175 DDIMRLTQ--MNTDLFGGVDAVVKYV---LEGHDR---GVNWASFH--PTLPLIVSGADD 324 D +L N + + K V L GH + G++W H P + S + D Sbjct: 165 PDGKKLASGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHANPECRYVASSSKD 224 Query: 325 RQVKLWRMNDTKAWEVD-TLRGHMNNVSCVMFHAKQDIIVSNSEDK 459 V++W DT A + L GH +V+C+ + ++ S S+D+ Sbjct: 225 GSVRIW---DTTAGRCERILTGHTQSVTCLRW-GGDGLLYSASQDR 266 Score = 43.5 bits (101), Expect = 3e-04 Identities = 46/180 (25%), Positives = 73/180 (40%), Gaps = 26/180 (14%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIG------------ 144 RIW+ + C +LTGH V C + + L+ SAS D+T++VW Sbjct: 228 RIWDTTAGRCERILTGHTQSVTCLRW-GGDGLLYSASQDRTIKVWRAHDGVLCRTLQGHG 286 Query: 145 ------------ALRKKTVSPADDIMRLTQMNTDLFGGVDAVVKYVLEGHD--RGVNWAS 282 ALR PA+ + DL G + + + L ++ RG Sbjct: 287 HWVNTMALSTDYALRTGAFEPAEASVN----PQDLQGSLQELKERALSRYNLMRGQG--- 339 Query: 283 FHPTLPLIVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSEDKA 462 +VSG+DD + LW + K + + GH ++ V+F I+ S S DK+ Sbjct: 340 ----PERLVSGSDDFTLFLWSPAEDKK-PLTRMTGHQALINQVLFSPDSRIVASASFDKS 394 Score = 42.7 bits (99), Expect = 5e-04 Identities = 37/141 (26%), Positives = 57/141 (40%), Gaps = 1/141 (0%) Frame = +1 Query: 40 LTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDIMRLTQMNTDLFG 219 +TGH + F P +V SAS D+++++WD G K S Sbjct: 367 MTGHQALINQVLFSPDSRIVASASFDKSIKLWD-GRTGKYLAS----------------- 408 Query: 220 GVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVD-TLRGHMN 396 L GH V ++ L+VSG+ D +K+W D KA ++ L GH + Sbjct: 409 ---------LRGHVAAVYQIAWSADSRLLVSGSSDSTLKVW---DVKAQKLAMDLPGHAD 456 Query: 397 NVSCVMFHAKQDIIVSNSEDK 459 V V + + S +DK Sbjct: 457 EVYAVDWSPDGQRVASGGKDK 477 Score = 37.7 bits (86), Expect = 0.016 Identities = 29/115 (25%), Positives = 50/115 (43%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 ++W+ ++ +A L GH V ++ L+VS S D T++VWD+ A Sbjct: 396 KLWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKA----------- 444 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWR 345 ++ DL G D V V+W+ P + SG D+ +++WR Sbjct: 445 ----QKLAMDLPGHADEVY---------AVDWS---PDGQRVASGGKDKCLRIWR 483 Score = 32.7 bits (73), Expect = 0.52 Identities = 31/122 (25%), Positives = 48/122 (39%), Gaps = 5/122 (4%) Frame = +1 Query: 40 LTGHNHYVMCASFHPKED-----LVVSASLDQTVRVWDIGALRKKTVSPADDIMRLTQMN 204 L GH+ ++ S+ P V S+S D +VR+WD A R Sbjct: 194 LAGHSKWITGLSWEPLHANPECRYVASSSKDGSVRIWDTTAGR----------------- 236 Query: 205 TDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVDTLR 384 + +L GH + V + L+ S + DR +K+WR +D TL+ Sbjct: 237 ----------CERILTGHTQSVTCLRWGGD-GLLYSASQDRTIKVWRAHDGVLCR--TLQ 283 Query: 385 GH 390 GH Sbjct: 284 GH 285
>NLE1_HUMAN (Q9NVX2) Notchless homolog 1| Length = 484 Score = 45.4 bits (106), Expect = 8e-05 Identities = 43/166 (25%), Positives = 71/166 (42%), Gaps = 22/166 (13%) Frame = +1 Query: 28 CVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKK-----------TVSPA 174 C + L GH+ V+ +F P + S S D TVR WD+ ++S + Sbjct: 105 CTSSLEGHSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISWS 164 Query: 175 DDIMRLTQ--MNTDLFGGVDAVVKYV---LEGHDR---GVNWASFH--PTLPLIVSGADD 324 D +L N + + K V L GH + G++W H P + S + D Sbjct: 165 PDGKKLASGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHANPECRYVASSSKD 224 Query: 325 RQVKLWRMNDTKAWEVD-TLRGHMNNVSCVMFHAKQDIIVSNSEDK 459 V++W DT A + L GH +V+C+ + ++ S S+D+ Sbjct: 225 GSVRIW---DTTAGRCERILTGHTQSVTCLRW-GGDGLLYSASQDR 266 Score = 43.5 bits (101), Expect = 3e-04 Identities = 46/180 (25%), Positives = 73/180 (40%), Gaps = 26/180 (14%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIG------------ 144 RIW+ + C +LTGH V C + + L+ SAS D+T++VW Sbjct: 228 RIWDTTAGRCERILTGHTQSVTCLRW-GGDGLLYSASQDRTIKVWRAHDGVLCRTLQGHG 286 Query: 145 ------------ALRKKTVSPADDIMRLTQMNTDLFGGVDAVVKYVLEGHD--RGVNWAS 282 ALR PA+ + DL G + + + L ++ RG Sbjct: 287 HWVNTMALSTDYALRTGAFEPAEASVN----PQDLQGSLQELKERALSRYNLVRGQG--- 339 Query: 283 FHPTLPLIVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSEDKA 462 +VSG+DD + LW + K + + GH ++ V+F I+ S S DK+ Sbjct: 340 ----PERLVSGSDDFTLFLWSPAEDKK-PLTRMTGHQALINQVLFSPDSRIVASASFDKS 394 Score = 42.7 bits (99), Expect = 5e-04 Identities = 37/141 (26%), Positives = 57/141 (40%), Gaps = 1/141 (0%) Frame = +1 Query: 40 LTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDIMRLTQMNTDLFG 219 +TGH + F P +V SAS D+++++WD G K S Sbjct: 367 MTGHQALINQVLFSPDSRIVASASFDKSIKLWD-GRTGKYLAS----------------- 408 Query: 220 GVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVD-TLRGHMN 396 L GH V ++ L+VSG+ D +K+W D KA ++ L GH + Sbjct: 409 ---------LRGHVAAVYQIAWSADSRLLVSGSSDSTLKVW---DVKAQKLAMDLPGHAD 456 Query: 397 NVSCVMFHAKQDIIVSNSEDK 459 V V + + S +DK Sbjct: 457 EVYAVDWSPDGQRVASGGKDK 477 Score = 37.7 bits (86), Expect = 0.016 Identities = 29/115 (25%), Positives = 50/115 (43%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 ++W+ ++ +A L GH V ++ L+VS S D T++VWD+ A Sbjct: 396 KLWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKA----------- 444 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWR 345 ++ DL G D V V+W+ P + SG D+ +++WR Sbjct: 445 ----QKLAMDLPGHADEVY---------AVDWS---PDGQRVASGGKDKCLRIWR 483 Score = 32.7 bits (73), Expect = 0.52 Identities = 31/122 (25%), Positives = 48/122 (39%), Gaps = 5/122 (4%) Frame = +1 Query: 40 LTGHNHYVMCASFHPKED-----LVVSASLDQTVRVWDIGALRKKTVSPADDIMRLTQMN 204 L GH+ ++ S+ P V S+S D +VR+WD A R Sbjct: 194 LAGHSKWITGLSWEPLHANPECRYVASSSKDGSVRIWDTTAGR----------------- 236 Query: 205 TDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVDTLR 384 + +L GH + V + L+ S + DR +K+WR +D TL+ Sbjct: 237 ----------CERILTGHTQSVTCLRWGGD-GLLYSASQDRTIKVWRAHDGVLCR--TLQ 283 Query: 385 GH 390 GH Sbjct: 284 GH 285
>WDR71_HUMAN (Q9BRP4) WD-repeat protein 71 (Protein G-16)| Length = 392 Score = 45.1 bits (105), Expect = 1e-04 Identities = 36/138 (26%), Positives = 53/138 (38%), Gaps = 2/138 (1%) Frame = +1 Query: 49 HNHYVMCASFHPKEDLVVSASLDQTVRVWDI--GALRKKTVSPADDIMRLTQMNTDLFGG 222 H + C + L VS+S D T+++W G LR+ Sbjct: 91 HTKSITCLDISSRGGLGVSSSTDGTMKIWQASNGELRR---------------------- 128 Query: 223 VDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNV 402 VLEGH VN F P+ +++SG D Q+K+W D V T +GH + Sbjct: 129 -------VLEGHVFDVNCCRFFPSGLVVLSGGMDAQLKIWSAEDASC--VVTFKGHKGGI 179 Query: 403 SCVMFHAKQDIIVSNSED 456 + +VS S D Sbjct: 180 LDTAIVDRGRNVVSASRD 197 Score = 38.1 bits (87), Expect = 0.012 Identities = 17/48 (35%), Positives = 26/48 (54%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIG 144 +IW+ + +CV GH ++ + + VVSAS D T R+WD G Sbjct: 159 KIWSAEDASCVVTFKGHKGGILDTAIVDRGRNVVSASRDGTARLWDCG 206 Score = 31.6 bits (70), Expect = 1.2 Identities = 14/45 (31%), Positives = 22/45 (48%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVW 135 +IW + VL GH V C F P +V+S +D +++W Sbjct: 117 KIWQASNGELRRVLEGHVFDVNCCRFFPSGLVVLSGGMDAQLKIW 161
>HIRA_MOUSE (Q61666) HIRA protein (TUP1-like enhancer of split protein 1)| Length = 1015 Score = 45.1 bits (105), Expect = 1e-04 Identities = 34/126 (26%), Positives = 54/126 (42%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 ++ N + CV++L H+ VM ++ P + + S S+D TV +W Sbjct: 114 KLANVEQWRCVSILRSHSGDVMDVAWSPHDAWLASCSVDNTVVIW--------------- 158 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTK 360 N F + A L GH V ++ P I S ADDR +K+WR D Sbjct: 159 -------NAVKFPEILA----TLRGHSGLVKGLTWDPVGKYIASQADDRSLKVWRTLD-- 205 Query: 361 AWEVDT 378 W+++T Sbjct: 206 -WQLET 210
>CAF1B_HUMAN (Q13112) Chromatin assembly factor 1 subunit B (CAF-1 subunit B)| (Chromatin assembly factor I p60 subunit) (CAF-I 60 kDa subunit) (CAF-Ip60) (M-phase phosphoprotein 7) Length = 559 Score = 45.1 bits (105), Expect = 1e-04 Identities = 29/97 (29%), Positives = 46/97 (47%), Gaps = 21/97 (21%) Frame = +1 Query: 229 AVVKYV--LEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWE----------- 369 A+V+++ L H + VN F PT ++ SG DD + LW++ND K E Sbjct: 54 AIVEFLSNLARHTKAVNVVRFSPTGEILASGGDDAVILLWKVNDNKEPEQIAFQDEDEAQ 113 Query: 370 --------VDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 V TLRGH+ +V + + +++ S S D Sbjct: 114 LNKENWTVVKTLRGHLEDVYDICWATDGNLMASASVD 150 Score = 30.0 bits (66), Expect = 3.3 Identities = 17/52 (32%), Positives = 26/52 (50%) Frame = +1 Query: 10 NWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTV 165 NW T V L GH V + +L+ SAS+D T +WD+ +K ++ Sbjct: 118 NW---TVVKTLRGHLEDVYDICWATDGNLMASASVDNTAIIWDVSKGQKISI 166
>HIRA_HUMAN (P54198) HIRA protein (TUP1-like enhancer of split protein 1)| Length = 1017 Score = 45.1 bits (105), Expect = 1e-04 Identities = 34/126 (26%), Positives = 54/126 (42%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 ++ N + CV++L H+ VM ++ P + + S S+D TV +W Sbjct: 114 KLANVEQWRCVSILRNHSGDVMDVAWSPHDAWLASCSVDNTVVIW--------------- 158 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTK 360 N F + A L GH V ++ P I S ADDR +K+WR D Sbjct: 159 -------NAVKFPEILA----TLRGHSGLVKGLTWDPVGKYIASQADDRSLKVWRTLD-- 205 Query: 361 AWEVDT 378 W+++T Sbjct: 206 -WQLET 210
>GBB1_DROME (P26308) Guanine nucleotide-binding protein beta subunit 1| Length = 340 Score = 45.1 bits (105), Expect = 1e-04 Identities = 41/153 (26%), Positives = 64/153 (41%), Gaps = 17/153 (11%) Frame = +1 Query: 4 IWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI--GALRKKTVSPAD 177 +W+ ++ V GH VM S P+ VS + D + ++WDI G ++ Sbjct: 168 LWDIETGLQVTSFLGHTGDVMALSLAPQCKTFVSGACDASAKLWDIREGVCKQTFPGHES 227 Query: 178 DIMRLTQM-NTDLF--GGVDAVVK---------YVLEGHDR---GVNWASFHPTLPLIVS 312 DI +T N F G DA + + HD G+ +F + L+++ Sbjct: 228 DINAVTFFPNGQAFATGSDDATCRLFDIRADQELAMYSHDNIICGITSVAFSKSGRLLLA 287 Query: 313 GADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCV 411 G DD +W + KA L GH N VSC+ Sbjct: 288 GYDDFNCNVW--DTMKAERSGILAGHDNRVSCL 318
>PRP19_CAEEL (Q10051) PRP19/PSO4 homolog| Length = 492 Score = 45.1 bits (105), Expect = 1e-04 Identities = 40/170 (23%), Positives = 62/170 (36%), Gaps = 19/170 (11%) Frame = +1 Query: 4 IWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTV-----S 168 +++++ + GHN + HP +SAS D +RVW K + + Sbjct: 235 LYDYEKEQVMQTFKGHNKKINAVVLHPDNITAISASADSHIRVWSATDSSSKAIIDVHQA 294 Query: 169 PADDIMRLTQMN-------------TDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIV 309 P DI + +D+ G V G V+ FHP + Sbjct: 295 PVTDISLNASGDYILSASDDSYWAFSDIRSGKSLCKVSVEPGSQIAVHSIEFHPDGLIFG 354 Query: 310 SGADDRQVKLWRM-NDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 +GA D VK+W + N T A GH V + F + + SED Sbjct: 355 TGAADAVVKIWDLKNQTVA---AAFPGHTAAVRSIAFSENGYYLATGSED 401 Score = 37.7 bits (86), Expect = 0.016 Identities = 37/138 (26%), Positives = 58/138 (42%), Gaps = 18/138 (13%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGA---LRKKTVSP 171 R+W+ + A++ H V S + D ++SAS D DI + L K +V P Sbjct: 276 RVWSATDSSSKAIIDVHQAPVTDISLNASGDYILSASDDSYWAFSDIRSGKSLCKVSVEP 335 Query: 172 ADDI-MRLTQMNTD--LFG--GVDAVVKY----------VLEGHDRGVNWASFHPTLPLI 306 I + + + D +FG DAVVK GH V +F + Sbjct: 336 GSQIAVHSIEFHPDGLIFGTGAADAVVKIWDLKNQTVAAAFPGHTAAVRSIAFSENGYYL 395 Query: 307 VSGADDRQVKLWRMNDTK 360 +G++D +VKLW + K Sbjct: 396 ATGSEDGEVKLWDLRKLK 413 Score = 34.3 bits (77), Expect = 0.18 Identities = 16/73 (21%), Positives = 34/73 (46%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 +IW+ +++T A GH V +F + + S D V++WD+ L+ ++ Sbjct: 363 KIWDLKNQTVAAAFPGHTAAVRSIAFSENGYYLATGSEDGEVKLWDLRKLKNLKTFANEE 422 Query: 181 IMRLTQMNTDLFG 219 + ++ D+ G Sbjct: 423 KQPINSLSFDMTG 435
>GBLP_YEAST (P38011) Guanine nucleotide-binding protein beta subunit-like| protein (Receptor of activated protein kinase C 1) (RACK1) (Receptor for activated C kinase) Length = 318 Score = 45.1 bits (105), Expect = 1e-04 Identities = 40/160 (25%), Positives = 70/160 (43%), Gaps = 23/160 (14%) Frame = +1 Query: 46 GHNHYVMCASFHPKEDLVVSASLDQTVRVWDI--GALRKKTVSPADDIMRL---TQMNTD 210 GH+H V + +SAS D+T+R+WD+ G ++ V D+M + + + Sbjct: 62 GHSHIVQDCTLTADGAYALSASWDKTLRLWDVATGETYQRFVGHKSDVMSVDIDKKASMI 121 Query: 211 LFGGVDAVVKY---------VLEGHDRGVNWASFHPTLP---------LIVSGADDRQVK 336 + G D +K L GH+ +W S +P I+S +D+ VK Sbjct: 122 ISGSRDKTIKVWTIKGQCLATLLGHN---DWVSQVRVVPNEKADDDSVTIISAGNDKMVK 178 Query: 337 LWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 W +N + E D + GH +N++ + +I S +D Sbjct: 179 AWNLNQFQI-EADFI-GHNSNINTLTASPDGTLIASAGKD 216 Score = 43.5 bits (101), Expect = 3e-04 Identities = 34/141 (24%), Positives = 58/141 (41%), Gaps = 20/141 (14%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 R+W+ + GH VM K +++S S D+T++VW I T+ +D Sbjct: 89 RLWDVATGETYQRFVGHKSDVMSVDIDKKASMIISGSRDKTIKVWTIKGQCLATLLGHND 148 Query: 181 IMRLTQM----------NTDLFGGVDAVVK------YVLE----GHDRGVNWASFHPTLP 300 + ++ T + G D +VK + +E GH+ +N + P Sbjct: 149 WVSQVRVVPNEKADDDSVTIISAGNDKMVKAWNLNQFQIEADFIGHNSNINTLTASPDGT 208 Query: 301 LIVSGADDRQVKLWRMNDTKA 363 LI S D ++ LW + KA Sbjct: 209 LIASAGKDGEIMLWNLAAKKA 229 Score = 32.0 bits (71), Expect = 0.88 Identities = 17/65 (26%), Positives = 29/65 (44%), Gaps = 1/65 (1%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKK-TVSPAD 177 + WN A GHN + + P L+ SA D + +W++ A + T+S D Sbjct: 178 KAWNLNQFQIEADFIGHNSNINTLTASPDGTLIASAGKDGEIMLWNLAAKKAMYTLSAQD 237 Query: 178 DIMRL 192 ++ L Sbjct: 238 EVFSL 242
>GBB4_MOUSE (P29387) Guanine nucleotide-binding protein beta subunit 4| (Transducin beta chain 4) Length = 339 Score = 45.1 bits (105), Expect = 1e-04 Identities = 39/153 (25%), Positives = 63/153 (41%), Gaps = 17/153 (11%) Frame = +1 Query: 4 IWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI--GALRKKTVSPAD 177 +W+ ++ TGH+ VM S P VS + D + ++WDI G R+ Sbjct: 167 LWDIETGQQTTTFTGHSGDVMSLSLSPDLKTFVSGACDASSKLWDIRDGMCRQSFTGHIS 226 Query: 178 DIMRLTQMNTD---LFGGVDAVVK---------YVLEGHDR---GVNWASFHPTLPLIVS 312 DI ++ + G DA + +L HD G+ +F + L+++ Sbjct: 227 DINAVSFFPSGYAFATGSDDATCRLFDLRADQELLLYSHDNIICGITSVAFSKSGRLLLA 286 Query: 313 GADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCV 411 G DD +W + K L GH N VSC+ Sbjct: 287 GYDDFNCSVW--DALKGGRSGVLAGHDNRVSCL 317
>GBB3_CANFA (P79147) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 3 (Transducin beta chain 3) Length = 340 Score = 44.7 bits (104), Expect = 1e-04 Identities = 33/139 (23%), Positives = 54/139 (38%) Frame = +1 Query: 40 LTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDIMRLTQMNTDLFG 219 L+ H Y+ C F ++V S+ D T +WDI ++KT Sbjct: 139 LSAHTGYLSCCRFLDDNNIVTSSG-DTTCALWDIETGQQKT------------------- 178 Query: 220 GVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVDTLRGHMNN 399 V GH + P L +SGA D KLW + + + T GH ++ Sbjct: 179 --------VFVGHTGDCMSLAVSPDFKLFISGACDASAKLWDVREGTCRQ--TFTGHESD 228 Query: 400 VSCVMFHAKQDIIVSNSED 456 ++ + F + I + S+D Sbjct: 229 INAICFFPNGEAICTGSDD 247 Score = 43.9 bits (102), Expect = 2e-04 Identities = 34/152 (22%), Positives = 60/152 (39%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 ++W+ + TC TGH + F P + + + S D + R++D+ A ++ T + Sbjct: 209 KLWDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQELTAYSDES 268 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTK 360 I+ G+ +F + L+ +G DD +W + K Sbjct: 269 II-------------------------CGITSVAFSLSGRLLFAGYDDFNCNIW--DSMK 301 Query: 361 AWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 V L GH N VSC+ A + + S D Sbjct: 302 GERVGILSGHDNRVSCLGVTADGMAVATGSWD 333 Score = 28.9 bits (63), Expect = 7.5 Identities = 13/45 (28%), Positives = 22/45 (48%) Frame = +1 Query: 4 IWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWD 138 IW+ V +L+GH++ V C V + S D ++VW+ Sbjct: 296 IWDSMKGERVGILSGHDNRVSCLGVTADGMAVATGSWDSFLKVWN 340
>CDC4_CANAL (P53699) Cell division control protein 4| Length = 684 Score = 44.7 bits (104), Expect = 1e-04 Identities = 36/160 (22%), Positives = 66/160 (41%), Gaps = 18/160 (11%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASF----------------HPKEDLVVSASLDQTVRV 132 R+WN ++ C + GH + C P+ L+++ S D + V Sbjct: 388 RVWNMKTGQCTHIFRGHTSTIRCLDIIHPAVIGKNQDGEDIVFPEYPLLITGSRDHNIHV 447 Query: 133 WDIGALRKKTVSPADDIMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVS 312 W + V + D + + D + + VL GH + V S + +I+S Sbjct: 448 WKL-----PVVDDSQDYIETFEGEFD-----NPYLIAVLSGHTQSVRSISGYGN--IIIS 495 Query: 313 GADDRQVKLWRMNDTKAWEVDTLRGHMNNV--SCVMFHAK 426 G+ D V++W + D L+GH++ V + + FH+K Sbjct: 496 GSYDSTVRVWDLLD-DGHCTHVLQGHLDRVYSTAIDFHSK 534 Score = 39.7 bits (91), Expect = 0.004 Identities = 49/163 (30%), Positives = 71/163 (43%), Gaps = 22/163 (13%) Frame = +1 Query: 31 VAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI-----------GALRKKTVSPAD 177 +AVL+GH V S + ++++S S D TVRVWD+ G L + S A Sbjct: 473 IAVLSGHTQSVRSISGYG--NIIISGSYDSTVRVWDLLDDGHCTHVLQGHL-DRVYSTAI 529 Query: 178 DIMRLT------QMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLI----VSGADDR 327 D T N +++ +K VL GH AS L L+ VS A D Sbjct: 530 DFHSKTCFSGSMDSNINVWNFETGELKKVLVGH------ASLVGLLDLVDDVLVSAAADA 583 Query: 328 QVKLWRMNDTKAWEV-DTLRGHMNNVSCVMFHAKQDIIVSNSE 453 +++W D K E+ L+GH ++C F +VS SE Sbjct: 584 TLRIW---DAKTGELRSKLKGHGAAITC--FEHDGLRVVSGSE 621 Score = 36.2 bits (82), Expect = 0.047 Identities = 29/134 (21%), Positives = 59/134 (44%), Gaps = 2/134 (1%) Frame = +1 Query: 4 IWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDI 183 I++ Q+ + VL GH V + + +V+ S D+TVRVW++ Sbjct: 349 IYSTQTGQLMKVLEGHEGGVWALKY--TGNTLVTGSTDRTVRVWNM---------KTGQC 397 Query: 184 MRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMN--DT 357 + + +T +D + V+ + G + P PL+++G+ D + +W++ D Sbjct: 398 THIFRGHTSTIRCLDIIHPAVIGKNQDGED--IVFPEYPLLITGSRDHNIHVWKLPVVDD 455 Query: 358 KAWEVDTLRGHMNN 399 ++T G +N Sbjct: 456 SQDYIETFEGEFDN 469 Score = 30.4 bits (67), Expect = 2.6 Identities = 35/132 (26%), Positives = 54/132 (40%), Gaps = 16/132 (12%) Frame = +1 Query: 1 RIWNW-QSRTCVAVLTGH--NHYVMCASFHPKEDLVVSASLDQTVRVW--DIGALRKKTV 165 R+W+ C VL GH Y FH K S S+D + VW + G L+K V Sbjct: 503 RVWDLLDDGHCTHVLQGHLDRVYSTAIDFHSKT--CFSGSMDSNINVWNFETGELKKVLV 560 Query: 166 SPA---------DDIMRLTQMNTDL--FGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVS 312 A DD++ + L + ++ L+GH G F +VS Sbjct: 561 GHASLVGLLDLVDDVLVSAAADATLRIWDAKTGELRSKLKGH--GAAITCFEHDGLRVVS 618 Query: 313 GADDRQVKLWRM 348 G+ ++ +KLW + Sbjct: 619 GS-EKMLKLWNV 629
>GBB_CRYPA (O14435) Guanine nucleotide-binding protein beta subunit| Length = 359 Score = 44.7 bits (104), Expect = 1e-04 Identities = 35/138 (25%), Positives = 60/138 (43%), Gaps = 1/138 (0%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 ++W+ ++ V GH + F P V+ S D T R++DI A R+ V ++ Sbjct: 227 KLWDIRAGKAVQTFAGHESDINAIQFFPDGHSFVTGSDDATCRLFDIRADRELNVYGSES 286 Query: 181 IM-RLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDT 357 I+ +T + T + G L+ +G DD + K+W + T Sbjct: 287 ILCGITSVATSVSG--------------------------RLLFAGYDDFECKVWDV--T 318 Query: 358 KAWEVDTLRGHMNNVSCV 411 + +V +L GH N VSC+ Sbjct: 319 RGEKVGSLVGHENRVSCL 336 Score = 37.0 bits (84), Expect = 0.027 Identities = 37/140 (26%), Positives = 57/140 (40%), Gaps = 1/140 (0%) Frame = +1 Query: 40 LTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDIMRLTQMNTDLFG 219 L+GH Y+ C F ++ S+ D T WDI K+ + AD + G Sbjct: 156 LSGHAGYLSCCRFINDRSILTSSG-DMTCMKWDIETGTKQ-IEFADHL-----------G 202 Query: 220 GVDAVVKYVLEGHDRGVNWASFHPTLP-LIVSGADDRQVKLWRMNDTKAWEVDTLRGHMN 396 V ++ S +PT +SGA D KLW + KA V T GH + Sbjct: 203 DVMSI---------------SLNPTNQNTFISGACDAFAKLWDIRAGKA--VQTFAGHES 245 Query: 397 NVSCVMFHAKQDIIVSNSED 456 +++ + F V+ S+D Sbjct: 246 DINAIQFFPDGHSFVTGSDD 265
>STRN3_HUMAN (Q13033) Striatin-3 (Cell-cycle autoantigen SG2NA) (S/G2 antigen)| Length = 797 Score = 44.7 bits (104), Expect = 1e-04 Identities = 36/135 (26%), Positives = 60/135 (44%), Gaps = 9/135 (6%) Frame = +1 Query: 100 VSASLDQTVRVWDIGALRKKTVSPADDIMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWA 279 + S D + V +G L TV+ D N D F + KY L H GV Sbjct: 428 IMGSDDVLLSVLGLGDLADLTVTNDADYSYDLPANKDAFRKTWSP-KYTLRSHFDGVRAL 486 Query: 280 SFHPTLPLIVSGADDRQVKLWRMNDT----KAWEVD-----TLRGHMNNVSCVMFHAKQD 432 +FHP P++V+ ++D +KLW + T K+ +D T R H+ V Sbjct: 487 AFHPVEPVLVTASEDHTLKLWNLQKTVPAKKSASLDVEPIYTFRAHIGPV--------LS 538 Query: 433 IIVSNSEDKAFASGM 477 + +S++ ++ F+ G+ Sbjct: 539 LAISSNGEQCFSGGI 553 Score = 33.5 bits (75), Expect = 0.30 Identities = 39/157 (24%), Positives = 59/157 (37%), Gaps = 9/157 (5%) Frame = +1 Query: 40 LTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDIMRLTQMNTDLFG 219 L H V +FHP E ++V+AS D T+++W++ +KTV PA L Sbjct: 476 LRSHFDGVRALAFHPVEPVLVTASEDHTLKLWNL----QKTV-PAKKSASL--------- 521 Query: 220 GVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVD-------- 375 D Y H V + SG D ++ W M D Sbjct: 522 --DVEPIYTFRAHIGPVLSLAISSNGEQCFSGGIDATIQWWNMPSPSVDPYDTYEPNVLA 579 Query: 376 -TLRGHMNNVSCVMFHAKQDIIVSNSEDKAFASGMPQ 483 TL GH + V + + ++ ++S S D PQ Sbjct: 580 GTLVGHTDAVWGLAYSGIKNQLLSCSADGTVRLWNPQ 616 Score = 33.1 bits (74), Expect = 0.40 Identities = 15/49 (30%), Positives = 25/49 (51%), Gaps = 4/49 (8%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGH----NHYVMCASFHPKEDLVVSASLDQTVRVW 135 R+WN S+TCV +T H + + +FH + + SA D +V+ Sbjct: 748 RLWNLDSKTCVQEITAHRKKLDESIYDVAFHSSKAYIASAGADALAKVF 796 Score = 32.0 bits (71), Expect = 0.88 Identities = 34/174 (19%), Positives = 66/174 (37%), Gaps = 26/174 (14%) Frame = +1 Query: 13 WQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWD----------IGALRKKT 162 ++ L GH V ++ ++ ++S S D TVR+W+ +K Sbjct: 573 YEPNVLAGTLVGHTDAVWGLAYSGIKNQLLSCSADGTVRLWNPQEKLPCICTYNGDKKHG 632 Query: 163 VSPADDIMRLTQMNTDLFGGVDAVVKYVLEGH----------DRG------VNWASFHPT 294 + + D + + + V Y LE D G +N HPT Sbjct: 633 IPTSVDFIGCDPAHMVTSFNTGSAVIYDLETSQSLVILSSQVDSGLQSNNHINRVVSHPT 692 Query: 295 LPLIVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 LP+ ++ +DR +K + K + ++ H++ V+ + ++S S D Sbjct: 693 LPVTITAHEDRHIKFFDNKTGKM--IHSMVAHLDAVTSLAVDPNGIYLMSGSHD 744
>CORO_DICDI (P27133) Coronin (p55)| Length = 445 Score = 44.7 bits (104), Expect = 1e-04 Identities = 42/151 (27%), Positives = 60/151 (39%), Gaps = 5/151 (3%) Frame = +1 Query: 25 TCVAVLTGHNHYVMCASFHP-KEDLVVSASLDQTVRVWDI--GALRKKTVSPADDIMRLT 195 T V + GH V+ +FHP E+LV S S D + +W I G L +P Sbjct: 70 TSVPLFNGHKSAVLDIAFHPFNENLVGSVSEDCNICIWGIPEGGLTDSISTPLQ------ 123 Query: 196 QMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLP-LIVSGADDRQVKLWRMNDTKAWEV 372 L GH R V SF P + V+ + D VK W + K + Sbjct: 124 ----------------TLSGHKRKVGTISFGPVADNVAVTSSGDFLVKTWDVEQGK--NL 165 Query: 373 DTLRGHMNNV-SCVMFHAKQDIIVSNSEDKA 462 T+ GH + + SC H I+ + + KA Sbjct: 166 TTVEGHSDMITSCEWNHNGSQIVTTCKDKKA 196
>WDR16_MOUSE (Q5F201) WD-repeat protein 16| Length = 620 Score = 44.7 bits (104), Expect = 1e-04 Identities = 43/171 (25%), Positives = 65/171 (38%), Gaps = 17/171 (9%) Frame = +1 Query: 1 RIWN--WQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPA 174 R+W Q++ L H V C + V+AS D T +WD+ LR+ + A Sbjct: 442 RVWQVGCQTQKLEEALKEHKSSVSCIRVKKNNEECVTASTDGTCIIWDLVRLRRNQMILA 501 Query: 175 DDIMRLTQMNTDLF----GGVDAVVKY----------VLEGHDRG-VNWASFHPTLPLIV 309 + + + + + F G D + Y LEG G +N V Sbjct: 502 NTLFQCVCYHPEEFQIITSGTDRKIAYWEVFDGSVIRELEGSLSGSINGMDITQEGGHFV 561 Query: 310 SGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSEDKA 462 +G D VK+W N+ + V GH N+ + IVS S D A Sbjct: 562 TGGHDHLVKVWDYNEGEVTHVGV--GHSGNIMAMRISPGNQYIVSVSADGA 610 Score = 29.6 bits (65), Expect = 4.4 Identities = 13/51 (25%), Positives = 27/51 (52%) Frame = +1 Query: 304 IVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 I+SG + +V++W++ + L+ H ++VSC+ + V+ S D Sbjct: 432 IISGGGEGEVRVWQVGCQTQKLEEALKEHKSSVSCIRVKKNNEECVTASTD 482
>GBLP_ORENI (O42249) Guanine nucleotide-binding protein beta subunit 2-like 1| (Receptor of activated protein kinase C) (RACK) Length = 317 Score = 44.3 bits (103), Expect = 2e-04 Identities = 34/125 (27%), Positives = 56/125 (44%), Gaps = 18/125 (14%) Frame = +1 Query: 40 LTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI--GALRKKTVSPADDIMRL--TQMNT 207 L GH+H+V +S + D T+R+WD+ G ++ V D++ + + N Sbjct: 59 LKGHSHFVSDVVISSDGQFALSGAWDGTLRLWDLTTGLTTRRFVGHTKDVLSVAFSADNR 118 Query: 208 DLFGG----------VDAVVKYVL--EGHDRGVNWASFHP--TLPLIVSGADDRQVKLWR 345 + G V KY + EGH V+ F P + P+IVS D+ VK+W Sbjct: 119 QIVSGSRDKTIKLWNTLGVCKYTIQDEGHTEWVSCVRFSPNSSNPIIVSCGWDKMVKVWN 178 Query: 346 MNDTK 360 + + K Sbjct: 179 LANCK 183 Score = 40.4 bits (93), Expect = 0.002 Identities = 39/149 (26%), Positives = 62/149 (41%), Gaps = 1/149 (0%) Frame = +1 Query: 16 QSRTCVAVLTGHNHYVMCASFHPK-EDLVVSASLDQTVRVWDIGALRKKTVSPADDIMRL 192 + T L GH+ +V + PK D+++SAS D+++ +W +L Sbjct: 3 EQMTVRGTLKGHSGWVTQIATTPKYPDMILSASRDKSIIMW-----------------KL 45 Query: 193 TQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEV 372 T+ T+ + + L+GH V+ +SGA D ++LW + T Sbjct: 46 TRDETNY-----GIPQRSLKGHSHFVSDVVISSDGQFALSGAWDGTLRLWDL--TTGLTT 98 Query: 373 DTLRGHMNNVSCVMFHAKQDIIVSNSEDK 459 GH +V V F A IVS S DK Sbjct: 99 RRFVGHTKDVLSVAFSADNRQIVSGSRDK 127
>TBL1Y_HUMAN (Q9BQ87) F-box-like/WD-repeat protein TBL1Y (Transducin beta-like| 1Y protein) (Transducin-beta-like 1, Y-linked) Length = 522 Score = 44.3 bits (103), Expect = 2e-04 Identities = 39/149 (26%), Positives = 63/149 (42%), Gaps = 15/149 (10%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTV----- 165 RIW ++ + L H + ++ K + V+SA +D+T +WD K Sbjct: 260 RIWT-ENGNLASTLGQHKGPIFALKWNKKGNYVLSAGVDKTTIIWDAHTGEAKQQFPFHS 318 Query: 166 SPADDI-----MRLTQMNTDLFG-----GVDAVVKYVLEGHDRGVNWASFHPTLPLIVSG 315 +PA D+ M +TD+ G D VK +GH VN + P+ L+ S Sbjct: 319 APALDVDWQNNMTFASCSTDMCIHVCRLGCDHPVK-TFQGHTNEVNAIKWDPSGMLLASC 377 Query: 316 ADDRQVKLWRMNDTKAWEVDTLRGHMNNV 402 +DD +K+W M V L+ H + Sbjct: 378 SDDMTLKIWSMKQDAC--VHDLQAHSKEI 404 Score = 38.9 bits (89), Expect = 0.007 Identities = 33/147 (22%), Positives = 58/147 (39%), Gaps = 6/147 (4%) Frame = +1 Query: 37 VLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDIMRLTQMNTDLF 216 VL GH V +++P DL+ S S D T R+W++ Sbjct: 174 VLRGHESEVFICAWNPVSDLLASGSGDSTARIWNLN-------------------ENSNG 214 Query: 217 GGVDAVVKYVLE--GHD----RGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVDT 378 G V+++ + GHD + V ++ L+ G+ D ++W N A T Sbjct: 215 GSTQLVLRHCIREGGHDVPSNKDVTSLDWNSDGTLLAMGSYDGFARIWTENGNLA---ST 271 Query: 379 LRGHMNNVSCVMFHAKQDIIVSNSEDK 459 L H + + ++ K + ++S DK Sbjct: 272 LGQHKGPIFALKWNKKGNYVLSAGVDK 298 Score = 35.8 bits (81), Expect = 0.061 Identities = 27/123 (21%), Positives = 43/123 (34%), Gaps = 9/123 (7%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHP---------KEDLVVSASLDQTVRVWDIGALR 153 +IW+ + CV L H+ + + P ++ SAS D TVR+WD+ Sbjct: 384 KIWSMKQDACVHDLQAHSKEIYTIKWSPTGPATSNPNSSIMLASASFDSTVRLWDVE--- 440 Query: 154 KKTVSPADDIMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQV 333 V + L H V +F P + SG+ D+ V Sbjct: 441 ------------------------QGVCTHTLMKHQEPVYSVAFSPDGKYLASGSFDKYV 476 Query: 334 KLW 342 +W Sbjct: 477 HIW 479 Score = 32.3 bits (72), Expect = 0.67 Identities = 13/46 (28%), Positives = 21/46 (45%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWD 138 R+W+ + C L H V +F P + S S D+ V +W+ Sbjct: 435 RLWDVEQGVCTHTLMKHQEPVYSVAFSPDGKYLASGSFDKYVHIWN 480
>GBB3_RAT (P52287) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 3 (Transducin beta chain 3) Length = 340 Score = 44.3 bits (103), Expect = 2e-04 Identities = 33/139 (23%), Positives = 54/139 (38%) Frame = +1 Query: 40 LTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDIMRLTQMNTDLFG 219 L+ H Y+ C F ++V S+ D T +WDI ++KT Sbjct: 139 LSAHTGYLSCCRFLDDNNIVTSSG-DTTCALWDIETGQQKT------------------- 178 Query: 220 GVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVDTLRGHMNN 399 V GH + P L +SGA D KLW + + + T GH ++ Sbjct: 179 --------VFVGHTGDCMSLAVSPDYKLFISGACDASAKLWDVREGTCRQ--TFTGHESD 228 Query: 400 VSCVMFHAKQDIIVSNSED 456 ++ + F + I + S+D Sbjct: 229 INAICFFPNGEAICTGSDD 247 Score = 43.9 bits (102), Expect = 2e-04 Identities = 34/152 (22%), Positives = 60/152 (39%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 ++W+ + TC TGH + F P + + + S D + R++D+ A ++ T + Sbjct: 209 KLWDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQELTAYSHES 268 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTK 360 I+ G+ +F + L+ +G DD +W + K Sbjct: 269 II-------------------------CGITSVAFSLSGRLLFAGYDDFNCNVW--DSLK 301 Query: 361 AWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 V L GH N VSC+ A + + S D Sbjct: 302 CERVGVLSGHDNRVSCLGVTADGMAVATGSWD 333 Score = 29.3 bits (64), Expect = 5.7 Identities = 14/44 (31%), Positives = 22/44 (50%), Gaps = 2/44 (4%) Frame = +1 Query: 13 WQSRTC--VAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWD 138 W S C V VL+GH++ V C V + S D +++W+ Sbjct: 297 WDSLKCERVGVLSGHDNRVSCLGVTADGMAVATGSWDSFLKIWN 340
>GBB3_MOUSE (Q61011) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 3 (Transducin beta chain 3) Length = 340 Score = 44.3 bits (103), Expect = 2e-04 Identities = 33/139 (23%), Positives = 54/139 (38%) Frame = +1 Query: 40 LTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDIMRLTQMNTDLFG 219 L+ H Y+ C F ++V S+ D T +WDI ++KT Sbjct: 139 LSAHTGYLSCCRFLDDNNIVTSSG-DTTCALWDIETGQQKT------------------- 178 Query: 220 GVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVDTLRGHMNN 399 V GH + P L +SGA D KLW + + + T GH ++ Sbjct: 179 --------VFVGHTGDCMSLAVSPDYKLFISGACDASAKLWDVREGTCRQ--TFTGHESD 228 Query: 400 VSCVMFHAKQDIIVSNSED 456 ++ + F + I + S+D Sbjct: 229 INAICFFPNGEAICTGSDD 247 Score = 43.9 bits (102), Expect = 2e-04 Identities = 34/152 (22%), Positives = 60/152 (39%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 ++W+ + TC TGH + F P + + + S D + R++D+ A ++ T + Sbjct: 209 KLWDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQELTAYSQES 268 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTK 360 I+ G+ +F + L+ +G DD +W + K Sbjct: 269 II-------------------------CGITSVAFSLSGRLLFAGYDDFNCNVW--DSLK 301 Query: 361 AWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 V L GH N VSC+ A + + S D Sbjct: 302 CERVGILSGHDNRVSCLGVTADGMAVATGSWD 333 Score = 28.9 bits (63), Expect = 7.5 Identities = 13/44 (29%), Positives = 22/44 (50%), Gaps = 2/44 (4%) Frame = +1 Query: 13 WQSRTC--VAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWD 138 W S C V +L+GH++ V C V + S D +++W+ Sbjct: 297 WDSLKCERVGILSGHDNRVSCLGVTADGMAVATGSWDSFLKIWN 340
>GBB3_HUMAN (P16520) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 3 (Transducin beta chain 3) Length = 340 Score = 44.3 bits (103), Expect = 2e-04 Identities = 33/139 (23%), Positives = 54/139 (38%) Frame = +1 Query: 40 LTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDIMRLTQMNTDLFG 219 L+ H Y+ C F ++V S+ D T +WDI ++KT Sbjct: 139 LSAHTGYLSCCRFLDDNNIVTSSG-DTTCALWDIETGQQKT------------------- 178 Query: 220 GVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVDTLRGHMNN 399 V GH + P L +SGA D KLW + + + T GH ++ Sbjct: 179 --------VFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQ--TFTGHESD 228 Query: 400 VSCVMFHAKQDIIVSNSED 456 ++ + F + I + S+D Sbjct: 229 INAICFFPNGEAICTGSDD 247 Score = 41.2 bits (95), Expect = 0.001 Identities = 33/152 (21%), Positives = 61/152 (40%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 ++W+ + TC TGH + F P + + + S D + R++D+ A ++ Sbjct: 209 KLWDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQE-------- 260 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTK 360 ++ + E G+ +F + L+ +G DD +W + K Sbjct: 261 -----------------LICFSHESIICGITSVAFSLSGRLLFAGYDDFNCNVW--DSMK 301 Query: 361 AWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 + V L GH N VSC+ A + + S D Sbjct: 302 SERVGILSGHDNRVSCLGVTADGMAVATGSWD 333 Score = 28.5 bits (62), Expect = 9.7 Identities = 11/45 (24%), Positives = 22/45 (48%) Frame = +1 Query: 4 IWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWD 138 +W+ V +L+GH++ V C V + S D +++W+ Sbjct: 296 VWDSMKSERVGILSGHDNRVSCLGVTADGMAVATGSWDSFLKIWN 340
>GBB2_CAEEL (Q20636) Guanine nucleotide-binding protein beta subunit 2| Length = 356 Score = 43.9 bits (102), Expect = 2e-04 Identities = 36/151 (23%), Positives = 57/151 (37%) Frame = +1 Query: 4 IWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDI 183 +W+ +S CV GH + FHP D + S D T R++D+ A R+ V + I Sbjct: 226 VWDIRSGQCVQSFEGHEADINTVRFHPNGDAFATGSDDATCRLFDLRADRQVCVYEKESI 285 Query: 184 MRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKA 363 + VN F + ++ +G D +V +W + K Sbjct: 286 L-------------------------FPVNGVDFSLSGRILFAGYGDYRVGVW--DSLKC 318 Query: 364 WEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 L GH N +SC+ + S S D Sbjct: 319 ARHSVLYGHENRISCLRTSPDGTAVCSASWD 349 Score = 36.2 bits (82), Expect = 0.047 Identities = 18/47 (38%), Positives = 24/47 (51%), Gaps = 2/47 (4%) Frame = +1 Query: 1 RIWNWQSRTCV--AVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVW 135 R+ W S C +VL GH + + C P V SAS D T+R+W Sbjct: 309 RVGVWDSLKCARHSVLYGHENRISCLRTSPDGTAVCSASWDCTIRIW 355
>GBLP_BIOGL (Q93134) Guanine nucleotide-binding protein beta subunit 2-like 1| (Receptor of activated protein kinase C) (RACK) Length = 316 Score = 43.9 bits (102), Expect = 2e-04 Identities = 41/158 (25%), Positives = 63/158 (39%), Gaps = 19/158 (12%) Frame = +1 Query: 40 LTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI--GALRKKTVSPADDIMRL--TQMNT 207 L GH H+V +S S D T+R+WD+ G ++ V D++ + + N Sbjct: 59 LHGHGHFVSDVILSSDGQFALSGSWDHTLRLWDLSTGQTTRRFVGHTKDVLSVAFSADNR 118 Query: 208 DLFGG----------VDAVVKYVLEGHDRGVNWAS---FHPTL--PLIVSGADDRQVKLW 342 + G V KY ++ D +W S F P P+IVS DR VK+W Sbjct: 119 QIVSGSRDKTIKLWNTLGVCKYTIQ-DDCHTDWTSCVRFSPNTQNPIIVSSGWDRLVKVW 177 Query: 343 RMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 + + K GH V+ V + S +D Sbjct: 178 NLTNCKL--KTNHYGHTGYVNTVTVSPDGSLCASGGKD 213 Score = 43.1 bits (100), Expect = 4e-04 Identities = 40/159 (25%), Positives = 63/159 (39%), Gaps = 20/159 (12%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 R+W+ + GH V+ +F +VS S D+T+++W+ + K T+ DD Sbjct: 88 RLWDLSTGQTTRRFVGHTKDVLSVAFSADNRQIVSGSRDKTIKLWNTLGVCKYTIQ--DD 145 Query: 181 ----------IMRLTQMNTDLFGGVDAVVKY----------VLEGHDRGVNWASFHPTLP 300 TQ + G D +VK GH VN + P Sbjct: 146 CHTDWTSCVRFSPNTQNPIIVSSGWDRLVKVWNLTNCKLKTNHYGHTGYVNTVTVSPDGS 205 Query: 301 LIVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMF 417 L SG D Q LW +N+ K + TL G + ++ + F Sbjct: 206 LCASGGKDSQAMLWDLNEGK--HLYTLDGAGDTINALCF 242 Score = 36.6 bits (83), Expect = 0.036 Identities = 38/149 (25%), Positives = 60/149 (40%), Gaps = 1/149 (0%) Frame = +1 Query: 16 QSRTCVAVLTGHNHYVMCASFHPK-EDLVVSASLDQTVRVWDIGALRKKTVSPADDIMRL 192 + T L GH +V + P+ D+++SAS D+++ VW RL Sbjct: 3 EQMTLRGTLQGHGGWVTQIATTPQYPDMILSASRDKSLIVW-----------------RL 45 Query: 193 TQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEV 372 T+ + V + L GH V+ +SG+ D ++LW ++ + Sbjct: 46 TRDESSY-----GVPQKSLHGHGHFVSDVILSSDGQFALSGSWDHTLRLWDLSTGQTTR- 99 Query: 373 DTLRGHMNNVSCVMFHAKQDIIVSNSEDK 459 GH +V V F A IVS S DK Sbjct: 100 -RFVGHTKDVLSVAFSADNRQIVSGSRDK 127
>UTP15_BRARE (Q7ZW33) U3 small nucleolar RNA-associated protein 15 homolog| Length = 517 Score = 43.9 bits (102), Expect = 2e-04 Identities = 42/164 (25%), Positives = 74/164 (45%), Gaps = 15/164 (9%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI-GALRKKTVSPAD 177 R+++ R + GH+ V SF V+S S D T RVWD+ A+ +++ Sbjct: 105 RLFDIGGRVSLRQFKGHSKAVHATSFLSDGFRVLSGSDDLTCRVWDVASAVELSSITEHT 164 Query: 178 DIMRL---TQMNTDLF--GGVDAVVKY--VLEG-------HDRGVNWASFHPTLPLIVSG 315 D +R +++N D+F G D VK V G H + V +P+ L+VS Sbjct: 165 DYIRAIAPSKLNPDVFVTGSYDHTVKMFDVRSGNSVMTMQHGQPVECVLLYPSEALLVS- 223 Query: 316 ADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSN 447 R VK+W + ++ +L+ H V+C + ++ ++ Sbjct: 224 TGGRYVKVWDLL-KGGQQLVSLKNHHKTVTCACLSSSNKLLTAS 266
>WSB1_FUGRU (Q9W5Z5) WD repeat and SOCS box-containing protein 1 (WSB-1)| Length = 427 Score = 43.9 bits (102), Expect = 2e-04 Identities = 39/151 (25%), Positives = 61/151 (40%) Frame = +1 Query: 4 IWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDI 183 +WN T + L GH++ V+ F P L+ +AS D V VWD + S ++ Sbjct: 245 LWNMDKYTLIRKLEGHHNDVVSCEFSPDGALLATASYDTRVIVWD-----HQRGSILLEL 299 Query: 184 MRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKA 363 L + +F G +DR V SF I S +DDR V+ W + + Sbjct: 300 GHLFPPPSPIFAG---------GANDRWVRSVSFCADGRHIASVSDDRLVRFWSIEERAP 350 Query: 364 WEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 V +L N C F ++ + + D Sbjct: 351 QAVASL----PNGLCCAFSTTGSVLAAGTCD 377 Score = 42.4 bits (98), Expect = 7e-04 Identities = 40/153 (26%), Positives = 61/153 (39%), Gaps = 1/153 (0%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLV-VSASLDQTVRVWDIGALRKKTVSPAD 177 +IW+ + T + L H V +F P L+ VSAS D+ +RVWD+ Sbjct: 158 KIWDVYTGTLLLNLMDHTDIVRDLTFAPDGSLMLVSASTDKKLRVWDLKD---------- 207 Query: 178 DIMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDT 357 D + VL GH V ++F P ++ S + V LW M+ Sbjct: 208 ----------------DGNMVKVLWGHPNRVYSSAFSPDSSVLCSVGASKAVLLWNMD-- 249 Query: 358 KAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 K + L GH N+V F ++ + S D Sbjct: 250 KYTLIRKLEGHHNDVVSCEFSPDGALLATASYD 282 Score = 34.3 bits (77), Expect = 0.18 Identities = 31/123 (25%), Positives = 55/123 (44%), Gaps = 11/123 (8%) Frame = +1 Query: 1 RIWNWQSR-TCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIG--ALRKKTVSP 171 R+W+ + V VL GH + V ++F P ++ S + V +W++ L +K Sbjct: 201 RVWDLKDDGNMVKVLWGHPNRVYSSAFSPDSSVLCSVGASKAVLLWNMDKYTLIRKLEGH 260 Query: 172 ADDIMRLTQMNTDLFGGVDAVVKY----VLEGHDRGVNWAS----FHPTLPLIVSGADDR 327 +D++ + + D G + A Y ++ H RG F P P+ GA+DR Sbjct: 261 HNDVVS-CEFSPD--GALLATASYDTRVIVWDHQRGSILLELGHLFPPPSPIFAGGANDR 317 Query: 328 QVK 336 V+ Sbjct: 318 WVR 320
>STRN3_MOUSE (Q9ERG2) Striatin-3 (Cell-cycle autoantigen SG2NA) (S/G2 antigen)| Length = 796 Score = 43.5 bits (101), Expect = 3e-04 Identities = 36/135 (26%), Positives = 59/135 (43%), Gaps = 9/135 (6%) Frame = +1 Query: 100 VSASLDQTVRVWDIGALRKKTVSPADDIMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWA 279 + S D + V +G L TV+ D N D F KY L H GV Sbjct: 427 IMGSDDVLLSVLGLGDLADLTVTNDADYSYDLPANKDAFRKTWNP-KYTLRSHFDGVRAL 485 Query: 280 SFHPTLPLIVSGADDRQVKLWRMNDT----KAWEVD-----TLRGHMNNVSCVMFHAKQD 432 +FHP P++V+ ++D +KLW + T K+ +D T R H+ V Sbjct: 486 AFHPVEPVLVTASEDHTLKLWNLQKTVPAKKSASLDVEPIYTFRAHIGPV--------LS 537 Query: 433 IIVSNSEDKAFASGM 477 + +S++ ++ F+ G+ Sbjct: 538 LAISSNGEQCFSGGI 552 Score = 36.2 bits (82), Expect = 0.047 Identities = 16/49 (32%), Positives = 26/49 (53%), Gaps = 4/49 (8%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGH----NHYVMCASFHPKEDLVVSASLDQTVRVW 135 R+WN S+TCV +T H + + +FHP + + SA D +V+ Sbjct: 747 RLWNLDSKTCVQEITAHRKKLDESIYDVAFHPSKAYIASAGADALAKVF 795 Score = 32.3 bits (72), Expect = 0.67 Identities = 30/118 (25%), Positives = 45/118 (38%) Frame = +1 Query: 40 LTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDIMRLTQMNTDLFG 219 L H V +FHP E ++V+AS D T+++W++ +KTV PA L Sbjct: 475 LRSHFDGVRALAFHPVEPVLVTASEDHTLKLWNL----QKTV-PAKKSASL--------- 520 Query: 220 GVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVDTLRGHM 393 D Y H V + SG D ++ W M DT ++ Sbjct: 521 --DVEPIYTFRAHIGPVLSLAISSNGEQCFSGGIDATIQWWNMPSPNVDPYDTYESNV 576 Score = 30.0 bits (66), Expect = 3.3 Identities = 34/174 (19%), Positives = 64/174 (36%), Gaps = 26/174 (14%) Frame = +1 Query: 13 WQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDIMRL 192 ++S L H V ++ ++ ++S S D T+R+W+ + D Sbjct: 572 YESNVLAGTLVAHTDAVWGLAYSGIKNQLLSCSADGTIRLWNPQEKLPCVCTYNGDKEHG 631 Query: 193 TQMNTDLFG----------GVDAVVKYVLEGH----------DRG------VNWASFHPT 294 + D G + V Y LE D G +N HPT Sbjct: 632 IPTSVDFIGCDPAHMVTSFNTGSAVIYDLETSQSLVMLSSQVDSGLQSSNHINRVVSHPT 691 Query: 295 LPLIVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 LP+ ++ +DR +K + K + ++ H++ V+ + ++S S D Sbjct: 692 LPVTITAHEDRHIKFFDNKTGKM--IHSMVAHLDAVTSLAVDPNGIYLMSGSHD 743
>LUB1_SCHPO (O94289) Ubiquitin homeostasis protein lub1| Length = 713 Score = 43.5 bits (101), Expect = 3e-04 Identities = 36/142 (25%), Positives = 58/142 (40%), Gaps = 19/142 (13%) Frame = +1 Query: 13 WQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDIMRL 192 W C VL GH V A ED+ ++ S D+ +++W+ L K ++ D + L Sbjct: 124 WALGQCKYVLKGHQSSVW-AVLALGEDIFITGSADKLIKIWNGEKLVKSILAHNDCVRSL 182 Query: 193 TQMNTDLFG-GVDAVVK---------YVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLW 342 Q+ D V+K Y L GH V ++ LI S +DR +++W Sbjct: 183 CQIPGGFASCSNDGVIKLWTSDGEFLYELHGHTSFVYSLTYIHNQQLIASCGEDRTIRIW 242 Query: 343 R---------MNDTKAWEVDTL 381 + + T W V +L Sbjct: 243 KGKECLQCITLPTTSVWSVSSL 264 Score = 37.0 bits (84), Expect = 0.027 Identities = 32/149 (21%), Positives = 63/149 (42%), Gaps = 9/149 (6%) Frame = +1 Query: 40 LTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDIMRLTQMNTDLF- 216 L GH + C++ + +++ S D T RVW +G + + + + D+F Sbjct: 94 LFGHESNI-CSASALNSETIITGSWDSTARVWALGQCKYVLKGHQSSVWAVLALGEDIFI 152 Query: 217 -GGVDAVVKYVLEGHDRGVNWASFHPTLPLI-------VSGADDRQVKLWRMNDTKAWEV 372 G D ++K + G + + + + + S ++D +KLW + +E Sbjct: 153 TGSADKLIK-IWNGEKLVKSILAHNDCVRSLCQIPGGFASCSNDGVIKLWTSDGEFLYE- 210 Query: 373 DTLRGHMNNVSCVMFHAKQDIIVSNSEDK 459 L GH + V + + Q +I S ED+ Sbjct: 211 --LHGHTSFVYSLTYIHNQQLIASCGEDR 237
>HAT2_NEUCR (Q7S7N3) Histone acetyltransferase type B subunit 2 (EC 2.3.1.48)| Length = 564 Score = 43.5 bits (101), Expect = 3e-04 Identities = 26/109 (23%), Positives = 48/109 (44%), Gaps = 2/109 (1%) Frame = +1 Query: 22 RTCVAVLTGHNHYVMCASFHPK-EDLVVSASLDQTVRVWDIGALRKKTVSPADDIMRLTQ 198 + + GH+ + +F+P+ E ++ +AS D+T+ +WD+ ++ K Sbjct: 278 KAAIVARNGHSDAINALAFNPRVETIIATASADKTIGIWDMRNMKSKV------------ 325 Query: 199 MNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIV-SGADDRQVKLW 342 + LEGH V +HPT I+ SG+ DR++ W Sbjct: 326 --------------HTLEGHQDAVTSLEWHPTESAILGSGSYDRRLLFW 360
>GBB1_HOMAM (O45040) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 1 (Transducin beta chain 1) Length = 340 Score = 43.5 bits (101), Expect = 3e-04 Identities = 39/153 (25%), Positives = 61/153 (39%), Gaps = 17/153 (11%) Frame = +1 Query: 4 IWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI--GALRKKTVSPAD 177 +W+ ++ TGH VM S P S + D + ++WDI G R+ Sbjct: 168 LWDIETGQQCTQFTGHTGDVMSLSLSPNMRTFTSGACDASAKLWDIRDGMCRQTFPGHES 227 Query: 178 DIMRLTQM-NTDLF--GGVDAVVK---------YVLEGHDR---GVNWASFHPTLPLIVS 312 DI +T N F G DA + + HD G+ +F + L+++ Sbjct: 228 DINAVTFFPNGHAFATGSDDATCRLFDIRADQELAMYSHDNIICGITSVAFSKSGKLLLA 287 Query: 313 GADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCV 411 G DD +W + + L GH N VSC+ Sbjct: 288 GYDDFNCNVW--DSMRTERAGVLAGHDNRVSCL 318
>YDEM_CAEEL (Q19124) Hypothetical WD-repeat protein F02E8.5| Length = 578 Score = 43.1 bits (100), Expect = 4e-04 Identities = 20/63 (31%), Positives = 35/63 (55%), Gaps = 1/63 (1%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALR-KKTVSPAD 177 RIWN + ++ L+GH+ V C F+ VS S D+ +++WDI R +++ PA Sbjct: 361 RIWNLDNSRLLSTLSGHSDQVTCVKFYQSHS-AVSGSADRVIKIWDIQNQRCSRSLFPAS 419 Query: 178 DIM 186 ++ Sbjct: 420 KVL 422 Score = 35.0 bits (79), Expect = 0.10 Identities = 15/51 (29%), Positives = 32/51 (62%) Frame = +1 Query: 307 VSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSEDK 459 ++ ++D+ V++W +++++ + TL GH + V+CV F+ VS S D+ Sbjct: 352 IASSNDKNVRIWNLDNSRL--LSTLSGHSDQVTCVKFYQSHS-AVSGSADR 399
>GBLP_RAT (P63245) Guanine nucleotide-binding protein beta subunit 2-like 1| (Receptor of activated protein kinase C 1) (RACK1) (Receptor for activated C kinase) Length = 316 Score = 43.1 bits (100), Expect = 4e-04 Identities = 34/125 (27%), Positives = 55/125 (44%), Gaps = 18/125 (14%) Frame = +1 Query: 40 LTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI--GALRKKTVSPADDIMRL--TQMNT 207 L GH+H+V +S S D T+R+WD+ G ++ V D++ + + N Sbjct: 58 LRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNR 117 Query: 208 DLFGG----------VDAVVKYVL--EGHDRGVNWASFHP--TLPLIVSGADDRQVKLWR 345 + G V KY + E H V+ F P + P+IVS D+ VK+W Sbjct: 118 QIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWN 177 Query: 346 MNDTK 360 + + K Sbjct: 178 LANCK 182 Score = 42.0 bits (97), Expect = 9e-04 Identities = 44/171 (25%), Positives = 68/171 (39%), Gaps = 23/171 (13%) Frame = +1 Query: 16 QSRTCVAVLTGHNHYVMCASFHPK-EDLVVSASLDQTVRVWDIGALRKKTVSP------- 171 + T L GHN +V + P+ D+++SAS D+T+ +W + P Sbjct: 2 EQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGH 61 Query: 172 ---ADDIMRLTQMNTDLFGGVDAVVKY----------VLEGHDRGVNWASFHPTLPLIVS 312 D++ + L G D ++ GH + V +F IVS Sbjct: 62 SHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVS 121 Query: 313 GADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMF--HAKQDIIVSNSEDK 459 G+ D+ +KLW + V H VSCV F ++ IIVS DK Sbjct: 122 GSRDKTIKLWNTLGVCKYTVQD-ESHSEWVSCVRFSPNSSNPIIVSCGWDK 171
>GBLP_PIG (P63246) Guanine nucleotide-binding protein beta subunit 2-like 1| (Receptor of activated protein kinase C 1) (RACK1) (Receptor for activated C kinase) Length = 316 Score = 43.1 bits (100), Expect = 4e-04 Identities = 34/125 (27%), Positives = 55/125 (44%), Gaps = 18/125 (14%) Frame = +1 Query: 40 LTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI--GALRKKTVSPADDIMRL--TQMNT 207 L GH+H+V +S S D T+R+WD+ G ++ V D++ + + N Sbjct: 58 LRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNR 117 Query: 208 DLFGG----------VDAVVKYVL--EGHDRGVNWASFHP--TLPLIVSGADDRQVKLWR 345 + G V KY + E H V+ F P + P+IVS D+ VK+W Sbjct: 118 QIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWN 177 Query: 346 MNDTK 360 + + K Sbjct: 178 LANCK 182 Score = 42.0 bits (97), Expect = 9e-04 Identities = 44/171 (25%), Positives = 68/171 (39%), Gaps = 23/171 (13%) Frame = +1 Query: 16 QSRTCVAVLTGHNHYVMCASFHPK-EDLVVSASLDQTVRVWDIGALRKKTVSP------- 171 + T L GHN +V + P+ D+++SAS D+T+ +W + P Sbjct: 2 EQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGH 61 Query: 172 ---ADDIMRLTQMNTDLFGGVDAVVKY----------VLEGHDRGVNWASFHPTLPLIVS 312 D++ + L G D ++ GH + V +F IVS Sbjct: 62 SHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVS 121 Query: 313 GADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMF--HAKQDIIVSNSEDK 459 G+ D+ +KLW + V H VSCV F ++ IIVS DK Sbjct: 122 GSRDKTIKLWNTLGVCKYTVQD-ESHSEWVSCVRFSPNSSNPIIVSCGWDK 171
>GBLP_MOUSE (P68040) Guanine nucleotide-binding protein beta subunit 2-like 1| (Receptor of activated protein kinase C 1) (RACK1) (Receptor for activated C kinase) (p205) (12-3) Length = 316 Score = 43.1 bits (100), Expect = 4e-04 Identities = 34/125 (27%), Positives = 55/125 (44%), Gaps = 18/125 (14%) Frame = +1 Query: 40 LTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI--GALRKKTVSPADDIMRL--TQMNT 207 L GH+H+V +S S D T+R+WD+ G ++ V D++ + + N Sbjct: 58 LRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNR 117 Query: 208 DLFGG----------VDAVVKYVL--EGHDRGVNWASFHP--TLPLIVSGADDRQVKLWR 345 + G V KY + E H V+ F P + P+IVS D+ VK+W Sbjct: 118 QIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWN 177 Query: 346 MNDTK 360 + + K Sbjct: 178 LANCK 182 Score = 42.0 bits (97), Expect = 9e-04 Identities = 44/171 (25%), Positives = 68/171 (39%), Gaps = 23/171 (13%) Frame = +1 Query: 16 QSRTCVAVLTGHNHYVMCASFHPK-EDLVVSASLDQTVRVWDIGALRKKTVSP------- 171 + T L GHN +V + P+ D+++SAS D+T+ +W + P Sbjct: 2 EQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGH 61 Query: 172 ---ADDIMRLTQMNTDLFGGVDAVVKY----------VLEGHDRGVNWASFHPTLPLIVS 312 D++ + L G D ++ GH + V +F IVS Sbjct: 62 SHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVS 121 Query: 313 GADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMF--HAKQDIIVSNSEDK 459 G+ D+ +KLW + V H VSCV F ++ IIVS DK Sbjct: 122 GSRDKTIKLWNTLGVCKYTVQD-ESHSEWVSCVRFSPNSSNPIIVSCGWDK 171
>GBLP_MACFA (Q4R7Y4) Guanine nucleotide-binding protein beta subunit 2-like 1| Length = 316 Score = 43.1 bits (100), Expect = 4e-04 Identities = 34/125 (27%), Positives = 55/125 (44%), Gaps = 18/125 (14%) Frame = +1 Query: 40 LTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI--GALRKKTVSPADDIMRL--TQMNT 207 L GH+H+V +S S D T+R+WD+ G ++ V D++ + + N Sbjct: 58 LRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNR 117 Query: 208 DLFGG----------VDAVVKYVL--EGHDRGVNWASFHP--TLPLIVSGADDRQVKLWR 345 + G V KY + E H V+ F P + P+IVS D+ VK+W Sbjct: 118 QIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWN 177 Query: 346 MNDTK 360 + + K Sbjct: 178 LANCK 182 Score = 42.0 bits (97), Expect = 9e-04 Identities = 44/171 (25%), Positives = 68/171 (39%), Gaps = 23/171 (13%) Frame = +1 Query: 16 QSRTCVAVLTGHNHYVMCASFHPK-EDLVVSASLDQTVRVWDIGALRKKTVSP------- 171 + T L GHN +V + P+ D+++SAS D+T+ +W + P Sbjct: 2 EQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGH 61 Query: 172 ---ADDIMRLTQMNTDLFGGVDAVVKY----------VLEGHDRGVNWASFHPTLPLIVS 312 D++ + L G D ++ GH + V +F IVS Sbjct: 62 SHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVS 121 Query: 313 GADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMF--HAKQDIIVSNSEDK 459 G+ D+ +KLW + V H VSCV F ++ IIVS DK Sbjct: 122 GSRDKTIKLWNTLGVCKYTVQD-ESHSEWVSCVRFSPNSSNPIIVSCGWDK 171
>GBLP_HUMAN (P63244) Guanine nucleotide-binding protein beta subunit 2-like 1| (Guanine nucleotide-binding protein beta subunit-like protein 12.3) (Receptor of activated protein kinase C 1) (RACK1) (Receptor for activated C kinase) Length = 316 Score = 43.1 bits (100), Expect = 4e-04 Identities = 34/125 (27%), Positives = 55/125 (44%), Gaps = 18/125 (14%) Frame = +1 Query: 40 LTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI--GALRKKTVSPADDIMRL--TQMNT 207 L GH+H+V +S S D T+R+WD+ G ++ V D++ + + N Sbjct: 58 LRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNR 117 Query: 208 DLFGG----------VDAVVKYVL--EGHDRGVNWASFHP--TLPLIVSGADDRQVKLWR 345 + G V KY + E H V+ F P + P+IVS D+ VK+W Sbjct: 118 QIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWN 177 Query: 346 MNDTK 360 + + K Sbjct: 178 LANCK 182 Score = 42.0 bits (97), Expect = 9e-04 Identities = 44/171 (25%), Positives = 68/171 (39%), Gaps = 23/171 (13%) Frame = +1 Query: 16 QSRTCVAVLTGHNHYVMCASFHPK-EDLVVSASLDQTVRVWDIGALRKKTVSP------- 171 + T L GHN +V + P+ D+++SAS D+T+ +W + P Sbjct: 2 EQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGH 61 Query: 172 ---ADDIMRLTQMNTDLFGGVDAVVKY----------VLEGHDRGVNWASFHPTLPLIVS 312 D++ + L G D ++ GH + V +F IVS Sbjct: 62 SHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVS 121 Query: 313 GADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMF--HAKQDIIVSNSEDK 459 G+ D+ +KLW + V H VSCV F ++ IIVS DK Sbjct: 122 GSRDKTIKLWNTLGVCKYTVQD-ESHSEWVSCVRFSPNSSNPIIVSCGWDK 171
>GBLP_BOVIN (P63243) Guanine nucleotide-binding protein beta subunit 2-like 1| (Receptor of activated protein kinase C 1) (RACK1) (Receptor for activated C kinase) Length = 316 Score = 43.1 bits (100), Expect = 4e-04 Identities = 34/125 (27%), Positives = 55/125 (44%), Gaps = 18/125 (14%) Frame = +1 Query: 40 LTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI--GALRKKTVSPADDIMRL--TQMNT 207 L GH+H+V +S S D T+R+WD+ G ++ V D++ + + N Sbjct: 58 LRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNR 117 Query: 208 DLFGG----------VDAVVKYVL--EGHDRGVNWASFHP--TLPLIVSGADDRQVKLWR 345 + G V KY + E H V+ F P + P+IVS D+ VK+W Sbjct: 118 QIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWN 177 Query: 346 MNDTK 360 + + K Sbjct: 178 LANCK 182 Score = 42.0 bits (97), Expect = 9e-04 Identities = 44/171 (25%), Positives = 68/171 (39%), Gaps = 23/171 (13%) Frame = +1 Query: 16 QSRTCVAVLTGHNHYVMCASFHPK-EDLVVSASLDQTVRVWDIGALRKKTVSP------- 171 + T L GHN +V + P+ D+++SAS D+T+ +W + P Sbjct: 2 EQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGH 61 Query: 172 ---ADDIMRLTQMNTDLFGGVDAVVKY----------VLEGHDRGVNWASFHPTLPLIVS 312 D++ + L G D ++ GH + V +F IVS Sbjct: 62 SHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVS 121 Query: 313 GADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMF--HAKQDIIVSNSEDK 459 G+ D+ +KLW + V H VSCV F ++ IIVS DK Sbjct: 122 GSRDKTIKLWNTLGVCKYTVQD-ESHSEWVSCVRFSPNSSNPIIVSCGWDK 171
>PRP4_MOUSE (Q9DAW6) U4/U6 small nuclear ribonucleoprotein Prp4 (U4/U6 snRNP 60| kDa protein) (WD splicing factor Prp4) Length = 521 Score = 43.1 bits (100), Expect = 4e-04 Identities = 36/163 (22%), Positives = 59/163 (36%), Gaps = 2/163 (1%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 R+W+ ++ C+ L GH + +F P + + S D T +VWD+ R Sbjct: 389 RVWDLRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRR--------- 439 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTL-PLIVSGADDRQVKLWRMNDT 357 Y + H V F P +++GA D K+W Sbjct: 440 ------------------CVYTIPAHQNLVTGVKFEPIHGDFLLTGAYDNTAKIW---TH 478 Query: 358 KAWE-VDTLRGHMNNVSCVMFHAKQDIIVSNSEDKAFASGMPQ 483 W + TL GH V + + +I + S D+ F M + Sbjct: 479 PGWSPLKTLAGHEGKVMGLDISSDGQLIATCSYDRTFKLWMAE 521 Score = 42.4 bits (98), Expect = 7e-04 Identities = 38/154 (24%), Positives = 63/154 (40%), Gaps = 15/154 (9%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPAD- 177 ++W+ S VA + GH V +HP + + D++ R+WD+ A + Sbjct: 305 KLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQEEILHQEGHS 364 Query: 178 ----DIMRLTQMNTDLFGGVDAVVK----------YVLEGHDRGVNWASFHPTLPLIVSG 315 DI + GG+DA + LEGH + + +F P I +G Sbjct: 365 MGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPNGYHIATG 424 Query: 316 ADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMF 417 + D K+W + + V T+ H N V+ V F Sbjct: 425 SGDNTCKVWDLRQRRC--VYTIPAHQNLVTGVKF 456 Score = 40.8 bits (94), Expect = 0.002 Identities = 19/67 (28%), Positives = 32/67 (47%) Frame = +1 Query: 253 GHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQD 432 G DR +++ F P ++ + KLW + D + TLRGH NV ++FH K Sbjct: 228 GDDRPISYCHFSPNSKMLATACWSGLCKLWSVPDCSL--LHTLRGHNTNVGAIVFHPKST 285 Query: 433 IIVSNSE 453 + + + Sbjct: 286 VSLDQKD 292 Score = 35.8 bits (81), Expect = 0.061 Identities = 36/140 (25%), Positives = 59/140 (42%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 ++W+ + + L GHN V FHPK + SLDQ D+ AD Sbjct: 255 KLWSVPDCSLLHTLRGHNTNVGAIVFHPKS----TVSLDQK----DVNL----ASCAADG 302 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTK 360 ++L +++D + V +EGH V +HP+ + + DR +LW + + Sbjct: 303 SVKLWSLDSD-----EPVAD--IEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQE 355 Query: 361 AWEVDTLRGHMNNVSCVMFH 420 E+ GH V + FH Sbjct: 356 --EILHQEGHSMGVYDIAFH 373 Score = 34.3 bits (77), Expect = 0.18 Identities = 25/88 (28%), Positives = 41/88 (46%), Gaps = 8/88 (9%) Frame = +1 Query: 226 DAVVKYVLEGHDRGVNWASFHP--TLPL------IVSGADDRQVKLWRMNDTKAWEVDTL 381 D + + L GH+ V FHP T+ L + S A D VKLW ++ + V + Sbjct: 261 DCSLLHTLRGHNTNVGAIVFHPKSTVSLDQKDVNLASCAADGSVKLWSLDSDE--PVADI 318 Query: 382 RGHMNNVSCVMFHAKQDIIVSNSEDKAF 465 GH V+ VM+H + + D+++ Sbjct: 319 EGHTVRVARVMWHPSGRFLGTTCYDRSW 346
>GBLP_CHICK (P63247) Guanine nucleotide-binding protein beta subunit 2-like 1| (Guanine nucleotide-binding protein beta subunit-like protein 12.3) (Receptor of activated protein kinase C 1) (RACK1) (Receptor for activated C kinase) Length = 317 Score = 43.1 bits (100), Expect = 4e-04 Identities = 34/125 (27%), Positives = 55/125 (44%), Gaps = 18/125 (14%) Frame = +1 Query: 40 LTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI--GALRKKTVSPADDIMRL--TQMNT 207 L GH+H+V +S S D T+R+WD+ G ++ V D++ + + N Sbjct: 59 LRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNR 118 Query: 208 DLFGG----------VDAVVKYVL--EGHDRGVNWASFHP--TLPLIVSGADDRQVKLWR 345 + G V KY + E H V+ F P + P+IVS D+ VK+W Sbjct: 119 QIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWN 178 Query: 346 MNDTK 360 + + K Sbjct: 179 LANCK 183 Score = 42.0 bits (97), Expect = 9e-04 Identities = 44/171 (25%), Positives = 68/171 (39%), Gaps = 23/171 (13%) Frame = +1 Query: 16 QSRTCVAVLTGHNHYVMCASFHPK-EDLVVSASLDQTVRVWDIGALRKKTVSP------- 171 + T L GHN +V + P+ D+++SAS D+T+ +W + P Sbjct: 3 EQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGH 62 Query: 172 ---ADDIMRLTQMNTDLFGGVDAVVKY----------VLEGHDRGVNWASFHPTLPLIVS 312 D++ + L G D ++ GH + V +F IVS Sbjct: 63 SHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVS 122 Query: 313 GADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMF--HAKQDIIVSNSEDK 459 G+ D+ +KLW + V H VSCV F ++ IIVS DK Sbjct: 123 GSRDKTIKLWNTLGVCKYTVQD-ESHSEWVSCVRFSPNSSNPIIVSCGWDK 172
>STRN_MOUSE (O55106) Striatin| Length = 780 Score = 43.1 bits (100), Expect = 4e-04 Identities = 22/82 (26%), Positives = 39/82 (47%), Gaps = 9/82 (10%) Frame = +1 Query: 238 KYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDT----KAWEVD-----TLRGH 390 K+ L H G+ +FHP P++++ ++D +K+W + T K+ +D T R H Sbjct: 456 KFTLRSHFDGIRALAFHPIEPVLITASEDHTLKMWNLQKTAPAKKSTSLDVEPIYTFRAH 515 Query: 391 MNNVSCVMFHAKQDIIVSNSED 456 V CV+ + + S D Sbjct: 516 KGPVLCVVMSSNGEQCYSGGTD 537 Score = 34.7 bits (78), Expect = 0.14 Identities = 15/49 (30%), Positives = 25/49 (51%), Gaps = 4/49 (8%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGH----NHYVMCASFHPKEDLVVSASLDQTVRVW 135 R+WN +S+TC+ T H + +FHP + + SA D +V+ Sbjct: 731 RLWNLESKTCIQEFTAHRKKFEESIHDVAFHPSKCYIASAGADALAKVF 779 Score = 31.6 bits (70), Expect = 1.2 Identities = 33/148 (22%), Positives = 60/148 (40%), Gaps = 9/148 (6%) Frame = +1 Query: 40 LTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDIMRLTQMNTDLFG 219 L H + +FHP E ++++AS D T+++W++ + +PA + +T L Sbjct: 459 LRSHFDGIRALAFHPIEPVLITASEDHTLKMWNL-----QKTAPA-------KKSTSL-- 504 Query: 220 GVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLW-----RMNDTKAWEVDTLR 384 D Y H V SG D +++ W ++ A++ LR Sbjct: 505 --DVEPIYTFRAHKGPVLCVVMSSNGEQCYSGGTDGRIQSWSTTNPNVDPYDAYDPSVLR 562 Query: 385 ----GHMNNVSCVMFHAKQDIIVSNSED 456 GH + V + + A ++S S D Sbjct: 563 GPLLGHTDAVWGLAYSAAHQRLLSCSAD 590 Score = 31.2 bits (69), Expect = 1.5 Identities = 16/63 (25%), Positives = 31/63 (49%) Frame = +1 Query: 268 VNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSN 447 +N HPTLP+ ++ +DR +K + N K + ++ H+ V+ + ++S Sbjct: 667 INRVISHPTLPISITAHEDRHIKFYDNNTGKL--IHSMVAHLEAVTSLAVDPNGLYLMSG 724 Query: 448 SED 456 S D Sbjct: 725 SHD 727
>STRN_HUMAN (O43815) Striatin| Length = 780 Score = 43.1 bits (100), Expect = 4e-04 Identities = 22/82 (26%), Positives = 39/82 (47%), Gaps = 9/82 (10%) Frame = +1 Query: 238 KYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDT----KAWEVD-----TLRGH 390 K+ L H G+ +FHP P++++ ++D +K+W + T K+ +D T R H Sbjct: 456 KFTLRSHFDGIRALAFHPIEPVLITASEDHTLKMWNLQKTAPAKKSTSLDVEPIYTFRAH 515 Query: 391 MNNVSCVMFHAKQDIIVSNSED 456 V CV+ + + S D Sbjct: 516 KGPVLCVVMSSNGEQCYSGGTD 537 Score = 34.7 bits (78), Expect = 0.14 Identities = 15/49 (30%), Positives = 25/49 (51%), Gaps = 4/49 (8%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGH----NHYVMCASFHPKEDLVVSASLDQTVRVW 135 R+WN +S+TC+ T H + +FHP + + SA D +V+ Sbjct: 731 RLWNLESKTCIQEFTAHRKKFEESIHDVAFHPSKCYIASAGADALAKVF 779 Score = 30.8 bits (68), Expect = 2.0 Identities = 11/34 (32%), Positives = 22/34 (64%) Frame = +1 Query: 40 LTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI 141 L H + +FHP E ++++AS D T+++W++ Sbjct: 459 LRSHFDGIRALAFHPIEPVLITASEDHTLKMWNL 492
>PRP4_YEAST (P20053) U4/U6 small nuclear ribonucleoprotein PRP4| Length = 465 Score = 43.1 bits (100), Expect = 4e-04 Identities = 34/146 (23%), Positives = 63/146 (43%), Gaps = 15/146 (10%) Frame = +1 Query: 40 LTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD--IMRLT-QMNTD 210 L GH + +HP + SAS D T R+WD ++ + D + L+ Q + Sbjct: 261 LVGHERRISDVKYHPSGKFIGSASHDMTWRLWDASTHQELLLQEGHDKGVFSLSFQCDGS 320 Query: 211 LF--GGVDAVVK----------YVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMND 354 L GG+D++ L GH + + ++ P + +G D + +W + Sbjct: 321 LVCSGGMDSLSMLWDIRSGSKVMTLAGHSKPIYTVAWSPNGYQVATGGGDGIINVWDIRK 380 Query: 355 TKAWEVDTLRGHMNNVSCVMFHAKQD 432 +++ + H N V+ V F +K+D Sbjct: 381 RDEGQLNQILAHRNIVTQVRF-SKED 405 Score = 38.1 bits (87), Expect = 0.012 Identities = 34/135 (25%), Positives = 54/135 (40%), Gaps = 22/135 (16%) Frame = +1 Query: 4 IWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDI 183 +W+ +S + V L GH+ + ++ P V + D + VWDI RK+ + I Sbjct: 333 LWDIRSGSKVMTLAGHSKPIYTVAWSPNGYQVATGGGDGIINVWDI---RKRDEGQLNQI 389 Query: 184 MRLTQMNTDL-FGGVDAVVKYVLEGHDRGVNWASFHPTLPL------------------- 303 + + T + F D K V G+D +N S L + Sbjct: 390 LAHRNIVTQVRFSKEDGGKKLVSCGYDNLINVYSSDTWLKMGSLAGHTDKIISLDISNNS 449 Query: 304 --IVSGADDRQVKLW 342 +VSG DR +KLW Sbjct: 450 HFLVSGGWDRSIKLW 464
>PFS2_YEAST (P42841) Protein PFS2| Length = 465 Score = 43.1 bits (100), Expect = 4e-04 Identities = 31/145 (21%), Positives = 65/145 (44%), Gaps = 20/145 (13%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHP-KEDLVVSASLDQTVRVWDIGALRKKTVSPAD 177 ++W+ +S C++ + H V+ F P K +L+++ S D++ RV+DI K+ + D Sbjct: 244 KLWDPRSGNCISSILKFKHTVLKTRFQPTKGNLLMAISKDKSCRVFDIRYSMKELMCVRD 303 Query: 178 DIMRLTQ-------------------MNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLP 300 + +T + DL ++ + + HD+ + S++P Sbjct: 304 ETDYMTLEWHPINESMFTLACYDGSLKHFDLLQNLNEPILTIPYAHDKCITSLSYNPVGH 363 Query: 301 LIVSGADDRQVKLWRMNDTKAWEVD 375 + + A DR ++ W T+A +D Sbjct: 364 IFATAAKDRTIRFW----TRARPID 384 Score = 42.0 bits (97), Expect = 9e-04 Identities = 18/46 (39%), Positives = 28/46 (60%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWD 138 +IWN+ + VL+GH+ V +HP+ L+ SAS D V++WD Sbjct: 202 KIWNFSNGKQERVLSGHHWDVKSCDWHPEMGLIASASKDNLVKLWD 247 Score = 42.0 bits (97), Expect = 9e-04 Identities = 29/128 (22%), Positives = 50/128 (39%), Gaps = 15/128 (11%) Frame = +1 Query: 4 IWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPA--D 177 +WN S T ++ H+ V + D ++S D +++W K + A + Sbjct: 119 LWNASSFTFETLMQAHDSAVTTMKYSHDSDWMISGDADGMIKIWQPNFSMVKEIDAAHTE 178 Query: 178 DIMRLTQMNTD-------------LFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGA 318 I + + D ++ + + VL GH V +HP + LI S + Sbjct: 179 SIRDMAFSSNDSKFVTCSDDNILKIWNFSNGKQERVLSGHHWDVKSCDWHPEMGLIASAS 238 Query: 319 DDRQVKLW 342 D VKLW Sbjct: 239 KDNLVKLW 246 Score = 32.3 bits (72), Expect = 0.67 Identities = 16/71 (22%), Positives = 33/71 (46%) Frame = +1 Query: 244 VLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHA 423 +++ HD V + ++SG D +K+W+ N + E+D H ++ + F + Sbjct: 130 LMQAHDSAVTTMKYSHDSDWMISGDADGMIKIWQPNFSMVKEIDA--AHTESIRDMAFSS 187 Query: 424 KQDIIVSNSED 456 V+ S+D Sbjct: 188 NDSKFVTCSDD 198
>HIRA_DROME (O17468) HIRA protein homolog (dHIRA)| Length = 1047 Score = 43.1 bits (100), Expect = 4e-04 Identities = 30/121 (24%), Positives = 48/121 (39%) Frame = +1 Query: 10 NWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDIMR 189 N +S C L GH+ V+ ++ P + + S S+D TV +WD A + Sbjct: 115 NHESWKCFYTLRGHDGDVLDLAWSPNDVYLASCSIDNTVIIWDAQAFPHSVAT------- 167 Query: 190 LTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWE 369 L+GH V S+ P + S +DDR +K+W +T W Sbjct: 168 -------------------LKGHTGLVKGVSWDPLGRFLASQSDDRSIKIW---NTMNWS 205 Query: 370 V 372 + Sbjct: 206 L 206 Score = 32.0 bits (71), Expect = 0.88 Identities = 23/76 (30%), Positives = 36/76 (47%), Gaps = 2/76 (2%) Frame = +1 Query: 241 YVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAW--EVDTLRGHMNNVSCVM 414 Y L GHD V ++ P + S + D V +W D +A+ V TL+GH V V Sbjct: 123 YTLRGHDGDVLDLAWSPNDVYLASCSIDNTVIIW---DAQAFPHSVATLKGHTGLVKGVS 179 Query: 415 FHAKQDIIVSNSEDKA 462 + + S S+D++ Sbjct: 180 WDPLGRFLASQSDDRS 195
>STRN_RAT (P70483) Striatin| Length = 780 Score = 43.1 bits (100), Expect = 4e-04 Identities = 22/82 (26%), Positives = 39/82 (47%), Gaps = 9/82 (10%) Frame = +1 Query: 238 KYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDT----KAWEVD-----TLRGH 390 K+ L H G+ +FHP P++++ ++D +K+W + T K+ +D T R H Sbjct: 456 KFTLRSHFDGIRALAFHPIEPVLITASEDHTLKMWNLQKTAPAKKSTSLDVEPIYTFRAH 515 Query: 391 MNNVSCVMFHAKQDIIVSNSED 456 V CV+ + + S D Sbjct: 516 KGPVLCVVMSSNGEQCYSGGTD 537 Score = 34.7 bits (78), Expect = 0.14 Identities = 15/49 (30%), Positives = 25/49 (51%), Gaps = 4/49 (8%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGH----NHYVMCASFHPKEDLVVSASLDQTVRVW 135 R+WN +S+TC+ T H + +FHP + + SA D +V+ Sbjct: 731 RLWNLESKTCIQEFTAHRKKFEESIHDVAFHPSKCYIASAGADALAKVF 779 Score = 31.2 bits (69), Expect = 1.5 Identities = 16/63 (25%), Positives = 31/63 (49%) Frame = +1 Query: 268 VNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSN 447 +N HPTLP+ ++ +DR +K + N K + ++ H+ V+ + ++S Sbjct: 667 INRVISHPTLPISITAHEDRHIKFYDNNTGKL--IHSMVAHLEAVTSLAVDPNGLYLMSG 724 Query: 448 SED 456 S D Sbjct: 725 SHD 727 Score = 30.8 bits (68), Expect = 2.0 Identities = 11/34 (32%), Positives = 22/34 (64%) Frame = +1 Query: 40 LTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI 141 L H + +FHP E ++++AS D T+++W++ Sbjct: 459 LRSHFDGIRALAFHPIEPVLITASEDHTLKMWNL 492
>KI21A_HUMAN (Q7Z4S6) Kinesin family member 21A (Kinesin-like protein KIF2)| (NY-REN-62 antigen) Length = 1674 Score = 42.7 bits (99), Expect = 5e-04 Identities = 40/160 (25%), Positives = 68/160 (42%), Gaps = 23/160 (14%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCAS---FHPKEDLVVSASLDQTVRVWDIGALRKKTVSP 171 R+W+ + LTGH VMC + +DL+++ S D ++++D+ TVSP Sbjct: 1475 RMWDLKRFQSTGKLTGHLGPVMCLTVDQISSGQDLIITGSKDHYIKMFDVTEGALGTVSP 1534 Query: 172 A--------DDIMRLTQMNTDLFGGV--------DAVVKYVLE----GHDRGVNWASFHP 291 D I LT +LF G D K +L+ H V P Sbjct: 1535 THNFEPPHYDGIEALTIQGDNLFSGSRDNGIKKWDLTQKDLLQQVPNAHKDWVCALGVVP 1594 Query: 292 TLPLIVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCV 411 P+++SG +K+W M+ V ++GH + ++ + Sbjct: 1595 DHPVLLSGCRGGILKVWNMD--TFMPVGEMKGHDSPINAI 1632 Score = 30.8 bits (68), Expect = 2.0 Identities = 12/38 (31%), Positives = 22/38 (57%) Frame = +1 Query: 28 CVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI 141 C+ + GH V+C +DL+ + S D+T +VW++ Sbjct: 1339 CIHIAEGHTKAVLCVD--STDDLLFTGSKDRTCKVWNL 1374
>YJL2_YEAST (P47025) Hypothetical 80.0 kDa Trp-Asp repeats-containing protein| in ASF1-CCT7 intergenic region Length = 714 Score = 42.7 bits (99), Expect = 5e-04 Identities = 26/120 (21%), Positives = 50/120 (41%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 +IW+ + + L GH + C + +V+ D +++W++ A Sbjct: 424 KIWDLSKQNKIGELAGHLATINCMQINRDYGTLVTGGRDAALKLWNLNL--------AQQ 475 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTK 360 + + TQ T +D+ + E H V S P+ +VSG+ DR ++ W + K Sbjct: 476 LYQETQNLTSPTNHIDSPCVHTFEAHTDEVTALSLDPS--FLVSGSQDRTIRQWDLRSGK 533 Score = 33.9 bits (76), Expect = 0.23 Identities = 18/54 (33%), Positives = 28/54 (51%), Gaps = 2/54 (3%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI--GALRK 156 R+W+ +S + L GH + F +V+ S D+TVR+WD+ G L K Sbjct: 589 RLWDLRSGKVIRTLKGHTDAITSLKFDSA--CLVTGSYDRTVRIWDLRTGLLNK 640 Score = 30.4 bits (67), Expect = 2.6 Identities = 18/74 (24%), Positives = 34/74 (45%), Gaps = 1/74 (1%) Frame = +1 Query: 244 VLEGHDRGVNWASFH-PTLPLIVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFH 420 ++ HD + F P L +G D VK+W ++ K ++ L GH+ ++C+ + Sbjct: 393 IMSTHDDFLTCLDFDAPFGTLCTAGYLDHTVKIWDLS--KQNKIGELAGHLATINCMQIN 450 Query: 421 AKQDIIVSNSEDKA 462 +V+ D A Sbjct: 451 RDYGTLVTGGRDAA 464
>ESC_DROME (Q24338) Polycomb protein esc (Protein extra sex combs)| Length = 425 Score = 42.7 bits (99), Expect = 5e-04 Identities = 25/79 (31%), Positives = 42/79 (53%), Gaps = 2/79 (2%) Frame = +1 Query: 226 DAVVKYVLEGHDRGVNWASFHP-TLPLIVSGADDRQVKLWRMNDTKAWEV-DTLRGHMNN 399 +AV Y+ GH + +N FHP L L++SG+ D ++LW + + + GH + Sbjct: 161 EAVGNYI--GHGQAINELKFHPHKLQLLLSGSKDHAIRLWNIQSHVCIAILGGVEGHRDE 218 Query: 400 VSCVMFHAKQDIIVSNSED 456 V + F+ + D IVS+ D Sbjct: 219 VLSIDFNMRGDRIVSSGMD 237 Score = 42.4 bits (98), Expect = 7e-04 Identities = 17/48 (35%), Positives = 30/48 (62%), Gaps = 3/48 (6%) Frame = +1 Query: 1 RIWNWQSRTCVAVL---TGHNHYVMCASFHPKEDLVVSASLDQTVRVW 135 R+WN QS C+A+L GH V+ F+ + D +VS+ +D ++++W Sbjct: 196 RLWNIQSHVCIAILGGVEGHRDEVLSIDFNMRGDRIVSSGMDHSLKLW 243 Score = 35.0 bits (79), Expect = 0.10 Identities = 31/118 (26%), Positives = 46/118 (38%), Gaps = 1/118 (0%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHP-KEDLVVSASLDQTVRVWDIGALRKKTVSPAD 177 R+ + + V GH + FHP K L++S S D +R+W+I + Sbjct: 153 RVIDVEQNEAVGNYIGHGQAINELKFHPHKLQLLLSGSKDHAIRLWNIQS---------- 202 Query: 178 DIMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMN 351 + + GGV EGH V F+ IVS D +KLW +N Sbjct: 203 ------HVCIAILGGV--------EGHRDEVLSIDFNMRGDRIVSSGMDHSLKLWCLN 246
>STRN4_MOUSE (P58404) Striatin-4 (Zinedin)| Length = 760 Score = 42.7 bits (99), Expect = 5e-04 Identities = 36/164 (21%), Positives = 62/164 (37%), Gaps = 24/164 (14%) Frame = +1 Query: 37 VLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIG--------------------ALRK 156 VL GH V +F P + S S D TVR+WD ++ Sbjct: 546 VLEGHGDAVWGLAFSPTSQRLASCSADGTVRIWDPSSSGPSCLCTFPMAGEHGIPTSVAF 605 Query: 157 KTVSPADDIMRLTQMNTDLFGGVDAVVKYVLEGHDRG----VNWASFHPTLPLIVSGADD 324 + PA + +T L+ LE +N HP+ PL ++ DD Sbjct: 606 TSTEPAHVVASFRSGDTVLYDLEAGSALLTLESRGSSGPAQINQVVSHPSQPLTITAHDD 665 Query: 325 RQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 R ++ +++ V ++ H++ V+C+ ++S S D Sbjct: 666 RGIRF--LDNRTGKSVHSMVAHLDAVTCLAVDPNGVFLMSGSHD 707 Score = 36.6 bits (83), Expect = 0.036 Identities = 29/138 (21%), Positives = 54/138 (39%), Gaps = 37/138 (26%) Frame = +1 Query: 40 LTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDI------------ 183 L H + +FH + +++AS D T+++W++ + A D+ Sbjct: 441 LRSHYDGIRSLAFHHSQSALLTASEDGTLKLWNLQKAVTAKKNAALDVEPIHAFRAHRGP 500 Query: 184 ------------------------MRLTQMNTDLFGGVD-AVVKYVLEGHDRGVNWASFH 288 ++ +N D + G D +V+ +VLEGH V +F Sbjct: 501 VLAVTMGSNSEYCYSGGADARIHSWKIPDLNMDPYDGYDPSVLSHVLEGHGDAVWGLAFS 560 Query: 289 PTLPLIVSGADDRQVKLW 342 PT + S + D V++W Sbjct: 561 PTSQRLASCSADGTVRIW 578 Score = 33.5 bits (75), Expect = 0.30 Identities = 17/52 (32%), Positives = 26/52 (50%), Gaps = 7/52 (13%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHN-------HYVMCASFHPKEDLVVSASLDQTVRVW 135 R+W+ ++TCV +T H H V C HP + L+ SA D +V+ Sbjct: 711 RLWSLDNKTCVQEITAHRKKHEEAIHAVAC---HPSKALIASAGADALAKVF 759 Score = 28.9 bits (63), Expect = 7.5 Identities = 10/37 (27%), Positives = 21/37 (56%) Frame = +1 Query: 238 KYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRM 348 K+ L H G+ +FH + +++ ++D +KLW + Sbjct: 438 KFTLRSHYDGIRSLAFHHSQSALLTASEDGTLKLWNL 474
>PRP4_HUMAN (O43172) U4/U6 small nuclear ribonucleoprotein Prp4 (U4/U6 snRNP 60| kDa protein) (WD splicing factor Prp4) (hPrp4) Length = 522 Score = 42.7 bits (99), Expect = 5e-04 Identities = 36/163 (22%), Positives = 59/163 (36%), Gaps = 2/163 (1%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 R+W+ ++ C+ L GH + +F P + + S D T +VWD+ R Sbjct: 390 RVWDLRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRR--------- 440 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTL-PLIVSGADDRQVKLWRMNDT 357 Y + H V F P +++GA D K+W Sbjct: 441 ------------------CVYTIPAHQNLVTGVKFEPIHGNFLLTGAYDNTAKIW---TH 479 Query: 358 KAWE-VDTLRGHMNNVSCVMFHAKQDIIVSNSEDKAFASGMPQ 483 W + TL GH V + + +I + S D+ F M + Sbjct: 480 PGWSPLKTLAGHEGKVMGLDISSDGQLIATCSYDRTFKLWMAE 522 Score = 42.4 bits (98), Expect = 7e-04 Identities = 38/154 (24%), Positives = 63/154 (40%), Gaps = 15/154 (9%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPAD- 177 ++W+ S VA + GH V +HP + + D++ R+WD+ A + Sbjct: 306 KLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQEEILHQEGHS 365 Query: 178 ----DIMRLTQMNTDLFGGVDAVVK----------YVLEGHDRGVNWASFHPTLPLIVSG 315 DI + GG+DA + LEGH + + +F P I +G Sbjct: 366 MGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPNGYHIATG 425 Query: 316 ADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMF 417 + D K+W + + V T+ H N V+ V F Sbjct: 426 SGDNTCKVWDLRQRRC--VYTIPAHQNLVTGVKF 457 Score = 40.4 bits (93), Expect = 0.002 Identities = 19/61 (31%), Positives = 30/61 (49%) Frame = +1 Query: 253 GHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQD 432 G DR +++ F P ++ + KLW + D + TLRGH NV ++FH K Sbjct: 229 GDDRPISYCHFSPNSKMLATACWSGLCKLWSVPDCNL--LHTLRGHNTNVGAIVFHPKST 286 Query: 433 I 435 + Sbjct: 287 V 287 Score = 34.3 bits (77), Expect = 0.18 Identities = 33/148 (22%), Positives = 54/148 (36%), Gaps = 8/148 (5%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDL--------VVSASLDQTVRVWDIGALRK 156 ++W+ + L GHN V FHPK + + S + D +V++W + Sbjct: 256 KLWSVPDCNLLHTLRGHNTNVGAIVFHPKSTVSLDPKDVNLASCAADGSVKLWSL----- 310 Query: 157 KTVSPADDIMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVK 336 + P DI EGH V +HP+ + + DR + Sbjct: 311 DSDEPVADI----------------------EGHTVRVARVMWHPSGRFLGTTCYDRSWR 348 Query: 337 LWRMNDTKAWEVDTLRGHMNNVSCVMFH 420 LW + + E+ GH V + FH Sbjct: 349 LWDLEAQE--EILHQEGHSMGVYDIAFH 374 Score = 33.9 bits (76), Expect = 0.23 Identities = 25/88 (28%), Positives = 41/88 (46%), Gaps = 8/88 (9%) Frame = +1 Query: 226 DAVVKYVLEGHDRGVNWASFHP--TLPL------IVSGADDRQVKLWRMNDTKAWEVDTL 381 D + + L GH+ V FHP T+ L + S A D VKLW ++ + V + Sbjct: 262 DCNLLHTLRGHNTNVGAIVFHPKSTVSLDPKDVNLASCAADGSVKLWSLDSDE--PVADI 319 Query: 382 RGHMNNVSCVMFHAKQDIIVSNSEDKAF 465 GH V+ VM+H + + D+++ Sbjct: 320 EGHTVRVARVMWHPSGRFLGTTCYDRSW 347
>PRP4_PONPY (Q5NVD0) U4/U6 small nuclear ribonucleoprotein Prp4 (U4/U6 snRNP 60| kDa protein) (WD splicing factor Prp4) Length = 521 Score = 42.7 bits (99), Expect = 5e-04 Identities = 36/163 (22%), Positives = 59/163 (36%), Gaps = 2/163 (1%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 R+W+ ++ C+ L GH + +F P + + S D T +VWD+ R Sbjct: 389 RVWDLRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRR--------- 439 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTL-PLIVSGADDRQVKLWRMNDT 357 Y + H V F P +++GA D K+W Sbjct: 440 ------------------CVYTIPAHQNLVTGVKFEPIHGNFLLTGAYDNTAKIW---TH 478 Query: 358 KAWE-VDTLRGHMNNVSCVMFHAKQDIIVSNSEDKAFASGMPQ 483 W + TL GH V + + +I + S D+ F M + Sbjct: 479 PGWSPLKTLAGHEGKVMGLDISSDGQLIATCSYDRTFKLWMAE 521 Score = 42.4 bits (98), Expect = 7e-04 Identities = 38/154 (24%), Positives = 63/154 (40%), Gaps = 15/154 (9%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPAD- 177 ++W+ S VA + GH V +HP + + D++ R+WD+ A + Sbjct: 305 KLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQEEILHQEGHS 364 Query: 178 ----DIMRLTQMNTDLFGGVDAVVK----------YVLEGHDRGVNWASFHPTLPLIVSG 315 DI + GG+DA + LEGH + + +F P I +G Sbjct: 365 MGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPNGYHIATG 424 Query: 316 ADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMF 417 + D K+W + + V T+ H N V+ V F Sbjct: 425 SGDNTCKVWDLRQRRC--VYTIPAHQNLVTGVKF 456 Score = 40.8 bits (94), Expect = 0.002 Identities = 19/67 (28%), Positives = 32/67 (47%) Frame = +1 Query: 253 GHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQD 432 G DR +++ F P ++ + KLW + D + TLRGH NV ++FH K Sbjct: 228 GDDRPISYCHFSPNSKMLATACWSGLCKLWSVPDCNL--LHTLRGHNTNVGAIVFHPKST 285 Query: 433 IIVSNSE 453 + + + Sbjct: 286 VSLDQKD 292 Score = 35.4 bits (80), Expect = 0.080 Identities = 36/140 (25%), Positives = 58/140 (41%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 ++W+ + L GHN V FHPK + SLDQ D+ AD Sbjct: 255 KLWSVPDCNLLHTLRGHNTNVGAIVFHPKS----TVSLDQK----DVNL----ASCAADG 302 Query: 181 IMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTK 360 ++L +++D + V +EGH V +HP+ + + DR +LW + + Sbjct: 303 SVKLWSLDSD-----EPVAD--IEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQE 355 Query: 361 AWEVDTLRGHMNNVSCVMFH 420 E+ GH V + FH Sbjct: 356 --EILHQEGHSMGVYDIAFH 373 Score = 33.9 bits (76), Expect = 0.23 Identities = 25/88 (28%), Positives = 41/88 (46%), Gaps = 8/88 (9%) Frame = +1 Query: 226 DAVVKYVLEGHDRGVNWASFHP--TLPL------IVSGADDRQVKLWRMNDTKAWEVDTL 381 D + + L GH+ V FHP T+ L + S A D VKLW ++ + V + Sbjct: 261 DCNLLHTLRGHNTNVGAIVFHPKSTVSLDQKDVNLASCAADGSVKLWSLDSDE--PVADI 318 Query: 382 RGHMNNVSCVMFHAKQDIIVSNSEDKAF 465 GH V+ VM+H + + D+++ Sbjct: 319 EGHTVRVARVMWHPSGRFLGTTCYDRSW 346
>GBLP_BRARE (O42248) Guanine nucleotide-binding protein beta subunit 2-like 1| (Receptor of activated protein kinase C) (RACK) Length = 317 Score = 42.4 bits (98), Expect = 7e-04 Identities = 33/125 (26%), Positives = 55/125 (44%), Gaps = 18/125 (14%) Frame = +1 Query: 40 LTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI--GALRKKTVSPADDIMRL--TQMNT 207 L GH+H+V +S S D T+R+WD+ G ++ V D++ + + N Sbjct: 59 LRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSADNR 118 Query: 208 DLFGG----------VDAVVKYVL--EGHDRGVNWASFHP--TLPLIVSGADDRQVKLWR 345 + G V KY + + H V+ F P + P+IVS D+ VK+W Sbjct: 119 QIVSGSRDKTIKLWNTLGVCKYTIQDDSHTEWVSCVRFSPNSSNPIIVSCGWDKMVKVWN 178 Query: 346 MNDTK 360 + + K Sbjct: 179 LANCK 183 Score = 41.2 bits (95), Expect = 0.001 Identities = 33/138 (23%), Positives = 53/138 (38%), Gaps = 18/138 (13%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTV----- 165 R+W+ + T GH V+ +F +VS S D+T+++W+ + K T+ Sbjct: 88 RLWDLTTGTTTRRFVGHTKDVLSVAFSADNRQIVSGSRDKTIKLWNTLGVCKYTIQDDSH 147 Query: 166 ---------SPADDIMRLTQMNTDLFGGVDAVVKYVLE----GHDRGVNWASFHPTLPLI 306 SP + D V + L+ GH +N + P L Sbjct: 148 TEWVSCVRFSPNSSNPIIVSCGWDKMVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLC 207 Query: 307 VSGADDRQVKLWRMNDTK 360 SG D Q LW +N+ K Sbjct: 208 ASGGKDGQAMLWDLNEGK 225 Score = 39.7 bits (91), Expect = 0.004 Identities = 38/149 (25%), Positives = 61/149 (40%), Gaps = 1/149 (0%) Frame = +1 Query: 16 QSRTCVAVLTGHNHYVMCASFHPK-EDLVVSASLDQTVRVWDIGALRKKTVSPADDIMRL 192 + T L GH+ +V + P+ D+++SAS D+T+ +W +L Sbjct: 3 EQMTVRGTLKGHSGWVTQIATTPQFPDMILSASRDKTIIMW-----------------KL 45 Query: 193 TQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEV 372 T+ T+ + + L GH V+ +SG+ D ++LW + T Sbjct: 46 TRDETNY-----GIPQRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDL--TTGTTT 98 Query: 373 DTLRGHMNNVSCVMFHAKQDIIVSNSEDK 459 GH +V V F A IVS S DK Sbjct: 99 RRFVGHTKDVLSVAFSADNRQIVSGSRDK 127
>STRN4_HUMAN (Q9NRL3) Striatin-4 (Zinedin)| Length = 753 Score = 42.4 bits (98), Expect = 7e-04 Identities = 36/164 (21%), Positives = 61/164 (37%), Gaps = 24/164 (14%) Frame = +1 Query: 37 VLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIG--------------------ALRK 156 VL GH V +F P + S S D TVR+WD ++ Sbjct: 539 VLEGHGDAVWGLAFSPTSQRLASCSADGTVRIWDPSSSSPACLCTFPTASEHGVPTSVAF 598 Query: 157 KTVSPADDIMRLTQMNTDLFGGVDAVVKYVLEGHDRG----VNWASFHPTLPLIVSGADD 324 + PA + +T L+ LE +N HP PL ++ DD Sbjct: 599 TSTEPAHIVASFRSGDTVLYDMEVGSALLTLESRGSSGPTQINQVVSHPNQPLTITAHDD 658 Query: 325 RQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 R ++ +++ V ++ H++ V+C+ ++S S D Sbjct: 659 RGIRF--LDNRTGKPVHSMVAHLDAVTCLAVDPNGAFLMSGSHD 700 Score = 34.7 bits (78), Expect = 0.14 Identities = 28/138 (20%), Positives = 54/138 (39%), Gaps = 37/138 (26%) Frame = +1 Query: 40 LTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDI------------ 183 L H + +FH + +++AS D T+++W++ + A D+ Sbjct: 434 LRSHYDGIRSLAFHHSQSALLTASEDGTLKLWNLQKAVTAKKNAALDVEPIHAFRAHRGP 493 Query: 184 ------------------------MRLTQMNTDLFGGVD-AVVKYVLEGHDRGVNWASFH 288 ++ ++ D + G D +V+ +VLEGH V +F Sbjct: 494 VLAVAMGSNSEYCYSGGADACIHSWKIPDLSMDPYDGYDPSVLSHVLEGHGDAVWGLAFS 553 Query: 289 PTLPLIVSGADDRQVKLW 342 PT + S + D V++W Sbjct: 554 PTSQRLASCSADGTVRIW 571 Score = 33.5 bits (75), Expect = 0.30 Identities = 17/52 (32%), Positives = 26/52 (50%), Gaps = 7/52 (13%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHN-------HYVMCASFHPKEDLVVSASLDQTVRVW 135 R+W+ ++TCV +T H H V C HP + L+ SA D +V+ Sbjct: 704 RLWSLDNKTCVQEITAHRKKHEEAIHAVAC---HPSKALIASAGADALAKVF 752 Score = 29.3 bits (64), Expect = 5.7 Identities = 19/87 (21%), Positives = 35/87 (40%), Gaps = 9/87 (10%) Frame = +1 Query: 238 KYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRM------NDTKAWEVDTL---RGH 390 K+ L H G+ +FH + +++ ++D +KLW + A +V+ + R H Sbjct: 431 KFTLRSHYDGIRSLAFHHSQSALLTASEDGTLKLWNLQKAVTAKKNAALDVEPIHAFRAH 490 Query: 391 MNNVSCVMFHAKQDIIVSNSEDKAFAS 471 V V + + S D S Sbjct: 491 RGPVLAVAMGSNSEYCYSGGADACIHS 517
>ESC_DROVI (Q26458) Polycomb protein esc (Protein extra sex combs)| Length = 425 Score = 42.4 bits (98), Expect = 7e-04 Identities = 25/79 (31%), Positives = 42/79 (53%), Gaps = 2/79 (2%) Frame = +1 Query: 226 DAVVKYVLEGHDRGVNWASFHP-TLPLIVSGADDRQVKLWRMNDTKAWEV-DTLRGHMNN 399 +AV Y+ GH + +N FHP L L++SG+ D ++LW + + + GH + Sbjct: 161 EAVDNYI--GHGQAINELKFHPHKLQLLLSGSKDHAIRLWNIQTHVCIAIFGGVEGHRDE 218 Query: 400 VSCVMFHAKQDIIVSNSED 456 V + F+ + D IVS+ D Sbjct: 219 VLSIDFNMRGDRIVSSGMD 237 Score = 40.0 bits (92), Expect = 0.003 Identities = 15/48 (31%), Positives = 30/48 (62%), Gaps = 3/48 (6%) Frame = +1 Query: 1 RIWNWQSRTCVAV---LTGHNHYVMCASFHPKEDLVVSASLDQTVRVW 135 R+WN Q+ C+A+ + GH V+ F+ + D +VS+ +D ++++W Sbjct: 196 RLWNIQTHVCIAIFGGVEGHRDEVLSIDFNMRGDRIVSSGMDHSLKLW 243 Score = 38.1 bits (87), Expect = 0.012 Identities = 33/118 (27%), Positives = 47/118 (39%), Gaps = 1/118 (0%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHP-KEDLVVSASLDQTVRVWDIGALRKKTVSPAD 177 R+ + + V GH + FHP K L++S S D +R+W+I Sbjct: 153 RVIDIEQNEAVDNYIGHGQAINELKFHPHKLQLLLSGSKDHAIRLWNIQ----------- 201 Query: 178 DIMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMN 351 T + +FGGV EGH V F+ IVS D +KLW +N Sbjct: 202 -----THVCIAIFGGV--------EGHRDEVLSIDFNMRGDRIVSSGMDHSLKLWCLN 246
>LIN53_CAEEL (P90916) Probable histone-binding protein lin-53 (Abnormal cell| lineage protein 53) Length = 417 Score = 42.4 bits (98), Expect = 7e-04 Identities = 43/163 (26%), Positives = 75/163 (46%), Gaps = 26/163 (15%) Frame = +1 Query: 40 LTGHNHYVMCASFHP-KEDLVVSASLDQTVRVWDI-------GALRKKTV-----SPADD 180 L GH S++P KE L++SAS DQTV WDI G L+ K V S +D Sbjct: 168 LKGHTKEGYGLSWNPNKEGLILSASDDQTVCHWDINANQNVAGELQAKDVFKGHESVVED 227 Query: 181 IMRLTQMNTDLFGGVDAVVK------------YVLEGHDRGVNWASFHPTLPLIV-SGAD 321 + ++ +FG V K + ++ H VN +F+P I+ +G+ Sbjct: 228 V-AWHVLHDGVFGSVGDDKKLLIWDVRTSTPGHCIDAHSAEVNCLAFNPYSEFILATGSA 286 Query: 322 DRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNS 450 D+ V LW + + + ++ + H + + V + + I+++S Sbjct: 287 DKTVALWDLRNLR-MKLHSFESHRDEIFQVQWSPHNETILASS 328 Score = 39.3 bits (90), Expect = 0.006 Identities = 40/157 (25%), Positives = 69/157 (43%), Gaps = 33/157 (21%) Frame = +1 Query: 4 IWNWQSRTCVAVLTGHNHYVMCASFHP-KEDLVVSASLDQTVRVWDIGALRKKT---VSP 171 IW+ ++ T + H+ V C +F+P E ++ + S D+TV +WD+ LR K S Sbjct: 249 IWDVRTSTPGHCIDAHSAEVNCLAFNPYSEFILATGSADKTVALWDLRNLRMKLHSFESH 308 Query: 172 ADDIMR----------LTQMNTDLFGGVDAVVK------------------YVLEGHDRG 267 D+I + L TD V + K ++ GH Sbjct: 309 RDEIFQVQWSPHNETILASSGTDKRLHVWDLSKIGEDQSAEDAEDGPPELLFIHGGHTAK 368 Query: 268 VNWASFHPTLPLIV-SGADDRQVKLWRMNDTKAWEVD 375 ++ S++P P +V S ++D +++W+M D EVD Sbjct: 369 ISDFSWNPNEPWVVCSVSEDNILQVWQMADNIYNEVD 405
>RBBP4_MOUSE (Q60972) Histone-binding protein RBBP4 (Retinoblastoma-binding| protein 4) (RBBP-4) (Retinoblastoma-binding protein p48) (Chromatin assembly factor 1 subunit C) (CAF-1 subunit C) (Chromatin assembly factor I p48 subunit) (CAF-I 48 kDa subunit) Length = 424 Score = 42.0 bits (97), Expect = 9e-04 Identities = 43/147 (29%), Positives = 69/147 (46%), Gaps = 4/147 (2%) Frame = +1 Query: 40 LTGHNHYVMCASFHPK-EDLVVSASLDQTVRVWDIGALRKKTVSPADDIMRLTQMNTDLF 216 L GH S++P ++SAS D T+ +WDI A+ KK ++ T +F Sbjct: 172 LRGHQKEGYGLSWNPNLSGHLLSASDDHTICLWDISAVPKKG--------KVVDAKT-IF 222 Query: 217 GGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLW--RMNDTKAWEVDTLRGH 390 G AVV+ V+W H + L S ADD+++ +W R N+T ++ H Sbjct: 223 TGHTAVVE--------DVSWHLLHES--LFGSVADDQKLMIWDTRSNNTSK-PSHSVDAH 271 Query: 391 MNNVSCVMFHAKQD-IIVSNSEDKAFA 468 V+C+ F+ + I+ + S DK A Sbjct: 272 TAEVNCLSFNPYSEFILATGSADKTVA 298 Score = 31.2 bits (69), Expect = 1.5 Identities = 15/38 (39%), Positives = 23/38 (60%), Gaps = 1/38 (2%) Frame = +1 Query: 49 HNHYVMCASFHP-KEDLVVSASLDQTVRVWDIGALRKK 159 H V C SF+P E ++ + S D+TV +WD+ L+ K Sbjct: 271 HTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLK 308
>FZR_MOUSE (Q9R1K5) Fizzy-related protein homolog (Fzr) (Cdh1/Hct1 homolog)| Length = 493 Score = 42.0 bits (97), Expect = 9e-04 Identities = 17/53 (32%), Positives = 33/53 (62%) Frame = +1 Query: 4 IWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKT 162 +W + S T VA LTGH++ V+ + P + +V+ + D+T+R W++ + + T Sbjct: 427 VWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFSKTRST 479
>FZR_HUMAN (Q9UM11) Fizzy-related protein homolog (Fzr) (Cdh1/Hct1 homolog)| (hCDH1) (CDC20-like protein 1) Length = 496 Score = 42.0 bits (97), Expect = 9e-04 Identities = 17/53 (32%), Positives = 33/53 (62%) Frame = +1 Query: 4 IWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKT 162 +W + S T VA LTGH++ V+ + P + +V+ + D+T+R W++ + + T Sbjct: 427 VWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFSKTRST 479
>A16L1_MOUSE (Q8C0J2) Autophagy-related protein 16-1 (APG16-like 1)| Length = 607 Score = 42.0 bits (97), Expect = 9e-04 Identities = 24/80 (30%), Positives = 36/80 (45%) Frame = +1 Query: 223 VDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNV 402 V YV + HD VN F P L+ +G DR+VKLW K +L G + Sbjct: 310 VPTTASYVFDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEAFGDKCEFKGSLSGSNAGI 369 Query: 403 SCVMFHAKQDIIVSNSEDKA 462 + + F + +++ S D A Sbjct: 370 TSIEFDSAGAYLLAASNDFA 389 Score = 35.4 bits (80), Expect = 0.080 Identities = 33/145 (22%), Positives = 54/145 (37%), Gaps = 17/145 (11%) Frame = +1 Query: 25 TCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWD-IGALRKKTVSPADDIMRLTQM 201 T V H+ V F P L+ + +D+ V++W+ G + S + +T + Sbjct: 313 TASYVFDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEAFGDKCEFKGSLSGSNAGITSI 372 Query: 202 NTDLFGGV----------------DAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQV 333 D G D +++ L GH V A F IVSG+ DR + Sbjct: 373 EFDSAGAYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTL 432 Query: 334 KLWRMNDTKAWEVDTLRGHMNNVSC 408 KLW + + N++ C Sbjct: 433 KLWDLRSKVCIKTVFAGSSCNDIVC 457 Score = 35.0 bits (79), Expect = 0.10 Identities = 17/47 (36%), Positives = 25/47 (53%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI 141 RIW LTGH+ V+ A F +VS S D+T+++WD+ Sbjct: 391 RIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDL 437
>YEP6_YEAST (P40042) Hypothetical 20.7 kDa Trp-Asp repeats-containing protein| in ICL1-NOT4 intergenic region Length = 185 Score = 42.0 bits (97), Expect = 9e-04 Identities = 32/150 (21%), Positives = 56/150 (37%), Gaps = 8/150 (5%) Frame = +1 Query: 28 CVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRK--------KTVSPADDI 183 C+ +L+GH + + + +SAS+D T+R+WD+ +R + SP I Sbjct: 3 CLYILSGHTDRIYSTIYDHERKRCISASMDTTIRIWDLENIRNNGECSYATNSASPCAKI 62 Query: 184 MRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKA 363 + Y L GH V +VS + D ++ W D Sbjct: 63 LG---------------AMYTLRGHRALVGLLGLSD--KFLVSASVDGSIRCW---DANT 102 Query: 364 WEVDTLRGHMNNVSCVMFHAKQDIIVSNSE 453 + + H + H +++VS SE Sbjct: 103 YFLKHFFDHTQLNTITALHVSDEVLVSGSE 132
>TBL1R_MOUSE (Q8BHJ5) F-box-like/WD-repeat protein TBL1XR1 (Transducin beta-like| 1X-related protein 1) (Nuclear receptor corepressor/HDAC3 complex subunit TBLR1) (TBL1-related protein 1) Length = 514 Score = 42.0 bits (97), Expect = 9e-04 Identities = 37/149 (24%), Positives = 61/149 (40%), Gaps = 15/149 (10%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTV----- 165 RIW + + L H + ++ K + ++SA +D+T +WD K Sbjct: 250 RIWT-KDGNLASTLGQHKGPIFALKWNKKGNFILSAGVDKTTIIWDAHTGEAKQQFPFHS 308 Query: 166 SPADDI-----MRLTQMNTDLFG-----GVDAVVKYVLEGHDRGVNWASFHPTLPLIVSG 315 +PA D+ +TD+ G D +K +GH VN + PT L+ S Sbjct: 309 APALDVDWQSNNTFASCSTDMCIHVCKLGQDRPIK-TFQGHTNEVNAIKWDPTGNLLASC 367 Query: 316 ADDRQVKLWRMNDTKAWEVDTLRGHMNNV 402 +DD +K+W M V L+ H + Sbjct: 368 SDDMTLKIWSMKQDNC--VHDLQAHNKEI 394 Score = 40.8 bits (94), Expect = 0.002 Identities = 34/141 (24%), Positives = 60/141 (42%) Frame = +1 Query: 37 VLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDIMRLTQMNTDLF 216 VL GH V +++P DL+ S S D T R+W++ T P ++R + Sbjct: 164 VLRGHESEVFICAWNPVSDLLASGSGDSTARIWNLS--ENSTSGPTQLVLR----HCIRE 217 Query: 217 GGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVDTLRGHMN 396 GG D ++ V ++ L+ +G+ D ++W + A TL H Sbjct: 218 GGQDV-------PSNKDVTSLDWNSEGTLLATGSYDGFARIWTKDGNLA---STLGQHKG 267 Query: 397 NVSCVMFHAKQDIIVSNSEDK 459 + + ++ K + I+S DK Sbjct: 268 PIFALKWNKKGNFILSAGVDK 288 Score = 35.4 bits (80), Expect = 0.080 Identities = 27/123 (21%), Positives = 43/123 (34%), Gaps = 9/123 (7%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKED---------LVVSASLDQTVRVWDIGALR 153 +IW+ + CV L HN + + P ++ SAS D TVR+WD+ Sbjct: 374 KIWSMKQDNCVHDLQAHNKEIYTIKWSPTGPGTNNPNANLMLASASFDSTVRLWDVDR-- 431 Query: 154 KKTVSPADDIMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQV 333 + + L H V +F P + SG+ D+ V Sbjct: 432 -------------------------GICIHTLTKHQEPVYSVAFSPDGRYLASGSFDKCV 466 Query: 334 KLW 342 +W Sbjct: 467 HIW 469 Score = 34.3 bits (77), Expect = 0.18 Identities = 14/46 (30%), Positives = 22/46 (47%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWD 138 R+W+ C+ LT H V +F P + S S D+ V +W+ Sbjct: 425 RLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWN 470
>TBL1R_HUMAN (Q9BZK7) F-box-like/WD-repeat protein TBL1XR1 (Transducin beta-like| 1X-related protein 1) (Nuclear receptor corepressor/HDAC3 complex subunit TBLR1) (TBL1-related protein 1) Length = 514 Score = 42.0 bits (97), Expect = 9e-04 Identities = 37/149 (24%), Positives = 61/149 (40%), Gaps = 15/149 (10%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTV----- 165 RIW + + L H + ++ K + ++SA +D+T +WD K Sbjct: 250 RIWT-KDGNLASTLGQHKGPIFALKWNKKGNFILSAGVDKTTIIWDAHTGEAKQQFPFHS 308 Query: 166 SPADDI-----MRLTQMNTDLFG-----GVDAVVKYVLEGHDRGVNWASFHPTLPLIVSG 315 +PA D+ +TD+ G D +K +GH VN + PT L+ S Sbjct: 309 APALDVDWQSNNTFASCSTDMCIHVCKLGQDRPIK-TFQGHTNEVNAIKWDPTGNLLASC 367 Query: 316 ADDRQVKLWRMNDTKAWEVDTLRGHMNNV 402 +DD +K+W M V L+ H + Sbjct: 368 SDDMTLKIWSMKQDNC--VHDLQAHNKEI 394 Score = 37.7 bits (86), Expect = 0.016 Identities = 32/141 (22%), Positives = 59/141 (41%) Frame = +1 Query: 37 VLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDIMRLTQMNTDLF 216 VL GH V +++P DL+ S S D T R+W++ + + +L + Sbjct: 164 VLRGHESEVFICAWNPVSDLLASGSGDSTARIWNL------SENSTSGSTQLVLRHCIRE 217 Query: 217 GGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVDTLRGHMN 396 GG D ++ V ++ L+ +G+ D ++W + A TL H Sbjct: 218 GGQDV-------PSNKDVTSLDWNSEGTLLATGSYDGFARIWTKDGNLA---STLGQHKG 267 Query: 397 NVSCVMFHAKQDIIVSNSEDK 459 + + ++ K + I+S DK Sbjct: 268 PIFALKWNKKGNFILSAGVDK 288 Score = 35.4 bits (80), Expect = 0.080 Identities = 27/123 (21%), Positives = 43/123 (34%), Gaps = 9/123 (7%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKED---------LVVSASLDQTVRVWDIGALR 153 +IW+ + CV L HN + + P ++ SAS D TVR+WD+ Sbjct: 374 KIWSMKQDNCVHDLQAHNKEIYTIKWSPTGPGTNNPNANLMLASASFDSTVRLWDVDR-- 431 Query: 154 KKTVSPADDIMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQV 333 + + L H V +F P + SG+ D+ V Sbjct: 432 -------------------------GICIHTLTKHQEPVYSVAFSPDGRYLASGSFDKCV 466 Query: 334 KLW 342 +W Sbjct: 467 HIW 469 Score = 34.3 bits (77), Expect = 0.18 Identities = 14/46 (30%), Positives = 22/46 (47%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWD 138 R+W+ C+ LT H V +F P + S S D+ V +W+ Sbjct: 425 RLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWN 470
>TBLX_MOUSE (Q9QXE7) F-box-like/WD-repeat protein TBL1X (Transducin beta-like| 1X protein) Length = 527 Score = 42.0 bits (97), Expect = 9e-04 Identities = 37/149 (24%), Positives = 57/149 (38%), Gaps = 15/149 (10%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADD 180 RIW + + L H + ++ K + ++SA +D+T +WD K P Sbjct: 263 RIWT-EDGNLASTLGQHKGPIFALKWNKKGNYILSAGVDKTTIIWDAHTGEAKQQFPFHS 321 Query: 181 IMRLT---QMNTDLFG------------GVDAVVKYVLEGHDRGVNWASFHPTLPLIVSG 315 L Q NT G D VK +GH VN + P+ L+ S Sbjct: 322 APALDVDWQNNTTFASCSTDMCIHVCRLGCDRPVK-TFQGHTNEVNAIKWDPSGMLLASC 380 Query: 316 ADDRQVKLWRMNDTKAWEVDTLRGHMNNV 402 +DD +K+W M V L+ H + Sbjct: 381 SDDMTLKIWSMKQDAC--VHDLQAHSKEI 407 Score = 38.1 bits (87), Expect = 0.012 Identities = 33/147 (22%), Positives = 59/147 (40%), Gaps = 6/147 (4%) Frame = +1 Query: 37 VLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDIMRLTQMNTDLF 216 VL GH V +++P DL+ S S D T R+W++ Sbjct: 177 VLRGHESEVFICAWNPVSDLLASGSGDSTARIWNLN-------------------ENSNG 217 Query: 217 GGVDAVVKYVLE--GHD----RGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVDT 378 G V+++ + GHD + V ++ L+ +G+ D ++W + A T Sbjct: 218 GSTQLVLRHCIREGGHDVPSNKDVTSLDWNSDGTLLATGSYDGFARIWTEDGNLA---ST 274 Query: 379 LRGHMNNVSCVMFHAKQDIIVSNSEDK 459 L H + + ++ K + I+S DK Sbjct: 275 LGQHKGPIFALKWNKKGNYILSAGVDK 301 Score = 35.8 bits (81), Expect = 0.061 Identities = 14/46 (30%), Positives = 23/46 (50%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWD 138 R+W+ + C+ LT H V +F P + S S D+ V +W+ Sbjct: 438 RLWDVERGVCIHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWN 483 Score = 35.8 bits (81), Expect = 0.061 Identities = 35/161 (21%), Positives = 60/161 (37%), Gaps = 9/161 (5%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHP---------KEDLVVSASLDQTVRVWDIGALR 153 +IW+ + CV L H+ + + P ++ SAS D TVR+WD+ Sbjct: 387 KIWSMKQDACVHDLQAHSKEIYTIKWSPTGPATSNPNSNIMLASASFDSTVRLWDVER-- 444 Query: 154 KKTVSPADDIMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQV 333 V + L H V +F P + SG+ D+ V Sbjct: 445 -------------------------GVCIHTLTKHQEPVYSVAFSPDGKYLASGSFDKCV 479 Query: 334 KLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 +W N V + RG + V ++A+ D + +++ D Sbjct: 480 HIW--NTQSGSLVHSYRG-TGGIFEVCWNARGDKVGASASD 517
>WDR71_CHICK (Q5ZK69) WD-repeat protein 71| Length = 392 Score = 42.0 bits (97), Expect = 9e-04 Identities = 28/118 (23%), Positives = 44/118 (37%) Frame = +1 Query: 49 HNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDIMRLTQMNTDLFGGVD 228 H + C L VS S D T+++W + Sbjct: 91 HQKSITCLDISSGGGLGVSTSTDGTMKIWQ---------------------------AAN 123 Query: 229 AVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNV 402 ++ +LEGH VN F P+ +++SG D Q+K+W D V T +GH + Sbjct: 124 GEIRRLLEGHVYDVNCCRFFPSGLVVLSGGMDAQLKIWSAEDASC--VVTFKGHKGGI 179 Score = 35.4 bits (80), Expect = 0.080 Identities = 15/48 (31%), Positives = 25/48 (52%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIG 144 +IW+ + +CV GH ++ + + V+S S D T R+WD G Sbjct: 159 KIWSAEDASCVVTFKGHKGGILDTAIVDRGRNVLSCSRDGTARLWDCG 206 Score = 31.2 bits (69), Expect = 1.5 Identities = 13/45 (28%), Positives = 23/45 (51%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVW 135 +IW + +L GH + V C F P +V+S +D +++W Sbjct: 117 KIWQAANGEIRRLLEGHVYDVNCCRFFPSGLVVLSGGMDAQLKIW 161
>ATG16_XENTR (Q5I0B9) Autophagy-related protein 16 (APG16-like 1)| Length = 537 Score = 42.0 bits (97), Expect = 9e-04 Identities = 24/80 (30%), Positives = 37/80 (46%) Frame = +1 Query: 223 VDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNV 402 V A Y + HD VN F P L+ +G DR+VKLW + K +L G + Sbjct: 240 VPATAVYSFDAHDGEVNAVRFSPGSRLLATGGMDRRVKLWDVIGNKCEAKGSLTGSNAGI 299 Query: 403 SCVMFHAKQDIIVSNSEDKA 462 + + F + +++ S D A Sbjct: 300 TSIEFDSAGSYLLAASNDFA 319 Score = 38.5 bits (88), Expect = 0.009 Identities = 35/145 (24%), Positives = 54/145 (37%), Gaps = 17/145 (11%) Frame = +1 Query: 25 TCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWD-IGALRKKTVSPADDIMRLTQM 201 T V H+ V F P L+ + +D+ V++WD IG + S +T + Sbjct: 243 TAVYSFDAHDGEVNAVRFSPGSRLLATGGMDRRVKLWDVIGNKCEAKGSLTGSNAGITSI 302 Query: 202 NTDLFGGV----------------DAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQV 333 D G D +++ L GH V A F IVSG+ DR + Sbjct: 303 EFDSAGSYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTL 362 Query: 334 KLWRMNDTKAWEVDTLRGHMNNVSC 408 KLW + + N++ C Sbjct: 363 KLWDLRSKVCIKTVFAGSSCNDIVC 387 Score = 35.0 bits (79), Expect = 0.10 Identities = 17/47 (36%), Positives = 25/47 (53%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI 141 RIW LTGH+ V+ A F +VS S D+T+++WD+ Sbjct: 321 RIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDL 367
>LEUNG_ARATH (Q9FUY2) Transcriptional corepressor LEUNIG| Length = 931 Score = 41.6 bits (96), Expect = 0.001 Identities = 37/155 (23%), Positives = 66/155 (42%), Gaps = 15/155 (9%) Frame = +1 Query: 1 RIWNWQSRT-CVAVLTGHNHYVMCASFHP-KEDLVVSASLDQTVRVWDI--GALRKKTVS 168 R+W+ ++ + GH+ V FHP K+DL+ S D +R W I G+ + Sbjct: 718 RVWDADNKGYSLRTFMGHSSMVTSLDFHPIKDDLICSCDNDNEIRYWSINNGSCTRVYKG 777 Query: 169 PADDI-------MRLTQMNTDLFGGVDA---VVKYVLEGHDRGVNWASFHPTLPLIVSGA 318 + I L + +L +D +++ L+GH +N + P+ + S + Sbjct: 778 GSTQIRFQPRVGKYLAASSANLVNVLDVETQAIRHSLQGHANPINSVCWDPSGDFLASVS 837 Query: 319 DDRQVKLWRMNDTKAWE-VDTLRGHMNNVSCVMFH 420 +D VK+W + E V L + N +FH Sbjct: 838 ED-MVKVWTLGTGSEGECVHELSCNGNKFQSCVFH 871 Score = 36.2 bits (82), Expect = 0.047 Identities = 30/133 (22%), Positives = 50/133 (37%), Gaps = 1/133 (0%) Frame = +1 Query: 61 VMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDIMRLTQMNTDLFGGVDAVVK 240 V C F ++ SA D+ +W ++ KT Sbjct: 654 VTCCHFSSDGKMLASAGHDKKAVLWYTDTMKPKTT------------------------- 688 Query: 241 YVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFH 420 LE H + F P+ + + + D+ V++W D K + + T GH + V+ + FH Sbjct: 689 --LEEHTAMITDIRFSPSQLRLATSSFDKTVRVWDA-DNKGYSLRTFMGHSSMVTSLDFH 745 Query: 421 -AKQDIIVSNSED 456 K D+I S D Sbjct: 746 PIKDDLICSCDND 758 Score = 31.6 bits (70), Expect = 1.2 Identities = 39/189 (20%), Positives = 63/189 (33%), Gaps = 38/189 (20%) Frame = +1 Query: 4 IWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDI 183 +W + L H + F P + + ++S D+TVRVWD AD+ Sbjct: 677 LWYTDTMKPKTTLEEHTAMITDIRFSPSQLRLATSSFDKTVRVWD-----------ADN- 724 Query: 184 MRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTL-PLIVSGADDRQVKLWRMNDTK 360 + + T + GH V FHP LI S +D +++ W +N+ Sbjct: 725 -KGYSLRTFM-------------GHSSMVTSLDFHPIKDDLICSCDNDNEIRYWSINNGS 770 Query: 361 AWEV-------------------------------------DTLRGHMNNVSCVMFHAKQ 429 V +L+GH N ++ V + Sbjct: 771 CTRVYKGGSTQIRFQPRVGKYLAASSANLVNVLDVETQAIRHSLQGHANPINSVCWDPSG 830 Query: 430 DIIVSNSED 456 D + S SED Sbjct: 831 DFLASVSED 839
>KI21A_MOUSE (Q9QXL2) Kinesin family member 21A| Length = 1672 Score = 41.6 bits (96), Expect = 0.001 Identities = 40/160 (25%), Positives = 67/160 (41%), Gaps = 23/160 (14%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHP---KEDLVVSASLDQTVRVWDIGALRKKTVSP 171 R+W+ + LTGH VMC + +DL+++ S D ++++D+ TVSP Sbjct: 1473 RMWDLKRFQSTGKLTGHLGPVMCLTVDQISNGQDLIITGSKDHYIKMFDVTEGALGTVSP 1532 Query: 172 A--------DDIMRLTQMNTDLFGG------------VDAVVKYVLEGHDRGVNWASFHP 291 D I L +LF G +++ V H V P Sbjct: 1533 THNFEPPHYDGIEALAIQGDNLFSGSRDNGIKKWDLAQKGLLQQVPNAHKDWVCALGLVP 1592 Query: 292 TLPLIVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCV 411 P+++SG +KLW + DT V +RGH + ++ + Sbjct: 1593 GHPVLLSGCRGGILKLWNV-DTFV-PVGEMRGHDSPINAI 1630 Score = 31.2 bits (69), Expect = 1.5 Identities = 13/38 (34%), Positives = 22/38 (57%) Frame = +1 Query: 28 CVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI 141 CV + GH V+C +DL+ + S D+T +VW++ Sbjct: 1337 CVHIAEGHTKAVLCVD--STDDLLFTGSKDRTCKVWNL 1372
>CORO7_MOUSE (Q9D2V7) Coronin-7 (70 kDa WD repeat tumor rejection antigen| homolog) Length = 922 Score = 41.6 bits (96), Expect = 0.001 Identities = 24/55 (43%), Positives = 30/55 (54%), Gaps = 3/55 (5%) Frame = +1 Query: 37 VLTGHNHYVMCASFHP-KEDLVVSASLDQTVRVWDI--GALRKKTVSPADDIMRL 192 VLTGH + FHP D++ S+S D TVR+WD+ GA R K D I L Sbjct: 586 VLTGHTEKIYSLRFHPLAADVLASSSYDLTVRIWDLQTGAERLKLQGHQDQIFSL 640 Score = 32.7 bits (73), Expect = 0.52 Identities = 31/149 (20%), Positives = 59/149 (39%), Gaps = 1/149 (0%) Frame = +1 Query: 16 QSRTCVAVLTGHNHYVMCASFHPKED-LVVSASLDQTVRVWDIGALRKKTVSPADDIMRL 192 +++ V L H+ V F P +D L+ S S D+T+++W + + Sbjct: 65 ENKRHVTYLGCHSDLVTDLDFSPFDDFLLASGSADRTIKLWRLSGTGE------------ 112 Query: 193 TQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEV 372 + +V VL + V FHPT+ ++ + VK+W + K + Sbjct: 113 ---------ALPSVPGVVLGPEELPVEVLQFHPTVDGVLVSTAGKTVKVWDV--AKQQPL 161 Query: 373 DTLRGHMNNVSCVMFHAKQDIIVSNSEDK 459 L H + V ++ I+ + +DK Sbjct: 162 TELEAHKDLVQSAVWSRDGAIVGTACKDK 190 Score = 28.9 bits (63), Expect = 7.5 Identities = 18/51 (35%), Positives = 25/51 (49%), Gaps = 14/51 (27%) Frame = +1 Query: 247 LEGHD---RGVNWASFHPTLP-----------LIVSGADDRQVKLWRMNDT 357 LEGH+ R V + H L L+ SG+ DR +KLWR++ T Sbjct: 60 LEGHEENKRHVTYLGCHSDLVTDLDFSPFDDFLLASGSADRTIKLWRLSGT 110
>TB1RA_XENLA (Q7SZM9) F-box-like/WD-repeat-containing protein TBL1XR1-A| (Transducin beta-like 1X-related protein 1-A) (Nuclear receptor corepressor/HDAC3 complex subunit TBLR1-A) (TBL1-related protein 1-A) (xTBLR1) Length = 519 Score = 41.2 bits (95), Expect = 0.001 Identities = 34/131 (25%), Positives = 56/131 (42%), Gaps = 15/131 (11%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTV----- 165 RIW + + L H + ++ K + ++SA +D+T +WD K Sbjct: 255 RIWT-KDGNLASTLGQHKGPIFALKWNKKGNFILSAGVDKTTIIWDAHTGEAKQQFPFHS 313 Query: 166 SPADDI-----MRLTQMNTDLFG-----GVDAVVKYVLEGHDRGVNWASFHPTLPLIVSG 315 +PA D+ +TD+ G D +K +GH VN + PT L+ S Sbjct: 314 APALDVDWQSNNTFASCSTDMCIHVCKLGQDRPIK-TFQGHTNEVNAIKWDPTGNLLASC 372 Query: 316 ADDRQVKLWRM 348 +DD +K+W M Sbjct: 373 SDDMTLKIWSM 383 Score = 37.7 bits (86), Expect = 0.016 Identities = 32/141 (22%), Positives = 59/141 (41%) Frame = +1 Query: 37 VLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDIMRLTQMNTDLF 216 VL GH V +++P DL+ S S D T R+W++ + + +L + Sbjct: 169 VLRGHESEVFICAWNPVSDLLASGSGDSTARIWNL------SENSTSGSTQLVLRHCIRE 222 Query: 217 GGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVDTLRGHMN 396 GG D ++ V ++ L+ +G+ D ++W + A TL H Sbjct: 223 GGQDV-------PSNKDVTSLDWNSEGTLLATGSYDGFARIWTKDGNLA---STLGQHKG 272 Query: 397 NVSCVMFHAKQDIIVSNSEDK 459 + + ++ K + I+S DK Sbjct: 273 PIFALKWNKKGNFILSAGVDK 293 Score = 37.0 bits (84), Expect = 0.027 Identities = 28/123 (22%), Positives = 44/123 (35%), Gaps = 9/123 (7%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKED---------LVVSASLDQTVRVWDIGALR 153 +IW+ + TCV L HN + + P ++ SAS D TVR+WD+ Sbjct: 379 KIWSMKHDTCVHDLQAHNKEIYTIKWSPTGPGTNNPNANLMLASASFDSTVRLWDVDR-- 436 Query: 154 KKTVSPADDIMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQV 333 + + L H V +F P + SG+ D+ V Sbjct: 437 -------------------------GICIHTLTKHQEPVYSVAFSPDGRYLASGSFDKCV 471 Query: 334 KLW 342 +W Sbjct: 472 HIW 474 Score = 34.3 bits (77), Expect = 0.18 Identities = 14/46 (30%), Positives = 22/46 (47%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWD 138 R+W+ C+ LT H V +F P + S S D+ V +W+ Sbjct: 430 RLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWN 475
>GBB1_CAEEL (P17343) Guanine nucleotide-binding protein beta subunit 1| Length = 340 Score = 41.2 bits (95), Expect = 0.001 Identities = 36/153 (23%), Positives = 60/153 (39%), Gaps = 17/153 (11%) Frame = +1 Query: 4 IWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI-GALRKKTV----S 168 +W+ ++ TGH VM S P +S + D + ++WDI + K+T S Sbjct: 168 LWDIETGQQCTAFTGHTGDVMSLSLSPDFRTFISGACDASAKLWDIRDGMCKQTFPGHES 227 Query: 169 PADDIMRLTQMNTDLFGGVDAVVK---------YVLEGHDR---GVNWASFHPTLPLIVS 312 + + N G DA + + HD G+ +F + L+ + Sbjct: 228 DINAVAFFPSGNAFATGSDDATCRLFDIRADQELAMYSHDNIICGITSVAFSKSGRLLFA 287 Query: 313 GADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCV 411 G DD +W + + L GH N VSC+ Sbjct: 288 GYDDFNCNVW--DSMRQERAGVLAGHDNRVSCL 318
>GBB1_CAEBR (Q61ZF6) Guanine nucleotide-binding protein beta subunit 1| Length = 340 Score = 41.2 bits (95), Expect = 0.001 Identities = 36/153 (23%), Positives = 60/153 (39%), Gaps = 17/153 (11%) Frame = +1 Query: 4 IWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI-GALRKKTV----S 168 +W+ ++ TGH VM S P +S + D + ++WDI + K+T S Sbjct: 168 LWDIETGQQCTAFTGHTGDVMSLSLSPDFRTFISGACDASAKLWDIRDGMCKQTFPGHES 227 Query: 169 PADDIMRLTQMNTDLFGGVDAVVK---------YVLEGHDR---GVNWASFHPTLPLIVS 312 + + N G DA + + HD G+ +F + L+ + Sbjct: 228 DINAVAFFPSGNAFATGSDDATCRLFDIRADQELAMYSHDNIICGITSVAFSKSGRLLFA 287 Query: 313 GADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCV 411 G DD +W + + L GH N VSC+ Sbjct: 288 GYDDFNCNVW--DSMRQERAGVLAGHDNRVSCL 318
>GBB5_RAT (P62882) Guanine nucleotide-binding protein beta subunit 5| (Transducin beta chain 5) (Gbeta5) Length = 353 Score = 41.2 bits (95), Expect = 0.001 Identities = 37/151 (24%), Positives = 58/151 (38%) Frame = +1 Query: 4 IWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDI 183 +W+ +S CV H V ++P D S S D T R++D+ A R+ + + I Sbjct: 223 VWDMRSGQCVQAFETHESDVNSVRYYPSGDAFASGSDDATCRLYDLRADREVAIYSKESI 282 Query: 184 MRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKA 363 +FG + V + L G L+ +G +D + +W + K Sbjct: 283 ---------IFGA--SSVDFSLSGR--------------LLFAGYNDYTINVWDV--LKG 315 Query: 364 WEVDTLRGHMNNVSCVMFHAKQDIIVSNSED 456 V L GH N VS + S S D Sbjct: 316 SRVSILFGHENRVSTLRVSPDGTAFCSGSWD 346 Score = 32.0 bits (71), Expect = 0.88 Identities = 27/115 (23%), Positives = 41/115 (35%), Gaps = 2/115 (1%) Frame = +1 Query: 4 IWNWQSRTCVAVLTGHNHYVMCASFHPKE--DLVVSASLDQTVRVWDIGALRKKTVSPAD 177 +W+ +S + GH V+C P E + VS D+ VWD Sbjct: 179 LWDVESGQLLQSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVWD------------- 225 Query: 178 DIMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLW 342 MR Q E H+ VN ++P+ SG+DD +L+ Sbjct: 226 --MRSGQ------------CVQAFETHESDVNSVRYYPSGDAFASGSDDATCRLY 266 Score = 29.6 bits (65), Expect = 4.4 Identities = 14/44 (31%), Positives = 21/44 (47%) Frame = +1 Query: 4 IWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVW 135 +W+ + V++L GH + V P S S D T+RVW Sbjct: 309 VWDVLKGSRVSILFGHENRVSTLRVSPDGTAFCSGSWDHTLRVW 352 Score = 28.5 bits (62), Expect = 9.7 Identities = 13/33 (39%), Positives = 19/33 (57%) Frame = +1 Query: 40 LTGHNHYVMCASFHPKEDLVVSASLDQTVRVWD 138 L GH + V+C + + +VS+S D V VWD Sbjct: 59 LKGHGNKVLCMDWCKDKRRIVSSSQDGKVIVWD 91
>UTP15_XENLA (Q7ZXZ2) U3 small nucleolar RNA-associated protein 15 homolog| Length = 515 Score = 41.2 bits (95), Expect = 0.001 Identities = 43/169 (25%), Positives = 74/169 (43%), Gaps = 16/169 (9%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDI-GALRKKTVSPAD 177 ++++ + + +GH+ V F + +VS S D T ++WDI + + Sbjct: 105 QLFDISGKAALRQFSGHSKAVHFVDFTSDKYRIVSGSDDYTSKLWDIPNGIEIASYKEHT 164 Query: 178 DIMR---LTQMNTDLF--GGVDAVVKYVLEG----------HDRGVNWASFHPTLPLIVS 312 D +R + +N DLF G D +K V +G H + V P+ L+VS Sbjct: 165 DYIRCGCTSSLNNDLFATGSYDHTIK-VFDGRTDKSVMSMDHGQPVESVLLFPSGGLLVS 223 Query: 313 GADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSEDK 459 A R VK+W + V +LR H V+C+ + ++S S D+ Sbjct: 224 -AGGRYVKVWDILKGGQLLV-SLRNHHKTVTCLCLSSSGQRLLSGSLDR 270
>WDR26_MOUSE (Q8C6G8) WD-repeat protein 26| Length = 514 Score = 41.2 bits (95), Expect = 0.001 Identities = 20/45 (44%), Positives = 29/45 (64%), Gaps = 1/45 (2%) Frame = +1 Query: 4 IWNWQSRTCVAVLTGHNHYVMCASFHPK-EDLVVSASLDQTVRVW 135 IW+ +S +A LTGH V C S++P+ ++ SAS D TVR+W Sbjct: 450 IWHKRSELPIAELTGHTRTVNCVSWNPQIPSMMASASDDGTVRIW 494 Score = 31.6 bits (70), Expect = 1.2 Identities = 34/149 (22%), Positives = 56/149 (37%), Gaps = 3/149 (2%) Frame = +1 Query: 37 VLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDIMRLTQMNTDLF 216 +LT H + V F + + S D TV +W V P +++L + Sbjct: 203 ILTEHCNEVWFCKFSNDGTKLATGSKDTTVIIWQ--------VDPDTHLLKLLK------ 248 Query: 217 GGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVDTLRGHMN 396 LEGH GV++ ++ P +V+ D +LW W V T Sbjct: 249 ---------TLEGHAYGVSYIAWSPDDSYLVACGPDDCSELW------LWNVQT-----G 288 Query: 397 NVSCVMFHAKQDIIVS---NSEDKAFASG 474 + M + +D + S N + K F +G Sbjct: 289 ELRTKMSQSHEDSLTSVAWNPDGKRFVTG 317
>WDR26_HUMAN (Q9H7D7) WD-repeat protein 26| Length = 514 Score = 41.2 bits (95), Expect = 0.001 Identities = 20/45 (44%), Positives = 29/45 (64%), Gaps = 1/45 (2%) Frame = +1 Query: 4 IWNWQSRTCVAVLTGHNHYVMCASFHPK-EDLVVSASLDQTVRVW 135 IW+ +S +A LTGH V C S++P+ ++ SAS D TVR+W Sbjct: 450 IWHKRSELPIAELTGHTRTVNCVSWNPQIPSMMASASDDGTVRIW 494 Score = 31.2 bits (69), Expect = 1.5 Identities = 34/149 (22%), Positives = 56/149 (37%), Gaps = 3/149 (2%) Frame = +1 Query: 37 VLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDIMRLTQMNTDLF 216 +LT H + V F + + S D TV +W V P +++L + Sbjct: 203 ILTEHCNEVWFCKFSNDGTKLATGSKDTTVIIWQ--------VDPDTHLLKLLK------ 248 Query: 217 GGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVDTLRGHMN 396 LEGH GV++ ++ P +V+ D +LW W V T Sbjct: 249 ---------TLEGHAYGVSYIAWSPDDNYLVACGPDDCSELW------LWNVQT-----G 288 Query: 397 NVSCVMFHAKQDIIVS---NSEDKAFASG 474 + M + +D + S N + K F +G Sbjct: 289 ELRTKMSQSHEDSLTSVAWNPDGKRFVTG 317
>TB1RB_XENLA (Q6GPC6) F-box-like/WD-repeat-containing protein TBL1XR1-B| (Transducin beta-like 1X-related homolog 1-B) (Nuclear receptor corepressor/HDAC3 complex subunit TBLR1-B) (TBL1-related protein 1-B) Length = 522 Score = 41.2 bits (95), Expect = 0.001 Identities = 34/131 (25%), Positives = 56/131 (42%), Gaps = 15/131 (11%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTV----- 165 RIW + + L H + ++ K + ++SA +D+T +WD K Sbjct: 258 RIWT-KDGNLASTLGQHKGPIFALKWNKKGNFILSAGVDKTTIIWDAHTGEAKQQFPFHS 316 Query: 166 SPADDI-----MRLTQMNTDLFG-----GVDAVVKYVLEGHDRGVNWASFHPTLPLIVSG 315 +PA D+ +TD+ G D +K +GH VN + PT L+ S Sbjct: 317 APALDVDWQSNNTFASCSTDMCIHVCKLGQDRPIK-TFQGHTNEVNAIKWDPTGNLLASC 375 Query: 316 ADDRQVKLWRM 348 +DD +K+W M Sbjct: 376 SDDMTLKIWSM 386 Score = 37.7 bits (86), Expect = 0.016 Identities = 32/141 (22%), Positives = 59/141 (41%) Frame = +1 Query: 37 VLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDIMRLTQMNTDLF 216 VL GH V +++P DL+ S S D T R+W++ + + +L + Sbjct: 172 VLRGHESEVFICAWNPVSDLLASGSGDSTARIWNL------SENSTSGSTQLVLRHCIRE 225 Query: 217 GGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVDTLRGHMN 396 GG D ++ V ++ L+ +G+ D ++W + A TL H Sbjct: 226 GGQDV-------PSNKDVTSLDWNSEGTLLATGSYDGFARIWTKDGNLA---STLGQHKG 275 Query: 397 NVSCVMFHAKQDIIVSNSEDK 459 + + ++ K + I+S DK Sbjct: 276 PIFALKWNKKGNFILSAGVDK 296 Score = 37.0 bits (84), Expect = 0.027 Identities = 28/123 (22%), Positives = 44/123 (35%), Gaps = 9/123 (7%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKED---------LVVSASLDQTVRVWDIGALR 153 +IW+ + TCV L HN + + P ++ SAS D TVR+WD+ Sbjct: 382 KIWSMKHDTCVHDLQAHNKEIYTIKWSPTGPGTNNPNANLMLASASFDSTVRLWDVDR-- 439 Query: 154 KKTVSPADDIMRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQV 333 + + L H V +F P + SG+ D+ V Sbjct: 440 -------------------------GICIHTLTKHQEPVYSVAFSPDGRYLASGSFDKCV 474 Query: 334 KLW 342 +W Sbjct: 475 HIW 477 Score = 34.3 bits (77), Expect = 0.18 Identities = 14/46 (30%), Positives = 22/46 (47%) Frame = +1 Query: 1 RIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWD 138 R+W+ C+ LT H V +F P + S S D+ V +W+ Sbjct: 433 RLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWN 478 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 83,081,697 Number of Sequences: 219361 Number of extensions: 1849173 Number of successful extensions: 8725 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 5606 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 7514 length of database: 80,573,946 effective HSP length: 103 effective length of database: 57,979,763 effective search space used: 3304846491 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
