>COPB_DROME (P45437) Coatomer subunit beta (Beta-coat protein) (Beta-COP)|
          Length = 964

 Score = 92.0 bits (227), Expect = 6e-19
 Identities = 42/95 (44%), Positives = 63/95 (66%)
 Frame = +2

Query: 170 PCTLLVHFDKGSAAMANEIKADLEGSDVAAKVEAMKRAVMLLLNGETLPTLFITVVRYVL 349
           PC  +++          ++K DLE  D   K+E +KR + LLLNGE  P L +T++R+VL
Sbjct: 6   PCYTIINSPDLEVTNEMQLKRDLEKGDTNVKIETLKRVIKLLLNGERYPGLIMTIIRFVL 65

Query: 350 PSEDHTIQKLLLLYLEIIDKRDAAGRVLPEMILIC 454
           P ++HTI+KLLL++ EI+ K  A G++L EMIL+C
Sbjct: 66  PVQNHTIKKLLLIFWEIVPKTSADGKLLQEMILVC 100

>COPB_RAT (P23514) Coatomer subunit beta (Beta-coat protein) (Beta-COP)|
          Length = 953

 Score = 92.0 bits (227), Expect = 6e-19
 Identities = 45/100 (45%), Positives = 68/100 (68%), Gaps = 1/100 (1%)
 Frame = +2

Query: 158 AMDKPCTLLVHFDKGSAAMAN-EIKADLEGSDVAAKVEAMKRAVMLLLNGETLPTLFITV 334
           A +  C  L++    S   +   +K DLE  DV +K EA+K+ ++++LNGE LP L +T+
Sbjct: 3   AAENVCYTLINVPMDSEPPSEISLKNDLEKGDVKSKTEALKKVIIMILNGEKLPGLLMTI 62

Query: 335 VRYVLPSEDHTIQKLLLLYLEIIDKRDAAGRVLPEMILIC 454
           +R+VLP +DHTI+KLLL++ EI+ K    GR+L EMIL+C
Sbjct: 63  IRFVLPLQDHTIKKLLLVFWEIVPKTTPDGRLLHEMILVC 102

>COPB_MOUSE (Q9JIF7) Coatomer subunit beta (Beta-coat protein) (Beta-COP)|
          Length = 953

 Score = 92.0 bits (227), Expect = 6e-19
 Identities = 45/100 (45%), Positives = 68/100 (68%), Gaps = 1/100 (1%)
 Frame = +2

Query: 158 AMDKPCTLLVHFDKGSAAMAN-EIKADLEGSDVAAKVEAMKRAVMLLLNGETLPTLFITV 334
           A +  C  L++    S   +   +K DLE  DV +K EA+K+ ++++LNGE LP L +T+
Sbjct: 3   AAENVCYTLINVPMDSEPPSEISLKNDLEKGDVKSKTEALKKVIIMILNGEKLPGLLMTI 62

Query: 335 VRYVLPSEDHTIQKLLLLYLEIIDKRDAAGRVLPEMILIC 454
           +R+VLP +DHTI+KLLL++ EI+ K    GR+L EMIL+C
Sbjct: 63  IRFVLPLQDHTIKKLLLVFWEIVPKTTPDGRLLHEMILVC 102

>COPB_HUMAN (P53618) Coatomer subunit beta (Beta-coat protein) (Beta-COP)|
          Length = 953

 Score = 92.0 bits (227), Expect = 6e-19
 Identities = 45/100 (45%), Positives = 68/100 (68%), Gaps = 1/100 (1%)
 Frame = +2

Query: 158 AMDKPCTLLVHFDKGSAAMAN-EIKADLEGSDVAAKVEAMKRAVMLLLNGETLPTLFITV 334
           A +  C  L++    S   +   +K DLE  DV +K EA+K+ ++++LNGE LP L +T+
Sbjct: 3   AAENVCYTLINVPMDSEPPSEISLKNDLEKGDVKSKTEALKKVIIMILNGEKLPGLLMTI 62

Query: 335 VRYVLPSEDHTIQKLLLLYLEIIDKRDAAGRVLPEMILIC 454
           +R+VLP +DHTI+KLLL++ EI+ K    GR+L EMIL+C
Sbjct: 63  IRFVLPLQDHTIKKLLLVFWEIVPKTTPDGRLLHEMILVC 102

>COPB_SCHPO (Q9UUF7) Coatomer subunit beta (Beta-coat protein) (Beta-COP)|
          Length = 940

 Score = 66.6 bits (161), Expect = 3e-11
 Identities = 33/94 (35%), Positives = 55/94 (58%)
 Frame = +2

Query: 173 CTLLVHFDKGSAAMANEIKADLEGSDVAAKVEAMKRAVMLLLNGETLPTLFITVVRYVLP 352
           C  LV  D   A   + +K  LE  +   K+ AMK  + +++NG++LP++ + V+R+V+P
Sbjct: 3   CWTLVQQDFLEAPSVDALKTSLESKNDYVKISAMKTILRVVINGDSLPSILMHVIRFVMP 62

Query: 353 SEDHTIQKLLLLYLEIIDKRDAAGRVLPEMILIC 454
           S +  ++KLL  Y E+  K +  G +  EMIL C
Sbjct: 63  SRNKELKKLLYYYWEVCPKYNNDGTMKQEMILAC 96

>COPB_YEAST (P41810) Coatomer subunit beta (Beta-coat protein) (Beta-COP)|
          Length = 973

 Score = 58.9 bits (141), Expect = 6e-09
 Identities = 29/76 (38%), Positives = 49/76 (64%)
 Frame = +2

Query: 227 KADLEGSDVAAKVEAMKRAVMLLLNGETLPTLFITVVRYVLPSEDHTIQKLLLLYLEIID 406
           KA  +GSD   K++ MK  ++ +L G  +P L + ++R+V+PS++  ++KLL  Y EI+ 
Sbjct: 30  KALEKGSD-EQKIDTMKSILVTMLEGNPMPELLMHIIRFVMPSKNKELKKLLYFYWEIVP 88

Query: 407 KRDAAGRVLPEMILIC 454
           K    G++  EMIL+C
Sbjct: 89  KLAEDGKLRHEMILVC 104

>DAB1_MACFA (Q9BGX5) Disabled homolog 1|
          Length = 555

 Score = 31.2 bits (69), Expect = 1.3
 Identities = 16/30 (53%), Positives = 18/30 (60%), Gaps = 6/30 (20%)
 Frame = +3

Query: 39  PVNHSPPLPAPRSRSTS------AADPTTD 110
           P  +SPP PAPR  S S      A+DPTTD
Sbjct: 477 PSTNSPPTPAPRQSSPSKSSASHASDPTTD 506

>DAB1_HUMAN (O75553) Disabled homolog 1|
          Length = 555

 Score = 31.2 bits (69), Expect = 1.3
 Identities = 16/30 (53%), Positives = 18/30 (60%), Gaps = 6/30 (20%)
 Frame = +3

Query: 39  PVNHSPPLPAPRSRSTS------AADPTTD 110
           P  +SPP PAPR  S S      A+DPTTD
Sbjct: 477 PSTNSPPTPAPRQSSPSKSSASHASDPTTD 506

>IRS1_MOUSE (P35569) Insulin receptor substrate 1 (IRS-1)|
          Length = 1233

 Score = 30.8 bits (68), Expect = 1.7
 Identities = 15/44 (34%), Positives = 22/44 (50%)
 Frame = +3

Query: 21  ASRLFAPVNHSPPLPAPRSRSTSAADPTTDTPHAVALRRGCTAD 152
           +SRL  P+NHS  +P P SR + +A        +     G T+D
Sbjct: 357 SSRLHPPLNHSRSIPMPSSRCSPSATSPVSLSSSSTSGHGSTSD 400

>IRS1_RAT (P35570) Insulin receptor substrate 1 (IRS-1) (pp185)|
          Length = 1235

 Score = 30.8 bits (68), Expect = 1.7
 Identities = 15/44 (34%), Positives = 22/44 (50%)
 Frame = +3

Query: 21  ASRLFAPVNHSPPLPAPRSRSTSAADPTTDTPHAVALRRGCTAD 152
           +SRL  P+NHS  +P P SR + +A        +     G T+D
Sbjct: 357 SSRLHPPLNHSRSIPMPSSRCSPSATSPVSLSSSSTSGHGSTSD 400

>IRS1A_XENLA (Q91615) Insulin receptor substrate 1-A (IRS1-A) (xIRS-1-A)|
           (XIRS-L)
          Length = 885

 Score = 29.6 bits (65), Expect = 3.8
 Identities = 14/44 (31%), Positives = 22/44 (50%)
 Frame = +3

Query: 21  ASRLFAPVNHSPPLPAPRSRSTSAADPTTDTPHAVALRRGCTAD 152
           +SRL  P+NHS  +P P +R + +A        +     G T+D
Sbjct: 155 SSRLHPPLNHSRSIPMPATRCSPSATSPVSLSSSSTSGHGSTSD 198

>MAM1_SCHPO (P78966) Mating factor M secretion protein mam1 (Multiple drug|
            resistance protein homolog) (P-glycoprotein)
          Length = 1336

 Score = 29.6 bits (65), Expect = 3.8
 Identities = 19/71 (26%), Positives = 37/71 (52%)
 Frame = +2

Query: 149  RSGAMDKPCTLLVHFDKGSAAMANEIKADLEGSDVAAKVEAMKRAVMLLLNGETLPTLFI 328
            +SG +  P    + FD  S A  +  +  L  ++V+  +EA ++  ++ ++G    TL +
Sbjct: 1087 KSGYLKFPLVGKIEFDGVSFAYPDSERNHLALNNVSLSIEAREKVAIVGISGSGKSTL-V 1145

Query: 329  TVVRYVLPSED 361
             ++R   PSED
Sbjct: 1146 ELLRKTYPSED 1156

>RSNL2_MOUSE (Q8CI96) Restin-like protein 2|
          Length = 704

 Score = 29.6 bits (65), Expect = 3.8
 Identities = 26/83 (31%), Positives = 44/83 (53%), Gaps = 5/83 (6%)
 Frame = +2

Query: 194 DKG---SAAMANEIKADLEGSDVAAKVEAMKRAVMLLLNGETLPTLFITVVRYVLPSEDH 364
           DKG   +  + + +   LE +D AA  + +K+   +LL+   LP    T  + VLP+ DH
Sbjct: 218 DKGQIPAEVVPDPVDMPLEMADAAAIAKEIKQ---MLLDAVPLPC---TSAKAVLPNSDH 271

Query: 365 TIQKLLL--LYLEIIDKRDAAGR 427
           T  + +L  L L++ D+   AG+
Sbjct: 272 TTSRAMLTSLGLKLGDRVVIAGQ 294

>IRS1B_XENLA (P84770) Insulin receptor substrate 1-B (IRS1-B) (xIRS-1-B)|
           (XIRS-L')
          Length = 1088

 Score = 29.6 bits (65), Expect = 3.8
 Identities = 14/44 (31%), Positives = 22/44 (50%)
 Frame = +3

Query: 21  ASRLFAPVNHSPPLPAPRSRSTSAADPTTDTPHAVALRRGCTAD 152
           +SRL  P+NHS  +P P +R + +A        +     G T+D
Sbjct: 358 SSRLHPPLNHSRSIPMPATRCSPSATSPVSLSSSSTSGHGSTSD 401

>IRS1_CERAE (Q28224) Insulin receptor substrate 1 (IRS-1)|
          Length = 1251

 Score = 29.6 bits (65), Expect = 3.8
 Identities = 14/44 (31%), Positives = 22/44 (50%)
 Frame = +3

Query: 21  ASRLFAPVNHSPPLPAPRSRSTSAADPTTDTPHAVALRRGCTAD 152
           ++RL  P+NHS  +P P SR + +A        +     G T+D
Sbjct: 362 SARLHPPLNHSRSIPMPASRCSPSATSPVSLSSSSTSGHGSTSD 405

>DNAE2_SYMTH (Q67N73) Error-prone DNA polymerase (EC 2.7.7.7)|
          Length = 1085

 Score = 29.6 bits (65), Expect = 3.8
 Identities = 19/58 (32%), Positives = 31/58 (53%)
 Frame = -1

Query: 226  DLIRHGGGALVEVD*QRARLVHGAGSAVHPRRRATACGVSVVGSAAEVDRDLGAGRGG 53
            DL+R  GGA+     + A ++ GA   +H  RRA    V+ +  A  + ++ GAG+ G
Sbjct: 868  DLVRRTGGAVPRGPLE-ALVLAGAFDRLHSNRRAALWQVAHLLEAERIRQERGAGQAG 924

>IRS1_HUMAN (P35568) Insulin receptor substrate 1 (IRS-1)|
          Length = 1242

 Score = 29.6 bits (65), Expect = 3.8
 Identities = 14/44 (31%), Positives = 22/44 (50%)
 Frame = +3

Query: 21  ASRLFAPVNHSPPLPAPRSRSTSAADPTTDTPHAVALRRGCTAD 152
           ++RL  P+NHS  +P P SR + +A        +     G T+D
Sbjct: 362 SARLHPPLNHSRSIPMPASRCSPSATSPVSLSSSSTSGHGSTSD 405

>GR43A_DROME (Q9V4K2) Putative gustatory receptor 43a|
          Length = 427

 Score = 28.9 bits (63), Expect = 6.4
 Identities = 20/63 (31%), Positives = 32/63 (50%)
 Frame = +2

Query: 266 EAMKRAVMLLLNGETLPTLFITVVRYVLPSEDHTIQKLLLLYLEIIDKRDAAGRVLPEMI 445
           E++ + V LL N   +  LFI V   +     H +     L+LE++ KRD  G +  +M+
Sbjct: 279 ESLGKCVHLLSNSFGIAVLFILVSCLL-----HLVATAYFLFLELLSKRD-NGYLWVQML 332

Query: 446 LIC 454
            IC
Sbjct: 333 WIC 335

>FREM2_MOUSE (Q6NVD0) FRAS1-related extracellular matrix protein 2 precursor|
           (ECM3 homolog) (NV domain-containing protein 1)
          Length = 3160

 Score = 28.9 bits (63), Expect = 6.4
 Identities = 18/54 (33%), Positives = 27/54 (50%)
 Frame = +2

Query: 290 LLLNGETLPTLFITVVRYVLPSEDHTIQKLLLLYLEIIDKRDAAGRVLPEMILI 451
           L L+  T   L +  + Y  PSED   ++L  L LEI+D   AA      M+++
Sbjct: 371 LPLSSFTQRDLRLLKIAYQPPSEDSDQERLFELELEIVDPEGAASDPFAFMVVV 424

>POTE8_HUMAN (Q6S8J7) Prostate, ovary, testis expressed protein on chromosome 8|
          Length = 498

 Score = 28.5 bits (62), Expect = 8.4
 Identities = 24/91 (26%), Positives = 42/91 (46%), Gaps = 3/91 (3%)
 Frame = +2

Query: 161 MDKPCTLLVHFDKGSAAMANEIKADLEGSDVAAKVEAMKRAVMLLLNGE--TLPTLF-IT 331
           +D+ C L V   K   A+   ++   +           + A+MLL +G    LP ++  T
Sbjct: 119 LDRQCQLHVFDSKKRTALIKAVQCQED-----------ECALMLLQHGTDPNLPDMYGNT 167

Query: 332 VVRYVLPSEDHTIQKLLLLYLEIIDKRDAAG 424
            + Y + +ED  + K LLLY   I+ ++  G
Sbjct: 168 ALHYAVYNEDKLMAKTLLLYGADIESKNKGG 198

>ANPRC_MOUSE (P70180) Atrial natriuretic peptide clearance receptor precursor|
           (ANP-C) (ANPRC) (NPR-C) (Atrial natriuretic peptide
           C-type receptor) (EF-2)
          Length = 536

 Score = 28.5 bits (62), Expect = 8.4
 Identities = 11/44 (25%), Positives = 26/44 (59%)
 Frame = +2

Query: 233 DLEGSDVAAKVEAMKRAVMLLLNGETLPTLFITVVRYVLPSEDH 364
           DL+  D+   ++  +R V++  +G+T+  + + V R+ + S D+
Sbjct: 236 DLDLDDIVRYIQGSERVVIMCASGDTIRRIMLAVHRHGMTSGDY 279

>ISPG_AQUAE (O67496) 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (EC|
           1.17.4.3) (1-hydroxy-2-methyl-2-(E)-butenyl
           4-diphosphate synthase)
          Length = 357

 Score = 28.5 bits (62), Expect = 8.4
 Identities = 12/25 (48%), Positives = 14/25 (56%)
 Frame = -1

Query: 118 CGVSVVGSAAEVDRDLGAGRGGEWL 44
           C V+ +G A E D  L  GRG  WL
Sbjct: 300 CVVNAIGEAREADIGLACGRGFAWL 324

>ANPRC_RAT (P41740) Atrial natriuretic peptide clearance receptor precursor|
           (ANP-C) (ANPRC) (NPR-C) (Atrial natriuretic peptide
           C-type receptor)
          Length = 535

 Score = 28.5 bits (62), Expect = 8.4
 Identities = 11/44 (25%), Positives = 26/44 (59%)
 Frame = +2

Query: 233 DLEGSDVAAKVEAMKRAVMLLLNGETLPTLFITVVRYVLPSEDH 364
           DL+  D+   ++  +R V++  +G+T+  + + V R+ + S D+
Sbjct: 236 DLDLDDIVRYIQGSERVVIMCASGDTIRRIMLAVHRHGMTSGDY 279


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 47,467,305
Number of Sequences: 219361
Number of extensions: 746035
Number of successful extensions: 3557
Number of sequences better than 10.0: 23
Number of HSP's better than 10.0 without gapping: 3251
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3543
length of database: 80,573,946
effective HSP length: 102
effective length of database: 58,199,124
effective search space used: 2851757076
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)