>DNM3B_HUMAN (Q9UBC3) DNA (cytosine-5)-methyltransferase 3B (EC 2.1.1.37)|
           (Dnmt3b) (DNA methyltransferase HsaIIIB) (DNA MTase
           HsaIIIB) (M.HsaIIIB)
          Length = 853

 Score = 40.8 bits (94), Expect = 0.001
 Identities = 19/46 (41%), Positives = 24/46 (52%)
 Frame = +1

Query: 139 GDMVWGKVKSHPWWPGHVYSLTLSDDPEVHRGYRHGLVLVAFFGDG 276
           GD+VWGK+K   WWP  V S   +   +   G R     V +FGDG
Sbjct: 226 GDLVWGKIKGFSWWPAMVVSWKATSKRQAMSGMR----WVQWFGDG 267

>DNM3B_MOUSE (O88509) DNA (cytosine-5)-methyltransferase 3B (EC 2.1.1.37)|
           (Dnmt3b) (DNA methyltransferase MmuIIIB) (DNA MTase
           MmuIIIB) (M.MmuIIIB)
          Length = 859

 Score = 40.4 bits (93), Expect = 0.001
 Identities = 19/46 (41%), Positives = 24/46 (52%)
 Frame = +1

Query: 139 GDMVWGKVKSHPWWPGHVYSLTLSDDPEVHRGYRHGLVLVAFFGDG 276
           GD+VWGK+K   WWP  V S   +   +   G R     V +FGDG
Sbjct: 233 GDLVWGKIKGFSWWPAMVVSWKATSKRQAMPGMR----WVQWFGDG 274

>DNM3A_MOUSE (O88508) DNA (cytosine-5)-methyltransferase 3A (EC 2.1.1.37)|
           (Dnmt3a) (DNA methyltransferase MmuIIIA) (DNA MTase
           MmuIIIA) (M.MmuIIIA)
          Length = 908

 Score = 39.7 bits (91), Expect = 0.002
 Identities = 17/46 (36%), Positives = 25/46 (54%)
 Frame = +1

Query: 139 GDMVWGKVKSHPWWPGHVYSLTLSDDPEVHRGYRHGLVLVAFFGDG 276
           G++VWGK++   WWPG + S  ++       G R     V +FGDG
Sbjct: 289 GELVWGKLRGFSWWPGRIVSWWMTGRSRAAEGTR----WVMWFGDG 330

>DNM3A_HUMAN (Q9Y6K1) DNA (cytosine-5)-methyltransferase 3A (EC 2.1.1.37)|
           (Dnmt3a) (DNA methyltransferase HsaIIIA) (DNA MTase
           HsaIIIA) (M.HsaIIIA)
          Length = 909

 Score = 39.7 bits (91), Expect = 0.002
 Identities = 17/46 (36%), Positives = 25/46 (54%)
 Frame = +1

Query: 139 GDMVWGKVKSHPWWPGHVYSLTLSDDPEVHRGYRHGLVLVAFFGDG 276
           G++VWGK++   WWPG + S  ++       G R     V +FGDG
Sbjct: 290 GELVWGKLRGFSWWPGRIVSWWMTGRSRAAEGTR----WVMWFGDG 331

>MSH6_MOUSE (P54276) DNA mismatch repair protein MSH6 (MutS-alpha 160 kDa|
           subunit) (G/T mismatch-binding protein) (GTBP) (GTMBP)
           (p160)
          Length = 1358

 Score = 36.2 bits (82), Expect = 0.022
 Identities = 17/45 (37%), Positives = 25/45 (55%)
 Frame = +1

Query: 139 GDMVWGKVKSHPWWPGHVYSLTLSDDPEVHRGYRHGLVLVAFFGD 273
           GD+VW K++ +PWWP  VY+    D   + +  +   V V FF D
Sbjct: 93  GDLVWAKMEGYPWWPCLVYNHPF-DGTFIRKKGKSVRVHVQFFDD 136

>MSH6_HUMAN (P52701) DNA mismatch repair protein MSH6 (MutS-alpha 160 kDa|
           subunit) (G/T mismatch binding protein) (GTBP) (GTMBP)
           (p160)
          Length = 1360

 Score = 35.4 bits (80), Expect = 0.038
 Identities = 11/20 (55%), Positives = 16/20 (80%)
 Frame = +1

Query: 139 GDMVWGKVKSHPWWPGHVYS 198
           GD+VW K++ +PWWP  VY+
Sbjct: 93  GDLVWAKMEGYPWWPCLVYN 112

>NSD1_HUMAN (Q96L73) Histone-lysine N-methyltransferase, H3 lysine-36 and H4|
           lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase)
           (H4-K20-HMTase) (Nuclear receptor binding SET domain
           containing protein 1) (NR-binding SET domain containing
           protein) (Androgen r
          Length = 2696

 Score = 33.1 bits (74), Expect = 0.19
 Identities = 10/20 (50%), Positives = 13/20 (65%)
 Frame = +1

Query: 139 GDMVWGKVKSHPWWPGHVYS 198
           GD++W K K  PWWP  + S
Sbjct: 324 GDLIWAKFKRRPWWPCRICS 343



 Score = 28.9 bits (63), Expect = 3.6
 Identities = 9/24 (37%), Positives = 14/24 (58%)
 Frame = +1

Query: 121  GWTPRFGDMVWGKVKSHPWWPGHV 192
            G  P + ++VW KV  + WWP  +
Sbjct: 1751 GKKPHYREIVWVKVGRYRWWPAEI 1774

>MES4_DROME (Q8MT36) Probable histone methyltransferase Mes-4 (Maternal-effect|
            sterile 4)
          Length = 1427

 Score = 32.7 bits (73), Expect = 0.25
 Identities = 14/50 (28%), Positives = 23/50 (46%)
 Frame = +1

Query: 121  GWTPRFGDMVWGKVKSHPWWPGHVYSLTLSDDPEVHRGYRHGLVLVAFFG 270
            G  P +G++VW K  +  WWP  +   T      + + +     +V FFG
Sbjct: 1044 GRLPLYGEIVWAKFNNFRWWPAIILPPTEVPSNILKKAHGENDFVVRFFG 1093



 Score = 29.6 bits (65), Expect = 2.1
 Identities = 12/22 (54%), Positives = 16/22 (72%), Gaps = 1/22 (4%)
 Frame = +1

Query: 121 GW-TPRFGDMVWGKVKSHPWWP 183
           GW T + GD+ WGKV S+ +WP
Sbjct: 389 GWPTYQVGDLFWGKVFSYCFWP 410

>ZCPW1_HUMAN (Q9H0M4) Zinc finger CW-type PWWP domain protein 1|
          Length = 494

 Score = 31.2 bits (69), Expect = 0.72
 Identities = 9/20 (45%), Positives = 13/20 (65%)
 Frame = +1

Query: 139 GDMVWGKVKSHPWWPGHVYS 198
           G ++W K   +PWWPG + S
Sbjct: 318 GSIIWAKQYGYPWWPGMIES 337

>ZCPW1_MOUSE (Q6IR42) Zinc finger CW-type PWWP domain protein 1 homolog|
          Length = 630

 Score = 30.4 bits (67), Expect = 1.2
 Identities = 8/18 (44%), Positives = 12/18 (66%)
 Frame = +1

Query: 139 GDMVWGKVKSHPWWPGHV 192
           G ++W K   +PWWPG +
Sbjct: 309 GSIIWAKQYGYPWWPGMI 326

>ATL4O_ARATH (Q8W571) RING-H2 finger protein ATL4O precursor|
          Length = 322

 Score = 29.6 bits (65), Expect = 2.1
 Identities = 15/36 (41%), Positives = 23/36 (63%)
 Frame = -3

Query: 270 SEEGDEDEAMAVAAMHLRVVGEGEAVDVARPPRMRL 163
           ++ GDED+ + +AAM   VV + E V+VA+    RL
Sbjct: 173 NKPGDEDDGVPLAAMRDHVVVDIETVEVAKSHHRRL 208

>NSD1_MOUSE (O88491) Histone-lysine N-methyltransferase, H3 lysine-36 and H4|
            lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase)
            (H4-K20-HMTase) (Nuclear receptor binding SET domain
            containing protein 1) (NR-binding SET domain containing
            protein)
          Length = 2588

 Score = 28.9 bits (63), Expect = 3.6
 Identities = 9/24 (37%), Positives = 14/24 (58%)
 Frame = +1

Query: 121  GWTPRFGDMVWGKVKSHPWWPGHV 192
            G  P + ++VW KV  + WWP  +
Sbjct: 1649 GKKPHYREIVWVKVGRYRWWPAEI 1672

>ATX1_ARATH (Q9C5X4) Histone-lysine N-methyltransferase, H3 lysine-4 specific|
           ATX1 (EC 2.1.1.43) (H3-K4-HMTase) (Trithorax-homolog
           protein 1) (TRX-homolog protein 1) (Protein SET DOMAIN
           GROUP 27)
          Length = 1062

 Score = 28.9 bits (63), Expect = 3.6
 Identities = 15/49 (30%), Positives = 24/49 (48%), Gaps = 5/49 (10%)
 Frame = +1

Query: 139 GDMVWGKVKSHPWWPGHVYSLTLSDDPEVHRGYRH-----GLVLVAFFG 270
           GD+VW K+  H  WP  +   ++  +    +G  +     G +LV FFG
Sbjct: 302 GDIVWAKLAGHAMWPAVIVDESIIGE---RKGLNNKVSGGGSLLVQFFG 347

>CKLF6_PONPY (Q5RFC1) CKLF-like MARVEL transmembrane domain-containing protein 6|
           (Chemokine-like factor superfamily member 6)
          Length = 183

 Score = 28.1 bits (61), Expect = 6.1
 Identities = 14/29 (48%), Positives = 15/29 (51%)
 Frame = +1

Query: 184 GHVYSLTLSDDPEVHRGYRHGLVLVAFFG 270
           G VYS T  +DP   RG R GL    F G
Sbjct: 4   GAVYSPTTEEDPGPARGPRSGLAAYCFLG 32

>MBD5_HUMAN (Q9P267) Methyl-CpG-binding domain protein 5 (Methyl-CpG-binding|
            protein MBD5)
          Length = 1494

 Score = 28.1 bits (61), Expect = 6.1
 Identities = 9/16 (56%), Positives = 12/16 (75%)
 Frame = +1

Query: 139  GDMVWGKVKSHPWWPG 186
            GD+VWG++K    WPG
Sbjct: 1386 GDLVWGQIKGLTSWPG 1401

>YAE1_SCHPO (Q09842) Hypothetical PWWP domain protein C23D3.01|
          Length = 407

 Score = 27.7 bits (60), Expect = 7.9
 Identities = 10/20 (50%), Positives = 12/20 (60%)
 Frame = +1

Query: 139 GDMVWGKVKSHPWWPGHVYS 198
           G+ V  K+ S PWWP  V S
Sbjct: 64  GEYVLAKMSSFPWWPARVAS 83

>TRI5_FUSPS (Q8NID7) Trichodiene synthase (EC 4.2.3.6) (Sesquiterpene cyclase)|
           (TS)
          Length = 375

 Score = 27.7 bits (60), Expect = 7.9
 Identities = 8/15 (53%), Positives = 12/15 (80%)
 Frame = +1

Query: 136 FGDMVWGKVKSHPWW 180
           FGD+  G+ ++HPWW
Sbjct: 114 FGDLQAGREQAHPWW 128

>TNSE_ECOLI (P05845) Transposon Tn7 transposition protein tnsE (Protein D)|
          Length = 538

 Score = 27.7 bits (60), Expect = 7.9
 Identities = 16/44 (36%), Positives = 19/44 (43%)
 Frame = +1

Query: 112 DSEGWTPRFGDMVWGKVKSHPWWPGHVYSLTLSDDPEVHRGYRH 243
           DSE W   F  +  G VKS   WP  ++      D   HRG  H
Sbjct: 469 DSETWRNDFEKIRRGVVKSSLNWPNSLFDQLYGQDG--HRGVNH 510

>PTN23_HUMAN (Q9H3S7) Tyrosine-protein phosphatase non-receptor type 23 (EC|
           3.1.3.48) (His-domain-containing protein tyrosine
           phosphatase) (HD-PTP) (Protein tyrosine phosphatase
           TD14) (PTP-TD14)
          Length = 1636

 Score = 27.7 bits (60), Expect = 7.9
 Identities = 14/28 (50%), Positives = 15/28 (53%)
 Frame = -3

Query: 207 EGEAVDVARPPRMRLHLAPDHVAKPRGP 124
           E EAV+   PP     L PD VA PR P
Sbjct: 732 ESEAVEAGDPPEELRSLPPDMVAGPRLP 759

>GLGA_SYNPX (Q7U7I2) Glycogen synthase (EC 2.4.1.21) (Starch [bacterial|
           glycogen] synthase)
          Length = 513

 Score = 27.7 bits (60), Expect = 7.9
 Identities = 11/29 (37%), Positives = 18/29 (62%)
 Frame = -3

Query: 207 EGEAVDVARPPRMRLHLAPDHVAKPRGPT 121
           +G+A D +RP    ++ AP+ V  P GP+
Sbjct: 472 QGQAADPSRPEDDAINAAPEAVTAPSGPS 500

>ATM_ARATH (Q9M3G7) Serine/threonine-protein kinase ATM (EC 2.7.11.1) (Ataxia|
           telangiectasia mutated homolog) (AtATM)
          Length = 3856

 Score = 27.7 bits (60), Expect = 7.9
 Identities = 9/18 (50%), Positives = 11/18 (61%)
 Frame = +1

Query: 139 GDMVWGKVKSHPWWPGHV 192
           G++VW   K   WWPG V
Sbjct: 109 GNLVWVMTKYKKWWPGEV 126


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 36,116,213
Number of Sequences: 219361
Number of extensions: 601286
Number of successful extensions: 1839
Number of sequences better than 10.0: 21
Number of HSP's better than 10.0 without gapping: 1798
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 1839
length of database: 80,573,946
effective HSP length: 68
effective length of database: 65,657,398
effective search space used: 1575777552
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)