Clone Name | bastl20e09 |
---|---|
Clone Library Name | barley_pub |
>CEP2_HUMAN (Q9BV73) Centrosomal protein 2 (Centrosomal Nek2-associated protein| 1) (C-NAP1) (Centrosome protein 250) (Centrosome-associated protein CEP250) Length = 2442 Score = 50.1 bits (118), Expect = 2e-06 Identities = 38/141 (26%), Positives = 71/141 (50%), Gaps = 7/141 (4%) Frame = +3 Query: 24 EEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKEL----- 188 E +LK Q EM + +++ + Q + L ++ E + +E + L QKEL Sbjct: 888 EMRLKEQQTEMEAIQAQREEERTQAESALCQMQLETEKERVSLLE-TLLQTQKELADASQ 946 Query: 189 --EMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSH 362 E +R++ K+ T+ I++ Q L+ AQR+L+E +H ++ ALQ E S Sbjct: 947 QLERLRQD-MKVQKLKEQETTGILQTQ-----LQEAQRELKEAARQHRDDLAALQEESSS 1000 Query: 363 IXNDRGDVERKHFSIKEQIQA 425 + D+ D++++ +K Q+ A Sbjct: 1001 LLQDKMDLQKQVEDLKSQLVA 1021 Score = 45.8 bits (107), Expect = 4e-05 Identities = 35/132 (26%), Positives = 65/132 (49%), Gaps = 4/132 (3%) Frame = +3 Query: 48 AEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIREEN----RK 215 AE AR +L+ LA+ +++ L + ++ + E + LQ +L I+EE +K Sbjct: 636 AEQARNALQVDLAEAEKRREALWEKNTHLEAQLQKAEEAGAELQADLRDIQEEKEEIQKK 695 Query: 216 LDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHIXNDRGDVERK 395 L + H + +L+ L ++ EE ++R V+EK+AL E + + VER Sbjct: 696 LSESRHQQEAATTQLEQ----LHQEAKRQEEVLARAVQEKEALVREKAALEVRLQAVERD 751 Query: 396 HFSIKEQIQAVN 431 + EQ+Q ++ Sbjct: 752 RQDLAEQLQGLS 763 Score = 35.0 bits (79), Expect = 0.079 Identities = 31/143 (21%), Positives = 71/143 (49%), Gaps = 10/143 (6%) Frame = +3 Query: 24 EEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIRE 203 E + S+++E+ + L + +A +Q +LR L++ + + ++A+K L ++E ++ Sbjct: 1305 EGKQNSLESEL--MELHETMASLQSRLRRAELQRMEAQGERELLQAAKENLTAQVEHLQA 1362 Query: 204 ---ENRK-------LDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHE 353 E R L++ ++ S + +E+ S + + L+E+ V + KALQ Sbjct: 1363 AVVEARAQASAAGILEEDLRTARSALKLKNEEVESERERAQALQEQGELKVAQGKALQEN 1422 Query: 354 LSHIXNDRGDVERKHFSIKEQIQ 422 L+ + + E + +++ QIQ Sbjct: 1423 LALLTQTLAEREEEVETLRGQIQ 1445
>NUMA1_HUMAN (Q14980) Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H| antigen) Length = 2115 Score = 48.9 bits (115), Expect = 5e-06 Identities = 33/137 (24%), Positives = 66/137 (48%), Gaps = 11/137 (8%) Frame = +3 Query: 21 QEEQLKSMQAEMARLSL-----------EKQLAQVQEKLRLLSLEKHGETSKCKDVEASK 167 ++ Q+ MQ + RL+L K+L ++++K L++ H +C+D++ K Sbjct: 247 KDAQIAMMQQRIDRLALLNEKQAASPLEPKELEELRDKNESLTMRLHETLKQCQDLKTEK 306 Query: 168 LMLQKELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQ 347 + +++ + EEN L + S + +LQD + L K +E +E++ L+ Sbjct: 307 SQMDRKINQLSEENGDLSFKLREFASHLQQLQDALNELTEEHSKATQE---WLEKQAQLE 363 Query: 348 HELSHIXNDRGDVERKH 398 ELS D+ +E K+ Sbjct: 364 KELSAALQDKKCLEEKN 380 Score = 31.6 bits (70), Expect = 0.87 Identities = 31/137 (22%), Positives = 65/137 (47%), Gaps = 3/137 (2%) Frame = +3 Query: 30 QLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIREEN 209 +L++++AE+++L E+Q + QE+ L E + + +++ LQ +LE Sbjct: 1121 KLEALRAEVSKL--EQQCQKQQEQADSLERSLEAERASRAERDSALETLQGQLE------ 1172 Query: 210 RKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHIXNDRGDVE 389 K + HS ++ L +AQR+L ++ + KA + + R + E Sbjct: 1173 EKAQELGHSQSA-----------LASAQRELAAFRTKVQDHSKAEDEWKAQVARGRQEAE 1221 Query: 390 RKH---FSIKEQIQAVN 431 RK+ S++E++ +N Sbjct: 1222 RKNSLISSLEEEVSILN 1238 Score = 28.1 bits (61), Expect = 9.7 Identities = 28/121 (23%), Positives = 52/121 (42%), Gaps = 13/121 (10%) Frame = +3 Query: 33 LKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIREENR 212 L++ Q +M RL +KQLA + L LE + +A M+Q+ ++ + N Sbjct: 209 LQTPQFQMRRL--KKQLADERSNRDELELELAENRKLLTEKDAQIAMMQQRIDRLALLNE 266 Query: 213 K-------------LDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHE 353 K L D+N S T + + LK + +++ ++++ EE L + Sbjct: 267 KQAASPLEPKELEELRDKNESLTMRLHETLKQCQDLKTEKSQMDRKINQLSEENGDLSFK 326 Query: 354 L 356 L Sbjct: 327 L 327
>MYH9_RAT (Q62812) Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle| myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A) Length = 1960 Score = 48.1 bits (113), Expect = 9e-06 Identities = 34/120 (28%), Positives = 62/120 (51%), Gaps = 4/120 (3%) Frame = +3 Query: 3 KLSVSIQEEQLKSMQAEMARLSLEKQLAQVQEKLR----LLSLEKHGETSKCKDVEASKL 170 K+ +QE Q+K + E R L +++++Q +L LL+ + KD A + Sbjct: 1248 KVEAQLQELQVKFSEGERVRTELADKVSKLQVELDSVTGLLNQSDSKSSKLTKDFSALES 1307 Query: 171 MLQKELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQH 350 LQ E+++EENR Q S ++ + +++DE S + + EEE R++E++ A H Sbjct: 1308 QLQDTQELLQEENR----QKLSLSTKLKQMEDEKNSFREQLEEEEEEAKRNLEKQIATLH 1363 Score = 44.7 bits (104), Expect = 1e-04 Identities = 33/148 (22%), Positives = 74/148 (50%), Gaps = 12/148 (8%) Frame = +3 Query: 12 VSIQEEQLKSMQAEMARLS-----LEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLML 176 V +EE+ + +QAE ++ LE+QL + + + L LEK +K K +E ++++ Sbjct: 923 VEEEEERCQYLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEDQIIM 982 Query: 177 QKELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRK-------LEEEVSRHVEEK 335 + + + +E + L+D+ T+ ++ +++ SL + K LEE + R +++ Sbjct: 983 EDQNCKLAKEKKLLEDRVAEFTTDLMEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQR 1042 Query: 336 KALQHELSHIXNDRGDVERKHFSIKEQI 419 + L+ + D D+ + ++ QI Sbjct: 1043 QELEKTRRKLEGDSTDLSDQIAELQAQI 1070 Score = 35.8 bits (81), Expect = 0.046 Identities = 38/170 (22%), Positives = 76/170 (44%), Gaps = 33/170 (19%) Frame = +3 Query: 18 IQEEQLKSMQAEMARLSLEKQLAQ------------VQEKLRLLSLEKHGETSKCKDVEA 161 ++E+Q+ M+ + +L+ EK+L + +EK + L+ K+ + D+E Sbjct: 975 LEEDQI-IMEDQNCKLAKEKKLLEDRVAEFTTDLMEEEEKSKSLAKLKNKHEAMITDLEE 1033 Query: 162 SKLMLQKELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVS---RHVEE 332 +K+ + + + RKL+ + + I LQ +I LK K EEE+ VEE Sbjct: 1034 RLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEE 1093 Query: 333 KKA-----------LQHELSHIXND-------RGDVERKHFSIKEQIQAV 428 + A L+ ++S + D R E++ + E+++A+ Sbjct: 1094 EAAQKNMALKKIRELETQISELQEDLESERACRNKAEKQKRDLGEELEAL 1143 Score = 34.7 bits (78), Expect = 0.10 Identities = 27/145 (18%), Positives = 60/145 (41%), Gaps = 8/145 (5%) Frame = +3 Query: 12 VSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELE 191 +S +E L+S +A R EKQ + E+L L E + + ++E+ Sbjct: 1112 ISELQEDLESERA--CRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVS 1169 Query: 192 MIRE--------ENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQ 347 ++++ ++ + + + L +++ K + LE+ E+ L Sbjct: 1170 ILKKTLEDEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKATLEKAKQTLENERGELA 1229 Query: 348 HELSHIXNDRGDVERKHFSIKEQIQ 422 +E+ + +GD E K ++ Q+Q Sbjct: 1230 NEVKALLQGKGDSEHKRKKVEAQLQ 1254 Score = 31.2 bits (69), Expect = 1.1 Identities = 30/138 (21%), Positives = 63/138 (45%), Gaps = 10/138 (7%) Frame = +3 Query: 27 EQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELE----M 194 EQL+ + E A+ +LEKQ+A + ++ + + + E +K LQK+LE Sbjct: 1342 EQLEEEEEE-AKRNLEKQIATLHAQVTDMKKKMEDGVGCLETAEEAKRRLQKDLEGLSQR 1400 Query: 195 IREENRKLDDQNHSSTSVIIRLQDEIISLKNAQR------KLEEEVSRHVEEKKALQHEL 356 + E+ D + T + L D ++ L + ++ K +++ + + E+K + + Sbjct: 1401 LEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSVSNLEKKQKKFDQLLAEEKTISAKY 1460 Query: 357 SHIXNDRGDVERKHFSIK 410 + DR + E + K Sbjct: 1461 AE-ERDRAEAEAREKETK 1477 Score = 30.8 bits (68), Expect = 1.5 Identities = 32/106 (30%), Positives = 53/106 (50%), Gaps = 14/106 (13%) Frame = +3 Query: 24 EEQLKSMQAEMARLSLEKQLAQVQEKLR--LLSLE---KHGETSKCKDVEASKLM--LQK 182 EEQL + E R + KQ+ + ++KL+ LL +E ++ E K + +AS + L++ Sbjct: 1820 EEQLDNETKE--RQAASKQVRRAEKKLKDVLLQVEDERRNAEQFKDQADKASTRLKQLKR 1877 Query: 183 ELEMIREE-------NRKLDDQNHSSTSVIIRLQDEIISLKNAQRK 299 +LE EE RKL + +T + E+ SLKN R+ Sbjct: 1878 QLEEAEEEAQRANASRRKLQRELEDATETADAMNREVSSLKNKLRR 1923 Score = 29.3 bits (64), Expect = 4.3 Identities = 32/138 (23%), Positives = 64/138 (46%), Gaps = 5/138 (3%) Frame = +3 Query: 24 EEQLKSMQAEMARL-----SLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKEL 188 E++LKSM+AEM +L + E+ Q Q++ L+ E + K K L+ + Sbjct: 1672 EKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEALI 1731 Query: 189 EMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHIX 368 ++ EE L+++ ++ + RL+ + + L E S H ++ + Sbjct: 1732 ALLEEE---LEEEQGNTELINDRLKKANLQIDQINTDLNLERS-HAQKNE---------- 1777 Query: 369 NDRGDVERKHFSIKEQIQ 422 N R +ER++ +K ++Q Sbjct: 1778 NARQQLERQNKELKAKLQ 1795
>MYS3_HYDAT (P39922) Myosin heavy chain, clone 203 (Fragment)| Length = 539 Score = 48.1 bits (113), Expect = 9e-06 Identities = 34/144 (23%), Positives = 68/144 (47%), Gaps = 1/144 (0%) Frame = +3 Query: 3 KLSVSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQK 182 +L ++ E+ ++E+ R LE ++ ++Q++L + K EA L+K Sbjct: 320 ELEEELENERKLRQKSELQRKELESRIEELQDQLETAGGATSAQVEVGKKREAECNRLRK 379 Query: 183 ELEMIREENRKLDDQNHSSTSVII-RLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELS 359 E+E + N + T+ I +Q+E ++K A+ KLE+E S E ++ L Sbjct: 380 EIEALNIANDAAISAIKAKTNATIAEIQEENEAMKKAKAKLEKEKSALNNELNETKNSLD 439 Query: 360 HIXNDRGDVERKHFSIKEQIQAVN 431 I + + ++ ++EQI +N Sbjct: 440 QIKKQKTNSDKNSRMLEEQINELN 463 Score = 42.4 bits (98), Expect = 5e-04 Identities = 33/141 (23%), Positives = 67/141 (47%), Gaps = 1/141 (0%) Frame = +3 Query: 3 KLSVSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQK 182 KL S+ E K E + L LE+++ + +EK+ L+ + S +E K K Sbjct: 117 KLESSLNEALEKLDGEEHSVLVLEEKIQEAEEKIDELTEKTEELQSNISRLETEKQNRDK 176 Query: 183 ELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRK-LEEEVSRHVEEKKALQHELS 359 +++ + E+ RK QDE IS NA++K ++EE+ E+ +A + + + Sbjct: 177 QIDTLNEDIRK---------------QDETISKMNAEKKHVDEELKDRTEQLQAAEDKCN 221 Query: 360 HIXNDRGDVERKHFSIKEQIQ 422 ++ + +E I++ ++ Sbjct: 222 NLNKTKNKLESSIREIEQDLK 242 Score = 29.6 bits (65), Expect = 3.3 Identities = 32/110 (29%), Positives = 50/110 (45%), Gaps = 2/110 (1%) Frame = +3 Query: 51 EMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIREENRKLDDQN 230 E A+ LE Q++Q+Q K++ L L K E L++ELE R+ +K + Q Sbjct: 294 ENAKEGLESQISQLQRKIQEL-LAKIEE-------------LEEELENERKLRQKSELQR 339 Query: 231 HSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELS--HIXND 374 S I LQD++ + A E + E L+ E+ +I ND Sbjct: 340 KELESRIEELQDQLETAGGATSAQVEVGKKREAECNRLRKEIEALNIAND 389
>MYH9_MOUSE (Q8VDD5) Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle| myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A) Length = 1959 Score = 46.6 bits (109), Expect = 3e-05 Identities = 36/120 (30%), Positives = 62/120 (51%), Gaps = 4/120 (3%) Frame = +3 Query: 3 KLSVSIQEEQLKSMQAEMARLSLEKQLAQVQEKLR----LLSLEKHGETSKCKDVEASKL 170 K+ +QE Q+K + E R L ++ ++Q +L LLS + KD A + Sbjct: 1248 KVEAQLQELQVKFSEGERVRTELADKVTKLQVELDSVTGLLSQSDSKSSKLTKDFSALES 1307 Query: 171 MLQKELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQH 350 LQ E+++EENR Q S ++ + +++DE S + Q + EEE R++E++ A H Sbjct: 1308 QLQDTQELLQEENR----QKLSLSTKLKQMEDEKNSFRE-QLEEEEEAKRNLEKQIATLH 1362 Score = 44.7 bits (104), Expect = 1e-04 Identities = 33/148 (22%), Positives = 74/148 (50%), Gaps = 12/148 (8%) Frame = +3 Query: 12 VSIQEEQLKSMQAEMARLS-----LEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLML 176 V +EE+ + +QAE ++ LE+QL + + + L LEK +K K +E ++++ Sbjct: 923 VEEEEERCQYLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEDQIIM 982 Query: 177 QKELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRK-------LEEEVSRHVEEK 335 + + + +E + L+D+ T+ ++ +++ SL + K LEE + R +++ Sbjct: 983 EDQNCKLAKEKKLLEDRVAEFTTNLMEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQR 1042 Query: 336 KALQHELSHIXNDRGDVERKHFSIKEQI 419 + L+ + D D+ + ++ QI Sbjct: 1043 QELEKTRRKLEGDSTDLSDQIAELQAQI 1070 Score = 36.6 bits (83), Expect = 0.027 Identities = 28/145 (19%), Positives = 61/145 (42%), Gaps = 8/145 (5%) Frame = +3 Query: 12 VSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELE 191 +S +E L+S +A +R EKQ + E+L L E + + ++E+ Sbjct: 1112 ISELQEDLESERA--SRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVS 1169 Query: 192 MIRE--------ENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQ 347 ++++ ++ + + + L D++ K + LE+ E+ L Sbjct: 1170 ILKKTLEDEAKTHEAQIQEMRQKHSQAVEELADQLEQTKRVKATLEKAKQTLENERGELA 1229 Query: 348 HELSHIXNDRGDVERKHFSIKEQIQ 422 +E+ + +GD E K ++ Q+Q Sbjct: 1230 NEVKALLQGKGDSEHKRKKVEAQLQ 1254 Score = 35.8 bits (81), Expect = 0.046 Identities = 38/170 (22%), Positives = 73/170 (42%), Gaps = 33/170 (19%) Frame = +3 Query: 18 IQEEQLKSMQAEMARLSLEKQLAQ------------VQEKLRLLSLEKHGETSKCKDVEA 161 ++E+Q+ M+ + +L+ EK+L + +EK + L+ K+ + D+E Sbjct: 975 LEEDQI-IMEDQNCKLAKEKKLLEDRVAEFTTNLMEEEEKSKSLAKLKNKHEAMITDLEE 1033 Query: 162 SKLMLQKELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVS---RHVEE 332 +K+ + + + RKL+ + + I LQ +I LK K EEE+ VEE Sbjct: 1034 RLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEE 1093 Query: 333 KKA------------------LQHELSHIXNDRGDVERKHFSIKEQIQAV 428 + A LQ +L R E++ + E+++A+ Sbjct: 1094 EAAQKNMALKKIRELETQISELQEDLESERASRNKAEKQKRDLGEELEAL 1143 Score = 31.2 bits (69), Expect = 1.1 Identities = 36/120 (30%), Positives = 59/120 (49%), Gaps = 16/120 (13%) Frame = +3 Query: 24 EEQLKSMQAEMARLSLEKQLAQVQEKLR--LLSLE---KHGETSKCKDVEASKLM--LQK 182 EEQL + E R + KQ+ + ++KL+ LL +E ++ E K + +AS + L++ Sbjct: 1819 EEQLDNETKE--RQAASKQVRRTEKKLKDVLLQVEDERRNAEQFKDQADKASTRLKQLKR 1876 Query: 183 ELEMIREE-------NRKLDDQNHSSTSVIIRLQDEIISLKNAQRK--LEEEVSRHVEEK 335 +LE EE RKL + +T + E+ SLKN R+ L V+R + K Sbjct: 1877 QLEEAEEEAQRANASRRKLQRELEDATETADAMNREVSSLKNKLRRGDLPFVVTRRIVRK 1936 Score = 30.8 bits (68), Expect = 1.5 Identities = 30/138 (21%), Positives = 63/138 (45%), Gaps = 10/138 (7%) Frame = +3 Query: 27 EQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELE----M 194 EQL+ + E A+ +LEKQ+A + ++ + + + E +K LQK+LE Sbjct: 1342 EQLE--EEEEAKRNLEKQIATLHAQVTDMKKKMEDGVGCLETAEEAKRRLQKDLEGLSQR 1399 Query: 195 IREENRKLDDQNHSSTSVIIRLQDEIISLKNAQR------KLEEEVSRHVEEKKALQHEL 356 + E+ D + T + L D ++ L + ++ K +++ + + E+K + + Sbjct: 1400 LEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSVSNLEKKQKKFDQLLAEEKTISAKY 1459 Query: 357 SHIXNDRGDVERKHFSIK 410 + DR + E + K Sbjct: 1460 AE-ERDRAEAEAREKETK 1476 Score = 30.4 bits (67), Expect = 1.9 Identities = 32/138 (23%), Positives = 64/138 (46%), Gaps = 5/138 (3%) Frame = +3 Query: 24 EEQLKSMQAEMARL-----SLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKEL 188 E++LKSM+AEM +L + E+ Q Q++ L+ E + K K L+ + Sbjct: 1671 EKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARI 1730 Query: 189 EMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHIX 368 ++ EE L+++ ++ + RL+ + + L E S H ++ + Sbjct: 1731 ALLEEE---LEEEQGNTELINDRLKKANLQIDQINTDLNLERS-HAQKNE---------- 1776 Query: 369 NDRGDVERKHFSIKEQIQ 422 N R +ER++ +K ++Q Sbjct: 1777 NARQQLERQNKELKAKLQ 1794
>MYH9_CHICK (P14105) Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle| myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A) Length = 1959 Score = 45.8 bits (107), Expect = 4e-05 Identities = 34/148 (22%), Positives = 72/148 (48%), Gaps = 12/148 (8%) Frame = +3 Query: 12 VSIQEEQLKSMQAEMARLS-----LEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLML 176 V +EE+ + +QAE ++ LE+QL + + + L LEK +K K +E ++L Sbjct: 924 VEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEDVIVL 983 Query: 177 QKELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRK-------LEEEVSRHVEEK 335 + + + +E + L+D+ T+ + +++ SL + K LEE + R +++ Sbjct: 984 EDQNLKLAKEKKLLEDRMSEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQR 1043 Query: 336 KALQHELSHIXNDRGDVERKHFSIKEQI 419 + L+ + D D+ + ++ QI Sbjct: 1044 QELEKTRRKLEGDSSDLHDQIAELQAQI 1071 Score = 36.2 bits (82), Expect = 0.035 Identities = 34/161 (21%), Positives = 74/161 (45%), Gaps = 21/161 (13%) Frame = +3 Query: 3 KLSVSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLL-SLEKHGETSKCKDVEASKLMLQ 179 +++ + E+ + + E AR +E+Q +++ KL+ + S K + +EA + L+ Sbjct: 1761 QMNADLNAERSNAQKNENARQQMERQNKELKLKLQEMESAVKSKYKATITALEAKIVQLE 1820 Query: 180 KELEM-----------IREENRKL-------DDQNHSSTSVIIRLQDEIISLKNAQRKLE 305 ++L+M +R +KL DD+ ++ + + LK +R+LE Sbjct: 1821 EQLDMETKERQAASKQVRRAEKKLKDILLQVDDERRNAEQFKDQADKANMRLKQLKRQLE 1880 Query: 306 --EEVSRHVEEKKALQHELSHIXNDRGDVERKHFSIKEQIQ 422 EE ++ ++ LQ EL + R+ S+K +++ Sbjct: 1881 EAEEEAQRANVRRKLQRELDDATETADAMNREVSSLKSKLR 1921 Score = 35.4 bits (80), Expect = 0.061 Identities = 31/141 (21%), Positives = 62/141 (43%), Gaps = 8/141 (5%) Frame = +3 Query: 24 EEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHG---ETSKCKDVEASK----LMLQK 182 +E L+S +A +R EKQ + E+L L E T+ +++ + + +L+K Sbjct: 1117 QEDLESERA--SRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVTVLKK 1174 Query: 183 ELE-MIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELS 359 LE + ++ + + I L +++ K + LE+ E+ L +E+ Sbjct: 1175 TLEDEAKTHEAQIQEMRQKHSQAIEELAEQLEQTKRVKANLEKAKQALESERAELSNEVK 1234 Query: 360 HIXNDRGDVERKHFSIKEQIQ 422 + +GD E K + Q+Q Sbjct: 1235 VLLQGKGDAEHKRKKVDAQLQ 1255 Score = 34.3 bits (77), Expect = 0.13 Identities = 32/137 (23%), Positives = 57/137 (41%), Gaps = 21/137 (15%) Frame = +3 Query: 81 LAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIREENRKLDDQNHSSTSVIIRL 260 L + +EK + L+ K+ + D+E +K+ + + + RKL+ + I L Sbjct: 1008 LTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSSDLHDQIAEL 1067 Query: 261 QDEIISLKNAQRKLEEEVS---RHVEEKKA------------------LQHELSHIXNDR 377 Q +I LK K EEE+ VEE+ A LQ +L R Sbjct: 1068 QAQIAELKIQLSKKEEELQAALARVEEEAAQKNMALKKIRELESQITELQEDLESERASR 1127 Query: 378 GDVERKHFSIKEQIQAV 428 E++ + E+++A+ Sbjct: 1128 NKAEKQKRDLGEELEAL 1144 Score = 29.6 bits (65), Expect = 3.3 Identities = 28/134 (20%), Positives = 60/134 (44%), Gaps = 1/134 (0%) Frame = +3 Query: 24 EEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIRE 203 E++LKSM+AEM + L+++LA + R E+ + + + +E + Sbjct: 1672 EKKLKSMEAEM--IQLQEELAAAERAKRQAQQERDELADEIANSSGKGALAMEEKRRLEA 1729 Query: 204 ENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEE-EVSRHVEEKKALQHELSHIXNDRG 380 +L+++ + D LK A ++++ + E A ++E N R Sbjct: 1730 RIAQLEEELEEEQGNTEIINDR---LKKANLQIDQMNADLNAERSNAQKNE-----NARQ 1781 Query: 381 DVERKHFSIKEQIQ 422 +ER++ +K ++Q Sbjct: 1782 QMERQNKELKLKLQ 1795
>PUMA_PARUN (O61308) 227 kDa spindle- and centromere-associated protein (PUMA1)| Length = 1955 Score = 45.1 bits (105), Expect = 8e-05 Identities = 35/134 (26%), Positives = 63/134 (47%) Frame = +3 Query: 30 QLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIREEN 209 QL Q+++A S KQ Q++ +L + E D + LQ++L+ E Sbjct: 1550 QLGVAQSDLANASGRKQ--QLEGELAAVRAELRDHKQHLHDAISRIAELQRQLQDANAEK 1607 Query: 210 RKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHIXNDRGDVE 389 +L D+ II L+ I +L+N + +L ++S +E+KAL EL + +E Sbjct: 1608 SRLTDR-------IIGLEKTIGTLRNTETELRAQLSTAADERKALNSELEEMRRRIVQME 1660 Query: 390 RKHFSIKEQIQAVN 431 + + Q++ VN Sbjct: 1661 SEKKDVDNQLEEVN 1674 Score = 37.7 bits (86), Expect = 0.012 Identities = 42/180 (23%), Positives = 70/180 (38%), Gaps = 42/180 (23%) Frame = +3 Query: 3 KLSVSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKC----KDVEASKL 170 +L +I+E L + + SL ++LA V KL + ++ + C +DVE +L Sbjct: 610 QLEANIKEINLMRDEISKEKDSLAQKLADVTHKLEIETVRREDIQRSCVGHSEDVEKQRL 669 Query: 171 ML---QKELEMIREENRKLDDQNHSSTSVIIRLQDEIIS--------------------- 278 + ++E+ +R N +LD + + + L++ IIS Sbjct: 670 QIIEYEREVMALRRLNDELDTNVKTGQAKVTSLENSIISVQTEVTKLTTLNDKLQKEKQS 729 Query: 279 --------------LKNAQRKLEEEVSRHVEEKKALQHELSHIXNDRGDVERKHFSIKEQ 416 LK RKLE+E + EE KAL HE I E + E+ Sbjct: 730 IMSSKQKADTDVDLLKEKLRKLEQECDKLKEENKAL-HEDEQIARQMCKEEASRIHLLER 788 Score = 35.8 bits (81), Expect = 0.046 Identities = 23/122 (18%), Positives = 61/122 (50%), Gaps = 2/122 (1%) Frame = +3 Query: 24 EEQLKSMQAEMA--RLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMI 197 E +L++ + A R +L +L +++ ++ + EK ++ ++V +++++ K++E+ Sbjct: 1628 ETELRAQLSTAADERKALNSELEEMRRRIVQMESEKKDVDNQLEEVNKARIIMTKKIEI- 1686 Query: 198 REENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHIXNDR 377 L+ + HS+ VI + +++ + LE E + LQ +++ + D Sbjct: 1687 ------LETEKHSAELVISETASQREAIERSLNALERENKELYKNCAQLQQQIAQLEMDN 1740 Query: 378 GD 383 G+ Sbjct: 1741 GE 1742 Score = 30.8 bits (68), Expect = 1.5 Identities = 23/140 (16%), Positives = 64/140 (45%) Frame = +3 Query: 3 KLSVSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQK 182 +L +S +E LKS + ++ + E++ ++ + LE + ++ + + +Q Sbjct: 1378 ELKLSSMKEMLKSQEEKLKQRDEERR--NLKSNIVTFELEARAKDAQIRHLNDLLKRVQA 1435 Query: 183 ELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSH 362 ELE + +NR L ++ + I L+ + + +++ ++ E+++L L Sbjct: 1436 ELENSQNDNRALRERQEQYETNRIHLEQR-LPTDEGEPRVKALMAAFATERQSLSDSLKK 1494 Query: 363 IXNDRGDVERKHFSIKEQIQ 422 + + E K+ +++ + Sbjct: 1495 LASQLQISETKNADLRDDAE 1514
>MYH9_HUMAN (P35579) Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle| myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A) Length = 1959 Score = 45.1 bits (105), Expect = 8e-05 Identities = 34/148 (22%), Positives = 73/148 (49%), Gaps = 12/148 (8%) Frame = +3 Query: 12 VSIQEEQLKSMQAEMARLS-----LEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLML 176 V +EE+ + +QAE ++ LE+QL + + + L LEK +K K +E +++L Sbjct: 923 VEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIIL 982 Query: 177 QKELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRK-------LEEEVSRHVEEK 335 + + + +E + L+D+ T+ + +++ SL + K LEE + R +++ Sbjct: 983 EDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQR 1042 Query: 336 KALQHELSHIXNDRGDVERKHFSIKEQI 419 + L+ + D D+ + ++ QI Sbjct: 1043 QELEKTRRKLEGDSTDLSDQIAELQAQI 1070 Score = 43.9 bits (102), Expect = 2e-04 Identities = 35/120 (29%), Positives = 61/120 (50%), Gaps = 4/120 (3%) Frame = +3 Query: 3 KLSVSIQEEQLKSMQAEMARLSLEKQLAQVQEKLR----LLSLEKHGETSKCKDVEASKL 170 K+ +QE Q+K + E R L ++ ++Q +L LLS + KD A + Sbjct: 1248 KVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALES 1307 Query: 171 MLQKELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQH 350 LQ E+++EENR Q S ++ + +++DE S + Q + EEE ++E++ A H Sbjct: 1308 QLQDTQELLQEENR----QKLSLSTKLKQVEDEKNSFRE-QLEEEEEAKHNLEKQIATLH 1362 Score = 36.6 bits (83), Expect = 0.027 Identities = 38/170 (22%), Positives = 76/170 (44%), Gaps = 33/170 (19%) Frame = +3 Query: 18 IQEEQLKSMQAEMARLSLEKQL------------AQVQEKLRLLSLEKHGETSKCKDVEA 161 ++EEQ+ ++ + +L+ EK+L + +EK + L+ K+ + D+E Sbjct: 975 LEEEQI-ILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEE 1033 Query: 162 SKLMLQKELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVS---RHVEE 332 +K+ + + + RKL+ + + I LQ +I LK K EEE+ VEE Sbjct: 1034 RLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEE 1093 Query: 333 KKA-----------LQHELSHIXND-------RGDVERKHFSIKEQIQAV 428 + A L+ ++S + D R E++ + E+++A+ Sbjct: 1094 EAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEAL 1143 Score = 35.8 bits (81), Expect = 0.046 Identities = 30/145 (20%), Positives = 62/145 (42%), Gaps = 8/145 (5%) Frame = +3 Query: 12 VSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELE 191 +S +E L+S +A +R EKQ + E+L L E + + ++E+ Sbjct: 1112 ISELQEDLESERA--SRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVN 1169 Query: 192 MIR---EENRK-----LDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQ 347 +++ EE K + + + + L +++ K + LE+ E+ L Sbjct: 1170 ILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELA 1229 Query: 348 HELSHIXNDRGDVERKHFSIKEQIQ 422 +E+ + +GD E K ++ Q+Q Sbjct: 1230 NEVKVLLQGKGDSEHKRKKVEAQLQ 1254 Score = 30.0 bits (66), Expect = 2.5 Identities = 29/138 (21%), Positives = 63/138 (45%), Gaps = 10/138 (7%) Frame = +3 Query: 27 EQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIREE 206 EQL+ + E A+ +LEKQ+A + ++ + + + E K LQK+LE + + Sbjct: 1342 EQLE--EEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQR 1399 Query: 207 NRK----LDDQNHSSTSVIIRLQDEIISLKNAQR------KLEEEVSRHVEEKKALQHEL 356 + + D + T + L D ++ L + ++ K +++ + + E+K + + Sbjct: 1400 HEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKY 1459 Query: 357 SHIXNDRGDVERKHFSIK 410 + DR + E + K Sbjct: 1460 AE-ERDRAEAEAREKETK 1476 Score = 29.6 bits (65), Expect = 3.3 Identities = 28/134 (20%), Positives = 61/134 (45%), Gaps = 1/134 (0%) Frame = +3 Query: 24 EEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIRE 203 E++LKSM+AEM + L+++LA + R E+ + + + +E + Sbjct: 1671 EKKLKSMEAEM--IQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEA 1728 Query: 204 ENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEE-EVSRHVEEKKALQHELSHIXNDRG 380 +L+++ + D LK A ++++ ++E A ++E N R Sbjct: 1729 RIAQLEEELEEEQGNTELINDR---LKKANLQIDQINTDLNLERSHAQKNE-----NARQ 1780 Query: 381 DVERKHFSIKEQIQ 422 +ER++ +K ++Q Sbjct: 1781 QLERQNKELKVKLQ 1794 Score = 28.5 bits (62), Expect = 7.4 Identities = 29/106 (27%), Positives = 50/106 (47%), Gaps = 14/106 (13%) Frame = +3 Query: 24 EEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCK------DVEASKL-MLQK 182 EEQL + E R + KQ+ + ++KL+ + L+ E + D +++L L++ Sbjct: 1819 EEQLDNETKE--RQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKR 1876 Query: 183 ELEMIREE-------NRKLDDQNHSSTSVIIRLQDEIISLKNAQRK 299 +LE EE RKL + +T + E+ SLKN R+ Sbjct: 1877 QLEEAEEEAQRANASRRKLQRELEDATETADAMNREVSSLKNKLRR 1922
>RAD50_METTH (O26640) DNA double-strand break repair rad50 ATPase| Length = 837 Score = 44.7 bits (104), Expect = 1e-04 Identities = 28/117 (23%), Positives = 63/117 (53%) Frame = +3 Query: 24 EEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIRE 203 E + K + +++ +E ++A+++ ++ +L EK+ S +++E+ LQ E+E +R Sbjct: 217 ESEKKQLDSDIE--GIEAEIAKLKSEMEVLQREKNRIESAEREIES----LQNEIETLRS 270 Query: 204 ENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHIXND 374 + +L ++N S R DE+ + + KL+EE++ E AL+ + + +D Sbjct: 271 SSERLMERNRSIEEEYRRSLDELQKCSDIREKLQEELNSLGERISALELKRESLMDD 327 Score = 37.7 bits (86), Expect = 0.012 Identities = 33/131 (25%), Positives = 63/131 (48%) Frame = +3 Query: 36 KSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIREENRK 215 +S E + LE L + ++ L EK S + +EA L+ E+E+++ E + Sbjct: 195 RSYDLEDKKRELEGLLGEKEK----LESEKKQLDSDIEGIEAEIAKLKSEMEVLQREKNR 250 Query: 216 LDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHIXNDRGDVERK 395 ++ S+ I LQ+EI +L+++ +L E EE + EL + R ++ + Sbjct: 251 IE----SAEREIESLQNEIETLRSSSERLMERNRSIEEEYRRSLDELQKCSDIREKLQEE 306 Query: 396 HFSIKEQIQAV 428 S+ E+I A+ Sbjct: 307 LNSLGERISAL 317
>TRHY_SHEEP (P22793) Trichohyalin| Length = 1549 Score = 44.7 bits (104), Expect = 1e-04 Identities = 30/139 (21%), Positives = 66/139 (47%), Gaps = 4/139 (2%) Frame = +3 Query: 18 IQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKC----KDVEASKLMLQKE 185 +Q ++ + + E R LEK Q +E+++ EK + + K+++ + LQ+E Sbjct: 604 LQRQEREKRRQERERQYLEKVELQEEEQVQRQEREKRRQERERQYLEKELQRQEERLQEE 663 Query: 186 LEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHI 365 +++REE K + + LQ+E + + K +E R EK+ LQ + + Sbjct: 664 EQLLREEREKRRQERERQYLEKVELQEEEQLQREEREKRRQERERQYLEKEELQRQEERL 723 Query: 366 XNDRGDVERKHFSIKEQIQ 422 ++ ++R+ + Q++ Sbjct: 724 QREKEQLQREDREKRRQVR 742 Score = 41.6 bits (96), Expect = 8e-04 Identities = 34/137 (24%), Positives = 66/137 (48%), Gaps = 2/137 (1%) Frame = +3 Query: 18 IQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMI 197 +Q E+ + + E R LEK Q +E+L+ EK + + + +E K+ LQ+E ++ Sbjct: 520 LQREEREKRRQERERQYLEKVELQEEEQLQRQEREKRRQEREKQYLE--KVELQEEEQLQ 577 Query: 198 REENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHE--LSHIXN 371 R+E +K + + LQ+E + + K +E R EK LQ E + Sbjct: 578 RQERQKRRQEREKQYLEKVELQEEEQLQRQEREKRRQERERQYLEKVELQEEEQVQRQER 637 Query: 372 DRGDVERKHFSIKEQIQ 422 ++ ER+ +++++Q Sbjct: 638 EKRRQERERQYLEKELQ 654 Score = 39.3 bits (90), Expect = 0.004 Identities = 29/114 (25%), Positives = 53/114 (46%), Gaps = 3/114 (2%) Frame = +3 Query: 21 QEEQLKSMQAEMARLSLEKQL---AQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELE 191 +EEQL+ + E R E+Q ++QE+ +L E+ + + K+ LQ+E + Sbjct: 488 EEEQLQRQEREKRRQERERQYLEKVELQEEEQLQREEREKRRQERERQYLEKVELQEEEQ 547 Query: 192 MIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHE 353 + R+E K + + LQ+E + ++K +E + EK LQ E Sbjct: 548 LQRQEREKRRQEREKQYLEKVELQEEEQLQRQERQKRRQEREKQYLEKVELQEE 601 Score = 38.9 bits (89), Expect = 0.005 Identities = 30/114 (26%), Positives = 52/114 (45%), Gaps = 3/114 (2%) Frame = +3 Query: 21 QEEQLKSMQAEMARLSLEKQL---AQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELE 191 +EEQL+ + E R EKQ +++E+ +L E+ + + K+ LQ+E + Sbjct: 460 EEEQLQREEREKRRQEREKQYLEKVELREEEQLQRQEREKRRQERERQYLEKVELQEEEQ 519 Query: 192 MIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHE 353 + REE K + + LQ+E + + K +E + EK LQ E Sbjct: 520 LQREEREKRRQERERQYLEKVELQEEEQLQRQEREKRRQEREKQYLEKVELQEE 573 Score = 32.7 bits (73), Expect = 0.39 Identities = 29/134 (21%), Positives = 61/134 (45%) Frame = +3 Query: 21 QEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIR 200 +EE+L+ + ++ R EK+ Q +EK L +E E ++ E K ++E + + Sbjct: 424 EEERLQREEEQLQREEREKRRRQEREKQYLEKVELWEEEQLQRE-EREKRRQEREKQYLE 482 Query: 201 EENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHIXNDRG 380 + + ++Q R + E L+ + + EE++ R EK+ + E ++ Sbjct: 483 KVELREEEQLQRQEREKRRQERERQYLEKVELQEEEQLQREEREKRRQERERQYL----- 537 Query: 381 DVERKHFSIKEQIQ 422 E+ +EQ+Q Sbjct: 538 --EKVELQEEEQLQ 549 Score = 29.3 bits (64), Expect = 4.3 Identities = 33/153 (21%), Positives = 69/153 (45%), Gaps = 20/153 (13%) Frame = +3 Query: 21 QEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIR 200 +EEQL+ + + E+ L + +E+LR ++ K E +L+ + E ++ R Sbjct: 1287 REEQLRRQERDRKFREEEQLLQEREEQLRRQERDR-------KFREEEQLLKESEEQLRR 1339 Query: 201 EE-NRKLDDQNHSSTSVIIRLQDE----------IISLKNAQRKLEEEVSRH-------- 323 +E +RK ++ H ++R ++E + S + R+ E+E + Sbjct: 1340 QERDRKFHEKEH-----LLREREEQQLRRQELEGVFSQEEQLRRAEQEEEQRRQRQRDRK 1394 Query: 324 -VEEKKALQHELSHIXNDRGDVERKHFSIKEQI 419 +EE+++LQ E + +RK +EQ+ Sbjct: 1395 FLEEEQSLQREREEEKRRVQEQDRKFLEQEEQL 1427 Score = 28.5 bits (62), Expect = 7.4 Identities = 24/110 (21%), Positives = 48/110 (43%) Frame = +3 Query: 24 EEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIRE 203 EE K + E LE++ QE+ R E + K E +L+ ++E ++ R+ Sbjct: 960 EEDRKFREEEQQLRRLEREQQLRQERDRKFREELSRQERDRKFREEEQLLQEREEQLRRQ 1019 Query: 204 ENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHE 353 E D+ +++ ++E + + RK EE E ++ L+ + Sbjct: 1020 ER----DRKFREEEQLLQEREEQLRRQERDRKFREEEQLLQEREEQLRRQ 1065
>MYSP_SCHJA (Q05870) Paramyosin (Antigen Sj97)| Length = 866 Score = 44.7 bits (104), Expect = 1e-04 Identities = 32/135 (23%), Positives = 63/135 (46%) Frame = +3 Query: 21 QEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIR 200 + E+LK++ E + L ++ +Q ++ LSLE + K E+ LQ+ ++ + Sbjct: 321 ERERLKAVSLEKLKTKLTLEIKDLQSEIESLSLENGELIRRAKSAESLASELQRRVDELT 380 Query: 201 EENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHIXNDRG 380 E L QN+ S +RL+ + L + LE E + ++ K L+ L Sbjct: 381 IEVNTLTSQNNQLESENMRLKSLVNDLTDKNNALERENRQMNDQVKELKSSLRDANRRLT 440 Query: 381 DVERKHFSIKEQIQA 425 D+E +++ Q++A Sbjct: 441 DLE----ALRSQLEA 451 Score = 38.9 bits (89), Expect = 0.005 Identities = 38/146 (26%), Positives = 71/146 (48%), Gaps = 10/146 (6%) Frame = +3 Query: 3 KLSVSIQEEQLKSMQAE-MARLSLEKQLAQVQEKLRLLSLEKHGETSKCKD--VEASKLM 173 +L + I+E +K +AE A + + ++Q ++R L E GE+ +CKD +A K Sbjct: 702 QLEIEIREITVKLEEAEAFATREGRRMVQKLQARVRELEAEFDGESRRCKDALAQARKFE 761 Query: 174 LQ-KELEMIREENRKLDDQNHSSTSVIIRLQDEI----ISLKNAQRKLE--EEVSRHVEE 332 Q KEL+ E++R++ ++ LQD + + +K +R+LE EEVS+ Sbjct: 762 RQYKELQTQAEDDRRM----------VLELQDLLDKTQMKMKAYKRQLEEMEEVSQITMN 811 Query: 333 KKALQHELSHIXNDRGDVERKHFSIK 410 K + R D+ + +++ Sbjct: 812 KYRKAQQQIEEAEHRADMAERTVTVR 837 Score = 31.2 bits (69), Expect = 1.1 Identities = 33/146 (22%), Positives = 63/146 (43%), Gaps = 13/146 (8%) Frame = +3 Query: 24 EEQLKSMQAEMARLS-----LEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKEL 188 E +L+ + +++ RL L++QL ++ L+ E +D EA L K Sbjct: 162 ESKLEGLDSQLNRLKTLTDDLQRQLTELNNAKSRLTSENFELLHINQDYEAQILNYSKAK 221 Query: 189 EMIREE----NRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHEL 356 + + R LDD++ + ++ +L + N Q K +EE EE L++++ Sbjct: 222 SSLESQVDDLKRSLDDESRNRFNLQAQLTSLQMDYDNLQAKYDEE----SEEASNLRNQV 277 Query: 357 SHIXND----RGDVERKHFSIKEQIQ 422 S D + ER+ S E+ + Sbjct: 278 SKFNADIAALKSKFERELMSKTEEFE 303 Score = 30.4 bits (67), Expect = 1.9 Identities = 31/148 (20%), Positives = 67/148 (45%), Gaps = 33/148 (22%) Frame = +3 Query: 30 QLKSMQAEMARLSLEKQ------------LAQVQEKLRLLSLEKHGETSKCKDVEASKLM 173 ++K +Q+E+ LSLE +++Q ++ L++E + TS+ +E+ + Sbjct: 340 EIKDLQSEIESLSLENGELIRRAKSAESLASELQRRVDELTIEVNTLTSQNNQLESENMR 399 Query: 174 LQKELE-------MIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLE--------- 305 L+ + + ENR+++DQ S + + L+ + +LE Sbjct: 400 LKSLVNDLTDKNNALERENRQMNDQVKELKSSLRDANRRLTDLEALRSQLEAERDNLASA 459 Query: 306 ----EEVSRHVEEK-KALQHELSHIXND 374 EE R +++K +A Q L+H+ ++ Sbjct: 460 LHDAEEALRDMDQKYQASQAALNHLKSE 487
>CCD41_MOUSE (Q9D5R3) Coiled-coil domain-containing protein 41| Length = 692 Score = 44.3 bits (103), Expect = 1e-04 Identities = 34/136 (25%), Positives = 70/136 (51%), Gaps = 3/136 (2%) Frame = +3 Query: 24 EEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLM--LQKELEMI 197 EE+L++ Q E Q +++ + ++++ EK E K ++ E + + LQ ++ + Sbjct: 418 EEKLRASQMAEEAARRELQSTRLKLQQQIVNTEK-AEKEKLENSELKQQISHLQIQVTSL 476 Query: 198 REENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHIXNDR 377 + L + NH ++ RL+ E +L++ K + +V + +EEK+ E H ++R Sbjct: 477 TQSENDLLNSNHMLKDMVERLKQECRNLRSQAEKAQLDVEKTLEEKQIQWLEEKHKLHER 536 Query: 378 -GDVERKHFSIKEQIQ 422 D E K+ KE++Q Sbjct: 537 ITDREEKYNQAKEKLQ 552 Score = 43.1 bits (100), Expect = 3e-04 Identities = 41/140 (29%), Positives = 62/140 (44%), Gaps = 24/140 (17%) Frame = +3 Query: 27 EQLKSMQAEMARLSLEK----------------QLAQVQEKLRLLSLEKHGETSKCKDVE 158 ++LKS++AE+A L EK QLA++Q LR L EK + + Sbjct: 213 QKLKSLEAEVAELRAEKENSGAQVENVQRIQVRQLAEMQATLRSLEAEKQSAKLQAE--- 269 Query: 159 ASKLMLQKELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQR------KLE--EEV 314 L+KEL+ E+N L + H + I L E+ LK+A + KLE Sbjct: 270 ----RLEKELQSSNEQNTCLISKLHRADREISTLASEVKELKHANKLEITDIKLEAARAK 325 Query: 315 SRHVEEKKALQHELSHIXND 374 S E+ +Q EL + +D Sbjct: 326 SELERERNKIQSELDGLQSD 345
>TAXB1_MOUSE (Q3UKC1) Tax1-binding protein 1 homolog| Length = 814 Score = 43.9 bits (102), Expect = 2e-04 Identities = 25/111 (22%), Positives = 62/111 (55%), Gaps = 1/111 (0%) Frame = +3 Query: 24 EEQLKSMQAEMARLS-LEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIR 200 E+ LK + + ++ LEK+ AQ++E++ + E E +C+ ++A + L + + +R Sbjct: 155 EKTLKEKEELLKLIAVLEKETAQLREQVGRMERELSQEKGRCEQLQAEQKGLLEVSQSLR 214 Query: 201 EENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHE 353 EN + + +T+ + +L+++I+S+ + + E ++ ++ + QHE Sbjct: 215 VENEEFMKRYSDATAKVQQLEEDIVSVTHKAIEKETDLDSLKDKLRKAQHE 265
>TAXB1_RAT (Q66HA4) Tax1-binding protein 1 homolog (Liver regeneration-related| protein LRRG004) Length = 813 Score = 43.9 bits (102), Expect = 2e-04 Identities = 28/111 (25%), Positives = 61/111 (54%), Gaps = 1/111 (0%) Frame = +3 Query: 24 EEQLKSMQAEMARLS-LEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIR 200 E+ LK + + +S LEK+ AQ++E++ + E E S+C+ ++A + L + + +R Sbjct: 155 EKTLKEKEELLKLVSVLEKETAQLREQVGRMERELSHEKSRCEQLQAEQKGLLEVSQSLR 214 Query: 201 EENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHE 353 EN + + +TS +L+++I+S+ + + E E+ ++ + Q E Sbjct: 215 VENEEFMKRYSDATSKAHQLEEDIVSVTHKAVEKETELDSLKDKLRKAQQE 265 Score = 30.0 bits (66), Expect = 2.5 Identities = 33/137 (24%), Positives = 60/137 (43%), Gaps = 18/137 (13%) Frame = +3 Query: 21 QEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKE----- 185 +E +L S++ ++ + EK+ + Q K E + K ++E +KL+ + + Sbjct: 248 KETELDSLKDKLRKAQQEKEQLECQLKTEKDEKELYKVHLKNTEIENTKLVSEIQTLKNV 307 Query: 186 -------LEMIREENRKL-----DDQN-HSSTSVIIRLQDEIISLKNAQRKLEEEVSRHV 326 + +EE KL D +N H + + +++ + LK RK EE+V Sbjct: 308 DGNKESMITHFKEEIGKLQSCLADKENLHRALLLTTSNKEDTLLLKEQLRKAEEQVQATR 367 Query: 327 EEKKALQHELSHIXNDR 377 +E L ELS N R Sbjct: 368 QELIFLAKELSDAVNVR 384
>RBCC1_HUMAN (Q8TDY2) RB1-inducible coiled-coil protein 1| Length = 1594 Score = 43.9 bits (102), Expect = 2e-04 Identities = 38/141 (26%), Positives = 69/141 (48%), Gaps = 7/141 (4%) Frame = +3 Query: 18 IQEEQLKSMQAEMARLSLEKQLAQVQ---EKLRLLSLEKHGETSKCKDVEASKLMLQKEL 188 +QE +LK R LE +LA + +++++L E S+ + E K +L++E Sbjct: 1043 LQELKLKVSDLSDTRCKLEVELALKEAETDEIKILL-----EESRAQQKETLKSLLEQET 1097 Query: 189 EMIREE----NRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHEL 356 E +R E N+K+ D N + + L+ + K+ + + E +SRH EE L+ EL Sbjct: 1098 ENLRTEISKLNQKIQDNNENYQVGLAELRTLMTIEKD--QCISELISRHEEESNILKAEL 1155 Query: 357 SHIXNDRGDVERKHFSIKEQI 419 + + + ++KEQI Sbjct: 1156 NKVTSLHNQAFEIEKNLKEQI 1176
>RBCC1_MOUSE (Q9ESK9) RB1-inducible coiled-coil protein 1 (Coiled-coil-forming| protein 1) (LaXp180 protein) Length = 1588 Score = 43.5 bits (101), Expect = 2e-04 Identities = 37/139 (26%), Positives = 66/139 (47%), Gaps = 5/139 (3%) Frame = +3 Query: 18 IQEEQLKSMQAEMARLSLEKQLAQVQ---EKLRLLSLEKHGETSKCKDVEASKLMLQKEL 188 +QE +LK R LE +LA + +++++L E S+ + E K +L++E Sbjct: 1039 LQELKLKVSDLSDMRCKLEVELALKEAETDEIKILL-----EESRTQQKEMLKSLLEQET 1093 Query: 189 EMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRK--LEEEVSRHVEEKKALQHELSH 362 E +R E KL+ + H + E+ +L ++ + E +SRH EE L+ EL + Sbjct: 1094 ENLRTEISKLNQKIHDNNESYQVGLSELRALMTIEKDQCISELISRHEEESNILKAELDN 1153 Query: 363 IXNDRGDVERKHFSIKEQI 419 + + +KEQI Sbjct: 1154 VTSLHRQAYEIEKKLKEQI 1172
>UACA_MOUSE (Q8CGB3) Uveal autoantigen with coiled-coil domains and ankyrin| repeats protein (Nucling) (Nuclear membrane-binding protein) Length = 1411 Score = 43.5 bits (101), Expect = 2e-04 Identities = 32/136 (23%), Positives = 71/136 (52%), Gaps = 4/136 (2%) Frame = +3 Query: 3 KLSVSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQK 182 K S++ EQLK R LE++ V + +LL +K+ + + ++ K L+K Sbjct: 1123 KKSLNGTIEQLKEELRSKQRC-LEREQQTVSQLQQLLENQKNSSVTLAEHLKL-KEALEK 1180 Query: 183 ELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEE----EVSRHVEEKKALQH 350 E+ +++ R+ ++++ T + +LQ E+ + K A + LE ++S++ K L+ Sbjct: 1181 EVGIMKASLREKEEESQKKTKEVSKLQTEVQTTKQALKNLETREVVDMSKYKATKNDLET 1240 Query: 351 ELSHIXNDRGDVERKH 398 ++S++ + + RK+ Sbjct: 1241 QISNLNDKLASLNRKY 1256 Score = 28.9 bits (63), Expect = 5.7 Identities = 27/110 (24%), Positives = 53/110 (48%) Frame = +3 Query: 27 EQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIREE 206 ++ +++E +L +E++ Q E L +L + + + VEA K L +E ++EE Sbjct: 1079 QKYSDVKSEREKL-VEEKAKQASEILAAQNLLQK-QPVPLEQVEALKKSLNGTIEQLKEE 1136 Query: 207 NRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHEL 356 R + +LQ + + KN+ L E H++ K+AL+ E+ Sbjct: 1137 LRSKQRCLEREQQTVSQLQQLLENQKNSSVTLAE----HLKLKEALEKEV 1182
>CL190_DROME (Q9VJE5) Restin homolog (Cytoplasmic linker protein 190)| (Microtubule-binding protein 190) (d-CLIP-190) Length = 1690 Score = 43.1 bits (100), Expect = 3e-04 Identities = 34/142 (23%), Positives = 73/142 (51%), Gaps = 7/142 (4%) Frame = +3 Query: 24 EEQLKSMQAEMARLSLEKQLAQVQEKLRLL--SLEKHGETSKCKD--VEASKLMLQKELE 191 EE+LK Q +L E Q ++ EKL + SL++ ++ K K+ V+ + +++ Sbjct: 1195 EEKLKQAQQSEQKLQQESQTSK--EKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSS 1252 Query: 192 MIREENRKLDDQN---HSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSH 362 +I +N KL++ N + TS + QD+++ + +++L+EE ++ L EL Sbjct: 1253 IIEAQNTKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAK-------LSGELQQ 1305 Query: 363 IXNDRGDVERKHFSIKEQIQAV 428 + GD++ ++E ++ + Sbjct: 1306 VQEANGDIKDSLVKVEELVKVL 1327 Score = 35.8 bits (81), Expect = 0.046 Identities = 33/132 (25%), Positives = 60/132 (45%), Gaps = 17/132 (12%) Frame = +3 Query: 12 VSIQEEQLKSMQAEMARLS---------LEKQLAQVQEKLRLLSLEKHGETSKCKDVEAS 164 ++IQ+++++S AE L +Q+A +Q +L + K K E Sbjct: 497 MTIQQKEVESRIAEQLEEEQRLRENVKYLNEQIATLQSEL----VSKDEALEKFSLSECG 552 Query: 165 KLMLQKELEMIREENRKLDDQNHS--------STSVIIRLQDEIISLKNAQRKLEEEVSR 320 L++ELE+++EEN K + + + ++RL E+ +LK LE E Sbjct: 553 IENLRRELELLKEENEKQAQEAQAEFTRKLAEKSVEVLRLSSELQNLKATSDSLESERVN 612 Query: 321 HVEEKKALQHEL 356 +E + LQ E+ Sbjct: 613 KTDECEILQTEV 624 Score = 33.9 bits (76), Expect = 0.18 Identities = 22/102 (21%), Positives = 56/102 (54%) Frame = +3 Query: 30 QLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIREEN 209 +L M+A+M L +++ ++E+L+ L+ K ++ L+++L+ ++ Sbjct: 1153 ELFEMEADMNSERLIEKVTGIKEELKETHLQLDERQKKFEE-------LEEKLKQAQQSE 1205 Query: 210 RKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEK 335 +KL ++ +S + +Q + L+++ K +EE+ +++EEK Sbjct: 1206 QKLQQESQTSKEKLTEIQQSLQELQDSV-KQKEELVQNLEEK 1246 Score = 32.3 bits (72), Expect = 0.51 Identities = 30/124 (24%), Positives = 57/124 (45%), Gaps = 12/124 (9%) Frame = +3 Query: 12 VSIQEEQLKSMQAEM-----ARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLML 176 V + EE+L++ +++ L++ L + QE L E T K + +E + L Sbjct: 1324 VKVLEEKLQAATSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQLEQANGEL 1383 Query: 177 QKEL----EMIREENRKLDDQN---HSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEK 335 ++ L ++E KLD+ N S +QD++ + +R L+EE S+ E+ Sbjct: 1384 KEALCQKENGLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQEETSKLAEQL 1443 Query: 336 KALQ 347 L+ Sbjct: 1444 SQLK 1447 Score = 31.2 bits (69), Expect = 1.1 Identities = 36/158 (22%), Positives = 68/158 (43%), Gaps = 17/158 (10%) Frame = +3 Query: 9 SVSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLE-----------KHGETSKCKDV 155 S ++ E Q KS ++ +L Q Q+K R L E K K + Sbjct: 1404 SNTVLESQKKSHN------EIQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKSL 1457 Query: 156 EASKLMLQK--ELEMIREENRKLDDQNHSSTSV----IIRLQDEIISLKNAQRKLEEEVS 317 + +L+L+K E + E +K+ D+ + SV + +LQ+ + L+ A R+ + Sbjct: 1458 QQKQLLLEKGNEFDTQLAEYQKVIDEMDDAASVKSALLEQLQNRVAELETALRQANDAQK 1517 Query: 318 RHVEEKKALQHELSHIXNDRGDVERKHFSIKEQIQAVN 431 E K L+ +L + ++ R+ S+K Q+ + Sbjct: 1518 TAYLETKELRRQLESLELEK---SREVLSLKAQMNGAS 1552 Score = 30.0 bits (66), Expect = 2.5 Identities = 28/140 (20%), Positives = 63/140 (45%) Frame = +3 Query: 3 KLSVSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQK 182 KLS +Q Q + A ++ L +V+E +++L + TS+ +A+ LQ+ Sbjct: 1298 KLSGELQ-------QVQEANGDIKDSLVKVEELVKVLEEKLQAATSQLDAQQATNKELQE 1350 Query: 183 ELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSH 362 L +E L ++ + + +++ L+ A +L+E + + K LQ +L Sbjct: 1351 LLVKSQENEGNLQGES-------LAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDE 1403 Query: 363 IXNDRGDVERKHFSIKEQIQ 422 ++ H I+++++ Sbjct: 1404 SNTVLESQKKSHNEIQDKLE 1423
>UACA_CANFA (Q9GL21) Uveal autoantigen with coiled-coil domains and ankyrin| repeats protein Length = 1415 Score = 42.7 bits (99), Expect = 4e-04 Identities = 31/136 (22%), Positives = 69/136 (50%), Gaps = 4/136 (2%) Frame = +3 Query: 24 EEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIRE 203 +E+LK+ Q EK+ V + ++L +K+ + + K +KE+ MI+ Sbjct: 1131 KEELKNKQK-----CYEKEQQTVAKLHQMLENQKNSSVPLGEHLRV-KEAFEKEVGMIKA 1184 Query: 204 ENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEE----EVSRHVEEKKALQHELSHIXN 371 R+ ++++ + T + +LQ E+ K A +KLE ++S++ K L+ ++S++ Sbjct: 1185 SLREKEEESQNKTEEVSKLQSEVQDTKQALQKLETREVVDLSKYKATKSDLETQISNLNE 1244 Query: 372 DRGDVERKHFSIKEQI 419 ++ RK+ E++ Sbjct: 1245 KLANLNRKYEEACEEV 1260 Score = 36.2 bits (82), Expect = 0.035 Identities = 26/152 (17%), Positives = 71/152 (46%), Gaps = 12/152 (7%) Frame = +3 Query: 3 KLSVSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQK 182 +L+ + E + ++ E + ++Q+ Q+++ L+ + + K K ++ L L++ Sbjct: 465 ELAHKVAECKALGLECERIKEDSDEQIKQLEDALKDVQKRMYESEGKVKQMQTHFLALKE 524 Query: 183 EL------------EMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHV 326 L E ++++ + + + +++ + +L+++I + + + + V Sbjct: 525 HLTSEAAIGNHRLMEELKDQLKDMKAKYEGASAEVGKLRNQIKQNELLVEQFRRDEGKLV 584 Query: 327 EEKKALQHELSHIXNDRGDVERKHFSIKEQIQ 422 EE K LQ ELS +R R+ ++ Q++ Sbjct: 585 EENKRLQKELSMCETERDKKGRRVAEVEGQVK 616 Score = 29.3 bits (64), Expect = 4.3 Identities = 24/112 (21%), Positives = 52/112 (46%), Gaps = 2/112 (1%) Frame = +3 Query: 18 IQEEQLKSMQAEMARLSLEKQLAQVQEKLR--LLSLEKHGETSKCKDVEASKLMLQKELE 191 ++E+ + MQ R K+ Q +KL+ + +L+K D++ ++++ + Sbjct: 1004 LKEQLSEQMQKYHVREEEAKKYKQENDKLKKEIFTLQK--------DLKDKNVLIENSHD 1055 Query: 192 MIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQ 347 M R NRK ++ N ++ + + +K + KL ++ +R E A Q Sbjct: 1056 MERALNRKAEELNKQLKDLLQKYSE----IKTEKEKLVDDNARQTSELLAAQ 1103
>LVA_DROME (Q8MSS1) Protein lava lamp| Length = 2779 Score = 42.4 bits (98), Expect = 5e-04 Identities = 40/161 (24%), Positives = 76/161 (47%), Gaps = 26/161 (16%) Frame = +3 Query: 21 QEEQLKSMQAEMARLS------------LEKQLAQVQEKLRLLSLEKHGETSKCKDVEAS 164 QE++L ++ E+A+ + L++ L Q E+L L + + E S K E S Sbjct: 240 QEQELNELRTELAKRAKLIERLELSGAELQRTLTQRNEELEQLRVVQAEEDS-LKVQENS 298 Query: 165 KLMLQKELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLE-----EEVSRHVE 329 +L Q E+ ++RE +L++ N + LQ+E+ + + QR LE E+ SR + Sbjct: 299 RL--QGEVLVLRERLAELENVNDLLETTRCELQEELTTARERQRNLELEQEQEKASRSPQ 356 Query: 330 EKKA---------LQHELSHIXNDRGDVERKHFSIKEQIQA 425 + A L +L + N D++ + +++Q+ A Sbjct: 357 SEAAHTDAQVSAELAKQLQELTNQLADLQATNEELRQQVAA 397
>YNP9_CAEEL (P34562) Hypothetical GRIP and coiled-coil domain-containing| protein T05G5.9 in chromosome III Length = 660 Score = 42.4 bits (98), Expect = 5e-04 Identities = 28/146 (19%), Positives = 68/146 (46%), Gaps = 7/146 (4%) Frame = +3 Query: 3 KLSVSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQK 182 +L+ ++Q+E++KS E S E ++ ++ ++ EK G K + E +L++ Sbjct: 188 RLTKALQDEKIKSADFEARLRSAECRIVELSDQQ---GNEKLGLARKMAESENRGRILEE 244 Query: 183 ELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQR-------KLEEEVSRHVEEKKA 341 +++++ EN KL +N ++ ++ + E K K E+E + +E+ + Sbjct: 245 AVDVLKSENEKLLAKNEEFSAKLVSSEKEFAEFKKKSHFVLEKKGKQEDETRKAIEKLEK 304 Query: 342 LQHELSHIXNDRGDVERKHFSIKEQI 419 + ++ + ++HF E + Sbjct: 305 SKVTITELEQQADQTRQEHFKTVEDL 330 Score = 40.0 bits (92), Expect = 0.002 Identities = 27/109 (24%), Positives = 52/109 (47%), Gaps = 4/109 (3%) Frame = +3 Query: 21 QEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASK----LMLQKEL 188 + E+ + + + S K + ++ E+LRL+ + K KD+E +K +LQ E Sbjct: 353 ESEKAHTTAIDELQSSSSKLIQRLDEELRLMRSSRDTAEQKIKDIEIAKEKVDHLLQNER 412 Query: 189 EMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEK 335 + EN L + S+T I L+ E+ L+N + ++H ++K Sbjct: 413 QRSENENGSLKSKLSSATKQIHSLEKELQELRNDFETRRIQSNQHQQQK 461
>CYTSA_RAT (Q2KN99) Cytospin-A| Length = 1118 Score = 42.4 bits (98), Expect = 5e-04 Identities = 37/147 (25%), Positives = 75/147 (51%), Gaps = 8/147 (5%) Frame = +3 Query: 6 LSVSIQEEQ--LKSMQAEMARLS--LEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLM 173 L+ +++E + + S Q EM RL LEK+ +V E L S+ G+ S +D+ S + Sbjct: 559 LAATLEEYKATVASDQIEMNRLKAQLEKEKQKVAE---LYSIHNSGDKSDIQDLLESVRL 615 Query: 174 LQKELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEE----KKA 341 +++ E + + +D H+ RLQD I +++ R +EE + +E+ + Sbjct: 616 DKEKAETLASSLQ--EDLAHTRNDAN-RLQDTIAKVEDEYRAFQEEAKKQIEDLNMTLEK 672 Query: 342 LQHELSHIXNDRGDVERKHFSIKEQIQ 422 L+ EL +R D++ F ++++++ Sbjct: 673 LRSELEEKETERSDMKETIFELEDEVE 699
>CCD41_RAT (Q66H89) Coiled-coil domain-containing protein 41| Length = 692 Score = 42.4 bits (98), Expect = 5e-04 Identities = 40/140 (28%), Positives = 62/140 (44%), Gaps = 24/140 (17%) Frame = +3 Query: 27 EQLKSMQAEMARLSLEK----------------QLAQVQEKLRLLSLEKHGETSKCKDVE 158 ++LKS++AE+A L EK QLA++Q LR L EK + + Sbjct: 213 QKLKSLEAEVAELRAEKENSGAQVENVQRIQVRQLAEMQATLRSLEAEKQSAKLQAE--- 269 Query: 159 ASKLMLQKELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQR------KLE--EEV 314 L+KEL+ E+N L + H + I L ++ LK+A + KLE Sbjct: 270 ----RLEKELQSSNEQNTCLISKLHKADREISTLTSQVKELKHANKLEITDVKLEAARAK 325 Query: 315 SRHVEEKKALQHELSHIXND 374 S E+ +Q EL + +D Sbjct: 326 SELERERNKIQSELDGLQSD 345 Score = 28.5 bits (62), Expect = 7.4 Identities = 27/136 (19%), Positives = 60/136 (44%), Gaps = 2/136 (1%) Frame = +3 Query: 30 QLKSMQAEMARLSLEKQLAQVQEKLRLLS--LEKHGETSKCKDVEASKLMLQKELEMIRE 203 Q + +Q E+ + EKQ+ ++EK +L ++ + ++ K+ QK+ + + E Sbjct: 507 QAEKVQLEVEKTLEEKQIQWLEEKHKLHERITDREEKYNQAKEKLQRAATAQKKRKSLHE 566 Query: 204 ENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHIXNDRGD 383 K RLQ+++ L+ + +LE E ++ + + E + + D Sbjct: 567 NKLK-------------RLQEKVEVLEAKKEELETE-NQVLNRQNVPFEEYTRLQKRLKD 612 Query: 384 VERKHFSIKEQIQAVN 431 ++R+H + I N Sbjct: 613 IQRRHNEFRSLILVPN 628
>MOEH_DROME (P46150) Moesin/ezrin/radixin homolog 1 (Ezrin-moesin-radixin 1)| (Protein D17) (Protein moesin) (dMoesin) Length = 578 Score = 42.4 bits (98), Expect = 5e-04 Identities = 26/102 (25%), Positives = 54/102 (52%), Gaps = 5/102 (4%) Frame = +3 Query: 24 EEQLKSMQAEMAR-----LSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKEL 188 E++LK MQ +M R L + + +++E+L+ L K + K+++A L++ Sbjct: 342 EDRLKQMQEDMERSQRDLLEAQDMIRRLEEQLKQLQAAKDELELRQKELQAMLQRLEEAK 401 Query: 189 EMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEV 314 M E KL+++ + + R+QDE+ + ++L++EV Sbjct: 402 NMEAVEKLKLEEEIMAKQMEVQRIQDEVNAKDEETKRLQDEV 443 Score = 39.3 bits (90), Expect = 0.004 Identities = 33/126 (26%), Positives = 59/126 (46%), Gaps = 2/126 (1%) Frame = +3 Query: 24 EEQLKSMQAEMARLSL-EKQLAQVQEKLRLLSLEKHGETSKCKDVEA-SKLMLQKELEMI 197 EEQLK +QA L L +K+L + ++L + K++EA KL L++E+ Sbjct: 370 EEQLKQLQAAKDELELRQKELQAMLQRLE-----------EAKNMEAVEKLKLEEEIMAK 418 Query: 198 REENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHIXNDR 377 + E +++ D+ ++ RLQDE+ + Q E + + QH H+ D Sbjct: 419 QMEVQRIQDEVNAKDEETKRLQDEVEDARRKQVIAAEAAAALLAASTTPQHH--HVAEDE 476 Query: 378 GDVERK 395 + E + Sbjct: 477 NENEEE 482
>EEA1_MOUSE (Q8BL66) Early endosome antigen 1| Length = 1411 Score = 42.0 bits (97), Expect = 6e-04 Identities = 29/113 (25%), Positives = 56/113 (49%), Gaps = 3/113 (2%) Frame = +3 Query: 27 EQLKSMQAEMARLSLE-KQLAQVQEKLRLLSLEKHGETSK--CKDVEASKLMLQKELEMI 197 E+L+ +++ L +E KQL Q +E+ L+ GE S+ CK +E + + Sbjct: 379 EELREVESTRQHLKVEVKQLQQQREEKEQHGLQLQGEVSQLHCKLLETER--------QL 430 Query: 198 REENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHEL 356 E + +L +Q S+ ++ + ++ L+ +LEE++ V LQH+L Sbjct: 431 GEAHGRLKEQRQLSSEKLMEKEQQVADLQLKLSRLEEQLKEKVTNSTELQHQL 483
>SMC2_HUMAN (O95347) Structural maintenance of chromosome 2-like 1 protein| (Chromosome-associated protein E) (hCAP-E) (XCAP-E homolog) Length = 1197 Score = 42.0 bits (97), Expect = 6e-04 Identities = 45/161 (27%), Positives = 80/161 (49%), Gaps = 23/161 (14%) Frame = +3 Query: 18 IQEEQLKSMQAEMARL--SLEK--QLAQ-----------VQEKLRLLSLEKHGETSKC-- 146 I+E +L++++ E+A L + EK QL Q +Q KL+ S K E Sbjct: 690 IKENELRALEEELAGLKNTAEKYRQLKQQWEMKTEEADLLQTKLQQSSYHKQQEELDALK 749 Query: 147 KDVEASKLMLQKELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLE------E 308 K +E S+ L+ E+ R+ K + + + + E LK+AQ+KL+ + Sbjct: 750 KTIEESEETLKNTKEIQRKAEEKYEVLENKMKNAEAERERE---LKDAQKKLDCAKTKAD 806 Query: 309 EVSRHVEEKKALQHELSHIXNDRGDVERKHFSIKEQIQAVN 431 S+ ++EK Q E+ I + +++R+H S K+Q++AVN Sbjct: 807 ASSKKMKEK---QQEVEAITLELEELKREHTSYKQQLEAVN 844 Score = 37.7 bits (86), Expect = 0.012 Identities = 28/104 (26%), Positives = 55/104 (52%), Gaps = 1/104 (0%) Frame = +3 Query: 57 ARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIREENRK-LDDQNH 233 A+ ++EK+ A+++E +L E K K+ +S L QK + I +R + Q Sbjct: 181 AQKTIEKKEAKLKEIKTILEEEITPTIQKLKEERSSYLEYQKVMREIEHLSRLYIAYQFL 240 Query: 234 SSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHI 365 + +R +E+ +++ KL+EE+S + ++ KAL HE+ + Sbjct: 241 LAEDTKVRSAEELKEMQDKVIKLQEELSENDKKIKALNHEIEEL 284
>MYO2_SACBA (Q876G9) Myosin-2 (Class V unconventional myosin MYO2) (Type V myosin| heavy chain MYO2) (Myosin V MYO2) Length = 1568 Score = 41.6 bits (96), Expect = 8e-04 Identities = 34/135 (25%), Positives = 67/135 (49%), Gaps = 18/135 (13%) Frame = +3 Query: 69 LEKQLAQVQEKLRLLSLEKHGETSKCKDVEAS---KLMLQKELEMIREENR-KLDDQNHS 236 LE ++ ++ + L E T + K+++ LQ+ LE +++E+ +D+Q + Sbjct: 945 LENKVIELTQNLASKVKENKEMTERIKELQVQVEESAKLQETLENMKKEHLVNIDNQKNK 1004 Query: 237 STSVIIRLQDEIIS----LKNAQRKLEEEVSRHVEEKKALQHELSHIXNDR--------- 377 + ++D + S LKNAQ +LEE V +H E K+ + +L + + Sbjct: 1005 DMELQKTIEDNLQSTEQNLKNAQLELEEMVKQHNELKEESRKQLDELDETKKALVEHQTL 1064 Query: 378 -GDVERKHFSIKEQI 419 GD++ + S+KE+I Sbjct: 1065 NGDLQNEVKSLKEEI 1079 Score = 30.0 bits (66), Expect = 2.5 Identities = 23/109 (21%), Positives = 50/109 (45%), Gaps = 6/109 (5%) Frame = +3 Query: 12 VSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETS------KCKDVEASKLM 173 + +Q E+ +Q + + E + +K + + L+K E + K+ + Sbjct: 973 LQVQVEESAKLQETLENMKKEHLVNIDNQKNKDMELQKTIEDNLQSTEQNLKNAQLELEE 1032 Query: 174 LQKELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSR 320 + K+ ++EE+RK D+ + ++ Q L+N + L+EE+SR Sbjct: 1033 MVKQHNELKEESRKQLDELDETKKALVEHQTLNGDLQNEVKSLKEEISR 1081
>SMC2_CHICK (Q90988) Structural maintenance of chromosome 2 (Chromosome scaffold| protein ScII) Length = 1189 Score = 41.6 bits (96), Expect = 8e-04 Identities = 34/131 (25%), Positives = 60/131 (45%), Gaps = 2/131 (1%) Frame = +3 Query: 24 EEQLKSMQAEMARLSLE--KQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMI 197 EE+ K+++ +M E K++ Q+KL + + K K+ + L ELE + Sbjct: 770 EEEYKALENKMKNAEAERGKEIKNAQQKLNSAKKKADDSSRKMKEKQQEVEALVLELEQL 829 Query: 198 REENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHIXNDR 377 ++E Q+ ++ Q I SLK LE E + E K ++ELS +++ Sbjct: 830 KQEQASYKQQSEAA-------QQAIASLKEQVSALEAEAVKTRESLKNAENELS---SEK 879 Query: 378 GDVERKHFSIK 410 G +E + IK Sbjct: 880 GLMEERTKDIK 890 Score = 31.6 bits (70), Expect = 0.87 Identities = 25/114 (21%), Positives = 52/114 (45%), Gaps = 8/114 (7%) Frame = +3 Query: 63 LSLEKQLAQVQEKLRLLSLEKHG---ETSKCKDVEASKLMLQKELEMIREENRKLDDQ-- 227 LS K + +++L++ + + E + K++ L+++ EM EE L + Sbjct: 675 LSKLKTMRDAEDELKIKTSQLEATEKELANLKNMAEKYQHLKQQWEMKSEEAELLQTKIQ 734 Query: 228 ---NHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHIXNDRG 380 H ++ L+ I + +K EE + EE KAL++++ + +RG Sbjct: 735 QSAYHKQQEDLLALKKTIAECEETLKKTEESQRKAEEEYKALENKMKNAEAERG 788
>OFD1_HUMAN (O75665) Oral-facial-digital syndrome 1 protein (Protein 71-7A)| Length = 1012 Score = 41.6 bits (96), Expect = 8e-04 Identities = 37/153 (24%), Positives = 74/153 (48%), Gaps = 17/153 (11%) Frame = +3 Query: 24 EEQLKSMQAEMARLSLEKQLAQV-QEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIR 200 E++L Q + + K A V +EK L + KH E + K++ A + +L K+++++R Sbjct: 239 EKELTMFQNDFEKACQAKSEALVLREKSTLERIHKHQEI-ETKEIYAQRQLLLKDMDLLR 297 Query: 201 -------------EENRKLDDQNHSSTSVIIRLQDEIISL--KNAQRKLEEEVSRH-VEE 332 E N+KL ++ H S + +R Q++ I + RKL+ E+ ++ +E Sbjct: 298 GREAELKQRVEAFELNQKLQEEKHKSITEALRRQEQNIKSFEETYDRKLKNELLKYQLEL 357 Query: 333 KKALQHELSHIXNDRGDVERKHFSIKEQIQAVN 431 K + + D + K ++E++ A+N Sbjct: 358 KDDYIIRTNRLIEDERKNKEKAVHLQEELIAIN 390
>M21_STRPY (P50468) M protein, serotype 2.1 precursor| Length = 407 Score = 41.6 bits (96), Expect = 8e-04 Identities = 38/149 (25%), Positives = 71/149 (47%), Gaps = 16/149 (10%) Frame = +3 Query: 24 EEQLKSMQAEMARLS-LEKQLAQVQEKLRLLSLEKHGETSKCKDV-EASKLMLQKELEMI 197 +++ K Q L LE+Q + EK L+K + K K + EAS+ L+++LE Sbjct: 115 DQEYKEQQERQKNLEELERQSQREVEKRYQEQLQKQQQLEKEKQISEASRKSLRRDLEAS 174 Query: 198 RE-------ENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHEL 356 R E++KL ++ S + L+ ++ + + A++ LE E + EEK+ + Sbjct: 175 RAAKKDLEAEHQKLKEEKQISEASRKSLRRDLEASRAAKKDLEAEHQKLKEEKQISEASR 234 Query: 357 SHIXND-------RGDVERKHFSIKEQIQ 422 + D + D+E +H +KE+ Q Sbjct: 235 QGLSRDLEASRAAKKDLEAEHQKLKEEKQ 263
>CYTSA_CANFA (Q2KNA0) Cytospin-A| Length = 1117 Score = 41.6 bits (96), Expect = 8e-04 Identities = 34/145 (23%), Positives = 73/145 (50%), Gaps = 6/145 (4%) Frame = +3 Query: 6 LSVSIQEEQ--LKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQ 179 L+ +++E + + S Q EM RL + + + Q+ L S+ G+ S +D+ S + + Sbjct: 558 LAATLEEYKATVASDQIEMNRLKAQLE-NEKQKVAELYSIHNSGDKSDIQDLLESVRLDK 616 Query: 180 KELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEE----KKALQ 347 ++ E + + +D H+ RLQD I +++ R +EE + +EE + L+ Sbjct: 617 EKAETLASSLQ--EDLAHTRNDAN-RLQDTIAKVEDEYRAFQEEAKKQIEELNMTLEKLR 673 Query: 348 HELSHIXNDRGDVERKHFSIKEQIQ 422 EL +R D++ F ++++++ Sbjct: 674 SELEEKETERSDMKETIFELEDEVE 698 Score = 28.5 bits (62), Expect = 7.4 Identities = 20/67 (29%), Positives = 37/67 (55%) Frame = +3 Query: 30 QLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIREEN 209 +L+ M+A+ L + + ++ EK ++ H T DVE++ L LQ++ IREE Sbjct: 205 ELRDMRAQ---LGINEDHSEGDEKSEKEAIIAHQPT----DVESTLLQLQEQNTAIREEL 257 Query: 210 RKLDDQN 230 +L ++N Sbjct: 258 NQLKNEN 264
>SMC_BACSU (P51834) Chromosome partition protein smc| Length = 1186 Score = 41.2 bits (95), Expect = 0.001 Identities = 38/126 (30%), Positives = 58/126 (46%), Gaps = 2/126 (1%) Frame = +3 Query: 3 KLSVSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQK 182 K +S QE +++QAE+ +L AQV+EK + LSL K + +++ L Sbjct: 336 KEELSKQEAVFETLQAEVKQLR-----AQVKEKQQALSLHNENVEEKIEQLKSDYFELLN 390 Query: 183 ELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRH--VEEKKALQHEL 356 IR E + LDDQ S + RL D N ++ L+E RH K A + E Sbjct: 391 SQASIRNELQLLDDQMSQSAVTLQRLAD------NNEKHLQE---RHDISARKAACETEF 441 Query: 357 SHIXND 374 + I + Sbjct: 442 ARIEQE 447 Score = 34.7 bits (78), Expect = 0.10 Identities = 24/121 (19%), Positives = 58/121 (47%) Frame = +3 Query: 15 SIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEM 194 ++ E+++K+++ + +EK+LA ++E L L++ + +++ ++ + LE+ Sbjct: 694 ALLEQEVKTLKHSIQ--DMEKKLADLRETGEGLRLKQQDVKGQLYELQVAEKNINTHLEL 751 Query: 195 IREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHIXND 374 +E L + + K +RKLEEE+S E+ K L+ ++ + Sbjct: 752 YDQEKSALSESDEER--------------KVRKRKLEEELSAVSEKMKQLEEDIDRLTKQ 797 Query: 375 R 377 + Sbjct: 798 K 798 Score = 33.1 bits (74), Expect = 0.30 Identities = 31/139 (22%), Positives = 63/139 (45%), Gaps = 12/139 (8%) Frame = +3 Query: 12 VSIQEEQLKSMQAEMARLSLEKQLAQ-----VQEKLRLLSLEKHGETSKCKDVEASKLML 176 +S E++K ++ ++ RL+ +KQ + +L L + + CK E + L Sbjct: 777 LSAVSEKMKQLEEDIDRLTKQKQTQSSTKESLSNELTELKIAAAKKEQACKGEEDNLARL 836 Query: 177 QKEL-------EMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEK 335 +KEL + +E+ L + SSTS +L++ N + K E ++ +++ Sbjct: 837 KKELTETELALKEAKEDLSFLTSEMSSSTSGEEKLEEAAKHKLNDKTKTIELIALRRDQR 896 Query: 336 KALQHELSHIXNDRGDVER 392 LQH L + +++R Sbjct: 897 IKLQHGLDTYERELKEMKR 915
>MYSN_ACACA (P05659) Myosin-2 heavy chain, non muscle (Myosin II heavy chain, non| muscle) Length = 1509 Score = 41.2 bits (95), Expect = 0.001 Identities = 35/142 (24%), Positives = 71/142 (50%), Gaps = 10/142 (7%) Frame = +3 Query: 3 KLSVSIQEEQLKSMQAEMARLSLEKQLAQVQE----------KLRLLSLEKHGETSKCKD 152 K V E++L +++ A+L EKQLA+ KL++L LE GE + D Sbjct: 862 KKQVKDLEKELAALKDANAKLDKEKQLAEEDADKLEKDLAALKLKILDLE--GEKA---D 916 Query: 153 VEASKLMLQKELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEE 332 +E +LQK++ + EE L ++ +S ++ ++ L+ + +L+ + Sbjct: 917 LEEDNALLQKKVAGLEEE---LQEETSASNDIL----EQKRKLEAEKGELKASLEEEERN 969 Query: 333 KKALQHELSHIXNDRGDVERKH 398 +KALQ + + ++R +++ K+ Sbjct: 970 RKALQEAKTKVESERNELQDKY 991 Score = 38.9 bits (89), Expect = 0.005 Identities = 31/132 (23%), Positives = 62/132 (46%), Gaps = 14/132 (10%) Frame = +3 Query: 42 MQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCK-----------DVEASKLML---Q 179 +Q E + SLE++LAQ + +L K +SK K +V++ K L + Sbjct: 1055 LQLEKTKKSLEEELAQTRAQLEEEKSGKEAASSKAKQLGQQLEDARSEVDSLKSKLSAAE 1114 Query: 180 KELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELS 359 K L+ +++NR LD+Q +V + + +L+ +LE++V+ +K A + Sbjct: 1115 KSLKTAKDQNRDLDEQLEDERTVRANVDKQKKALEAKLTELEDQVTALDGQKNAAAAQAK 1174 Query: 360 HIXNDRGDVERK 395 + + +R+ Sbjct: 1175 TLKTQVDETKRR 1186 Score = 30.8 bits (68), Expect = 1.5 Identities = 35/136 (25%), Positives = 63/136 (46%), Gaps = 6/136 (4%) Frame = +3 Query: 3 KLSVSIQEEQLKSMQAEMARLS--LEKQL----AQVQEKLRLLSLEKHGETSKCKDVEAS 164 K + + E LK+ + + R + E+Q+ AQ+ + L L EK +K K VEA+ Sbjct: 1366 KANYQRENESLKADRDSIERRNRDAERQVRDLRAQLDDALSRLDSEKR---AKEKSVEAN 1422 Query: 165 KLMLQKELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKAL 344 + + + L+ R+ L N + S L+DEI L ++L+ ++++ L Sbjct: 1423 RELKKVVLDRERQSLESLSKFNSALESDKQILEDEIGDLHEKNKQLQAKIAQ-------L 1475 Query: 345 QHELSHIXNDRGDVER 392 Q E+ + RG R Sbjct: 1476 QDEIDGTPSSRGGSTR 1491 Score = 30.4 bits (67), Expect = 1.9 Identities = 20/81 (24%), Positives = 39/81 (48%) Frame = +3 Query: 174 LQKELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHE 353 L+KEL +++ N KLD + + +L+ ++ +LK LE E + E+ LQ + Sbjct: 868 LEKELAALKDANAKLDKEKQLAEEDADKLEKDLAALKLKILDLEGEKADLEEDNALLQKK 927 Query: 354 LSHIXNDRGDVERKHFSIKEQ 416 ++ + + + I EQ Sbjct: 928 VAGLEEELQEETSASNDILEQ 948 Score = 30.0 bits (66), Expect = 2.5 Identities = 22/118 (18%), Positives = 52/118 (44%), Gaps = 4/118 (3%) Frame = +3 Query: 3 KLSVSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQK 182 KL + E +++ + + A+ + ++ ++ L ETS + + K Q+ Sbjct: 1312 KLKADLDEARIQLEEEQDAKSHADSSSRRLLAEIEELKKRVAKETSDKQKAQDQKANYQR 1371 Query: 183 ELEMIREENRKLDDQNHSSTSVI----IRLQDEIISLKNAQRKLEEEVSRHVEEKKAL 344 E E ++ + ++ +N + + +L D + L + +R E+ V + E KK + Sbjct: 1372 ENESLKADRDSIERRNRDAERQVRDLRAQLDDALSRLDSEKRAKEKSVEANRELKKVV 1429
>SPO15_SCHPO (Q10411) Sporulation-specific protein 15| Length = 1957 Score = 41.2 bits (95), Expect = 0.001 Identities = 37/141 (26%), Positives = 68/141 (48%), Gaps = 3/141 (2%) Frame = +3 Query: 3 KLSVSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHG---ETSKCKDVEASKLM 173 KL+ + +E QL AE RLSL ++ +Q +++ LS K + + +E S Sbjct: 1602 KLASTTEELQL----AENERLSLTTRMLDLQNQVKDLSNIKDSLSEDLRTLRSLEDSVAS 1657 Query: 174 LQKELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHE 353 LQKE ++ ++ + LQD + S++ +LE+EVSR V++ + Sbjct: 1658 LQKECKI--------------KSNTVESLQDVLTSVQARNAELEDEVSRSVDKIRRRDDR 1703 Query: 354 LSHIXNDRGDVERKHFSIKEQ 416 H+ G +++ H ++EQ Sbjct: 1704 CEHLS---GKLKKLHSQLEEQ 1721 Score = 37.0 bits (84), Expect = 0.021 Identities = 36/138 (26%), Positives = 68/138 (49%), Gaps = 2/138 (1%) Frame = +3 Query: 24 EEQLKSMQAEMARL--SLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMI 197 E+ +AEM SLE+ + ++++ LS S+ +D + + L+ +L+ + Sbjct: 1350 EKNFLRKEAEMTENIHSLEEGKEETKKEIAELS-------SRLEDNQLATNKLKNQLDHL 1402 Query: 198 REENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHIXNDR 377 +E R +D S+II L++ SL N ++K S ++ K L+H L Sbjct: 1403 NQEIRLKEDVLKEKESLIISLEE---SLSNQRQK----ESSLLDAKNELEHMLD------ 1449 Query: 378 GDVERKHFSIKEQIQAVN 431 D RK+ S+ E+I+++N Sbjct: 1450 -DTSRKNSSLMEKIESIN 1466 Score = 30.8 bits (68), Expect = 1.5 Identities = 25/126 (19%), Positives = 58/126 (46%), Gaps = 1/126 (0%) Frame = +3 Query: 18 IQEEQLKSMQAEMARLS-LEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEM 194 I + KS++ + +L +EK + ++ ++ ++E TSK + ++ EL Sbjct: 1061 ISSQTNKSLEDKTNQLKYIEKNVQKLLDEKDQRNVELEELTSKYGKLGEENAQIKDELLA 1120 Query: 195 IREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHIXND 374 +R++++K D + + D + L N + +L + + +AL E S + N Sbjct: 1121 LRKKSKKQHDLCANFVDDLKEKSDALEQLTNEKNELIVSLEQSNSNNEALVEERSDLANR 1180 Query: 375 RGDVER 392 D+++ Sbjct: 1181 LSDMKK 1186 Score = 28.1 bits (61), Expect = 9.7 Identities = 34/121 (28%), Positives = 57/121 (47%), Gaps = 5/121 (4%) Frame = +3 Query: 6 LSVSIQEEQL--KSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQ 179 + S+ EEQ KS++ E R LEK L + + L ++ ++CK LQ Sbjct: 234 IKASLAEEQASNKSLRGEQER--LEKLLVSSNKTVSTLRQTENSLRAECK-------TLQ 284 Query: 180 KELE--MIREENRK-LDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQH 350 ++LE I EE+ K L++ H+ + D I+ + KL E++S + E L+ Sbjct: 285 EKLEKCAINEEDSKLLEELKHN----VANYSDAIVH----KDKLIEDLSTRISEFDNLKS 336 Query: 351 E 353 E Sbjct: 337 E 337
>MLP2_YEAST (P40457) Protein MLP2 (Myosin-like protein 2)| Length = 1679 Score = 41.2 bits (95), Expect = 0.001 Identities = 34/138 (24%), Positives = 68/138 (49%), Gaps = 8/138 (5%) Frame = +3 Query: 24 EEQLKSMQAEMAR--LSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKL--MLQKELE 191 E ++KS+ E++ ++EK ++++ + L K ++ +AS L L+KELE Sbjct: 823 EMKMKSLLTELSNKETTIEKLSSEIENLDKELRKTKFQYKFLDQNSDASTLEPTLRKELE 882 Query: 192 MIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVE----EKKALQHELS 359 I+ + + + Q + +I ++ +I LKN K +E +E EK A + +LS Sbjct: 883 QIQVQLKDANSQIQAYEEIISSNENALIELKNELAKTKENYDAKIELEKKEKWAREEDLS 942 Query: 360 HIXNDRGDVERKHFSIKE 413 + + G++ +KE Sbjct: 943 RLRGELGEIRALQPKLKE 960 Score = 32.3 bits (72), Expect = 0.51 Identities = 18/88 (20%), Positives = 41/88 (46%) Frame = +3 Query: 132 ETSKCKDVEASKLMLQKELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEE 311 E ++ ++ + +LQK L+ + E+NR++ Q + I RLQ ++I K + Sbjct: 1169 EVTQVNILKENNAILQKSLKNVTEKNREIYKQLNDRQEEISRLQRDLIQTKEQVSINSNK 1228 Query: 312 VSRHVEEKKALQHELSHIXNDRGDVERK 395 + + E + + + + D ++K Sbjct: 1229 ILVYESEMEQCKQRYQDLSQQQKDAQKK 1256
>MRCKB_HUMAN (Q9Y5S2) Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1)| (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta) Length = 1711 Score = 41.2 bits (95), Expect = 0.001 Identities = 26/101 (25%), Positives = 53/101 (52%) Frame = +3 Query: 48 AEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIREENRKLDDQ 227 +E +L+L+K++ +++KL E+H E + V K ++E M+ +EN+KL + Sbjct: 722 SESHQLALQKEILMLKDKLEKSKRERHNEMEEA--VGTIKDKYERERAMLFDENKKLTAE 779 Query: 228 NHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQH 350 N S + +L + R+LE+E+ +K+++ H Sbjct: 780 NEKLCSFVDKLTAQ-------NRQLEDELQDLAAKKESVAH 813 Score = 30.8 bits (68), Expect = 1.5 Identities = 29/96 (30%), Positives = 50/96 (52%), Gaps = 1/96 (1%) Frame = +3 Query: 3 KLSVSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQK 182 KL +S + E +++AE+ KQL VQE+LR + SK KD EA L + Sbjct: 870 KLDMSARLELQSALEAEIRA----KQL--VQEELRKVKDANLTLESKLKDSEAKNRELLE 923 Query: 183 ELEMIREENRKLDDQNHSSTSV-IIRLQDEIISLKN 287 E+E+++ +K++++ + T + + QD I N Sbjct: 924 EMEILK---KKMEEKFRADTGLKLPDFQDSIFEYFN 956
>MYSN_DROME (Q99323) Myosin heavy chain, non-muscle (Zipper protein) (Myosin II)| (Non-muscle MHC) Length = 2057 Score = 40.8 bits (94), Expect = 0.001 Identities = 35/124 (28%), Positives = 54/124 (43%), Gaps = 2/124 (1%) Frame = +3 Query: 18 IQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLM--LQKELE 191 I EE A+ A+ LE QLA++QE L E K +A K+ L +ELE Sbjct: 1183 IDEESATKATAQKAQRELESQLAEIQEDL---------EAEKAARAKAEKVRRDLSEELE 1233 Query: 192 MIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHIXN 371 ++ E D + + + + E+ +LK + LEEE H ++H+ S N Sbjct: 1234 ALKNELLDSLDTTAAQQELRSKREQELATLK---KSLEEETVNHEGVLADMRHKHSQELN 1290 Query: 372 DRGD 383 D Sbjct: 1291 SIND 1294 Score = 37.4 bits (85), Expect = 0.016 Identities = 36/151 (23%), Positives = 64/151 (42%), Gaps = 10/151 (6%) Frame = +3 Query: 6 LSVSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKE 185 L+ ++ + + R E Q+A++Q KL + + KC LQ+E Sbjct: 1320 LATELRSVNSSRQENDRRRKQAESQIAELQVKLAEIERARSELQEKCTK-------LQQE 1372 Query: 186 LEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVS---------RHVE-EK 335 E I + L++ +++ + + L AQ+ LEEE R +E EK Sbjct: 1373 AENITNQ---LEEAELKASAAVKSASNMESQLTEAQQLLEEETRQKLGLSSKLRQIESEK 1429 Query: 336 KALQHELSHIXNDRGDVERKHFSIKEQIQAV 428 +ALQ +L + + ERK + Q+Q + Sbjct: 1430 EALQEQLEEDDEAKRNYERKLAEVTTQMQEI 1460 Score = 31.2 bits (69), Expect = 1.1 Identities = 29/139 (20%), Positives = 61/139 (43%) Frame = +3 Query: 3 KLSVSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQK 182 +L++ EEQL+ +A +L LEK Q+ K++ K+ E D + KL+ +K Sbjct: 1033 ELNIQDLEEQLEEEEAARQKLQLEK--VQLDAKIK-----KYEEDLALTDDQNQKLLKEK 1085 Query: 183 ELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSH 362 +L L+++ + + + +++ L + K E ++ E Q + Sbjct: 1086 KL---------LEERANDLSQTLAEEEEKAKHLAKLKAKHEATITELEERLHKDQQQRQE 1136 Query: 363 IXNDRGDVERKHFSIKEQI 419 + +E + +KEQ+ Sbjct: 1137 SDRSKRKIETEVADLKEQL 1155
>HOOK2_MOUSE (Q7TMK6) Hook homolog 2| Length = 716 Score = 40.8 bits (94), Expect = 0.001 Identities = 31/136 (22%), Positives = 63/136 (46%), Gaps = 6/136 (4%) Frame = +3 Query: 24 EEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIRE 203 + QL+ +Q E RL ++ ++LR L LE+ E ++ + + L +E + +++ Sbjct: 242 QSQLEQLQEENFRLESSRE----DDRLRCLELER--EVAELQQRNQALTSLSQEAQALKD 295 Query: 204 ENRKLDDQNHSSTSVIIRLQD------EIISLKNAQRKLEEEVSRHVEEKKALQHELSHI 365 E +L + + + L E+ L+ R+LEE + H E + L+ EL Sbjct: 296 EMDELRQSSERARQLEATLNSCRRRLGELQELRRQVRQLEERNAGHAERTRQLEEELRRA 355 Query: 366 XNDRGDVERKHFSIKE 413 + R +E + ++E Sbjct: 356 GSLRAQLEAQRRQVQE 371 Score = 31.6 bits (70), Expect = 0.87 Identities = 35/144 (24%), Positives = 61/144 (42%), Gaps = 13/144 (9%) Frame = +3 Query: 24 EEQLKSMQAEMARLSLEKQ-LAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQK-ELEMI 197 EE+ + E RL E+ L + E+LR L+ G ++ + L+ E++ Sbjct: 394 EEKCDLVTKEKERLLTERDSLREANEELRCAQLQPRGLAQADLSLDPTPSGLENLAAEIL 453 Query: 198 REENRKLDDQNHSSTSVIIRLQDE---IISLKNAQRKLEEEVSRHVEEKKALQHEL---- 356 E R+ ++RLQ E + + A R+ +EE+ RH+EE +H L Sbjct: 454 PAELRE----------TLVRLQLENKRLCQQEAADRERQEELQRHLEEANRARHGLEAQQ 503 Query: 357 ----SHIXNDRGDVERKHFSIKEQ 416 + R VE +++EQ Sbjct: 504 RLNQQQLSELRAQVEELQKALQEQ 527
>MYO4_CAEEL (P02566) Myosin-4 (Myosin heavy chain B) (MHC B) (Uncoordinated| protein 54) Length = 1966 Score = 40.8 bits (94), Expect = 0.001 Identities = 34/131 (25%), Positives = 59/131 (45%) Frame = +3 Query: 3 KLSVSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQK 182 K +S EE+L ++A+ S KQL+++ ++L K +EA L+K Sbjct: 907 KTQLSDAEERLAKLEAQQKDAS--KQLSELNDQLADNEDRTADVQRAKKKIEAEVEALKK 964 Query: 183 ELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSH 362 +++ + RK + + S I LQDE+ A KL +E E + L +L Sbjct: 965 QIQDLEMSLRKAESEKQSKDHQIRSLQDEMQQQDEAIAKLNKEKKHQEEINRKLMEDLQS 1024 Query: 363 IXNDRGDVERK 395 D+G+ + K Sbjct: 1025 -EEDKGNHQNK 1034 Score = 28.5 bits (62), Expect = 7.4 Identities = 29/108 (26%), Positives = 52/108 (48%), Gaps = 4/108 (3%) Frame = +3 Query: 117 LEKHGETSKC-KDVEASKLMLQKELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQ 293 LEK + K +D A + L+KELE E + KL ++ TS+ L+ L +A+ Sbjct: 861 LEKINDKVKALEDSLAKEEKLRKELE---ESSAKLVEE---KTSLFTNLESTKTQLSDAE 914 Query: 294 R---KLEEEVSRHVEEKKALQHELSHIXNDRGDVERKHFSIKEQIQAV 428 KLE + ++ L +L+ + DV+R I+ +++A+ Sbjct: 915 ERLAKLEAQQKDASKQLSELNDQLADNEDRTADVQRAKKKIEAEVEAL 962 Score = 28.1 bits (61), Expect = 9.7 Identities = 18/72 (25%), Positives = 34/72 (47%) Frame = +3 Query: 201 EENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHIXNDRG 380 EE K++D+ + L+D + + +++LEE ++ VEEK +L L Sbjct: 859 EELEKINDK-------VKALEDSLAKEEKLRKELEESSAKLVEEKTSLFTNLESTKTQLS 911 Query: 381 DVERKHFSIKEQ 416 D E + ++ Q Sbjct: 912 DAEERLAKLEAQ 923
>ROCK1_MOUSE (P70335) Rho-associated protein kinase 1 (EC 2.7.11.1)| (Rho-associated, coiled-coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) Length = 1354 Score = 40.4 bits (93), Expect = 0.002 Identities = 38/139 (27%), Positives = 70/139 (50%), Gaps = 5/139 (3%) Frame = +3 Query: 6 LSVSIQEEQLKSMQAEMARLSLEKQLAQV-QEKLRLLSLEKHGETSKCKDV---EASKLM 173 LS + + K+ ++AR LE+Q ++ QE + S + T K V E + + Sbjct: 888 LSTQLDLAETKAESEQLARGILEEQYFELTQESKKAASRNRQEITDKDHTVSRLEETNSV 947 Query: 174 LQKELEMIREENRKLDDQNHSSTSVI-IRLQDEIISLKNAQRKLEEEVSRHVEEKKALQH 350 L K++EM+R+EN +L+++ ++ ++ ++EI +LK A E+ +S K + Sbjct: 948 LTKDIEMLRKENEELNERMRTAEEEYKLKKEEEINNLKAA---FEKNISTERTLKTQAVN 1004 Query: 351 ELSHIXNDRGDVERKHFSI 407 +L+ I N RK F I Sbjct: 1005 KLAEIMN------RKDFKI 1017 Score = 34.7 bits (78), Expect = 0.10 Identities = 26/128 (20%), Positives = 64/128 (50%) Frame = +3 Query: 9 SVSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKEL 188 S + E + S + + SL+K + +++E+L K KC+ S L L K + Sbjct: 408 SANASENRSSSNVDKSLQESLQKTIYKLEEQLHNEMQLKDEMEQKCR---TSNLKLDKIM 464 Query: 189 EMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHIX 368 + + EE +Q + S + +++ E + L++ + + +V + E+++ +++E+S + Sbjct: 465 KELDEEG----NQRRNLESAVSQIEKEKMLLQHRINEYQRKVEQENEKRRNIENEVSTLK 520 Query: 369 NDRGDVER 392 + D+ + Sbjct: 521 DQLEDLRK 528 Score = 32.7 bits (73), Expect = 0.39 Identities = 35/122 (28%), Positives = 59/122 (48%), Gaps = 2/122 (1%) Frame = +3 Query: 30 QLKSMQAEMARL--SLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIRE 203 +L+ EM++ LE ++QE+ R+L E SK +A K Q L+ + E Sbjct: 563 RLRKSHTEMSKSISQLESLNRELQERNRIL------ENSKS---QADKDYYQ--LQAVLE 611 Query: 204 ENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHIXNDRGD 383 R+ D+ H S +I LQ I SL+ + L+ + R E+K Q L+H ++ + Sbjct: 612 AERR--DRGHDS-EMIGDLQARITSLQEEVKHLKHNLERVEGERKEAQDMLNHSEKEKNN 668 Query: 384 VE 389 +E Sbjct: 669 LE 670
>SLA2_SCHPO (Q9P6L5) Endocytosis protein end4 (SLA2 protein homolog)| Length = 1092 Score = 40.4 bits (93), Expect = 0.002 Identities = 38/143 (26%), Positives = 63/143 (44%), Gaps = 20/143 (13%) Frame = +3 Query: 24 EEQLKSMQAEMARLSLEKQLAQ----------------VQEKLRLLSLEKHGETSKCKDV 155 E ++K+ E+A + LE+ A+ + +LRLL EK + K Sbjct: 523 EREMKNKNLELADMILERDRARHELETMHRSQRDKQESTERELRLLQ-EKAASLERNKSS 581 Query: 156 EASKLMLQKELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEK 335 E S L+ + E+ L+D HS + L E+ S +N R+L +E +E + Sbjct: 582 EVSNLLSRYNTEVAH-----LEDALHSKDRELANLGVELKSTENRYRQLLQEKEEELEIQ 636 Query: 336 KALQHE----LSHIXNDRGDVER 392 KA E LS + DR D+++ Sbjct: 637 KAAVDESLLQLSKLQLDRNDIDQ 659
>MYS_AEQIR (P24733) Myosin heavy chain, striated muscle| Length = 1938 Score = 40.4 bits (93), Expect = 0.002 Identities = 37/145 (25%), Positives = 70/145 (48%), Gaps = 5/145 (3%) Frame = +3 Query: 3 KLSVSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCK-DVEASKLMLQ 179 K S S+Q E+ K + LE+ L ++++ L + G+ K K VE Q Sbjct: 1002 KTSDSLQAEEDKCNHLNKLKAKLEQALDELEDNLER-EKKVRGDVEKAKRKVEQDLKSTQ 1060 Query: 180 KELEMIREENRKLDD----QNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQ 347 + +E + R+L++ + +S+ +L+DE + QRK++E +R +EE L+ Sbjct: 1061 ENVEDLERVKRELEENVRRKEAEISSLNSKLEDEQNLVSQLQRKIKELQAR-IEE---LE 1116 Query: 348 HELSHIXNDRGDVERKHFSIKEQIQ 422 EL N R VE++ + +++ Sbjct: 1117 EELEAERNARAKVEKQRAELNRELE 1141 Score = 37.7 bits (86), Expect = 0.012 Identities = 31/145 (21%), Positives = 67/145 (46%), Gaps = 12/145 (8%) Frame = +3 Query: 24 EEQLKSMQAEMARLS------------LEKQLAQVQEKLRLLSLEKHGETSKCKDVEASK 167 EE ++ +AE++ L+ L++++ ++Q ++ L E E + VE + Sbjct: 1074 EENVRRKEAEISSLNSKLEDEQNLVSQLQRKIKELQARIEELEEELEAERNARAKVEKQR 1133 Query: 168 LMLQKELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQ 347 L +ELE + E +LD+ ++++ I + L +R LEE +H + AL+ Sbjct: 1134 AELNRELEELGE---RLDEAGGATSAQIELNKKREAELLKIRRDLEEASLQHEAQISALR 1190 Query: 348 HELSHIXNDRGDVERKHFSIKEQIQ 422 + N+ D + +K +++ Sbjct: 1191 KKHQDAANEMADQVDQLQKVKSKLE 1215 Score = 36.6 bits (83), Expect = 0.027 Identities = 31/146 (21%), Positives = 65/146 (44%), Gaps = 12/146 (8%) Frame = +3 Query: 21 QEEQLKSMQAEMARLS-----LEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKE 185 ++ Q+ ++Q E+++ L K+ ++E + S E KC + K L++ Sbjct: 968 KDNQISTLQGEISQQDEHIGKLNKEKKALEEANKKTSDSLQAEEDKCNHLNKLKAKLEQA 1027 Query: 186 LEMIRE----ENRKLDDQNHSSTSV---IIRLQDEIISLKNAQRKLEEEVSRHVEEKKAL 344 L+ + + E + D + V + Q+ + L+ +R+LEE V R E +L Sbjct: 1028 LDELEDNLEREKKVRGDVEKAKRKVEQDLKSTQENVEDLERVKRELEENVRRKEAEISSL 1087 Query: 345 QHELSHIXNDRGDVERKHFSIKEQIQ 422 +L N ++RK ++ +I+ Sbjct: 1088 NSKLEDEQNLVSQLQRKIKELQARIE 1113 Score = 28.5 bits (62), Expect = 7.4 Identities = 25/118 (21%), Positives = 46/118 (38%) Frame = +3 Query: 69 LEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIREENRKLDDQNHSSTSV 248 LE Q ++ KL +KC +E +K LQ+ELE + E Sbjct: 1383 LEDQKRKLLGKLSEAEQTTEAANAKCSALEKAKSRLQQELEDMSIE-------------- 1428 Query: 249 IIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHIXNDRGDVERKHFSIKEQIQ 422 + R + ++ QR ++ + + +LQ EL + + + + IK I+ Sbjct: 1429 VDRANASVNQMEKKQRAFDKTTAEWQAKVNSLQSELENSQKESRGYSAELYRIKASIE 1486 Score = 28.5 bits (62), Expect = 7.4 Identities = 28/149 (18%), Positives = 67/149 (44%), Gaps = 11/149 (7%) Frame = +3 Query: 9 SVSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKC----KDVEASKLML 176 S+ QEE+++ + M + E Q+ +++E+L L++ + K +EA L Sbjct: 894 SMGDQEERVEKLI--MQKADFESQIKELEERL----LDEEDAAADLEGIKKKMEADNANL 947 Query: 177 QKELEMIREENRKLDDQNHSSTSVIIRLQDEIIS-------LKNAQRKLEEEVSRHVEEK 335 +K++ + +K + + I LQ EI L ++ LEE + + Sbjct: 948 KKDIGDLENTLQKAEQDKAHKDNQISTLQGEISQQDEHIGKLNKEKKALEEANKKTSDSL 1007 Query: 336 KALQHELSHIXNDRGDVERKHFSIKEQIQ 422 +A + + +H+ + +E+ +++ ++ Sbjct: 1008 QAEEDKCNHLNKLKAKLEQALDELEDNLE 1036
>CYTSA_MOUSE (Q2KN98) Cytospin-A| Length = 1118 Score = 40.4 bits (93), Expect = 0.002 Identities = 33/145 (22%), Positives = 73/145 (50%), Gaps = 6/145 (4%) Frame = +3 Query: 6 LSVSIQEEQ--LKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQ 179 L+ +++E + + S Q EM RL + + + Q+ L S+ G+ S +D+ S + + Sbjct: 559 LAATLEEYKATVASDQIEMNRLKAQLE-NEKQKVAELYSIHNSGDKSDIQDLLESVRLDK 617 Query: 180 KELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEE----KKALQ 347 ++ E + + +D H+ RLQD I +++ R +EE + +E+ + L+ Sbjct: 618 EKAETLASSLQ--EDLAHTRNDAN-RLQDTIAKVEDEYRAFQEEAKKQIEDLNMTLEKLR 674 Query: 348 HELSHIXNDRGDVERKHFSIKEQIQ 422 EL +R D++ F ++++++ Sbjct: 675 SELEEKDTERSDMKETIFELEDEVE 699
>MYH8_HUMAN (P13535) Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal)| (MyHC-perinatal) Length = 1937 Score = 40.4 bits (93), Expect = 0.002 Identities = 28/135 (20%), Positives = 68/135 (50%) Frame = +3 Query: 24 EEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIRE 203 E + K ++ +M L EK Q+Q + SL E +C+ + +K+ L+ +++ + E Sbjct: 870 EAKRKELEEKMVTLLKEKNDLQLQVQSEADSLADAEE--RCEQLIKNKIQLEAKIKEVTE 927 Query: 204 ENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHIXNDRGD 383 + ++ N T+ +L+DE LK LE +++ +EK A ++++ ++ + Sbjct: 928 RAEEEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAG 987 Query: 384 VERKHFSIKEQIQAV 428 ++ + ++ +A+ Sbjct: 988 LDETIAKLSKEKKAL 1002 Score = 36.6 bits (83), Expect = 0.027 Identities = 37/134 (27%), Positives = 67/134 (50%), Gaps = 13/134 (9%) Frame = +3 Query: 24 EEQLKSMQA---EMARLSLEKQLAQVQE-KLRLLSLEKHGETSKCKDVEASKLMLQ---- 179 E+ +K +Q E +L+L+ Q+Q+ + R+ LE E + ++ EA K + + Sbjct: 1790 EQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERR 1849 Query: 180 -KELEMIREENRK----LDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKAL 344 KEL EE+RK L D ++ +LQ ++ S K + EE+ + ++ + + L Sbjct: 1850 VKELTYQTEEDRKNVLRLQD-------LVDKLQAKVKSYKRQAEEAEEQSNANLSKFRKL 1902 Query: 345 QHELSHIXNDRGDV 386 QHEL +R D+ Sbjct: 1903 QHELEE-AEERADI 1915 Score = 36.2 bits (82), Expect = 0.035 Identities = 32/145 (22%), Positives = 67/145 (46%), Gaps = 5/145 (3%) Frame = +3 Query: 3 KLSVSIQE--EQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLML 176 KL+ +QE E ++++ A+ A SLEK ++Q ++ L L+ + C ++ + Sbjct: 1395 KLAQRLQEAEEHVEAVNAKCA--SLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNF 1452 Query: 177 QKELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHEL 356 K L +++ + + +S L E+ +KN + +++ E K LQ E+ Sbjct: 1453 DKVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEI 1512 Query: 357 SHIXN---DRGDVERKHFSIKEQIQ 422 S + + G + IK+Q++ Sbjct: 1513 SDLTEQIAEGGKQIHELEKIKKQVE 1537 Score = 35.0 bits (79), Expect = 0.079 Identities = 29/124 (23%), Positives = 52/124 (41%), Gaps = 7/124 (5%) Frame = +3 Query: 48 AEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELE----MIREENRK 215 A+ + + +E Q+ EKL E SK +D +A ++ LQK+++ I E + Sbjct: 1065 AQESTMDMENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEE 1124 Query: 216 LDDQNHSSTSVIIRLQDEIISLKNAQRKLEE---EVSRHVEEKKALQHELSHIXNDRGDV 386 ++ + S + D L+ +LEE S VE K + E + D + Sbjct: 1125 IEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEA 1184 Query: 387 ERKH 398 +H Sbjct: 1185 TLQH 1188 Score = 32.3 bits (72), Expect = 0.51 Identities = 28/130 (21%), Positives = 59/130 (45%), Gaps = 7/130 (5%) Frame = +3 Query: 6 LSVSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGE-------TSKCKDVEAS 164 L + +Q E AE L K Q++ K++ ++ E T+K + +E Sbjct: 890 LQLQVQSEADSLADAEERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDE 949 Query: 165 KLMLQKELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKAL 344 L+K+++ + K++ + H++ + + L +E+ L +E +++ +EKKAL Sbjct: 950 CSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGL-------DETIAKLSKEKKAL 1002 Query: 345 QHELSHIXND 374 Q +D Sbjct: 1003 QETHQQTLDD 1012 Score = 30.0 bits (66), Expect = 2.5 Identities = 28/98 (28%), Positives = 48/98 (48%), Gaps = 4/98 (4%) Frame = +3 Query: 72 EKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIREENRKLDDQNHSSTSVI 251 + +L Q++ R LS E K K+V L +LE +R EN+ L + T I Sbjct: 1467 QAELEASQKESRSLSTELF----KVKNVYEESL---DQLETLRRENKNLQQEISDLTEQI 1519 Query: 252 IRLQDEIISLKNAQRKLEE---EVSRHVEEKKA-LQHE 353 +I L+ ++++E+ E+ +EE +A L+HE Sbjct: 1520 AEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHE 1557
>HOOK2_HUMAN (Q96ED9) Hook homolog 2 (h-hook2) (hHK2)| Length = 719 Score = 40.0 bits (92), Expect = 0.002 Identities = 32/135 (23%), Positives = 64/135 (47%), Gaps = 5/135 (3%) Frame = +3 Query: 24 EEQLKSMQAEMARLSLEKQ-----LAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKEL 188 + QL+ +Q E RL ++ A+++ ++ L TS ++ +A L+ E+ Sbjct: 242 QSQLEQLQEENFRLESGREDERLRCAELEREVAELQHRNQALTSLAQEAQA----LKDEM 297 Query: 189 EMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHIX 368 + +R+ + + + TS RL E+ L+ R+LEE + H E + L+ EL Sbjct: 298 DELRQSSERAGQLEATLTSCRRRL-GELRELRRQVRQLEERNAGHAERTRQLEDELRRAG 356 Query: 369 NDRGDVERKHFSIKE 413 + R +E + ++E Sbjct: 357 SLRAQLEAQRRQVQE 371 Score = 34.7 bits (78), Expect = 0.10 Identities = 37/144 (25%), Positives = 64/144 (44%), Gaps = 13/144 (9%) Frame = +3 Query: 24 EEQLKSMQAEMARLSLEKQ-LAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQK-ELEMI 197 EE+ +S+ E RL E+ L + E+LR L+ G T ++ + + E++ Sbjct: 394 EEKYESVTKEKERLLAERDSLREANEELRCAQLQPRGLTQADPSLDPTSTPVDNLAAEIL 453 Query: 198 REENRKLDDQNHSSTSVIIRLQDE---IISLKNAQRKLEEEVSRHVEEKKALQH--ELSH 362 E R+ ++RLQ E + + A R+ +EE+ RH+E+ +H E H Sbjct: 454 PAELRE----------TLLRLQLENKRLCRQEAADRERQEELQRHLEDANRARHGLETQH 503 Query: 363 IXND------RGDVERKHFSIKEQ 416 N R VE +++EQ Sbjct: 504 RLNQQQLSELRAQVEDLQKALQEQ 527
>VDP_HUMAN (O60763) General vesicular transport factor p115| (Transcytosis-associated protein) (TAP) (Vesicle docking protein) Length = 962 Score = 40.0 bits (92), Expect = 0.002 Identities = 43/152 (28%), Positives = 71/152 (46%), Gaps = 12/152 (7%) Frame = +3 Query: 3 KLSVSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGET-----SKCKDVEA-- 161 K ++ + QL S E+ +L EKQ + + S+E GET +K DVE Sbjct: 791 KQELATLKSQLNSQSVEITKLQTEKQELLQKTEAFAKSVEVQGETETIIATKTTDVEGRL 850 Query: 162 SKLM-----LQKELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHV 326 S L+ L+ E++ + EE + +Q SS S I LQ E + KLE E++ Sbjct: 851 SALLQETKELKNEIKALSEERTAIKEQLDSSNSTIAILQTE-------KDKLELEITDSK 903 Query: 327 EEKKALQHELSHIXNDRGDVERKHFSIKEQIQ 422 +E+ L L+ D ++K S+K +++ Sbjct: 904 KEQDDLLVLLA-------DQDQKILSLKNKLK 928
>CCHCR_MOUSE (Q8K2I2) Coiled-coil alpha-helical rod protein 1 (Alpha helical| coiled-coil rod protein) Length = 770 Score = 40.0 bits (92), Expect = 0.002 Identities = 35/141 (24%), Positives = 69/141 (48%), Gaps = 3/141 (2%) Frame = +3 Query: 15 SIQEEQLKSM-QAEMARL-SLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKEL 188 S+ +EQL S+ QA L SL + +++ L L ++ GE + M QKE Sbjct: 173 SLHQEQLSSLTQAHQKALDSLASKAEGLEKSLNSLETKRAGEAKQLA-------MAQKEA 225 Query: 189 EMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVE-EKKALQHELSHI 365 +M+R + K ++ + +++ L+ + ++ L E S+ E E+K L L H+ Sbjct: 226 DMLRNQLSKTQEELEAQVTLVESLRKYV-----GEQVLPEFPSQEWELERKELLDTLKHL 280 Query: 366 XNDRGDVERKHFSIKEQIQAV 428 DR D++ ++ ++Q++ Sbjct: 281 KEDRADLQATVELLQVRVQSL 301
>SMC3_RAT (P97690) Structural maintenance of chromosome 3 (Chondroitin| sulfate proteoglycan 6) (Chromosome segregation protein SmcD) (Bamacan) (Basement membrane-associated chondroitin proteoglycan) Length = 1191 Score = 39.7 bits (91), Expect = 0.003 Identities = 28/137 (20%), Positives = 64/137 (46%) Frame = +3 Query: 6 LSVSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKE 185 L +I ++L +A++ LS +++ + EK R L + K +D+E L+ + Sbjct: 223 LEYTIYNQELNETRAKLDELSAKRETSG--EKSRQLRDAQQDARDKMEDIERQVRELKTK 280 Query: 186 LEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHI 365 + ++EE +L + +L+ + L++ E+ R ++E++ L ++ Sbjct: 281 ISAMKEEKEQLSAERQEQIKQRTKLELKAKDLQDELAGNSEQRKRLLKERQKLLEKIEEK 340 Query: 366 XNDRGDVERKHFSIKEQ 416 + + E K S+KE+ Sbjct: 341 QKELAETEPKFNSVKEK 357
>USO1_YEAST (P25386) Intracellular protein transport protein USO1 (Int-1)| Length = 1790 Score = 39.7 bits (91), Expect = 0.003 Identities = 36/128 (28%), Positives = 67/128 (52%), Gaps = 12/128 (9%) Frame = +3 Query: 27 EQLKSMQAEMARLS--------LEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQK 182 E +KS+++E ++ EK+++++++KL+ +D + L LQK Sbjct: 1248 ESIKSVESETVKIKELQDECNFKEKEVSELEDKLKA-----------SEDKNSKYLELQK 1296 Query: 183 ELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSR----HVEEKKALQH 350 E E I+EE LD + +T + I+L ++I +L A+ K E E+SR EE+K + Sbjct: 1297 ESEKIKEE---LDAK---TTELKIQL-EKITNLSKAKEKSESELSRLKKTSSEERKNAEE 1349 Query: 351 ELSHIXND 374 +L + N+ Sbjct: 1350 QLEKLKNE 1357 Score = 38.9 bits (89), Expect = 0.005 Identities = 32/140 (22%), Positives = 65/140 (46%) Frame = +3 Query: 3 KLSVSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQK 182 K ++ +E+L S++ + R L ++E+LR K K +E + Sbjct: 1444 KDKITRNDEKLLSIERDNKR-----DLESLKEQLRAAQESKAKVEEGLKKLEEESSKEKA 1498 Query: 183 ELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSH 362 ELE +E +KL+ S+ + L+ + +++ + KLE+ E+ K LQHE S Sbjct: 1499 ELEKSKEMMKKLESTIESNET---ELKSSMETIRKSDEKLEQSKKSAEEDIKNLQHEKSD 1555 Query: 363 IXNDRGDVERKHFSIKEQIQ 422 + + + E+ +K +++ Sbjct: 1556 LISRINESEKDIEELKSKLR 1575 Score = 36.2 bits (82), Expect = 0.035 Identities = 34/120 (28%), Positives = 58/120 (48%) Frame = +3 Query: 66 SLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIREENRKLDDQNHSSTS 245 +++++L QEK+R+ + E SK +D+E Q E++ +EE L TS Sbjct: 1586 TVKQELNNAQEKIRINAEENTVLKSKLEDIERELKDKQAEIKSNQEEKELL-------TS 1638 Query: 246 VIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHIXNDRGDVERKHFSIKEQIQA 425 + L+ E+ S + +K EEE R E +K Q E S + +E K+ + + QA Sbjct: 1639 RLKELEQELDSTQQKAQKSEEE--RRAEVRK-FQVEKSQLDEKAMLLETKYNDLVNKEQA 1695
>MYH8_MOUSE (P13542) Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal)| (MyHC-perinatal) Length = 1937 Score = 39.7 bits (91), Expect = 0.003 Identities = 28/135 (20%), Positives = 67/135 (49%) Frame = +3 Query: 24 EEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIRE 203 E + K ++ +M L EK Q+Q + SL E +C+ + +K+ L+ +++ + E Sbjct: 870 EAKRKELEEKMVTLLKEKNDLQLQVQSEADSLADAEE--RCEQLIKNKIQLEAKIKEVTE 927 Query: 204 ENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHIXNDRGD 383 ++ N T+ +L+DE LK LE +++ +EK A ++++ ++ + Sbjct: 928 RAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAG 987 Query: 384 VERKHFSIKEQIQAV 428 ++ + ++ +A+ Sbjct: 988 LDENIAKLTKEKKAL 1002 Score = 36.2 bits (82), Expect = 0.035 Identities = 37/134 (27%), Positives = 67/134 (50%), Gaps = 13/134 (9%) Frame = +3 Query: 24 EEQLKSMQA---EMARLSLEKQLAQVQE-KLRLLSLEKHGETSKCKDVEASKLMLQ---- 179 E+ +K +Q E +L+L+ Q+Q+ + R+ LE E + ++ EA K + + Sbjct: 1790 EQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERR 1849 Query: 180 -KELEMIREENRK----LDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKAL 344 KEL EE+RK L D ++ +LQ ++ S K + EE+ + ++ + + L Sbjct: 1850 VKELTYQTEEDRKNVLRLQD-------LVDKLQAKVKSYKRQAEEAEEQSNANLAKFRKL 1902 Query: 345 QHELSHIXNDRGDV 386 QHEL +R D+ Sbjct: 1903 QHELEE-AEERADI 1915 Score = 36.2 bits (82), Expect = 0.035 Identities = 29/124 (23%), Positives = 53/124 (42%), Gaps = 7/124 (5%) Frame = +3 Query: 48 AEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELE----MIREENRK 215 A+ + + +E Q+ EKL+ E SK +D +A ++ LQK+++ I E + Sbjct: 1065 AQESTMDIENDKQQLDEKLKKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELEEE 1124 Query: 216 LDDQNHSSTSVIIRLQDEIISLKNAQRKLEE---EVSRHVEEKKALQHELSHIXNDRGDV 386 ++ + S + D L+ +LEE S VE K + E + D + Sbjct: 1125 IEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQVEMNKKRETEFQKLRRDLEEA 1184 Query: 387 ERKH 398 +H Sbjct: 1185 TLQH 1188 Score = 33.9 bits (76), Expect = 0.18 Identities = 28/130 (21%), Positives = 59/130 (45%), Gaps = 7/130 (5%) Frame = +3 Query: 6 LSVSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGE-------TSKCKDVEAS 164 L + +Q E AE L K Q++ K++ ++ E T+K + +E Sbjct: 890 LQLQVQSEADSLADAEERCEQLIKNKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDE 949 Query: 165 KLMLQKELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKAL 344 L+K+++ + K++ + H++ + + L +E+ L +E +++ +EKKAL Sbjct: 950 CSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGL-------DENIAKLTKEKKAL 1002 Query: 345 QHELSHIXND 374 Q +D Sbjct: 1003 QEAHQQTLDD 1012 Score = 32.0 bits (71), Expect = 0.67 Identities = 30/141 (21%), Positives = 67/141 (47%) Frame = +3 Query: 3 KLSVSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQK 182 +L + I + + A+ +LEK +++++ L ++ + ++ A + LQ Sbjct: 1226 ELKMEIDDLSSNAEAIAKAKGNLEKMCRTLEDQVSELKSKEEEQQRLINELTAQRARLQT 1285 Query: 183 ELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSH 362 E E +R+LD+++ + + Q ++ +R+LEEE + K AL H L Sbjct: 1286 EAG---EYSRQLDEKDALVSQLSRSKQASTQQIEELKRQLEEE----TKAKNALAHALQS 1338 Query: 363 IXNDRGDVERKHFSIKEQIQA 425 +D D+ R+ + +++ +A Sbjct: 1339 SRHD-CDLLREQYEEEQEGKA 1358 Score = 28.1 bits (61), Expect = 9.7 Identities = 27/98 (27%), Positives = 45/98 (45%), Gaps = 4/98 (4%) Frame = +3 Query: 72 EKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIREENRKLDDQNHSSTSVI 251 + +L Q++ R LS E K K+ L LE +R EN+ L + T I Sbjct: 1467 QAELESCQKESRTLSTELF----KVKNAYEESL---DHLETLRRENKNLQQEISDLTEQI 1519 Query: 252 IRLQDEIISLKNAQRKLEE---EVSRHVEEKKA-LQHE 353 I L+ ++++E+ E+ +EE +A L+HE Sbjct: 1520 AEGGKHIHELEKIKKQVEQEKCEIQAALEEAEASLEHE 1557
>TAOK3_CHICK (Q9I9E0) Serine/threonine-protein kinase TAO3 (EC 2.7.11.1)| (Thousand and one amino acid protein 3) (Kinase from chicken) Length = 898 Score = 39.7 bits (91), Expect = 0.003 Identities = 34/142 (23%), Positives = 66/142 (46%), Gaps = 9/142 (6%) Frame = +3 Query: 3 KLSVSIQEEQLKSMQAEMARLSLEK---QLAQVQEKLRLLSLEKHGETSKCKDVEASKLM 173 K+ + E+ + + R+S K Q Q +E+ LLS ++ C+ + ++ Sbjct: 562 KIKEEMNEDHSTPKKEKQERISKHKENLQHTQAEEEAHLLSQQRLYYDKNCRFFKRKTMI 621 Query: 174 LQKELEM--IREENRKLDDQNHSSTSVIIRLQDEIISLKNAQ----RKLEEEVSRHVEEK 335 + ELE IREE K Q +++IR + L+ Q +KL ++ R ++ + Sbjct: 622 KRHELEQQNIREELNKKRTQKEMEHAMLIRHDESTRELEYRQLHTLQKLRMDLIR-LQHQ 680 Query: 336 KALQHELSHIXNDRGDVERKHF 401 L+++L + ++ RKHF Sbjct: 681 TELENQLEYNKRRERELHRKHF 702
>DYNA_XENLA (Q6PCJ1) Dynactin-1| Length = 1232 Score = 39.7 bits (91), Expect = 0.003 Identities = 26/121 (21%), Positives = 58/121 (47%) Frame = +3 Query: 66 SLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIREENRKLDDQNHSSTS 245 +L Q+ ++EKL L +++ + +K K++E SKL +LE ++E K+ +Q Sbjct: 177 NLRAQVKDLEEKLETLKMKRAEDKAKLKEMEKSKL----QLEQVQEWKSKMQEQQAD--- 229 Query: 246 VIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHIXNDRGDVERKHFSIKEQIQA 425 +Q ++ K ++ E R++EE + D+ E + S+++++ Sbjct: 230 ----IQRQLKEAKKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVDT 285 Query: 426 V 428 + Sbjct: 286 L 286
>SMC3_PONPY (Q5R4K5) Structural maintenance of chromosome 3 (Chondroitin| sulfate proteoglycan 6) Length = 1217 Score = 39.7 bits (91), Expect = 0.003 Identities = 28/137 (20%), Positives = 64/137 (46%) Frame = +3 Query: 6 LSVSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKE 185 L +I ++L +A++ LS +++ + EK R L + K +D+E L+ + Sbjct: 223 LEYTIYNQELNETRAKLDELSAKRETSG--EKSRQLRDAQQDARDKMEDIERQVRELKTK 280 Query: 186 LEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHI 365 + ++EE +L + +L+ + L++ E+ R ++E++ L ++ Sbjct: 281 ISAMKEEKEQLSAERQEQIKQRTKLELKAKDLQDELAGNSEQRKRLLKERQKLLEKIEEK 340 Query: 366 XNDRGDVERKHFSIKEQ 416 + + E K S+KE+ Sbjct: 341 QKELAETEPKFNSVKEK 357
>SMC3_MOUSE (Q9CW03) Structural maintenance of chromosome 3 (Chondroitin| sulfate proteoglycan 6) (Chromosome segregation protein SmcD) (Bamacan) (Basement membrane-associated chondroitin proteoglycan) (Mad member-interacting protein 1) Length = 1217 Score = 39.7 bits (91), Expect = 0.003 Identities = 28/137 (20%), Positives = 64/137 (46%) Frame = +3 Query: 6 LSVSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKE 185 L +I ++L +A++ LS +++ + EK R L + K +D+E L+ + Sbjct: 223 LEYTIYNQELNETRAKLDELSAKRETSG--EKSRQLRDAQQDARDKMEDIERQVRELKTK 280 Query: 186 LEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHI 365 + ++EE +L + +L+ + L++ E+ R ++E++ L ++ Sbjct: 281 ISAMKEEKEQLSAERQEQIKQRTKLELKAKDLQDELAGNSEQRKRLLKERQKLLEKIEEK 340 Query: 366 XNDRGDVERKHFSIKEQ 416 + + E K S+KE+ Sbjct: 341 QKELAETEPKFNSVKEK 357
>SMC3_HUMAN (Q9UQE7) Structural maintenance of chromosome 3 (Chondroitin| sulfate proteoglycan 6) (Chromosome-associated polypeptide) (hCAP) (Bamacan) (Basement membrane-associated chondroitin proteoglycan) Length = 1217 Score = 39.7 bits (91), Expect = 0.003 Identities = 28/137 (20%), Positives = 64/137 (46%) Frame = +3 Query: 6 LSVSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKE 185 L +I ++L +A++ LS +++ + EK R L + K +D+E L+ + Sbjct: 223 LEYTIYNQELNETRAKLDELSAKRETSG--EKSRQLRDAQQDARDKMEDIERQVRELKTK 280 Query: 186 LEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHI 365 + ++EE +L + +L+ + L++ E+ R ++E++ L ++ Sbjct: 281 ISAMKEEKEQLSAERQEQIKQRTKLELKAKDLQDELAGNSEQRKRLLKERQKLLEKIEEK 340 Query: 366 XNDRGDVERKHFSIKEQ 416 + + E K S+KE+ Sbjct: 341 QKELAETEPKFNSVKEK 357
>LMNA_HUMAN (P02545) Lamin-A/C (70 kDa lamin) (NY-REN-32 antigen)| Length = 664 Score = 39.7 bits (91), Expect = 0.003 Identities = 33/143 (23%), Positives = 66/143 (46%), Gaps = 6/143 (4%) Frame = +3 Query: 12 VSIQEEQLKSMQAEMARLSL-----EKQLAQVQEKLRLLSLEKHGETSKCKD-VEASKLM 173 +++ ++++S++ E A L L E+ +++ ++ + G+ K D V + Sbjct: 42 LAVYIDRVRSLETENAGLRLRITESEEVVSREVSGIKAAYEAELGDARKTLDSVAKERAR 101 Query: 174 LQKELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHE 353 LQ EL +REE ++L +N +I Q + L+ E +S + EK+ L+ E Sbjct: 102 LQLELSKVREEFKELKARNTKKEGDLIAAQARLKDLEALLNSKEAALSTALSEKRTLEGE 161 Query: 354 LSHIXNDRGDVERKHFSIKEQIQ 422 L + +E K+Q+Q Sbjct: 162 LHDLRGQVAKLEAALGEAKKQLQ 184
>SMC3_BOVIN (O97594) Structural maintenance of chromosome 3 (Chondroitin| sulfate proteoglycan 6) Length = 1218 Score = 39.7 bits (91), Expect = 0.003 Identities = 28/137 (20%), Positives = 64/137 (46%) Frame = +3 Query: 6 LSVSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKE 185 L +I ++L +A++ LS +++ + EK R L + K +D+E L+ + Sbjct: 223 LEYTIYNQELNETRAKLDELSAKRETSG--EKSRQLRDAQQDARDKMEDIERQVRELKTK 280 Query: 186 LEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHI 365 + ++EE +L + +L+ + L++ E+ R ++E++ L ++ Sbjct: 281 ISAMKEEKEQLSAERQEQIKQRTKLELKAKDLQDELAGNSEQRKRLLKERQKLLEKIEEK 340 Query: 366 XNDRGDVERKHFSIKEQ 416 + + E K S+KE+ Sbjct: 341 QKELAETEPKFNSVKEK 357
>CCD41_HUMAN (Q9Y592) Coiled-coil domain-containing protein 41 (NY-REN-58| antigen) Length = 693 Score = 39.3 bits (90), Expect = 0.004 Identities = 37/140 (26%), Positives = 62/140 (44%), Gaps = 24/140 (17%) Frame = +3 Query: 27 EQLKSMQAEMARLSLEK----------------QLAQVQEKLRLLSLEKHGETSKCKDVE 158 ++LK ++AE+A L EK QLA++Q +R L EK + + Sbjct: 214 QKLKGLEAEVAELKAEKENSEAQVENAQRIQVRQLAEMQATVRSLEAEKQSANLRAE--- 270 Query: 159 ASKLMLQKELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQR------KLE--EEV 314 L+KEL+ E+N L ++ H + I L ++ LK++ + KLE Sbjct: 271 ----RLEKELQSSSEQNTFLINKLHKAEREINTLSSKVKELKHSNKLEITDIKLETARAK 326 Query: 315 SRHVEEKKALQHELSHIXND 374 S E+ +Q EL + +D Sbjct: 327 SELERERNKIQSELDGLQSD 346
>RAD50_PYRAB (Q9UZC8) DNA double-strand break repair rad50 ATPase| Length = 880 Score = 39.3 bits (90), Expect = 0.004 Identities = 37/131 (28%), Positives = 65/131 (49%), Gaps = 8/131 (6%) Frame = +3 Query: 27 EQLKSMQAEMARLSLEKQ--LAQVQEKLRLLSLEKHGETSKCKDVE--ASKLM-LQKELE 191 E LK ++ + L K+ +A+ + L+ + T K ++ +SKL ++ ELE Sbjct: 169 ENLKRIKTNINLLIESKKSFIARTENIEELIKANEDELTKKLSEINEISSKLPPIRGELE 228 Query: 192 MIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEE---EVSRHVEEKKALQHELSH 362 +RE ++L+ S I L+ ++ LK ++ LEE ++ R +EEKKA EL Sbjct: 229 KVRENVKELE----SIKGKISELKIQVEKLKGRKKGLEEKIVQIERSIEEKKAKISELEE 284 Query: 363 IXNDRGDVERK 395 I D ++ K Sbjct: 285 IVKDIPKLQEK 295 Score = 32.0 bits (71), Expect = 0.67 Identities = 30/136 (22%), Positives = 69/136 (50%), Gaps = 4/136 (2%) Frame = +3 Query: 27 EQLKSMQAEMARLSLEKQLAQVQEK---LRLLSLEKHGETSKCKDVEASKLMLQ-KELEM 194 ++L+S++ +++ L ++ + + ++K +++ +E+ E K K E +++ +L+ Sbjct: 235 KELESIKGKISELKIQVEKLKGRKKGLEEKIVQIERSIEEKKAKISELEEIVKDIPKLQE 294 Query: 195 IREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHIXND 374 +E RKL S + RL+ E +S ++ K EEV + E+KK E I Sbjct: 295 KEKEYRKLKGFRDEYESKLRRLEKE-LSKWESELKAIEEVIKEGEKKKERAEE---IREK 350 Query: 375 RGDVERKHFSIKEQIQ 422 ++E++ +K ++ Sbjct: 351 LSEIEKRLEELKPYVE 366
>MYSP_BRUMA (Q01202) Paramyosin| Length = 880 Score = 39.3 bits (90), Expect = 0.004 Identities = 31/130 (23%), Positives = 60/130 (46%), Gaps = 5/130 (3%) Frame = +3 Query: 24 EEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEK-----HGETSKCKDVEASKLMLQKEL 188 E +L + QA++ + E A + L + H E ++A + L++++ Sbjct: 664 ETELSTAQADLDEATKELHAADERANRALADAARAVEQLHEEQEHSMKIDALRKSLEEQV 723 Query: 189 EMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHIX 368 + ++ + RKL + VI +L+ I L+ A L+EE RH E + AL+ + I Sbjct: 724 KQLQVQFRKLKRRLLGGKRVIAKLETRIRDLETA---LDEETRRHKETQGALRKKDRRIK 780 Query: 369 NDRGDVERKH 398 + V+ +H Sbjct: 781 EVQMQVDEEH 790 Score = 36.6 bits (83), Expect = 0.027 Identities = 30/124 (24%), Positives = 54/124 (43%) Frame = +3 Query: 24 EEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIRE 203 EEQ++ M ++++L K Q + ++ ++ LEK T +E +K L+K + ++ Sbjct: 333 EEQIEIMLQKISQLEKAKSRLQSEVEVLIVDLEKAQNTIAI--LERAKEQLEKTVNELKV 390 Query: 204 ENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHIXNDRGD 383 +L + ++ E+ LKN K E+ E K LQ +L D Sbjct: 391 RIDELTVELEAAQREARAALAELQKLKNLYEKAVEQKEALARENKKLQDDLHEAKEALAD 450 Query: 384 VERK 395 RK Sbjct: 451 ANRK 454 Score = 35.4 bits (80), Expect = 0.061 Identities = 29/100 (29%), Positives = 47/100 (47%), Gaps = 2/100 (2%) Frame = +3 Query: 18 IQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMI 197 + EEQ SM+ + R SLE+Q+ Q+Q + R L G K ++ K I Sbjct: 702 LHEEQEHSMKIDALRKSLEEQVKQLQVQFRKLKRRLLG----------GKRVIAKLETRI 751 Query: 198 REENRKLDDQ--NHSSTSVIIRLQDEIISLKNAQRKLEEE 311 R+ LD++ H T +R +D +K Q +++EE Sbjct: 752 RDLETALDEETRRHKETQGALRKKDR--RIKEVQMQVDEE 789 Score = 29.3 bits (64), Expect = 4.3 Identities = 32/130 (24%), Positives = 60/130 (46%), Gaps = 12/130 (9%) Frame = +3 Query: 21 QEEQLKSMQAEMARLS--LEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEM 194 Q E + +AE+ +L LE+ + ++ + +L +KH + C D LQK+ Sbjct: 92 QIESNRKREAELQKLRKLLEESQLENEDAMNILR-KKHQDA--CLDYAEQIEQLQKKNSK 148 Query: 195 IREENRKLDDQNHSSTSVIIRL-QDEIISLKNAQR---------KLEEEVSRHVEEKKAL 344 I E ++L + T+ I +L +D+ ++ K A+R E+++RHV + Sbjct: 149 IDRERQRLQHEVIELTATIDQLKKDKHLAEKAAERFEAQTVELSNKVEDLNRHVNDLAQQ 208 Query: 345 QHELSHIXND 374 + L ND Sbjct: 209 RQRLQAENND 218 Score = 28.9 bits (63), Expect = 5.7 Identities = 21/92 (22%), Positives = 43/92 (46%) Frame = +3 Query: 69 LEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIREENRKLDDQNHSSTSV 248 L +Q ++Q + L E H + + +++ K L ++LE E R+L+D + + Sbjct: 205 LAQQRQRLQAENNDLLKEIHDQKVQLDNLQHVKYQLAQQLE---EARRRLEDAERERSQL 261 Query: 249 IIRLQDEIISLKNAQRKLEEEVSRHVEEKKAL 344 +L + L + + L+EE + E + L Sbjct: 262 QAQLHQVQLELDSVRTALDEESAARAEAEHKL 293
>MYH10_HUMAN (P35580) Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle| myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B) Length = 1976 Score = 39.3 bits (90), Expect = 0.004 Identities = 33/143 (23%), Positives = 70/143 (48%), Gaps = 11/143 (7%) Frame = +3 Query: 24 EEQLKSMQAEMARLSLEKQLAQVQEKLRLL-------SLEKHGETSKCKDVEASKLMLQK 182 ++Q+ +QA++ L L QLA+ +E+L+ +L K+ ++++A LQ+ Sbjct: 1068 QDQIAELQAQIDELKL--QLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQE 1125 Query: 183 ELEMIREENRKLDDQNHSSTSVIIRLQDEI---ISLKNAQRKLEEEVSRHVEE-KKALQH 350 + E + K + Q + + L+ E+ + AQ++L + + V E KKAL+ Sbjct: 1126 DFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEE 1185 Query: 351 ELSHIXNDRGDVERKHFSIKEQI 419 E + D+ ++H + E++ Sbjct: 1186 ETKNHEAQIQDMRQRHATALEEL 1208 Score = 37.4 bits (85), Expect = 0.016 Identities = 30/137 (21%), Positives = 63/137 (45%), Gaps = 7/137 (5%) Frame = +3 Query: 6 LSVSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKE 185 L+ +Q E +AE R L + +++E L H S+ ++ E +LQ E Sbjct: 892 LAEQLQAETELFAEAEEMRARLAAKKQELEEIL-------HDLESRVEEEEERNQILQNE 944 Query: 186 LEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEV-------SRHVEEKKAL 344 + ++ + L++Q +LQ E ++ + +K+EEE+ S+ ++EKK + Sbjct: 945 KKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLM 1004 Query: 345 QHELSHIXNDRGDVERK 395 + ++ + + E K Sbjct: 1005 EDRIAECSSQLAEEEEK 1021 Score = 35.8 bits (81), Expect = 0.046 Identities = 27/96 (28%), Positives = 46/96 (47%) Frame = +3 Query: 27 EQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIREE 206 ++ K M+ +A S QLA+ +EK + L+ ++ + D+E +K + + + Sbjct: 999 KEKKLMEDRIAECS--SQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKA 1056 Query: 207 NRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEV 314 RKLD + I LQ +I LK K EEE+ Sbjct: 1057 KRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEEL 1092 Score = 35.4 bits (80), Expect = 0.061 Identities = 26/147 (17%), Positives = 69/147 (46%), Gaps = 7/147 (4%) Frame = +3 Query: 3 KLSVSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQK 182 +L +++E+ + A ++ +E L ++ ++ + + + + ++A Q+ Sbjct: 1600 ELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQR 1659 Query: 183 ELEMIREENRKLDDQNHSST-------SVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKA 341 ELE R ++ Q+ S + I++LQ+E+ S + A+R E+E +E Sbjct: 1660 ELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITN 1719 Query: 342 LQHELSHIXNDRGDVERKHFSIKEQIQ 422 S + +++ +E + ++E+++ Sbjct: 1720 SASGKSALLDEKRRLEARIAQLEEELE 1746
>IFA1_CAEEL (P90901) Intermediate filament protein ifa-1 (Intermediate filament| protein A1) (IF-A1) (Cel IF A1) Length = 575 Score = 39.3 bits (90), Expect = 0.004 Identities = 32/154 (20%), Positives = 73/154 (47%), Gaps = 10/154 (6%) Frame = +3 Query: 3 KLSVSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDV--------- 155 +L +Q + Q + R+ + Q+ + E++ L E + + + Sbjct: 209 RLLSELQRARTDLDQETLNRIDYQNQVQTLLEEIDFLRRVHDNEIKELQTLASRDTTPEN 268 Query: 156 -EASKLMLQKELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEE 332 E K L + IREE ++++ + + RL+ + I ++A++ +E+ ++ EE Sbjct: 269 REFFKNELSSAIRDIREEYDQVNNVHRNDMESWYRLKVQEIQTQSARQNMEQGYAK--EE 326 Query: 333 KKALQHELSHIXNDRGDVERKHFSIKEQIQAVNF 434 K L+ +LS + D+E ++ +++QIQ +N+ Sbjct: 327 VKRLRTQLSDLRGKLADLESRNSLLEKQIQELNY 360 Score = 34.7 bits (78), Expect = 0.10 Identities = 32/110 (29%), Positives = 49/110 (44%), Gaps = 11/110 (10%) Frame = +3 Query: 132 ETSKC-KDVEASKLMLQKELEMIREENRKLDD------QNHSSTSVII----RLQDEIIS 278 ET+K KD+E +Q EL +R RKL+D Q+ + ++ L+ EI Sbjct: 132 ETNKQRKDMEGQLKKMQDELAEMR---RKLEDATKGREQDRAKIDALLVTLSNLEAEISL 188 Query: 279 LKNAQRKLEEEVSRHVEEKKALQHELSHIXNDRGDVERKHFSIKEQIQAV 428 LK +LE+EV R +E + L EL D + Q+Q + Sbjct: 189 LKRRIAQLEDEVKRIKQENQRLLSELQRARTDLDQETLNRIDYQNQVQTL 238
>CYTSA_PANTR (Q2KNA1) Cytospin-A| Length = 1117 Score = 39.3 bits (90), Expect = 0.004 Identities = 32/145 (22%), Positives = 73/145 (50%), Gaps = 6/145 (4%) Frame = +3 Query: 6 LSVSIQEEQ--LKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQ 179 L+ +++E + + S Q EM RL + + + Q+ L S+ G+ S +D+ S + + Sbjct: 558 LAATLEEYKATVASDQIEMNRLKAQLE-NEKQKVAELYSIHNSGDKSDIQDLLESVRLDK 616 Query: 180 KELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEE----KKALQ 347 ++ E + + +D H+ RLQD I +++ R +EE + +E+ + L+ Sbjct: 617 EKAETLASSLQ--EDLAHTRNDAN-RLQDAIAKVEDEYRAFQEEAKKQIEDLNMTLEKLR 673 Query: 348 HELSHIXNDRGDVERKHFSIKEQIQ 422 +L +R D++ F ++++++ Sbjct: 674 SDLDEKETERSDMKETIFELEDEVE 698 Score = 28.9 bits (63), Expect = 5.7 Identities = 20/67 (29%), Positives = 37/67 (55%) Frame = +3 Query: 30 QLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIREEN 209 +L+ M+A+ L + + ++ EK ++ H T DVE++ L LQ++ IREE Sbjct: 205 ELRDMRAQ---LGINEDHSEGDEKSEKETIMAHQPT----DVESTLLQLQEQNTAIREEL 257 Query: 210 RKLDDQN 230 +L ++N Sbjct: 258 NQLKNEN 264
>CYTSA_HUMAN (Q69YQ0) Cytospin-A (NY-REN-22 antigen)| Length = 1117 Score = 39.3 bits (90), Expect = 0.004 Identities = 32/145 (22%), Positives = 73/145 (50%), Gaps = 6/145 (4%) Frame = +3 Query: 6 LSVSIQEEQ--LKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQ 179 L+ +++E + + S Q EM RL + + + Q+ L S+ G+ S +D+ S + + Sbjct: 558 LAATLEEYKATVASDQIEMNRLKAQLE-NEKQKVAELYSIHNSGDKSDIQDLLESVRLDK 616 Query: 180 KELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEE----KKALQ 347 ++ E + + +D H+ RLQD I +++ R +EE + +E+ + L+ Sbjct: 617 EKAETLASSLQ--EDLAHTRNDAN-RLQDAIAKVEDEYRAFQEEAKKQIEDLNMTLEKLR 673 Query: 348 HELSHIXNDRGDVERKHFSIKEQIQ 422 +L +R D++ F ++++++ Sbjct: 674 SDLDEKETERSDMKETIFELEDEVE 698 Score = 28.9 bits (63), Expect = 5.7 Identities = 20/67 (29%), Positives = 37/67 (55%) Frame = +3 Query: 30 QLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIREEN 209 +L+ M+A+ L + + ++ EK ++ H T DVE++ L LQ++ IREE Sbjct: 205 ELRDMRAQ---LGINEDHSEGDEKSEKETIMAHQPT----DVESTLLQLQEQNTAIREEL 257 Query: 210 RKLDDQN 230 +L ++N Sbjct: 258 NQLKNEN 264
>RAD50_AQUAE (O67124) Probable DNA double-strand break repair rad50 ATPase| Length = 978 Score = 39.3 bits (90), Expect = 0.004 Identities = 42/165 (25%), Positives = 77/165 (46%), Gaps = 32/165 (19%) Frame = +3 Query: 24 EEQLKSMQAEMARL-----------SLEKQLAQVQEKLRLL-SLEKHGETSKCKDVEASK 167 EE+LK ++ +L SLE++L+QV KL+ L +LEK E + K + K Sbjct: 213 EEELKELKETEEKLRQELKKAEEKDSLERELSQVVTKLKELENLEKEVEKLREKLEFSRK 272 Query: 168 LM----LQKELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEK 335 + + K +E I ++ +L + + T + L+DE+ + ++E E + EEK Sbjct: 273 VAPYVPIAKRIEEIDKKLTELKVRKNKLTKELAVLKDELSFAQEELNRIEAEKEKFKEEK 332 Query: 336 ---KALQH-------------ELSHIXNDRGDVERKHFSIKEQIQ 422 K L+H ELS + + + ER++ K++ + Sbjct: 333 EREKELEHRLKKLQEIKEILKELSQLSSSLKEKEREYEQAKQEFE 377 Score = 38.9 bits (89), Expect = 0.005 Identities = 27/113 (23%), Positives = 56/113 (49%) Frame = +3 Query: 96 EKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIREENRKLDDQNHSSTSVIIRLQDEII 275 EK+R L+ E K++E + L+KE E++++ + + L++E+ Sbjct: 167 EKVRQLASETF------KNLEGKREALKKEYELLKDYT---PTKKEVLEKTLKNLEEELK 217 Query: 276 SLKNAQRKLEEEVSRHVEEKKALQHELSHIXNDRGDVERKHFSIKEQIQAVNF 434 LK + KL +E+ + EEK +L+ ELS + ++E +++ + + F Sbjct: 218 ELKETEEKLRQELKK-AEEKDSLERELSQVVTKLKELENLEKEVEKLREKLEF 269 Score = 32.7 bits (73), Expect = 0.39 Identities = 27/136 (19%), Positives = 61/136 (44%), Gaps = 2/136 (1%) Frame = +3 Query: 27 EQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIREE 206 E LK ++ L +EK+ +++ KL + ++ +A Q ELE+++E+ Sbjct: 557 ENLKERIKKLEELRIEKE--KLEHKLNKYRKALEDRQKQKEEAQAKLHKAQTELELLKEK 614 Query: 207 NRKLDD--QNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHIXNDRG 380 R+ + + RL+D SLK + ++ E++K L+ + + + Sbjct: 615 IREKSRLVKEFKELYRVERLEDYEESLKEEINYINSKLQEIEEKEKKLRKHFEELSSRKS 674 Query: 381 DVERKHFSIKEQIQAV 428 +E + ++ E I ++ Sbjct: 675 KLEGELSALNESINSL 690
>AKAP9_HUMAN (Q99996) A-kinase anchor protein 9 (Protein kinase A-anchoring| protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Hyperion protein) (Yotiao protei Length = 3911 Score = 39.3 bits (90), Expect = 0.004 Identities = 27/108 (25%), Positives = 59/108 (54%), Gaps = 9/108 (8%) Frame = +3 Query: 9 SVSIQEEQLKSMQAEMARLSLE-----KQLAQVQEKLRLLSLEKHGETSKCKDV----EA 161 ++++ E+Q+K M + L+++ Q +++E+L L+ EK + +D+ Sbjct: 492 NITVNEDQIKLMNVAINELNIKLQDTNSQKEKLKEELGLILEEKCALQRQLEDLVEELSF 551 Query: 162 SKLMLQKELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLE 305 S+ +Q+ + I E+ KL++ H S S + L+ EI+S ++++LE Sbjct: 552 SREQIQRARQTIAEQESKLNEA-HKSLSTVEDLKAEIVSASESRKELE 598 Score = 34.7 bits (78), Expect = 0.10 Identities = 27/132 (20%), Positives = 64/132 (48%), Gaps = 7/132 (5%) Frame = +3 Query: 24 EEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKL-----MLQKEL 188 E++L + L E+Q Q+QE+ LLS +K ++ VE L +++++L Sbjct: 1961 EQELLCASNRLQELEAEQQ--QIQEERELLSRQKEAMKAEAGPVEQQLLQETEKLMKEKL 2018 Query: 189 EMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHIX 368 E+ + + DD ++ I +++++ +++ E+ ++ +AL+ +L + Sbjct: 2019 EVQCQAEKVRDDLQKQVKALEIDVEEQVSRFIELEQEKNTELMDLRQQNQALEKQLEKMR 2078 Query: 369 N--DRGDVERKH 398 D ++R+H Sbjct: 2079 KFLDEQAIDREH 2090 Score = 34.7 bits (78), Expect = 0.10 Identities = 35/141 (24%), Positives = 68/141 (48%), Gaps = 5/141 (3%) Frame = +3 Query: 24 EEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIRE 203 + +L+ ++AE+ + +Q+ Q++++L + + E E + + E Sbjct: 439 QRKLEQLRAELDEM-YGQQIVQMKQELIRQHMAQMEEMKTRHKGEMENALRSYSNITVNE 497 Query: 204 ENRKLDDQNHSSTSVIIRLQDEIISLKNAQR-KLEEEVSRHVEEKKALQHELSHIXND-- 374 + KL N + + I+LQD N+Q+ KL+EE+ +EEK ALQ +L + + Sbjct: 498 DQIKL--MNVAINELNIKLQDT-----NSQKEKLKEELGLILEEKCALQRQLEDLVEELS 550 Query: 375 --RGDVERKHFSIKEQIQAVN 431 R ++R +I EQ +N Sbjct: 551 FSREQIQRARQTIAEQESKLN 571 Score = 32.7 bits (73), Expect = 0.39 Identities = 35/159 (22%), Positives = 73/159 (45%), Gaps = 16/159 (10%) Frame = +3 Query: 3 KLSVSIQEEQLKS----MQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDV----- 155 +L + E+Q+K +Q + A+L E + + ++K L+ H S+ + + Sbjct: 761 QLKTELLEKQMKEKENDLQEKFAQLEAENSILKDEKKTLEDMLKIHTPVSQEERLIFLDS 820 Query: 156 ---EASKLMLQKELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHV 326 ++ + +KE+E++ EEN L Q I+L +EI +N E+ + Sbjct: 821 IKSKSKDSVWEKEIEILIEENEDLKQQ-------CIQLNEEIEKQRNTFSFAEKNFEVNY 873 Query: 327 EEKKALQHELSHIXNDRGDVE----RKHFSIKEQIQAVN 431 +E LQ E + + + D+E ++ K +++A+N Sbjct: 874 QE---LQEEYACLLKVKDDLEDSKNKQELEYKSKLKALN 909 Score = 32.7 bits (73), Expect = 0.39 Identities = 24/109 (22%), Positives = 54/109 (49%) Frame = +3 Query: 27 EQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIREE 206 +++++MQ E L + KQ + E +L L++ SK +++ LQKE+E++R+E Sbjct: 688 QKIETMQFEKDNL-ITKQNQLILEISKLKDLQQSLVNSKSEEMTLQINELQKEIEILRQE 746 Query: 207 NRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHE 353 ++ + ++ + +K + L+E+ ++ E L+ E Sbjct: 747 EKEKGTLEQEVQELQLKTELLEKQMKEKENDLQEKFAQLEAENSILKDE 795
>MYSP_SCHMA (P06198) Paramyosin| Length = 866 Score = 39.3 bits (90), Expect = 0.004 Identities = 38/146 (26%), Positives = 72/146 (49%), Gaps = 10/146 (6%) Frame = +3 Query: 3 KLSVSIQEEQLKSMQAEMARLSLEKQLAQ-VQEKLRLLSLEKHGETSKCKD--VEASKLM 173 +L + I+E +K +AE + +++ Q +Q ++R L E GE+ +CKD +A K Sbjct: 702 QLEIEIREITVKLEEAEASATREGRRMVQKLQARVRELESEFDGESRRCKDALAQARKFE 761 Query: 174 LQ-KELEMIREENRKLDDQNHSSTSVIIRLQDEI----ISLKNAQRKLE--EEVSRHVEE 332 Q KEL+ E++R++ ++ LQD + + +K +R+LE EEVS+ Sbjct: 762 RQYKELQTQAEDDRRM----------VLELQDLLDKTQMKMKAYKRQLEEMEEVSQITMN 811 Query: 333 KKALQHELSHIXNDRGDVERKHFSIK 410 K + R D+ + +++ Sbjct: 812 KYRKAQQQIEEAEHRADMAERTVTVR 837 Score = 30.8 bits (68), Expect = 1.5 Identities = 25/113 (22%), Positives = 52/113 (46%), Gaps = 19/113 (16%) Frame = +3 Query: 30 QLKSMQAEMARLSLEKQ------------LAQVQEKLRLLSLEKHGETSKCKDVEASKLM 173 ++K +Q+E+ LSLE + +Q ++ L++E + TS+ +E+ L Sbjct: 340 EIKDLQSEIESLSLENSELIRRAKAAESLASDLQRRVDELTIEVNTLTSQNSQLESENLR 399 Query: 174 LQKELE-------MIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEE 311 L+ + ++ ENR+++DQ S + + L+ + +LE E Sbjct: 400 LKSLVNDLTDKNNLLERENRQMNDQVKELKSSLRDANRRLTDLEALRSQLEAE 452
>RAD50_PYRFU (P58301) DNA double-strand break repair rad50 ATPase| Length = 882 Score = 39.3 bits (90), Expect = 0.004 Identities = 34/149 (22%), Positives = 73/149 (48%), Gaps = 17/149 (11%) Frame = +3 Query: 27 EQLKSMQAEMARL-----SLEKQLAQVQEKLRLLSLEKHGET-SKCKDVEA------SKL 170 ++L ++ ++A L LEK+L ++ KL + + SK +++E + L Sbjct: 552 KKLAPLEKKLAALIHKKQELEKELKELNTKLESFGFKSVEDLDSKLRELEEIYKRYLTLL 611 Query: 171 MLQKELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKL-----EEEVSRHVEEK 335 +KELE+ + E K + S + ++ +I ++ +L EEE + EEK Sbjct: 612 NSKKELEITQREIAKAKETLEMSFEELAEVEADIERIEKKLSQLKQKYNEEEYKKKREEK 671 Query: 336 KALQHELSHIXNDRGDVERKHFSIKEQIQ 422 + L+ EL+ + + ++E++ +IK ++ Sbjct: 672 EELEKELARLEAQKKELEKRRDTIKSTLE 700
>SYCP1_MOUSE (Q62209) Synaptonemal complex protein 1 (SCP-1)| Length = 993 Score = 39.3 bits (90), Expect = 0.004 Identities = 36/119 (30%), Positives = 61/119 (51%), Gaps = 8/119 (6%) Frame = +3 Query: 27 EQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQ--------K 182 E+L+ +QAE ARL + +L + EK++ L E E + K+ + S+L++Q K Sbjct: 223 EELR-VQAENARLEMHFKLKEDHEKIQHLEEEYQKEVNN-KENQVSELLIQSAEKENKMK 280 Query: 183 ELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELS 359 +L + EE+R +Q T +LQDE +LK K + S + K ++Q +S Sbjct: 281 DLTFLLEESRDKANQLEEKT----KLQDE--NLKELSEKKDHLTSELEDIKMSMQRSMS 333 Score = 32.0 bits (71), Expect = 0.67 Identities = 26/140 (18%), Positives = 65/140 (46%), Gaps = 7/140 (5%) Frame = +3 Query: 24 EEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIRE 203 E + K ++E S+E ++ + ++++++L SKC +++ K +E + + Sbjct: 586 EVKCKLDKSEENARSIECEVLKKEKQMKILE-------SKCNNLKKQVENKSKNIEELHQ 638 Query: 204 ENRKLDDQNHSSTS-------VIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSH 362 EN+ L ++ + + +L+ E+ S K ++ + +E KK + +L Sbjct: 639 ENKTLKKKSSAEIKQLNAYEIKVSKLELELESTKQRFEEMTNNYQKEIENKKISEGKL-- 696 Query: 363 IXNDRGDVERKHFSIKEQIQ 422 G+VE+ ++ E ++ Sbjct: 697 ----LGEVEKAKATVDEAVK 712
>CYTSA_CHICK (Q2KN97) Cytospin-A| Length = 1118 Score = 39.3 bits (90), Expect = 0.004 Identities = 30/132 (22%), Positives = 65/132 (49%), Gaps = 4/132 (3%) Frame = +3 Query: 39 SMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIREENRKL 218 S Q EM RL + + + Q+ L S+ G+ S +D+ S + +++ E + L Sbjct: 572 SDQIEMNRLKAQLE-HEKQKVAELYSIHNSGDKSDIQDLLESVRLDKEKAETLASS---L 627 Query: 219 DDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEE----KKALQHELSHIXNDRGDV 386 ++ + + RLQD I +++ R +EE + +E+ + L+ EL +R D+ Sbjct: 628 QEELAHTRNDANRLQDAIAKVEDEYRVFQEEAKKQIEDLNVTLEKLRAELDEKETERSDM 687 Query: 387 ERKHFSIKEQIQ 422 + F ++++++ Sbjct: 688 KETIFELEDEVE 699
>LMNA_RAT (P48679) Lamin-A| Length = 665 Score = 38.9 bits (89), Expect = 0.005 Identities = 32/143 (22%), Positives = 66/143 (46%), Gaps = 6/143 (4%) Frame = +3 Query: 12 VSIQEEQLKSMQAEMARLSL-----EKQLAQVQEKLRLLSLEKHGETSKCKD-VEASKLM 173 +++ ++++S++ E A L L E+ +++ ++ + G+ K D V + Sbjct: 42 LAVYIDRVRSLETENAGLRLRITESEEVVSREVSGIKAAYEAELGDARKTLDSVAKERAR 101 Query: 174 LQKELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHE 353 LQ EL +REE ++L +N ++ Q + L+ E +S + EK+ L+ E Sbjct: 102 LQLELSKVREEFKELKARNTKKEGDLLAAQARLKDLEALLNSKEAALSTALSEKRTLEGE 161 Query: 354 LSHIXNDRGDVERKHFSIKEQIQ 422 L + +E K+Q+Q Sbjct: 162 LHDLRGQVAKLEAALGEAKKQLQ 184
>LMNA_MOUSE (P48678) Lamin-A/C| Length = 665 Score = 38.9 bits (89), Expect = 0.005 Identities = 32/143 (22%), Positives = 66/143 (46%), Gaps = 6/143 (4%) Frame = +3 Query: 12 VSIQEEQLKSMQAEMARLSL-----EKQLAQVQEKLRLLSLEKHGETSKCKD-VEASKLM 173 +++ ++++S++ E A L L E+ +++ ++ + G+ K D V + Sbjct: 42 LAVYIDRVRSLETENAGLRLRITESEEVVSREVSGIKAAYEAELGDARKTLDSVAKERAR 101 Query: 174 LQKELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHE 353 LQ EL +REE ++L +N ++ Q + L+ E +S + EK+ L+ E Sbjct: 102 LQLELSKVREEFKELKARNTKKEGDLLAAQARLKDLEALLNSKEAALSTALSEKRTLEGE 161 Query: 354 LSHIXNDRGDVERKHFSIKEQIQ 422 L + +E K+Q+Q Sbjct: 162 LHDLRGQVAKLEAALGEAKKQLQ 184
>MYSS_CYPCA (Q90339) Myosin heavy chain, fast skeletal muscle| Length = 1935 Score = 38.9 bits (89), Expect = 0.005 Identities = 34/135 (25%), Positives = 60/135 (44%), Gaps = 8/135 (5%) Frame = +3 Query: 6 LSVSIQEEQLKSMQAE-MARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQK 182 L V++++ Q + +AE +A +KQL +++ ++R L E E + D K Sbjct: 1787 LEVTVKDLQHRLDEAESLAMKGGKKQLQKLESRVRELEAEVEAEQRRGADAV-------K 1839 Query: 183 ELEMIREENRKLDDQNHSSTSVIIRLQDEIISL-------KNAQRKLEEEVSRHVEEKKA 341 + ++L Q +IRLQD + L K + EE+ + H+ + Sbjct: 1840 GVRKYERRVKELTYQTEEDKKNVIRLQDLVDKLQLKVKVYKRQAEEAEEQTNTHLSRYRK 1899 Query: 342 LQHELSHIXNDRGDV 386 +QHEL +R DV Sbjct: 1900 VQHELEE-AQERADV 1913 Score = 37.7 bits (86), Expect = 0.012 Identities = 31/134 (23%), Positives = 66/134 (49%), Gaps = 3/134 (2%) Frame = +3 Query: 36 KSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIREENRK 215 K ++ +M L EK Q+Q +L E +C+ + SK+ L+ +L +E N + Sbjct: 872 KELEEKMVSLLQEKNDLQLQVTAESENLSDAEE--RCEGLIKSKIQLEAKL---KETNER 926 Query: 216 LDDQ---NHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHIXNDRGDV 386 L+D+ N T+ +L+DE LK LE +++ +EK A ++++ ++ + Sbjct: 927 LEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMASQ 986 Query: 387 ERKHFSIKEQIQAV 428 + + ++ +A+ Sbjct: 987 DESIAKLTKEKKAL 1000 Score = 34.3 bits (77), Expect = 0.13 Identities = 28/124 (22%), Positives = 59/124 (47%), Gaps = 1/124 (0%) Frame = +3 Query: 57 ARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIREENRKLDDQNHS 236 A+ +LEK ++++L + + + D+ A + LQ E E +R+L+++ Sbjct: 1242 AKANLEKMCRTLEDQLSEIKTKSDENVRQLNDMNAQRARLQTENG---EFSRQLEEKE-- 1296 Query: 237 STSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSH-IXNDRGDVERKHFSIKE 413 L ++ K A + EE+ RH+EE+ ++ L+H + + R D + +E Sbjct: 1297 ------ALVSQLTRGKQAYTQQIEELKRHIEEEVKAKNALAHAVQSARHDCDLLREQYEE 1350 Query: 414 QIQA 425 + +A Sbjct: 1351 EQEA 1354 Score = 32.0 bits (71), Expect = 0.67 Identities = 27/103 (26%), Positives = 51/103 (49%) Frame = +3 Query: 24 EEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIRE 203 E LK Q + L EKQ Q EK++ E SK +D ++ LQK+++ ++ Sbjct: 1057 EGDLKLAQESIMDLENEKQ--QSDEKIKKKDFEISQLLSKIEDEQSLGAQLQKKIKELQA 1114 Query: 204 ENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEE 332 +L+++ + + +++ + L R+L EE+S +EE Sbjct: 1115 RIEELEEEIEAERAARAKVEKQRADL---SREL-EEISERLEE 1153
>ITSN1_HUMAN (Q15811) Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17)| Length = 1721 Score = 38.9 bits (89), Expect = 0.005 Identities = 34/132 (25%), Positives = 60/132 (45%), Gaps = 7/132 (5%) Frame = +3 Query: 21 QEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIR 200 ++EQ + Q E A +++ Q QE+ R L LEK +L Q+ELE R Sbjct: 377 RKEQERLAQLERAEQERKERERQEQERKRQLELEK-------------QLEKQRELERQR 423 Query: 201 EENRKLDDQNHSSTSVIIRLQDEI-------ISLKNAQRKLEEEVSRHVEEKKALQHELS 359 EE R+ + + + + Q ++ L N + K +E++ +KK L+ EL Sbjct: 424 EEERRKEIERREAAKRELERQRQLEWERNRRQELLNQRNKEQEDIVVLKAKKKTLEFELE 483 Query: 360 HIXNDRGDVERK 395 + + + +E K Sbjct: 484 ALNDKKHQLEGK 495
>MYSS_RABIT (P02562) Myosin heavy chain, skeletal muscle (Fragments)| Length = 1084 Score = 38.5 bits (88), Expect = 0.007 Identities = 37/134 (27%), Positives = 69/134 (51%), Gaps = 13/134 (9%) Frame = +3 Query: 24 EEQLKSMQA---EMARLSLEKQLAQVQE-KLRLLSLEKHGETSKCKDVEASKLMLQ---- 179 E+ +K +Q E +L+L+ Q+Q+ + R+ LE E+ + ++VEA K + + Sbjct: 936 EQTVKDLQQRLDEAEQLALKGGKKQIQKLEARVKELENEVESEQKRNVEAVKGLRKHERR 995 Query: 180 -KELEMIREENRK----LDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKAL 344 KEL EE+RK L D ++ +LQ ++ + K + EE+ + ++ + + L Sbjct: 996 VKELTYQTEEDRKNVLRLQD-------LVDKLQSKVKAYKRQAEEAEEQSNINLSKFRKL 1048 Query: 345 QHELSHIXNDRGDV 386 QHEL +R D+ Sbjct: 1049 QHELEE-AEERADI 1061 Score = 34.7 bits (78), Expect = 0.10 Identities = 24/132 (18%), Positives = 62/132 (46%), Gaps = 3/132 (2%) Frame = +3 Query: 45 QAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEM---IREENRK 215 +AE R LE+++ + ++ L L+ E D E + +++ ++++ I+E + Sbjct: 24 KAEAKRKELEEKMVALMQEKNDLQLQVQAEADSLADAEERQDLIKTKIQLEAKIKEVTER 83 Query: 216 LDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHIXNDRGDVERK 395 +D+ + + + +RKLE+E S ++ L+ L+ + ++ E K Sbjct: 84 AEDEEEINAELTAK-----------KRKLEDECSELKKDIDDLELTLAKVEKEKHATENK 132 Query: 396 HFSIKEQIQAVN 431 ++ E++ ++ Sbjct: 133 VKNLTEEMAGLD 144 Score = 32.3 bits (72), Expect = 0.51 Identities = 29/130 (22%), Positives = 60/130 (46%), Gaps = 7/130 (5%) Frame = +3 Query: 6 LSVSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGE-------TSKCKDVEAS 164 L + +Q E AE R L K Q++ K++ ++ E T+K + +E Sbjct: 46 LQLQVQAEADSLADAE-ERQDLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDE 104 Query: 165 KLMLQKELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKAL 344 L+K+++ + K++ + H++ + + L +E+ L +E +++ +EKKAL Sbjct: 105 CSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGL-------DETIAKLTKEKKAL 157 Query: 345 QHELSHIXND 374 Q +D Sbjct: 158 QEAHQQTLDD 167
>RB6I2_MOUSE (Q99MI1) RAB6-interacting protein 2 (ERC protein 1) (ERC1)| (CAZ-associated structural protein 2) (CAST2) Length = 1120 Score = 38.5 bits (88), Expect = 0.007 Identities = 31/138 (22%), Positives = 63/138 (45%) Frame = +3 Query: 12 VSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELE 191 + +++ ++ SM+ + LE+++ ++ L S E+ E + + + ++ ++E Sbjct: 384 IEMKDSKISSMERGLR--DLEEEIQMLKSNGALSSEEREEEMKQMEVYRSHSKFMKNKVE 441 Query: 192 MIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHIXN 371 ++EE D Q LQ EI +K +E+SR E ALQ +L + N Sbjct: 442 QLKEELSSKDAQGEELKKRAAGLQSEIGQVK-------QELSRKDTELLALQTKLETLTN 494 Query: 372 DRGDVERKHFSIKEQIQA 425 D ++ +KE + A Sbjct: 495 QFSDSKQHIEVLKESLTA 512 Score = 32.7 bits (73), Expect = 0.39 Identities = 39/179 (21%), Positives = 78/179 (43%), Gaps = 37/179 (20%) Frame = +3 Query: 3 KLSVSIQEEQLKSMQAEM--ARLSLEKQLAQVQEKLRLL---SLEKH---GETSKCKDV- 155 K S++ +E++ +Q E+ RL LE++ + +K + + + EK GE KD+ Sbjct: 507 KESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDML 566 Query: 156 ---EASKLMLQKELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNA------------ 290 E +LQK++E ++E+ R + Q S + LQ + + A Sbjct: 567 DVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALADKE 626 Query: 291 -------------QRKLEEEVSRHVEEKKALQHELSHIXNDRGDVERKHFSIKEQIQAV 428 +R+ +EE+ + ++ K L+ ++S + D + E IKE ++ Sbjct: 627 RTIERLKEQRDRDEREKQEEIDTYKKDLKDLREKVSLLQGDLSEKEASLLDIKEHASSL 685 Score = 29.6 bits (65), Expect = 3.3 Identities = 31/126 (24%), Positives = 54/126 (42%), Gaps = 15/126 (11%) Frame = +3 Query: 66 SLEKQLAQVQEK--LRLLSLEKHGETSKCKDVEASKLMLQKELEMIREENRKLDDQNH-- 233 S++K L +Q K + E H T + + E L+ LE +EN L ++ H Sbjct: 308 SIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHHLESLLEQKEKENNMLREEMHRR 367 Query: 234 ----------SSTSVIIRLQD-EIISLKNAQRKLEEEVSRHVEEKKALQHELSHIXNDRG 380 + +I ++D +I S++ R LEEE+ + ++ AL E + Sbjct: 368 FENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEI-QMLKSNGALSSEEREEEMKQM 426 Query: 381 DVERKH 398 +V R H Sbjct: 427 EVYRSH 432
>EP15_HUMAN (P42566) Epidermal growth factor receptor substrate 15 (Protein| Eps15) (AF-1p protein) Length = 896 Score = 38.5 bits (88), Expect = 0.007 Identities = 31/139 (22%), Positives = 60/139 (43%) Frame = +3 Query: 6 LSVSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKE 185 L+ I + Q + E E + Q +++ L E E + + ++A K +Q+ Sbjct: 338 LNNEIVDLQREKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQEL 397 Query: 186 LEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHI 365 L+ + E+ +L++Q I SLK E ++S + EE + ELS + Sbjct: 398 LDELDEQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRL 457 Query: 366 XNDRGDVERKHFSIKEQIQ 422 + ++E S K Q++ Sbjct: 458 QQETAELEESVESGKAQLE 476 Score = 29.6 bits (65), Expect = 3.3 Identities = 27/135 (20%), Positives = 57/135 (42%) Frame = +3 Query: 9 SVSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKEL 188 + ++Q+ Q + Q + L++Q AQ++E+L+ + + E ++A + ++ Sbjct: 381 NTNLQKLQAQKQQVQELLDELDEQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQI 440 Query: 189 EMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHIX 368 EE K ++ + RLQ E +LEE V + + LQ L Sbjct: 441 STYEEELAKAREE-------LSRLQQET-------AELEESVESGKAQLEPLQQHLQDSQ 486 Query: 369 NDRGDVERKHFSIKE 413 + ++ K +K+ Sbjct: 487 QEISSMQMKLMEMKD 501
>DYNA_DROME (P13496) 150 kDa dynein-associated polypeptide (DP-150) (DAP-150)| (Protein glued) Length = 1265 Score = 38.5 bits (88), Expect = 0.007 Identities = 27/134 (20%), Positives = 61/134 (45%) Frame = +3 Query: 24 EEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIRE 203 E+++ ++A+ L+ QLA + EKL L ++ + + ++ + K+ + E ++E Sbjct: 217 EDKVALLEAQKTSAELQAQLADLTEKLETLKQRRNEDKERLREFDKMKI----QFEQLQE 272 Query: 204 ENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHIXNDRGD 383 K+ S LQ E++ K + E +H +E L + I D+ Sbjct: 273 FRTKIMGAQAS-------LQKELLRAKQEAKDAIEAKEQHAQEMADLADNVEMITLDKEM 325 Query: 384 VERKHFSIKEQIQA 425 E K +++ ++++ Sbjct: 326 AEEKADTLQLELES 339
>MYS2_DICDI (P08799) Myosin-2 heavy chain, non muscle (Myosin II heavy chain, non| muscle) Length = 2116 Score = 38.5 bits (88), Expect = 0.007 Identities = 35/159 (22%), Positives = 75/159 (47%), Gaps = 17/159 (10%) Frame = +3 Query: 3 KLSVSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQK 182 +L + +++ + + + ++A +L+ Q V+EK+R L E E +E K ++ Sbjct: 895 ELEIRVEDMESELDEKKLALENLQNQKRSVEEKVRDLEEELQEEQKLRNTLEKLKKKYEE 954 Query: 183 ELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKK-------- 338 EL EE ++++D + S + +++DE+ Q+++EE EE K Sbjct: 955 EL----EEMKRVNDGQSDTISRLEKIKDEL------QKEVEELTESFSEESKDKGVLEKT 1004 Query: 339 --ALQHELSHI-------XNDRGDVERKHFSIKEQIQAV 428 LQ EL + D+ ++ R+ ++E+++ V Sbjct: 1005 RVRLQSELDDLTVRLDSETKDKSELLRQKKKLEEELKQV 1043 Score = 37.4 bits (85), Expect = 0.016 Identities = 28/128 (21%), Positives = 53/128 (41%) Frame = +3 Query: 6 LSVSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKE 185 L + ++ EQ E RL LE +L V E+L +K E K+ L+KE Sbjct: 1267 LKLELEAEQKAKQALEKKRLGLESELKHVNEQLEEEKKQKESN-------EKRKVDLEKE 1319 Query: 186 LEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHI 365 + ++++ + + T + + E+ +K + + VE+ K LQ + + Sbjct: 1320 VSELKDQIEEEVASKKAVTEAKNKKESELDEIKRQYADVVSSRDKSVEQLKTLQAKNEEL 1379 Query: 366 XNDRGDVE 389 N + E Sbjct: 1380 RNTAEEAE 1387 Score = 37.0 bits (84), Expect = 0.021 Identities = 38/170 (22%), Positives = 73/170 (42%), Gaps = 31/170 (18%) Frame = +3 Query: 6 LSVSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKE 185 L I++E M+ E + +LE +L +++E + + E SK + E SK +++ E Sbjct: 1879 LRAQIEDEGKIKMRLEKEKRALEGELEELRETV------EEAEDSK-SEAEQSKRLVELE 1931 Query: 186 LEMIREENRKLDDQNHSSTSVIIRLQDEIISLK--------------NAQRKLEEEV--- 314 LE R +K D + LQ EI+ K ++++LE E+ Sbjct: 1932 LEDARRNLQKEIDAKEIAEDAKSNLQREIVEAKGRLEEESIARTNSDRSRKRLEAEIDAL 1991 Query: 315 -----------SRHVEEKKALQHELSHIXNDRGDVER---KHFSIKEQIQ 422 ++ ++E K ++ EL G+ E+ K F + E+++ Sbjct: 1992 TAQVDAEQKAKNQQIKENKKIETELKEYRKKFGESEKTKTKEFLVVEKLE 2041 Score = 36.2 bits (82), Expect = 0.035 Identities = 32/121 (26%), Positives = 66/121 (54%), Gaps = 3/121 (2%) Frame = +3 Query: 3 KLSVSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQK 182 +L +++EQ K+ QA+ ++ +LE ++ ++ ++ E G+ +E K L+ Sbjct: 1850 ELRSKLEQEQAKATQADKSKKTLEGEIDNLRAQI-----EDEGKIKM--RLEKEKRALEG 1902 Query: 183 ELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEV-SRHVEE--KKALQHE 353 ELE +RE + +D + S RL + + L++A+R L++E+ ++ + E K LQ E Sbjct: 1903 ELEELRETVEEAED-SKSEAEQSKRLVE--LELEDARRNLQKEIDAKEIAEDAKSNLQRE 1959 Query: 354 L 356 + Sbjct: 1960 I 1960 Score = 32.3 bits (72), Expect = 0.51 Identities = 29/119 (24%), Positives = 56/119 (47%), Gaps = 7/119 (5%) Frame = +3 Query: 18 IQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMI 197 +++E L + A+ +LE +L +V+++L E ++E SK L E+E I Sbjct: 1687 LEDEILAKDKLVKAKRALEVELEEVRDQLE-------EEEDSRSELEDSKRRLTTEVEDI 1739 Query: 198 R-------EENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHE 353 + E+N KLD+ +L D++ +LK +++++ KK L+ E Sbjct: 1740 KKKYDAEVEQNTKLDEAKK-------KLTDDVDTLKKQLEDEKKKLNESERAKKRLESE 1791
>NIN_MOUSE (Q61043) Ninein| Length = 2035 Score = 38.5 bits (88), Expect = 0.007 Identities = 36/130 (27%), Positives = 60/130 (46%), Gaps = 16/130 (12%) Frame = +3 Query: 3 KLSVSIQEEQLKSMQAEMARLSLEKQ-----LAQVQEKLRLLSLEKHGETSK-----CKD 152 K +S EQL ++A+ R S KQ ++ +++KL++L E+ E S +D Sbjct: 1185 KSQISQLREQLTVLRADCDRASERKQDLLFDISVLKKKLKML--ERLPEASSRYKVLYED 1242 Query: 153 VEASKLMLQKELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQ------RKLEEEV 314 LQ+EL ++ + D N T+ + RLQDE+ ++ K +EV Sbjct: 1243 AARENSCLQEELRLVETRYEESLDSNKELTAEVYRLQDEMKKMEEVMETFLSLEKSYDEV 1302 Query: 315 SRHVEEKKAL 344 EE +AL Sbjct: 1303 KVENEELRAL 1312 Score = 30.0 bits (66), Expect = 2.5 Identities = 26/138 (18%), Positives = 61/138 (44%), Gaps = 20/138 (14%) Frame = +3 Query: 3 KLSVSIQEEQLKSMQAEMARLS----------LEKQLAQVQEKLRLLSLEKH---GETSK 143 KL + E++ ++ E+ RL +++++ + L EK E Sbjct: 1655 KLQTHVMEQENLLLKDELERLKQLHRCPDLSDFQQKMSSILSYNEKLLKEKEVLSEELKS 1714 Query: 144 CKDVEASKLMLQKELEMIREENRKLDDQNHS-------STSVIIRLQDEIISLKNAQRKL 302 C D A +L+ + +++E ++Q+ S S + + L+D + ++ ++ Sbjct: 1715 CADKLAESSLLEHRIATMKQEQTAWEEQSESLKSQLAVSQAKVQNLEDVLQNVNLQMAEI 1774 Query: 303 EEEVSRHVEEKKALQHEL 356 E ++ +EK+AL+ E+ Sbjct: 1775 ESDLQVTRQEKEALKQEV 1792
>JIP4_MOUSE (Q58A65) C-jun-amino-terminal kinase-interacting protein 4| (JNK-interacting protein 4) (JIP-4) (JNK-associated leucine-zipper protein) (JLP) (Sperm-associated antigen 9) (Mitogen-activated protein kinase 8-interacting protein 4) (JNK/SAPK-asso Length = 1321 Score = 38.5 bits (88), Expect = 0.007 Identities = 26/130 (20%), Positives = 60/130 (46%) Frame = +3 Query: 33 LKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIREENR 212 L M E+ L LE Q+ E L++ K+ +K ++ K +LQ ELE +++ Sbjct: 403 LLGMGREVENLILEN--TQLLETKNALNVVKNDLIAKVDELTCEKDVLQGELEAVKQAKL 460 Query: 213 KLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHIXNDRGDVER 392 KL+D+N + + + E + + ++ + K+ + E++ + +R + Sbjct: 461 KLEDKNRELEEELRKARAEAEDARQKAKDDDDSDIPTAQRKRFTRVEMARVLMERNQYKE 520 Query: 393 KHFSIKEQIQ 422 + ++E ++ Sbjct: 521 RLMELQEAVR 530
>REST_CHICK (O42184) Restin (Cytoplasmic linker protein 170) (CLIP-170)| Length = 1433 Score = 38.5 bits (88), Expect = 0.007 Identities = 39/155 (25%), Positives = 74/155 (47%), Gaps = 27/155 (17%) Frame = +3 Query: 3 KLSVSIQEEQLKSMQAEMARLSLE-----------KQLAQVQEKL--RLLSLEKHGETSK 143 KL+ + + +QL ++Q E +L+ E ++L + + L +LL ++K T K Sbjct: 1153 KLAAAQKSQQLAALQEENVKLAEELGRSRDEVTSHQKLEEERSVLNNQLLEMKKRESTLK 1212 Query: 144 CKDVEASKLMLQK--------------ELEMIREENRKLDDQNHSSTSVIIRLQDEIISL 281 K+++ + LQK ELE +R E L +N S+ + LQ + +L Sbjct: 1213 -KEIDEERASLQKSISDTSALITQKDEELEKLRNEITVLRGENASAKT----LQSVVKTL 1267 Query: 282 KNAQRKLEEEVSRHVEEKKALQHELSHIXNDRGDV 386 ++ + KLEE+V ++ KA + + + GD+ Sbjct: 1268 ESDKLKLEEKVKNLEQKLKAKSEQPLTVTSPSGDI 1302 Score = 36.2 bits (82), Expect = 0.035 Identities = 26/99 (26%), Positives = 51/99 (51%), Gaps = 4/99 (4%) Frame = +3 Query: 63 LSLEKQLAQVQEKLRLLSLEKHGETSKCKD-VEASKLMLQKELEMIREENRKLDDQNHSS 239 LSL ++++ +QEK+ E E S K+ E+S+ L+KE++ + N ++ +N S Sbjct: 536 LSLLQEISSLQEKMAAAGKEHQREMSSLKEKFESSEEALRKEIKTLSASNERMGKENESL 595 Query: 240 TSVIIRLQDE---IISLKNAQRKLEEEVSRHVEEKKALQ 347 + + E +I L + KLE ++ H + + L+ Sbjct: 596 KTKLDHANKENSDVIELWKS--KLESAIASHQQAMEELK 632
>MYSP_DERFA (Q967Z0) Paramyosin (Allergen Der f 11) (Antigen Df642) (Fragment)| Length = 692 Score = 38.5 bits (88), Expect = 0.007 Identities = 33/131 (25%), Positives = 63/131 (48%), Gaps = 3/131 (2%) Frame = +3 Query: 12 VSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQK--- 182 +S EEQL+++ + + SLEKQ +++Q ++ +L ++ T + +E L+K Sbjct: 235 ISEYEEQLEALLNKCS--SLEKQKSRLQSEVEVLIMDLEKATRHAQQLEKRVAQLEKINL 292 Query: 183 ELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSH 362 +L+ EE L +Q V I E+ L++ KL ++ + E K L +L+ Sbjct: 293 DLKNKLEEVTMLMEQAQKELRVKIA---ELQKLQHEYEKLRDQRDQLARENKKLTDDLAE 349 Query: 363 IXNDRGDVERK 395 + D R+ Sbjct: 350 AKSQLNDAHRR 360 Score = 34.3 bits (77), Expect = 0.13 Identities = 31/143 (21%), Positives = 64/143 (44%), Gaps = 19/143 (13%) Frame = +3 Query: 24 EEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEK-----HGETSKCKDVEASKLMLQKEL 188 +++ + QAE+ L + + A ++ L ++EK H K +++ + + L Sbjct: 56 DKEKQKFQAEVFELLAQLETANKEKLTALKNVEKLEYTVHELNIKIEEINRTVIELTSHK 115 Query: 189 EMIREENRKL-----------DDQNHSSTSVIIRLQDEIISLKNAQRK---LEEEVSRHV 326 + + +EN +L D+ NH T + +L+D L+ +RK LE Sbjct: 116 QRLSQENTELIKEVHEVKLQLDNANHLKTQIAQQLEDTRHRLEEEERKRASLENHAHTLE 175 Query: 327 EEKKALQHELSHIXNDRGDVERK 395 E ++L+ +L R ++ER+ Sbjct: 176 VELESLKVQLDEESEARLELERQ 198
>RAD50_THEMA (Q9X1X1) Probable DNA double-strand break repair rad50 ATPase| Length = 852 Score = 38.5 bits (88), Expect = 0.007 Identities = 27/130 (20%), Positives = 62/130 (47%) Frame = +3 Query: 6 LSVSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKE 185 LS I++ +K + + S+ Q+ +++E+L L + L+++ Sbjct: 480 LSSLIEDLLMKIEEGKKNLKSIRNQIEKIEEELHRLGYSED---------------LEEK 524 Query: 186 LEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHI 365 L+ R++ RK++++ HS + I +I ++N ++++ E+ E K + E+ + Sbjct: 525 LDEKRKKLRKIEEERHSISQKITAADVQISQIENQLKEIKGEIEAKRETLKEQREEMDQL 584 Query: 366 XNDRGDVERK 395 +D D RK Sbjct: 585 KSDFFDRLRK 594
>MYH14_HUMAN (Q7Z406) Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle| myosin heavy chain IIc) (NMHC II-C) Length = 1995 Score = 38.5 bits (88), Expect = 0.007 Identities = 28/144 (19%), Positives = 66/144 (45%), Gaps = 7/144 (4%) Frame = +3 Query: 12 VSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELE 191 V EE+ + A AR LE +L +++ ++ K + + ++A L +E+E Sbjct: 1620 VERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVE 1679 Query: 192 MIREENRKLDDQNHSST-------SVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQH 350 R ++ QN S + ++RLQ+E+ + A+R+ +++ +E Sbjct: 1680 ETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNL 1739 Query: 351 ELSHIXNDRGDVERKHFSIKEQIQ 422 + I ++ +E + ++E+++ Sbjct: 1740 SKAAILEEKRQLEGRLGQLEEELE 1763 Score = 30.4 bits (67), Expect = 1.9 Identities = 25/119 (21%), Positives = 49/119 (41%), Gaps = 4/119 (3%) Frame = +3 Query: 3 KLSVSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQK 182 +L + +QE Q ++ E AR A+ EKL+ E + + E+ + L K Sbjct: 1273 RLELQLQEVQGRAGDGERAR-------AEAAEKLQRAQAELENVSGALNEAESKTIRLSK 1325 Query: 183 ELE----MIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQ 347 EL + + L ++ + ++ R++ + +LEEE + + LQ Sbjct: 1326 ELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQ 1384 Score = 29.6 bits (65), Expect = 3.3 Identities = 30/131 (22%), Positives = 61/131 (46%), Gaps = 1/131 (0%) Frame = +3 Query: 6 LSVSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKE 185 L+ +++EEQ AR LE+Q ++ +L L K ++E + + ++ Sbjct: 1505 LTRALEEEQ-------EAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQA 1557 Query: 186 LEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNA-QRKLEEEVSRHVEEKKALQHELSH 362 +R + +L+D+ ++ +RL+ + +LK +R L+ E ++ L +L Sbjct: 1558 ANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRD 1617 Query: 363 IXNDRGDVERK 395 +R D ERK Sbjct: 1618 AEVER-DEERK 1627
>FLIP1_RAT (Q8K4T4) Filamin-A-interacting protein 1 (FILIP)| Length = 1212 Score = 38.5 bits (88), Expect = 0.007 Identities = 35/145 (24%), Positives = 69/145 (47%), Gaps = 5/145 (3%) Frame = +3 Query: 3 KLSVSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQK 182 KL V + K+ + + +LA + R L L+ G + + +++E + LQK Sbjct: 297 KLEVDFEH---KASRFSQEHEEMNAKLANQESHNRQLRLKLVGLSQRIEELEETNKSLQK 353 Query: 183 ---ELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHE 353 EL+ +RE+ K + N S + + L+ ++ ++ ++ + ++ E KK LQ E Sbjct: 354 AEEELQELREKIAKGECGNSSLMAEVESLRKRVLEMEGKDEEITKTEAQCRELKKKLQEE 413 Query: 354 LSHIXNDRGDVER--KHFSIKEQIQ 422 H R +VE+ K S E+++ Sbjct: 414 EHHSKELRLEVEKLQKRMSELEKLE 438 Score = 31.2 bits (69), Expect = 1.1 Identities = 28/130 (21%), Positives = 55/130 (42%), Gaps = 7/130 (5%) Frame = +3 Query: 27 EQLKSMQAEMARLSLEKQLAQVQEKLRL---LSLEKHGETSKCKDVEASKLMLQKELE-- 191 ++L+ Q E R LE+ L + R L EKH T + +L++E E Sbjct: 151 DRLEEKQKETYRRMLEQLLLAEKCHRRTVYELENEKHKHTDYMNKSDDFTNLLEQERERL 210 Query: 192 --MIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHI 365 ++ +E + + + +L+DE++ LK+ L +E H+E+ ++ + Sbjct: 211 KKLLEQEKAYQARKEKENAKRLNKLRDELVKLKSFALMLVDERQMHIEQLGLQSQKVQDL 270 Query: 366 XNDRGDVERK 395 + E K Sbjct: 271 TQKLREEEEK 280
>MYH4_RABIT (Q28641) Myosin-4 (Myosin heavy chain, skeletal muscle, juvenile)| Length = 1938 Score = 38.5 bits (88), Expect = 0.007 Identities = 38/134 (28%), Positives = 69/134 (51%), Gaps = 13/134 (9%) Frame = +3 Query: 24 EEQLKSMQA---EMARLSLEKQLAQVQE-KLRLLSLEKHGETSKCKDVEASKLMLQ---- 179 E+ +K +Q E +L+L+ Q+Q+ + R+ LE E+ + ++VEA K + + Sbjct: 1790 EQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEAEVESEQKRNVEAVKGLRKHERR 1849 Query: 180 -KELEMIREENRK----LDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKAL 344 KEL EE+RK L D ++ +LQ ++ S K + EE+ + ++ + + L Sbjct: 1850 VKELTYQTEEDRKNVLRLQD-------LVDKLQAKVKSYKRQAEEAEEQCNINLSKFRKL 1902 Query: 345 QHELSHIXNDRGDV 386 QHEL +R D+ Sbjct: 1903 QHELEE-AEERADI 1915 Score = 35.4 bits (80), Expect = 0.061 Identities = 28/124 (22%), Positives = 52/124 (41%), Gaps = 7/124 (5%) Frame = +3 Query: 48 AEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELE----MIREENRK 215 A+ + + +E Q+ EKL+ E SK +D +A + LQK+++ I E + Sbjct: 1065 AQESTMDIENDKQQLDEKLKKKEFEMSNLQSKIEDEQALAMQLQKKIKELQARIEELEEE 1124 Query: 216 LDDQNHSSTSVIIRLQDEIISLKNAQRKLEE---EVSRHVEEKKALQHELSHIXNDRGDV 386 ++ + S + D L+ +LEE S +E K + E + D + Sbjct: 1125 IEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEA 1184 Query: 387 ERKH 398 +H Sbjct: 1185 TLQH 1188 Score = 33.1 bits (74), Expect = 0.30 Identities = 30/143 (20%), Positives = 65/143 (45%) Frame = +3 Query: 3 KLSVSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQK 182 K S++ E + K ++ +M L EK Q+Q + SL E +C + +K+ L+ Sbjct: 863 KESLAKAEAKEKELEEKMVALMQEKNDLQLQVQAEADSLADAEE--RCDQLIKTKIQLEA 920 Query: 183 ELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSH 362 +++ + E ++ N T+ +RKLE+E S ++ L+ L+ Sbjct: 921 KIKEVTERAEDEEEINAELTA--------------KKRKLEDECSELKKDIDDLELTLAK 966 Query: 363 IXNDRGDVERKHFSIKEQIQAVN 431 + ++ E K ++ E++ ++ Sbjct: 967 VEKEKHATENKVKNLTEEMAGLD 989 Score = 32.7 bits (73), Expect = 0.39 Identities = 24/120 (20%), Positives = 57/120 (47%) Frame = +3 Query: 15 SIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEM 194 S+ + + + Q ++ LE ++ +V E+ T+K + +E L+K+++ Sbjct: 900 SLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDD 959 Query: 195 IREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHIXND 374 + K++ + H++ + + L +E+ L +E +++ +EKKALQ +D Sbjct: 960 LELTLAKVEKEKHATENKVKNLTEEMAGL-------DETIAKLTKEKKALQEAHQQTLDD 1012 Score = 28.1 bits (61), Expect = 9.7 Identities = 26/112 (23%), Positives = 50/112 (44%) Frame = +3 Query: 78 QLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIREENRKLDDQNHSSTSVIIR 257 +L Q++ R LS E K K+ L +LE ++ EN+ L + T I Sbjct: 1469 ELEASQKESRSLSTE----VFKVKNAYEESL---DQLETLKRENKNLQQEISDLTEQIAE 1521 Query: 258 LQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHIXNDRGDVERKHFSIKE 413 I L+ ++++E+E S E + AL+ + + ++ G + R + + Sbjct: 1522 GGKRIHELEKVKKQVEQEKS---ELQAALEEAEASLEHEEGKILRIQLELNQ 1570
>MYH13_HUMAN (Q9UKX3) Myosin-13 (Myosin heavy chain, skeletal muscle, extraocular)| (MyHC-eo) Length = 1938 Score = 38.5 bits (88), Expect = 0.007 Identities = 26/122 (21%), Positives = 60/122 (49%), Gaps = 7/122 (5%) Frame = +3 Query: 45 QAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEA-------SKLMLQKELEMIRE 203 ++E R LE+++ + ++ L L+ ET D E SK++L+ +++ + E Sbjct: 869 RSEARRKELEEKMVSLLQEKNDLQLQVQSETENLMDAEERCEGLIKSKILLEAKVKELTE 928 Query: 204 ENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHIXNDRGD 383 + ++ N + L+D+ SLK LE +++ +EK A ++++ ++ + Sbjct: 929 RLEEEEEMNSELVAKKRNLEDKCSSLKRDIDDLELTLTKVEKEKHATENKVKNLSEEMTA 988 Query: 384 VE 389 +E Sbjct: 989 LE 990 Score = 37.0 bits (84), Expect = 0.021 Identities = 30/144 (20%), Positives = 64/144 (44%), Gaps = 2/144 (1%) Frame = +3 Query: 3 KLSVSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLS--LEKHGETSKCKDVEASKLML 176 +L I+ E + E R L ++L ++ E+L S E +K ++ E K+ Sbjct: 1121 ELEEEIEAEHTLRAKIEKQRSDLARELEEISERLEEASGATSAQIEMNKKREAEFQKMRR 1180 Query: 177 QKELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHEL 356 E ++ E + + SV L ++I +L+ ++KLE+E S E + + Sbjct: 1181 DLEEATLQHEATAATLRKKQADSVA-ELGEQIDNLQRVKQKLEKEKSELKMEIDDMASNI 1239 Query: 357 SHIXNDRGDVERKHFSIKEQIQAV 428 + + ++ER ++++Q + Sbjct: 1240 EALSKSKSNIERTCRTVEDQFSEI 1263 Score = 35.8 bits (81), Expect = 0.046 Identities = 31/156 (19%), Positives = 65/156 (41%), Gaps = 14/156 (8%) Frame = +3 Query: 3 KLSVSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQK 182 KL+ +QE + K+ A SLEK ++Q ++ L + + C ++ + K Sbjct: 1396 KLAQRLQEAEEKTETANSKCASLEKTKQRLQGEVEDLMRDLERSHTACATLDKKQRNFDK 1455 Query: 183 --------------ELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSR 320 ELE ++E+R L + + + D++ +L+ + L+EE+S Sbjct: 1456 VLAEWKQKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLETLRRENKNLQEEISD 1515 Query: 321 HVEEKKALQHELSHIXNDRGDVERKHFSIKEQIQAV 428 E+ L + VE++ ++ ++ V Sbjct: 1516 LTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEV 1551 Score = 35.8 bits (81), Expect = 0.046 Identities = 27/130 (20%), Positives = 62/130 (47%), Gaps = 7/130 (5%) Frame = +3 Query: 6 LSVSIQEEQLKSMQAE-------MARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEAS 164 L + +Q E M AE +++ LE ++ ++ E+L +K +++E Sbjct: 891 LQLQVQSETENLMDAEERCEGLIKSKILLEAKVKELTERLEEEEEMNSELVAKKRNLEDK 950 Query: 165 KLMLQKELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKAL 344 L+++++ + K++ + H++ + + L +E+ +L EE +S+ +EKK+L Sbjct: 951 CSSLKRDIDDLELTLTKVEKEKHATENKVKNLSEEMTAL-------EENISKLTKEKKSL 1003 Query: 345 QHELSHIXND 374 Q +D Sbjct: 1004 QEAHQQTLDD 1013 Score = 30.4 bits (67), Expect = 1.9 Identities = 34/134 (25%), Positives = 63/134 (47%), Gaps = 13/134 (9%) Frame = +3 Query: 24 EEQLKSMQA---EMARLSLEKQLAQVQE-KLRLLSLEKHGETSKCKDVEASKLMLQ---- 179 E+ +K +Q E +L+L+ Q+Q+ + R+ LE + + + EA K + Sbjct: 1791 EQTVKDLQHRLDEAEQLALKGGKKQIQKLENRVRELENELDVEQKRGAEALKGAHKYERK 1850 Query: 180 -KELEMIREENRK----LDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKAL 344 KE+ EE+RK L D ++ +LQ ++ S K + EE+ + + + + Sbjct: 1851 VKEMTYQAEEDRKNILRLQD-------LVDKLQAKVKSYKRQAEEAEEQANTQLSRCRRV 1903 Query: 345 QHELSHIXNDRGDV 386 QHEL +R D+ Sbjct: 1904 QHELEEAA-ERADI 1916 Score = 28.1 bits (61), Expect = 9.7 Identities = 31/137 (22%), Positives = 60/137 (43%), Gaps = 18/137 (13%) Frame = +3 Query: 66 SLEKQLAQVQEKL--RLLSLEKHGETSKCKDVEASKLM-----LQKELEMIREENRKLDD 224 + +K LA+ ++KL LE + S+ E K+ + +LE +R EN+ L + Sbjct: 1452 NFDKVLAEWKQKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLETLRRENKNLQE 1511 Query: 225 QNHSSTSVIIRLQDEIISLKNAQRKLEEEVS----RHVEEKKALQHELSHI-------XN 371 + T I + + ++ +E+E S E + +L+HE S I Sbjct: 1512 EISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEESKILRVQLELSQ 1571 Query: 372 DRGDVERKHFSIKEQIQ 422 + +++RK E+I+ Sbjct: 1572 VKSELDRKVIEKDEEIE 1588
>TUFT1_PIG (O97557) Tuftelin (Fragment)| Length = 188 Score = 38.5 bits (88), Expect = 0.007 Identities = 33/127 (25%), Positives = 62/127 (48%), Gaps = 9/127 (7%) Frame = +3 Query: 12 VSIQEEQLKSMQAEMARLSLEKQ--LAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKE 185 V +E +++ +Q + + E Q LA+V+E + L E G+ S C+ + L+KE Sbjct: 52 VEQKEAEVEELQKRLLGMETEHQALLAKVREGVTALE-ELRGKNSDCRAEQEKAANLEKE 110 Query: 186 LEMIREENRKLDD----QNHSSTSVIIRLQDE---IISLKNAQRKLEEEVSRHVEEKKAL 344 + +RE+ LDD Q +I +LQ+ I S A ++L+E+++ E + Sbjct: 111 VAGLREKIHHLDDMLKSQQRKVRQMIEQLQNSKTVIQSKDTAIQELKEKIAYLEAENLEM 170 Query: 345 QHELSHI 365 + H+ Sbjct: 171 HDRMEHL 177
>INCE_CHICK (P53352) Inner centromere protein| Length = 877 Score = 38.5 bits (88), Expect = 0.007 Identities = 30/146 (20%), Positives = 68/146 (46%), Gaps = 7/146 (4%) Frame = +3 Query: 15 SIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLM-LQKELE 191 ++Q+E+ + E+ ++K+ + QE+ R ++ ++ E + K + A + +KE E Sbjct: 618 ALQQEEEERRHKEL----MQKKKEEEQERARKIAEQRQAEQEREKQLAAEREQERKKEQE 673 Query: 192 MIREENRKLDDQNHSSTSVIIRLQDEIISLKN------AQRKLEEEVSRHVEEKKALQHE 353 +EE R ++ RLQ E+++ K +++ EE++ ++ ++ Q + Sbjct: 674 RKKEEERIQAEKQREQQEKAARLQKEVLAAKEQLQKEMEKKEKEEQLLAEMKRQEQEQKK 733 Query: 354 LSHIXNDRGDVERKHFSIKEQIQAVN 431 L + + +H KE A N Sbjct: 734 LPEEQKAKDVAQTQHLENKENSPACN 759 Score = 32.3 bits (72), Expect = 0.51 Identities = 24/101 (23%), Positives = 44/101 (43%) Frame = +3 Query: 93 QEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIREENRKLDDQNHSSTSVIIRLQDEI 272 ++KL+ L ++ E + + VE K Q+E ++ REE + ++ Sbjct: 507 RQKLQALRKKEEAEQLRKQKVEEEKKRRQEEAKLRREERLR-----------------KV 549 Query: 273 ISLKNAQRKLEEEVSRHVEEKKALQHELSHIXNDRGDVERK 395 + + +LEEE R +E+K AL E + + E K Sbjct: 550 LQARERAEQLEEERKRRIEQKLALFDEKTEKAREERLAEEK 590 Score = 28.5 bits (62), Expect = 7.4 Identities = 29/137 (21%), Positives = 59/137 (43%), Gaps = 5/137 (3%) Frame = +3 Query: 21 QEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIR 200 +E++ + +A++ R +++ Q +E+ L E + + +E + ++ E R Sbjct: 529 EEKKRRQEEAKLRREERLRKVLQARERAEQL------EEERKRRIEQKLALFDEKTEKAR 582 Query: 201 EENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSR-----HVEEKKALQHELSHI 365 EE RL +E I + A +K+EE +R ++KALQ E Sbjct: 583 EE----------------RLAEEKIKKRAAAKKMEEAEARRRQDEEARKQKALQQE---- 622 Query: 366 XNDRGDVERKHFSIKEQ 416 + ER+H + ++ Sbjct: 623 -----EEERRHKELMQK 634
>LMNA_XENLA (P11048) Lamin-A| Length = 665 Score = 38.5 bits (88), Expect = 0.007 Identities = 33/148 (22%), Positives = 68/148 (45%), Gaps = 11/148 (7%) Frame = +3 Query: 12 VSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCK-----------DVE 158 +++ ++++S++ E ARL L ++ E ++S E G S + V Sbjct: 38 LAVYIDKVRSLELENARLRL-----RITESEDVISREVTGIKSAYETELADARKTLDSVA 92 Query: 159 ASKLMLQKELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKK 338 + LQ EL IREE+++L +N S ++ Q + L+ + ++ + EK+ Sbjct: 93 KERARLQLELSKIREEHKELKARNAKKESDLLTAQARLKDLEALLNSKDAALTTALGEKR 152 Query: 339 ALQHELSHIXNDRGDVERKHFSIKEQIQ 422 L++E+ + +E K+Q+Q Sbjct: 153 NLENEIRELKAHIAKLEASLADTKKQLQ 180
>XNIF_XENLA (P35617) Low molecular weight neuronal intermediate filament (XNIF)| Length = 470 Score = 38.1 bits (87), Expect = 0.009 Identities = 31/118 (26%), Positives = 58/118 (49%), Gaps = 5/118 (4%) Frame = +3 Query: 6 LSVSIQEEQLKSMQAEMARLSLEKQ-----LAQVQEKLRLLSLEKHGETSKCKDVEASKL 170 LS Q+ + QA++A +SLE + Q +E++ + T + + ++ Sbjct: 267 LSARNQQSSEEWYQAKIANVSLEASRNNDSVRQAKEEITEYRRQLQARTLEIDALRSANE 326 Query: 171 MLQKELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKAL 344 L+++L+ E+R ++ +H LQD I L NA R +EE++RH+ E + L Sbjct: 327 SLERQLQ--EAEDRSNEEMSH--------LQDTIGQLDNALRTTKEEMARHLREYQDL 374 Score = 31.6 bits (70), Expect = 0.87 Identities = 28/120 (23%), Positives = 56/120 (46%), Gaps = 3/120 (2%) Frame = +3 Query: 69 LEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIREENRKLDDQNHSSTSV 248 LE+Q ++ ++ LL +KH E S+ + + IRE KL++Q Sbjct: 109 LEQQNKLLESEVTLLR-QKHSEPSRLSHIYEQE---------IRELRSKLEEQEQDKDQA 158 Query: 249 IIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQH---ELSHIXNDRGDVERKHFSIKEQI 419 + + L+ + KLE+E +R E + +++ +L +R +E+K S+ ++I Sbjct: 159 QLDYEHLGACLEQLKLKLEQESARREEAEDVMKNYRKDLDQATLNRLQLEKKVESLLDEI 218
>SYCP1_RAT (Q03410) Synaptonemal complex protein 1 (SCP-1)| Length = 997 Score = 38.1 bits (87), Expect = 0.009 Identities = 36/119 (30%), Positives = 60/119 (50%), Gaps = 8/119 (6%) Frame = +3 Query: 27 EQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQ--------K 182 E+L+ +QAE ARL + +L + EK++ L E E + K+ + S L++Q K Sbjct: 227 EELR-VQAENARLEMHFKLKEDHEKIQHLEEEYQKEVNN-KENQVSLLLIQSTEKENKMK 284 Query: 183 ELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELS 359 +L + EE+R +Q T +LQDE +LK K + S + K ++Q +S Sbjct: 285 DLTFLLEESRDKANQLEEKT----KLQDE--NLKELNEKKDHLTSELEDIKMSMQRSMS 337
>SMC6_YEAST (Q12749) Structural maintenance of chromosome 6 (DNA repair protein| RHC18) (Rad18 homolog) Length = 1114 Score = 38.1 bits (87), Expect = 0.009 Identities = 32/112 (28%), Positives = 58/112 (51%), Gaps = 8/112 (7%) Frame = +3 Query: 27 EQLKSMQAEMARLSLEKQLAQVQEKLRLLSLE-KHGETSKCKDVEASKLMLQKELEMIRE 203 E+ KS QAE + + Q ++K+ L+ H E K++ K +++ELE + + Sbjct: 394 EKEKSNQAEA-----QSNIDQGRKKVDALNKTIAHLEEELTKEMGGDKDQMRQELEQLEK 448 Query: 204 ENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEE-------VSRHVEEKK 338 N KL + N+S +++ LQD +KN +R ++ E +SR ++ KK Sbjct: 449 ANEKLREVNNS---LVVSLQD----VKNEERDIQHERESELRTISRSIQNKK 493
>MYH11_RAT (Q63862) Myosin-11 (Myosin heavy chain, smooth muscle isoform)| (SMMHC) (Fragments) Length = 1327 Score = 38.1 bits (87), Expect = 0.009 Identities = 28/118 (23%), Positives = 60/118 (50%), Gaps = 1/118 (0%) Frame = +3 Query: 45 QAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIREENRKLDD 224 +A A+ LE+ ++ ++ L K ++E SK L+ ++E +R + +L+D Sbjct: 849 EALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMRTQLEELED 908 Query: 225 QNHSSTSVIIRLQDEIISLKNA-QRKLEEEVSRHVEEKKALQHELSHIXNDRGDVERK 395 + ++ +RL+ + +LK +R L+ ++ E+++ LQ +L + D ERK Sbjct: 909 ELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELED-ERK 965 Score = 33.9 bits (76), Expect = 0.18 Identities = 39/152 (25%), Positives = 67/152 (44%), Gaps = 17/152 (11%) Frame = +3 Query: 27 EQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKEL---EMI 197 +QL+ +QA+M E A+ + + K E K K +EA + LQ++L E Sbjct: 1000 KQLRKLQAQMKDFQRELDDARASRD-EIFATSKENE-KKAKSLEAELMQLQEDLAAAERA 1057 Query: 198 RE----ENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQ------ 347 R+ E +L ++ SS S LQDE L+ +LEEE+ +A+ Sbjct: 1058 RKQADLEKEELAEELASSLSGRNTLQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKA 1117 Query: 348 ----HELSHIXNDRGDVERKHFSIKEQIQAVN 431 +LS+ +K+ S ++Q++ N Sbjct: 1118 TLQAEQLSNELVTERSAAQKNESARQQLERQN 1149
>LMNA_PIG (Q3ZD69) Lamin-A/C| Length = 664 Score = 38.1 bits (87), Expect = 0.009 Identities = 32/143 (22%), Positives = 66/143 (46%), Gaps = 6/143 (4%) Frame = +3 Query: 12 VSIQEEQLKSMQAEMARLSL-----EKQLAQVQEKLRLLSLEKHGETSKCKD-VEASKLM 173 +++ ++++S++ E A L L E+ +++ ++ + G+ K D V + Sbjct: 42 LAVYIDRVRSLETENAGLRLRITESEEVVSREVSGIKSAYEAELGDARKTLDSVAKERAR 101 Query: 174 LQKELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHE 353 LQ EL +REE ++L +N ++ Q + L+ E +S + EK+ L+ E Sbjct: 102 LQLELSKVREEFKELKARNTKKEGDLMAAQARLKDLEALLNSKEAALSTALSEKRTLEGE 161 Query: 354 LSHIXNDRGDVERKHFSIKEQIQ 422 L + +E K+Q+Q Sbjct: 162 LHDLRGQVAKLEAALGEAKKQLQ 184
>MFP1_LYCES (P93203) MAR binding filament-like protein 1| Length = 697 Score = 37.7 bits (86), Expect = 0.012 Identities = 38/160 (23%), Positives = 71/160 (44%), Gaps = 21/160 (13%) Frame = +3 Query: 3 KLSVSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQK 182 K V EE+LK +++++ R EK+L + E LEK T ++ + L L + Sbjct: 543 KTIVRTLEEELKFLESQITR---EKELRKSLED----ELEK--ATESLDEINRNVLALAE 593 Query: 183 ELEMIREENRKLDDQN---------------------HSSTSVIIRLQDEIISLKNAQRK 299 ELE+ N L+D+ + S++++L E SL+ +K Sbjct: 594 ELELATSRNSSLEDEREVHRQSVSEQKQISQEAQENLEDAHSLVMKLGKERESLEKRAKK 653 Query: 300 LEEEVSRHVEEKKALQHELSHIXNDRGDVERKHFSIKEQI 419 LE+E++ E L+ +++ + D E+ KE++ Sbjct: 654 LEDEMAAAKGEILRLRSQINSVKAPVEDEEKVVAGEKEKV 693
>MYH11_CHICK (P10587) Myosin-11 (Myosin heavy chain, gizzard smooth muscle)| Length = 1978 Score = 37.7 bits (86), Expect = 0.012 Identities = 31/145 (21%), Positives = 64/145 (44%), Gaps = 8/145 (5%) Frame = +3 Query: 12 VSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELE 191 +S +E L+S +A AR EKQ + E+L L E + + ++E+ Sbjct: 1125 ISDLQEDLESEKA--ARNKAEKQKRDLSEELEALKTELEDTLDTTATQQELRAKREQEVT 1182 Query: 192 MIR----EENR----KLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQ 347 +++ EE R ++ + T + L +++ K A+ L++ ++ L Sbjct: 1183 VLKRALEEETRTHEAQVQEMRQKHTQAVEELTEQLEQFKRAKANLDKTKQTLEKDNADLA 1242 Query: 348 HELSHIXNDRGDVERKHFSIKEQIQ 422 +E+ + + DVE K ++ Q+Q Sbjct: 1243 NEIRSLSQAKQDVEHKKKKLEVQLQ 1267 Score = 37.4 bits (85), Expect = 0.016 Identities = 35/142 (24%), Positives = 61/142 (42%), Gaps = 16/142 (11%) Frame = +3 Query: 12 VSIQEEQLKSMQAEMARLS-----LEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLML 176 + I E+Q + E L L LA+ +EK + L+ K+ S ++E Sbjct: 992 ILIMEDQNNKLTKERKLLEERVSDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKE 1051 Query: 177 QKELEMIREENRKLDDQNHSSTSVIIRLQDEIISLK-----------NAQRKLEEEVSRH 323 +K + + + RKL+ ++ I LQ +I LK A +LE+E S+ Sbjct: 1052 EKSRQELEKIKRKLEGESSDLHEQIAELQAQIAELKAQLAKKEEELQAALARLEDETSQK 1111 Query: 324 VEEKKALQHELSHIXNDRGDVE 389 K ++ SHI + + D+E Sbjct: 1112 NNALKKIRELESHISDLQEDLE 1133 Score = 33.1 bits (74), Expect = 0.30 Identities = 25/118 (21%), Positives = 61/118 (51%), Gaps = 1/118 (0%) Frame = +3 Query: 45 QAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIREENRKLDD 224 +A A+ LE+ ++ ++ L K ++E SK L++++E ++ + +L+D Sbjct: 1499 EALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRTLEQQVEEMKTQLEELED 1558 Query: 225 QNHSSTSVIIRLQDEIISLKNA-QRKLEEEVSRHVEEKKALQHELSHIXNDRGDVERK 395 + ++ +RL+ + ++K+ +R L+ ++ E+++ L +L + D ERK Sbjct: 1559 ELQAAEDAKLRLEVNMQAMKSQFERDLQARDEQNEEKRRQLLKQLHEHETELED-ERK 1615 Score = 32.0 bits (71), Expect = 0.67 Identities = 32/140 (22%), Positives = 62/140 (44%), Gaps = 1/140 (0%) Frame = +3 Query: 6 LSVSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLE-KHGETSKCKDVEASKLMLQK 182 L V+ QEE++++ E+ R +Q A+ + K LE KH + + K++ KL + Sbjct: 850 LQVTRQEEEMQAKDEELQRTKERQQKAEAELK----ELEQKHTQLCEEKNLLQEKLQAET 905 Query: 183 ELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSH 362 EL EE R +RL + L+ ++E + E + LQ E Sbjct: 906 ELYAEAEEMR-------------VRLAAKKQELEEILHEMEARIEEEEERSQQLQAE--- 949 Query: 363 IXNDRGDVERKHFSIKEQIQ 422 + ++++ ++EQ++ Sbjct: 950 ----KKKMQQQMLDLEEQLE 965
>MYH10_MOUSE (Q61879) Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle| myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B) Length = 1976 Score = 37.7 bits (86), Expect = 0.012 Identities = 31/137 (22%), Positives = 63/137 (45%), Gaps = 7/137 (5%) Frame = +3 Query: 6 LSVSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKE 185 L+ +Q E +AE R L + +++E L H S+ ++ E +LQ E Sbjct: 892 LAEQLQAETELFAEAEEMRARLAAKKQELEEIL-------HDLESRVEEEEERNQILQNE 944 Query: 186 LEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEV-------SRHVEEKKAL 344 + ++ + L++Q +LQ E ++ + +K+EEEV S+ ++EKK + Sbjct: 945 KKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEVLLLEDQNSKFIKEKKLM 1004 Query: 345 QHELSHIXNDRGDVERK 395 + ++ + + E K Sbjct: 1005 EDRIAECSSQLAEEEEK 1021 Score = 35.8 bits (81), Expect = 0.046 Identities = 33/155 (21%), Positives = 68/155 (43%), Gaps = 21/155 (13%) Frame = +3 Query: 27 EQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIREE 206 ++ K M+ +A S QLA+ +EK + L+ ++ + D+E +K + + + Sbjct: 999 KEKKLMEDRIAECS--SQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKA 1056 Query: 207 NRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEV--------------SRHVEEKKAL 344 RKLD + I LQ ++ LK K EEE+ + ++ + L Sbjct: 1057 KRKLDGETTDLQDQIAELQAQVDELKVQLTKKEEELQGALARGDDETLHKNNALKVAREL 1116 Query: 345 QHELSHIXND-------RGDVERKHFSIKEQIQAV 428 Q +++ + D R E++ + E+++A+ Sbjct: 1117 QAQIAELQEDFESEKASRNKAEKQKRDLSEELEAL 1151 Score = 35.4 bits (80), Expect = 0.061 Identities = 26/147 (17%), Positives = 69/147 (46%), Gaps = 7/147 (4%) Frame = +3 Query: 3 KLSVSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQK 182 +L +++E+ + A ++ +E L ++ ++ + + + + ++A Q+ Sbjct: 1600 ELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQR 1659 Query: 183 ELEMIREENRKLDDQNHSST-------SVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKA 341 ELE R ++ Q+ S + I++LQ+E+ S + A+R E+E +E Sbjct: 1660 ELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEIAN 1719 Query: 342 LQHELSHIXNDRGDVERKHFSIKEQIQ 422 S + +++ +E + ++E+++ Sbjct: 1720 SASGKSALLDEKRRLEARIAQLEEELE 1746 Score = 28.1 bits (61), Expect = 9.7 Identities = 30/139 (21%), Positives = 61/139 (43%), Gaps = 18/139 (12%) Frame = +3 Query: 24 EEQLKSMQAEMARLSLEKQLAQVQEKLRL--------LSLEKHGETSKCKDVEASKLMLQ 179 E+Q++ M+ ++ L E Q + KLRL E+ +T ++ E +L+L+ Sbjct: 1538 EQQVEEMRTQLEELEDELQATE-DAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLLK 1596 Query: 180 KELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLE------EEVSRHVE---- 329 + +RE +L+D+ + + I LK+ + ++E +EV + + Sbjct: 1597 Q----VRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQA 1652 Query: 330 EKKALQHELSHIXNDRGDV 386 + K Q EL R ++ Sbjct: 1653 QMKDYQRELEEARASRDEI 1671
>BSG2_DROME (P11929) Blastoderm-specific protein 25D| Length = 741 Score = 37.7 bits (86), Expect = 0.012 Identities = 32/146 (21%), Positives = 64/146 (43%), Gaps = 14/146 (9%) Frame = +3 Query: 21 QEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETS---------KCKDVEASKLM 173 Q+E+L S++ +A L E + A+ L S K ETS C+D +K Sbjct: 510 QDEELTSLRQRVAELEEELKAAKEGRSLTPESRSKELETSLEQMQRAYEDCEDYWQTK-- 567 Query: 174 LQKELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRH-----VEEKK 338 L +E ++ +E + +D+ H S L +++ R+ EE+ S+ ++E+ Sbjct: 568 LSEERQLFEKERQIYEDEQHESDKKFTELMEKV-------REYEEQFSKDGRLSPIDERD 620 Query: 339 ALQHELSHIXNDRGDVERKHFSIKEQ 416 L+ + S + + + + E+ Sbjct: 621 MLEQQYSELEAEAAQLRSSSIQMLEE 646
>STU2_YEAST (P46675) Suppressor of tubulin STU2| Length = 888 Score = 37.7 bits (86), Expect = 0.012 Identities = 25/89 (28%), Positives = 47/89 (52%), Gaps = 7/89 (7%) Frame = +3 Query: 78 QLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIREE----NRKLDDQN---HS 236 +L ++Q + + E+ K + E K+ + KE EM+RE+ KL+++N S Sbjct: 667 RLQKLQNDEMIWTKERQSLLEKMNNTENYKIEMIKENEMLREQLKEAQSKLNEKNIQLRS 726 Query: 237 STSVIIRLQDEIISLKNAQRKLEEEVSRH 323 + +L D ++SL+N R +E E+ R+ Sbjct: 727 KEIDVNKLSDRVLSLENELRNMEIELDRN 755
>SMC1A_MOUSE (Q9CU62) Structural maintenance of chromosome 1-like 1 protein| (SMC1alpha protein) (Chromosome segregation protein SmcB) (Sb1.8) Length = 1233 Score = 37.7 bits (86), Expect = 0.012 Identities = 34/147 (23%), Positives = 69/147 (46%), Gaps = 18/147 (12%) Frame = +3 Query: 3 KLSVSIQEEQLKSMQAEMARLS-LEKQLAQVQEKLRLLSLEKHGET----------SKCK 149 K +++ + ++ K + E R L+ ++ + Q +L+L L H E SK K Sbjct: 189 KKNIAAERKEAKQEKEEADRYQRLKDEVVRAQVQLQLFKLY-HNEVEIEKLNKELASKNK 247 Query: 150 DVEASKLMLQKELEMIREENRKLDDQNHSSTSVI--IRLQDEIISLKNAQR-KLEEEVSR 320 ++E K + K + ++E+ ++L + I+ +D ++ K Q K +E S Sbjct: 248 EIEKDKKRMDKVEDELKEKKKELGKMMREQQQIEKEIKEKDSELNQKRPQYIKAKENTSH 307 Query: 321 HVEE----KKALQHELSHIXNDRGDVE 389 +++ KK+LQH H +GD++ Sbjct: 308 KIKKLEAAKKSLQHAQKHYKKRKGDMD 334
>MYO3_CAEEL (P12844) Myosin-3 (Myosin heavy chain A) (MHC A)| Length = 1969 Score = 37.7 bits (86), Expect = 0.012 Identities = 32/145 (22%), Positives = 67/145 (46%), Gaps = 7/145 (4%) Frame = +3 Query: 3 KLSVSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHG-------ETSKCKDVEA 161 +L ++ E+ +++ +R E++L ++ E+L E+ G E +K ++ E Sbjct: 1130 ELEEELEAERNSRQKSDRSRSEAERELEELTERL-----EQQGGATAAQLEANKKREAEI 1184 Query: 162 SKLMLQKELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKA 341 +KL +KE + + E + SV L +++ +L+ + K E E S+ + + Sbjct: 1185 AKLRREKEEDSLNHETAISSLRKRHGDSVA-ELTEQLETLQKLKAKSEAEKSKLQRDLEE 1243 Query: 342 LQHELSHIXNDRGDVERKHFSIKEQ 416 QH R D+E+ +I+ Q Sbjct: 1244 SQHATDSEVRSRQDLEKALKTIEVQ 1268 Score = 37.0 bits (84), Expect = 0.021 Identities = 31/151 (20%), Positives = 67/151 (44%), Gaps = 11/151 (7%) Frame = +3 Query: 3 KLSVSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQK 182 KL+ +Q E+ K E R LE+Q+ +++E + E D+E +K ++ Sbjct: 1018 KLNEDLQSEEDKVNHLEKIRNKLEQQMDELEENI-------DREKRSRGDIEKAKRKVEG 1070 Query: 183 ELEMIREENRKLDDQNHSSTSVIIRLQDEI-----------ISLKNAQRKLEEEVSRHVE 329 +L++ +E ++ Q H + + R ++++ + QR ++E +R+ E Sbjct: 1071 DLKVAQENIDEITKQKHDVETTLKRKEEDLHHTNAKLAENNSIIAKLQRLIKELTARNAE 1130 Query: 330 EKKALQHELSHIXNDRGDVERKHFSIKEQIQ 422 L+ EL N R +R + +++ Sbjct: 1131 ----LEEELEAERNSRQKSDRSRSEAERELE 1157 Score = 33.9 bits (76), Expect = 0.18 Identities = 35/129 (27%), Positives = 56/129 (43%) Frame = +3 Query: 3 KLSVSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQK 182 +L+V IQ+ + + E+AR LE Q+A + E+ L L E + D E Sbjct: 864 ELAVKIQKLEEAVQRGEIARSQLESQVADLVEEKNALFLSLETEKANLADAE-------- 915 Query: 183 ELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSH 362 E N KL N ++ +L D L++ Q + E+++R +KK ELS Sbjct: 916 ------ERNEKL---NQLKATLESKLSDITGQLEDMQER-NEDLAR---QKKKTDQELSD 962 Query: 363 IXNDRGDVE 389 D+E Sbjct: 963 TKKHVQDLE 971 Score = 32.0 bits (71), Expect = 0.67 Identities = 26/123 (21%), Positives = 56/123 (45%) Frame = +3 Query: 24 EEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIRE 203 +++L + + L L + A+ +++ R ++ + +D +KL KE + E Sbjct: 957 DQELSDTKKHVQDLELSLRKAEQEKQSRDHNIRSLQDEMANQDEAVAKL--NKEKKHQEE 1014 Query: 204 ENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHIXNDRGD 383 NRKL++ S +D++ L+ + KLE+++ L+ + RGD Sbjct: 1015 SNRKLNEDLQSE-------EDKVNHLEKIRNKLEQQMDE-------LEENIDREKRSRGD 1060 Query: 384 VER 392 +E+ Sbjct: 1061 IEK 1063
>KINH_CAEEL (P34540) Kinesin heavy chain (Uncoordinated protein 116)| Length = 815 Score = 37.7 bits (86), Expect = 0.012 Identities = 27/93 (29%), Positives = 49/93 (52%), Gaps = 7/93 (7%) Frame = +3 Query: 12 VSIQEEQLKSMQA-------EMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKL 170 V +QEE L +M+ E R E + Q + K + +LE+ + E KL Sbjct: 463 VLLQEEALGTMRENEELIREENNRFQKEAEDKQQEGKEMMTALEEIAVNLDVRQAECEKL 522 Query: 171 MLQKELEMIREENRKLDDQNHSSTSVIIRLQDE 269 ++ELE+++E+N+ L+D+ + +TS++ DE Sbjct: 523 --KRELEVVQEDNQSLEDRMNQATSLLNAHLDE 553
>ANT1_ONCVO (P21249) Major antigen (Myosin-like antigen)| Length = 2022 Score = 37.7 bits (86), Expect = 0.012 Identities = 31/117 (26%), Positives = 55/117 (47%), Gaps = 14/117 (11%) Frame = +3 Query: 3 KLSVSIQEEQLKSMQAEMARLS-----LEKQLAQVQEKLRLLSLEKHGETSKCKDVEASK 167 K +V E++LKS++ E A + LE ++ +++E+ L+ ++ D K Sbjct: 478 KHTVKDLEDRLKSLEQEKASIDSARHHLEDEIRKMREQFNSTLLDVERRAAEDADERIRK 537 Query: 168 L---------MLQKELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEE 311 + L +EM+ EEN++L D+N + R+QD RKLEE+ Sbjct: 538 IDEETKIRISELTNRIEMLLEENKRLKDENDGMKN---RIQDIEKEYNTIIRKLEEK 591 Score = 34.7 bits (78), Expect = 0.10 Identities = 37/155 (23%), Positives = 67/155 (43%), Gaps = 18/155 (11%) Frame = +3 Query: 12 VSIQEEQLKSMQAEMARLSLEKQLAQ----VQEKLRLLSLEKH---GETSKCKDVEASKL 170 V I E K+ E R LEK++A+ + + R L KH + K +E K Sbjct: 437 VQISELTTKNDSLEEIRRRLEKRIAEANRTITHRQRELDDAKHTVKDLEDRLKSLEQEKA 496 Query: 171 MLQKELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEE-----------VS 317 + + +E RK+ +Q +S+ + R E RK++EE + Sbjct: 497 SIDSARHHLEDEIRKMREQFNSTLLDVERRAAE--DADERIRKIDEETKIRISELTNRIE 554 Query: 318 RHVEEKKALQHELSHIXNDRGDVERKHFSIKEQIQ 422 +EE K L+ E + N D+E+++ +I +++ Sbjct: 555 MLLEENKRLKDENDGMKNRIQDIEKEYNTIIRKLE 589
>MYSP_BOOMI (Q86RN8) Paramyosin| Length = 873 Score = 37.4 bits (85), Expect = 0.016 Identities = 28/126 (22%), Positives = 63/126 (50%) Frame = +3 Query: 12 VSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELE 191 +S EEQL+++ + +LEKQ +++Q ++ +L ++ T+ ++ L+K + Sbjct: 319 ISEYEEQLEALLTRCS--NLEKQKSRLQSEVEVLIMDLEKATAHAQN-------LEKRVA 369 Query: 192 MIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHIXN 371 + + N L + T ++ + Q E+ +KL+ E + E++ ALQ E + + Sbjct: 370 QLEKLNIDLKSKVEELTILLEQSQRELRQKVAEIQKLQHEYEKMREQRDALQRENKKLVD 429 Query: 372 DRGDVE 389 D + + Sbjct: 430 DLSEAK 435 Score = 28.9 bits (63), Expect = 5.7 Identities = 29/116 (25%), Positives = 55/116 (47%), Gaps = 8/116 (6%) Frame = +3 Query: 24 EEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHG-------ETSKCKDVEASKLMLQK 182 E +L ++QA+ L K+L V E+ + +E E + VE+ K L+ Sbjct: 654 ESELSALQADYDEL--HKELRVVDERCQRTIVELKSTKDILVEEQERYIKVESIKKSLEV 711 Query: 183 ELEMIREENRKLD-DQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQ 347 E+ ++ +++ + VI +L+ I ++ + +LEEE RH E +K L+ Sbjct: 712 EVRNLQVRLEEVEANALAGGKRVIAKLEARI---RDVEIELEEEKKRHAETQKILR 764
>MYH10_RAT (Q9JLT0) Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle| myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B) Length = 1976 Score = 37.4 bits (85), Expect = 0.016 Identities = 31/137 (22%), Positives = 65/137 (47%), Gaps = 7/137 (5%) Frame = +3 Query: 6 LSVSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKE 185 L+ +Q E +AE R L + +++E L L GE + + ++ K +Q Sbjct: 892 LAEQLQAETELFAEAEEMRARLAAKKQELEEILHDLESRVEGEEERNQILQNEKKKMQAH 951 Query: 186 LEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEV-------SRHVEEKKAL 344 ++ + E+ LD++ + +LQ E ++ + +K+EEEV S+ ++EKK + Sbjct: 952 IQDLEEQ---LDEEEGARQ----KLQLEKVTAEAKIKKMEEEVLLLEDQNSKFIKEKKLM 1004 Query: 345 QHELSHIXNDRGDVERK 395 + ++ + + E K Sbjct: 1005 EDRIAECSSQLAEEEEK 1021 Score = 35.8 bits (81), Expect = 0.046 Identities = 33/155 (21%), Positives = 68/155 (43%), Gaps = 21/155 (13%) Frame = +3 Query: 27 EQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIREE 206 ++ K M+ +A S QLA+ +EK + L+ ++ + D+E +K + + + Sbjct: 999 KEKKLMEDRIAECS--SQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKA 1056 Query: 207 NRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEV--------------SRHVEEKKAL 344 RKLD + I LQ ++ LK K EEE+ + ++ + L Sbjct: 1057 KRKLDGETTDLQDQIAELQAQVDELKVQLTKKEEELQGALARGDDETLHKNNALKVAREL 1116 Query: 345 QHELSHIXND-------RGDVERKHFSIKEQIQAV 428 Q +++ + D R E++ + E+++A+ Sbjct: 1117 QAQIAELQEDFESEKASRNKAEKQKRDLSEELEAL 1151 Score = 35.4 bits (80), Expect = 0.061 Identities = 26/147 (17%), Positives = 69/147 (46%), Gaps = 7/147 (4%) Frame = +3 Query: 3 KLSVSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQK 182 +L +++E+ + A ++ +E L ++ ++ + + + + ++A Q+ Sbjct: 1600 ELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQR 1659 Query: 183 ELEMIREENRKLDDQNHSST-------SVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKA 341 ELE R ++ Q+ S + I++LQ+E+ S + A+R E+E +E Sbjct: 1660 ELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEIAN 1719 Query: 342 LQHELSHIXNDRGDVERKHFSIKEQIQ 422 S + +++ +E + ++E+++ Sbjct: 1720 SASGKSALLDEKRRLEARIAQLEEELE 1746 Score = 28.1 bits (61), Expect = 9.7 Identities = 30/139 (21%), Positives = 61/139 (43%), Gaps = 18/139 (12%) Frame = +3 Query: 24 EEQLKSMQAEMARLSLEKQLAQVQEKLRL--------LSLEKHGETSKCKDVEASKLMLQ 179 E+Q++ M+ ++ L E Q + KLRL E+ +T ++ E +L+L+ Sbjct: 1538 EQQVEEMRTQLEELEDELQATE-DAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLLK 1596 Query: 180 KELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLE------EEVSRHVE---- 329 + +RE +L+D+ + + I LK+ + ++E +EV + + Sbjct: 1597 Q----VRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQA 1652 Query: 330 EKKALQHELSHIXNDRGDV 386 + K Q EL R ++ Sbjct: 1653 QMKDYQRELEEARASRDEI 1671
>MYH10_BOVIN (Q27991) Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle| myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B) Length = 1976 Score = 37.4 bits (85), Expect = 0.016 Identities = 30/137 (21%), Positives = 63/137 (45%), Gaps = 7/137 (5%) Frame = +3 Query: 6 LSVSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKE 185 L+ +Q E +AE R L + +++E L H S+ ++ E +LQ E Sbjct: 892 LAEQLQAETELFAEAEEMRARLAAKKQELEEIL-------HDLESRVEEEEERNQILQNE 944 Query: 186 LEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEV-------SRHVEEKKAL 344 + ++ + L++Q +LQ E ++ + +K+EEE+ S+ ++EKK + Sbjct: 945 KKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLM 1004 Query: 345 QHELSHIXNDRGDVERK 395 + ++ + + E K Sbjct: 1005 EDRIAECSSQLAEEEEK 1021 Score = 35.8 bits (81), Expect = 0.046 Identities = 27/96 (28%), Positives = 46/96 (47%) Frame = +3 Query: 27 EQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIREE 206 ++ K M+ +A S QLA+ +EK + L+ ++ + D+E +K + + + Sbjct: 999 KEKKLMEDRIAECS--SQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKA 1056 Query: 207 NRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEV 314 RKLD + I LQ +I LK K EEE+ Sbjct: 1057 KRKLDGETTDLQDQIAELQAQIDELKIQVAKKEEEL 1092 Score = 35.4 bits (80), Expect = 0.061 Identities = 26/147 (17%), Positives = 69/147 (46%), Gaps = 7/147 (4%) Frame = +3 Query: 3 KLSVSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQK 182 +L +++E+ + A ++ +E L ++ ++ + + + + ++A Q+ Sbjct: 1600 ELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQR 1659 Query: 183 ELEMIREENRKLDDQNHSST-------SVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKA 341 ELE R ++ Q+ S + I++LQ+E+ S + A+R E+E +E Sbjct: 1660 ELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEIAN 1719 Query: 342 LQHELSHIXNDRGDVERKHFSIKEQIQ 422 S + +++ +E + ++E+++ Sbjct: 1720 SASGKSALLDEKRRLEARIAQLEEELE 1746 Score = 35.0 bits (79), Expect = 0.079 Identities = 37/142 (26%), Positives = 67/142 (47%), Gaps = 10/142 (7%) Frame = +3 Query: 15 SIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEM 194 S+QE+Q + E AR SLEKQL +Q +L + + +++E +K L K++E+ Sbjct: 1347 SLQEQQ---EEEEEARRSLEKQLQALQAQLTDTKKKVDDDLGTIENLEEAKKKLLKDVEV 1403 Query: 195 I--REENRKL--DDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSH 362 + R E + L D + T + L D ++ L + QR++ + + ++ L E + Sbjct: 1404 LSQRLEEKALAYDKLEKTKTRLQQELDDLLVDLDH-QRQIVSNLEKKQKKFDQLLAEEKN 1462 Query: 363 IX------NDRGDVERKHFSIK 410 I DR + E + K Sbjct: 1463 ISARYAEERDRAEAEAREKETK 1484
>IF2_SALTY (Q9ZF31) Translation initiation factor IF-2| Length = 892 Score = 37.4 bits (85), Expect = 0.016 Identities = 30/115 (26%), Positives = 53/115 (46%), Gaps = 5/115 (4%) Frame = +3 Query: 24 EEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIRE 203 EEQ + E AR E+Q + ++ + E ++ EA++ ++ E + Sbjct: 106 EEQAQREAEEQARREAEEQAKREAQQ------KAEREAAEQAKREAAEKAKREAAEKDKV 159 Query: 204 ENRKLDDQNHSSTSVIIRLQDEIISLKN-----AQRKLEEEVSRHVEEKKALQHE 353 N++ DD ++ + R ++E LK A+RKLEEE R EE + + E Sbjct: 160 SNQQTDDMTKTAQAEKARRENEAAELKRKAEEEARRKLEEEARRVAEEARRMAEE 214
>IF2_SALTI (Q8Z3H7) Translation initiation factor IF-2| Length = 892 Score = 37.4 bits (85), Expect = 0.016 Identities = 30/115 (26%), Positives = 53/115 (46%), Gaps = 5/115 (4%) Frame = +3 Query: 24 EEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIRE 203 EEQ + E AR E+Q + ++ + E ++ EA++ ++ E + Sbjct: 106 EEQAQREAEEQARREAEEQAKREAQQ------KAEREAAEQAKREAAEKAKREAAEKDKV 159 Query: 204 ENRKLDDQNHSSTSVIIRLQDEIISLKN-----AQRKLEEEVSRHVEEKKALQHE 353 N++ DD ++ + R ++E LK A+RKLEEE R EE + + E Sbjct: 160 SNQQTDDMTKTAQAEKARRENEAAELKRKAEEEARRKLEEEARRVAEEARRMAEE 214
>IF2_SALPA (Q5PLB0) Translation initiation factor IF-2| Length = 892 Score = 37.4 bits (85), Expect = 0.016 Identities = 30/115 (26%), Positives = 53/115 (46%), Gaps = 5/115 (4%) Frame = +3 Query: 24 EEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIRE 203 EEQ + E AR E+Q + ++ + E ++ EA++ ++ E + Sbjct: 106 EEQAQREAEEQARREAEEQAKREAQQ------KAEREAAEQAKREAAEKAKREAAEKDKV 159 Query: 204 ENRKLDDQNHSSTSVIIRLQDEIISLKN-----AQRKLEEEVSRHVEEKKALQHE 353 N++ DD ++ + R ++E LK A+RKLEEE R EE + + E Sbjct: 160 SNQQTDDMTKTAQAEKARRENEAAELKRKAEEEARRKLEEEARRVAEEARRMAEE 214
>IF2_SALCH (Q57JH9) Translation initiation factor IF-2| Length = 892 Score = 37.4 bits (85), Expect = 0.016 Identities = 30/115 (26%), Positives = 53/115 (46%), Gaps = 5/115 (4%) Frame = +3 Query: 24 EEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIRE 203 EEQ + E AR E+Q + ++ + E ++ EA++ ++ E + Sbjct: 106 EEQAQREAEEQARREAEEQAKREAQQ------KAEREAAEQAKREAAEKAKREAAEKDKV 159 Query: 204 ENRKLDDQNHSSTSVIIRLQDEIISLKN-----AQRKLEEEVSRHVEEKKALQHE 353 N++ DD ++ + R ++E LK A+RKLEEE R EE + + E Sbjct: 160 SNQQTDDMTKTAQAEKARRENEAAELKRKAEEEARRKLEEEARRVAEEARRMAEE 214
>CLPB2_ANASP (Q8YM56) Chaperone clpB 2| Length = 872 Score = 37.4 bits (85), Expect = 0.016 Identities = 32/116 (27%), Positives = 60/116 (51%), Gaps = 5/116 (4%) Frame = +3 Query: 3 KLSVSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQK 182 K+ ++ + E+L + ++ +L +EK LSL+K + + + +E L+K Sbjct: 404 KMEITSKPEELDEIDRKILQLEMEK-----------LSLQKESDAASRERLER----LEK 448 Query: 183 ELEMIREENRKLDDQNHSSTSVIIRLQ---DEI--ISLKNAQRKLEEEVSRHVEEK 335 EL ++EE R L+ Q S VI +LQ +EI ++L+ Q + +++R E K Sbjct: 449 ELADLKEEQRTLNTQWQSEKDVINKLQSVKEEIDKVNLEIQQAERNYDLNRAAELK 504
>RAD50_PYRHO (O58687) DNA double-strand break repair rad50 ATPase| Length = 879 Score = 37.4 bits (85), Expect = 0.016 Identities = 24/98 (24%), Positives = 53/98 (54%), Gaps = 3/98 (3%) Frame = +3 Query: 138 SKCKDVEASKLMLQKELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVS 317 ++ +++ ++ L++ELE I+EE + L+ +S T + +RL + L + +LEE + Sbjct: 210 NEIRNISSNLPRLRRELEGIKEEVKTLEATFNSITELKLRLGE----LNGKKGRLEERIR 265 Query: 318 R---HVEEKKALQHELSHIXNDRGDVERKHFSIKEQIQ 422 + +EEK+ EL + + ++E+K + I+ Sbjct: 266 QLESGIEEKRKKSKELEEVVKELPELEKKETEYRRLIE 303 Score = 35.8 bits (81), Expect = 0.046 Identities = 31/126 (24%), Positives = 63/126 (50%) Frame = +3 Query: 27 EQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIREE 206 E++ S E+ R +K+ + +EK+ LS+E G +K +++E + ++ +E ++EE Sbjct: 643 EKVTSQLNELQRKFDQKKYEEKREKMMKLSMEIKGLETKLEELERRRDEIKSTIEKLKEE 702 Query: 207 NRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHIXNDRGDV 386 ++ + S + L+ I++K EE+ ++E KAL E N G++ Sbjct: 703 RKERE-------SAKMELEKLNIAIKRI-----EELRGKIKEYKALIKE--EALNKIGEI 748 Query: 387 ERKHFS 404 + FS Sbjct: 749 ASEIFS 754 Score = 32.0 bits (71), Expect = 0.67 Identities = 34/170 (20%), Positives = 74/170 (43%), Gaps = 42/170 (24%) Frame = +3 Query: 30 QLKSMQAEMARLSLEK----QLAQVQEKLRLLSLE---KHGETSKCKDVEASKLMLQKEL 188 + + ++ E++RLS K Q+ +++E+L ++LE + E + E++KL + E+ Sbjct: 484 EFRKVENELSRLSSLKTIADQIIEIRERLSKINLEDLKRDKEEYELLKSESNKL--KGEV 541 Query: 189 EMIREENRKLDDQNHSSTSVIIRLQ---------------------DEI----------- 272 E +++E +L+D + ST + I + DE+ Sbjct: 542 ESLKKEVNELNDYKNESTKLEIEIDKAKKELSEIEDRLLRLGFKTIDELSGRIRELEKFH 601 Query: 273 ---ISLKNAQRKLEEEVSRHVEEKKALQHELSHIXNDRGDVERKHFSIKE 413 I KNA+++L + + +E++ L + D+E+ + E Sbjct: 602 NKYIEAKNAEKELRDILESLKDEREELDKAFEELAKIETDIEKVTSQLNE 651
>CTRO_MOUSE (P49025) Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK)| (Rho-interacting, serine/threonine-protein kinase 21) Length = 2055 Score = 37.4 bits (85), Expect = 0.016 Identities = 38/142 (26%), Positives = 72/142 (50%), Gaps = 21/142 (14%) Frame = +3 Query: 9 SVSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKEL 188 ++S Q + + +QA+M + + +K++ +L+L +LEK E ++C ++E + + EL Sbjct: 1256 TISQQTKLIDFLQAKMDQPAKKKKVPLQYNELKL-ALEK--EKARCAELEEALQKTRIEL 1312 Query: 189 EMIREE--NRKLDDQNHSST----------SVIIRLQD------EIISLKNAQRK---LE 305 REE +RK D H ST S I+R + +++ +++RK Sbjct: 1313 RSAREEAAHRKATDHPHPSTPATARQQIAMSAIVRSPEHQPSAMSLLAPPSSRRKESSTP 1372 Query: 306 EEVSRHVEEKKALQHELSHIXN 371 EE SR ++E+ + H + H N Sbjct: 1373 EEFSRRLKER--MHHNIPHRFN 1392 Score = 35.4 bits (80), Expect = 0.061 Identities = 29/120 (24%), Positives = 59/120 (49%), Gaps = 15/120 (12%) Frame = +3 Query: 3 KLSVSIQEEQLKSMQAEMARLS---------LEKQLAQVQEKLRLLSLEKHGETSKCKDV 155 +LS+ +E QL ++QA A L LE+ A+ +E+++ L+ + K + Sbjct: 921 QLSLQERESQLTALQAARAALESQLRQAKTELEETTAEAEEEIQALTAHRDEIQRKFDAL 980 Query: 156 EASKLM---LQKELEMIREENRKLDDQNHSSTSVIIR---LQDEIISLKNAQRKLEEEVS 317 S + L+++L + E+N +L++QN + + DEI+ L++ L E++ Sbjct: 981 RNSCTVITDLEEQLNQLTEDNAELNNQNFYLSKQLDEASGANDEIVQLRSEVDHLRREIT 1040
>MYH1_HUMAN (P12882) Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1)| (Myosin heavy chain IIx/d) (MyHC-IIx/d) Length = 1939 Score = 37.4 bits (85), Expect = 0.016 Identities = 29/124 (23%), Positives = 53/124 (42%), Gaps = 7/124 (5%) Frame = +3 Query: 48 AEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELE----MIREENRK 215 A+ + + +E Q+ EKL+ E G SK +D +A + LQK+++ I E + Sbjct: 1066 AQESAMDIENDKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEE 1125 Query: 216 LDDQNHSSTSVIIRLQDEIISLKNAQRKLEE---EVSRHVEEKKALQHELSHIXNDRGDV 386 ++ + S + D L+ +LEE S +E K + E + D + Sbjct: 1126 IEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEA 1185 Query: 387 ERKH 398 +H Sbjct: 1186 TLQH 1189 Score = 37.0 bits (84), Expect = 0.021 Identities = 34/132 (25%), Positives = 67/132 (50%), Gaps = 11/132 (8%) Frame = +3 Query: 24 EEQLKSMQA---EMARLSLEKQLAQVQE-KLRLLSLEKHGETSKCKDVEASKLMLQKELE 191 E+ +K +Q E +L+L+ Q+Q+ + R+ LE E+ + ++VEA K + + E + Sbjct: 1791 EQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNVEAVKGLRKHERK 1850 Query: 192 MIREENRKLDDQNHSSTSVIIRLQD-------EIISLKNAQRKLEEEVSRHVEEKKALQH 350 + ++L Q I+RLQD ++ S K + EE+ + ++ + + +QH Sbjct: 1851 V-----KELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNVNLSKFRRIQH 1905 Query: 351 ELSHIXNDRGDV 386 EL +R D+ Sbjct: 1906 ELEE-AEERADI 1916 Score = 32.7 bits (73), Expect = 0.39 Identities = 24/120 (20%), Positives = 57/120 (47%) Frame = +3 Query: 15 SIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEM 194 S+ + + + Q ++ LE ++ +V E+ T+K + +E L+K+++ Sbjct: 901 SLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDD 960 Query: 195 IREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHIXND 374 + K++ + H++ + + L +E+ L +E +++ +EKKALQ +D Sbjct: 961 LELTLAKVEKEKHATENKVKNLTEEMAGL-------DETIAKLTKEKKALQEAHQQTLDD 1013 Score = 32.0 bits (71), Expect = 0.67 Identities = 28/136 (20%), Positives = 61/136 (44%) Frame = +3 Query: 24 EEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIRE 203 E + K ++ +M L EK Q+Q + SL E +C + +K+ L+ +++ + E Sbjct: 871 EAKRKELEEKMVTLMQEKNDLQLQVQAEADSLADAEE--RCDQLIKTKIQLEAKIKEVTE 928 Query: 204 ENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHIXNDRGD 383 ++ N T+ +RKLE+E S ++ L+ L+ + ++ Sbjct: 929 RAEDEEEINAELTA--------------KKRKLEDECSELKKDIDDLELTLAKVEKEKHA 974 Query: 384 VERKHFSIKEQIQAVN 431 E K ++ E++ ++ Sbjct: 975 TENKVKNLTEEMAGLD 990 Score = 28.5 bits (62), Expect = 7.4 Identities = 23/143 (16%), Positives = 58/143 (40%), Gaps = 7/143 (4%) Frame = +3 Query: 6 LSVSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQK- 182 L + ++ + + + +K LA+ ++K E + + + ++ Sbjct: 1432 LMIDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKESRSLSTELFKIKNA 1491 Query: 183 ------ELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKAL 344 +LE ++ EN+ L + T I I L+ ++++E+E S E + AL Sbjct: 1492 YEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKS---ELQAAL 1548 Query: 345 QHELSHIXNDRGDVERKHFSIKE 413 + + + ++ G + R + + Sbjct: 1549 EEAEASLEHEEGKILRIQLELNQ 1571
>MYH2_HUMAN (Q9UKX2) Myosin heavy chain, skeletal muscle, adult 2 (Myosin heavy| chain IIa) (MyHC-IIa) Length = 1941 Score = 37.4 bits (85), Expect = 0.016 Identities = 37/134 (27%), Positives = 71/134 (52%), Gaps = 10/134 (7%) Frame = +3 Query: 15 SIQEEQLKSMQAEMARLSLEKQLAQVQE-KLRLLSLEKHGETSKCKDVEASKLMLQ---- 179 ++++ QL+ +AE +L+L+ Q+Q+ + R+ LE E+ + ++ EA K + + Sbjct: 1795 TVKDLQLRLDEAE--QLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERR 1852 Query: 180 -KELEMIREENRK----LDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKAL 344 KEL EE+RK L D ++ +LQ ++ S K + EE+ + ++ + + L Sbjct: 1853 VKELTYQTEEDRKNILRLQD-------LVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKL 1905 Query: 345 QHELSHIXNDRGDV 386 QHEL +R D+ Sbjct: 1906 QHELEE-AEERADI 1918 Score = 35.0 bits (79), Expect = 0.079 Identities = 33/132 (25%), Positives = 55/132 (41%), Gaps = 7/132 (5%) Frame = +3 Query: 24 EEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELE---- 191 E LK Q + + EKQ Q+ EKL+ E SK +D +A + LQK+++ Sbjct: 1062 EGDLKLAQESIMDIENEKQ--QLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQA 1119 Query: 192 MIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEE---EVSRHVEEKKALQHELSH 362 I E +++ + S + D L+ +LEE S +E K + E Sbjct: 1120 RIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQK 1179 Query: 363 IXNDRGDVERKH 398 + D + +H Sbjct: 1180 MRRDLEEATLQH 1191 Score = 32.0 bits (71), Expect = 0.67 Identities = 28/130 (21%), Positives = 59/130 (45%), Gaps = 7/130 (5%) Frame = +3 Query: 6 LSVSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGE-------TSKCKDVEAS 164 L + +Q E AE L K Q++ K++ ++ E T+K + +E Sbjct: 893 LQLQVQAEAEGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDE 952 Query: 165 KLMLQKELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKAL 344 L+K+++ + K++ + H++ + + L +E+ L +E +++ +EKKAL Sbjct: 953 CSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGL-------DETIAKLTKEKKAL 1005 Query: 345 QHELSHIXND 374 Q +D Sbjct: 1006 QEAHQQTLDD 1015 Score = 30.4 bits (67), Expect = 1.9 Identities = 27/136 (19%), Positives = 60/136 (44%) Frame = +3 Query: 24 EEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIRE 203 E + K ++ +M L EK Q+Q + L E +C + +K+ L+ +++ + E Sbjct: 873 EAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEE--RCDQLIKTKIQLEAKIKEVTE 930 Query: 204 ENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHIXNDRGD 383 ++ N T+ +RKLE+E S ++ L+ L+ + ++ Sbjct: 931 RAEDEEEINAELTA--------------KKRKLEDECSELKKDIDDLELTLAKVEKEKHA 976 Query: 384 VERKHFSIKEQIQAVN 431 E K ++ E++ ++ Sbjct: 977 TENKVKNLTEEMAGLD 992 Score = 28.9 bits (63), Expect = 5.7 Identities = 33/145 (22%), Positives = 59/145 (40%), Gaps = 24/145 (16%) Frame = +3 Query: 3 KLSVSIQ--EEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGET------------- 137 KL+ +Q EE ++++ A+ A L KQ Q + + +L +E+ Sbjct: 1398 KLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDK 1457 Query: 138 ------SKCKDVEASKLMLQKELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRK 299 KC++ A ELE ++E R L + + D++ +LK + Sbjct: 1458 ILAEWKQKCEETHA-------ELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKN 1510 Query: 300 LEEEVS---RHVEEKKALQHELSHI 365 L++E+S + E HEL I Sbjct: 1511 LQQEISDLTEQIAEGGKRIHELEKI 1535 Score = 28.9 bits (63), Expect = 5.7 Identities = 33/149 (22%), Positives = 70/149 (46%), Gaps = 16/149 (10%) Frame = +3 Query: 27 EQLKSMQAEMARLSLEKQLAQV------------QEKLRLLSLEKHGETSKCKDVEASKL 170 E++ + +A+L+ EK+ Q ++K+ L+ K + D+E S L Sbjct: 986 EEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGS-L 1044 Query: 171 MLQKELEM-IREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSR---HVEEKK 338 +K+L M + RKL+ + I+ +++E L +K E E+S +E+++ Sbjct: 1045 EQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQ 1104 Query: 339 ALQHELSHIXNDRGDVERKHFSIKEQIQA 425 AL +L +++ + ++E+I+A Sbjct: 1105 ALGIQLQKKIK---ELQARIEELEEEIEA 1130
>ITSN1_XENLA (O42287) Intersectin-1| Length = 1270 Score = 37.4 bits (85), Expect = 0.016 Identities = 33/132 (25%), Positives = 61/132 (46%), Gaps = 7/132 (5%) Frame = +3 Query: 21 QEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIR 200 ++EQ + Q E A +++ Q QE+ R LEK +L Q+ELE R Sbjct: 375 RKEQERLAQLERAEQERKERERQDQERKRQQDLEK-------------QLEKQRELERQR 421 Query: 201 EENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEE-------KKALQHELS 359 EE R+ + + + + Q ++ +N +++L + +R E+ KK L+ EL Sbjct: 422 EEERRKEIERREAAKRELERQRQLEWERNRRQELLNQRNREQEDIVVLKAKKKTLEFELE 481 Query: 360 HIXNDRGDVERK 395 + + + +E K Sbjct: 482 ALNDKKHQLEGK 493
>TPM1_YEAST (P17536) Tropomyosin 1| Length = 199 Score = 37.0 bits (84), Expect = 0.021 Identities = 28/132 (21%), Positives = 65/132 (49%), Gaps = 20/132 (15%) Frame = +3 Query: 87 QVQEKLRLLSLE------KHGETS-KCKDVEASKLMLQKELEMIREENRKLDDQ------ 227 +++EKL L LE K+ E K KD+E + + +++ + +N++L+D+ Sbjct: 3 KIREKLSNLKLEAESWQEKYEELKEKNKDLEQENVEKENQIKSLTVKNQQLEDEIEKLEA 62 Query: 228 ----NHSSTSVIIRLQDEIISLKNAQRKLEEEVSR---HVEEKKALQHELSHIXNDRGDV 386 + + + +++I SL +LEEE+ + + E K L + H+ ++ + Sbjct: 63 GLSDSKQTEQDNVEKENQIKSLTVKNHQLEEEIEKLEAELAESKQLSEDSHHLQSNNDNF 122 Query: 387 ERKHFSIKEQIQ 422 +K+ ++E ++ Sbjct: 123 SKKNQQLEEDLE 134 Score = 28.9 bits (63), Expect = 5.7 Identities = 27/117 (23%), Positives = 56/117 (47%), Gaps = 1/117 (0%) Frame = +3 Query: 24 EEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCK-DVEASKLMLQKELEMIR 200 EE+++ ++AE+A KQL++ L+ + + + + D+E S L++ E +R Sbjct: 92 EEEIEKLEAELAE---SKQLSEDSHHLQSNNDNFSKKNQQLEEDLEESDTKLKETTEKLR 148 Query: 201 EENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHIXN 371 E + K D + L+++ + +RK EE ++ + KK L + + N Sbjct: 149 ESDLKADQLERR----VAALEEQ---REEWERKNEELTVKYEDAKKELDEIAASLEN 198
>GFAP_BOVIN (Q28115) Glial fibrillary acidic protein, astrocyte (GFAP)| Length = 428 Score = 37.0 bits (84), Expect = 0.021 Identities = 36/139 (25%), Positives = 67/139 (48%), Gaps = 6/139 (4%) Frame = +3 Query: 24 EEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHG---ETSKCKDVEASKLMLQKELEM 194 +E S +AEM + L + A EK+R L + E ++ + E +KL + E+ Sbjct: 59 KETRASERAEM--MELNDRFASYIEKVRFLEQQNKALAAELNQLRAKEPTKLADVYQAEL 116 Query: 195 IREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKK---ALQHELSHI 365 RE +LD +S + + + L ++KL++E ++ +E + A + E Sbjct: 117 -RELRLRLDQLTANSARLEVERDNLAQDLGTLRQKLQDETNQRLEAENNLAAYRQEADEA 175 Query: 366 XNDRGDVERKHFSIKEQIQ 422 R D+ERK S++E+I+ Sbjct: 176 TLARLDLERKIESLEEEIR 194
>RADI_MOUSE (P26043) Radixin (ESP10)| Length = 583 Score = 37.0 bits (84), Expect = 0.021 Identities = 23/135 (17%), Positives = 60/135 (44%) Frame = +3 Query: 18 IQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMI 197 ++ E+ K AE + +E++ ++ E+LR + + + ++ L L++E + Sbjct: 323 LENEKKKREIAEKEKERIEREKEELMERLRQIEEQTVKAQKELEEQTRKALELEQERQRA 382 Query: 198 REENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHIXNDR 377 +EE +LD + ++ + + Q +L EE++ + L+ + Sbjct: 383 KEEAERLDRERRAAEEAKSAIAKQAADQMKNQEQLAEELAEFTAKIALLEEAKKKKEEEA 442 Query: 378 GDVERKHFSIKEQIQ 422 + + K F+ +E ++ Sbjct: 443 TEWQHKAFAAQEDLE 457
>MYH11_HUMAN (P35749) Myosin-11 (Myosin heavy chain, smooth muscle isoform)| (SMMHC) Length = 1972 Score = 37.0 bits (84), Expect = 0.021 Identities = 27/118 (22%), Positives = 60/118 (50%), Gaps = 1/118 (0%) Frame = +3 Query: 45 QAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIREENRKLDD 224 +A A+ LE+ ++ ++ L K ++E SK L+ ++E ++ + +L+D Sbjct: 1494 EALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELED 1553 Query: 225 QNHSSTSVIIRLQDEIISLKNA-QRKLEEEVSRHVEEKKALQHELSHIXNDRGDVERK 395 + ++ +RL+ + +LK +R L+ ++ E+++ LQ +L + D ERK Sbjct: 1554 ELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELED-ERK 1610 Score = 34.7 bits (78), Expect = 0.10 Identities = 39/152 (25%), Positives = 68/152 (44%), Gaps = 17/152 (11%) Frame = +3 Query: 27 EQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKEL---EMI 197 +QL+ +QA+M E + A+ + + K E K K +EA + LQ++L E Sbjct: 1645 KQLRKLQAQMKDFQRELEDARASRD-EIFATAKENE-KKAKSLEADLMQLQEDLAAAERA 1702 Query: 198 RE----ENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQ------ 347 R+ E +L ++ SS S LQDE L+ +LEEE+ +A+ Sbjct: 1703 RKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKA 1762 Query: 348 ----HELSHIXNDRGDVERKHFSIKEQIQAVN 431 +LS+ +K+ S ++Q++ N Sbjct: 1763 TQQAEQLSNELATERSTAQKNESARQQLERQN 1794 Score = 32.3 bits (72), Expect = 0.51 Identities = 21/121 (17%), Positives = 56/121 (46%) Frame = +3 Query: 3 KLSVSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQK 182 ++ ++EE+ + Q + R + +Q+ ++E+L E + + ++ K+ + Sbjct: 926 EMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLE-------EEEAARQKLQLEKVTAEA 978 Query: 183 ELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSH 362 +++ + +E +DDQN+ + L++ I L + EE+ + K + +S Sbjct: 979 KIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISE 1038 Query: 363 I 365 + Sbjct: 1039 L 1039 Score = 31.6 bits (70), Expect = 0.87 Identities = 23/82 (28%), Positives = 37/82 (45%) Frame = +3 Query: 69 LEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIREENRKLDDQNHSSTSV 248 L LA+ +EK + L+ K+ S ++E +K + + + RKL+ Sbjct: 1011 LTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQ 1070 Query: 249 IIRLQDEIISLKNAQRKLEEEV 314 I LQ +I LK K EEE+ Sbjct: 1071 IADLQAQIAELKMQLAKKEEEL 1092 Score = 31.2 bits (69), Expect = 1.1 Identities = 28/128 (21%), Positives = 66/128 (51%), Gaps = 11/128 (8%) Frame = +3 Query: 6 LSVSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKE 185 L V+ QEE++++ + E+ + +Q A+ +L+ L +KH + ++ K++ +L + E Sbjct: 845 LQVTRQEEEMQAKEDELQKTKERQQKAE--NELKELE-QKHSQLTEEKNLLQEQLQAETE 901 Query: 186 LEMIREENR--------KLDDQNHSSTSVIIRLQDEIISLKNAQRKLEE---EVSRHVEE 332 L EE R +L++ H + + +D L+ ++K+ + ++ +EE Sbjct: 902 LYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEE 961 Query: 333 KKALQHEL 356 ++A + +L Sbjct: 962 EEAARQKL 969
>KI21A_HUMAN (Q7Z4S6) Kinesin family member 21A (Kinesin-like protein KIF2)| (NY-REN-62 antigen) Length = 1674 Score = 37.0 bits (84), Expect = 0.021 Identities = 27/109 (24%), Positives = 53/109 (48%), Gaps = 5/109 (4%) Frame = +3 Query: 24 EEQLKSMQAEM-----ARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKEL 188 E+QLK +Q ++ ++ L KQ+ + QEK RL ++ E ++ L+K+ Sbjct: 753 EKQLKKLQQDVMEMKKTKVRLMKQMKEEQEKARLTESRRNREIAQ----------LKKDQ 802 Query: 189 EMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEK 335 + R L+ Q + V+ R +E+ +L+ R + ++V+ V K Sbjct: 803 RKRDHQLRLLEAQKRNQEVVLRRKTEEVTALRRQVRPMSDKVAGKVTRK 851 Score = 28.5 bits (62), Expect = 7.4 Identities = 26/109 (23%), Positives = 49/109 (44%), Gaps = 6/109 (5%) Frame = +3 Query: 81 LAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIREENRKLDDQNHSSTSVIIRL 260 L+ +E + ++ L K + + K LQK E REE ++++ T + Sbjct: 528 LSSDKETIEIIDLAKKDLEKLKRKEKRKKKRLQKLEESNREERSVAGKEDNTDTDQEKKE 587 Query: 261 QDEIISLKNAQRKLEE--EVSRHVEEKKALQHELSHI----XNDRGDVE 389 + + +N + ++EE EVS H +E++ + E I +D D E Sbjct: 588 EKGVSERENNELEVEESQEVSDHEDEEEEEEEEEDDIDGGESSDESDSE 636
>SM1L2_HUMAN (Q8NDV3) Structural maintenance of chromosome 1-like 2 protein| (SMC1beta protein) Length = 1235 Score = 37.0 bits (84), Expect = 0.021 Identities = 28/117 (23%), Positives = 50/117 (42%) Frame = +3 Query: 3 KLSVSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQK 182 K+ I+EE+ K + + L+K++ +Q L LEKH CK + ++L Sbjct: 886 KVQTQIEEERKKFLAVDREVGKLQKEVVSIQTSLEQKRLEKHNLLLDCKVQDIEIILLSG 945 Query: 183 ELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHE 353 L+ I E + ++ +T I + + E + S E+ KALQ + Sbjct: 946 SLDDIIEVEMGTEAESTQAT----------IDIYEKEEAFEIDYSSLKEDLKALQSD 992
>KINH_LOLPE (P21613) Kinesin heavy chain| Length = 967 Score = 37.0 bits (84), Expect = 0.021 Identities = 29/109 (26%), Positives = 59/109 (54%), Gaps = 5/109 (4%) Frame = +3 Query: 24 EEQLKSMQAEMARLSLEKQLAQVQEKLRLLSL-EKHGETSKCKDVEASKLMLQKELEMIR 200 E+ + S+ E A+L + QE++ L +L E+ ETS+ + ++ +L+K++EM R Sbjct: 658 EDNVDSLNEEYAKL-------KAQEQMHLAALSEREKETSQASE---TREVLEKQMEMHR 707 Query: 201 EENRK----LDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEK 335 E+++K L D+ + + L+D+ L A KL+ + + +E+ Sbjct: 708 EQHQKQLQSLRDEISEKQATVDNLKDDNQRLSLALEKLQADYDKLKQEE 756
>KI21A_MOUSE (Q9QXL2) Kinesin family member 21A| Length = 1672 Score = 37.0 bits (84), Expect = 0.021 Identities = 27/109 (24%), Positives = 53/109 (48%), Gaps = 5/109 (4%) Frame = +3 Query: 24 EEQLKSMQAEM-----ARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKEL 188 E+QLK +Q ++ ++ L KQ+ + QEK RL ++ E ++ L+K+ Sbjct: 755 EKQLKKLQQDVMEMKKTKVRLMKQMKEEQEKARLTESRRNREIAQ----------LKKDQ 804 Query: 189 EMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEK 335 + R L+ Q + V+ R +E+ +L+ R + ++V+ V K Sbjct: 805 RKRDHQLRLLEAQKRNQEVVLRRKTEEVTALRRQVRPMSDKVAGKVTRK 853
>GOGB1_HUMAN (Q14789) Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa| Golgi complex-associated protein) (GCP372) Length = 3259 Score = 37.0 bits (84), Expect = 0.021 Identities = 41/148 (27%), Positives = 67/148 (45%), Gaps = 7/148 (4%) Frame = +3 Query: 3 KLSVSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQK 182 K + I+ + S +AE+ SL+++L Q L++ LE E D E KL+ +K Sbjct: 1348 KQGLEIESLKTVSHEAEVHAESLQQKLESSQ--LQIAGLEHLRELQPKLD-ELQKLISKK 1404 Query: 183 ELEMIREENRKLDDQNHSSTSVIIRLQDEIIS----LKNAQRKLEEEVSRHVEEKKALQH 350 E E+ L Q + + ++Q EII +K +LE + H E K LQ Sbjct: 1405 E-----EDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQV 1459 Query: 351 ELSHIX---NDRGDVERKHFSIKEQIQA 425 EL + + G+ R I+ ++QA Sbjct: 1460 ELCEMKQKPEEIGEESRAKQQIQRKLQA 1487 Score = 34.3 bits (77), Expect = 0.13 Identities = 31/133 (23%), Positives = 60/133 (45%) Frame = +3 Query: 15 SIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEM 194 S+ ++QL+ M M L + +++++ ++ + E + V + KEL Sbjct: 2234 SVLKDQLRQMSIHMEELKIN--ISRLEHDKQIWESKAQTEVQLQQKVCDTLQGENKELLS 2291 Query: 195 IREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHIXND 374 EE R L HSS + + +L+ E+ SLK+ L + + E+K L+ I Sbjct: 2292 QLEETRHL---YHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLE---GIIRQQ 2345 Query: 375 RGDVERKHFSIKE 413 D++ FS ++ Sbjct: 2346 EADIQNSKFSYEQ 2358 Score = 33.5 bits (75), Expect = 0.23 Identities = 31/123 (25%), Positives = 63/123 (51%), Gaps = 9/123 (7%) Frame = +3 Query: 24 EEQLKSMQAEMARLSLEKQL-AQVQEKLRLLS--LEKHGET--SKCKDVEASKLMLQKEL 188 E Q++ + E+ +L + + ++Q+KLR+L LE+H E+ + + V+ +LQ+EL Sbjct: 227 ETQVRLHEDELLQLVTQADVETEMQQKLRVLQRKLEEHEESLVGRAQVVD----LLQQEL 282 Query: 189 EMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKA----LQHEL 356 + N+ L Q + L++ + + + + L E++ V E+K LQ E+ Sbjct: 283 TAAEQRNQILSQQLQQMEAEHNTLRNTVETEREESKILLEKMELEVAERKLSFHNLQEEM 342 Query: 357 SHI 365 H+ Sbjct: 343 HHL 345 Score = 29.3 bits (64), Expect = 4.3 Identities = 27/119 (22%), Positives = 54/119 (45%), Gaps = 9/119 (7%) Frame = +3 Query: 24 EEQLKSMQAEMARLS-----LEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKEL 188 +E+++ +++ M L+ L+ +L Q +E L + K + + +V+ L KEL Sbjct: 2509 KEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVITIKDSQQKQLLEVQ---LQQNKEL 2565 Query: 189 E----MIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHE 353 E + E+ ++ ++ N LQ+E L L+ +S+ + ALQ E Sbjct: 2566 ENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDLSKEIESLKVSISQLTRQVTALQEE 2624
>BCN1_HUMAN (Q14457) Beclin-1 (Coiled-coil myosin-like BCL2-interacting| protein) (Protein GT197) Length = 450 Score = 37.0 bits (84), Expect = 0.021 Identities = 28/121 (23%), Positives = 57/121 (47%) Frame = +3 Query: 3 KLSVSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQK 182 +L+V+ E Q E+ E Q+Q +L+ L+LE+ + +DVE ++ ++ + Sbjct: 151 QLNVTENECQNYKRCLEILEQMNEDDSEQLQMELKELALEEERLIQELEDVEKNRKIVAE 210 Query: 183 ELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSH 362 LE ++ E +LD + + Q E K Q +L++E+ + + Q +L Sbjct: 211 NLEKVQAEAERLDQEE-------AQYQREYSEFKRQQLELDDELKSVENQMRYAQTQLDK 263 Query: 363 I 365 + Sbjct: 264 L 264 Score = 28.1 bits (61), Expect = 9.7 Identities = 17/94 (18%), Positives = 46/94 (48%), Gaps = 5/94 (5%) Frame = +3 Query: 18 IQEEQLKSMQAEMARLSLEKQ-----LAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQK 182 + E+ + +Q E+ L+LE++ L V++ ++++ ++ + ++ + Q+ Sbjct: 172 MNEDDSEQLQMELKELALEEERLIQELEDVEKNRKIVAENLEKVQAEAERLDQEEAQYQR 231 Query: 183 ELEMIREENRKLDDQNHSSTSVIIRLQDEIISLK 284 E + + +LDD+ S + + Q ++ LK Sbjct: 232 EYSEFKRQQLELDDELKSVENQMRYAQTQLDKLK 265
>Y1275_ARATH (P61430) Hypothetical protein At1g22275| Length = 856 Score = 37.0 bits (84), Expect = 0.021 Identities = 34/156 (21%), Positives = 66/156 (42%), Gaps = 14/156 (8%) Frame = +3 Query: 6 LSVSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKE 185 L + +E++ S E+ L LEKQ K E+ G S + +A L+ Sbjct: 165 LRLDAAKEEITSRDKELEELKLEKQ-----HKEMFYQTERCGTASLIEKKDAVITELETT 219 Query: 186 LEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLE--------------EEVSRH 323 + + KL+ Q + +DE+I L + Q KLE E++ R Sbjct: 220 AAERKLKIEKLNSQLEKLHLELTTKEDEVIHLVSIQEKLEKEKTNVQLSSDELFEKLVRS 279 Query: 324 VEEKKALQHELSHIXNDRGDVERKHFSIKEQIQAVN 431 +E K L + ++ + ++++K+ + KE+ ++ Sbjct: 280 EQEVKKLDELVHYLIAELTELDKKNLTFKEKFDKLS 315
>TPM1_COTJA (P58773) Tropomyosin 1 alpha chain (Alpha-tropomyosin)| Length = 284 Score = 37.0 bits (84), Expect = 0.021 Identities = 26/113 (23%), Positives = 50/113 (44%) Frame = +3 Query: 90 VQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIREENRKLDDQNHSSTSVIIRLQDE 269 +++K+++L L+K + + EA K EE K +L+DE Sbjct: 4 IKKKMQMLKLDKENALDRAEQAEADK--------KAAEERSK-------------QLEDE 42 Query: 270 IISLKNAQRKLEEEVSRHVEEKKALQHELSHIXNDRGDVERKHFSIKEQIQAV 428 +++L+ + E+E+ ++ E K Q +L D E + S+ +IQ V Sbjct: 43 LVALQKKLKGTEDELDKYSESLKDAQEKLELADKKATDAESEVASLNRRIQLV 95 Score = 33.9 bits (76), Expect = 0.18 Identities = 27/108 (25%), Positives = 51/108 (47%) Frame = +3 Query: 51 EMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIREENRKLDDQN 230 E A LS E + A+++E+L+ + T+ K +EA ++ + EE + L D+ Sbjct: 181 ERAELS-ESKCAELEEELKTV-------TNNLKSLEAQAEKYSQKEDKYEEEIKVLTDKL 232 Query: 231 HSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHIXND 374 + + + + L+ + LE+E+ + KA+ EL H ND Sbjct: 233 KEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALND 280
>TPM1_CHICK (P04268) Tropomyosin 1 alpha chain (Alpha-tropomyosin)| Length = 284 Score = 37.0 bits (84), Expect = 0.021 Identities = 26/113 (23%), Positives = 50/113 (44%) Frame = +3 Query: 90 VQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIREENRKLDDQNHSSTSVIIRLQDE 269 +++K+++L L+K + + EA K EE K +L+DE Sbjct: 4 IKKKMQMLKLDKENALDRAEQAEADK--------KAAEERSK-------------QLEDE 42 Query: 270 IISLKNAQRKLEEEVSRHVEEKKALQHELSHIXNDRGDVERKHFSIKEQIQAV 428 +++L+ + E+E+ ++ E K Q +L D E + S+ +IQ V Sbjct: 43 LVALQKKLKGTEDELDKYSESLKDAQEKLELADKKATDAESEVASLNRRIQLV 95 Score = 33.9 bits (76), Expect = 0.18 Identities = 27/108 (25%), Positives = 51/108 (47%) Frame = +3 Query: 51 EMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIREENRKLDDQN 230 E A LS E + A+++E+L+ + T+ K +EA ++ + EE + L D+ Sbjct: 181 ERAELS-ESKCAELEEELKTV-------TNNLKSLEAQAEKYSQKEDKYEEEIKVLTDKL 232 Query: 231 HSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHIXND 374 + + + + L+ + LE+E+ + KA+ EL H ND Sbjct: 233 KEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALND 280
>PCNT_HUMAN (O95613) Pericentrin (Pericentrin B) (Kendrin)| Length = 3336 Score = 37.0 bits (84), Expect = 0.021 Identities = 35/150 (23%), Positives = 69/150 (46%), Gaps = 16/150 (10%) Frame = +3 Query: 21 QEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETS-----------KCKDVEASK 167 Q + + ++ E RLSL + Q +L +L+K ET+ + +++ + Sbjct: 238 QSQAVHGLELEALRLSLSN-MHTAQLELTQANLQKEKETALTELREMLNSRRAQELALLQ 296 Query: 168 LMLQKELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQ 347 Q ELE++RE++ + ++ V++R E LK KL+ E+ ++ + K L+ Sbjct: 297 SRQQHELELLREQHAREKEE------VVLRCGQEAAELK---EKLQSEMEKNAQIVKTLK 347 Query: 348 HELSH-----IXNDRGDVERKHFSIKEQIQ 422 + + N R ++ KH S E +Q Sbjct: 348 EDWESEKDLCLENLRKELSAKHQSEMEDLQ 377 Score = 29.6 bits (65), Expect = 3.3 Identities = 34/121 (28%), Positives = 51/121 (42%), Gaps = 25/121 (20%) Frame = +3 Query: 72 EKQLAQVQEKLRLLSLEKHGETSKCKD-VEASKLMLQKELEMIREENRKLDDQNHSSTSV 248 E QL Q L L + E K+ +E K L+ + E I N KLD QN + Sbjct: 1638 EIQLEVTQRAL----LRRESEVLDLKEQLEKMKGDLESKNEEILHLNLKLDMQNSQTAVS 1693 Query: 249 IIRLQDEIISLK--------------------NAQRKLEEEVSRHVEEK----KALQHEL 356 + L++E SLK Q++L++E + +E+ + LQHEL Sbjct: 1694 LRELEEENTSLKVIYTRSSEIEELKATIENLQENQKRLQKEKAEEIEQLHEVIEKLQHEL 1753 Query: 357 S 359 S Sbjct: 1754 S 1754 Score = 28.1 bits (61), Expect = 9.7 Identities = 23/88 (26%), Positives = 40/88 (45%) Frame = +3 Query: 45 QAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIREENRKLDD 224 QAE A +LE EKLR +HG + + + + +K+LE + +D Sbjct: 400 QAERALRNLESHHQAAIEKLREDLQSEHGRCLEDLEFKFKESEKEKQLE-LENLQASYED 458 Query: 225 QNHSSTSVIIRLQDEIISLKNAQRKLEE 308 S I RL ++ S + ++++L E Sbjct: 459 LKAQSQEEIRRLWSQLDSARTSRQELSE 486
>SYCP1_MESAU (Q60563) Synaptonemal complex protein 1 (SCP-1) (Meiotic chromosome| synaptic protein) (Fragment) Length = 845 Score = 37.0 bits (84), Expect = 0.021 Identities = 35/119 (29%), Positives = 61/119 (51%), Gaps = 8/119 (6%) Frame = +3 Query: 27 EQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQ--------K 182 E+L+ +QAE ARL + +L + EK++ L E E + K+ + S L++Q K Sbjct: 79 EELR-VQAENARLDMHFKLKEDHEKIQHLQEEYKKEVND-KENQVSLLLIQRTEKENKMK 136 Query: 183 ELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELS 359 +L + EE+R +Q T +LQDE ++K +K + S + K +LQ ++ Sbjct: 137 DLTFLLEESRDKVNQLEDKT----KLQDE--NVKELNKKKDHLTSELEDTKMSLQRSMN 189 Score = 33.1 bits (74), Expect = 0.30 Identities = 36/144 (25%), Positives = 67/144 (46%), Gaps = 9/144 (6%) Frame = +3 Query: 18 IQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMI 197 ++ E+LK + AE +L EK+ +EK E + K+ E + L+ +E E+ Sbjct: 284 VKLEELKKILAEDQKLLDEKK-----------QVEKLAEELQGKEQELTLLLQTREKEVH 332 Query: 198 REENR----KLDDQNHSSTSVIIRLQDEIISLKNAQ-----RKLEEEVSRHVEEKKALQH 350 E + K+ DQN+S ++ + E LKNA+ KL E ++ +E + Sbjct: 333 DLEEQLLVTKISDQNYSKQVEELKTKLEEEKLKNAELTASCGKLSLENNKLTQETNDMAL 392 Query: 351 ELSHIXNDRGDVERKHFSIKEQIQ 422 EL D + +++ + +QI+ Sbjct: 393 ELKKYQEDITNSKKQEERMLKQIE 416
>MYH6_HUMAN (P13533) Myosin heavy chain, cardiac muscle alpha isoform| (MyHC-alpha) Length = 1939 Score = 37.0 bits (84), Expect = 0.021 Identities = 34/132 (25%), Positives = 57/132 (43%), Gaps = 7/132 (5%) Frame = +3 Query: 24 EEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELE---- 191 E LK Q + + LE Q++EKL+ + + + SK +D +A L LQK+L+ Sbjct: 1058 EGDLKLTQESI--MDLENDKLQLEEKLKKKEFDINQQNSKIEDEQALALQLQKKLKENQA 1115 Query: 192 MIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEE---EVSRHVEEKKALQHELSH 362 I E +L+ + + V D L+ +LEE S +E K + E Sbjct: 1116 RIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQK 1175 Query: 363 IXNDRGDVERKH 398 + D + +H Sbjct: 1176 MRRDLEEATLQH 1187 Score = 34.7 bits (78), Expect = 0.10 Identities = 29/143 (20%), Positives = 67/143 (46%) Frame = +3 Query: 3 KLSVSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQK 182 K ++ E + K ++ +M L EK Q+Q + +L E +C + +K+ L+ Sbjct: 862 KETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAEE--RCDQLIKNKIQLEA 919 Query: 183 ELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSH 362 + ++E N +L+D+ + + + +RKLE+E S ++ L+ L+ Sbjct: 920 K---VKEMNERLEDEEEMNAELTAK-----------KRKLEDECSELKKDIDDLELTLAK 965 Query: 363 IXNDRGDVERKHFSIKEQIQAVN 431 + ++ E K ++ E++ ++ Sbjct: 966 VEKEKHATENKVKNLTEEMAGLD 988 Score = 33.9 bits (76), Expect = 0.18 Identities = 31/130 (23%), Positives = 62/130 (47%), Gaps = 7/130 (5%) Frame = +3 Query: 6 LSVSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLS--LEKHGE-----TSKCKDVEAS 164 L + +Q EQ AE L K Q++ K++ ++ LE E T+K + +E Sbjct: 889 LQLQVQAEQDNLNDAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDE 948 Query: 165 KLMLQKELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKAL 344 L+K+++ + K++ + H++ + + L +E+ L +E +++ +EKKAL Sbjct: 949 CSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGL-------DEIIAKLTKEKKAL 1001 Query: 345 QHELSHIXND 374 Q +D Sbjct: 1002 QEAHQQALDD 1011 Score = 33.5 bits (75), Expect = 0.23 Identities = 31/149 (20%), Positives = 65/149 (43%), Gaps = 22/149 (14%) Frame = +3 Query: 6 LSVSIQEEQLKSMQAEMARLSLEKQLAQVQEKL-RLLSLEKHGETSKCKDVEASKLMLQK 182 ++ +++EQ S E + ++E+ + +Q +L + G + + +EA L+ Sbjct: 1767 MAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEG 1826 Query: 183 ELEMIREEN--------------RKLDDQNHSSTSVIIRLQDEIISL-------KNAQRK 299 ELE ++ N ++L Q ++RLQD + L K + Sbjct: 1827 ELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKKNLLRLQDLVDKLQLKVKAYKRQAEE 1886 Query: 300 LEEEVSRHVEEKKALQHELSHIXNDRGDV 386 EE+ + ++ + + +QHEL +R D+ Sbjct: 1887 AEEQANTNLSKFRKVQHELDE-AEERADI 1914 Score = 33.1 bits (74), Expect = 0.30 Identities = 31/144 (21%), Positives = 56/144 (38%), Gaps = 28/144 (19%) Frame = +3 Query: 36 KSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELE-------- 191 ++ + E A+ L ++L +E + ++ +KC +E +K LQ E+E Sbjct: 1384 RTEELEEAKKKLAQRLQDAEEAVEAVN-------AKCSSLEKTKHRLQNEIEDLMVDVER 1436 Query: 192 -----------------MIREENRKLDDQN---HSSTSVIIRLQDEIISLKNAQRKLEEE 311 ++ E +K ++ SS L E+ LKNA + E Sbjct: 1437 SNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEH 1496 Query: 312 VSRHVEEKKALQHELSHIXNDRGD 383 + E K LQ E+S + G+ Sbjct: 1497 LETFKRENKNLQEEISDLTEQLGE 1520 Score = 28.9 bits (63), Expect = 5.7 Identities = 28/126 (22%), Positives = 62/126 (49%), Gaps = 16/126 (12%) Frame = +3 Query: 27 EQLKSMQAEMARLSLEKQLAQV------------QEKLRLLSLEKHGETSKCKDVEASKL 170 E++ + +A+L+ EK+ Q ++K+ LS K + D+E S L Sbjct: 982 EEMAGLDEIIAKLTKEKKALQEAHQQALDDLQVEEDKVNSLSKSKVKLEQQVDDLEGS-L 1040 Query: 171 MLQKELEM-IREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRH---VEEKK 338 +K++ M + RKL+ + I+ L+++ + L+ +K E ++++ +E+++ Sbjct: 1041 EQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQ 1100 Query: 339 ALQHEL 356 AL +L Sbjct: 1101 ALALQL 1106
>MYH4_HUMAN (Q9Y623) Myosin-4 (Myosin heavy chain, skeletal muscle, fetal)| (Myosin heavy chain IIb) (MyHC-IIb) Length = 1939 Score = 37.0 bits (84), Expect = 0.021 Identities = 37/134 (27%), Positives = 68/134 (50%), Gaps = 13/134 (9%) Frame = +3 Query: 24 EEQLKSMQ---AEMARLSLEKQLAQVQE-KLRLLSLEKHGETSKCKDVEASKLMLQ---- 179 E+ +K +Q E +L+L+ Q+Q+ + R+ LE E+ + +VEA K + + Sbjct: 1791 EQTVKDLQLRLGEAEQLALKGGKKQIQKLEARVRELESEVESEQKHNVEAVKGLRKHERR 1850 Query: 180 -KELEMIREENRK----LDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKAL 344 KEL EE+RK L D ++ +LQ ++ + K + EE+ + ++ + + L Sbjct: 1851 VKELTYQTEEDRKNILRLQD-------LVDKLQTKVKAYKRQAEEAEEQSNVNLAKFRKL 1903 Query: 345 QHELSHIXNDRGDV 386 QHEL +R D+ Sbjct: 1904 QHELEE-AEERADI 1916 Score = 35.4 bits (80), Expect = 0.061 Identities = 34/149 (22%), Positives = 68/149 (45%), Gaps = 14/149 (9%) Frame = +3 Query: 18 IQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMI 197 +Q E+ K A+ LE+Q+ ++ SLE+ E C D+E +K L+ +L++ Sbjct: 1014 LQMEEDKVNTLTKAKTKLEQQVDDLEG-----SLEQ--EKKLCMDLERAKRKLEGDLKLA 1066 Query: 198 REE-----------NRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEE---EVSRHVEEK 335 +E N KL + +++ +++DE Q+K++E + EE Sbjct: 1067 QESTMDTENDKQQLNEKLKKKEFEMSNLQGKIEDEQALAMQLQKKIKELQARIEELEEEI 1126 Query: 336 KALQHELSHIXNDRGDVERKHFSIKEQIQ 422 +A + + R D+ R+ I E+++ Sbjct: 1127 EAERASRAKAEKQRSDLSRELEEISERLE 1155 Score = 32.7 bits (73), Expect = 0.39 Identities = 29/123 (23%), Positives = 56/123 (45%), Gaps = 14/123 (11%) Frame = +3 Query: 6 LSVSIQEEQLKSMQAEMARLSLEKQLA--------------QVQEKLRLLSLEKHGETSK 143 L S+++E+ M E A+ LE L Q+ EKL+ E K Sbjct: 1038 LEGSLEQEKKLCMDLERAKRKLEGDLKLAQESTMDTENDKQQLNEKLKKKEFEMSNLQGK 1097 Query: 144 CKDVEASKLMLQKELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRH 323 +D +A + LQK+++ ++ +L+++ + + + + + L R+L EE+S Sbjct: 1098 IEDEQALAMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDL---SREL-EEISER 1153 Query: 324 VEE 332 +EE Sbjct: 1154 LEE 1156 Score = 32.0 bits (71), Expect = 0.67 Identities = 28/130 (21%), Positives = 59/130 (45%), Gaps = 7/130 (5%) Frame = +3 Query: 6 LSVSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGE-------TSKCKDVEAS 164 L + +Q E AE L K Q++ K++ ++ E T+K + +E Sbjct: 891 LQLQVQAEADALADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDE 950 Query: 165 KLMLQKELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKAL 344 L+K+++ + K++ + H++ + + L +E+ L +E +++ +EKKAL Sbjct: 951 CSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGL-------DETIAKLTKEKKAL 1003 Query: 345 QHELSHIXND 374 Q +D Sbjct: 1004 QEAHQQTLDD 1013 Score = 30.8 bits (68), Expect = 1.5 Identities = 27/136 (19%), Positives = 61/136 (44%) Frame = +3 Query: 24 EEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIRE 203 E + K ++ +M L EK Q+Q + +L E +C + +K+ L+ +++ + E Sbjct: 871 EAKRKELEEKMVTLMQEKNDLQLQVQAEADALADAEE--RCDQLIKTKIQLEAKIKEVTE 928 Query: 204 ENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHIXNDRGD 383 ++ N T+ +RKLE+E S ++ L+ L+ + ++ Sbjct: 929 RAEDEEEINAELTA--------------KKRKLEDECSELKKDIDDLELTLAKVEKEKHA 974 Query: 384 VERKHFSIKEQIQAVN 431 E K ++ E++ ++ Sbjct: 975 TENKVKNLTEEMAGLD 990
>EEA1_HUMAN (Q15075) Early endosome antigen 1 (Endosome-associated protein| p162) (Zinc finger FYVE domain-containing protein 2) Length = 1411 Score = 37.0 bits (84), Expect = 0.021 Identities = 29/131 (22%), Positives = 58/131 (44%), Gaps = 16/131 (12%) Frame = +3 Query: 12 VSIQEEQLKSMQAEM-----ARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLML 176 +S E L + E+ A L+++L++V+ K + L E + ++ E L L Sbjct: 353 LSASETSLHRIHVELSEKGEATQKLKEELSEVETKYQHLKAEFKQLQQQREEKEQHGLQL 412 Query: 177 QKELEMIR-----------EENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRH 323 Q E+ + E + +L +Q S+ ++ + ++ L+ +LEE++ Sbjct: 413 QSEINQLHSKLLETERQLGEAHGRLKEQRQLSSEKLMDKEQQVADLQLKLSRLEEQLKEK 472 Query: 324 VEEKKALQHEL 356 V LQH+L Sbjct: 473 VTNSTELQHQL 483 Score = 28.1 bits (61), Expect = 9.7 Identities = 28/159 (17%), Positives = 66/159 (41%), Gaps = 23/159 (14%) Frame = +3 Query: 24 EEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIRE 203 E++ + ++ ++ +L + + ++ L L++ + + ++ A++L Q E+E Sbjct: 722 EQKTEELEGQIKKLEADSLEVKASKEQALQDLQQQRQLNTDLELRATELSKQLEMEKEIV 781 Query: 204 ENRKLDDQNHSSTSVIIR------------LQDEIISLKNAQRKLEEEVSRHVE------ 329 + +LD Q S I+ L+ + +L + EE++ ++ Sbjct: 782 SSTRLDLQKKSEALESIKQKLTKQEEEKQILKQDFETLSQETKIQHEELNNRIQTTVTEL 841 Query: 330 -----EKKALQHELSHIXNDRGDVERKHFSIKEQIQAVN 431 EK+AL ELS + + V + K + + N Sbjct: 842 QKVKMEKEALMTELSTVKDKLSKVSDSLKNSKSEFEKEN 880
>CLPB_LACLA (Q9CFF3) Chaperone clpB| Length = 867 Score = 37.0 bits (84), Expect = 0.021 Identities = 30/132 (22%), Positives = 68/132 (51%), Gaps = 3/132 (2%) Frame = +3 Query: 9 SVSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKL-MLQKE 185 ++ + +E +++ EM SL +L Q +L L +E+ + D +L +++ E Sbjct: 392 AIDLVDEASATIRVEMN--SLPTELDQANRRLMQLEIEEAALKKERDDASKKRLEIIRGE 449 Query: 186 LEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSR-HVEEKKALQH-ELS 359 + +REEN +L Q + + + ++ L++A+ +LEE + ++E+ AL++ ++ Sbjct: 450 IAELREENNQLKAQWEAEKKEVGNISEKRNELEHARHELEEAQNEGNLEKAAALRYGKIP 509 Query: 360 HIXNDRGDVERK 395 I + +E K Sbjct: 510 EIEKELKAIEEK 521
>MAD1_KLULA (Q6CMM2) Spindle assembly checkpoint component MAD1 (Mitotic arrest| deficient protein 1) Length = 648 Score = 37.0 bits (84), Expect = 0.021 Identities = 31/134 (23%), Positives = 67/134 (50%), Gaps = 15/134 (11%) Frame = +3 Query: 6 LSVSIQEEQLKSMQAEMAR---LSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLML 176 L+ I+E+ L+S+ A+ R L+L+ + +Q + + L ET ++ + K M Sbjct: 3 LTPQIKEKPLESLDADQLRRRVLTLQYKYTTLQNEYEISKLSSERETYSLQN-KYDKSMN 61 Query: 177 Q-----KELEMIREENRKLDDQNHSSTS-------VIIRLQDEIISLKNAQRKLEEEVSR 320 + K+ +++ EEN KL ++ S + +I L+ +++SLKN E+ + Sbjct: 62 ELENALKDTKILYEENIKLKEELKSKDALPKEDEKIITTLRTQVVSLKNEVNLKEQRIVE 121 Query: 321 HVEEKKALQHELSH 362 + + Q+E+++ Sbjct: 122 LAHKLSSKQNEVTN 135
>HMMR_MOUSE (Q00547) Hyaluronan mediated motility receptor (Intracellular| hyaluronic acid-binding protein) (Receptor for hyaluronan-mediated motility) Length = 794 Score = 37.0 bits (84), Expect = 0.021 Identities = 41/157 (26%), Positives = 68/157 (43%), Gaps = 19/157 (12%) Frame = +3 Query: 3 KLSVSIQEEQLKSMQAEMARL--SLE------KQLAQVQEKLRLLSLEKHGETSKCKD-- 152 K+ ++ EE LK E+ L SLE KQ+ + K +LL E+ SK ++ Sbjct: 252 KVDIAQLEEDLKEKDREILSLKQSLEENITFSKQIEDLTVKCQLLETERDNLVSKDRERA 311 Query: 153 --VEASKLMLQKELEMIREENRKLDDQNHSSTSVI-------IRLQDEIISLKNAQRKLE 305 + A +L + L + R+E KL + S S++ RLQ ++ S Q ++ Sbjct: 312 ETLSAEMQILTERLALERQEYEKLQQKELQSQSLLQQEKELSARLQQQLCSF---QEEMT 368 Query: 306 EEVSRHVEEKKALQHELSHIXNDRGDVERKHFSIKEQ 416 E + EE K EL + ER ++E+ Sbjct: 369 SEKNVFKEELKLALAELDAVQQKEEQSERLVKQLEEE 405 Score = 28.9 bits (63), Expect = 5.7 Identities = 32/146 (21%), Positives = 60/146 (41%), Gaps = 36/146 (24%) Frame = +3 Query: 6 LSVSIQEEQLKSMQAEMARLSLEKQLAQVQEK-------LRLLSLEKHG-ETSKCKDVEA 161 ++ ++ EQ K + + QL VQEK LR +S + ++S K++E Sbjct: 497 VTAQLESEQEKYNDTAQSLRDVTAQLESVQEKYNDTAQSLRDVSAQLESYKSSTLKEIED 556 Query: 162 SKL----------MLQKELEMIREENRKLDDQNHSSTSVIIRLQ---------------- 263 KL M +K +E ++++ + N ++ LQ Sbjct: 557 LKLENLTLQEKVAMAEKSVEDVQQQILTAESTNQEYARMVQDLQNRSTLKEEEIKEITSS 616 Query: 264 --DEIISLKNAQRKLEEEVSRHVEEK 335 ++I LKN R+ +E+ + +EEK Sbjct: 617 FLEKITDLKNQLRQQDEDFRKQLEEK 642
>SMC2_MOUSE (Q8CG48) Structural maintenance of chromosome 2-like 1 protein| (Chromosome-associated protein E) (XCAP-E homolog) (FGF-inducible protein 16) Length = 1191 Score = 37.0 bits (84), Expect = 0.021 Identities = 32/160 (20%), Positives = 75/160 (46%), Gaps = 23/160 (14%) Frame = +3 Query: 21 QEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLE-----KHGETSKCKDVEASKLMLQKE 185 +E +L++++ E+A L V EK R L + + G+ + K ++S Q+E Sbjct: 691 KENELRALEEELAGLK------NVAEKYRQLKQQWEMKTEEGDLLQTKLQQSSYHKQQEE 744 Query: 186 LEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEK---------- 335 L+ +++ + ++ S+ + + +++ +L+N + E E + +++ Sbjct: 745 LDALKKTIEESEETLKSTKEIQKKAEEKYEALENKMKNAEAEREKELKDAQKKLDCAKTK 804 Query: 336 --------KALQHELSHIXNDRGDVERKHFSIKEQIQAVN 431 K Q E+ I + +++R+H S ++Q+ AVN Sbjct: 805 ADASSKKMKEKQQEVEAITLELEELKREHASNEQQLDAVN 844 Score = 33.5 bits (75), Expect = 0.23 Identities = 27/113 (23%), Positives = 53/113 (46%), Gaps = 2/113 (1%) Frame = +3 Query: 24 EEQLKSMQAEM--ARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMI 197 EE+ ++++ +M A EK+L Q+KL + + K K+ Q+E+E I Sbjct: 770 EEKYEALENKMKNAEAEREKELKDAQKKLDCAKTKADASSKKMKE-------KQQEVEAI 822 Query: 198 REENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHEL 356 E +L ++ S+ + + + I + + K+ EV+++ E Q EL Sbjct: 823 TLELEELKREHASNEQQLDAVNEAIKAYEGQIEKMAAEVAKNKESVNKAQDEL 875 Score = 28.1 bits (61), Expect = 9.7 Identities = 30/149 (20%), Positives = 66/149 (44%), Gaps = 7/149 (4%) Frame = +3 Query: 6 LSVSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLS-LEKHGET------SKCKDVEAS 164 L +Q+ Q E+ +L+K + + +E L+ ++K E +K K+ EA Sbjct: 729 LQTKLQQSSYHKQQEELD--ALKKTIEESEETLKSTKEIQKKAEEKYEALENKMKNAEAE 786 Query: 165 KLMLQKELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKAL 344 + +KEL ++ +KLD + + +++++ ++ +LEE H ++ L Sbjct: 787 R---EKEL---KDAQKKLDCAKTKADASSKKMKEKQQEVEAITLELEELKREHASNEQQL 840 Query: 345 QHELSHIXNDRGDVERKHFSIKEQIQAVN 431 I G +E+ + + ++VN Sbjct: 841 DAVNEAIKAYEGQIEKMAAEVAKNKESVN 869
>RAD50_PYRKO (Q5JHN1) DNA double-strand break repair rad50 ATPase| Length = 883 Score = 37.0 bits (84), Expect = 0.021 Identities = 32/110 (29%), Positives = 54/110 (49%), Gaps = 3/110 (2%) Frame = +3 Query: 69 LEKQLA---QVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIREENRKLDDQNHSS 239 +EK LA Q E LR E + ++ K++ K LQKEL + EE+ K + Sbjct: 312 IEKLLATYSQQAENLRERIDELSKKEARVKELLKEKEGLQKELGAL-EEDLKAYQRAKEL 370 Query: 240 TSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHIXNDRGDVE 389 + + RL+ + + KLE E+ + E K+ + EL I + RG+++ Sbjct: 371 MANLERLKKRLTLSEEEIEKLEAEIQKARERKEEIMKELEEIGSRRGELK 420 Score = 32.7 bits (73), Expect = 0.39 Identities = 27/125 (21%), Positives = 57/125 (45%), Gaps = 19/125 (15%) Frame = +3 Query: 24 EEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEK------------------HGETSKCK 149 E+ LK + A + +Q+ + +EKL+ LEK GE + Sbjct: 488 EKTLKKERELFALKEVLEQIRETEEKLKEYDLEKLEEANEKAEELKKKLAGLEGEIKSLE 547 Query: 150 DVEASKLMLQKELEMIREENRKLDDQNHSSTSVIIRLQ-DEIISLKNAQRKLEEEVSRHV 326 D +L+K+L ++ ++ R+L+++ S + +L ++ L+ ++LE R++ Sbjct: 548 DEIKKGELLKKKLALVEKKLRELEEERASLLGELKKLGFGDVKELEERLKELEPAYKRYI 607 Query: 327 EEKKA 341 E + A Sbjct: 608 ELRPA 612
>NIN_HUMAN (Q8N4C6) Ninein (hNinein)| Length = 2090 Score = 37.0 bits (84), Expect = 0.021 Identities = 24/133 (18%), Positives = 63/133 (47%) Frame = +3 Query: 33 LKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIREENR 212 + S++AE++ + ++ + Q + L LEK + +C D+ Q+++ + N Sbjct: 1655 VSSLEAELSEVKIQTHIVQQENHLLKDELEKMKQLHRCPDLSD----FQQKISSVLSYNE 1710 Query: 213 KLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHIXNDRGDVER 392 KL + + + + D++ LE ++ +E+K+ +H+ + + + + Sbjct: 1711 KLLKEKEALSEELNSCVDKLAK----SSLLEHRIATMKQEQKSWEHQSASLKSQLVASQE 1766 Query: 393 KHFSIKEQIQAVN 431 K ++++ +Q VN Sbjct: 1767 KVQNLEDTVQNVN 1779 Score = 36.2 bits (82), Expect = 0.035 Identities = 40/155 (25%), Positives = 74/155 (47%), Gaps = 17/155 (10%) Frame = +3 Query: 3 KLSVSIQEEQLKSMQAEMARLSLEKQ-----LAQVQEKLRLLSLEKHGETSK-----CKD 152 K +S +EQL + A+ R S +KQ ++ +++KL++L E+ E S +D Sbjct: 1197 KNQISQLQEQLMMLCADCDRASEKKQDLLFDVSVLKKKLKML--ERIPEASPKYKLLYED 1254 Query: 153 VEASKLMLQKELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEE------EV 314 V LQ+EL M+ + + N T+ + RLQDE+ +K+EE + Sbjct: 1255 VSRENDCLQEELRMMETRYDEALENNKELTAEVFRLQDEL-------KKMEEVTETFLSL 1307 Query: 315 SRHVEEKKALQHELS-HIXNDRGDVERKHFSIKEQ 416 + +E K EL+ + +G +E+ S+ ++ Sbjct: 1308 EKSYDEVKIENEELNVLVLRLQGKIEKLQESVVQR 1342 Score = 33.1 bits (74), Expect = 0.30 Identities = 30/132 (22%), Positives = 63/132 (47%), Gaps = 19/132 (14%) Frame = +3 Query: 18 IQEEQ--LKSMQAEMARLSLEKQLAQVQEKL-------RLLSLEKHG---ETSKCKDVEA 161 +Q+E LK +M +L L+ Q+K+ L EK E + C D A Sbjct: 1672 VQQENHLLKDELEKMKQLHRCPDLSDFQQKISSVLSYNEKLLKEKEALSEELNSCVDKLA 1731 Query: 162 SKLMLQKELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHV----- 326 +L+ + +++E + + Q+ S S ++ Q+++ +L++ + + ++SR Sbjct: 1732 KSSLLEHRIATMKQEQKSWEHQSASLKSQLVASQEKVQNLEDTVQNVNLQMSRMKSDLRV 1791 Query: 327 --EEKKALQHEL 356 +EK+AL+ E+ Sbjct: 1792 TQQEKEALKQEV 1803 Score = 33.1 bits (74), Expect = 0.30 Identities = 38/133 (28%), Positives = 65/133 (48%), Gaps = 16/133 (12%) Frame = +3 Query: 6 LSVSIQEEQLKSMQAEM-------ARLSLEKQLAQVQEKL--RLLSLEKHGETSKCKDVE 158 L++SI+ E + E RL LE ++ +++L ++S +K E K + E Sbjct: 601 LNMSIEAELVIEQMKEQHHRDICCLRLELEDKVRHYEKQLDETVVSCKKAQENMKQRH-E 659 Query: 159 ASKLMLQKELEMIREENRKLDDQ-------NHSSTSVIIRLQDEIISLKNAQRKLEEEVS 317 L+K++ ++ E +L Q +H +T R ++E K Q KLEEE + Sbjct: 660 NETHTLEKQISDLKNEIAELQGQAAVLKEAHHEATC---RHEEE---KKQLQVKLEEEKT 713 Query: 318 RHVEEKKALQHEL 356 H++EK LQHE+ Sbjct: 714 -HLQEKLRLQHEM 725 Score = 31.2 bits (69), Expect = 1.1 Identities = 38/166 (22%), Positives = 76/166 (45%), Gaps = 34/166 (20%) Frame = +3 Query: 18 IQEEQLKSMQAEMARLS--LEKQLAQVQEKL-------RLLSLEKHGETSKCKDVEASKL 170 +QEE+L M+ E R L+ Q+ ++Q +L R+L L + S ++VEA+ Sbjct: 528 LQEERLTQMRNEYERQCRVLQDQVDELQSELEEYRAQGRVLRLPL--KNSPSEEVEANSG 585 Query: 171 MLQKELEMIREENRKLD-------------DQNHSSTSVI-IRLQDEI-----------I 275 ++ E + EE L+ +Q+H + + L+D++ + Sbjct: 586 GIEPEHGLGSEECNPLNMSIEAELVIEQMKEQHHRDICCLRLELEDKVRHYEKQLDETVV 645 Query: 276 SLKNAQRKLEEEVSRHVEEKKALQHELSHIXNDRGDVERKHFSIKE 413 S K AQ +++ RH E L+ ++S + N+ +++ + +KE Sbjct: 646 SCKKAQENMKQ---RHENETHTLEKQISDLKNEIAELQGQAAVLKE 688 Score = 30.0 bits (66), Expect = 2.5 Identities = 19/57 (33%), Positives = 30/57 (52%), Gaps = 3/57 (5%) Frame = +3 Query: 189 EMIREENRKL---DDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQH 350 ++I EEN L D++ + I L+ E L+ RKL+E V+ V++K L H Sbjct: 1428 QVILEENTTLLGFQDKHFQHQATIAELELEKTKLQELTRKLKERVTILVKQKDVLSH 1484
>BCN1_MOUSE (O88597) Beclin-1 (Coiled-coil myosin-like BCL2-interacting| protein) Length = 448 Score = 37.0 bits (84), Expect = 0.021 Identities = 29/113 (25%), Positives = 56/113 (49%), Gaps = 7/113 (6%) Frame = +3 Query: 3 KLSVSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQK 182 +L+V+ E Q E+ E Q+Q +L+ L+LE+ + +DVE ++ ++ + Sbjct: 149 QLNVTENECQNYKRCLEILEQMNEDDSEQLQRELKELALEEERLIQELEDVEKNRKVVAE 208 Query: 183 ELEMIREENRKLDD---QNHSSTSVI----IRLQDEIISLKNAQRKLEEEVSR 320 LE ++ E +LD Q H S + L DE+ S++N R + ++ + Sbjct: 209 NLEKVQAEAERLDQEEAQYHREYSEFKRQQLELDDELKSVENQVRYAQIQLDK 261
>TPR_HUMAN (P12270) Nucleoprotein TPR| Length = 2349 Score = 36.6 bits (83), Expect = 0.027 Identities = 32/127 (25%), Positives = 59/127 (46%), Gaps = 11/127 (8%) Frame = +3 Query: 69 LEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLM-------LQKELEMIREENRKLDDQ 227 L + + ++ EKL+ + K K +++AS + L++E E++ +N L+ + Sbjct: 141 LTEDVKRLNEKLKESNTTKGELQLKLDELQASDVSVKYREKRLEQEKELLHSQNTWLNTE 200 Query: 228 NHSSTSVIIRLQ----DEIISLKNAQRKLEEEVSRHVEEKKALQHELSHIXNDRGDVERK 395 + T ++ L +EI+ LK +EEVSR E+ L+ H+ D+ K Sbjct: 201 LKTKTDELLALGREKGNEILELKCNLENKKEEVSRLEEQMNGLKTSNEHLQKHVEDLLTK 260 Query: 396 HFSIKEQ 416 KEQ Sbjct: 261 LKEAKEQ 267 Score = 31.6 bits (70), Expect = 0.87 Identities = 31/143 (21%), Positives = 68/143 (47%), Gaps = 3/143 (2%) Frame = +3 Query: 12 VSIQE-EQLKSM--QAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQK 182 VS+QE ++LK QAE SLE Q+ +Q+ L EK E ++++ + LQ Sbjct: 1471 VSVQEMQELKETLNQAETKSKSLESQVENLQKTLS----EKETE---ARNLQEQTVQLQS 1523 Query: 183 ELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSH 362 EL +R++ LQD + ++++ E+ + + A + +++H Sbjct: 1524 ELSRLRQD-----------------LQDRTTQEEQLRQQITEKEEKTRKAIVAAKSKIAH 1566 Query: 363 IXNDRGDVERKHFSIKEQIQAVN 431 + + + +++ +K++ A++ Sbjct: 1567 LAGVKDQLTKENEELKQRNGALD 1589
>MYT1_HUMAN (Q01538) Myelin transcription factor 1 (MyT1) (MyTI) (Proteolipid| protein-binding protein) (PLPB1) Length = 1121 Score = 36.6 bits (83), Expect = 0.027 Identities = 18/60 (30%), Positives = 36/60 (60%) Frame = +3 Query: 180 KELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELS 359 +E++ + +E R L++ N + +++LQ +I S++ + +EEE E+ +AL ELS Sbjct: 1002 EEIKQLNQEIRDLNESNSEMEAAMVQLQSQISSMEKNLKNIEEENKLIEEQNEALFLELS 1061
>MY18A_MOUSE (Q9JMH9) Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain)| (Molecule associated with JAK3 N-terminus) (MAJN) Length = 2035 Score = 36.6 bits (83), Expect = 0.027 Identities = 31/142 (21%), Positives = 68/142 (47%), Gaps = 3/142 (2%) Frame = +3 Query: 6 LSVSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKE 185 L +Q+ + + E + ++KQL ++ K++ E + + +E +KL L+ E Sbjct: 1515 LEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGSIQMLEQAKLRLEME 1574 Query: 186 LEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEV---SRHVEEKKALQHEL 356 +E +R+ + K + V Q LK + +LEEE + + EK+ L+ +L Sbjct: 1575 MERMRQTHSK--EMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKALREKRELESKL 1632 Query: 357 SHIXNDRGDVERKHFSIKEQIQ 422 S + + V ++ F +++++ Sbjct: 1633 STLSD---QVNQRDFESEKRLR 1651 Score = 34.7 bits (78), Expect = 0.10 Identities = 33/155 (21%), Positives = 68/155 (43%), Gaps = 23/155 (14%) Frame = +3 Query: 3 KLSVSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQK 182 ++ V ++EE +A + LE +L+ + +++ E E KD++ +K +L Sbjct: 1606 QMEVQLEEEYEDKQKALREKRELESKLSTLSDQVNQRDFES--EKRLRKDLKRTKALLAD 1663 Query: 183 ELEMI---------REENRKLDDQNHSST-----------SVIIRLQD---EIISLKNAQ 293 M+ + E +L +Q S ++ + ++D +I + A+ Sbjct: 1664 AQIMLDHLKNNAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEMEDLHLQIDDIAKAK 1723 Query: 294 RKLEEEVSRHVEEKKALQHELSHIXNDRGDVERKH 398 LEE++SR EK +Q+ L D ++ +KH Sbjct: 1724 TALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKH 1758 Score = 29.6 bits (65), Expect = 3.3 Identities = 21/118 (17%), Positives = 60/118 (50%), Gaps = 1/118 (0%) Frame = +3 Query: 72 EKQLAQ-VQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIREENRKLDDQNHSSTSV 248 +K+L Q +++K+ + + + D++A Q+ L+ ++++ ++L + + Sbjct: 1382 KKRLQQELEDKMEVEQQSRRQLERRLGDLQADSDESQRALQQLKKKCQRLTAELQDTKLH 1441 Query: 249 IIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHIXNDRGDVERKHFSIKEQIQ 422 + Q L+ QR+ + E+S+ EE + + + + ++ + + FS+K+Q++ Sbjct: 1442 LEGQQVRNHELEKKQRRFDSELSQAHEETQREKLQREKLQREKDMLLAEAFSLKQQME 1499
>OPTN_BRARE (Q5RI56) Optineurin| Length = 517 Score = 36.6 bits (83), Expect = 0.027 Identities = 41/142 (28%), Positives = 66/142 (46%), Gaps = 10/142 (7%) Frame = +3 Query: 30 QLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKEL---EMIR 200 ++K+++ ++ +L E L Q Q KL K +CKD+E L+ +L + ++ Sbjct: 239 EVKNLEDQLLKLCNE--LKQAQIKLDEAESMKRNLQDRCKDLEQDLGTLKTQLGDKQKVQ 296 Query: 201 EENRKLDDQNHSSTSVI----IRLQDE---IISLKNAQRKLEEEVSRHVEEKKALQHELS 359 EN L Q S + I + QDE + LK+A KL E+ S EEKK + S Sbjct: 297 AENDCLKVQMESLQAAIKLEQKKTQDEKNNLNQLKDAYTKLFEDYSELQEEKKKRE---S 353 Query: 360 HIXNDRGDVERKHFSIKEQIQA 425 + D D + F+ E+ A Sbjct: 354 CVSKDDYDELQTRFATAEKALA 375
>MYT1_MOUSE (Q8CFC2) Myelin transcription factor 1 (MyT1) (Neural zinc finger| factor 2) (NZF-2) Length = 1127 Score = 36.6 bits (83), Expect = 0.027 Identities = 18/60 (30%), Positives = 36/60 (60%) Frame = +3 Query: 180 KELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELS 359 +E++ + +E R L++ N + +++LQ +I S++ + +EEE E+ +AL ELS Sbjct: 1004 EEIKQLNQEIRDLNESNSEMEAAMVQLQSQISSMEKNLKNIEEENKLIEEQNEALFLELS 1063
>GFAP_HUMAN (P14136) Glial fibrillary acidic protein, astrocyte (GFAP)| Length = 432 Score = 36.6 bits (83), Expect = 0.027 Identities = 36/139 (25%), Positives = 66/139 (47%), Gaps = 6/139 (4%) Frame = +3 Query: 24 EEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHG---ETSKCKDVEASKLMLQKELEM 194 +E S +AEM + L + A EK+R L + E ++ + E +KL + E+ Sbjct: 63 KETRASERAEM--MELNDRFASYIEKVRFLEQQNKALAAELNQLRAKEPTKLADVYQAEL 120 Query: 195 IREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKK---ALQHELSHI 365 RE +LD +S + + + L ++KL++E + +E + A + E Sbjct: 121 -RELRLRLDQLTANSARLEVERDNLAQDLATVRQKLQDETNLRLEAENNLAAYRQEADEA 179 Query: 366 XNDRGDVERKHFSIKEQIQ 422 R D+ERK S++E+I+ Sbjct: 180 TLARLDLERKIESLEEEIR 198
>M4K4_MOUSE (P97820) Mitogen-activated protein kinase kinase kinase kinase 4| (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase) Length = 1233 Score = 36.6 bits (83), Expect = 0.027 Identities = 33/132 (25%), Positives = 60/132 (45%) Frame = +3 Query: 21 QEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIR 200 QE + +S +L E+QL + +E R L E+ + K+ + L+++ R Sbjct: 360 QENKERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKE---QRRRLEEQQRRER 416 Query: 201 EENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHIXNDRG 380 E R+ + + R +E+ +RK EEE R EEK+ ++ E +I Sbjct: 417 EARRQQEREQRRREQEEKRRLEEL----ERRRKEEEERRRAEEEKRRVEREQEYIRRQL- 471 Query: 381 DVERKHFSIKEQ 416 + E++H I +Q Sbjct: 472 EEEQRHLEILQQ 483
>CENPE_HUMAN (Q02224) Centromeric protein E (CENP-E protein)| Length = 2663 Score = 36.6 bits (83), Expect = 0.027 Identities = 33/137 (24%), Positives = 69/137 (50%) Frame = +3 Query: 12 VSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELE 191 VS + ++L +MQ + LE A++QEK++ L +H + KDV + QK++ Sbjct: 1797 VSEKTDKLSNMQKD-----LENSNAKLQEKIQELKANEHQLITLKKDVNET----QKKVS 1847 Query: 192 MIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHIXN 371 + + +++ DQ+ + + + EI +L AQ E+ ++EE K++ E ++ Sbjct: 1848 EMEQLKKQIKDQSLTLSKL------EIENLNLAQ-----ELHENLEEMKSVMKERDNLRR 1896 Query: 372 DRGDVERKHFSIKEQIQ 422 ++ + +KE +Q Sbjct: 1897 VEETLKLERDQLKESLQ 1913 Score = 32.3 bits (72), Expect = 0.51 Identities = 29/122 (23%), Positives = 57/122 (46%), Gaps = 7/122 (5%) Frame = +3 Query: 78 QLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIREENRKLDDQNHSSTSVIIR 257 +LA+V+EKL+ S + + + +V+ +QK++ I EN K + +N T + Sbjct: 1121 RLAEVEEKLKEKSQQLQEKQQQLLNVQEEMSEMQKKINEI--ENLKNELKNKELT--LEH 1176 Query: 258 LQDEIISLKNAQRKLEEEVSRHVEEKKALQH-------ELSHIXNDRGDVERKHFSIKEQ 416 ++ E + L + EEV +E+K L+ E H+ ++E KE+ Sbjct: 1177 METERLELAQKLNENYEEVKSITKERKVLKELQKSFETERDHLRGYIREIEATGLQTKEE 1236 Query: 417 IQ 422 ++ Sbjct: 1237 LK 1238 Score = 28.9 bits (63), Expect = 5.7 Identities = 21/83 (25%), Positives = 38/83 (45%) Frame = +3 Query: 174 LQKELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHE 353 LQ+ LE + E +L + + I Q+E+ L + +K +E V++ + E Sbjct: 1055 LQQMLESVIAEKEQLKTDLKENIEMTIENQEELRLLGDELKKQQEIVAQEKNHAIKKEGE 1114 Query: 354 LSHIXNDRGDVERKHFSIKEQIQ 422 LS + +VE K +Q+Q Sbjct: 1115 LSRTCDRLAEVEEKLKEKSQQLQ 1137 Score = 28.5 bits (62), Expect = 7.4 Identities = 19/81 (23%), Positives = 35/81 (43%) Frame = +3 Query: 96 EKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIREENRKLDDQNHSSTSVIIRLQDEII 275 EK+R L H E+ + +QKELE+ + KL + H S + + ++ I Sbjct: 2343 EKIRELENSLHEAKESAMHKESKIIKMQKELEVTNDIIAKLQAKVHESNKCLEKTKETIQ 2402 Query: 276 SLKNAQRKLEEEVSRHVEEKK 338 L++ + +E+ K Sbjct: 2403 VLQDKVALGAKPYKEEIEDLK 2423
>CLPB_LACLC (O68185) Chaperone clpB| Length = 867 Score = 36.6 bits (83), Expect = 0.027 Identities = 30/132 (22%), Positives = 68/132 (51%), Gaps = 3/132 (2%) Frame = +3 Query: 9 SVSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKL-MLQKE 185 ++ + +E +++ EM SL +L Q +L L +E+ + D +L +++ E Sbjct: 392 AIDLIDEASATIRVEMN--SLPTELDQANRRLMQLEIEEAALKKERDDASKKRLEIIRGE 449 Query: 186 LEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSR-HVEEKKALQH-ELS 359 + +REEN +L Q + + + ++ L++A+ +LEE + ++E+ AL++ ++ Sbjct: 450 IAELREENNQLKAQWEAEKKEVGNISEKRNELEHARHELEEAQNEGNLEKAAALRYGKIP 509 Query: 360 HIXNDRGDVERK 395 I + +E K Sbjct: 510 EIEKELKAIEEK 521
>UBP2_YEAST (Q01476) Ubiquitin carboxyl-terminal hydrolase 2 (EC 3.1.2.15)| (Ubiquitin thioesterase 2) (Ubiquitin-specific-processing protease 2) (Deubiquitinating enzyme 2) Length = 1272 Score = 36.6 bits (83), Expect = 0.027 Identities = 30/126 (23%), Positives = 62/126 (49%), Gaps = 11/126 (8%) Frame = +3 Query: 63 LSLEKQLAQVQEKLR--------LLSLEKHGETSKCKDVEASKLMLQKELEMIREENRKL 218 L+ +K+ ++++KL+ LLS + G T K +E+ KL+ E + I++ K+ Sbjct: 1090 LAKKKETEEMKQKLKVMKNRQRELLSRDDSGLTRKDAFLESIKLL---ESDTIKKTPLKI 1146 Query: 219 DDQNHSSTSV---IIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHIXNDRGDVE 389 + N ++ + + +E++ L N LEE++S ++ K + L + RG+ Sbjct: 1147 EAANDVIKTLRNNVQNIDNELMKLYNDINSLEEKISHQFDDFKEYGYSLFSVFIHRGEAS 1206 Query: 390 RKHFSI 407 H+ I Sbjct: 1207 YGHYWI 1212
>MYH6_MESAU (P13539) Myosin heavy chain, cardiac muscle alpha isoform| (MyHC-alpha) Length = 1939 Score = 36.6 bits (83), Expect = 0.027 Identities = 37/152 (24%), Positives = 62/152 (40%), Gaps = 21/152 (13%) Frame = +3 Query: 6 LSVSIQEEQLKSMQAEMARLSLEKQL--------------AQVQEKLRLLSLEKHGETSK 143 L S+++E+ M E A+ LE L Q++EKL+ + + SK Sbjct: 1036 LEGSLEQEKKVRMDLERAKRKLEGDLNVTQESIMDLENDKLQLEEKLKKKEFDISQQNSK 1095 Query: 144 CKDVEASKLMLQKELE----MIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEE- 308 +D +A L LQK+L+ I E +L+ + + V D L+ +LEE Sbjct: 1096 IEDEQALALQLQKKLKENQARIEELEEELEAERTARAKVEKLRSDLTRELEEISERLEEA 1155 Query: 309 --EVSRHVEEKKALQHELSHIXNDRGDVERKH 398 S +E K + E + D + +H Sbjct: 1156 GGATSVQIEMNKKREAEFQKMRRDLEEATLQH 1187 Score = 34.7 bits (78), Expect = 0.10 Identities = 31/149 (20%), Positives = 65/149 (43%), Gaps = 22/149 (14%) Frame = +3 Query: 6 LSVSIQEEQLKSMQAEMARLSLEKQLAQVQEKL-RLLSLEKHGETSKCKDVEASKLMLQK 182 ++ +++EQ S E + ++E+ + +Q +L + G + + +EA L+ Sbjct: 1767 MAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEN 1826 Query: 183 ELEMIREEN--------------RKLDDQNHSSTSVIIRLQDEIISL-------KNAQRK 299 ELE ++ N ++L Q ++RLQD + L K + Sbjct: 1827 ELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKKNLVRLQDLVDKLQLKVKAYKRQAEE 1886 Query: 300 LEEEVSRHVEEKKALQHELSHIXNDRGDV 386 EE+ + ++ + + +QHEL +R D+ Sbjct: 1887 AEEQANTNLSKFRKVQHELDE-AEERADI 1914 Score = 33.5 bits (75), Expect = 0.23 Identities = 30/143 (20%), Positives = 65/143 (45%) Frame = +3 Query: 3 KLSVSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQK 182 K S+ E + K ++ +M L EK Q Q + +L E +C + +K+ L+ Sbjct: 862 KESLEKSEARRKELEEKMVSLLQEKNDLQFQVQAEQDNLNDAEE--RCDQLIKNKIQLEA 919 Query: 183 ELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSH 362 + ++E +L+D+ + L + +RKLE+E S ++ L+ L+ Sbjct: 920 K---VKEMTERLEDEEEMNAE-----------LTSKKRKLEDECSELKKDIDDLELTLAK 965 Query: 363 IXNDRGDVERKHFSIKEQIQAVN 431 + ++ E K ++ E++ ++ Sbjct: 966 VEKEKHATENKVKNLTEEMAGLD 988 Score = 33.1 bits (74), Expect = 0.30 Identities = 31/144 (21%), Positives = 56/144 (38%), Gaps = 28/144 (19%) Frame = +3 Query: 36 KSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELE-------- 191 ++ + E A+ L ++L +E + ++ +KC +E +K LQ E+E Sbjct: 1384 RTEELEEAKKKLAQRLQDAEEAVEAVN-------AKCSSLEKTKHRLQNEIEDLMVDVER 1436 Query: 192 -----------------MIREENRKLDDQN---HSSTSVIIRLQDEIISLKNAQRKLEEE 311 ++ E +K ++ SS L E+ LKNA + E Sbjct: 1437 SNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEH 1496 Query: 312 VSRHVEEKKALQHELSHIXNDRGD 383 + E K LQ E+S + G+ Sbjct: 1497 LETFKRENKNLQEEISDLTEQLGE 1520 Score = 30.0 bits (66), Expect = 2.5 Identities = 28/126 (22%), Positives = 63/126 (50%), Gaps = 16/126 (12%) Frame = +3 Query: 27 EQLKSMQAEMARLSLEKQLAQV------------QEKLRLLSLEKHGETSKCKDVEASKL 170 E++ + +A+L+ EK+ Q ++K+ L+ K + D+E S L Sbjct: 982 EEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKSKVKLEQQVDDLEGS-L 1040 Query: 171 MLQKELEM-IREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRH---VEEKK 338 +K++ M + RKL+ + + I+ L+++ + L+ +K E ++S+ +E+++ Sbjct: 1041 EQEKKVRMDLERAKRKLEGDLNVTQESIMDLENDKLQLEEKLKKKEFDISQQNSKIEDEQ 1100 Query: 339 ALQHEL 356 AL +L Sbjct: 1101 ALALQL 1106
>TNIK_HUMAN (Q9UKE5) TRAF2 and NCK-interacting kinase (EC 2.7.11.1)| Length = 1360 Score = 36.6 bits (83), Expect = 0.027 Identities = 31/128 (24%), Positives = 55/128 (42%) Frame = +3 Query: 36 KSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIREENRK 215 K + R LE+Q + +E R L E+ QK +E +E+ R+ Sbjct: 362 KERSEALRRQQLEQQQRENEEHKRQLLAER-----------------QKRIEEQKEQRRR 404 Query: 216 LDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHIXNDRGDVERK 395 L++Q +R Q E QR+ EE R EE++ +HE +I + +R+ Sbjct: 405 LEEQQRREKE--LRKQQE-----REQRRHYEEQMRREEERRRAEHEQEYIRRQLEEEQRQ 457 Query: 396 HFSIKEQI 419 +++Q+ Sbjct: 458 LEILQQQL 465
>CASP_MOUSE (P70403) Protein CASP| Length = 678 Score = 36.6 bits (83), Expect = 0.027 Identities = 38/161 (23%), Positives = 81/161 (50%), Gaps = 21/161 (13%) Frame = +3 Query: 12 VSIQEEQLKSMQAEMARL-----SLEKQLAQVQ-EKLRLLSL-EKHGETSKCKDVEASKL 170 + I+ ++L ++ E +L K+ A+V+ +++ + +L EK E + +A + Sbjct: 112 LEIKVQRLHDIETENQKLRETLEEYNKEFAEVKNQEVTIKALKEKIREYEQTLKSQAETI 171 Query: 171 MLQKELEM---IREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEV----SRHVE 329 L+KE ++ E+ RKL + S+TS + + ++ +L+ A K E+ +++ E Sbjct: 172 ALEKEQKLQNDFAEKERKLQETQMSTTSKLEEAEHKLQTLQTALEKTRTELFDLKTKYDE 231 Query: 330 EKKALQHELSHI------XNDRGDV-ERKHFSIKEQIQAVN 431 E A E+ I N R +V +R+ +++EQ+ + N Sbjct: 232 ETTAKADEIEMIMTDLERANQRAEVAQREAETLREQLSSAN 272
>MYO1_CAEEL (P02567) Myosin-1 (Myosin heavy chain D) (MHC D)| Length = 1938 Score = 36.6 bits (83), Expect = 0.027 Identities = 38/146 (26%), Positives = 67/146 (45%), Gaps = 8/146 (5%) Frame = +3 Query: 18 IQEEQLKSMQAEMARLSLEKQLAQVQEKL-RLLSLEKHGETSKCKDVEASKLMLQK---E 185 +Q E+ K QA R LE+ L +++E + R + E SK K VE Q+ E Sbjct: 1017 LQAEEAKQAQANRLRGKLEQTLDEMEEAVEREKRIRAETEKSKRK-VEGELKGAQETIDE 1075 Query: 186 LEMIR-EENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHE--- 353 L I+ E + L + ++ +R++DE R+ +E R +E + L+HE Sbjct: 1076 LSAIKLETDASLKKKEADIHALGVRIEDEQALANRLTRQSKENAQRIIEIEDELEHERQS 1135 Query: 354 LSHIXNDRGDVERKHFSIKEQIQAVN 431 S R +++R+ + E++ N Sbjct: 1136 RSKADRARAELQRELDELNERLDEQN 1161 Score = 30.0 bits (66), Expect = 2.5 Identities = 32/153 (20%), Positives = 69/153 (45%), Gaps = 25/153 (16%) Frame = +3 Query: 3 KLSVSIQEEQLKSMQAEMARLSLE----------------------KQLAQVQEKLRLLS 116 +L+ +++EQ ++ + R SLE K LA+V++++R L Sbjct: 1771 RLAEEVRQEQEHAVHVDRQRKSLELNAKELQAKIDDAERAMIQFGAKALAKVEDRVRSLE 1830 Query: 117 LEKHGETSKCKDV---EASKLMLQKELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKN 287 E H E + ++ + +EL+ EE++K D+ + + +LQ +I K Sbjct: 1831 AELHSEQRRHQESIKGYTKQERRARELQFQVEEDKKAFDRLQEN---VEKLQQKIRVQKR 1887 Query: 288 AQRKLEEEVSRHVEEKKALQHELSHIXNDRGDV 386 + EE ++++ + + +Q L + +R +V Sbjct: 1888 QIEEAEEVATQNLSKFRQIQLALEN-AEERAEV 1919 Score = 28.9 bits (63), Expect = 5.7 Identities = 20/119 (16%), Positives = 54/119 (45%) Frame = +3 Query: 72 EKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIREENRKLDDQNHSSTSVI 251 ++++ +Q+++ + + +++ + +S L +++E +R EN+ + I Sbjct: 1464 KRKVDDIQKEIDATTRDSRNTSTEVFKLRSSMDNLSEQIETLRRENKIFSQE-------I 1516 Query: 252 IRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHIXNDRGDVERKHFSIKEQIQAV 428 + ++I +++ + V R +EK LQH L E K ++ ++Q + Sbjct: 1517 RDINEQITQGGRTYQEVHKSVRRLEQEKDELQHALDEAEAALEAEESKVLRLQIEVQQI 1575
>MYH6_RAT (P02563) Myosin heavy chain, cardiac muscle alpha isoform| (MyHC-alpha) Length = 1938 Score = 36.6 bits (83), Expect = 0.027 Identities = 34/132 (25%), Positives = 56/132 (42%), Gaps = 7/132 (5%) Frame = +3 Query: 24 EEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELE---- 191 E LK Q + + LE Q++EKL+ + + SK +D +A L LQK+L+ Sbjct: 1057 EGDLKLTQESI--MDLENDKLQLEEKLKKKEFDISQQNSKIEDEQALALQLQKKLKENQA 1114 Query: 192 MIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEE---EVSRHVEEKKALQHELSH 362 I E +L+ + + V D L+ +LEE S +E K + E Sbjct: 1115 RIEELEEELEAERTARAKVEKLRSDLTRELEEISERLEEAGGATSVQIEMNKKREAEFQK 1174 Query: 363 IXNDRGDVERKH 398 + D + +H Sbjct: 1175 MRRDLEEATLQH 1186 Score = 34.7 bits (78), Expect = 0.10 Identities = 31/149 (20%), Positives = 65/149 (43%), Gaps = 22/149 (14%) Frame = +3 Query: 6 LSVSIQEEQLKSMQAEMARLSLEKQLAQVQEKL-RLLSLEKHGETSKCKDVEASKLMLQK 182 ++ +++EQ S E + ++E+ + +Q +L + G + + +EA L+ Sbjct: 1766 MAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEN 1825 Query: 183 ELEMIREEN--------------RKLDDQNHSSTSVIIRLQDEIISL-------KNAQRK 299 ELE ++ N ++L Q ++RLQD + L K + Sbjct: 1826 ELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKKNLVRLQDLVDKLQLKVKAYKRQAEE 1885 Query: 300 LEEEVSRHVEEKKALQHELSHIXNDRGDV 386 EE+ + ++ + + +QHEL +R D+ Sbjct: 1886 AEEQANTNLSKFRKVQHELDE-AEERADI 1913 Score = 33.1 bits (74), Expect = 0.30 Identities = 31/144 (21%), Positives = 56/144 (38%), Gaps = 28/144 (19%) Frame = +3 Query: 36 KSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELE-------- 191 ++ + E A+ L ++L +E + ++ +KC +E +K LQ E+E Sbjct: 1383 RTEELEEAKKKLAQRLQDAEEAVEAVN-------AKCSSLEKTKHRLQNEIEDLMVDVER 1435 Query: 192 -----------------MIREENRKLDDQN---HSSTSVIIRLQDEIISLKNAQRKLEEE 311 ++ E +K ++ SS L E+ LKNA + E Sbjct: 1436 SNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEH 1495 Query: 312 VSRHVEEKKALQHELSHIXNDRGD 383 + E K LQ E+S + G+ Sbjct: 1496 LETFKRENKNLQEEISDLTEQLGE 1519 Score = 31.6 bits (70), Expect = 0.87 Identities = 27/136 (19%), Positives = 63/136 (46%) Frame = +3 Query: 24 EEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIRE 203 E + K ++ +M L EK Q+Q + +L E +C + +K+ L+ + ++E Sbjct: 868 EARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEE--RCDQLIKNKIQLEAK---VKE 922 Query: 204 ENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHIXNDRGD 383 +L+D+ + + + +RKLE+E S ++ L+ L+ + ++ Sbjct: 923 MTERLEDEEEMNAELTAK-----------KRKLEDECSELKKDIDDLELTLAKVEKEKHA 971 Query: 384 VERKHFSIKEQIQAVN 431 E K ++ E++ ++ Sbjct: 972 TENKVKNLTEEMAGLD 987 Score = 29.3 bits (64), Expect = 4.3 Identities = 28/126 (22%), Positives = 62/126 (49%), Gaps = 16/126 (12%) Frame = +3 Query: 27 EQLKSMQAEMARLSLEKQLAQV------------QEKLRLLSLEKHGETSKCKDVEASKL 170 E++ + +A+L+ EK+ Q ++K+ L+ K + D+E S L Sbjct: 981 EEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKSKVKLEQQVDDLEGS-L 1039 Query: 171 MLQKELEM-IREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRH---VEEKK 338 +K++ M + RKL+ + I+ L+++ + L+ +K E ++S+ +E+++ Sbjct: 1040 EQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDISQQNSKIEDEQ 1099 Query: 339 ALQHEL 356 AL +L Sbjct: 1100 ALALQL 1105
>CUTL1_MOUSE (P53564) Homeobox protein cut-like 1 (CCAAT displacement protein)| (CDP) (Homeobox protein Cux) Length = 1515 Score = 36.6 bits (83), Expect = 0.027 Identities = 38/161 (23%), Positives = 81/161 (50%), Gaps = 21/161 (13%) Frame = +3 Query: 12 VSIQEEQLKSMQAEMARL-----SLEKQLAQVQ-EKLRLLSL-EKHGETSKCKDVEASKL 170 + I+ ++L ++ E +L K+ A+V+ +++ + +L EK E + +A + Sbjct: 101 LEIKVQRLHDIETENQKLRETLEEYNKEFAEVKNQEVTIKALKEKIREYEQTLKSQAETI 160 Query: 171 MLQKELEM---IREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEV----SRHVE 329 L+KE ++ E+ RKL + S+TS + + ++ +L+ A K E+ +++ E Sbjct: 161 ALEKEQKLQNDFAEKERKLQETQMSTTSKLEEAEHKLQTLQTALEKTRTELFDLKTKYDE 220 Query: 330 EKKALQHELSHI------XNDRGDV-ERKHFSIKEQIQAVN 431 E A E+ I N R +V +R+ +++EQ+ + N Sbjct: 221 ETTAKADEIEMIMTDLERANQRAEVAQREAETLREQLSSAN 261
>CN145_MOUSE (Q8BI22) Protein C14orf145 homolog| Length = 524 Score = 36.6 bits (83), Expect = 0.027 Identities = 35/165 (21%), Positives = 70/165 (42%), Gaps = 26/165 (15%) Frame = +3 Query: 3 KLSVSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQK 182 K+ + +E +K + A R L +LA+ ++ + + + T++ K E Sbjct: 124 KVKLLEMQESIKDLSA--IRADLANKLAEEEKAKKAVFRDLSELTAQVKSKEEETATAIT 181 Query: 183 ELEMIRE-ENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKA------ 341 +L++ R+ R+L+D + S SV ++ + I L +K + E H+ KA Sbjct: 182 QLKLERDVHQRELEDLSSSLESVKLKHEQNIQELMKHFKKEKSEAESHIRMLKAESLEDK 241 Query: 342 -------------------LQHELSHIXNDRGDVERKHFSIKEQI 419 L EL+H N+ ++ K+ S+KE++ Sbjct: 242 NMAKAHLGQLEKLKSQCEKLTEELTHTENENKKLKLKYQSLKEEL 286 Score = 30.8 bits (68), Expect = 1.5 Identities = 29/128 (22%), Positives = 59/128 (46%) Frame = +3 Query: 15 SIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEM 194 S + Q+K+ + + E + +Q Q+K++LL +++ KD+ A + L +L Sbjct: 96 SKSQSQIKAEKIHLEEEITELKKSQSQDKVKLLEMQE-----SIKDLSAIRADLANKLAE 150 Query: 195 IREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHIXND 374 E+ +K ++ S + ++ ++E + Q KLE +V Q EL + + Sbjct: 151 -EEKAKKAVFRDLSELTAQVKSKEEETATAITQLKLERDVH---------QRELEDLSSS 200 Query: 375 RGDVERKH 398 V+ KH Sbjct: 201 LESVKLKH 208
>BEGIN_SHEEP (Q6R6L0) Brain-enriched guanylate kinase-associated protein| Length = 653 Score = 36.2 bits (82), Expect = 0.035 Identities = 32/133 (24%), Positives = 65/133 (48%), Gaps = 12/133 (9%) Frame = +3 Query: 30 QLKSMQAEMARLSLEKQLAQVQEKL----RLLSLEKHGETSKCKDVEASKLMLQKELEMI 197 Q +++Q AR S + +QE+ + LS H + ++++ L+ EL Sbjct: 36 QSRNLQGRRARSSPSLWDSSLQEQKGELRKRLSYTTHRLEKLENEFDSTRHFLEIELRRA 95 Query: 198 REENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSR----HVEEKKALQHEL--- 356 +EE K+ T + R+Q ++L+ ++LE+++ R + EEK+AL HE+ Sbjct: 96 QEELEKV-------TEKLRRIQSNYMALQRINQELEDKLFRMGQHYEEEKRALSHEIVAL 148 Query: 357 -SHIXNDRGDVER 392 SH+ + +++ Sbjct: 149 NSHLLEAKVTIDK 161
>YNJ1_YEAST (P53935) Hypothetical 141.5 kDa protein in YPT53-RHO2 intergenic| region Length = 1240 Score = 36.2 bits (82), Expect = 0.035 Identities = 33/126 (26%), Positives = 60/126 (47%) Frame = +3 Query: 45 QAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIREENRKLDD 224 QA+ RL L ++L + + K R EK + K ++ E K LQ+ + EE RK ++ Sbjct: 619 QADNNRLKLLQELEEEKRKKR----EKEEKKQKKREKEKEKKRLQQLAK--EEEKRKREE 672 Query: 225 QNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHIXNDRGDVERKHFS 404 + L++ + + AQRK EE R +E++ + E + + +RK Sbjct: 673 EKERLKK---ELEEREMRRREAQRKKVEEAKRKKDEERKRRLEEQQRREEMQEKQRKQ-- 727 Query: 405 IKEQIQ 422 KE+++ Sbjct: 728 -KEELK 732 Score = 33.9 bits (76), Expect = 0.18 Identities = 39/156 (25%), Positives = 68/156 (43%), Gaps = 16/156 (10%) Frame = +3 Query: 3 KLSVSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQK 182 KL ++EE+ K + E + +K+ + +EK RL L K E K E K L+K Sbjct: 626 KLLQELEEEKRKKREKEEKK---QKKREKEKEKKRLQQLAKEEEKRKR---EEEKERLKK 679 Query: 183 ELE------------MIREENRKLDDQNHSSTSVIIRLQD----EIISLKNAQRKLEEEV 314 ELE + E RK D++ R ++ + + +RK EEE Sbjct: 680 ELEEREMRRREAQRKKVEEAKRKKDEERKRRLEEQQRREEMQEKQRKQKEELKRKREEEK 739 Query: 315 SRHVEEKKALQHELSHIXNDRGDVERKHFSIKEQIQ 422 R E+K+ Q +L ++ + ER+ ++ ++ Sbjct: 740 KRIREQKRLEQEKLQ---KEKEEEERQRLIAEDALR 772 Score = 28.9 bits (63), Expect = 5.7 Identities = 21/83 (25%), Positives = 39/83 (46%) Frame = +3 Query: 147 KDVEASKLMLQKELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHV 326 K + ++L L +ELE + + R+ +++ + + E + Q EEE + Sbjct: 618 KQADNNRLKLLQELEEEKRKKREKEEKKQK------KREKEKEKKRLQQLAKEEEKRKRE 671 Query: 327 EEKKALQHELSHIXNDRGDVERK 395 EEK+ L+ EL R + +RK Sbjct: 672 EEKERLKKELEEREMRRREAQRK 694
>ITSN1_RAT (Q9WVE9) Intersectin-1 (EH domain and SH3 domain regulator of| endocytosis 1) Length = 1217 Score = 36.2 bits (82), Expect = 0.035 Identities = 32/132 (24%), Positives = 61/132 (46%), Gaps = 7/132 (5%) Frame = +3 Query: 21 QEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIR 200 ++EQ + Q E A +++ Q QE+ R L LEK +L Q+ELE R Sbjct: 376 RKEQERLAQLERAEQERKERERQEQERKRQLELEK-------------QLEKQRELERQR 422 Query: 201 EENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVE-------EKKALQHELS 359 EE R+ + + + + Q ++ +N +++L + ++ E +K L+ EL Sbjct: 423 EEERRKEIERREAAKRELERQRQLEWERNRRQELLTQRNKDQEGIVVLKARRKTLEFELE 482 Query: 360 HIXNDRGDVERK 395 + + + +E K Sbjct: 483 ALNDKKHQLEGK 494
>CCD13_HUMAN (Q8IYE1) Coiled-coil domain-containing protein 13| Length = 715 Score = 36.2 bits (82), Expect = 0.035 Identities = 31/107 (28%), Positives = 56/107 (52%), Gaps = 8/107 (7%) Frame = +3 Query: 15 SIQEEQLKSMQAEMAR-----LSLEKQLAQVQEKLRL---LSLEKHGETSKCKDVEASKL 170 ++QE Q K +Q +M + LSL+ + +E L + LSL GE + E K Sbjct: 17 AMQEMQHKRLQKQMEKKREKELSLKSRADDQEEPLEVSDGLSLLHAGEPNSKNSFE--KR 74 Query: 171 MLQKELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEE 311 +L+ E+E +R E R+ D+N + L++ +K+ ++K+EE+ Sbjct: 75 VLEDEIEHLRNELRETVDENGRLYKL---LKERDFEIKHLKKKIEED 118
>LMNA_CHICK (P13648) Lamin-A| Length = 657 Score = 36.2 bits (82), Expect = 0.035 Identities = 28/134 (20%), Positives = 60/134 (44%) Frame = +3 Query: 21 QEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIR 200 + E++ S + + + E +LA ++ L ++ E+ LQ EL +R Sbjct: 64 ESEEVVSREVSGIKAAYEAELADARKTLDSVAKER--------------ARLQLELSKVR 109 Query: 201 EENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHIXNDRG 380 EE+++L +N + ++ Q + L+ E +S + EK+ L++E+ + Sbjct: 110 EEHKELKARNAKKEADLLAAQARLKDLEALLNSKEAALSTALGEKRNLENEVRDLRAQVA 169 Query: 381 DVERKHFSIKEQIQ 422 +E K+Q+Q Sbjct: 170 KLEGALSEAKKQLQ 183
>CALD1_CHICK (P12957) Caldesmon (CDM)| Length = 771 Score = 36.2 bits (82), Expect = 0.035 Identities = 30/135 (22%), Positives = 56/135 (41%) Frame = +3 Query: 21 QEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIR 200 ++E+ K E RL E++ +EK + +K E + E K ++ Sbjct: 249 EKEREKLEAEEKERLKAEEEKKAAEEKQKAEEEKKAAEERERAKAEEEKRAAEERERAKA 308 Query: 201 EENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHIXNDRG 380 EE RK ++ + + R E + +RK EE ++ EE+KA + + Sbjct: 309 EEERKAAEERERAKAEEERKAAEERAKAEEERKAAEERAKAEEERKAAEERAKAEKERKA 368 Query: 381 DVERKHFSIKEQIQA 425 ER+ +E+ +A Sbjct: 369 AEERERAKAEEEKRA 383
>LUZP1_RAT (Q9ESV1) Leucine zipper protein 1 (Leucine zipper motif-containing| protein) Length = 1051 Score = 36.2 bits (82), Expect = 0.035 Identities = 41/165 (24%), Positives = 75/165 (45%), Gaps = 25/165 (15%) Frame = +3 Query: 3 KLSVSIQEEQLKSMQAEMARLSLEK---QLAQVQEKLRLLSLEKHGETSKCKDVEASKLM 173 K+S ++ ++K + E + LEK L EKL+ L+L E + E Sbjct: 150 KISSELEMLRVKVKELESSEDRLEKTEQSLVSELEKLKSLTLSFVNERKYLNEKEKENEK 209 Query: 174 LQKELEMIREENRKLDDQNHSSTSVI-----IRLQDEIISL---KNAQRK--------LE 305 L KEL E+N+K++ + + S +R++D I S K ++RK +E Sbjct: 210 LIKELTQKLEQNKKINRDHMRNASTFLERNDLRIEDGISSTLPSKESRRKGSLDYLKQVE 269 Query: 306 EEVSRHVEEKKALQHELSHIXNDRGDVER-----KHF-SIKEQIQ 422 E E +K E + + + ++E+ KHF S++E+++ Sbjct: 270 NETRDKSENEKNRNQEDNKVKDLNQEIEKLKTQIKHFESLEEELK 314
>HMMR_HUMAN (O75330) Hyaluronan mediated motility receptor (Intracellular| hyaluronic acid-binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen) Length = 724 Score = 36.2 bits (82), Expect = 0.035 Identities = 30/115 (26%), Positives = 54/115 (46%), Gaps = 9/115 (7%) Frame = +3 Query: 36 KSMQAEMARLSLEKQLAQVQEKLRLLSLEKHG----ETSKCKDVEASKLMLQKELEMIRE 203 K Q ++ +EKQ L +HG + +K +D A KL+ + L+ + Sbjct: 591 KPFQLQLDAFEVEKQAL----------LNEHGAAQEQLNKIRDSYA-KLLGHQNLKQKIK 639 Query: 204 ENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVS-----RHVEEKKALQHE 353 KL D+N S + +L+ ++ K ++ KL+EE++ +H + KA HE Sbjct: 640 HVVKLKDENSQLKSEVSKLRCQLAKKKQSETKLQEELNKVLGIKHFDPSKAFHHE 694 Score = 31.2 bits (69), Expect = 1.1 Identities = 34/130 (26%), Positives = 56/130 (43%), Gaps = 2/130 (1%) Frame = +3 Query: 15 SIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKD--VEASKLMLQKEL 188 S++E Q K Q E +S+EK+ ++ EK L ++ E C VE KL + + Sbjct: 201 SLEESQGKIAQLEGKLVSIEKE--KIDEKSETEKLLEYIEEISCASDQVEKYKLDIAQLE 258 Query: 189 EMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHIX 368 E ++E+N DEI+SLK + + +S+ VE+ L Sbjct: 259 ENLKEKN------------------DEILSLKQSLEENIVILSKQVEDLNVKCQLLEKEK 300 Query: 369 NDRGDVERKH 398 D + R+H Sbjct: 301 EDHVNRNREH 310
>TPM1_RAT (P04692) Tropomyosin 1 alpha chain (Alpha-tropomyosin)| Length = 284 Score = 36.2 bits (82), Expect = 0.035 Identities = 25/113 (22%), Positives = 51/113 (45%) Frame = +3 Query: 90 VQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIREENRKLDDQNHSSTSVIIRLQDE 269 +++K+++L L+K + + EA K + +D++ +L+DE Sbjct: 4 IKKKMQMLKLDKENALDRAEQAEADK--------------KAAEDRSK-------QLEDE 42 Query: 270 IISLKNAQRKLEEEVSRHVEEKKALQHELSHIXNDRGDVERKHFSIKEQIQAV 428 ++SL+ + E+E+ ++ E K Q +L D E S+ +IQ V Sbjct: 43 LVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLV 95 Score = 33.5 bits (75), Expect = 0.23 Identities = 27/108 (25%), Positives = 51/108 (47%) Frame = +3 Query: 51 EMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIREENRKLDDQN 230 E A LS E + A+++E+L+ + T+ K +EA ++ + EE + L D+ Sbjct: 181 ERAELS-EGKCAELEEELKTV-------TNNLKSLEAQAEKYSQKEDKYEEEIKVLSDKL 232 Query: 231 HSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHIXND 374 + + + + L+ + LE+E+ + KA+ EL H ND Sbjct: 233 KEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALND 280
>TPM1_RABIT (P58772) Tropomyosin 1 alpha chain (Alpha-tropomyosin)| Length = 284 Score = 36.2 bits (82), Expect = 0.035 Identities = 25/113 (22%), Positives = 51/113 (45%) Frame = +3 Query: 90 VQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIREENRKLDDQNHSSTSVIIRLQDE 269 +++K+++L L+K + + EA K + +D++ +L+DE Sbjct: 4 IKKKMQMLKLDKENALDRAEQAEADK--------------KAAEDRSK-------QLEDE 42 Query: 270 IISLKNAQRKLEEEVSRHVEEKKALQHELSHIXNDRGDVERKHFSIKEQIQAV 428 ++SL+ + E+E+ ++ E K Q +L D E S+ +IQ V Sbjct: 43 LVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLV 95 Score = 33.5 bits (75), Expect = 0.23 Identities = 27/108 (25%), Positives = 51/108 (47%) Frame = +3 Query: 51 EMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIREENRKLDDQN 230 E A LS E + A+++E+L+ + T+ K +EA ++ + EE + L D+ Sbjct: 181 ERAELS-EGKCAELEEELKTV-------TNNLKSLEAQAEKYSQKEDKYEEEIKVLSDKL 232 Query: 231 HSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHIXND 374 + + + + L+ + LE+E+ + KA+ EL H ND Sbjct: 233 KEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALND 280
>TPM1_MOUSE (P58771) Tropomyosin 1 alpha chain (Alpha-tropomyosin)| Length = 284 Score = 36.2 bits (82), Expect = 0.035 Identities = 25/113 (22%), Positives = 51/113 (45%) Frame = +3 Query: 90 VQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIREENRKLDDQNHSSTSVIIRLQDE 269 +++K+++L L+K + + EA K + +D++ +L+DE Sbjct: 4 IKKKMQMLKLDKENALDRAEQAEADK--------------KAAEDRSK-------QLEDE 42 Query: 270 IISLKNAQRKLEEEVSRHVEEKKALQHELSHIXNDRGDVERKHFSIKEQIQAV 428 ++SL+ + E+E+ ++ E K Q +L D E S+ +IQ V Sbjct: 43 LVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLV 95 Score = 33.5 bits (75), Expect = 0.23 Identities = 27/108 (25%), Positives = 51/108 (47%) Frame = +3 Query: 51 EMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIREENRKLDDQN 230 E A LS E + A+++E+L+ + T+ K +EA ++ + EE + L D+ Sbjct: 181 ERAELS-EGKCAELEEELKTV-------TNNLKSLEAQAEKYSQKEDKYEEEIKVLSDKL 232 Query: 231 HSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHIXND 374 + + + + L+ + LE+E+ + KA+ EL H ND Sbjct: 233 KEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALND 280
>TPM1_HUMAN (P09493) Tropomyosin 1 alpha chain (Alpha-tropomyosin)| Length = 284 Score = 36.2 bits (82), Expect = 0.035 Identities = 25/113 (22%), Positives = 51/113 (45%) Frame = +3 Query: 90 VQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIREENRKLDDQNHSSTSVIIRLQDE 269 +++K+++L L+K + + EA K + +D++ +L+DE Sbjct: 4 IKKKMQMLKLDKENALDRAEQAEADK--------------KAAEDRSK-------QLEDE 42 Query: 270 IISLKNAQRKLEEEVSRHVEEKKALQHELSHIXNDRGDVERKHFSIKEQIQAV 428 ++SL+ + E+E+ ++ E K Q +L D E S+ +IQ V Sbjct: 43 LVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLV 95 Score = 33.5 bits (75), Expect = 0.23 Identities = 27/108 (25%), Positives = 51/108 (47%) Frame = +3 Query: 51 EMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIREENRKLDDQN 230 E A LS E + A+++E+L+ + T+ K +EA ++ + EE + L D+ Sbjct: 181 ERAELS-EGKCAELEEELKTV-------TNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKL 232 Query: 231 HSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHIXND 374 + + + + L+ + LE+E+ + KA+ EL H ND Sbjct: 233 KEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALND 280
>SNX23_HUMAN (Q96L93) Kinesin-like motor protein C20orf23 (Sorting nexin 23)| Length = 1317 Score = 36.2 bits (82), Expect = 0.035 Identities = 33/144 (22%), Positives = 65/144 (45%), Gaps = 9/144 (6%) Frame = +3 Query: 24 EEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGET---------SKCKDVEASKLML 176 EE+ KS +AE+ R+ E + + + ++ L + K E+ +K KD+ A K Sbjct: 620 EEKQKSDKAELERMQQEVETQRKETEIVQLQIRKQEESLKRRSFHIENKLKDLLAEKEKF 679 Query: 177 QKELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHEL 356 ++E +RE+ + +R+Q+E+ LK + E + +E LQ E Sbjct: 680 EEE--RLREQQEIELQKKRQEEETFLRVQEELQRLKELNNNEKAEKFQIFQELDQLQKEK 737 Query: 357 SHIXNDRGDVERKHFSIKEQIQAV 428 + ++E+K +E+ Q + Sbjct: 738 DE-QYAKLELEKKRLEEQEKEQVM 760
>BRE1_ASHGO (Q757D9) Ubiquitin-protein ligase BRE1 (EC 6.3.2.-)| Length = 643 Score = 36.2 bits (82), Expect = 0.035 Identities = 33/149 (22%), Positives = 69/149 (46%), Gaps = 13/149 (8%) Frame = +3 Query: 3 KLSVSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLL--------SLEKHGET-SKCKDV 155 K S + +E L S + +K A ++ K +L +L K E + KD+ Sbjct: 410 KYSEYVNQESLMSKLTVEKTKADQKYFAAMRSKDSILIENKNLSKNLSKSNELIQQLKDI 469 Query: 156 EASKLM----LQKELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRH 323 E S L K+L + R ++L D N +++ I+ L ++ + +++E ++ Sbjct: 470 EKSLQAKIENLNKQLHISRINEKRLLDSNKTTSLKIMDLTSQLSKANKSSTLVQQECNKL 529 Query: 324 VEEKKALQHELSHIXNDRGDVERKHFSIK 410 +EEK ++ +L+ + ++E K+ + K Sbjct: 530 IEEKAKMESKLNDL-----EIETKNLATK 553
>MYSU_RABIT (Q99105) Myosin heavy chain, embryonic smooth muscle isoform| (Fragment) Length = 501 Score = 36.2 bits (82), Expect = 0.035 Identities = 26/147 (17%), Positives = 69/147 (46%), Gaps = 7/147 (4%) Frame = +3 Query: 3 KLSVSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQK 182 +L +++E+ + A ++ +E L ++ ++ + + + + ++A Q+ Sbjct: 125 ELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARERRVKQLRRLQAQMKDYQR 184 Query: 183 ELEMIREENRKLDDQNHSST-------SVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKA 341 ELE R ++ Q+ S + I++LQ+E+ S + A+R E+E +E Sbjct: 185 ELEEARGSRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEIAN 244 Query: 342 LQHELSHIXNDRGDVERKHFSIKEQIQ 422 S + +++ +E + ++E+++ Sbjct: 245 SASGKSALLDEKRRLEARMRQLEEELE 271 Score = 35.8 bits (81), Expect = 0.046 Identities = 27/118 (22%), Positives = 59/118 (50%), Gaps = 1/118 (0%) Frame = +3 Query: 45 QAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIREENRKLDD 224 +A A+ E+Q Q++ + L K ++E SK L++++E +R + +L+D Sbjct: 19 EALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELED 78 Query: 225 QNHSSTSVIIRLQDEIISLK-NAQRKLEEEVSRHVEEKKALQHELSHIXNDRGDVERK 395 + ++ +RL+ ++K +R L+ + E+K+ L ++ + + D ERK Sbjct: 79 ELQATEDAKLRLEVNTQAMKAQFERDLQARDEQSEEKKRLLTKQVRELEAELED-ERK 135
>MYO2_CAEEL (P12845) Myosin-2 (Myosin heavy chain C) (MHC C)| Length = 1947 Score = 36.2 bits (82), Expect = 0.035 Identities = 30/109 (27%), Positives = 55/109 (50%), Gaps = 6/109 (5%) Frame = +3 Query: 24 EEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIRE 203 EE++ +M + +++LE +LA +KL + + K VEA L+K + + Sbjct: 918 EERMTAMNEQ--KVALEGKLADASKKLEVEEARAVEINKQKKLVEAECADLKKNCQDVDL 975 Query: 204 ENRKLDDQNHSSTSVI------IRLQDEIISLKNAQRKLEEEVSRHVEE 332 RK++ + ++ I +R QDE IS N +RK +EE ++ + E Sbjct: 976 SLRKVEAEKNAKEHQIRALQDEMRQQDENISKLNKERKNQEEQNKKLTE 1024
>BEGIN_HUMAN (Q9BUH8) Brain-enriched guanylate kinase-associated protein| Length = 593 Score = 36.2 bits (82), Expect = 0.035 Identities = 32/130 (24%), Positives = 63/130 (48%), Gaps = 8/130 (6%) Frame = +3 Query: 27 EQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIREE 206 E+L ++Q + L K+L+ KL L E ++++ L+ EL +EE Sbjct: 2 EKLSALQEQKGEL--RKRLSYTTHKLEKLETE----------FDSTRHYLEIELRRAQEE 49 Query: 207 NRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSR----HVEEKKALQHEL----SH 362 K+ T + R+Q ++L+ ++LE+++ R + EEK+AL HE+ SH Sbjct: 50 LEKV-------TEKLRRIQSNYMALQRINQELEDKLYRMGQHYEEEKRALSHEIVALNSH 102 Query: 363 IXNDRGDVER 392 + + +++ Sbjct: 103 LLEAKVTIDK 112
>PLEC1_RAT (P30427) Plectin-1 (PLTN) (PCN)| Length = 4687 Score = 36.2 bits (82), Expect = 0.035 Identities = 33/144 (22%), Positives = 67/144 (46%), Gaps = 7/144 (4%) Frame = +3 Query: 18 IQEEQLKSMQAEMARLSLE-----KQLAQVQEKLRLLSLEKHGETSKCKDVEA--SKLML 176 ++ QLK+ +A RL E K LAQ + + E+ + +A + + Sbjct: 1771 LERWQLKANEALRLRLQAEEVAQQKSLAQADAEKQKEEAEREARRRGKAEEQAVRQRELA 1830 Query: 177 QKELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHEL 356 ++ELE R+ Q ++ +IRL+ E ++ ++ LEEE++R LQHE Sbjct: 1831 EQELEKQRQLTEGTAQQRLAAEQELIRLRAETEQGEHQRQLLEEELAR-------LQHEA 1883 Query: 357 SHIXNDRGDVERKHFSIKEQIQAV 428 + R ++E + ++ +++ + Sbjct: 1884 TAATQKRQELEAELAKVRAEMEVL 1907 Score = 33.9 bits (76), Expect = 0.18 Identities = 30/147 (20%), Positives = 69/147 (46%), Gaps = 9/147 (6%) Frame = +3 Query: 3 KLSVSIQEEQLKSMQAEMARLS---------LEKQLAQVQEKLRLLSLEKHGETSKCKDV 155 +L +S + E+LK AEM+R KQ ++ EKL L + + + + Sbjct: 2515 QLEMSAEAERLKLRMAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTL 2574 Query: 156 EASKLMLQKELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEK 335 E + ++ E +RE +L+ + ++ + +++ LK+ + + ++ + ++E Sbjct: 2575 EIQRQQSDQDAERLREAIAELEREKEK-----LKQEAKLLQLKSEEMQTVQQ-EQILQET 2628 Query: 336 KALQHELSHIXNDRGDVERKHFSIKEQ 416 +ALQ S + ++R+ F +E+ Sbjct: 2629 QALQK--SFLSEKDSLLQRERFIEQEK 2653 Score = 32.7 bits (73), Expect = 0.39 Identities = 35/164 (21%), Positives = 72/164 (43%), Gaps = 24/164 (14%) Frame = +3 Query: 9 SVSIQEEQLKSMQAEMARLS------LEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKL 170 SV + L++ +E+ L+ + + L +++E+ RL ++ E + +VEA+ Sbjct: 1451 SVIQEYVDLRTRYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAA-- 1508 Query: 171 MLQKELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVE------- 329 L+K+ ++ + H+ L+ + QR+++EEV+R E Sbjct: 1509 -LEKQRQLA---------EAHAQAKAQAELE-----ARELQRRMQEEVTRREEAAVDAQQ 1553 Query: 330 EKKALQHELSHIXNDR-----------GDVERKHFSIKEQIQAV 428 +K+++Q EL H+ ER I+E+I+ V Sbjct: 1554 QKRSIQEELQHLRQSSEAEIQAKAQQVEAAERSRMRIEEEIRVV 1597 Score = 29.3 bits (64), Expect = 4.3 Identities = 25/116 (21%), Positives = 61/116 (52%), Gaps = 3/116 (2%) Frame = +3 Query: 3 KLSVSIQEEQLKS-MQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQ 179 ++ V+++ Q + ++ + R S ++ AQ++ L+ E+H ++ ++ + Q Sbjct: 1702 QVQVALETAQRSAEVELQSKRPSFAEKTAQLERTLQ----EEHVTVTQLREEAERRAQQQ 1757 Query: 180 KELEMIREE-NRKLDD-QNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKA 341 E E REE R+L+ Q ++ ++ +RLQ E ++ + + + + E + E++A Sbjct: 1758 AEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQADAEKQKEEAEREA 1813 Score = 28.9 bits (63), Expect = 5.7 Identities = 32/129 (24%), Positives = 58/129 (44%), Gaps = 18/129 (13%) Frame = +3 Query: 21 QEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGE-TSKC-----------KDVEAS 164 ++EQ++++ ++ + E+ QEK L +E+HGE +C KD E Sbjct: 1369 RQEQIQAVPIANSQAAREQLR---QEKALLEEIERHGEKVEECQKFAKQYINAIKDYELQ 1425 Query: 165 KLMLQKELEMIREENRKLDDQNHSSTSVIIRLQD------EIISLKNAQRKLEEEVSRHV 326 + + +LE + +K Q+ S SVI D E+ +L + K E R + Sbjct: 1426 LITYKAQLEPVASPAKKPKVQS-GSESVIQEYVDLRTRYSELTTLTSQYIKFISETLRRM 1484 Query: 327 EEKKALQHE 353 EE++ L + Sbjct: 1485 EEEERLAEQ 1493
>YAF3_SCHPO (Q09857) Hypothetical protein C29E6.03c in chromosome I| Length = 1044 Score = 36.2 bits (82), Expect = 0.035 Identities = 41/152 (26%), Positives = 69/152 (45%), Gaps = 13/152 (8%) Frame = +3 Query: 15 SIQEEQL-KSMQAEMARLSLEKQLAQV--------QEKLRLLSLEKHGETSKCKDVEASK 167 SIQEE+L +S++ L + QLA+ Q+KL L +E S CK +E Sbjct: 630 SIQEEKLNESLKTSKTNLEEQTQLAEKYHEELLDNQQKLYDLRIELDYTKSNCKQMEEEM 689 Query: 168 LML----QKELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEK 335 +L + E++ EE+ KL Q I+ Q IIS KN ++ +E+ Sbjct: 690 QVLREGHESEIKDFIEEHSKLTKQLDD-----IKNQFGIISSKN------RDLLSELEKS 738 Query: 336 KALQHELSHIXNDRGDVERKHFSIKEQIQAVN 431 K+L + L+ + + +E + E++ N Sbjct: 739 KSLNNSLAALESKNKKLENDLNLLTEKLNKKN 770 Score = 34.3 bits (77), Expect = 0.13 Identities = 31/141 (21%), Positives = 61/141 (43%), Gaps = 7/141 (4%) Frame = +3 Query: 21 QEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIR 200 Q+ QLKS++ E + K+ + K R + EK E+ K SK L+++ ++ Sbjct: 604 QKMQLKSLREE---IDNTKEALDLSVKERSIQEEKLNESLK-----TSKTNLEEQTQLAE 655 Query: 201 EENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKL-------EEEVSRHVEEKKALQHELS 359 + + +L D + I L + K + ++ E E+ +EE L +L Sbjct: 656 KYHEELLDNQQKLYDLRIELDYTKSNCKQMEEEMQVLREGHESEIKDFIEEHSKLTKQLD 715 Query: 360 HIXNDRGDVERKHFSIKEQIQ 422 I N G + K+ + +++ Sbjct: 716 DIKNQFGIISSKNRDLLSELE 736
>M4K4_HUMAN (O95819) Mitogen-activated protein kinase kinase kinase kinase 4| (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase) Length = 1239 Score = 36.2 bits (82), Expect = 0.035 Identities = 32/132 (24%), Positives = 60/132 (45%) Frame = +3 Query: 21 QEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIR 200 QE + +S +L E+QL + +E R L E+ + K+ + L+++ R Sbjct: 361 QENKERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKE---QRRRLEEQQRRER 417 Query: 201 EENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHIXNDRG 380 E R+ + + R +E+ +RK EEE R EEK+ ++ E +I Sbjct: 418 EARRQQEREQRRREQEEKRRLEEL----ERRRKEEEERRRAEEEKRRVEREQEYIRRQL- 472 Query: 381 DVERKHFSIKEQ 416 + E++H + +Q Sbjct: 473 EEEQRHLEVLQQ 484
>LUZP1_HUMAN (Q86V48) Leucine zipper protein 1| Length = 1076 Score = 36.2 bits (82), Expect = 0.035 Identities = 39/153 (25%), Positives = 72/153 (47%), Gaps = 22/153 (14%) Frame = +3 Query: 30 QLKSMQAEMARLS-LEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIREE 206 ++K +++ RL E+ LA EKL+ L+L E + E L KEL E+ Sbjct: 161 KVKELESSEDRLDKTEQSLASELEKLKSLTLSFVSERKYLNEKEKENEKLIKELTQKLEQ 220 Query: 207 NRKLDDQNHSSTSVI----IRLQDEIISL---KNAQRK--------LEEEVSRHVEEKKA 341 N+K++ + S + +R++D I S K ++RK +E E E +K Sbjct: 221 NKKMNRDYTRNASNLERNDLRIEDGISSTLPSKESRRKGGLDYLKQVENETRNKSENEKN 280 Query: 342 LQHELSHIXNDRGDVER-----KHF-SIKEQIQ 422 E + + + ++E+ KHF S++E+++ Sbjct: 281 RNQEDNKVKDLNQEIEKLKTQIKHFESLEEELK 313 Score = 29.6 bits (65), Expect = 3.3 Identities = 24/147 (16%), Positives = 64/147 (43%), Gaps = 9/147 (6%) Frame = +3 Query: 21 QEEQLKSMQAEMARLSLE-KQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMI 197 ++ ++K + E+ +L + K ++E+L+ + + + + +L +LE I Sbjct: 284 EDNKVKDLNQEIEKLKTQIKHFESLEEELKKMKSKNNDLQDNYLSEQNKNKLLASQLEEI 343 Query: 198 REENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKL-------EEEVSRHVEEKKALQHEL 356 + + +K + + + +D +S K + E VS+H + + QH+ Sbjct: 344 KLQIKKQKELENGE----VEGEDAFLSSKGRHERTKFRGHGSEASVSKHTARELSPQHKR 399 Query: 357 SHIXNDRGDVERKHFSI-KEQIQAVNF 434 + N + +++S+ Q+ + +F Sbjct: 400 ERLRNREFALNNENYSLSNRQVSSPSF 426
>PEPL_HUMAN (O60437) Periplakin (195 kDa cornified envelope precursor protein)| (190 kDa paraneoplastic pemphigus antigen) Length = 1756 Score = 36.2 bits (82), Expect = 0.035 Identities = 32/136 (23%), Positives = 68/136 (50%), Gaps = 1/136 (0%) Frame = +3 Query: 21 QEEQLKSMQAEMARLSLEKQLAQVQEKLR-LLSLEKHGETSKCKDVEASKLMLQKELEMI 197 QEE+L +Q ++ RL E+ +A+ + ++ +L +EK T + E S L Q E Sbjct: 1087 QEEELSFLQDKLKRLEKERAMAEGKITVKEVLKVEKDAATER----EVSDLTRQYE---- 1138 Query: 198 REENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHIXNDR 377 +E K T ++ ++ + +NA+ ++E+V V + E++++ + Sbjct: 1139 -DEAAKARASQREKTELLRKIW--ALEEENAKVVVQEKVREIVRPDPKAESEVANLRLEL 1195 Query: 378 GDVERKHFSIKEQIQA 425 + ERK+ +EQ+++ Sbjct: 1196 VEQERKYRGAEEQLRS 1211 Score = 35.0 bits (79), Expect = 0.079 Identities = 41/144 (28%), Positives = 69/144 (47%), Gaps = 12/144 (8%) Frame = +3 Query: 24 EEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCK-DVEASKLMLQKELEMIR 200 EEQL+S Q+E+ L +V+E + E K K D E ++KEL+ +R Sbjct: 1206 EEQLRSYQSELEALRRRGPQVEVKEVTK--------EVIKYKTDPE-----MEKELQRLR 1252 Query: 201 EENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLE-EEVSRHV----------EEKKALQ 347 EE I +L+ EI +LK+ + +++ +EV + + EE +L+ Sbjct: 1253 EEIVDKTRLIERCDLEIYQLKKEIQALKDTKPQVQTKEVVQEILQFQEDPQTKEEVASLR 1312 Query: 348 HELSHIXNDRGDVERKHFSIKEQI 419 +LS + D+ER+ S +EQI Sbjct: 1313 AKLSEEQKKQVDLERERASQEEQI 1336 Score = 34.7 bits (78), Expect = 0.10 Identities = 36/146 (24%), Positives = 64/146 (43%), Gaps = 5/146 (3%) Frame = +3 Query: 6 LSVSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKE 185 LS S+Q E+ + Q E+ RL + L + R L +E ++ ++E KE Sbjct: 1501 LSESVQVEKGDTEQ-EIQRL--KSSLEEESRSKRELDVEVSRLEARLSELEFHNSKSSKE 1557 Query: 186 LEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLE-----EEVSRHVEEKKALQH 350 L+ +REEN KL + + RLQ EI R L + + H +L+ Sbjct: 1558 LDFLREENHKLQLERQNLQLETRRLQSEINMAATETRDLRNMTVADSGTNHDSRLWSLER 1617 Query: 351 ELSHIXNDRGDVERKHFSIKEQIQAV 428 EL + D + + +++++ +V Sbjct: 1618 ELDDLKRLSKDKDLEIDELQKRLGSV 1643
>MYO2_SCHPO (Q9USI6) Myosin type-2 heavy chain 1 (Myosin type II heavy chain 1)| Length = 1526 Score = 36.2 bits (82), Expect = 0.035 Identities = 40/160 (25%), Positives = 68/160 (42%), Gaps = 19/160 (11%) Frame = +3 Query: 6 LSVSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKE 185 + + QE K SL +Q A +EKL L S E ++K + L + Sbjct: 1187 VDTNFQELSKKHRDLTFNHESLLRQSASYKEKLSLASSENKDLSNKVSSLTKQVNELSPK 1246 Query: 186 LEMIREENRKLDDQNHSSTS-------------VIIRLQDEIISLKN---AQRKLEEEVS 317 + E RK+ + H + + R +E+ SLK+ ++RKLE E Sbjct: 1247 ASKVPELERKITNLMHEYSQLGKTFEDEKRKALIASRDNEELRSLKSELESKRKLEVEYQ 1306 Query: 318 RHVEEKK---ALQHELSHIXNDRGDVERKHFSIKEQIQAV 428 + +EE K +L+ E++ + N D H SI+ ++ V Sbjct: 1307 KVLEEVKTTRSLRSEVTLLRNKVAD----HESIRSKLSEV 1342 Score = 31.6 bits (70), Expect = 0.87 Identities = 29/113 (25%), Positives = 49/113 (43%), Gaps = 5/113 (4%) Frame = +3 Query: 9 SVSIQEEQLKSMQAEMARLS-----LEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLM 173 S S ++Q +++Q E A L LE +L + K+ L E++ K E L Sbjct: 895 SFSETKQQNENLQRESASLKQINNELESELLEKTSKVETLLSEQNELKEKLSLEEKDLLD 954 Query: 174 LQKELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEE 332 + ELE +RE N + + LQ+ I++ KL + +S + E Sbjct: 955 TKGELESLRENNATVLSEKAEFNEQCKSLQETIVTKDAELDKLTKYISDYKTE 1007
>MYH6_MOUSE (Q02566) Myosin heavy chain, cardiac muscle alpha isoform| (MyHC-alpha) Length = 1938 Score = 36.2 bits (82), Expect = 0.035 Identities = 34/132 (25%), Positives = 56/132 (42%), Gaps = 7/132 (5%) Frame = +3 Query: 24 EEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELE---- 191 E LK Q + + LE Q++EKL+ + + SK +D +A L LQK+L+ Sbjct: 1058 EGDLKLTQESI--MDLENDKLQLEEKLKKKEFDISQQNSKIEDEQALALQLQKKLKENQA 1115 Query: 192 MIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEE---EVSRHVEEKKALQHELSH 362 I E +L+ + + V D L+ +LEE S +E K + E Sbjct: 1116 RIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQK 1175 Query: 363 IXNDRGDVERKH 398 + D + +H Sbjct: 1176 MRRDLEEATLQH 1187 Score = 33.9 bits (76), Expect = 0.18 Identities = 31/149 (20%), Positives = 65/149 (43%), Gaps = 22/149 (14%) Frame = +3 Query: 6 LSVSIQEEQLKSMQAEMARLSLEKQLAQVQEKL-RLLSLEKHGETSKCKDVEASKLMLQK 182 ++ +++EQ S E + ++E+ + +Q +L + G + + +EA L+ Sbjct: 1767 MAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEN 1826 Query: 183 ELEMIREEN--------------RKLDDQNHSSTSVIIRLQDEIISL-------KNAQRK 299 ELE ++ N ++L Q ++RLQD + L K + Sbjct: 1827 ELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKKNLMRLQDLVDKLQLKVKAYKRQAEE 1886 Query: 300 LEEEVSRHVEEKKALQHELSHIXNDRGDV 386 EE+ + ++ + + +QHEL +R D+ Sbjct: 1887 AEEQANTNLSKFRKVQHELDE-AEERADI 1914 Score = 33.1 bits (74), Expect = 0.30 Identities = 31/144 (21%), Positives = 56/144 (38%), Gaps = 28/144 (19%) Frame = +3 Query: 36 KSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELE-------- 191 ++ + E A+ L ++L +E + ++ +KC +E +K LQ E+E Sbjct: 1384 RTEELEEAKKKLAQRLQDAEEAVEAVN-------AKCSSLEKTKHRLQNEIEDLMVDVER 1436 Query: 192 -----------------MIREENRKLDDQN---HSSTSVIIRLQDEIISLKNAQRKLEEE 311 ++ E +K ++ SS L E+ LKNA + E Sbjct: 1437 SNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEH 1496 Query: 312 VSRHVEEKKALQHELSHIXNDRGD 383 + E K LQ E+S + G+ Sbjct: 1497 LETFKRENKNLQEEISDLTEQLGE 1520 Score = 32.0 bits (71), Expect = 0.67 Identities = 27/136 (19%), Positives = 63/136 (46%) Frame = +3 Query: 24 EEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIRE 203 E + K ++ +M L EK Q+Q + +L E +C + +K+ L+ + ++E Sbjct: 869 EARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAEE--RCDQLIKNKIQLEAK---VKE 923 Query: 204 ENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHIXNDRGD 383 +L+D+ + + + +RKLE+E S ++ L+ L+ + ++ Sbjct: 924 MTERLEDEEEMNAELTAK-----------KRKLEDECSELKKDIDDLELTLAKVEKEKHA 972 Query: 384 VERKHFSIKEQIQAVN 431 E K ++ E++ ++ Sbjct: 973 TENKVKNLTEEMAGLD 988 Score = 29.3 bits (64), Expect = 4.3 Identities = 28/126 (22%), Positives = 62/126 (49%), Gaps = 16/126 (12%) Frame = +3 Query: 27 EQLKSMQAEMARLSLEKQLAQV------------QEKLRLLSLEKHGETSKCKDVEASKL 170 E++ + +A+L+ EK+ Q ++K+ L+ K + D+E S L Sbjct: 982 EEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKSKVKLEQQVDDLEGS-L 1040 Query: 171 MLQKELEM-IREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRH---VEEKK 338 +K++ M + RKL+ + I+ L+++ + L+ +K E ++S+ +E+++ Sbjct: 1041 EQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDISQQNSKIEDEQ 1100 Query: 339 ALQHEL 356 AL +L Sbjct: 1101 ALALQL 1106
>IF2_CAMJR (Q5HX30) Translation initiation factor IF-2| Length = 871 Score = 35.8 bits (81), Expect = 0.046 Identities = 35/156 (22%), Positives = 70/156 (44%), Gaps = 19/156 (12%) Frame = +3 Query: 21 QEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLML---QKELE 191 +EE+LK + + L +EK+ A+ +EK ++ K + + L++ +K+ E Sbjct: 92 KEEKLKQ-EVKKEELKIEKENAKEEEKQEIIDAHKPQSLASATLAKRRGLVIVKKKKDEE 150 Query: 192 MIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKAL--------- 344 I+ + ++ + N S + +E +SLK +E + + +EKK+ Sbjct: 151 EIQVKKEEVKNSNDISIN-----NEERLSLKTMFSNADESLKKKKKEKKSFVASKKESTE 205 Query: 345 ------QHELSHIX-NDRGDVERKHFSIKEQIQAVN 431 +H+ I +D +V FS+KEQ + N Sbjct: 206 KMNFLDEHDFGDISLDDEDEVVLPDFSVKEQEKPQN 241
>IF2_CAMJE (Q9PIZ1) Translation initiation factor IF-2| Length = 871 Score = 35.8 bits (81), Expect = 0.046 Identities = 35/156 (22%), Positives = 70/156 (44%), Gaps = 19/156 (12%) Frame = +3 Query: 21 QEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLML---QKELE 191 +EE+LK + + L +EK+ A+ +EK ++ K + + L++ +K+ E Sbjct: 92 KEEKLKQ-EVKKEELKIEKENAKEEEKQEIIDAHKPQSLASATLAKRRGLVIVKKKKDEE 150 Query: 192 MIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKAL--------- 344 I+ + ++ + N S + +E +SLK +E + + +EKK+ Sbjct: 151 EIQVKKEEVKNSNDISIN-----NEERLSLKTMFSNADESLKKKKKEKKSFVASKKESTE 205 Query: 345 ------QHELSHIX-NDRGDVERKHFSIKEQIQAVN 431 +H+ I +D +V FS+KEQ + N Sbjct: 206 KMNFLDEHDFGDISLDDEDEVVLPDFSVKEQEKPQN 241
>MYSC_CHICK (P29616) Myosin heavy chain, cardiac muscle isoform (Fragment)| Length = 1102 Score = 35.8 bits (81), Expect = 0.046 Identities = 37/152 (24%), Positives = 75/152 (49%), Gaps = 9/152 (5%) Frame = +3 Query: 3 KLSVSIQEEQLKSMQA----EMARLSLE-KQLAQVQEKLRLLSLEKHGETSKCKDVEAS- 164 K +++EE LK +A E R LE KQ++ VQEK LL L+ E D E Sbjct: 13 KEMANMKEEFLKLKEALEKSEARRKELEEKQVSLVQEKNDLL-LQLQAEQDTLADAEERC 71 Query: 165 KLMLQKELEM---IREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEK 335 L+++ ++++ ++E +++D+ ++ L + +RKLE+E S ++ Sbjct: 72 DLLIKSKIQLEAKVKELTERVEDEEEMNSE-----------LTSKKRKLEDECSELKKDI 120 Query: 336 KALQHELSHIXNDRGDVERKHFSIKEQIQAVN 431 L+ L+ + ++ E K ++ E++ ++ Sbjct: 121 DDLEITLAKVEKEKHATENKVKNLTEEMATLD 152 Score = 33.9 bits (76), Expect = 0.18 Identities = 25/116 (21%), Positives = 51/116 (43%) Frame = +3 Query: 24 EEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIRE 203 EE +++ A+ + L K Q +++ ++ LEK S ++ + K + ++ Sbjct: 567 EEAIEAANAKCSSLEKAKHRLQNEQEDMMIDLEK--ANSAAASLDKKQRGFDKIINDWKQ 624 Query: 204 ENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHIXN 371 + + + +S L E+ LKNA + + + E K LQ E+S + N Sbjct: 625 KYEESQAELEASQKEARSLSTELFKLKNAYEETLDHLETLKRENKNLQEEISDLTN 680 Score = 33.9 bits (76), Expect = 0.18 Identities = 22/97 (22%), Positives = 47/97 (48%) Frame = +3 Query: 24 EEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIRE 203 E LK Q + + LE Q++EKL+ E SK +D +A + LQK+++ ++ Sbjct: 222 EGDLKLTQESV--MDLENDKLQMEEKLKKKEFEMSQLNSKIEDEQAIVMQLQKKIKELQA 279 Query: 204 ENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEV 314 +L+++ + + +++ + L +L E + Sbjct: 280 RIEELEEELEAERAARAKVEKQRSDLARELEELSERL 316 Score = 33.1 bits (74), Expect = 0.30 Identities = 30/142 (21%), Positives = 65/142 (45%), Gaps = 3/142 (2%) Frame = +3 Query: 6 LSVSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKE 185 L S+++E+ M E A+ LE L QE + D+E KL ++++ Sbjct: 200 LEGSLEQEKKVRMDLERAKRKLEGDLKLTQESVM--------------DLENDKLQMEEK 245 Query: 186 LEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHE---L 356 L+ E +L+ + +++++LQ +K++E +R E ++ L+ E Sbjct: 246 LKKKEFEMSQLNSKIEDEQAIVMQLQ----------KKIKELQARIEELEEELEAERAAR 295 Query: 357 SHIXNDRGDVERKHFSIKEQIQ 422 + + R D+ R+ + E+++ Sbjct: 296 AKVEKQRSDLARELEELSERLE 317 Score = 29.3 bits (64), Expect = 4.3 Identities = 31/130 (23%), Positives = 57/130 (43%), Gaps = 11/130 (8%) Frame = +3 Query: 72 EKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIREENRKLDDQNHSSTSVI 251 + +L Q++ R LS E K K+ L LE ++ EN+ L ++ T+ I Sbjct: 630 QAELEASQKEARSLSTELF----KLKNAYEETL---DHLETLKRENKNLQEEISDLTNQI 682 Query: 252 IRLQDEIISLKNAQRKLEEEVSR----HVEEKKALQHELS-------HIXNDRGDVERKH 398 + ++ ++++E+E S E + AL+HE S + + D ERK Sbjct: 683 SEGNKNLHEIEKVKKQVEQEKSEVQLALEEAEGALEHEESKTLRFQLELSQLKADFERKL 742 Query: 399 FSIKEQIQAV 428 E++Q + Sbjct: 743 AEKDEEMQNI 752 Score = 28.1 bits (61), Expect = 9.7 Identities = 32/139 (23%), Positives = 58/139 (41%) Frame = +3 Query: 12 VSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELE 191 ++ Q+ +L+S E R Q++EK L+S G+TS + +E Sbjct: 439 LTTQKTKLQSENGEFVR--------QLEEKESLISQLSRGKTSFTQQIE----------- 479 Query: 192 MIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHIXN 371 E R+L+++ S ++ LQ + ++ L E+ E K LQ LS Sbjct: 480 ---ELRRQLEEETKSKNALAHALQ----AARHDCDLLREQYEEEQEAKAELQRALS---- 528 Query: 372 DRGDVERKHFSIKEQIQAV 428 +G+ E + K + A+ Sbjct: 529 -KGNAEVAQWRTKYETDAI 546 Score = 28.1 bits (61), Expect = 9.7 Identities = 26/126 (20%), Positives = 63/126 (50%), Gaps = 16/126 (12%) Frame = +3 Query: 27 EQLKSMQAEMARLSLEKQLAQV------------QEKLRLLSLEKHGETSKCKDVEASKL 170 E++ ++ +++L+ EK+ Q ++K+ LS K + D+E S L Sbjct: 146 EEMATLDENISKLTKEKKSLQEAHQQVLDDLQAEEDKVNTLSKAKVKLEQQVDDLEGS-L 204 Query: 171 MLQKELEM-IREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSR---HVEEKK 338 +K++ M + RKL+ + ++ L+++ + ++ +K E E+S+ +E+++ Sbjct: 205 EQEKKVRMDLERAKRKLEGDLKLTQESVMDLENDKLQMEEKLKKKEFEMSQLNSKIEDEQ 264 Query: 339 ALQHEL 356 A+ +L Sbjct: 265 AIVMQL 270
>MYH6_RABIT (P04460) Myosin heavy chain, cardiac muscle alpha isoform| (MyHC-alpha) (Alpha isomyosin) (Fragment) Length = 465 Score = 35.8 bits (81), Expect = 0.046 Identities = 30/143 (20%), Positives = 67/143 (46%) Frame = +3 Query: 3 KLSVSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQK 182 K S+ E + K ++ +M L EK Q+Q + +L E +C + +K+ L+ Sbjct: 57 KESLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAEE--RCDQLIKNKIQLEA 114 Query: 183 ELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSH 362 + ++E N +L+D+ + + + +RKLE+E S ++ L+ L+ Sbjct: 115 K---VKEMNERLEDEEEMNAELTAK-----------KRKLEDECSELKKDIDDLELTLAK 160 Query: 363 IXNDRGDVERKHFSIKEQIQAVN 431 + ++ E K ++ E++ ++ Sbjct: 161 VEKEKHATENKVKNLTEEMAGLD 183 Score = 33.5 bits (75), Expect = 0.23 Identities = 37/149 (24%), Positives = 71/149 (47%), Gaps = 11/149 (7%) Frame = +3 Query: 18 IQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMI 197 +Q E+ K A+L LE+Q+ ++ SLE+ E D+E +K L+ +L++ Sbjct: 207 LQAEEDKVNTLTKAKLKLEQQVDDLEG-----SLEQ--EKKVRMDLERAKRKLEGDLKLT 259 Query: 198 RE-----ENRK------LDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKAL 344 +E EN K L + + + +++DE + Q+KL+E +R +EE L Sbjct: 260 QESIMDLENDKQQLEERLKKKEFDISQLNSKIEDEQALVLQLQKKLKENQAR-IEE---L 315 Query: 345 QHELSHIXNDRGDVERKHFSIKEQIQAVN 431 + EL R VE+ + +++ ++ Sbjct: 316 EEELEAERTARAKVEKLRSDLSRELEEIS 344
>MY18A_HUMAN (Q92614) Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain)| (Molecule associated with JAK3 N-terminus) (MAJN) Length = 2054 Score = 35.8 bits (81), Expect = 0.046 Identities = 31/142 (21%), Positives = 68/142 (47%), Gaps = 3/142 (2%) Frame = +3 Query: 6 LSVSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKE 185 L +Q+ + + E + ++KQL ++ K++ E + + +E +KL L+ E Sbjct: 1519 LEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEME 1578 Query: 186 LEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEV---SRHVEEKKALQHEL 356 +E +R+ + K + V Q LK + +LEEE + + EK+ L+ +L Sbjct: 1579 MERMRQTHSK--EMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKL 1636 Query: 357 SHIXNDRGDVERKHFSIKEQIQ 422 + + + V R+ F +++++ Sbjct: 1637 ATLSD---QVNRRDFESEKRLR 1655 Score = 33.5 bits (75), Expect = 0.23 Identities = 33/155 (21%), Positives = 67/155 (43%), Gaps = 23/155 (14%) Frame = +3 Query: 3 KLSVSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQK 182 ++ V ++EE + + LE +LA + +++ E E KD++ +K +L Sbjct: 1610 QMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNRRDFES--EKRLRKDLKRTKALLAD 1667 Query: 183 ELEMI---------REENRKLDDQNHSST-----------SVIIRLQD---EIISLKNAQ 293 M+ + E +L +Q S ++ + ++D +I + A+ Sbjct: 1668 AQLMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAK 1727 Query: 294 RKLEEEVSRHVEEKKALQHELSHIXNDRGDVERKH 398 LEE++SR EK +Q+ L D ++ +KH Sbjct: 1728 TALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKH 1762 Score = 31.6 bits (70), Expect = 0.87 Identities = 23/118 (19%), Positives = 59/118 (50%), Gaps = 1/118 (0%) Frame = +3 Query: 72 EKQLAQ-VQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIREENRKLDDQNHSSTSV 248 +K+L Q ++KL + K + D++A Q+ L+ ++++ ++L + + Sbjct: 1386 KKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLH 1445 Query: 249 IIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHIXNDRGDVERKHFSIKEQIQ 422 + Q L+ QR+ + E+S+ EE + + + + ++ + + FS+K+Q++ Sbjct: 1446 LEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLE 1503
>SUDA_EMENI (Q00737) Chromosome segregation protein sudA (DA-box protein sudA)| Length = 1211 Score = 35.8 bits (81), Expect = 0.046 Identities = 23/136 (16%), Positives = 62/136 (45%) Frame = +3 Query: 6 LSVSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKE 185 L +I + + + + + L ++Q + + EK + V+A +++ Sbjct: 223 LEYTIYSREQQEIASFLDSLEEQRQTGVEDTDINFIQGEK-----EMAQVDAEIAECKQQ 277 Query: 186 LEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHI 365 +E ++ + +L+D+ ++ + +++ + SL + Q +E +RH E KA+Q + Sbjct: 278 IEFLKVDKAQLEDERREASKALAQVELQAKSLSDNQAAAQESKARHDESLKAVQSAIEER 337 Query: 366 XNDRGDVERKHFSIKE 413 + ++ + S K+ Sbjct: 338 QTELKELVPRFISAKD 353
>MYSA_DROME (P05661) Myosin heavy chain, muscle| Length = 1962 Score = 35.8 bits (81), Expect = 0.046 Identities = 36/143 (25%), Positives = 68/143 (47%), Gaps = 10/143 (6%) Frame = +3 Query: 24 EEQLKSMQAEMARLS----LEKQLAQVQEKLR------LLSLEKHGETSKCKDVEASKLM 173 EE+ K + ARL+ E+ AQ QEKLR + L+ + ++ ++ K Sbjct: 1751 EEKAKKAMVDAARLADELRAEQDHAQTQEKLRKALEQQIKELQVRLDEAEANALKGGKKA 1810 Query: 174 LQKELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHE 353 +QK + +RE +LD + R D +L+ ++R+++E + E++K HE Sbjct: 1811 IQKLEQRVRELENELDGEQR-------RHADAQKNLRKSERRVKELSFQSEEDRK--NHE 1861 Query: 354 LSHIXNDRGDVERKHFSIKEQIQ 422 D+ +++K + K QI+ Sbjct: 1862 RMQDLVDK--LQQKIKTYKRQIE 1882 Score = 34.3 bits (77), Expect = 0.13 Identities = 29/114 (25%), Positives = 57/114 (50%), Gaps = 7/114 (6%) Frame = +3 Query: 69 LEKQLAQVQEKLRLLSLEKHGETSKCKDVEA--SKLMLQKE--LEMIREENRKLDDQNHS 236 +E ++A+++EK + E K++EA +KL+ +K L+ + E L D Sbjct: 844 IEDEIARLEEKAKKAEELHAAEVKVRKELEALNAKLLAEKTALLDSLSGEKGALQDYQER 903 Query: 237 STSVIIRLQDEIISLKNAQRKL-EEEVSRH--VEEKKALQHELSHIXNDRGDVE 389 + + + D L++ Q +L +EE +R+ ++KK E+S + D D+E Sbjct: 904 NAKLTAQKNDLENQLRDIQERLTQEEDARNQLFQQKKKADQEISGLKKDIEDLE 957
>UACA_HUMAN (Q9BZF9) Uveal autoantigen with coiled-coil domains and ankyrin| repeats protein Length = 1416 Score = 35.8 bits (81), Expect = 0.046 Identities = 27/155 (17%), Positives = 74/155 (47%), Gaps = 12/155 (7%) Frame = +3 Query: 3 KLSVSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQK 182 +L+ + E + +++ E + ++Q+ Q+++ L+ + + K K ++ L L++ Sbjct: 466 ELAHKVAECKALALECERVKEDSDEQIKQLEDALKDVQKRMYESEGKVKQMQTHFLALKE 525 Query: 183 EL------------EMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHV 326 L E ++++ + L + +++ + +L+++I + + + + + + Sbjct: 526 HLTSEAASGNHRLTEELKDQLKDLKVKYEGASAEVGKLRNQIKQNEMIVEEFKRDEGKLI 585 Query: 327 EEKKALQHELSHIXNDRGDVERKHFSIKEQIQAVN 431 EE K LQ ELS +R RK ++ Q + ++ Sbjct: 586 EENKRLQKELSMCEMEREKKGRKVTEMEGQAKELS 620 Score = 35.4 bits (80), Expect = 0.061 Identities = 32/138 (23%), Positives = 66/138 (47%), Gaps = 15/138 (10%) Frame = +3 Query: 24 EEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSK-CKDVEASKLMLQKELEMIR 200 + +L++++A++A+ ++ QV+ +L +K GE K ++ LQKE+E + Sbjct: 668 KRELENVKAKLAQHVKPEEHEQVKSRLE----QKSGELGKKITELTLKNQTLQKEIEKVY 723 Query: 201 EENRKLDDQNHSSTSVIIRLQDEIISLK--------------NAQRKLEEEVSRHVEEKK 338 +N+ L +Q H+ T I +++ + LK + RKL + ++ E+K Sbjct: 724 LDNKLLKEQAHNLT---IEMKNHYVPLKVSEDMKKSHDAIIDDLNRKLLDVTQKYTEKKL 780 Query: 339 ALQHELSHIXNDRGDVER 392 ++ L + DV R Sbjct: 781 EMEKLLLENDSLSKDVSR 798
>INT1_CANAL (P53705) Integrin alpha chain-like protein (Alpha-INT1)| Length = 1664 Score = 35.8 bits (81), Expect = 0.046 Identities = 39/134 (29%), Positives = 59/134 (44%), Gaps = 8/134 (5%) Frame = +3 Query: 45 QAEMARLSLEKQLAQVQEKLRLLSLEKHGETS-----KCKDVEASKLMLQK---ELEMIR 200 Q++++ +LEKQ Q QE+ + + E ETS K K S L K + E + Sbjct: 461 QSQISLNALEKQ-RQTQEQEQTQAAEPEEETSFSDNIKVKQEPKSNLEFVKVTIKKEPVS 519 Query: 201 EENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHIXNDRG 380 K + SS + I+ +DEI + K E E + HVE+ AL L ND Sbjct: 520 ATEIKAPKREFSSRILRIKNEDEIAEPADIHPKKENEANSHVEDTDAL---LKKALNDDE 576 Query: 381 DVERKHFSIKEQIQ 422 + + S K I+ Sbjct: 577 ESDTTQNSTKMSIR 590
>SDCG8_MOUSE (Q80UF4) Serologically defined colon cancer antigen 8 (Centrosomal| colon cancer autoantigen protein) (mCCCAP) Length = 717 Score = 35.8 bits (81), Expect = 0.046 Identities = 31/161 (19%), Positives = 75/161 (46%), Gaps = 23/161 (14%) Frame = +3 Query: 18 IQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHG-ETSKCKDVEASKLMLQKELEM 194 +++EQ K+ +A L + + L + + +L L LEK + S + +A L Q+ + Sbjct: 511 VEQEQQKAARARQECLRVTELLGEAERQLHLTRLEKDSIQQSFSNEAKAQALQAQQREQE 570 Query: 195 IREENRKLDDQNH-----------SSTSVIIRLQDEII----SLKNAQRKLEEEVSRHVE 329 + ++ ++++ Q+ S + + +L++E L+ K ++ R + Sbjct: 571 LTQKIQQMETQHDKTESEQYLLLTSQNTFLTKLKEECCLLAKKLEKVSLKSRSQIVRLSQ 630 Query: 330 EKKALQHELSHIXNDRGDVE-------RKHFSIKEQIQAVN 431 EK+ L +L + ++E R H ++KE+++ ++ Sbjct: 631 EKRYLCDKLEKLQKRNDELEEQCIQHGRVHETMKERLRQLD 671
>MYSP_ONCVO (Q02171) Paramyosin| Length = 879 Score = 35.8 bits (81), Expect = 0.046 Identities = 29/124 (23%), Positives = 54/124 (43%) Frame = +3 Query: 24 EEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIRE 203 EEQ++ M ++++L K Q + ++ ++ LEK T +E +K L+K + ++ Sbjct: 333 EEQIEIMLQKISQLEKAKSRLQSEVEVLIVDLEKAQNTIAI--LERAKEQLEKTVNELKV 390 Query: 204 ENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHIXNDRGD 383 +L + ++ E+ +KN K E+ E K LQ +L D Sbjct: 391 RIDELTVELEAAQREARAALAELQKMKNLYEKAVEQKEALARENKKLQDDLHEAKEALAD 450 Query: 384 VERK 395 RK Sbjct: 451 ANRK 454 Score = 33.5 bits (75), Expect = 0.23 Identities = 26/100 (26%), Positives = 49/100 (49%), Gaps = 2/100 (2%) Frame = +3 Query: 18 IQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMI 197 + EEQ SM+ + R SLE+Q+ Q+Q ++ + ++ + K ++ K I Sbjct: 702 LHEEQEHSMKIDALRKSLEEQVKQLQVQI---------QEAEAAALLGGKRVIAKLETRI 752 Query: 198 REENRKLDDQ--NHSSTSVIIRLQDEIISLKNAQRKLEEE 311 R+ LD++ H T +R +D +K Q +++EE Sbjct: 753 RDLETALDEETRRHKETQGALRKKDR--RIKEVQMQVDEE 790 Score = 32.7 bits (73), Expect = 0.39 Identities = 35/126 (27%), Positives = 60/126 (47%), Gaps = 7/126 (5%) Frame = +3 Query: 66 SLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASK-----LMLQKELEMIREENRKLDDQN 230 S K+ A++Q KLR L E E +V K L +++E ++++N K+D + Sbjct: 95 SNRKREAELQ-KLRKLLEESQLENEDAMNVLRKKHQDACLDYTEQIEQLQKKNSKIDRER 153 Query: 231 HSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELS--HIXNDRGDVERKHFS 404 RLQ E+I L A +L+++ +H+ EK A + E + N D+ R Sbjct: 154 Q-------RLQHEVIELTAAIDQLQKD--KHLAEKAAERFEAQTIELSNKVEDLNRHVND 204 Query: 405 IKEQIQ 422 + +Q Q Sbjct: 205 LAQQRQ 210 Score = 30.4 bits (67), Expect = 1.9 Identities = 33/130 (25%), Positives = 60/130 (46%), Gaps = 12/130 (9%) Frame = +3 Query: 21 QEEQLKSMQAEMARLS--LEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEM 194 Q E + +AE+ +L LE+ + ++ + +L +KH + C D LQK+ Sbjct: 92 QIESNRKREAELQKLRKLLEESQLENEDAMNVLR-KKHQDA--CLDYTEQIEQLQKKNSK 148 Query: 195 IREENRKLDDQNHSSTSVIIRLQ-DEIISLKNAQR---------KLEEEVSRHVEEKKAL 344 I E ++L + T+ I +LQ D+ ++ K A+R E+++RHV + Sbjct: 149 IDRERQRLQHEVIELTAAIDQLQKDKHLAEKAAERFEAQTIELSNKVEDLNRHVNDLAQQ 208 Query: 345 QHELSHIXND 374 + L ND Sbjct: 209 RQRLQAENND 218 Score = 28.9 bits (63), Expect = 5.7 Identities = 21/92 (22%), Positives = 43/92 (46%) Frame = +3 Query: 69 LEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIREENRKLDDQNHSSTSV 248 L +Q ++Q + L E H + + +++ K L ++LE E R+L+D + + Sbjct: 205 LAQQRQRLQAENNDLLKEIHDQKVQLDNLQHVKYQLAQQLE---EARRRLEDAERERSQL 261 Query: 249 IIRLQDEIISLKNAQRKLEEEVSRHVEEKKAL 344 +L + L + + L+EE + E + L Sbjct: 262 QAQLHQVQLELDSVRTALDEESAARAEAEHKL 293
>BICD_DROME (P16568) Cytoskeleton-like bicaudal D protein| Length = 782 Score = 35.8 bits (81), Expect = 0.046 Identities = 31/127 (24%), Positives = 62/127 (48%), Gaps = 13/127 (10%) Frame = +3 Query: 90 VQEKLRLLSLEKHGETS---KCKDVEASKLMLQKELEMIREENRKLDDQN-------HSS 239 ++++ LL+ ETS + D+E L+ ELE +R E ++ +N S Sbjct: 93 IEQEDALLNESAARETSLNLQIFDLENELKQLRHELERVRNERDRMLQENSDFGRDKSDS 152 Query: 240 TSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHIXNDRGDVERKHFSIK--- 410 + +RL+ E+ LK + ++ E S EE +LQ ++S + + + + E I+ Sbjct: 153 EADRLRLKSELKDLKFRETRMLSEYSELEEENISLQKQVSSLRSSQVEFEGAKHEIRRLT 212 Query: 411 EQIQAVN 431 E+++ +N Sbjct: 213 EEVELLN 219 Score = 35.8 bits (81), Expect = 0.046 Identities = 31/124 (25%), Positives = 56/124 (45%), Gaps = 6/124 (4%) Frame = +3 Query: 24 EEQLKSMQAEMARLSLEKQL---AQVQEKLRLLSL--EKHGETSKCKDVEASKLMLQKEL 188 ++ ++ +Q E+ RL+ E A Q LSL EK KC+++E + EL Sbjct: 12 DQSVQDLQMEVERLTRELDQVSSASAQSAQYGLSLLEEKSALQQKCEELETLYDNTRHEL 71 Query: 189 EMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQR-KLEEEVSRHVEEKKALQHELSHI 365 ++ +E K + I +D +++ A+ L ++ E K L+HEL + Sbjct: 72 DITQEALTKFQTSQKVTNKTGIEQEDALLNESAARETSLNLQIFDLENELKQLRHELERV 131 Query: 366 XNDR 377 N+R Sbjct: 132 RNER 135
>MYH4_MOUSE (Q5SX39) Myosin-4 (Myosin heavy chain, skeletal muscle, fetal)| Length = 1939 Score = 35.8 bits (81), Expect = 0.046 Identities = 35/134 (26%), Positives = 68/134 (50%), Gaps = 13/134 (9%) Frame = +3 Query: 24 EEQLKSMQA---EMARLSLEKQLAQVQE-KLRLLSLEKHGETSKCKDVEASKLMLQ---- 179 E+ +K +Q E +L+L+ Q+Q+ + R+ LE E + +++EA K + + Sbjct: 1791 EQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELENEVENEQKRNIEAVKGLRKHERR 1850 Query: 180 -KELEMIREENRK----LDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKAL 344 KEL EE+RK L D ++ +LQ ++ + K + EE+ + ++ + + + Sbjct: 1851 VKELTYQTEEDRKNVLRLQD-------LVDKLQTKVKAYKRQAEEAEEQSNVNLAKFRKI 1903 Query: 345 QHELSHIXNDRGDV 386 QHEL +R D+ Sbjct: 1904 QHELEE-AEERADI 1916 Score = 35.0 bits (79), Expect = 0.079 Identities = 28/124 (22%), Positives = 52/124 (41%), Gaps = 7/124 (5%) Frame = +3 Query: 48 AEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELE----MIREENRK 215 A+ + + +E Q+ EKL+ E SK +D +A + LQK+++ I E + Sbjct: 1066 AQESTMDIENDKQQLDEKLKKKEFEMSNLQSKIEDEQALGMQLQKKIKELQARIEELEEE 1125 Query: 216 LDDQNHSSTSVIIRLQDEIISLKNAQRKLEE---EVSRHVEEKKALQHELSHIXNDRGDV 386 ++ + S + D L+ +LEE S +E K + E + D + Sbjct: 1126 IEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEA 1185 Query: 387 ERKH 398 +H Sbjct: 1186 TLQH 1189 Score = 33.1 bits (74), Expect = 0.30 Identities = 29/130 (22%), Positives = 59/130 (45%), Gaps = 7/130 (5%) Frame = +3 Query: 6 LSVSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGE-------TSKCKDVEAS 164 L + +Q E AE L K Q++ K++ L+ E T+K + +E Sbjct: 891 LQLQVQAEADGLADAEERCDQLIKTKIQLEAKIKELTERAEDEEEINAELTAKKRKLEDE 950 Query: 165 KLMLQKELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKAL 344 L+K+++ + K++ + H++ + + L +E+ L +E +++ +EKKAL Sbjct: 951 CSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGL-------DENIAKLTKEKKAL 1003 Query: 345 QHELSHIXND 374 Q +D Sbjct: 1004 QEAHQQTLDD 1013 Score = 30.4 bits (67), Expect = 1.9 Identities = 28/143 (19%), Positives = 63/143 (44%) Frame = +3 Query: 3 KLSVSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQK 182 K ++ E + K ++ +M L EK Q+Q + L E +C + +K+ L+ Sbjct: 864 KEDLAKSEAKRKELEEKMVALMQEKNDLQLQVQAEADGLADAEE--RCDQLIKTKIQLEA 921 Query: 183 ELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSH 362 +++ + E ++ N T+ +RKLE+E S ++ L+ L+ Sbjct: 922 KIKELTERAEDEEEINAELTA--------------KKRKLEDECSELKKDIDDLELTLAK 967 Query: 363 IXNDRGDVERKHFSIKEQIQAVN 431 + ++ E K ++ E++ ++ Sbjct: 968 VEKEKHATENKVKNLTEEMAGLD 990
>CJ118_MOUSE (Q8C9S4) Protein C10orf118 homolog (Oocyte-testis gene 1 protein)| Length = 917 Score = 35.8 bits (81), Expect = 0.046 Identities = 26/116 (22%), Positives = 51/116 (43%) Frame = +3 Query: 75 KQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIREENRKLDDQNHSSTSVII 254 K+L + K++ LS EK + E L +E+E ++EE Sbjct: 360 KELEKNTNKIKQLSQEKGRLQQLYESKEGETTRLIREIEKLKEE---------------- 403 Query: 255 RLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHIXNDRGDVERKHFSIKEQIQ 422 + ++I +K AQ KL+ E+ H E K L+ + + + + E+ + ++ I+ Sbjct: 404 -MNSQVIKVKWAQNKLKAEMDSHKETKDKLKETTTKLTQAKEEAEQIRQNCQDMIK 458 Score = 30.4 bits (67), Expect = 1.9 Identities = 28/138 (20%), Positives = 64/138 (46%), Gaps = 4/138 (2%) Frame = +3 Query: 3 KLSVSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQK 182 K + +E+++S+ + + L + + ++ +E LL EK TSK +++ LQ Sbjct: 573 KQEIEHLKEEMESLNSLINDLQKDIEGSRKRESELLLFTEKL--TSKNAQLQSESSALQS 630 Query: 183 ELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRK----LEEEVSRHVEEKKALQH 350 +++ + +L Q L+ +++ + +++ L+ E+S E KAL Sbjct: 631 QVDNLSCTESQLQSQCQQMGQANRNLESKLLKEEELRKEEVQTLQAELSAAQTEVKALST 690 Query: 351 ELSHIXNDRGDVERKHFS 404 ++ + ++ RKH S Sbjct: 691 QVEELKDELVTQRRKHAS 708
>BPAEA_MOUSE (Q91ZU8) Bullous pemphigoid antigen 1, isoform 5 (BPA)| (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin) Length = 2611 Score = 35.8 bits (81), Expect = 0.046 Identities = 35/151 (23%), Positives = 61/151 (40%), Gaps = 16/151 (10%) Frame = +3 Query: 21 QEEQLKSMQAEM--ARLSLEKQLAQVQEKLRLLSLEKHGETSKCK------DVEASKLML 176 +EE+LK E+ A EK++ +++ +L + LEK K + D + L Sbjct: 1320 KEEELKQQVDELTLANRKAEKEMRELKYELSAVQLEKASSEEKARLLKDKLDETNNTLKC 1379 Query: 177 QKE--------LEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEE 332 KE E ++ R L Q + +T ++ E LK + + E+ +E Sbjct: 1380 LKEDLERKDQAQERYSQQLRDLGGQLNQTTDKAEEVRQEANDLKKIKHTYQLELESLHQE 1439 Query: 333 KKALQHELSHIXNDRGDVERKHFSIKEQIQA 425 K LQ E+ + ER + Q+ A Sbjct: 1440 KGKLQREVDRVTRAHALAERNIQCLNSQVHA 1470 Score = 33.5 bits (75), Expect = 0.23 Identities = 27/93 (29%), Positives = 47/93 (50%), Gaps = 6/93 (6%) Frame = +3 Query: 12 VSIQEEQLKSMQAEMARL------SLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLM 173 VS+Q E ++ E A+L LE+QL +EK++ + KC+ +E L Sbjct: 1742 VSLQRENFRAQ--ENAKLWETNIRELERQLQCYREKMQQGPPVEANHYQKCRRLEEELLA 1799 Query: 174 LQKELEMIREENRKLDDQNHSSTSVIIRLQDEI 272 ++E+E +++ K+D Q ++RLQ EI Sbjct: 1800 QRREVENLKQ---KMDQQIKEHEHQLLRLQCEI 1829 Score = 32.0 bits (71), Expect = 0.67 Identities = 29/144 (20%), Positives = 62/144 (43%), Gaps = 28/144 (19%) Frame = +3 Query: 66 SLEKQLAQVQ---------------------EKLRLLSLEKHGETSKCKDVEASKLMLQK 182 SLE LAQ Q +++R LS E + + E + + Sbjct: 1610 SLEDDLAQSQNLVSEFKQKCDQQSMIIQKTEKEVRSLSAELSASKEEKRREEQKAQLQRA 1669 Query: 183 ELEMIREENRKLDDQNHSST-------SVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKA 341 +++ + + +++ D+ H T +I LQ+E K + + +++ + +E K Sbjct: 1670 QVQELNDRLKRVQDELHLKTIEEQMTHRKMILLQEESDKFKRSADEFRKKMEKLMESKVV 1729 Query: 342 LQHELSHIXNDRGDVERKHFSIKE 413 + +LS I +D ++R++F +E Sbjct: 1730 TETDLSGIKHDFVSLQRENFRAQE 1753 Score = 31.2 bits (69), Expect = 1.1 Identities = 29/124 (23%), Positives = 55/124 (44%), Gaps = 4/124 (3%) Frame = +3 Query: 18 IQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKEL--- 188 ++E+Q + E+ R+ Q +++LR + H +T +D L+ +L Sbjct: 1563 VREKQAIQQRCEVLRI----QADGFKDQLRNTNEHLHKQTKTEQDFHRKIKSLEDDLAQS 1618 Query: 189 -EMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHI 365 ++ E +K D Q S+II+ ++ + +A+ +E R E+K LQ Sbjct: 1619 QNLVSEFKQKCDQQ-----SMIIQKTEKEVRSLSAELSASKEEKRREEQKAQLQRAQVQE 1673 Query: 366 XNDR 377 NDR Sbjct: 1674 LNDR 1677
>CLPB2_SYNY3 (P74361) Chaperone clpB 2| Length = 872 Score = 35.8 bits (81), Expect = 0.046 Identities = 34/141 (24%), Positives = 68/141 (48%), Gaps = 3/141 (2%) Frame = +3 Query: 3 KLSVSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQK 182 K+ ++ + E+L + ++ +L +E+ LSL++ +++ + +E L+K Sbjct: 404 KMEITSKPEELDEVDRKILQLEMER-----------LSLQRENDSASKERLEK----LEK 448 Query: 183 ELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNA--QRKLE-EEVSRHVEEKKALQHE 353 EL +EE KL+ Q S +VI D+I ++K Q LE ++ R + KA + + Sbjct: 449 ELADFKEEQSKLNGQWQSEKTVI----DQIRTVKETIDQVNLEIQQAQRDYDYNKAAELQ 504 Query: 354 LSHIXNDRGDVERKHFSIKEQ 416 + + + VE + EQ Sbjct: 505 YGKLTDLQRQVEALETQLAEQ 525
>ITSN1_MOUSE (Q9Z0R4) Intersectin-1 (EH and SH3 domains protein 1)| Length = 1714 Score = 35.8 bits (81), Expect = 0.046 Identities = 32/132 (24%), Positives = 60/132 (45%), Gaps = 7/132 (5%) Frame = +3 Query: 21 QEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIR 200 ++EQ + Q E A +++ Q QE R L LEK +L Q+ELE R Sbjct: 376 RKEQERLAQLERAEQERKERERQEQEAKRQLELEK-------------QLEKQRELERQR 422 Query: 201 EENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVE-------EKKALQHELS 359 EE R+ + + + + Q ++ +N +++L + ++ E +K L+ EL Sbjct: 423 EEERRKEIERREAAKRELERQRQLEWERNRRQELLNQRNKEQEGTVVLKARRKTLEFELE 482 Query: 360 HIXNDRGDVERK 395 + + + +E K Sbjct: 483 ALNDKKHQLEGK 494
>MYH1_MOUSE (Q5SX40) Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1)| Length = 1942 Score = 35.8 bits (81), Expect = 0.046 Identities = 36/134 (26%), Positives = 68/134 (50%), Gaps = 13/134 (9%) Frame = +3 Query: 24 EEQLKSMQA---EMARLSLEKQLAQVQE-KLRLLSLEKHGETSKCKDVEASKLMLQ---- 179 E+ +K +Q E +L+L+ Q+Q+ + R+ LE E + ++VEA K + + Sbjct: 1794 EQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNVEAIKGLRKHERR 1853 Query: 180 -KELEMIREENRK----LDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKAL 344 KEL EE+RK L D ++ +LQ ++ + K + EE+ + ++ + + + Sbjct: 1854 VKELTYQTEEDRKNVLRLQD-------LVDKLQSKVKAYKRQAEEAEEQSNVNLAKFRKI 1906 Query: 345 QHELSHIXNDRGDV 386 QHEL +R D+ Sbjct: 1907 QHELEE-AEERADI 1919 Score = 34.7 bits (78), Expect = 0.10 Identities = 28/124 (22%), Positives = 52/124 (41%), Gaps = 7/124 (5%) Frame = +3 Query: 48 AEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELE----MIREENRK 215 A+ + + +E Q+ EKL+ E SK +D +A + LQK+++ I E + Sbjct: 1069 AQESTMDVENDKQQLDEKLKKKEFEMSNLQSKIEDEQALGMQLQKKIKELQARIEELEEE 1128 Query: 216 LDDQNHSSTSVIIRLQDEIISLKNAQRKLEE---EVSRHVEEKKALQHELSHIXNDRGDV 386 ++ + S + D L+ +LEE S +E K + E + D + Sbjct: 1129 IEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEA 1188 Query: 387 ERKH 398 +H Sbjct: 1189 TLQH 1192 Score = 32.7 bits (73), Expect = 0.39 Identities = 24/120 (20%), Positives = 57/120 (47%) Frame = +3 Query: 15 SIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEM 194 S+ + + + Q ++ LE ++ +V E+ T+K + +E L+K+++ Sbjct: 904 SLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDD 963 Query: 195 IREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHIXND 374 + K++ + H++ + + L +E+ L +E +++ +EKKALQ +D Sbjct: 964 LELTLAKVEKEKHATENKVKNLTEEMAGL-------DETIAKLTKEKKALQEAHQQTLDD 1016 Score = 32.0 bits (71), Expect = 0.67 Identities = 29/143 (20%), Positives = 65/143 (45%) Frame = +3 Query: 3 KLSVSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQK 182 K +++ E + K ++ +M L EK Q+Q + SL E +C + +K+ L+ Sbjct: 867 KENLAKAEAKRKELEEKMVALMQEKNDLQLQVQSEADSLADAEE--RCDQLIKTKIQLEA 924 Query: 183 ELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSH 362 +++ + E ++ N T+ +RKLE+E S ++ L+ L+ Sbjct: 925 KIKEVTERAEDEEEINAELTA--------------KKRKLEDECSELKKDIDDLELTLAK 970 Query: 363 IXNDRGDVERKHFSIKEQIQAVN 431 + ++ E K ++ E++ ++ Sbjct: 971 VEKEKHATENKVKNLTEEMAGLD 993 Score = 28.5 bits (62), Expect = 7.4 Identities = 28/143 (19%), Positives = 60/143 (41%), Gaps = 7/143 (4%) Frame = +3 Query: 6 LSVSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLL--SLEKHGETSKCKDVEASKLMLQ 179 L + ++ + + + +K LA+ ++K LE + S+ E K+ Sbjct: 1435 LMIDVERTNAACAALDKKQRNFDKILAEWKQKYEETHAELEASQKESRSLSTELFKIKNA 1494 Query: 180 KE-----LEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKAL 344 E LE ++ EN+ L + T I I L+ ++++E+E S E + AL Sbjct: 1495 YEESLDHLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQIEQEKS---ELQAAL 1551 Query: 345 QHELSHIXNDRGDVERKHFSIKE 413 + + + ++ G + R + + Sbjct: 1552 EEAEASLEHEEGKILRIQLELNQ 1574
>CTRO_HUMAN (O14578) Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK)| (Rho-interacting, serine/threonine-protein kinase 21) Length = 2027 Score = 35.8 bits (81), Expect = 0.046 Identities = 33/160 (20%), Positives = 75/160 (46%), Gaps = 22/160 (13%) Frame = +3 Query: 3 KLSVSIQEEQLKSMQAEMARLS---------LEKQLAQVQEKLRLLSLEKHGETSKCKDV 155 +LS+ +E QL ++QA A L LE+ A+ +E+++ L+ + K + Sbjct: 880 QLSLQERESQLTALQAARAALESQLRQAKTELEETTAEAEEEIQALTAHRDEIQRKFDAL 939 Query: 156 EASKLM---LQKELEMIREENRKLDDQN----------HSSTSVIIRLQDEIISLKNAQR 296 S + L+++L + E+N +L++QN + I++L+ E+ L+ Sbjct: 940 RNSCTVITDLEEQLNQLTEDNAELNNQNFYLSKQLDEASGANDEIVQLRSEVDHLRREIT 999 Query: 297 KLEEEVSRHVEEKKALQHELSHIXNDRGDVERKHFSIKEQ 416 + E +++ + +AL+ + + D+E + + E+ Sbjct: 1000 EREMQLTSQKQTMEALKTTCTMLEEQVMDLEALNDELLEK 1039 Score = 31.2 bits (69), Expect = 1.1 Identities = 31/108 (28%), Positives = 52/108 (48%), Gaps = 21/108 (19%) Frame = +3 Query: 111 LSLEKHGETSKCKDVEASKLMLQKELEMIREE--NRKLDDQNHSST----------SVII 254 L+LEK E ++C ++E + + EL REE +RK D H ST S I+ Sbjct: 1263 LALEK--EKARCAELEEALQKTRIELRSAREEAAHRKATDHPHPSTPATARQQIAMSAIV 1320 Query: 255 RLQD------EIISLKNAQRK---LEEEVSRHVEEKKALQHELSHIXN 371 R + +++ +++RK EE SR ++E+ + H + H N Sbjct: 1321 RSPEHQPSAMSLLAPPSSRRKESSTPEEFSRRLKER--MHHNIPHRFN 1366
>SMC5_YEAST (Q08204) Structural maintenance of chromosome 5| Length = 1093 Score = 35.8 bits (81), Expect = 0.046 Identities = 16/54 (29%), Positives = 29/54 (53%) Frame = +3 Query: 252 IRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHIXNDRGDVERKHFSIKE 413 IR+++EII+LKN + + +K +HELS + + D+ R+ + E Sbjct: 657 IRIENEIINLKNEYNDRKSTLDALSNQKSGYRHELSELASKNDDINREAHQLNE 710 Score = 30.0 bits (66), Expect = 2.5 Identities = 33/126 (26%), Positives = 59/126 (46%), Gaps = 4/126 (3%) Frame = +3 Query: 66 SLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIREENRKLDDQNHSSTS 245 +LE Q+ ++ EK L K E K K+ + +++ ++L IR+E K +QN Sbjct: 312 TLENQVEELTEKCSL----KTDEFLKAKE-KINEIF--EKLNTIRDEVIKKKNQNEYYRG 364 Query: 246 VIIRLQDEIISLKNAQRKLEEEVSR-HVEEKKALQH---ELSHIXNDRGDVERKHFSIKE 413 +LQ IIS K + +E +++ H+ EK + + I N G++ I Sbjct: 365 RTKKLQATIISTKEDFLRSQEILAQTHLPEKSVFEDIDIKRKEIINKEGEIRDLISEIDA 424 Query: 414 QIQAVN 431 + A+N Sbjct: 425 KANAIN 430
>ALM1_SCHPO (Q9UTK5) Abnormal long morphology protein 1 (Sp8)| Length = 1727 Score = 35.4 bits (80), Expect = 0.061 Identities = 34/135 (25%), Positives = 60/135 (44%), Gaps = 15/135 (11%) Frame = +3 Query: 69 LEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIREE--------NRKLDD 224 LE L+ +Q K L + + + ++A+ + ++ +E ++ E + L+ Sbjct: 917 LESSLSDLQSKHTSLESQYNYSLRNIEQLQAASKLAEEMVERVKTEYDEYRLQTSESLEK 976 Query: 225 QNHSSTSV---IIRLQDEIIS----LKNAQRKLEEEVSRHVEEKKALQHELSHIXNDRGD 383 + TS+ I+ LQDEI S +N + E V+ +EE K L +ELS N Sbjct: 977 NHLKITSLEQRIVILQDEIASSSLRCENITKDSETRVALLLEENKHLNNELSSHRNAEKQ 1036 Query: 384 VERKHFSIKEQIQAV 428 K K+Q+ V Sbjct: 1037 HLEKENDYKQQLLLV 1051 Score = 33.5 bits (75), Expect = 0.23 Identities = 28/138 (20%), Positives = 68/138 (49%), Gaps = 10/138 (7%) Frame = +3 Query: 12 VSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEA---SKLMLQK 182 V++ E KS++ + R E+ + +++EK+ L + + +E+ ++ K Sbjct: 1232 VALLNESNKSLRENLERN--EEVITELREKIETLKTDLANFRLNKEQLESQLQTEKAAVK 1289 Query: 183 ELEMIREENRKLDDQ-------NHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKA 341 +LE EE ++ + + + S++S RL++E++S +N +L +E+ E + Sbjct: 1290 KLENSNEEYKRHNQEILLSLNSSTSTSSDASRLKNELVSKENLIEELNQEIGHLKSELET 1349 Query: 342 LQHELSHIXNDRGDVERK 395 ++ + + N+R + K Sbjct: 1350 VKSKSEDLENERAQNQSK 1367 Score = 30.0 bits (66), Expect = 2.5 Identities = 35/158 (22%), Positives = 72/158 (45%), Gaps = 21/158 (13%) Frame = +3 Query: 12 VSIQEEQLKSM--QAEMARL----------SLEKQLAQVQEKLRLLSLEK------HGET 137 ++ E+QL+S QAE +R SL+ L ++ L+ E + E Sbjct: 72 INFLEQQLQSSNNQAEESRNLISVLRNENESLKTNLENQNKRFDALTTENQSLRRANSEL 131 Query: 138 SKCKDVEASKLMLQKE-LEMIREENRKLDDQNHSSTSVIIRLQDEIIS--LKNAQRKLEE 308 + + + +L + K+ +E ++ EN L +Q S+ + +++ ++ +++E Sbjct: 132 QEQSKIASEQLSIAKDQIEALQNENSHLGEQVQSAHQALSDIEERKKQHMFASSSSRVKE 191 Query: 309 EVSRHVEEKKALQHELSHIXNDRGDVERKHFSIKEQIQ 422 E+ V+EK AL +L+ + +D V K Q+Q Sbjct: 192 EIL--VQEKSALVSDLASLQSDHSKVCEKLEVSSRQVQ 227
>Y864_MYCCT (P43047) Hypothetical protein MCAP_0864 precursor (ORF R8)| Length = 470 Score = 35.4 bits (80), Expect = 0.061 Identities = 26/94 (27%), Positives = 48/94 (51%), Gaps = 4/94 (4%) Frame = +3 Query: 69 LEKQLAQVQEKLRLLSL---EKHGETSKCKDVEASK-LMLQKELEMIREENRKLDDQNHS 236 LEKQL +++++ LL+ EK E K + + K + L LE I KLD Sbjct: 219 LEKQLLELKQQTSLLTKTKEEKQAEIDKQETILKDKQIQLSNLLEEINNNKTKLD----Q 274 Query: 237 STSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKK 338 S + ++ + +I +++ + +E+S+ EEK+ Sbjct: 275 SDNELVNINQQIRDIESQIQNTNDEISKLKEEKE 308
>LUZP1_MOUSE (Q8R4U7) Leucine zipper protein 1 (Leucine zipper motif-containing| protein) Length = 1068 Score = 35.4 bits (80), Expect = 0.061 Identities = 37/154 (24%), Positives = 72/154 (46%), Gaps = 23/154 (14%) Frame = +3 Query: 30 QLKSMQAEMARLS-LEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIREE 206 ++K +++ RL E+ L EKL+ L+L E + E + KEL E+ Sbjct: 161 KVKELESSEDRLDKTEQSLVSELEKLKSLTLSFVNERKYLNEKEKENEKIIKELTQKLEQ 220 Query: 207 NRKLDDQNHSSTSVI-----IRLQDEI---ISLKNAQRK--------LEEEVSRHVEEKK 338 N+K++ + + S +R++D I +S K ++RK +E E E +K Sbjct: 221 NKKMNRDHMRNASTFLERNDLRIEDGISSTLSSKESKRKGSLDYLKQVENETRDKSENEK 280 Query: 339 ALQHELSHIXNDRGDVER-----KHF-SIKEQIQ 422 E + + + ++E+ KHF S++E+++ Sbjct: 281 NRNQEDNKVKDLNQEIEKLKTQIKHFESLEEELK 314 Score = 28.1 bits (61), Expect = 9.7 Identities = 30/144 (20%), Positives = 61/144 (42%), Gaps = 12/144 (8%) Frame = +3 Query: 21 QEEQLKSMQAEMARL--------SLEKQLAQVQEKLRLLS----LEKHGETSKCKDVEAS 164 ++ ++K + E+ +L SLE++L +++ K L E + S +E Sbjct: 285 EDNKVKDLNQEIEKLKTQIKHFESLEEELKKMRAKNNDLQDNYLTELNRNRSLASQLEEI 344 Query: 165 KLMLQKELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKAL 344 KL ++K+ E+ D ++ R + E LK E VS+H + + Sbjct: 345 KLQVRKQKELGN------GDIEGEDAFLLGRGRHERTKLKG--HGSEASVSKHTSRELSP 396 Query: 345 QHELSHIXNDRGDVERKHFSIKEQ 416 QH+ + N + +H+S+ + Sbjct: 397 QHKRERLRNREFALSNEHYSLSSK 420
>M6B_STRP6 (P08089) M protein, serotype 6 precursor| Length = 483 Score = 35.4 bits (80), Expect = 0.061 Identities = 20/65 (30%), Positives = 34/65 (52%) Frame = +3 Query: 204 ENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHIXNDRGD 383 EN+ L DQN + T+ L D+ +L ++L+ E +R E K L +LS + + Sbjct: 94 ENKNLTDQNKNLTTENKNLTDQNKNLTTENKELKAEENRLTTENKGLTKKLSEAEEEAAN 153 Query: 384 VERKH 398 ER++ Sbjct: 154 KEREN 158 Score = 34.3 bits (77), Expect = 0.13 Identities = 24/89 (26%), Positives = 41/89 (46%) Frame = +3 Query: 150 DVEASKLMLQKELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVE 329 DVE S MLQ + + EN L DQN + T+ L D+ +L + L ++ Sbjct: 64 DVENS--MLQANNDKLTTENNNLTDQNKNLTTENKNLTDQNKNLTTENKNLTDQNKNLTT 121 Query: 330 EKKALQHELSHIXNDRGDVERKHFSIKEQ 416 E K L+ E + + + + +K +E+ Sbjct: 122 ENKELKAEENRLTTENKGLTKKLSEAEEE 150
>MYT1L_HUMAN (Q9UL68) Myelin transcription factor 1-like protein (MyT1L protein)| (MyT1-L) Length = 1186 Score = 35.4 bits (80), Expect = 0.061 Identities = 15/62 (24%), Positives = 41/62 (66%) Frame = +3 Query: 180 KELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELS 359 +E++ + EE ++L++ N + +I+L+ +I ++++ + +EEE ++ ++L HEL+ Sbjct: 1063 EEIKQLDEEIKELNESNSQMEADMIKLRTQITTMESNLKTIEEENKVIEQQNESLLHELA 1122 Query: 360 HI 365 ++ Sbjct: 1123 NL 1124
>TPM1_RANTE (P13105) Tropomyosin 1 alpha chain (Alpha-tropomyosin)| Length = 284 Score = 35.4 bits (80), Expect = 0.061 Identities = 23/87 (26%), Positives = 41/87 (47%) Frame = +3 Query: 168 LMLQKELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQ 347 L L KE + R E + D + S +L+DE+++++ + E+E+ ++ E K Q Sbjct: 11 LKLDKENALDRAEQAEADKKGAEDKSK--QLEDELVAMQKKMKGTEDELDKYSEALKDAQ 68 Query: 348 HELSHIXNDRGDVERKHFSIKEQIQAV 428 +L D E S+ +IQ V Sbjct: 69 EKLELAEKKATDAEADVASLNRRIQLV 95 Score = 33.5 bits (75), Expect = 0.23 Identities = 27/108 (25%), Positives = 51/108 (47%) Frame = +3 Query: 51 EMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIREENRKLDDQN 230 E A LS E + A+++E+L+ + T+ K +EA ++ + EE + L D+ Sbjct: 181 ERAELS-ESKCAELEEELKTV-------TNNLKSLEAQAEKYSQKEDKYEEEIKVLTDKL 232 Query: 231 HSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHIXND 374 + + + + L+ + LE+E+ + KA+ EL H ND Sbjct: 233 KEAETRAEFAERTVAKLEKSIDDLEDELYAQKLKYKAISEELDHALND 280
>TPM1_PIG (P42639) Tropomyosin 1 alpha chain (Alpha-tropomyosin)| Length = 284 Score = 35.4 bits (80), Expect = 0.061 Identities = 24/111 (21%), Positives = 50/111 (45%) Frame = +3 Query: 90 VQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIREENRKLDDQNHSSTSVIIRLQDE 269 +++K+++L L+K + + EA K + +D++ +L+DE Sbjct: 4 IKKKMQMLKLDKENALDRADEAEADK--------------KAAEDRSK-------QLEDE 42 Query: 270 IISLKNAQRKLEEEVSRHVEEKKALQHELSHIXNDRGDVERKHFSIKEQIQ 422 ++SL+ + E+E+ ++ E K Q +L D E S+ +IQ Sbjct: 43 LVSLQKKLKATEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQ 93 Score = 33.5 bits (75), Expect = 0.23 Identities = 27/108 (25%), Positives = 51/108 (47%) Frame = +3 Query: 51 EMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIREENRKLDDQN 230 E A LS E + A+++E+L+ + T+ K +EA ++ + EE + L D+ Sbjct: 181 ERAELS-EGKCAELEEELKTV-------TNNLKSLEAQAEKYSQKEDKYEEEIKVLSDKL 232 Query: 231 HSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHIXND 374 + + + + L+ + LE+E+ + KA+ EL H ND Sbjct: 233 KEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALND 280
>MFP1_ARATH (Q9LW85) MAR binding filament-like protein 1| Length = 726 Score = 35.4 bits (80), Expect = 0.061 Identities = 29/148 (19%), Positives = 64/148 (43%), Gaps = 10/148 (6%) Frame = +3 Query: 18 IQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMI 197 ++EE+ + +EKQ+ +E + L + ++ + +L +ELE + Sbjct: 559 LEEEKKTVLSLNKEVKGMEKQILMEREARKSLETDLEEAVKSLDEMNKNTSILSRELEKV 618 Query: 198 REENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEV-SRHV------EEKKALQHEL 356 L+D+ LQ + KNA ++ +E V H+ +E++ L+ ++ Sbjct: 619 NTHASNLEDEKEV-------LQRSLGEAKNASKEAKENVEDAHILVMSLGKEREVLEKKV 671 Query: 357 SHIXNDRGDVERKHFSIKEQ---IQAVN 431 + D G + + ++ Q ++AVN Sbjct: 672 KKLEEDLGSAKGEILRMRSQPDSVKAVN 699
>MYT1L_MOUSE (P97500) Myelin transcription factor 1-like protein (MyT1L protein)| (Postmitotic neural gene 1 protein) (Zinc finger protein Png-1) (Neural zinc finger factor 1) (NZF-1) Length = 1187 Score = 35.4 bits (80), Expect = 0.061 Identities = 15/62 (24%), Positives = 41/62 (66%) Frame = +3 Query: 180 KELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELS 359 +E++ + EE ++L++ N + +I+L+ +I ++++ + +EEE ++ ++L HEL+ Sbjct: 1064 EEIKQLDEEIKELNESNSQMEADMIKLRTQITTMESNLKTIEEENKVIEQQNESLLHELA 1123 Query: 360 HI 365 ++ Sbjct: 1124 NL 1125
>LRC45_HUMAN (Q96CN5) Leucine-rich repeat-containing protein 45| Length = 670 Score = 35.4 bits (80), Expect = 0.061 Identities = 36/137 (26%), Positives = 60/137 (43%), Gaps = 6/137 (4%) Frame = +3 Query: 24 EEQLKSMQA-----EMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKEL 188 EE K+MQ E ARLSLE++L++V K LS E K ++L Q+ L Sbjct: 445 EESEKAMQERVQRLEAARLSLEEELSRV--KAAALSERGQAEEELIKAKSQARLEEQQRL 502 Query: 189 EMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHIX 368 + ++ R L + ++ + + + +L +V + LQ ELS Sbjct: 503 AHLEDKLRLLAQARDEAQGACLQQKQVVAEAQTRVSQLGLQVEGLRRRLEELQQELSLKD 562 Query: 369 NDR-GDVERKHFSIKEQ 416 +R +V R ++EQ Sbjct: 563 QERVAEVSRVRVELQEQ 579 Score = 33.9 bits (76), Expect = 0.18 Identities = 43/153 (28%), Positives = 78/153 (50%), Gaps = 20/153 (13%) Frame = +3 Query: 24 EEQLKSMQAEMARLSLEKQLAQVQEKLRLLSL---EKHGETSKCKDVEA------SKLML 176 EE+L +++ ARL +++LA +++KLRLL+ E G + K V A S+L L Sbjct: 484 EEELIKAKSQ-ARLEEQQRLAHLEDKLRLLAQARDEAQGACLQQKQVVAEAQTRVSQLGL 542 Query: 177 QKE-----LEMIREENRKLDDQNHSSTS-VIIRLQDEIISLKNAQRKLEEEVSRHVEEK- 335 Q E LE +++E D + + S V + LQ++ N + + E + EK Sbjct: 543 QVEGLRRRLEELQQELSLKDQERVAEVSRVRVELQEQ-----NGRLQAELAAQEALREKA 597 Query: 336 KALQHELSHIXNDRG----DVERKHFSIKEQIQ 422 AL+ +L + +D D E ++ S++E+++ Sbjct: 598 AALERQLKVMASDHREALLDRESENASLREKLR 630
>MYO3_SCHPO (O14157) Myosin type-2 heavy chain 2 (Myosin type II heavy chain 2)| Length = 2104 Score = 35.4 bits (80), Expect = 0.061 Identities = 27/133 (20%), Positives = 61/133 (45%), Gaps = 3/133 (2%) Frame = +3 Query: 12 VSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELE 191 V ++EE+ K+++ + ++ ++ K L LEK T+ K+ +LQ +L+ Sbjct: 1755 VQLEEEREKNLRIRQDNRHMHAEIGDIRTKFDELVLEK---TNLLKE----NSILQADLQ 1807 Query: 192 MIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQ---HELSH 362 + N ++ S ++ L ++ ++ A + L ++ + E + L+ HE+S Sbjct: 1808 SLSRVNNSSSTAQQNAQSQLLSLTAQLQEVREANQTLRKDQDTLLRENRNLERKLHEVSE 1867 Query: 363 IXNDRGDVERKHF 401 N + D + F Sbjct: 1868 QLNKKFDSSARPF 1880 Score = 28.9 bits (63), Expect = 5.7 Identities = 24/125 (19%), Positives = 59/125 (47%), Gaps = 3/125 (2%) Frame = +3 Query: 66 SLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIREENRKLD--DQNHSS 239 +L+ QL +E L++ K D++ + + ++ ++ N +++ + SS Sbjct: 847 NLQNQLESTKEVANELTITKERVLQLTNDLQEEQALAHEKDILVERANSRVEVVHERLSS 906 Query: 240 TSVIIRLQDEIISLKNAQRK-LEEEVSRHVEEKKALQHELSHIXNDRGDVERKHFSIKEQ 416 + + DE A+++ +EE+++ Q E+S++ + +E+K SIK+ Sbjct: 907 LENQVTIADEKYEFLYAEKQSIEEDLANK-------QTEISYLSDLSSTLEKKLSSIKKD 959 Query: 417 IQAVN 431 Q ++ Sbjct: 960 EQTIS 964
>MYH8_RAT (P04462) Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal)| (MyHC-perinatal) (Fragment) Length = 257 Score = 35.4 bits (80), Expect = 0.061 Identities = 37/134 (27%), Positives = 67/134 (50%), Gaps = 13/134 (9%) Frame = +3 Query: 24 EEQLKSMQA---EMARLSLEKQLAQVQE-KLRLLSLEKHGETSKCKDVEASKLMLQ---- 179 E+ +K +Q E +L+L+ Q+Q+ + R+ LE E + ++ EA K + + Sbjct: 110 EQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERR 169 Query: 180 -KELEMIREENRK----LDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKAL 344 KEL EE+RK L D ++ +LQ ++ S K + EE+ + ++ + + L Sbjct: 170 VKELTYQTEEDRKNVLRLQD-------LVDKLQAKVKSYKRQAEEAEEQSNVNLAKFRKL 222 Query: 345 QHELSHIXNDRGDV 386 QHEL +R D+ Sbjct: 223 QHELEE-AEERADI 235
>GOGA3_MOUSE (P55937) Golgin subfamily A member 3 (Golgin-160) (Male-enhanced| antigen 2) (MEA-2) Length = 1487 Score = 35.4 bits (80), Expect = 0.061 Identities = 31/147 (21%), Positives = 74/147 (50%), Gaps = 10/147 (6%) Frame = +3 Query: 12 VSIQEEQLKSMQAEMARLSLEKQLAQVQEKL--RLLSLEKHGETSKCKD-----VEASKL 170 ++++ Q++ +Q E A +L KQ+ +V+E+ + + +E + + KD ++A+K Sbjct: 813 LAVKSNQVEHLQQETA--TLRKQMQKVKEQFVQQKVMVEAYRRDATSKDQLINELKATKK 870 Query: 171 MLQKELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQH 350 L E++ +R+E KL + + RLQ ++ + +LE + +E+ ++ Sbjct: 871 RLDSEMKELRQELIKLQGEKKTVEVEHSRLQKDMSLVHQQMAELEGHLQSVQKERDEMEI 930 Query: 351 ELSHIXNDRGD---VERKHFSIKEQIQ 422 L + D+ + + ++K+QI+ Sbjct: 931 HLQSLKFDKEQMIALTEANETLKKQIE 957 Score = 29.6 bits (65), Expect = 3.3 Identities = 25/135 (18%), Positives = 59/135 (43%) Frame = +3 Query: 24 EEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIRE 203 E Q++++ E ++ EK A++Q +L LS + + + L E++ +++ Sbjct: 414 EGQVEALSLEASQALQEK--AELQAQLAALSTRLQAQVEHSHSSQQKQDSLSSEVDTLKQ 471 Query: 204 ENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHIXNDRGD 383 L S++ + S N + EE+ R + + + +Q + N D Sbjct: 472 SCWDLGRAMTDLQSMLEAKNASLASSNNDLQVAEEQYQRLMAKVEDMQRNILSKDNTVHD 531 Query: 384 VERKHFSIKEQIQAV 428 + ++ +++ Q+Q V Sbjct: 532 LRQQMTALQSQLQQV 546
>MYSP_DIRIM (P13392) Paramyosin (Fragment)| Length = 848 Score = 35.4 bits (80), Expect = 0.061 Identities = 29/124 (23%), Positives = 54/124 (43%) Frame = +3 Query: 24 EEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIRE 203 EEQ++ M ++++L K Q + ++ ++ LEK T +E +K L+K + ++ Sbjct: 306 EEQIEIMLQKISQLEKAKSRLQSEVEVLIVDLEKAQNTIAI--LERAKEQLEKTVNELKV 363 Query: 204 ENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHIXNDRGD 383 +L + ++ E+ +KN K E+ E K LQ +L D Sbjct: 364 RIDELTVELEAAQREARAALAELQKMKNLYEKAIEQKEALARENKKLQDDLHEAKEALAD 423 Query: 384 VERK 395 RK Sbjct: 424 ANRK 427 Score = 33.5 bits (75), Expect = 0.23 Identities = 26/100 (26%), Positives = 49/100 (49%), Gaps = 2/100 (2%) Frame = +3 Query: 18 IQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMI 197 + EEQ SM+ + R SLE+Q+ Q+Q ++ + ++ + K ++ K I Sbjct: 675 LHEEQEHSMKIDALRKSLEEQVKQLQVQI---------QEAEAAALLGGKRVIAKLETRI 725 Query: 198 REENRKLDDQ--NHSSTSVIIRLQDEIISLKNAQRKLEEE 311 R+ LD++ H T +R +D +K Q +++EE Sbjct: 726 RDLETALDEETRRHKETQGALRKKDR--RIKEVQMQVDEE 763 Score = 30.4 bits (67), Expect = 1.9 Identities = 33/130 (25%), Positives = 60/130 (46%), Gaps = 12/130 (9%) Frame = +3 Query: 21 QEEQLKSMQAEMARLS--LEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEM 194 Q E + +AE+ +L LE+ + ++ + +L +KH + C D LQK+ Sbjct: 65 QIESNRKREAELQKLRKLLEESQLENEDAMNVLR-KKHQDA--CLDYAEQIEQLQKKNSK 121 Query: 195 IREENRKLDDQNHSSTSVIIRLQ-DEIISLKNAQR---------KLEEEVSRHVEEKKAL 344 I E ++L + T+ I +LQ D+ ++ K A+R E+++RHV + Sbjct: 122 IDRERQRLQHEVIELTATIDQLQKDKHLAEKAAERFEAQTIELSNKVEDLNRHVNDLAQQ 181 Query: 345 QHELSHIXND 374 + L ND Sbjct: 182 RQRLQAENND 191 Score = 28.9 bits (63), Expect = 5.7 Identities = 21/92 (22%), Positives = 43/92 (46%) Frame = +3 Query: 69 LEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIREENRKLDDQNHSSTSV 248 L +Q ++Q + L E H + + +++ K L ++LE E R+L+D + + Sbjct: 178 LAQQRQRLQAENNDLLKEIHDQKVQLDNLQHVKYQLAQQLE---EARRRLEDAERERSQL 234 Query: 249 IIRLQDEIISLKNAQRKLEEEVSRHVEEKKAL 344 +L + L + + L+EE + E + L Sbjct: 235 QAQLHQVQLELDSVRTALDEESAARAEAEHKL 266
>SMC4_MOUSE (Q8CG47) Structural maintenance of chromosomes 4-like 1 protein| (Chromosome-associated polypeptide C) (XCAP-C homolog) Length = 1286 Score = 35.4 bits (80), Expect = 0.061 Identities = 26/126 (20%), Positives = 57/126 (45%), Gaps = 5/126 (3%) Frame = +3 Query: 3 KLSVSIQEEQLKSMQAEMARLS-----LEKQLAQVQEKLRLLSLEKHGETSKCKDVEASK 167 ++++ + LK Q + R EK++ ++ +L+ + + + K E S Sbjct: 922 QVAIKTADRNLKKAQDSVCRTEKEIKDTEKEINDLKTELKNIEDKAEEVINNTKTAETSL 981 Query: 168 LMLQKELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQ 347 +QKE + +E + + + H+ LQ + +S+K +++ +S H + K Q Sbjct: 982 PEIQKEHRNLLQELKVIQENEHA-------LQKDALSIKLKLEQIDGHISEHNSKIKYWQ 1034 Query: 348 HELSHI 365 E+S I Sbjct: 1035 KEISKI 1040
>GR1_ARATH (Q9ZRT1) Protein gamma response 1 (Protein gamma response I)| Length = 589 Score = 35.4 bits (80), Expect = 0.061 Identities = 36/143 (25%), Positives = 73/143 (51%), Gaps = 8/143 (5%) Frame = +3 Query: 18 IQEEQLKSMQAEMARLSLEKQLAQVQEK-LRLLSLEKHGETSKCKDVEASKL------ML 176 I+E ++++ Q + + L ++L + LRL SL+ + + K K SK+ + Sbjct: 80 IEELKVENQQIKSDKEKLAEELGKTASMPLRLTSLQGYIDHLKKKMKSRSKMVGDARDLY 139 Query: 177 QKELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKL-EEEVSRHVEEKKALQHE 353 + +E+++ + LD+ + ++I+ E+ SLK L EEE+S+ + L + Sbjct: 140 YRLVELLQVKG--LDELSEDGINMIV---SEVKSLKMKTEFLQEEELSKKTLVTENLLKK 194 Query: 354 LSHIXNDRGDVERKHFSIKEQIQ 422 L ++ + D ERK S++E+ Q Sbjct: 195 LEYLSTEAADGERKLSSVEEEKQ 217
>EVPL_HUMAN (Q92817) Envoplakin (210 kDa paraneoplastic pemphigus antigen) (p210)| (210 kDa cornified envelope precursor protein) Length = 2033 Score = 35.0 bits (79), Expect = 0.079 Identities = 25/92 (27%), Positives = 49/92 (53%) Frame = +3 Query: 45 QAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIREENRKLDD 224 + + AR +++ ++Q++LR L +K +T + + E SKL+ QK E R++ + Sbjct: 1580 ELQRARDQADQECGRLQQELRALERQKQQQTLQLQ--EESKLLSQKT-ESERQKAAQRGQ 1636 Query: 225 QNHSSTSVIIRLQDEIISLKNAQRKLEEEVSR 320 + + I+R +D+I + R L +VSR Sbjct: 1637 ELSRLEAAILREKDQIYEKERTLRDLHAKVSR 1668 Score = 29.3 bits (64), Expect = 4.3 Identities = 25/97 (25%), Positives = 48/97 (49%) Frame = +3 Query: 24 EEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIRE 203 +EQL +Q E R ++ A+V+ K + +H + +L+KE E +R+ Sbjct: 1288 QEQLIRLQGE--RDEWRRERAKVETKTVSKEVVRHEKDP----------VLEKEAERLRQ 1335 Query: 204 ENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEV 314 E R+ + ++ + LQ + + L+ +RK EE+V Sbjct: 1336 EVREAAQKRRAAEDAVYELQSKRLLLE--RRKPEEKV 1370
>BEGIN_RAT (O88881) Brain-enriched guanylate kinase-associated protein| Length = 611 Score = 35.0 bits (79), Expect = 0.079 Identities = 30/124 (24%), Positives = 66/124 (53%), Gaps = 9/124 (7%) Frame = +3 Query: 48 AEMARLS-LEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIREENRKLDD 224 A+M +LS L++Q +++++L S H + ++++ L+ EL +EE K+ Sbjct: 18 ADMEKLSALQEQKGELRKRL---SYTTHKLEKLETEFDSTRHYLEIELRRAQEELDKV-- 72 Query: 225 QNHSSTSVIIRLQDEIISLKNAQRKLEEEVSR----HVEEKKALQHEL----SHIXNDRG 380 T + R+Q ++L+ ++LE+++ R + EEK+A+ HE+ SH+ + Sbjct: 73 -----TEKLRRIQSNYMALQRINQELEDKLYRMGQHYEEEKRAMSHEIVALNSHLLEAKV 127 Query: 381 DVER 392 +++ Sbjct: 128 TIDK 131
>CENPF_HUMAN (P49454) CENP-F kinetochore protein (Centromere protein F) (Mitosin)| (AH antigen) Length = 3210 Score = 35.0 bits (79), Expect = 0.079 Identities = 31/141 (21%), Positives = 64/141 (45%), Gaps = 4/141 (2%) Frame = +3 Query: 6 LSVSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKE 185 L+ ++ EQ + + + + LE L ++Q LSLEK K++ + + ++E Sbjct: 916 LNDKVETEQAEIQELKKSNHLLEDSLKELQLLSETLSLEK-------KEMSSIISLNKRE 968 Query: 186 LEMIREENRKLDDQNHSSTSVIIRLQDEIISLKN----AQRKLEEEVSRHVEEKKALQHE 353 +E + +EN L + N S + L + S N ++ + E ++ +EK L Sbjct: 969 IEELTQENGTLKEINASLNQEKMNLIQKSESFANYIDEREKSISELSDQYKQEKLILLQR 1028 Query: 354 LSHIXNDRGDVERKHFSIKEQ 416 N D+ +K+ + +E+ Sbjct: 1029 CEETGNAYEDLSQKYKAAQEK 1049 Score = 33.5 bits (75), Expect = 0.23 Identities = 29/111 (26%), Positives = 49/111 (44%), Gaps = 1/111 (0%) Frame = +3 Query: 3 KLSVSIQEEQLKSMQAEMARLS-LEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQ 179 K + I EE K+ + ++ L+K+ + Q K++LL CK +E K +LQ Sbjct: 2857 KATTQILEELKKTKMDNLKYVNQLKKENERAQGKMKLL-------IKSCKQLEEEKEILQ 2909 Query: 180 KELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEE 332 KEL ++ K T V L EI LK + +E ++++ Sbjct: 2910 KELSQLQAAQEKQKTGTVMDTKV-DELTTEIKELKETLEEKTKEADEYLDK 2959
>TRIPB_HUMAN (Q15643) Thyroid receptor-interacting protein 11 (TRIP-11)| (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution related gene on chromosome 14) Length = 1979 Score = 35.0 bits (79), Expect = 0.079 Identities = 33/139 (23%), Positives = 64/139 (46%), Gaps = 7/139 (5%) Frame = +3 Query: 24 EEQLKSMQAEMARLSLEKQ---LAQVQEKLRL----LSLEKHGETSKCKDVEASKLMLQK 182 ++ L + E+ RLS Q LA+ KL++ L EK + + ++++ S L L Sbjct: 391 QQALSDAENEIMRLSSLNQDNSLAEDNLKLKMRIEVLEKEKSLLSQEKEELQMSLLKLNN 450 Query: 183 ELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSH 362 E E+I+ S+ + I L E+ L+ E+E+++ + EK+ L E+ Sbjct: 451 EYEVIK-----------STATRDISLDSELHDLRLNLEAKEQELNQSISEKETLIAEIEE 499 Query: 363 IXNDRGDVERKHFSIKEQI 419 + + + IK+Q+ Sbjct: 500 LDRQNQEATKHMILIKDQL 518 Score = 32.7 bits (73), Expect = 0.39 Identities = 28/101 (27%), Positives = 44/101 (43%), Gaps = 1/101 (0%) Frame = +3 Query: 24 EEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIRE 203 +E+ +Q E+ + S Q + E LR EK K+ LQ+ELE +RE Sbjct: 821 KERSSKLQEELDKYS---QALRKNEILRQTIEEKDRSLGSMKEENNH---LQEELERLRE 874 Query: 204 E-NRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRH 323 E +R + + + L E+ L + LEEE+ H Sbjct: 875 EQSRTAPVADPKTLDSVTELASEVSQLNTIKEHLEEEIKHH 915 Score = 32.0 bits (71), Expect = 0.67 Identities = 29/116 (25%), Positives = 57/116 (49%), Gaps = 6/116 (5%) Frame = +3 Query: 6 LSVSIQEEQLKSMQAEMARLSLEKQLAQVQEK-LRLLSLEKHGE-----TSKCKDVEASK 167 L +S+ +EQ+K +A L + + Q +EK + LEK + +++E Sbjct: 1657 LQLSVSQEQVKQYALSLANLQMVLEHFQQEEKAMYSAELEKQKQLIAEWKKNAENLEGKV 1716 Query: 168 LMLQKELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEK 335 + LQ E + E N LD + + + ++ +++I LK Q +L +E+ V++K Sbjct: 1717 ISLQ---ECLDEANAALDSASRLTEQLDVK-EEQIEELKR-QNELRQEMLDDVQKK 1767
>MYSP_BLOTA (Q8MUF6) Paramyosin (Allergen Blo t 11)| Length = 875 Score = 35.0 bits (79), Expect = 0.079 Identities = 33/136 (24%), Positives = 65/136 (47%), Gaps = 5/136 (3%) Frame = +3 Query: 3 KLSVSIQE--EQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLML 176 K++ I E EQL+++ + + +LEKQ A++Q ++ +L ++ T+ + +E L Sbjct: 316 KMAQKISEYGEQLEALLNKCS--ALEKQKARLQSEVEVLIMDLEKATAHAQALEKRVSQL 373 Query: 177 QK---ELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQ 347 +K +L+ EE L +Q V I ++ L++ KL ++ E K L Sbjct: 374 EKINLDLKSKLEEVSMLLEQTQKDLRVKIA---DLQKLQHEYEKLRDQKEALARENKKLA 430 Query: 348 HELSHIXNDRGDVERK 395 +L+ + D R+ Sbjct: 431 DDLAEAKSQLNDAHRR 446 Score = 32.7 bits (73), Expect = 0.39 Identities = 25/117 (21%), Positives = 54/117 (46%), Gaps = 10/117 (8%) Frame = +3 Query: 81 LAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIREENRKLDDQNHSSTSVIIRL 260 L ++++K+RLLS + E + VE K + +L + E + + + S T + + Sbjct: 32 LTRLEDKIRLLSEDLESERELRQRVEREKSDITVQLMNLTERLEETEGSSESVTEMNKKR 91 Query: 261 QDEIISLKNAQRKL---EEEVSRHVEEK-----KALQHELSHI--XNDRGDVERKHF 401 E+ L+ + EE + H+ +K + +Q +L + ++ D E++ F Sbjct: 92 DSELAKLRKLLEDVHMESEETAHHLRQKHQAAIQEMQDQLDQVQKAKNKSDKEKQKF 148
>GOGA4_MOUSE (Q91VW5) Golgin subfamily A member 4 (tGolgin-1)| Length = 2238 Score = 35.0 bits (79), Expect = 0.079 Identities = 31/145 (21%), Positives = 70/145 (48%), Gaps = 12/145 (8%) Frame = +3 Query: 30 QLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIREEN 209 QL+ + + +L +K + + K ++L ET + K+ E ++L + ++ + + Sbjct: 367 QLRDAKNLIEQLEQDKGMVITETKRQML------ETLELKEDEIAQL--RSHIKQMTTQG 418 Query: 210 RKLDDQNHSSTSVIIRLQDEIISL----KNAQRKLEEEVSRHV--------EEKKALQHE 353 +L +Q S ++ +S ++AQR+++ E+ + EE+ LQHE Sbjct: 419 EELREQKEKSERAAFEELEKALSTAQKTEDAQRRMKMEMDEQMKAVERASEEERLRLQHE 478 Query: 354 LSHIXNDRGDVERKHFSIKEQIQAV 428 LS + + + +K + +EQ+ A+ Sbjct: 479 LSRVRQEAASMAKK--NSEEQVAAL 501 Score = 33.9 bits (76), Expect = 0.18 Identities = 30/118 (25%), Positives = 61/118 (51%), Gaps = 3/118 (2%) Frame = +3 Query: 72 EKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIREENRKLDDQN---HSST 242 E+QLAQ+Q+K+ L EK T + ++E K + +EL+ R + ++L+ Q Sbjct: 838 EEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKV 897 Query: 243 SVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHIXNDRGDVERKHFSIKEQ 416 + +LQD LKN+ + +E+ + + EK+ + ++ ++ ++ S KE+ Sbjct: 898 RSLAQLQDS--QLKNSTVE-KEQARQSLMEKENIILQMREEQAKEIEILKQTLSSKEE 952 Score = 30.8 bits (68), Expect = 1.5 Identities = 27/117 (23%), Positives = 58/117 (49%), Gaps = 10/117 (8%) Frame = +3 Query: 18 IQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHG--------ETSKCKDVEASKLM 173 + E+L S + E++R LE + ++QE++R+ +LEK E + + + +L Sbjct: 504 LHAEELASKEQELSR-RLEARERELQEQMRI-ALEKSRSEYLKLTQEKEQQESLALEELE 561 Query: 174 LQKELEMIREENR--KLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKK 338 LQK+ + EN+ +L + + + I+ L+ + + E ++ H+E +K Sbjct: 562 LQKKAILTESENKLQELGQEAEAYRTRILELETSLEKSLQESKTQSEHLAVHLEAEK 618 Score = 28.9 bits (63), Expect = 5.7 Identities = 32/138 (23%), Positives = 62/138 (44%), Gaps = 5/138 (3%) Frame = +3 Query: 21 QEEQLKSMQAEMARLSLEKQ-LAQVQEKLRLLSLEKHGETSKCKDVEASKL----MLQKE 185 +E+Q+K+M+A++ L EK+ L Q + R + EK ++ K A + +L++E Sbjct: 1317 KEKQIKTMKADIEGLLTEKEALQQEGGQQRQAASEKESCITQLKKELAENINAVTLLREE 1376 Query: 186 LEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHI 365 L + E L Q S + + IS + + +H E++ LQ +L + Sbjct: 1377 LSEKKSEIASLSKQ----LSDLGAQLESSISPSDKAEAISALSKQHEEQELQLQAQLQEL 1432 Query: 366 XNDRGDVERKHFSIKEQI 419 + ++ S EQ+ Sbjct: 1433 SLKVDALSKEKMSALEQV 1450 Score = 28.5 bits (62), Expect = 7.4 Identities = 23/83 (27%), Positives = 36/83 (43%) Frame = +3 Query: 72 EKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIREENRKLDDQNHSSTSVI 251 E++L Q QE L L KH T K E + + QKE E+ R +D ++ Sbjct: 1987 EEKLKQEQEDLEL----KHTSTLKQLMREFNTQLAQKEQELERTVQETIDKAQEVEAELL 2042 Query: 252 IRLQDEIISLKNAQRKLEEEVSR 320 Q+E L + E+++ R Sbjct: 2043 ESHQEETQQLHRKIAEKEDDLRR 2065
>BPA1_HUMAN (Q03001) Bullous pemphigoid antigen 1 isoforms 1/2/3/4/5/8 (230 kDa| bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin) (Fragment) Length = 3214 Score = 35.0 bits (79), Expect = 0.079 Identities = 28/136 (20%), Positives = 60/136 (44%) Frame = +3 Query: 24 EEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIRE 203 E+ ++ + E+ L LEK ++ + +L L++ T +C +E + + + + Sbjct: 1944 EQDMRELTYELNALQLEKTSSEEKARLLKDKLDETNNTLRCLKLELERK--DQAEKGYSQ 2001 Query: 204 ENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHIXNDRGD 383 + R+L Q + +T E LK +R + E+ ++L HE + + Sbjct: 2002 QLRELGRQLNQTTGKAEEAMQEASDLKKIKRNYQLEL-------ESLNHEKGKLQREVDR 2054 Query: 384 VERKHFSIKEQIQAVN 431 + R H ++ IQ +N Sbjct: 2055 ITRAHAVAEKNIQHLN 2070 Score = 33.5 bits (75), Expect = 0.23 Identities = 24/122 (19%), Positives = 56/122 (45%), Gaps = 4/122 (3%) Frame = +3 Query: 3 KLSVSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQK 182 K S +E + K + +++ E ++ ++ L E K E + L++ Sbjct: 2311 KFKQSAEEFRKKMEKLMESKVITENDISGIRLDFVSLQQENSRAQENAKLCETNIKELER 2370 Query: 183 ELEMIREENRKLDDQNHSSTSVIIRLQDEIISLK----NAQRKLEEEVSRHVEEKKALQH 350 +L+ RE+ ++ + +L+DE+I+ K N ++K+++++ H + LQ Sbjct: 2371 QLQQYREQMQQGQHMEANHYQKCQKLEDELIAQKREVENLKQKMDQQIKEHEHQLVLLQC 2430 Query: 351 EL 356 E+ Sbjct: 2431 EI 2432
>TPM_BRABE (Q9NDS0) Tropomyosin| Length = 284 Score = 35.0 bits (79), Expect = 0.079 Identities = 21/92 (22%), Positives = 40/92 (43%) Frame = +3 Query: 153 VEASKLMLQKELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEE 332 ++ LML+ + E + + + + ++L+DEI L R +E+E+ + E Sbjct: 4 IKKKMLMLKNDKENALDRAEQAEQAMKDAQEKNVKLEDEINDLNKKIRMVEDELDKAQES 63 Query: 333 KKALQHELSHIXNDRGDVERKHFSIKEQIQAV 428 K +L D E + S+ +IQ V Sbjct: 64 LKEATEQLEAATKKAADAEAEVASLNRRIQLV 95
>HMMR_RAT (P97779) Hyaluronan-mediated motility receptor (Intracellular| hyaluronic acid-binding protein) (Receptor for hyaluronan-mediated motility) Length = 498 Score = 35.0 bits (79), Expect = 0.079 Identities = 32/143 (22%), Positives = 65/143 (45%), Gaps = 12/143 (8%) Frame = +3 Query: 3 KLSVSIQEEQLKSMQAEMA--------RLSLEKQLAQVQEKLRLLSLEKHGETSKCKD-- 152 KL ++ EE LK E+ ++S KQ+ + K +LL E+ SK ++ Sbjct: 37 KLDIAQLEEDLKEKDREILCLKQSLEEKVSFSKQIEDLTVKCQLLEAERDDLVSKDRERA 96 Query: 153 --VEASKLMLQKELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHV 326 + A +L ++L + R+E KL S S++ + ++ L+ +EE++ Sbjct: 97 ESLSAEMQVLTEKLLLERQEYEKLQQNELQSQSLLQQEKELSAHLQQQLCSFQEEMT--- 153 Query: 327 EEKKALQHELSHIXNDRGDVERK 395 E+ + +L ++ V++K Sbjct: 154 SERNVFKEQLKLALDELDAVQQK 176
>EZRI_RABIT (Q8HZQ5) Ezrin (p81) (Cytovillin) (Villin-2)| Length = 585 Score = 35.0 bits (79), Expect = 0.079 Identities = 24/113 (21%), Positives = 55/113 (48%) Frame = +3 Query: 21 QEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIR 200 +E+ K ++ + +++ A QEK ++L EK + +D E +KEL Sbjct: 310 EEKHQKQLERQQLESEKKRREAVEQEKEQMLR-EKEELMMRLQDYEQKTKKAEKELSDQI 368 Query: 201 EENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELS 359 + +L+D+ + RL+ + ++ A+ +LE + + ++ ++ L EL+ Sbjct: 369 QRALQLEDERKRAQEESERLEADRVAALRAKEELERQAADQIKSQEQLAAELA 421
>ATG11_ASHGO (Q75B79) Autophagy-related protein 11| Length = 1072 Score = 35.0 bits (79), Expect = 0.079 Identities = 28/125 (22%), Positives = 60/125 (48%), Gaps = 7/125 (5%) Frame = +3 Query: 81 LAQVQEKLRLLSLEKHGET----SKCKDVEASKLMLQKELEMIREENRKLDDQNHSSTSV 248 +A + EKL L + S K++++ + LQK+LE + E +++ Q ++ + Sbjct: 597 IASINEKLLLSDYKSRDSIMSGKSNEKELQSQLVELQKQLEEAKNEAKRVQQQLKTTKTQ 656 Query: 249 IIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHIXND---RGDVERKHFSIKEQI 419 ++ +DE + K L E+S+ + ++ + EL D + DV + + + + Sbjct: 657 LLNGEDERTAYKETLSILNAELSKLILNQEEQKQELVIAAKDFQEKLDVSMR--QVNDLL 714 Query: 420 QAVNF 434 + VNF Sbjct: 715 KQVNF 719
>MRIP_HUMAN (Q6WCQ1) Myosin phosphatase Rho-interacting protein (Rho-interacting| protein 3) (M-RIP) (RIP3) (p116Rip) Length = 1024 Score = 35.0 bits (79), Expect = 0.079 Identities = 40/154 (25%), Positives = 70/154 (45%), Gaps = 16/154 (10%) Frame = +3 Query: 15 SIQEEQLKSMQAEMARLSLEKQLAQVQEKLRL----LSLEKHGETSKC------------ 146 S+ E++L+ Q E + L + +L Q Q ++ L + E + + C Sbjct: 676 SLLEKELEQSQKEASDLLEQNRLLQDQLRVALGREQSAREGYVLQATCERGFAAMEETHQ 735 Query: 147 KDVEASKLMLQKELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHV 326 K +E + Q+ELE +REE +L + ++T I ++KNA R EE+ R + Sbjct: 736 KKIEDLQRQHQRELEKLREEKDRLLAEETAATISAIE------AMKNAHR---EEMEREL 786 Query: 327 EEKKALQHELSHIXNDRGDVERKHFSIKEQIQAV 428 E+ + S I + DVE E++Q+V Sbjct: 787 EKS-----QRSQISSVNSDVEALRRQYLEELQSV 815
>GOGA4_HUMAN (Q13439) Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa| golgin) (Golgin-245) (Protein 72.1) Length = 2230 Score = 35.0 bits (79), Expect = 0.079 Identities = 29/115 (25%), Positives = 54/115 (46%) Frame = +3 Query: 72 EKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIREENRKLDDQNHSSTSVI 251 E+QLAQ+Q+KL L E+ T + +VEA K + EL+ + + + L Q S Sbjct: 818 EEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNS-- 875 Query: 252 IRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHIXNDRGDVERKHFSIKEQ 416 ++ ++ SL E+ ++ E+ K + E ++ + ++K I Q Sbjct: 876 -EMEQKVKSLTQVYESKLEDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQ 929 Score = 32.7 bits (73), Expect = 0.39 Identities = 32/130 (24%), Positives = 63/130 (48%), Gaps = 12/130 (9%) Frame = +3 Query: 66 SLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIREENRKLDDQNHSSTS 245 +L +QL Q + + + + ET + K+ E ++L + ++ + + +L +Q S Sbjct: 353 NLIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQL--RSRIKQMTTQGEELREQKEKSER 410 Query: 246 VIIRLQDEIISL----KNAQRKLEEEVSRHV--------EEKKALQHELSHIXNDRGDVE 389 ++ +S + A+RKL+ E+ + EE+ +LQ ELS + + DV Sbjct: 411 AAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVM 470 Query: 390 RKHFSIKEQI 419 +K S +EQI Sbjct: 471 KK--SSEEQI 478 Score = 32.3 bits (72), Expect = 0.51 Identities = 32/146 (21%), Positives = 65/146 (44%), Gaps = 13/146 (8%) Frame = +3 Query: 21 QEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHG--ETSKCKDVEASKLMLQKEL-- 188 +E Q+KSM+A++ L EK+ +L+K G + + E+ L+KEL Sbjct: 1302 KENQIKSMKADIESLVTEKE-----------ALQKEGGNQQQAASEKESCITQLKKELSE 1350 Query: 189 ---------EMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKA 341 E ++E+ ++ + T + ++LQ+ ISL + + ++ EEK Sbjct: 1351 NINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQNS-ISLSEKEAAISSLRKQYDEEKCE 1409 Query: 342 LQHELSHIXNDRGDVERKHFSIKEQI 419 L ++ + + ++ S EQ+ Sbjct: 1410 LLDQVQDLSFKVDTLSKEKISALEQV 1435 Score = 30.4 bits (67), Expect = 1.9 Identities = 30/143 (20%), Positives = 62/143 (43%), Gaps = 6/143 (4%) Frame = +3 Query: 6 LSVSIQEEQLKS------MQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASK 167 L S+QE + +S ++AE + + E + + K L SL+ + + ++ K Sbjct: 576 LEKSLQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLK 635 Query: 168 LMLQKELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQ 347 Q E+E +RE+ + + +I + ++ K E++ E ++L Sbjct: 636 QQYQTEMEKLREKCEQEKETLLKDKEIIFQAH-----IEEMNEKTLEKLDVKQTELESLS 690 Query: 348 HELSHIXNDRGDVERKHFSIKEQ 416 ELS + R +E + +K+Q Sbjct: 691 SELSEVLKARHKLEEELSVLKDQ 713 Score = 28.5 bits (62), Expect = 7.4 Identities = 21/108 (19%), Positives = 50/108 (46%), Gaps = 2/108 (1%) Frame = +3 Query: 21 QEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIR 200 ++EQ + + + ++Q+ EK + L+ E + + + +L LQK+ + Sbjct: 491 RKEQELTKKLQTREREFQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKKAILTE 550 Query: 201 EENRKLDDQNHSST--SVIIRLQDEIISLKNAQRKLEEEVSRHVEEKK 338 EN+ D Q + T + I+ L+ + + ++++ H+E +K Sbjct: 551 SENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAVHLEAEK 598 Score = 28.1 bits (61), Expect = 9.7 Identities = 23/90 (25%), Positives = 43/90 (47%) Frame = +3 Query: 66 SLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIREENRKLDDQNHSSTS 245 SL K+ Q+ ++LR + K ++ + MLQ+E + ++ L S Sbjct: 133 SLNKE--QLIQRLRRMERSLSSYRGKYSELVTAYQMLQREKKKLQGI---LSQSQDKSLR 187 Query: 246 VIIRLQDEIISLKNAQRKLEEEVSRHVEEK 335 I L++E+ + A++ L+EE +EEK Sbjct: 188 RIAELREELQMDQQAKKHLQEEFDASLEEK 217
>LRC45_MOUSE (Q8CIM1) Leucine-rich repeat-containing protein 45| Length = 670 Score = 35.0 bits (79), Expect = 0.079 Identities = 38/152 (25%), Positives = 72/152 (47%), Gaps = 18/152 (11%) Frame = +3 Query: 21 QEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKC---------KDVEASKLM 173 +EE +K+ ARL + +LA ++EK+RLL+ + C S+L Sbjct: 484 EEELIKARN--QARLEEQHRLAHLEEKIRLLAQARDEAQGTCVQQKQMVAESQARVSQLN 541 Query: 174 LQKE-----LEMIREENRKLDDQNHSSTS-VIIRLQDEIISLKN---AQRKLEEEVSRHV 326 LQ E LE +++E D + + + V + LQ+++ ++ AQ L E+V+ Sbjct: 542 LQMEGQQRRLEELQQELINKDQEKVAEVARVRVELQEQMGRMQADLVAQEALREKVAALE 601 Query: 327 EEKKALQHELSHIXNDRGDVERKHFSIKEQIQ 422 + K + E DR E ++ S++E+++ Sbjct: 602 RQMKVIGSEHREALLDR---ESENASLREKLR 630
>IFT74_MOUSE (Q8BKE9) Intraflagellar transport 74 homolog (Coiled-coil| domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1) Length = 600 Score = 35.0 bits (79), Expect = 0.079 Identities = 27/135 (20%), Positives = 62/135 (45%), Gaps = 5/135 (3%) Frame = +3 Query: 36 KSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKE--LEMIREEN 209 +S++ E+A ++++ + EKL LE H + +D M ++E L+ ++E+N Sbjct: 259 ESLETEIAHSQVKQEAVLLYEKL--YELESHRDQMIAEDKSMGSPMEERERLLKQVKEDN 316 Query: 210 RKLDDQNHSSTSV---IIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHIXNDRG 380 +++ T + I + +EI L + + E+++ +E K + + Sbjct: 317 QEIASMERQLTDIKEKINQFSEEIRQLDMDLEEHQGEMNQKYKELKKREENMDAFIETFE 376 Query: 381 DVERKHFSIKEQIQA 425 + + + K QI+A Sbjct: 377 ETKNQELERKAQIEA 391
>CP135_HUMAN (Q66GS9) Centrosomal protein of 135 kDa (Cep135 protein)| (Centrosomal protein 4) Length = 1140 Score = 35.0 bits (79), Expect = 0.079 Identities = 31/122 (25%), Positives = 57/122 (46%), Gaps = 14/122 (11%) Frame = +3 Query: 3 KLSVSIQE--EQLKSMQAEMARLSLEKQLAQVQEK--------LRLLSLEKHGETSKCKD 152 KLSV E E+L +++ E + + + + EK LR + EK K + Sbjct: 535 KLSVLYNEAQEELSALRKESTQTTAPHNIVSLMEKEKELALSDLRRIMAEKEALREKLEH 594 Query: 153 VEASKLMLQKELEMIREE----NRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSR 320 +E L + ELE E N +L+ + + S ++ +++ I SL+N + K++ + Sbjct: 595 IEEVSLFGKSELEKTIEHLTCVNHQLESEKYELKSKVLIMKETIESLEN-KLKVQAQKFS 653 Query: 321 HV 326 HV Sbjct: 654 HV 655 Score = 31.6 bits (70), Expect = 0.87 Identities = 28/138 (20%), Positives = 59/138 (42%), Gaps = 17/138 (12%) Frame = +3 Query: 3 KLSVSIQE-EQLKSM---------QAEMARLSLEKQLAQVQEKLRLL-------SLEKHG 131 +L ++QE E++KS + E + EK+ + ++ ++L ++ H Sbjct: 840 ELEAAVQEKEEMKSRVHKYITEVSRWESLMAAKEKENQDLLDRFQMLHNRAEDWEVKAHQ 899 Query: 132 ETSKCKDVEASKLMLQKELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEE 311 + V L + E +RE L+ + + + +I S+ A +LEEE Sbjct: 900 AEGESSSVRLELLSIDTERRHLRERVELLEKEIQEHINAHHAYESQISSMAKAMSRLEEE 959 Query: 312 VSRHVEEKKALQHELSHI 365 + +EK + ++LS + Sbjct: 960 LRHQEDEKATVLNDLSSL 977 Score = 28.1 bits (61), Expect = 9.7 Identities = 28/140 (20%), Positives = 61/140 (43%), Gaps = 26/140 (18%) Frame = +3 Query: 6 LSVSIQEEQLKSMQAEMARLSLEKQLAQ--VQEKLRLLSLEKHGETSKCKDVEASKLMLQ 179 L ++ Q+E+ M+ + + EK Q V EK ++ + +K K V K+M+ Sbjct: 713 LKMTSQDEEAHVMKKTIGVIDKEKDFLQETVDEKTEKIANLQENLANKEKAVAQMKIMIS 772 Query: 180 -----------------KELEMIREE----NRKLDDQNHSSTSVII---RLQDEIISLKN 287 +E+ +R + +++LD+ S RLQD++ ++ Sbjct: 773 ECESSVNQLKETLVNRDREINSLRRQLDAAHKELDEVGRSREIAFKENRRLQDDLATMAR 832 Query: 288 AQRKLEEEVSRHVEEKKALQ 347 +++ E+ V+EK+ ++ Sbjct: 833 ENQEISLELEAAVQEKEEMK 852
>NUF1_YEAST (P32380) Protein NUF1 (Spindle poly body spacer protein SPC110)| Length = 944 Score = 35.0 bits (79), Expect = 0.079 Identities = 28/141 (19%), Positives = 68/141 (48%) Frame = +3 Query: 12 VSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELE 191 +S + QL + + ++A SL QL Q++ KL + S+ ++++ + LQK++ Sbjct: 369 ISTKNSQLIAKEGKLA--SLMAQLTQLESKLNQRDSQLG---SREEELKKTNDKLQKDIR 423 Query: 192 MIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHIXN 371 + REE D++ + +L++++ +K + + +E K L + + N Sbjct: 424 IAREETVSKDERIIDLQKKVKQLENDLFVIKKTHSESKTITDNELESKDKL---IKILEN 480 Query: 372 DRGDVERKHFSIKEQIQAVNF 434 D + K+ ++++++ F Sbjct: 481 DLKVAQEKYSKMEKELKEREF 501 Score = 35.0 bits (79), Expect = 0.079 Identities = 30/135 (22%), Positives = 64/135 (47%), Gaps = 5/135 (3%) Frame = +3 Query: 6 LSVSIQEEQLKSMQAEMARLSL-----EKQLAQVQEKLRLLSLEKHGETSKCKDVEASKL 170 L + +E++LK++ E+ L + QL + +LR + E + K +++ Sbjct: 262 LKLRSKEDELKNLMNELNELKSNAEEKDTQLEFKKNELRKRTNELNELKIKSDEMDLQLK 321 Query: 171 MLQKELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQH 350 Q E + +++E +L+ + + S ++E+ LKN +LEEE+S + A + Sbjct: 322 QKQNESKRLKDELNELETKFSENGSQSSAKENELKMLKNKIAELEEEISTKNSQLIAKEG 381 Query: 351 ELSHIXNDRGDVERK 395 +L+ + +E K Sbjct: 382 KLASLMAQLTQLESK 396 Score = 35.0 bits (79), Expect = 0.079 Identities = 30/139 (21%), Positives = 64/139 (46%), Gaps = 8/139 (5%) Frame = +3 Query: 27 EQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIREE 206 + LK + ++ E+ ++ KL L K T D+ +L + E++ ++ E Sbjct: 117 QPLKEQEVREHQMKKERFDRALESKL----LGKRHITYANSDISNKELYIN-EIKSLKHE 171 Query: 207 NRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEV--------SRHVEEKKALQHELSH 362 ++L + + + + L++E LKN + LE+E+ SR V++ E Sbjct: 172 IKELRKEKNDTLNNYDTLEEETDDLKNRLQALEKELDAKNKIVNSRKVDDHSGCIEEREQ 231 Query: 363 IXNDRGDVERKHFSIKEQI 419 + ++ERK ++K+Q+ Sbjct: 232 MERKLAELERKLKTVKDQV 250 Score = 31.2 bits (69), Expect = 1.1 Identities = 24/102 (23%), Positives = 53/102 (51%), Gaps = 6/102 (5%) Frame = +3 Query: 72 EKQLAQVQEKLRLLSLEKHGETSKCKD--VEASKLMLQKELEMIREENRK----LDDQNH 233 EKQL +++ +E++ E++K + +E K+ + + + E+ K D+Q Sbjct: 550 EKQLESLRK-----DIEEYKESAKDSEDKIEELKIRIAENSAKVSEKRSKDIKQKDEQIS 604 Query: 234 SSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELS 359 T + +DEI SLK+ + +++ ++ E+ +QH+L+ Sbjct: 605 DLTQNLKLQEDEISSLKSIIDRYKKDFNQLKSEQSNIQHDLN 646
>HOOK3_MOUSE (Q8BUK6) Hook homolog 3| Length = 718 Score = 35.0 bits (79), Expect = 0.079 Identities = 31/118 (26%), Positives = 57/118 (48%) Frame = +3 Query: 63 LSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIREENRKLDDQNHSST 242 L L+ QL Q+QE+ L K +C+++E KE+ +R++N +L + Sbjct: 245 LQLQTQLEQLQEETFRLEAAKDDYRIRCEELE-------KEISELRQQNDELTTLADEAQ 297 Query: 243 SVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHIXNDRGDVERKHFSIKEQ 416 S L+DEI L+++ K+ + + KK L+ D GD+ R+ ++E+ Sbjct: 298 S----LKDEIDVLRHSSDKVSKLEGQVESYKKKLE--------DLGDLRRQVKLLEEK 343
>HOOK3_HUMAN (Q86VS8) Hook homolog 3 (hHK3)| Length = 718 Score = 35.0 bits (79), Expect = 0.079 Identities = 31/118 (26%), Positives = 57/118 (48%) Frame = +3 Query: 63 LSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIREENRKLDDQNHSST 242 L L+ QL Q+QE+ L K +C+++E KE+ +R++N +L + Sbjct: 245 LQLQTQLEQLQEETFRLEAAKDDYRIRCEELE-------KEISELRQQNDELTTLADEAQ 297 Query: 243 SVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHIXNDRGDVERKHFSIKEQ 416 S L+DEI L+++ K+ + + KK L+ D GD+ R+ ++E+ Sbjct: 298 S----LKDEIDVLRHSSDKVSKLEGQVESYKKKLE--------DLGDLRRQVKLLEEK 343
>AL2S3_HUMAN (O60296) Amyotrophic lateral sclerosis 2 chromosomal region| candidate gene 3 protein (Trafficking protein, kinesin-binding 2) Length = 914 Score = 35.0 bits (79), Expect = 0.079 Identities = 26/104 (25%), Positives = 47/104 (45%), Gaps = 11/104 (10%) Frame = +3 Query: 78 QLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQ-----------KELEMIREENRKLDD 224 QL +QEKL+ L E SK ++ + + KEL + ++ + Sbjct: 209 QLEMLQEKLKELEEENMALRSKACHIKTETVTYEEKEQQLVSDCVKELRETNAQMSRMTE 268 Query: 225 QNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHEL 356 + + +IR Q+E+ SL + L+ ++ HV EK+ L+ L Sbjct: 269 ELSGKSDELIRYQEELSSLLSQIVDLQHKLKEHVIEKEELKLHL 312
>KTN1_VULVU (O97961) Kinectin| Length = 1330 Score = 35.0 bits (79), Expect = 0.079 Identities = 32/163 (19%), Positives = 78/163 (47%), Gaps = 22/163 (13%) Frame = +3 Query: 6 LSVSIQEEQLKSMQAEMARLSLEKQ-----------LAQVQEKLRLLSLEKHGETSKCKD 152 + V+ +EE+L +++ E + L+ E Q A + E+L+ + EK G+ ++ Sbjct: 756 IQVATKEEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEE 815 Query: 153 VEASKLM-----------LQKELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRK 299 + ++++ L++E+E ++EE + + S+ ++Q+ L+N + Sbjct: 816 LLEAEVLKVANKEKTIQDLKQEIEALKEEIGNIQLEKAQQLSITSQIQE----LQNLLKG 871 Query: 300 LEEEVSRHVEEKKALQHELSHIXNDRGDVERKHFSIKEQIQAV 428 EE+++ + + +L+ D++ ++ S+K IQ V Sbjct: 872 KEEQMNTMKTVLEEKEKDLASRGKWLQDLQEENESLKTHIQEV 914 Score = 29.3 bits (64), Expect = 4.3 Identities = 27/116 (23%), Positives = 55/116 (47%) Frame = +3 Query: 12 VSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELE 191 + ++ E+ KS+ AE + L+K V+++ ++ K ++ S ++ELE Sbjct: 1133 LQLECEKYKSVLAETEGI-LQKLQRSVEQEENKWKVKVDESQKTIKQMQLSFTSSEQELE 1191 Query: 192 MIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELS 359 +R EN+ +++ L+ E L+ K E E S +V E + L+ +L+ Sbjct: 1192 RLRRENKDIEN-----------LRREREHLEMELEKAEIERSTYVTEVRELKTQLN 1236
>AKAP9_RABIT (Q28628) A-kinase anchor protein 9 (Protein kinase A-anchoring| protein 9) (PRKA9) (A-kinase anchor protein 120 kDa) (AKAP 120) (Fragment) Length = 1087 Score = 34.7 bits (78), Expect = 0.10 Identities = 32/139 (23%), Positives = 57/139 (41%), Gaps = 2/139 (1%) Frame = +3 Query: 3 KLSVSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQK 182 K V I E+ + ++ L Q ++ +++ R HG+ + + + + Sbjct: 643 KEQVEIAEKNALEKEKKLQELQKLVQDSETKQRERERQSRLHGDLGVLESTTSEESGVFG 702 Query: 183 ELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSH 362 ELE +R E+ + E+ + K KL+EE+ +L ELSH Sbjct: 703 ELEALRAES--------------AAPKGELANYKELAEKLQEELLVKETNMASLPKELSH 748 Query: 363 IXNDRGDVERK--HFSIKE 413 + + + E K HFS KE Sbjct: 749 VRDQLTEAEDKLSHFSEKE 767
>PEPL_MOUSE (Q9R269) Periplakin| Length = 1755 Score = 34.7 bits (78), Expect = 0.10 Identities = 26/92 (28%), Positives = 39/92 (42%) Frame = +3 Query: 30 QLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIREEN 209 Q++ E L+K L + + R L E +K ++E KEL+ +REEN Sbjct: 1505 QVEKGDTEQEIQRLKKSLEEESQSKRELDSEVTRLEAKLSELEFYNSKSSKELDFLREEN 1564 Query: 210 RKLDDQNHSSTSVIIRLQDEIISLKNAQRKLE 305 KL + + RLQ EI R L+ Sbjct: 1565 HKLQLERQNLQLETRRLQSEIEMAATETRDLK 1596 Score = 34.3 bits (77), Expect = 0.13 Identities = 31/136 (22%), Positives = 67/136 (49%), Gaps = 1/136 (0%) Frame = +3 Query: 21 QEEQLKSMQAEMARLSLEKQLAQVQEKLR-LLSLEKHGETSKCKDVEASKLMLQKELEMI 197 QEE+L +QA++ RL E+ +A+ + ++ +L +EK + E + L Q E Sbjct: 1085 QEEELSFLQAKLRRLEKERAMAEGKITVKEVLKVEKDAAVER----EVNDLTRQYE---- 1136 Query: 198 REENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHIXNDR 377 +E K T ++ ++ + +NA+ ++E+V V + E++++ + Sbjct: 1137 -DEAAKARSGQREKTELLRKIW--ALEEENAKVVVQEKVREIVRPDPKAESEVANLRLEL 1193 Query: 378 GDVERKHFSIKEQIQA 425 + ERK +EQ+++ Sbjct: 1194 VEQERKFRGAEEQLKS 1209 Score = 29.6 bits (65), Expect = 3.3 Identities = 26/116 (22%), Positives = 50/116 (43%), Gaps = 12/116 (10%) Frame = +3 Query: 3 KLSVSIQEEQLKSMQAEMARLSLEKQLAQVQ-------EKLRLLSLEKHGETSKCKDVEA 161 +L S++EE + + LE +L++++ ++L L E H + ++++ Sbjct: 1517 RLKKSLEEESQSKRELDSEVTRLEAKLSELEFYNSKSSKELDFLREENHKLQLERQNLQL 1576 Query: 162 SKLMLQKELEMIREENRKLD-----DQNHSSTSVIIRLQDEIISLKNAQRKLEEEV 314 LQ E+EM E R L D S + L+ E+ LK + + E+ Sbjct: 1577 ETRRLQSEIEMAATETRDLKNITTIDSGTHLNSRLWSLEKELDDLKKMSKDKDLEI 1632 Score = 29.6 bits (65), Expect = 3.3 Identities = 36/145 (24%), Positives = 67/145 (46%), Gaps = 12/145 (8%) Frame = +3 Query: 24 EEQLKSMQAEMARLSLEKQLAQVQEKLR-LLSLEKHGETSKCKDVEASKLMLQKELEMIR 200 EEQLKS Q+E+ L +V+E + ++ ET ++EL+ +R Sbjct: 1204 EEQLKSYQSELEALRNRGPQVEVKEVTKEVIKYTTDPET-------------EQELQRLR 1250 Query: 201 EENRKLDDQNHSSTSVIIRLQDEIISLKNAQ-----RKLEEEVSRHVE------EKKALQ 347 EE I +L+ EI +LK+ + R++ +E+ + E E ++L+ Sbjct: 1251 EEIMDKTRLIERCDLEIYQLKQEIQALKDTKPQVQTREVVQEILQFQEDPQTKKEVESLR 1310 Query: 348 HELSHIXNDRGDVERKHFSIKEQIQ 422 +LS + D+E + S +E+I+ Sbjct: 1311 IQLSEEQKKQVDLEGERASQEEKIK 1335
>ITSN2_HUMAN (Q9NZM3) Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18)| (SH3P18-like WASP-associated protein) Length = 1696 Score = 34.7 bits (78), Expect = 0.10 Identities = 40/143 (27%), Positives = 60/143 (41%), Gaps = 7/143 (4%) Frame = +3 Query: 21 QEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIR 200 Q E + Q E +++ Q QE + L LEK +L Q+ELE R Sbjct: 389 QREAERKAQKEKEEWERKQRELQEQEWKKQLELEK-------------RLEKQRELERQR 435 Query: 201 EENRKLDDQNHSSTSVII----RLQDEII---SLKNAQRKLEEEVSRHVEEKKALQHELS 359 EE R+ D + + + RL+ E I L N + + +EE+ R +KK L EL Sbjct: 436 EEERRKDIERREAAKQELERQRRLEWERIRRQELLNQKNREQEEIVRLNSKKKNLHLELE 495 Query: 360 HIXNDRGDVERKHFSIKEQIQAV 428 + KH I ++Q V Sbjct: 496 ALNG-------KHQQISGRLQDV 511
>GOGA5_MOUSE (Q9QYE6) Golgin subfamily A member 5 (Golgin-84) (Sumiko protein)| (Ret-II protein) Length = 729 Score = 34.7 bits (78), Expect = 0.10 Identities = 27/101 (26%), Positives = 48/101 (47%) Frame = +3 Query: 18 IQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMI 197 ++ SM+ E R E Q ++Q+ L + H S+ +D+EA ++ E E Sbjct: 456 LESSTASSMELEELRHEKEMQKEEIQK----LMGQMHQLRSELQDMEAQQV---SEAESA 508 Query: 198 REENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSR 320 RE+ + L DQ + L+ E+ +K R +EE++ R Sbjct: 509 REQLQDLQDQIAKQRTSKQELETELERMKQEFRYMEEDLHR 549
>EP15_MOUSE (P42567) Epidermal growth factor receptor substrate 15 (Protein| Eps15) (AF-1p protein) Length = 897 Score = 34.7 bits (78), Expect = 0.10 Identities = 31/139 (22%), Positives = 58/139 (41%) Frame = +3 Query: 6 LSVSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKE 185 L+ I + Q + E E + Q +++ L E E+ + ++A K +Q+ Sbjct: 338 LNNEIVDLQREKNNVEQDLKEKEDTVKQRTSEVQDLQDEVQRESINLQKLQAQKQQVQEL 397 Query: 186 LEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHI 365 L + E+ +L++Q I SLK E ++S + EE + ELS + Sbjct: 398 LGELDEQKAQLEEQLQEVRKKCAEEAQLISSLKAEITSQESQISSYEEELLKAREELSRL 457 Query: 366 XNDRGDVERKHFSIKEQIQ 422 + +E S K Q++ Sbjct: 458 QQETAQLEESVESGKAQLE 476 Score = 29.3 bits (64), Expect = 4.3 Identities = 26/120 (21%), Positives = 56/120 (46%), Gaps = 3/120 (2%) Frame = +3 Query: 9 SVSIQEEQLKSMQAEMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKEL 188 S+++Q+ Q + Q + L++Q AQ++E+L+ + + E ++A + ++ Sbjct: 381 SINLQKLQAQKQQVQELLGELDEQKAQLEEQLQEVRKKCAEEAQLISSLKAEITSQESQI 440 Query: 189 EMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLE---EEVSRHVEEKKALQHELS 359 EE K ++ + RLQ E L+ + + E + +H++E Q E+S Sbjct: 441 SSYEEELLKAREE-------LSRLQQETAQLEESVESGKAQLEPLQQHLQES---QQEIS 490
>TPM1_XENLA (Q01173) Tropomyosin 1 alpha chain (Alpha-tropomyosin)| Length = 284 Score = 34.7 bits (78), Expect = 0.10 Identities = 24/87 (27%), Positives = 41/87 (47%) Frame = +3 Query: 168 LMLQKELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQ 347 L L KE + R E + D + S +L+DE+++L+ + E+E+ ++ E K Q Sbjct: 11 LKLDKENALDRAEQAEADKKGAEDKSK--QLEDELVALQKKLKGTEDELDKYSEALKDAQ 68 Query: 348 HELSHIXNDRGDVERKHFSIKEQIQAV 428 +L D E S+ +IQ V Sbjct: 69 EKLELSDKKATDAEGDVASLNRRIQLV 95 Score = 33.5 bits (75), Expect = 0.23 Identities = 27/108 (25%), Positives = 51/108 (47%) Frame = +3 Query: 51 EMARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMIREENRKLDDQN 230 E A LS E + A+++E+L+ + T+ K +EA ++ + EE + L D+ Sbjct: 181 ERAELS-ESKCAELEEELKTV-------TNNLKSLEAQAEKYSQKEDKYEEEIKVLTDKL 232 Query: 231 HSSTSVIIRLQDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHIXND 374 + + + + L+ + LE+E+ + KA+ EL H ND Sbjct: 233 KEAETRAEFAERTVAKLEKSIDDLEDELYAQKLKYKAISEELDHALND 280
>SMC2_XENLA (P50533) Structural maintenance of chromosome 2| (Chromosome-associated protein E) (Chromosome assembly protein XCAP-E) Length = 1203 Score = 34.7 bits (78), Expect = 0.10 Identities = 31/148 (20%), Positives = 62/148 (41%), Gaps = 16/148 (10%) Frame = +3 Query: 24 EEQLKSMQAEM--ARLSLEKQLAQVQEKLRLLSLEKHGETSKCKDVEASKLMLQKELEMI 197 EE+ K ++ +M A E++L + Q+KL + K K+ + L ELE + Sbjct: 771 EEKFKVLEHKMKNAEAERERELKEAQQKLDTAKKKADASNKKMKEKQQEVDALVLELEEL 830 Query: 198 REENRKLDDQNHSSTSVIIRLQDEIISL-------KNAQRKLEEEVSR-------HVEEK 335 + E Q + + Q++ S+ K A +K ++E+++ H +E Sbjct: 831 KREQTTYKQQIETVDEAMKAYQEQADSMASEVSKNKEAVKKAQDELAKQKEIIMGHDKEI 890 Query: 336 KALQHELSHIXNDRGDVERKHFSIKEQI 419 K E + + D++ K ++ I Sbjct: 891 KTKSSEAGKLRENNNDLQLKIKELEHNI 918
>HAP1_HUMAN (P54257) Huntingtin-associated protein 1 (HAP-1) (Neuroan 1)| Length = 671 Score = 34.7 bits (78), Expect = 0.10 Identities = 32/124 (25%), Positives = 56/124 (45%), Gaps = 9/124 (7%) Frame = +3 Query: 78 QLAQVQEKLRLLSLEKH---GETSKCKDVEASKLMLQKELEMIREENRKLDDQNHSSTSV 248 QL +QEKLRLL E H E S+ +E + ML LE + + + S + Sbjct: 313 QLEALQEKLRLLEEENHQLREEASQLDTLEDEEQML--ILECVEQFSEASQQMAELSEVL 370 Query: 249 IIRL------QDEIISLKNAQRKLEEEVSRHVEEKKALQHELSHIXNDRGDVERKHFSIK 410 ++RL Q E+ L+ KL++ + E + LQ +L+ + ++ + + Sbjct: 371 VLRLENYERQQQEVARLQAQVLKLQQRCRMYGAETEKLQKQLASEKEIQMQLQEESVWVG 430 Query: 411 EQIQ 422 Q+Q Sbjct: 431 SQLQ 434
>MRIP_MOUSE (P97434) Myosin phosphatase Rho-interacting protein (Rho-interacting| protein 3) (p116Rip) (RIP3) Length = 1024 Score = 34.7 bits (78), Expect = 0.10 Identities = 38/152 (25%), Positives = 72/152 (47%), Gaps = 16/152 (10%) Frame = +3 Query: 15 SIQEEQLKSMQAEMARLSLEKQLAQVQEKLRL----LSLEKHGETSKC------------ 146 S+ E++L+ Q E + L + +L Q Q ++ L + E + + C Sbjct: 676 SLLEKELEQSQKEASDLLEQNRLLQDQLRVALGREQSAREGYVLQATCERGFAAMEETHQ 735 Query: 147 KDVEASKLMLQKELEMIREENRKLDDQNHSSTSVIIRLQDEIISLKNAQRKLEEEVSRHV 326 K +E + Q+ELE +REE +L + ++T I ++KNA R EE+ R + Sbjct: 736 KKIEDLQRQHQRELEKLREEKDRLLAEETAATISAIE------AMKNAHR---EEMEREL 786 Query: 327 EEKKALQHELSHIXNDRGDVERKHFSIKEQIQ 422 E K+ + ++S I +D + R++ + +Q Sbjct: 787 E--KSQRSQISSINSDIEALRRQYLEELQSVQ 816 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 52,100,387 Number of Sequences: 219361 Number of extensions: 934190 Number of successful extensions: 6024 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 4908 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 5867 length of database: 80,573,946 effective HSP length: 101 effective length of database: 58,418,485 effective search space used: 2511994855 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)