Clone Name | bastl19a04 |
---|---|
Clone Library Name | barley_pub |
>YY46_ANASP (Q8YRI1) Hypothetical WD-repeat protein alr3466| Length = 1526 Score = 60.5 bits (145), Expect = 3e-09 Identities = 39/118 (33%), Positives = 63/118 (53%), Gaps = 2/118 (1%) Frame = +1 Query: 151 GHEDDVRGICICGDVGV-ATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAP 327 GH + V + D + A+ S D+TVR W+ K TL GH+++VG +V++P Sbjct: 1366 GHTNWVGSVIFSPDGAILASGSGDQTVRLWSISSGK-----CLYTLQGHNNWVGSIVFSP 1420 Query: 328 PSDRFPEGAIVSGGMDTQ-VLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSSMD 498 +G +++ G D Q V LWN+ +GE T+ GH + V +A +G I++S D Sbjct: 1421 ------DGTLLASGSDDQTVRLWNISSGECLYTLHGHINSVRSVAFSSDGLILASGSD 1472 Score = 53.9 bits (128), Expect = 2e-07 Identities = 35/116 (30%), Positives = 57/116 (49%), Gaps = 1/116 (0%) Frame = +1 Query: 145 LHGHEDDVRGICICGD-VGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVW 321 L GH + V + D +A+ S D+TVR W K Y+L GH+S+V +V+ Sbjct: 1154 LQGHTNWVNAVAFSPDGATLASGSGDQTVRLW-DISSSKCLYILQ----GHTSWVNSVVF 1208 Query: 322 APPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISS 489 P + SG D V LW +++ + T +GHTS V + + +G +++S Sbjct: 1209 NPDGS-----TLASGSSDQTVRLWEINSSKCLCTFQGHTSWVNSVVFNPDGSMLAS 1259 Score = 50.8 bits (120), Expect = 2e-06 Identities = 38/110 (34%), Positives = 55/110 (50%), Gaps = 2/110 (1%) Frame = +1 Query: 151 GHEDDVRGICICGDVGV-ATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAP 327 GH VR + D + A+ S D+TVR W TL GH+S V +V++P Sbjct: 1030 GHTSCVRSVVFSSDGAMLASGSDDQTVRLWDISSGN-----CLYTLQGHTSCVRSVVFSP 1084 Query: 328 PSDRFPEGAIV-SGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNG 474 +GA++ SGG D V LW++ +G T++G+TS V L NG Sbjct: 1085 ------DGAMLASGGDDQIVRLWDISSGNCLYTLQGYTSWVRFLVFSPNG 1128 Score = 50.4 bits (119), Expect = 3e-06 Identities = 35/115 (30%), Positives = 57/115 (49%), Gaps = 2/115 (1%) Frame = +1 Query: 151 GHEDDVRGICICGDVGV-ATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAP 327 GH + V + D + A+ S D+TVR W K T GH+S+V + ++P Sbjct: 1282 GHTNWVNSVAFNPDGSMLASGSGDQTVRLWEISSSK-----CLHTFQGHTSWVSSVTFSP 1336 Query: 328 PSDRFPEGAIVSGGMDTQ-VLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISS 489 +G +++ G D Q V LW++ +GE T GHT+ V + +G I++S Sbjct: 1337 ------DGTMLASGSDDQTVRLWSISSGECLYTFLGHTNWVGSVIFSPDGAILAS 1385 Score = 49.7 bits (117), Expect = 4e-06 Identities = 33/117 (28%), Positives = 52/117 (44%), Gaps = 1/117 (0%) Frame = +1 Query: 151 GHEDDVRGICICGDVGV-ATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAP 327 GH V + D + A+ S DKTVR W K T GH+++V + + P Sbjct: 1240 GHTSWVNSVVFNPDGSMLASGSSDKTVRLWDISSSK-----CLHTFQGHTNWVNSVAFNP 1294 Query: 328 PSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSSMD 498 + SG D V LW + + + T +GHTS V+ + +G +++S D Sbjct: 1295 DGSM-----LASGSGDQTVRLWEISSSKCLHTFQGHTSWVSSVTFSPDGTMLASGSD 1346 Score = 47.4 bits (111), Expect = 2e-05 Identities = 32/101 (31%), Positives = 54/101 (53%), Gaps = 1/101 (0%) Frame = +1 Query: 199 VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDT 378 +AT S D+TVR W + Y+ GH+S V +V++ +GA+++ G D Sbjct: 1005 LATGSGDQTVRLW-DISSSQCFYIFQ----GHTSCVRSVVFSS------DGAMLASGSDD 1053 Query: 379 Q-VLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSSMD 498 Q V LW++ +G T++GHTS V + +G +++S D Sbjct: 1054 QTVRLWDISSGNCLYTLQGHTSCVRSVVFSPDGAMLASGGD 1094 Score = 46.2 bits (108), Expect = 5e-05 Identities = 30/97 (30%), Positives = 50/97 (51%) Frame = +1 Query: 199 VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDT 378 +A+ S D+TVR W + KT GH+S V +V++P S + SG D Sbjct: 921 LASGSDDQTVRLWDISSGQ-----CLKTFKGHTSRVRSVVFSPNSLM-----LASGSSDQ 970 Query: 379 QVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISS 489 V LW++ +GE +GHT V +A + +G ++++ Sbjct: 971 TVRLWDISSGECLYIFQGHTGWVYSVAFNLDGSMLAT 1007 Score = 43.1 bits (100), Expect = 4e-04 Identities = 29/97 (29%), Positives = 48/97 (49%), Gaps = 1/97 (1%) Frame = +1 Query: 202 ATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDTQ 381 AT VRFW K+ T GH+S+V + ++ +G +++ G D Q Sbjct: 880 ATGDSGGIVRFWEAATGKEL-----LTCKGHNSWVNSVGFSQ------DGKMLASGSDDQ 928 Query: 382 -VLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISS 489 V LW++ +G+ T KGHTS+V + N +++S Sbjct: 929 TVRLWDISSGQCLKTFKGHTSRVRSVVFSPNSLMLAS 965 Score = 41.6 bits (96), Expect = 0.001 Identities = 31/116 (26%), Positives = 54/116 (46%), Gaps = 1/116 (0%) Frame = +1 Query: 145 LHGHEDDVRGICICGDVGV-ATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVW 321 L GH VR + D + A+ D+ VR W TL G++S+V +V+ Sbjct: 1070 LQGHTSCVRSVVFSPDGAMLASGGDDQIVRLWDISSGN-----CLYTLQGYTSWVRFLVF 1124 Query: 322 APPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISS 489 +P + +G D V LW++ + + T++GHT+ V +A +G ++S Sbjct: 1125 SPNGV-----TLANGSSDQIVRLWDISSKKCLYTLQGHTNWVNAVAFSPDGATLAS 1175 Score = 34.7 bits (78), Expect = 0.15 Identities = 29/97 (29%), Positives = 46/97 (47%), Gaps = 2/97 (2%) Frame = +1 Query: 145 LHGHEDDVRGICICGD-VGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVW 321 L GH + V I D +A+ S D+TVR W + TL GH + V + + Sbjct: 1406 LQGHNNWVGSIVFSPDGTLLASGSDDQTVRLWNISSGE-----CLYTLHGHINSVRSVAF 1460 Query: 322 APPSDRFPEGAIVSGGMDTQVL-LWNLHTGEVAGTMK 429 + +G I++ G D + + LW++ TGE T+K Sbjct: 1461 SS------DGLILASGSDDETIKLWDVKTGECIKTLK 1491 Score = 30.8 bits (68), Expect = 2.1 Identities = 19/62 (30%), Positives = 29/62 (46%) Frame = +1 Query: 313 MVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSS 492 + ++P F G SGG+ V W TG+ T KGH S V + +G +++S Sbjct: 870 VAFSPDGKLFATGD--SGGI---VRFWEAATGKELLTCKGHNSWVNSVGFSQDGKMLASG 924 Query: 493 MD 498 D Sbjct: 925 SD 926
>SEL10_CAEEL (Q93794) F-box/WD-repeat protein sel-10 (Suppressor/enhancer of| lin-12) (Sel-10 protein) Length = 587 Score = 58.2 bits (139), Expect = 1e-08 Identities = 41/119 (34%), Positives = 57/119 (47%), Gaps = 1/119 (0%) Frame = +1 Query: 145 LHGHEDDVRGICICGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWA 324 L GH VR + + G + + T SRD T+R W E R TL GH + V + Sbjct: 334 LQGHTSTVRCMAMAGSI-LVTGSRDTTLRVWDV--ESGRHLA---TLHGHHAAVRCV--- 384 Query: 325 PPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDII-SSSMD 498 +F +VSGG D V +WN HTG T+ GH ++V L + I+ S S+D Sbjct: 385 ----QFDGTTVVSGGYDFTVKIWNAHTGRCIRTLTGHNNRVYSLLFESERSIVCSGSLD 439 Score = 46.2 bits (108), Expect = 5e-05 Identities = 36/109 (33%), Positives = 50/109 (45%) Frame = +1 Query: 136 SAQLHGHEDDVRGICICGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPM 315 SA L GHED V D + T S D T++ W + + TLVGH+ V Sbjct: 248 SAVLRGHEDHVITCMQIHDDVLVTGSDDNTLKVWCIDKGE-----VMYTLVGHTGGV--- 299 Query: 316 VWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAI 462 W + IVSG D V +W+ G + T++GHTS V +A+ Sbjct: 300 -WTSQISQCGR-YIVSGSTDRTVKVWSTVDGSLLHTLQGHTSTVRCMAM 346 Score = 38.9 bits (89), Expect = 0.008 Identities = 31/119 (26%), Positives = 50/119 (42%), Gaps = 1/119 (0%) Frame = +1 Query: 145 LHGHEDDVRGICICGDVGVATS-SRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVW 321 L GH + V + + + S S D ++R W + +E V L GH+S M Sbjct: 414 LTGHNNRVYSLLFESERSIVCSGSLDTSIRVWDFTRPEGQECVA--LLQGHTSLTSGM-- 469 Query: 322 APPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSSMD 498 + +VS D+ V +W++H G + GH S +T L + +SS D Sbjct: 470 -----QLRGNILVSCNADSHVRVWDIHEGTCVHMLSGHRSAITSLQWFGRNMVATSSDD 523 Score = 31.6 bits (70), Expect = 1.2 Identities = 27/95 (28%), Positives = 40/95 (42%), Gaps = 1/95 (1%) Frame = +1 Query: 217 DKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDTQVLLWN 396 DK + W +P + S L GH V + + + +V+G D + +W Sbjct: 234 DKIEKNWNANP-----IMGSAVLRGHEDHVITCM------QIHDDVLVTGSDDNTLKVWC 282 Query: 397 LHTGEVAGTMKGHTSQVTGLAIDDNGD-IISSSMD 498 + GEV T+ GHT V I G I+S S D Sbjct: 283 IDKGEVMYTLVGHTGGVWTSQISQCGRYIVSGSTD 317
>SCON2_NEUCR (Q01277) Sulfur controller 2 (SCON2)| Length = 650 Score = 57.8 bits (138), Expect = 2e-08 Identities = 37/121 (30%), Positives = 62/121 (51%) Frame = +1 Query: 127 YHLSAQLHGHEDDVRGICICGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFV 306 Y LS L GHE+ V + + ++ +AT S D T++ W E+ +TLVGH++ + Sbjct: 285 YKLSV-LKGHENGVTCLQLDDNI-LATGSYDTTIKIWNIETEE-----CIRTLVGHTAGI 337 Query: 307 GPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIIS 486 + +F + ++SG +D + +WN HTGE T HT V + D G +++ Sbjct: 338 RAL-------QFDDSKLISGSLDHTIKVWNWHTGECLSTFAAHTDSVISVHFD--GHLLA 388 Query: 487 S 489 S Sbjct: 389 S 389 Score = 35.0 bits (79), Expect = 0.11 Identities = 30/103 (29%), Positives = 44/103 (42%) Frame = +1 Query: 154 HEDDVRGICICGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPS 333 H D V + G + +A+ S DKTV+ + + K Y L GHS +V Sbjct: 373 HTDSVISVHFDGHL-LASGSSDKTVKIFDFN--SKETYCLK----GHSDWVNST-----H 420 Query: 334 DRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAI 462 + S DT + LW+L T +V T +GH V + I Sbjct: 421 VDIKSRTVFSASDDTTIKLWDLDTRQVIRTYEGHVGHVQQVLI 463 Score = 34.7 bits (78), Expect = 0.15 Identities = 33/125 (26%), Positives = 48/125 (38%), Gaps = 12/125 (9%) Frame = +1 Query: 133 LSAQLHGHEDDVRGICICGDVGVATSSR------------DKTVRFWTQHPEKKREYVLS 276 L + L ++DVR + G VA SR D T+R W + Sbjct: 519 LPSSLPSGDEDVRHLY--GSAFVADESRPLPPRYFMTGGLDSTMRLWDSATGR-----CL 571 Query: 277 KTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGL 456 +TL GH V W+ D ++SG D V W +G+ T GH VT + Sbjct: 572 RTLFGHLEGV----WSLAGDTI---RVISGANDGMVKTWEPRSGKCDATYTGHCGPVTCV 624 Query: 457 AIDDN 471 + D+ Sbjct: 625 GLSDS 629 Score = 32.3 bits (72), Expect = 0.73 Identities = 20/59 (33%), Positives = 29/59 (49%) Frame = +1 Query: 322 APPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSSMD 498 A S P ++GG+D+ + LW+ TG T+ GH V LA D +IS + D Sbjct: 540 ADESRPLPPRYFMTGGLDSTMRLWDSATGRCLRTLFGHLEGVWSLA-GDTIRVISGAND 597
>GBLP_MEDSA (O24076) Guanine nucleotide-binding protein beta subunit-like| protein Length = 325 Score = 57.0 bits (136), Expect = 3e-08 Identities = 41/125 (32%), Positives = 57/125 (45%), Gaps = 3/125 (2%) Frame = +1 Query: 133 LSAQLHGHEDDVRGICICGDVG--VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFV 306 L + H D V I D + T+SRDK++ W E K V + L GHS FV Sbjct: 7 LRGTMRAHTDVVTAIATPIDNSDMIVTASRDKSIILWHLTKEDKTYGVPRRRLTGHSHFV 66 Query: 307 GPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAID-DNGDII 483 +V + +SG D ++ LW+L+ G A GHT V +A DN I+ Sbjct: 67 QDVVLSSDGQ-----FALSGSWDGELRLWDLNAGTSARRFVGHTKDVLSVAFSIDNRQIV 121 Query: 484 SSSMD 498 S+S D Sbjct: 122 SASRD 126 Score = 50.8 bits (120), Expect = 2e-06 Identities = 33/114 (28%), Positives = 57/114 (50%), Gaps = 1/114 (0%) Frame = +1 Query: 151 GHEDDVRGICICGDVG-VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAP 327 GH DV + D + ++SRD+T++ W E K Y + HS +V + ++P Sbjct: 103 GHTKDVLSVAFSIDNRQIVSASRDRTIKLWNTLGECK--YTIQDG-DAHSDWVSCVRFSP 159 Query: 328 PSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISS 489 + P+ IVS D V +WNL ++ T+ GH+ V +A+ +G + +S Sbjct: 160 ST---PQPTIVSASWDRTVKVWNLTNCKLRNTLAGHSGYVNTVAVSPDGSLCAS 210 Score = 37.7 bits (86), Expect = 0.017 Identities = 24/72 (33%), Positives = 38/72 (52%), Gaps = 1/72 (1%) Frame = +1 Query: 199 VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAI-VSGGMD 375 + ++S D+TV+ W K R TL GHS +V + +P +G++ SGG D Sbjct: 166 IVSASWDRTVKVWNLTNCKLRN-----TLAGHSGYVNTVAVSP------DGSLCASGGKD 214 Query: 376 TQVLLWNLHTGE 411 +LLW+L G+ Sbjct: 215 GVILLWDLAEGK 226
>Y2124_ANASP (Q8YV57) Hypothetical WD-repeat protein all2124| Length = 1683 Score = 57.0 bits (136), Expect = 3e-08 Identities = 33/102 (32%), Positives = 56/102 (54%) Frame = +1 Query: 187 GDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSG 366 GD+ +A+++ DKTV+ W + R+ KTL+GH + V + ++P + S Sbjct: 1416 GDL-IASANADKTVKIW-----RVRDGKALKTLIGHDNEVNKVNFSPDGK-----TLASA 1464 Query: 367 GMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSS 492 D V LWN+ G+ T+KGHT +V ++ +G II+S+ Sbjct: 1465 SRDNTVKLWNVSDGKFKKTLKGHTDEVFWVSFSPDGKIIASA 1506 Score = 54.3 bits (129), Expect = 2e-07 Identities = 36/118 (30%), Positives = 56/118 (47%), Gaps = 1/118 (0%) Frame = +1 Query: 142 QLHGHEDDVRGICICGD-VGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMV 318 +L GH+D V I I D +A+ S DKT++ W+ R+ L +TL GH V + Sbjct: 1067 RLEGHKDGVISISISRDGQTIASGSLDKTIKLWS------RDGRLFRTLNGHEDAVYSVS 1120 Query: 319 WAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSS 492 ++P I SGG D + LW G + T+ GH V + +G ++S+ Sbjct: 1121 FSPDGQ-----TIASGGSDKTIKLWQTSDGTLLKTITGHEQTVNNVYFSPDGKNLASA 1173 Score = 51.6 bits (122), Expect = 1e-06 Identities = 29/98 (29%), Positives = 46/98 (46%) Frame = +1 Query: 199 VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDT 378 +A S DKTV+ W + K L KTL GH +V + ++P + S D Sbjct: 1212 IAAGSEDKTVKLWHRQDGK-----LLKTLNGHQDWVNSLSFSPDGK-----TLASASADK 1261 Query: 379 QVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSS 492 + LW + G++ T+KGH V + +G I+S+ Sbjct: 1262 TIKLWRIADGKLVKTLKGHNDSVWDVNFSSDGKAIASA 1299 Score = 51.2 bits (121), Expect = 2e-06 Identities = 30/119 (25%), Positives = 56/119 (47%), Gaps = 1/119 (0%) Frame = +1 Query: 145 LHGHEDDVRGICICGD-VGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVW 321 L+GHED V + D +A+ DKT++ W + + L KT+ GH V + + Sbjct: 1109 LNGHEDAVYSVSFSPDGQTIASGGSDKTIKLW-----QTSDGTLLKTITGHEQTVNNVYF 1163 Query: 322 APPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSSMD 498 +P + S D + LW+ +G++ T+ GH++ V + +G I++ + Sbjct: 1164 SPDGKN-----LASASSDHSIKLWDTTSGQLLMTLTGHSAGVITVRFSPDGQTIAAGSE 1217 Score = 46.6 bits (109), Expect = 4e-05 Identities = 33/119 (27%), Positives = 52/119 (43%), Gaps = 1/119 (0%) Frame = +1 Query: 145 LHGHEDDVRGICICGDVGV-ATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVW 321 L GH D+V + D + A++S DKT+R W L K+L H+ V + + Sbjct: 1484 LKGHTDEVFWVSFSPDGKIIASASADKTIRLWDSFSGN-----LIKSLPAHNDLVYSVNF 1538 Query: 322 APPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSSMD 498 P + S D V LW H G + T GH++ V + +G I+S+ + Sbjct: 1539 NPDGSM-----LASTSADKTVKLWRSHDGHLLHTFSGHSNVVYSSSFSPDGRYIASASE 1592 Score = 46.6 bits (109), Expect = 4e-05 Identities = 31/115 (26%), Positives = 53/115 (46%), Gaps = 1/115 (0%) Frame = +1 Query: 151 GHEDDVRGICICGD-VGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAP 327 GHE V + D +A++S D +++ W + L TL GHS+ V + ++P Sbjct: 1153 GHEQTVNNVYFSPDGKNLASASSDHSIKLWDTTSGQ-----LLMTLTGHSAGVITVRFSP 1207 Query: 328 PSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSS 492 I +G D V LW+ G++ T+ GH V L+ +G ++S+ Sbjct: 1208 DGQ-----TIAAGSEDKTVKLWHRQDGKLLKTLNGHQDWVNSLSFSPDGKTLASA 1257 Score = 40.0 bits (92), Expect = 0.004 Identities = 31/117 (26%), Positives = 53/117 (45%), Gaps = 1/117 (0%) Frame = +1 Query: 145 LHGHEDDVRGICICGD-VGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVW 321 L GH D V + D +A++SRD T++ W +H + +T GHS V + + Sbjct: 1277 LKGHNDSVWDVNFSSDGKAIASASRDNTIKLWNRHG------IELETFTGHSGGVYAVNF 1330 Query: 322 APPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSS 492 P S+ I S +D + LW + G+ S V ++ +G II+++ Sbjct: 1331 LPDSN-----IIASASLDNTIRLWQRPLISPLEVLAGN-SGVYAVSFLHDGSIIATA 1381 Score = 31.6 bits (70), Expect = 1.2 Identities = 28/112 (25%), Positives = 47/112 (41%), Gaps = 1/112 (0%) Frame = +1 Query: 130 HLSAQLHGHEDDVRGICICGDVG-VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFV 306 HL GH + V D +A++S DKTV+ W + + L TL H + V Sbjct: 1563 HLLHTFSGHSNVVYSSSFSPDGRYIASASEDKTVKIW------QIDGHLLTTLPQHQAGV 1616 Query: 307 GPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAI 462 +++P ++SG +DT +W + + TSQ+ L + Sbjct: 1617 MSAIFSPDGK-----TLISGSLDTTTKIWRF------DSQQAKTSQMNTLVM 1657
>GBLP_TRYBR (P69104) Guanine nucleotide-binding protein beta subunit-like| protein (Activated protein kinase C receptor homolog) (Track) Length = 318 Score = 56.2 bits (134), Expect = 5e-08 Identities = 35/115 (30%), Positives = 57/115 (49%), Gaps = 1/115 (0%) Frame = +1 Query: 151 GHEDDVRGICICGDVG-VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAP 327 GH DV + D + + RD +R W K E + + + H+ +V + ++P Sbjct: 107 GHTKDVLSVAFSPDNRQIVSGGRDNALRVWNV----KGECMHTLSRGAHTDWVSCVRFSP 162 Query: 328 PSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSS 492 D IVSGG D V +W+L TG + +KGHT+ VT + + +G + +SS Sbjct: 163 SLDA---PVIVSGGWDNLVKVWDLATGRLVTDLKGHTNYVTSVTVSPDGSLCASS 214 Score = 48.1 bits (113), Expect = 1e-05 Identities = 34/105 (32%), Positives = 49/105 (46%), Gaps = 5/105 (4%) Frame = +1 Query: 199 VATSSRDKTVRFWTQHPEKKRE---YVL-SKTLVGHSSFVGPMVWAPPSDRFPEGAIVSG 366 V ++SRDKT+ W +P++ Y L + L GHS+FV + + + VS Sbjct: 31 VVSTSRDKTLLSWGPNPDRHSSECSYGLPDRRLEGHSAFVSDVALSNNGN-----FAVSA 85 Query: 367 GMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAID-DNGDIISSSMD 498 D + LWNL G+ GHT V +A DN I+S D Sbjct: 86 SWDHSLRLWNLQNGQCQYKFLGHTKDVLSVAFSPDNRQIVSGGRD 130
>GBLP_TRYBB (P69103) Guanine nucleotide-binding protein beta subunit-like| protein (Activated protein kinase C receptor homolog) Length = 318 Score = 56.2 bits (134), Expect = 5e-08 Identities = 35/115 (30%), Positives = 57/115 (49%), Gaps = 1/115 (0%) Frame = +1 Query: 151 GHEDDVRGICICGDVG-VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAP 327 GH DV + D + + RD +R W K E + + + H+ +V + ++P Sbjct: 107 GHTKDVLSVAFSPDNRQIVSGGRDNALRVWNV----KGECMHTLSRGAHTDWVSCVRFSP 162 Query: 328 PSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSS 492 D IVSGG D V +W+L TG + +KGHT+ VT + + +G + +SS Sbjct: 163 SLDA---PVIVSGGWDNLVKVWDLATGRLVTDLKGHTNYVTSVTVSPDGSLCASS 214 Score = 48.1 bits (113), Expect = 1e-05 Identities = 34/105 (32%), Positives = 49/105 (46%), Gaps = 5/105 (4%) Frame = +1 Query: 199 VATSSRDKTVRFWTQHPEKKRE---YVL-SKTLVGHSSFVGPMVWAPPSDRFPEGAIVSG 366 V ++SRDKT+ W +P++ Y L + L GHS+FV + + + VS Sbjct: 31 VVSTSRDKTLLSWGPNPDRHSSECSYGLPDRRLEGHSAFVSDVALSNNGN-----FAVSA 85 Query: 367 GMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAID-DNGDIISSSMD 498 D + LWNL G+ GHT V +A DN I+S D Sbjct: 86 SWDHSLRLWNLQNGQCQYKFLGHTKDVLSVAFSPDNRQIVSGGRD 130
>PKWA_THECU (P49695) Probable serine/threonine-protein kinase pkwA (EC| 2.7.11.1) Length = 742 Score = 55.8 bits (133), Expect = 6e-08 Identities = 37/121 (30%), Positives = 60/121 (49%), Gaps = 1/121 (0%) Frame = +1 Query: 139 AQLHGHEDDVRGICICGDVG-VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPM 315 A L GH D V + D VA+ SRD T+R W K+R+ L + V + Sbjct: 579 AVLKGHTDYVYAVAFSPDGSMVASGSRDGTIRLWDVATGKERD-----VLQAPAENVVSL 633 Query: 316 VWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSSM 495 ++P +G+++ G D+ V LW++ +GE T +GHT V +A +G +++S Sbjct: 634 AFSP------DGSMLVHGSDSTVHLWDVASGEALHTFEGHTDWVRAVAFSPDGALLASGS 687 Query: 496 D 498 D Sbjct: 688 D 688 Score = 55.5 bits (132), Expect = 8e-08 Identities = 35/116 (30%), Positives = 53/116 (45%), Gaps = 1/116 (0%) Frame = +1 Query: 145 LHGHEDDVRGICICGDVGV-ATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVW 321 L GH D VR + D + A+ S D TVR W ++R GH+ +V + + Sbjct: 497 LEGHTDWVRAVAFSPDGALLASGSDDATVRLWDVAAAEERA-----VFEGHTHYVLDIAF 551 Query: 322 APPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISS 489 +P + SG D LWN+ TG +KGHT V +A +G +++S Sbjct: 552 SPDGSM-----VASGSRDGTARLWNVATGTEHAVLKGHTDYVYAVAFSPDGSMVAS 602 Score = 37.4 bits (85), Expect = 0.023 Identities = 16/53 (30%), Positives = 33/53 (62%), Gaps = 1/53 (1%) Frame = +1 Query: 343 PEGAIVSGGM-DTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSSMD 498 P G++++GG D + +W++ +G+ T++GHT V +A +G +++S D Sbjct: 469 PGGSLLAGGSGDKLIHVWDVASGDELHTLEGHTDWVRAVAFSPDGALLASGSD 521
>GBLP_BRANA (Q39336) Guanine nucleotide-binding protein beta subunit-like| protein Length = 327 Score = 55.1 bits (131), Expect = 1e-07 Identities = 34/114 (29%), Positives = 59/114 (51%), Gaps = 1/114 (0%) Frame = +1 Query: 151 GHEDDVRGICICGDVG-VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAP 327 GH DV + D + ++SRD+T++ W E K Y +S+ GH +V + ++P Sbjct: 103 GHTKDVLSVAFSLDNRQIVSASRDRTIKLWNTLGECK--YTISEGGEGHRDWVSCVRFSP 160 Query: 328 PSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISS 489 + + IVS D V +WNL ++ T+ GHT V+ +A+ +G + +S Sbjct: 161 NT---LQPTIVSASCDKTVKVWNLSNCKLRSTLAGHTGYVSTVAVSPDGSLCAS 211 Score = 52.8 bits (125), Expect = 5e-07 Identities = 38/125 (30%), Positives = 55/125 (44%), Gaps = 3/125 (2%) Frame = +1 Query: 133 LSAQLHGHEDDVRGIC--ICGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFV 306 L + H D V I I + ++SRDK++ W + K V + L GHS FV Sbjct: 7 LKGTMRAHTDMVTAIATPIDNSDTIVSASRDKSIIVWKLTKDDKSYGVRQRRLTGHSHFV 66 Query: 307 GPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAID-DNGDII 483 +V + +SG D ++ LW+L G GHT V +A DN I+ Sbjct: 67 EDVVLSSDGQ-----FALSGSWDGELRLWDLAAGVSTRRFVGHTKDVLSVAFSLDNRQIV 121 Query: 484 SSSMD 498 S+S D Sbjct: 122 SASRD 126 Score = 39.3 bits (90), Expect = 0.006 Identities = 31/99 (31%), Positives = 47/99 (47%), Gaps = 4/99 (4%) Frame = +1 Query: 127 YHLSAQLHGHEDDVRGICICGDV---GVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHS 297 Y +S GH D V + + + ++S DKTV+ W K R TL GH+ Sbjct: 140 YTISEGGEGHRDWVSCVRFSPNTLQPTIVSASCDKTVKVWNLSNCKLRS-----TLAGHT 194 Query: 298 SFVGPMVWAPPSDRFPEGAI-VSGGMDTQVLLWNLHTGE 411 +V + +P +G++ SGG D VLLW+L G+ Sbjct: 195 GYVSTVAVSP------DGSLCASGGKDGVVLLWDLAEGK 227
>GBLP_ARATH (O24456) Guanine nucleotide-binding protein beta subunit-like| protein (WD-40 repeat auxin-dependent protein ARCA) Length = 327 Score = 55.1 bits (131), Expect = 1e-07 Identities = 34/114 (29%), Positives = 59/114 (51%), Gaps = 1/114 (0%) Frame = +1 Query: 151 GHEDDVRGICICGDVG-VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAP 327 GH DV + D + ++SRD+T++ W E K Y +S+ GH +V + ++P Sbjct: 103 GHTKDVLSVAFSLDNRQIVSASRDRTIKLWNTLGECK--YTISEGGEGHRDWVSCVRFSP 160 Query: 328 PSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISS 489 + + IVS D V +WNL ++ T+ GHT V+ +A+ +G + +S Sbjct: 161 NT---LQPTIVSASWDKTVKVWNLSNCKLRSTLAGHTGYVSTVAVSPDGSLCAS 211 Score = 53.1 bits (126), Expect = 4e-07 Identities = 38/125 (30%), Positives = 55/125 (44%), Gaps = 3/125 (2%) Frame = +1 Query: 133 LSAQLHGHEDDVRGICICGDVG--VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFV 306 L + H D V I D + ++SRDK++ W + K V + L GHS FV Sbjct: 7 LKGTMRAHTDMVTAIATPIDNADIIVSASRDKSIILWKLTKDDKAYGVAQRRLTGHSHFV 66 Query: 307 GPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAID-DNGDII 483 +V + +SG D ++ LW+L G GHT V +A DN I+ Sbjct: 67 EDVVLSSDGQ-----FALSGSWDGELRLWDLAAGVSTRRFVGHTKDVLSVAFSLDNRQIV 121 Query: 484 SSSMD 498 S+S D Sbjct: 122 SASRD 126 Score = 39.3 bits (90), Expect = 0.006 Identities = 31/99 (31%), Positives = 47/99 (47%), Gaps = 4/99 (4%) Frame = +1 Query: 127 YHLSAQLHGHEDDVRGICICGDV---GVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHS 297 Y +S GH D V + + + ++S DKTV+ W K R TL GH+ Sbjct: 140 YTISEGGEGHRDWVSCVRFSPNTLQPTIVSASWDKTVKVWNLSNCKLRS-----TLAGHT 194 Query: 298 SFVGPMVWAPPSDRFPEGAI-VSGGMDTQVLLWNLHTGE 411 +V + +P +G++ SGG D VLLW+L G+ Sbjct: 195 GYVSTVAVSP------DGSLCASGGKDGVVLLWDLAEGK 227
>GBLP_SOYBN (Q39836) Guanine nucleotide-binding protein beta subunit-like| protein Length = 325 Score = 55.1 bits (131), Expect = 1e-07 Identities = 40/125 (32%), Positives = 56/125 (44%), Gaps = 3/125 (2%) Frame = +1 Query: 133 LSAQLHGHEDDVRGICICGDVG--VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFV 306 L + H D V I D + T+SRD+++ W E K V + L GHS FV Sbjct: 7 LKGTMRAHTDVVTAIATPIDNSDMIVTASRDRSIILWHLTKEDKTYGVPRRRLTGHSHFV 66 Query: 307 GPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAID-DNGDII 483 +V + +SG D ++ LW+L G A GHT V +A DN I+ Sbjct: 67 QDVVLSSDGQ-----FALSGSWDGELRLWDLAAGTSARRFVGHTKDVLSVAFSIDNRQIV 121 Query: 484 SSSMD 498 S+S D Sbjct: 122 SASRD 126 Score = 47.0 bits (110), Expect = 3e-05 Identities = 34/125 (27%), Positives = 60/125 (48%), Gaps = 1/125 (0%) Frame = +1 Query: 118 MAAYHLSAQLHGHEDDVRGICICGDVG-VATSSRDKTVRFWTQHPEKKREYVLSKTLVGH 294 +AA + + GH DV + D + ++SRD+T++ W E K Y + H Sbjct: 92 LAAGTSARRFVGHTKDVLSVAFSIDNRQIVSASRDRTIKLWNTLGECK--YTIQDG-DAH 148 Query: 295 SSFVGPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNG 474 S +V + ++P + + IVS D V +WNL ++ T+ GH V +A+ +G Sbjct: 149 SDWVSCVRFSPST---LQPTIVSASWDRTVKVWNLTNCKLRNTLAGHNGYVNTVAVSPDG 205 Query: 475 DIISS 489 + +S Sbjct: 206 SLCAS 210 Score = 36.6 bits (83), Expect = 0.039 Identities = 23/72 (31%), Positives = 38/72 (52%), Gaps = 1/72 (1%) Frame = +1 Query: 199 VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAI-VSGGMD 375 + ++S D+TV+ W K R TL GH+ +V + +P +G++ SGG D Sbjct: 166 IVSASWDRTVKVWNLTNCKLRN-----TLAGHNGYVNTVAVSP------DGSLCASGGKD 214 Query: 376 TQVLLWNLHTGE 411 +LLW+L G+ Sbjct: 215 GVILLWDLAEGK 226
>GBLP_TOBAC (P49026) Guanine nucleotide-binding protein beta subunit-like| protein Length = 326 Score = 55.1 bits (131), Expect = 1e-07 Identities = 41/125 (32%), Positives = 58/125 (46%), Gaps = 3/125 (2%) Frame = +1 Query: 133 LSAQLHGHEDDVRGICICGDVG--VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFV 306 L + H D V I D + TSSRDK++ W+ + + V + L GH FV Sbjct: 8 LRGTMRAHTDWVTAIATAVDNSDMIVTSSRDKSIIVWSITKDGPQYGVPRRRLTGHGHFV 67 Query: 307 GPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAID-DNGDII 483 +V + SD +SG D ++ LW+L G A GHT V +A DN I+ Sbjct: 68 QDVVLS--SDGM---FALSGSWDGELRLWDLQAGTTARRFVGHTKDVLSVAFSVDNRQIV 122 Query: 484 SSSMD 498 S+S D Sbjct: 123 SASRD 127 Score = 48.9 bits (115), Expect = 8e-06 Identities = 35/114 (30%), Positives = 56/114 (49%), Gaps = 1/114 (0%) Frame = +1 Query: 151 GHEDDVRGICICGDVG-VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAP 327 GH DV + D + ++SRDK++R W E K Y + HS +V + ++P Sbjct: 104 GHTKDVLSVAFSVDNRQIVSASRDKSIRLWNTLGECK--YTIQDG-DSHSDWVSCVRFSP 160 Query: 328 PSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISS 489 + + IVSG D V +WNL ++ T+ GHT V A+ +G + +S Sbjct: 161 NN---LQPTIVSGSWDRTVKIWNLTNCKLRLTLAGHTGYVNTPAVSPDGSLCAS 211 Score = 34.7 bits (78), Expect = 0.15 Identities = 23/72 (31%), Positives = 36/72 (50%), Gaps = 1/72 (1%) Frame = +1 Query: 199 VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAI-VSGGMD 375 + + S D+TV+ W K R TL GH+ +V +P +G++ SGG D Sbjct: 167 IVSGSWDRTVKIWNLTNCKLR-----LTLAGHTGYVNTPAVSP------DGSLCASGGKD 215 Query: 376 TQVLLWNLHTGE 411 +LLW+L G+ Sbjct: 216 GVILLWDLAEGK 227
>Y143_SYNY3 (P74442) Hypothetical WD-repeat protein slr0143| Length = 1191 Score = 54.3 bits (129), Expect = 2e-07 Identities = 38/135 (28%), Positives = 65/135 (48%), Gaps = 7/135 (5%) Frame = +1 Query: 109 APLMAAYHLSAQ------LHGHEDDVRGICICGDVG-VATSSRDKTVRFWTQHPEKKREY 267 +PL++ + +Q L GH D V + I +A++SRD TV WT E RE+ Sbjct: 538 SPLVSLQQILSQIAEKNVLTGHRDGVTSVAISSHKNLIASASRDGTVHLWTPQGEFLREF 597 Query: 268 VLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQV 447 GH+ + + ++P F + G D V +W+L G + T+KGH V Sbjct: 598 ------TGHTGSIYRVDFSPNGKIF-----ATAGQDQTVKIWDL-DGNLLQTLKGHQDSV 645 Query: 448 TGLAIDDNGDIISSS 492 ++ +G+I++S+ Sbjct: 646 YSVSFSPDGEILAST 660 Score = 40.8 bits (94), Expect = 0.002 Identities = 27/96 (28%), Positives = 47/96 (48%) Frame = +1 Query: 199 VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDT 378 +A ++ D TVR WT E K TL GH FV +V+ P + + S + Sbjct: 740 LAVAADDGTVRLWTPQGEIKA------TLSGHDEFVTRVVFTPDGKQ-----LFSSSSNG 788 Query: 379 QVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIIS 486 V+ W+ +G++ +G+ + GLA+ NG +++ Sbjct: 789 SVIHWST-SGKMLKKYQGYPEAIFGLALASNGALLA 823 Score = 36.6 bits (83), Expect = 0.039 Identities = 28/91 (30%), Positives = 41/91 (45%), Gaps = 1/91 (1%) Frame = +1 Query: 130 HLSAQLHGHEDDVRGICICGDVGV-ATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFV 306 +L L GH+D V + D + A++SRD+TVR W K L GH+ V Sbjct: 633 NLLQTLKGHQDSVYSVSFSPDGEILASTSRDRTVRLWHWRSGK-----TLAVLGGHTKSV 687 Query: 307 GPMVWAPPSDRFPEGAIVSGGMDTQVLLWNL 399 ++P +VS D Q+ LW+L Sbjct: 688 DDAQFSPDGQ-----TLVSVCRDGQIRLWDL 713
>GBLP_NICPL (P93340) Guanine nucleotide-binding protein beta subunit-like| protein Length = 326 Score = 54.3 bits (129), Expect = 2e-07 Identities = 41/125 (32%), Positives = 58/125 (46%), Gaps = 3/125 (2%) Frame = +1 Query: 133 LSAQLHGHEDDVRGICICGDVG--VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFV 306 L + H D V I D + TSSRDK++ W+ + + V + L GH FV Sbjct: 8 LRGTMRAHTDWVTAIATPVDNSDMIVTSSRDKSIIVWSLTKDGPQYGVPRRRLTGHGHFV 67 Query: 307 GPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAID-DNGDII 483 +V + SD +SG D ++ LW+L G A GHT V +A DN I+ Sbjct: 68 QDVVLS--SDGM---FALSGSWDGELRLWDLQAGTTARRFVGHTKDVLSVAFSADNRQIV 122 Query: 484 SSSMD 498 S+S D Sbjct: 123 SASRD 127 Score = 53.5 bits (127), Expect = 3e-07 Identities = 35/114 (30%), Positives = 57/114 (50%), Gaps = 1/114 (0%) Frame = +1 Query: 151 GHEDDVRGICICGDVG-VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAP 327 GH DV + D + ++SRDK++R W E K Y++ HS +V + ++P Sbjct: 104 GHTKDVLSVAFSADNRQIVSASRDKSIRLWNTLGECK--YIIQDG-DSHSDWVSCVRFSP 160 Query: 328 PSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISS 489 + + IVSG D V +WNL ++ T+ GHT V A+ +G + +S Sbjct: 161 NN---LQPTIVSGSWDRTVKIWNLTNCKLRATLAGHTGYVNTTAVSPDGSLCAS 211 Score = 35.4 bits (80), Expect = 0.086 Identities = 23/72 (31%), Positives = 36/72 (50%), Gaps = 1/72 (1%) Frame = +1 Query: 199 VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAI-VSGGMD 375 + + S D+TV+ W K R TL GH+ +V +P +G++ SGG D Sbjct: 167 IVSGSWDRTVKIWNLTNCKLRA-----TLAGHTGYVNTTAVSP------DGSLCASGGKD 215 Query: 376 TQVLLWNLHTGE 411 +LLW+L G+ Sbjct: 216 GVILLWDLAEGK 227
>POP1_SCHPO (P87060) WD-repeat protein pop1| Length = 775 Score = 53.1 bits (126), Expect = 4e-07 Identities = 33/109 (30%), Positives = 53/109 (48%) Frame = +1 Query: 145 LHGHEDDVRGICICGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWA 324 L GH D VR + GD+ + ++S D T+R W K V L GH V + Sbjct: 573 LRGHTDSVREVACLGDL-IVSASYDGTLRVW-----KASTGVCLHVLRGHVGRVYSVTIN 626 Query: 325 PPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDN 471 P + +S G D ++ +WNL +GE+ T+ GH++ V+ + + N Sbjct: 627 PSRQQ-----CISAGTDAKIRIWNLESGELLQTLHGHSNLVSQVTFNQN 670 Score = 32.0 bits (71), Expect = 0.95 Identities = 14/36 (38%), Positives = 20/36 (55%) Frame = +1 Query: 355 IVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAI 462 +V+G D V +W+L TGE GHTS + + I Sbjct: 459 LVTGSTDRTVRVWDLRTGECKQVFYGHTSTIRCIKI 494
>GBLP_YEAST (P38011) Guanine nucleotide-binding protein beta subunit-like| protein (Receptor of activated protein kinase C 1) (RACK1) (Receptor for activated C kinase) Length = 318 Score = 53.1 bits (126), Expect = 4e-07 Identities = 35/117 (29%), Positives = 58/117 (49%), Gaps = 3/117 (2%) Frame = +1 Query: 151 GHEDDVRGICICGDVGVATS-SRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAP 327 GH+ DV + I + S SRDKT++ WT + TL+GH+ +V V Sbjct: 104 GHKSDVMSVDIDKKASMIISGSRDKTIKVWTIKGQ------CLATLLGHNDWVS-QVRVV 156 Query: 328 PSDRFPEGA--IVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSS 492 P+++ + + I+S G D V WNL+ ++ GH S + L +G +I+S+ Sbjct: 157 PNEKADDDSVTIISAGNDKMVKAWNLNQFQIEADFIGHNSNINTLTASPDGTLIASA 213 Score = 38.9 bits (89), Expect = 0.008 Identities = 31/100 (31%), Positives = 45/100 (45%), Gaps = 2/100 (2%) Frame = +1 Query: 205 TSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAI-VSGGMDTQ 381 ++SRDKT+ W + ++ V ++ GHS V +GA +S D Sbjct: 34 SASRDKTLISWKLTGDDQKFGVPVRSFKGHSHIVQDCTLTA------DGAYALSASWDKT 87 Query: 382 VLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGD-IISSSMD 498 + LW++ TGE GH S V + ID IIS S D Sbjct: 88 LRLWDVATGETYQRFVGHKSDVMSVDIDKKASMIISGSRD 127
>Y2800_ANASP (Q8YTC2) Hypothetical WD-repeat protein alr2800| Length = 1258 Score = 53.1 bits (126), Expect = 4e-07 Identities = 34/120 (28%), Positives = 62/120 (51%), Gaps = 2/120 (1%) Frame = +1 Query: 139 AQLHGHEDDVRGICICGDVG-VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPM 315 + L GH D + GI D +A++S D +VR W + + +L H+ +V + Sbjct: 972 SSLEGHTDFIYGIAFSPDSQTLASASTDSSVRLWNISTGQCFQILLE-----HTDWVYAV 1026 Query: 316 VWAPPSDRFPEGAIVS-GGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSS 492 V+ P+G I++ G D V LWN+ TG+ T+ H+ ++ G+A +G +++S+ Sbjct: 1027 VF------HPQGKIIATGSADCTVKLWNISTGQCLKTLSEHSDKILGMAWSPDGQLLASA 1080 Score = 52.4 bits (124), Expect = 7e-07 Identities = 32/115 (27%), Positives = 55/115 (47%), Gaps = 1/115 (0%) Frame = +1 Query: 145 LHGHEDDVRGICICGD-VGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVW 321 L H VR + D +A+ S D+T++ W H + KT +GH++ V + + Sbjct: 806 LKSHTGWVRSVAFSADGQTLASGSGDRTIKIWNYHTGE-----CLKTYIGHTNSVYSIAY 860 Query: 322 APPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIIS 486 +P S +VSG D + LW+ T T+ GHT++V +A +G ++ Sbjct: 861 SPDSK-----ILVSGSGDRTIKLWDCQTHICIKTLHGHTNEVCSVAFSPDGQTLA 910 Score = 51.2 bits (121), Expect = 2e-06 Identities = 34/116 (29%), Positives = 53/116 (45%), Gaps = 1/116 (0%) Frame = +1 Query: 145 LHGHEDDVRGICICGDVG-VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVW 321 L GH D VR + D +A+S+ D T++ W K +TL H+ +V + + Sbjct: 764 LTGHTDWVRCVAFSPDGNTLASSAADHTIKLWDVSQGK-----CLRTLKSHTGWVRSVAF 818 Query: 322 APPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISS 489 + + SG D + +WN HTGE T GHT+ V +A + I+ S Sbjct: 819 SADGQ-----TLASGSGDRTIKIWNYHTGECLKTYIGHTNSVYSIAYSPDSKILVS 869 Score = 50.8 bits (120), Expect = 2e-06 Identities = 33/117 (28%), Positives = 58/117 (49%), Gaps = 2/117 (1%) Frame = +1 Query: 145 LHGHEDDVRGICIC--GDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMV 318 L GH + V G++ +AT S D+TV+ W K KTL GH+++V + Sbjct: 1100 LRGHSNRVYSAIFSPNGEI-IATCSTDQTVKIWDWQQGK-----CLKTLTGHTNWVFDIA 1153 Query: 319 WAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISS 489 ++P + S D V +W+++TG+ GHT V+ +A +G++++S Sbjct: 1154 FSPDGK-----ILASASHDQTVRIWDVNTGKCHHICIGHTHLVSSVAFSPDGEVVAS 1205 Score = 50.8 bits (120), Expect = 2e-06 Identities = 30/97 (30%), Positives = 45/97 (46%) Frame = +1 Query: 199 VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDT 378 +AT S D TV+ W + KTL HS + M W+P + S D Sbjct: 1035 IATGSADCTVKLWNISTGQ-----CLKTLSEHSDKILGMAWSPDGQ-----LLASASADQ 1084 Query: 379 QVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISS 489 V LW+ TG G ++GH+++V NG+II++ Sbjct: 1085 SVRLWDCCTGRCVGILRGHSNRVYSAIFSPNGEIIAT 1121 Score = 48.1 bits (113), Expect = 1e-05 Identities = 31/117 (26%), Positives = 55/117 (47%), Gaps = 1/117 (0%) Frame = +1 Query: 145 LHGHEDDVRGICICGD-VGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVW 321 LHGH ++V + D +A S D++VR W R K G++ + P+ + Sbjct: 890 LHGHTNEVCSVAFSPDGQTLACVSLDQSVRLWNC-----RTGQCLKAWYGNTDWALPVAF 944 Query: 322 APPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSS 492 +P + SG D V LW+ TG+ +++GHT + G+A + ++S+ Sbjct: 945 SPDRQ-----ILASGSNDKTVKLWDWQTGKYISSLEGHTDFIYGIAFSPDSQTLASA 996 Score = 47.0 bits (110), Expect = 3e-05 Identities = 32/115 (27%), Positives = 53/115 (46%), Gaps = 1/115 (0%) Frame = +1 Query: 151 GHEDDVRGICICGDVGV-ATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAP 327 GH + VR + D + A+ D+ V+ W+ R+ V KTL GH V + + P Sbjct: 682 GHSNWVRFVVFSPDGEILASCGADENVKLWSV-----RDGVCIKTLTGHEHEVFSVAFHP 736 Query: 328 PSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSS 492 + + S D + LW++ G T+ GHT V +A +G+ ++SS Sbjct: 737 DGE-----TLASASGDKTIKLWDIQDGTCLQTLTGHTDWVRCVAFSPDGNTLASS 786 Score = 41.2 bits (95), Expect = 0.002 Identities = 27/90 (30%), Positives = 42/90 (46%), Gaps = 1/90 (1%) Frame = +1 Query: 145 LHGHEDDVRGICICGDVGV-ATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVW 321 L GH + V I D + A++S D+TVR W + K +GH+ V + + Sbjct: 1142 LTGHTNWVFDIAFSPDGKILASASHDQTVRIWDVNTGKCHHIC-----IGHTHLVSSVAF 1196 Query: 322 APPSDRFPEGAIVSGGMDTQVLLWNLHTGE 411 +P + + SG D V +WN+ TGE Sbjct: 1197 SPDGE-----VVASGSQDQTVRIWNVKTGE 1221 Score = 40.4 bits (93), Expect = 0.003 Identities = 31/117 (26%), Positives = 55/117 (47%), Gaps = 1/117 (0%) Frame = +1 Query: 145 LHGHEDDVRGICICGDVGV-ATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVW 321 L H D + G+ D + A++S D++VR W + L GHS+ V ++ Sbjct: 1058 LSEHSDKILGMAWSPDGQLLASASADQSVRLWDCCTGR-----CVGILRGHSNRVYSAIF 1112 Query: 322 APPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSS 492 +P + I + D V +W+ G+ T+ GHT+ V +A +G I++S+ Sbjct: 1113 SPNGE-----IIATCSTDQTVKIWDWQQGKCLKTLTGHTNWVFDIAFSPDGKILASA 1164 Score = 40.4 bits (93), Expect = 0.003 Identities = 28/98 (28%), Positives = 46/98 (46%) Frame = +1 Query: 199 VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDT 378 +AT D VR W K L GHS++V +V++P + + S G D Sbjct: 657 LATCDTDCHVRVWEVKSGK-----LLLICRGHSNWVRFVVFSPDGE-----ILASCGADE 706 Query: 379 QVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSS 492 V LW++ G T+ GH +V +A +G+ ++S+ Sbjct: 707 NVKLWSVRDGVCIKTLTGHEHEVFSVAFHPDGETLASA 744
>GBLP_SCHPO (Q10281) Guanine nucleotide-binding protein beta subunit-like| protein (Receptor of activated protein kinase C) Length = 314 Score = 52.8 bits (125), Expect = 5e-07 Identities = 37/117 (31%), Positives = 56/117 (47%), Gaps = 1/117 (0%) Frame = +1 Query: 142 QLHGHEDDVRGICICGDVG-VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMV 318 Q GH DV + I D V + SRDKT++ W K Y ++ GHS +V + Sbjct: 100 QFVGHTSDVLSVSISPDNRQVVSGSRDKTIKIWNIIGNCK--YTITDG--GHSDWVSCVR 155 Query: 319 WAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISS 489 ++P D VS G D V +W+L T + + GHT V+ + I +G + +S Sbjct: 156 FSPNPDNL---TFVSAGWDKAVKVWDLETFSLRTSHYGHTGYVSAVTISPDGSLCAS 209 Score = 51.6 bits (122), Expect = 1e-06 Identities = 37/125 (29%), Positives = 53/125 (42%), Gaps = 3/125 (2%) Frame = +1 Query: 133 LSAQLHGHEDDVRGICICGDVG--VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFV 306 L A L GH V + + + + SRDK++ W + V + L GHS FV Sbjct: 7 LRATLEGHSGWVTSLSTAPENPDILLSGSRDKSIILWNLVRDDVNYGVAQRRLTGHSHFV 66 Query: 307 GPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAID-DNGDII 483 + F +S D + LW+L GE GHTS V ++I DN ++ Sbjct: 67 SDCALS-----FDSHYALSASWDKTIRLWDLEKGECTHQFVGHTSDVLSVSISPDNRQVV 121 Query: 484 SSSMD 498 S S D Sbjct: 122 SGSRD 126
>TUP1_CANAL (P56093) Transcriptional repressor TUP1| Length = 514 Score = 52.8 bits (125), Expect = 5e-07 Identities = 33/124 (26%), Positives = 57/124 (45%), Gaps = 6/124 (4%) Frame = +1 Query: 148 HGHEDDVRGICICGD-VGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWA 324 +GHED V + + +A+ S D+TV+ W + ++ T +GH FV + Sbjct: 386 NGHEDSVYSVAFSNNGEQIASGSLDRTVKLWHLEGKSDKKSTCEVTYIGHKDFVLSVCCT 445 Query: 325 PPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDN-----GDIISS 489 P ++ I+SG D V+ W+ +G ++GH + V +A+ N G + Sbjct: 446 PDNE-----YILSGSKDRGVIFWDQASGNPLLMLQGHRNSVISVAVSLNSKGTEGIFATG 500 Query: 490 SMDC 501 S DC Sbjct: 501 SGDC 504 Score = 43.5 bits (101), Expect = 3e-04 Identities = 30/109 (27%), Positives = 53/109 (48%), Gaps = 1/109 (0%) Frame = +1 Query: 166 VRGICICGDVGV-ATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRF 342 +R +C D + AT + DK +R W ++ + K L GH + + + P DR Sbjct: 260 IRSVCFSPDGKLLATGAEDKLIRIWDLSTKR-----IIKILRGHEQDIYSLDFFPDGDR- 313 Query: 343 PEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISS 489 +VSG D V +W+L T + + T+ VT +A+ +G +I++ Sbjct: 314 ----LVSGSGDRSVRIWDLRTSQCSLTLSIEDG-VTTVAVSPDGKLIAA 357 Score = 30.0 bits (66), Expect = 3.6 Identities = 14/54 (25%), Positives = 31/54 (57%), Gaps = 2/54 (3%) Frame = +1 Query: 343 PEGAIVSGGMDTQVL-LWNLHTGEVAGTMKGHTSQVTGLAIDDNGD-IISSSMD 498 P+G +++ G + +++ +W+L T + ++GH + L +GD ++S S D Sbjct: 267 PDGKLLATGAEDKLIRIWDLSTKRIIKILRGHEQDIYSLDFFPDGDRLVSGSGD 320
>LUB1_SCHPO (O94289) Ubiquitin homeostasis protein lub1| Length = 713 Score = 52.8 bits (125), Expect = 5e-07 Identities = 35/127 (27%), Positives = 57/127 (44%) Frame = +1 Query: 118 MAAYHLSAQLHGHEDDVRGICICGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHS 297 M +Y LS +L GH+ DVRG+C + + ++SRD T W Q + + H Sbjct: 1 MTSYELSRELGGHKQDVRGVCSISNELIGSASRDGTYSVWEQINGEWTPHFYE----NHE 56 Query: 298 SFVGPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGD 477 FV + + P D+ GG D +L + T + + GH S + + ++ Sbjct: 57 GFVNCVCYVPAIDKNSR-----GGQDKCGILQEVGTNSPSYYLFGHESNICSASALNSET 111 Query: 478 IISSSMD 498 II+ S D Sbjct: 112 IITGSWD 118 Score = 39.3 bits (90), Expect = 0.006 Identities = 33/115 (28%), Positives = 48/115 (41%) Frame = +1 Query: 145 LHGHEDDVRGICICGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWA 324 L GH+ V + G+ T S DK ++ W + EK L K+++ H+ V + Sbjct: 133 LKGHQSSVWAVLALGEDIFITGSADKLIKIW--NGEK-----LVKSILAHNDCVRSLCQI 185 Query: 325 PPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISS 489 P G S D + LW GE + GHTS V L N +I+S Sbjct: 186 P-------GGFASCSNDGVIKLWT-SDGEFLYELHGHTSFVYSLTYIHNQQLIAS 232 Score = 31.2 bits (69), Expect = 1.6 Identities = 26/87 (29%), Positives = 34/87 (39%) Frame = +1 Query: 136 SAQLHGHEDDVRGICICGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPM 315 S L GHE ++ + T S D T R W K YVL GH S Sbjct: 91 SYYLFGHESNICSASALNSETIITGSWDSTARVWALGQCK---YVLK----GHQS----S 139 Query: 316 VWAPPSDRFPEGAIVSGGMDTQVLLWN 396 VWA + E ++G D + +WN Sbjct: 140 VWAVLA--LGEDIFITGSADKLIKIWN 164
>TAF5_MOUSE (Q8C092) Transcription initiation factor TFIID subunit 5| (Transcription initiation factor TFIID 100 kDa subunit) (TAF(II)100) (TAFII-100) (TAFII100) Length = 801 Score = 52.4 bits (124), Expect = 7e-07 Identities = 37/105 (35%), Positives = 55/105 (52%), Gaps = 5/105 (4%) Frame = +1 Query: 199 VATSSRDKTVRFWTQHPEKKREYVLSKTLV----GHSSFVGPMVWAPPSDRFPEGAIVSG 366 VAT S D+TVR W VL+ V GH + + ++P + RF + +G Sbjct: 643 VATGSADRTVRLWD---------VLNGNCVRIFTGHKGPIHSLTFSP-NGRF----LATG 688 Query: 367 GMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISS-SMD 498 D +VLLW++ G + G +KGHT V L +G+I++S SMD Sbjct: 689 ATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMD 733 Score = 29.6 bits (65), Expect = 4.7 Identities = 29/116 (25%), Positives = 44/116 (37%), Gaps = 1/116 (0%) Frame = +1 Query: 145 LHGHEDDVRGICICGDVG-VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVW 321 L+GH V G D + +SS D TVR W+ + + GH+ V + Sbjct: 540 LYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSL-----QTFTCLVGYKGHNYPVWDTQF 594 Query: 322 APPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISS 489 +P F VSGG D LW + GH + V N + +++ Sbjct: 595 SPYGYYF-----VSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRYHPNSNYVAT 645
>TAF5_HUMAN (Q15542) Transcription initiation factor TFIID subunit 5| (Transcription initiation factor TFIID 100 kDa subunit) (TAF(II)100) (TAFII-100) (TAFII100) Length = 800 Score = 52.4 bits (124), Expect = 7e-07 Identities = 37/105 (35%), Positives = 55/105 (52%), Gaps = 5/105 (4%) Frame = +1 Query: 199 VATSSRDKTVRFWTQHPEKKREYVLSKTLV----GHSSFVGPMVWAPPSDRFPEGAIVSG 366 VAT S D+TVR W VL+ V GH + + ++P + RF + +G Sbjct: 642 VATGSADRTVRLWD---------VLNGNCVRIFTGHKGPIHSLTFSP-NGRF----LATG 687 Query: 367 GMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISS-SMD 498 D +VLLW++ G + G +KGHT V L +G+I++S SMD Sbjct: 688 ATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMD 732 Score = 30.0 bits (66), Expect = 3.6 Identities = 29/116 (25%), Positives = 44/116 (37%), Gaps = 1/116 (0%) Frame = +1 Query: 145 LHGHEDDVRGICICGDVG-VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVW 321 L+GH V G D + +SS D TVR W+ + + GH+ V + Sbjct: 539 LYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSL-----QTFTCLVGYKGHNYPVWDTQF 593 Query: 322 APPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISS 489 +P F VSGG D LW + GH + V N + +++ Sbjct: 594 SPYGYYF-----VSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVAT 644
>FBXW7_HUMAN (Q969H0) F-box/WD-repeat protein 7 (F-box and WD-40 domain protein| 7) (F-box protein FBX30) (hCdc4) (Archipelago homolog) (hAgo) (SEL-10) Length = 707 Score = 52.0 bits (123), Expect = 9e-07 Identities = 38/119 (31%), Positives = 59/119 (49%), Gaps = 1/119 (0%) Frame = +1 Query: 145 LHGHEDDV-RGICICGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVW 321 L GH+D V + CG+ + + S D T++ W+ K +TLVGH+ V W Sbjct: 376 LKGHDDHVITCLQFCGN-RIVSGSDDNTLKVWSAVTGK-----CLRTLVGHTGGV----W 425 Query: 322 APPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSSMD 498 S + + I+SG D + +WN TGE T+ GHTS V + + + ++S S D Sbjct: 426 ---SSQMRDNIIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHLHEK-RVVSGSRD 480 Score = 44.3 bits (103), Expect = 2e-04 Identities = 35/118 (29%), Positives = 51/118 (43%), Gaps = 3/118 (2%) Frame = +1 Query: 145 LHGHEDDVRGICICGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWA 324 L GH + V + G + V + S D ++R W TL GH S M Sbjct: 537 LQGHTNRVYSLQFDG-IHVVSGSLDTSIRVWDVETGN-----CIHTLTGHQSLTSGM--- 587 Query: 325 PPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKG---HTSQVTGLAIDDNGDIISS 489 + +VSG D+ V +W++ TG+ T++G H S VT L + N I SS Sbjct: 588 ----ELKDNILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKNFVITSS 641 Score = 43.9 bits (102), Expect = 2e-04 Identities = 32/109 (29%), Positives = 50/109 (45%) Frame = +1 Query: 145 LHGHEDDVRGICICGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWA 324 L GH VR + G V + + D V+ W E TL GH++ V + Sbjct: 497 LMGHVAAVRCVQYDGR-RVVSGAYDFMVKVWDPETE-----TCLHTLQGHTNRVYSL--- 547 Query: 325 PPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDN 471 +F +VSG +DT + +W++ TG T+ GH S +G+ + DN Sbjct: 548 ----QFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKDN 592 Score = 37.4 bits (85), Expect = 0.023 Identities = 25/100 (25%), Positives = 44/100 (44%) Frame = +1 Query: 199 VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDT 378 + + S D+T++ W + TL GH+S V M E +VSG D Sbjct: 434 IISGSTDRTLKVWNAETGE-----CIHTLYGHTSTVRCM-------HLHEKRVVSGSRDA 481 Query: 379 QVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSSMD 498 + +W++ TG+ + GH + V + D ++S + D Sbjct: 482 TLRVWDIETGQCLHVLMGHVAAVRCVQYDGR-RVVSGAYD 520
>FBXW7_MOUSE (Q8VBV4) F-box/WD-repeat protein 7 (F-box and WD-40 domain protein| 7) (F-box protein FBW7) (F-box protein Fbxw6) (F-box-WD40 repeat protein 6) (SEL-10) Length = 629 Score = 52.0 bits (123), Expect = 9e-07 Identities = 38/119 (31%), Positives = 59/119 (49%), Gaps = 1/119 (0%) Frame = +1 Query: 145 LHGHEDDV-RGICICGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVW 321 L GH+D V + CG+ + + S D T++ W+ K +TLVGH+ V W Sbjct: 298 LKGHDDHVITCLQFCGN-RIVSGSDDNTLKVWSAVTGK-----CLRTLVGHTGGV----W 347 Query: 322 APPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSSMD 498 S + + I+SG D + +WN TGE T+ GHTS V + + + ++S S D Sbjct: 348 ---SSQMRDNIIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHLHEK-RVVSGSRD 402 Score = 44.3 bits (103), Expect = 2e-04 Identities = 35/118 (29%), Positives = 51/118 (43%), Gaps = 3/118 (2%) Frame = +1 Query: 145 LHGHEDDVRGICICGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWA 324 L GH + V + G + V + S D ++R W TL GH S M Sbjct: 459 LQGHTNRVYSLQFDG-IHVVSGSLDTSIRVWDVETGN-----CIHTLTGHQSLTSGM--- 509 Query: 325 PPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKG---HTSQVTGLAIDDNGDIISS 489 + +VSG D+ V +W++ TG+ T++G H S VT L + N I SS Sbjct: 510 ----ELKDNILVSGNADSTVKIWDIKTGQCLQTLQGPSKHQSAVTCLQFNKNFVITSS 563 Score = 43.9 bits (102), Expect = 2e-04 Identities = 32/109 (29%), Positives = 50/109 (45%) Frame = +1 Query: 145 LHGHEDDVRGICICGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWA 324 L GH VR + G V + + D V+ W E TL GH++ V + Sbjct: 419 LMGHVAAVRCVQYDGR-RVVSGAYDFMVKVWDPETE-----TCLHTLQGHTNRVYSL--- 469 Query: 325 PPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDN 471 +F +VSG +DT + +W++ TG T+ GH S +G+ + DN Sbjct: 470 ----QFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKDN 514 Score = 37.4 bits (85), Expect = 0.023 Identities = 25/100 (25%), Positives = 44/100 (44%) Frame = +1 Query: 199 VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDT 378 + + S D+T++ W + TL GH+S V M E +VSG D Sbjct: 356 IISGSTDRTLKVWNAETGE-----CIHTLYGHTSTVRCM-------HLHEKRVVSGSRDA 403 Query: 379 QVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSSMD 498 + +W++ TG+ + GH + V + D ++S + D Sbjct: 404 TLRVWDIETGQCLHVLMGHVAAVRCVQYDGR-RVVSGAYD 442
>POF1_SCHPO (P87053) F-box/WD-repeat protein pof1 (Skp1-binding protein 1)| Length = 605 Score = 52.0 bits (123), Expect = 9e-07 Identities = 36/119 (30%), Positives = 54/119 (45%) Frame = +1 Query: 145 LHGHEDDVRGICICGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWA 324 L GH D V + + ++ +A+ S D T+R W + L GHSS V + Sbjct: 269 LSGHSDGVMCLQLVRNI-LASGSYDATIRLWNL-----ATFQQVALLEGHSSGVTCL--- 319 Query: 325 PPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSSMDC 501 +F + ++SG MD + +WN T E + GHT V L D ++S S DC Sbjct: 320 ----QFDQCKLISGSMDKTIRIWNYRTSECISILHGHTDSVLCLTFDST-LLVSGSADC 373 Score = 41.2 bits (95), Expect = 0.002 Identities = 38/129 (29%), Positives = 55/129 (42%), Gaps = 2/129 (1%) Frame = +1 Query: 118 MAAYHLSAQLHGHEDDVRGICICGD-VGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGH 294 +A + A L GH V C+ D + + S DKT+R W + L GH Sbjct: 300 LATFQQVALLEGHSSGVT--CLQFDQCKLISGSMDKTIRIWNYRTSE-----CISILHGH 352 Query: 295 SSFVGPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGL-AIDDN 471 + V + F +VSG D V LW+ G+ T++GHT V + I D Sbjct: 353 TDSVLCLT-------FDSTLLVSGSADCTVKLWHFSGGKRI-TLRGHTGPVNSVRIIRDR 404 Query: 472 GDIISSSMD 498 G ++S S D Sbjct: 405 GLVLSGSDD 413 Score = 32.0 bits (71), Expect = 0.95 Identities = 26/108 (24%), Positives = 44/108 (40%), Gaps = 1/108 (0%) Frame = +1 Query: 145 LHGHEDDVRGICICGDVGVATS-SRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVW 321 L GH V + I D G+ S S D T++ W+ + L S+ +GP+ Sbjct: 388 LRGHTGPVNSVRIIRDRGLVLSGSDDSTIKIWSLET--------NTCLHTFSAHIGPV-- 437 Query: 322 APPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAID 465 S + + S +D + W++ + T+ GH V +A D Sbjct: 438 --QSLALADSRLFSCSLDGTIKQWDIEKKKCVHTLFGHIEGVWEIAAD 483
>GBLP_CHLRE (P25387) Guanine nucleotide-binding protein beta subunit-like| protein Length = 318 Score = 52.0 bits (123), Expect = 9e-07 Identities = 41/126 (32%), Positives = 54/126 (42%), Gaps = 4/126 (3%) Frame = +1 Query: 133 LSAQLHGHEDDVRGICICGDVGVAT---SSRDKTVRFWTQHPEKKREYVLSKTLVGHSSF 303 L A L GH + V I D T +SRDK+V W + K L GHS F Sbjct: 7 LRATLKGHTNWVTAIATPLDPSSNTLLSASRDKSVLVWELERSESNYGYARKALRGHSHF 66 Query: 304 VGPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAID-DNGDI 480 V +V + ++G D + LW+L+TG GHT V +A DN I Sbjct: 67 VQDVVISSDGQ-----FCLTGSWDGTLRLWDLNTGTTTRRFVGHTKDVLSVAFSVDNRQI 121 Query: 481 ISSSMD 498 +S S D Sbjct: 122 VSGSRD 127 Score = 50.1 bits (118), Expect = 3e-06 Identities = 33/114 (28%), Positives = 55/114 (48%), Gaps = 1/114 (0%) Frame = +1 Query: 151 GHEDDVRGICICGDVG-VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAP 327 GH DV + D + + SRDKT++ W E K Y + + GH+ +V + ++P Sbjct: 104 GHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLGECK--YTIGEP-EGHTEWVSCVRFSP 160 Query: 328 PSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISS 489 + IVSGG D V +WNL ++ + GH V + + +G + +S Sbjct: 161 MTTN---PIIVSGGWDKMVKVWNLTNCKLKNNLVGHHGYVNTVTVSPDGSLCAS 211
>WDR5_MOUSE (P61965) WD-repeat protein 5 (BMP2-induced 3-kb gene protein)| (WD-repeat protein BIG-3) Length = 334 Score = 51.6 bits (122), Expect = 1e-06 Identities = 35/117 (29%), Positives = 57/117 (48%), Gaps = 1/117 (0%) Frame = +1 Query: 145 LHGHEDDVRGICICGDVGVATS-SRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVW 321 + GH+ + + D + S S DKT++ W K KTL GHS++V + Sbjct: 83 ISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGK-----CLKTLKGHSNYVFCCNF 137 Query: 322 APPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSS 492 P S+ IVSG D V +W++ TG+ T+ H+ V+ + + +G +I SS Sbjct: 138 NPQSN-----LIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSS 189 Score = 39.3 bits (90), Expect = 0.006 Identities = 19/46 (41%), Positives = 26/46 (56%) Frame = +1 Query: 355 IVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSS 492 IVSG D V +WNL T E+ ++GHT V A +II+S+ Sbjct: 274 IVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASA 319 Score = 37.0 bits (84), Expect = 0.030 Identities = 19/81 (23%), Positives = 38/81 (46%) Frame = +1 Query: 256 KREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGH 435 K Y L TL GH+ V + ++P + + S D + +W + G+ T+ GH Sbjct: 32 KPNYALKFTLAGHTKAVSSVKFSPNGEW-----LASSSADKLIKIWGAYDGKFEKTISGH 86 Query: 436 TSQVTGLAIDDNGDIISSSMD 498 ++ +A + +++ S+ D Sbjct: 87 KLGISDVAWSSDSNLLVSASD 107
>WDR5_HUMAN (P61964) WD-repeat protein 5 (BMP2-induced 3-kb gene protein)| Length = 334 Score = 51.6 bits (122), Expect = 1e-06 Identities = 35/117 (29%), Positives = 57/117 (48%), Gaps = 1/117 (0%) Frame = +1 Query: 145 LHGHEDDVRGICICGDVGVATS-SRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVW 321 + GH+ + + D + S S DKT++ W K KTL GHS++V + Sbjct: 83 ISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGK-----CLKTLKGHSNYVFCCNF 137 Query: 322 APPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSS 492 P S+ IVSG D V +W++ TG+ T+ H+ V+ + + +G +I SS Sbjct: 138 NPQSN-----LIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSS 189 Score = 39.3 bits (90), Expect = 0.006 Identities = 19/46 (41%), Positives = 26/46 (56%) Frame = +1 Query: 355 IVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSS 492 IVSG D V +WNL T E+ ++GHT V A +II+S+ Sbjct: 274 IVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASA 319 Score = 37.0 bits (84), Expect = 0.030 Identities = 19/81 (23%), Positives = 38/81 (46%) Frame = +1 Query: 256 KREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGH 435 K Y L TL GH+ V + ++P + + S D + +W + G+ T+ GH Sbjct: 32 KPNYALKFTLAGHTKAVSSVKFSPNGEW-----LASSSADKLIKIWGAYDGKFEKTISGH 86 Query: 436 TSQVTGLAIDDNGDIISSSMD 498 ++ +A + +++ S+ D Sbjct: 87 KLGISDVAWSSDSNLLVSASD 107
>UTP13_YEAST (Q05946) U3 small nucleolar RNA-associated protein 13 (U3| snoRNA-associated protein 13) Length = 817 Score = 51.6 bits (122), Expect = 1e-06 Identities = 35/121 (28%), Positives = 62/121 (51%), Gaps = 1/121 (0%) Frame = +1 Query: 133 LSAQLHGHEDDVRGICICG-DVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVG 309 L A L H+ + + C D +ATSS DKTV+ W+ + + KTL GH++ V Sbjct: 525 LEATLANHKRGLWDVSFCQYDKLLATSSGDKTVKIWSLDT-----FSVMKTLEGHTNAVQ 579 Query: 310 PMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISS 489 + + ++S G D + +W+ +GE T+ GH +++ L+ ++GD+I S Sbjct: 580 RCSFINKQKQ-----LISCGADGLIKIWDCSSGECLKTLDGHNNRLWALSTMNDGDMIVS 634 Query: 490 S 492 + Sbjct: 635 A 635
>LIS1_CAEEL (Q9NDC9) Lissencephaly-1 homolog (Pronuclear migration abnormal| protein 1) Length = 404 Score = 51.6 bits (122), Expect = 1e-06 Identities = 42/127 (33%), Positives = 59/127 (46%), Gaps = 11/127 (8%) Frame = +1 Query: 151 GHEDDVRGICICGDVGV-ATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAP 327 GH D VR I I D + A++S D+TV W+ K + VL H V + WAP Sbjct: 231 GHNDWVRMIRISNDGTLFASASLDQTVTVWS-FATKSAKLVLRD----HEHAVECVEWAP 285 Query: 328 PS------DRFPEG----AIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGD 477 + + PEG + SG D + WN++TG+V T+ H + V GLA G Sbjct: 286 DTAYTNVTGQQPEGNSTHILFSGSRDRSIKAWNINTGDVLFTLLAHENWVRGLAFHPKGK 345 Query: 478 IISSSMD 498 + S D Sbjct: 346 YLISVAD 352 Score = 45.8 bits (107), Expect = 6e-05 Identities = 31/121 (25%), Positives = 53/121 (43%), Gaps = 1/121 (0%) Frame = +1 Query: 133 LSAQLHGHEDDVRGICI-CGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVG 309 L L GH D V I I + + S D +++ W + + Y K+L GH V Sbjct: 140 LERTLKGHTDAVNDIAIDAAGKQLVSCSSDLSIKLW----DFGQTYDCLKSLKGHEHTVS 195 Query: 310 PMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISS 489 + + P D ++S D + W++ TG T +GH V + I ++G + +S Sbjct: 196 SVTFLPTGD-----FVLSASRDHTIKQWDISTGYCVYTFRGHNDWVRMIRISNDGTLFAS 250 Query: 490 S 492 + Sbjct: 251 A 251 Score = 37.4 bits (85), Expect = 0.023 Identities = 17/43 (39%), Positives = 26/43 (60%), Gaps = 1/43 (2%) Frame = +1 Query: 373 DTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNG-DIISSSMD 498 D + +W+ TG++ T+KGHT V +AID G ++S S D Sbjct: 127 DATIKVWDYETGQLERTLKGHTDAVNDIAIDAAGKQLVSCSSD 169
>GBLP_LEIMA (Q25306) Guanine nucleotide-binding protein beta subunit-like| protein (Antigen LACK) Length = 312 Score = 51.6 bits (122), Expect = 1e-06 Identities = 29/113 (25%), Positives = 55/113 (48%), Gaps = 1/113 (0%) Frame = +1 Query: 154 HEDDVRGICICGDVGVATSS-RDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPP 330 H DV + D + S+ RD +R W E E++ GH +V + ++P Sbjct: 106 HTKDVLAVAFSPDDRLIVSAGRDNVIRVWNVAGECMHEFLRD----GHEDWVSSICFSPS 161 Query: 331 SDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISS 489 + +VSG D + +WN++ G+ T+KGH++ V+ + + +G + +S Sbjct: 162 LEH---PIVVSGSWDNTIKVWNVNGGKCERTLKGHSNYVSTVTVSPDGSLCAS 211 Score = 48.1 bits (113), Expect = 1e-05 Identities = 32/91 (35%), Positives = 46/91 (50%), Gaps = 4/91 (4%) Frame = +1 Query: 151 GHEDDVRGICICGDVG---VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVW 321 GHED V IC + V + S D T++ W + K +TL GHS++V + Sbjct: 148 GHEDWVSSICFSPSLEHPIVVSGSWDNTIKVWNVNGGK-----CERTLKGHSNYVSTVTV 202 Query: 322 APPSDRFPEGAI-VSGGMDTQVLLWNLHTGE 411 +P +G++ SGG D LLW+L TGE Sbjct: 203 SP------DGSLCASGGKDGAALLWDLSTGE 227 Score = 38.5 bits (88), Expect = 0.010 Identities = 32/124 (25%), Positives = 53/124 (42%), Gaps = 8/124 (6%) Frame = +1 Query: 145 LHGHEDDVRGICICGDVG----VATSSRDKTVRFWTQHPEKKR---EYVL-SKTLVGHSS 300 L GH V + G V ++SRD TV W +P++ +Y L + L GH+ Sbjct: 7 LKGHRGWVTSLACPQQAGSYIKVVSTSRDGTVISWKANPDRHSVDSDYGLPNHRLEGHTG 66 Query: 301 FVGPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDI 480 FV + A +D ++ D + +W+L G+ HT V +A + + Sbjct: 67 FVSCVSLAHATDY-----ALTASWDRSIRMWDLRNGQCQRKFLKHTKDVLAVAFSPDDRL 121 Query: 481 ISSS 492 I S+ Sbjct: 122 IVSA 125
>GBLP_LEIIN (P62884) Guanine nucleotide-binding protein beta subunit-like| protein (Antigen LACK) (LiP36) (p36Li) Length = 312 Score = 51.6 bits (122), Expect = 1e-06 Identities = 29/113 (25%), Positives = 55/113 (48%), Gaps = 1/113 (0%) Frame = +1 Query: 154 HEDDVRGICICGDVGVATSS-RDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPP 330 H DV + D + S+ RD +R W E E++ GH +V + ++P Sbjct: 106 HTKDVLAVAFSPDDRLIVSAGRDNVIRVWNVAGECMHEFLRD----GHEDWVSSICFSPS 161 Query: 331 SDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISS 489 + +VSG D + +WN++ G+ T+KGH++ V+ + + +G + +S Sbjct: 162 LEH---PIVVSGSWDNTIKVWNVNGGKCERTLKGHSNYVSTVTVSPDGSLCAS 211 Score = 48.1 bits (113), Expect = 1e-05 Identities = 32/91 (35%), Positives = 46/91 (50%), Gaps = 4/91 (4%) Frame = +1 Query: 151 GHEDDVRGICICGDVG---VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVW 321 GHED V IC + V + S D T++ W + K +TL GHS++V + Sbjct: 148 GHEDWVSSICFSPSLEHPIVVSGSWDNTIKVWNVNGGK-----CERTLKGHSNYVSTVTV 202 Query: 322 APPSDRFPEGAI-VSGGMDTQVLLWNLHTGE 411 +P +G++ SGG D LLW+L TGE Sbjct: 203 SP------DGSLCASGGKDGAALLWDLSTGE 227 Score = 38.1 bits (87), Expect = 0.013 Identities = 32/124 (25%), Positives = 52/124 (41%), Gaps = 8/124 (6%) Frame = +1 Query: 145 LHGHEDDVRGICICGDVG----VATSSRDKTVRFWTQHPEKKR---EYVL-SKTLVGHSS 300 L GH V + G V ++SRD T W +P++ +Y L S L GH+ Sbjct: 7 LKGHRGWVTSLACPQQAGSYIKVVSTSRDGTAISWKANPDRHSVDSDYGLPSHRLEGHTG 66 Query: 301 FVGPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDI 480 FV + A +D ++ D + +W+L G+ HT V +A + + Sbjct: 67 FVSCVSLAHATDY-----ALTASWDRSIRMWDLRNGQCQRKFLKHTKDVLAVAFSPDDRL 121 Query: 481 ISSS 492 I S+ Sbjct: 122 IVSA 125
>GBLP_LEICH (P62883) Guanine nucleotide-binding protein beta subunit-like| protein (Antigen LACK) Length = 312 Score = 51.6 bits (122), Expect = 1e-06 Identities = 29/113 (25%), Positives = 55/113 (48%), Gaps = 1/113 (0%) Frame = +1 Query: 154 HEDDVRGICICGDVGVATSS-RDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPP 330 H DV + D + S+ RD +R W E E++ GH +V + ++P Sbjct: 106 HTKDVLAVAFSPDDRLIVSAGRDNVIRVWNVAGECMHEFLRD----GHEDWVSSICFSPS 161 Query: 331 SDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISS 489 + +VSG D + +WN++ G+ T+KGH++ V+ + + +G + +S Sbjct: 162 LEH---PIVVSGSWDNTIKVWNVNGGKCERTLKGHSNYVSTVTVSPDGSLCAS 211 Score = 48.1 bits (113), Expect = 1e-05 Identities = 32/91 (35%), Positives = 46/91 (50%), Gaps = 4/91 (4%) Frame = +1 Query: 151 GHEDDVRGICICGDVG---VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVW 321 GHED V IC + V + S D T++ W + K +TL GHS++V + Sbjct: 148 GHEDWVSSICFSPSLEHPIVVSGSWDNTIKVWNVNGGK-----CERTLKGHSNYVSTVTV 202 Query: 322 APPSDRFPEGAI-VSGGMDTQVLLWNLHTGE 411 +P +G++ SGG D LLW+L TGE Sbjct: 203 SP------DGSLCASGGKDGAALLWDLSTGE 227 Score = 38.1 bits (87), Expect = 0.013 Identities = 32/124 (25%), Positives = 52/124 (41%), Gaps = 8/124 (6%) Frame = +1 Query: 145 LHGHEDDVRGICICGDVG----VATSSRDKTVRFWTQHPEKKR---EYVL-SKTLVGHSS 300 L GH V + G V ++SRD T W +P++ +Y L S L GH+ Sbjct: 7 LKGHRGWVTSLACPQQAGSYIKVVSTSRDGTAISWKANPDRHSVDSDYGLPSHRLEGHTG 66 Query: 301 FVGPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDI 480 FV + A +D ++ D + +W+L G+ HT V +A + + Sbjct: 67 FVSCVSLAHATDY-----ALTASWDRSIRMWDLRNGQCQRKFLKHTKDVLAVAFSPDDRL 121 Query: 481 ISSS 492 I S+ Sbjct: 122 IVSA 125
>HETE1_PODAN (Q00808) Vegetatible incompatibility protein HET-E-1| Length = 1356 Score = 51.6 bits (122), Expect = 1e-06 Identities = 32/119 (26%), Positives = 54/119 (45%), Gaps = 1/119 (0%) Frame = +1 Query: 145 LHGHEDDVRGICICGD-VGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVW 321 L GH V + D VA+ S DKT++ W ++TL GH V + + Sbjct: 837 LEGHGSSVLSVAFSADGQRVASGSDDKTIKIWDTASGTG-----TQTLEGHGGSVWSVAF 891 Query: 322 APPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSSMD 498 +P +R + SG D + +W+ +G T++GH +V +A +G ++S D Sbjct: 892 SPDRER-----VASGSDDKTIKIWDAASGTCTQTLEGHGGRVQSVAFSPDGQRVASGSD 945 Score = 50.1 bits (118), Expect = 3e-06 Identities = 32/116 (27%), Positives = 53/116 (45%), Gaps = 1/116 (0%) Frame = +1 Query: 145 LHGHEDDVRGICICGD-VGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVW 321 L GH V + D VA+ S DKT++ W ++TL GH +V +V+ Sbjct: 1005 LEGHGGSVWSVAFSPDGQRVASGSDDKTIKIWDT-----ASGTCTQTLEGHGGWVQSVVF 1059 Query: 322 APPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISS 489 +P R + SG D + +W+ +G T++GH V +A +G ++S Sbjct: 1060 SPDGQR-----VASGSDDHTIKIWDAVSGTCTQTLEGHGDSVWSVAFSPDGQRVAS 1110 Score = 49.7 bits (117), Expect = 4e-06 Identities = 31/116 (26%), Positives = 53/116 (45%), Gaps = 1/116 (0%) Frame = +1 Query: 145 LHGHEDDVRGICICGD-VGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVW 321 L GH D V + D VA+ S D T++ W ++TL GH +V + + Sbjct: 1089 LEGHGDSVWSVAFSPDGQRVASGSIDGTIKIWDA-----ASGTCTQTLEGHGGWVHSVAF 1143 Query: 322 APPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISS 489 +P R + SG +D + +W+ +G T++GH V +A +G ++S Sbjct: 1144 SPDGQR-----VASGSIDGTIKIWDAASGTCTQTLEGHGGWVQSVAFSPDGQRVAS 1194 Score = 49.3 bits (116), Expect = 6e-06 Identities = 32/119 (26%), Positives = 53/119 (44%), Gaps = 1/119 (0%) Frame = +1 Query: 145 LHGHEDDVRGICICGD-VGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVW 321 L GH V+ + D VA+ S D T++ W ++TL GH S V + + Sbjct: 921 LEGHGGRVQSVAFSPDGQRVASGSDDHTIKIWDA-----ASGTCTQTLEGHGSSVLSVAF 975 Query: 322 APPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSSMD 498 +P R + SG D + +W+ +G T++GH V +A +G ++S D Sbjct: 976 SPDGQR-----VASGSGDKTIKIWDTASGTCTQTLEGHGGSVWSVAFSPDGQRVASGSD 1029 Score = 48.9 bits (115), Expect = 8e-06 Identities = 31/119 (26%), Positives = 51/119 (42%), Gaps = 1/119 (0%) Frame = +1 Query: 145 LHGHEDDVRGICICGD-VGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVW 321 L GH V + D VA+ S DKT++ W ++TL GH V + + Sbjct: 963 LEGHGSSVLSVAFSPDGQRVASGSGDKTIKIWDT-----ASGTCTQTLEGHGGSVWSVAF 1017 Query: 322 APPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSSMD 498 +P R + SG D + +W+ +G T++GH V + +G ++S D Sbjct: 1018 SPDGQR-----VASGSDDKTIKIWDTASGTCTQTLEGHGGWVQSVVFSPDGQRVASGSD 1071 Score = 46.2 bits (108), Expect = 5e-05 Identities = 30/116 (25%), Positives = 51/116 (43%), Gaps = 1/116 (0%) Frame = +1 Query: 145 LHGHEDDVRGICICGD-VGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVW 321 L GH V + D VA+ S D T++ W ++TL GH +V + + Sbjct: 1131 LEGHGGWVHSVAFSPDGQRVASGSIDGTIKIWDA-----ASGTCTQTLEGHGGWVQSVAF 1185 Query: 322 APPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISS 489 +P R + SG D + +W+ +G T++GH V +A +G ++S Sbjct: 1186 SPDGQR-----VASGSSDKTIKIWDTASGTCTQTLEGHGGWVQSVAFSPDGQRVAS 1236
>GBLP_CHICK (P63247) Guanine nucleotide-binding protein beta subunit 2-like 1| (Guanine nucleotide-binding protein beta subunit-like protein 12.3) (Receptor of activated protein kinase C 1) (RACK1) (Receptor for activated C kinase) Length = 317 Score = 51.2 bits (121), Expect = 2e-06 Identities = 32/101 (31%), Positives = 47/101 (46%), Gaps = 1/101 (0%) Frame = +1 Query: 199 VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDT 378 + ++SRDKT+ W ++ + + L GHS FV +V + +SG D Sbjct: 31 ILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSDGQ-----FALSGSWDG 85 Query: 379 QVLLWNLHTGEVAGTMKGHTSQVTGLAI-DDNGDIISSSMD 498 + LW+L TG GHT V +A DN I+S S D Sbjct: 86 TLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRD 126 Score = 42.7 bits (99), Expect = 5e-04 Identities = 32/114 (28%), Positives = 51/114 (44%), Gaps = 1/114 (0%) Frame = +1 Query: 151 GHEDDVRGICICGDVG-VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAP 327 GH DV + D + + SRDKT++ W K Y + HS +V + ++P Sbjct: 103 GHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCK--YTVQDE--SHSEWVSCVRFSP 158 Query: 328 PSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISS 489 S IVS G D V +WNL ++ GHT + + + +G + +S Sbjct: 159 NSSN---PIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCAS 209
>GBLP_BRARE (O42248) Guanine nucleotide-binding protein beta subunit 2-like 1| (Receptor of activated protein kinase C) (RACK) Length = 317 Score = 51.2 bits (121), Expect = 2e-06 Identities = 32/101 (31%), Positives = 47/101 (46%), Gaps = 1/101 (0%) Frame = +1 Query: 199 VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDT 378 + ++SRDKT+ W ++ + + L GHS FV +V + +SG D Sbjct: 31 ILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSDGQ-----FALSGSWDG 85 Query: 379 QVLLWNLHTGEVAGTMKGHTSQVTGLAID-DNGDIISSSMD 498 + LW+L TG GHT V +A DN I+S S D Sbjct: 86 TLRLWDLTTGTTTRRFVGHTKDVLSVAFSADNRQIVSGSRD 126 Score = 42.7 bits (99), Expect = 5e-04 Identities = 31/114 (27%), Positives = 51/114 (44%), Gaps = 1/114 (0%) Frame = +1 Query: 151 GHEDDVRGICICGDVG-VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAP 327 GH DV + D + + SRDKT++ W K Y + H+ +V + ++P Sbjct: 103 GHTKDVLSVAFSADNRQIVSGSRDKTIKLWNTLGVCK--YTIQDD--SHTEWVSCVRFSP 158 Query: 328 PSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISS 489 S IVS G D V +WNL ++ GHT + + + +G + +S Sbjct: 159 NSSN---PIIVSCGWDKMVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCAS 209
>GBLP_ORYSA (P49027) Guanine nucleotide-binding protein beta subunit-like| protein (GPB-LR) (RWD) Length = 334 Score = 51.2 bits (121), Expect = 2e-06 Identities = 43/134 (32%), Positives = 61/134 (45%), Gaps = 12/134 (8%) Frame = +1 Query: 133 LSAQLHGHEDDVRGIC--ICGDVGVATSSRDKTVRFWT-QHPEKK-------REY-VLSK 279 L+ +HGH D V I I + +SSRDK++ W +P + EY V + Sbjct: 10 LAGVMHGHNDVVTAIATPIDNSPFIVSSSRDKSLLVWDLTNPVQNVGEGAGASEYGVPFR 69 Query: 280 TLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLA 459 L GHS FV +V + +SG D ++ LW+L TG GH V +A Sbjct: 70 RLTGHSHFVQDVVLSSDGQ-----FALSGSWDGELRLWDLSTGVTTRRFVGHDKDVLSVA 124 Query: 460 ID-DNGDIISSSMD 498 DN I+S+S D Sbjct: 125 FSVDNRQIVSASRD 138 Score = 50.1 bits (118), Expect = 3e-06 Identities = 33/117 (28%), Positives = 59/117 (50%), Gaps = 4/117 (3%) Frame = +1 Query: 151 GHEDDVRGICICGDVG-VATSSRDKTVRFWTQHPEKKREYVLSKTL---VGHSSFVGPMV 318 GH+ DV + D + ++SRD+T++ W E K Y + L GH+ +V + Sbjct: 115 GHDKDVLSVAFSVDNRQIVSASRDRTIKLWNTLGECK--YTIGGDLGGGEGHNGWVSCVR 172 Query: 319 WAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISS 489 ++P + + IVSG D V +WNL ++ ++GH V +A+ +G + +S Sbjct: 173 FSPNTF---QPTIVSGSWDRTVKVWNLTNCKLRCNLEGHGGYVNAVAVSPDGSLCAS 226 Score = 30.8 bits (68), Expect = 2.1 Identities = 22/72 (30%), Positives = 34/72 (47%), Gaps = 1/72 (1%) Frame = +1 Query: 199 VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAI-VSGGMD 375 + + S D+TV+ W K R L GH +V + +P +G++ SGG D Sbjct: 182 IVSGSWDRTVKVWNLTNCKLR-----CNLEGHGGYVNAVAVSP------DGSLCASGGKD 230 Query: 376 TQVLLWNLHTGE 411 LLW+L G+ Sbjct: 231 GVTLLWDLAEGK 242
>GBLP_RAT (P63245) Guanine nucleotide-binding protein beta subunit 2-like 1| (Receptor of activated protein kinase C 1) (RACK1) (Receptor for activated C kinase) Length = 316 Score = 51.2 bits (121), Expect = 2e-06 Identities = 32/101 (31%), Positives = 47/101 (46%), Gaps = 1/101 (0%) Frame = +1 Query: 199 VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDT 378 + ++SRDKT+ W ++ + + L GHS FV +V + +SG D Sbjct: 30 ILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSDGQ-----FALSGSWDG 84 Query: 379 QVLLWNLHTGEVAGTMKGHTSQVTGLAI-DDNGDIISSSMD 498 + LW+L TG GHT V +A DN I+S S D Sbjct: 85 TLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRD 125 Score = 42.7 bits (99), Expect = 5e-04 Identities = 32/114 (28%), Positives = 51/114 (44%), Gaps = 1/114 (0%) Frame = +1 Query: 151 GHEDDVRGICICGDVG-VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAP 327 GH DV + D + + SRDKT++ W K Y + HS +V + ++P Sbjct: 102 GHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCK--YTVQDE--SHSEWVSCVRFSP 157 Query: 328 PSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISS 489 S IVS G D V +WNL ++ GHT + + + +G + +S Sbjct: 158 NSSN---PIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCAS 208
>GBLP_PIG (P63246) Guanine nucleotide-binding protein beta subunit 2-like 1| (Receptor of activated protein kinase C 1) (RACK1) (Receptor for activated C kinase) Length = 316 Score = 51.2 bits (121), Expect = 2e-06 Identities = 32/101 (31%), Positives = 47/101 (46%), Gaps = 1/101 (0%) Frame = +1 Query: 199 VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDT 378 + ++SRDKT+ W ++ + + L GHS FV +V + +SG D Sbjct: 30 ILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSDGQ-----FALSGSWDG 84 Query: 379 QVLLWNLHTGEVAGTMKGHTSQVTGLAI-DDNGDIISSSMD 498 + LW+L TG GHT V +A DN I+S S D Sbjct: 85 TLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRD 125 Score = 42.7 bits (99), Expect = 5e-04 Identities = 32/114 (28%), Positives = 51/114 (44%), Gaps = 1/114 (0%) Frame = +1 Query: 151 GHEDDVRGICICGDVG-VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAP 327 GH DV + D + + SRDKT++ W K Y + HS +V + ++P Sbjct: 102 GHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCK--YTVQDE--SHSEWVSCVRFSP 157 Query: 328 PSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISS 489 S IVS G D V +WNL ++ GHT + + + +G + +S Sbjct: 158 NSSN---PIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCAS 208
>GBLP_MOUSE (P68040) Guanine nucleotide-binding protein beta subunit 2-like 1| (Receptor of activated protein kinase C 1) (RACK1) (Receptor for activated C kinase) (p205) (12-3) Length = 316 Score = 51.2 bits (121), Expect = 2e-06 Identities = 32/101 (31%), Positives = 47/101 (46%), Gaps = 1/101 (0%) Frame = +1 Query: 199 VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDT 378 + ++SRDKT+ W ++ + + L GHS FV +V + +SG D Sbjct: 30 ILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSDGQ-----FALSGSWDG 84 Query: 379 QVLLWNLHTGEVAGTMKGHTSQVTGLAI-DDNGDIISSSMD 498 + LW+L TG GHT V +A DN I+S S D Sbjct: 85 TLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRD 125 Score = 42.7 bits (99), Expect = 5e-04 Identities = 32/114 (28%), Positives = 51/114 (44%), Gaps = 1/114 (0%) Frame = +1 Query: 151 GHEDDVRGICICGDVG-VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAP 327 GH DV + D + + SRDKT++ W K Y + HS +V + ++P Sbjct: 102 GHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCK--YTVQDE--SHSEWVSCVRFSP 157 Query: 328 PSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISS 489 S IVS G D V +WNL ++ GHT + + + +G + +S Sbjct: 158 NSSN---PIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCAS 208
>GBLP_MACFA (Q4R7Y4) Guanine nucleotide-binding protein beta subunit 2-like 1| Length = 316 Score = 51.2 bits (121), Expect = 2e-06 Identities = 32/101 (31%), Positives = 47/101 (46%), Gaps = 1/101 (0%) Frame = +1 Query: 199 VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDT 378 + ++SRDKT+ W ++ + + L GHS FV +V + +SG D Sbjct: 30 ILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSDGQ-----FALSGSWDG 84 Query: 379 QVLLWNLHTGEVAGTMKGHTSQVTGLAI-DDNGDIISSSMD 498 + LW+L TG GHT V +A DN I+S S D Sbjct: 85 TLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRD 125 Score = 42.7 bits (99), Expect = 5e-04 Identities = 32/114 (28%), Positives = 51/114 (44%), Gaps = 1/114 (0%) Frame = +1 Query: 151 GHEDDVRGICICGDVG-VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAP 327 GH DV + D + + SRDKT++ W K Y + HS +V + ++P Sbjct: 102 GHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCK--YTVQDE--SHSEWVSCVRFSP 157 Query: 328 PSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISS 489 S IVS G D V +WNL ++ GHT + + + +G + +S Sbjct: 158 NSSN---PIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCAS 208
>GBLP_HUMAN (P63244) Guanine nucleotide-binding protein beta subunit 2-like 1| (Guanine nucleotide-binding protein beta subunit-like protein 12.3) (Receptor of activated protein kinase C 1) (RACK1) (Receptor for activated C kinase) Length = 316 Score = 51.2 bits (121), Expect = 2e-06 Identities = 32/101 (31%), Positives = 47/101 (46%), Gaps = 1/101 (0%) Frame = +1 Query: 199 VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDT 378 + ++SRDKT+ W ++ + + L GHS FV +V + +SG D Sbjct: 30 ILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSDGQ-----FALSGSWDG 84 Query: 379 QVLLWNLHTGEVAGTMKGHTSQVTGLAI-DDNGDIISSSMD 498 + LW+L TG GHT V +A DN I+S S D Sbjct: 85 TLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRD 125 Score = 42.7 bits (99), Expect = 5e-04 Identities = 32/114 (28%), Positives = 51/114 (44%), Gaps = 1/114 (0%) Frame = +1 Query: 151 GHEDDVRGICICGDVG-VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAP 327 GH DV + D + + SRDKT++ W K Y + HS +V + ++P Sbjct: 102 GHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCK--YTVQDE--SHSEWVSCVRFSP 157 Query: 328 PSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISS 489 S IVS G D V +WNL ++ GHT + + + +G + +S Sbjct: 158 NSSN---PIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCAS 208
>GBLP_BOVIN (P63243) Guanine nucleotide-binding protein beta subunit 2-like 1| (Receptor of activated protein kinase C 1) (RACK1) (Receptor for activated C kinase) Length = 316 Score = 51.2 bits (121), Expect = 2e-06 Identities = 32/101 (31%), Positives = 47/101 (46%), Gaps = 1/101 (0%) Frame = +1 Query: 199 VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDT 378 + ++SRDKT+ W ++ + + L GHS FV +V + +SG D Sbjct: 30 ILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSDGQ-----FALSGSWDG 84 Query: 379 QVLLWNLHTGEVAGTMKGHTSQVTGLAI-DDNGDIISSSMD 498 + LW+L TG GHT V +A DN I+S S D Sbjct: 85 TLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRD 125 Score = 42.7 bits (99), Expect = 5e-04 Identities = 32/114 (28%), Positives = 51/114 (44%), Gaps = 1/114 (0%) Frame = +1 Query: 151 GHEDDVRGICICGDVG-VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAP 327 GH DV + D + + SRDKT++ W K Y + HS +V + ++P Sbjct: 102 GHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCK--YTVQDE--SHSEWVSCVRFSP 157 Query: 328 PSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISS 489 S IVS G D V +WNL ++ GHT + + + +G + +S Sbjct: 158 NSSN---PIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCAS 208
>WDS_DROME (Q9V3J8) Protein will die slowly| Length = 361 Score = 51.2 bits (121), Expect = 2e-06 Identities = 35/117 (29%), Positives = 57/117 (48%), Gaps = 1/117 (0%) Frame = +1 Query: 145 LHGHEDDVRGICICGDVGVATS-SRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVW 321 + GH+ + + D + S S DKT++ W K KTL GHS++V + Sbjct: 110 ISGHKLGISDVAWSSDSRLLVSGSDDKTLKVWELSTGKSL-----KTLKGHSNYVFCCNF 164 Query: 322 APPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSS 492 P S+ IVSG D V +W++ TG+ T+ H+ V+ + + +G +I SS Sbjct: 165 NPQSN-----LIVSGSFDESVRIWDVRTGKCLKTLPAHSDPVSAVHFNRDGSLIVSS 216 Score = 38.1 bits (87), Expect = 0.013 Identities = 19/46 (41%), Positives = 26/46 (56%) Frame = +1 Query: 355 IVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSS 492 IVSG D V +WNL + EV ++GHT V A +II+S+ Sbjct: 301 IVSGSEDNMVYIWNLQSKEVVQKLQGHTDTVLCTACHPTENIIASA 346 Score = 35.8 bits (81), Expect = 0.066 Identities = 24/104 (23%), Positives = 41/104 (39%) Frame = +1 Query: 187 GDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSG 366 G G TSS K Y L TL GH+ V + ++P + + S Sbjct: 38 GQPGATTSSNSSASN--KSSLSVKPNYTLKFTLAGHTKAVSAVKFSPNGEW-----LASS 90 Query: 367 GMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSSMD 498 D + +W + G+ T+ GH ++ +A + ++ S D Sbjct: 91 SADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSRLLVSGSD 134
>COR1C_HUMAN (Q9ULV4) Coronin-1C (Coronin-3) (hCRNN4)| Length = 474 Score = 50.8 bits (120), Expect = 2e-06 Identities = 36/120 (30%), Positives = 58/120 (48%), Gaps = 6/120 (5%) Frame = +1 Query: 151 GHEDDVRGICIC--GDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLV---GHSSFVGPM 315 GH V I C D +A+ S D TV W Q PE L++ +V GHS VG + Sbjct: 78 GHTGPVLDIDWCPHNDQVIASGSEDCTVMVW-QIPENGLTLSLTEPVVILEGHSKRVGIV 136 Query: 316 VWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKG-HTSQVTGLAIDDNGDIISSS 492 W P + ++S G D +++WN+ TGE + H+ + ++ + NG +I ++ Sbjct: 137 AWHPTA----RNVLLSAGCDNAIIIWNVGTGEALINLDDMHSDMIYNVSWNRNGSLICTA 192
>PRP46_CRYNE (Q5KDR4) Pre-mRNA-splicing factor PRP46 (Pre-mRNA-processing| protein 46) Length = 473 Score = 50.8 bits (120), Expect = 2e-06 Identities = 37/106 (34%), Positives = 51/106 (48%), Gaps = 1/106 (0%) Frame = +1 Query: 148 HGHEDDVRGICICGDVGV-ATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWA 324 HGH V + + + V T RD +VR W + R + TL GH+S VG + Sbjct: 263 HGHFSGVYSLSVHPTLDVLVTGGRDASVRVWDM---RTRANIF--TLTGHTSTVGDV--- 314 Query: 325 PPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAI 462 D P+ I+SG MD+ V LW+L G+ T+ H V LAI Sbjct: 315 KTQDSDPQ--IISGSMDSTVRLWDLAAGKCMNTLTHHKKSVRALAI 358 Score = 47.0 bits (110), Expect = 3e-05 Identities = 39/129 (30%), Positives = 57/129 (44%), Gaps = 2/129 (1%) Frame = +1 Query: 118 MAAYHLSAQLHGHEDDVRGICICGDVGVATS-SRDKTVRFWTQHPEKKREYVLSKTLVGH 294 +A+ L L GH +RG+ + S + DK V+ W K + + GH Sbjct: 211 LASGELKLSLTGHISTIRGLAVSDRHPYLFSCAEDKMVKCWDLETNK-----VIRHYHGH 265 Query: 295 SSFVGPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNG 474 S V + P D +V+GG D V +W++ T T+ GHTS V + D+ Sbjct: 266 FSGVYSLSVHPTLD-----VLVTGGRDASVRVWDMRTRANIFTLTGHTSTVGDVKTQDSD 320 Query: 475 -DIISSSMD 498 IIS SMD Sbjct: 321 PQIISGSMD 329 Score = 43.5 bits (101), Expect = 3e-04 Identities = 23/74 (31%), Positives = 39/74 (52%) Frame = +1 Query: 247 PEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTM 426 PE E+ L++ + GH +V + P + F GA D + +W+L +GE+ ++ Sbjct: 166 PEYHPEWKLTRVISGHMGWVRAVAMDPGNQWFATGA-----GDRVIKIWDLASGELKLSL 220 Query: 427 KGHTSQVTGLAIDD 468 GH S + GLA+ D Sbjct: 221 TGHISTIRGLAVSD 234
>COR1C_MOUSE (Q9WUM4) Coronin-1C (Coronin-3)| Length = 474 Score = 50.4 bits (119), Expect = 3e-06 Identities = 36/120 (30%), Positives = 57/120 (47%), Gaps = 6/120 (5%) Frame = +1 Query: 151 GHEDDVRGICIC--GDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLV---GHSSFVGPM 315 GH V I C D +A+ S D TV W Q PE L++ +V GHS VG + Sbjct: 78 GHTGPVLDIDWCPHNDQVIASGSEDCTVMVW-QIPENGLTLSLTEPVVILEGHSKRVGIV 136 Query: 316 VWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKG-HTSQVTGLAIDDNGDIISSS 492 W P + ++S G D +++WN+ TGE + H+ + ++ NG +I ++ Sbjct: 137 AWHPTA----RNVLLSAGCDNAIIIWNVGTGEALINLDDMHSDMIYNVSWSRNGSLICTA 192
>GBLP_DROME (O18640) Guanine nucleotide-binding protein beta subunit-like| protein (Receptor of activated protein kinase C homolog) Length = 318 Score = 50.4 bits (119), Expect = 3e-06 Identities = 32/102 (31%), Positives = 49/102 (48%), Gaps = 2/102 (1%) Frame = +1 Query: 199 VATSSRDKTVRFWTQHPEKKREYVL-SKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMD 375 + ++SRDKT+ W ++ Y K L GHS F+ +V + + +SG D Sbjct: 31 IISASRDKTLIVWKLTRDEDTNYGYPQKRLYGHSHFISDVVLSSDGNY-----ALSGSWD 85 Query: 376 TQVLLWNLHTGEVAGTMKGHTSQVTGLAID-DNGDIISSSMD 498 + LW+L G+ +GHT V +A DN I+S S D Sbjct: 86 QTLRLWDLAAGKTTRRFEGHTKDVLSVAFSADNRQIVSGSRD 127 Score = 47.4 bits (111), Expect = 2e-05 Identities = 32/125 (25%), Positives = 57/125 (45%), Gaps = 1/125 (0%) Frame = +1 Query: 118 MAAYHLSAQLHGHEDDVRGICICGDVG-VATSSRDKTVRFWTQHPEKKREYVLSKTLVGH 294 +AA + + GH DV + D + + SRDKT++ W E K + + + GH Sbjct: 93 LAAGKTTRRFEGHTKDVLSVAFSADNRQIVSGSRDKTIKLWNTLAECK--FTIQED--GH 148 Query: 295 SSFVGPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNG 474 + +V + ++P IVS G D V +WNL ++ GH + + + +G Sbjct: 149 TDWVSCVRFSP---NHSNPIIVSCGWDRTVKVWNLANCKLKNNHHGHNGYLNTVTVSPDG 205 Query: 475 DIISS 489 + +S Sbjct: 206 SLCTS 210
>GBLP_BIOGL (Q93134) Guanine nucleotide-binding protein beta subunit 2-like 1| (Receptor of activated protein kinase C) (RACK) Length = 316 Score = 50.4 bits (119), Expect = 3e-06 Identities = 31/101 (30%), Positives = 48/101 (47%), Gaps = 1/101 (0%) Frame = +1 Query: 199 VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDT 378 + ++SRDK++ W ++ V K+L GH FV ++ + +SG D Sbjct: 31 ILSASRDKSLIVWRLTRDESSYGVPQKSLHGHGHFVSDVILSSDGQ-----FALSGSWDH 85 Query: 379 QVLLWNLHTGEVAGTMKGHTSQVTGLAID-DNGDIISSSMD 498 + LW+L TG+ GHT V +A DN I+S S D Sbjct: 86 TLRLWDLSTGQTTRRFVGHTKDVLSVAFSADNRQIVSGSRD 126 Score = 41.6 bits (96), Expect = 0.001 Identities = 30/114 (26%), Positives = 50/114 (43%), Gaps = 1/114 (0%) Frame = +1 Query: 151 GHEDDVRGICICGDVG-VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAP 327 GH DV + D + + SRDKT++ W K Y + H+ + + ++P Sbjct: 103 GHTKDVLSVAFSADNRQIVSGSRDKTIKLWNTLGVCK--YTIQDDC--HTDWTSCVRFSP 158 Query: 328 PSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISS 489 + IVS G D V +WNL ++ GHT V + + +G + +S Sbjct: 159 NTQN---PIIVSSGWDRLVKVWNLTNCKLKTNHYGHTGYVNTVTVSPDGSLCAS 209 Score = 36.6 bits (83), Expect = 0.039 Identities = 24/92 (26%), Positives = 42/92 (45%), Gaps = 1/92 (1%) Frame = +1 Query: 199 VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAI-VSGGMD 375 + +S D+ V+ W K L GH+ +V + +P +G++ SGG D Sbjct: 165 IVSSGWDRLVKVWNLTNCK-----LKTNHYGHTGYVNTVTVSP------DGSLCASGGKD 213 Query: 376 TQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDN 471 +Q +LW+L+ G+ T+ G + L N Sbjct: 214 SQAMLWDLNEGKHLYTLDGAGDTINALCFSPN 245
>TAF5L_MOUSE (Q91WQ5) TAF5-like RNA polymerase II p300/CBP-associated| factor-associated factor 65 kDa subunit 5L (PCAF-associated factor 65 beta) (PAF65-beta) Length = 589 Score = 50.4 bits (119), Expect = 3e-06 Identities = 33/101 (32%), Positives = 50/101 (49%), Gaps = 1/101 (0%) Frame = +1 Query: 199 VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDT 378 +AT S DKTVR W+ + GH V + ++P + S G D Sbjct: 441 LATGSTDKTVRLWSAQQGNS-----VRLFTGHRGPVLSLSFSPNGKY-----LASAGEDQ 490 Query: 379 QVLLWNLHTGEVAGTMKGHTSQVTGLAID-DNGDIISSSMD 498 ++ LW+L +G + ++GHT +T LA D+G I S+SMD Sbjct: 491 RLKLWDLASGTLFKELRGHTDSITSLAFSPDSGLIASASMD 531
>COR2B_HUMAN (Q9UQ03) Coronin-2B (Coronin-like protein C) (ClipinC) (Protein| FC96) Length = 475 Score = 50.1 bits (118), Expect = 3e-06 Identities = 29/101 (28%), Positives = 55/101 (54%), Gaps = 3/101 (2%) Frame = +1 Query: 199 VATSSRDKTVRFWTQHPEKKREYVLSKTLV---GHSSFVGPMVWAPPSDRFPEGAIVSGG 369 +A+ S D +VR W + PE + +++ L+ GHS VG + W P ++ + S G Sbjct: 98 IASCSEDTSVRIW-EIPEGGLKRNMTEALLELHGHSRRVGLVEWHPTTNNI----LFSAG 152 Query: 370 MDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSS 492 D +VL+WNL GE + HT + ++ + +G +++++ Sbjct: 153 YDYKVLIWNLDVGEPVKMIDCHTDVILCMSFNTDGSLLTTT 193
>PRP46_YARLI (Q6C709) Pre-mRNA-splicing factor PRP46 (Pre-mRNA-processing| protein 46) Length = 472 Score = 50.1 bits (118), Expect = 3e-06 Identities = 40/125 (32%), Positives = 57/125 (45%), Gaps = 1/125 (0%) Frame = +1 Query: 121 AAYHLSAQLHGHEDDVRGICICGD-VGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHS 297 A + + + GH+ VR +C+ + AT S DKT++ W K R TL GH Sbjct: 151 APWEIYRVITGHQGWVRSVCVEPENQWFATGSADKTIKIWDLATGKLR-----LTLTGHI 205 Query: 298 SFVGPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGD 477 V + +P R P + SGG D V W+L T +V GH S V L I D Sbjct: 206 MGVRALGVSP---RHPY--MFSGGEDKMVKCWDLETNKVVRHYHGHLSAVYSLDIHPTLD 260 Query: 478 IISSS 492 ++ S+ Sbjct: 261 VLVSA 265
>NLE1_PONPY (Q5RFF8) Notchless homolog 1| Length = 484 Score = 49.7 bits (117), Expect = 4e-06 Identities = 36/116 (31%), Positives = 55/116 (47%), Gaps = 3/116 (2%) Frame = +1 Query: 121 AAYHLSAQLHGHEDDVRGICICGDVG--VATSSRDKTVRFWTQHPEKKREYVLSKTLVGH 294 A ++ L GH + V + G +A+ S D TVRFW E T GH Sbjct: 101 AVTRCTSSLEGHSEAVISVAF-SPTGKYLASGSGDTTVRFWDLSTETPH-----FTCKGH 154 Query: 295 SSFVGPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAG-TMKGHTSQVTGLA 459 +V + W+P + + SG + Q+LLW+ TG+ G T+ GH+ +TGL+ Sbjct: 155 RHWVLSISWSPDGKK-----LASGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLS 205 Score = 41.2 bits (95), Expect = 0.002 Identities = 24/88 (27%), Positives = 40/88 (45%) Frame = +1 Query: 199 VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDT 378 VA+SS+D +VR W + + L GH+ V + W +G + S D Sbjct: 218 VASSSKDGSVRIWDTTAGR-----CERILTGHTQSVTCLRWGG------DGLLYSASQDR 266 Query: 379 QVLLWNLHTGEVAGTMKGHTSQVTGLAI 462 + +W H G + T++GH V +A+ Sbjct: 267 TIKVWRAHDGVLCRTLQGHGHWVNTMAL 294 Score = 39.3 bits (90), Expect = 0.006 Identities = 29/117 (24%), Positives = 57/117 (48%), Gaps = 1/117 (0%) Frame = +1 Query: 142 QLHGHEDDVRGICICGDVG-VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMV 318 ++ GH+ + + D VA++S DK+++ W K Y+ S L GH + V + Sbjct: 366 RMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRTGK---YLAS--LRGHVAAVYQIA 420 Query: 319 WAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISS 489 W+ S +VSG D+ + +W++ ++A + GH +V + +G ++S Sbjct: 421 WSADSR-----LLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWSPDGQRVAS 472 Score = 38.5 bits (88), Expect = 0.010 Identities = 25/105 (23%), Positives = 49/105 (46%), Gaps = 1/105 (0%) Frame = +1 Query: 187 GDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSG 366 G + + S D T+ W+ +KK + GH + + ++++P S + S Sbjct: 339 GPERLVSGSDDFTLFLWSPAEDKKP----LTRMTGHQALINQVLFSPDSR-----IVASA 389 Query: 367 GMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAID-DNGDIISSSMD 498 D + LW+ TG+ +++GH + V +A D+ ++S S D Sbjct: 390 SFDKSIKLWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSD 434 Score = 34.3 bits (77), Expect = 0.19 Identities = 26/86 (30%), Positives = 37/86 (43%), Gaps = 1/86 (1%) Frame = +1 Query: 139 AQLHGHEDDVRGICICGDVGVATS-SRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPM 315 A L GH V I D + S S D T++ W +K L+ L GH+ V + Sbjct: 407 ASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQK-----LAMDLPGHADEVYAV 461 Query: 316 VWAPPSDRFPEGAIVSGGMDTQVLLW 393 W+P R + SGG D + +W Sbjct: 462 DWSPDGQR-----VASGGKDKCLRIW 482 Score = 33.1 bits (74), Expect = 0.43 Identities = 19/57 (33%), Positives = 30/57 (52%) Frame = +1 Query: 145 LHGHEDDVRGICICGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPM 315 L GH V + GD + ++S+D+T++ W H + VL +TL GH +V M Sbjct: 241 LTGHTQSVTCLRWGGDGLLYSASQDRTIKVWRAH-----DGVLCRTLQGHGHWVNTM 292 Score = 32.0 bits (71), Expect = 0.95 Identities = 21/72 (29%), Positives = 33/72 (45%) Frame = +1 Query: 274 SKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTG 453 + +L GHS V + ++P + SG DT V W+L T T KGH V Sbjct: 106 TSSLEGHSEAVISVAFSPTGKY-----LASGSGDTTVRFWDLSTETPHFTCKGHRHWVLS 160 Query: 454 LAIDDNGDIISS 489 ++ +G ++S Sbjct: 161 ISWSPDGKKLAS 172
>NLE1_HUMAN (Q9NVX2) Notchless homolog 1| Length = 484 Score = 49.7 bits (117), Expect = 4e-06 Identities = 36/116 (31%), Positives = 55/116 (47%), Gaps = 3/116 (2%) Frame = +1 Query: 121 AAYHLSAQLHGHEDDVRGICICGDVG--VATSSRDKTVRFWTQHPEKKREYVLSKTLVGH 294 A ++ L GH + V + G +A+ S D TVRFW E T GH Sbjct: 101 AVTRCTSSLEGHSEAVISVAF-SPTGKYLASGSGDTTVRFWDLSTETPH-----FTCKGH 154 Query: 295 SSFVGPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAG-TMKGHTSQVTGLA 459 +V + W+P + + SG + Q+LLW+ TG+ G T+ GH+ +TGL+ Sbjct: 155 RHWVLSISWSPDGKK-----LASGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLS 205 Score = 41.2 bits (95), Expect = 0.002 Identities = 24/88 (27%), Positives = 40/88 (45%) Frame = +1 Query: 199 VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDT 378 VA+SS+D +VR W + + L GH+ V + W +G + S D Sbjct: 218 VASSSKDGSVRIWDTTAGR-----CERILTGHTQSVTCLRWGG------DGLLYSASQDR 266 Query: 379 QVLLWNLHTGEVAGTMKGHTSQVTGLAI 462 + +W H G + T++GH V +A+ Sbjct: 267 TIKVWRAHDGVLCRTLQGHGHWVNTMAL 294 Score = 39.3 bits (90), Expect = 0.006 Identities = 29/117 (24%), Positives = 57/117 (48%), Gaps = 1/117 (0%) Frame = +1 Query: 142 QLHGHEDDVRGICICGDVG-VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMV 318 ++ GH+ + + D VA++S DK+++ W K Y+ S L GH + V + Sbjct: 366 RMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRTGK---YLAS--LRGHVAAVYQIA 420 Query: 319 WAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISS 489 W+ S +VSG D+ + +W++ ++A + GH +V + +G ++S Sbjct: 421 WSADSR-----LLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWSPDGQRVAS 472 Score = 38.5 bits (88), Expect = 0.010 Identities = 25/105 (23%), Positives = 49/105 (46%), Gaps = 1/105 (0%) Frame = +1 Query: 187 GDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSG 366 G + + S D T+ W+ +KK + GH + + ++++P S + S Sbjct: 339 GPERLVSGSDDFTLFLWSPAEDKKP----LTRMTGHQALINQVLFSPDSR-----IVASA 389 Query: 367 GMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAID-DNGDIISSSMD 498 D + LW+ TG+ +++GH + V +A D+ ++S S D Sbjct: 390 SFDKSIKLWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSD 434 Score = 34.3 bits (77), Expect = 0.19 Identities = 26/86 (30%), Positives = 37/86 (43%), Gaps = 1/86 (1%) Frame = +1 Query: 139 AQLHGHEDDVRGICICGDVGVATS-SRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPM 315 A L GH V I D + S S D T++ W +K L+ L GH+ V + Sbjct: 407 ASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQK-----LAMDLPGHADEVYAV 461 Query: 316 VWAPPSDRFPEGAIVSGGMDTQVLLW 393 W+P R + SGG D + +W Sbjct: 462 DWSPDGQR-----VASGGKDKCLRIW 482 Score = 33.1 bits (74), Expect = 0.43 Identities = 19/57 (33%), Positives = 30/57 (52%) Frame = +1 Query: 145 LHGHEDDVRGICICGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPM 315 L GH V + GD + ++S+D+T++ W H + VL +TL GH +V M Sbjct: 241 LTGHTQSVTCLRWGGDGLLYSASQDRTIKVWRAH-----DGVLCRTLQGHGHWVNTM 292 Score = 32.0 bits (71), Expect = 0.95 Identities = 21/72 (29%), Positives = 33/72 (45%) Frame = +1 Query: 274 SKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTG 453 + +L GHS V + ++P + SG DT V W+L T T KGH V Sbjct: 106 TSSLEGHSEAVISVAFSPTGKY-----LASGSGDTTVRFWDLSTETPHFTCKGHRHWVLS 160 Query: 454 LAIDDNGDIISS 489 ++ +G ++S Sbjct: 161 ISWSPDGKKLAS 172
>GBLP_DICDI (P46800) Guanine nucleotide-binding protein beta subunit-like| protein Length = 329 Score = 49.7 bits (117), Expect = 4e-06 Identities = 40/122 (32%), Positives = 54/122 (44%), Gaps = 4/122 (3%) Frame = +1 Query: 145 LHGHEDDVRGICICGDVG--VATSSRDKTVRFWTQHP-EKKREYVLSKTLVGHSSFVGPM 315 L GH V I + + + +SSRDKTV W P + ++L GHS FV + Sbjct: 17 LVGHNGFVTSIAVSPENPDTIISSSRDKTVMVWQLTPTDATSPGKAHRSLKGHSHFVQDV 76 Query: 316 VWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAI-DDNGDIISSS 492 V + +SG D + LW++ G KGHT V +A DN IIS S Sbjct: 77 VISHDGQ-----FALSGSWDNTLRLWDITKGVSTRLFKGHTQDVMSVAFSSDNRQIISGS 131 Query: 493 MD 498 D Sbjct: 132 RD 133 Score = 43.1 bits (100), Expect = 4e-04 Identities = 32/117 (27%), Positives = 53/117 (45%), Gaps = 4/117 (3%) Frame = +1 Query: 151 GHEDDVRGICICGDVG-VATSSRDKTVRFWTQHPEKKREYVLSKTLVG---HSSFVGPMV 318 GH DV + D + + SRD T++ W E K TL G H +V + Sbjct: 110 GHTQDVMSVAFSSDNRQIISGSRDATIKVWNTLGECKF------TLEGPEAHQDWVSCIR 163 Query: 319 WAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISS 489 ++P + IVSG D +V +W++ + + T+ HT V + I +G + +S Sbjct: 164 FSPNTP-----TIVSGSWDNKVKIWDIKSFKCNHTLTDHTGYVNTVTISPDGSLCAS 215 Score = 33.1 bits (74), Expect = 0.43 Identities = 24/101 (23%), Positives = 46/101 (45%), Gaps = 1/101 (0%) Frame = +1 Query: 199 VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAI-VSGGMD 375 + + S D V+ W + + + TL H+ +V + +P +G++ SGG D Sbjct: 171 IVSGSWDNKVKIWDI-----KSFKCNHTLTDHTGYVNTVTISP------DGSLCASGGKD 219 Query: 376 TQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSSMD 498 T LW L +G+ ++ + + LA N +S++ D Sbjct: 220 TFACLWELSSGKPLYKLEARNT-INALAFSPNKYWLSAATD 259
>TAF5L_HUMAN (O75529) TAF5-like RNA polymerase II p300/CBP-associated| factor-associated factor 65 kDa subunit 5L (PCAF-associated factor 65 beta) (PAF65-beta) Length = 589 Score = 49.7 bits (117), Expect = 4e-06 Identities = 32/101 (31%), Positives = 49/101 (48%), Gaps = 1/101 (0%) Frame = +1 Query: 199 VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDT 378 +AT S DKTVR W+ + GH V + ++P + S G D Sbjct: 441 LATGSTDKTVRLWSAQQGNS-----VRLFTGHRGPVLSLAFSPNGKY-----LASAGEDQ 490 Query: 379 QVLLWNLHTGEVAGTMKGHTSQVTGLAID-DNGDIISSSMD 498 ++ LW+L +G + ++GHT +T L D+G I S+SMD Sbjct: 491 RLKLWDLASGTLYKELRGHTDNITSLTFSPDSGLIASASMD 531
>GBLP_ORENI (O42249) Guanine nucleotide-binding protein beta subunit 2-like 1| (Receptor of activated protein kinase C) (RACK) Length = 317 Score = 49.7 bits (117), Expect = 4e-06 Identities = 31/101 (30%), Positives = 48/101 (47%), Gaps = 1/101 (0%) Frame = +1 Query: 199 VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDT 378 + ++SRDK++ W ++ + ++L GHS FV +V + +SG D Sbjct: 31 ILSASRDKSIIMWKLTRDETNYGIPQRSLKGHSHFVSDVVISSDGQ-----FALSGAWDG 85 Query: 379 QVLLWNLHTGEVAGTMKGHTSQVTGLAID-DNGDIISSSMD 498 + LW+L TG GHT V +A DN I+S S D Sbjct: 86 TLRLWDLTTGLTTRRFVGHTKDVLSVAFSADNRQIVSGSRD 126 Score = 45.1 bits (105), Expect = 1e-04 Identities = 32/114 (28%), Positives = 52/114 (45%), Gaps = 1/114 (0%) Frame = +1 Query: 151 GHEDDVRGICICGDVG-VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAP 327 GH DV + D + + SRDKT++ W K Y + GH+ +V + ++P Sbjct: 103 GHTKDVLSVAFSADNRQIVSGSRDKTIKLWNTLGVCK--YTIQDE--GHTEWVSCVRFSP 158 Query: 328 PSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISS 489 S IVS G D V +WNL ++ GHT + + + +G + +S Sbjct: 159 NSSN---PIIVSCGWDKMVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCAS 209
>DOA1_YEAST (P36037) Protein DOA1| Length = 715 Score = 49.3 bits (116), Expect = 6e-06 Identities = 40/127 (31%), Positives = 57/127 (44%), Gaps = 3/127 (2%) Frame = +1 Query: 127 YHLSAQLHGHEDDVRGICICGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFV 306 Y LSA L GH+ DVR + D VA+ SRD TVR W+ K + L + F+ Sbjct: 3 YQLSATLKGHDQDVRDVVAVDDSKVASVSRDGTVRLWS-----KDDQWLGTVVYTGQGFL 57 Query: 307 GPMVWAPPSDRFPEGAIVSGGMDTQ---VLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGD 477 + + + ++ GG DT V L+ + T+ GH V L+ D G Sbjct: 58 NSVCYDSEKE-----LLLFGGKDTMINGVPLFATSGEDPLYTLIGHQGNVCSLSFQD-GV 111 Query: 478 IISSSMD 498 +IS S D Sbjct: 112 VISGSWD 118 Score = 44.3 bits (103), Expect = 2e-04 Identities = 29/98 (29%), Positives = 45/98 (45%) Frame = +1 Query: 205 TSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDTQV 384 T+S DKT++ W K + +V H + V +G +S D + Sbjct: 155 TASADKTIKLWQNDKVIKTFSGIHNDVVRHLAVVD------------DGHFISCSNDGLI 202 Query: 385 LLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSSMD 498 L ++HTG+V T +GH S V + + NGDI+S D Sbjct: 203 KLVDMHTGDVLRTYEGHESFVYCIKLLPNGDIVSCGED 240 Score = 38.9 bits (89), Expect = 0.008 Identities = 31/115 (26%), Positives = 45/115 (39%) Frame = +1 Query: 154 HEDDVRGICICGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPS 333 H D VR + + D + S D ++ H + +T GH SFV + Sbjct: 178 HNDVVRHLAVVDDGHFISCSNDGLIKLVDMHTGD-----VLRTYEGHESFVYCI------ 226 Query: 334 DRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSSMD 498 P G IVS G D V +W+ G + + + + NGDII S D Sbjct: 227 KLLPNGDIVSCGEDRTVRIWSKENGSLKQVITLPAISIWSVDCMSNGDIIVGSSD 281
>Y1491_SYNY3 (P74598) Hypothetical WD-repeat protein sll1491| Length = 348 Score = 49.3 bits (116), Expect = 6e-06 Identities = 33/112 (29%), Positives = 52/112 (46%), Gaps = 2/112 (1%) Frame = +1 Query: 145 LHGHEDDVRGICIC--GDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMV 318 L GH D V G+ G+ V+ S D+T+R W ++ L +TL + +V Sbjct: 140 LVGHTDKVSGVAFSPDGETIVSVSGGDRTIRIW-----ERASGNLIQTLADNLGPTTSVV 194 Query: 319 WAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNG 474 + P +F GAI G D + W+ +T E+ GT + GLA+ +G Sbjct: 195 FTPDGSQFITGAI---GQDRTIKFWDANTFELLGTSPQQPGFINGLAVTPDG 243
>NLE1_MOUSE (Q8VEJ4) Notchless homolog 1| Length = 484 Score = 49.3 bits (116), Expect = 6e-06 Identities = 36/116 (31%), Positives = 55/116 (47%), Gaps = 3/116 (2%) Frame = +1 Query: 121 AAYHLSAQLHGHEDDVRGICICGDVG--VATSSRDKTVRFWTQHPEKKREYVLSKTLVGH 294 A ++ L GH + V + G +A+ S D TVRFW E T GH Sbjct: 101 AVTRCTSSLEGHSEAVISVAF-SPTGKYLASGSGDTTVRFWDLSTETPH-----FTCKGH 154 Query: 295 SSFVGPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTG-EVAGTMKGHTSQVTGLA 459 +V + W+P + + SG + Q+LLW+ TG +V T+ GH+ +TGL+ Sbjct: 155 RHWVLSISWSPDGKK-----LASGCKNGQILLWDPSTGLQVGRTLTGHSKWITGLS 205 Score = 41.2 bits (95), Expect = 0.002 Identities = 30/118 (25%), Positives = 58/118 (49%), Gaps = 1/118 (0%) Frame = +1 Query: 139 AQLHGHEDDVRGICICGDVG-VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPM 315 A++ GH+ + + D VA++S DK+++ W K Y+ S L GH + V + Sbjct: 365 ARMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRTGK---YLAS--LRGHVAAVYQI 419 Query: 316 VWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISS 489 W+ S +VSG D+ + +W++ ++A + GH +V + +G ++S Sbjct: 420 AWSADSR-----LLVSGSSDSTLKVWDVKAQKLATDLPGHADEVYAVDWSPDGQRVAS 472 Score = 40.8 bits (94), Expect = 0.002 Identities = 24/88 (27%), Positives = 40/88 (45%) Frame = +1 Query: 199 VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDT 378 VA+SS+D +VR W + + L GH+ V + W +G + S D Sbjct: 218 VASSSKDGSVRVWDTTAGR-----CERILTGHTQSVTCLRWGG------DGLLYSASQDR 266 Query: 379 QVLLWNLHTGEVAGTMKGHTSQVTGLAI 462 + +W H G + T++GH V +A+ Sbjct: 267 TIKVWRAHDGVLCRTLQGHGHWVNTMAL 294 Score = 34.3 bits (77), Expect = 0.19 Identities = 26/86 (30%), Positives = 37/86 (43%), Gaps = 1/86 (1%) Frame = +1 Query: 139 AQLHGHEDDVRGICICGDVGVATS-SRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPM 315 A L GH V I D + S S D T++ W +K L+ L GH+ V + Sbjct: 407 ASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQK-----LATDLPGHADEVYAV 461 Query: 316 VWAPPSDRFPEGAIVSGGMDTQVLLW 393 W+P R + SGG D + +W Sbjct: 462 DWSPDGQR-----VASGGKDKCLRIW 482 Score = 33.1 bits (74), Expect = 0.43 Identities = 19/57 (33%), Positives = 30/57 (52%) Frame = +1 Query: 145 LHGHEDDVRGICICGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPM 315 L GH V + GD + ++S+D+T++ W H + VL +TL GH +V M Sbjct: 241 LTGHTQSVTCLRWGGDGLLYSASQDRTIKVWRAH-----DGVLCRTLQGHGHWVNTM 292 Score = 32.0 bits (71), Expect = 0.95 Identities = 21/72 (29%), Positives = 33/72 (45%) Frame = +1 Query: 274 SKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTG 453 + +L GHS V + ++P + SG DT V W+L T T KGH V Sbjct: 106 TSSLEGHSEAVISVAFSPTGKY-----LASGSGDTTVRFWDLSTETPHFTCKGHRHWVLS 160 Query: 454 LAIDDNGDIISS 489 ++ +G ++S Sbjct: 161 ISWSPDGKKLAS 172
>SCONB_EMENI (Q00659) Sulfur metabolite repression control protein| Length = 678 Score = 48.9 bits (115), Expect = 8e-06 Identities = 31/90 (34%), Positives = 44/90 (48%), Gaps = 1/90 (1%) Frame = +1 Query: 199 VATSSRDKTVRFW-TQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMD 375 +AT S D T++ W T+ E+ R TL GH S + + +F + ++SG MD Sbjct: 362 LATGSYDTTIKIWDTETGEELR------TLRGHESGIRCL-------QFDDTKLISGSMD 408 Query: 376 TQVLLWNLHTGEVAGTMKGHTSQVTGLAID 465 + +WN TGE T GH V GL D Sbjct: 409 RTIKVWNWRTGECISTYTGHRGGVIGLHFD 438 Score = 44.3 bits (103), Expect = 2e-04 Identities = 25/74 (33%), Positives = 39/74 (52%) Frame = +1 Query: 277 KTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGL 456 KT GH++ V + +F + + +G DT + +W+ TGE T++GH S + L Sbjct: 343 KTFKGHTNGVMCL-------QFEDNILATGSYDTTIKIWDTETGEELRTLRGHESGIRCL 395 Query: 457 AIDDNGDIISSSMD 498 DD +IS SMD Sbjct: 396 QFDDT-KLISGSMD 408 Score = 42.4 bits (98), Expect = 7e-04 Identities = 30/101 (29%), Positives = 45/101 (44%) Frame = +1 Query: 199 VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDT 378 + TS+ D T+R W + +T GH V WA +D IVSG D Sbjct: 582 MVTSALDSTIRLWETTTGR-----CLRTFFGHLEGV----WALGADTL---RIVSGAEDR 629 Query: 379 QVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSSMDC 501 + +W+ TG+ T GH+ VT + + D+ + S DC Sbjct: 630 MIKIWDPRTGKCERTFTGHSGPVTCIGLGDS-RFATGSEDC 669 Score = 35.4 bits (80), Expect = 0.086 Identities = 32/99 (32%), Positives = 43/99 (43%) Frame = +1 Query: 151 GHEDDVRGICICGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPP 330 GH V G+ + +A+ S DKTV+ W E K + +L GH+ +V V Sbjct: 427 GHRGGVIGLHFDASI-LASGSVDKTVKIWNF--EDKSTF----SLRGHTDWVNA-VRVDT 478 Query: 331 SDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQV 447 S R + S D V LW+L T T GH QV Sbjct: 479 SSR----TVFSASDDCTVRLWDLDTKTCIRTFHGHVGQV 513
>TUP11_SCHPO (Q09715) Transcriptional repressor tup11| Length = 614 Score = 48.9 bits (115), Expect = 8e-06 Identities = 35/122 (28%), Positives = 55/122 (45%), Gaps = 8/122 (6%) Frame = +1 Query: 133 LSAQLHGHEDDVRGICICGDVGVATS-SRDKTVRFWTQHPEK-------KREYVLSKTLV 288 L +L GH++ V I D + S S DKT++ W + K E + T Sbjct: 476 LVERLEGHKESVYSIAFSPDSSILLSGSLDKTIKVWELQATRSVGLSAIKPEGICKATYT 535 Query: 289 GHSSFVGPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDD 468 GH+ FV + +P S R+ +SG D + W+L TG+ T +GH + V + Sbjct: 536 GHTDFVLSVAVSPDS-RWG----LSGSKDRSMQFWDLQTGQSYLTCQGHKNSVISVCFSP 590 Query: 469 NG 474 +G Sbjct: 591 DG 592 Score = 33.9 bits (76), Expect = 0.25 Identities = 18/50 (36%), Positives = 25/50 (50%), Gaps = 1/50 (2%) Frame = +1 Query: 343 PEGA-IVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISS 489 P+G +V+G D Q+ LW+L T +V GH + L NG I S Sbjct: 370 PDGKYLVTGTEDRQIKLWDLSTQKVRYVFSGHEQDIYSLDFSHNGRFIVS 419 Score = 32.0 bits (71), Expect = 0.95 Identities = 27/96 (28%), Positives = 45/96 (46%) Frame = +1 Query: 199 VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDT 378 + T + D+ ++ W +K R YV S GH + + ++ + RF IVSG D Sbjct: 375 LVTGTEDRQIKLWDLSTQKVR-YVFS----GHEQDIYSLDFSH-NGRF----IVSGSGDR 424 Query: 379 QVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIIS 486 LW++ TG+ ++ VT +AI N I+ Sbjct: 425 TARLWDVETGQCILKLEIENG-VTAIAISPNDQFIA 459
>COR2B_MOUSE (Q8BH44) Coronin-2B| Length = 475 Score = 48.5 bits (114), Expect = 1e-05 Identities = 28/101 (27%), Positives = 55/101 (54%), Gaps = 3/101 (2%) Frame = +1 Query: 199 VATSSRDKTVRFWTQHPEKKREYVLSKTLV---GHSSFVGPMVWAPPSDRFPEGAIVSGG 369 +A+ S D +VR W + P+ + +++ L+ GHS VG + W P ++ + S G Sbjct: 98 IASCSEDTSVRIW-EIPDGGLKRNMTEALLELHGHSRRVGLVEWHPTTNNI----LFSAG 152 Query: 370 MDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSS 492 D +VL+WNL GE + HT + ++ + +G +++++ Sbjct: 153 YDYKVLIWNLDIGEPVKMIDCHTDVILCMSFNTDGSLLTTT 193
>WDR57_HUMAN (Q96DI7) WD-repeat protein 57 (Prp8-binding protein) (hPRP8BP) (U5| snRNP-specific 40 kDa protein) (38 kDa splicing factor) Length = 357 Score = 48.5 bits (114), Expect = 1e-05 Identities = 43/159 (27%), Positives = 63/159 (39%), Gaps = 39/159 (24%) Frame = +1 Query: 139 AQLHGHEDDVRGICICGDVGVATS-SRDKTVRFWTQHPEKKREYVLSKTLVGHSSFV--- 306 A L GH V + D + S S DKTV W ++ K L GH+SFV Sbjct: 103 ATLKGHSGAVMELHYNTDGSMLFSASTDKTVAVWDSETGER-----VKRLKGHTSFVNSC 157 Query: 307 -----GPMVWAPPSD-----------------------------RFPEGAIVSGGMDTQV 384 GP + SD I+SGG+D + Sbjct: 158 YPARRGPQLVCTGSDDGTVKLWDIRKKAAIQTFQNTYQVLAVTFNDTSDQIISGGIDNDI 217 Query: 385 LLWNLHTGEVAGTMKGHTSQVTGLAIDDNGD-IISSSMD 498 +W+L ++ TM+GH VTGL++ G ++S++MD Sbjct: 218 KVWDLRQNKLTYTMRGHADSVTGLSLSSEGSYLLSNAMD 256 Score = 39.3 bits (90), Expect = 0.006 Identities = 30/127 (23%), Positives = 55/127 (43%), Gaps = 5/127 (3%) Frame = +1 Query: 133 LSAQLHGHEDDVRGICICGDVG-VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVG 309 L+ + GH D V G+ + + + +++ D TVR W P +E + +F Sbjct: 227 LTYTMRGHADSVTGLSLSSEGSYLLSNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNFEK 286 Query: 310 PMV---WAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAI-DDNGD 477 ++ W+P + I +G D V +W+ + + + GH + +A D Sbjct: 287 NLLRCSWSPDGSK-----IAAGSADRFVYVWDTTSRRILYKLPGHAGSINEVAFHPDEPI 341 Query: 478 IISSSMD 498 IIS+S D Sbjct: 342 IISASSD 348 Score = 32.0 bits (71), Expect = 0.95 Identities = 17/52 (32%), Positives = 30/52 (57%), Gaps = 2/52 (3%) Frame = +1 Query: 343 PEGA-IVSGGMDTQVLLWNLHTG-EVAGTMKGHTSQVTGLAIDDNGDIISSS 492 P G+ + S G D +LLWN++ + T+KGH+ V L + +G ++ S+ Sbjct: 76 PNGSTLASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYNTDGSMLFSA 127 Score = 31.6 bits (70), Expect = 1.2 Identities = 29/103 (28%), Positives = 43/103 (41%), Gaps = 2/103 (1%) Frame = +1 Query: 145 LHGHEDDVRGICICGDVG--VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMV 318 L GHE +V C G +A++ D+ + W + + TL GHS V + Sbjct: 62 LSGHEGEVY-CCKFHPNGSTLASAGFDRLILLWNVYGDCDNY----ATLKGHSGAVMELH 116 Query: 319 WAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQV 447 + + S D V +W+ TGE +KGHTS V Sbjct: 117 YNTDGSM-----LFSASTDKTVAVWDSETGERVKRLKGHTSFV 154
>TUP12_SCHPO (Q9UUG8) Transcriptional repressor tup12| Length = 586 Score = 48.5 bits (114), Expect = 1e-05 Identities = 34/122 (27%), Positives = 52/122 (42%), Gaps = 8/122 (6%) Frame = +1 Query: 133 LSAQLHGHEDDVRGICICGDVGVATS-SRDKTVRFWTQH------PEKKREYVLSK-TLV 288 L QLHGHE+ V + D S S D T++ W P +E + K T Sbjct: 450 LVEQLHGHEESVYSVAFSPDGKYLVSGSLDNTIKLWELQCVSNVAPSMYKEGGICKQTFT 509 Query: 289 GHSSFVGPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDD 468 GH F+ + +P I+SG D + W+ + T++GH + V +A+ Sbjct: 510 GHKDFILSVTVSPDGKW-----IISGSKDRTIQFWSPDSPHSQLTLQGHNNSVISVAVSP 564 Query: 469 NG 474 NG Sbjct: 565 NG 566 Score = 33.1 bits (74), Expect = 0.43 Identities = 29/120 (24%), Positives = 51/120 (42%), Gaps = 2/120 (1%) Frame = +1 Query: 145 LHGHEDDVRGICICGDVGVATS-SRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVW 321 L GHE ++ + D S S D+TV W +++ L+ H+ V Sbjct: 372 LTGHEQEIYSLDFSKDGKTLVSGSGDRTVCLWDVEAGEQK-------LILHTDDGVTTVM 424 Query: 322 APPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGD-IISSSMD 498 P +F I +G +D + +W +G + + GH V +A +G ++S S+D Sbjct: 425 FSPDGQF----IAAGSLDKVIRIWT-SSGTLVEQLHGHEESVYSVAFSPDGKYLVSGSLD 479 Score = 29.6 bits (65), Expect = 4.7 Identities = 26/100 (26%), Positives = 41/100 (41%) Frame = +1 Query: 199 VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDT 378 +AT D+ +R W +KR Y L L GH + + ++ +VSG D Sbjct: 349 LATGVEDQQIRIWDI--AQKRVYRL---LTGHEQEIYSLDFSKDGK-----TLVSGSGDR 398 Query: 379 QVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSSMD 498 V LW++ GE + T + D I + S+D Sbjct: 399 TVCLWDVEAGEQKLILHTDDGVTTVMFSPDGQFIAAGSLD 438
>WDR57_MOUSE (Q6PE01) WD-repeat protein 57| Length = 358 Score = 48.5 bits (114), Expect = 1e-05 Identities = 43/159 (27%), Positives = 63/159 (39%), Gaps = 39/159 (24%) Frame = +1 Query: 139 AQLHGHEDDVRGICICGDVGVATS-SRDKTVRFWTQHPEKKREYVLSKTLVGHSSFV--- 306 A L GH V + D + S S DKTV W ++ K L GH+SFV Sbjct: 104 ATLKGHSGAVMELHYNTDGSMLFSASTDKTVAVWDSETGER-----VKRLKGHTSFVNSC 158 Query: 307 -----GPMVWAPPSD-----------------------------RFPEGAIVSGGMDTQV 384 GP + SD I+SGG+D + Sbjct: 159 YPARRGPQLVCTGSDDGTVKLWDIRKKAAVQTFQNTYQVLAVTFNDTSDQIISGGIDNDI 218 Query: 385 LLWNLHTGEVAGTMKGHTSQVTGLAIDDNGD-IISSSMD 498 +W+L ++ TM+GH VTGL++ G ++S++MD Sbjct: 219 KVWDLRQNKLTYTMRGHADSVTGLSLSSEGSYLLSNAMD 257 Score = 38.9 bits (89), Expect = 0.008 Identities = 30/127 (23%), Positives = 55/127 (43%), Gaps = 5/127 (3%) Frame = +1 Query: 133 LSAQLHGHEDDVRGICICGDVG-VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVG 309 L+ + GH D V G+ + + + +++ D TVR W P +E + +F Sbjct: 228 LTYTMRGHADSVTGLSLSSEGSYLLSNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNFEK 287 Query: 310 PMV---WAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAI-DDNGD 477 ++ W+P + I +G D V +W+ + V + GH + +A D Sbjct: 288 NLLRCSWSPDGSK-----IAAGSADRFVYVWDTTSRRVLYKLPGHAGSINEVAFHPDEPI 342 Query: 478 IISSSMD 498 I+S+S D Sbjct: 343 ILSASSD 349 Score = 32.0 bits (71), Expect = 0.95 Identities = 17/52 (32%), Positives = 30/52 (57%), Gaps = 2/52 (3%) Frame = +1 Query: 343 PEGA-IVSGGMDTQVLLWNLHTG-EVAGTMKGHTSQVTGLAIDDNGDIISSS 492 P G+ + S G D +LLWN++ + T+KGH+ V L + +G ++ S+ Sbjct: 77 PNGSTLASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYNTDGSMLFSA 128 Score = 31.6 bits (70), Expect = 1.2 Identities = 29/103 (28%), Positives = 43/103 (41%), Gaps = 2/103 (1%) Frame = +1 Query: 145 LHGHEDDVRGICICGDVG--VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMV 318 L GHE +V C G +A++ D+ + W + + TL GHS V + Sbjct: 63 LSGHEGEVY-CCKFHPNGSTLASAGFDRLILLWNVYGDCDNY----ATLKGHSGAVMELH 117 Query: 319 WAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQV 447 + + S D V +W+ TGE +KGHTS V Sbjct: 118 YNTDGSM-----LFSASTDKTVAVWDSETGERVKRLKGHTSFV 155
>CDC4_CANAL (P53699) Cell division control protein 4| Length = 684 Score = 48.5 bits (114), Expect = 1e-05 Identities = 39/123 (31%), Positives = 59/123 (47%) Frame = +1 Query: 130 HLSAQLHGHEDDVRGICICGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVG 309 +L A L GH VR I G++ + + S D TVR W + +VL GH Sbjct: 471 YLIAVLSGHTQSVRSISGYGNI-IISGSYDSTVRVWDLLDDGHCTHVLQ----GHLD--- 522 Query: 310 PMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISS 489 V++ D F SG MD+ + +WN TGE+ + GH S V L + D+ ++S+ Sbjct: 523 -RVYSTAID-FHSKTCFSGSMDSNINVWNFETGELKKVLVGHASLVGLLDLVDD-VLVSA 579 Query: 490 SMD 498 + D Sbjct: 580 AAD 582 Score = 42.7 bits (99), Expect = 5e-04 Identities = 31/108 (28%), Positives = 45/108 (41%), Gaps = 1/108 (0%) Frame = +1 Query: 130 HLSAQLHGHEDDVRGICICGDVGVATS-SRDKTVRFWTQHPEKKREYVLSKTLVGHSSFV 306 H + L GH D V I S S D + W + L K LVGH+S V Sbjct: 512 HCTHVLQGHLDRVYSTAIDFHSKTCFSGSMDSNINVWNFETGE-----LKKVLVGHASLV 566 Query: 307 GPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVT 450 G + + +VS D + +W+ TGE+ +KGH + +T Sbjct: 567 GLL-------DLVDDVLVSAAADATLRIWDAKTGELRSKLKGHGAAIT 607 Score = 39.3 bits (90), Expect = 0.006 Identities = 30/104 (28%), Positives = 44/104 (42%) Frame = +1 Query: 151 GHEDDVRGICICGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPP 330 GH + V D V T DK + ++ + L K L GH V WA Sbjct: 322 GHGNKVVTCLQHDDEKVVTGVDDKCISIYSTQTGQ-----LMKVLEGHEGGV----WAL- 371 Query: 331 SDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAI 462 ++ +V+G D V +WN+ TG+ +GHTS + L I Sbjct: 372 --KYTGNTLVTGSTDRTVRVWNMKTGQCTHIFRGHTSTIRCLDI 413
>WDR71_HUMAN (Q9BRP4) WD-repeat protein 71 (Protein G-16)| Length = 392 Score = 48.1 bits (113), Expect = 1e-05 Identities = 39/129 (30%), Positives = 59/129 (45%), Gaps = 2/129 (1%) Frame = +1 Query: 118 MAAYHLSAQLHGHEDDVRGICICGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHS 297 +A Y +++H I G +GV+ SS D T++ W + R + L GH Sbjct: 81 LAPYTTFSRIHTKSITCLDISSRGGLGVS-SSTDGTMKIWQASNGELR-----RVLEGHV 134 Query: 298 SFVGPMVWAPPSDRFPEGAIV-SGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNG 474 V + FP G +V SGGMD Q+ +W+ T KGH + AI D G Sbjct: 135 FDVNCCRF------FPSGLVVLSGGMDAQLKIWSAEDASCVVTFKGHKGGILDTAIVDRG 188 Query: 475 -DIISSSMD 498 +++S+S D Sbjct: 189 RNVVSASRD 197
>YZLL_CAEEL (Q93847) Hypothetical WD-repeat protein K04G11.4| Length = 395 Score = 47.8 bits (112), Expect = 2e-05 Identities = 35/129 (27%), Positives = 62/129 (48%), Gaps = 2/129 (1%) Frame = +1 Query: 109 APLMAAYHLSAQL-HGHEDDVRGICICGDVG-VATSSRDKTVRFWTQHPEKKREYVLSKT 282 A L Y L A++ + H+ + GI D + + S D +++ W + ++V KT Sbjct: 90 ANLWPTYKLVAEIPNAHKKSISGIKFSPDGRYMGSGSADCSIKIW------RMDFVYEKT 143 Query: 283 LVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAI 462 L+GH + W+ S IVS D V ++++ +G T+KGHT+ V Sbjct: 144 LMGHRLGINEFSWSSDSK-----LIVSCSDDKLVKVFDVSSGRCVKTLKGHTNYVFCCCF 198 Query: 463 DDNGDIISS 489 + +G +I+S Sbjct: 199 NPSGTLIAS 207 Score = 37.4 bits (85), Expect = 0.023 Identities = 39/155 (25%), Positives = 59/155 (38%), Gaps = 41/155 (26%) Frame = +1 Query: 151 GHEDDVRGICICGDVG-VATSSRDKTVRFWT-------------QHP-------EKKREY 267 GHED V +C D +A+ S D VR W +HP +Y Sbjct: 230 GHEDPVSSVCFNRDGAYLASGSYDGIVRIWDSTTGTCVKTLIDEEHPPITHVKFSPNGKY 289 Query: 268 VLSKTL------------------VGH--SSFVGPMVWAPPSDRFPEGAIVSGGMDTQVL 387 +L+ L GH S + ++ ++ IVSG D +V Sbjct: 290 ILASNLNNTLKLWDYQKLRVLKEYTGHENSKYCVAANFSVTGGKW----IVSGSEDHKVY 345 Query: 388 LWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSS 492 +WNL T E+ T+ GH + V +II+S+ Sbjct: 346 IWNLQTREILQTLDGHNTAVMCTDCHPGQNIIASA 380
>CORO6_MOUSE (Q920M5) Coronin-6 (Clipin E)| Length = 471 Score = 47.8 bits (112), Expect = 2e-05 Identities = 35/120 (29%), Positives = 60/120 (50%), Gaps = 6/120 (5%) Frame = +1 Query: 151 GHEDDVRGICIC--GDVGVATSSRDKTVRFWTQHPEKKREYVLSK---TLVGHSSFVGPM 315 GH V I C D +A++S D TV W Q P+ +++ TL GHS VG + Sbjct: 79 GHTGPVLDIDWCPHNDNVIASASDDTTVMVW-QIPDYTPVRNITEPVITLEGHSKRVGIL 137 Query: 316 VWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKG-HTSQVTGLAIDDNGDIISSS 492 W P + ++S G D +++WN+ TGEV ++ H + + + NG +++++ Sbjct: 138 SWHPTA----RNVLLSAGGDNVIIIWNVGTGEVLLSLDDIHPDVIHSVCWNSNGSLLATT 193
>WDR57_PONPY (Q5RF51) WD-repeat protein 57| Length = 357 Score = 47.8 bits (112), Expect = 2e-05 Identities = 36/136 (26%), Positives = 56/136 (41%), Gaps = 38/136 (27%) Frame = +1 Query: 205 TSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFV--------GPMVWAPPSD-------- 336 ++S DKTV W ++ K L GH+SFV GP + SD Sbjct: 126 SASTDKTVAVWDSETGER-----VKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWD 180 Query: 337 ---------------------RFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTG 453 I+SGG+D + +W+L ++ TM+GH VTG Sbjct: 181 IRKKAAIQTFQNTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADSVTG 240 Query: 454 LAIDDNGD-IISSSMD 498 L++ G ++S++MD Sbjct: 241 LSLSSEGSYLLSNAMD 256 Score = 40.4 bits (93), Expect = 0.003 Identities = 30/127 (23%), Positives = 55/127 (43%), Gaps = 5/127 (3%) Frame = +1 Query: 133 LSAQLHGHEDDVRGICICGDVG-VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVG 309 L+ + GH D V G+ + + + +++ D TVR W P +E + +F Sbjct: 227 LTYTMRGHADSVTGLSLSSEGSYLLSNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNFEK 286 Query: 310 PMV---WAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAI-DDNGD 477 ++ W+P + I +G D V +W+ + + + GH + +A D Sbjct: 287 NLLRCSWSPDGSK-----IAAGSADRSVCVWDTTSRRILYKLPGHAGSINEVAFHPDEPI 341 Query: 478 IISSSMD 498 IIS+S D Sbjct: 342 IISASSD 348 Score = 30.0 bits (66), Expect = 3.6 Identities = 18/53 (33%), Positives = 31/53 (58%), Gaps = 3/53 (5%) Frame = +1 Query: 343 PEGA-IVSGGMDTQVLLWNLH--TGEVAGTMKGHTSQVTGLAIDDNGDIISSS 492 P G+ + S G D +LLWN++ G A T+KG++ V L + +G ++ S+ Sbjct: 76 PNGSTLASAGFDRLILLWNVYGDCGNYA-TLKGYSGAVMELHYNTDGSMLFSA 127 Score = 28.9 bits (63), Expect = 8.1 Identities = 13/31 (41%), Positives = 17/31 (54%) Frame = +1 Query: 355 IVSGGMDTQVLLWNLHTGEVAGTMKGHTSQV 447 + S D V +W+ TGE +KGHTS V Sbjct: 124 LFSASTDKTVAVWDSETGERVKRLKGHTSFV 154
>PRP46_CANAL (Q5A7Q3) Pre-mRNA-splicing factor PRP46 (Pre-mRNA-processing| protein 46) Length = 389 Score = 47.8 bits (112), Expect = 2e-05 Identities = 36/124 (29%), Positives = 56/124 (45%), Gaps = 2/124 (1%) Frame = +1 Query: 133 LSAQLHGHEDDVRGICICG-DVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVG 309 L A L GH +R +CI + + DK++R W ++ GH V Sbjct: 120 LKAVLTGHVLGIRSLCISKRHPYLFSGGEDKSLRCWDLERSNSDAGCQIRSYHGHLGGVY 179 Query: 310 PMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNG-DIIS 486 + P D + SGG D V +W++ + A T+ GHT+ +T + D N +I+ Sbjct: 180 SIGLHPELD-----VLFSGGKDCVVRVWDIRSRVEAMTLLGHTNDITSIETDYNDPQVIT 234 Query: 487 SSMD 498 SSMD Sbjct: 235 SSMD 238 Score = 35.8 bits (81), Expect = 0.066 Identities = 30/122 (24%), Positives = 53/122 (43%), Gaps = 11/122 (9%) Frame = +1 Query: 148 HGHEDDVRGICICGDVGVATSS-RDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWA 324 HGH V I + ++ V S +D VR W R V + TL+GH++ + + Sbjct: 172 HGHLGGVYSIGLHPELDVLFSGGKDCVVRVWDI-----RSRVEAMTLLGHTNDITSI--- 223 Query: 325 PPSDRFPEGAIVSGGMDTQVLLWNLHTGEVA----------GTMKGHTSQVTGLAIDDNG 474 + + +++ MD + LW+L + +MK H + T ++ D NG Sbjct: 224 --ETDYNDPQVITSSMDGTIRLWDLRKSKTELLITNHSKSIRSMKSHPKEATFVSGDSNG 281 Query: 475 DI 480 +I Sbjct: 282 EI 283 Score = 32.7 bits (73), Expect = 0.56 Identities = 27/91 (29%), Positives = 36/91 (39%), Gaps = 1/91 (1%) Frame = +1 Query: 145 LHGHEDDVRGI-CICGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVW 321 L GH +D+ I D V TSS D T+R W K + HS + M Sbjct: 213 LLGHTNDITSIETDYNDPQVITSSMDGTIRLWDLRKSK-----TELLITNHSKSIRSMKS 267 Query: 322 APPSDRFPEGAIVSGGMDTQVLLWNLHTGEV 414 P E VSG + ++ W L GE+ Sbjct: 268 HP-----KEATFVSGDSNGEIKQWLLPKGEL 293
>YKY4_CAEEL (Q17963) Hypothetical WD-repeat protein C14B1.4| Length = 376 Score = 47.8 bits (112), Expect = 2e-05 Identities = 33/116 (28%), Positives = 59/116 (50%), Gaps = 1/116 (0%) Frame = +1 Query: 145 LHGHEDDVRGICICGDVG-VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVW 321 L GH+ V I D V ++S DKT++ + + ++KTL GH+++V + Sbjct: 125 LTGHKLGVNDIAWSSDSRCVVSASDDKTLKIFEIVTSR-----MTKTLKGHNNYVFCCNF 179 Query: 322 APPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISS 489 P S +VSG D V +W++ TG T+ H+ V+ ++ + +G +I+S Sbjct: 180 NPQSS-----LVVSGSFDESVRIWDVKTGMCIKTLPAHSDPVSAVSFNRDGSLIAS 230 Score = 46.6 bits (109), Expect = 4e-05 Identities = 32/111 (28%), Positives = 47/111 (42%), Gaps = 2/111 (1%) Frame = +1 Query: 121 AAYHLSAQLHGHEDDVRGICI--CGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGH 294 A Y L L GH + CG + TSS DKTV+ W + +TL GH Sbjct: 75 ANYKLMCTLEGHTKSISSAKFSPCGKY-LGTSSADKTVKIWNMD-----HMICERTLTGH 128 Query: 295 SSFVGPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQV 447 V + W+ S +VS D + ++ + T + T+KGH + V Sbjct: 129 KLGVNDIAWSSDS-----RCVVSASDDKTLKIFEIVTSRMTKTLKGHNNYV 174 Score = 35.4 bits (80), Expect = 0.086 Identities = 16/45 (35%), Positives = 25/45 (55%) Frame = +1 Query: 355 IVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISS 489 I+SG D ++ +WNL T E+ ++GHT V +II+S Sbjct: 316 IISGSEDCKIYIWNLQTREIVQCLEGHTQPVLASDCHPVQNIIAS 360 Score = 30.0 bits (66), Expect = 3.6 Identities = 30/124 (24%), Positives = 48/124 (38%), Gaps = 5/124 (4%) Frame = +1 Query: 145 LHGHEDDVRGICICGDVG-VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVW 321 L H D V + D +A+ S D VR W + KTLV + V Sbjct: 209 LPAHSDPVSAVSFNRDGSLIASGSYDGLVRIWDTANGQ-----CIKTLVDDENPPVAFVK 263 Query: 322 APPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQ----VTGLAIDDNGDIISS 489 P+ ++ I++ +D+ + LW+ G+ GH + ++ IIS Sbjct: 264 FSPNGKY----ILASNLDSTLKLWDFSKGKTLKQYTGHENSKYCIFANFSVTGGKWIISG 319 Query: 490 SMDC 501 S DC Sbjct: 320 SEDC 323
>POP2_SCHPO (O14170) WD-repeat protein pop2 (Proteolysis factor sud1)| Length = 703 Score = 47.4 bits (111), Expect = 2e-05 Identities = 36/118 (30%), Positives = 57/118 (48%) Frame = +1 Query: 145 LHGHEDDVRGICICGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWA 324 L GH D VR I GD+ + + S D ++R W + + L GHS + +++ Sbjct: 503 LIGHTDSVRTISGYGDI-LVSGSYDSSIRIWRVSTGECLYH-----LRGHSLRIYSVLYE 556 Query: 325 PPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSSMD 498 P + +SG MD + +W+L TG ++GH + VT L + N +IS S D Sbjct: 557 PERN-----ICISGSMDKSIRVWDLSTGTCKYVLEGHDAFVTLLNVFQN-RLISGSAD 608 Score = 35.4 bits (80), Expect = 0.086 Identities = 25/101 (24%), Positives = 46/101 (45%) Frame = +1 Query: 169 RGICICGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPE 348 R ICI G S DK++R W + YVL GH +FV + + Sbjct: 559 RNICISG-------SMDKSIRVWDLSTGTCK-YVLE----GHDAFVTLL-------NVFQ 599 Query: 349 GAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDN 471 ++SG D+ + +W+L+TG+ + ++ ++ D++ Sbjct: 600 NRLISGSADSTIRIWDLNTGKPLMVLPSNSGYISSFVSDEH 640 Score = 32.7 bits (73), Expect = 0.56 Identities = 21/65 (32%), Positives = 29/65 (44%) Frame = +1 Query: 268 VLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQV 447 VL L GH V WA + E +VSG +D V +WN+ + +GH S + Sbjct: 382 VLEARLEGHKEGV----WAV---KIHENTLVSGSIDKTVRVWNIEKAKCTHIFRGHISII 434 Query: 448 TGLAI 462 L I Sbjct: 435 RCLEI 439
>PLAP_HUMAN (Q9Y263) Phospholipase A-2-activating protein (PLAP) (PLA2P)| Length = 738 Score = 47.4 bits (111), Expect = 2e-05 Identities = 24/70 (34%), Positives = 38/70 (54%) Frame = +1 Query: 289 GHSSFVGPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDD 468 GHS+FV + P SD +P G I +GG D + +++L + +KGH + V L+ Sbjct: 6 GHSNFVSCVCIIPSSDIYPHGLIATGGNDHNICIFSLDSPMPLYILKGHKNTVCSLSSGK 65 Query: 469 NGDIISSSMD 498 G ++S S D Sbjct: 66 FGTLLSGSWD 75 Score = 40.0 bits (92), Expect = 0.004 Identities = 30/116 (25%), Positives = 50/116 (43%) Frame = +1 Query: 151 GHEDDVRGICICGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPP 330 GHED VRG+ I + + + D ++R W E Y GH++++ + P Sbjct: 132 GHEDCVRGLAILSETEFLSCANDASIRRWQITGECLEVY------YGHTNYIYSISVFPN 185 Query: 331 SDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSSMD 498 F V+ D + +W GE A T++ + + DNGDI+ + D Sbjct: 186 CRDF-----VTTAEDRSLRIWK--HGECAQTIRLPAQSIWCCCVLDNGDIVVGASD 234 Score = 35.4 bits (80), Expect = 0.086 Identities = 34/119 (28%), Positives = 48/119 (40%), Gaps = 1/119 (0%) Frame = +1 Query: 145 LHGHEDDVRGICICGDVGVATS-SRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVW 321 L GH++ V + G G S S D T + W TL GH++ V + Sbjct: 51 LKGHKNTVCSLS-SGKFGTLLSGSWDTTAKVWLNDK-------CMMTLQGHTAAVWAVKI 102 Query: 322 APPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSSMD 498 P +G +++G D V LW G T GH V GLAI + +S + D Sbjct: 103 LPE-----QGLMLTGSADKTVKLWK--AGRCERTFSGHEDCVRGLAILSETEFLSCAND 154
>COR2A_HUMAN (Q92828) Coronin-2A (WD repeat-containing protein 2) (IR10)| Length = 525 Score = 47.4 bits (111), Expect = 2e-05 Identities = 28/108 (25%), Positives = 53/108 (49%), Gaps = 7/108 (6%) Frame = +1 Query: 190 DVGVATSSRDKTVRFWTQHPEKKREYVLS--KTLVGHSSFVGPMVWAPPSDRFPEGAIVS 363 D +A+ S D T++ W+ + + + K LVGH+ VG + W P + + S Sbjct: 95 DFEIASCSEDATIKIWSIPKQLLTRNLTAYRKELVGHARRVGLVEWHPTA----ANILFS 150 Query: 364 GGMDTQVLLWNLHTGEVA-----GTMKGHTSQVTGLAIDDNGDIISSS 492 G D +V++WNL T E T+ H + ++ + NG +++++ Sbjct: 151 AGYDYKVMIWNLDTKESVITSPMSTISCHQDVILSMSFNTNGSLLATT 198
>GBB1_CRIGR (Q6TMK6) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 1 (Transducin beta chain 1) Length = 339 Score = 47.0 bits (110), Expect = 3e-05 Identities = 32/122 (26%), Positives = 49/122 (40%) Frame = +1 Query: 133 LSAQLHGHEDDVRGICICGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGP 312 +S +L GH + D + TSS D T W ++ + T GH+ V Sbjct: 134 VSRELAGHTGYLSCCRFLNDNQIVTSSEDTTCALWDIETGQQ-----TTTFTGHTGDVMS 188 Query: 313 MVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSS 492 + AP + F VSG D LW++ G T GH S + + NG+ ++ Sbjct: 189 LSLAPDTRLF-----VSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATG 243 Query: 493 MD 498 D Sbjct: 244 SD 245 Score = 34.7 bits (78), Expect = 0.15 Identities = 29/115 (25%), Positives = 52/115 (45%), Gaps = 2/115 (1%) Frame = +1 Query: 151 GHEDDVRGICICGDVGV-ATSSRDKTVRFWTQHPEKK-REYVLSKTLVGHSSFVGPMVWA 324 GHE D+ IC + AT S D T R + +++ Y + G +S V Sbjct: 223 GHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITS-----VSF 277 Query: 325 PPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISS 489 S R +++G D +W+ + AG + GH ++V+ L + D+G +++ Sbjct: 278 SKSGRL----LLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVAT 328
>CORO6_RAT (Q920J3) Coronin-6| Length = 472 Score = 47.0 bits (110), Expect = 3e-05 Identities = 35/120 (29%), Positives = 59/120 (49%), Gaps = 6/120 (5%) Frame = +1 Query: 151 GHEDDVRGICIC--GDVGVATSSRDKTVRFWTQHPEKKREYVLSK---TLVGHSSFVGPM 315 GH V I C D +A+ S D TV W Q P+ +++ TL GHS VG + Sbjct: 79 GHTGPVLDIDWCPHNDNVIASPSDDTTVMVW-QIPDYTPVRNITEPVITLEGHSKRVGIL 137 Query: 316 VWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKG-HTSQVTGLAIDDNGDIISSS 492 W P + ++S G D +++WN+ TGEV ++ H + + + NG +++++ Sbjct: 138 SWHPTA----RNVLLSAGGDNVIIIWNVGTGEVLLSLDDIHPDVIHSVCWNSNGSLLATT 193
>TAF5_DROME (P49846) Transcription initiation factor TFIID subunit 5| (Transcription initiation factor TFIID 85 kDa subunit) (p85) (TAFII-80) Length = 704 Score = 47.0 bits (110), Expect = 3e-05 Identities = 26/98 (26%), Positives = 49/98 (50%) Frame = +1 Query: 199 VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDT 378 VAT S D+TVR W + + + GH V + ++ R+ + SG +D Sbjct: 549 VATGSSDRTVRLWDNMTGQS-----VRLMTGHKGSVSSLAFSA-CGRY----LASGSVDH 598 Query: 379 QVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSS 492 +++W+L G + T+ HTS VT + +G +++++ Sbjct: 599 NIIIWDLSNGSLVTTLLRHTSTVTTITFSRDGTVLAAA 636
>PLAP_RAT (P54319) Phospholipase A-2-activating protein (PLAP)| Length = 647 Score = 47.0 bits (110), Expect = 3e-05 Identities = 24/70 (34%), Positives = 37/70 (52%) Frame = +1 Query: 289 GHSSFVGPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDD 468 GHS+FV + P SD +P G I +GG D + +++L + +KGH V L+ Sbjct: 6 GHSNFVSCVCIIPSSDIYPHGLIATGGNDHNICIFSLDSPMPLYILKGHKDTVCSLSSGK 65 Query: 469 NGDIISSSMD 498 G ++S S D Sbjct: 66 FGTLLSGSWD 75 Score = 39.3 bits (90), Expect = 0.006 Identities = 30/116 (25%), Positives = 50/116 (43%) Frame = +1 Query: 151 GHEDDVRGICICGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPP 330 GHED VRG+ I + + + D ++R W E Y GH++++ + P Sbjct: 132 GHEDCVRGLAILSETEFLSCANDASIRRWQITGECLGVY------YGHTNYIYSISVFPN 185 Query: 331 SDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSSMD 498 F V+ D + +W GE A T++ + + DNGDI+ + D Sbjct: 186 CRDF-----VTTAEDRSLRIWK--HGECAQTIRLPAQSIWCCCVLDNGDIVVGASD 234 Score = 37.0 bits (84), Expect = 0.030 Identities = 34/119 (28%), Positives = 48/119 (40%), Gaps = 1/119 (0%) Frame = +1 Query: 145 LHGHEDDVRGICICGDVGVATS-SRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVW 321 L GH+D V + G G S S D T + W TL GH++ V + Sbjct: 51 LKGHKDTVCSLS-SGKFGTLLSGSWDTTAKVWLNDK-------CMMTLQGHTAAVWAVKI 102 Query: 322 APPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSSMD 498 P +G +++G D + LW G T GH V GLAI + +S + D Sbjct: 103 LPE-----QGLMLTGSADKTIKLWK--AGRCERTFSGHEDCVRGLAILSETEFLSCAND 154
>KMHB_DICDI (P90648) Myosin heavy chain kinase B (EC 2.7.11.7) (MHCK B)| Length = 732 Score = 47.0 bits (110), Expect = 3e-05 Identities = 37/128 (28%), Positives = 57/128 (44%), Gaps = 1/128 (0%) Frame = +1 Query: 118 MAAYHLSAQLHGHEDDVRGICICGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHS 297 + + + L GH V ICI G + + S DKT+R W + S TL GH Sbjct: 609 LKTFRCNYTLKGHTKWVTTICILG-TNLYSGSYDKTIRVWNL-----KSLECSATLRGHD 662 Query: 298 SFVGPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAI-DDNG 474 +V MV + + + D + +W+L T T++GH + V LA+ +D Sbjct: 663 RWVEHMVIC-------DKLLFTASDDNTIKIWDLETLRCNTTLEGHNATVQCLAVWEDKK 715 Query: 475 DIISSSMD 498 +IS S D Sbjct: 716 CVISCSHD 723 Score = 43.1 bits (100), Expect = 4e-04 Identities = 29/108 (26%), Positives = 50/108 (46%) Frame = +1 Query: 145 LHGHEDDVRGICICGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWA 324 L H V+ +CI G + + S DKT++ W + + + TL GH+ +V + Sbjct: 578 LESHARAVKTLCISGQY-LFSGSNDKTIKVWDL-----KTFRCNYTLKGHTKWVTTICIL 631 Query: 325 PPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDD 468 + + SG D + +WNL + E + T++GH V + I D Sbjct: 632 GTN-------LYSGSYDKTIRVWNLKSLECSATLRGHDRWVEHMVICD 672 Score = 35.8 bits (81), Expect = 0.066 Identities = 28/106 (26%), Positives = 45/106 (42%) Frame = +1 Query: 145 LHGHEDDVRGICICGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWA 324 L GH+ V + + D + + S DKT++ W + TL H+ V + + Sbjct: 538 LEGHDKPVHTVLL-NDKYLFSGSSDKTIKVWDL-----KTLECKYTLESHARAVKTLCIS 591 Query: 325 PPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAI 462 + SG D + +W+L T T+KGHT VT + I Sbjct: 592 GQY-------LFSGSNDKTIKVWDLKTFRCNYTLKGHTKWVTTICI 630 Score = 32.0 bits (71), Expect = 0.95 Identities = 24/98 (24%), Positives = 46/98 (46%) Frame = +1 Query: 175 ICICGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGA 354 +CIC ++ + T D ++R + K + +TL GH GP+ +D++ Sbjct: 466 LCICDNL-LFTGCSDNSIRVYDY---KSQNMECVQTLKGHE---GPVESICYNDQY---- 514 Query: 355 IVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDD 468 + SG D + +W+L T++GH V + ++D Sbjct: 515 LFSGSSDHSIKVWDLKKLRCIFTLEGHDKPVHTVLLND 552
>PLAP_MOUSE (P27612) Phospholipase A-2-activating protein (PLAP)| Length = 646 Score = 47.0 bits (110), Expect = 3e-05 Identities = 24/70 (34%), Positives = 37/70 (52%) Frame = +1 Query: 289 GHSSFVGPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDD 468 GHS+FV + P SD +P G I +GG D + +++L + +KGH V L+ Sbjct: 6 GHSNFVSYVCIIPSSDIYPHGLIATGGNDHNICIFSLDSPMPLYILKGHKDTVCSLSSGK 65 Query: 469 NGDIISSSMD 498 G ++S S D Sbjct: 66 FGTLLSGSWD 75 Score = 40.8 bits (94), Expect = 0.002 Identities = 30/116 (25%), Positives = 51/116 (43%) Frame = +1 Query: 151 GHEDDVRGICICGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPP 330 GHED VRG+ I + + + D ++R W E Y GH++++ + P Sbjct: 132 GHEDCVRGLAILSETEFLSCANDASIRRWQITGECLEVY------FGHTNYIYSISVFPN 185 Query: 331 SDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSSMD 498 S F V+ D + +W GE A T++ + + +NGDI+ + D Sbjct: 186 SKDF-----VTTAEDRSLRIWK--HGECAQTIRLPAQSIWCCCVLENGDIVVGASD 234 Score = 36.2 bits (82), Expect = 0.051 Identities = 34/119 (28%), Positives = 48/119 (40%), Gaps = 1/119 (0%) Frame = +1 Query: 145 LHGHEDDVRGICICGDVGVATS-SRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVW 321 L GH+D V + G G S S D T + W TL GH++ V + Sbjct: 51 LKGHKDTVCSLS-SGKFGTLLSGSWDTTAKVWLNDK-------CMMTLQGHTAAVWAVKI 102 Query: 322 APPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSSMD 498 P +G +++G D + LW G T GH V GLAI + +S + D Sbjct: 103 LPE-----QGLMLTGSADKTIKLWK--AGRCERTFLGHEDCVRGLAILSETEFLSCAND 154
>WDR71_CHICK (Q5ZK69) WD-repeat protein 71| Length = 392 Score = 47.0 bits (110), Expect = 3e-05 Identities = 39/129 (30%), Positives = 59/129 (45%), Gaps = 2/129 (1%) Frame = +1 Query: 118 MAAYHLSAQLHGHEDDVRGICICGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHS 297 +A Y +++H I G +GV+TS+ D T++ W + R + L GH Sbjct: 81 LAPYTTFSRIHQKSITCLDISSGGGLGVSTST-DGTMKIWQAANGEIR-----RLLEGHV 134 Query: 298 SFVGPMVWAPPSDRFPEGAIV-SGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNG 474 V + FP G +V SGGMD Q+ +W+ T KGH + AI D G Sbjct: 135 YDVNCCRF------FPSGLVVLSGGMDAQLKIWSAEDASCVVTFKGHKGGILDTAIVDRG 188 Query: 475 -DIISSSMD 498 +++S S D Sbjct: 189 RNVLSCSRD 197
>COR2A_MOUSE (Q8C0P5) Coronin-2A| Length = 524 Score = 46.6 bits (109), Expect = 4e-05 Identities = 28/108 (25%), Positives = 55/108 (50%), Gaps = 7/108 (6%) Frame = +1 Query: 190 DVGVATSSRDKTVRFWTQHPEKKREYVLS--KTLVGHSSFVGPMVWAPPSDRFPEGAIVS 363 D +A+ S D T++ W + + + K L+GH+ VG + W P + + S Sbjct: 95 DFEIASCSEDATIKIWNIPKQLLTRNLTTYRKELIGHARRVGLVEWHPTT----ANILFS 150 Query: 364 GGMDTQVLLWNLHTGE--VAG---TMKGHTSQVTGLAIDDNGDIISSS 492 G D +V++WNL T + +AG T+ H + ++ + NG +++++ Sbjct: 151 AGYDYKVMVWNLDTKDSVIAGPVKTINCHQDVILSMSFNTNGSLLATT 198
>FBXW7_DROME (Q9VZF4) F-box/WD-repeat protein 7 (F-box and WD-40 domain protein 7)| (Protein archipelago) Length = 1326 Score = 46.2 bits (108), Expect = 5e-05 Identities = 32/109 (29%), Positives = 54/109 (49%) Frame = +1 Query: 145 LHGHEDDVRGICICGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWA 324 L GH VR + G + + + + D V+ W HPE++ TL GH++ V + Sbjct: 1111 LVGHLAAVRCVQYDGKL-IVSGAYDYMVKIW--HPERQE---CLHTLQGHTNRVYSL--- 1161 Query: 325 PPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDN 471 +F +VSG +DT + +W++ TG T+ GH S +G+ + N Sbjct: 1162 ----QFDGLHVVSGSLDTSIRVWDVETGNCKHTLMGHQSLTSGMELRQN 1206 Score = 45.4 bits (106), Expect = 8e-05 Identities = 33/118 (27%), Positives = 54/118 (45%) Frame = +1 Query: 145 LHGHEDDVRGICICGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWA 324 L GH+D V + + S D T++ W+ K +TLVGH+ V W Sbjct: 990 LKGHDDHVITCLQFSGNRIVSGSDDNTLKVWSAVNGK-----CLRTLVGHTGGV----W- 1039 Query: 325 PPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSSMD 498 S + I+SG D + +W++ +G T++GHTS V + + ++S S D Sbjct: 1040 --SSQMSGNIIISGSTDRTLKVWDMDSGACVHTLQGHTSTVRCMHL-HGSKVVSGSRD 1094 Score = 40.8 bits (94), Expect = 0.002 Identities = 33/118 (27%), Positives = 51/118 (43%), Gaps = 3/118 (2%) Frame = +1 Query: 145 LHGHEDDVRGICICGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWA 324 L GH + V + G + V + S D ++R W + TL+GH S M Sbjct: 1151 LQGHTNRVYSLQFDG-LHVVSGSLDTSIRVWDVETGNCKH-----TLMGHQSLTSGM--- 1201 Query: 325 PPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKG---HTSQVTGLAIDDNGDIISS 489 + +VSG D+ V +W++ TG+ T+ G H S VT L + + SS Sbjct: 1202 ----ELRQNILVSGNADSTVKVWDITTGQCLQTLSGPNKHHSAVTCLQFNSRFVVTSS 1255 Score = 32.3 bits (72), Expect = 0.73 Identities = 26/107 (24%), Positives = 43/107 (40%) Frame = +1 Query: 145 LHGHEDDVRGICICGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWA 324 L GH V + G++ + + S D+T++ W TL GH+S V M Sbjct: 1031 LVGHTGGVWSSQMSGNI-IISGSTDRTLKVWDMDSG-----ACVHTLQGHTSTVRCM--- 1081 Query: 325 PPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAID 465 +VSG D + +W++ G + GH + V + D Sbjct: 1082 ----HLHGSKVVSGSRDATLRVWDIEQGSCLHVLVGHLAAVRCVQYD 1124
>GBB1_XENLA (P79959) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 1 (Transducin beta chain 1) (XGbeta1) Length = 340 Score = 46.2 bits (108), Expect = 5e-05 Identities = 33/122 (27%), Positives = 49/122 (40%) Frame = +1 Query: 133 LSAQLHGHEDDVRGICICGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGP 312 +S +L GH + D + TSS D T W ++ + T GH+ V Sbjct: 135 VSRELAGHTGYLSCCRFLDDNQIITSSGDTTCALWDIETGQQ-----TTTFTGHTGDVMS 189 Query: 313 MVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSS 492 + AP S F VSG D LW++ G T GH S + + NG+ ++ Sbjct: 190 LSLAPDSRCF-----VSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATG 244 Query: 493 MD 498 D Sbjct: 245 SD 246 Score = 34.3 bits (77), Expect = 0.19 Identities = 29/115 (25%), Positives = 52/115 (45%), Gaps = 2/115 (1%) Frame = +1 Query: 151 GHEDDVRGICICGDVGV-ATSSRDKTVRFWTQHPEKK-REYVLSKTLVGHSSFVGPMVWA 324 GHE D+ IC + AT S D T R + +++ Y + G +S V Sbjct: 224 GHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMVYSHDNIICGITS-----VAF 278 Query: 325 PPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISS 489 S R +++G D +W+ + AG + GH ++V+ L + D+G +++ Sbjct: 279 SKSGRL----LLAGYDDFNCNVWDTLKADRAGVLAGHDNRVSCLGVTDDGMAVAT 329
>WDR26_MOUSE (Q8C6G8) WD-repeat protein 26| Length = 514 Score = 45.8 bits (107), Expect = 6e-05 Identities = 31/95 (32%), Positives = 51/95 (53%), Gaps = 3/95 (3%) Frame = +1 Query: 199 VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMD- 375 +AT S+D TV W P+ +L KTL GH+ V + W+P + +V+ G D Sbjct: 223 LATGSKDTTVIIWQVDPDTHLLKLL-KTLEGHAYGVSYIAWSP-----DDSYLVACGPDD 276 Query: 376 -TQVLLWNLHTGEVAGTM-KGHTSQVTGLAIDDNG 474 +++ LWN+ TGE+ M + H +T +A + +G Sbjct: 277 CSELWLWNVQTGELRTKMSQSHEDSLTSVAWNPDG 311
>WDR26_HUMAN (Q9H7D7) WD-repeat protein 26| Length = 514 Score = 45.8 bits (107), Expect = 6e-05 Identities = 31/95 (32%), Positives = 51/95 (53%), Gaps = 3/95 (3%) Frame = +1 Query: 199 VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMD- 375 +AT S+D TV W P+ +L KTL GH+ V + W+P + +V+ G D Sbjct: 223 LATGSKDTTVIIWQVDPDTHLLKLL-KTLEGHAYGVSYIAWSP-----DDNYLVACGPDD 276 Query: 376 -TQVLLWNLHTGEVAGTM-KGHTSQVTGLAIDDNG 474 +++ LWN+ TGE+ M + H +T +A + +G Sbjct: 277 CSELWLWNVQTGELRTKMSQSHEDSLTSVAWNPDG 311
>GBB1_RAT (P54311) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 1 (Transducin beta chain 1) Length = 339 Score = 45.8 bits (107), Expect = 6e-05 Identities = 32/122 (26%), Positives = 49/122 (40%) Frame = +1 Query: 133 LSAQLHGHEDDVRGICICGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGP 312 +S +L GH + D + TSS D T W ++ + T GH+ V Sbjct: 134 VSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCALWDIETGQQ-----TTTFTGHTGDVMS 188 Query: 313 MVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSS 492 + AP + F VSG D LW++ G T GH S + + NG+ ++ Sbjct: 189 LSLAPDTRLF-----VSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATG 243 Query: 493 MD 498 D Sbjct: 244 SD 245 Score = 34.7 bits (78), Expect = 0.15 Identities = 29/115 (25%), Positives = 52/115 (45%), Gaps = 2/115 (1%) Frame = +1 Query: 151 GHEDDVRGICICGDVGV-ATSSRDKTVRFWTQHPEKK-REYVLSKTLVGHSSFVGPMVWA 324 GHE D+ IC + AT S D T R + +++ Y + G +S V Sbjct: 223 GHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITS-----VSF 277 Query: 325 PPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISS 489 S R +++G D +W+ + AG + GH ++V+ L + D+G +++ Sbjct: 278 SKSGRL----LLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVAT 328
>GBB1_PONPY (Q5R5W8) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 1 (Transducin beta chain 1) Length = 339 Score = 45.8 bits (107), Expect = 6e-05 Identities = 32/122 (26%), Positives = 49/122 (40%) Frame = +1 Query: 133 LSAQLHGHEDDVRGICICGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGP 312 +S +L GH + D + TSS D T W ++ + T GH+ V Sbjct: 134 VSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCALWDIETGQQ-----TTTFTGHTGDVMS 188 Query: 313 MVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSS 492 + AP + F VSG D LW++ G T GH S + + NG+ ++ Sbjct: 189 LSLAPDTRLF-----VSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATG 243 Query: 493 MD 498 D Sbjct: 244 SD 245 Score = 34.3 bits (77), Expect = 0.19 Identities = 29/115 (25%), Positives = 51/115 (44%), Gaps = 2/115 (1%) Frame = +1 Query: 151 GHEDDVRGICICGDVGV-ATSSRDKTVRFWTQHPEKK-REYVLSKTLVGHSSFVGPMVWA 324 GHE D+ IC + AT S D T R + +++ Y + G +S V Sbjct: 223 GHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITS-----VSF 277 Query: 325 PPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISS 489 S R +++G D +W+ + AG + GH +V+ L + D+G +++ Sbjct: 278 SKSGRL----LLAGYDDFNCNVWDALKADRAGVLAGHDDRVSCLGVTDDGMAVAT 328
>GBB1_MOUSE (P62874) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 1 (Transducin beta chain 1) Length = 339 Score = 45.8 bits (107), Expect = 6e-05 Identities = 32/122 (26%), Positives = 49/122 (40%) Frame = +1 Query: 133 LSAQLHGHEDDVRGICICGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGP 312 +S +L GH + D + TSS D T W ++ + T GH+ V Sbjct: 134 VSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCALWDIETGQQ-----TTTFTGHTGDVMS 188 Query: 313 MVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSS 492 + AP + F VSG D LW++ G T GH S + + NG+ ++ Sbjct: 189 LSLAPDTRLF-----VSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATG 243 Query: 493 MD 498 D Sbjct: 244 SD 245 Score = 34.7 bits (78), Expect = 0.15 Identities = 29/115 (25%), Positives = 52/115 (45%), Gaps = 2/115 (1%) Frame = +1 Query: 151 GHEDDVRGICICGDVGV-ATSSRDKTVRFWTQHPEKK-REYVLSKTLVGHSSFVGPMVWA 324 GHE D+ IC + AT S D T R + +++ Y + G +S V Sbjct: 223 GHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITS-----VSF 277 Query: 325 PPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISS 489 S R +++G D +W+ + AG + GH ++V+ L + D+G +++ Sbjct: 278 SKSGRL----LLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVAT 328
>GBB1_HUMAN (P62873) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 1 (Transducin beta chain 1) Length = 339 Score = 45.8 bits (107), Expect = 6e-05 Identities = 32/122 (26%), Positives = 49/122 (40%) Frame = +1 Query: 133 LSAQLHGHEDDVRGICICGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGP 312 +S +L GH + D + TSS D T W ++ + T GH+ V Sbjct: 134 VSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCALWDIETGQQ-----TTTFTGHTGDVMS 188 Query: 313 MVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSS 492 + AP + F VSG D LW++ G T GH S + + NG+ ++ Sbjct: 189 LSLAPDTRLF-----VSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATG 243 Query: 493 MD 498 D Sbjct: 244 SD 245 Score = 34.7 bits (78), Expect = 0.15 Identities = 29/115 (25%), Positives = 52/115 (45%), Gaps = 2/115 (1%) Frame = +1 Query: 151 GHEDDVRGICICGDVGV-ATSSRDKTVRFWTQHPEKK-REYVLSKTLVGHSSFVGPMVWA 324 GHE D+ IC + AT S D T R + +++ Y + G +S V Sbjct: 223 GHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITS-----VSF 277 Query: 325 PPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISS 489 S R +++G D +W+ + AG + GH ++V+ L + D+G +++ Sbjct: 278 SKSGRL----LLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVAT 328
>GBB1_CANFA (P62872) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 1 (Transducin beta chain 1) Length = 339 Score = 45.8 bits (107), Expect = 6e-05 Identities = 32/122 (26%), Positives = 49/122 (40%) Frame = +1 Query: 133 LSAQLHGHEDDVRGICICGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGP 312 +S +L GH + D + TSS D T W ++ + T GH+ V Sbjct: 134 VSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCALWDIETGQQ-----TTTFTGHTGDVMS 188 Query: 313 MVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSS 492 + AP + F VSG D LW++ G T GH S + + NG+ ++ Sbjct: 189 LSLAPDTRLF-----VSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATG 243 Query: 493 MD 498 D Sbjct: 244 SD 245 Score = 34.7 bits (78), Expect = 0.15 Identities = 29/115 (25%), Positives = 52/115 (45%), Gaps = 2/115 (1%) Frame = +1 Query: 151 GHEDDVRGICICGDVGV-ATSSRDKTVRFWTQHPEKK-REYVLSKTLVGHSSFVGPMVWA 324 GHE D+ IC + AT S D T R + +++ Y + G +S V Sbjct: 223 GHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITS-----VSF 277 Query: 325 PPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISS 489 S R +++G D +W+ + AG + GH ++V+ L + D+G +++ Sbjct: 278 SKSGRL----LLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVAT 328
>GBB1_BRARE (Q6PH57) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 1 (Transducin beta chain 1) Length = 340 Score = 45.8 bits (107), Expect = 6e-05 Identities = 32/122 (26%), Positives = 49/122 (40%) Frame = +1 Query: 133 LSAQLHGHEDDVRGICICGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGP 312 +S +L GH + D + TSS D T W ++ + T GH+ V Sbjct: 135 VSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCALWDIETGQQ-----TTTFAGHTGDVMS 189 Query: 313 MVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSS 492 + AP + F VSG D LW++ G T GH S + + NG+ ++ Sbjct: 190 LSLAPDTRLF-----VSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATG 244 Query: 493 MD 498 D Sbjct: 245 SD 246 Score = 34.3 bits (77), Expect = 0.19 Identities = 29/115 (25%), Positives = 52/115 (45%), Gaps = 2/115 (1%) Frame = +1 Query: 151 GHEDDVRGICICGDVGV-ATSSRDKTVRFWTQHPEKK-REYVLSKTLVGHSSFVGPMVWA 324 GHE D+ IC + AT S D T R + +++ Y + G +S V Sbjct: 224 GHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMVYSHDNIICGITS-----VAF 278 Query: 325 PPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISS 489 S R +++G D +W+ + AG + GH ++V+ L + D+G +++ Sbjct: 279 SKSGRL----LLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVAT 329
>GBB1_BOVIN (P62871) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 1 (Transducin beta chain 1) Length = 339 Score = 45.8 bits (107), Expect = 6e-05 Identities = 32/122 (26%), Positives = 49/122 (40%) Frame = +1 Query: 133 LSAQLHGHEDDVRGICICGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGP 312 +S +L GH + D + TSS D T W ++ + T GH+ V Sbjct: 134 VSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCALWDIETGQQ-----TTTFTGHTGDVMS 188 Query: 313 MVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSS 492 + AP + F VSG D LW++ G T GH S + + NG+ ++ Sbjct: 189 LSLAPDTRLF-----VSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATG 243 Query: 493 MD 498 D Sbjct: 244 SD 245 Score = 34.7 bits (78), Expect = 0.15 Identities = 29/115 (25%), Positives = 52/115 (45%), Gaps = 2/115 (1%) Frame = +1 Query: 151 GHEDDVRGICICGDVGV-ATSSRDKTVRFWTQHPEKK-REYVLSKTLVGHSSFVGPMVWA 324 GHE D+ IC + AT S D T R + +++ Y + G +S V Sbjct: 223 GHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITS-----VSF 277 Query: 325 PPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISS 489 S R +++G D +W+ + AG + GH ++V+ L + D+G +++ Sbjct: 278 SKSGRL----LLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVAT 328
>GBLP_NEUCR (Q01369) Guanine nucleotide-binding protein beta subunit-like| protein (Cross-pathway control WD-repeat protein cpc-2) Length = 316 Score = 45.4 bits (106), Expect = 8e-05 Identities = 30/114 (26%), Positives = 53/114 (46%), Gaps = 1/114 (0%) Frame = +1 Query: 151 GHEDDVRGICICGDVG-VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAP 327 GH +DV + D + + SRD+T++ W + K + T GH+ +V + ++P Sbjct: 103 GHTNDVLSVSFSADNRQIVSGSRDRTIKLWNTLGDCK----FTITEKGHTEWVSCVRFSP 158 Query: 328 PSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISS 489 IVS G D V +W L + ++ GHT + + I +G + +S Sbjct: 159 NPQN---PVIVSSGWDKLVKVWELSSCKLQTDHIGHTGYINAVTISPDGSLCAS 209 Score = 40.8 bits (94), Expect = 0.002 Identities = 30/100 (30%), Positives = 44/100 (44%), Gaps = 2/100 (2%) Frame = +1 Query: 205 TSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAI-VSGGMDTQ 381 + SRDK++ W ++ + L GHS V V + +GA +S D Sbjct: 33 SGSRDKSLIIWNLTRDETSYGYPKRRLHGHSHIVSDCVISS------DGAYALSASWDKT 86 Query: 382 VLLWNLHTGEVAGTMKGHTSQVTGLAID-DNGDIISSSMD 498 + LW L TG GHT+ V ++ DN I+S S D Sbjct: 87 LRLWELSTGTTTRRFVGHTNDVLSVSFSADNRQIVSGSRD 126
>PRP19_HUMAN (Q9UMS4) Pre-mRNA-splicing factor 19 (PRP19/PSO4 homolog) (Nuclear| matrix protein 200) (hPso4) Length = 504 Score = 45.4 bits (106), Expect = 8e-05 Identities = 35/137 (25%), Positives = 59/137 (43%), Gaps = 5/137 (3%) Frame = +1 Query: 103 RPAPLMAAYHLSAQLHGHEDDVRGI-----CICGDVGVATSSRDKTVRFWTQHPEKKREY 267 +P L +++ + H + GI C + T DK V + +K E Sbjct: 200 KPEELSKYRQVASHVGLHSASIPGILALDLCPSDTNKILTGGADKNVVVF----DKSSEQ 255 Query: 268 VLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQV 447 +L+ TL GH+ V +V+ P D + S D + +W++ ++ H S V Sbjct: 256 ILA-TLKGHTKKVTSVVFHPSQD-----LVFSASPDATIRIWSVPNASCVQVVRAHESAV 309 Query: 448 TGLAIDDNGDIISSSMD 498 TGL++ GD + SS D Sbjct: 310 TGLSLHATGDYLLSSSD 326 Score = 40.0 bits (92), Expect = 0.004 Identities = 26/93 (27%), Positives = 46/93 (49%) Frame = +1 Query: 214 RDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDTQVLLW 393 R KTV PE+ +Y + VG S P + A I++GG D V+++ Sbjct: 190 RGKTVPEELVKPEELSKYRQVASHVGLHSASIPGILALDLCPSDTNKILTGGADKNVVVF 249 Query: 394 NLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSS 492 + + ++ T+KGHT +VT + + D++ S+ Sbjct: 250 DKSSEQILATLKGHTKKVTSVVFHPSQDLVFSA 282 Score = 37.4 bits (85), Expect = 0.023 Identities = 16/53 (30%), Positives = 30/53 (56%), Gaps = 1/53 (1%) Frame = +1 Query: 343 PEGAIV-SGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSSMD 498 P+G I +G MD+Q+ +W+L GH+ +T +A +NG ++++ D Sbjct: 360 PDGLIFGTGTMDSQIKIWDLKERTNVANFPGHSGPITSIAFSENGYYLATAAD 412
>NLE1_BOVIN (Q58D20) Notchless homolog 1| Length = 485 Score = 45.4 bits (106), Expect = 8e-05 Identities = 34/116 (29%), Positives = 53/116 (45%), Gaps = 3/116 (2%) Frame = +1 Query: 121 AAYHLSAQLHGHEDDVRGICICGDVG--VATSSRDKTVRFWTQHPEKKREYVLSKTLVGH 294 A ++ L GH + V + G +A+ S D TVRFW E T GH Sbjct: 102 AVTRCTSSLEGHSEAVISVAF-SPTGKYLASGSGDTTVRFWDLSTETPH-----FTCQGH 155 Query: 295 SSFVGPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAG-TMKGHTSQVTGLA 459 +V + W+P + + SG + Q+LLW+ TG+ G + GH+ +T L+ Sbjct: 156 RHWVLSISWSPDGKK-----LASGCKNGQILLWDPSTGKQVGRALTGHSKWITALS 206 Score = 43.1 bits (100), Expect = 4e-04 Identities = 25/88 (28%), Positives = 41/88 (46%) Frame = +1 Query: 199 VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDT 378 VA+SS+D +VR W + +TL GH+ V + W +G + S D Sbjct: 219 VASSSKDGSVRVWDTTAGR-----CERTLTGHAQSVTCLRWGG------DGLLYSASQDR 267 Query: 379 QVLLWNLHTGEVAGTMKGHTSQVTGLAI 462 + +W H G + T++GH V +A+ Sbjct: 268 TIKVWRAHDGVLCRTLQGHGHWVNTMAL 295 Score = 40.4 bits (93), Expect = 0.003 Identities = 27/105 (25%), Positives = 49/105 (46%), Gaps = 1/105 (0%) Frame = +1 Query: 187 GDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSG 366 G + + S D T+ W+ +KK + GH + + +V++P S I S Sbjct: 340 GPERLVSGSDDFTLFLWSPAEDKKP----LARMTGHQALINQVVFSPDSR-----VIASA 390 Query: 367 GMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAID-DNGDIISSSMD 498 D + LW+ TG+ +++GH + V +A D+ ++S S D Sbjct: 391 SFDKSIKLWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSD 435 Score = 40.0 bits (92), Expect = 0.004 Identities = 29/118 (24%), Positives = 58/118 (49%), Gaps = 1/118 (0%) Frame = +1 Query: 139 AQLHGHEDDVRGICICGDVGV-ATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPM 315 A++ GH+ + + D V A++S DK+++ W K Y+ S L GH + V + Sbjct: 366 ARMTGHQALINQVVFSPDSRVIASASFDKSIKLWDGRTGK---YLAS--LRGHVAAVYQI 420 Query: 316 VWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISS 489 W+ S +VSG D+ + +W++ +++ + GH +V + +G ++S Sbjct: 421 AWSADSR-----LLVSGSSDSTLKVWDVKAQKLSTDLPGHADEVYAVDWSPDGQRVAS 473 Score = 35.4 bits (80), Expect = 0.086 Identities = 27/86 (31%), Positives = 37/86 (43%), Gaps = 1/86 (1%) Frame = +1 Query: 139 AQLHGHEDDVRGICICGDVGVATS-SRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPM 315 A L GH V I D + S S D T++ W +K LS L GH+ V + Sbjct: 408 ASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQK-----LSTDLPGHADEVYAV 462 Query: 316 VWAPPSDRFPEGAIVSGGMDTQVLLW 393 W+P R + SGG D + +W Sbjct: 463 DWSPDGQR-----VASGGKDKCLRIW 483 Score = 33.1 bits (74), Expect = 0.43 Identities = 19/57 (33%), Positives = 30/57 (52%) Frame = +1 Query: 145 LHGHEDDVRGICICGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPM 315 L GH V + GD + ++S+D+T++ W H + VL +TL GH +V M Sbjct: 242 LTGHAQSVTCLRWGGDGLLYSASQDRTIKVWRAH-----DGVLCRTLQGHGHWVNTM 293 Score = 30.4 bits (67), Expect = 2.8 Identities = 20/72 (27%), Positives = 33/72 (45%) Frame = +1 Query: 274 SKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTG 453 + +L GHS V + ++P + SG DT V W+L T T +GH V Sbjct: 107 TSSLEGHSEAVISVAFSPTGKY-----LASGSGDTTVRFWDLSTETPHFTCQGHRHWVLS 161 Query: 454 LAIDDNGDIISS 489 ++ +G ++S Sbjct: 162 ISWSPDGKKLAS 173
>WDR48_PONPY (Q5RAW8) WD-repeat protein 48| Length = 677 Score = 45.4 bits (106), Expect = 8e-05 Identities = 25/96 (26%), Positives = 46/96 (47%) Frame = +1 Query: 205 TSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDTQV 384 T+ RD +R W+ + K+ Y+ S + H+ +V +V ++S DT V Sbjct: 47 TAGRDSIIRIWSVNQHKQDPYIAS--MEHHTDWVNDIVLCCNGK-----TLISASSDTTV 99 Query: 385 LLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSS 492 +WN H G T++ H V LA + ++++S+ Sbjct: 100 KVWNAHKGFCMSTLRTHKDYVKALAYAKDKELVASA 135
>WDR48_HUMAN (Q8TAF3) WD-repeat protein 48 (WD repeat endosomal protein) (p80)| Length = 677 Score = 45.4 bits (106), Expect = 8e-05 Identities = 25/96 (26%), Positives = 46/96 (47%) Frame = +1 Query: 205 TSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDTQV 384 T+ RD +R W+ + K+ Y+ S + H+ +V +V ++S DT V Sbjct: 47 TAGRDSIIRIWSVNQHKQDPYIAS--MEHHTDWVNDIVLCCNGK-----TLISASSDTTV 99 Query: 385 LLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSS 492 +WN H G T++ H V LA + ++++S+ Sbjct: 100 KVWNAHKGFCMSTLRTHKDYVKALAYAKDKELVASA 135
>PRP46_DEBHA (Q6BU94) Pre-mRNA-splicing factor PRP46 (Pre-mRNA-processing| protein 46) Length = 417 Score = 45.4 bits (106), Expect = 8e-05 Identities = 35/129 (27%), Positives = 56/129 (43%), Gaps = 2/129 (1%) Frame = +1 Query: 118 MAAYHLSAQLHGHEDDVRGICICGDVGVATS-SRDKTVRFWTQHPEKKREYVLSKTLVGH 294 +A+ +L A + GH VR + + S S DKTV+ W + GH Sbjct: 151 LASLNLKATITGHIMGVRSLAVSSRYPYLFSGSEDKTVKCWDLERTNSLLGCQIRNYHGH 210 Query: 295 SSFVGPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAID-DN 471 + M P D + +GG D+ + +W+L + + GH S +T +A + Sbjct: 211 VGGIYAMALHPELD-----LLFTGGRDSVIRVWDLRSRTEIMVLSGHRSDITSIASQIGD 265 Query: 472 GDIISSSMD 498 II+SSMD Sbjct: 266 PQIITSSMD 274 Score = 35.8 bits (81), Expect = 0.066 Identities = 33/122 (27%), Positives = 49/122 (40%), Gaps = 4/122 (3%) Frame = +1 Query: 145 LHGHEDDVRGICI-CGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVW 321 L GH D+ I GD + TSS D T+R W R+ L HS + M Sbjct: 249 LSGHRSDITSIASQIGDPQIITSSMDATIRLW-----DIRKATTQLALTHHSKSIRLMAM 303 Query: 322 APPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQ---VTGLAIDDNGDIISSS 492 P E + SG + W L GE+ GH+ + + L+I+ + + + S Sbjct: 304 HP-----QEMTMCSGDTSGNLKEWLLPGGELLNEF-GHSGENKIINTLSINPSNNTLFSG 357 Query: 493 MD 498 D Sbjct: 358 YD 359 Score = 29.6 bits (65), Expect = 4.7 Identities = 17/73 (23%), Positives = 35/73 (47%), Gaps = 1/73 (1%) Frame = +1 Query: 247 PEKKREYVLSKTLVG-HSSFVGPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGT 423 P+ + L + + G H +V P ++++ V+G D+ + +W+L + + T Sbjct: 104 PDSDSRWKLLRVMAGAHQGWVRSCTVDPVTNKW----FVTGSSDSTIKIWDLASLNLKAT 159 Query: 424 MKGHTSQVTGLAI 462 + GH V LA+ Sbjct: 160 ITGHIMGVRSLAV 172
>TRCB_XENLA (Q91854) Beta-TrCP (Beta-transducin repeat-containing protein)| Length = 518 Score = 45.4 bits (106), Expect = 8e-05 Identities = 31/125 (24%), Positives = 60/125 (48%), Gaps = 2/125 (1%) Frame = +1 Query: 130 HLSAQLHGHEDDVRGI-CI-CGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSF 303 H ++H + +G+ C+ D + + RD T++ W K + L+GH+ Sbjct: 220 HSLQRIHCRSETSKGVYCLQYDDQKIVSGLRDNTIKIWD-----KNTLECKRVLMGHTGS 274 Query: 304 VGPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDII 483 V + ++ E I++G D+ V +W+++TGE+ T+ H V L +NG ++ Sbjct: 275 VLCL-------QYDERVIITGSSDSTVRVWDVNTGEMLNTLIHHCEAVLHLRF-NNGMMV 326 Query: 484 SSSMD 498 + S D Sbjct: 327 TCSKD 331 Score = 38.1 bits (87), Expect = 0.013 Identities = 26/103 (25%), Positives = 48/103 (46%) Frame = +1 Query: 190 DVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGG 369 D + ++S D+T++ W E+V +TL GH + + ++ + +VSG Sbjct: 365 DKYIVSASGDRTIKVWNT---STCEFV--RTLNGHKRGIACL-------QYRDRLVVSGS 412 Query: 370 MDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSSMD 498 D + LW++ G ++GH V + DN I+S + D Sbjct: 413 SDNTIRLWDIECGACLRVLEGHEELVRCIRF-DNKRIVSGAYD 454 Score = 38.1 bits (87), Expect = 0.013 Identities = 27/100 (27%), Positives = 43/100 (43%) Frame = +1 Query: 199 VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDT 378 + T S+D+++ W + L + LVGH + V + F + IVS D Sbjct: 325 MVTCSKDRSIAVWDM--ASATDITLRRVLVGHRAAVNVV-------DFDDKYIVSASGDR 375 Query: 379 QVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSSMD 498 + +WN T E T+ GH + L D ++S S D Sbjct: 376 TIKVWNTSTCEFVRTLNGHKRGIACLQYRDR-LVVSGSSD 414 Score = 29.6 bits (65), Expect = 4.7 Identities = 38/129 (29%), Positives = 53/129 (41%), Gaps = 11/129 (8%) Frame = +1 Query: 145 LHGHEDDVRGICICG--DVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMV 318 L+GH+ RGI D V + S D T+R W + L GH V + Sbjct: 391 LNGHK---RGIACLQYRDRLVVSGSSDNTIRLWDIECG-----ACLRVLEGHEELVRCI- 441 Query: 319 WAPPSDRFPEGAIVSGGMDTQVLLWNLHTG----EVAG-----TMKGHTSQVTGLAIDDN 471 RF IVSG D ++ +W+L AG T+ H+ +V L D+ Sbjct: 442 ------RFDNKRIVSGAYDGKIKVWDLVAALDPRAPAGTLCLRTLVEHSGRVFRLQFDE- 494 Query: 472 GDIISSSMD 498 I+SSS D Sbjct: 495 FQIVSSSHD 503
>WDR48_CHICK (Q5F3K4) WD-repeat protein 48| Length = 678 Score = 45.4 bits (106), Expect = 8e-05 Identities = 25/96 (26%), Positives = 46/96 (47%) Frame = +1 Query: 205 TSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDTQV 384 T+ RD +R W+ + K+ Y+ S + H+ +V +V ++S DT V Sbjct: 47 TAGRDSIIRIWSVNQHKQDPYIAS--MEHHTDWVNDIVLCCNGK-----TLISASSDTTV 99 Query: 385 LLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSS 492 +WN H G T++ H V LA + ++++S+ Sbjct: 100 KVWNAHKGFCMSTLRTHKDYVKALAYAKDKELVASA 135 Score = 30.4 bits (67), Expect = 2.8 Identities = 38/174 (21%), Positives = 63/174 (36%), Gaps = 54/174 (31%) Frame = +1 Query: 139 AQLHGHEDDVRGICIC--GDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGP 312 A + H D V I +C G ++ SS D TV+ W H + + +S TL H +V Sbjct: 69 ASMEHHTDWVNDIVLCCNGKTLISASS-DTTVKVWNAH----KGFCMS-TLRTHKDYVKA 122 Query: 313 MVWAPPSDRFPEGAIVSGGMDTQVLLWNLH-------------TGEVAGT---------- 423 + +A + + S G+D Q+ LW+++ T ++G Sbjct: 123 LAYAKDKE-----LVASAGLDRQIFLWDVNTLTALTASNNTVTTSSLSGNKDSIYSLAMN 177 Query: 424 ----------------------------MKGHTSQVTGLAIDDNG-DIISSSMD 498 +KGHT V L ++ +G +S S D Sbjct: 178 QMGTVIVSGSTEKVLRVWDPRTCAKLMKLKGHTDNVKALLLNRDGTQCLSGSSD 231
>WDR48_MACFA (Q4R2Z6) WD-repeat protein 48| Length = 622 Score = 45.4 bits (106), Expect = 8e-05 Identities = 25/96 (26%), Positives = 46/96 (47%) Frame = +1 Query: 205 TSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDTQV 384 T+ RD +R W+ + K+ Y+ S + H+ +V +V ++S DT V Sbjct: 47 TAGRDSIIRIWSVNQHKQDPYIAS--MEHHTDWVNDIVLCCNGK-----TLISASSDTTV 99 Query: 385 LLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSS 492 +WN H G T++ H V LA + ++++S+ Sbjct: 100 KVWNAHKGFCMSTLRTHKDYVKALAYAKDKELVASA 135
>WDR48_MOUSE (Q8BH57) WD-repeat protein 48| Length = 676 Score = 45.4 bits (106), Expect = 8e-05 Identities = 25/96 (26%), Positives = 46/96 (47%) Frame = +1 Query: 205 TSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDTQV 384 T+ RD +R W+ + K+ Y+ S + H+ +V +V ++S DT V Sbjct: 47 TAGRDSIIRIWSVNQHKQDPYIAS--MEHHTDWVNDVVLCCNGK-----TLISASSDTTV 99 Query: 385 LLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSS 492 +WN H G T++ H V LA + ++++S+ Sbjct: 100 KVWNAHKGFCMSTLRTHKDYVKALAYAKDKELVASA 135
>GBLP_CAEEL (Q21215) Guanine nucleotide-binding protein beta subunit 2-like 1| Length = 324 Score = 45.1 bits (105), Expect = 1e-04 Identities = 33/117 (28%), Positives = 55/117 (47%), Gaps = 1/117 (0%) Frame = +1 Query: 142 QLHGHEDDVRGICICGDVG-VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMV 318 Q H DV + D + + SRDK+++ W + K Y ++ H+ +V + Sbjct: 105 QFISHTKDVLSVAFSADNRQIVSGSRDKSIKLWNTLAQCK--YTITDDC--HTDWVSTVR 160 Query: 319 WAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISS 489 ++P S+R P IVS G D V +WNL + GHT V + + +G + +S Sbjct: 161 FSP-SNRDP--VIVSAGWDKVVKVWNLGNCRLKTNHIGHTGYVNTVTVSPDGSLCAS 214 Score = 39.7 bits (91), Expect = 0.005 Identities = 32/105 (30%), Positives = 46/105 (43%), Gaps = 5/105 (4%) Frame = +1 Query: 199 VATSSRDKTVRFW-TQHPEKKREYVLSK---TLVGHSSFVGPMVWAPPSDRFPEGAIVSG 366 V +SSRDKT+ W E + + +L GH+ FV +V + +SG Sbjct: 32 VLSSSRDKTILVWDVDSVAPVDEGPIGRPVRSLTGHNHFVSDVVISSDGQ-----FALSG 86 Query: 367 GMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAID-DNGDIISSSMD 498 D + LW+L+ G HT V +A DN I+S S D Sbjct: 87 SWDKTLRLWDLNQGVSTRQFISHTKDVLSVAFSADNRQIVSGSRD 131 Score = 34.3 bits (77), Expect = 0.19 Identities = 22/83 (26%), Positives = 41/83 (49%), Gaps = 1/83 (1%) Frame = +1 Query: 190 DVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAI-VSG 366 D + ++ DK V+ W + L +GH+ +V + +P +G++ SG Sbjct: 167 DPVIVSAGWDKVVKVWNLGNCR-----LKTNHIGHTGYVNTVTVSP------DGSLCASG 215 Query: 367 GMDTQVLLWNLHTGEVAGTMKGH 435 G D Q +LW+L+ G+ T+ G+ Sbjct: 216 GKDGQAMLWDLNEGKHLYTLPGN 238
>SPG16_HUMAN (Q8N0X2) Sperm-associated antigen 16 protein (PF20 protein homolog)| Length = 631 Score = 45.1 bits (105), Expect = 1e-04 Identities = 30/106 (28%), Positives = 50/106 (47%) Frame = +1 Query: 184 CGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVS 363 CG+ VA+SS DKT + W + E+ R TL GH+ V + + P S+ +++ Sbjct: 447 CGNF-VASSSLDKTSKIWDVNSERCR-----CTLYGHTDSVNSIEFFPFSN-----TLLT 495 Query: 364 GGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSSMDC 501 D + +W+ TG ++ GH + D G +I+S C Sbjct: 496 SSADKTLSIWDARTGICEQSLYGHMHSINDAIFDPRGHMIASCDAC 541 Score = 35.0 bits (79), Expect = 0.11 Identities = 22/68 (32%), Positives = 34/68 (50%) Frame = +1 Query: 289 GHSSFVGPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDD 468 GH+ ++ + P D+ A SG DT V LW+L TG+ T +GH+ V Sbjct: 392 GHTDWLSDCCFHPSGDKL---ATSSG--DTTVKLWDLCTGDCILTFEGHSRAVWSCTWHS 446 Query: 469 NGDIISSS 492 G+ ++SS Sbjct: 447 CGNFVASS 454 Score = 33.9 bits (76), Expect = 0.25 Identities = 32/119 (26%), Positives = 51/119 (42%), Gaps = 3/119 (2%) Frame = +1 Query: 151 GHEDDVRGICI--CGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWA 324 GH D + C GD +ATSS D TV+ W + +L T GHS V W Sbjct: 392 GHTDWLSDCCFHPSGDK-LATSSGDTTVKLWDL---CTGDCIL--TFEGHSRAVWSCTWH 445 Query: 325 PPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLA-IDDNGDIISSSMD 498 + + S +D +W++++ T+ GHT V + + +++SS D Sbjct: 446 SCGN-----FVASSSLDKTSKIWDVNSERCRCTLYGHTDSVNSIEFFPFSNTLLTSSAD 499
>WDR48_BRARE (Q6PFM9) WD-repeat protein 48| Length = 677 Score = 45.1 bits (105), Expect = 1e-04 Identities = 24/96 (25%), Positives = 46/96 (47%) Frame = +1 Query: 205 TSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDTQV 384 T+ RD +R W+ + K+ Y+ S + H+ +V ++ ++S DT V Sbjct: 47 TAGRDSIIRIWSVNQHKQDPYIAS--MEHHTDWVNDIILCCNGK-----TLISASSDTTV 99 Query: 385 LLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSS 492 +WN H G T++ H V LA + ++++S+ Sbjct: 100 KVWNAHKGFCMSTLRTHKDYVKALAYAKDKELVASA 135 Score = 30.4 bits (67), Expect = 2.8 Identities = 38/174 (21%), Positives = 63/174 (36%), Gaps = 54/174 (31%) Frame = +1 Query: 139 AQLHGHEDDVRGICIC--GDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGP 312 A + H D V I +C G ++ SS D TV+ W H + + +S TL H +V Sbjct: 69 ASMEHHTDWVNDIILCCNGKTLISASS-DTTVKVWNAH----KGFCMS-TLRTHKDYVKA 122 Query: 313 MVWAPPSDRFPEGAIVSGGMDTQVLLWNLH-------------TGEVAGT---------- 423 + +A + + S G+D Q+ LW+++ T ++G Sbjct: 123 LAYAKDKE-----LVASAGLDRQIFLWDVNTLTALTASNNTVTTSSLSGNKDSIYSLAMN 177 Query: 424 ----------------------------MKGHTSQVTGLAIDDNG-DIISSSMD 498 +KGHT V L ++ +G +S S D Sbjct: 178 QTGTVIISGSTEKVLRVWDPRTCAKLMKLKGHTDNVKSLLLNRDGTQCLSGSSD 231
>PRP19_CHICK (Q5ZMA2) Pre-mRNA-splicing factor 19 (PRP19/PSO4 homolog)| Length = 505 Score = 44.7 bits (104), Expect = 1e-04 Identities = 29/100 (29%), Positives = 46/100 (46%) Frame = +1 Query: 199 VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDT 378 + T DK V + +K E +L+ TL GHS V +V+ P D + S D Sbjct: 238 ILTGGADKNVIVF----DKSSEQILA-TLKGHSKKVTSVVFHPSQD-----LVFSASPDA 287 Query: 379 QVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSSMD 498 + +W++ ++ H VTGL++ GD + SS D Sbjct: 288 TIRIWSVPNASCVQVVRAHEGSVTGLSLHATGDYLLSSSD 327 Score = 37.4 bits (85), Expect = 0.023 Identities = 16/53 (30%), Positives = 30/53 (56%), Gaps = 1/53 (1%) Frame = +1 Query: 343 PEGAIV-SGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSSMD 498 P+G I +G MD+Q+ +W+L GH+ +T +A +NG ++++ D Sbjct: 361 PDGLIFGTGTMDSQIKIWDLKERTNVANFPGHSGPITSIAFSENGYYLATAAD 413 Score = 35.8 bits (81), Expect = 0.066 Identities = 16/55 (29%), Positives = 33/55 (60%) Frame = +1 Query: 328 PSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSS 492 PSD I++GG D V++++ + ++ T+KGH+ +VT + + D++ S+ Sbjct: 232 PSDT---NKILTGGADKNVIVFDKSSEQILATLKGHSKKVTSVVFHPSQDLVFSA 283
>FBW1A_HUMAN (Q9Y297) F-box/WD-repeat protein 1A (F-box and WD-repeats protein| beta-TrCP) (E3RSIkappaB) (pIkappaBalpha-E3 receptor subunit) Length = 605 Score = 44.7 bits (104), Expect = 1e-04 Identities = 31/125 (24%), Positives = 59/125 (47%), Gaps = 2/125 (1%) Frame = +1 Query: 130 HLSAQLHGHEDDVRGI-CI-CGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSF 303 H ++H + +G+ C+ D + + RD T++ W K + L GH+ Sbjct: 291 HSLQRIHCRSETSKGVYCLQYDDQKIVSGLRDNTIKIWD-----KNTLECKRILTGHTGS 345 Query: 304 VGPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDII 483 V + ++ E I++G D+ V +W+++TGE+ T+ H V L +NG ++ Sbjct: 346 VLCL-------QYDERVIITGSSDSTVRVWDVNTGEMLNTLIHHCEAVLHLRF-NNGMMV 397 Query: 484 SSSMD 498 + S D Sbjct: 398 TCSKD 402 Score = 38.1 bits (87), Expect = 0.013 Identities = 26/103 (25%), Positives = 48/103 (46%) Frame = +1 Query: 190 DVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGG 369 D + ++S D+T++ W E+V +TL GH + + ++ + +VSG Sbjct: 436 DKYIVSASGDRTIKVWNT---STCEFV--RTLNGHKRGIACL-------QYRDRLVVSGS 483 Query: 370 MDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSSMD 498 D + LW++ G ++GH V + DN I+S + D Sbjct: 484 SDNTIRLWDIECGACLRVLEGHEELVRCIRF-DNKRIVSGAYD 525 Score = 38.1 bits (87), Expect = 0.013 Identities = 27/100 (27%), Positives = 43/100 (43%) Frame = +1 Query: 199 VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDT 378 + T S+D+++ W + L + LVGH + V + F + IVS D Sbjct: 396 MVTCSKDRSIAVWDM--ASPTDITLRRVLVGHRAAVNVV-------DFDDKYIVSASGDR 446 Query: 379 QVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSSMD 498 + +WN T E T+ GH + L D ++S S D Sbjct: 447 TIKVWNTSTCEFVRTLNGHKRGIACLQYRDR-LVVSGSSD 485 Score = 29.6 bits (65), Expect = 4.7 Identities = 38/129 (29%), Positives = 53/129 (41%), Gaps = 11/129 (8%) Frame = +1 Query: 145 LHGHEDDVRGICICG--DVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMV 318 L+GH+ RGI D V + S D T+R W + L GH V + Sbjct: 462 LNGHK---RGIACLQYRDRLVVSGSSDNTIRLWDIECG-----ACLRVLEGHEELVRCI- 512 Query: 319 WAPPSDRFPEGAIVSGGMDTQVLLWNLHTG----EVAG-----TMKGHTSQVTGLAIDDN 471 RF IVSG D ++ +W+L AG T+ H+ +V L D+ Sbjct: 513 ------RFDNKRIVSGAYDGKIKVWDLVAALDPRAPAGTLCLRTLVEHSGRVFRLQFDE- 565 Query: 472 GDIISSSMD 498 I+SSS D Sbjct: 566 FQIVSSSHD 574
>SWD3_SCHPO (O43017) Set1 complex component swd3 (Set1C component swd3)| (COMPASS component swd3) (Complex proteins associated with set1 protein swd3) Length = 380 Score = 44.7 bits (104), Expect = 1e-04 Identities = 32/123 (26%), Positives = 58/123 (47%), Gaps = 1/123 (0%) Frame = +1 Query: 127 YHLSAQLHGHEDDVRGI-CICGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSF 303 + L L GH + + G +A++S DKT+R W +KR V + L GH+++ Sbjct: 86 FRLECTLFGHYRGISQVKWATGSKYLASASDDKTIRIWDF---EKRCSV--RCLKGHTNY 140 Query: 304 VGPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDII 483 V + + P +VSG D V +WNL G + H+ + ++I +G + Sbjct: 141 VSSIDFNPLGT-----LLVSGSWDETVRIWNLQDGTCLRMLPAHSEPIISVSISADGTLC 195 Query: 484 SSS 492 +++ Sbjct: 196 ATA 198 Score = 42.0 bits (97), Expect = 0.001 Identities = 30/116 (25%), Positives = 51/116 (43%), Gaps = 1/116 (0%) Frame = +1 Query: 145 LHGHEDDVRGICICGDVG-VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVW 321 L GHE V + + + +ATSS D T++ W+ + L TL GH + + W Sbjct: 50 LFGHEKSVTCVSVSPNKRWIATSSSDGTIKIWS-----ALTFRLECTLFGHYRGISQVKW 104 Query: 322 APPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISS 489 A S + S D + +W+ +KGHT+ V+ + + G ++ S Sbjct: 105 ATGSK-----YLASASDDKTIRIWDFEKRCSVRCLKGHTNYVSSIDFNPLGTLLVS 155
>YCW2_YEAST (P25382) Hypothetical WD-repeat protein YCR072C| Length = 515 Score = 44.3 bits (103), Expect = 2e-04 Identities = 36/124 (29%), Positives = 56/124 (45%), Gaps = 6/124 (4%) Frame = +1 Query: 145 LHGHEDDVRGICIC----GDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGP 312 L GH + V +C+ G+V +AT S D T+R W + K L L GHS ++ Sbjct: 182 LKGHYNWV--LCVSWSPDGEV-IATGSMDNTIRLW----DPKSGQCLGDALRGHSKWITS 234 Query: 313 MVWAPPSDRFP--EGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIIS 486 + W P P + + S D + +W+ + TM GHT+ V+ + G + S Sbjct: 235 LSWEPIHLVKPGSKPRLASSSKDGTIKIWDTVSRVCQYTMSGHTNSVSCVKWGGQGLLYS 294 Query: 487 SSMD 498 S D Sbjct: 295 GSHD 298 Score = 35.8 bits (81), Expect = 0.066 Identities = 25/87 (28%), Positives = 41/87 (47%) Frame = +1 Query: 199 VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDT 378 + T+S D T+ W +P K + + T GH V + ++P R+ IVS D Sbjct: 374 MVTASDDYTMFLW--NPLKSTKPIARMT--GHQKLVNHVAFSPDG-RY----IVSASFDN 424 Query: 379 QVLLWNLHTGEVAGTMKGHTSQVTGLA 459 + LW+ G+ T +GH + V +A Sbjct: 425 SIKLWDGRDGKFISTFRGHVASVYQVA 451 Score = 33.5 bits (75), Expect = 0.33 Identities = 21/76 (27%), Positives = 38/76 (50%), Gaps = 1/76 (1%) Frame = +1 Query: 274 SKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTG 453 S + GH S + +AP + +V+G D +W+ T T+KGH + V Sbjct: 136 SSAIAGHGSTILCSAFAPHTS----SRMVTGAGDNTARIWDCDTQTPMHTLKGHYNWVLC 191 Query: 454 LAIDDNGDIISS-SMD 498 ++ +G++I++ SMD Sbjct: 192 VSWSPDGEVIATGSMD 207 Score = 32.3 bits (72), Expect = 0.73 Identities = 23/104 (22%), Positives = 46/104 (44%), Gaps = 1/104 (0%) Frame = +1 Query: 139 AQLHGHEDDVRGICICGDVG-VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPM 315 A++ GH+ V + D + ++S D +++ W K T GH + V + Sbjct: 396 ARMTGHQKLVNHVAFSPDGRYIVSASFDNSIKLWDGRDGK-----FISTFRGHVASVYQV 450 Query: 316 VWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQV 447 W+ +VS DT + +W++ T +++ + GH +V Sbjct: 451 AWSSDCR-----LLVSCSKDTTLKVWDVRTRKLSVDLPGHKDEV 489
>GBLP_HYDAT (Q25189) Guanine nucleotide-binding protein beta subunit-like| protein (Receptor of activated protein kinase C) (RACK) Length = 317 Score = 43.9 bits (102), Expect = 2e-04 Identities = 31/117 (26%), Positives = 52/117 (44%), Gaps = 1/117 (0%) Frame = +1 Query: 142 QLHGHEDDVRGICICGDVG-VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMV 318 Q GH DV + D + + SRD T++ W + K Y + HS +V + Sbjct: 100 QFVGHTKDVLSVAFSADNRQIVSGSRDNTIKLWNTLGQCK--YTIQDE--SHSEWVSCVR 155 Query: 319 WAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISS 489 ++P + IVS G D V +WNL ++ GHT + + + +G + +S Sbjct: 156 FSPNTQN---PIIVSCGWDKMVKVWNLTNCKLKTNHFGHTGYLNAVTVSPDGSLCAS 209 Score = 43.9 bits (102), Expect = 2e-04 Identities = 31/102 (30%), Positives = 46/102 (45%), Gaps = 2/102 (1%) Frame = +1 Query: 199 VATSSRDKTVRFWTQHPEKKREYVL-SKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMD 375 + ++SRDKT+ W + + Y K L GH+ FV +V + +S D Sbjct: 30 ILSASRDKTLIQWQLTRDDQTNYGFPKKCLTGHNHFVSDVVLSSDGQ-----FALSCSWD 84 Query: 376 TQVLLWNLHTGEVAGTMKGHTSQVTGLAID-DNGDIISSSMD 498 + LW+L+ G GHT V +A DN I+S S D Sbjct: 85 KTLRLWDLNQGITTKQFVGHTKDVLSVAFSADNRQIVSGSRD 126
>UTP13_SCHPO (Q9USN3) Probable U3 small nucleolar RNA-associated protein 13 (U3| snoRNA-associated protein 13) Length = 777 Score = 43.9 bits (102), Expect = 2e-04 Identities = 31/119 (26%), Positives = 54/119 (45%), Gaps = 4/119 (3%) Frame = +1 Query: 145 LHGHEDDVRGICICG----DVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGP 312 L GH RG+ C +A+ S D+T+R W ++ +TL GH+ + Sbjct: 503 LRGHR---RGVWACSFNPFSRQLASGSGDRTIRIWNVDTQQ-----CVQTLEGHTGAILK 554 Query: 313 MVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISS 489 +++ + +VS D V +W+L +GE T+ H +V LA +G ++ S Sbjct: 555 LIYISQGTQ-----VVSAAADGLVKVWSLSSGECVATLDNHEDRVWALASRFDGSLLVS 608 Score = 43.9 bits (102), Expect = 2e-04 Identities = 32/120 (26%), Positives = 56/120 (46%), Gaps = 2/120 (1%) Frame = +1 Query: 145 LHGHEDDVRGICICGDVGV-ATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVW 321 + H+ DV I + D + A++S+DKT++ W + + L GH V W Sbjct: 461 IKAHDRDVNAIQVSKDGRIIASASQDKTIKLWDSSTGE-----VVGVLRGHRRGV----W 511 Query: 322 APPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLA-IDDNGDIISSSMD 498 A + F + SG D + +WN+ T + T++GHT + L I ++S++ D Sbjct: 512 ACSFNPFSR-QLASGSGDRTIRIWNVDTQQCVQTLEGHTGAILKLIYISQGTQVVSAAAD 570 Score = 36.2 bits (82), Expect = 0.051 Identities = 24/101 (23%), Positives = 47/101 (46%), Gaps = 1/101 (0%) Frame = +1 Query: 199 VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDT 378 +AT + V+ W + YV + + GH + + + + + + SG D+ Sbjct: 118 LATGGAEGLVKVW----DIAGAYV-THSFRGHGGVISALCFGKHQNTW---VLASGADDS 169 Query: 379 QVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGD-IISSSMD 498 +V LW+L++ +GH+S + GL + G ++S S D Sbjct: 170 RVRLWDLNSSRSMAVFEGHSSVIRGLTFEPTGSFLLSGSRD 210
>PRP46_EMENI (Q5BE22) Pre-mRNA-splicing factor prp46 (Pre-mRNA-processing| protein 46) Length = 452 Score = 43.9 bits (102), Expect = 2e-04 Identities = 25/74 (33%), Positives = 37/74 (50%) Frame = +1 Query: 241 QHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAG 420 Q PE + L + + GH +V + P ++ F SG D + +WNL TG + Sbjct: 125 QPPEWHAPWKLMRVISGHLGWVRSLAVEPNNEWF-----ASGAGDRTIKIWNLATGALRL 179 Query: 421 TMKGHTSQVTGLAI 462 T+ GH S V GLA+ Sbjct: 180 TLTGHISTVRGLAV 193 Score = 40.0 bits (92), Expect = 0.004 Identities = 36/129 (27%), Positives = 56/129 (43%), Gaps = 1/129 (0%) Frame = +1 Query: 100 RRPAPLMAAYHLSAQLHGHEDDVRGICI-CGDVGVATSSRDKTVRFWTQHPEKKREYVLS 276 ++P A + L + GH VR + + + A+ + D+T++ W L Sbjct: 124 QQPPEWHAPWKLMRVISGHLGWVRSLAVEPNNEWFASGAGDRTIKIWNLATG-----ALR 178 Query: 277 KTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGL 456 TL GH S V + +P R P + S G D V W+L T +V GH S V L Sbjct: 179 LTLTGHISTVRGLAVSP---RHPY--LFSCGEDKMVKCWDLETNKVIRHYHGHLSGVYTL 233 Query: 457 AIDDNGDII 483 A+ D++ Sbjct: 234 ALHPRLDLL 242 Score = 35.8 bits (81), Expect = 0.066 Identities = 33/129 (25%), Positives = 52/129 (40%), Gaps = 2/129 (1%) Frame = +1 Query: 118 MAAYHLSAQLHGHEDDVRGICICGDVGVATS-SRDKTVRFWTQHPEKKREYVLSKTLVGH 294 +A L L GH VRG+ + S DK V+ W K + + GH Sbjct: 172 LATGALRLTLTGHISTVRGLAVSPRHPYLFSCGEDKMVKCWDLETNK-----VIRHYHGH 226 Query: 295 SSFVGPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDD-N 471 S V + P D +V+GG D +W++ T + GHT V + + + Sbjct: 227 LSGVYTLALHPRLD-----LLVTGGRDGVARVWDMRTRSNIHVLSGHTGTVADVQCQEAD 281 Query: 472 GDIISSSMD 498 +I+ S+D Sbjct: 282 PQVITGSLD 290
>TAF5_SCHPO (O13282) Transcription initiation factor TFIID subunit 5| (Transcription initiation factor TFIID 72 kDa subunit) (TAFII-72) Length = 643 Score = 43.9 bits (102), Expect = 2e-04 Identities = 29/97 (29%), Positives = 46/97 (47%) Frame = +1 Query: 202 ATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDTQ 381 AT+S D+T + W+ Y L + GH S V + + P S +++G D Sbjct: 437 ATASHDQTAQLWSCD----HIYPL-RVFAGHLSDVDCVTFHPNS-----AYVLTGSSDKT 486 Query: 382 VLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSS 492 LW++H G GHT VT +AI +G ++S+ Sbjct: 487 CRLWDVHRGHSVRVFNGHTQPVTAVAIAPDGHTMASA 523 Score = 38.5 bits (88), Expect = 0.010 Identities = 27/102 (26%), Positives = 42/102 (41%), Gaps = 1/102 (0%) Frame = +1 Query: 199 VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDT 378 V T S DKT R W H + GH+ V + AP + S + Sbjct: 478 VLTGSSDKTCRLWDVHRGHS-----VRVFNGHTQPVTAVAIAPDGH-----TMASADSEG 527 Query: 379 QVLLWNLHTGEVAGTMKGHTSQVTGLAID-DNGDIISSSMDC 501 + LW++ TG TM+GH + L+ ++ ++S DC Sbjct: 528 LIHLWDIGTGRRIKTMRGHRGNIYSLSFSRESTVLVSGGSDC 569
>WDR12_RAT (P61480) WD-repeat protein 12| Length = 423 Score = 43.9 bits (102), Expect = 2e-04 Identities = 26/101 (25%), Positives = 49/101 (48%), Gaps = 1/101 (0%) Frame = +1 Query: 199 VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDT 378 +A+ S D+ +R W P K ++S +L H+ +V + W+P D+ ++SG +D Sbjct: 312 LASGSTDRHIRLWD--PRTKDGSLVSLSLTSHTGWVTSVKWSPTHDQ----QLISGSLDN 365 Query: 379 QVLLWNLHTGEV-AGTMKGHTSQVTGLAIDDNGDIISSSMD 498 V LW+ + + + H +V + D G ++S D Sbjct: 366 MVKLWDTRSCKAPLYDLAAHEDKVLSVDWTDTGLLLSGGAD 406 Score = 38.9 bits (89), Expect = 0.008 Identities = 25/96 (26%), Positives = 42/96 (43%), Gaps = 4/96 (4%) Frame = +1 Query: 199 VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDT 378 + + S DKT R W+ + T+VGH+ V + W +++ MD Sbjct: 114 ILSGSYDKTSRIWSLEGKS------IMTIVGHTDVVKDVAWVKKDSL--SCLLLTASMDQ 165 Query: 379 QVLLW--NLHTGEVAGT--MKGHTSQVTGLAIDDNG 474 +LLW N+ +V +GH V +A+D +G Sbjct: 166 TILLWEWNIERNKVKALHCCRGHAGSVDAIAVDSSG 201 Score = 33.5 bits (75), Expect = 0.33 Identities = 33/123 (26%), Positives = 52/123 (42%), Gaps = 5/123 (4%) Frame = +1 Query: 145 LHGHEDDVRGICICGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWA 324 L GH + + + V ++S D TVR W L TL G+ F + ++ Sbjct: 253 LSGHTEAISSVLWSDADEVCSASWDHTVRVWDVESGG-----LKSTLTGNKVF-NCISYS 306 Query: 325 PPSDRFPEGAIVSGGMDTQVLLWNLHTGE---VAGTMKGHTSQVTGLAIDDNGD--IISS 489 P R + SG D + LW+ T + V+ ++ HT VT + D +IS Sbjct: 307 PLCKR-----LASGSTDRHIRLWDPRTKDGSLVSLSLTSHTGWVTSVKWSPTHDQQLISG 361 Query: 490 SMD 498 S+D Sbjct: 362 SLD 364
>SRW1_SCHPO (O13286) WD-repeat-containing protein srw1 (Suppressor of rad/wee1)| Length = 556 Score = 43.5 bits (101), Expect = 3e-04 Identities = 33/111 (29%), Positives = 54/111 (48%), Gaps = 1/111 (0%) Frame = +1 Query: 169 RGICICGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPE 348 RGI G + D+T++ W +R +L G S V ++W+ ++ F Sbjct: 429 RGILASGG-----GTADRTIKLWNT----QRGSMLHNIDTG--SQVCNLLWSKQTNEFIS 477 Query: 349 GAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGD-IISSSMD 498 G M+ +V LWN + GT+KGHT +V LA+ NG+ I++ + D Sbjct: 478 ---THGFMENEVALWNYPSVSRVGTLKGHTDRVLYLAMSPNGENIVTGAAD 525
>LIS1_RAT (P63004) Platelet-activating factor acetylhydrolase IB alpha| subunit (PAF acetylhydrolase 45 kDa subunit) (PAF-AH 45 kDa subunit) (PAF-AH alpha) (PAFAH alpha) (Lissencephaly-1 protein) (LIS-1) Length = 409 Score = 43.5 bits (101), Expect = 3e-04 Identities = 26/85 (30%), Positives = 42/85 (49%) Frame = +1 Query: 235 WTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEV 414 W P +K Y LS GH S V +++ P +VS D + +W+ TG+ Sbjct: 93 WIPRPPEK--YALS----GHRSPVTRVIFHPVFS-----VMVSASEDATIKVWDYETGDF 141 Query: 415 AGTMKGHTSQVTGLAIDDNGDIISS 489 T+KGHT V ++ D +G +++S Sbjct: 142 ERTLKGHTDSVQDISFDHSGKLLAS 166 Score = 42.0 bits (97), Expect = 0.001 Identities = 32/117 (27%), Positives = 51/117 (43%), Gaps = 2/117 (1%) Frame = +1 Query: 145 LHGHEDDVRGICI--CGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMV 318 L GH D V+ I G + +A+ S D T++ W + + +T+ GH V + Sbjct: 145 LKGHTDSVQDISFDHSGKL-LASCSADMTIKLWDF-----QGFECIRTMHGHDHNVSSVA 198 Query: 319 WAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISS 489 P D IVS D + +W + TG T GH V + + +G +I+S Sbjct: 199 IMPNGDH-----IVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIAS 250 Score = 40.8 bits (94), Expect = 0.002 Identities = 30/115 (26%), Positives = 46/115 (40%), Gaps = 15/115 (13%) Frame = +1 Query: 199 VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRF------------ 342 +A+ S D+TVR W ++ + L H V + WAP S Sbjct: 248 IASCSNDQTVRVWVVATKECKA-----ELREHEHVVECISWAPESSYSSISEATGSETKK 302 Query: 343 ---PEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSSMD 498 P ++SG D + +W++ TG T+ GH + V G+ G I S D Sbjct: 303 SGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCAD 357 Score = 38.9 bits (89), Expect = 0.008 Identities = 34/120 (28%), Positives = 48/120 (40%), Gaps = 2/120 (1%) Frame = +1 Query: 145 LHGHEDDVRGICICGDVGVATS-SRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVW 321 L GH V + V S S D T++ W +TL GH+ V + + Sbjct: 103 LSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGD-----FERTLKGHTDSVQDISF 157 Query: 322 APPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGD-IISSSMD 498 + S D + LW+ E TM GH V+ +AI NGD I+S+S D Sbjct: 158 DHSGK-----LLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRD 212
>LIS1_PANTR (Q5IS43) Platelet-activating factor acetylhydrolase IB alpha| subunit (PAF acetylhydrolase 45 kDa subunit) (PAF-AH 45 kDa subunit) (PAF-AH alpha) (PAFAH alpha) (Lissencephaly-1 protein) (LIS-1) Length = 409 Score = 43.5 bits (101), Expect = 3e-04 Identities = 26/85 (30%), Positives = 42/85 (49%) Frame = +1 Query: 235 WTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEV 414 W P +K Y LS GH S V +++ P +VS D + +W+ TG+ Sbjct: 93 WIPRPPEK--YALS----GHRSPVTRVIFHPVFS-----VMVSASEDATIKVWDYETGDF 141 Query: 415 AGTMKGHTSQVTGLAIDDNGDIISS 489 T+KGHT V ++ D +G +++S Sbjct: 142 ERTLKGHTDSVQDISFDHSGKLLAS 166 Score = 42.0 bits (97), Expect = 0.001 Identities = 32/117 (27%), Positives = 51/117 (43%), Gaps = 2/117 (1%) Frame = +1 Query: 145 LHGHEDDVRGICI--CGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMV 318 L GH D V+ I G + +A+ S D T++ W + + +T+ GH V + Sbjct: 145 LKGHTDSVQDISFDHSGKL-LASCSADMTIKLWDF-----QGFECIRTMHGHDHNVSSVA 198 Query: 319 WAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISS 489 P D IVS D + +W + TG T GH V + + +G +I+S Sbjct: 199 IMPNGDH-----IVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIAS 250 Score = 40.8 bits (94), Expect = 0.002 Identities = 30/115 (26%), Positives = 46/115 (40%), Gaps = 15/115 (13%) Frame = +1 Query: 199 VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRF------------ 342 +A+ S D+TVR W ++ + L H V + WAP S Sbjct: 248 IASCSNDQTVRVWVVATKECKA-----ELREHEHVVECISWAPESSYSSISEATGSETKK 302 Query: 343 ---PEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSSMD 498 P ++SG D + +W++ TG T+ GH + V G+ G I S D Sbjct: 303 SGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCAD 357 Score = 38.9 bits (89), Expect = 0.008 Identities = 34/120 (28%), Positives = 48/120 (40%), Gaps = 2/120 (1%) Frame = +1 Query: 145 LHGHEDDVRGICICGDVGVATS-SRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVW 321 L GH V + V S S D T++ W +TL GH+ V + + Sbjct: 103 LSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGD-----FERTLKGHTDSVQDISF 157 Query: 322 APPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGD-IISSSMD 498 + S D + LW+ E TM GH V+ +AI NGD I+S+S D Sbjct: 158 DHSGK-----LLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRD 212
>LIS1_MOUSE (P63005) Platelet-activating factor acetylhydrolase IB alpha| subunit (PAF acetylhydrolase 45 kDa subunit) (PAF-AH 45 kDa subunit) (PAF-AH alpha) (PAFAH alpha) (Lissencephaly-1 protein) (LIS-1) Length = 409 Score = 43.5 bits (101), Expect = 3e-04 Identities = 26/85 (30%), Positives = 42/85 (49%) Frame = +1 Query: 235 WTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEV 414 W P +K Y LS GH S V +++ P +VS D + +W+ TG+ Sbjct: 93 WIPRPPEK--YALS----GHRSPVTRVIFHPVFS-----VMVSASEDATIKVWDYETGDF 141 Query: 415 AGTMKGHTSQVTGLAIDDNGDIISS 489 T+KGHT V ++ D +G +++S Sbjct: 142 ERTLKGHTDSVQDISFDHSGKLLAS 166 Score = 42.0 bits (97), Expect = 0.001 Identities = 32/117 (27%), Positives = 51/117 (43%), Gaps = 2/117 (1%) Frame = +1 Query: 145 LHGHEDDVRGICI--CGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMV 318 L GH D V+ I G + +A+ S D T++ W + + +T+ GH V + Sbjct: 145 LKGHTDSVQDISFDHSGKL-LASCSADMTIKLWDF-----QGFECIRTMHGHDHNVSSVA 198 Query: 319 WAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISS 489 P D IVS D + +W + TG T GH V + + +G +I+S Sbjct: 199 IMPNGDH-----IVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIAS 250 Score = 40.8 bits (94), Expect = 0.002 Identities = 30/115 (26%), Positives = 46/115 (40%), Gaps = 15/115 (13%) Frame = +1 Query: 199 VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRF------------ 342 +A+ S D+TVR W ++ + L H V + WAP S Sbjct: 248 IASCSNDQTVRVWVVATKECKA-----ELREHEHVVECISWAPESSYSSISEATGSETKK 302 Query: 343 ---PEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSSMD 498 P ++SG D + +W++ TG T+ GH + V G+ G I S D Sbjct: 303 SGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCAD 357 Score = 38.9 bits (89), Expect = 0.008 Identities = 34/120 (28%), Positives = 48/120 (40%), Gaps = 2/120 (1%) Frame = +1 Query: 145 LHGHEDDVRGICICGDVGVATS-SRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVW 321 L GH V + V S S D T++ W +TL GH+ V + + Sbjct: 103 LSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGD-----FERTLKGHTDSVQDISF 157 Query: 322 APPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGD-IISSSMD 498 + S D + LW+ E TM GH V+ +AI NGD I+S+S D Sbjct: 158 DHSGK-----LLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRD 212
>LIS1_MACFA (Q8HXX0) Platelet-activating factor acetylhydrolase IB alpha| subunit (PAF acetylhydrolase 45 kDa subunit) (PAF-AH 45 kDa subunit) (PAF-AH alpha) (PAFAH alpha) (Lissencephaly-1 protein) (LIS-1) Length = 409 Score = 43.5 bits (101), Expect = 3e-04 Identities = 26/85 (30%), Positives = 42/85 (49%) Frame = +1 Query: 235 WTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEV 414 W P +K Y LS GH S V +++ P +VS D + +W+ TG+ Sbjct: 93 WIPRPPEK--YALS----GHRSPVTRVIFHPVFS-----VMVSASEDATIKVWDYETGDF 141 Query: 415 AGTMKGHTSQVTGLAIDDNGDIISS 489 T+KGHT V ++ D +G +++S Sbjct: 142 ERTLKGHTDSVQDISFDHSGKLLTS 166 Score = 42.0 bits (97), Expect = 0.001 Identities = 31/116 (26%), Positives = 49/116 (42%), Gaps = 1/116 (0%) Frame = +1 Query: 145 LHGHEDDVRGICICGDVGVATS-SRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVW 321 L GH D V+ I + TS S D T++ W + + +T+ GH V + Sbjct: 145 LKGHTDSVQDISFDHSGKLLTSCSADMTIKLWDF-----QGFECIRTMHGHDHNVSSVAI 199 Query: 322 APPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISS 489 P D +VS D + +W + TG T GH V + + +G +I+S Sbjct: 200 MPNGDH-----LVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIAS 250 Score = 40.8 bits (94), Expect = 0.002 Identities = 30/115 (26%), Positives = 46/115 (40%), Gaps = 15/115 (13%) Frame = +1 Query: 199 VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRF------------ 342 +A+ S D+TVR W ++ + L H V + WAP S Sbjct: 248 IASCSNDQTVRVWVVATKECKA-----ELREHEHVVECISWAPESSYSSISEATGSETKK 302 Query: 343 ---PEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSSMD 498 P ++SG D + +W++ TG T+ GH + V G+ G I S D Sbjct: 303 SGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCAD 357 Score = 38.1 bits (87), Expect = 0.013 Identities = 33/120 (27%), Positives = 48/120 (40%), Gaps = 2/120 (1%) Frame = +1 Query: 145 LHGHEDDVRGICICGDVGVATS-SRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVW 321 L GH V + V S S D T++ W +TL GH+ V + + Sbjct: 103 LSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGD-----FERTLKGHTDSVQDISF 157 Query: 322 APPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGD-IISSSMD 498 + S D + LW+ E TM GH V+ +AI NGD ++S+S D Sbjct: 158 DHSGK-----LLTSCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHLVSASRD 212
>LIS1_HUMAN (P43034) Platelet-activating factor acetylhydrolase IB alpha| subunit (PAF acetylhydrolase 45 kDa subunit) (PAF-AH 45 kDa subunit) (PAF-AH alpha) (PAFAH alpha) (Lissencephaly-1 protein) (LIS-1) Length = 409 Score = 43.5 bits (101), Expect = 3e-04 Identities = 26/85 (30%), Positives = 42/85 (49%) Frame = +1 Query: 235 WTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEV 414 W P +K Y LS GH S V +++ P +VS D + +W+ TG+ Sbjct: 93 WIPRPPEK--YALS----GHRSPVTRVIFHPVFS-----VMVSASEDATIKVWDYETGDF 141 Query: 415 AGTMKGHTSQVTGLAIDDNGDIISS 489 T+KGHT V ++ D +G +++S Sbjct: 142 ERTLKGHTDSVQDISFDHSGKLLAS 166 Score = 42.0 bits (97), Expect = 0.001 Identities = 32/117 (27%), Positives = 51/117 (43%), Gaps = 2/117 (1%) Frame = +1 Query: 145 LHGHEDDVRGICI--CGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMV 318 L GH D V+ I G + +A+ S D T++ W + + +T+ GH V + Sbjct: 145 LKGHTDSVQDISFDHSGKL-LASCSADMTIKLWDF-----QGFECIRTMHGHDHNVSSVA 198 Query: 319 WAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISS 489 P D IVS D + +W + TG T GH V + + +G +I+S Sbjct: 199 IMPNGDH-----IVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIAS 250 Score = 40.8 bits (94), Expect = 0.002 Identities = 30/115 (26%), Positives = 46/115 (40%), Gaps = 15/115 (13%) Frame = +1 Query: 199 VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRF------------ 342 +A+ S D+TVR W ++ + L H V + WAP S Sbjct: 248 IASCSNDQTVRVWVVATKECKA-----ELREHEHVVECISWAPESSYSSISEATGSETKK 302 Query: 343 ---PEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSSMD 498 P ++SG D + +W++ TG T+ GH + V G+ G I S D Sbjct: 303 SGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCAD 357 Score = 38.9 bits (89), Expect = 0.008 Identities = 34/120 (28%), Positives = 48/120 (40%), Gaps = 2/120 (1%) Frame = +1 Query: 145 LHGHEDDVRGICICGDVGVATS-SRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVW 321 L GH V + V S S D T++ W +TL GH+ V + + Sbjct: 103 LSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGD-----FERTLKGHTDSVQDISF 157 Query: 322 APPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGD-IISSSMD 498 + S D + LW+ E TM GH V+ +AI NGD I+S+S D Sbjct: 158 DHSGK-----LLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRD 212
>LIS1_BOVIN (P43033) Platelet-activating factor acetylhydrolase IB alpha| subunit (PAF acetylhydrolase 45 kDa subunit) (PAF-AH 45 kDa subunit) (PAF-AH alpha) (PAFAH alpha) (Lissencephaly-1 protein) (LIS-1) Length = 409 Score = 43.5 bits (101), Expect = 3e-04 Identities = 26/85 (30%), Positives = 42/85 (49%) Frame = +1 Query: 235 WTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEV 414 W P +K Y LS GH S V +++ P +VS D + +W+ TG+ Sbjct: 93 WIPRPPEK--YALS----GHRSPVTRVIFHPVFS-----VMVSASEDATIKVWDYETGDF 141 Query: 415 AGTMKGHTSQVTGLAIDDNGDIISS 489 T+KGHT V ++ D +G +++S Sbjct: 142 ERTLKGHTDSVEDISFDHSGKLLAS 166 Score = 41.6 bits (96), Expect = 0.001 Identities = 32/117 (27%), Positives = 50/117 (42%), Gaps = 2/117 (1%) Frame = +1 Query: 145 LHGHEDDVRGICI--CGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMV 318 L GH D V I G + +A+ S D T++ W + + +T+ GH V + Sbjct: 145 LKGHTDSVEDISFDHSGKL-LASCSADMTIKLWDF-----QGFECIRTMHGHDHNVSSVA 198 Query: 319 WAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISS 489 P D IVS D + +W + TG T GH V + + +G +I+S Sbjct: 199 IMPNGDH-----IVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIAS 250 Score = 40.8 bits (94), Expect = 0.002 Identities = 30/115 (26%), Positives = 46/115 (40%), Gaps = 15/115 (13%) Frame = +1 Query: 199 VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRF------------ 342 +A+ S D+TVR W ++ + L H V + WAP S Sbjct: 248 IASCSNDQTVRVWVVATKECKA-----ELREHEHVVECISWAPESSYSSISEATGSETKK 302 Query: 343 ---PEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSSMD 498 P ++SG D + +W++ TG T+ GH + V G+ G I S D Sbjct: 303 SGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCAD 357 Score = 38.9 bits (89), Expect = 0.008 Identities = 34/120 (28%), Positives = 48/120 (40%), Gaps = 2/120 (1%) Frame = +1 Query: 145 LHGHEDDVRGICICGDVGVATS-SRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVW 321 L GH V + V S S D T++ W +TL GH+ V + + Sbjct: 103 LSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGD-----FERTLKGHTDSVEDISF 157 Query: 322 APPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGD-IISSSMD 498 + S D + LW+ E TM GH V+ +AI NGD I+S+S D Sbjct: 158 DHSGK-----LLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRD 212
>WSB2_MOUSE (O54929) WD repeat and SOCS box-containing protein 2 (WSB-2) (SOCS| box-containing WD protein SWiP-2) Length = 404 Score = 43.5 bits (101), Expect = 3e-04 Identities = 34/125 (27%), Positives = 58/125 (46%), Gaps = 3/125 (2%) Frame = +1 Query: 133 LSAQLHGHEDDVRGICIC--GDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFV 306 L L GH+D VR + G + + ++SRDKT+R W + K+ VLS GH +V Sbjct: 145 LLLNLSGHQDVVRDLSFTPSGSLILVSASRDKTLRIWDLNKHGKQIQVLS----GHLQWV 200 Query: 307 GPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAID-DNGDII 483 +P + S + V LW++ + + ++GH S V D+ ++ Sbjct: 201 YCCSISPDC-----SMLCSAAGEKSVFLWSMRSYTLIRKLEGHQSSVVSCDFSPDSALLV 255 Query: 484 SSSMD 498 ++S D Sbjct: 256 TASYD 260 Score = 29.6 bits (65), Expect = 4.7 Identities = 18/66 (27%), Positives = 33/66 (50%), Gaps = 5/66 (7%) Frame = +1 Query: 316 VWAPPSDRFPEGA---IVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDII- 483 +WA + P+ + + +G D Q+ +W + TG + + GH V L+ +G +I Sbjct: 110 LWARHHPQAPDVSCLILATGLNDGQIKIWEVQTGLLLLNLSGHQDVVRDLSFTPSGSLIL 169 Query: 484 -SSSMD 498 S+S D Sbjct: 170 VSASRD 175
>WSB2_HUMAN (Q9NYS7) WD repeat and SOCS box-containing protein 2 (WSB-2) (CS| box-containing WD protein) Length = 404 Score = 43.5 bits (101), Expect = 3e-04 Identities = 43/159 (27%), Positives = 65/159 (40%), Gaps = 40/159 (25%) Frame = +1 Query: 133 LSAQLHGHEDDVRGICIC--GDVGVATSSRDKTVRFWTQHPEKK---------------- 258 L L GH+D VR + G + + ++SRDKT+R W + K Sbjct: 145 LLLNLSGHQDVVRDLSFTPSGSLILVSASRDKTLRIWDLNKHGKQIQVLSGHLQWVYCCS 204 Query: 259 ----------------------REYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGM 372 R Y L + L GH S V ++P S +V+ Sbjct: 205 ISPDCSMLCSAAGEKSVFLWSMRSYTLIRKLEGHQSSVVSCDFSPDS-----ALLVTASY 259 Query: 373 DTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISS 489 DT V++W+ +TGE ++ H +QV A+DD+ ISS Sbjct: 260 DTNVIMWDPYTGERLRSL--HHTQVDP-AMDDSDVHISS 295 Score = 30.0 bits (66), Expect = 3.6 Identities = 18/66 (27%), Positives = 33/66 (50%), Gaps = 5/66 (7%) Frame = +1 Query: 316 VWAPPSDRFPEGA---IVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDII- 483 +WA + P+ + + +G D Q+ +W + TG + + GH V L+ +G +I Sbjct: 110 LWARHHPQVPDVSCLVLATGLNDGQIKIWEVQTGLLLLNLSGHQDVVRDLSFTPSGSLIL 169 Query: 484 -SSSMD 498 S+S D Sbjct: 170 VSASRD 175
>PRP19_RAT (Q9JMJ4) Pre-mRNA-splicing factor 19 (PRP19/PSO4 homolog) (Neuronal| differentiation-related gene protein) Length = 504 Score = 43.1 bits (100), Expect = 4e-04 Identities = 34/137 (24%), Positives = 59/137 (43%), Gaps = 5/137 (3%) Frame = +1 Query: 103 RPAPLMAAYHLSAQLHGHEDDVRGI-----CICGDVGVATSSRDKTVRFWTQHPEKKREY 267 +P L +++ + H + GI C + T DK V + +K E Sbjct: 200 KPEELSKYRQVASHVGLHSASIPGILALDLCPSDTNKILTGGADKNVVVF----DKSTEQ 255 Query: 268 VLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQV 447 +L+ TL GH+ V +V+ P + + S D + +W++ ++ H S V Sbjct: 256 ILA-TLKGHTKKVTSVVFHPSQE-----LVFSASPDATIRIWSVPNTSCVQVVRAHESAV 309 Query: 448 TGLAIDDNGDIISSSMD 498 TGL++ GD + SS D Sbjct: 310 TGLSLHATGDYLLSSSD 326 Score = 40.0 bits (92), Expect = 0.004 Identities = 26/93 (27%), Positives = 46/93 (49%) Frame = +1 Query: 214 RDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDTQVLLW 393 R KTV PE+ +Y + VG S P + A I++GG D V+++ Sbjct: 190 RGKTVPEELVKPEELSKYRQVASHVGLHSASIPGILALDLCPSDTNKILTGGADKNVVVF 249 Query: 394 NLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSS 492 + T ++ T+KGHT +VT + + +++ S+ Sbjct: 250 DKSTEQILATLKGHTKKVTSVVFHPSQELVFSA 282 Score = 37.4 bits (85), Expect = 0.023 Identities = 16/53 (30%), Positives = 30/53 (56%), Gaps = 1/53 (1%) Frame = +1 Query: 343 PEGAIV-SGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSSMD 498 P+G I +G MD+Q+ +W+L GH+ +T +A +NG ++++ D Sbjct: 360 PDGLIFGTGTMDSQIKIWDLKERTNVANFPGHSGPITSIAFSENGYYLATAAD 412
>PRP19_MOUSE (Q99KP6) Pre-mRNA-splicing factor 19 (PRP19/PSO4 homolog) (Nuclear| matrix protein 200) (Nuclear matrix protein SNEV) Length = 504 Score = 43.1 bits (100), Expect = 4e-04 Identities = 34/137 (24%), Positives = 59/137 (43%), Gaps = 5/137 (3%) Frame = +1 Query: 103 RPAPLMAAYHLSAQLHGHEDDVRGI-----CICGDVGVATSSRDKTVRFWTQHPEKKREY 267 +P L +++ + H + GI C + T DK V + +K E Sbjct: 200 KPEELSKYRQVASHVGLHSASIPGILALDLCPSDTNKILTGGADKNVVVF----DKSTEQ 255 Query: 268 VLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQV 447 +L+ TL GH+ V +V+ P + + S D + +W++ ++ H S V Sbjct: 256 ILA-TLKGHTKKVTSVVFHPSQE-----LVFSASPDATIRIWSVPNTSCVQVVRAHESAV 309 Query: 448 TGLAIDDNGDIISSSMD 498 TGL++ GD + SS D Sbjct: 310 TGLSLHATGDYLLSSSD 326 Score = 40.0 bits (92), Expect = 0.004 Identities = 26/93 (27%), Positives = 46/93 (49%) Frame = +1 Query: 214 RDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDTQVLLW 393 R KTV PE+ +Y + VG S P + A I++GG D V+++ Sbjct: 190 RGKTVPEELVKPEELSKYRQVASHVGLHSASIPGILALDLCPSDTNKILTGGADKNVVVF 249 Query: 394 NLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSS 492 + T ++ T+KGHT +VT + + +++ S+ Sbjct: 250 DKSTEQILATLKGHTKKVTSVVFHPSQELVFSA 282 Score = 37.4 bits (85), Expect = 0.023 Identities = 16/53 (30%), Positives = 30/53 (56%), Gaps = 1/53 (1%) Frame = +1 Query: 343 PEGAIV-SGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSSMD 498 P+G I +G MD+Q+ +W+L GH+ +T +A +NG ++++ D Sbjct: 360 PDGLIFGTGTMDSQIKIWDLKERTNVANFPGHSGPITSIAFSENGYYLATAAD 412
>HIRL_SCHPO (P87314) Histone transcription regulator 1 homolog| Length = 932 Score = 43.1 bits (100), Expect = 4e-04 Identities = 24/86 (27%), Positives = 42/86 (48%) Frame = +1 Query: 241 QHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAG 420 +H E R Y + L+GH + + + W+ S +VS G+D+ +++WN T E Sbjct: 119 KHTENWRSY---RRLLGHDNDIQDLCWSYDSQ-----LVVSVGLDSSIIVWNGTTFERLK 170 Query: 421 TMKGHTSQVTGLAIDDNGDIISSSMD 498 ++ H S V G+ D G ++ D Sbjct: 171 RIEAHQSHVKGITFDPAGKYFATESD 196
>WSB1_HUMAN (Q9Y6I7) WD repeat and SOCS box-containing protein 1 (WSB-1) (SOCS| box-containing WD protein SWiP-1) Length = 421 Score = 43.1 bits (100), Expect = 4e-04 Identities = 31/122 (25%), Positives = 56/122 (45%), Gaps = 2/122 (1%) Frame = +1 Query: 133 LSAQLHGHEDDVRGICIC--GDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFV 306 L L H + VR + G + + ++SRDKT+R W + K + + K L GH ++V Sbjct: 162 LLLNLVDHTEVVRDLTFAPDGSLILVSASRDKTLRVW----DLKDDGNMMKVLRGHQNWV 217 Query: 307 GPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIIS 486 ++P S + S G V LWN+ + ++GH V +G +++ Sbjct: 218 YSCAFSPDSSM-----LCSVGASKAVFLWNMDKYTMIRKLEGHHHDVVACDFSPDGALLA 272 Query: 487 SS 492 ++ Sbjct: 273 TA 274
>GBB3_HUMAN (P16520) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 3 (Transducin beta chain 3) Length = 340 Score = 43.1 bits (100), Expect = 4e-04 Identities = 29/122 (23%), Positives = 47/122 (38%) Frame = +1 Query: 133 LSAQLHGHEDDVRGICICGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGP 312 +S +L H + D + TSS D T W +++ VGH+ Sbjct: 135 VSRELSAHTGYLSCCRFLDDNNIVTSSGDTTCALWDIETGQQKT-----VFVGHTGDCMS 189 Query: 313 MVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSS 492 + +P + F +SG D LW++ G T GH S + + NG+ I + Sbjct: 190 LAVSPDFNLF-----ISGACDASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAICTG 244 Query: 493 MD 498 D Sbjct: 245 SD 246
>PRP46_ASPFU (Q4WT34) Pre-mRNA-splicing factor prp46 (Pre-mRNA-processing| protein 46) Length = 453 Score = 43.1 bits (100), Expect = 4e-04 Identities = 24/74 (32%), Positives = 37/74 (50%) Frame = +1 Query: 241 QHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAG 420 Q P+ + L + + GH +V + P ++ F SG D + +WNL TG + Sbjct: 126 QRPDWHPPWKLMRVISGHLGWVRSLAVEPNNEWF-----ASGAGDRTIKIWNLATGALRL 180 Query: 421 TMKGHTSQVTGLAI 462 T+ GH S V GLA+ Sbjct: 181 TLTGHISTVRGLAV 194 Score = 37.7 bits (86), Expect = 0.017 Identities = 34/120 (28%), Positives = 52/120 (43%), Gaps = 1/120 (0%) Frame = +1 Query: 127 YHLSAQLHGHEDDVRGICI-CGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSF 303 + L + GH VR + + + A+ + D+T++ W L TL GH S Sbjct: 134 WKLMRVISGHLGWVRSLAVEPNNEWFASGAGDRTIKIWNLATG-----ALRLTLTGHIST 188 Query: 304 VGPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDII 483 V + +P R P + S G D V W+L T +V GH S V LA+ D++ Sbjct: 189 VRGLAVSP---RHPY--LFSCGEDKMVKCWDLETNKVIRHYHGHLSGVYTLALHPRLDLL 243 Score = 36.6 bits (83), Expect = 0.039 Identities = 29/106 (27%), Positives = 43/106 (40%), Gaps = 1/106 (0%) Frame = +1 Query: 148 HGHEDDVRGICICGDVGV-ATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWA 324 HGH V + + + + T RD R W + +VLS GH V + Sbjct: 225 HGHLSGVYTLALHPRLDLLVTGGRDGVARVWDMRT-RSNIHVLS----GHKGTVADLKCQ 279 Query: 325 PPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAI 462 + I++G +D V LW+L G+ G + H V LAI Sbjct: 280 EADPQ-----IITGSLDATVRLWDLAAGKTMGVLTHHKKGVRNLAI 320
>GBB4_HUMAN (Q9HAV0) Guanine nucleotide-binding protein beta subunit 4| (Transducin beta chain 4) Length = 339 Score = 43.1 bits (100), Expect = 4e-04 Identities = 31/122 (25%), Positives = 48/122 (39%) Frame = +1 Query: 133 LSAQLHGHEDDVRGICICGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGP 312 +S +L GH + D + TSS D T W ++ + T GHS V Sbjct: 134 VSRELPGHTGYLSCCRFLDDSQIVTSSGDTTCALWDIETAQQ-----TTTFTGHSGDVMS 188 Query: 313 MVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSS 492 + +P F VSG D LW++ G + GH S + ++ NG ++ Sbjct: 189 LSLSPDMRTF-----VSGACDASSKLWDIRDGMCRQSFTGHVSDINAVSFFPNGYAFATG 243 Query: 493 MD 498 D Sbjct: 244 SD 245 Score = 30.0 bits (66), Expect = 3.6 Identities = 25/116 (21%), Positives = 51/116 (43%), Gaps = 3/116 (2%) Frame = +1 Query: 151 GHEDDVRGICICGD-VGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAP 327 GH D+ + + AT S D T R + +++ L H + + + Sbjct: 223 GHVSDINAVSFFPNGYAFATGSDDATCRLFDLRADQEL------LLYSHDNIICGIT--- 273 Query: 328 PSDRFPEGA--IVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISS 489 S F + +++G D +W+ G+ AG + GH ++V+ L + D+G +++ Sbjct: 274 -SVAFSKSGRLLLAGYDDFNCNVWDTLKGDRAGVLAGHDNRVSCLGVTDDGMAVAT 328
>APAF_RAT (Q9EPV5) Apoptotic protease-activating factor 1 (Apaf-1)| Length = 1249 Score = 43.1 bits (100), Expect = 4e-04 Identities = 33/116 (28%), Positives = 51/116 (43%), Gaps = 1/116 (0%) Frame = +1 Query: 145 LHGHEDDVRGICICGDVG-VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVW 321 + HED+V D +AT S DK V+ W K L T HS V + Sbjct: 653 IKAHEDEVLCCAFSSDDSYIATCSVDKKVKIWDSGTGK-----LVHTYEEHSEQVNCCHF 707 Query: 322 APPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISS 489 S+ + +G D+ + LW+L+ E TM GHT+ VT + ++++S Sbjct: 708 TNKSNHL---LLATGSNDSFLKLWDLNQKECRNTMFGHTNSVTHCRFSPDDELLAS 760
>WDR1_HUMAN (O75083) WD-repeat protein 1 (Actin-interacting protein 1) (AIP1)| (NORI-1) Length = 605 Score = 42.7 bits (99), Expect = 5e-04 Identities = 23/51 (45%), Positives = 32/51 (62%), Gaps = 3/51 (5%) Frame = +1 Query: 355 IVSGGMDTQVLLWNLHTGE---VAGTMKGHTSQVTGLAIDDNGDIISSSMD 498 I SG D + W+ TGE AG KGHT+QV+ + +D++G +IS SMD Sbjct: 336 IYSGSHDGHINYWDSETGENDSFAG--KGHTNQVSRMTVDESGQLISCSMD 384 Score = 33.1 bits (74), Expect = 0.43 Identities = 21/80 (26%), Positives = 36/80 (45%), Gaps = 2/80 (2%) Frame = +1 Query: 265 YVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKG--HT 438 Y + GH + + + W+P ++ F SGGMD V +W L E ++ Sbjct: 521 YSENNVFYGHHAKIVCLAWSPDNEHF-----ASGGMDMMVYVWTLSDPETRVKIQDAHRL 575 Query: 439 SQVTGLAIDDNGDIISSSMD 498 V+ LA D ++++S D Sbjct: 576 HHVSSLAWLDEHTLVTTSHD 595
>LIN23_CAEEL (Q09990) F-box/WD-repeat protein lin-23 (Abnormal cell lineage| protein 23) Length = 665 Score = 42.7 bits (99), Expect = 5e-04 Identities = 28/103 (27%), Positives = 48/103 (46%) Frame = +1 Query: 190 DVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGG 369 D + + RD T++ W +++Y S+ L GH+ V + ++ I+SG Sbjct: 232 DDKIVSGLRDNTIKIWD-----RKDYSCSRILSGHTGSVLCL-------QYDNRVIISGS 279 Query: 370 MDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSSMD 498 D V +W++ TGE T+ H V L NG +++ S D Sbjct: 280 SDATVRVWDVETGECIKTLIHHCEAVLHLRF-ANGIMVTCSKD 321 Score = 40.4 bits (93), Expect = 0.003 Identities = 25/100 (25%), Positives = 49/100 (49%) Frame = +1 Query: 199 VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDT 378 + ++S D+T++ W+ E+V +TL GH + + ++ +VSG D Sbjct: 358 IVSASGDRTIKVWSMDT---LEFV--RTLAGHRRGIACL-------QYRGRLVVSGSSDN 405 Query: 379 QVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSSMD 498 + LW++H+G ++GH V + D+ I+S + D Sbjct: 406 TIRLWDIHSGVCLRVLEGHEELVRCIRFDEK-RIVSGAYD 444 Score = 38.1 bits (87), Expect = 0.013 Identities = 34/109 (31%), Positives = 48/109 (44%), Gaps = 9/109 (8%) Frame = +1 Query: 199 VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDT 378 V + S D T+R W H V + L GH V + RF E IVSG D Sbjct: 398 VVSGSSDNTIRLWDIHSG-----VCLRVLEGHEELVRCI-------RFDEKRIVSGAYDG 445 Query: 379 QVLLWNLH--------TGEVA-GTMKGHTSQVTGLAIDDNGDIISSSMD 498 ++ +W+L + E+ ++ HT +V L DD I+SSS D Sbjct: 446 KIKVWDLQAALDPRALSSEICLCSLVQHTGRVFRLQFDD-FQIVSSSHD 493 Score = 35.8 bits (81), Expect = 0.066 Identities = 22/79 (27%), Positives = 39/79 (49%) Frame = +1 Query: 199 VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDT 378 + T S+D+++ W R+ + + LVGH + V + + DR+ IVS D Sbjct: 315 MVTCSKDRSIAVWDM--VSPRDITIRRVLVGHRAAVNVVDF---DDRY----IVSASGDR 365 Query: 379 QVLLWNLHTGEVAGTMKGH 435 + +W++ T E T+ GH Sbjct: 366 TIKVWSMDTLEFVRTLAGH 384 Score = 29.6 bits (65), Expect = 4.7 Identities = 18/54 (33%), Positives = 26/54 (48%) Frame = +1 Query: 337 RFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSSMD 498 ++ + IVSG D + +W+ + + GHT V L DN IIS S D Sbjct: 229 QYDDDKIVSGLRDNTIKIWDRKDYSCSRILSGHTGSVLCLQY-DNRVIISGSSD 281
>EBI_DROME (Q95RJ9) F-box-like/WD repeat protein ebi| Length = 700 Score = 42.7 bits (99), Expect = 5e-04 Identities = 31/119 (26%), Positives = 55/119 (46%), Gaps = 6/119 (5%) Frame = +1 Query: 151 GHEDDVRGICIC--GDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWA 324 GH ++V I C G + +A+ S D T++ W+ + ++ L HS + + W+ Sbjct: 532 GHTNEVNAIKWCPQGQL-LASCSDDMTLKIWSMNRDR-----CCHDLQAHSKEIYTIKWS 585 Query: 325 P--PSDRFPEGAIV--SGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISS 489 P P P ++ S D+ V LW++ G T+ HT V +A +G ++S Sbjct: 586 PTGPGTNNPNTNLILASASFDSTVRLWDVERGSCIHTLTKHTEPVYSVAFSPDGKHLAS 644 Score = 31.2 bits (69), Expect = 1.6 Identities = 22/78 (28%), Positives = 38/78 (48%) Frame = +1 Query: 199 VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDT 378 +A++S D TVR W + +R + TL H+ V + ++P + SG D Sbjct: 600 LASASFDSTVRLW----DVERGSCIH-TLTKHTEPVYSVAFSPDGKH-----LASGSFDK 649 Query: 379 QVLLWNLHTGEVAGTMKG 432 V +W+ TG++ + KG Sbjct: 650 CVHIWSTQTGQLVHSYKG 667 Score = 30.8 bits (68), Expect = 2.1 Identities = 25/105 (23%), Positives = 40/105 (38%) Frame = +1 Query: 184 CGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVS 363 C +AT S D R W K + L+ TL H + + W + I+S Sbjct: 420 CDGSLLATGSYDGYARIW------KTDGRLASTLGQHKGPIFALKWNKCGNY-----ILS 468 Query: 364 GGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSSMD 498 G+D ++W+ TG+ H++ + N S S D Sbjct: 469 AGVDKTTIIWDASTGQCTQQFAFHSAPALDVDWQTNQAFASCSTD 513
>LIS1_DROME (Q7KNS3) Lissencephaly-1 homolog (Lissencephaly1) (Dlis1) (DLis-1)| Length = 411 Score = 42.7 bits (99), Expect = 5e-04 Identities = 28/116 (24%), Positives = 50/116 (43%), Gaps = 1/116 (0%) Frame = +1 Query: 145 LHGHEDDVRGICICGDVGV-ATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVW 321 L GH D V+ + + A+ S D +++ W + ++ Y KT+ GH V + + Sbjct: 146 LKGHTDSVQDVAFDAQGKLLASCSADLSIKLW----DFQQSYECIKTMHGHDHNVSSVAF 201 Query: 322 APPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISS 489 P D ++S D + +W + TG T GH V + + G I ++ Sbjct: 202 VPAGDY-----VLSASRDRTIKMWEVATGYCVKTYTGHREWVRMVRVHIEGSIFAT 252 Score = 42.7 bits (99), Expect = 5e-04 Identities = 25/96 (26%), Positives = 44/96 (45%) Frame = +1 Query: 202 ATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDTQ 381 A + +T W P +K +L GH + + +++ P +VS D Sbjct: 83 APTKNKRTPGEWIPRPPEKF------SLTGHRASITRVIFHPIF-----ALMVSASEDAT 131 Query: 382 VLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISS 489 + +W+ TGE ++KGHT V +A D G +++S Sbjct: 132 IRIWDFETGEYERSLKGHTDSVQDVAFDAQGKLLAS 167 Score = 42.0 bits (97), Expect = 0.001 Identities = 37/133 (27%), Positives = 56/133 (42%), Gaps = 17/133 (12%) Frame = +1 Query: 151 GHEDDVRGICICGDVGV-ATSSRDKTVRFW-TQHPEKKREYVLSKTLVGHSSFVGPMVWA 324 GH + VR + + + + AT S D+T+R W T + K E L H V + WA Sbjct: 233 GHREWVRMVRVHIEGSIFATCSNDQTIRVWLTNSKDCKVE------LRDHEHTVECIAWA 286 Query: 325 PPS--DRFPEGA-------------IVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLA 459 P + E A + SG D + +W++ G T+ GH + V GLA Sbjct: 287 PEAAASAINEAAGADNKKGHHQGPFLASGSRDKTIRIWDVSVGLCLLTLSGHDNWVRGLA 346 Query: 460 IDDNGDIISSSMD 498 G + S+ D Sbjct: 347 FHPGGKYLVSASD 359
>SPG16_MOUSE (Q8K450) Sperm-associated antigen 16 protein (PF20 protein homolog)| Length = 639 Score = 42.7 bits (99), Expect = 5e-04 Identities = 29/102 (28%), Positives = 48/102 (47%) Frame = +1 Query: 184 CGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVS 363 CGD VA++S D T + W + E+ R TL GH+ V + + P S+ +++ Sbjct: 455 CGDF-VASASLDMTSKIWDVNSERCRY-----TLYGHTDSVNSIEFFPFSN-----ILLT 503 Query: 364 GGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISS 489 D + +W+ TG+ ++ GH V G II+S Sbjct: 504 ASADKTLSVWDARTGKCEQSLYGHMHSVNDATFTPRGHIIAS 545 Score = 40.8 bits (94), Expect = 0.002 Identities = 30/103 (29%), Positives = 45/103 (43%), Gaps = 1/103 (0%) Frame = +1 Query: 151 GHEDDVRGICICGDVG-VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAP 327 GH D + G C +ATSS D T++ W + K E L TL GH+ V W Sbjct: 400 GHTDWLSGCCFHPSGSKLATSSGDSTIKLWDLN---KGECTL--TLEGHNHAVWSCTWHS 454 Query: 328 PSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGL 456 D + S +D +W++++ T+ GHT V + Sbjct: 455 CGD-----FVASASLDMTSKIWDVNSERCRYTLYGHTDSVNSI 492 Score = 32.3 bits (72), Expect = 0.73 Identities = 19/68 (27%), Positives = 33/68 (48%) Frame = +1 Query: 289 GHSSFVGPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDD 468 GH+ ++ + P + A SG D+ + LW+L+ GE T++GH V Sbjct: 400 GHTDWLSGCCFHPSGSKL---ATSSG--DSTIKLWDLNKGECTLTLEGHNHAVWSCTWHS 454 Query: 469 NGDIISSS 492 GD ++S+ Sbjct: 455 CGDFVASA 462
>FBW1B_HUMAN (Q9UKB1) F-box/WD-repeat protein 11 (F-box/WD-repeat protein 1B)| (F-box and WD-repeats protein beta-TrCP2) Length = 542 Score = 42.7 bits (99), Expect = 5e-04 Identities = 29/103 (28%), Positives = 48/103 (46%) Frame = +1 Query: 190 DVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGG 369 D + + RD +++ W K K L GH+ V + ++ E IV+G Sbjct: 250 DEKIISGLRDNSIKIWD-----KTSLECLKVLTGHTGSVLCL-------QYDERVIVTGS 297 Query: 370 MDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSSMD 498 D+ V +W+++TGEV T+ H V L NG +++ S D Sbjct: 298 SDSTVRVWDVNTGEVLNTLIHHNEAVLHLRF-SNGLMVTCSKD 339 Score = 38.5 bits (88), Expect = 0.010 Identities = 26/103 (25%), Positives = 49/103 (47%) Frame = +1 Query: 190 DVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGG 369 D + ++S D+T++ W+ E+V +TL GH + + ++ + +VSG Sbjct: 373 DKYIVSASGDRTIKVWST---STCEFV--RTLNGHKRGIACL-------QYRDRLVVSGS 420 Query: 370 MDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSSMD 498 D + LW++ G ++GH V + DN I+S + D Sbjct: 421 SDNTIRLWDIECGACLRVLEGHEELVRCIRF-DNKRIVSGAYD 462 Score = 36.2 bits (82), Expect = 0.051 Identities = 26/100 (26%), Positives = 43/100 (43%) Frame = +1 Query: 199 VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDT 378 + T S+D+++ W + L + LVGH + V + F + IVS D Sbjct: 333 MVTCSKDRSIAVWDM--ASATDITLRRVLVGHRAAVNVV-------DFDDKYIVSASGDR 383 Query: 379 QVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSSMD 498 + +W+ T E T+ GH + L D ++S S D Sbjct: 384 TIKVWSTSTCEFVRTLNGHKRGIACLQYRDR-LVVSGSSD 422 Score = 30.0 bits (66), Expect = 3.6 Identities = 37/129 (28%), Positives = 51/129 (39%), Gaps = 11/129 (8%) Frame = +1 Query: 145 LHGHEDDVRGICICG--DVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMV 318 L+GH+ RGI D V + S D T+R W + L GH V + Sbjct: 399 LNGHK---RGIACLQYRDRLVVSGSSDNTIRLWDIECG-----ACLRVLEGHEELVRCI- 449 Query: 319 WAPPSDRFPEGAIVSGGMDTQVLLWNLHTG---------EVAGTMKGHTSQVTGLAIDDN 471 RF IVSG D ++ +W+L T+ H+ +V L D+ Sbjct: 450 ------RFDNKRIVSGAYDGKIKVWDLQAALDPRAPASTLCLRTLVEHSGRVFRLQFDE- 502 Query: 472 GDIISSSMD 498 IISSS D Sbjct: 503 FQIISSSHD 511 Score = 28.9 bits (63), Expect = 8.1 Identities = 14/52 (26%), Positives = 25/52 (48%) Frame = +1 Query: 337 RFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSS 492 ++ + I+SG D + +W+ + E + GHT V L D+ + SS Sbjct: 247 QYDDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSVLCLQYDERVIVTGSS 298
>GBB3_RAT (P52287) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 3 (Transducin beta chain 3) Length = 340 Score = 42.4 bits (98), Expect = 7e-04 Identities = 29/122 (23%), Positives = 46/122 (37%) Frame = +1 Query: 133 LSAQLHGHEDDVRGICICGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGP 312 +S +L H + D + TSS D T W +++ VGH+ Sbjct: 135 VSRELSAHTGYLSCCRFLDDNNIVTSSGDTTCALWDIETGQQKT-----VFVGHTGDCMS 189 Query: 313 MVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSS 492 + +P F +SG D LW++ G T GH S + + NG+ I + Sbjct: 190 LAVSPDYKLF-----ISGACDASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAICTG 244 Query: 493 MD 498 D Sbjct: 245 SD 246
>GBB3_MOUSE (Q61011) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 3 (Transducin beta chain 3) Length = 340 Score = 42.4 bits (98), Expect = 7e-04 Identities = 29/122 (23%), Positives = 46/122 (37%) Frame = +1 Query: 133 LSAQLHGHEDDVRGICICGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGP 312 +S +L H + D + TSS D T W +++ VGH+ Sbjct: 135 VSRELSAHTGYLSCCRFLDDNNIVTSSGDTTCALWDIETGQQKT-----VFVGHTGDCMS 189 Query: 313 MVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSS 492 + +P F +SG D LW++ G T GH S + + NG+ I + Sbjct: 190 LAVSPDYKLF-----ISGACDASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAICTG 244 Query: 493 MD 498 D Sbjct: 245 SD 246
>GBB3_CANFA (P79147) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 3 (Transducin beta chain 3) Length = 340 Score = 42.4 bits (98), Expect = 7e-04 Identities = 29/122 (23%), Positives = 46/122 (37%) Frame = +1 Query: 133 LSAQLHGHEDDVRGICICGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGP 312 +S +L H + D + TSS D T W +++ VGH+ Sbjct: 135 VSRELSAHTGYLSCCRFLDDNNIVTSSGDTTCALWDIETGQQKT-----VFVGHTGDCMS 189 Query: 313 MVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSS 492 + +P F +SG D LW++ G T GH S + + NG+ I + Sbjct: 190 LAVSPDFKLF-----ISGACDASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAICTG 244 Query: 493 MD 498 D Sbjct: 245 SD 246 Score = 31.2 bits (69), Expect = 1.6 Identities = 23/115 (20%), Positives = 50/115 (43%), Gaps = 2/115 (1%) Frame = +1 Query: 151 GHEDDVRGICICGD-VGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAP 327 GHE D+ IC + + T S D + R + +++ ++++ + V + Sbjct: 224 GHESDINAICFFPNGEAICTGSDDASCRLFDLRADQELTAYSDESIICGITSVAFSL--- 280 Query: 328 PSDRFPEGAIVSGGMDT-QVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISS 489 G ++ G D +W+ GE G + GH ++V+ L + +G +++ Sbjct: 281 ------SGRLLFAGYDDFNCNIWDSMKGERVGILSGHDNRVSCLGVTADGMAVAT 329
>YGA4_YEAST (P53196) Hypothetical 46.4 kDa Trp-Asp repeats-containing protein| in PMC1-TFG2 intergenic region Length = 417 Score = 42.0 bits (97), Expect = 0.001 Identities = 21/55 (38%), Positives = 35/55 (63%), Gaps = 2/55 (3%) Frame = +1 Query: 340 FPEG-AIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNG-DIISSSMD 498 FP G A++S D Q+ +W++ G T+ GH + VT +AI D G +++S+S+D Sbjct: 145 FPSGEALISSSQDMQLKIWSVKDGSNPRTLIGHRATVTDIAIIDRGRNVLSASLD 199
>RCO1_NEUCR (P78706) Transcriptional repressor rco-1| Length = 604 Score = 42.0 bits (97), Expect = 0.001 Identities = 31/113 (27%), Positives = 47/113 (41%), Gaps = 10/113 (8%) Frame = +1 Query: 151 GHEDDVRGICICGDV-GVATSSRDKTVRFW---------TQHPEKKREYVLSKTLVGHSS 300 GH+D V + D + + S DKT++ W + P K + KT GH Sbjct: 469 GHKDSVYSVAFSPDGRNLVSGSLDKTIKMWELSAPRGIPSSAPPKGGRCI--KTFEGHRD 526 Query: 301 FVGPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLA 459 FV + P S ++SG D V W+ TG ++GH + V +A Sbjct: 527 FVLSVALTPDSQW-----VLSGSKDRGVQFWDPRTGHTQLMLQGHKNSVISVA 574 Score = 33.1 bits (74), Expect = 0.43 Identities = 35/130 (26%), Positives = 52/130 (40%), Gaps = 16/130 (12%) Frame = +1 Query: 157 EDDVRGICICGDVG-VATSSRDKTVRFWTQHPEKKREYVLSKT--LVGHSSFVGPMVWAP 327 ED V + I D VA S DK+VR W R Y+ + GH V + ++P Sbjct: 427 EDGVTTVAISPDKQFVAAGSLDKSVRVWDM-----RGYLAERLEGPDGHKDSVYSVAFSP 481 Query: 328 PSDRFPEGAIVSGGMDTQVLLWNLHT------------GEVAGTMKGHTSQVTGLAI-DD 468 +VSG +D + +W L G T +GH V +A+ D Sbjct: 482 DGRN-----LVSGSLDKTIKMWELSAPRGIPSSAPPKGGRCIKTFEGHRDFVLSVALTPD 536 Query: 469 NGDIISSSMD 498 + ++S S D Sbjct: 537 SQWVLSGSKD 546 Score = 31.6 bits (70), Expect = 1.2 Identities = 26/112 (23%), Positives = 42/112 (37%), Gaps = 1/112 (0%) Frame = +1 Query: 166 VRGICICGDVG-VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRF 342 +R +C D +AT + DK +R W R T GH + + ++ Sbjct: 347 IRSVCFSPDGKYLATGAEDKLIRVWDIQSRTIRN-----TFHGHEQDIYSLDFSRDGR-- 399 Query: 343 PEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSSMD 498 I SG D V LW++ TG+ + T D + + S+D Sbjct: 400 ---TIASGSGDRTVRLWDIETGQNTSVLSIEDGVTTVAISPDKQFVAAGSLD 448
>COR1A_MOUSE (O89053) Coronin-1A (Coronin-like protein p57) (Coronin-like| protein A) (CLIPINA) (Tryptophan aspartate-containing coat protein) (TACO) Length = 461 Score = 42.0 bits (97), Expect = 0.001 Identities = 35/116 (30%), Positives = 54/116 (46%), Gaps = 7/116 (6%) Frame = +1 Query: 151 GHEDDVRGICIC--GDVGVATSSRDKTVRFWTQHPE-----KKREYVLSKTLVGHSSFVG 309 GH V I C D +A+ S D TV W + P+ RE V+ TL GH+ VG Sbjct: 79 GHTAPVLDIAWCPHNDNVIASGSEDCTVMVW-EIPDGGLVLPLREPVI--TLEGHTKRVG 135 Query: 310 PMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGD 477 + W P + + ++S G D +L+W++ TG T+ T ++D + D Sbjct: 136 IVAWHPTA----QNVLLSAGCDNVILVWDVGTGAAVLTLGPDVHPDTIYSVDWSRD 187
>PRP46_YEAST (Q12417) Pre-mRNA-splicing factor PRP46 (Pre-mRNA-processing| protein 46) (Complexed with CEF1 protein 1) (PRP19-associated complex protein 50) (PRP nineteen-associated complex protein 50) Length = 451 Score = 42.0 bits (97), Expect = 0.001 Identities = 22/77 (28%), Positives = 40/77 (51%) Frame = +1 Query: 238 TQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVA 417 +Q PE + LS+ + GH +V + P + + ++G DT + +W+L TG++ Sbjct: 120 SQRPEWHAPWKLSRVINGHLGWVRCVAIDPVDNEW----FITGSNDTTMKVWDLATGKLK 175 Query: 418 GTMKGHTSQVTGLAIDD 468 T+ GH V +A+ D Sbjct: 176 TTLAGHVMTVRDVAVSD 192 Score = 37.7 bits (86), Expect = 0.017 Identities = 36/126 (28%), Positives = 54/126 (42%), Gaps = 2/126 (1%) Frame = +1 Query: 121 AAYHLSAQLHGHEDDVRGICI--CGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGH 294 A + LS ++GH VR + I + T S D T++ W K L TL GH Sbjct: 127 APWKLSRVINGHLGWVRCVAIDPVDNEWFITGSNDTTMKVWDLATGK-----LKTTLAGH 181 Query: 295 SSFVGPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNG 474 V + SDR P + S D V W+L ++ GH S V ++I Sbjct: 182 VMTVRDVA---VSDRHPY--LFSVSEDKTVKCWDLEKNQIIRDYYGHLSGVRTVSIHPTL 236 Query: 475 DIISSS 492 D+I+++ Sbjct: 237 DLIATA 242 Score = 34.7 bits (78), Expect = 0.15 Identities = 36/131 (27%), Positives = 54/131 (41%), Gaps = 4/131 (3%) Frame = +1 Query: 118 MAAYHLSAQLHGHEDDVRGICICGDVGVATS-SRDKTVRFWTQHPEKKREYVLSKTLVGH 294 +A L L GH VR + + S S DKTV+ W + + + GH Sbjct: 169 LATGKLKTTLAGHVMTVRDVAVSDRHPYLFSVSEDKTVKCWDLEKNQ-----IIRDYYGH 223 Query: 295 SSFVGPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGH---TSQVTGLAID 465 S V + P D I + G D+ + LW++ T T+ GH +QV +D Sbjct: 224 LSGVRTVSIHPTLD-----LIATAGRDSVIKLWDMRTRIPVITLVGHKGPINQVQCTPVD 278 Query: 466 DNGDIISSSMD 498 ++SSS D Sbjct: 279 P--QVVSSSTD 287
>LEUNG_ARATH (Q9FUY2) Transcriptional corepressor LEUNIG| Length = 931 Score = 42.0 bits (97), Expect = 0.001 Identities = 28/83 (33%), Positives = 42/83 (50%) Frame = +1 Query: 199 VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDT 378 +ATSS DKTVR W + Y L +T +GHSS V + + P D I S D Sbjct: 708 LATSSFDKTVRVW---DADNKGYSL-RTFMGHSSMVTSLDFHPIKD----DLICSCDNDN 759 Query: 379 QVLLWNLHTGEVAGTMKGHTSQV 447 ++ W+++ G KG ++Q+ Sbjct: 760 EIRYWSINNGSCTRVYKGGSTQI 782
>YJL2_YEAST (P47025) Hypothetical 80.0 kDa Trp-Asp repeats-containing protein| in ASF1-CCT7 intergenic region Length = 714 Score = 42.0 bits (97), Expect = 0.001 Identities = 34/130 (26%), Positives = 59/130 (45%), Gaps = 15/130 (11%) Frame = +1 Query: 154 HEDDVRGICICGDVGVATSSRDKTVRFWTQHPEKKREYV---------------LSKTLV 288 H D+V + + + + S+D+T+R W K + + LSK+ + Sbjct: 501 HTDEVTALSLDPSF-LVSGSQDRTIRQWDLRSGKCLQTIDLSFANVLTTSTNVDLSKSTL 559 Query: 289 GHSSFVGPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDD 468 P + A S + A+ +G D V LW+L +G+V T+KGHT +T L D Sbjct: 560 LTQRNERPSIGALQSF---DAALATGTKDGVVRLWDLRSGKVIRTLKGHTDAITSLKF-D 615 Query: 469 NGDIISSSMD 498 + +++ S D Sbjct: 616 SACLVTGSYD 625 Score = 32.3 bits (72), Expect = 0.73 Identities = 28/113 (24%), Positives = 44/113 (38%), Gaps = 19/113 (16%) Frame = +1 Query: 217 DKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDTQVLLWN 396 D TV+ W + K L GH + + M G +V+GG D + LWN Sbjct: 420 DHTVKIWDLSKQNK-----IGELAGHLATINCM-----QINRDYGTLVTGGRDAALKLWN 469 Query: 397 LHTGE-------------------VAGTMKGHTSQVTGLAIDDNGDIISSSMD 498 L+ + T + HT +VT L++D + ++S S D Sbjct: 470 LNLAQQLYQETQNLTSPTNHIDSPCVHTFEAHTDEVTALSLDPS-FLVSGSQD 521
>TUP1_KLULA (P56094) Transcriptional repressor TUP1| Length = 682 Score = 42.0 bits (97), Expect = 0.001 Identities = 30/107 (28%), Positives = 47/107 (43%), Gaps = 3/107 (2%) Frame = +1 Query: 151 GHEDDVRGICICGD-VGVATSSRDKTVRFWTQH--PEKKREYVLSKTLVGHSSFVGPMVW 321 GH D V + D GV + S D++V+ W + +K T GH FV V Sbjct: 537 GHRDSVYSVVFTRDGKGVVSGSLDRSVKLWNLNGLSGQKSHAECEVTYTGHKDFV-LSVA 595 Query: 322 APPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAI 462 +D + I+SG D VL W+ +G ++GH + V + + Sbjct: 596 TTQNDEY----ILSGSKDRGVLFWDTKSGNPLLMLQGHRNSVISVTV 638 Score = 40.0 bits (92), Expect = 0.004 Identities = 31/110 (28%), Positives = 47/110 (42%), Gaps = 2/110 (1%) Frame = +1 Query: 166 VRGICICGDVG-VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRF 342 +R +C D +AT + DK +R W +K + TL GH + + D F Sbjct: 409 IRSVCFSPDGKFLATGAEDKLIRIWDLETKK-----IVMTLKGHEQDIYSL------DYF 457 Query: 343 PEG-AIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISS 489 P G +VSG D V +W+L TG + T+ T G I++ Sbjct: 458 PSGNKLVSGSGDRTVRIWDLTTGTCSLTLSIEDGVTTVAVSPGEGKFIAA 507 Score = 37.0 bits (84), Expect = 0.030 Identities = 37/126 (29%), Positives = 52/126 (41%), Gaps = 12/126 (9%) Frame = +1 Query: 157 EDDVRGICICGDVG--VATSSRDKTVRFWTQHPEKKREYVLSKTLV--GHSSFVGPMVWA 324 ED V + + G +A S D+TVR W E + S+ + GH V +V+ Sbjct: 489 EDGVTTVAVSPGEGKFIAAGSLDRTVRVWDSDTGFLVERLDSENELGTGHRDSVYSVVFT 548 Query: 325 PPSDRFPEGAIVSGGMDTQVLLWNLH-------TGEVAGTMKGHTSQVTGLAIDDNGD-I 480 +VSG +D V LWNL+ E T GH V +A N + I Sbjct: 549 RDGK-----GVVSGSLDRSVKLWNLNGLSGQKSHAECEVTYTGHKDFVLSVATTQNDEYI 603 Query: 481 ISSSMD 498 +S S D Sbjct: 604 LSGSKD 609 Score = 31.6 bits (70), Expect = 1.2 Identities = 16/54 (29%), Positives = 30/54 (55%), Gaps = 2/54 (3%) Frame = +1 Query: 343 PEGA-IVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGD-IISSSMD 498 P+G + +G D + +W+L T ++ T+KGH + L +G+ ++S S D Sbjct: 416 PDGKFLATGAEDKLIRIWDLETKKIVMTLKGHEQDIYSLDYFPSGNKLVSGSGD 469
>MET30_YEAST (P39014) F-box protein MET30 (Methionine requiring protein 30) (E3| ubiquitin ligase complex SCF(Met30) subunit MET30) Length = 640 Score = 42.0 bits (97), Expect = 0.001 Identities = 28/95 (29%), Positives = 43/95 (45%) Frame = +1 Query: 205 TSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDTQV 384 T S D T+ W K L + L GHS V + F + +++G +D + Sbjct: 317 TGSYDSTIGIWDLFTGK-----LIRRLSGHSDGVKTLY-------FDDRKLITGSLDKTI 364 Query: 385 LLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISS 489 +WN TGE T +GH+ V L++D +I S Sbjct: 365 RVWNYITGECISTYRGHSDSV--LSVDSYQKVIVS 397 Score = 40.0 bits (92), Expect = 0.004 Identities = 30/99 (30%), Positives = 44/99 (44%) Frame = +1 Query: 151 GHEDDVRGICICGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPP 330 GH D V + V + + S DKTV+ W H E + Y TL GH+ +V + P Sbjct: 380 GHSDSVLSVDSYQKV-IVSGSADKTVKVW--HVESRTCY----TLRGHTEWVNCVKLHPK 432 Query: 331 SDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQV 447 S + S DT + +W++ T +GH QV Sbjct: 433 SF-----SCFSCSDDTTIRMWDIRTNSCLKVFRGHVGQV 466 Score = 36.6 bits (83), Expect = 0.039 Identities = 33/108 (30%), Positives = 49/108 (45%), Gaps = 3/108 (2%) Frame = +1 Query: 133 LSAQLHGHEDDVRGICICGDVGVATSSRDKTVRFWTQHPEKKREYVLSK---TLVGHSSF 303 L +L GH D V+ + D + T S DKT+R W Y+ + T GHS Sbjct: 334 LIRRLSGHSDGVKTLYF-DDRKLITGSLDKTIRVW--------NYITGECISTYRGHSDS 384 Query: 304 VGPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQV 447 V + D + + IVSG D V +W++ + T++GHT V Sbjct: 385 VLSV------DSY-QKVIVSGSADKTVKVWHVES-RTCYTLRGHTEWV 424 Score = 34.3 bits (77), Expect = 0.19 Identities = 19/48 (39%), Positives = 27/48 (56%) Frame = +1 Query: 355 IVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSSMD 498 ++S G+D + LW++ TG+ T GH V +A DN IIS S D Sbjct: 525 LLSCGLDNTIKLWDVKTGKCIRTQFGHVEGVWDIAA-DNFRIISGSHD 571 Score = 33.1 bits (74), Expect = 0.43 Identities = 15/48 (31%), Positives = 28/48 (58%) Frame = +1 Query: 355 IVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSSMD 498 + +G D+ + +W+L TG++ + GH+ V L DD +I+ S+D Sbjct: 315 LFTGSYDSTIGIWDLFTGKLIRRLSGHSDGVKTLYFDDR-KLITGSLD 361 Score = 29.6 bits (65), Expect = 4.7 Identities = 21/76 (27%), Positives = 31/76 (40%) Frame = +1 Query: 217 DKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDTQVLLWN 396 D T++ W K +T GH V W +D F I+SG D + +W+ Sbjct: 531 DNTIKLWDVKTGK-----CIRTQFGHVEGV----WDIAADNF---RIISGSHDGSIKVWD 578 Query: 397 LHTGEVAGTMKGHTSQ 444 L +G+ T G Q Sbjct: 579 LQSGKCMHTFNGRRLQ 594
>YAGE_SCHPO (Q9UTN4) Hypothetical WD-repeat protein C12G12.14c in chromosome I| Length = 509 Score = 41.6 bits (96), Expect = 0.001 Identities = 28/110 (25%), Positives = 44/110 (40%), Gaps = 1/110 (0%) Frame = +1 Query: 145 LHGHEDDVRGICIC-GDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVW 321 + HE +VR + D T+S D +++ W H + L GH V + W Sbjct: 160 VQAHEMEVRDVAFSPNDSKFVTASDDGSLKVWNFHMSTEE-----LKLTGHGWDVKTVDW 214 Query: 322 APPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDN 471 P +G + SG D V W+ TG T+ GH + + + N Sbjct: 215 HPS-----KGLLASGSKDNLVKFWDPRTGTCIATLHGHKNTIMQASFQKN 259
>WDR3_HUMAN (Q9UNX4) WD-repeat protein 3| Length = 943 Score = 41.6 bits (96), Expect = 0.001 Identities = 35/124 (28%), Positives = 56/124 (45%), Gaps = 6/124 (4%) Frame = +1 Query: 145 LHGHEDDVRGICICGDVG-----VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVG 309 L+GH+ V IC D+ +AT S D+ V+ W K+L H V Sbjct: 587 LYGHKLPV----ICMDISHDGALIATGSADRNVKIWGLDFGD-----CHKSLFAHDDSVM 637 Query: 310 PMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGD-IIS 486 + + P S F + G D ++ W+ E T++GH ++ LA+ +GD ++S Sbjct: 638 YLQFVPKSHLF-----FTAGKDHKIKQWDADKFEHIQTLEGHHQEIWCLAVSPSGDYVVS 692 Query: 487 SSMD 498 SS D Sbjct: 693 SSHD 696 Score = 33.1 bits (74), Expect = 0.43 Identities = 15/36 (41%), Positives = 21/36 (58%) Frame = +1 Query: 355 IVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAI 462 +V+ G DT V W+L T TM GH ++V GL + Sbjct: 164 LVTSGKDTMVKWWDLDTQHCFKTMVGHRTEVWGLVL 199 Score = 28.9 bits (63), Expect = 8.1 Identities = 13/51 (25%), Positives = 26/51 (50%), Gaps = 1/51 (1%) Frame = +1 Query: 349 GAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVT-GLAIDDNGDIISSSMD 498 G + SG DT +++W++ +KGH +T L + + +++S D Sbjct: 120 GRLASGSKDTDIIVWDVINESGLYRLKGHKDAITQALFLREKNLLVTSGKD 170
>HIR1_YEAST (P32479) Histone transcription regulator 1| Length = 788 Score = 41.6 bits (96), Expect = 0.001 Identities = 27/111 (24%), Positives = 47/111 (42%), Gaps = 11/111 (9%) Frame = +1 Query: 199 VATSSRDKTVRFWTQHPEK-----------KREYVLSKTLVGHSSFVGPMVWAPPSDRFP 345 +A+ S D+ + W E+ + + + K LV H + + + WAP S Sbjct: 42 LASGSDDRILLIWALDEEQSSQPAFGSEHEREHWTVRKRLVAHDNDIQDICWAPDSS--- 98 Query: 346 EGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSSMD 498 +V+ G+D V++WN T E H S V G+ D +++ D Sbjct: 99 --ILVTVGLDRSVIVWNGSTFEKLKRFDVHQSLVKGVVFDPANKYFATTSD 147
>YIRF_SCHPO (Q9P7I3) Hypothetical WD-repeat protein C664.15 in chromosome I| Length = 651 Score = 41.6 bits (96), Expect = 0.001 Identities = 36/145 (24%), Positives = 55/145 (37%), Gaps = 22/145 (15%) Frame = +1 Query: 130 HLSAQLHGHEDDVRGICICGDVG-VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFV 306 +L Q H + + + G +AT+S DKTV+ W V +L GHS +V Sbjct: 323 NLVKQFQAHSEYITSLDFSHPFGTLATASTDKTVKVWDM-----AGVVYLGSLKGHSDYV 377 Query: 307 GPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLH---------------------TGEVAGT 423 + + I +G MDT V LWNL Sbjct: 378 SCLA-------IQDSFIATGSMDTTVRLWNLDNDVLHKDNPVEESLNSPPDQPVDNATNV 430 Query: 424 MKGHTSQVTGLAIDDNGDIISSSMD 498 + HT+ VT LA+ + +I+ + D Sbjct: 431 LTSHTAPVTALALSSDDVLITGADD 455 Score = 39.7 bits (91), Expect = 0.005 Identities = 32/129 (24%), Positives = 57/129 (44%), Gaps = 11/129 (8%) Frame = +1 Query: 145 LHGHEDDVRGICICGDVGVATSSRDKTVRFW---TQHPEKKREYVLSKTLVGHSSFVGPM 315 L H V + + D + T + DKTVR W T + ++V ++T H + + Sbjct: 431 LTSHTAPVTALALSSDDVLITGADDKTVRQWDIVTGRCIQTLDFVWAET---HDTSTSQI 487 Query: 316 VWAPPSDRFP--------EGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDN 471 + + + P + A+ SG +D + +W+L G + GHT+ ++ L D N Sbjct: 488 LVSDTYKQEPFIRALDCLDAAVASGTVDGLIRIWDLRIGLPVRSFIGHTAPISSLQFDSN 547 Query: 472 GDIISSSMD 498 + S S D Sbjct: 548 -HLYSGSYD 555
>HAT2_NEUCR (Q7S7N3) Histone acetyltransferase type B subunit 2 (EC 2.3.1.48)| Length = 564 Score = 41.6 bits (96), Expect = 0.001 Identities = 33/104 (31%), Positives = 47/104 (45%), Gaps = 3/104 (2%) Frame = +1 Query: 97 VRRPAPLMAAYHLSAQLHGHEDDVRGICICGDVG--VATSSRDKTVRFWTQHPEKKREYV 270 VRRP AA +GH D + + V +AT+S DKT+ W K + + Sbjct: 271 VRRPETDKAAI---VARNGHSDAINALAFNPRVETIIATASADKTIGIWDMRNMKSKVH- 326 Query: 271 LSKTLVGHSSFVGPMVWAPPSDRFPEGAIV-SGGMDTQVLLWNL 399 TL GH V + W P E AI+ SG D ++L W++ Sbjct: 327 ---TLEGHQDAVTSLEWHP-----TESAILGSGSYDRRLLFWDI 362 Score = 31.6 bits (70), Expect = 1.2 Identities = 20/49 (40%), Positives = 25/49 (51%) Frame = +1 Query: 283 LVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMK 429 L+GH + W P EG +V+G D VLLW+L T E GT K Sbjct: 187 LIGHKEEGFGLNWNPHE----EGCLVTGSEDKTVLLWDLKTYE--GTSK 229
>WSB1_FUGRU (Q9W5Z5) WD repeat and SOCS box-containing protein 1 (WSB-1)| Length = 427 Score = 41.6 bits (96), Expect = 0.001 Identities = 31/122 (25%), Positives = 55/122 (45%), Gaps = 2/122 (1%) Frame = +1 Query: 133 LSAQLHGHEDDVRGICIC--GDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFV 306 L L H D VR + G + + ++S DK +R W + K + + K L GH + V Sbjct: 167 LLLNLMDHTDIVRDLTFAPDGSLMLVSASTDKKLRVW----DLKDDGNMVKVLWGHPNRV 222 Query: 307 GPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIIS 486 ++P S + S G VLLWN+ + ++GH + V +G +++ Sbjct: 223 YSSAFSPDSS-----VLCSVGASKAVLLWNMDKYTLIRKLEGHHNDVVSCEFSPDGALLA 277 Query: 487 SS 492 ++ Sbjct: 278 TA 279
>MORG1_RAT (Q5BLX8) Mitogen-activated protein kinase organizer 1 (MAPK| organizer 1) Length = 315 Score = 41.6 bits (96), Expect = 0.001 Identities = 28/99 (28%), Positives = 44/99 (44%), Gaps = 1/99 (1%) Frame = +1 Query: 205 TSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDTQV 384 T DKT++ W L +T GH V + F + SGG D V Sbjct: 42 TCGSDKTLKLWNP-----LRGTLLRTYSGHGYEV-----LDAAGSFDNSHLCSGGGDKTV 91 Query: 385 LLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDII-SSSMD 498 +LW++ TG+V +GH +V + ++ +I S S+D Sbjct: 92 VLWDVATGQVVRKFRGHAGKVNTVQFNEEATVILSGSID 130
>MORG1_MOUSE (Q9DAJ4) Mitogen-activated protein kinase organizer 1 (MAPK| organizer 1) Length = 315 Score = 41.6 bits (96), Expect = 0.001 Identities = 28/99 (28%), Positives = 44/99 (44%), Gaps = 1/99 (1%) Frame = +1 Query: 205 TSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDTQV 384 T DKT++ W L +T GH V + F + SGG D V Sbjct: 42 TCGSDKTLKLWNP-----LRGTLLRTYSGHGYEV-----LDAAGSFDNSHLCSGGGDKTV 91 Query: 385 LLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDII-SSSMD 498 +LW++ TG+V +GH +V + ++ +I S S+D Sbjct: 92 VLWDVATGQVVRKFRGHAGKVNTVQFNEEATVILSGSID 130
>KTNB1_STRPU (O61585) Katanin p80 WD40-containing subunit B1 (Katanin p80| subunit B1) (p80 katanin) Length = 690 Score = 41.6 bits (96), Expect = 0.001 Identities = 34/120 (28%), Positives = 55/120 (45%), Gaps = 5/120 (4%) Frame = +1 Query: 145 LHGHEDDVRGICICGDVG-----VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVG 309 L GH + +R C D VA+ S D V+ W + +R+ + T GHS V Sbjct: 97 LTGHRNSIR----CMDFHPFGEFVASGSTDTNVKLW----DVRRKGCIY-TYKGHSDQVN 147 Query: 310 PMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISS 489 + ++P +V+ DT + LW+L G++ K HT VTG+ N +++S Sbjct: 148 MIKFSPDGKW-----LVTASEDTTIKLWDLTMGKLFQEFKNHTGGVTGIEFHPNEFLLAS 202 Score = 36.6 bits (83), Expect = 0.039 Identities = 24/76 (31%), Positives = 39/76 (51%) Frame = +1 Query: 256 KREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGH 435 KR + L + LV HSS V + P S R +V+GG D +V LW + ++ GH Sbjct: 4 KRAWKLQE-LVAHSSNVNCLALGPMSGR----VMVTGGEDKKVNLWAVGKQNCIISLSGH 58 Query: 436 TSQVTGLAIDDNGDII 483 TS V + + + +++ Sbjct: 59 TSPVDSVKFNSSEELV 74
>KTNB1_BRARE (Q7ZUV2) Katanin p80 WD40-containing subunit B1 homolog| Length = 694 Score = 41.2 bits (95), Expect = 0.002 Identities = 28/118 (23%), Positives = 54/118 (45%), Gaps = 2/118 (1%) Frame = +1 Query: 142 QLHGHEDDVRGICICGDVG--VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPM 315 ++ H +V + + G +AT D V W K ++S L GH+S VG + Sbjct: 15 EIVAHSSNVSSLVLGKSSGRLLATGGEDCRVNIWAV---SKPNCIMS--LTGHTSAVGCI 69 Query: 316 VWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISS 489 + +R +V+G + + LW+L ++ T+ GH + ++ L G+ ++S Sbjct: 70 QFNSSEER-----VVAGSLSGSLRLWDLEAAKILRTLMGHKASISSLDFHPMGEYLAS 122 Score = 40.4 bits (93), Expect = 0.003 Identities = 25/100 (25%), Positives = 45/100 (45%) Frame = +1 Query: 199 VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDT 378 V S ++R W K + +TL+GH + + + + P + + SG +D+ Sbjct: 78 VVAGSLSGSLRLWDLEAAK-----ILRTLMGHKASISSLDFHPMGEY-----LASGSVDS 127 Query: 379 QVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSSMD 498 + LW++ KGHT V LA +G ++S+ D Sbjct: 128 NIKLWDVRRKGCVFRYKGHTQAVRCLAFSPDGKWLASASD 167
>MORG1_HUMAN (Q9BRX9) Mitogen-activated protein kinase organizer 1 (MAPK| organizer 1) Length = 315 Score = 41.2 bits (95), Expect = 0.002 Identities = 27/99 (27%), Positives = 45/99 (45%), Gaps = 1/99 (1%) Frame = +1 Query: 205 TSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDTQV 384 T DKT++ W L +T GH V + F ++ SGG D V Sbjct: 42 TCGSDKTLKLWNP-----LRGTLLRTYSGHGYEV-----LDAAGSFDNSSLCSGGGDKAV 91 Query: 385 LLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDII-SSSMD 498 +LW++ +G+V +GH +V + ++ +I S S+D Sbjct: 92 VLWDVASGQVVRKFRGHAGKVNTVQFNEEATVILSGSID 130
>YMZ2_YEAST (Q03177) Hypothetical 94.3 kDa Trp-Asp repeats-containing protein| in SNZ1-YPK2 intergenic region Length = 834 Score = 41.2 bits (95), Expect = 0.002 Identities = 29/88 (32%), Positives = 45/88 (51%) Frame = +1 Query: 154 HEDDVRGICICGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPS 333 H DV I + + ++S DKTV+ W HP++K KT + H FV + + P Sbjct: 277 HVQDVLDINWSKNNFILSASMDKTVKLW--HPDRKNSL---KTFI-HPDFVTCVEFHPTD 330 Query: 334 DRFPEGAIVSGGMDTQVLLWNLHTGEVA 417 DRF +SG +D + LW++ EV+ Sbjct: 331 DRF----FISGCLDHKCRLWSILDDEVS 354
>STRN3_HUMAN (Q13033) Striatin-3 (Cell-cycle autoantigen SG2NA) (S/G2 antigen)| Length = 797 Score = 41.2 bits (95), Expect = 0.002 Identities = 36/134 (26%), Positives = 57/134 (42%), Gaps = 16/134 (11%) Frame = +1 Query: 145 LHGHEDDVRGICICG-DVGVATSSRDKTVRFWTQH---PEKKREYVLSKTLVGHSSFVGP 312 L H D VR + + + T+S D T++ W P KK + + + + +GP Sbjct: 476 LRSHFDGVRALAFHPVEPVLVTASEDHTLKLWNLQKTVPAKKSASLDVEPIYTFRAHIGP 535 Query: 313 MVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEV-----------AGTMKGHTSQVTGLA 459 ++ S + SGG+D + WN+ + V AGT+ GHT V GLA Sbjct: 536 VLSLAISSNGEQ--CFSGGIDATIQWWNMPSPSVDPYDTYEPNVLAGTLVGHTDAVWGLA 593 Query: 460 IDD-NGDIISSSMD 498 ++S S D Sbjct: 594 YSGIKNQLLSCSAD 607 Score = 31.6 bits (70), Expect = 1.2 Identities = 16/44 (36%), Positives = 25/44 (56%), Gaps = 1/44 (2%) Frame = +1 Query: 373 DTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNG-DIISSSMDC 501 D + ++ TG++ +M H VT LA+D NG ++S S DC Sbjct: 702 DRHIKFFDNKTGKMIHSMVAHLDAVTSLAVDPNGIYLMSGSHDC 745
>GBB2_RAT (P54313) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 2 (Transducin beta chain 2) (G protein beta 2 subunit) Length = 339 Score = 41.2 bits (95), Expect = 0.002 Identities = 32/122 (26%), Positives = 47/122 (38%) Frame = +1 Query: 133 LSAQLHGHEDDVRGICICGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGP 312 +S +L GH + D + TSS D T W ++ + GHS V Sbjct: 134 VSRELPGHTGYLSCCRFLDDNQIITSSGDTTCALWDIETGQQ-----TVGFAGHSGDVMS 188 Query: 313 MVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSS 492 + AP F VSG D + LW++ T GH S + +A NG ++ Sbjct: 189 LSLAPDGRTF-----VSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTG 243 Query: 493 MD 498 D Sbjct: 244 SD 245 Score = 33.5 bits (75), Expect = 0.33 Identities = 28/153 (18%), Positives = 56/153 (36%), Gaps = 40/153 (26%) Frame = +1 Query: 151 GHEDDVRGICICGDVGVATSSR-DKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAP 327 GH DV + + D S D +++ W R+ + +T +GH S + + + P Sbjct: 181 GHSGDVMSLSLAPDGRTFVSGACDASIKLWDV-----RDSMCRQTFIGHESDINAVAFFP 235 Query: 328 PSDRFPEGA---------------------------------------IVSGGMDTQVLL 390 F G+ +++G D + Sbjct: 236 NGYAFTTGSDDATCRLFDLRADQELLMYSHDNIICGITSVAFSRSGRLLLAGYDDFNCNI 295 Query: 391 WNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISS 489 W+ G+ AG + GH ++V+ L + D+G +++ Sbjct: 296 WDAMKGDRAGVLAGHDNRVSCLGVTDDGMAVAT 328
>GBB2_MOUSE (P62880) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 2 (Transducin beta chain 2) (G protein beta 2 subunit) Length = 339 Score = 41.2 bits (95), Expect = 0.002 Identities = 32/122 (26%), Positives = 47/122 (38%) Frame = +1 Query: 133 LSAQLHGHEDDVRGICICGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGP 312 +S +L GH + D + TSS D T W ++ + GHS V Sbjct: 134 VSRELPGHTGYLSCCRFLDDNQIITSSGDTTCALWDIETGQQ-----TVGFAGHSGDVMS 188 Query: 313 MVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSS 492 + AP F VSG D + LW++ T GH S + +A NG ++ Sbjct: 189 LSLAPDGRTF-----VSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTG 243 Query: 493 MD 498 D Sbjct: 244 SD 245 Score = 33.5 bits (75), Expect = 0.33 Identities = 28/153 (18%), Positives = 56/153 (36%), Gaps = 40/153 (26%) Frame = +1 Query: 151 GHEDDVRGICICGDVGVATSSR-DKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAP 327 GH DV + + D S D +++ W R+ + +T +GH S + + + P Sbjct: 181 GHSGDVMSLSLAPDGRTFVSGACDASIKLWDV-----RDSMCRQTFIGHESDINAVAFFP 235 Query: 328 PSDRFPEGA---------------------------------------IVSGGMDTQVLL 390 F G+ +++G D + Sbjct: 236 NGYAFTTGSDDATCRLFDLRADQELLMYSHDNIICGITSVAFSRSGRLLLAGYDDFNCNI 295 Query: 391 WNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISS 489 W+ G+ AG + GH ++V+ L + D+G +++ Sbjct: 296 WDAMKGDRAGVLAGHDNRVSCLGVTDDGMAVAT 328
>GBB2_HUMAN (P62879) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 2 (Transducin beta chain 2) (G protein beta 2 subunit) Length = 339 Score = 41.2 bits (95), Expect = 0.002 Identities = 32/122 (26%), Positives = 47/122 (38%) Frame = +1 Query: 133 LSAQLHGHEDDVRGICICGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGP 312 +S +L GH + D + TSS D T W ++ + GHS V Sbjct: 134 VSRELPGHTGYLSCCRFLDDNQIITSSGDTTCALWDIETGQQ-----TVGFAGHSGDVMS 188 Query: 313 MVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSS 492 + AP F VSG D + LW++ T GH S + +A NG ++ Sbjct: 189 LSLAPDGRTF-----VSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTG 243 Query: 493 MD 498 D Sbjct: 244 SD 245 Score = 33.5 bits (75), Expect = 0.33 Identities = 28/153 (18%), Positives = 56/153 (36%), Gaps = 40/153 (26%) Frame = +1 Query: 151 GHEDDVRGICICGDVGVATSSR-DKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAP 327 GH DV + + D S D +++ W R+ + +T +GH S + + + P Sbjct: 181 GHSGDVMSLSLAPDGRTFVSGACDASIKLWDV-----RDSMCRQTFIGHESDINAVAFFP 235 Query: 328 PSDRFPEGA---------------------------------------IVSGGMDTQVLL 390 F G+ +++G D + Sbjct: 236 NGYAFTTGSDDATCRLFDLRADQELLMYSHDNIICGITSVAFSRSGRLLLAGYDDFNCNI 295 Query: 391 WNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISS 489 W+ G+ AG + GH ++V+ L + D+G +++ Sbjct: 296 WDAMKGDRAGVLAGHDNRVSCLGVTDDGMAVAT 328
>GBB2_BOVIN (P11017) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 2 (Transducin beta chain 2) (G protein beta 2 subunit) (Fragment) Length = 326 Score = 41.2 bits (95), Expect = 0.002 Identities = 32/122 (26%), Positives = 47/122 (38%) Frame = +1 Query: 133 LSAQLHGHEDDVRGICICGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGP 312 +S +L GH + D + TSS D T W ++ + GHS V Sbjct: 121 VSRELPGHTGYLSCCRFLDDNQIITSSGDTTCALWDIETGQQ-----TVGFAGHSGDVMS 175 Query: 313 MVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSS 492 + AP F VSG D + LW++ T GH S + +A NG ++ Sbjct: 176 LSLAPDGRTF-----VSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTG 230 Query: 493 MD 498 D Sbjct: 231 SD 232 Score = 33.5 bits (75), Expect = 0.33 Identities = 28/153 (18%), Positives = 56/153 (36%), Gaps = 40/153 (26%) Frame = +1 Query: 151 GHEDDVRGICICGDVGVATSSR-DKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAP 327 GH DV + + D S D +++ W R+ + +T +GH S + + + P Sbjct: 168 GHSGDVMSLSLAPDGRTFVSGACDASIKLWDV-----RDSMCRQTFIGHESDINAVAFFP 222 Query: 328 PSDRFPEGA---------------------------------------IVSGGMDTQVLL 390 F G+ +++G D + Sbjct: 223 NGYAFTTGSDDATCRLFDLRADQELLMYSHDNIICGITSVAFSRSGRLLLAGYDDFNCNI 282 Query: 391 WNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISS 489 W+ G+ AG + GH ++V+ L + D+G +++ Sbjct: 283 WDAMKGDRAGVLAGHDNRVSCLGVTDDGMAVAT 315
>TUP1_YEAST (P16649) Glucose repression regulatory protein TUP1 (Flocculation| suppressor protein) (Repressor AER2) Length = 713 Score = 40.8 bits (94), Expect = 0.002 Identities = 31/112 (27%), Positives = 50/112 (44%), Gaps = 8/112 (7%) Frame = +1 Query: 151 GHEDDVRGICICGD-VGVATSSRDKTVRFWT-QHPEKKREY------VLSKTLVGHSSFV 306 GH+D V + D V + S D++V+ W Q+ K + T +GH FV Sbjct: 574 GHKDSVYSVVFTRDGQSVVSGSLDRSVKLWNLQNANNKSDSKTPNSGTCEVTYIGHKDFV 633 Query: 307 GPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAI 462 V +D + I+SG D VL W+ +G ++GH + V +A+ Sbjct: 634 -LSVATTQNDEY----ILSGSKDRGVLFWDKKSGNPLLMLQGHRNSVISVAV 680 Score = 38.5 bits (88), Expect = 0.010 Identities = 31/114 (27%), Positives = 52/114 (45%), Gaps = 3/114 (2%) Frame = +1 Query: 166 VRGICICGDVG-VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRF 342 +R +C D +AT + D+ +R W K + L GH + + + P D+ Sbjct: 446 IRSVCFSPDGKFLATGAEDRLIRIWDIENRK-----IVMILQGHEQDIYSLDYFPSGDK- 499 Query: 343 PEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAID--DNGDIISSSMD 498 +VSG D V +W+L TG+ + T+ VT +A+ D I + S+D Sbjct: 500 ----LVSGSGDRTVRIWDLRTGQCSLTLSIEDG-VTTVAVSPGDGKYIAAGSLD 548
>KTNB1_ARATH (Q8H0T9) Katanin p80 WD40-containing subunit B1 homolog 1| Length = 837 Score = 40.8 bits (94), Expect = 0.002 Identities = 29/111 (26%), Positives = 47/111 (42%), Gaps = 1/111 (0%) Frame = +1 Query: 145 LHGHEDDVRGICI-CGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVW 321 L+GH + + +V VA + T++ W K + +TL GH S + + Sbjct: 55 LYGHSSGIDSVTFDASEVLVAAGAASGTIKLWDLEEAK-----IVRTLTGHRSNCISVDF 109 Query: 322 APPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNG 474 P + F SG +DT + +W++ T KGHT V L +G Sbjct: 110 HPFGEFF-----ASGSLDTNLKIWDIRKKGCIHTYKGHTRGVNVLRFTPDG 155 Score = 30.4 bits (67), Expect = 2.8 Identities = 23/97 (23%), Positives = 38/97 (39%) Frame = +1 Query: 199 VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDT 378 + T D V W K +LS L GHSS + + + E + +G Sbjct: 32 LVTGGEDHKVNLWAIG---KPNAILS--LYGHSSGIDSVTFDAS-----EVLVAAGAASG 81 Query: 379 QVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISS 489 + LW+L ++ T+ GH S + G+ +S Sbjct: 82 TIKLWDLEEAKIVRTLTGHRSNCISVDFHPFGEFFAS 118
>PLRG1_RAT (Q9WUC8) Pleiotropic regulator 1| Length = 514 Score = 40.8 bits (94), Expect = 0.002 Identities = 36/114 (31%), Positives = 51/114 (44%), Gaps = 1/114 (0%) Frame = +1 Query: 145 LHGHEDDVRGICI-CGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVW 321 + GH VR I + G+ T S D+T++ W K L +L GH S V ++ Sbjct: 200 ISGHLGWVRCIAVEPGNQWFVTGSADRTIKIWDLASGK-----LKLSLTGHISTVRGVI- 253 Query: 322 APPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDII 483 S R P + S G D QV W+L +V GH S V GL + D++ Sbjct: 254 --VSTRSPY--LFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVL 303 Score = 33.1 bits (74), Expect = 0.43 Identities = 19/81 (23%), Positives = 38/81 (46%) Frame = +1 Query: 247 PEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTM 426 P+ + L + + GH +V + P + F V+G D + +W+L +G++ ++ Sbjct: 188 PQWHPPWKLYRVISGHLGWVRCIAVEPGNQWF-----VTGSADRTIKIWDLASGKLKLSL 242 Query: 427 KGHTSQVTGLAIDDNGDIISS 489 GH S V G+ + + S Sbjct: 243 TGHISTVRGVIVSTRSPYLFS 263 Score = 32.3 bits (72), Expect = 0.73 Identities = 29/111 (26%), Positives = 45/111 (40%), Gaps = 1/111 (0%) Frame = +1 Query: 118 MAAYHLSAQLHGHEDDVRGICICGDVGVATS-SRDKTVRFWTQHPEKKREYVLSKTLVGH 294 +A+ L L GH VRG+ + S DK V+ W K + + GH Sbjct: 233 LASGKLKLSLTGHISTVRGVIVSTRSPYLFSCGEDKQVKCWDLEYNK-----VIRHYHGH 287 Query: 295 SSFVGPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQV 447 S V + P D +V+ D+ +W++ T T+ GHT+ V Sbjct: 288 LSAVYGLDLHPTID-----VLVTCSRDSTARIWDVRTKASVHTLSGHTNAV 333
>PLRG1_HUMAN (O43660) Pleiotropic regulator 1| Length = 514 Score = 40.8 bits (94), Expect = 0.002 Identities = 36/114 (31%), Positives = 51/114 (44%), Gaps = 1/114 (0%) Frame = +1 Query: 145 LHGHEDDVRGICI-CGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVW 321 + GH VR I + G+ T S D+T++ W K L +L GH S V ++ Sbjct: 200 ISGHLGWVRCIAVEPGNQWFVTGSADRTIKIWDLASGK-----LKLSLTGHISTVRGVI- 253 Query: 322 APPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDII 483 S R P + S G D QV W+L +V GH S V GL + D++ Sbjct: 254 --VSTRSPY--LFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVL 303 Score = 33.1 bits (74), Expect = 0.43 Identities = 19/81 (23%), Positives = 38/81 (46%) Frame = +1 Query: 247 PEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTM 426 P+ + L + + GH +V + P + F V+G D + +W+L +G++ ++ Sbjct: 188 PQWHPPWKLYRVISGHLGWVRCIAVEPGNQWF-----VTGSADRTIKIWDLASGKLKLSL 242 Query: 427 KGHTSQVTGLAIDDNGDIISS 489 GH S V G+ + + S Sbjct: 243 TGHISTVRGVIVSTRSPYLFS 263 Score = 32.3 bits (72), Expect = 0.73 Identities = 29/111 (26%), Positives = 45/111 (40%), Gaps = 1/111 (0%) Frame = +1 Query: 118 MAAYHLSAQLHGHEDDVRGICICGDVGVATS-SRDKTVRFWTQHPEKKREYVLSKTLVGH 294 +A+ L L GH VRG+ + S DK V+ W K + + GH Sbjct: 233 LASGKLKLSLTGHISTVRGVIVSTRSPYLFSCGEDKQVKCWDLEYNK-----VIRHYHGH 287 Query: 295 SSFVGPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQV 447 S V + P D +V+ D+ +W++ T T+ GHT+ V Sbjct: 288 LSAVYGLDLHPTID-----VLVTCSRDSTARIWDVRTKASVHTLSGHTNAV 333
>GBB_LYMST (Q08706) Guanine nucleotide-binding protein beta subunit| Length = 341 Score = 40.8 bits (94), Expect = 0.002 Identities = 29/122 (23%), Positives = 47/122 (38%) Frame = +1 Query: 133 LSAQLHGHEDDVRGICICGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGP 312 +S +L GH + D + TSS D + W ++ + + GH+ V Sbjct: 136 VSRELPGHTGYLSCCRFIDDNSIVTSSGDMSCALWDIETGQQ-----TTSFTGHTGDVMS 190 Query: 313 MVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSS 492 + +P F VSG D LW++ G T GH S + + NG ++ Sbjct: 191 LSTSPDFRTF-----VSGACDASAKLWDVRDGMCKQTFSGHESDINAITYFPNGHAFATG 245 Query: 493 MD 498 D Sbjct: 246 SD 247
>CORO_CAEEL (Q21624) Coronin-like protein cor-1| Length = 605 Score = 40.8 bits (94), Expect = 0.002 Identities = 24/95 (25%), Positives = 45/95 (47%), Gaps = 3/95 (3%) Frame = +1 Query: 199 VATSSRDKTVRFWTQHPEKKREYVLSKT---LVGHSSFVGPMVWAPPSDRFPEGAIVSGG 369 +A+ S D T + W P++ LS+ L GH V + W P ++ +++ G Sbjct: 95 IASCSEDTTCKVWVI-PDRGLNRNLSEPAVELTGHQKRVNTIAWHPVANN----VLLTAG 149 Query: 370 MDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNG 474 + + +WN+ TGE + GH Q+ + + +G Sbjct: 150 GENVMFMWNVGTGEALLEISGHPDQIWSINFNFDG 184
>PLRG1_MOUSE (Q922V4) Pleiotropic regulator 1| Length = 513 Score = 40.8 bits (94), Expect = 0.002 Identities = 36/114 (31%), Positives = 51/114 (44%), Gaps = 1/114 (0%) Frame = +1 Query: 145 LHGHEDDVRGICI-CGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVW 321 + GH VR I + G+ T S D+T++ W K L +L GH S V ++ Sbjct: 199 ISGHLGWVRCIAVEPGNQWFVTGSADRTIKIWDLASGK-----LKLSLTGHISTVRGVI- 252 Query: 322 APPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDII 483 S R P + S G D QV W+L +V GH S V GL + D++ Sbjct: 253 --VSTRSPY--LFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTLDVL 302 Score = 33.1 bits (74), Expect = 0.43 Identities = 19/81 (23%), Positives = 38/81 (46%) Frame = +1 Query: 247 PEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTM 426 P+ + L + + GH +V + P + F V+G D + +W+L +G++ ++ Sbjct: 187 PQWHPPWKLYRVISGHLGWVRCIAVEPGNQWF-----VTGSADRTIKIWDLASGKLKLSL 241 Query: 427 KGHTSQVTGLAIDDNGDIISS 489 GH S V G+ + + S Sbjct: 242 TGHISTVRGVIVSTRSPYLFS 262 Score = 32.3 bits (72), Expect = 0.73 Identities = 29/111 (26%), Positives = 45/111 (40%), Gaps = 1/111 (0%) Frame = +1 Query: 118 MAAYHLSAQLHGHEDDVRGICICGDVGVATS-SRDKTVRFWTQHPEKKREYVLSKTLVGH 294 +A+ L L GH VRG+ + S DK V+ W K + + GH Sbjct: 232 LASGKLKLSLTGHISTVRGVIVSTRSPYLFSCGEDKQVKCWDLEYNK-----VIRHYHGH 286 Query: 295 SSFVGPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQV 447 S V + P D +V+ D+ +W++ T T+ GHT+ V Sbjct: 287 LSAVYGLDLHPTLD-----VLVTCSRDSTARIWDVRTKASVHTLSGHTNAV 332
>WDR33_HUMAN (Q9C0J8) WD-repeat protein 33 (WD-repeat protein WDC146)| Length = 1336 Score = 40.4 bits (93), Expect = 0.003 Identities = 32/105 (30%), Positives = 51/105 (48%), Gaps = 6/105 (5%) Frame = +1 Query: 202 ATSSRDKTVRFWTQ---HPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGM 372 AT S D TVR W H E+ L GH + V + W P +G +VSG Sbjct: 218 ATCSDDGTVRIWDFLRCHEER--------ILRGHGADVKCVDWHPT-----KGLVVSGSK 264 Query: 373 DTQ--VLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGD-IISSSMD 498 D+Q + W+ TG+ T+ H + V + ++ NG+ ++++S D Sbjct: 265 DSQQPIKFWDPKTGQSLATLHAHKNTVMEVKLNLNGNWLLTASRD 309 Score = 36.2 bits (82), Expect = 0.051 Identities = 34/121 (28%), Positives = 47/121 (38%), Gaps = 4/121 (3%) Frame = +1 Query: 139 AQLHGHEDDVRGICI-CGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPM 315 A LH H++ V + + + T+SRD + + K+ V GH + Sbjct: 282 ATLHAHKNTVMEVKLNLNGNWLLTASRDHLCKLFDIRNLKEELQVFR----GHKKEATAV 337 Query: 316 VWAPPSDRFPEGAIVSGGMDTQVLLWNLHTG---EVAGTMKGHTSQVTGLAIDDNGDIIS 486 W P EG SGG D +L W H G EV G H + LA G I+ Sbjct: 338 AWHPVH----EGLFASGGSDGSLLFW--HVGVEKEVGGMEMAHEGMIWSLAWHPLGHILC 391 Query: 487 S 489 S Sbjct: 392 S 392
>POF11_SCHPO (Q09855) F-box/WD-repeat protein pof11| Length = 506 Score = 40.4 bits (93), Expect = 0.003 Identities = 35/115 (30%), Positives = 49/115 (42%), Gaps = 3/115 (2%) Frame = +1 Query: 130 HLSAQLHGHEDDVRGICICGDVG--VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSF 303 H +H H+ RGI G + + S D T+R + K L + L GH Sbjct: 380 HCIRIIHAHQ---RGIACAQYNGKFIVSGSSDLTIRIFEASSGK-----LLRMLQGHEDL 431 Query: 304 VGPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTM-KGHTSQVTGLAID 465 + + RF + IVSGG D V +WN +TGE + S+V GL D Sbjct: 432 IRTV-------RFNDEKIVSGGYDGTVRIWNFNTGEQHCVLHNSRNSRVFGLQFD 479 Score = 39.7 bits (91), Expect = 0.005 Identities = 29/100 (29%), Positives = 48/100 (48%) Frame = +1 Query: 199 VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDT 378 + + S+D+TV W + ++L K L GHS V + + + +VSG D+ Sbjct: 234 MVSGSKDRTVSVW----DVNSRFILYK-LYGHSGSVLCLDFCRRRN-----LLVSGSSDS 283 Query: 379 QVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSSMD 498 +++W+ GHT V G+ + +N IISSS D Sbjct: 284 TIIIWDWQNRRPLKVYFGHTDNVLGVVVSEN-YIISSSRD 322 Score = 37.0 bits (84), Expect = 0.030 Identities = 31/117 (26%), Positives = 50/117 (42%), Gaps = 1/117 (0%) Frame = +1 Query: 151 GHEDDVRGICICGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPP 330 GH D+V G+ + + + +SSRD T R W E + L GH + V + ++ Sbjct: 301 GHTDNVLGVVVSENY-IISSSRDHTARVWRLDATSPAEACM-HVLRGHLASVNSVQYSSK 358 Query: 331 SDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGD-IISSSMD 498 + G IV+ D + W++ TG + H + NG I+S S D Sbjct: 359 T-----GLIVTASSDRTLRTWDITTGHCIRIIHAHQRGIA--CAQYNGKFIVSGSSD 408
>WDR1_CHICK (O93277) WD-repeat protein 1 (Actin-interacting protein 1) (AIP1)| Length = 609 Score = 40.4 bits (93), Expect = 0.003 Identities = 20/49 (40%), Positives = 31/49 (63%), Gaps = 1/49 (2%) Frame = +1 Query: 355 IVSGGMDTQVLLWNLHTGEVAG-TMKGHTSQVTGLAIDDNGDIISSSMD 498 I SG D + W+ TGE G + KGHT+QV+ +A+D+ +++ SMD Sbjct: 339 IYSGSNDGHINYWDSDTGENDGFSGKGHTNQVSRMAVDEMDQLVTCSMD 387 Score = 34.7 bits (78), Expect = 0.15 Identities = 23/80 (28%), Positives = 36/80 (45%), Gaps = 2/80 (2%) Frame = +1 Query: 265 YVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKG--HT 438 YV GH + V + W+P ++ F SGGMD V +W + E + Sbjct: 524 YVEHNVFYGHHAKVVCIAWSPDNEHF-----ASGGMDMMVYVWTVSDPETRIKIPDAHRL 578 Query: 439 SQVTGLAIDDNGDIISSSMD 498 V+GLA D ++++S D Sbjct: 579 HHVSGLAWLDEHTLVTTSHD 598
>COR1A_BOVIN (Q92176) Coronin-1A (Coronin-like protein p57) (Coronin-like| protein A) (CLIPINA) (Tryptophan aspartate-containing coat protein) (TACO) Length = 461 Score = 40.4 bits (93), Expect = 0.003 Identities = 32/114 (28%), Positives = 52/114 (45%), Gaps = 5/114 (4%) Frame = +1 Query: 151 GHEDDVRGICIC--GDVGVATSSRDKTVRFWTQHPEKKREYVLSK---TLVGHSSFVGPM 315 GH V I C D +A+ S D +V W + P+ L + TL GH+ VG + Sbjct: 79 GHTAPVLDIAWCPHNDNVIASGSEDCSVMVW-EIPDGGLTLPLREPVVTLEGHTKRVGIV 137 Query: 316 VWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGD 477 W P + + ++S G D +L+W++ TG T+ T ++D + D Sbjct: 138 AWHPTA----QNVLLSAGCDNVILVWDVGTGVAVLTLGSDVHPDTIYSVDWSRD 187
>HAT2_GIBZE (Q4I7L0) Histone acetyltransferase type B subunit 2 (EC 2.3.1.48)| Length = 423 Score = 40.4 bits (93), Expect = 0.003 Identities = 25/85 (29%), Positives = 40/85 (47%), Gaps = 2/85 (2%) Frame = +1 Query: 151 GHEDDVRGICIC--GDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWA 324 GH D + + +V VAT+S DKT+ W K++ + TL GH+ V + W Sbjct: 271 GHLDAINALAFNPNSEVLVATASADKTIGIWDLRNVKEKVH----TLEGHNDAVTSLAWH 326 Query: 325 PPSDRFPEGAIVSGGMDTQVLLWNL 399 P G + S D +++ W+L Sbjct: 327 PTE----AGILGSASYDRRIIFWDL 347
>GBB1_CAEEL (P17343) Guanine nucleotide-binding protein beta subunit 1| Length = 340 Score = 40.4 bits (93), Expect = 0.003 Identities = 29/122 (23%), Positives = 47/122 (38%) Frame = +1 Query: 133 LSAQLHGHEDDVRGICICGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGP 312 +S +L GH + D + TSS D T W ++ GH+ V Sbjct: 135 VSRELPGHTGYLSCCRFLDDNQIVTSSGDMTCALWDIETGQQ-----CTAFTGHTGDVMS 189 Query: 313 MVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSS 492 + +P F +SG D LW++ G T GH S + +A +G+ ++ Sbjct: 190 LSLSPDFRTF-----ISGACDASAKLWDIRDGMCKQTFPGHESDINAVAFFPSGNAFATG 244 Query: 493 MD 498 D Sbjct: 245 SD 246
>GBB1_CAEBR (Q61ZF6) Guanine nucleotide-binding protein beta subunit 1| Length = 340 Score = 40.4 bits (93), Expect = 0.003 Identities = 29/122 (23%), Positives = 47/122 (38%) Frame = +1 Query: 133 LSAQLHGHEDDVRGICICGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGP 312 +S +L GH + D + TSS D T W ++ GH+ V Sbjct: 135 VSRELPGHTGYLSCCRFLDDNQIVTSSGDMTCALWDIETGQQ-----CTAFTGHTGDVMS 189 Query: 313 MVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSS 492 + +P F +SG D LW++ G T GH S + +A +G+ ++ Sbjct: 190 LSLSPDFRTF-----ISGACDASAKLWDIRDGMCKQTFPGHESDINAVAFFPSGNAFATG 244 Query: 493 MD 498 D Sbjct: 245 SD 246
>STTP1_MOUSE (Q91WG4) Stat3-interacting protein (StIP1)| Length = 831 Score = 40.4 bits (93), Expect = 0.003 Identities = 23/69 (33%), Positives = 35/69 (50%), Gaps = 2/69 (2%) Frame = +1 Query: 247 PEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGT- 423 P+KK V+ L GH++ V + W D P +VSGG D +V+ W L +V + Sbjct: 45 PQKK---VVITNLNGHTARVNCLQWIRTEDGSPSNELVSGGSDNRVIHWELENNQVLKSV 101 Query: 424 -MKGHTSQV 447 ++GH V Sbjct: 102 RLQGHEGPV 110
>GBB_SCHPO (Q10282) Guanine nucleotide-binding protein beta subunit| Length = 305 Score = 40.4 bits (93), Expect = 0.003 Identities = 31/120 (25%), Positives = 46/120 (38%), Gaps = 1/120 (0%) Frame = +1 Query: 142 QLHGHEDDVRGICICGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVW 321 +L GH V D + T S DKT FW K L GH + + + Sbjct: 101 ELVGHAGFVSCCKYVDDGHLLTGSGDKTCMFWDIEQAKA-----ISVLKGHEMDIVSLDF 155 Query: 322 APPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLA-IDDNGDIISSSMD 498 P + V+GG D LW+L T G+TS + ++ N D ++ + D Sbjct: 156 LPSNPNL----FVTGGCDKLAKLWDLRAAYCCATFPGNTSDINSISFFPSNADFVTGAED 211
>APAF_MOUSE (O88879) Apoptotic protease-activating factor 1 (Apaf-1)| Length = 1249 Score = 40.4 bits (93), Expect = 0.003 Identities = 32/116 (27%), Positives = 49/116 (42%), Gaps = 1/116 (0%) Frame = +1 Query: 145 LHGHEDDVRGICICGDVG-VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVW 321 + HED+V D +AT S DK V+ W K L T HS V + Sbjct: 653 IKAHEDEVLCCAFSSDDSYIATCSADKKVKIWDSATGK-----LVHTYDEHSEQVNCCHF 707 Query: 322 APPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISS 489 S+ + +G D + LW+L+ E TM GHT+ V + ++++S Sbjct: 708 TNSSNHL---LLATGSNDFFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDELLAS 760
>YNA6_YEAST (P41318) Hypothetical 34.0 kDa Trp-Asp repeats-containing protein| in SIS1-MRPL2 intergenic region Length = 303 Score = 40.4 bits (93), Expect = 0.003 Identities = 34/118 (28%), Positives = 50/118 (42%), Gaps = 3/118 (2%) Frame = +1 Query: 124 AYHLS--AQLHGHEDDVRGICICGDVG-VATSSRDKTVRFWTQHPEKKREYVLSKTLVGH 294 A HL + H + I + DV +AT S D T R W+ + K L TL GH Sbjct: 194 ASHLKPVTKFRAHSTYITRILLSSDVKHLATCSADHTARVWSIDDDFK----LETTLDGH 249 Query: 295 SSFVGPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDD 468 +V ++ S +V+ D V LW+L T E+ GH +A++D Sbjct: 250 QRWVWDCAFSADS-----AYLVTASSDHYVRLWDLSTREIVRQYGGHHKGAVCVALND 302
>PRP46_KLULA (Q6CKE8) Pre-mRNA-splicing factor PRP46 (Pre-mRNA-processing| protein 46) Length = 434 Score = 40.0 bits (92), Expect = 0.004 Identities = 36/126 (28%), Positives = 54/126 (42%), Gaps = 2/126 (1%) Frame = +1 Query: 121 AAYHLSAQLHGHEDDVRGICI--CGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGH 294 A + LS ++GH VR +C+ + AT S D T++ W K L TL+GH Sbjct: 110 APWKLSKVINGHTGWVRCVCVDPVDNEWFATGSNDTTIKIWDLAAGK-----LKITLIGH 164 Query: 295 SSFVGPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNG 474 V + S R P + S D V W+L GH S V + + + Sbjct: 165 VMSVRDIA---ISKRHP--YMFSASEDKLVKCWDLERNTAIRDFHGHLSGVHTVDVHPSL 219 Query: 475 DIISSS 492 DII+++ Sbjct: 220 DIIATA 225 Score = 35.8 bits (81), Expect = 0.066 Identities = 20/72 (27%), Positives = 36/72 (50%) Frame = +1 Query: 247 PEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTM 426 P+ + LSK + GH+ +V + P + + +G DT + +W+L G++ T+ Sbjct: 106 PQWHAPWKLSKVINGHTGWVRCVCVDPVDNEW----FATGSNDTTIKIWDLAAGKLKITL 161 Query: 427 KGHTSQVTGLAI 462 GH V +AI Sbjct: 162 IGHVMSVRDIAI 173 Score = 31.2 bits (69), Expect = 1.6 Identities = 36/129 (27%), Positives = 55/129 (42%), Gaps = 2/129 (1%) Frame = +1 Query: 118 MAAYHLSAQLHGHEDDVRGICICG-DVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGH 294 +AA L L GH VR I I + ++S DK V+ W + +R + + GH Sbjct: 152 LAAGKLKITLIGHVMSVRDIAISKRHPYMFSASEDKLVKCW----DLERNTAI-RDFHGH 206 Query: 295 SSFVGPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGL-AIDDN 471 S V + P D I + G D V LW++ + + GH S + + + + Sbjct: 207 LSGVHTVDVHPSLD-----IIATAGRDAVVRLWDIRSRSEIMVLPGHKSPINKVKCLPVD 261 Query: 472 GDIISSSMD 498 IIS S D Sbjct: 262 PQIISCSGD 270
>PRP46_CANGA (Q6FJZ9) Pre-mRNA-splicing factor PRP46 (Pre-mRNA-processing| protein 46) Length = 427 Score = 40.0 bits (92), Expect = 0.004 Identities = 36/123 (29%), Positives = 50/123 (40%), Gaps = 2/123 (1%) Frame = +1 Query: 121 AAYHLSAQLHGHEDDVRGICI--CGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGH 294 A +HL+ +HGH VR I + + AT S DKT++ W K L TL H Sbjct: 103 APWHLTRVIHGHHGWVRCIAMDKVDNEWFATGSNDKTIKIWNLASGK-----LKVTLKAH 157 Query: 295 SSFVGPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNG 474 V + S+R P + S D V W+L GH S V + I Sbjct: 158 DMTVRDLA---ISNRHP--YMFSVSEDKTVKCWDLEKNTAIRNYHGHLSGVHTVDIHPTV 212 Query: 475 DII 483 D++ Sbjct: 213 DVV 215 Score = 34.7 bits (78), Expect = 0.15 Identities = 24/105 (22%), Positives = 45/105 (42%), Gaps = 11/105 (10%) Frame = +1 Query: 187 GDVGVATSSR-----------DKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPS 333 GDVG+ + + ++ + Q P + L++ + GH +V + Sbjct: 68 GDVGLVLNKKFADEQGHESVIERHDKLLNQTPRWHAPWHLTRVIHGHHGWVRCIAM---- 123 Query: 334 DRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDD 468 D+ +G D + +WNL +G++ T+K H V LAI + Sbjct: 124 DKVDNEWFATGSNDKTIKIWNLASGKLKVTLKAHDMTVRDLAISN 168
>Y163_SYNY3 (Q55563) Hypothetical WD-repeat protein sll0163| Length = 1693 Score = 40.0 bits (92), Expect = 0.004 Identities = 31/118 (26%), Positives = 47/118 (39%), Gaps = 2/118 (1%) Frame = +1 Query: 151 GHEDDVRGICICGD-VGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAP 327 GH VR D + T S D T R W + L GH ++V +W+P Sbjct: 1176 GHTSWVRNAQFSPDGQWIVTCSADGTARLWDLSSQ------CFAVLKGHQNWVNNALWSP 1229 Query: 328 PSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAID-DNGDIISSSMD 498 I++ D +W+ H G+ GT++GH + G D I++ S D Sbjct: 1230 DGQH-----IITSSSDGTARVWSRH-GKCLGTLRGHDHNIHGARFSLDGQKIVTYSTD 1281 Score = 38.1 bits (87), Expect = 0.013 Identities = 29/101 (28%), Positives = 43/101 (42%), Gaps = 1/101 (0%) Frame = +1 Query: 199 VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDT 378 +AT S D T R W R L GH VG + W+P +V+ D Sbjct: 1562 IATVSADHTARLWD------RSGKTVAVLYGHQGLVGTVDWSPDGQ-----MLVTASNDG 1610 Query: 379 QVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGD-IISSSMD 498 LW+L +G T++GH + V +G +++SS D Sbjct: 1611 TARLWDL-SGRELLTLEGHGNWVRSAEFSPDGRWVLTSSAD 1650 Score = 36.6 bits (83), Expect = 0.039 Identities = 30/100 (30%), Positives = 41/100 (41%), Gaps = 2/100 (2%) Frame = +1 Query: 205 TSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGA-IVSGGMDTQ 381 T SRDKT R WT E L H W P+G IV+G D Sbjct: 1359 TVSRDKTARLWTTEGE------CVAVLADHQG------WVREGQFSPDGQWIVTGSADKT 1406 Query: 382 VLLWNLHTGEVAGTMKGHTSQVTGLAID-DNGDIISSSMD 498 LWN+ G+ ++GH V + D+ I+++S D Sbjct: 1407 AQLWNV-LGKKLTVLRGHQDAVLNVRFSPDSQYIVTASKD 1445
>KTNB1_CHICK (Q5ZIU8) Katanin p80 WD40-containing subunit B1 (Katanin p80| subunit B1) (p80 katanin) Length = 657 Score = 40.0 bits (92), Expect = 0.004 Identities = 31/124 (25%), Positives = 54/124 (43%), Gaps = 2/124 (1%) Frame = +1 Query: 133 LSAQLHGHEDDVRGICICG-DVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVG 309 L +L GH + + I + + S+ ++R W K + +TL+GH + + Sbjct: 54 LRHELTGHTTPIESLQISAKEELIVAGSQSGSIRVWDLEAAK-----ILRTLLGHKANIC 108 Query: 310 PMVWAPPSDRFPEGAIV-SGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIIS 486 + D P G+ V SG +DT + LW++ K HT V L +G ++ Sbjct: 109 SL------DFHPYGSFVASGSLDTDIKLWDVRRKGCIFKYKSHTQAVRCLRFSPDGKWLA 162 Query: 487 SSMD 498 S+ D Sbjct: 163 SAAD 166
>GBB4_RAT (O35353) Guanine nucleotide-binding protein beta subunit 4| (Transducin beta chain 4) Length = 339 Score = 39.7 bits (91), Expect = 0.005 Identities = 30/122 (24%), Positives = 48/122 (39%) Frame = +1 Query: 133 LSAQLHGHEDDVRGICICGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGP 312 +S +L GH + D + TSS D T W ++ + T GHS V Sbjct: 134 VSRELPGHTGYLSCCRFLDDGQIITSSGDTTCALWDIETGQQ-----TTTFTGHSGDVMS 188 Query: 313 MVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSS 492 + +P F VSG D LW++ G + GH S + ++ +G ++ Sbjct: 189 LSLSPDLKTF-----VSGACDASSKLWDIRDGMCRQSFTGHISDINAVSFFPSGYAFATG 243 Query: 493 MD 498 D Sbjct: 244 SD 245
>GBB4_MOUSE (P29387) Guanine nucleotide-binding protein beta subunit 4| (Transducin beta chain 4) Length = 339 Score = 39.7 bits (91), Expect = 0.005 Identities = 30/122 (24%), Positives = 48/122 (39%) Frame = +1 Query: 133 LSAQLHGHEDDVRGICICGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGP 312 +S +L GH + D + TSS D T W ++ + T GHS V Sbjct: 134 VSRELPGHTGYLSCCRFLDDGQIITSSGDTTCALWDIETGQQ-----TTTFTGHSGDVMS 188 Query: 313 MVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSS 492 + +P F VSG D LW++ G + GH S + ++ +G ++ Sbjct: 189 LSLSPDLKTF-----VSGACDASSKLWDIRDGMCRQSFTGHISDINAVSFFPSGYAFATG 243 Query: 493 MD 498 D Sbjct: 244 SD 245
>HIRA_CHICK (P79987) HIRA protein (TUP1-like enhancer of split protein 1)| (CHIRA) Length = 1018 Score = 39.7 bits (91), Expect = 0.005 Identities = 32/122 (26%), Positives = 50/122 (40%), Gaps = 20/122 (16%) Frame = +1 Query: 193 VGVATSSRDKTVRFWTQHPEKKREYVLSKTLVG------------------HSSFVGPMV 318 V +A+ DK + W K+ Y+ T+ G HS V + Sbjct: 83 VYLASGGDDKLIMVW-----KRAAYIGPSTVFGSSSKLTNVEQWRCSILRSHSGDVMDVA 137 Query: 319 WAPPSDRFPEGAIVSGGMDTQVLLWN--LHTGEVAGTMKGHTSQVTGLAIDDNGDIISSS 492 W+P + + S +D V++WN + E+ T+KGH+ V GL D G I+S Sbjct: 138 WSPH-----DAWLASCSVDNTVVIWNAAVKFPEILATLKGHSGLVKGLTWDPVGKYIASQ 192 Query: 493 MD 498 D Sbjct: 193 AD 194
>PRL2_ARATH (Q39190) PP1/PP2A phosphatases pleiotropic regulator PRL2| Length = 479 Score = 39.7 bits (91), Expect = 0.005 Identities = 23/84 (27%), Positives = 41/84 (48%) Frame = +1 Query: 247 PEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTM 426 PE + + L GH +V + + P ++ F +G D + +W++ TG + T+ Sbjct: 154 PEWHAPWKNYRVLQGHLGWVRSVAFDPSNEWF-----CTGSADRTIKIWDVATGVLKLTL 208 Query: 427 KGHTSQVTGLAIDDNGDIISSSMD 498 GH QV GLA+ + + S+ D Sbjct: 209 TGHIGQVRGLAVSNRHTYMFSAGD 232 Score = 36.6 bits (83), Expect = 0.039 Identities = 33/114 (28%), Positives = 48/114 (42%), Gaps = 1/114 (0%) Frame = +1 Query: 145 LHGHEDDVRGICIC-GDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVW 321 L GH VR + + T S D+T++ W VL TL GH +G + Sbjct: 166 LQGHLGWVRSVAFDPSNEWFCTGSADRTIKIWDVATG-----VLKLTLTGH---IGQVRG 217 Query: 322 APPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDII 483 S+R + S G D QV W+L +V + GH V LA+ D++ Sbjct: 218 LAVSNRHTY--MFSAGDDKQVKCWDLEQNKVIRSYHGHLHGVYCLALHPTLDVV 269
>GBB1_DROME (P26308) Guanine nucleotide-binding protein beta subunit 1| Length = 340 Score = 39.7 bits (91), Expect = 0.005 Identities = 30/122 (24%), Positives = 46/122 (37%) Frame = +1 Query: 133 LSAQLHGHEDDVRGICICGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGP 312 +S +L GH + D + TSS D + W + + +GH+ V Sbjct: 135 VSRELPGHGGYLSCCRFLDDNQIVTSSGDMSCGLWDIETGLQ-----VTSFLGHTGDVMA 189 Query: 313 MVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSS 492 + AP F VSG D LW++ G T GH S + + NG ++ Sbjct: 190 LSLAPQCKTF-----VSGACDASAKLWDIREGVCKQTFPGHESDINAVTFFPNGQAFATG 244 Query: 493 MD 498 D Sbjct: 245 SD 246 Score = 30.0 bits (66), Expect = 3.6 Identities = 27/115 (23%), Positives = 51/115 (44%), Gaps = 2/115 (1%) Frame = +1 Query: 151 GHEDDVRGICICGD-VGVATSSRDKTVRFWTQHPEKKRE-YVLSKTLVGHSSFVGPMVWA 324 GHE D+ + + AT S D T R + +++ Y + G +S V Sbjct: 224 GHESDINAVTFFPNGQAFATGSDDATCRLFDIRADQELAMYSHDNIICGITS-----VAF 278 Query: 325 PPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISS 489 S R +++G D +W+ E +G + GH ++V+ L + +NG +++ Sbjct: 279 SKSGRL----LLAGYDDFNCNVWDTMKAERSGILAGHDNRVSCLGVTENGMAVAT 329
>GBB5_RAT (P62882) Guanine nucleotide-binding protein beta subunit 5| (Transducin beta chain 5) (Gbeta5) Length = 353 Score = 39.7 bits (91), Expect = 0.005 Identities = 26/103 (25%), Positives = 45/103 (43%) Frame = +1 Query: 190 DVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGG 369 D+ + T+S D T W + L ++ GH + V + AP VSGG Sbjct: 165 DMQILTASGDGTCALWDVESGQ-----LLQSFHGHGADVLCLDLAPSETG---NTFVSGG 216 Query: 370 MDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSSMD 498 D + ++W++ +G+ + H S V + +GD +S D Sbjct: 217 CDKKAMVWDMRSGQCVQAFETHESDVNSVRYYPSGDAFASGSD 259
>GBB5_MOUSE (P62881) Guanine nucleotide-binding protein beta subunit 5| (Transducin beta chain 5) (Gbeta5) Length = 395 Score = 39.7 bits (91), Expect = 0.005 Identities = 26/103 (25%), Positives = 45/103 (43%) Frame = +1 Query: 190 DVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGG 369 D+ + T+S D T W + L ++ GH + V + AP VSGG Sbjct: 207 DMQILTASGDGTCALWDVESGQ-----LLQSFHGHGADVLCLDLAPSETG---NTFVSGG 258 Query: 370 MDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSSMD 498 D + ++W++ +G+ + H S V + +GD +S D Sbjct: 259 CDKKAMVWDMRSGQCVQAFETHESDVNSVRYYPSGDAFASGSD 301
>GBB5_HUMAN (O14775) Guanine nucleotide-binding protein beta subunit 5| (Transducin beta chain 5) (Gbeta5) Length = 395 Score = 39.3 bits (90), Expect = 0.006 Identities = 25/103 (24%), Positives = 45/103 (43%) Frame = +1 Query: 190 DVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGG 369 D+ + T+S D T W + L ++ GH + V + AP VSGG Sbjct: 207 DMQILTASGDGTCALWDVESGQ-----LLQSFHGHGADVLCLDLAPSETG---NTFVSGG 258 Query: 370 MDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSSMD 498 D + ++W++ +G+ + H S + + +GD +S D Sbjct: 259 CDKKAMVWDMRSGQCVQAFETHESDINSVRYYPSGDAFASGSD 301
>WDR31_MOUSE (Q9JHB4) WD-repeat protein 31 (Spermatid WD-repeat protein) (spWD)| Length = 367 Score = 39.3 bits (90), Expect = 0.006 Identities = 34/122 (27%), Positives = 55/122 (45%), Gaps = 6/122 (4%) Frame = +1 Query: 151 GHEDDVRGI-CICGDVGVATSSRDKTVRFW----TQHPEKKREYVLSKTLVGHSSFVGPM 315 GHE ++ I CI ++SRDKTV W + HP ++ L GH+ V + Sbjct: 101 GHEREITKIACIPKANQFFSASRDKTVLMWDLQGSSHPRQQ--------LSGHAMVVTGL 152 Query: 316 VWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLA-IDDNGDIISSS 492 +P S + + +G D +LLW++ TG+ + VT L + I+ +S Sbjct: 153 AVSPDSSQ-----LCTGSRDNSLLLWDVGTGQCVERASVSRNLVTHLCWVPSEPYIVQTS 207 Query: 493 MD 498 D Sbjct: 208 ED 209 Score = 28.9 bits (63), Expect = 8.1 Identities = 15/48 (31%), Positives = 23/48 (47%), Gaps = 1/48 (2%) Frame = +1 Query: 358 VSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLA-IDDNGDIISSSMD 498 +SGG D + +N TG + GH ++T +A I S+S D Sbjct: 77 ISGGKDKTAVAYNWKTGRMVKRFTGHEREITKIACIPKANQFFSASRD 124
>TEP1_MOUSE (P97499) Telomerase protein component 1 (Telomerase-associated| protein 1) (Telomerase protein 1) (p240) (p80 homolog) Length = 2629 Score = 39.3 bits (90), Expect = 0.006 Identities = 34/122 (27%), Positives = 52/122 (42%), Gaps = 2/122 (1%) Frame = +1 Query: 139 AQLHGHEDDVRGICICGDVGV-ATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPM 315 A+L GHE V D G+ AT+ RD+ + W + L+ H+ Sbjct: 2063 AELRGHEGPVCCCSFSPDGGILATAGRDRNLLCWDMK-------IAQAPLLIHTFSSCHR 2115 Query: 316 VWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTG-LAIDDNGDIISSS 492 W + +VS D V LWN G+ G GH S V+ +A++++ I+S S Sbjct: 2116 DWITGCAWTKDNILVSCSSDGSVGLWNPEAGQQLGQFSGHQSAVSAVVAVEEH--IVSVS 2173 Query: 493 MD 498 D Sbjct: 2174 RD 2175
>GBB5_TAMST (Q80ZD0) Guanine nucleotide-binding protein beta subunit 5| (Transducin beta chain 5) (Gbeta5) Length = 353 Score = 39.3 bits (90), Expect = 0.006 Identities = 25/103 (24%), Positives = 45/103 (43%) Frame = +1 Query: 190 DVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGG 369 D+ + T+S D T W + L ++ GH + V + AP VSGG Sbjct: 165 DMQILTASGDGTCALWDVESGQ-----LLQSFHGHGADVLCLDLAPSETG---NTFVSGG 216 Query: 370 MDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSSMD 498 D + ++W++ +G+ + H S + + +GD +S D Sbjct: 217 CDKKAMVWDMRSGQCVQAFETHESDINSVRYYPSGDAFASGSD 259
>GBB5_RABIT (Q6PNB6) Guanine nucleotide-binding protein beta subunit 5| (Transducin beta chain 5) (Gbeta5) Length = 353 Score = 39.3 bits (90), Expect = 0.006 Identities = 25/103 (24%), Positives = 45/103 (43%) Frame = +1 Query: 190 DVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGG 369 D+ + T+S D T W + L ++ GH + V + AP VSGG Sbjct: 165 DMQILTASGDGTCALWDVESGQ-----LLQSFHGHGADVLCLDLAPSETG---NTFVSGG 216 Query: 370 MDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSSMD 498 D + ++W++ +G+ + H S + + +GD +S D Sbjct: 217 CDKKAMVWDMRSGQCVQAFETHESDINSVRYYPSGDAFASGSD 259
>GBB5_PONPY (Q5RDY7) Guanine nucleotide-binding protein beta subunit 5| (Transducin beta chain 5) (Gbeta5) Length = 353 Score = 39.3 bits (90), Expect = 0.006 Identities = 25/103 (24%), Positives = 45/103 (43%) Frame = +1 Query: 190 DVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGG 369 D+ + T+S D T W + L ++ GH + V + AP VSGG Sbjct: 165 DMQILTASGDGTCALWDVESGQ-----LLQSFHGHGADVLCLDLAPSETG---NTFVSGG 216 Query: 370 MDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSSMD 498 D + ++W++ +G+ + H S + + +GD +S D Sbjct: 217 CDKKAMVWDMRSGQCVQAFETHESDINSVRYYPSGDAFASGSD 259
>PRP46_SCHPO (O13615) Pre-mRNA-splicing factor prp46 (Pre-mRNA-processing| protein 5) (Complexed with cdc5 protein 1) Length = 473 Score = 39.3 bits (90), Expect = 0.006 Identities = 34/119 (28%), Positives = 52/119 (43%), Gaps = 2/119 (1%) Frame = +1 Query: 148 HGHEDDVRGICICGDVGV-ATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWA 324 HGH V + + + V T+ RD R W ++ +VLS GH S V + Sbjct: 244 HGHLSGVYALKLHPTLDVLVTAGRDAVARVWDMRT-RQNVHVLS----GHKSTVASLA-- 296 Query: 325 PPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAI-DDNGDIISSSMD 498 F + +V+G MD+ + LW+L G+ T+ H V L++ D S S D Sbjct: 297 --VQEF-DPQVVTGSMDSTIRLWDLAAGKTLTTLTHHKKTVRALSLHPDEFTFASGSSD 352 Score = 38.9 bits (89), Expect = 0.008 Identities = 35/122 (28%), Positives = 53/122 (43%), Gaps = 1/122 (0%) Frame = +1 Query: 121 AAYHLSAQLHGHEDDVRGICI-CGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHS 297 A + L + GH VR + + G+ T + D+T++ W VL TL GH Sbjct: 151 APWTLMRVISGHLGWVRCVDVEPGNQWFCTGAGDRTIKIWDL-----ASGVLKLTLTGHI 205 Query: 298 SFVGPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGD 477 + V + +P R P + S G D V W+L T +V GH S V L + D Sbjct: 206 ATVRGLAVSP---RHPY--LFSCGEDKMVKCWDLETNKVIRHYHGHLSGVYALKLHPTLD 260 Query: 478 II 483 ++ Sbjct: 261 VL 262 Score = 33.9 bits (76), Expect = 0.25 Identities = 21/72 (29%), Positives = 35/72 (48%) Frame = +1 Query: 247 PEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTM 426 PE + L + + GH +V + P + F GA D + +W+L +G + T+ Sbjct: 147 PEWHAPWTLMRVISGHLGWVRCVDVEPGNQWFCTGA-----GDRTIKIWDLASGVLKLTL 201 Query: 427 KGHTSQVTGLAI 462 GH + V GLA+ Sbjct: 202 TGHIATVRGLAV 213
>PWP2_SCHPO (Q9C1X1) Periodic tryptophan protein 2 homolog| Length = 854 Score = 39.3 bits (90), Expect = 0.006 Identities = 29/115 (25%), Positives = 54/115 (46%), Gaps = 3/115 (2%) Frame = +1 Query: 154 HEDDVRGICIC--GDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAP 327 H V G+C G+V + +SS D +VR W Y +T S + Sbjct: 380 HTSAVSGLCFSKRGNV-LFSSSLDGSVRAWDLI-----RYRNFRTFTAPSRVQFSCIAVD 433 Query: 328 PSDRFPEGAIVSGGMDT-QVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISS 489 PS + +G D+ ++ +W++ TG++ T+ GH V+ L+ + +G +++S Sbjct: 434 PSGEI----VCAGSQDSFEIFMWSVQTGQLLETLAGHEGPVSSLSFNSSGSLLAS 484 Score = 37.0 bits (84), Expect = 0.030 Identities = 17/49 (34%), Positives = 31/49 (63%), Gaps = 1/49 (2%) Frame = +1 Query: 355 IVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDII-SSSMD 498 I++G D ++ +W++++G T HTS V+GL G+++ SSS+D Sbjct: 354 IITGADDGKIKVWDMNSGFCIVTFTQHTSAVSGLCFSKRGNVLFSSSLD 402 Score = 31.6 bits (70), Expect = 1.2 Identities = 33/125 (26%), Positives = 47/125 (37%), Gaps = 7/125 (5%) Frame = +1 Query: 145 LHGHEDDVRGICICGDVGV-ATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVW 321 L GHE V + + A+ S DKTVR W + S V P+ Sbjct: 463 LAGHEGPVSSLSFNSSGSLLASGSWDKTVRIWD--------------IFSRSGIVEPL-- 506 Query: 322 APPSDRF-----PEGAIVS-GGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDII 483 PSD P+G V +D Q+ WN+ G+ + G G DD Sbjct: 507 PIPSDVLSLAFHPDGKEVCVASLDGQLTFWNVQEGKQTSLIDGRKDLSGGRRFDDARTAE 566 Query: 484 SSSMD 498 +SS++ Sbjct: 567 NSSLN 571
>PRL1_ARATH (Q42384) PP1/PP2A phosphatases pleiotropic regulator PRL1| Length = 486 Score = 38.9 bits (89), Expect = 0.008 Identities = 22/84 (26%), Positives = 41/84 (48%) Frame = +1 Query: 247 PEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTM 426 PE + + + GH +V + + P ++ F +G D + +W++ TG + T+ Sbjct: 160 PEWHAPWKNYRVIQGHLGWVRSVAFDPSNEWF-----CTGSADRTIKIWDVATGVLKLTL 214 Query: 427 KGHTSQVTGLAIDDNGDIISSSMD 498 GH QV GLA+ + + S+ D Sbjct: 215 TGHIEQVRGLAVSNRHTYMFSAGD 238 Score = 35.4 bits (80), Expect = 0.086 Identities = 33/114 (28%), Positives = 48/114 (42%), Gaps = 1/114 (0%) Frame = +1 Query: 145 LHGHEDDVRGICIC-GDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVW 321 + GH VR + + T S D+T++ W VL TL GH V + Sbjct: 172 IQGHLGWVRSVAFDPSNEWFCTGSADRTIKIWDVATG-----VLKLTLTGHIEQVRGLA- 225 Query: 322 APPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDII 483 S+R + S G D QV W+L +V + GH S V LA+ D++ Sbjct: 226 --VSNRHTY--MFSAGDDKQVKCWDLEQNKVIRSYHGHLSGVYCLALHPTLDVL 275 Score = 33.9 bits (76), Expect = 0.25 Identities = 26/106 (24%), Positives = 46/106 (43%), Gaps = 1/106 (0%) Frame = +1 Query: 133 LSAQLHGHEDDVRGICICG-DVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVG 309 L L GH + VRG+ + + ++ DK V+ W K + ++ GH S V Sbjct: 210 LKLTLTGHIEQVRGLAVSNRHTYMFSAGDDKQVKCWDLEQNK-----VIRSYHGHLSGVY 264 Query: 310 PMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQV 447 + P D +++GG D+ +W++ T + GH + V Sbjct: 265 CLALHPTLD-----VLLTGGRDSVCRVWDIRTKMQIFALSGHDNTV 305
>PRP4_HUMAN (O43172) U4/U6 small nuclear ribonucleoprotein Prp4 (U4/U6 snRNP 60| kDa protein) (WD splicing factor Prp4) (hPrp4) Length = 522 Score = 38.9 bits (89), Expect = 0.008 Identities = 30/116 (25%), Positives = 51/116 (43%), Gaps = 1/116 (0%) Frame = +1 Query: 145 LHGHEDDVRGICICGD-VGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVW 321 L GH ++ GI + +AT S D T + W ++R V T+ H + V + + Sbjct: 403 LEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDL---RQRRCVY--TIPAHQNLVTGVKF 457 Query: 322 APPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISS 489 P F +++G D +W T+ GH +V GL I +G +I++ Sbjct: 458 EPIHGNF----LLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLIAT 509 Score = 33.5 bits (75), Expect = 0.33 Identities = 23/77 (29%), Positives = 39/77 (50%), Gaps = 3/77 (3%) Frame = +1 Query: 271 LSKTLVGHSSFVGPMVWAPPS--DRFPEGA-IVSGGMDTQVLLWNLHTGEVAGTMKGHTS 441 L TL GH++ VG +V+ P S P+ + S D V LW+L + E ++GHT Sbjct: 265 LLHTLRGHNTNVGAIVFHPKSTVSLDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHTV 324 Query: 442 QVTGLAIDDNGDIISSS 492 +V + +G + ++ Sbjct: 325 RVARVMWHPSGRFLGTT 341 Score = 32.3 bits (72), Expect = 0.73 Identities = 23/93 (24%), Positives = 44/93 (47%), Gaps = 1/93 (1%) Frame = +1 Query: 199 VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIV-SGGMD 375 + T+ D++ R W + E +L + GHS V + + +G++ +GG+D Sbjct: 338 LGTTCYDRSWRLWDLEAQ---EEILHQE--GHSMGVYDIAF------HQDGSLAGTGGLD 386 Query: 376 TQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNG 474 +W+L TG ++GH ++ G+ NG Sbjct: 387 AFGRVWDLRTGRCIMFLEGHLKEIYGINFSPNG 419 Score = 31.2 bits (69), Expect = 1.6 Identities = 24/97 (24%), Positives = 44/97 (45%) Frame = +1 Query: 190 DVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGG 369 DV +A+ + D +V+ W+ ++ + GH+ V ++W P S RF + + Sbjct: 293 DVNLASCAADGSVKLWSLDSDEP-----VADIEGHTVRVARVMWHP-SGRF----LGTTC 342 Query: 370 MDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDI 480 D LW+L E +GH+ V +A +G + Sbjct: 343 YDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSL 379
>WDR12_MOUSE (Q9JJA4) WD-repeat protein 12 (YTM1 homolog)| Length = 423 Score = 38.9 bits (89), Expect = 0.008 Identities = 26/96 (27%), Positives = 42/96 (43%), Gaps = 4/96 (4%) Frame = +1 Query: 199 VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDT 378 + + S DKT R W+ + T+VGH+ V + W +++ MD Sbjct: 114 ILSGSYDKTSRIWSLEGKS------IMTIVGHTDVVKDVAWVKKDSL--SCLLLTASMDQ 165 Query: 379 QVLLW--NLHTGEVAGT--MKGHTSQVTGLAIDDNG 474 VLLW N+ +V +GH V +A+D +G Sbjct: 166 TVLLWEWNVEKNKVKALHCCRGHAGSVDAIAVDSSG 201 Score = 31.6 bits (70), Expect = 1.2 Identities = 30/123 (24%), Positives = 52/123 (42%), Gaps = 5/123 (4%) Frame = +1 Query: 145 LHGHEDDVRGICICGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWA 324 L GH + + + + ++S D T+R W L TL G+ F + ++ Sbjct: 253 LSGHTEAISSVLWSDAEEICSASWDHTIRVWDVESGG-----LKSTLTGNKVF-NCISYS 306 Query: 325 PPSDRFPEGAIVSGGMDTQVLLWNLHTGE---VAGTMKGHTSQVTGLAIDDNGD--IISS 489 P R + SG D + LW+ T + V+ ++ HT VT + + +IS Sbjct: 307 PLCKR-----LASGSTDRHIRLWDPRTKDGSLVSLSLTSHTGWVTSVKWSPTHEQQLISG 361 Query: 490 SMD 498 S+D Sbjct: 362 SLD 364
>BRWD1_MOUSE (Q921C3) Bromodomain and WD-repeat domain-containing protein 1| (WD-repeat protein 9) Length = 2304 Score = 38.9 bits (89), Expect = 0.008 Identities = 24/86 (27%), Positives = 38/86 (44%) Frame = +1 Query: 199 VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDT 378 + T S D V+ W+ H + L TL GHS+ + M + + I +G D Sbjct: 201 IFTGSDDCLVKIWSTHNGR-----LLSTLRGHSAEISDM-----AVNYENTLIAAGSCDK 250 Query: 379 QVLLWNLHTGEVAGTMKGHTSQVTGL 456 + +W L T ++GHT +T L Sbjct: 251 VIRVWCLRTCAPVAVLQGHTGSITSL 276 Score = 38.1 bits (87), Expect = 0.013 Identities = 20/87 (22%), Positives = 46/87 (52%), Gaps = 1/87 (1%) Frame = +1 Query: 232 FWTQHPEKKREYV-LSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTG 408 F T P +++ + + ++GH S V + + R I +G D V +W+ H G Sbjct: 164 FSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHR-----IFTGSDDCLVKIWSTHNG 218 Query: 409 EVAGTMKGHTSQVTGLAIDDNGDIISS 489 + T++GH+++++ +A++ +I++ Sbjct: 219 RLLSTLRGHSAEISDMAVNYENTLIAA 245 Score = 34.7 bits (78), Expect = 0.15 Identities = 29/111 (26%), Positives = 50/111 (45%), Gaps = 8/111 (7%) Frame = +1 Query: 139 AQLHGHEDDVRGICICGDVG-VATSSRDKTVRFWTQHPEKKREYVL--SKTLVGHSS--- 300 A+L H D V I C + + SRD T R W + R +L S + G +S Sbjct: 362 AELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQLEWRSILLDMSARISGDTSSEE 421 Query: 301 --FVGPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQV 447 F+ P V ++ + +V+ D + +W+ +TG++ + GH +V Sbjct: 422 ERFMKPKVTMIAWNQ-DDSTVVTAVNDHVLKVWSSYTGQLLHNLLGHADEV 471
>PRP4_PONPY (Q5NVD0) U4/U6 small nuclear ribonucleoprotein Prp4 (U4/U6 snRNP 60| kDa protein) (WD splicing factor Prp4) Length = 521 Score = 38.9 bits (89), Expect = 0.008 Identities = 30/116 (25%), Positives = 51/116 (43%), Gaps = 1/116 (0%) Frame = +1 Query: 145 LHGHEDDVRGICICGD-VGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVW 321 L GH ++ GI + +AT S D T + W ++R V T+ H + V + + Sbjct: 402 LEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDL---RQRRCVY--TIPAHQNLVTGVKF 456 Query: 322 APPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISS 489 P F +++G D +W T+ GH +V GL I +G +I++ Sbjct: 457 EPIHGNF----LLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLIAT 508 Score = 33.1 bits (74), Expect = 0.43 Identities = 22/77 (28%), Positives = 38/77 (49%), Gaps = 3/77 (3%) Frame = +1 Query: 271 LSKTLVGHSSFVGPMVWAPPSDRFPEGA---IVSGGMDTQVLLWNLHTGEVAGTMKGHTS 441 L TL GH++ VG +V+ P S + + S D V LW+L + E ++GHT Sbjct: 264 LLHTLRGHNTNVGAIVFHPKSTVSLDQKDVNLASCAADGSVKLWSLDSDEPVADIEGHTV 323 Query: 442 QVTGLAIDDNGDIISSS 492 +V + +G + ++ Sbjct: 324 RVARVMWHPSGRFLGTT 340 Score = 32.3 bits (72), Expect = 0.73 Identities = 23/93 (24%), Positives = 44/93 (47%), Gaps = 1/93 (1%) Frame = +1 Query: 199 VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIV-SGGMD 375 + T+ D++ R W + E +L + GHS V + + +G++ +GG+D Sbjct: 337 LGTTCYDRSWRLWDLEAQ---EEILHQE--GHSMGVYDIAF------HQDGSLAGTGGLD 385 Query: 376 TQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNG 474 +W+L TG ++GH ++ G+ NG Sbjct: 386 AFGRVWDLRTGRCIMFLEGHLKEIYGINFSPNG 418 Score = 31.2 bits (69), Expect = 1.6 Identities = 24/97 (24%), Positives = 44/97 (45%) Frame = +1 Query: 190 DVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGG 369 DV +A+ + D +V+ W+ ++ + GH+ V ++W P S RF + + Sbjct: 292 DVNLASCAADGSVKLWSLDSDEP-----VADIEGHTVRVARVMWHP-SGRF----LGTTC 341 Query: 370 MDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDI 480 D LW+L E +GH+ V +A +G + Sbjct: 342 YDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSL 378
>PF20_CHLRE (P93107) Flagellar WD-repeat protein PF20| Length = 606 Score = 38.9 bits (89), Expect = 0.008 Identities = 27/98 (27%), Positives = 41/98 (41%) Frame = +1 Query: 199 VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDT 378 VA+ S D TVR W K R L GH V + W P S ++ + D Sbjct: 425 VASGSLDHTVRLWDLPAGKCR-----MALRGHVDSVNDLAWQPFSS-----SLATASSDK 474 Query: 379 QVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSS 492 V +W+ G T GH + G++ + G ++S+ Sbjct: 475 TVSVWDARAGLCTQTYYGHQNSCNGVSFNILGTQLAST 512 Score = 35.0 bits (79), Expect = 0.11 Identities = 29/104 (27%), Positives = 43/104 (41%), Gaps = 1/104 (0%) Frame = +1 Query: 151 GHEDDVRGICIC-GDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAP 327 GH+D V G+ +A+ D V+ W EK+R T H +W+ Sbjct: 366 GHKDWVAGVDFHPAGTCLASGGGDSAVKIWDF--EKQR---CVTTFTDHKQ----AIWSV 416 Query: 328 PSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLA 459 E + SG +D V LW+L G+ ++GH V LA Sbjct: 417 RFHHLGE-VVASGSLDHTVRLWDLPAGKCRMALRGHVDSVNDLA 459 Score = 29.3 bits (64), Expect = 6.2 Identities = 23/98 (23%), Positives = 36/98 (36%), Gaps = 1/98 (1%) Frame = +1 Query: 199 VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGA-IVSGGMD 375 + T+S DKT + W L GH W D P G + SGG D Sbjct: 341 LVTASDDKTWKMWHMPGGD-----LIMCGEGHKD------WVAGVDFHPAGTCLASGGGD 389 Query: 376 TQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISS 489 + V +W+ T H + + G++++S Sbjct: 390 SAVKIWDFEKQRCVTTFTDHKQAIWSVRFHHLGEVVAS 427
>YRG5_CAEEL (Q09406) Hypothetical WD-repeat protein K06A1.5| Length = 464 Score = 38.9 bits (89), Expect = 0.008 Identities = 28/119 (23%), Positives = 49/119 (41%) Frame = +1 Query: 142 QLHGHEDDVRGICICGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVW 321 +L H+ +V + D AT+ D V+ W P K +S S +GP+ Sbjct: 170 KLSTHDGEVHDVEWMSDDTFATAGSDSKVQIWRVSPNKTDASKVSTL----SGCLGPVNR 225 Query: 322 APPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSSMD 498 + ++ D LWN+ + + T GHT +V+ + + ++IS S D Sbjct: 226 LDYDSQ--RHVCLASSNDKTCRLWNIDSQRLLSTFSGHTDKVSSARLFQSHNVISGSAD 282
>WD51A_HUMAN (Q8NBT0) WD-repeat protein 51A| Length = 407 Score = 38.9 bits (89), Expect = 0.008 Identities = 31/102 (30%), Positives = 51/102 (50%), Gaps = 2/102 (1%) Frame = +1 Query: 199 VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGA-IVSGGMD 375 + ++S DKTV+ W + RE V S H FV + D P G I + GMD Sbjct: 160 IVSASDDKTVKLWDK---SSRECVHS--YCEHGGFVTYV------DFHPSGTCIAAAGMD 208 Query: 376 TQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGD-IISSSMD 498 V +W++ T + + H++ V GL+ +G+ +I++S D Sbjct: 209 NTVKVWDVRTHRLLQHYQLHSAAVNGLSFHPSGNYLITASSD 250 Score = 32.7 bits (73), Expect = 0.56 Identities = 27/100 (27%), Positives = 42/100 (42%) Frame = +1 Query: 199 VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDT 378 +A+ SRDKTVR W P K E S H++ V + + F V+ D Sbjct: 76 LASGSRDKTVRIWV--PNVKGE---STVFRAHTATVRSVHFCSDGQSF-----VTASDDK 125 Query: 379 QVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSSMD 498 V +W H + ++ H + V +G +I S+ D Sbjct: 126 TVKVWATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASD 165
>STRN3_MOUSE (Q9ERG2) Striatin-3 (Cell-cycle autoantigen SG2NA) (S/G2 antigen)| Length = 796 Score = 38.9 bits (89), Expect = 0.008 Identities = 35/134 (26%), Positives = 56/134 (41%), Gaps = 16/134 (11%) Frame = +1 Query: 145 LHGHEDDVRGICICG-DVGVATSSRDKTVRFWTQH---PEKKREYVLSKTLVGHSSFVGP 312 L H D VR + + + T+S D T++ W P KK + + + + +GP Sbjct: 475 LRSHFDGVRALAFHPVEPVLVTASEDHTLKLWNLQKTVPAKKSASLDVEPIYTFRAHIGP 534 Query: 313 MVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEV-----------AGTMKGHTSQVTGLA 459 ++ S + SGG+D + WN+ + V AGT+ HT V GLA Sbjct: 535 VLSLAISSNGEQ--CFSGGIDATIQWWNMPSPNVDPYDTYESNVLAGTLVAHTDAVWGLA 592 Query: 460 IDD-NGDIISSSMD 498 ++S S D Sbjct: 593 YSGIKNQLLSCSAD 606 Score = 31.6 bits (70), Expect = 1.2 Identities = 16/44 (36%), Positives = 25/44 (56%), Gaps = 1/44 (2%) Frame = +1 Query: 373 DTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNG-DIISSSMDC 501 D + ++ TG++ +M H VT LA+D NG ++S S DC Sbjct: 701 DRHIKFFDNKTGKMIHSMVAHLDAVTSLAVDPNGIYLMSGSHDC 744
>MORG1_XENTR (Q5XGI5) Mitogen-activated protein kinase organizer 1 (MAPK| organizer 1) Length = 314 Score = 38.5 bits (88), Expect = 0.010 Identities = 24/95 (25%), Positives = 40/95 (42%) Frame = +1 Query: 205 TSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDTQV 384 T DKT++ W H + L KT GH V + + + S D V Sbjct: 42 TCGSDKTLKLWNPH-----KGTLLKTYSGHGYEV-----LDTAGSYDNSQMCSCSSDKTV 91 Query: 385 LLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISS 489 +LW++ G+V +GH +V + ++ +I S Sbjct: 92 ILWDVAQGQVVRKFRGHAGKVNCVQFNEEATVIMS 126
>MAK11_YEAST (P20484) Protein MAK11 (Maintenance of killer protein 11)| Length = 468 Score = 38.5 bits (88), Expect = 0.010 Identities = 25/110 (22%), Positives = 50/110 (45%), Gaps = 10/110 (9%) Frame = +1 Query: 199 VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGM-- 372 + + S D+ +R + +K++E TL+ H + + ++ P+ + A+ G Sbjct: 119 LVSGSNDEHIRIYDL--QKRKEL---GTLLSHQGSITALQFSHPASSSEDAAVSKGSKNS 173 Query: 373 --------DTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSSMD 498 D ++++W + E GT+KGHT++V + I I S D Sbjct: 174 KWLLSASEDHKIMVWRVKDWETVGTLKGHTARVNDVDIHPTNRIAISVSD 223
>TB1RB_XENLA (Q6GPC6) F-box-like/WD-repeat-containing protein TBL1XR1-B| (Transducin beta-like 1X-related homolog 1-B) (Nuclear receptor corepressor/HDAC3 complex subunit TBLR1-B) (TBL1-related protein 1-B) Length = 522 Score = 38.5 bits (88), Expect = 0.010 Identities = 26/100 (26%), Positives = 40/100 (40%) Frame = +1 Query: 199 VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDT 378 +AT S D R WT+ L+ TL H + + W + I+S G+D Sbjct: 248 LATGSYDGFARIWTKDGN------LASTLGQHKGPIFALKWNKKGN-----FILSAGVDK 296 Query: 379 QVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSSMD 498 ++W+ HTGE H++ + N S S D Sbjct: 297 TTIIWDAHTGEAKQQFPFHSAPALDVDWQSNNTFASCSTD 336 Score = 30.8 bits (68), Expect = 2.1 Identities = 21/71 (29%), Positives = 30/71 (42%), Gaps = 3/71 (4%) Frame = +1 Query: 283 LVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMK---GHTSQVTG 453 L GH S V W P SD + SG D+ +WNL +G+ + H + G Sbjct: 173 LRGHESEVFICAWNPVSD-----LLASGSGDSTARIWNLSENSTSGSTQLVLRHCIREGG 227 Query: 454 LAIDDNGDIIS 486 + N D+ S Sbjct: 228 QDVPSNKDVTS 238
>TBL1R_MOUSE (Q8BHJ5) F-box-like/WD-repeat protein TBL1XR1 (Transducin beta-like| 1X-related protein 1) (Nuclear receptor corepressor/HDAC3 complex subunit TBLR1) (TBL1-related protein 1) Length = 514 Score = 38.5 bits (88), Expect = 0.010 Identities = 26/100 (26%), Positives = 40/100 (40%) Frame = +1 Query: 199 VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDT 378 +AT S D R WT+ L+ TL H + + W + I+S G+D Sbjct: 240 LATGSYDGFARIWTKDGN------LASTLGQHKGPIFALKWNKKGN-----FILSAGVDK 288 Query: 379 QVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSSMD 498 ++W+ HTGE H++ + N S S D Sbjct: 289 TTIIWDAHTGEAKQQFPFHSAPALDVDWQSNNTFASCSTD 328 Score = 30.0 bits (66), Expect = 3.6 Identities = 21/71 (29%), Positives = 29/71 (40%), Gaps = 3/71 (4%) Frame = +1 Query: 283 LVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMK---GHTSQVTG 453 L GH S V W P SD + SG D+ +WNL +G + H + G Sbjct: 165 LRGHESEVFICAWNPVSD-----LLASGSGDSTARIWNLSENSTSGPTQLVLRHCIREGG 219 Query: 454 LAIDDNGDIIS 486 + N D+ S Sbjct: 220 QDVPSNKDVTS 230
>TBL1R_HUMAN (Q9BZK7) F-box-like/WD-repeat protein TBL1XR1 (Transducin beta-like| 1X-related protein 1) (Nuclear receptor corepressor/HDAC3 complex subunit TBLR1) (TBL1-related protein 1) Length = 514 Score = 38.5 bits (88), Expect = 0.010 Identities = 26/100 (26%), Positives = 40/100 (40%) Frame = +1 Query: 199 VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDT 378 +AT S D R WT+ L+ TL H + + W + I+S G+D Sbjct: 240 LATGSYDGFARIWTKDGN------LASTLGQHKGPIFALKWNKKGN-----FILSAGVDK 288 Query: 379 QVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSSMD 498 ++W+ HTGE H++ + N S S D Sbjct: 289 TTIIWDAHTGEAKQQFPFHSAPALDVDWQSNNTFASCSTD 328 Score = 30.8 bits (68), Expect = 2.1 Identities = 21/71 (29%), Positives = 30/71 (42%), Gaps = 3/71 (4%) Frame = +1 Query: 283 LVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMK---GHTSQVTG 453 L GH S V W P SD + SG D+ +WNL +G+ + H + G Sbjct: 165 LRGHESEVFICAWNPVSD-----LLASGSGDSTARIWNLSENSTSGSTQLVLRHCIREGG 219 Query: 454 LAIDDNGDIIS 486 + N D+ S Sbjct: 220 QDVPSNKDVTS 230
>GBB1_HOMAM (O45040) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 1 (Transducin beta chain 1) Length = 340 Score = 38.5 bits (88), Expect = 0.010 Identities = 29/122 (23%), Positives = 44/122 (36%) Frame = +1 Query: 133 LSAQLHGHEDDVRGICICGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGP 312 +S +L GH + D + TSS D T W ++ GH+ V Sbjct: 135 VSRELPGHTGYLSCCRFVDDNQIVTSSGDMTCALWDIETGQQ-----CTQFTGHTGDVMS 189 Query: 313 MVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSS 492 + +P F SG D LW++ G T GH S + + NG ++ Sbjct: 190 LSLSPNMRTF-----TSGACDASAKLWDIRDGMCRQTFPGHESDINAVTFFPNGHAFATG 244 Query: 493 MD 498 D Sbjct: 245 SD 246
>CWF17_SCHPO (O94620) Cell cycle control protein cwf17| Length = 340 Score = 38.5 bits (88), Expect = 0.010 Identities = 17/46 (36%), Positives = 27/46 (58%), Gaps = 1/46 (2%) Frame = +1 Query: 364 GGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAID-DNGDIISSSMD 498 GG+D + +W+L + +KGH +T LAI D ++S+SMD Sbjct: 195 GGIDGAIKIWDLRNNHCSHVLKGHKDIITSLAISKDGSSLLSNSMD 240 Score = 30.4 bits (67), Expect = 2.8 Identities = 18/41 (43%), Positives = 24/41 (58%), Gaps = 3/41 (7%) Frame = +1 Query: 343 PEGA-IVSGGMDTQVLLWNLHTGEVA--GTMKGHTSQVTGL 456 P G+ SGGMD Q+LLWN+ G+V G + G +T L Sbjct: 60 PSGSYFASGGMDRQILLWNVF-GDVKNYGVLNGCKGAITDL 99
>TBLX_MOUSE (Q9QXE7) F-box-like/WD-repeat protein TBL1X (Transducin beta-like| 1X protein) Length = 527 Score = 38.5 bits (88), Expect = 0.010 Identities = 26/100 (26%), Positives = 41/100 (41%) Frame = +1 Query: 199 VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDT 378 +AT S D R WT+ L+ TL H + + W + I+S G+D Sbjct: 253 LATGSYDGFARIWTEDGN------LASTLGQHKGPIFALKWNKKGNY-----ILSAGVDK 301 Query: 379 QVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSSMD 498 ++W+ HTGE H++ + +N S S D Sbjct: 302 TTIIWDAHTGEAKQQFPFHSAPALDVDWQNNTTFASCSTD 341 Score = 29.6 bits (65), Expect = 4.7 Identities = 21/71 (29%), Positives = 30/71 (42%), Gaps = 3/71 (4%) Frame = +1 Query: 283 LVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMK---GHTSQVTG 453 L GH S V W P SD + SG D+ +WNL+ G+ + H + G Sbjct: 178 LRGHESEVFICAWNPVSD-----LLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGG 232 Query: 454 LAIDDNGDIIS 486 + N D+ S Sbjct: 233 HDVPSNKDVTS 243
>BRWD1_HUMAN (Q9NSI6) Bromodomain and WD-repeat domain-containing protein 1| (WD-repeat protein 9) Length = 2320 Score = 38.5 bits (88), Expect = 0.010 Identities = 24/86 (27%), Positives = 38/86 (44%) Frame = +1 Query: 199 VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDT 378 + T S D V+ W+ H + L TL GHS+ + M + + I +G D Sbjct: 201 IFTGSDDCLVKIWSTHNGR-----LLSTLRGHSAEISDM-----AVNYENTMIAAGSCDK 250 Query: 379 QVLLWNLHTGEVAGTMKGHTSQVTGL 456 + +W L T ++GHT +T L Sbjct: 251 IIRVWCLRTCAPVAVLQGHTGSITSL 276 Score = 38.1 bits (87), Expect = 0.013 Identities = 23/91 (25%), Positives = 48/91 (52%), Gaps = 2/91 (2%) Frame = +1 Query: 232 FWTQHPEKKREYV-LSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTG 408 F T P +++ + + ++GH S V + + R I +G D V +W+ H G Sbjct: 164 FSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHR-----IFTGSDDCLVKIWSTHNG 218 Query: 409 EVAGTMKGHTSQVTGLAID-DNGDIISSSMD 498 + T++GH+++++ +A++ +N I + S D Sbjct: 219 RLLSTLRGHSAEISDMAVNYENTMIAAGSCD 249 Score = 33.9 bits (76), Expect = 0.25 Identities = 29/111 (26%), Positives = 48/111 (43%), Gaps = 8/111 (7%) Frame = +1 Query: 139 AQLHGHEDDVRGICICGDVG-VATSSRDKTVRFWTQHPEKKREYVLSKT--LVGHSS--- 300 A+L H D V I C + + SRD T R W + R +L + G S Sbjct: 362 AELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQLEWRSILLDMATRISGDLSSEE 421 Query: 301 --FVGPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQV 447 F+ P V ++ + +V+ D + +WN +TG++ + GH +V Sbjct: 422 ERFMKPKVTMIAWNQ-NDSIVVTAVNDHVLKVWNSYTGQLLHNLMGHADEV 471
>TB1RA_XENLA (Q7SZM9) F-box-like/WD-repeat-containing protein TBL1XR1-A| (Transducin beta-like 1X-related protein 1-A) (Nuclear receptor corepressor/HDAC3 complex subunit TBLR1-A) (TBL1-related protein 1-A) (xTBLR1) Length = 519 Score = 38.5 bits (88), Expect = 0.010 Identities = 26/100 (26%), Positives = 40/100 (40%) Frame = +1 Query: 199 VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDT 378 +AT S D R WT+ L+ TL H + + W + I+S G+D Sbjct: 245 LATGSYDGFARIWTKDGN------LASTLGQHKGPIFALKWNKKGN-----FILSAGVDK 293 Query: 379 QVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSSMD 498 ++W+ HTGE H++ + N S S D Sbjct: 294 TTIIWDAHTGEAKQQFPFHSAPALDVDWQSNNTFASCSTD 333 Score = 30.8 bits (68), Expect = 2.1 Identities = 21/71 (29%), Positives = 30/71 (42%), Gaps = 3/71 (4%) Frame = +1 Query: 283 LVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMK---GHTSQVTG 453 L GH S V W P SD + SG D+ +WNL +G+ + H + G Sbjct: 170 LRGHESEVFICAWNPVSD-----LLASGSGDSTARIWNLSENSTSGSTQLVLRHCIREGG 224 Query: 454 LAIDDNGDIIS 486 + N D+ S Sbjct: 225 QDVPSNKDVTS 235
>PWP2_MOUSE (Q8BU03) Periodic tryptophan protein 2 homolog| Length = 919 Score = 38.1 bits (87), Expect = 0.013 Identities = 26/83 (31%), Positives = 43/83 (51%), Gaps = 1/83 (1%) Frame = +1 Query: 253 KKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKG 432 + YVL + GH + + + ++P IV+GG D +V +WN +G T+ Sbjct: 361 QSESYVLKQQ--GHFNSMVALAYSPDGQY-----IVTGGDDGKVKVWNTLSGFCFVTLTE 413 Query: 433 HTSQVTGLAIDDNGD-IISSSMD 498 H+S VTG+ G I++SS+D Sbjct: 414 HSSGVTGVTFTTTGHVIVTSSLD 436 Score = 33.9 bits (76), Expect = 0.25 Identities = 32/117 (27%), Positives = 48/117 (41%), Gaps = 4/117 (3%) Frame = +1 Query: 154 HEDDVRGICIC--GDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAP 327 H V G+ G V + TSS D TVR + H Y +T V Sbjct: 414 HSSGVTGVTFTTTGHV-IVTSSLDGTVRAFDLH-----RYRNFRTFTSPRPTQFSCVAVD 467 Query: 328 PSDRFPEGAIVSGGMDT--QVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSS 492 S G IVS G ++ +W++ TG + + GH V+GL + I++S+ Sbjct: 468 SS-----GEIVSAGAQDSFEIFVWSMQTGRLLDVLSGHEGPVSGLCFNPMKSILASA 519 Score = 32.7 bits (73), Expect = 0.56 Identities = 28/110 (25%), Positives = 45/110 (40%), Gaps = 7/110 (6%) Frame = +1 Query: 145 LHGHEDDVRGICICGDVGV-ATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVW 321 L GHE V G+C + A++S DKTVR W + + L+ T Sbjct: 497 LSGHEGPVSGLCFNPMKSILASASWDKTVRLWDMFDSWRTKETLTLT------------- 543 Query: 322 APPSDRF-----PEGA-IVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTG 453 SD P+GA + +++Q+ W+ G+++G TG Sbjct: 544 ---SDALAVTFRPDGAELAVATLNSQITFWDPENAVQVGSIEGRHDLKTG 590
>GBB2_DROME (P29829) Guanine nucleotide-binding protein beta subunit 2| Length = 346 Score = 38.1 bits (87), Expect = 0.013 Identities = 28/116 (24%), Positives = 55/116 (47%), Gaps = 2/116 (1%) Frame = +1 Query: 151 GHEDDVRGICIC-GDVGVATSSRDKTVRFWTQHPEKK-REYVLSKTLVGHSSFVGPMVWA 324 GH+ DV +C G A+ S D+T R + +++ +Y + G +S Sbjct: 230 GHDMDVSSVCYHPSGFGFASCSEDQTARMYDLRADQQIAQYEPPQKNTGFTSCA-----L 284 Query: 325 PPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSS 492 S R+ ++ GG++ V W+ GT+ GH +++T +++ NG ++S+ Sbjct: 285 STSGRY----LMCGGIEGNVHSWDTMKQRHTGTLSGHENRITCISLCPNGMCLAST 336 Score = 32.3 bits (72), Expect = 0.73 Identities = 21/76 (27%), Positives = 36/76 (47%), Gaps = 2/76 (2%) Frame = +1 Query: 277 KTLVGHSSFVGPMVWAPPSDRF-PEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTG 453 K L+G+ F+ S RF +G +++G D ++ W+L G GH + G Sbjct: 143 KELMGYEGFLS-------SCRFLDDGHLITGSGDMKICHWDLEKGVKTMDFNGHAGDIAG 195 Query: 454 LAID-DNGDIISSSMD 498 L++ D I+ S+D Sbjct: 196 LSLSPDMKTYITGSVD 211
>HIRA_DROME (O17468) HIRA protein homolog (dHIRA)| Length = 1047 Score = 38.1 bits (87), Expect = 0.013 Identities = 31/113 (27%), Positives = 50/113 (44%), Gaps = 13/113 (11%) Frame = +1 Query: 199 VATSSRDKTVRFW-----------TQHPEKKRE-YVLSKTLVGHSSFVGPMVWAPPSDRF 342 +A+ S DK + W T +K E + TL GH V + W+P +D + Sbjct: 85 LASGSDDKLIMIWRKSAGSSGVFGTGGMQKNHESWKCFYTLRGHDGDVLDLAWSP-NDVY 143 Query: 343 PEGAIVSGGMDTQVLLWNLHT-GEVAGTMKGHTSQVTGLAIDDNGDIISSSMD 498 + S +D V++W+ T+KGHT V G++ D G ++S D Sbjct: 144 ----LASCSIDNTVIIWDAQAFPHSVATLKGHTGLVKGVSWDPLGRFLASQSD 192
>WDR7_HUMAN (Q9Y4E6) WD-repeat protein 7 (TGF-beta resistance-associated| protein TRAG) (Rabconnectin-3 beta) Length = 1490 Score = 38.1 bits (87), Expect = 0.013 Identities = 21/93 (22%), Positives = 48/93 (51%), Gaps = 1/93 (1%) Frame = +1 Query: 187 GDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPP-SDRFPEGAIVS 363 G + + +++ V+ +R + +TL GH + V +++ S R+ + ++S Sbjct: 428 GSIVIVPATQTAIVQLLQGEHMLRRGWPPHRTLRGHRNKVTCLLYPHQVSARYDQRYLIS 487 Query: 364 GGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAI 462 GG+D V++W++ +GE+ H ++T L + Sbjct: 488 GGVDFSVIIWDIFSGEMKHIFCVHGGEITQLLV 520
>WDR1_DROME (Q9VU68) Putative actin-interacting protein 1 (AIP1)| Length = 608 Score = 38.1 bits (87), Expect = 0.013 Identities = 22/72 (30%), Positives = 36/72 (50%), Gaps = 2/72 (2%) Frame = +1 Query: 292 HSSFVGPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGH--TSQVTGLAID 465 HS+ V + W+P S + SG +DT +++W++ +K SQ+T L Sbjct: 532 HSARVNTVAWSPNSL-----LVASGSLDTTIIIWSVANPAKHTIIKNAHPQSQITRLVWL 586 Query: 466 DNGDIISSSMDC 501 DN +IS+ DC Sbjct: 587 DNNTVISTGQDC 598
>PRP4_MOUSE (Q9DAW6) U4/U6 small nuclear ribonucleoprotein Prp4 (U4/U6 snRNP 60| kDa protein) (WD splicing factor Prp4) Length = 521 Score = 38.1 bits (87), Expect = 0.013 Identities = 30/116 (25%), Positives = 51/116 (43%), Gaps = 1/116 (0%) Frame = +1 Query: 145 LHGHEDDVRGICICGD-VGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVW 321 L GH ++ GI + +AT S D T + W ++R V T+ H + V + + Sbjct: 402 LEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDL---RQRRCVY--TIPAHQNLVTGVKF 456 Query: 322 APPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISS 489 P F +++G D +W T+ GH +V GL I +G +I++ Sbjct: 457 EPIHGDF----LLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLIAT 508 Score = 33.1 bits (74), Expect = 0.43 Identities = 22/77 (28%), Positives = 38/77 (49%), Gaps = 3/77 (3%) Frame = +1 Query: 271 LSKTLVGHSSFVGPMVWAPPSDRFPEGA---IVSGGMDTQVLLWNLHTGEVAGTMKGHTS 441 L TL GH++ VG +V+ P S + + S D V LW+L + E ++GHT Sbjct: 264 LLHTLRGHNTNVGAIVFHPKSTVSLDQKDVNLASCAADGSVKLWSLDSDEPVADIEGHTV 323 Query: 442 QVTGLAIDDNGDIISSS 492 +V + +G + ++ Sbjct: 324 RVARVMWHPSGRFLGTT 340 Score = 32.3 bits (72), Expect = 0.73 Identities = 23/93 (24%), Positives = 44/93 (47%), Gaps = 1/93 (1%) Frame = +1 Query: 199 VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIV-SGGMD 375 + T+ D++ R W + E +L + GHS V + + +G++ +GG+D Sbjct: 337 LGTTCYDRSWRLWDLEAQ---EEILHQE--GHSMGVYDIAF------HQDGSLAGTGGLD 385 Query: 376 TQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNG 474 +W+L TG ++GH ++ G+ NG Sbjct: 386 AFGRVWDLRTGRCIMFLEGHLKEIYGINFSPNG 418 Score = 31.2 bits (69), Expect = 1.6 Identities = 24/97 (24%), Positives = 44/97 (45%) Frame = +1 Query: 190 DVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGG 369 DV +A+ + D +V+ W+ ++ + GH+ V ++W P S RF + + Sbjct: 292 DVNLASCAADGSVKLWSLDSDEP-----VADIEGHTVRVARVMWHP-SGRF----LGTTC 341 Query: 370 MDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDI 480 D LW+L E +GH+ V +A +G + Sbjct: 342 YDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSL 378
>TBL1X_HUMAN (O60907) F-box-like/WD-repeat protein TBL1X (Transducin beta-like| 1X protein) (Transducin-beta-like 1, X-linked) (SMAP55) Length = 526 Score = 38.1 bits (87), Expect = 0.013 Identities = 26/100 (26%), Positives = 41/100 (41%) Frame = +1 Query: 199 VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDT 378 +AT S D R WT+ L+ TL H + + W + I+S G+D Sbjct: 252 LATGSYDGFARIWTEDGN------LASTLGQHKGPIFALKWNRKGNY-----ILSAGVDK 300 Query: 379 QVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSSMD 498 ++W+ HTGE H++ + +N S S D Sbjct: 301 TTIIWDAHTGEAKQQFPFHSAPALDVDWQNNTTFASCSTD 340 Score = 29.6 bits (65), Expect = 4.7 Identities = 21/71 (29%), Positives = 30/71 (42%), Gaps = 3/71 (4%) Frame = +1 Query: 283 LVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMK---GHTSQVTG 453 L GH S V W P SD + SG D+ +WNL+ G+ + H + G Sbjct: 177 LRGHESEVFICAWNPVSD-----LLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGG 231 Query: 454 LAIDDNGDIIS 486 + N D+ S Sbjct: 232 HDVPSNKDVTS 242
>WDR7_MOUSE (Q920I9) WD-repeat protein 7 (TGF-beta resistance-associated| protein TRAG) Length = 1489 Score = 37.7 bits (86), Expect = 0.017 Identities = 21/93 (22%), Positives = 48/93 (51%), Gaps = 1/93 (1%) Frame = +1 Query: 187 GDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPP-SDRFPEGAIVS 363 G + + +++ V+ +R + +TL GH + V +++ S R+ + ++S Sbjct: 428 GSIIIVPATQTAIVQLLQGEHMLRRGWPPHRTLRGHRNKVTCLLYPHQVSARYDQRYLIS 487 Query: 364 GGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAI 462 GG+D V++W++ +GE+ H ++T L + Sbjct: 488 GGVDFSVIIWDIFSGEMKHIFCVHGGEITQLLV 520
>TEP1_HUMAN (Q99973) Telomerase protein component 1 (Telomerase-associated| protein 1) (Telomerase protein 1) (p240) (p80 telomerase homolog) Length = 2627 Score = 37.7 bits (86), Expect = 0.017 Identities = 32/120 (26%), Positives = 50/120 (41%), Gaps = 1/120 (0%) Frame = +1 Query: 142 QLHGHEDDVRGICICGDVG-VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMV 318 +L GHE V D G +AT RD+++ W K + S H +V Sbjct: 2056 ELRGHEGPVSCCSFSTDGGSLATGGRDRSLLCWDVRTPKTPVLIHSFPAC-HRDWVTGCA 2114 Query: 319 WAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSSMD 498 W + ++S D V LW+ +G+ G GH S V+ +A + ++S S D Sbjct: 2115 WTK------DNLLISCSSDGSVGLWDPESGQRLGQFLGHQSAVSAVAAVEE-HVVSVSRD 2167
>WDR31_HUMAN (Q8NA23) WD-repeat protein 31| Length = 367 Score = 37.7 bits (86), Expect = 0.017 Identities = 24/88 (27%), Positives = 42/88 (47%), Gaps = 1/88 (1%) Frame = +1 Query: 151 GHEDDVRGI-CICGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAP 327 GHE ++ + CI ++SRD+ V W H + + L GH+ V + +P Sbjct: 101 GHEHEITKVACIPKSSQFFSASRDRMVMMWDLHGSSQPR----QQLCGHAMVVTGLAVSP 156 Query: 328 PSDRFPEGAIVSGGMDTQVLLWNLHTGE 411 S + + +G D +LLW++ TG+ Sbjct: 157 DSSQ-----LCTGSRDNTLLLWDVVTGQ 179 Score = 35.0 bits (79), Expect = 0.11 Identities = 19/48 (39%), Positives = 26/48 (54%), Gaps = 1/48 (2%) Frame = +1 Query: 358 VSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLA-IDDNGDIISSSMD 498 VSGG D V+ +N TG V KGH ++T +A I + S+S D Sbjct: 77 VSGGKDKTVVAYNWKTGNVVKRFKGHEHEITKVACIPKSSQFFSASRD 124
>HAT2_SCHPO (O94244) Histone acetyltransferase type B subunit 2 (EC 2.3.1.48)| Length = 430 Score = 37.7 bits (86), Expect = 0.017 Identities = 25/87 (28%), Positives = 38/87 (43%), Gaps = 2/87 (2%) Frame = +1 Query: 145 LHGHEDDVRGICI--CGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMV 318 + H + + I D +AT+S DKTV W + + Y TL GH V + Sbjct: 277 IQAHSKAINAVAINPFNDYLLATASADKTVALW----DLRNPYQRLHTLEGHEDEVYGLE 332 Query: 319 WAPPSDRFPEGAIVSGGMDTQVLLWNL 399 W+P E + S D +V +W+L Sbjct: 333 WSP----HDEPILASSSTDRRVCIWDL 355
>WSB1_MOUSE (O54927) WD repeat and SOCS box-containing protein 1 (WSB-1)| Length = 421 Score = 37.7 bits (86), Expect = 0.017 Identities = 29/122 (23%), Positives = 54/122 (44%), Gaps = 2/122 (1%) Frame = +1 Query: 133 LSAQLHGHEDDVRGICIC--GDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFV 306 L L H + VR + G + + ++SRDKT+R W + K + + K L H ++V Sbjct: 162 LLLNLVDHIEMVRDLTFAPDGSLLLVSASRDKTLRVW----DLKDDGNMVKVLRAHQNWV 217 Query: 307 GPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIIS 486 ++P + S G V LWN+ + ++GH V +G +++ Sbjct: 218 YSCAFSPDCSM-----LCSVGASKAVFLWNMDKYTMIRKLEGHHHDVVACDFSPDGALLA 272 Query: 487 SS 492 ++ Sbjct: 273 TA 274
>WDR7_RAT (Q9ERH3) WD-repeat protein 7 (TGF-beta resistance-associated| protein TRAG) Length = 1488 Score = 37.7 bits (86), Expect = 0.017 Identities = 21/93 (22%), Positives = 48/93 (51%), Gaps = 1/93 (1%) Frame = +1 Query: 187 GDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPP-SDRFPEGAIVS 363 G + + +++ V+ +R + +TL GH + V +++ S R+ + ++S Sbjct: 428 GSIIIVPATQTAIVQLLQGEHMLRRGWPPHRTLRGHRNKVTCLLYPHQVSARYDQRYLIS 487 Query: 364 GGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAI 462 GG+D V++W++ +GE+ H ++T L + Sbjct: 488 GGVDFSVIIWDIFSGEMKHIFCVHGGEITQLLV 520
>PK1IP_BRARE (Q6TNS2) p21-activated protein kinase-interacting protein 1-like| (PAK1-interacting protein 1-like) Length = 368 Score = 37.7 bits (86), Expect = 0.017 Identities = 25/97 (25%), Positives = 47/97 (48%) Frame = +1 Query: 199 VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDT 378 +AT S+D+T++ + KK E+ L+ H + + + S ++SGG D Sbjct: 60 IATGSKDETIQLYDMC--KKTEH---GALLHHDGTISCLEFYGTSH------LLSGGQDG 108 Query: 379 QVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISS 489 + +W+ E T++ H QVT L++ +G + S Sbjct: 109 LICVWSTKKWECLKTIRAHKGQVTSLSVHPSGKLALS 145
>POP3_SCHPO (O74184) WD-repeat protein pop3 (WD-repeat protein wat1)| Length = 314 Score = 37.4 bits (85), Expect = 0.023 Identities = 24/90 (26%), Positives = 39/90 (43%) Frame = +1 Query: 199 VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDT 378 +AT S D TV W+ + ++L + L GH +V ++ S +V+ D Sbjct: 230 LATCSADATVNIWST---EDMSFMLERRLQGHQRWVWDCAFSADSTY-----LVTASSDH 281 Query: 379 QVLLWNLHTGEVAGTMKGHTSQVTGLAIDD 468 LW L +GE GH +A++D Sbjct: 282 VARLWELSSGETIRQYSGHHKAAVCVALND 311 Score = 30.0 bits (66), Expect = 3.6 Identities = 25/85 (29%), Positives = 37/85 (43%), Gaps = 2/85 (2%) Frame = +1 Query: 151 GHEDDVRGICI-CGDVGVATSSRDKTVRFWTQH-PEKKREYVLSKTLVGHSSFVGPMVWA 324 GH ++V I C +ATSS D TV+ W P +R Y H S V ++ Sbjct: 81 GHTNNVTAIAFHCDGKWLATSSEDGTVKVWDMRAPSVQRNY-------DHKSPVNDLLIH 133 Query: 325 PPSDRFPEGAIVSGGMDTQVLLWNL 399 P +G ++S +V W+L Sbjct: 134 P-----NQGELLSCDQSGRVRAWDL 153
>YQF1_SCHPO (O94394) Hypothetical WD-repeat protein C126.01c in chromosome III| Length = 369 Score = 37.4 bits (85), Expect = 0.023 Identities = 26/78 (33%), Positives = 37/78 (47%), Gaps = 4/78 (5%) Frame = +1 Query: 277 KTLVGHSSFVGPMVWAPPSDRFPEGA---IVSGGMDTQVLLWNLHTGEVAGTMKGHTSQV 447 KT GHS GP+ +G I +G D + WN+ TGE T+ GHT V Sbjct: 79 KTYKGHS---GPVTCCQIESLRKDGKVRHIYTGSWDHTIKKWNVSTGECVETLIGHTDYV 135 Query: 448 TG-LAIDDNGDIISSSMD 498 L +++ G ++S S D Sbjct: 136 KCLLLLEEEGLLLSGSTD 153 Score = 35.8 bits (81), Expect = 0.066 Identities = 31/120 (25%), Positives = 54/120 (45%), Gaps = 4/120 (3%) Frame = +1 Query: 151 GHEDDVRGICICGDV----GVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMV 318 GH+ +V C+ D + T+S DKTVR W+ + + + +T + H ++ Sbjct: 220 GHQSNV--YCLLFDPQDSEALWTASADKTVREWSLY-----QGIHEETRMEHPDVCTDVL 272 Query: 319 WAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSSMD 498 +G I + D ++ +W+ TG V GH VT + + +ISSS+D Sbjct: 273 ------TLADGNIATACRDEEIRVWDTTTGNVKDIYSGHYESVTKI-LQWKSYLISSSLD 325
>APAF_HUMAN (O14727) Apoptotic protease-activating factor 1 (Apaf-1)| Length = 1248 Score = 37.4 bits (85), Expect = 0.023 Identities = 32/119 (26%), Positives = 50/119 (42%), Gaps = 3/119 (2%) Frame = +1 Query: 142 QLHGHEDDVRGICIC---GDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGP 312 ++ HED+V +C D +AT S DK V+ W + L T HS V Sbjct: 652 EIKAHEDEV--LCCAFSTDDRFIATCSVDKKVKIWNSMTGE-----LVHTYDEHSEQVNC 704 Query: 313 MVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISS 489 + S + +G D + LW+L+ E TM GHT+ V + +++S Sbjct: 705 CHFTNSSHHL---LLATGSSDCFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLAS 760
>KTNB1_HUMAN (Q9BVA0) Katanin p80 WD40-containing subunit B1 (Katanin p80| subunit B1) (p80 katanin) Length = 655 Score = 37.4 bits (85), Expect = 0.023 Identities = 26/119 (21%), Positives = 51/119 (42%), Gaps = 1/119 (0%) Frame = +1 Query: 145 LHGHEDDVRGICI-CGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVW 321 L GH V + + + + S+ ++R W K + +TL+GH + + + + Sbjct: 59 LTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAAK-----ILRTLMGHKANICSLDF 113 Query: 322 APPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSSMD 498 P + + SG DT + LW++ +GH+ V L +G ++S+ D Sbjct: 114 HPYGE-----FVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAAD 167 Score = 36.2 bits (82), Expect = 0.051 Identities = 25/97 (25%), Positives = 44/97 (45%) Frame = +1 Query: 199 VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDT 378 +AT D V W+ + K ++S L GH+S V + PE IV+G Sbjct: 36 LATGGDDCRVNLWSIN---KPNCIMS--LTGHTSPVESVRL-----NTPEELIVAGSQSG 85 Query: 379 QVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISS 489 + +W+L ++ T+ GH + + L G+ ++S Sbjct: 86 SIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVAS 122 Score = 30.8 bits (68), Expect = 2.1 Identities = 24/97 (24%), Positives = 44/97 (45%) Frame = +1 Query: 199 VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDT 378 VA+ S+D ++ W + +R+ + + GHS V + ++P + S D Sbjct: 120 VASGSQDTNIKLW----DIRRKGCVFRYR-GHSQAVRCLRFSPDGKW-----LASAADDH 169 Query: 379 QVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISS 489 V LW+L G++ GHT V + N +++S Sbjct: 170 TVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLAS 206
>NUDF_EMENI (Q00664) Nuclear migration protein nudF| Length = 444 Score = 37.4 bits (85), Expect = 0.023 Identities = 28/73 (38%), Positives = 40/73 (54%), Gaps = 3/73 (4%) Frame = +1 Query: 145 LHGHEDDVRGICI-CGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVG-HSSFVGPMV 318 LHGH++ VRG+ G + + S DKT+R W + +E L KT+ G H FV + Sbjct: 345 LHGHDNWVRGLVFHPGGKYLFSVSDDKTIRCW----DLSQEGRLVKTISGAHEHFVSCIR 400 Query: 319 WAP-PSDRFPEGA 354 WAP P+ P+ A Sbjct: 401 WAPSPNTDNPDPA 413 Score = 35.8 bits (81), Expect = 0.066 Identities = 27/116 (23%), Positives = 46/116 (39%), Gaps = 16/116 (13%) Frame = +1 Query: 199 VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSD----------RFPE 348 + + RD+ + W + + L+GH +F+ V+APP+ + P Sbjct: 260 LVSGGRDQAITVWEVSSAEPKA-----ALLGHENFIECCVFAPPASYEHLATLAGLKKPP 314 Query: 349 GA------IVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSSMD 498 A + +G D + LW G + T+ GH + V GL G + S D Sbjct: 315 PATSSCEFVATGARDKTIKLWEAR-GRLIKTLHGHDNWVRGLVFHPGGKYLFSVSD 369 Score = 33.5 bits (75), Expect = 0.33 Identities = 13/35 (37%), Positives = 21/35 (60%) Frame = +1 Query: 352 AIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGL 456 ++ SG D + +W+ GE+ T+KGH V+GL Sbjct: 128 SLASGSEDCTIKIWDWELGEIERTLKGHIRGVSGL 162 Score = 32.7 bits (73), Expect = 0.56 Identities = 24/79 (30%), Positives = 36/79 (45%), Gaps = 1/79 (1%) Frame = +1 Query: 199 VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDT 378 VAT +RDKT++ W L KTL GH ++V +V+ P + S D Sbjct: 323 VATGARDKTIKLWEARGR------LIKTLHGHDNWVRGLVFHPGGK-----YLFSVSDDK 371 Query: 379 QVLLWNL-HTGEVAGTMKG 432 + W+L G + T+ G Sbjct: 372 TIRCWDLSQEGRLVKTISG 390 Score = 31.6 bits (70), Expect = 1.2 Identities = 25/99 (25%), Positives = 42/99 (42%), Gaps = 2/99 (2%) Frame = +1 Query: 145 LHGHEDDVRGI--CICGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMV 318 L GH+ V + D + ++SRD T+R W + + S T S++ + Sbjct: 197 LSGHDHSVSSVRFLTSNDNHLISASRDGTLRIWDVSTGFCVKVIKSAT----ESWIRDV- 251 Query: 319 WAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGH 435 S F +VSGG D + +W + + E + GH Sbjct: 252 ----SPSFDGKWLVSGGRDQAITVWEVSSAEPKAALLGH 286
>PRP4_ARATH (O22212) U4/U6 small nuclear ribonucleoprotein PRP4-like protein| Length = 554 Score = 37.4 bits (85), Expect = 0.023 Identities = 25/97 (25%), Positives = 47/97 (48%) Frame = +1 Query: 199 VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDT 378 +AT+S D+T + W K + L +T GH + + + P S ++ + + D Sbjct: 313 LATASADRTAKLW------KTDGTLLQTFEGHLDRLARVAFHP-SGKY----LGTTSYDK 361 Query: 379 QVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISS 489 LW+++TG +GH+ V G+A +G + +S Sbjct: 362 TWRLWDINTGAELLLQEGHSRSVYGIAFQQDGALAAS 398 Score = 32.3 bits (72), Expect = 0.73 Identities = 27/98 (27%), Positives = 45/98 (45%), Gaps = 1/98 (1%) Frame = +1 Query: 199 VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSG-GMD 375 + T+S DKT R W + E +L + GHS V + + +GA+ + G+D Sbjct: 354 LGTTSYDKTWRLWDINTGA--ELLLQE---GHSRSVYGIAFQQ------DGALAASCGLD 402 Query: 376 TQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISS 489 + +W+L TG +GH V + NG ++S Sbjct: 403 SLARVWDLRTGRSILVFQGHIKPVFSVNFSPNGYHLAS 440 Score = 30.8 bits (68), Expect = 2.1 Identities = 15/39 (38%), Positives = 21/39 (53%), Gaps = 1/39 (2%) Frame = +1 Query: 127 YHLSAQLHGHEDDVRGICICGDVG-VATSSRDKTVRFWT 240 + L L GHE V + I D +AT S D+T++ WT Sbjct: 498 FSLVKSLAGHESKVASLDITADSSCIATVSHDRTIKLWT 536
>KTNB1_MOUSE (Q8BG40) Katanin p80 WD40-containing subunit B1 (Katanin p80| subunit B1) (p80 katanin) Length = 658 Score = 37.4 bits (85), Expect = 0.023 Identities = 26/119 (21%), Positives = 51/119 (42%), Gaps = 1/119 (0%) Frame = +1 Query: 145 LHGHEDDVRGICI-CGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVW 321 L GH V + + + + S+ ++R W K + +TL+GH + + + + Sbjct: 59 LTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAAK-----ILRTLMGHKANICSLDF 113 Query: 322 APPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSSMD 498 P + + SG DT + LW++ +GH+ V L +G ++S+ D Sbjct: 114 HPYGE-----FVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAAD 167 Score = 36.2 bits (82), Expect = 0.051 Identities = 25/97 (25%), Positives = 44/97 (45%) Frame = +1 Query: 199 VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDT 378 +AT D V W+ + K ++S L GH+S V + PE IV+G Sbjct: 36 LATGGDDCRVNLWSIN---KPNCIMS--LTGHTSPVESVRL-----NTPEELIVAGSQSG 85 Query: 379 QVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISS 489 + +W+L ++ T+ GH + + L G+ ++S Sbjct: 86 SIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVAS 122 Score = 30.8 bits (68), Expect = 2.1 Identities = 24/97 (24%), Positives = 44/97 (45%) Frame = +1 Query: 199 VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDT 378 VA+ S+D ++ W + +R+ + + GHS V + ++P + S D Sbjct: 120 VASGSQDTNIKLW----DIRRKGCVFRYR-GHSQAVRCLRFSPDGKW-----LASAADDH 169 Query: 379 QVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISS 489 V LW+L G++ GHT V + N +++S Sbjct: 170 TVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLAS 206
>CORO_YEAST (Q06440) Coronin-like protein| Length = 651 Score = 37.4 bits (85), Expect = 0.023 Identities = 22/71 (30%), Positives = 38/71 (53%) Frame = +1 Query: 277 KTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGL 456 K L GH+ VG +++ P + E + S D V LWN+ TG+ T+K H VT + Sbjct: 134 KFLTGHARKVGHVLYHPVA----ENVLASSSGDYTVKLWNVETGKDMITLK-HPDMVTSM 188 Query: 457 AIDDNGDIISS 489 + +G+ +++ Sbjct: 189 SFSYDGNYLAT 199
>PRP4_YEAST (P20053) U4/U6 small nuclear ribonucleoprotein PRP4| Length = 465 Score = 37.4 bits (85), Expect = 0.023 Identities = 25/92 (27%), Positives = 43/92 (46%) Frame = +1 Query: 199 VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDT 378 + ++S D T R W + E +L + GH V + S + + SGGMD+ Sbjct: 280 IGSASHDMTWRLWDASTHQ--ELLLQE---GHDKGVFSL-----SFQCDGSLVCSGGMDS 329 Query: 379 QVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNG 474 +LW++ +G T+ GH+ + +A NG Sbjct: 330 LSMLWDIRSGSKVMTLAGHSKPIYTVAWSPNG 361
>PK1IP_XENLA (Q68FJ6) p21-activated protein kinase-interacting protein 1-like| (PAK1-interacting protein 1-like) Length = 363 Score = 37.4 bits (85), Expect = 0.023 Identities = 30/114 (26%), Positives = 52/114 (45%) Frame = +1 Query: 148 HGHEDDVRGICICGDVGVATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAP 327 H H V + + + VAT SRD+T++ + +KK E+ L+ H+ + + + Sbjct: 37 HAHTASVSVLAV-NNRFVATGSRDETIQIYDM--KKKVEH---GALLHHNGTITCLEF-- 88 Query: 328 PSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISS 489 + ++SG D + +WN E T K H QV L+I +G + S Sbjct: 89 ----YGNTHLLSGAEDGLICVWNTKKWECQQTFKAHKGQVLSLSIHPSGKLALS 138
>GBB_MAIZE (P49178) Guanine nucleotide-binding protein beta subunit| Length = 380 Score = 37.4 bits (85), Expect = 0.023 Identities = 22/75 (29%), Positives = 34/75 (45%) Frame = +1 Query: 262 EYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKGHTS 441 + V +TL GHS V + W P + IVS D ++++WN T + +K H Sbjct: 55 DLVCCRTLQGHSGKVYSLDWTPEKNW-----IVSASQDGRLIVWNALTSQKTHAIKLHCP 109 Query: 442 QVTGLAIDDNGDIIS 486 V A NG ++ Sbjct: 110 WVMACAFAPNGQSVA 124
>PWP2_HUMAN (Q15269) Periodic tryptophan protein 2 homolog| Length = 919 Score = 37.0 bits (84), Expect = 0.030 Identities = 26/83 (31%), Positives = 42/83 (50%), Gaps = 1/83 (1%) Frame = +1 Query: 253 KKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDTQVLLWNLHTGEVAGTMKG 432 + YVL + GH + + + ++P IV+GG D +V +WN +G T Sbjct: 361 QSESYVLKQQ--GHFNSMVALAYSPDGQY-----IVTGGDDGKVKVWNTLSGFCFVTFTE 413 Query: 433 HTSQVTGLAIDDNG-DIISSSMD 498 H+S VTG+ G +++SSMD Sbjct: 414 HSSGVTGVTFTATGYVVVTSSMD 436 Score = 33.5 bits (75), Expect = 0.33 Identities = 26/100 (26%), Positives = 42/100 (42%), Gaps = 2/100 (2%) Frame = +1 Query: 199 VATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVWAPPSDRFPEGAIVSGGMDT 378 V TSS D TVR + H Y +T V S G IVS G Sbjct: 430 VVTSSMDGTVRAFDLH-----RYRNFRTFTSPRPTQFSCVAVDAS-----GEIVSAGAQD 479 Query: 379 --QVLLWNLHTGEVAGTMKGHTSQVTGLAIDDNGDIISSS 492 ++ +W++ TG + + GH ++GL + +++S+ Sbjct: 480 SFEIFVWSMQTGRLLDVLSGHEGPISGLCFNPMKSVLASA 519 Score = 32.7 bits (73), Expect = 0.56 Identities = 28/110 (25%), Positives = 45/110 (40%), Gaps = 7/110 (6%) Frame = +1 Query: 145 LHGHEDDVRGICICGDVGV-ATSSRDKTVRFWTQHPEKKREYVLSKTLVGHSSFVGPMVW 321 L GHE + G+C V A++S DKTVR W + + L+ T Sbjct: 497 LSGHEGPISGLCFNPMKSVLASASWDKTVRLWDMFDSWRTKETLALT------------- 543 Query: 322 APPSDRF-----PEGA-IVSGGMDTQVLLWNLHTGEVAGTMKGHTSQVTG 453 SD P+GA + +++Q+ W+ G+++G TG Sbjct: 544 ---SDALAVTFRPDGAELAVATLNSQITFWDPENAVQTGSIEGRHDLKTG 590 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 68,848,088 Number of Sequences: 219361 Number of extensions: 1425191 Number of successful extensions: 6611 Number of sequences better than 10.0: 423 Number of HSP's better than 10.0 without gapping: 5237 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 6206 length of database: 80,573,946 effective HSP length: 104 effective length of database: 57,760,402 effective search space used: 3581144924 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)